locus-tag	class	description
AT395_RS00005	COG0582	viral genome integration into host DNA
AT395_RS00055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AT395_RS00220	COG3951	Flagellar rod assembly protein muramidase FlgJ
AT395_RS00220	COG1705	Flagellar rod assembly protein muramidase FlgJ
AT395_RS00275	COG0305	Participates in initiation and elongation during chromosome replication
AT395_RS00365	COG4386	tail sheath protein
AT395_RS00510	COG2391	methyltransferase activity
AT395_RS00525	COG0823	Involved in the tonB-independent uptake of proteins
AT395_RS00535	COG0848	biopolymer transport protein
AT395_RS00545	COG0824	Thioesterase
AT395_RS00550	COG2084	Dehydrogenase
AT395_RS00555	COG1414	Transcriptional regulator
AT395_RS00600	COG2808	Putative FMN-binding domain
AT395_RS00635	COG0543	2 iron, 2 sulfur cluster binding
AT395_RS00640	COG2814	Major facilitator Superfamily
AT395_RS00685	COG2814	Major facilitator Superfamily
AT395_RS00690	COG0583	DNA-binding transcription factor activity
AT395_RS00705	COG4695	Portal protein
AT395_RS00720	COG0582	viral genome integration into host DNA
AT395_RS00735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AT395_RS00745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AT395_RS00750	COG0686	Belongs to the AlaDH PNT family
AT395_RS00755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AT395_RS00790	COG0228	four-way junction DNA binding
AT395_RS00795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AT395_RS00800	COG0336	Belongs to the RNA methyltransferase TrmD family
AT395_RS00805	COG0335	large ribosomal subunit rRNA binding
AT395_RS00810	COG0494	nUDIX hydrolase
AT395_RS00815	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AT395_RS00820	COG1162	GTPase activity
AT395_RS00825	COG0501	Belongs to the peptidase M48B family
AT395_RS00830	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AT395_RS00835	COG0521	Mo-molybdopterin cofactor biosynthetic process
AT395_RS00845	COG0312	modulator of DNA gyrase
AT395_RS00875	COG2203	Gaf domain
AT395_RS00875	COG5001	Diguanylate cyclase
AT395_RS00875	COG4251	negative regulation of phosphorylation
AT395_RS00875	COG3706	GGDEF domain
AT395_RS00885	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AT395_RS00890	COG3842	ATPase activity
AT395_RS00895	COG1178	ABC-type Fe3 transport system permease component
AT395_RS00900	COG0583	DNA-binding transcription factor activity
AT395_RS00915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AT395_RS00920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AT395_RS00930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AT395_RS00945	COG0415	Belongs to the DNA photolyase family
AT395_RS00955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AT395_RS00975	COG2153	protein acetylation
AT395_RS00980	COG0488	(ABC) transporter
AT395_RS00995	COG0741	lytic transglycosylase activity
AT395_RS00995	COG1196	nuclear chromosome segregation
AT395_RS00995	COG0739	heme binding
AT395_RS01010	COG0583	DNA-binding transcription factor activity
AT395_RS01015	COG2814	Major facilitator Superfamily
AT395_RS01025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT395_RS01030	COG0697	spore germination
AT395_RS01065	COG4106	trans-aconitate 2-methyltransferase activity
AT395_RS01075	COG3135	benzoate transporter
AT395_RS01085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AT395_RS01110	COG0778	Nitroreductase
AT395_RS01115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AT395_RS01120	COG2878	Part of a membrane complex involved in electron transport
AT395_RS01125	COG1309	transcriptional regulator
AT395_RS01140	COG0556	nucleotide-excision repair
AT395_RS01145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AT395_RS01150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AT395_RS01165	COG1104	cysteine desulfurase activity
AT395_RS01170	COG0822	iron-sulfur transferase activity
AT395_RS01175	COG0316	Belongs to the HesB IscA family
AT395_RS01180	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AT395_RS01215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AT395_RS01225	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AT395_RS01260	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AT395_RS01280	COG0084	hydrolase, TatD family'
AT395_RS01290	COG2267	carboxylic ester hydrolase activity
AT395_RS01295	COG0504	CTP synthase activity
AT395_RS01300	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AT395_RS01305	COG0148	phosphopyruvate hydratase activity
AT395_RS01310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AT395_RS01320	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AT395_RS01330	COG2833	Protein of unknown function (DUF455)
AT395_RS01335	COG2267	carboxylic ester hydrolase activity
AT395_RS01340	COG0613	PHP domain protein
AT395_RS01345	COG0009	L-threonylcarbamoyladenylate synthase
AT395_RS01350	COG1994	Peptidase M50
AT395_RS01355	COG0180	Tryptophanyl-tRNA synthetase
AT395_RS01360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AT395_RS01365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AT395_RS01370	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AT395_RS01380	COG2850	peptidyl-arginine hydroxylation
AT395_RS01395	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AT395_RS01400	COG5002	protein histidine kinase activity
AT395_RS01400	COG3447	MASE1 domain protein
AT395_RS01400	COG5001	Diguanylate cyclase
AT395_RS01410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AT395_RS01410	COG0604	alcohol dehydrogenase
AT395_RS01410	COG3321	synthase
AT395_RS01410	COG4221	oxidoreductase activity
AT395_RS01415	COG0149	triose-phosphate isomerase activity
AT395_RS01430	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AT395_RS01450	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AT395_RS01460	COG1034	ATP synthesis coupled electron transport
AT395_RS01465	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AT395_RS01470	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AT395_RS01480	COG0713	ATP synthesis coupled electron transport
AT395_RS01495	COG1007	ATP synthesis coupled electron transport
AT395_RS01525	COG0625	glutathione transferase activity
AT395_RS01530	COG1960	acyl-CoA dehydrogenase activity
AT395_RS01545	COG1024	Enoyl-CoA hydratase
AT395_RS01550	COG1250	3-hydroxyacyl-CoA dehydrogenase
AT395_RS01560	COG0625	glutathione transferase activity
AT395_RS01565	COG0436	Aminotransferase
AT395_RS01575	COG3022	response to hydroperoxide
AT395_RS01580	COG2866	Carboxypeptidase
AT395_RS01590	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AT395_RS01610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AT395_RS01620	COG0039	L-malate dehydrogenase activity
AT395_RS01625	COG2188	Transcriptional regulator
AT395_RS01640	COG1053	succinate dehydrogenase
AT395_RS01645	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AT395_RS01650	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AT395_RS01655	COG0372	Belongs to the citrate synthase family
AT395_RS01660	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AT395_RS01670	COG0066	3-isopropylmalate dehydratase activity
AT395_RS01675	COG0473	3-isopropylmalate dehydrogenase activity
AT395_RS01680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AT395_RS01690	COG0101	tRNA pseudouridine synthase activity
AT395_RS01695	COG0135	phosphoribosylanthranilate isomerase activity
AT395_RS01700	COG0133	tryptophan synthase activity
AT395_RS01710	COG0159	tryptophan synthase activity
AT395_RS01715	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AT395_RS01720	COG0285	dihydrofolate synthase activity
AT395_RS01745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AT395_RS01760	COG2194	sulfuric ester hydrolase activity
AT395_RS01765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AT395_RS01765	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AT395_RS01770	COG3708	Transcriptional regulator
AT395_RS01770	COG2207	Transcriptional regulator
AT395_RS01775	COG0431	NADPH-dependent FMN reductase
AT395_RS01780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AT395_RS01785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS01790	COG1116	anion transmembrane transporter activity
AT395_RS01800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AT395_RS01805	COG0483	inositol monophosphate 1-phosphatase activity
AT395_RS01815	COG1045	serine acetyltransferase
AT395_RS01820	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AT395_RS01825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AT395_RS01840	COG0215	cysteine-tRNA ligase activity
AT395_RS01845	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AT395_RS01850	COG0825	malonyl-CoA metabolic process
AT395_RS01855	COG0037	tRNA processing
AT395_RS01860	COG2194	sulfuric ester hydrolase activity
AT395_RS01865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AT395_RS01865	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AT395_RS01870	COG2207	Transcriptional regulator
AT395_RS01870	COG3708	Transcriptional regulator
AT395_RS01875	COG0431	NADPH-dependent FMN reductase
AT395_RS01880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AT395_RS01885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS01890	COG1116	anion transmembrane transporter activity
AT395_RS01900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AT395_RS01905	COG0483	inositol monophosphate 1-phosphatase activity
AT395_RS01915	COG1045	serine acetyltransferase
AT395_RS01920	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AT395_RS01925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AT395_RS01940	COG1045	serine acetyltransferase
AT395_RS01945	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AT395_RS01950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AT395_RS01965	COG0215	cysteine-tRNA ligase activity
AT395_RS01970	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AT395_RS01975	COG0825	malonyl-CoA metabolic process
AT395_RS01980	COG0037	tRNA processing
AT395_RS01985	COG0527	aspartate kinase activity
AT395_RS02015	COG4174	ABC transporter (Permease)
AT395_RS02020	COG4239	(ABC) transporter, permease
AT395_RS02025	COG4172	Belongs to the ABC transporter superfamily
AT395_RS02030	COG0791	NLP P60 protein
AT395_RS02035	COG1752	Esterase of the alpha-beta hydrolase superfamily
AT395_RS02040	COG1840	ABC-type Fe3 transport system, periplasmic component
AT395_RS02050	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AT395_RS02065	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AT395_RS02075	COG2204	response regulator
AT395_RS02125	COG2197	response regulator
AT395_RS02130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AT395_RS02145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS02150	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AT395_RS02185	COG0105	UTP biosynthetic process
AT395_RS02190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AT395_RS02200	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AT395_RS02205	COG0124	histidyl-tRNA synthetase
AT395_RS02210	COG2976	Protein conserved in bacteria
AT395_RS02220	COG1160	GTP binding
AT395_RS02225	COG1923	regulation of RNA biosynthetic process
AT395_RS02230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AT395_RS02235	COG0330	HflC and HflK could
AT395_RS02240	COG0330	HflC and HflK could
AT395_RS02245	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AT395_RS02250	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AT395_RS02260	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AT395_RS02270	COG0339	signal peptide processing
AT395_RS02275	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AT395_RS02280	COG4566	intracellular signal transduction
AT395_RS02290	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AT395_RS02295	COG0508	dehydrogenase complex catalyzes the overall conversion of
AT395_RS02305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AT395_RS02315	COG0123	including yeast histone deacetylase and acetoin utilization protein
AT395_RS02320	COG0697	spore germination
AT395_RS02335	COG1414	Transcriptional regulator
AT395_RS02350	COG1139	Iron-sulfur cluster binding protein
AT395_RS02355	COG0765	amino acid transport
AT395_RS02360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT395_RS02365	COG0167	dihydroorotate dehydrogenase activity
AT395_RS02370	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AT395_RS02375	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AT395_RS02400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AT395_RS02430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AT395_RS02450	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AT395_RS02465	COG0435	Glutathione S-transferase
AT395_RS02470	COG1278	Cold shock
AT395_RS02490	COG0679	Auxin Efflux Carrier
AT395_RS02535	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AT395_RS02540	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AT395_RS02545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AT395_RS02550	COG0840	transmembrane signaling receptor activity
AT395_RS02615	COG0174	glutamine synthetase
AT395_RS02625	COG2204	response regulator
AT395_RS02650	COG0307	riboflavin synthase, alpha
AT395_RS02665	COG0387	Pfam Sodium calcium exchanger
AT395_RS02670	COG2186	Transcriptional regulator
AT395_RS02675	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS02685	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS02690	COG2818	Glycosylase
AT395_RS02695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AT395_RS02700	COG1187	pseudouridine synthase activity
AT395_RS02705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS02710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AT395_RS02715	COG1116	anion transmembrane transporter activity
AT395_RS02730	COG2207	Transcriptional regulator
AT395_RS02740	COG0583	DNA-binding transcription factor activity
AT395_RS02755	COG0557	exoribonuclease II activity
AT395_RS02760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AT395_RS02770	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AT395_RS02780	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AT395_RS02785	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AT395_RS02785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AT395_RS02790	COG1643	Atp-dependent helicase
AT395_RS02810	COG1058	Belongs to the CinA family
AT395_RS02810	COG1546	Belongs to the CinA family
AT395_RS02820	COG0583	DNA-binding transcription factor activity
AT395_RS02830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AT395_RS02835	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AT395_RS02840	COG1187	pseudouridine synthase activity
AT395_RS02845	COG0779	Required for maturation of 30S ribosomal subunits
AT395_RS02850	COG0195	Participates in both transcription termination and antitermination
AT395_RS02850	COG2251	uridine kinase activity
AT395_RS02860	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AT395_RS02865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AT395_RS02875	COG2814	Major facilitator Superfamily
AT395_RS02880	COG1566	PFAM secretion protein HlyD family protein
AT395_RS02915	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AT395_RS02920	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AT395_RS02925	COG4208	sulfate ABC transporter
AT395_RS02930	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AT395_RS02935	COG0583	DNA-binding transcription factor activity
AT395_RS02940	COG0252	asparaginase activity
AT395_RS02945	COG2084	Dehydrogenase
