locus-tag	class	description
AB870_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AB870_RS00010	COG0592	DNA-directed DNA polymerase activity
AB870_RS00025	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AB870_RS00040	COG0477	Major facilitator Superfamily
AB870_RS00055	COG0840	transmembrane signaling receptor activity
AB870_RS00090	COG3842	ATPase activity
AB870_RS00105	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AB870_RS00115	COG0583	DNA-binding transcription factor activity
AB870_RS00120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB870_RS00125	COG0765	amino acid transport
AB870_RS00130	COG0765	amino acid transport
AB870_RS00165	COG1252	NADH dehydrogenase
AB870_RS00170	COG1309	transcriptional regulator
AB870_RS00190	COG4774	siderophore transport
AB870_RS00195	COG3712	iron ion homeostasis
AB870_RS00205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AB870_RS00220	COG1968	undecaprenyl-diphosphatase activity
AB870_RS00225	COG0583	DNA-binding transcription factor activity
AB870_RS00270	COG2252	PERMEase
AB870_RS00275	COG0583	DNA-binding transcription factor activity
AB870_RS00300	COG2733	membrane
AB870_RS00305	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AB870_RS00310	COG3340	Belongs to the peptidase S51 family
AB870_RS00335	COG0583	DNA-binding transcription factor activity
AB870_RS00345	COG0583	DNA-binding transcription factor activity
AB870_RS00350	COG2814	Major facilitator Superfamily
AB870_RS00365	COG2771	luxR family
AB870_RS00365	COG2200	EAL domain
AB870_RS00370	COG2223	nitrite transmembrane transporter activity
AB870_RS00395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AB870_RS00405	COG0840	transmembrane signaling receptor activity
AB870_RS00420	COG0835	chemotaxis
AB870_RS00430	COG2201	protein-glutamate methylesterase activity
AB870_RS00435	COG3706	GGDEF domain
AB870_RS00435	COG5001	Diguanylate cyclase
AB870_RS00435	COG2203	Gaf domain
AB870_RS00435	COG4251	negative regulation of phosphorylation
AB870_RS00455	COG2801	Transposase and inactivated derivatives
AB870_RS00465	COG1473	amidohydrolase
AB870_RS00475	COG0183	Belongs to the thiolase family
AB870_RS00515	COG1802	Transcriptional regulator
AB870_RS00520	COG2957	Belongs to the agmatine deiminase family
AB870_RS00530	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AB870_RS00530	COG1672	PFAM Archaeal ATPase
AB870_RS00535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB870_RS00540	COG4774	siderophore transport
AB870_RS00545	COG3128	pkhd-type hydroxylase
AB870_RS00570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AB870_RS00575	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AB870_RS00600	COG1966	Carbon starvation protein
AB870_RS00605	COG2879	small protein
AB870_RS00615	COG0583	DNA-binding transcription factor activity
AB870_RS00630	COG0758	DNA mediated transformation
AB870_RS00635	COG0242	peptide deformylase activity
AB870_RS00645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AB870_RS00650	COG0501	Belongs to the peptidase M48B family
AB870_RS00655	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AB870_RS00655	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AB870_RS00665	COG5000	phosphorelay sensor kinase activity
AB870_RS00670	COG2204	response regulator
AB870_RS00670	COG2204	response regulator
AB870_RS00680	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AB870_RS00685	COG0602	queuosine metabolic process
AB870_RS00690	COG0720	synthase
AB870_RS00745	COG2207	Transcriptional regulator
AB870_RS00875	COG0772	Belongs to the SEDS family
AB870_RS00880	COG0768	penicillin binding
AB870_RS00890	COG1792	Involved in formation and maintenance of cell shape
AB870_RS00895	COG1077	Cell shape determining protein MreB Mrl
AB870_RS00900	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AB870_RS00915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AB870_RS00920	COG2326	polyphosphate kinase activity
AB870_RS00925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB870_RS00970	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AB870_RS00980	COG1960	acyl-CoA dehydrogenase activity
AB870_RS00990	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AB870_RS00995	COG1560	Kdo2-lipid A biosynthetic process
AB870_RS01000	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AB870_RS01010	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AB870_RS01015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AB870_RS01030	COG0523	cobalamin synthesis protein
AB870_RS01050	COG4206	TonB-dependent receptor
AB870_RS01055	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AB870_RS01060	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AB870_RS01065	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AB870_RS01085	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AB870_RS01105	COG0477	Major facilitator Superfamily
AB870_RS01120	COG2188	Transcriptional regulator
AB870_RS01130	COG3384	dioxygenase
AB870_RS01140	COG0683	leucine binding
AB870_RS01165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AB870_RS01170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AB870_RS01175	COG2828	Protein conserved in bacteria
AB870_RS01190	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS01195	COG2814	Major facilitator Superfamily
AB870_RS01205	COG1309	transcriptional regulator
AB870_RS01210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB870_RS01215	COG2813	Specifically methylates the guanine in position
AB870_RS01215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB870_RS01220	COG2814	Major facilitator Superfamily
AB870_RS01225	COG0708	Exodeoxyribonuclease III
AB870_RS01230	COG0583	DNA-binding transcription factor activity
AB870_RS01235	COG1380	Effector of murein hydrolase LrgA
AB870_RS01240	COG1346	cytolysis
AB870_RS01245	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AB870_RS01250	COG1950	PFAM Membrane protein of
AB870_RS01260	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AB870_RS01265	COG0747	negative chemotaxis
AB870_RS01270	COG0601	transmembrane transport
AB870_RS01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB870_RS01280	COG0444	Belongs to the ABC transporter superfamily
AB870_RS01285	COG4608	Belongs to the ABC transporter superfamily
AB870_RS01295	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AB870_RS01300	COG0830	nickel cation binding
AB870_RS01305	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AB870_RS01310	COG0804	urea catabolic process
AB870_RS01315	COG0832	Belongs to the urease beta subunit family
AB870_RS01325	COG0831	urea catabolic process
AB870_RS01330	COG1126	abc transporter atp-binding protein
AB870_RS01335	COG0765	amino acid transport
AB870_RS01340	COG0765	amino acid transport
AB870_RS01385	COG2814	Major facilitator Superfamily
AB870_RS01400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB870_RS01405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AB870_RS01410	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AB870_RS01415	COG1984	allophanate hydrolase subunit 2
AB870_RS01420	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AB870_RS01480	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AB870_RS01500	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS01570	COG0137	argininosuccinate synthase activity
AB870_RS01575	COG0583	DNA-binding transcription factor activity
AB870_RS01595	COG0625	glutathione transferase activity
AB870_RS01600	COG0583	DNA-binding transcription factor activity
AB870_RS01640	COG0583	DNA-binding transcription factor activity
AB870_RS01650	COG1090	epimerase
AB870_RS01665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AB870_RS01665	COG2169	Transcriptional regulator
AB870_RS01685	COG1741	Belongs to the pirin family
AB870_RS01695	COG1739	Uncharacterized protein family UPF0029
AB870_RS01705	COG2132	Multicopper oxidase
AB870_RS01745	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB870_RS01795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AB870_RS01800	COG4681	YaeQ
AB870_RS01805	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AB870_RS01820	COG0697	spore germination
AB870_RS01835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS01840	COG4770	biotin carboxylase activity
AB870_RS01845	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AB870_RS01850	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AB870_RS01855	COG0156	8-amino-7-oxononanoate synthase activity
AB870_RS01865	COG1024	Enoyl-CoA hydratase
AB870_RS01870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AB870_RS01875	COG3012	SEC-C Motif Domain Protein
AB870_RS01885	COG0300	oxidoreductase activity
AB870_RS01890	COG0183	Belongs to the thiolase family
AB870_RS01895	COG0288	reversible hydration of carbon dioxide
AB870_RS01900	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AB870_RS01905	COG1960	acyl-CoA dehydrogenase activity
AB870_RS01915	COG0789	Transcriptional regulator
AB870_RS01920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB870_RS01935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB870_RS01940	COG2814	Major facilitator Superfamily
AB870_RS01975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AB870_RS01985	COG0018	arginyl-trna synthetase
AB870_RS02000	COG1285	pathogenesis
AB870_RS02005	COG0646	methionine synthase
AB870_RS02005	COG1410	methionine synthase
AB870_RS02025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB870_RS02075	COG1279	arginine transmembrane transporter activity
AB870_RS02095	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AB870_RS02120	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB870_RS02125	COG1127	ABC transporter
AB870_RS02145	COG2814	Major facilitator Superfamily
AB870_RS02160	COG1686	Belongs to the peptidase S11 family
AB870_RS02165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AB870_RS02170	COG2921	Belongs to the UPF0250 family
AB870_RS02175	COG0583	DNA-binding transcription factor activity
AB870_RS02190	COG0321	lipoyl(octanoyl) transferase activity
AB870_RS02225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB870_RS02230	COG1116	anion transmembrane transporter activity
AB870_RS02235	COG1301	dicarboxylic acid transport
AB870_RS02240	COG4191	Histidine kinase
AB870_RS02245	COG2204	response regulator
AB870_RS02250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB870_RS02265	COG0606	chelatase, subunit chli
AB870_RS02270	COG2960	long-chain fatty acid transporting porin activity
AB870_RS02280	COG0347	Belongs to the P(II) protein family
AB870_RS02285	COG0004	ammonium transporteR
AB870_RS02300	COG0189	ligase activity
AB870_RS02310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB870_RS02315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AB870_RS02320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AB870_RS02325	COG0793	Belongs to the peptidase S41A family
AB870_RS02335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AB870_RS02340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AB870_RS02345	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AB870_RS02355	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AB870_RS02365	COG1040	competence protein
AB870_RS02370	COG2226	methyltransferase
AB870_RS02375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AB870_RS02380	COG2423	ornithine cyclodeaminase activity
AB870_RS02385	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AB870_RS02395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AB870_RS02400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AB870_RS02410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB870_RS02415	COG2771	luxR family
AB870_RS02435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AB870_RS02440	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AB870_RS02470	COG1612	heme a metabolic process
AB870_RS02480	COG1999	signal sequence binding
AB870_RS02490	COG1294	oxidase, subunit
AB870_RS02505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AB870_RS02515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AB870_RS02520	COG0625	glutathione transferase activity
AB870_RS02535	COG0612	Peptidase, M16
AB870_RS02540	COG0612	Peptidase, M16
AB870_RS02550	COG1131	(ABC) transporter
AB870_RS02555	COG0742	ribosomal rna small subunit methyltransferase
AB870_RS02560	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AB870_RS02570	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AB870_RS02575	COG0193	aminoacyl-tRNA hydrolase activity
AB870_RS02585	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AB870_RS02600	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AB870_RS02615	COG1194	a g-specific adenine glycosylase
AB870_RS02620	COG1660	Displays ATPase and GTPase activities
AB870_RS02630	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AB870_RS02640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AB870_RS02645	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AB870_RS02650	COG1137	ATPase activity
AB870_RS02665	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AB870_RS02680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AB870_RS02695	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AB870_RS02700	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AB870_RS02705	COG3639	organic phosphonate transmembrane transporter activity
AB870_RS02710	COG3454	Phosphonate metabolism
AB870_RS02715	COG4778	phosphonate C-P lyase system protein PhnL
AB870_RS02720	COG4107	phosphonate C-P lyase system protein PhnK
AB870_RS02725	COG3627	carbon phosphorus lyase activity
AB870_RS02730	COG3626	phosphonate metabolism
AB870_RS02735	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AB870_RS02740	COG3624	Phosphonate C-P lyase system protein PhnG
AB870_RS02745	COG2188	Transcriptional regulator
AB870_RS02750	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AB870_RS02765	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AB870_RS02785	COG0477	Major facilitator Superfamily
AB870_RS02795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AB870_RS02805	COG3842	ATPase activity
AB870_RS02810	COG1840	ABC-type Fe3 transport system, periplasmic component
AB870_RS02825	COG1012	belongs to the aldehyde dehydrogenase family
AB870_RS02830	COG1283	sodium-dependent phosphate transmembrane transporter activity
AB870_RS02840	COG0251	oxidation-reduction process
AB870_RS02865	COG2814	Major facilitator Superfamily
AB870_RS02870	COG0629	single-stranded DNA binding
AB870_RS02915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB870_RS02930	COG1418	mRNA catabolic process
AB870_RS02950	COG1473	amidohydrolase
AB870_RS02965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB870_RS02970	COG1012	belongs to the aldehyde dehydrogenase family
AB870_RS03000	COG0625	glutathione transferase activity