AT395_RS02950	COG3622	Belongs to the hyi family
AT395_RS02955	COG3960	tartronate-semialdehyde synthase activity
AT395_RS02960	COG0583	DNA-binding transcription factor activity
AT395_RS02975	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AT395_RS02980	COG0359	binds to the 23S rRNA
AT395_RS02995	COG0306	phosphate transporter
AT395_RS03005	COG0791	NLP P60 protein
AT395_RS03010	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AT395_RS03015	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AT395_RS03025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AT395_RS03025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AT395_RS03035	COG1215	transferase activity, transferring glycosyl groups
AT395_RS03040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AT395_RS03045	COG2076	Multidrug Resistance protein
AT395_RS03050	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AT395_RS03060	COG0436	Aminotransferase
AT395_RS03080	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AT395_RS03085	COG0314	molybdopterin synthase activity
AT395_RS03095	COG0542	response to heat
AT395_RS03105	COG3275	phosphorelay sensor kinase activity
AT395_RS03130	COG0697	spore germination
AT395_RS03135	COG2224	Isocitrate lyase
AT395_RS03145	COG0583	DNA-binding transcription factor activity
AT395_RS03155	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AT395_RS03165	COG0513	Belongs to the DEAD box helicase family
AT395_RS03170	COG1214	PFAM Peptidase M22, glycoprotease
AT395_RS03175	COG1214	PFAM Peptidase M22, glycoprotease
AT395_RS03175	COG0456	acetyltransferase
AT395_RS03180	COG1573	uracil-dna glycosylase
AT395_RS03190	COG0351	phosphomethylpyrimidine kinase
AT395_RS03195	COG0477	Major facilitator Superfamily
AT395_RS03200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AT395_RS03210	COG0488	(ABC) transporter
AT395_RS03220	COG2890	protein-(glutamine-N5) methyltransferase activity
AT395_RS03225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AT395_RS03230	COG1393	Belongs to the ArsC family
AT395_RS03235	COG2171	N-acyltransferase activity
AT395_RS03260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AT395_RS03265	COG0242	peptide deformylase activity
AT395_RS03270	COG1187	pseudouridine synthase activity
AT395_RS03280	COG0024	Methionine aminopeptidase
AT395_RS03285	COG0052	Belongs to the universal ribosomal protein uS2 family
AT395_RS03290	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AT395_RS03305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AT395_RS03315	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AT395_RS03320	COG0750	zinc metalloprotease
AT395_RS03335	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AT395_RS03360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AT395_RS03365	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AT395_RS03380	COG0330	HflC and HflK could
AT395_RS03395	COG2914	Belongs to the UPF0125 (RnfH) family
AT395_RS03415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AT395_RS03415	COG0519	Catalyzes the synthesis of GMP from XMP
AT395_RS03420	COG2226	methyltransferase
AT395_RS03430	COG0583	DNA-binding transcription factor activity
AT395_RS03435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT395_RS03445	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AT395_RS03450	COG0625	glutathione transferase activity
AT395_RS03460	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS03480	COG1566	PFAM secretion protein HlyD family protein
AT395_RS03500	COG0583	DNA-binding transcription factor activity
AT395_RS03560	COG1619	proteins homologs of microcin C7 resistance protein MccF
AT395_RS03570	COG3648	Uricase
AT395_RS03570	COG3195	allantoin biosynthetic process
AT395_RS03575	COG4266	Belongs to the allantoicase family
AT395_RS03585	COG2308	Evidence 4 Homologs of previously reported genes of
AT395_RS03620	COG2233	PERMEase
AT395_RS03630	COG0583	DNA-binding transcription factor activity
AT395_RS03635	COG3845	ABC transporter
AT395_RS03640	COG4603	Belongs to the binding-protein-dependent transport system permease family
AT395_RS03645	COG1079	Belongs to the binding-protein-dependent transport system permease family
AT395_RS03655	COG0488	(ABC) transporter
AT395_RS03680	COG3706	GGDEF domain
AT395_RS03695	COG0789	Transcriptional regulator
AT395_RS03720	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AT395_RS03745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AT395_RS03765	COG3451	type IV secretory pathway VirB4
AT395_RS03780	COG3846	protein secretion by the type IV secretion system
AT395_RS03795	COG2948	multi-organism process
AT395_RS03805	COG2814	Major facilitator Superfamily
AT395_RS03810	COG0534	Mate efflux family protein
AT395_RS03820	COG3550	peptidyl-serine autophosphorylation
AT395_RS03855	COG1538	Outer membrane efflux protein
AT395_RS03905	COG0513	Belongs to the DEAD box helicase family
AT395_RS03925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AT395_RS03930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AT395_RS03955	COG1902	pentaerythritol trinitrate reductase activity
AT395_RS03955	COG0446	pyridine nucleotide-disulphide oxidoreductase
AT395_RS03960	COG3706	GGDEF domain
AT395_RS03965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AT395_RS03970	COG0372	Belongs to the citrate synthase family
AT395_RS04015	COG0798	PFAM Bile acid sodium symporter
AT395_RS04025	COG0640	Transcriptional regulator
AT395_RS04030	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AT395_RS04045	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AT395_RS04065	COG0625	glutathione transferase activity
AT395_RS04080	COG1802	Transcriptional regulator
AT395_RS04095	COG4774	siderophore transport
AT395_RS04100	COG4772	TonB-dependent receptor
AT395_RS04140	COG0583	DNA-binding transcription factor activity
AT395_RS04155	COG0411	ABC transporter
AT395_RS04200	COG1560	Kdo2-lipid A biosynthetic process
AT395_RS04205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AT395_RS04210	COG0165	Argininosuccinate lyase
AT395_RS04220	COG1473	amidohydrolase
AT395_RS04230	COG0583	DNA-binding transcription factor activity
AT395_RS04250	COG1914	H( )-stimulated, divalent metal cation uptake system
AT395_RS04260	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AT395_RS04265	COG1063	alcohol dehydrogenase
AT395_RS04285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AT395_RS04295	COG0589	response to stress
AT395_RS04300	COG0589	response to stress
AT395_RS04310	COG3706	GGDEF domain
AT395_RS04315	COG2186	Transcriptional regulator
AT395_RS04335	COG0543	2 iron, 2 sulfur cluster binding
AT395_RS04355	COG2814	Major facilitator Superfamily
AT395_RS04360	COG0154	amidase activity
AT395_RS04370	COG0579	oxidoreductase
AT395_RS04380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AT395_RS04385	COG2271	Major facilitator Superfamily
AT395_RS04390	COG0179	Fumarylacetoacetate (FAA) hydrolase
AT395_RS04400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS04410	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AT395_RS04425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT395_RS04460	COG1045	serine acetyltransferase
AT395_RS04470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AT395_RS04475	COG0583	DNA-binding transcription factor activity
AT395_RS04480	COG3493	citrate carrier protein
AT395_RS04490	COG2301	Belongs to the HpcH HpaI aldolase family
AT395_RS04515	COG0840	transmembrane signaling receptor activity
AT395_RS04520	COG0583	DNA-binding transcription factor activity
AT395_RS04525	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AT395_RS04545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AT395_RS04590	COG3842	ATPase activity
AT395_RS04595	COG1840	ABC-type Fe3 transport system, periplasmic component
AT395_RS04600	COG1177	transmembrane transport
AT395_RS04610	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS04615	COG2188	Transcriptional regulator
AT395_RS04625	COG2986	histidine ammonia-lyase
AT395_RS04630	COG1113	amino acid transport
AT395_RS04635	COG1228	amidohydrolase
AT395_RS04640	COG0010	Belongs to the arginase family
AT395_RS04645	COG0583	DNA-binding transcription factor activity
AT395_RS04655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS04675	COG3791	Glutathione-dependent formaldehyde-activating
AT395_RS04685	COG2226	methyltransferase
AT395_RS04695	COG1113	amino acid transport
AT395_RS04705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AT395_RS04710	COG0657	acetylesterase activity
AT395_RS04720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS04725	COG0346	lactoylglutathione lyase activity
AT395_RS04735	COG0179	Fumarylacetoacetate (FAA) hydrolase
AT395_RS04740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AT395_RS04760	COG2186	Transcriptional regulator
AT395_RS04780	COG3257	ureidoglycine aminohydrolase activity
AT395_RS04800	COG0402	S-adenosylhomocysteine deaminase activity
AT395_RS04805	COG2197	response regulator
AT395_RS04830	COG0583	DNA-binding transcription factor activity
AT395_RS04850	COG2814	Major facilitator Superfamily
AT395_RS04855	COG1022	Amp-dependent synthetase and ligase
AT395_RS04865	COG3246	L-lysine catabolic process to acetate
AT395_RS04870	COG1250	3-hydroxyacyl-CoA dehydrogenase
AT395_RS04875	COG1024	Enoyl-CoA hydratase
AT395_RS04880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AT395_RS04885	COG1595	DNA-templated transcription, initiation
AT395_RS04895	COG4774	siderophore transport
AT395_RS04900	COG2382	esterase
AT395_RS04920	COG5002	protein histidine kinase activity
AT395_RS04920	COG5001	Diguanylate cyclase
AT395_RS04920	COG3447	MASE1 domain protein
AT395_RS04940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AT395_RS04945	COG0840	transmembrane signaling receptor activity
AT395_RS04990	COG4106	trans-aconitate 2-methyltransferase activity
AT395_RS05010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AT395_RS05015	COG0739	heme binding
AT395_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS05045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AT395_RS05050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AT395_RS05095	COG3842	ATPase activity
AT395_RS05125	COG0589	response to stress
AT395_RS05130	COG0667	Aldo Keto reductase
AT395_RS05150	COG0457	Tetratricopeptide repeat
AT395_RS05155	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AT395_RS05160	COG1215	transferase activity, transferring glycosyl groups
AT395_RS05220	COG1012	belongs to the aldehyde dehydrogenase family
AT395_RS05235	COG0628	permease
AT395_RS05245	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AT395_RS05255	COG0784	Response regulator, receiver
AT395_RS05255	COG2205	protein histidine kinase activity
AT395_RS05260	COG2197	response regulator
AT395_RS05265	COG0730	response to heat
AT395_RS05270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AT395_RS05275	COG0598	Magnesium transport protein CorA
AT395_RS05280	COG1042	CoA-binding domain protein
AT395_RS05280	COG0045	succinate-CoA ligase (ADP-forming) activity
AT395_RS05280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AT395_RS05285	COG0783	Belongs to the Dps family
AT395_RS05330	COG0765	amino acid transport
AT395_RS05340	COG0028	Belongs to the TPP enzyme family
AT395_RS05345	COG1522	sequence-specific DNA binding
AT395_RS05355	COG1272	protein, Hemolysin III
AT395_RS05360	COG2205	protein histidine kinase activity
AT395_RS05360	COG0784	Response regulator, receiver
AT395_RS05365	COG0840	transmembrane signaling receptor activity
AT395_RS05370	COG1254	Belongs to the acylphosphatase family
AT395_RS05375	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AT395_RS05385	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AT395_RS05400	COG0084	hydrolase, TatD family'
AT395_RS05410	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AT395_RS05415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AT395_RS05435	COG2130	NADP-dependent
AT395_RS05445	COG1335	isochorismatase
AT395_RS05450	COG1024	Enoyl-CoA hydratase
AT395_RS05450	COG1250	3-hydroxyacyl-CoA dehydrogenase
AT395_RS05460	COG0411	ABC transporter
AT395_RS05470	COG0559	Belongs to the binding-protein-dependent transport system permease family
AT395_RS05475	COG0318	PFAM AMP-dependent synthetase and ligase
AT395_RS05480	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AT395_RS05485	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AT395_RS05495	COG2917	probably involved in intracellular septation
AT395_RS05505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AT395_RS05510	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AT395_RS05510	COG0047	phosphoribosylformylglycinamidine synthase activity
AT395_RS05515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AT395_RS05520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AT395_RS05520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AT395_RS05530	COG4181	ATPase activity
AT395_RS05540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AT395_RS05555	COG0776	regulation of translation
AT395_RS05560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AT395_RS05570	COG0740	serine-type endopeptidase activity
AT395_RS05575	COG0544	peptidyl-prolyl cis-trans isomerase activity
AT395_RS05585	COG1960	acyl-CoA dehydrogenase activity
AT395_RS05590	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS05605	COG0318	PFAM AMP-dependent synthetase and ligase
AT395_RS05615	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AT395_RS05625	COG0850	regulation of cytokinetic process
AT395_RS05635	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS05640	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS05645	COG0583	DNA-binding transcription factor activity
AT395_RS05660	COG2974	May be involved in recombination
AT395_RS05670	COG1132	(ABC) transporter
AT395_RS05675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AT395_RS05675	COG0189	ligase activity
AT395_RS05680	COG1181	Belongs to the D-alanine--D-alanine ligase family
AT395_RS05680	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AT395_RS05695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AT395_RS05705	COG0583	DNA-binding transcription factor activity
AT395_RS05710	COG0657	acetylesterase activity
AT395_RS05715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AT395_RS05745	COG0024	Methionine aminopeptidase
AT395_RS05770	COG1278	Cold shock
AT395_RS05790	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AT395_RS05925	COG0450	alkyl hydroperoxide reductase
AT395_RS05930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AT395_RS05935	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AT395_RS05940	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AT395_RS05945	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AT395_RS05975	COG4977	sequence-specific DNA binding
AT395_RS05980	COG0560	Phosphoserine phosphatase
AT395_RS05985	COG0626	cystathionine gamma-synthase activity
AT395_RS05990	COG0183	Belongs to the thiolase family
AT395_RS05995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AT395_RS06000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AT395_RS06010	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS06015	COG0183	Belongs to the thiolase family
AT395_RS06020	COG3243	poly(R)-hydroxyalkanoic acid synthase
AT395_RS06030	COG0564	pseudouridine synthase activity
AT395_RS06040	COG0505	Belongs to the CarA family
AT395_RS06045	COG1199	ATP-dependent helicase activity
AT395_RS06060	COG2183	response to ionizing radiation