AB870_RS03030	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS03040	COG2207	Transcriptional regulator
AB870_RS03065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AB870_RS03070	COG2271	Major facilitator Superfamily
AB870_RS03075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB870_RS03080	COG0625	glutathione transferase activity
AB870_RS03105	COG0583	DNA-binding transcription factor activity
AB870_RS03110	COG0477	Major facilitator Superfamily
AB870_RS03115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AB870_RS03135	COG0318	PFAM AMP-dependent synthetase and ligase
AB870_RS03140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB870_RS03145	COG0601	transmembrane transport
AB870_RS03160	COG0604	alcohol dehydrogenase
AB870_RS03160	COG3321	synthase
AB870_RS03160	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS03180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB870_RS03190	COG0765	amino acid transport
AB870_RS03195	COG0010	Belongs to the arginase family
AB870_RS03200	COG1126	abc transporter atp-binding protein
AB870_RS03225	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AB870_RS03270	COG4191	Histidine kinase
AB870_RS03290	COG2610	gluconate transmembrane transporter activity
AB870_RS03300	COG1733	regulation of RNA biosynthetic process
AB870_RS03305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB870_RS03310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB870_RS03315	COG0656	L-ascorbic acid biosynthetic process
AB870_RS03320	COG3038	cytochrome b561
AB870_RS03325	COG4771	TonB-dependent receptor
AB870_RS03335	COG3047	cAMP biosynthetic process
AB870_RS03340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB870_RS03345	COG0583	DNA-binding transcription factor activity
AB870_RS03350	COG2226	methyltransferase
AB870_RS03360	COG0625	glutathione transferase activity
AB870_RS03370	COG1448	Aminotransferase
AB870_RS03390	COG2814	Major facilitator Superfamily
AB870_RS03395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AB870_RS03400	COG0183	Belongs to the thiolase family
AB870_RS03405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AB870_RS03415	COG1414	Transcriptional regulator
AB870_RS03450	COG1942	4-Oxalocrotonate Tautomerase
AB870_RS03480	COG2814	Major facilitator Superfamily
AB870_RS03495	COG0583	DNA-binding transcription factor activity
AB870_RS03505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB870_RS03525	COG0583	DNA-binding transcription factor activity
AB870_RS03530	COG1902	pentaerythritol trinitrate reductase activity
AB870_RS03535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AB870_RS03570	COG1414	Transcriptional regulator
AB870_RS03575	COG1414	Transcriptional regulator
AB870_RS03590	COG0730	response to heat
AB870_RS03595	COG0280	phosphate acetyltransferase
AB870_RS03620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AB870_RS03625	COG1228	amidohydrolase
AB870_RS03640	COG1113	amino acid transport
AB870_RS03645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB870_RS03650	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AB870_RS03655	COG4521	taurine ABC transporter
AB870_RS03660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB870_RS03670	COG0697	spore germination
AB870_RS03680	COG4566	intracellular signal transduction
AB870_RS03685	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AB870_RS03690	COG0656	L-ascorbic acid biosynthetic process
AB870_RS03695	COG0583	DNA-binding transcription factor activity
AB870_RS03705	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AB870_RS03715	COG0833	amino acid
AB870_RS03725	COG1120	ATPase activity
AB870_RS03735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB870_RS03740	COG0477	Major facilitator Superfamily
AB870_RS03760	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AB870_RS03780	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AB870_RS03780	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AB870_RS03790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AB870_RS03800	COG1238	metal cluster binding
AB870_RS03820	COG0025	NhaP-type Na H and K H
AB870_RS03835	COG2226	methyltransferase
AB870_RS03850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AB870_RS03870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AB870_RS03875	COG0494	nUDIX hydrolase
AB870_RS03880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB870_RS03890	COG1960	acyl-CoA dehydrogenase activity
AB870_RS03895	COG1024	Enoyl-CoA hydratase
AB870_RS03895	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB870_RS03900	COG0183	Belongs to the thiolase family
AB870_RS03915	COG5265	(ABC) transporter
AB870_RS03925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AB870_RS03935	COG0765	amino acid transport
AB870_RS03940	COG0765	amino acid transport
AB870_RS03945	COG1126	abc transporter atp-binding protein
AB870_RS03950	COG0121	glutamine amidotransferase
AB870_RS03955	COG0418	dihydroorotase activity
AB870_RS03970	COG1765	OsmC-like protein
AB870_RS03975	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AB870_RS03980	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AB870_RS03985	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AB870_RS03990	COG0316	Belongs to the HesB IscA family
AB870_RS04005	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AB870_RS04010	COG0739	heme binding
AB870_RS04020	COG1490	D-aminoacyl-tRNA deacylase activity
AB870_RS04025	COG1881	PFAM PEBP family protein
AB870_RS04040	COG2255	four-way junction helicase activity
AB870_RS04045	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AB870_RS04050	COG1981	membrane
AB870_RS04060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AB870_RS04075	COG0800	Aldolase
AB870_RS04085	COG3265	gluconokinase activity
AB870_RS04105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AB870_RS04130	COG0482	sulfurtransferase activity
AB870_RS04135	COG0069	glutamate synthase activity
AB870_RS04140	COG2207	Transcriptional regulator
AB870_RS04205	COG2197	response regulator
AB870_RS04240	COG4790	Type iii secretion
AB870_RS04260	COG0741	lytic transglycosylase activity
AB870_RS04275	COG3909	cytochrome
AB870_RS04295	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AB870_RS04300	COG1862	Preprotein translocase
AB870_RS04305	COG0343	queuine tRNA-ribosyltransferase activity
AB870_RS04315	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AB870_RS04320	COG0583	DNA-binding transcription factor activity
AB870_RS04325	COG0753	catalase activity
AB870_RS04330	COG0352	thiamine-phosphate diphosphorylase activity
AB870_RS04335	COG0783	Belongs to the Dps family
AB870_RS04345	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AB870_RS04365	COG1741	Belongs to the pirin family
AB870_RS04390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AB870_RS04415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB870_RS04430	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AB870_RS04445	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS04460	COG2207	Transcriptional regulator
AB870_RS04465	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AB870_RS04490	COG2205	protein histidine kinase activity
AB870_RS04490	COG0784	Response regulator, receiver
AB870_RS04515	COG0392	lysyltransferase activity
AB870_RS04515	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AB870_RS04560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AB870_RS04570	COG4962	Type ii secretion system protein e
AB870_RS04585	COG2801	Transposase and inactivated derivatives
AB870_RS04670	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AB870_RS04675	COG4566	intracellular signal transduction
AB870_RS04720	COG1297	OPT oligopeptide transporter protein
AB870_RS04730	COG1686	Belongs to the peptidase S11 family
AB870_RS04735	COG1464	Belongs to the NlpA lipoprotein family
AB870_RS04740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AB870_RS04745	COG2011	ABC-type metal ion transport system permease component
AB870_RS04760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB870_RS04770	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AB870_RS04775	COG1845	cytochrome c oxidase, subunit III
AB870_RS04780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AB870_RS04785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AB870_RS04790	COG0477	Major facilitator Superfamily
AB870_RS04795	COG0583	DNA-binding transcription factor activity
AB870_RS04800	COG0444	Belongs to the ABC transporter superfamily
AB870_RS04805	COG4608	Belongs to the ABC transporter superfamily
AB870_RS04815	COG0601	transmembrane transport
AB870_RS04820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB870_RS04830	COG2814	Major facilitator Superfamily
AB870_RS04840	COG0583	DNA-binding transcription factor activity
AB870_RS04845	COG0643	Histidine kinase
AB870_RS04845	COG2198	Histidine kinase
AB870_RS04850	COG0840	transmembrane signaling receptor activity
AB870_RS04875	COG2814	Major facilitator Superfamily
AB870_RS04880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS04885	COG1024	Enoyl-CoA hydratase
AB870_RS04890	COG1012	belongs to the aldehyde dehydrogenase family
AB870_RS04900	COG1960	acyl-CoA dehydrogenase activity
AB870_RS04910	COG0583	DNA-binding transcription factor activity
AB870_RS04915	COG3485	protocatechuate 3,4-dioxygenase
AB870_RS04920	COG3485	protocatechuate 3,4-dioxygenase
AB870_RS04930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AB870_RS04935	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB870_RS04940	COG1917	Cupin 2, conserved barrel domain protein
AB870_RS04940	COG2207	Transcriptional regulator
AB870_RS04950	COG2814	Major facilitator Superfamily
AB870_RS04985	COG0513	Belongs to the DEAD box helicase family
AB870_RS05000	COG3634	alkyl hydroperoxide reductase activity
AB870_RS05010	COG0667	Aldo Keto reductase
AB870_RS05015	COG3284	Transcriptional regulator
AB870_RS05020	COG0583	DNA-binding transcription factor activity
AB870_RS05025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB870_RS05050	COG1609	Transcriptional regulator
AB870_RS05055	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS05060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AB870_RS05075	COG1850	ribulose-bisphosphate carboxylase activity
AB870_RS05085	COG1414	Transcriptional regulator
AB870_RS05090	COG1012	belongs to the aldehyde dehydrogenase family
AB870_RS05095	COG0318	PFAM AMP-dependent synthetase and ligase
AB870_RS05100	COG2271	Major facilitator Superfamily
AB870_RS05105	COG4149	molybdate abc transporter
AB870_RS05115	COG3842	ATPase activity
AB870_RS05120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS05125	COG2205	protein histidine kinase activity
AB870_RS05130	COG0745	RESPONSE REGULATOR receiver
AB870_RS05160	COG0840	transmembrane signaling receptor activity
AB870_RS05175	COG3237	CsbD-like
AB870_RS05210	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AB870_RS05215	COG2011	ABC-type metal ion transport system permease component
AB870_RS05230	COG3300	MHYT domain
AB870_RS05230	COG5001	Diguanylate cyclase
AB870_RS05235	COG0531	amino acid
AB870_RS05245	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AB870_RS05255	COG0436	Aminotransferase
AB870_RS05260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AB870_RS05265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AB870_RS05275	COG0640	Transcriptional regulator
AB870_RS05320	COG3971	2-oxopent-4-enoate hydratase activity
AB870_RS05330	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB870_RS05330	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB870_RS05345	COG1704	LemA family
AB870_RS05350	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AB870_RS05355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AB870_RS05360	COG0671	phosphoesterase, PA-phosphatase related
AB870_RS05370	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AB870_RS05385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB870_RS05400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AB870_RS05410	COG1737	Transcriptional regulator
AB870_RS05410	COG0837	glucose binding
AB870_RS05420	COG3360	Dodecin
AB870_RS05425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AB870_RS05430	COG0443	Heat shock 70 kDa protein
AB870_RS05435	COG2814	Major facilitator Superfamily
AB870_RS05445	COG0640	Transcriptional regulator
AB870_RS05460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB870_RS05475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB870_RS05480	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS05495	COG1414	Transcriptional regulator
AB870_RS05505	COG0028	Belongs to the TPP enzyme family
AB870_RS05515	COG1012	belongs to the aldehyde dehydrogenase family
AB870_RS05520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB870_RS05555	COG0386	Belongs to the glutathione peroxidase family
AB870_RS05560	COG2207	Transcriptional regulator
AB870_RS05565	COG4638	Rieske (2fe-2S)
AB870_RS05570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB870_RS05600	COG2072	flavoprotein involved in K transport
AB870_RS05690	COG0583	DNA-binding transcription factor activity
AB870_RS05695	COG0730	response to heat
AB870_RS05700	COG0175	sulfate reduction
AB870_RS05710	COG2895	sulfate adenylyltransferase (ATP) activity
AB870_RS05740	COG0795	lipopolysaccharide-transporting ATPase activity
AB870_RS05745	COG0795	lipopolysaccharide-transporting ATPase activity
AB870_RS05750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AB870_RS05775	COG0129	dihydroxy-acid dehydratase activity
AB870_RS05780	COG0583	DNA-binding transcription factor activity
AB870_RS05785	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AB870_RS05790	COG1802	Transcriptional regulator
AB870_RS05795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AB870_RS05815	COG1024	Enoyl-CoA hydratase
AB870_RS05820	COG0318	PFAM AMP-dependent synthetase and ligase
AB870_RS05855	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AB870_RS05865	COG0287	Prephenate dehydrogenase
AB870_RS05870	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AB870_RS05875	COG1914	H( )-stimulated, divalent metal cation uptake system
AB870_RS05880	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AB870_RS05900	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AB870_RS05910	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AB870_RS05930	COG2951	lytic endotransglycosylase activity
AB870_RS05935	COG0123	including yeast histone deacetylase and acetoin utilization protein
AB870_RS05965	COG1960	acyl-CoA dehydrogenase activity
AB870_RS05985	COG4206	TonB-dependent receptor
AB870_RS05990	COG4139	cobalamin transport
AB870_RS05995	COG1120	ATPase activity