AT395_RS06065	COG3158	transport of potassium into the cell
AT395_RS06115	COG4964	Belongs to the GSP D family
AT395_RS06160	COG1846	Transcriptional regulator
AT395_RS06190	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AT395_RS06195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AT395_RS06200	COG0508	dehydrogenase complex catalyzes the overall conversion of
AT395_RS06205	COG0567	Dehydrogenase, E1 component
AT395_RS06210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AT395_RS06215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AT395_RS06225	COG0840	transmembrane signaling receptor activity
AT395_RS06235	COG1280	lysine exporter protein (LysE YggA)
AT395_RS06265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AT395_RS06290	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AT395_RS06310	COG5001	Diguanylate cyclase
AT395_RS06310	COG4251	negative regulation of phosphorylation
AT395_RS06310	COG3706	GGDEF domain
AT395_RS06310	COG2203	Gaf domain
AT395_RS06330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AT395_RS06345	COG1177	transmembrane transport
AT395_RS06350	COG1176	ABC-type spermidine putrescine transport system, permease component I
AT395_RS06355	COG3842	ATPase activity
AT395_RS06375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AT395_RS06380	COG3706	GGDEF domain
AT395_RS06390	COG2501	S4 domain
AT395_RS06420	COG1773	rubredoxin
AT395_RS06445	COG0776	regulation of translation
AT395_RS06460	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AT395_RS06470	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AT395_RS06475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AT395_RS06485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AT395_RS06490	COG0251	oxidation-reduction process
AT395_RS06500	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS06515	COG2197	response regulator
AT395_RS06525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AT395_RS06530	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS06550	COG0477	Major facilitator Superfamily
AT395_RS06565	COG2267	carboxylic ester hydrolase activity
AT395_RS06575	COG1295	ribonuclease BN
AT395_RS06590	COG0277	FAD linked oxidase domain protein
AT395_RS06620	COG0254	rRNA binding
AT395_RS06630	COG0534	Mate efflux family protein
AT395_RS06640	COG0583	DNA-binding transcription factor activity
AT395_RS06675	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AT395_RS06680	COG0683	leucine binding
AT395_RS06690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AT395_RS06695	COG1652	LysM domain
AT395_RS06700	COG1183	phosphatidylcholine synthase activity
AT395_RS06705	COG0688	phosphatidylethanolamine metabolic process
AT395_RS06710	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AT395_RS06720	COG0028	Belongs to the TPP enzyme family
AT395_RS06725	COG1595	DNA-templated transcription, initiation
AT395_RS06755	COG0438	transferase activity, transferring glycosyl groups
AT395_RS06765	COG1309	transcriptional regulator
AT395_RS06785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AT395_RS06800	COG2346	COG2346, Truncated hemoglobins
AT395_RS06805	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AT395_RS06820	COG0745	RESPONSE REGULATOR receiver
AT395_RS06825	COG2205	protein histidine kinase activity
AT395_RS06830	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AT395_RS06835	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AT395_RS06840	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AT395_RS06850	COG0583	DNA-binding transcription factor activity
AT395_RS06875	COG3118	belongs to the thioredoxin family
AT395_RS06880	COG0475	glutathione-regulated potassium exporter activity
AT395_RS06885	COG1741	Belongs to the pirin family
AT395_RS06895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AT395_RS06910	COG1561	YicC-like family, N-terminal region
AT395_RS06920	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AT395_RS06925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AT395_RS06930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AT395_RS06960	COG2801	Transposase and inactivated derivatives
AT395_RS06985	COG3976	FMN-binding domain protein
AT395_RS06985	COG1053	succinate dehydrogenase
AT395_RS07040	COG0745	RESPONSE REGULATOR receiver
AT395_RS07090	COG1021	2,3-dihydroxybenzoate-AMP ligase
AT395_RS07160	COG3706	GGDEF domain
AT395_RS07195	COG3842	ATPase activity
AT395_RS07205	COG0583	DNA-binding transcription factor activity
AT395_RS07220	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AT395_RS07235	COG3038	cytochrome b561
AT395_RS07255	COG2223	nitrite transmembrane transporter activity
AT395_RS07270	COG1271	oxidase subunit
AT395_RS07275	COG1294	oxidase, subunit
AT395_RS07285	COG0302	gtp cyclohydrolase
AT395_RS07295	COG1131	(ABC) transporter
AT395_RS07300	COG0842	Transport permease protein
AT395_RS07310	COG0583	DNA-binding transcription factor activity
AT395_RS07325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AT395_RS07345	COG1929	Belongs to the glycerate kinase type-1 family
AT395_RS07390	COG0583	DNA-binding transcription factor activity
AT395_RS07395	COG2271	Major facilitator Superfamily
AT395_RS07405	COG0129	dihydroxy-acid dehydratase activity
AT395_RS07410	COG2084	Dehydrogenase
AT395_RS07415	COG0747	negative chemotaxis
AT395_RS07435	COG2814	Major facilitator Superfamily
AT395_RS07440	COG2814	Major facilitator Superfamily
AT395_RS07455	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AT395_RS07465	COG0583	DNA-binding transcription factor activity
AT395_RS07470	COG0427	acetyl-CoA hydrolase
AT395_RS07475	COG0840	transmembrane signaling receptor activity
AT395_RS07485	COG0840	transmembrane signaling receptor activity
AT395_RS07495	COG0252	asparaginase activity
AT395_RS07505	COG0583	DNA-binding transcription factor activity
AT395_RS07510	COG2957	Belongs to the agmatine deiminase family
AT395_RS07515	COG0697	spore germination
AT395_RS07520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT395_RS07530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AT395_RS07545	COG1610	YqeY-like protein
AT395_RS07550	COG2081	HI0933 family
AT395_RS07555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AT395_RS07560	COG1469	GTP cyclohydrolase I activity
AT395_RS07565	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AT395_RS07570	COG0142	geranyltranstransferase activity
AT395_RS07575	COG1722	exodeoxyribonuclease VII activity
AT395_RS07600	COG0412	Dienelactone hydrolase
AT395_RS07605	COG1252	NADH dehydrogenase
AT395_RS07615	COG1611	Belongs to the LOG family
AT395_RS07630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AT395_RS07640	COG0210	DNA helicase
AT395_RS07645	COG0525	valine-tRNA ligase activity
AT395_RS07655	COG0425	Belongs to the sulfur carrier protein TusA family
AT395_RS07675	COG1942	4-Oxalocrotonate Tautomerase
AT395_RS07680	COG0235	Class ii aldolase
AT395_RS07685	COG0477	Major facilitator Superfamily
AT395_RS07690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AT395_RS07695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AT395_RS07710	COG1335	isochorismatase
AT395_RS07725	COG0066	3-isopropylmalate dehydratase activity
AT395_RS07730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AT395_RS07760	COG2188	Transcriptional regulator
AT395_RS07765	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS07770	COG0583	DNA-binding transcription factor activity
AT395_RS07780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AT395_RS07790	COG1733	regulation of RNA biosynthetic process
AT395_RS07960	COG2814	Major facilitator Superfamily
AT395_RS07985	COG1522	sequence-specific DNA binding
AT395_RS07990	COG1349	DNA-binding transcription factor activity
AT395_RS08000	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS08005	COG2207	Transcriptional regulator
AT395_RS08015	COG1959	2 iron, 2 sulfur cluster binding
AT395_RS08035	COG1137	ATPase activity
AT395_RS08055	COG2368	4-hydroxyphenylacetate
AT395_RS08060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AT395_RS08065	COG1104	cysteine desulfurase activity
AT395_RS08095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AT395_RS08105	COG1301	dicarboxylic acid transport
AT395_RS08110	COG1802	Transcriptional regulator
AT395_RS08140	COG3276	selenocysteine insertion sequence binding
AT395_RS08155	COG2864	formate dehydrogenase
AT395_RS08160	COG0437	4 iron, 4 sulfur cluster binding
AT395_RS08165	COG0243	molybdopterin cofactor binding
AT395_RS08165	COG3383	formate dehydrogenase (NAD+) activity
AT395_RS08170	COG0243	molybdopterin cofactor binding
AT395_RS08170	COG3383	formate dehydrogenase (NAD+) activity
AT395_RS08180	COG2995	paraquat-inducible protein a
AT395_RS08185	COG3008	intermembrane lipid transfer
AT395_RS08215	COG3387	PFAM Glycoside hydrolase 15-related
AT395_RS08220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AT395_RS08225	COG1024	Enoyl-CoA hydratase
AT395_RS08235	COG1802	Transcriptional regulator
AT395_RS08255	COG0583	DNA-binding transcription factor activity
AT395_RS08275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AT395_RS08290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AT395_RS08300	COG4191	Histidine kinase
AT395_RS08320	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AT395_RS08330	COG1802	Transcriptional regulator
AT395_RS08335	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AT395_RS08345	COG3383	formate dehydrogenase (NAD+) activity
AT395_RS08380	COG2985	domain, Protein
AT395_RS08385	COG2985	domain, Protein
AT395_RS08395	COG0534	Mate efflux family protein
AT395_RS08415	COG0589	response to stress
AT395_RS08425	COG1175	transmembrane transport
AT395_RS08430	COG1653	transport
AT395_RS08435	COG3842	ATPase activity
AT395_RS08460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AT395_RS08470	COG0747	negative chemotaxis
AT395_RS08475	COG4172	Belongs to the ABC transporter superfamily
AT395_RS08495	COG0762	integral membrane protein
AT395_RS08500	COG1024	Enoyl-CoA hydratase
AT395_RS08505	COG1960	acyl-CoA dehydrogenase activity
AT395_RS08510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AT395_RS08525	COG2271	Major facilitator Superfamily
AT395_RS08530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS08535	COG1414	Transcriptional regulator
AT395_RS08545	COG0579	oxidoreductase
AT395_RS08560	COG2814	Major facilitator Superfamily
AT395_RS08570	COG0277	FAD linked oxidase domain protein
AT395_RS08575	COG2186	Transcriptional regulator
AT395_RS08585	COG0004	ammonium transporteR
AT395_RS08600	COG1414	Transcriptional regulator
AT395_RS08605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AT395_RS08610	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AT395_RS08635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT395_RS08640	COG1695	Transcriptional regulator
AT395_RS08645	COG2375	cellular response to nickel ion
AT395_RS08660	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS08675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AT395_RS08685	COG0028	Belongs to the TPP enzyme family
AT395_RS08685	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
AT395_RS08695	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AT395_RS08720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AT395_RS08725	COG0463	Glycosyl transferase, family 2
AT395_RS08735	COG1657	PFAM Prenyltransferase squalene oxidase
AT395_RS08740	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AT395_RS08745	COG1562	ergosterol biosynthetic process
AT395_RS08750	COG1562	ergosterol biosynthetic process
AT395_RS08760	COG2070	2-Nitropropane dioxygenase
AT395_RS08780	COG1845	cytochrome c oxidase, subunit III
AT395_RS08785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AT395_RS08790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AT395_RS08800	COG2197	response regulator
AT395_RS08805	COG5002	protein histidine kinase activity
AT395_RS08810	COG1538	Outer membrane efflux protein
AT395_RS08820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AT395_RS08825	COG2860	membrane
AT395_RS08840	COG1595	DNA-templated transcription, initiation
AT395_RS08865	COG1595	DNA-templated transcription, initiation
AT395_RS08880	COG0477	Major facilitator Superfamily
AT395_RS08890	COG0235	Class ii aldolase
AT395_RS08905	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AT395_RS08910	COG3395	kinase activity
AT395_RS08920	COG1349	DNA-binding transcription factor activity
AT395_RS08930	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AT395_RS08960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT395_RS08965	COG0583	DNA-binding transcription factor activity
AT395_RS08970	COG3284	Transcriptional regulator
AT395_RS08975	COG0667	Aldo Keto reductase
AT395_RS08990	COG1802	Transcriptional regulator
AT395_RS09000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AT395_RS09005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS09015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS09055	COG0583	DNA-binding transcription factor activity
AT395_RS09060	COG2851	Citrate transporter
AT395_RS09080	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AT395_RS09095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS09105	COG0625	glutathione transferase activity
AT395_RS09125	COG2186	Transcriptional regulator
AT395_RS09140	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AT395_RS09155	COG1414	Transcriptional regulator
AT395_RS09160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AT395_RS09165	COG3384	dioxygenase
AT395_RS09170	COG3971	2-oxopent-4-enoate hydratase activity
AT395_RS09175	COG2814	Major facilitator Superfamily
AT395_RS09180	COG2267	carboxylic ester hydrolase activity
AT395_RS09195	COG3246	L-lysine catabolic process to acetate
AT395_RS09210	COG1012	belongs to the aldehyde dehydrogenase family
AT395_RS09250	COG1024	Enoyl-CoA hydratase
AT395_RS09255	COG2030	dehydratase
AT395_RS09260	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS09265	COG0183	Belongs to the thiolase family
AT395_RS09270	COG0302	gtp cyclohydrolase
AT395_RS09280	COG0318	PFAM AMP-dependent synthetase and ligase
AT395_RS09300	COG0300	oxidoreductase activity
AT395_RS09325	COG1960	acyl-CoA dehydrogenase activity
AT395_RS09330	COG1960	acyl-CoA dehydrogenase activity
AT395_RS09335	COG1960	acyl-CoA dehydrogenase activity
AT395_RS09360	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS09365	COG0318	PFAM AMP-dependent synthetase and ligase
AT395_RS09390	COG0179	Fumarylacetoacetate (FAA) hydrolase
AT395_RS09400	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS09415	COG1309	transcriptional regulator
AT395_RS09450	COG2801	Transposase and inactivated derivatives
AT395_RS09455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AT395_RS09485	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AT395_RS09490	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AT395_RS09495	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AT395_RS09500	COG1674	ftsk spoiiie
AT395_RS09505	COG0492	ferredoxin-NADP+ reductase activity
AT395_RS09510	COG1193	negative regulation of DNA recombination
AT395_RS09515	COG2860	membrane
AT395_RS09535	COG2249	NAD(P)H dehydrogenase (quinone) activity
AT395_RS09545	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AT395_RS09560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AT395_RS09565	COG1176	ABC-type spermidine putrescine transport system, permease component I
AT395_RS09580	COG0277	FAD linked oxidase domain protein
AT395_RS09595	COG2271	Major facilitator Superfamily
AT395_RS09600	COG0477	Major facilitator Superfamily
AT395_RS09625	COG0181	hydroxymethylbilane synthase activity
AT395_RS09640	COG0165	Argininosuccinate lyase
AT395_RS09645	COG0786	glutamate:sodium symporter activity
AT395_RS09655	COG0717	Belongs to the dCTP deaminase family
AT395_RS09660	COG0489	protein tyrosine kinase activity
AT395_RS09665	COG2885	chlorophyll binding
AT395_RS09675	COG2226	methyltransferase
AT395_RS09680	COG1522	sequence-specific DNA binding
AT395_RS09695	COG2911	Protein conserved in bacteria
AT395_RS09715	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AT395_RS09720	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AT395_RS09725	COG0489	protein tyrosine kinase activity
AT395_RS09730	COG1492	cobalamin metabolic process
AT395_RS09755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AT395_RS09765	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AT395_RS09770	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AT395_RS09780	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AT395_RS09785	COG4139	cobalamin transport
AT395_RS09790	COG4206	TonB-dependent receptor
AT395_RS09805	COG1960	acyl-CoA dehydrogenase activity
AT395_RS09830	COG1024	Enoyl-CoA hydratase
AT395_RS09840	COG2951	lytic endotransglycosylase activity
AT395_RS09855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AT395_RS09860	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AT395_RS09870	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AT395_RS09880	COG0776	regulation of translation
AT395_RS09890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AT395_RS09900	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AT395_RS09905	COG0287	Prephenate dehydrogenase
AT395_RS09915	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AT395_RS09950	COG0318	PFAM AMP-dependent synthetase and ligase
AT395_RS09955	COG1024	Enoyl-CoA hydratase
AT395_RS09975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AT395_RS09980	COG1802	Transcriptional regulator
AT395_RS09985	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AT395_RS09990	COG0583	DNA-binding transcription factor activity
AT395_RS09995	COG0129	dihydroxy-acid dehydratase activity
AT395_RS10010	COG1566	PFAM secretion protein HlyD family protein
AT395_RS10015	COG1289	transmembrane transporter activity
AT395_RS10040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AT395_RS10045	COG0795	lipopolysaccharide-transporting ATPase activity
AT395_RS10050	COG0795	lipopolysaccharide-transporting ATPase activity
AT395_RS10060	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AT395_RS10060	COG1648	precorrin-2 dehydrogenase activity
AT395_RS10065	COG2895	sulfate adenylyltransferase (ATP) activity
AT395_RS10075	COG0175	sulfate reduction
AT395_RS10080	COG0730	response to heat
AT395_RS10085	COG0583	DNA-binding transcription factor activity
AT395_RS10095	COG2084	Dehydrogenase
AT395_RS10105	COG3246	L-lysine catabolic process to acetate
AT395_RS10115	COG2271	Major facilitator Superfamily
AT395_RS10135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AT395_RS10160	COG0386	Belongs to the glutathione peroxidase family
AT395_RS10195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AT395_RS10200	COG1012	belongs to the aldehyde dehydrogenase family
AT395_RS10210	COG0028	Belongs to the TPP enzyme family
AT395_RS10220	COG1414	Transcriptional regulator
AT395_RS10240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS10255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AT395_RS10275	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AT395_RS10285	COG0640	Transcriptional regulator
AT395_RS10295	COG2814	Major facilitator Superfamily
AT395_RS10300	COG0443	Heat shock 70 kDa protein
AT395_RS10310	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AT395_RS10315	COG3360	Dodecin
AT395_RS10325	COG0837	glucose binding
AT395_RS10325	COG1737	Transcriptional regulator
AT395_RS10335	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AT395_RS10350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AT395_RS10360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AT395_RS10365	COG0671	phosphoesterase, PA-phosphatase related
AT395_RS10370	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AT395_RS10375	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AT395_RS10380	COG1704	LemA family
AT395_RS10395	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AT395_RS10395	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AT395_RS10405	COG3971	2-oxopent-4-enoate hydratase activity
AT395_RS10450	COG0640	Transcriptional regulator
AT395_RS10460	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AT395_RS10465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AT395_RS10470	COG0436	Aminotransferase
AT395_RS10480	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AT395_RS10490	COG0531	amino acid
AT395_RS10495	COG5001	Diguanylate cyclase
AT395_RS10495	COG3300	MHYT domain
AT395_RS10505	COG2011	ABC-type metal ion transport system permease component
AT395_RS10510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AT395_RS10515	COG2201	protein-glutamate methylesterase activity
AT395_RS10530	COG4585	Histidine kinase
AT395_RS10535	COG3237	CsbD-like
AT395_RS10585	COG0745	RESPONSE REGULATOR receiver
AT395_RS10590	COG2205	protein histidine kinase activity
AT395_RS10595	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS10600	COG3842	ATPase activity
AT395_RS10610	COG4149	molybdate abc transporter
AT395_RS10635	COG1987	bacterial-type flagellum assembly
AT395_RS10690	COG4786	Flagellar basal body rod
AT395_RS10735	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AT395_RS10740	COG1191	sigma factor activity
AT395_RS10790	COG3634	alkyl hydroperoxide reductase activity
AT395_RS10810	COG1288	antiporter activity
AT395_RS10825	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS10845	COG2814	Major facilitator Superfamily
AT395_RS10855	COG1917	Cupin 2, conserved barrel domain protein
AT395_RS10855	COG2207	Transcriptional regulator
AT395_RS10860	COG0596	Alpha beta hydrolase
AT395_RS10865	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AT395_RS10875	COG3485	protocatechuate 3,4-dioxygenase
AT395_RS10880	COG3485	protocatechuate 3,4-dioxygenase
AT395_RS10885	COG0583	DNA-binding transcription factor activity
AT395_RS10895	COG1960	acyl-CoA dehydrogenase activity
AT395_RS10900	COG0318	PFAM AMP-dependent synthetase and ligase
AT395_RS10905	COG1012	belongs to the aldehyde dehydrogenase family
AT395_RS10910	COG1024	Enoyl-CoA hydratase
AT395_RS10915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS10920	COG2814	Major facilitator Superfamily
AT395_RS10945	COG0840	transmembrane signaling receptor activity
AT395_RS10950	COG0643	Histidine kinase
AT395_RS10950	COG2198	Histidine kinase
AT395_RS10955	COG0583	DNA-binding transcription factor activity
AT395_RS10965	COG2814	Major facilitator Superfamily
AT395_RS10975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AT395_RS10980	COG0601	transmembrane transport
AT395_RS10985	COG0747	negative chemotaxis
AT395_RS10990	COG4608	Belongs to the ABC transporter superfamily
AT395_RS10995	COG0444	Belongs to the ABC transporter superfamily
AT395_RS11005	COG0477	Major facilitator Superfamily
AT395_RS11010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AT395_RS11015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AT395_RS11020	COG1845	cytochrome c oxidase, subunit III
AT395_RS11025	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AT395_RS11035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT395_RS11050	COG2011	ABC-type metal ion transport system permease component
AT395_RS11055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AT395_RS11060	COG1464	Belongs to the NlpA lipoprotein family
AT395_RS11065	COG1686	Belongs to the peptidase S11 family
AT395_RS11070	COG0477	Major facilitator Superfamily
AT395_RS11075	COG1297	OPT oligopeptide transporter protein
AT395_RS11150	COG0811	peptide transport
AT395_RS11165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AT395_RS11170	COG4566	intracellular signal transduction
AT395_RS11180	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AT395_RS11210	COG3938	Belongs to the proline racemase family
AT395_RS11215	COG0395	ABC-type sugar transport system, permease component
AT395_RS11225	COG3842	ATPase activity
AT395_RS11245	COG0583	DNA-binding transcription factor activity
AT395_RS11260	COG4948	Mandelate Racemase Muconate Lactonizing
AT395_RS11270	COG0583	DNA-binding transcription factor activity
AT395_RS11275	COG1129	ABC transporter
AT395_RS11280	COG1172	Belongs to the binding-protein-dependent transport system permease family
AT395_RS11285	COG1172	Belongs to the binding-protein-dependent transport system permease family
AT395_RS11290	COG1879	ABC-type sugar transport system periplasmic component
AT395_RS11300	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AT395_RS11305	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS11310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AT395_RS11315	COG0154	amidase activity
AT395_RS11345	COG3179	chitinase
AT395_RS11420	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AT395_RS11430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AT395_RS11455	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AT395_RS11480	COG1741	Belongs to the pirin family
AT395_RS11500	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AT395_RS11510	COG0783	Belongs to the Dps family
AT395_RS11515	COG0352	thiamine-phosphate diphosphorylase activity
AT395_RS11520	COG0753	catalase activity
AT395_RS11530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AT395_RS11540	COG0343	queuine tRNA-ribosyltransferase activity
AT395_RS11545	COG1862	Preprotein translocase
AT395_RS11550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AT395_RS11565	COG3909	cytochrome
AT395_RS11580	COG0741	lytic transglycosylase activity
AT395_RS11635	COG2197	response regulator
AT395_RS11700	COG2207	Transcriptional regulator
AT395_RS11705	COG0069	glutamate synthase activity
AT395_RS11710	COG0482	sulfurtransferase activity
AT395_RS11735	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AT395_RS11750	COG3265	gluconokinase activity
AT395_RS11760	COG0800	Aldolase
AT395_RS11770	COG1737	Transcriptional regulator
AT395_RS11775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AT395_RS11785	COG1981	membrane
AT395_RS11790	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AT395_RS11795	COG2255	four-way junction helicase activity
AT395_RS11805	COG0406	alpha-ribazole phosphatase activity
AT395_RS11810	COG1881	PFAM PEBP family protein
AT395_RS11825	COG0739	heme binding
AT395_RS11830	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AT395_RS11835	COG0316	Belongs to the HesB IscA family
AT395_RS11840	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AT395_RS11845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AT395_RS11850	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AT395_RS11865	COG0418	dihydroorotase activity
AT395_RS11870	COG0121	glutamine amidotransferase
AT395_RS11875	COG1126	abc transporter atp-binding protein
AT395_RS11880	COG0765	amino acid transport
AT395_RS11885	COG0765	amino acid transport
AT395_RS11895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AT395_RS11905	COG5265	(ABC) transporter
AT395_RS11920	COG0183	Belongs to the thiolase family
AT395_RS11925	COG1024	Enoyl-CoA hydratase
AT395_RS11925	COG1250	3-hydroxyacyl-CoA dehydrogenase
AT395_RS11930	COG1960	acyl-CoA dehydrogenase activity
AT395_RS11940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AT395_RS11945	COG0494	nUDIX hydrolase
AT395_RS11950	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AT395_RS11970	COG0500	methyltransferase
AT395_RS11975	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AT395_RS11990	COG2226	methyltransferase
AT395_RS12005	COG0025	NhaP-type Na H and K H
AT395_RS12025	COG1238	metal cluster binding
AT395_RS12035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AT395_RS12045	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AT395_RS12045	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AT395_RS12070	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AT395_RS12090	COG0477	Major facilitator Superfamily
AT395_RS12095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AT395_RS12170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AT395_RS12175	COG2271	Major facilitator Superfamily
AT395_RS12225	COG5001	Diguanylate cyclase
AT395_RS12230	COG0625	glutathione transferase activity
AT395_RS12235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT395_RS12240	COG4521	taurine ABC transporter
AT395_RS12245	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AT395_RS12250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS12255	COG1113	amino acid transport
AT395_RS12265	COG1228	amidohydrolase
AT395_RS12270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AT395_RS12300	COG0730	response to heat
AT395_RS12315	COG1414	Transcriptional regulator
AT395_RS12320	COG1414	Transcriptional regulator
AT395_RS12345	COG1902	pentaerythritol trinitrate reductase activity
AT395_RS12350	COG0583	DNA-binding transcription factor activity
AT395_RS12355	COG0047	phosphoribosylformylglycinamidine synthase activity
AT395_RS12370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AT395_RS12375	COG0473	3-isopropylmalate dehydrogenase activity
AT395_RS12380	COG0583	DNA-binding transcription factor activity
AT395_RS12395	COG2814	Major facilitator Superfamily
AT395_RS12445	COG1414	Transcriptional regulator
AT395_RS12455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AT395_RS12465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AT395_RS12485	COG1448	Aminotransferase
AT395_RS12495	COG0625	glutathione transferase activity
AT395_RS12510	COG0583	DNA-binding transcription factor activity
AT395_RS12520	COG2186	Transcriptional regulator
AT395_RS12525	COG1620	l-lactate permease
AT395_RS12530	COG0247	lactate metabolic process
AT395_RS12535	COG1139	Iron-sulfur cluster binding protein
AT395_RS12545	COG3047	cAMP biosynthetic process
AT395_RS12555	COG4771	TonB-dependent receptor
AT395_RS12560	COG3038	cytochrome b561
AT395_RS12565	COG0656	L-ascorbic acid biosynthetic process
AT395_RS12570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AT395_RS12575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AT395_RS12580	COG1733	regulation of RNA biosynthetic process
AT395_RS12590	COG2610	gluconate transmembrane transporter activity
AT395_RS12660	COG1126	abc transporter atp-binding protein
AT395_RS12665	COG0010	Belongs to the arginase family
AT395_RS12670	COG0765	amino acid transport
AT395_RS12700	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS12700	COG3321	synthase
AT395_RS12700	COG0604	alcohol dehydrogenase
AT395_RS12720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AT395_RS12725	COG0318	PFAM AMP-dependent synthetase and ligase
AT395_RS12735	COG4172	Belongs to the ABC transporter superfamily
AT395_RS12745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AT395_RS12750	COG0477	Major facilitator Superfamily
AT395_RS12760	COG0583	DNA-binding transcription factor activity
AT395_RS12765	COG0632	four-way junction helicase activity
AT395_RS12785	COG0625	glutathione transferase activity
AT395_RS12790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AT395_RS12795	COG2271	Major facilitator Superfamily