AB870_RS06000	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AB870_RS06005	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AB870_RS06015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AB870_RS06030	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AB870_RS06040	COG1492	cobalamin metabolic process
AB870_RS06045	COG0489	protein tyrosine kinase activity
AB870_RS06050	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AB870_RS06055	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AB870_RS06075	COG2911	Protein conserved in bacteria
AB870_RS06090	COG1522	sequence-specific DNA binding
AB870_RS06100	COG2885	chlorophyll binding
AB870_RS06105	COG0489	protein tyrosine kinase activity
AB870_RS06110	COG0717	Belongs to the dCTP deaminase family
AB870_RS06120	COG0786	glutamate:sodium symporter activity
AB870_RS06125	COG0165	Argininosuccinate lyase
AB870_RS06140	COG0181	hydroxymethylbilane synthase activity
AB870_RS06160	COG0477	Major facilitator Superfamily
AB870_RS06165	COG2271	Major facilitator Superfamily
AB870_RS06180	COG0277	FAD linked oxidase domain protein
AB870_RS06200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB870_RS06215	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AB870_RS06225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AB870_RS06225	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AB870_RS06235	COG2860	membrane
AB870_RS06240	COG1193	negative regulation of DNA recombination
AB870_RS06245	COG0492	ferredoxin-NADP+ reductase activity
AB870_RS06250	COG1674	ftsk spoiiie
AB870_RS06255	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AB870_RS06260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AB870_RS06265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AB870_RS06290	COG1002	Type II restriction enzyme, methylase subunits
AB870_RS06315	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AB870_RS06320	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AB870_RS06330	COG1819	glycosyl
AB870_RS06345	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AB870_RS06350	COG3119	arylsulfatase activity
AB870_RS06360	COG0714	Associated with various cellular activities
AB870_RS06410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB870_RS06430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AB870_RS06440	COG1473	amidohydrolase
AB870_RS06460	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AB870_RS06465	COG0235	Class ii aldolase
AB870_RS06475	COG2271	Major facilitator Superfamily
AB870_RS06485	COG2860	membrane
AB870_RS06490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB870_RS06500	COG1538	Outer membrane efflux protein
AB870_RS06515	COG0745	RESPONSE REGULATOR receiver
AB870_RS06535	COG1562	ergosterol biosynthetic process
AB870_RS06540	COG1562	ergosterol biosynthetic process
AB870_RS06545	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AB870_RS06550	COG1657	PFAM Prenyltransferase squalene oxidase
AB870_RS06560	COG0463	Glycosyl transferase, family 2
AB870_RS06565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB870_RS06570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AB870_RS06590	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AB870_RS06595	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AB870_RS06600	COG0028	Belongs to the TPP enzyme family
AB870_RS06600	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
AB870_RS06610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AB870_RS06625	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS06640	COG2375	cellular response to nickel ion
AB870_RS06645	COG1695	Transcriptional regulator
AB870_RS06650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB870_RS06675	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AB870_RS06680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AB870_RS06685	COG1414	Transcriptional regulator
AB870_RS06700	COG0798	PFAM Bile acid sodium symporter
AB870_RS06715	COG0004	ammonium transporteR
AB870_RS06725	COG2186	Transcriptional regulator
AB870_RS06730	COG0277	FAD linked oxidase domain protein
AB870_RS06740	COG2814	Major facilitator Superfamily
AB870_RS06755	COG0579	oxidoreductase
AB870_RS06765	COG1414	Transcriptional regulator
AB870_RS06770	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS06775	COG2271	Major facilitator Superfamily
AB870_RS06790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB870_RS06795	COG1960	acyl-CoA dehydrogenase activity
AB870_RS06800	COG1024	Enoyl-CoA hydratase
AB870_RS06820	COG1446	asparaginase
AB870_RS06825	COG4172	Belongs to the ABC transporter superfamily
AB870_RS06840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB870_RS06865	COG3842	ATPase activity
AB870_RS06870	COG1653	transport
AB870_RS06875	COG1175	transmembrane transport
AB870_RS06885	COG0589	response to stress
AB870_RS06905	COG0534	Mate efflux family protein
AB870_RS06915	COG2985	domain, Protein
AB870_RS06920	COG2985	domain, Protein
AB870_RS06950	COG3383	formate dehydrogenase (NAD+) activity
AB870_RS06960	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AB870_RS06965	COG1802	Transcriptional regulator
AB870_RS06975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AB870_RS07020	COG4191	Histidine kinase
AB870_RS07025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB870_RS07030	COG0179	Fumarylacetoacetate (FAA) hydrolase
AB870_RS07040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AB870_RS07060	COG0583	DNA-binding transcription factor activity
AB870_RS07075	COG1802	Transcriptional regulator
AB870_RS07090	COG1024	Enoyl-CoA hydratase
AB870_RS07095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB870_RS07100	COG3387	PFAM Glycoside hydrolase 15-related
AB870_RS07110	COG2814	Major facilitator Superfamily
AB870_RS07125	COG3008	intermembrane lipid transfer
AB870_RS07130	COG2995	paraquat-inducible protein a
AB870_RS07140	COG0243	molybdopterin cofactor binding
AB870_RS07140	COG3383	formate dehydrogenase (NAD+) activity
AB870_RS07150	COG0437	4 iron, 4 sulfur cluster binding
AB870_RS07155	COG2864	formate dehydrogenase
AB870_RS07200	COG2814	Major facilitator Superfamily
AB870_RS07205	COG3384	dioxygenase
AB870_RS07210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AB870_RS07215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AB870_RS07215	COG0473	3-isopropylmalate dehydrogenase activity
AB870_RS07220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AB870_RS07230	COG0523	cobalamin synthesis protein
AB870_RS07235	COG4638	Rieske (2fe-2S)
AB870_RS07240	COG3384	dioxygenase
AB870_RS07250	COG2159	amidohydrolase
AB870_RS07270	COG0583	DNA-binding transcription factor activity
AB870_RS07280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AB870_RS07300	COG1959	2 iron, 2 sulfur cluster binding
AB870_RS07315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS07320	COG0584	glycerophosphoryl diester phosphodiesterase
AB870_RS07325	COG1349	DNA-binding transcription factor activity
AB870_RS07330	COG0583	DNA-binding transcription factor activity
AB870_RS07340	COG2814	Major facilitator Superfamily
AB870_RS07375	COG2391	methyltransferase activity
AB870_RS07390	COG0823	Involved in the tonB-independent uptake of proteins
AB870_RS07400	COG0848	biopolymer transport protein
AB870_RS07410	COG0824	Thioesterase
AB870_RS07415	COG2084	Dehydrogenase
AB870_RS07420	COG1414	Transcriptional regulator
AB870_RS07460	COG2808	Putative FMN-binding domain
AB870_RS07495	COG0543	2 iron, 2 sulfur cluster binding
AB870_RS07500	COG2814	Major facilitator Superfamily
AB870_RS07540	COG2814	Major facilitator Superfamily
AB870_RS07545	COG0583	DNA-binding transcription factor activity
AB870_RS07585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AB870_RS07590	COG0686	Belongs to the AlaDH PNT family
AB870_RS07595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB870_RS07630	COG0228	four-way junction DNA binding
AB870_RS07635	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AB870_RS07640	COG0336	Belongs to the RNA methyltransferase TrmD family
AB870_RS07645	COG0335	large ribosomal subunit rRNA binding
AB870_RS07650	COG0494	nUDIX hydrolase
AB870_RS07655	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AB870_RS07665	COG1162	GTPase activity
AB870_RS07670	COG0501	Belongs to the peptidase M48B family
AB870_RS07675	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AB870_RS07680	COG0521	Mo-molybdopterin cofactor biosynthetic process
AB870_RS07690	COG0312	modulator of DNA gyrase
AB870_RS07700	COG0559	Belongs to the binding-protein-dependent transport system permease family
AB870_RS07720	COG5001	Diguanylate cyclase
AB870_RS07720	COG4251	negative regulation of phosphorylation
AB870_RS07720	COG3706	GGDEF domain
AB870_RS07720	COG2203	Gaf domain
AB870_RS07730	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AB870_RS07735	COG3842	ATPase activity
AB870_RS07740	COG1178	ABC-type Fe3 transport system permease component
AB870_RS07745	COG0583	DNA-binding transcription factor activity
AB870_RS07755	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AB870_RS07760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB870_RS07765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB870_RS07775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AB870_RS07780	COG1285	pathogenesis
AB870_RS07790	COG0415	Belongs to the DNA photolyase family
AB870_RS07800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB870_RS07820	COG2153	protein acetylation
AB870_RS07825	COG0488	(ABC) transporter
AB870_RS07840	COG0741	lytic transglycosylase activity
AB870_RS07840	COG0739	heme binding
AB870_RS07840	COG1196	nuclear chromosome segregation
AB870_RS07855	COG0583	DNA-binding transcription factor activity
AB870_RS07860	COG2814	Major facilitator Superfamily
AB870_RS07870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB870_RS07875	COG0697	spore germination
AB870_RS07900	COG3161	chorismate lyase activity
AB870_RS07920	COG3135	benzoate transporter
AB870_RS07930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AB870_RS07955	COG0778	Nitroreductase
AB870_RS07960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AB870_RS07965	COG2878	Part of a membrane complex involved in electron transport
AB870_RS07970	COG1309	transcriptional regulator
AB870_RS07985	COG0556	nucleotide-excision repair
AB870_RS07990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AB870_RS08005	COG1104	cysteine desulfurase activity
AB870_RS08010	COG0822	iron-sulfur transferase activity
AB870_RS08015	COG0316	Belongs to the HesB IscA family
AB870_RS08020	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AB870_RS08035	COG2975	iron-sulfur cluster assembly
AB870_RS08060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AB870_RS08070	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AB870_RS08085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AB870_RS08110	COG0084	hydrolase, TatD family'
AB870_RS08120	COG2267	carboxylic ester hydrolase activity
AB870_RS08125	COG0504	CTP synthase activity
AB870_RS08130	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AB870_RS08135	COG0148	phosphopyruvate hydratase activity
AB870_RS08140	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AB870_RS08150	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AB870_RS08160	COG2833	Protein of unknown function (DUF455)
AB870_RS08165	COG2267	carboxylic ester hydrolase activity
AB870_RS08170	COG0613	PHP domain protein
AB870_RS08175	COG0009	L-threonylcarbamoyladenylate synthase
AB870_RS08180	COG1994	Peptidase M50
AB870_RS08185	COG0180	Tryptophanyl-tRNA synthetase
AB870_RS08195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB870_RS08200	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AB870_RS08205	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AB870_RS08205	COG0321	lipoyl(octanoyl) transferase activity
AB870_RS08210	COG2850	peptidyl-arginine hydroxylation
AB870_RS08230	COG5001	Diguanylate cyclase
AB870_RS08230	COG3447	MASE1 domain protein
AB870_RS08230	COG5002	protein histidine kinase activity
AB870_RS08245	COG0149	triose-phosphate isomerase activity
AB870_RS08260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB870_RS08275	COG0649	NAD binding
AB870_RS08280	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AB870_RS08290	COG1034	ATP synthesis coupled electron transport
AB870_RS08295	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AB870_RS08300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB870_RS08310	COG0713	ATP synthesis coupled electron transport
AB870_RS08325	COG1007	ATP synthesis coupled electron transport
AB870_RS08365	COG0625	glutathione transferase activity
AB870_RS08370	COG1960	acyl-CoA dehydrogenase activity
AB870_RS08380	COG0588	phosphoglycerate mutase activity
AB870_RS08385	COG1024	Enoyl-CoA hydratase
AB870_RS08390	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB870_RS08400	COG0625	glutathione transferase activity
AB870_RS08405	COG0436	Aminotransferase
AB870_RS08415	COG3022	response to hydroperoxide
AB870_RS08420	COG2866	Carboxypeptidase
AB870_RS08430	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AB870_RS08450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AB870_RS08460	COG0039	L-malate dehydrogenase activity
AB870_RS08465	COG2188	Transcriptional regulator
AB870_RS08480	COG1053	succinate dehydrogenase
AB870_RS08485	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AB870_RS08490	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AB870_RS08495	COG0372	Belongs to the citrate synthase family
AB870_RS08500	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AB870_RS08510	COG0066	3-isopropylmalate dehydratase activity
AB870_RS08515	COG0473	3-isopropylmalate dehydrogenase activity
AB870_RS08520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AB870_RS08530	COG0101	tRNA pseudouridine synthase activity
AB870_RS08535	COG0135	phosphoribosylanthranilate isomerase activity
AB870_RS08540	COG0133	tryptophan synthase activity
AB870_RS08550	COG0159	tryptophan synthase activity
AB870_RS08555	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AB870_RS08560	COG0285	dihydrofolate synthase activity
AB870_RS08585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AB870_RS08595	COG2194	sulfuric ester hydrolase activity
AB870_RS08600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB870_RS08600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB870_RS08610	COG0431	NADPH-dependent FMN reductase
AB870_RS08615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB870_RS08620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB870_RS08625	COG1116	anion transmembrane transporter activity
AB870_RS08635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB870_RS08640	COG0483	inositol monophosphate 1-phosphatase activity
AB870_RS08650	COG1045	serine acetyltransferase
AB870_RS08655	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AB870_RS08680	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AB870_RS08690	COG0037	tRNA processing
AB870_RS08695	COG0527	aspartate kinase activity
AB870_RS08725	COG4166	transmembrane transport
AB870_RS08730	COG4174	ABC transporter (Permease)
AB870_RS08735	COG4239	(ABC) transporter, permease
AB870_RS08740	COG4172	Belongs to the ABC transporter superfamily
AB870_RS08745	COG0791	NLP P60 protein
AB870_RS08750	COG1752	Esterase of the alpha-beta hydrolase superfamily
AB870_RS08755	COG1840	ABC-type Fe3 transport system, periplasmic component
AB870_RS08765	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AB870_RS08785	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AB870_RS08795	COG2204	response regulator
AB870_RS08840	COG2197	response regulator
AB870_RS08845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB870_RS08860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB870_RS08865	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AB870_RS08870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AB870_RS08900	COG0105	UTP biosynthetic process
AB870_RS08905	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AB870_RS08915	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AB870_RS08920	COG0124	histidyl-tRNA synthetase
AB870_RS08925	COG2976	Protein conserved in bacteria
AB870_RS08935	COG1160	GTP binding
AB870_RS08940	COG1923	regulation of RNA biosynthetic process
AB870_RS08945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AB870_RS08950	COG0330	HflC and HflK could
AB870_RS08955	COG0330	HflC and HflK could
AB870_RS08960	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AB870_RS08965	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AB870_RS08970	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AB870_RS08975	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AB870_RS08990	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AB870_RS09005	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AB870_RS09010	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB870_RS09020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB870_RS09030	COG0123	including yeast histone deacetylase and acetoin utilization protein
AB870_RS09035	COG0697	spore germination
AB870_RS09045	COG1686	Belongs to the peptidase S11 family
AB870_RS09050	COG1414	Transcriptional regulator
AB870_RS09070	COG1139	Iron-sulfur cluster binding protein
AB870_RS09075	COG0765	amino acid transport
AB870_RS09080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB870_RS09085	COG0167	dihydroorotate dehydrogenase activity
AB870_RS09090	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AB870_RS09120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AB870_RS09130	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AB870_RS09165	COG2267	carboxylic ester hydrolase activity
AB870_RS09185	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AB870_RS09190	COG1278	Cold shock
AB870_RS09200	COG0679	Auxin Efflux Carrier
AB870_RS09225	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AB870_RS09230	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AB870_RS09235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AB870_RS09240	COG0840	transmembrane signaling receptor activity
AB870_RS09295	COG1280	lysine exporter protein (LysE YggA)
AB870_RS09305	COG0174	glutamine synthetase
AB870_RS09315	COG2204	response regulator
AB870_RS09340	COG0307	riboflavin synthase, alpha
AB870_RS09355	COG0387	Pfam Sodium calcium exchanger
AB870_RS09360	COG2186	Transcriptional regulator
AB870_RS09365	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS09375	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS09380	COG2818	Glycosylase
AB870_RS09385	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AB870_RS09390	COG1187	pseudouridine synthase activity
AB870_RS09395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB870_RS09400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB870_RS09405	COG1116	anion transmembrane transporter activity
AB870_RS09420	COG2207	Transcriptional regulator
AB870_RS09430	COG0583	DNA-binding transcription factor activity
AB870_RS09450	COG0557	exoribonuclease II activity
AB870_RS09455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB870_RS09475	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AB870_RS09485	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AB870_RS09490	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AB870_RS09490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AB870_RS09495	COG1643	Atp-dependent helicase
AB870_RS09510	COG1546	Belongs to the CinA family
AB870_RS09510	COG1058	Belongs to the CinA family
AB870_RS09520	COG0583	DNA-binding transcription factor activity
AB870_RS09530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB870_RS09535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AB870_RS09540	COG1187	pseudouridine synthase activity
AB870_RS09545	COG0779	Required for maturation of 30S ribosomal subunits
AB870_RS09550	COG0195	Participates in both transcription termination and antitermination
AB870_RS09550	COG2251	uridine kinase activity
AB870_RS09555	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AB870_RS09560	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AB870_RS09565	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AB870_RS09585	COG2814	Major facilitator Superfamily
AB870_RS09590	COG1566	PFAM secretion protein HlyD family protein
AB870_RS09615	COG1024	Enoyl-CoA hydratase
AB870_RS09635	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AB870_RS09640	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AB870_RS09645	COG4208	sulfate ABC transporter
AB870_RS09650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AB870_RS09655	COG0583	DNA-binding transcription factor activity
AB870_RS09660	COG0252	asparaginase activity
AB870_RS09665	COG2084	Dehydrogenase
AB870_RS09670	COG3622	Belongs to the hyi family
AB870_RS09675	COG3960	tartronate-semialdehyde synthase activity
AB870_RS09680	COG0583	DNA-binding transcription factor activity
AB870_RS09700	COG0359	binds to the 23S rRNA
AB870_RS09715	COG0306	phosphate transporter
AB870_RS09720	COG0791	NLP P60 protein
AB870_RS09725	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AB870_RS09730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AB870_RS09740	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AB870_RS09740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB870_RS09755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AB870_RS09760	COG2076	Multidrug Resistance protein
AB870_RS09765	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AB870_RS09775	COG0436	Aminotransferase
AB870_RS09795	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AB870_RS09800	COG0314	molybdopterin synthase activity
AB870_RS09810	COG0542	response to heat
AB870_RS09820	COG3275	phosphorelay sensor kinase activity
AB870_RS09845	COG2224	Isocitrate lyase
AB870_RS09855	COG0583	DNA-binding transcription factor activity
AB870_RS09860	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AB870_RS09870	COG0513	Belongs to the DEAD box helicase family
AB870_RS09875	COG1214	PFAM Peptidase M22, glycoprotease
AB870_RS09880	COG0456	acetyltransferase
AB870_RS09880	COG1214	PFAM Peptidase M22, glycoprotease
AB870_RS09885	COG1573	uracil-dna glycosylase
AB870_RS09895	COG0351	phosphomethylpyrimidine kinase
AB870_RS09900	COG0477	Major facilitator Superfamily
AB870_RS09905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AB870_RS09915	COG0488	(ABC) transporter
AB870_RS09925	COG2890	protein-(glutamine-N5) methyltransferase activity
AB870_RS09930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AB870_RS09935	COG1393	Belongs to the ArsC family
AB870_RS09940	COG2171	N-acyltransferase activity
AB870_RS09965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AB870_RS09970	COG0242	peptide deformylase activity
AB870_RS09975	COG1187	pseudouridine synthase activity
AB870_RS09985	COG0024	Methionine aminopeptidase
AB870_RS09990	COG0052	Belongs to the universal ribosomal protein uS2 family
AB870_RS09995	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AB870_RS10010	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AB870_RS10020	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AB870_RS10025	COG0750	zinc metalloprotease
AB870_RS10040	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AB870_RS10065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB870_RS10070	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AB870_RS10090	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AB870_RS10095	COG2867	negative regulation of translational initiation
AB870_RS10100	COG2914	Belongs to the UPF0125 (RnfH) family
AB870_RS10125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AB870_RS10125	COG0519	Catalyzes the synthesis of GMP from XMP
AB870_RS10130	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS10140	COG0583	DNA-binding transcription factor activity
AB870_RS10170	COG0559	Belongs to the binding-protein-dependent transport system permease family
AB870_RS10175	COG0683	leucine binding
AB870_RS10190	COG1619	proteins homologs of microcin C7 resistance protein MccF
AB870_RS10205	COG4266	Belongs to the allantoicase family
AB870_RS10240	COG2233	PERMEase
AB870_RS10250	COG0583	DNA-binding transcription factor activity
AB870_RS10255	COG3845	ABC transporter
AB870_RS10260	COG4603	Belongs to the binding-protein-dependent transport system permease family
AB870_RS10265	COG1079	Belongs to the binding-protein-dependent transport system permease family
AB870_RS10275	COG0488	(ABC) transporter
AB870_RS10300	COG3706	GGDEF domain
AB870_RS10310	COG0446	pyridine nucleotide-disulphide oxidoreductase
AB870_RS10335	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AB870_RS10350	COG4774	siderophore transport
AB870_RS10380	COG0243	molybdopterin cofactor binding
AB870_RS10400	COG3383	formate dehydrogenase (NAD+) activity
AB870_RS10405	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AB870_RS10430	COG0733	neurotransmitter:sodium symporter activity
AB870_RS10445	COG0471	metal ion transport
AB870_RS10450	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AB870_RS10455	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AB870_RS10490	COG1024	Enoyl-CoA hydratase
AB870_RS10500	COG3842	ATPase activity
AB870_RS10505	COG1176	ABC-type spermidine putrescine transport system, permease component I
AB870_RS10510	COG0318	PFAM AMP-dependent synthetase and ligase
AB870_RS10520	COG3706	GGDEF domain
AB870_RS10535	COG2814	Major facilitator Superfamily
AB870_RS10550	COG5002	protein histidine kinase activity
AB870_RS10550	COG5001	Diguanylate cyclase
AB870_RS10560	COG1674	ftsk spoiiie
AB870_RS10585	COG2070	2-Nitropropane dioxygenase
AB870_RS10590	COG2070	2-Nitropropane dioxygenase
AB870_RS10635	COG4251	negative regulation of phosphorylation
AB870_RS10635	COG2203	Gaf domain
AB870_RS10635	COG3706	GGDEF domain
AB870_RS10635	COG5001	Diguanylate cyclase
AB870_RS10645	COG2823	Periplasmic or secreted lipoprotein
AB870_RS10665	COG4572	Cation transport regulator
AB870_RS10670	COG2814	Major facilitator Superfamily
AB870_RS10675	COG0534	Mate efflux family protein
AB870_RS10685	COG3550	peptidyl-serine autophosphorylation
AB870_RS10730	COG1538	Outer membrane efflux protein
AB870_RS10745	COG2837	iron assimilation
AB870_RS10780	COG3119	arylsulfatase activity
AB870_RS10800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AB870_RS10820	COG0446	pyridine nucleotide-disulphide oxidoreductase
AB870_RS10820	COG1902	pentaerythritol trinitrate reductase activity
AB870_RS10830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB870_RS10835	COG0372	Belongs to the citrate synthase family
AB870_RS10875	COG0662	Cupin 2, conserved barrel domain protein
AB870_RS10885	COG0625	glutathione transferase activity
AB870_RS10895	COG3468	outer membrane autotransporter barrel domain protein
AB870_RS10905	COG1802	Transcriptional regulator
AB870_RS10915	COG1454	alcohol dehydrogenase
AB870_RS10920	COG0477	Major facilitator Superfamily
AB870_RS10935	COG1595	DNA-templated transcription, initiation
AB870_RS10955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB870_RS10975	COG1960	acyl-CoA dehydrogenase activity
AB870_RS10985	COG4608	Belongs to the ABC transporter superfamily
AB870_RS10990	COG0444	Belongs to the ABC transporter superfamily
AB870_RS10995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB870_RS11005	COG0318	PFAM AMP-dependent synthetase and ligase
AB870_RS11015	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS11020	COG1053	succinate dehydrogenase
AB870_RS11025	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AB870_RS11030	COG0747	negative chemotaxis
AB870_RS11040	COG1024	Enoyl-CoA hydratase
AB870_RS11050	COG0439	Biotin carboxylase
AB870_RS11055	COG0366	Alpha amylase catalytic
AB870_RS11065	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AB870_RS11075	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AB870_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS11120	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS11125	COG0297	glycogen (starch) synthase activity
AB870_RS11130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB870_RS11135	COG0028	Belongs to the TPP enzyme family
AB870_RS11140	COG2205	protein histidine kinase activity
AB870_RS11140	COG2198	Histidine kinase
AB870_RS11140	COG0784	Response regulator, receiver
AB870_RS11155	COG2204	response regulator
AB870_RS11160	COG2204	response regulator
AB870_RS11165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AB870_RS11180	COG2192	nodulation
AB870_RS11185	COG0859	PFAM glycosyl transferase family 9
AB870_RS11190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AB870_RS11195	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS11205	COG5265	(ABC) transporter
AB870_RS11210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AB870_RS11220	COG0252	asparaginase activity
AB870_RS11245	COG1335	isochorismatase
AB870_RS11340	COG1132	(ABC) transporter
AB870_RS11350	COG2059	Chromate
AB870_RS11360	COG1045	serine acetyltransferase
AB870_RS11370	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AB870_RS11375	COG1181	Belongs to the D-alanine--D-alanine ligase family
AB870_RS11390	COG0583	DNA-binding transcription factor activity
AB870_RS11395	COG3493	citrate carrier protein
AB870_RS11405	COG2301	Belongs to the HpcH HpaI aldolase family
AB870_RS11415	COG0840	transmembrane signaling receptor activity
AB870_RS11420	COG0688	phosphatidylethanolamine metabolic process
AB870_RS11425	COG0583	DNA-binding transcription factor activity