AT395_RS12800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AT395_RS12825	COG2207	Transcriptional regulator
AT395_RS12830	COG0667	Aldo Keto reductase
AT395_RS12835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS12865	COG0625	glutathione transferase activity
AT395_RS12895	COG1012	belongs to the aldehyde dehydrogenase family
AT395_RS12900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT395_RS12910	COG1802	Transcriptional regulator
AT395_RS12915	COG1473	amidohydrolase
AT395_RS12920	COG1418	mRNA catabolic process
AT395_RS12925	COG0629	single-stranded DNA binding
AT395_RS12930	COG2814	Major facilitator Superfamily
AT395_RS12955	COG0251	oxidation-reduction process
AT395_RS12970	COG1283	sodium-dependent phosphate transmembrane transporter activity
AT395_RS12975	COG1012	belongs to the aldehyde dehydrogenase family
AT395_RS12990	COG1840	ABC-type Fe3 transport system, periplasmic component
AT395_RS12995	COG3842	ATPase activity
AT395_RS13005	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AT395_RS13015	COG0477	Major facilitator Superfamily
AT395_RS13040	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AT395_RS13045	COG2188	Transcriptional regulator
AT395_RS13050	COG3624	Phosphonate C-P lyase system protein PhnG
AT395_RS13055	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AT395_RS13060	COG3626	phosphonate metabolism
AT395_RS13065	COG3627	carbon phosphorus lyase activity
AT395_RS13070	COG4107	phosphonate C-P lyase system protein PhnK
AT395_RS13075	COG4778	phosphonate C-P lyase system protein PhnL
AT395_RS13080	COG3454	Phosphonate metabolism
AT395_RS13085	COG3639	organic phosphonate transmembrane transporter activity
AT395_RS13090	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AT395_RS13095	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AT395_RS13105	COG1280	lysine exporter protein (LysE YggA)
AT395_RS13110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AT395_RS13125	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AT395_RS13140	COG1137	ATPase activity
AT395_RS13145	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AT395_RS13150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AT395_RS13160	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AT395_RS13170	COG1660	Displays ATPase and GTPase activities
AT395_RS13175	COG1194	a g-specific adenine glycosylase
AT395_RS13180	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AT395_RS13190	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AT395_RS13205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AT395_RS13215	COG0193	aminoacyl-tRNA hydrolase activity
AT395_RS13220	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AT395_RS13225	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AT395_RS13230	COG0742	ribosomal rna small subunit methyltransferase
AT395_RS13235	COG1131	(ABC) transporter
AT395_RS13245	COG0612	Peptidase, M16
AT395_RS13250	COG0612	Peptidase, M16
AT395_RS13265	COG0625	glutathione transferase activity
AT395_RS13270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AT395_RS13280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AT395_RS13295	COG1294	oxidase, subunit
AT395_RS13300	COG1999	signal sequence binding
AT395_RS13310	COG1612	heme a metabolic process
AT395_RS13340	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AT395_RS13345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AT395_RS13360	COG2771	luxR family
AT395_RS13365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AT395_RS13375	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AT395_RS13380	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AT395_RS13390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AT395_RS13395	COG2423	ornithine cyclodeaminase activity
AT395_RS13400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AT395_RS13405	COG2226	methyltransferase
AT395_RS13410	COG1040	competence protein
AT395_RS13420	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AT395_RS13430	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AT395_RS13435	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AT395_RS13440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AT395_RS13450	COG0793	Belongs to the peptidase S41A family
AT395_RS13455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AT395_RS13460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AT395_RS13465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AT395_RS13475	COG0189	ligase activity
AT395_RS13490	COG0004	ammonium transporteR
AT395_RS13495	COG0347	Belongs to the P(II) protein family
AT395_RS13505	COG2960	long-chain fatty acid transporting porin activity
AT395_RS13510	COG0606	chelatase, subunit chli
AT395_RS13530	COG2204	response regulator
AT395_RS13535	COG4191	Histidine kinase
AT395_RS13545	COG1116	anion transmembrane transporter activity
AT395_RS13550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS13575	COG0321	lipoyl(octanoyl) transferase activity
AT395_RS13590	COG0583	DNA-binding transcription factor activity
AT395_RS13595	COG2921	Belongs to the UPF0250 family
AT395_RS13600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AT395_RS13605	COG1686	Belongs to the peptidase S11 family
AT395_RS13620	COG0477	Major facilitator Superfamily
AT395_RS13640	COG1127	ABC transporter
AT395_RS13645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AT395_RS13670	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AT395_RS13710	COG1024	Enoyl-CoA hydratase
AT395_RS13735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AT395_RS13755	COG0646	methionine synthase
AT395_RS13755	COG1410	methionine synthase
AT395_RS13775	COG0018	arginyl-trna synthetase
AT395_RS13785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AT395_RS13805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AT395_RS13810	COG0789	Transcriptional regulator
AT395_RS13820	COG1960	acyl-CoA dehydrogenase activity
AT395_RS13825	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AT395_RS13830	COG0288	reversible hydration of carbon dioxide
AT395_RS13835	COG0183	Belongs to the thiolase family
AT395_RS13840	COG0300	oxidoreductase activity
AT395_RS13850	COG3012	SEC-C Motif Domain Protein
AT395_RS13855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AT395_RS13860	COG1024	Enoyl-CoA hydratase
AT395_RS13870	COG0156	8-amino-7-oxononanoate synthase activity
AT395_RS13875	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AT395_RS13880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AT395_RS13885	COG4770	biotin carboxylase activity
AT395_RS13895	COG2207	Transcriptional regulator
AT395_RS13905	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS13920	COG3706	GGDEF domain
AT395_RS13925	COG0697	spore germination
AT395_RS13945	COG4681	YaeQ
AT395_RS13950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AT395_RS13995	COG1250	3-hydroxyacyl-CoA dehydrogenase
AT395_RS14040	COG2132	Multicopper oxidase
AT395_RS14050	COG1739	Uncharacterized protein family UPF0029
AT395_RS14060	COG1741	Belongs to the pirin family
AT395_RS14090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AT395_RS14090	COG2169	Transcriptional regulator
AT395_RS14115	COG0583	DNA-binding transcription factor activity
AT395_RS14130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AT395_RS14160	COG0583	DNA-binding transcription factor activity
AT395_RS14165	COG0625	glutathione transferase activity
AT395_RS14180	COG0583	DNA-binding transcription factor activity
AT395_RS14230	COG0038	chloride channel
AT395_RS14245	COG0642	Histidine kinase
AT395_RS14265	COG3842	ATPase activity
AT395_RS14270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS14280	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS14285	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AT395_RS14295	COG3048	D-serine ammonia-lyase activity
AT395_RS14300	COG2271	Major facilitator Superfamily
AT395_RS14310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AT395_RS14360	COG0625	glutathione transferase activity
AT395_RS14380	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AT395_RS14385	COG1984	allophanate hydrolase subunit 2
AT395_RS14390	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AT395_RS14395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AT395_RS14400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT395_RS14415	COG2814	Major facilitator Superfamily
AT395_RS14455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT395_RS14460	COG0765	amino acid transport
AT395_RS14465	COG0765	amino acid transport
AT395_RS14470	COG1126	abc transporter atp-binding protein
AT395_RS14475	COG0831	urea catabolic process
AT395_RS14485	COG0832	Belongs to the urease beta subunit family
AT395_RS14490	COG0804	urea catabolic process
AT395_RS14500	COG0830	nickel cation binding
AT395_RS14505	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AT395_RS14515	COG4608	Belongs to the ABC transporter superfamily
AT395_RS14520	COG0444	Belongs to the ABC transporter superfamily
AT395_RS14525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AT395_RS14530	COG0601	transmembrane transport
AT395_RS14535	COG0747	negative chemotaxis
AT395_RS14540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AT395_RS14545	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AT395_RS14550	COG1950	PFAM Membrane protein of
AT395_RS14555	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AT395_RS14560	COG1346	cytolysis
AT395_RS14565	COG1380	Effector of murein hydrolase LrgA
AT395_RS14570	COG0583	DNA-binding transcription factor activity
AT395_RS14575	COG0708	Exodeoxyribonuclease III
AT395_RS14585	COG2814	Major facilitator Superfamily
AT395_RS14590	COG2813	Specifically methylates the guanine in position
AT395_RS14590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AT395_RS14595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AT395_RS14600	COG1309	transcriptional regulator
AT395_RS14610	COG2814	Major facilitator Superfamily
AT395_RS14615	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS14630	COG2828	Protein conserved in bacteria
AT395_RS14635	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AT395_RS14640	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AT395_RS14645	COG0410	ABC transporter
AT395_RS14665	COG0683	leucine binding
AT395_RS14675	COG3384	dioxygenase
AT395_RS14685	COG2188	Transcriptional regulator
AT395_RS14700	COG0477	Major facilitator Superfamily
AT395_RS14725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AT395_RS14745	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AT395_RS14755	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AT395_RS14760	COG4206	TonB-dependent receptor
AT395_RS14775	COG0523	cobalamin synthesis protein
AT395_RS14790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AT395_RS14795	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AT395_RS14805	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AT395_RS14810	COG1560	Kdo2-lipid A biosynthetic process
AT395_RS14815	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AT395_RS14825	COG1960	acyl-CoA dehydrogenase activity
AT395_RS14845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AT395_RS14880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AT395_RS14885	COG2326	polyphosphate kinase activity
AT395_RS14890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AT395_RS14905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AT395_RS14910	COG1077	Cell shape determining protein MreB Mrl
AT395_RS14915	COG1792	Involved in formation and maintenance of cell shape
AT395_RS14925	COG0768	penicillin binding
AT395_RS14930	COG0772	Belongs to the SEDS family
AT395_RS14945	COG0720	synthase
AT395_RS14950	COG0602	queuosine metabolic process
AT395_RS14965	COG2204	response regulator
AT395_RS14965	COG2204	response regulator
AT395_RS14970	COG5000	phosphorelay sensor kinase activity
AT395_RS14980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AT395_RS14980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AT395_RS14985	COG0501	Belongs to the peptidase M48B family
AT395_RS15000	COG0242	peptide deformylase activity
AT395_RS15005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AT395_RS15005	COG0758	DNA mediated transformation
AT395_RS15020	COG0583	DNA-binding transcription factor activity
AT395_RS15030	COG2879	small protein
AT395_RS15035	COG1966	Carbon starvation protein
AT395_RS15055	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AT395_RS15060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AT395_RS15090	COG3128	pkhd-type hydroxylase
AT395_RS15095	COG4774	siderophore transport
AT395_RS15100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AT395_RS15105	COG1672	PFAM Archaeal ATPase
AT395_RS15105	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AT395_RS15115	COG2957	Belongs to the agmatine deiminase family
AT395_RS15120	COG1802	Transcriptional regulator
AT395_RS15165	COG1473	amidohydrolase
AT395_RS15190	COG2203	Gaf domain
AT395_RS15190	COG5001	Diguanylate cyclase
AT395_RS15190	COG3706	GGDEF domain
AT395_RS15190	COG4251	negative regulation of phosphorylation
AT395_RS15195	COG2201	protein-glutamate methylesterase activity
AT395_RS15205	COG0835	chemotaxis
AT395_RS15210	COG0457	Tetratricopeptide repeat
AT395_RS15210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AT395_RS15220	COG0840	transmembrane signaling receptor activity
AT395_RS15230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AT395_RS15245	COG2223	nitrite transmembrane transporter activity
AT395_RS15250	COG2771	luxR family
AT395_RS15250	COG2200	EAL domain
AT395_RS15265	COG2814	Major facilitator Superfamily
AT395_RS15270	COG0583	DNA-binding transcription factor activity
AT395_RS15280	COG0583	DNA-binding transcription factor activity
AT395_RS15315	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AT395_RS15320	COG2733	membrane
AT395_RS15335	COG0583	DNA-binding transcription factor activity
AT395_RS15340	COG2252	PERMEase
AT395_RS15365	COG0583	DNA-binding transcription factor activity
AT395_RS15370	COG1968	undecaprenyl-diphosphatase activity
AT395_RS15390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AT395_RS15400	COG3712	iron ion homeostasis
AT395_RS15405	COG4774	siderophore transport
AT395_RS15425	COG1309	transcriptional regulator
AT395_RS15430	COG1252	NADH dehydrogenase
AT395_RS15470	COG0765	amino acid transport
AT395_RS15475	COG0765	amino acid transport
AT395_RS15480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT395_RS15485	COG0583	DNA-binding transcription factor activity
AT395_RS15495	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AT395_RS15515	COG1131	(ABC) transporter
AT395_RS15525	COG0477	Major facilitator Superfamily
AT395_RS15530	COG0840	transmembrane signaling receptor activity
AT395_RS15590	COG1802	Transcriptional regulator
AT395_RS15595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AT395_RS15600	COG0477	Major facilitator Superfamily
AT395_RS15610	COG3829	transcription factor binding
AT395_RS15615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AT395_RS15625	COG0583	DNA-binding transcription factor activity
AT395_RS15630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AT395_RS15635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AT395_RS15640	COG1396	sequence-specific DNA binding
AT395_RS15665	COG0833	amino acid
AT395_RS15670	COG1414	Transcriptional regulator
AT395_RS15690	COG1137	ATPase activity