AB870_RS11430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AB870_RS11450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB870_RS11455	COG2188	Transcriptional regulator
AB870_RS11465	COG2986	histidine ammonia-lyase
AB870_RS11470	COG1113	amino acid transport
AB870_RS11480	COG0010	Belongs to the arginase family
AB870_RS11485	COG0583	DNA-binding transcription factor activity
AB870_RS11495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB870_RS11510	COG3791	Glutathione-dependent formaldehyde-activating
AB870_RS11530	COG0477	Major facilitator Superfamily
AB870_RS11535	COG1113	amino acid transport
AB870_RS11545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB870_RS11550	COG0657	acetylesterase activity
AB870_RS11560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB870_RS11580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AB870_RS11625	COG3257	ureidoglycine aminohydrolase activity
AB870_RS11630	COG0583	DNA-binding transcription factor activity
AB870_RS11645	COG0402	S-adenosylhomocysteine deaminase activity
AB870_RS11655	COG2197	response regulator
AB870_RS11675	COG0583	DNA-binding transcription factor activity
AB870_RS11695	COG2814	Major facilitator Superfamily
AB870_RS11700	COG1022	Amp-dependent synthetase and ligase
AB870_RS11710	COG3246	L-lysine catabolic process to acetate
AB870_RS11715	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB870_RS11720	COG1024	Enoyl-CoA hydratase
AB870_RS11725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AB870_RS11735	COG3712	iron ion homeostasis
AB870_RS11765	COG5002	protein histidine kinase activity
AB870_RS11765	COG5001	Diguanylate cyclase
AB870_RS11765	COG3447	MASE1 domain protein
AB870_RS11780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB870_RS11790	COG2204	response regulator
AB870_RS11810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB870_RS11815	COG0840	transmembrane signaling receptor activity
AB870_RS11845	COG0583	DNA-binding transcription factor activity
AB870_RS11860	COG4106	trans-aconitate 2-methyltransferase activity
AB870_RS11885	COG0739	heme binding
AB870_RS11890	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AB870_RS11890	COG2755	lipolytic protein G-D-S-L family
AB870_RS11900	COG3243	poly(R)-hydroxyalkanoic acid synthase
AB870_RS11910	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS11915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB870_RS11920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB870_RS11945	COG0667	Aldo Keto reductase
AB870_RS11950	COG2194	sulfuric ester hydrolase activity
AB870_RS11955	COG1215	transferase activity, transferring glycosyl groups
AB870_RS11965	COG0457	Tetratricopeptide repeat
AB870_RS11970	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AB870_RS11975	COG1215	transferase activity, transferring glycosyl groups
AB870_RS11995	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AB870_RS12005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AB870_RS12035	COG1012	belongs to the aldehyde dehydrogenase family
AB870_RS12050	COG0628	permease
AB870_RS12065	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AB870_RS12075	COG0784	Response regulator, receiver
AB870_RS12075	COG2205	protein histidine kinase activity
AB870_RS12080	COG2197	response regulator
AB870_RS12090	COG0730	response to heat
AB870_RS12095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB870_RS12100	COG0598	Magnesium transport protein CorA
AB870_RS12105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AB870_RS12105	COG1042	CoA-binding domain protein
AB870_RS12105	COG0045	succinate-CoA ligase (ADP-forming) activity
AB870_RS12110	COG0783	Belongs to the Dps family
AB870_RS12155	COG0765	amino acid transport
AB870_RS12165	COG0028	Belongs to the TPP enzyme family
AB870_RS12170	COG1522	sequence-specific DNA binding
AB870_RS12180	COG1272	protein, Hemolysin III
AB870_RS12185	COG2205	protein histidine kinase activity
AB870_RS12190	COG0840	transmembrane signaling receptor activity
AB870_RS12195	COG1254	Belongs to the acylphosphatase family
AB870_RS12210	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AB870_RS12225	COG0084	hydrolase, TatD family'
AB870_RS12235	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AB870_RS12240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AB870_RS12260	COG2130	NADP-dependent
AB870_RS12270	COG1335	isochorismatase
AB870_RS12300	COG0318	PFAM AMP-dependent synthetase and ligase
AB870_RS12305	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AB870_RS12310	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AB870_RS12320	COG2917	probably involved in intracellular septation
AB870_RS12330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB870_RS12335	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AB870_RS12335	COG0047	phosphoribosylformylglycinamidine synthase activity
AB870_RS12340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB870_RS12345	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AB870_RS12345	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AB870_RS12355	COG4181	ATPase activity
AB870_RS12370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB870_RS12385	COG0776	regulation of translation
AB870_RS12390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AB870_RS12400	COG0740	serine-type endopeptidase activity
AB870_RS12405	COG0544	peptidyl-prolyl cis-trans isomerase activity
AB870_RS12420	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS12435	COG0318	PFAM AMP-dependent synthetase and ligase
AB870_RS12445	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AB870_RS12455	COG0850	regulation of cytokinetic process
AB870_RS12475	COG0583	DNA-binding transcription factor activity
AB870_RS12480	COG2974	May be involved in recombination
AB870_RS12490	COG1132	(ABC) transporter
AB870_RS12500	COG1181	Belongs to the D-alanine--D-alanine ligase family
AB870_RS12500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AB870_RS12515	COG0583	DNA-binding transcription factor activity
AB870_RS12520	COG0657	acetylesterase activity
AB870_RS12555	COG0024	Methionine aminopeptidase
AB870_RS12570	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB870_RS12675	COG0450	alkyl hydroperoxide reductase
AB870_RS12680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AB870_RS12685	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AB870_RS12690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AB870_RS12695	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AB870_RS12725	COG4977	sequence-specific DNA binding
AB870_RS12735	COG0560	Phosphoserine phosphatase
AB870_RS12740	COG0626	cystathionine gamma-synthase activity
AB870_RS12745	COG0183	Belongs to the thiolase family
AB870_RS12750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AB870_RS12755	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AB870_RS12765	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS12770	COG0183	Belongs to the thiolase family
AB870_RS12775	COG3243	poly(R)-hydroxyalkanoic acid synthase
AB870_RS12795	COG0564	pseudouridine synthase activity
AB870_RS12805	COG0505	Belongs to the CarA family
AB870_RS12810	COG1199	ATP-dependent helicase activity
AB870_RS12825	COG2183	response to ionizing radiation
AB870_RS12830	COG3158	transport of potassium into the cell
AB870_RS12880	COG4964	Belongs to the GSP D family
AB870_RS12925	COG1846	Transcriptional regulator
AB870_RS12955	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AB870_RS12960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB870_RS12965	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB870_RS12970	COG0567	Dehydrogenase, E1 component
AB870_RS12975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AB870_RS12980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB870_RS12990	COG0840	transmembrane signaling receptor activity
AB870_RS13035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB870_RS13050	COG3685	Protein conserved in bacteria
AB870_RS13075	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB870_RS13095	COG4251	negative regulation of phosphorylation
AB870_RS13095	COG2203	Gaf domain
AB870_RS13095	COG5001	Diguanylate cyclase
AB870_RS13095	COG3706	GGDEF domain
AB870_RS13105	COG2200	EAL domain
AB870_RS13115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB870_RS13130	COG1177	transmembrane transport
AB870_RS13140	COG3842	ATPase activity
AB870_RS13150	COG3706	GGDEF domain
AB870_RS13160	COG2501	S4 domain
AB870_RS13165	COG2200	EAL domain
AB870_RS13165	COG2202	Pas domain
AB870_RS13165	COG2199	diguanylate cyclase activity
AB870_RS13185	COG1773	rubredoxin
AB870_RS13200	COG5001	Diguanylate cyclase
AB870_RS13200	COG3300	MHYT domain
AB870_RS13210	COG0776	regulation of translation
AB870_RS13225	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AB870_RS13235	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AB870_RS13240	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AB870_RS13250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AB870_RS13255	COG0251	oxidation-reduction process
AB870_RS13265	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS13280	COG2197	response regulator
AB870_RS13295	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS13320	COG0477	Major facilitator Superfamily
AB870_RS13335	COG0596	Alpha beta hydrolase
AB870_RS13345	COG1295	ribonuclease BN
AB870_RS13360	COG0277	FAD linked oxidase domain protein
AB870_RS13395	COG0534	Mate efflux family protein
AB870_RS13430	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AB870_RS13450	COG1652	LysM domain
AB870_RS13455	COG1183	phosphatidylcholine synthase activity
AB870_RS13460	COG0688	phosphatidylethanolamine metabolic process
AB870_RS13465	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AB870_RS13475	COG0028	Belongs to the TPP enzyme family
AB870_RS13510	COG0438	transferase activity, transferring glycosyl groups
AB870_RS13520	COG1309	transcriptional regulator
AB870_RS13540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AB870_RS13555	COG2346	COG2346, Truncated hemoglobins
AB870_RS13560	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AB870_RS13575	COG0745	RESPONSE REGULATOR receiver
AB870_RS13580	COG2205	protein histidine kinase activity
AB870_RS13585	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AB870_RS13590	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AB870_RS13595	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AB870_RS13630	COG3118	belongs to the thioredoxin family
AB870_RS13635	COG0475	glutathione-regulated potassium exporter activity
AB870_RS13640	COG1741	Belongs to the pirin family
AB870_RS13650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AB870_RS13665	COG1561	YicC-like family, N-terminal region
AB870_RS13675	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AB870_RS13680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AB870_RS13685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB870_RS13790	COG1176	ABC-type spermidine putrescine transport system, permease component I
AB870_RS13795	COG3842	ATPase activity
AB870_RS13805	COG0583	DNA-binding transcription factor activity
AB870_RS13830	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AB870_RS13840	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AB870_RS13855	COG2223	nitrite transmembrane transporter activity
AB870_RS13870	COG1271	oxidase subunit
AB870_RS13875	COG1294	oxidase, subunit
AB870_RS13885	COG0302	gtp cyclohydrolase
AB870_RS13890	COG0583	DNA-binding transcription factor activity
AB870_RS13905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AB870_RS13925	COG1929	Belongs to the glycerate kinase type-1 family
AB870_RS13940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AB870_RS13980	COG4221	oxidoreductase activity
AB870_RS13990	COG0583	DNA-binding transcription factor activity
AB870_RS13995	COG2271	Major facilitator Superfamily
AB870_RS14005	COG0129	dihydroxy-acid dehydratase activity
AB870_RS14015	COG0747	negative chemotaxis
AB870_RS14035	COG2814	Major facilitator Superfamily
AB870_RS14040	COG2814	Major facilitator Superfamily
AB870_RS14050	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AB870_RS14060	COG0583	DNA-binding transcription factor activity
AB870_RS14065	COG0427	acetyl-CoA hydrolase
AB870_RS14070	COG0840	transmembrane signaling receptor activity
AB870_RS14080	COG0840	transmembrane signaling receptor activity
AB870_RS14200	COG4386	tail sheath protein
AB870_RS14355	COG2974	May be involved in recombination
AB870_RS14365	COG0592	DNA-directed DNA polymerase activity
AB870_RS14405	COG0582	viral genome integration into host DNA
AB870_RS14430	COG1610	YqeY-like protein
AB870_RS14435	COG2081	HI0933 family
AB870_RS14440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AB870_RS14450	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AB870_RS14455	COG0142	geranyltranstransferase activity
AB870_RS14460	COG1722	exodeoxyribonuclease VII activity
AB870_RS14485	COG0412	Dienelactone hydrolase
AB870_RS14490	COG1252	NADH dehydrogenase
AB870_RS14500	COG1611	Belongs to the LOG family
AB870_RS14505	COG2391	methyltransferase activity
AB870_RS14515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AB870_RS14530	COG0210	DNA helicase
AB870_RS14535	COG0525	valine-tRNA ligase activity
AB870_RS14540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AB870_RS14545	COG0425	Belongs to the sulfur carrier protein TusA family
AB870_RS14565	COG1942	4-Oxalocrotonate Tautomerase
AB870_RS14570	COG0235	Class ii aldolase
AB870_RS14575	COG0477	Major facilitator Superfamily
AB870_RS14580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AB870_RS14585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB870_RS14590	COG1914	H( )-stimulated, divalent metal cation uptake system
AB870_RS14610	COG0517	IMP dehydrogenase activity
AB870_RS14630	COG2801	Transposase and inactivated derivatives
AB870_RS14660	COG2801	Transposase and inactivated derivatives
AB870_RS14675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AB870_RS14685	COG5265	(ABC) transporter
AB870_RS14715	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AB870_RS14720	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS14730	COG0668	transmembrane transport
AB870_RS14760	COG0842	Transport permease protein
AB870_RS14765	COG0842	Transport permease protein
AB870_RS14770	COG1131	(ABC) transporter
AB870_RS14780	COG1309	transcriptional regulator
AB870_RS14790	COG2062	phosphohistidine phosphatase, SixA
AB870_RS14805	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AB870_RS14815	COG0745	RESPONSE REGULATOR receiver
AB870_RS14825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AB870_RS14830	COG0581	inorganic phosphate transmembrane transporter activity