AT395_RS15695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AT395_RS15710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AT395_RS15720	COG0594	ribonuclease P activity
AT395_RS15725	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AT395_RS15730	COG0706	membrane insertase activity
AT395_RS15765	COG5001	Diguanylate cyclase
AT395_RS15765	COG3300	MHYT domain
AT395_RS15770	COG2814	Major facilitator Superfamily
AT395_RS15780	COG1846	Transcriptional regulator
AT395_RS15785	COG0038	chloride channel
AT395_RS15790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AT395_RS15790	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AT395_RS15815	COG2154	pterin-4-alpha-carbinolamine dehydratase
AT395_RS15820	COG3186	Phenylalanine-4-hydroxylase
AT395_RS15825	COG1522	sequence-specific DNA binding
AT395_RS15845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AT395_RS15850	COG2423	ornithine cyclodeaminase activity
AT395_RS15860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AT395_RS15865	COG4558	Periplasmic binding protein
AT395_RS15870	COG3720	iron ion transport
AT395_RS15875	COG4771	TonB-dependent receptor
AT395_RS15880	COG1522	sequence-specific DNA binding
AT395_RS15925	COG0583	DNA-binding transcription factor activity
AT395_RS15985	COG1846	Transcriptional regulator
AT395_RS16010	COG0445	tRNA wobble uridine modification
AT395_RS16015	COG0357	Ribosomal RNA small subunit methyltransferase G
AT395_RS16020	COG3040	lipid binding
AT395_RS16025	COG1192	Involved in chromosome partitioning
AT395_RS16030	COG1475	DNA binding
AT395_RS16035	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AT395_RS16045	COG0356	it plays a direct role in the translocation of protons across the membrane
AT395_RS16055	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AT395_RS16070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AT395_RS16075	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AT395_RS16080	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AT395_RS16085	COG0318	PFAM AMP-dependent synthetase and ligase
AT395_RS16090	COG2814	Major facilitator Superfamily
AT395_RS16110	COG1360	Flagellar Motor Protein
AT395_RS16115	COG0784	Response regulator, receiver
AT395_RS16115	COG2205	protein histidine kinase activity
AT395_RS16115	COG2198	Histidine kinase
AT395_RS16120	COG0643	Histidine kinase
AT395_RS16120	COG2198	Histidine kinase
AT395_RS16125	COG0835	chemotaxis
AT395_RS16130	COG0840	transmembrane signaling receptor activity
AT395_RS16135	COG0840	transmembrane signaling receptor activity
AT395_RS16140	COG0840	transmembrane signaling receptor activity
AT395_RS16145	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AT395_RS16150	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AT395_RS16160	COG0745	RESPONSE REGULATOR receiver
AT395_RS16165	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AT395_RS16175	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AT395_RS16190	COG1191	sigma factor activity
AT395_RS16210	COG1815	bacterial-type flagellum-dependent cell motility
AT395_RS16215	COG1558	bacterial-type flagellum-dependent cell motility
AT395_RS16230	COG4787	bacterial-type flagellum-dependent cell motility
AT395_RS16240	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AT395_RS16245	COG1706	bacterial-type flagellum-dependent cell motility
AT395_RS16255	COG1256	bacterial-type flagellum assembly
AT395_RS16275	COG1338	Plays a role in the flagellum-specific transport system
AT395_RS16295	COG1580	Controls the rotational direction of flagella during chemotaxis
AT395_RS16315	COG1317	bacterial-type flagellum organization
AT395_RS16335	COG2257	FlhB HrpN YscU SpaS Family
AT395_RS16355	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AT395_RS16365	COG2197	response regulator
AT395_RS16370	COG3851	Histidine kinase
AT395_RS16380	COG0745	RESPONSE REGULATOR receiver
AT395_RS16385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AT395_RS16395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS16410	COG0745	RESPONSE REGULATOR receiver
AT395_RS16415	COG2205	protein histidine kinase activity
AT395_RS16420	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AT395_RS16435	COG3245	cytochrome
AT395_RS16445	COG0210	DNA helicase
AT395_RS16460	COG0509	glycine decarboxylation via glycine cleavage system
AT395_RS16470	COG1760	l-serine dehydratase
AT395_RS16480	COG1115	amino acid carrier protein
AT395_RS16500	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AT395_RS16500	COG0506	proline dehydrogenase activity
AT395_RS16500	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AT395_RS16515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AT395_RS16520	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AT395_RS16530	COG0657	acetylesterase activity
AT395_RS16535	COG1832	CoA-binding protein
AT395_RS16540	COG3622	Belongs to the hyi family
AT395_RS16565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AT395_RS16585	COG1122	ATPase activity
AT395_RS16595	COG0792	nuclease activity
AT395_RS16600	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AT395_RS16605	COG2823	Periplasmic or secreted lipoprotein
AT395_RS16615	COG0446	pyridine nucleotide-disulphide oxidoreductase
AT395_RS16630	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AT395_RS16635	COG4654	Cytochrome c, class I
AT395_RS16640	COG4654	Cytochrome c, class I
AT395_RS16660	COG2010	Cytochrome c
AT395_RS16670	COG0737	Belongs to the 5'-nucleotidase family
AT395_RS16685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AT395_RS16685	COG0543	2 iron, 2 sulfur cluster binding
AT395_RS16690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AT395_RS16710	COG2244	polysaccharide biosynthetic process
AT395_RS16715	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AT395_RS16760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AT395_RS16765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AT395_RS16770	COG1845	cytochrome c oxidase, subunit III
AT395_RS16775	COG1845	cytochrome c oxidase, subunit III
AT395_RS16790	COG4336	lyase activity
AT395_RS16795	COG2814	Major facilitator Superfamily
AT395_RS16840	COG2827	Endonuclease containing a URI domain
AT395_RS16845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AT395_RS16860	COG2233	PERMEase
AT395_RS16865	COG0583	DNA-binding transcription factor activity
AT395_RS16870	COG0513	Belongs to the DEAD box helicase family
AT395_RS16890	COG2226	methyltransferase
AT395_RS16900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AT395_RS16905	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AT395_RS16910	COG2814	Major facilitator Superfamily
AT395_RS16930	COG1522	sequence-specific DNA binding
AT395_RS16950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AT395_RS16955	COG2151	metal-sulfur cluster biosynthetic enzyme
AT395_RS16960	COG3396	Phenylacetate-CoA oxygenase
AT395_RS16965	COG3460	Phenylacetate-CoA oxygenase
AT395_RS16970	COG3396	Phenylacetate-CoA oxygenase
AT395_RS16985	COG1595	DNA-templated transcription, initiation
AT395_RS16990	COG3712	iron ion homeostasis
AT395_RS16995	COG4774	siderophore transport
AT395_RS17010	COG0156	8-amino-7-oxononanoate synthase activity
AT395_RS17015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AT395_RS17020	COG0242	peptide deformylase activity
AT395_RS17030	COG1522	sequence-specific DNA binding
AT395_RS17040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AT395_RS17100	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AT395_RS17110	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AT395_RS17120	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AT395_RS17125	COG0222	ribosome binding
AT395_RS17140	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AT395_RS17140	COG0662	Cupin 2, conserved barrel domain protein
AT395_RS17145	COG4772	TonB-dependent receptor
AT395_RS17150	COG3971	2-oxopent-4-enoate hydratase activity
AT395_RS17160	COG1012	belongs to the aldehyde dehydrogenase family
AT395_RS17170	COG0179	Fumarylacetoacetate (FAA) hydrolase
AT395_RS17175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AT395_RS17185	COG1448	Aminotransferase
AT395_RS17190	COG0583	DNA-binding transcription factor activity
AT395_RS17220	COG2207	Transcriptional regulator
AT395_RS17235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT395_RS17240	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AT395_RS17245	COG0049	tRNA binding
AT395_RS17255	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AT395_RS17260	COG0051	transcription antitermination factor activity, RNA binding
AT395_RS17265	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AT395_RS17270	COG0088	Forms part of the polypeptide exit tunnel
AT395_RS17275	COG0089	rRNA binding
AT395_RS17280	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AT395_RS17285	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AT395_RS17290	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AT395_RS17295	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AT395_RS17305	COG0255	Belongs to the universal ribosomal protein uL29 family
AT395_RS17310	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AT395_RS17315	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AT395_RS17320	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AT395_RS17325	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AT395_RS17330	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AT395_RS17340	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AT395_RS17345	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AT395_RS17360	COG0200	Binds to the 23S rRNA
AT395_RS17365	COG0201	protein transport
AT395_RS17370	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AT395_RS17375	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AT395_RS17380	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AT395_RS17385	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AT395_RS17390	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AT395_RS17395	COG0202	RNA polymerase activity
AT395_RS17400	COG0203	ribosomal protein L17
AT395_RS17410	COG4232	protein-disulfide reductase activity
AT395_RS17420	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AT395_RS17430	COG1333	cytochrome c biogenesis protein
AT395_RS17435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AT395_RS17440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AT395_RS17445	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AT395_RS17450	COG0019	diaminopimelate decarboxylase activity
AT395_RS17455	COG1965	Belongs to the frataxin family
AT395_RS17485	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AT395_RS17490	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AT395_RS17500	COG3047	cAMP biosynthetic process
AT395_RS17505	COG3047	cAMP biosynthetic process
AT395_RS17515	COG0070	glutamate synthase
AT395_RS17515	COG0069	glutamate synthase activity
AT395_RS17515	COG0067	glutamate synthase
AT395_RS17525	COG2271	Major facilitator Superfamily
AT395_RS17530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AT395_RS17540	COG2814	Major facilitator Superfamily
AT395_RS17545	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS17550	COG4178	(ABC) transporter
AT395_RS17570	COG0352	thiamine-phosphate diphosphorylase activity
AT395_RS17580	COG1127	ABC transporter
AT395_RS17585	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AT395_RS17590	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AT395_RS17610	COG1131	(ABC) transporter
AT395_RS17615	COG0842	Transport permease protein
AT395_RS17625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AT395_RS17635	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AT395_RS17655	COG2095	MarC family integral membrane protein
AT395_RS17660	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AT395_RS17665	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AT395_RS17675	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AT395_RS17695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AT395_RS17705	COG0805	protein transport
AT395_RS17710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AT395_RS17715	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AT395_RS17725	COG0723	plastoquinol--plastocyanin reductase activity
AT395_RS17730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AT395_RS17735	COG2857	Cytochrome c1
AT395_RS17740	COG0625	glutathione transferase activity
AT395_RS17745	COG2969	positive regulation of protein catabolic process
AT395_RS17885	COG5377	YqaJ viral recombinase family
AT395_RS17985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AT395_RS18010	COG2801	Transposase and inactivated derivatives
AT395_RS18020	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS18030	COG4638	Rieske (2fe-2S)
AT395_RS18060	COG0154	amidase activity
AT395_RS18110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AT395_RS18130	COG0582	viral genome integration into host DNA
AT395_RS18135	COG0210	DNA helicase
AT395_RS18155	COG1473	amidohydrolase
AT395_RS18220	COG1454	alcohol dehydrogenase
AT395_RS18230	COG3284	Transcriptional regulator
AT395_RS18235	COG3045	CreA protein
AT395_RS18275	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AT395_RS18285	COG1215	transferase activity, transferring glycosyl groups
AT395_RS18305	COG1696	Membrane protein involved in D-alanine export
AT395_RS18310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AT395_RS18385	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AT395_RS18395	COG2271	Major facilitator Superfamily
AT395_RS18410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AT395_RS18420	COG1254	Belongs to the acylphosphatase family
AT395_RS18425	COG1408	metallophosphoesterase
AT395_RS18440	COG0488	(ABC) transporter
AT395_RS18445	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS18455	COG0835	chemotaxis
AT395_RS18460	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AT395_RS18465	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AT395_RS18490	COG0163	prenyltransferase activity
AT395_RS18495	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AT395_RS18500	COG2890	protein-(glutamine-N5) methyltransferase activity
AT395_RS18505	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AT395_RS18510	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AT395_RS18515	COG2261	transglycosylase associated protein
AT395_RS18525	COG0477	Major facilitator Superfamily
AT395_RS18540	COG0463	Glycosyl transferase, family 2
AT395_RS18565	COG0012	GTP binding
AT395_RS18570	COG2321	neutral zinc metallopeptidase
AT395_RS18575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AT395_RS18590	COG0583	DNA-binding transcription factor activity
AT395_RS18605	COG4774	siderophore transport
AT395_RS18610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AT395_RS18620	COG0134	indole-3-glycerol-phosphate synthase activity
AT395_RS18625	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AT395_RS18640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AT395_RS18645	COG4232	protein-disulfide reductase activity
AT395_RS18655	COG0642	Histidine kinase
AT395_RS18665	COG0842	Transport permease protein
AT395_RS18670	COG0842	Transport permease protein
AT395_RS18670	COG1129	ABC transporter
AT395_RS18675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AT395_RS18690	COG0546	phosphoglycolate phosphatase activity
AT395_RS18695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AT395_RS18700	COG2967	ApaG domain
AT395_RS18710	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AT395_RS18720	COG2050	protein possibly involved in aromatic compounds catabolism