AB870_RS14835	COG0573	inorganic phosphate transmembrane transporter activity
AB870_RS14840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AB870_RS14855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AB870_RS14865	COG1534	Rna-binding protein
AB870_RS14875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AB870_RS14880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AB870_RS14890	COG0505	Belongs to the CarA family
AB870_RS14915	COG1301	dicarboxylic acid transport
AB870_RS14920	COG4266	Belongs to the allantoicase family
AB870_RS14950	COG1960	acyl-CoA dehydrogenase activity
AB870_RS14955	COG1024	Enoyl-CoA hydratase
AB870_RS14960	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS14980	COG0583	DNA-binding transcription factor activity
AB870_RS14985	COG2814	Major facilitator Superfamily
AB870_RS14990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB870_RS14995	COG0741	lytic transglycosylase activity
AB870_RS14995	COG1388	LysM domain
AB870_RS15000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB870_RS15010	COG0328	RNA-DNA hybrid ribonuclease activity
AB870_RS15015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AB870_RS15140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB870_RS15140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB870_RS15150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB870_RS15150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB870_RS15240	COG2271	Major facilitator Superfamily
AB870_RS15255	COG1283	sodium-dependent phosphate transmembrane transporter activity
AB870_RS15275	COG2252	PERMEase
AB870_RS15300	COG0513	Belongs to the DEAD box helicase family
AB870_RS15315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB870_RS15320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB870_RS15350	COG2233	PERMEase
AB870_RS15355	COG0587	DNA-directed DNA polymerase activity
AB870_RS15370	COG1914	H( )-stimulated, divalent metal cation uptake system
AB870_RS15390	COG0789	Transcriptional regulator
AB870_RS15395	COG3568	Endonuclease Exonuclease Phosphatase
AB870_RS15400	COG2217	Heavy metal translocating P-type atpase
AB870_RS15405	COG2608	mercury ion transmembrane transporter activity
AB870_RS15420	COG4651	solute:proton antiporter activity
AB870_RS15420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AB870_RS15440	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AB870_RS15455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AB870_RS15465	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AB870_RS15470	COG2252	PERMEase
AB870_RS15475	COG0402	S-adenosylhomocysteine deaminase activity
AB870_RS15480	COG2119	membrane
AB870_RS15490	COG0308	aminopeptidase N
AB870_RS15505	COG0583	DNA-binding transcription factor activity
AB870_RS15510	COG2814	Major facilitator Superfamily
AB870_RS15525	COG0540	Belongs to the ATCase OTCase family
AB870_RS15575	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AB870_RS15580	COG3842	ATPase activity
AB870_RS15590	COG1175	transmembrane transport
AB870_RS15630	COG1917	Cupin 2, conserved barrel domain protein
AB870_RS15660	COG0411	ABC transporter
AB870_RS15675	COG0583	DNA-binding transcription factor activity
AB870_RS15680	COG1309	transcriptional regulator
AB870_RS15705	COG1012	belongs to the aldehyde dehydrogenase family
AB870_RS15720	COG0583	DNA-binding transcription factor activity
AB870_RS15725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS15740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AB870_RS15755	COG0583	DNA-binding transcription factor activity
AB870_RS15765	COG0693	protein deglycase activity
AB870_RS15785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AB870_RS15805	COG2267	carboxylic ester hydrolase activity
AB870_RS15815	COG1305	Transglutaminase-like
AB870_RS15820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB870_RS15825	COG0583	DNA-binding transcription factor activity
AB870_RS15850	COG1280	lysine exporter protein (LysE YggA)
AB870_RS15865	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AB870_RS15870	COG1845	cytochrome c oxidase, subunit III
AB870_RS15880	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AB870_RS15890	COG1522	sequence-specific DNA binding
AB870_RS15895	COG5001	Diguanylate cyclase
AB870_RS15895	COG3447	MASE1 domain protein
AB870_RS15895	COG5002	protein histidine kinase activity
AB870_RS15900	COG0583	DNA-binding transcription factor activity
AB870_RS15920	COG1742	UPF0060 membrane protein
AB870_RS15925	COG2900	Belongs to the SlyX family
AB870_RS15935	COG1764	response to oxidative stress
AB870_RS15950	COG1522	sequence-specific DNA binding
AB870_RS15960	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS15965	COG0583	DNA-binding transcription factor activity
AB870_RS15980	COG1131	(ABC) transporter
AB870_RS15985	COG0842	Transport permease protein
AB870_RS16000	COG0456	acetyltransferase
AB870_RS16020	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS16040	COG2207	Transcriptional regulator
AB870_RS16065	COG0277	FAD linked oxidase domain protein
AB870_RS16065	COG0247	lactate metabolic process
AB870_RS16075	COG2271	Major facilitator Superfamily
AB870_RS16080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AB870_RS16085	COG1802	Transcriptional regulator
AB870_RS16095	COG1414	Transcriptional regulator
AB870_RS16130	COG1454	alcohol dehydrogenase
AB870_RS16140	COG2197	response regulator
AB870_RS16145	COG3916	Acyl-homoserine-lactone synthase
AB870_RS16205	COG1960	acyl-CoA dehydrogenase activity
AB870_RS16210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB870_RS16220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB870_RS16230	COG1116	anion transmembrane transporter activity
AB870_RS16255	COG0154	amidase activity
AB870_RS16270	COG0583	DNA-binding transcription factor activity
AB870_RS16280	COG1304	FMN binding
AB870_RS16285	COG1522	sequence-specific DNA binding
AB870_RS16290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS16295	COG1113	amino acid transport
AB870_RS16300	COG1309	transcriptional regulator
AB870_RS16330	COG0318	PFAM AMP-dependent synthetase and ligase
AB870_RS16335	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AB870_RS16340	COG2982	Protein involved in outer membrane biogenesis
AB870_RS16345	COG0259	pyridoxamine-phosphate oxidase activity
AB870_RS16350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB870_RS16360	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AB870_RS16365	COG0477	Major facilitator Superfamily
AB870_RS16380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AB870_RS16385	COG0010	Belongs to the arginase family
AB870_RS16390	COG1126	abc transporter atp-binding protein
AB870_RS16395	COG0765	amino acid transport
AB870_RS16400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB870_RS16415	COG1960	acyl-CoA dehydrogenase activity
AB870_RS16425	COG2309	aminopeptidase activity
AB870_RS16430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB870_RS16440	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AB870_RS16450	COG3483	tryptophan 2,3-dioxygenase activity
AB870_RS16460	COG1960	acyl-CoA dehydrogenase activity
AB870_RS16465	COG0450	alkyl hydroperoxide reductase
AB870_RS16470	COG4575	ribosome binding
AB870_RS16485	COG4970	Tfp pilus assembly protein FimT
AB870_RS16515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB870_RS16525	COG1309	transcriptional regulator
AB870_RS16530	COG0725	ABC transporter, periplasmic molybdate-binding protein
AB870_RS16535	COG4149	molybdate abc transporter
AB870_RS16540	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AB870_RS16550	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AB870_RS16555	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AB870_RS16570	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AB870_RS16570	COG3608	succinylglutamate desuccinylase aspartoacylase
AB870_RS16580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB870_RS16610	COG0009	L-threonylcarbamoyladenylate synthase
AB870_RS16615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AB870_RS16620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AB870_RS16625	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AB870_RS16645	COG0469	pyruvate kinase activity
AB870_RS16650	COG0126	phosphoglycerate kinase activity
AB870_RS16680	COG0429	hydrolase of the alpha beta-hydrolase fold
AB870_RS16700	COG0315	cyclic pyranopterin monophosphate synthase activity
AB870_RS16705	COG0697	spore germination
AB870_RS16710	COG1846	Transcriptional regulator
AB870_RS16720	COG0583	DNA-binding transcription factor activity
AB870_RS16725	COG0459	protein refolding
AB870_RS16735	COG0471	metal ion transport
AB870_RS16745	COG5002	protein histidine kinase activity
AB870_RS16750	COG0745	RESPONSE REGULATOR receiver
AB870_RS16755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AB870_RS16760	COG0785	Cytochrome C biogenesis protein
AB870_RS16760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB870_RS16765	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AB870_RS16780	COG2010	Cytochrome c
AB870_RS16810	COG0596	Alpha beta hydrolase
AB870_RS16815	COG1802	Transcriptional regulator
AB870_RS16825	COG3706	GGDEF domain
AB870_RS16850	COG2072	flavoprotein involved in K transport
AB870_RS16855	COG0601	transmembrane transport
AB870_RS16875	COG0747	negative chemotaxis
AB870_RS16930	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AB870_RS16935	COG1988	membrane-bound metal-dependent
AB870_RS16960	COG1335	isochorismatase
AB870_RS16970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB870_RS16990	COG2824	Alkylphosphonate utilization operon protein PhnA
AB870_RS17000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB870_RS17015	COG0243	molybdopterin cofactor binding
AB870_RS17025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB870_RS17030	COG1960	acyl-CoA dehydrogenase activity
AB870_RS17050	COG1566	PFAM secretion protein HlyD family protein
AB870_RS17065	COG2197	response regulator
AB870_RS17070	COG0583	DNA-binding transcription factor activity
AB870_RS17075	COG0583	DNA-binding transcription factor activity
AB870_RS17090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB870_RS17120	COG2099	Precorrin-6x reductase
AB870_RS17185	COG0778	Nitroreductase
AB870_RS17190	COG2271	Major facilitator Superfamily
AB870_RS17205	COG1595	DNA-templated transcription, initiation
AB870_RS17215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AB870_RS17225	COG0436	Aminotransferase
AB870_RS17245	COG0183	Belongs to the thiolase family
AB870_RS17250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AB870_RS17265	COG0583	DNA-binding transcription factor activity
AB870_RS17270	COG3284	Transcriptional regulator
AB870_RS17275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS17280	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AB870_RS17300	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS17305	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AB870_RS17315	COG0433	COG0433 Predicted ATPase
AB870_RS17320	COG0217	transcriptional regulatory protein
AB870_RS17325	COG0151	Belongs to the GarS family
AB870_RS17330	COG0668	transmembrane transport
AB870_RS17335	COG0408	coproporphyrinogen oxidase activity
AB870_RS17345	COG0799	negative regulation of ribosome biogenesis
AB870_RS17355	COG1653	transport
AB870_RS17360	COG1175	transmembrane transport
AB870_RS17365	COG0395	ABC-type sugar transport system, permease component
AB870_RS17375	COG0584	glycerophosphoryl diester phosphodiesterase
AB870_RS17380	COG0424	maF-like protein
AB870_RS17385	COG1530	ribonuclease E activity
AB870_RS17420	COG0514	ATP-dependent DNA helicase (RecQ)
AB870_RS17450	COG1054	Belongs to the UPF0176 family
AB870_RS17455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB870_RS17460	COG0513	Belongs to the DEAD box helicase family
AB870_RS17470	COG0583	DNA-binding transcription factor activity
AB870_RS17495	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AB870_RS17505	COG1253	flavin adenine dinucleotide binding
AB870_RS17510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AB870_RS17515	COG1074	ATP-dependent DNA helicase activity
AB870_RS17520	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AB870_RS17525	COG1289	transmembrane transporter activity
AB870_RS17530	COG2197	response regulator
AB870_RS17540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB870_RS17545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB870_RS17550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB870_RS17570	COG2916	Histone family protein nucleoid-structuring protein H-NS
AB870_RS17580	COG0477	Major facilitator Superfamily
AB870_RS17595	COG0640	Transcriptional regulator
AB870_RS17605	COG0583	DNA-binding transcription factor activity
AB870_RS17620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB870_RS17625	COG0765	amino acid transport
AB870_RS17630	COG0765	amino acid transport
AB870_RS17650	COG2207	Transcriptional regulator
AB870_RS17650	COG1917	Cupin 2, conserved barrel domain protein
AB870_RS17655	COG0346	lactoylglutathione lyase activity
AB870_RS17690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB870_RS17710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AB870_RS17710	COG0543	2 iron, 2 sulfur cluster binding
AB870_RS17715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AB870_RS17735	COG0411	ABC transporter
AB870_RS17755	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AB870_RS17760	COG1047	Peptidyl-prolyl cis-trans
AB870_RS17765	COG2003	Belongs to the UPF0758 family
AB870_RS17770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AB870_RS17775	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AB870_RS17780	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AB870_RS17790	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AB870_RS17800	COG3264	Mechanosensitive ion channel
AB870_RS17800	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AB870_RS17805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AB870_RS17805	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AB870_RS17810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AB870_RS17815	COG0196	riboflavin kinase activity
AB870_RS17820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AB870_RS17825	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AB870_RS17830	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AB870_RS17835	COG2814	Major facilitator Superfamily
AB870_RS17840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB870_RS17850	COG0542	response to heat
AB870_RS17855	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AB870_RS17860	COG1278	Cold shock
AB870_RS17890	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS17895	COG0583	DNA-binding transcription factor activity
AB870_RS17935	COG3437	response regulator, receiver
AB870_RS17935	COG0784	Response regulator, receiver
AB870_RS17940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AB870_RS17945	COG1570	exodeoxyribonuclease VII activity
AB870_RS17950	COG0811	peptide transport
AB870_RS17960	COG1663	tetraacyldisaccharide 4'-kinase activity
AB870_RS17965	COG2835	tetraacyldisaccharide 4'-kinase activity
AB870_RS17975	COG0563	adenylate kinase activity
AB870_RS17990	COG2912	Transglutaminase-like superfamily
AB870_RS17995	COG0728	peptidoglycan biosynthetic process
AB870_RS18000	COG0268	Binds directly to 16S ribosomal RNA
AB870_RS18010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AB870_RS18015	COG3123	guanosine phosphorylase activity
AB870_RS18030	COG1666	GTP binding
AB870_RS18035	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AB870_RS18040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AB870_RS18045	COG0318	PFAM AMP-dependent synthetase and ligase
AB870_RS18050	COG4974	Belongs to the 'phage' integrase family
AB870_RS18055	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AB870_RS18060	COG0802	atpase or kinase
AB870_RS18070	COG0586	Pfam SNARE associated Golgi protein
AB870_RS18080	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AB870_RS18095	COG3842	ATPase activity
AB870_RS18105	COG1176	ABC-type spermidine putrescine transport system, permease component I
AB870_RS18115	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AB870_RS18130	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AB870_RS18140	COG0617	tRNA 3'-terminal CCA addition
AB870_RS18145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AB870_RS18150	COG1428	Deoxynucleoside kinase
AB870_RS18155	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AB870_RS18160	COG2205	protein histidine kinase activity
AB870_RS18175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB870_RS18190	COG0484	heat shock protein binding
AB870_RS18205	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AB870_RS18220	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AB870_RS18245	COG0497	DNA recombination
AB870_RS18250	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AB870_RS18260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AB870_RS18265	COG0312	modulator of DNA gyrase
AB870_RS18270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AB870_RS18275	COG2096	Adenosyltransferase
AB870_RS18280	COG0277	FAD linked oxidase domain protein
AB870_RS18285	COG0277	FAD linked oxidase domain protein
AB870_RS18290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB870_RS18295	COG0277	FAD linked oxidase domain protein
AB870_RS18300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB870_RS18310	COG0386	Belongs to the glutathione peroxidase family
AB870_RS18325	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AB870_RS18335	COG0672	)-iron permease
AB870_RS18340	COG4633	Protein conserved in bacteria
AB870_RS18355	COG0765	amino acid transport
AB870_RS18360	COG0765	amino acid transport
AB870_RS18430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AB870_RS18435	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AB870_RS18475	COG2721	sulfolactate sulfo-lyase activity
AB870_RS18480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB870_RS18515	COG3842	ATPase activity
AB870_RS18525	COG4948	Mandelate Racemase Muconate Lactonizing
AB870_RS18530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS18535	COG2188	Transcriptional regulator
AB870_RS18555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AB870_RS18560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AB870_RS18585	COG0736	holo-[acyl-carrier-protein] synthase activity
AB870_RS18600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AB870_RS18605	COG0571	ribonuclease III activity
AB870_RS18610	COG0681	Belongs to the peptidase S26 family
AB870_RS18625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB870_RS18645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AB870_RS18650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AB870_RS18655	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS18670	COG0416	fatty acid biosynthetic process
AB870_RS18675	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AB870_RS18680	COG1399	metal-binding, possibly nucleic acid-binding protein
AB870_RS18690	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AB870_RS18695	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AB870_RS18695	COG0616	signal peptide processing
AB870_RS18705	COG0546	phosphoglycolate phosphatase activity
AB870_RS18710	COG0564	pseudouridine synthase activity
AB870_RS18715	COG1530	ribonuclease E activity
AB870_RS18720	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AB870_RS18730	COG0746	molybdenum cofactor guanylyltransferase activity
AB870_RS18735	COG0303	'Molybdopterin
AB870_RS18765	COG1556	Lactate utilization protein
AB870_RS18770	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AB870_RS18775	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AB870_RS18800	COG0277	FAD linked oxidase domain protein
AB870_RS18805	COG0277	FAD linked oxidase domain protein
AB870_RS18810	COG0247	lactate metabolic process
AB870_RS18820	COG3384	dioxygenase
AB870_RS18825	COG0583	DNA-binding transcription factor activity
AB870_RS18830	COG1253	flavin adenine dinucleotide binding
AB870_RS18840	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AB870_RS18850	COG1278	Cold shock
AB870_RS18855	COG4942	peptidase
AB870_RS18860	COG2943	transferase activity, transferring hexosyl groups
AB870_RS18860	COG3416	Protein conserved in bacteria
AB870_RS18865	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AB870_RS18880	COG0534	Mate efflux family protein
AB870_RS18895	COG2807	transmembrane transport
AB870_RS18905	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AB870_RS18915	COG1802	Transcriptional regulator
AB870_RS18920	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AB870_RS18930	COG2198	Histidine kinase
AB870_RS18930	COG2205	protein histidine kinase activity
AB870_RS18930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB870_RS18930	COG0784	Response regulator, receiver
AB870_RS18945	COG0583	DNA-binding transcription factor activity
AB870_RS18970	COG2855	membrane
AB870_RS18985	COG2885	chlorophyll binding
AB870_RS19015	COG0531	amino acid
AB870_RS19060	COG3781	membrane
AB870_RS19085	COG0583	DNA-binding transcription factor activity
AB870_RS19090	COG2814	Major facilitator Superfamily
AB870_RS19095	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AB870_RS19110	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AB870_RS19125	COG0625	glutathione transferase activity
AB870_RS19135	COG3468	outer membrane autotransporter barrel domain protein
AB870_RS19155	COG2814	Major facilitator Superfamily
AB870_RS19180	COG2814	Major facilitator Superfamily
AB870_RS19190	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AB870_RS19195	COG1968	undecaprenyl-diphosphatase activity
AB870_RS19220	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AB870_RS19260	COG0438	transferase activity, transferring glycosyl groups
AB870_RS19265	COG0438	transferase activity, transferring glycosyl groups
AB870_RS19270	COG0438	transferase activity, transferring glycosyl groups
AB870_RS19275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AB870_RS19280	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AB870_RS19300	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AB870_RS19305	COG1678	Uncharacterized ACR, COG1678
AB870_RS19315	COG1773	rubredoxin
AB870_RS19330	COG4969	Belongs to the N-Me-Phe pilin family
AB870_RS19335	COG0861	Integral membrane protein TerC family
AB870_RS19340	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AB870_RS19345	COG0045	succinate-CoA ligase (ADP-forming) activity
AB870_RS19355	COG2137	regulation of response to DNA damage stimulus
AB870_RS19360	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AB870_RS19370	COG0642	Histidine kinase
AB870_RS19390	COG1253	flavin adenine dinucleotide binding
AB870_RS19395	COG0583	DNA-binding transcription factor activity
AB870_RS19400	COG0628	permease
AB870_RS19415	COG1116	anion transmembrane transporter activity
AB870_RS19425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB870_RS19430	COG0156	8-amino-7-oxononanoate synthase activity
AB870_RS19435	COG1396	sequence-specific DNA binding
AB870_RS19440	COG0840	transmembrane signaling receptor activity
AB870_RS19455	COG1902	pentaerythritol trinitrate reductase activity
AB870_RS19460	COG0668	transmembrane transport
AB870_RS19485	COG3706	GGDEF domain
AB870_RS19495	COG2719	SpoVR family
AB870_RS19500	COG2718	Belongs to the UPF0229 family
AB870_RS19505	COG2766	serine protein kinase
AB870_RS19525	COG1121	(ABC) transporter
AB870_RS19535	COG0803	Belongs to the bacterial solute-binding protein 9 family
AB870_RS19540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AB870_RS19545	COG1702	phosphate starvation-inducible protein PhoH
AB870_RS19550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AB870_RS19555	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AB870_RS19565	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AB870_RS19570	COG0752	glycyl-tRNA synthetase alpha subunit
AB870_RS19575	COG0751	glycine-tRNA ligase activity
AB870_RS19580	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AB870_RS19585	COG0204	Acyl-transferase
AB870_RS19595	COG0346	lactoylglutathione lyase activity
AB870_RS19600	COG1773	rubredoxin
AB870_RS19610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AB870_RS19615	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AB870_RS19620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB870_RS19625	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AB870_RS19630	COG3178	'Phosphotransferase
AB870_RS19635	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AB870_RS19640	COG0006	proline dipeptidase activity
AB870_RS19645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB870_RS19655	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AB870_RS19660	COG0138	bifunctional purine biosynthesis protein purh
AB870_RS19665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS19670	COG3608	succinylglutamate desuccinylase aspartoacylase
AB870_RS19670	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AB870_RS19695	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AB870_RS19710	COG0495	leucyl-tRNA aminoacylation
AB870_RS19715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AB870_RS19720	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AB870_RS19725	COG0735	belongs to the Fur family
AB870_RS19740	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AB870_RS19745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AB870_RS19750	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AB870_RS19760	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AB870_RS19775	COG4290	ribonuclease
AB870_RS19780	COG0280	phosphate acetyltransferase
AB870_RS19780	COG0281	malic enzyme
AB870_RS19790	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AB870_RS19795	COG1546	Belongs to the CinA family
AB870_RS19800	COG0284	orotidine-5'-phosphate decarboxylase activity
AB870_RS19810	COG0668	transmembrane transport
AB870_RS19815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB870_RS19820	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AB870_RS19835	COG0557	exoribonuclease II activity
AB870_RS19840	COG3150	esterase
AB870_RS19845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AB870_RS19855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB870_RS19860	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AB870_RS19865	COG0511	ligase activity, forming carbon-carbon bonds
AB870_RS19870	COG0439	Biotin carboxylase
AB870_RS19875	COG2264	protein methyltransferase activity
AB870_RS19890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AB870_RS19895	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AB870_RS19895	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AB870_RS19910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB870_RS19940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AB870_RS19945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AB870_RS19950	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AB870_RS19960	COG2095	MarC family integral membrane protein
AB870_RS19965	COG0442	prolyl-tRNA aminoacylation
AB870_RS19990	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AB870_RS19995	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AB870_RS20000	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AB870_RS20005	COG0142	geranyltranstransferase activity
AB870_RS20015	COG4536	flavin adenine dinucleotide binding
AB870_RS20040	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AB870_RS20045	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AB870_RS20055	COG0494	nUDIX hydrolase
AB870_RS20065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AB870_RS20070	COG0653	protein targeting
AB870_RS20080	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AB870_RS20095	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AB870_RS20100	COG1181	Belongs to the D-alanine--D-alanine ligase family
AB870_RS20105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AB870_RS20110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AB870_RS20120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AB870_RS20130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AB870_RS20135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AB870_RS20145	COG3116	cell division
AB870_RS20150	COG0275	rRNA processing
AB870_RS20165	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AB870_RS20180	COG0243	molybdopterin cofactor binding
AB870_RS20185	COG1473	amidohydrolase
AB870_RS20225	COG1024	Enoyl-CoA hydratase
AB870_RS20235	COG0183	Belongs to the thiolase family
AB870_RS20240	COG1024	Enoyl-CoA hydratase
AB870_RS20245	COG2050	protein possibly involved in aromatic compounds catabolism
AB870_RS20260	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AB870_RS20270	COG2967	ApaG domain
AB870_RS20275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AB870_RS20280	COG0546	phosphoglycolate phosphatase activity
AB870_RS20295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB870_RS20300	COG1129	ABC transporter
AB870_RS20300	COG0842	Transport permease protein
AB870_RS20305	COG0842	Transport permease protein
AB870_RS20315	COG0642	Histidine kinase
AB870_RS20325	COG4232	protein-disulfide reductase activity
AB870_RS20330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB870_RS20345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AB870_RS20350	COG0134	indole-3-glycerol-phosphate synthase activity