AT395_RS18725	COG1024	Enoyl-CoA hydratase
AT395_RS18730	COG0183	Belongs to the thiolase family
AT395_RS18740	COG1024	Enoyl-CoA hydratase
AT395_RS18780	COG1473	amidohydrolase
AT395_RS18785	COG0243	molybdopterin cofactor binding
AT395_RS18800	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS18815	COG0275	rRNA processing
AT395_RS18820	COG3116	cell division
AT395_RS18830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AT395_RS18835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AT395_RS18845	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AT395_RS18855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AT395_RS18860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AT395_RS18865	COG1181	Belongs to the D-alanine--D-alanine ligase family
AT395_RS18870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AT395_RS18885	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AT395_RS18895	COG0653	protein targeting
AT395_RS18900	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AT395_RS18910	COG0494	nUDIX hydrolase
AT395_RS18915	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AT395_RS18940	COG4536	flavin adenine dinucleotide binding
AT395_RS18950	COG0142	geranyltranstransferase activity
AT395_RS18955	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AT395_RS18960	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AT395_RS18965	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AT395_RS18985	COG0442	prolyl-tRNA aminoacylation
AT395_RS18990	COG2095	MarC family integral membrane protein
AT395_RS18995	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AT395_RS19000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AT395_RS19005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AT395_RS19035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AT395_RS19050	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AT395_RS19050	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AT395_RS19070	COG0439	Biotin carboxylase
AT395_RS19075	COG0511	ligase activity, forming carbon-carbon bonds
AT395_RS19080	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AT395_RS19085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AT395_RS19095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AT395_RS19100	COG3150	esterase
AT395_RS19105	COG0557	exoribonuclease II activity
AT395_RS19120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AT395_RS19125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AT395_RS19130	COG0668	transmembrane transport
AT395_RS19140	COG0284	orotidine-5'-phosphate decarboxylase activity
AT395_RS19145	COG1058	Belongs to the CinA family
AT395_RS19145	COG1546	Belongs to the CinA family
AT395_RS19150	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AT395_RS19160	COG0280	phosphate acetyltransferase
AT395_RS19160	COG0281	malic enzyme
AT395_RS19165	COG4290	ribonuclease
AT395_RS19180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AT395_RS19190	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AT395_RS19195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AT395_RS19200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AT395_RS19210	COG0735	belongs to the Fur family
AT395_RS19215	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AT395_RS19225	COG0495	leucyl-tRNA aminoacylation
AT395_RS19240	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AT395_RS19250	COG2207	Transcriptional regulator
AT395_RS19265	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AT395_RS19265	COG3608	succinylglutamate desuccinylase aspartoacylase
AT395_RS19270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS19275	COG0138	bifunctional purine biosynthesis protein purh
AT395_RS19280	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AT395_RS19290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AT395_RS19295	COG0006	proline dipeptidase activity
AT395_RS19315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AT395_RS19320	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AT395_RS19335	COG1773	rubredoxin
AT395_RS19340	COG0346	lactoylglutathione lyase activity
AT395_RS19350	COG0204	Acyl-transferase
AT395_RS19355	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AT395_RS19360	COG0751	glycine-tRNA ligase activity
AT395_RS19365	COG0752	glycyl-tRNA synthetase alpha subunit
AT395_RS19370	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AT395_RS19380	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AT395_RS19385	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AT395_RS19390	COG1702	phosphate starvation-inducible protein PhoH
AT395_RS19395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AT395_RS19400	COG0803	Belongs to the bacterial solute-binding protein 9 family
AT395_RS19410	COG1121	(ABC) transporter
AT395_RS19415	COG2766	serine protein kinase
AT395_RS19420	COG2718	Belongs to the UPF0229 family
AT395_RS19425	COG2719	SpoVR family
AT395_RS19435	COG3706	GGDEF domain
AT395_RS19460	COG0668	transmembrane transport
AT395_RS19465	COG1902	pentaerythritol trinitrate reductase activity
AT395_RS19480	COG0840	transmembrane signaling receptor activity
AT395_RS19485	COG1396	sequence-specific DNA binding
AT395_RS19490	COG0156	8-amino-7-oxononanoate synthase activity
AT395_RS19495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AT395_RS19505	COG1116	anion transmembrane transporter activity
AT395_RS19520	COG0628	permease
AT395_RS19525	COG0583	DNA-binding transcription factor activity
AT395_RS19530	COG0861	Integral membrane protein TerC family
AT395_RS19560	COG0477	Major facilitator Superfamily
AT395_RS19565	COG0642	Histidine kinase
AT395_RS19575	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AT395_RS19580	COG2137	regulation of response to DNA damage stimulus
AT395_RS19590	COG0045	succinate-CoA ligase (ADP-forming) activity
AT395_RS19595	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AT395_RS19600	COG0861	Integral membrane protein TerC family
AT395_RS19605	COG4969	Belongs to the N-Me-Phe pilin family
AT395_RS19620	COG1773	rubredoxin
AT395_RS19630	COG1678	Uncharacterized ACR, COG1678
AT395_RS19635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AT395_RS19640	COG0540	Belongs to the ATCase OTCase family
AT395_RS19655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AT395_RS19660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AT395_RS19665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AT395_RS19670	COG0438	transferase activity, transferring glycosyl groups
AT395_RS19675	COG0438	transferase activity, transferring glycosyl groups
AT395_RS19680	COG0438	transferase activity, transferring glycosyl groups
AT395_RS19720	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AT395_RS19745	COG1968	undecaprenyl-diphosphatase activity
AT395_RS19760	COG2814	Major facilitator Superfamily
AT395_RS19785	COG2814	Major facilitator Superfamily
AT395_RS19795	COG0583	DNA-binding transcription factor activity
AT395_RS19805	COG0789	Transcriptional regulator
AT395_RS19810	COG4372	Transposase
AT395_RS19825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AT395_RS19830	COG0501	Belongs to the peptidase M48B family
AT395_RS19875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AT395_RS19885	COG0542	response to heat
AT395_RS19890	COG0071	Belongs to the small heat shock protein (HSP20) family
AT395_RS19905	COG0583	DNA-binding transcription factor activity
AT395_RS19920	COG1192	Involved in chromosome partitioning
AT395_RS20095	COG3621	Patatin-like phospholipase
AT395_RS20170	COG2003	Belongs to the UPF0758 family
AT395_RS20230	COG0582	viral genome integration into host DNA
AT395_RS20245	COG1278	Cold shock
AT395_RS20255	COG0405	Gamma-glutamyltransferase
AT395_RS20265	COG1846	Transcriptional regulator
AT395_RS20270	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AT395_RS20305	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AT395_RS20310	COG2814	Major facilitator Superfamily
AT395_RS20345	COG3781	membrane
AT395_RS20370	COG2031	fatty acid transporter
AT395_RS20400	COG0531	amino acid
AT395_RS20435	COG2885	chlorophyll binding
AT395_RS20450	COG2855	membrane
AT395_RS20480	COG2198	Histidine kinase
AT395_RS20480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT395_RS20480	COG0784	Response regulator, receiver
AT395_RS20480	COG2205	protein histidine kinase activity
AT395_RS20490	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AT395_RS20505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AT395_RS20515	COG2807	transmembrane transport
AT395_RS20525	COG0534	Mate efflux family protein
AT395_RS20535	COG1280	lysine exporter protein (LysE YggA)
AT395_RS20540	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AT395_RS20545	COG3416	Protein conserved in bacteria
AT395_RS20545	COG2943	transferase activity, transferring hexosyl groups
AT395_RS20550	COG4942	peptidase
AT395_RS20555	COG1278	Cold shock
AT395_RS20560	COG1280	lysine exporter protein (LysE YggA)
AT395_RS20565	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AT395_RS20575	COG1253	flavin adenine dinucleotide binding
AT395_RS20580	COG0583	DNA-binding transcription factor activity
AT395_RS20585	COG3384	dioxygenase
AT395_RS20595	COG0247	lactate metabolic process
AT395_RS20600	COG0277	FAD linked oxidase domain protein
AT395_RS20605	COG0277	FAD linked oxidase domain protein
AT395_RS20630	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AT395_RS20635	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AT395_RS20640	COG1556	Lactate utilization protein
AT395_RS20670	COG0303	'Molybdopterin
AT395_RS20675	COG0746	molybdenum cofactor guanylyltransferase activity
AT395_RS20685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AT395_RS20690	COG1530	ribonuclease E activity
AT395_RS20695	COG0564	pseudouridine synthase activity
AT395_RS20700	COG0546	phosphoglycolate phosphatase activity
AT395_RS20710	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AT395_RS20710	COG0616	signal peptide processing
AT395_RS20715	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AT395_RS20725	COG1399	metal-binding, possibly nucleic acid-binding protein
AT395_RS20730	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AT395_RS20735	COG0416	fatty acid biosynthetic process
AT395_RS20740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AT395_RS20750	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS20755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AT395_RS20760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AT395_RS20780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AT395_RS20800	COG0681	Belongs to the peptidase S26 family
AT395_RS20805	COG0571	ribonuclease III activity
AT395_RS20810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AT395_RS20815	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AT395_RS20820	COG0736	holo-[acyl-carrier-protein] synthase activity
AT395_RS20840	COG0322	excinuclease ABC activity
AT395_RS20845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AT395_RS20895	COG2188	Transcriptional regulator
AT395_RS20900	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS20905	COG4948	Mandelate Racemase Muconate Lactonizing
AT395_RS20915	COG3842	ATPase activity
AT395_RS20945	COG0583	DNA-binding transcription factor activity
AT395_RS20950	COG1335	isochorismatase
AT395_RS20985	COG2721	sulfolactate sulfo-lyase activity
AT395_RS20995	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AT395_RS21025	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AT395_RS21055	COG3038	cytochrome b561
AT395_RS21080	COG1126	abc transporter atp-binding protein
AT395_RS21085	COG0765	amino acid transport
AT395_RS21090	COG0765	amino acid transport
AT395_RS21105	COG4633	Protein conserved in bacteria
AT395_RS21110	COG0672	)-iron permease
AT395_RS21120	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AT395_RS21135	COG0386	Belongs to the glutathione peroxidase family
AT395_RS21145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT395_RS21150	COG0277	FAD linked oxidase domain protein
AT395_RS21155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AT395_RS21160	COG0277	FAD linked oxidase domain protein
AT395_RS21165	COG0277	FAD linked oxidase domain protein
AT395_RS21170	COG2096	Adenosyltransferase
AT395_RS21175	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AT395_RS21180	COG0312	modulator of DNA gyrase
AT395_RS21185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AT395_RS21195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AT395_RS21200	COG0497	DNA recombination
AT395_RS21220	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AT395_RS21235	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AT395_RS21245	COG0443	Heat shock 70 kDa protein
AT395_RS21255	COG0512	Glutamine amidotransferase of anthranilate synthase
AT395_RS21255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AT395_RS21280	COG0641	radical SAM
AT395_RS21290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS21305	COG0642	Histidine kinase
AT395_RS21315	COG1428	Deoxynucleoside kinase
AT395_RS21320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AT395_RS21325	COG0617	tRNA 3'-terminal CCA addition
AT395_RS21335	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AT395_RS21340	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AT395_RS21350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AT395_RS21355	COG0006	proline dipeptidase activity
AT395_RS21360	COG1176	ABC-type spermidine putrescine transport system, permease component I
AT395_RS21380	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AT395_RS21385	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AT395_RS21390	COG0586	Pfam SNARE associated Golgi protein
AT395_RS21395	COG0860	N-Acetylmuramoyl-L-alanine amidase
AT395_RS21400	COG0802	atpase or kinase
AT395_RS21405	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AT395_RS21410	COG4974	Belongs to the 'phage' integrase family
AT395_RS21415	COG0318	PFAM AMP-dependent synthetase and ligase
AT395_RS21420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AT395_RS21425	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AT395_RS21430	COG1666	GTP binding
AT395_RS21445	COG3123	guanosine phosphorylase activity
AT395_RS21450	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AT395_RS21465	COG0268	Binds directly to 16S ribosomal RNA
AT395_RS21470	COG0728	peptidoglycan biosynthetic process
AT395_RS21475	COG2912	Transglutaminase-like superfamily
AT395_RS21490	COG0563	adenylate kinase activity
AT395_RS21495	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AT395_RS21500	COG2835	tetraacyldisaccharide 4'-kinase activity
AT395_RS21515	COG0811	peptide transport
AT395_RS21520	COG1570	exodeoxyribonuclease VII activity
AT395_RS21525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AT395_RS21570	COG0583	DNA-binding transcription factor activity
AT395_RS21575	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS21610	COG1278	Cold shock
AT395_RS21615	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AT395_RS21620	COG0542	response to heat
AT395_RS21630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AT395_RS21635	COG2814	Major facilitator Superfamily
AT395_RS21640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AT395_RS21645	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AT395_RS21650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AT395_RS21655	COG0196	riboflavin kinase activity