AB870_RS20360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AB870_RS20365	COG4774	siderophore transport
AB870_RS20390	COG0583	DNA-binding transcription factor activity
AB870_RS20405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB870_RS20410	COG2321	neutral zinc metallopeptidase
AB870_RS20415	COG0012	GTP binding
AB870_RS20435	COG0463	Glycosyl transferase, family 2
AB870_RS20450	COG0477	Major facilitator Superfamily
AB870_RS20455	COG2261	transglycosylase associated protein
AB870_RS20460	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AB870_RS20465	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AB870_RS20470	COG2890	protein-(glutamine-N5) methyltransferase activity
AB870_RS20475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AB870_RS20505	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AB870_RS20510	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AB870_RS20515	COG0835	chemotaxis
AB870_RS20525	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS20530	COG0488	(ABC) transporter
AB870_RS20545	COG1408	metallophosphoesterase
AB870_RS20550	COG1254	Belongs to the acylphosphatase family
AB870_RS20560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AB870_RS20570	COG2271	Major facilitator Superfamily
AB870_RS20590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AB870_RS20595	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AB870_RS20660	COG3045	CreA protein
AB870_RS20665	COG3284	Transcriptional regulator
AB870_RS20675	COG1454	alcohol dehydrogenase
AB870_RS20680	COG2271	Major facilitator Superfamily
AB870_RS20695	COG1737	Transcriptional regulator
AB870_RS20705	COG1473	amidohydrolase
AB870_RS20755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB870_RS20765	COG3210	domain, Protein
AB870_RS20770	COG1414	Transcriptional regulator
AB870_RS20775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB870_RS20780	COG3384	dioxygenase
AB870_RS20785	COG3971	2-oxopent-4-enoate hydratase activity
AB870_RS20790	COG2814	Major facilitator Superfamily
AB870_RS20795	COG2267	carboxylic ester hydrolase activity
AB870_RS20840	COG2801	Transposase and inactivated derivatives
AB870_RS20910	COG2969	positive regulation of protein catabolic process
AB870_RS20915	COG0625	glutathione transferase activity
AB870_RS20920	COG2857	Cytochrome c1
AB870_RS20925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AB870_RS20930	COG0723	plastoquinol--plastocyanin reductase activity
AB870_RS20940	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AB870_RS20945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB870_RS20950	COG0805	protein transport
AB870_RS20960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AB870_RS20980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AB870_RS20985	COG0107	imidazoleglycerol-phosphate synthase activity
AB870_RS20990	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AB870_RS20995	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AB870_RS21000	COG2095	MarC family integral membrane protein
AB870_RS21020	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AB870_RS21030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AB870_RS21040	COG0842	Transport permease protein
AB870_RS21045	COG1131	(ABC) transporter
AB870_RS21065	COG2853	Lipoprotein
AB870_RS21070	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB870_RS21075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB870_RS21080	COG1127	ABC transporter
AB870_RS21100	COG2104	thiamine diphosphate biosynthetic process
AB870_RS21110	COG4178	(ABC) transporter
AB870_RS21115	COG1028	Short-chain dehydrogenase reductase Sdr
AB870_RS21120	COG2814	Major facilitator Superfamily
AB870_RS21130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB870_RS21135	COG2271	Major facilitator Superfamily
AB870_RS21145	COG0070	glutamate synthase
AB870_RS21145	COG0069	glutamate synthase activity
AB870_RS21145	COG0067	glutamate synthase
AB870_RS21155	COG3047	cAMP biosynthetic process
AB870_RS21180	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AB870_RS21215	COG1965	Belongs to the frataxin family
AB870_RS21220	COG0019	diaminopimelate decarboxylase activity
AB870_RS21225	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AB870_RS21230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AB870_RS21235	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AB870_RS21240	COG1333	cytochrome c biogenesis protein
AB870_RS21250	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AB870_RS21260	COG4232	protein-disulfide reductase activity
AB870_RS21270	COG0203	ribosomal protein L17
AB870_RS21275	COG0202	RNA polymerase activity
AB870_RS21280	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AB870_RS21285	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AB870_RS21290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AB870_RS21295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AB870_RS21300	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AB870_RS21305	COG0201	protein transport
AB870_RS21310	COG0200	Binds to the 23S rRNA
AB870_RS21325	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AB870_RS21330	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AB870_RS21340	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AB870_RS21345	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AB870_RS21350	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AB870_RS21355	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AB870_RS21365	COG0255	Belongs to the universal ribosomal protein uL29 family
AB870_RS21375	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AB870_RS21380	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AB870_RS21385	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AB870_RS21390	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AB870_RS21395	COG0089	rRNA binding
AB870_RS21400	COG0088	Forms part of the polypeptide exit tunnel
AB870_RS21405	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AB870_RS21410	COG0051	transcription antitermination factor activity, RNA binding
AB870_RS21425	COG0049	tRNA binding
AB870_RS21430	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AB870_RS21435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB870_RS21450	COG2207	Transcriptional regulator
AB870_RS21475	COG0583	DNA-binding transcription factor activity
AB870_RS21480	COG1448	Aminotransferase
AB870_RS21490	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AB870_RS21515	COG3971	2-oxopent-4-enoate hydratase activity
AB870_RS21525	COG4772	TonB-dependent receptor
AB870_RS21550	COG0222	ribosome binding
AB870_RS21555	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AB870_RS21565	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AB870_RS21585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AB870_RS21630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB870_RS21645	COG3396	Phenylacetate-CoA oxygenase
AB870_RS21650	COG3460	Phenylacetate-CoA oxygenase
AB870_RS21655	COG3396	Phenylacetate-CoA oxygenase
AB870_RS21660	COG2151	metal-sulfur cluster biosynthetic enzyme
AB870_RS21665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AB870_RS21705	COG2814	Major facilitator Superfamily
AB870_RS21710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AB870_RS21725	COG2226	methyltransferase
AB870_RS21745	COG0513	Belongs to the DEAD box helicase family
AB870_RS21750	COG0583	DNA-binding transcription factor activity
AB870_RS21755	COG2233	PERMEase
AB870_RS21765	COG0392	lysyltransferase activity
AB870_RS21770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AB870_RS21775	COG2827	Endonuclease containing a URI domain
AB870_RS21825	COG2814	Major facilitator Superfamily
AB870_RS21830	COG4336	lyase activity
AB870_RS21835	COG0583	DNA-binding transcription factor activity
AB870_RS21845	COG1845	cytochrome c oxidase, subunit III
AB870_RS21850	COG1845	cytochrome c oxidase, subunit III
AB870_RS21855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AB870_RS21860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AB870_RS21875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB870_RS21905	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AB870_RS21920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AB870_RS21925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AB870_RS21980	COG3846	protein secretion by the type IV secretion system
AB870_RS22025	COG0737	Belongs to the 5'-nucleotidase family
AB870_RS22035	COG2010	Cytochrome c
AB870_RS22055	COG4654	Cytochrome c, class I
AB870_RS22060	COG4654	Cytochrome c, class I
AB870_RS22065	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AB870_RS22080	COG0446	pyridine nucleotide-disulphide oxidoreductase
AB870_RS22090	COG2823	Periplasmic or secreted lipoprotein
AB870_RS22095	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AB870_RS22100	COG0792	nuclease activity
AB870_RS22115	COG1122	ATPase activity
AB870_RS22135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB870_RS22155	COG3622	Belongs to the hyi family
AB870_RS22160	COG1832	CoA-binding protein
AB870_RS22165	COG0657	acetylesterase activity
AB870_RS22175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AB870_RS22180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AB870_RS22195	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AB870_RS22195	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AB870_RS22195	COG0506	proline dehydrogenase activity
AB870_RS22210	COG1115	amino acid carrier protein
AB870_RS22220	COG1760	l-serine dehydratase
AB870_RS22225	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AB870_RS22225	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AB870_RS22230	COG0509	glycine decarboxylation via glycine cleavage system
AB870_RS22235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AB870_RS22250	COG0210	DNA helicase
AB870_RS22260	COG3245	cytochrome
AB870_RS22300	COG2205	protein histidine kinase activity
AB870_RS22305	COG0745	RESPONSE REGULATOR receiver
AB870_RS22320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB870_RS22330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB870_RS22335	COG0745	RESPONSE REGULATOR receiver
AB870_RS22345	COG3851	Histidine kinase
AB870_RS22350	COG2197	response regulator
AB870_RS22360	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AB870_RS22380	COG2257	FlhB HrpN YscU SpaS Family
AB870_RS22385	COG1677	Flagellar hook-basal body complex protein FliE
AB870_RS22420	COG1580	Controls the rotational direction of flagella during chemotaxis
AB870_RS22430	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AB870_RS22440	COG1338	Plays a role in the flagellum-specific transport system
AB870_RS22460	COG1256	bacterial-type flagellum assembly
AB870_RS22470	COG1706	bacterial-type flagellum-dependent cell motility
AB870_RS22475	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AB870_RS22485	COG4787	bacterial-type flagellum-dependent cell motility
AB870_RS22500	COG1558	bacterial-type flagellum-dependent cell motility
AB870_RS22505	COG1815	bacterial-type flagellum-dependent cell motility
AB870_RS22525	COG1191	sigma factor activity
AB870_RS22540	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AB870_RS22550	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AB870_RS22555	COG0745	RESPONSE REGULATOR receiver
AB870_RS22565	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AB870_RS22570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AB870_RS22575	COG0840	transmembrane signaling receptor activity
AB870_RS22580	COG0840	transmembrane signaling receptor activity
AB870_RS22585	COG0840	transmembrane signaling receptor activity
AB870_RS22590	COG0835	chemotaxis
AB870_RS22595	COG2198	Histidine kinase
AB870_RS22595	COG0643	Histidine kinase
AB870_RS22600	COG2205	protein histidine kinase activity
AB870_RS22600	COG0784	Response regulator, receiver
AB870_RS22600	COG2198	Histidine kinase
AB870_RS22605	COG1360	Flagellar Motor Protein
AB870_RS22625	COG2814	Major facilitator Superfamily
AB870_RS22630	COG0318	PFAM AMP-dependent synthetase and ligase
AB870_RS22640	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AB870_RS22645	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AB870_RS22650	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AB870_RS22665	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AB870_RS22675	COG0356	it plays a direct role in the translocation of protons across the membrane
AB870_RS22685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AB870_RS22690	COG1475	DNA binding
AB870_RS22695	COG1192	Involved in chromosome partitioning
AB870_RS22700	COG3040	lipid binding
AB870_RS22705	COG0357	Ribosomal RNA small subunit methyltransferase G
AB870_RS22710	COG0445	tRNA wobble uridine modification
AB870_RS22740	COG1846	Transcriptional regulator
AB870_RS22765	COG0559	Belongs to the binding-protein-dependent transport system permease family
AB870_RS22805	COG4106	trans-aconitate 2-methyltransferase activity
AB870_RS22815	COG0583	DNA-binding transcription factor activity
AB870_RS22820	COG0114	fumarate hydratase activity
AB870_RS22835	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AB870_RS22865	COG1522	sequence-specific DNA binding
AB870_RS22875	COG4771	TonB-dependent receptor
AB870_RS22880	COG3720	iron ion transport
AB870_RS22885	COG4558	Periplasmic binding protein
AB870_RS22890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB870_RS22900	COG2423	ornithine cyclodeaminase activity
AB870_RS22905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB870_RS22925	COG1522	sequence-specific DNA binding
AB870_RS22930	COG3186	Phenylalanine-4-hydroxylase
AB870_RS22935	COG2154	pterin-4-alpha-carbinolamine dehydratase
AB870_RS22950	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AB870_RS22960	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AB870_RS22960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB870_RS22965	COG0038	chloride channel
AB870_RS22970	COG1846	Transcriptional regulator
AB870_RS22980	COG2814	Major facilitator Superfamily
AB870_RS22985	COG3300	MHYT domain
AB870_RS22985	COG5001	Diguanylate cyclase
AB870_RS23025	COG0706	membrane insertase activity
AB870_RS23030	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AB870_RS23035	COG0594	ribonuclease P activity
AB870_RS23040	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AB870_RS23070	COG0187	DNA topoisomerase II activity
AB870_RS23235	COG4774	siderophore transport
AB870_RS23955	COG0768	penicillin binding
AB870_RS24560	COG0436	Aminotransferase
AB870_RS24725	COG0137	argininosuccinate synthase activity
AB870_RS24840	COG1741	Belongs to the pirin family
AB870_RS25420	COG0643	Histidine kinase
AB870_RS25420	COG2198	Histidine kinase