AT395_RS21660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AT395_RS21665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AT395_RS21665	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AT395_RS21670	COG3264	Mechanosensitive ion channel
AT395_RS21670	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AT395_RS21680	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AT395_RS21690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AT395_RS21695	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AT395_RS21705	COG2003	Belongs to the UPF0758 family
AT395_RS21710	COG1047	Peptidyl-prolyl cis-trans
AT395_RS21715	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AT395_RS21735	COG0411	ABC transporter
AT395_RS21755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AT395_RS21760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AT395_RS21760	COG0543	2 iron, 2 sulfur cluster binding
AT395_RS21780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AT395_RS21825	COG0280	phosphate acetyltransferase
AT395_RS21825	COG0281	malic enzyme
AT395_RS21830	COG0765	amino acid transport
AT395_RS21835	COG0765	amino acid transport
AT395_RS21840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT395_RS21855	COG0583	DNA-binding transcription factor activity
AT395_RS21880	COG0477	Major facilitator Superfamily
AT395_RS21890	COG2916	Histone family protein nucleoid-structuring protein H-NS
AT395_RS21910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AT395_RS21915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AT395_RS21920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AT395_RS21930	COG2197	response regulator
AT395_RS21935	COG1289	transmembrane transporter activity
AT395_RS21940	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AT395_RS21945	COG1074	ATP-dependent DNA helicase activity
AT395_RS21950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AT395_RS21955	COG1253	flavin adenine dinucleotide binding
AT395_RS21965	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AT395_RS21975	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AT395_RS21990	COG0655	NAD(P)H dehydrogenase (quinone) activity
AT395_RS22000	COG0583	DNA-binding transcription factor activity
AT395_RS22010	COG0513	Belongs to the DEAD box helicase family
AT395_RS22015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AT395_RS22020	COG1054	Belongs to the UPF0176 family
AT395_RS22070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AT395_RS22075	COG1530	ribonuclease E activity
AT395_RS22080	COG0424	maF-like protein
AT395_RS22085	COG0584	glycerophosphoryl diester phosphodiesterase
AT395_RS22095	COG0395	ABC-type sugar transport system, permease component
AT395_RS22100	COG1175	transmembrane transport
AT395_RS22105	COG1653	transport
AT395_RS22110	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AT395_RS22115	COG0799	negative regulation of ribosome biogenesis
AT395_RS22130	COG0668	transmembrane transport
AT395_RS22135	COG0151	Belongs to the GarS family
AT395_RS22140	COG0217	transcriptional regulatory protein
AT395_RS22145	COG0433	COG0433 Predicted ATPase
AT395_RS22155	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AT395_RS22160	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS22165	COG1803	Methylglyoxal synthase
AT395_RS22180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AT395_RS22185	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS22190	COG3284	Transcriptional regulator
AT395_RS22195	COG0583	DNA-binding transcription factor activity
AT395_RS22200	COG1802	Transcriptional regulator
AT395_RS22205	COG1454	alcohol dehydrogenase
AT395_RS22210	COG0477	Major facilitator Superfamily
AT395_RS22220	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS22230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AT395_RS22235	COG0183	Belongs to the thiolase family
AT395_RS22265	COG0436	Aminotransferase
AT395_RS22275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AT395_RS22315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AT395_RS22340	COG0583	DNA-binding transcription factor activity
AT395_RS22345	COG2197	response regulator
AT395_RS22380	COG1846	Transcriptional regulator
AT395_RS22385	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS22390	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AT395_RS22400	COG0318	PFAM AMP-dependent synthetase and ligase
AT395_RS22405	COG1960	acyl-CoA dehydrogenase activity
AT395_RS22410	COG0477	Major facilitator Superfamily
AT395_RS22415	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AT395_RS22425	COG0243	molybdopterin cofactor binding
AT395_RS22435	COG3707	response regulator
AT395_RS22440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AT395_RS22450	COG2824	Alkylphosphonate utilization operon protein PhnA
AT395_RS22475	COG1309	transcriptional regulator
AT395_RS22480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AT395_RS22485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AT395_RS22500	COG0673	inositol 2-dehydrogenase activity
AT395_RS22520	COG1988	membrane-bound metal-dependent
AT395_RS22525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AT395_RS22575	COG0747	negative chemotaxis
AT395_RS22580	COG4608	Belongs to the ABC transporter superfamily
AT395_RS22585	COG0444	Belongs to the ABC transporter superfamily
AT395_RS22590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AT395_RS22595	COG0601	transmembrane transport
AT395_RS22600	COG2072	flavoprotein involved in K transport
AT395_RS22610	COG1199	ATP-dependent helicase activity
AT395_RS22610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AT395_RS22625	COG3706	GGDEF domain
AT395_RS22635	COG1802	Transcriptional regulator
AT395_RS22650	COG0596	Alpha beta hydrolase
AT395_RS22680	COG2010	Cytochrome c
AT395_RS22695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AT395_RS22700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AT395_RS22700	COG0785	Cytochrome C biogenesis protein
AT395_RS22705	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AT395_RS22710	COG0745	RESPONSE REGULATOR receiver
AT395_RS22715	COG2205	protein histidine kinase activity
AT395_RS22730	COG0071	Belongs to the small heat shock protein (HSP20) family
AT395_RS22750	COG0459	protein refolding
AT395_RS22765	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AT395_RS22775	COG3040	lipid binding
AT395_RS22800	COG0459	protein refolding
AT395_RS22805	COG0583	DNA-binding transcription factor activity
AT395_RS22815	COG1846	Transcriptional regulator
AT395_RS22820	COG0697	spore germination
AT395_RS22825	COG0315	cyclic pyranopterin monophosphate synthase activity
AT395_RS22845	COG0429	hydrolase of the alpha beta-hydrolase fold
AT395_RS22875	COG0126	phosphoglycerate kinase activity
AT395_RS22880	COG0469	pyruvate kinase activity
AT395_RS22900	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AT395_RS22905	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AT395_RS22910	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AT395_RS22915	COG0009	L-threonylcarbamoyladenylate synthase
AT395_RS22925	COG2027	D-alanyl-D-alanine carboxypeptidase
AT395_RS22945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AT395_RS22955	COG3608	succinylglutamate desuccinylase aspartoacylase
AT395_RS22955	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AT395_RS22970	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AT395_RS22975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AT395_RS22985	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AT395_RS22990	COG4149	molybdate abc transporter
AT395_RS22995	COG0725	ABC transporter, periplasmic molybdate-binding protein
AT395_RS23000	COG1309	transcriptional regulator
AT395_RS23010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AT395_RS23050	COG4575	ribosome binding
AT395_RS23055	COG0450	alkyl hydroperoxide reductase
AT395_RS23060	COG1960	acyl-CoA dehydrogenase activity
AT395_RS23070	COG3483	tryptophan 2,3-dioxygenase activity
AT395_RS23080	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AT395_RS23095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AT395_RS23100	COG2309	aminopeptidase activity
AT395_RS23125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT395_RS23130	COG0765	amino acid transport
AT395_RS23135	COG1126	abc transporter atp-binding protein
AT395_RS23140	COG0010	Belongs to the arginase family
AT395_RS23145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AT395_RS23160	COG0477	Major facilitator Superfamily
AT395_RS23165	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AT395_RS23175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AT395_RS23180	COG0259	pyridoxamine-phosphate oxidase activity
AT395_RS23185	COG2982	Protein involved in outer membrane biogenesis
AT395_RS23190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AT395_RS23195	COG0318	PFAM AMP-dependent synthetase and ligase
AT395_RS23225	COG1309	transcriptional regulator
AT395_RS23230	COG1113	amino acid transport
AT395_RS23235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS23240	COG1522	sequence-specific DNA binding
AT395_RS23245	COG1304	FMN binding
AT395_RS23255	COG0583	DNA-binding transcription factor activity
AT395_RS23270	COG0154	amidase activity
AT395_RS23300	COG1116	anion transmembrane transporter activity
AT395_RS23310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AT395_RS23320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AT395_RS23325	COG1960	acyl-CoA dehydrogenase activity
AT395_RS23335	COG2897	thiosulfate sulfurtransferase activity
AT395_RS23350	COG1454	alcohol dehydrogenase
AT395_RS23380	COG1012	belongs to the aldehyde dehydrogenase family
AT395_RS23385	COG1414	Transcriptional regulator
AT395_RS23395	COG1802	Transcriptional regulator
AT395_RS23400	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AT395_RS23405	COG2271	Major facilitator Superfamily
AT395_RS23410	COG0277	FAD linked oxidase domain protein
AT395_RS23410	COG0247	lactate metabolic process
AT395_RS23455	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS23495	COG0842	Transport permease protein
AT395_RS23500	COG1131	(ABC) transporter
AT395_RS23520	COG0583	DNA-binding transcription factor activity
AT395_RS23525	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS23535	COG1522	sequence-specific DNA binding
AT395_RS23540	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS23545	COG2271	Major facilitator Superfamily
AT395_RS23550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AT395_RS23575	COG0129	dihydroxy-acid dehydratase activity
AT395_RS23595	COG1764	response to oxidative stress
AT395_RS23605	COG2900	Belongs to the SlyX family
AT395_RS23610	COG1742	UPF0060 membrane protein
AT395_RS23625	COG0583	DNA-binding transcription factor activity
AT395_RS23635	COG1522	sequence-specific DNA binding
AT395_RS23640	COG1280	lysine exporter protein (LysE YggA)
AT395_RS23645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AT395_RS23655	COG1845	cytochrome c oxidase, subunit III
AT395_RS23660	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AT395_RS23695	COG0583	DNA-binding transcription factor activity
AT395_RS23700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AT395_RS23705	COG1305	Transglutaminase-like
AT395_RS23735	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AT395_RS23755	COG0693	protein deglycase activity
AT395_RS23770	COG0583	DNA-binding transcription factor activity
AT395_RS23775	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS23775	COG0604	alcohol dehydrogenase
AT395_RS23775	COG3321	synthase
AT395_RS23785	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AT395_RS23800	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS23805	COG0583	DNA-binding transcription factor activity
AT395_RS23820	COG1012	belongs to the aldehyde dehydrogenase family
AT395_RS23850	COG0583	DNA-binding transcription factor activity
AT395_RS23895	COG1917	Cupin 2, conserved barrel domain protein
AT395_RS23925	COG4208	sulfate ABC transporter
AT395_RS23935	COG3842	ATPase activity
AT395_RS23940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AT395_RS23945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AT395_RS23945	COG1017	nitric oxide dioxygenase activity
AT395_RS23970	COG0540	Belongs to the ATCase OTCase family
AT395_RS23990	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AT395_RS23995	COG2271	Major facilitator Superfamily
AT395_RS24000	COG4106	trans-aconitate 2-methyltransferase activity
AT395_RS24005	COG0583	DNA-binding transcription factor activity
AT395_RS24020	COG0308	aminopeptidase N
AT395_RS24030	COG2119	membrane
AT395_RS24035	COG0402	S-adenosylhomocysteine deaminase activity
AT395_RS24040	COG2252	PERMEase
AT395_RS24045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AT395_RS24055	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AT395_RS24070	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AT395_RS24085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AT395_RS24085	COG4651	solute:proton antiporter activity
AT395_RS24095	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AT395_RS24100	COG2608	mercury ion transmembrane transporter activity
AT395_RS24105	COG2217	Heavy metal translocating P-type atpase
AT395_RS24110	COG3568	Endonuclease Exonuclease Phosphatase
AT395_RS24115	COG0789	Transcriptional regulator
AT395_RS24145	COG1914	H( )-stimulated, divalent metal cation uptake system
AT395_RS24160	COG0587	DNA-directed DNA polymerase activity
AT395_RS24165	COG2233	PERMEase
AT395_RS24190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AT395_RS24205	COG0513	Belongs to the DEAD box helicase family
AT395_RS24230	COG2252	PERMEase
AT395_RS24250	COG1283	sodium-dependent phosphate transmembrane transporter activity
AT395_RS24255	COG2814	Major facilitator Superfamily
AT395_RS24265	COG2271	Major facilitator Superfamily
AT395_RS24290	COG0328	RNA-DNA hybrid ribonuclease activity
AT395_RS24300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AT395_RS24305	COG0741	lytic transglycosylase activity
AT395_RS24305	COG1388	LysM domain
AT395_RS24320	COG0583	DNA-binding transcription factor activity
AT395_RS24340	COG1028	Short-chain dehydrogenase reductase Sdr
AT395_RS24345	COG1024	Enoyl-CoA hydratase
AT395_RS24350	COG1960	acyl-CoA dehydrogenase activity
AT395_RS24375	COG4266	Belongs to the allantoicase family
AT395_RS24380	COG1301	dicarboxylic acid transport
AT395_RS24400	COG0505	Belongs to the CarA family
AT395_RS24410	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AT395_RS24415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AT395_RS24425	COG1534	Rna-binding protein
AT395_RS24435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AT395_RS24450	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AT395_RS24455	COG0573	inorganic phosphate transmembrane transporter activity
AT395_RS24460	COG0581	inorganic phosphate transmembrane transporter activity
AT395_RS24465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AT395_RS24475	COG0745	RESPONSE REGULATOR receiver
AT395_RS24485	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AT395_RS24500	COG2062	phosphohistidine phosphatase, SixA
AT395_RS24535	COG1595	DNA-templated transcription, initiation
AT395_RS24555	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT395_RS24560	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AT395_RS24580	COG0582	viral genome integration into host DNA
AT395_RS24630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease