locus-tag	class	description
FKQ53_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FKQ53_RS00025	COG3328	transposase activity
FKQ53_RS00045	COG0583	DNA-binding transcription factor activity
FKQ53_RS00055	COG0402	S-adenosylhomocysteine deaminase activity
FKQ53_RS00060	COG0583	DNA-binding transcription factor activity
FKQ53_RS00065	COG1017	nitric oxide dioxygenase activity
FKQ53_RS00065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FKQ53_RS00070	COG2423	ornithine cyclodeaminase activity
FKQ53_RS00075	COG2031	fatty acid transporter
FKQ53_RS00080	COG0833	amino acid
FKQ53_RS00110	COG0840	transmembrane signaling receptor activity
FKQ53_RS00125	COG1136	(ABC) transporter
FKQ53_RS00140	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FKQ53_RS00150	COG0583	DNA-binding transcription factor activity
FKQ53_RS00155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKQ53_RS00160	COG0765	amino acid transport
FKQ53_RS00165	COG0765	amino acid transport
FKQ53_RS00200	COG1252	NADH dehydrogenase
FKQ53_RS00205	COG1309	transcriptional regulator
FKQ53_RS00220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FKQ53_RS00240	COG1968	undecaprenyl-diphosphatase activity
FKQ53_RS00245	COG0583	DNA-binding transcription factor activity
FKQ53_RS00270	COG2733	membrane
FKQ53_RS00280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FKQ53_RS00285	COG3340	Belongs to the peptidase S51 family
FKQ53_RS00305	COG0583	DNA-binding transcription factor activity
FKQ53_RS00315	COG0583	DNA-binding transcription factor activity
FKQ53_RS00320	COG2814	Major facilitator Superfamily
FKQ53_RS00335	COG2200	EAL domain
FKQ53_RS00340	COG2223	nitrite transmembrane transporter activity
FKQ53_RS00350	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FKQ53_RS00365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FKQ53_RS00375	COG0840	transmembrane signaling receptor activity
FKQ53_RS00385	COG0457	Tetratricopeptide repeat
FKQ53_RS00385	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FKQ53_RS00390	COG0835	chemotaxis
FKQ53_RS00400	COG2201	protein-glutamate methylesterase activity
FKQ53_RS00405	COG4251	negative regulation of phosphorylation
FKQ53_RS00405	COG3706	GGDEF domain
FKQ53_RS00405	COG2203	Gaf domain
FKQ53_RS00405	COG5001	Diguanylate cyclase
FKQ53_RS00430	COG1473	amidohydrolase
FKQ53_RS00440	COG0183	Belongs to the thiolase family
FKQ53_RS00480	COG1802	Transcriptional regulator
FKQ53_RS00495	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FKQ53_RS00495	COG1672	PFAM Archaeal ATPase
FKQ53_RS00500	COG4774	siderophore transport
FKQ53_RS00505	COG3128	pkhd-type hydroxylase
FKQ53_RS00540	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FKQ53_RS00555	COG1966	Carbon starvation protein
FKQ53_RS00560	COG2879	small protein
FKQ53_RS00570	COG0583	DNA-binding transcription factor activity
FKQ53_RS00585	COG0758	DNA mediated transformation
FKQ53_RS00585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FKQ53_RS00590	COG0242	peptide deformylase activity
FKQ53_RS00600	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FKQ53_RS00605	COG0501	Belongs to the peptidase M48B family
FKQ53_RS00610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FKQ53_RS00610	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FKQ53_RS00620	COG5000	phosphorelay sensor kinase activity
FKQ53_RS00625	COG2204	response regulator
FKQ53_RS00625	COG2204	response regulator
FKQ53_RS00640	COG0602	queuosine metabolic process
FKQ53_RS00645	COG0720	synthase
FKQ53_RS00695	COG2207	Transcriptional regulator
FKQ53_RS00730	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FKQ53_RS00815	COG0772	Belongs to the SEDS family
FKQ53_RS00820	COG0768	penicillin binding
FKQ53_RS00830	COG1792	Involved in formation and maintenance of cell shape
FKQ53_RS00835	COG1077	Cell shape determining protein MreB Mrl
FKQ53_RS00840	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FKQ53_RS00855	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FKQ53_RS00860	COG2326	polyphosphate kinase activity
FKQ53_RS00910	COG1960	acyl-CoA dehydrogenase activity
FKQ53_RS00925	COG1560	Kdo2-lipid A biosynthetic process
FKQ53_RS00930	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FKQ53_RS00940	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FKQ53_RS00945	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FKQ53_RS00960	COG0523	cobalamin synthesis protein
FKQ53_RS00975	COG4206	TonB-dependent receptor
FKQ53_RS00980	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FKQ53_RS00985	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FKQ53_RS00990	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FKQ53_RS00995	COG0642	Histidine kinase
FKQ53_RS01005	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FKQ53_RS01030	COG0477	Major facilitator Superfamily
FKQ53_RS01045	COG2188	Transcriptional regulator
FKQ53_RS01055	COG3384	dioxygenase
FKQ53_RS01065	COG0683	leucine binding
FKQ53_RS01090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FKQ53_RS01095	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FKQ53_RS01100	COG2828	Protein conserved in bacteria
FKQ53_RS01115	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS01120	COG2814	Major facilitator Superfamily
FKQ53_RS01130	COG1309	transcriptional regulator
FKQ53_RS01135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FKQ53_RS01140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FKQ53_RS01140	COG2813	Specifically methylates the guanine in position
FKQ53_RS01145	COG2814	Major facilitator Superfamily
FKQ53_RS01155	COG0708	Exodeoxyribonuclease III
FKQ53_RS01160	COG0583	DNA-binding transcription factor activity
FKQ53_RS01165	COG1380	Effector of murein hydrolase LrgA
FKQ53_RS01170	COG1346	cytolysis
FKQ53_RS01175	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FKQ53_RS01180	COG1950	PFAM Membrane protein of
FKQ53_RS01185	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FKQ53_RS01190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FKQ53_RS01195	COG0747	negative chemotaxis
FKQ53_RS01200	COG0601	transmembrane transport
FKQ53_RS01205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FKQ53_RS01210	COG0444	Belongs to the ABC transporter superfamily
FKQ53_RS01215	COG4608	Belongs to the ABC transporter superfamily
FKQ53_RS01225	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FKQ53_RS01230	COG0830	nickel cation binding
FKQ53_RS01240	COG0804	urea catabolic process
FKQ53_RS01245	COG0832	Belongs to the urease beta subunit family
FKQ53_RS01255	COG0831	urea catabolic process
FKQ53_RS01260	COG1126	abc transporter atp-binding protein
FKQ53_RS01265	COG0765	amino acid transport
FKQ53_RS01270	COG0765	amino acid transport
FKQ53_RS01275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKQ53_RS01310	COG2814	Major facilitator Superfamily
FKQ53_RS01320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKQ53_RS01325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FKQ53_RS01335	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FKQ53_RS01340	COG1984	allophanate hydrolase subunit 2
FKQ53_RS01345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FKQ53_RS01365	COG0625	glutathione transferase activity
FKQ53_RS01370	COG0617	tRNA 3'-terminal CCA addition
FKQ53_RS01390	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS01400	COG0037	tRNA processing
FKQ53_RS01405	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FKQ53_RS01410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FKQ53_RS01430	COG1450	Type ii and iii secretion system protein
FKQ53_RS01480	COG1104	cysteine desulfurase activity
FKQ53_RS01500	COG0038	chloride channel
FKQ53_RS01550	COG0583	DNA-binding transcription factor activity
FKQ53_RS01565	COG0625	glutathione transferase activity
FKQ53_RS01570	COG0583	DNA-binding transcription factor activity
FKQ53_RS01600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKQ53_RS01610	COG3511	phospholipase C
FKQ53_RS01640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FKQ53_RS01640	COG2169	Transcriptional regulator
FKQ53_RS01660	COG1741	Belongs to the pirin family
FKQ53_RS01670	COG1739	Uncharacterized protein family UPF0029
FKQ53_RS01680	COG2132	Multicopper oxidase
FKQ53_RS01680	COG2132	Multicopper oxidase
FKQ53_RS01725	COG1250	3-hydroxyacyl-CoA dehydrogenase
FKQ53_RS01780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FKQ53_RS01785	COG4681	YaeQ
FKQ53_RS01805	COG0697	spore germination
FKQ53_RS01815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS01820	COG2084	Dehydrogenase
FKQ53_RS01830	COG4770	biotin carboxylase activity
FKQ53_RS01835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FKQ53_RS01840	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FKQ53_RS01845	COG0156	8-amino-7-oxononanoate synthase activity
FKQ53_RS01860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FKQ53_RS01865	COG3012	SEC-C Motif Domain Protein
FKQ53_RS01875	COG0300	oxidoreductase activity
FKQ53_RS01880	COG0183	Belongs to the thiolase family
FKQ53_RS01885	COG0288	reversible hydration of carbon dioxide
FKQ53_RS01890	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FKQ53_RS01895	COG1960	acyl-CoA dehydrogenase activity
FKQ53_RS01905	COG0789	Transcriptional regulator
FKQ53_RS01930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FKQ53_RS01940	COG0018	arginyl-trna synthetase
FKQ53_RS01955	COG1285	pathogenesis
FKQ53_RS01980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FKQ53_RS02045	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FKQ53_RS02070	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FKQ53_RS02075	COG1127	ABC transporter
FKQ53_RS02095	COG2814	Major facilitator Superfamily
FKQ53_RS02110	COG1686	Belongs to the peptidase S11 family
FKQ53_RS02115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FKQ53_RS02120	COG2921	Belongs to the UPF0250 family
FKQ53_RS02125	COG0583	DNA-binding transcription factor activity
FKQ53_RS02140	COG0321	lipoyl(octanoyl) transferase activity
FKQ53_RS02170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKQ53_RS02180	COG1301	dicarboxylic acid transport
FKQ53_RS02185	COG4191	Histidine kinase
FKQ53_RS02190	COG2204	response regulator
FKQ53_RS02210	COG0606	chelatase, subunit chli
FKQ53_RS02215	COG2960	long-chain fatty acid transporting porin activity
FKQ53_RS02225	COG0347	Belongs to the P(II) protein family
FKQ53_RS02230	COG0004	ammonium transporteR
FKQ53_RS02245	COG0189	ligase activity
FKQ53_RS02255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FKQ53_RS02260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FKQ53_RS02265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FKQ53_RS02270	COG0793	Belongs to the peptidase S41A family
FKQ53_RS02275	COG0588	phosphoglycerate mutase activity
FKQ53_RS02280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FKQ53_RS02285	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FKQ53_RS02290	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FKQ53_RS02300	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FKQ53_RS02315	COG2226	methyltransferase
FKQ53_RS02320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FKQ53_RS02325	COG2423	ornithine cyclodeaminase activity
FKQ53_RS02330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FKQ53_RS02340	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FKQ53_RS02355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FKQ53_RS02360	COG2771	luxR family
FKQ53_RS02375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FKQ53_RS02380	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FKQ53_RS02410	COG1612	heme a metabolic process
FKQ53_RS02420	COG1999	signal sequence binding
FKQ53_RS02430	COG1294	oxidase, subunit
FKQ53_RS02445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FKQ53_RS02455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FKQ53_RS02460	COG0625	glutathione transferase activity
FKQ53_RS02475	COG0612	Peptidase, M16
FKQ53_RS02480	COG0612	Peptidase, M16
FKQ53_RS02490	COG1131	(ABC) transporter
FKQ53_RS02495	COG0742	ribosomal rna small subunit methyltransferase
FKQ53_RS02500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FKQ53_RS02505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FKQ53_RS02510	COG0193	aminoacyl-tRNA hydrolase activity
FKQ53_RS02520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FKQ53_RS02535	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FKQ53_RS02550	COG1194	a g-specific adenine glycosylase
FKQ53_RS02555	COG1660	Displays ATPase and GTPase activities
FKQ53_RS02565	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FKQ53_RS02575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FKQ53_RS02580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FKQ53_RS02585	COG1137	ATPase activity
FKQ53_RS02600	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FKQ53_RS02615	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FKQ53_RS02630	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FKQ53_RS02635	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FKQ53_RS02645	COG3639	organic phosphonate transmembrane transporter activity
FKQ53_RS02650	COG3454	Phosphonate metabolism
FKQ53_RS02655	COG4778	phosphonate C-P lyase system protein PhnL
FKQ53_RS02660	COG4107	phosphonate C-P lyase system protein PhnK
FKQ53_RS02665	COG3627	carbon phosphorus lyase activity
FKQ53_RS02670	COG3626	phosphonate metabolism
FKQ53_RS02675	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FKQ53_RS02680	COG3624	Phosphonate C-P lyase system protein PhnG
FKQ53_RS02685	COG2188	Transcriptional regulator
FKQ53_RS02690	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FKQ53_RS02695	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FKQ53_RS02715	COG0477	Major facilitator Superfamily
FKQ53_RS02725	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FKQ53_RS02735	COG3842	ATPase activity
FKQ53_RS02740	COG1840	ABC-type Fe3 transport system, periplasmic component
FKQ53_RS02755	COG1012	belongs to the aldehyde dehydrogenase family
FKQ53_RS02760	COG1283	sodium-dependent phosphate transmembrane transporter activity
FKQ53_RS02800	COG2814	Major facilitator Superfamily
FKQ53_RS02805	COG0629	single-stranded DNA binding
FKQ53_RS02830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FKQ53_RS02915	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FKQ53_RS02920	COG2814	Major facilitator Superfamily
FKQ53_RS02930	COG0183	Belongs to the thiolase family
FKQ53_RS02945	COG1418	mRNA catabolic process
FKQ53_RS02965	COG1473	amidohydrolase
FKQ53_RS02970	COG1802	Transcriptional regulator
FKQ53_RS02980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKQ53_RS02985	COG1012	belongs to the aldehyde dehydrogenase family
FKQ53_RS03015	COG0625	glutathione transferase activity
FKQ53_RS03045	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS03050	COG0667	Aldo Keto reductase
FKQ53_RS03075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FKQ53_RS03085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKQ53_RS03090	COG0625	glutathione transferase activity
FKQ53_RS03120	COG0477	Major facilitator Superfamily
FKQ53_RS03145	COG0765	amino acid transport
FKQ53_RS03150	COG0010	Belongs to the arginase family
FKQ53_RS03155	COG1126	abc transporter atp-binding protein
FKQ53_RS03200	COG2610	gluconate transmembrane transporter activity
FKQ53_RS03210	COG1733	regulation of RNA biosynthetic process
FKQ53_RS03215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FKQ53_RS03220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FKQ53_RS03225	COG0656	L-ascorbic acid biosynthetic process
FKQ53_RS03230	COG3038	cytochrome b561
FKQ53_RS03235	COG4771	TonB-dependent receptor
FKQ53_RS03245	COG3047	cAMP biosynthetic process
FKQ53_RS03260	COG0247	lactate metabolic process
FKQ53_RS03265	COG1620	l-lactate permease
FKQ53_RS03270	COG2186	Transcriptional regulator
FKQ53_RS03275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FKQ53_RS03280	COG0583	DNA-binding transcription factor activity
FKQ53_RS03290	COG0625	glutathione transferase activity
FKQ53_RS03300	COG1448	Aminotransferase
FKQ53_RS03320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FKQ53_RS03325	COG0183	Belongs to the thiolase family
FKQ53_RS03330	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FKQ53_RS03340	COG1414	Transcriptional regulator
FKQ53_RS03390	COG2814	Major facilitator Superfamily
FKQ53_RS03405	COG0583	DNA-binding transcription factor activity
FKQ53_RS03410	COG0473	3-isopropylmalate dehydrogenase activity
FKQ53_RS03415	COG0583	DNA-binding transcription factor activity
FKQ53_RS03420	COG1902	pentaerythritol trinitrate reductase activity
FKQ53_RS03445	COG1414	Transcriptional regulator
FKQ53_RS03450	COG1414	Transcriptional regulator
FKQ53_RS03465	COG0730	response to heat
FKQ53_RS03495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FKQ53_RS03525	COG1113	amino acid transport
FKQ53_RS03530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKQ53_RS03535	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FKQ53_RS03540	COG4521	taurine ABC transporter
FKQ53_RS03545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKQ53_RS03555	COG0583	DNA-binding transcription factor activity
FKQ53_RS03590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKQ53_RS03600	COG0765	amino acid transport
FKQ53_RS03605	COG0165	Argininosuccinate lyase
FKQ53_RS03625	COG1454	alcohol dehydrogenase
FKQ53_RS03640	COG0583	DNA-binding transcription factor activity
FKQ53_RS03645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FKQ53_RS03655	COG0789	Transcriptional regulator
FKQ53_RS03665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FKQ53_RS03670	COG2814	Major facilitator Superfamily
FKQ53_RS03700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FKQ53_RS03710	COG0583	DNA-binding transcription factor activity
FKQ53_RS03715	COG0477	Major facilitator Superfamily
FKQ53_RS03735	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FKQ53_RS03755	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FKQ53_RS03755	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FKQ53_RS03765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FKQ53_RS03775	COG1238	metal cluster binding
FKQ53_RS03795	COG0025	NhaP-type Na H and K H
FKQ53_RS03810	COG2226	methyltransferase
FKQ53_RS03825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FKQ53_RS03850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FKQ53_RS03855	COG0494	nUDIX hydrolase
FKQ53_RS03860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKQ53_RS03870	COG1960	acyl-CoA dehydrogenase activity
FKQ53_RS03875	COG1250	3-hydroxyacyl-CoA dehydrogenase
FKQ53_RS03875	COG1024	Enoyl-CoA hydratase
FKQ53_RS03880	COG0183	Belongs to the thiolase family
FKQ53_RS03895	COG5265	(ABC) transporter
FKQ53_RS03905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FKQ53_RS03915	COG0765	amino acid transport
FKQ53_RS03920	COG0765	amino acid transport
FKQ53_RS03925	COG1126	abc transporter atp-binding protein
FKQ53_RS03930	COG0121	glutamine amidotransferase
FKQ53_RS03935	COG0418	dihydroorotase activity
FKQ53_RS03955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FKQ53_RS03960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FKQ53_RS03965	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FKQ53_RS03985	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FKQ53_RS03990	COG0739	heme binding
FKQ53_RS04005	COG1881	PFAM PEBP family protein
FKQ53_RS04010	COG0406	alpha-ribazole phosphatase activity
FKQ53_RS04020	COG2255	four-way junction helicase activity
FKQ53_RS04025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FKQ53_RS04030	COG1981	membrane
FKQ53_RS04055	COG0800	Aldolase
FKQ53_RS04065	COG3265	gluconokinase activity
FKQ53_RS04075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FKQ53_RS04105	COG0069	glutamate synthase activity
FKQ53_RS04110	COG2207	Transcriptional regulator
FKQ53_RS04175	COG2197	response regulator
FKQ53_RS04230	COG0741	lytic transglycosylase activity
FKQ53_RS04245	COG3909	cytochrome
FKQ53_RS04260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FKQ53_RS04265	COG1862	Preprotein translocase
FKQ53_RS04270	COG0343	queuine tRNA-ribosyltransferase activity
FKQ53_RS04275	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FKQ53_RS04280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FKQ53_RS04295	COG0753	catalase activity
FKQ53_RS04300	COG0352	thiamine-phosphate diphosphorylase activity
FKQ53_RS04305	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FKQ53_RS04310	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FKQ53_RS04330	COG1741	Belongs to the pirin family
FKQ53_RS04355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FKQ53_RS04380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FKQ53_RS04390	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FKQ53_RS04475	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS04480	COG0179	Fumarylacetoacetate (FAA) hydrolase
FKQ53_RS04485	COG0583	DNA-binding transcription factor activity
FKQ53_RS04495	COG0583	DNA-binding transcription factor activity
FKQ53_RS04500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ53_RS04505	COG1024	Enoyl-CoA hydratase
FKQ53_RS04515	COG2267	carboxylic ester hydrolase activity
FKQ53_RS04520	COG2814	Major facilitator Superfamily
FKQ53_RS04525	COG3971	2-oxopent-4-enoate hydratase activity
FKQ53_RS04530	COG3384	dioxygenase
FKQ53_RS04535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKQ53_RS04540	COG1414	Transcriptional regulator
FKQ53_RS04545	COG0583	DNA-binding transcription factor activity
FKQ53_RS04550	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FKQ53_RS04555	COG2271	Major facilitator Superfamily
FKQ53_RS04575	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FKQ53_RS04590	COG4214	carbohydrate transport
FKQ53_RS04605	COG1802	Transcriptional regulator
FKQ53_RS04610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FKQ53_RS04615	COG3210	domain, Protein
FKQ53_RS04625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FKQ53_RS04660	COG3328	transposase activity
FKQ53_RS04685	COG2826	transposase and inactivated derivatives, IS30 family
FKQ53_RS04745	COG2826	transposase and inactivated derivatives, IS30 family
FKQ53_RS04755	COG3328	transposase activity
FKQ53_RS04805	COG2826	transposase and inactivated derivatives, IS30 family
FKQ53_RS04830	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FKQ53_RS04840	COG4566	intracellular signal transduction
FKQ53_RS04870	COG1297	OPT oligopeptide transporter protein
FKQ53_RS04875	COG0477	Major facilitator Superfamily
FKQ53_RS04880	COG1686	Belongs to the peptidase S11 family
FKQ53_RS04910	COG1845	cytochrome c oxidase, subunit III
FKQ53_RS04915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FKQ53_RS04920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FKQ53_RS04925	COG0477	Major facilitator Superfamily
FKQ53_RS04935	COG0444	Belongs to the ABC transporter superfamily
FKQ53_RS04940	COG4608	Belongs to the ABC transporter superfamily
FKQ53_RS04945	COG0747	negative chemotaxis
FKQ53_RS04950	COG0601	transmembrane transport
FKQ53_RS04955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FKQ53_RS04970	COG3468	outer membrane autotransporter barrel domain protein
FKQ53_RS05015	COG2814	Major facilitator Superfamily
FKQ53_RS05020	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS05025	COG1024	Enoyl-CoA hydratase
FKQ53_RS05030	COG1012	belongs to the aldehyde dehydrogenase family
FKQ53_RS05035	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ53_RS05040	COG1960	acyl-CoA dehydrogenase activity
FKQ53_RS05050	COG0583	DNA-binding transcription factor activity
FKQ53_RS05055	COG3485	protocatechuate 3,4-dioxygenase
FKQ53_RS05060	COG3485	protocatechuate 3,4-dioxygenase
FKQ53_RS05070	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FKQ53_RS05075	COG0596	Alpha beta hydrolase
FKQ53_RS05080	COG1917	Cupin 2, conserved barrel domain protein
FKQ53_RS05080	COG2207	Transcriptional regulator
FKQ53_RS05090	COG2814	Major facilitator Superfamily
FKQ53_RS05125	COG3634	alkyl hydroperoxide reductase activity
FKQ53_RS05140	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FKQ53_RS05145	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FKQ53_RS05155	COG1850	ribulose-bisphosphate carboxylase activity
FKQ53_RS05165	COG1414	Transcriptional regulator
FKQ53_RS05170	COG1012	belongs to the aldehyde dehydrogenase family
FKQ53_RS05175	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ53_RS05180	COG2271	Major facilitator Superfamily
FKQ53_RS05185	COG4149	molybdate abc transporter
FKQ53_RS05195	COG3842	ATPase activity
FKQ53_RS05200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS05205	COG2205	protein histidine kinase activity
FKQ53_RS05210	COG0745	RESPONSE REGULATOR receiver
FKQ53_RS05230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKQ53_RS05265	COG3237	CsbD-like
FKQ53_RS05270	COG4585	Histidine kinase
FKQ53_RS05295	COG2201	protein-glutamate methylesterase activity
FKQ53_RS05305	COG2011	ABC-type metal ion transport system permease component
FKQ53_RS05315	COG5001	Diguanylate cyclase
FKQ53_RS05315	COG3300	MHYT domain
FKQ53_RS05320	COG0531	amino acid
FKQ53_RS05330	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FKQ53_RS05340	COG0436	Aminotransferase
FKQ53_RS05345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FKQ53_RS05350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FKQ53_RS05360	COG0640	Transcriptional regulator
FKQ53_RS05405	COG3971	2-oxopent-4-enoate hydratase activity
FKQ53_RS05415	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FKQ53_RS05415	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FKQ53_RS05430	COG1704	LemA family
FKQ53_RS05435	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FKQ53_RS05440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FKQ53_RS05445	COG0671	phosphoesterase, PA-phosphatase related
FKQ53_RS05450	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FKQ53_RS05460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FKQ53_RS05470	COG0837	glucose binding
FKQ53_RS05470	COG1737	Transcriptional regulator
FKQ53_RS05480	COG3360	Dodecin
FKQ53_RS05485	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FKQ53_RS05490	COG0443	Heat shock 70 kDa protein
FKQ53_RS05495	COG2814	Major facilitator Superfamily
FKQ53_RS05505	COG0640	Transcriptional regulator
FKQ53_RS05525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKQ53_RS05540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKQ53_RS05560	COG1414	Transcriptional regulator
FKQ53_RS05565	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS05570	COG0028	Belongs to the TPP enzyme family
FKQ53_RS05580	COG1012	belongs to the aldehyde dehydrogenase family
FKQ53_RS05585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FKQ53_RS05620	COG0386	Belongs to the glutathione peroxidase family
FKQ53_RS05655	COG2072	flavoprotein involved in K transport
FKQ53_RS05665	COG2271	Major facilitator Superfamily
FKQ53_RS05670	COG2721	sulfolactate sulfo-lyase activity
FKQ53_RS05680	COG2084	Dehydrogenase
FKQ53_RS05690	COG0583	DNA-binding transcription factor activity
FKQ53_RS05695	COG0730	response to heat
FKQ53_RS05700	COG0175	sulfate reduction
FKQ53_RS05710	COG2895	sulfate adenylyltransferase (ATP) activity
FKQ53_RS05715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FKQ53_RS05715	COG1648	precorrin-2 dehydrogenase activity
FKQ53_RS05735	COG0795	lipopolysaccharide-transporting ATPase activity
FKQ53_RS05740	COG0795	lipopolysaccharide-transporting ATPase activity
FKQ53_RS05745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FKQ53_RS05770	COG0129	dihydroxy-acid dehydratase activity
FKQ53_RS05775	COG0583	DNA-binding transcription factor activity
FKQ53_RS05780	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FKQ53_RS05785	COG1802	Transcriptional regulator
FKQ53_RS05790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FKQ53_RS05810	COG1024	Enoyl-CoA hydratase
FKQ53_RS05815	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ53_RS05850	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FKQ53_RS05860	COG0287	Prephenate dehydrogenase
FKQ53_RS05865	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FKQ53_RS05870	COG1914	H( )-stimulated, divalent metal cation uptake system
FKQ53_RS05875	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FKQ53_RS05895	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FKQ53_RS05905	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FKQ53_RS05910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FKQ53_RS05925	COG2951	lytic endotransglycosylase activity
FKQ53_RS05935	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FKQ53_RS05945	COG2267	carboxylic ester hydrolase activity
FKQ53_RS05960	COG1960	acyl-CoA dehydrogenase activity
FKQ53_RS05980	COG4206	TonB-dependent receptor
FKQ53_RS05985	COG4139	cobalamin transport
FKQ53_RS05990	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FKQ53_RS06000	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FKQ53_RS06005	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FKQ53_RS06015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FKQ53_RS06040	COG1492	cobalamin metabolic process
FKQ53_RS06045	COG0489	protein tyrosine kinase activity
FKQ53_RS06050	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FKQ53_RS06075	COG2911	Protein conserved in bacteria
FKQ53_RS06090	COG1522	sequence-specific DNA binding
FKQ53_RS06100	COG2885	chlorophyll binding
FKQ53_RS06105	COG0489	protein tyrosine kinase activity
FKQ53_RS06110	COG0717	Belongs to the dCTP deaminase family
FKQ53_RS06120	COG0786	glutamate:sodium symporter activity
FKQ53_RS06125	COG0165	Argininosuccinate lyase
FKQ53_RS06140	COG0181	hydroxymethylbilane synthase activity
FKQ53_RS06165	COG0477	Major facilitator Superfamily
FKQ53_RS06170	COG2271	Major facilitator Superfamily
FKQ53_RS06185	COG0277	FAD linked oxidase domain protein
FKQ53_RS06200	COG1176	ABC-type spermidine putrescine transport system, permease component I
FKQ53_RS06205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKQ53_RS06220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FKQ53_RS06230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FKQ53_RS06230	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FKQ53_RS06240	COG2860	membrane
FKQ53_RS06245	COG1193	negative regulation of DNA recombination
FKQ53_RS06250	COG0492	ferredoxin-NADP+ reductase activity
FKQ53_RS06255	COG1674	ftsk spoiiie
FKQ53_RS06260	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FKQ53_RS06265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FKQ53_RS06270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FKQ53_RS06290	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FKQ53_RS06290	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FKQ53_RS06305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FKQ53_RS06310	COG1960	acyl-CoA dehydrogenase activity
FKQ53_RS06315	COG2159	amidohydrolase
FKQ53_RS06320	COG2814	Major facilitator Superfamily
FKQ53_RS06325	COG1454	alcohol dehydrogenase
FKQ53_RS06330	COG3485	protocatechuate 3,4-dioxygenase
FKQ53_RS06335	COG0477	Major facilitator Superfamily
FKQ53_RS06350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ53_RS06360	COG4948	Mandelate Racemase Muconate Lactonizing
FKQ53_RS06365	COG0583	DNA-binding transcription factor activity
FKQ53_RS06375	COG0583	DNA-binding transcription factor activity
FKQ53_RS06380	COG2814	Major facilitator Superfamily
FKQ53_RS06445	COG2610	gluconate transmembrane transporter activity
FKQ53_RS06450	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS06465	COG1349	DNA-binding transcription factor activity
FKQ53_RS06475	COG3395	kinase activity
FKQ53_RS06480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FKQ53_RS06490	COG0235	Class ii aldolase
FKQ53_RS06500	COG2271	Major facilitator Superfamily
FKQ53_RS06515	COG2860	membrane
FKQ53_RS06520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKQ53_RS06530	COG1538	Outer membrane efflux protein
FKQ53_RS06535	COG5002	protein histidine kinase activity
FKQ53_RS06540	COG0745	RESPONSE REGULATOR receiver
FKQ53_RS06550	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FKQ53_RS06555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FKQ53_RS06560	COG1845	cytochrome c oxidase, subunit III
FKQ53_RS06580	COG2070	2-Nitropropane dioxygenase
FKQ53_RS06590	COG1562	ergosterol biosynthetic process
FKQ53_RS06595	COG1562	ergosterol biosynthetic process
FKQ53_RS06600	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FKQ53_RS06605	COG1657	PFAM Prenyltransferase squalene oxidase
FKQ53_RS06615	COG0463	Glycosyl transferase, family 2
FKQ53_RS06620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FKQ53_RS06645	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FKQ53_RS06650	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FKQ53_RS06655	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
FKQ53_RS06655	COG0028	Belongs to the TPP enzyme family
FKQ53_RS06665	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FKQ53_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS06695	COG2375	cellular response to nickel ion
FKQ53_RS06700	COG1695	Transcriptional regulator
FKQ53_RS06705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKQ53_RS06730	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FKQ53_RS06735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FKQ53_RS06740	COG0688	phosphatidylethanolamine metabolic process
FKQ53_RS06750	COG2271	Major facilitator Superfamily
FKQ53_RS06760	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FKQ53_RS06770	COG1414	Transcriptional regulator
FKQ53_RS06785	COG0583	DNA-binding transcription factor activity
FKQ53_RS06790	COG2814	Major facilitator Superfamily
FKQ53_RS06795	COG0004	ammonium transporteR
FKQ53_RS06805	COG2186	Transcriptional regulator
FKQ53_RS06810	COG0277	FAD linked oxidase domain protein
FKQ53_RS06820	COG2814	Major facilitator Superfamily
FKQ53_RS06835	COG0579	oxidoreductase
FKQ53_RS06845	COG1414	Transcriptional regulator
FKQ53_RS06850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS06855	COG2271	Major facilitator Superfamily
FKQ53_RS06870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FKQ53_RS06875	COG1960	acyl-CoA dehydrogenase activity
FKQ53_RS06880	COG1024	Enoyl-CoA hydratase
FKQ53_RS06900	COG1446	asparaginase
FKQ53_RS06905	COG4172	Belongs to the ABC transporter superfamily
FKQ53_RS06920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FKQ53_RS06945	COG3842	ATPase activity
FKQ53_RS06950	COG1653	transport
FKQ53_RS06955	COG1175	transmembrane transport
FKQ53_RS06965	COG0589	response to stress
FKQ53_RS06985	COG0534	Mate efflux family protein
FKQ53_RS06995	COG2985	domain, Protein
FKQ53_RS07000	COG2985	domain, Protein
FKQ53_RS07035	COG3383	formate dehydrogenase (NAD+) activity
FKQ53_RS07045	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FKQ53_RS07050	COG1802	Transcriptional regulator
FKQ53_RS07060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FKQ53_RS07080	COG4191	Histidine kinase
FKQ53_RS07090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ53_RS07095	COG0179	Fumarylacetoacetate (FAA) hydrolase
FKQ53_RS07105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FKQ53_RS07125	COG0583	DNA-binding transcription factor activity
FKQ53_RS07145	COG1802	Transcriptional regulator
FKQ53_RS07155	COG1024	Enoyl-CoA hydratase
FKQ53_RS07160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ53_RS07165	COG3387	PFAM Glycoside hydrolase 15-related
FKQ53_RS07180	COG2197	response regulator
FKQ53_RS07185	COG2205	protein histidine kinase activity
FKQ53_RS07195	COG3008	intermembrane lipid transfer
FKQ53_RS07200	COG2995	paraquat-inducible protein a
FKQ53_RS07215	COG0437	4 iron, 4 sulfur cluster binding
FKQ53_RS07220	COG2864	formate dehydrogenase
FKQ53_RS07235	COG3276	selenocysteine insertion sequence binding
FKQ53_RS07270	COG1120	ATPase activity
FKQ53_RS07285	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FKQ53_RS07310	COG1104	cysteine desulfurase activity
FKQ53_RS07315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FKQ53_RS07320	COG2368	4-hydroxyphenylacetate
FKQ53_RS07340	COG1137	ATPase activity
FKQ53_RS07360	COG1959	2 iron, 2 sulfur cluster binding
FKQ53_RS07375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS07385	COG1349	DNA-binding transcription factor activity
FKQ53_RS07395	COG1522	sequence-specific DNA binding
FKQ53_RS07405	COG0583	DNA-binding transcription factor activity
FKQ53_RS07410	COG3048	D-serine ammonia-lyase activity
FKQ53_RS07415	COG2271	Major facilitator Superfamily
FKQ53_RS07435	COG2814	Major facilitator Superfamily
FKQ53_RS07480	COG2391	methyltransferase activity
FKQ53_RS07495	COG0823	Involved in the tonB-independent uptake of proteins
FKQ53_RS07505	COG0848	biopolymer transport protein
FKQ53_RS07515	COG0824	Thioesterase
FKQ53_RS07520	COG2084	Dehydrogenase
FKQ53_RS07525	COG1414	Transcriptional regulator
FKQ53_RS07575	COG3328	transposase activity
FKQ53_RS07610	COG0543	2 iron, 2 sulfur cluster binding
FKQ53_RS07615	COG2814	Major facilitator Superfamily
FKQ53_RS07660	COG0583	DNA-binding transcription factor activity
FKQ53_RS07700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FKQ53_RS07705	COG0686	Belongs to the AlaDH PNT family
FKQ53_RS07710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FKQ53_RS07745	COG0228	four-way junction DNA binding
FKQ53_RS07750	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FKQ53_RS07755	COG0336	Belongs to the RNA methyltransferase TrmD family
FKQ53_RS07760	COG0335	large ribosomal subunit rRNA binding
FKQ53_RS07770	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FKQ53_RS07775	COG1162	GTPase activity
FKQ53_RS07780	COG0501	Belongs to the peptidase M48B family
FKQ53_RS07785	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FKQ53_RS07790	COG0521	Mo-molybdopterin cofactor biosynthetic process
FKQ53_RS07800	COG0312	modulator of DNA gyrase
FKQ53_RS07830	COG2203	Gaf domain
FKQ53_RS07830	COG5001	Diguanylate cyclase
FKQ53_RS07830	COG4251	negative regulation of phosphorylation
FKQ53_RS07830	COG3706	GGDEF domain
FKQ53_RS07840	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FKQ53_RS07845	COG3842	ATPase activity
FKQ53_RS07850	COG1178	ABC-type Fe3 transport system permease component
FKQ53_RS07855	COG0583	DNA-binding transcription factor activity
FKQ53_RS07865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ53_RS07870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ53_RS07880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FKQ53_RS07895	COG0415	Belongs to the DNA photolyase family
FKQ53_RS07905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKQ53_RS07925	COG2153	protein acetylation
FKQ53_RS07930	COG0488	(ABC) transporter
FKQ53_RS07945	COG0741	lytic transglycosylase activity
FKQ53_RS07960	COG0583	DNA-binding transcription factor activity
FKQ53_RS07965	COG2814	Major facilitator Superfamily
FKQ53_RS07970	COG0251	oxidation-reduction process
FKQ53_RS07975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKQ53_RS07980	COG0697	spore germination
FKQ53_RS08015	COG4106	trans-aconitate 2-methyltransferase activity
FKQ53_RS08025	COG3135	benzoate transporter
FKQ53_RS08035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FKQ53_RS08060	COG0778	Nitroreductase
FKQ53_RS08065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FKQ53_RS08070	COG2878	Part of a membrane complex involved in electron transport
FKQ53_RS08075	COG1309	transcriptional regulator
FKQ53_RS08090	COG0556	nucleotide-excision repair
FKQ53_RS08110	COG2267	carboxylic ester hydrolase activity
FKQ53_RS08125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FKQ53_RS08140	COG1104	cysteine desulfurase activity
FKQ53_RS08145	COG0822	iron-sulfur transferase activity
FKQ53_RS08150	COG0316	Belongs to the HesB IscA family
FKQ53_RS08160	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FKQ53_RS08195	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FKQ53_RS08220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FKQ53_RS08240	COG0084	hydrolase, TatD family'
FKQ53_RS08255	COG2267	carboxylic ester hydrolase activity
FKQ53_RS08260	COG0504	CTP synthase activity
FKQ53_RS08265	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FKQ53_RS08270	COG0148	phosphopyruvate hydratase activity
FKQ53_RS08275	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FKQ53_RS08285	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FKQ53_RS08295	COG2833	Protein of unknown function (DUF455)
FKQ53_RS08300	COG2267	carboxylic ester hydrolase activity
FKQ53_RS08305	COG0613	PHP domain protein
FKQ53_RS08310	COG0009	L-threonylcarbamoyladenylate synthase
FKQ53_RS08315	COG1994	Peptidase M50
FKQ53_RS08320	COG0180	Tryptophanyl-tRNA synthetase
FKQ53_RS08330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKQ53_RS08335	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FKQ53_RS08350	COG2850	peptidyl-arginine hydroxylation
FKQ53_RS08380	COG3321	synthase
FKQ53_RS08380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FKQ53_RS08380	COG0604	alcohol dehydrogenase
FKQ53_RS08380	COG4221	oxidoreductase activity
FKQ53_RS08385	COG0149	triose-phosphate isomerase activity
FKQ53_RS08410	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FKQ53_RS08420	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FKQ53_RS08430	COG1034	ATP synthesis coupled electron transport
FKQ53_RS08435	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FKQ53_RS08440	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FKQ53_RS08450	COG0713	ATP synthesis coupled electron transport
FKQ53_RS08465	COG1007	ATP synthesis coupled electron transport
FKQ53_RS08500	COG0625	glutathione transferase activity
FKQ53_RS08520	COG1024	Enoyl-CoA hydratase
FKQ53_RS08525	COG1250	3-hydroxyacyl-CoA dehydrogenase
FKQ53_RS08530	COG0625	glutathione transferase activity
FKQ53_RS08540	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FKQ53_RS08545	COG2814	Major facilitator Superfamily
FKQ53_RS08555	COG0436	Aminotransferase
FKQ53_RS08565	COG3022	response to hydroperoxide
FKQ53_RS08570	COG2866	Carboxypeptidase
FKQ53_RS08580	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FKQ53_RS08590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FKQ53_RS08600	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FKQ53_RS08610	COG0039	L-malate dehydrogenase activity
FKQ53_RS08615	COG2188	Transcriptional regulator
FKQ53_RS08630	COG1053	succinate dehydrogenase
FKQ53_RS08635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FKQ53_RS08640	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FKQ53_RS08645	COG0372	Belongs to the citrate synthase family
FKQ53_RS08650	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FKQ53_RS08660	COG0066	3-isopropylmalate dehydratase activity
FKQ53_RS08665	COG0473	3-isopropylmalate dehydrogenase activity
FKQ53_RS08670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FKQ53_RS08680	COG0101	tRNA pseudouridine synthase activity
FKQ53_RS08685	COG0135	phosphoribosylanthranilate isomerase activity
FKQ53_RS08690	COG0133	tryptophan synthase activity
FKQ53_RS08700	COG0159	tryptophan synthase activity
FKQ53_RS08705	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FKQ53_RS08710	COG0285	dihydrofolate synthase activity
FKQ53_RS08735	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FKQ53_RS08745	COG2194	sulfuric ester hydrolase activity
FKQ53_RS08750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKQ53_RS08760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKQ53_RS08765	COG0483	inositol monophosphate 1-phosphatase activity
FKQ53_RS08775	COG1045	serine acetyltransferase
FKQ53_RS08780	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKQ53_RS08805	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FKQ53_RS08815	COG0037	tRNA processing
FKQ53_RS08820	COG0527	aspartate kinase activity
FKQ53_RS08845	COG4166	transmembrane transport
FKQ53_RS08850	COG4174	ABC transporter (Permease)
FKQ53_RS08855	COG4239	(ABC) transporter, permease
FKQ53_RS08860	COG4172	Belongs to the ABC transporter superfamily
FKQ53_RS08865	COG0791	NLP P60 protein
FKQ53_RS08870	COG1752	Esterase of the alpha-beta hydrolase superfamily
FKQ53_RS08875	COG1840	ABC-type Fe3 transport system, periplasmic component
FKQ53_RS08885	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FKQ53_RS08905	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FKQ53_RS08915	COG2204	response regulator
FKQ53_RS08960	COG2197	response regulator
FKQ53_RS08965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ53_RS08980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKQ53_RS08985	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FKQ53_RS09020	COG0105	UTP biosynthetic process
FKQ53_RS09025	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FKQ53_RS09040	COG0124	histidyl-tRNA synthetase
FKQ53_RS09045	COG2976	Protein conserved in bacteria
FKQ53_RS09055	COG1160	GTP binding
FKQ53_RS09060	COG1923	regulation of RNA biosynthetic process
FKQ53_RS09065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FKQ53_RS09070	COG0330	HflC and HflK could
FKQ53_RS09075	COG0330	HflC and HflK could
FKQ53_RS09080	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FKQ53_RS09085	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FKQ53_RS09095	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FKQ53_RS09105	COG0339	signal peptide processing
FKQ53_RS09110	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FKQ53_RS09115	COG4566	intracellular signal transduction
FKQ53_RS09125	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FKQ53_RS09130	COG0508	dehydrogenase complex catalyzes the overall conversion of
FKQ53_RS09135	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FKQ53_RS09140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKQ53_RS09150	COG0123	including yeast histone deacetylase and acetoin utilization protein
FKQ53_RS09170	COG1414	Transcriptional regulator
FKQ53_RS09185	COG1139	Iron-sulfur cluster binding protein
FKQ53_RS09190	COG0765	amino acid transport
FKQ53_RS09195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKQ53_RS09200	COG0167	dihydroorotate dehydrogenase activity
FKQ53_RS09205	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FKQ53_RS09210	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FKQ53_RS09235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FKQ53_RS09355	COG0305	Participates in initiation and elongation during chromosome replication
FKQ53_RS09415	COG0740	serine-type endopeptidase activity
FKQ53_RS09585	COG3328	transposase activity
FKQ53_RS09635	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FKQ53_RS09685	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FKQ53_RS09690	COG0435	Glutathione S-transferase
FKQ53_RS09695	COG1278	Cold shock
FKQ53_RS09710	COG0679	Auxin Efflux Carrier
FKQ53_RS09735	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FKQ53_RS09740	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FKQ53_RS09745	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FKQ53_RS09750	COG0840	transmembrane signaling receptor activity
FKQ53_RS09805	COG1280	lysine exporter protein (LysE YggA)
FKQ53_RS09815	COG0174	glutamine synthetase
FKQ53_RS09850	COG0307	riboflavin synthase, alpha
FKQ53_RS09865	COG0387	Pfam Sodium calcium exchanger
FKQ53_RS09870	COG2186	Transcriptional regulator
FKQ53_RS09875	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS09880	COG0179	Fumarylacetoacetate (FAA) hydrolase
FKQ53_RS09885	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS09890	COG2818	Glycosylase
FKQ53_RS09895	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FKQ53_RS09900	COG1187	pseudouridine synthase activity
FKQ53_RS09905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKQ53_RS09910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FKQ53_RS09915	COG1116	anion transmembrane transporter activity
FKQ53_RS09930	COG2207	Transcriptional regulator
FKQ53_RS09940	COG0583	DNA-binding transcription factor activity
FKQ53_RS09950	COG0557	exoribonuclease II activity
FKQ53_RS09955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKQ53_RS09980	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FKQ53_RS09995	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FKQ53_RS09995	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FKQ53_RS10000	COG1643	Atp-dependent helicase
FKQ53_RS10015	COG1546	Belongs to the CinA family
FKQ53_RS10015	COG1058	Belongs to the CinA family
FKQ53_RS10025	COG0583	DNA-binding transcription factor activity
FKQ53_RS10035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKQ53_RS10040	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FKQ53_RS10045	COG1187	pseudouridine synthase activity
FKQ53_RS10050	COG0779	Required for maturation of 30S ribosomal subunits
FKQ53_RS10055	COG0195	Participates in both transcription termination and antitermination
FKQ53_RS10055	COG2251	uridine kinase activity
FKQ53_RS10065	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FKQ53_RS10070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FKQ53_RS10085	COG2814	Major facilitator Superfamily
FKQ53_RS10090	COG1566	PFAM secretion protein HlyD family protein
FKQ53_RS10125	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FKQ53_RS10130	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FKQ53_RS10135	COG4208	sulfate ABC transporter
FKQ53_RS10140	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FKQ53_RS10145	COG0583	DNA-binding transcription factor activity
FKQ53_RS10150	COG0252	asparaginase activity
FKQ53_RS10155	COG2084	Dehydrogenase
FKQ53_RS10160	COG3622	Belongs to the hyi family
FKQ53_RS10165	COG3960	tartronate-semialdehyde synthase activity
FKQ53_RS10170	COG0583	DNA-binding transcription factor activity
FKQ53_RS10180	COG2965	DNA replication, synthesis of RNA primer
FKQ53_RS10190	COG0359	binds to the 23S rRNA
FKQ53_RS10205	COG0306	phosphate transporter
FKQ53_RS10215	COG0791	NLP P60 protein
FKQ53_RS10220	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FKQ53_RS10225	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FKQ53_RS10235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FKQ53_RS10235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FKQ53_RS10245	COG1215	transferase activity, transferring glycosyl groups
FKQ53_RS10250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FKQ53_RS10255	COG2076	Multidrug Resistance protein
FKQ53_RS10260	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FKQ53_RS10270	COG0436	Aminotransferase
FKQ53_RS10285	COG0303	'Molybdopterin
FKQ53_RS10295	COG0314	molybdopterin synthase activity
FKQ53_RS10305	COG0542	response to heat
FKQ53_RS10310	COG0667	Aldo Keto reductase
FKQ53_RS10315	COG0583	DNA-binding transcription factor activity
FKQ53_RS10325	COG3275	phosphorelay sensor kinase activity
FKQ53_RS10345	COG2224	Isocitrate lyase
FKQ53_RS10355	COG0583	DNA-binding transcription factor activity
FKQ53_RS10365	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FKQ53_RS10375	COG0513	Belongs to the DEAD box helicase family
FKQ53_RS10380	COG1214	PFAM Peptidase M22, glycoprotease
FKQ53_RS10385	COG0456	acetyltransferase
FKQ53_RS10385	COG1214	PFAM Peptidase M22, glycoprotease
FKQ53_RS10390	COG1573	uracil-dna glycosylase
FKQ53_RS10400	COG0351	phosphomethylpyrimidine kinase
FKQ53_RS10405	COG0477	Major facilitator Superfamily
FKQ53_RS10410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FKQ53_RS10420	COG0488	(ABC) transporter
FKQ53_RS10430	COG2890	protein-(glutamine-N5) methyltransferase activity
FKQ53_RS10435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FKQ53_RS10440	COG1393	Belongs to the ArsC family
FKQ53_RS10445	COG2171	N-acyltransferase activity
FKQ53_RS10470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FKQ53_RS10475	COG0242	peptide deformylase activity
FKQ53_RS10480	COG1187	pseudouridine synthase activity
FKQ53_RS10490	COG0024	Methionine aminopeptidase
FKQ53_RS10495	COG0052	Belongs to the universal ribosomal protein uS2 family
FKQ53_RS10500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FKQ53_RS10515	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FKQ53_RS10525	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FKQ53_RS10530	COG0750	zinc metalloprotease
FKQ53_RS10545	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKQ53_RS10570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKQ53_RS10575	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FKQ53_RS10590	COG0330	HflC and HflK could
FKQ53_RS10595	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FKQ53_RS10600	COG2867	negative regulation of translational initiation
FKQ53_RS10605	COG2914	Belongs to the UPF0125 (RnfH) family
FKQ53_RS10625	COG0519	Catalyzes the synthesis of GMP from XMP
FKQ53_RS10625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FKQ53_RS10640	COG0210	DNA helicase
FKQ53_RS10670	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS10675	COG0583	DNA-binding transcription factor activity
FKQ53_RS10700	COG1619	proteins homologs of microcin C7 resistance protein MccF
FKQ53_RS10710	COG3195	allantoin biosynthetic process
FKQ53_RS10710	COG3648	Uricase
FKQ53_RS10715	COG4266	Belongs to the allantoicase family
FKQ53_RS10725	COG2308	Evidence 4 Homologs of previously reported genes of
FKQ53_RS10760	COG2233	PERMEase
FKQ53_RS10770	COG0583	DNA-binding transcription factor activity
FKQ53_RS10775	COG3845	ABC transporter
FKQ53_RS10780	COG4603	Belongs to the binding-protein-dependent transport system permease family
FKQ53_RS10785	COG1079	Belongs to the binding-protein-dependent transport system permease family
FKQ53_RS10800	COG0488	(ABC) transporter
FKQ53_RS10820	COG3706	GGDEF domain
FKQ53_RS10855	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FKQ53_RS10895	COG0243	molybdopterin cofactor binding
FKQ53_RS10915	COG3383	formate dehydrogenase (NAD+) activity
FKQ53_RS10920	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FKQ53_RS10945	COG0733	neurotransmitter:sodium symporter activity
FKQ53_RS10960	COG0471	metal ion transport
FKQ53_RS10965	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FKQ53_RS10970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FKQ53_RS10975	COG1024	Enoyl-CoA hydratase
FKQ53_RS10985	COG3842	ATPase activity
FKQ53_RS10990	COG1176	ABC-type spermidine putrescine transport system, permease component I
FKQ53_RS11020	COG2814	Major facilitator Superfamily
FKQ53_RS11035	COG5002	protein histidine kinase activity
FKQ53_RS11035	COG5001	Diguanylate cyclase
FKQ53_RS11045	COG1674	ftsk spoiiie
FKQ53_RS11070	COG0604	alcohol dehydrogenase
FKQ53_RS11080	COG2070	2-Nitropropane dioxygenase
FKQ53_RS11120	COG3264	Mechanosensitive ion channel
FKQ53_RS11120	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FKQ53_RS11130	COG2203	Gaf domain
FKQ53_RS11130	COG5001	Diguanylate cyclase
FKQ53_RS11130	COG4251	negative regulation of phosphorylation
FKQ53_RS11130	COG3706	GGDEF domain
FKQ53_RS11160	COG4572	Cation transport regulator
FKQ53_RS11165	COG2814	Major facilitator Superfamily
FKQ53_RS11170	COG0534	Mate efflux family protein
FKQ53_RS11180	COG3550	peptidyl-serine autophosphorylation
FKQ53_RS11200	COG5002	protein histidine kinase activity
FKQ53_RS11210	COG1538	Outer membrane efflux protein
FKQ53_RS11225	COG2837	iron assimilation
FKQ53_RS11250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FKQ53_RS11260	COG3119	arylsulfatase activity
FKQ53_RS11295	COG1902	pentaerythritol trinitrate reductase activity
FKQ53_RS11295	COG0446	pyridine nucleotide-disulphide oxidoreductase
FKQ53_RS11300	COG3706	GGDEF domain
FKQ53_RS11305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ53_RS11310	COG0372	Belongs to the citrate synthase family
FKQ53_RS11335	COG0625	glutathione transferase activity
FKQ53_RS11350	COG0798	PFAM Bile acid sodium symporter
FKQ53_RS11370	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FKQ53_RS11415	COG0384	phenazine biosynthesis protein PhzF
FKQ53_RS11425	COG1396	sequence-specific DNA binding
FKQ53_RS11430	COG0477	Major facilitator Superfamily
FKQ53_RS11455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ53_RS11470	COG2814	Major facilitator Superfamily
FKQ53_RS11475	COG0154	amidase activity
FKQ53_RS11495	COG0583	DNA-binding transcription factor activity
FKQ53_RS11520	COG3040	lipid binding
FKQ53_RS11535	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FKQ53_RS11545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FKQ53_RS11565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FKQ53_RS11600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FKQ53_RS11600	COG1796	DNA polymerase
FKQ53_RS11680	COG1914	H( )-stimulated, divalent metal cation uptake system
FKQ53_RS11695	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FKQ53_RS11700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FKQ53_RS11705	COG1063	alcohol dehydrogenase
FKQ53_RS11725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKQ53_RS11735	COG0589	response to stress
FKQ53_RS11740	COG0589	response to stress
FKQ53_RS11745	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FKQ53_RS11755	COG0477	Major facilitator Superfamily
FKQ53_RS11760	COG5295	Hep Hag repeat protein
FKQ53_RS11765	COG0583	DNA-binding transcription factor activity
FKQ53_RS11775	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FKQ53_RS11810	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FKQ53_RS11825	COG1196	nuclear chromosome segregation
FKQ53_RS11825	COG0739	heme binding
FKQ53_RS11825	COG0741	lytic transglycosylase activity
FKQ53_RS11830	COG2885	chlorophyll binding
FKQ53_RS11865	COG4964	Belongs to the GSP D family
FKQ53_RS11915	COG2186	Transcriptional regulator
FKQ53_RS11935	COG2423	ornithine cyclodeaminase activity
FKQ53_RS11940	COG0543	2 iron, 2 sulfur cluster binding
FKQ53_RS11960	COG2814	Major facilitator Superfamily
FKQ53_RS11965	COG0154	amidase activity
FKQ53_RS11970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FKQ53_RS11995	COG2181	nitrate reductase activity
FKQ53_RS12000	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FKQ53_RS12005	COG1140	nitrate reductase beta subunit
FKQ53_RS12010	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FKQ53_RS12015	COG1132	(ABC) transporter
FKQ53_RS12030	COG0789	Transcriptional regulator
FKQ53_RS12035	COG1045	serine acetyltransferase
FKQ53_RS12040	COG0583	DNA-binding transcription factor activity
FKQ53_RS12045	COG3493	citrate carrier protein
FKQ53_RS12050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ53_RS12055	COG2301	Belongs to the HpcH HpaI aldolase family
FKQ53_RS12075	COG0688	phosphatidylethanolamine metabolic process
FKQ53_RS12080	COG0583	DNA-binding transcription factor activity
FKQ53_RS12085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FKQ53_RS12105	COG2188	Transcriptional regulator
FKQ53_RS12115	COG2986	histidine ammonia-lyase
FKQ53_RS12120	COG1113	amino acid transport
FKQ53_RS12130	COG0583	DNA-binding transcription factor activity
FKQ53_RS12140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKQ53_RS12170	COG3791	Glutathione-dependent formaldehyde-activating
FKQ53_RS12185	COG0477	Major facilitator Superfamily
FKQ53_RS12190	COG1113	amino acid transport
FKQ53_RS12200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKQ53_RS12205	COG0657	acetylesterase activity
FKQ53_RS12215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKQ53_RS12230	COG0179	Fumarylacetoacetate (FAA) hydrolase
FKQ53_RS12235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FKQ53_RS12255	COG2186	Transcriptional regulator
FKQ53_RS12275	COG3257	ureidoglycine aminohydrolase activity
FKQ53_RS12280	COG0583	DNA-binding transcription factor activity
FKQ53_RS12295	COG0402	S-adenosylhomocysteine deaminase activity
FKQ53_RS12300	COG2197	response regulator
FKQ53_RS12340	COG2814	Major facilitator Superfamily
FKQ53_RS12345	COG1022	Amp-dependent synthetase and ligase
FKQ53_RS12360	COG1250	3-hydroxyacyl-CoA dehydrogenase
FKQ53_RS12365	COG1024	Enoyl-CoA hydratase
FKQ53_RS12370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FKQ53_RS12380	COG5001	Diguanylate cyclase
FKQ53_RS12380	COG5002	protein histidine kinase activity
FKQ53_RS12380	COG3447	MASE1 domain protein
FKQ53_RS12390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKQ53_RS12410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKQ53_RS12415	COG0840	transmembrane signaling receptor activity
FKQ53_RS12425	COG4106	trans-aconitate 2-methyltransferase activity
FKQ53_RS12455	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS12465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKQ53_RS12495	COG0667	Aldo Keto reductase
FKQ53_RS12505	COG1215	transferase activity, transferring glycosyl groups
FKQ53_RS12515	COG0457	Tetratricopeptide repeat
FKQ53_RS12520	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FKQ53_RS12525	COG1215	transferase activity, transferring glycosyl groups
FKQ53_RS12545	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FKQ53_RS12555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FKQ53_RS12585	COG1012	belongs to the aldehyde dehydrogenase family
FKQ53_RS12610	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FKQ53_RS12620	COG2205	protein histidine kinase activity
FKQ53_RS12620	COG0784	Response regulator, receiver
FKQ53_RS12625	COG2197	response regulator
FKQ53_RS12640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ53_RS12645	COG0598	Magnesium transport protein CorA
FKQ53_RS12650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FKQ53_RS12650	COG1042	CoA-binding domain protein
FKQ53_RS12650	COG0045	succinate-CoA ligase (ADP-forming) activity
FKQ53_RS12655	COG0783	Belongs to the Dps family
FKQ53_RS12685	COG3138	arginine N-succinyltransferase
FKQ53_RS12700	COG0765	amino acid transport
FKQ53_RS12710	COG0028	Belongs to the TPP enzyme family
FKQ53_RS12715	COG1522	sequence-specific DNA binding
FKQ53_RS12725	COG1272	protein, Hemolysin III
FKQ53_RS12730	COG0784	Response regulator, receiver
FKQ53_RS12730	COG2205	protein histidine kinase activity
FKQ53_RS12735	COG0840	transmembrane signaling receptor activity
FKQ53_RS12740	COG1254	Belongs to the acylphosphatase family
FKQ53_RS12755	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FKQ53_RS12760	COG1024	Enoyl-CoA hydratase
FKQ53_RS12770	COG0084	hydrolase, TatD family'
FKQ53_RS12780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FKQ53_RS12785	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FKQ53_RS12790	COG0354	folic acid binding
FKQ53_RS12805	COG2130	NADP-dependent
FKQ53_RS12815	COG1335	isochorismatase
FKQ53_RS12830	COG0411	ABC transporter
FKQ53_RS12845	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ53_RS12850	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FKQ53_RS12855	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FKQ53_RS12865	COG2917	probably involved in intracellular septation
FKQ53_RS12875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FKQ53_RS12880	COG0047	phosphoribosylformylglycinamidine synthase activity
FKQ53_RS12880	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FKQ53_RS12885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FKQ53_RS12890	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FKQ53_RS12890	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FKQ53_RS12900	COG4181	ATPase activity
FKQ53_RS12910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FKQ53_RS12930	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FKQ53_RS12940	COG0740	serine-type endopeptidase activity
FKQ53_RS12945	COG0544	peptidyl-prolyl cis-trans isomerase activity
FKQ53_RS12955	COG1960	acyl-CoA dehydrogenase activity
FKQ53_RS12975	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ53_RS12985	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FKQ53_RS12995	COG0850	regulation of cytokinetic process
FKQ53_RS13005	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS13010	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS13015	COG0583	DNA-binding transcription factor activity
FKQ53_RS13020	COG2974	May be involved in recombination
FKQ53_RS13030	COG1132	(ABC) transporter
FKQ53_RS13035	COG0189	ligase activity
FKQ53_RS13035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FKQ53_RS13040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FKQ53_RS13040	COG1181	Belongs to the D-alanine--D-alanine ligase family
FKQ53_RS13060	COG0583	DNA-binding transcription factor activity
FKQ53_RS13065	COG0657	acetylesterase activity
FKQ53_RS13070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKQ53_RS13090	COG0617	tRNA 3'-terminal CCA addition
FKQ53_RS13090	COG3620	sequence-specific DNA binding
FKQ53_RS13090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FKQ53_RS13105	COG0024	Methionine aminopeptidase
FKQ53_RS13155	COG2860	membrane
FKQ53_RS13160	COG2272	Belongs to the type-B carboxylesterase lipase family
FKQ53_RS13165	COG3012	SEC-C Motif Domain Protein
FKQ53_RS13235	COG1338	Plays a role in the flagellum-specific transport system
FKQ53_RS13245	COG1776	CheC inhibitor of MCP methylation
FKQ53_RS13245	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FKQ53_RS13260	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FKQ53_RS13275	COG1157	protein secretion by the type III secretion system
FKQ53_RS13295	COG1677	Flagellar hook-basal body complex protein FliE
FKQ53_RS13300	COG1558	bacterial-type flagellum-dependent cell motility
FKQ53_RS13310	COG1706	bacterial-type flagellum-dependent cell motility
FKQ53_RS13315	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FKQ53_RS13325	COG4786	Flagellar basal body rod
FKQ53_RS13335	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FKQ53_RS13340	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FKQ53_RS13350	COG1987	bacterial-type flagellum assembly
FKQ53_RS13400	COG2826	transposase and inactivated derivatives, IS30 family
FKQ53_RS13415	COG0582	viral genome integration into host DNA
FKQ53_RS13455	COG0450	alkyl hydroperoxide reductase
FKQ53_RS13460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FKQ53_RS13465	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FKQ53_RS13470	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FKQ53_RS13475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FKQ53_RS13505	COG4977	sequence-specific DNA binding
FKQ53_RS13515	COG0560	Phosphoserine phosphatase
FKQ53_RS13530	COG0626	cystathionine gamma-synthase activity
FKQ53_RS13535	COG0183	Belongs to the thiolase family
FKQ53_RS13540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKQ53_RS13545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FKQ53_RS13555	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS13560	COG0183	Belongs to the thiolase family
FKQ53_RS13565	COG3243	poly(R)-hydroxyalkanoic acid synthase
FKQ53_RS13580	COG0564	pseudouridine synthase activity
FKQ53_RS13590	COG1199	ATP-dependent helicase activity
FKQ53_RS13605	COG2183	response to ionizing radiation
FKQ53_RS13610	COG3158	transport of potassium into the cell
FKQ53_RS13655	COG4964	Belongs to the GSP D family
FKQ53_RS13700	COG1846	Transcriptional regulator
FKQ53_RS13735	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FKQ53_RS13740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKQ53_RS13745	COG0508	dehydrogenase complex catalyzes the overall conversion of
FKQ53_RS13750	COG0567	Dehydrogenase, E1 component
FKQ53_RS13755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FKQ53_RS13760	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FKQ53_RS13770	COG0840	transmembrane signaling receptor activity
FKQ53_RS13780	COG1280	lysine exporter protein (LysE YggA)
FKQ53_RS13810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FKQ53_RS13820	COG1278	Cold shock
FKQ53_RS13840	COG2207	Transcriptional regulator
FKQ53_RS13845	COG0300	oxidoreductase activity
FKQ53_RS13875	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FKQ53_RS13915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FKQ53_RS13930	COG1177	transmembrane transport
FKQ53_RS13935	COG1176	ABC-type spermidine putrescine transport system, permease component I
FKQ53_RS13940	COG3842	ATPase activity
FKQ53_RS13965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FKQ53_RS13970	COG3706	GGDEF domain
FKQ53_RS13980	COG2501	S4 domain
FKQ53_RS13985	COG2202	Pas domain
FKQ53_RS13985	COG2200	EAL domain
FKQ53_RS13985	COG2199	diguanylate cyclase activity
FKQ53_RS14010	COG1773	rubredoxin
FKQ53_RS14020	COG3706	GGDEF domain
FKQ53_RS14025	COG3300	MHYT domain
FKQ53_RS14025	COG5001	Diguanylate cyclase
FKQ53_RS14035	COG0776	regulation of translation
FKQ53_RS14050	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FKQ53_RS14060	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FKQ53_RS14065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FKQ53_RS14075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FKQ53_RS14080	COG0251	oxidation-reduction process
FKQ53_RS14090	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS14105	COG2197	response regulator
FKQ53_RS14115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FKQ53_RS14120	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS14140	COG0477	Major facilitator Superfamily
FKQ53_RS14155	COG2267	carboxylic ester hydrolase activity
FKQ53_RS14165	COG1295	ribonuclease BN
FKQ53_RS14180	COG0277	FAD linked oxidase domain protein
FKQ53_RS14205	COG0534	Mate efflux family protein
FKQ53_RS14240	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FKQ53_RS14255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FKQ53_RS14260	COG1652	LysM domain
FKQ53_RS14265	COG1183	phosphatidylcholine synthase activity
FKQ53_RS14270	COG0688	phosphatidylethanolamine metabolic process
FKQ53_RS14275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FKQ53_RS14285	COG0028	Belongs to the TPP enzyme family
FKQ53_RS14290	COG1595	DNA-templated transcription, initiation
FKQ53_RS14330	COG1309	transcriptional regulator
FKQ53_RS14350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FKQ53_RS14365	COG0840	transmembrane signaling receptor activity
FKQ53_RS14370	COG2824	Alkylphosphonate utilization operon protein PhnA
FKQ53_RS14375	COG0659	secondary active sulfate transmembrane transporter activity
FKQ53_RS14385	COG2271	Major facilitator Superfamily
FKQ53_RS14390	COG2346	COG2346, Truncated hemoglobins
FKQ53_RS14395	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FKQ53_RS14410	COG0745	RESPONSE REGULATOR receiver
FKQ53_RS14415	COG2205	protein histidine kinase activity
FKQ53_RS14425	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FKQ53_RS14430	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FKQ53_RS14445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKQ53_RS14470	COG1741	Belongs to the pirin family
FKQ53_RS14480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FKQ53_RS14495	COG1561	YicC-like family, N-terminal region
FKQ53_RS14505	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FKQ53_RS14510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FKQ53_RS14515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FKQ53_RS14525	COG0583	DNA-binding transcription factor activity
FKQ53_RS14530	COG1942	4-Oxalocrotonate Tautomerase
FKQ53_RS14545	COG0583	DNA-binding transcription factor activity
FKQ53_RS14555	COG1522	sequence-specific DNA binding
FKQ53_RS14565	COG0242	peptide deformylase activity
FKQ53_RS14570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FKQ53_RS14575	COG0156	8-amino-7-oxononanoate synthase activity
FKQ53_RS14605	COG4106	trans-aconitate 2-methyltransferase activity
FKQ53_RS14625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FKQ53_RS14635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FKQ53_RS14640	COG2271	Major facilitator Superfamily
FKQ53_RS14700	COG0411	ABC transporter
FKQ53_RS14740	COG1176	ABC-type spermidine putrescine transport system, permease component I
FKQ53_RS14745	COG3842	ATPase activity
FKQ53_RS14755	COG0583	DNA-binding transcription factor activity
FKQ53_RS14780	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FKQ53_RS14800	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FKQ53_RS14815	COG2223	nitrite transmembrane transporter activity
FKQ53_RS14825	COG1271	oxidase subunit
FKQ53_RS14830	COG1294	oxidase, subunit
FKQ53_RS14845	COG0302	gtp cyclohydrolase
FKQ53_RS14855	COG1131	(ABC) transporter
FKQ53_RS14860	COG0842	Transport permease protein
FKQ53_RS14870	COG0583	DNA-binding transcription factor activity
FKQ53_RS14885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FKQ53_RS14905	COG1929	Belongs to the glycerate kinase type-1 family
FKQ53_RS14950	COG0583	DNA-binding transcription factor activity
FKQ53_RS14955	COG2271	Major facilitator Superfamily
FKQ53_RS14965	COG0129	dihydroxy-acid dehydratase activity
FKQ53_RS14975	COG0747	negative chemotaxis
FKQ53_RS14995	COG2814	Major facilitator Superfamily
FKQ53_RS15000	COG2814	Major facilitator Superfamily
FKQ53_RS15010	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FKQ53_RS15020	COG0583	DNA-binding transcription factor activity
FKQ53_RS15025	COG0427	acetyl-CoA hydrolase
FKQ53_RS15045	COG0252	asparaginase activity
FKQ53_RS15060	COG3046	protein related to deoxyribodipyrimidine photolyase
FKQ53_RS15080	COG0583	DNA-binding transcription factor activity
FKQ53_RS15085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FKQ53_RS15090	COG3002	Belongs to the UPF0753 family
FKQ53_RS15095	COG1012	belongs to the aldehyde dehydrogenase family
FKQ53_RS15105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FKQ53_RS15110	COG1012	belongs to the aldehyde dehydrogenase family
FKQ53_RS15115	COG1522	sequence-specific DNA binding
FKQ53_RS15120	COG3608	succinylglutamate desuccinylase aspartoacylase
FKQ53_RS15125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FKQ53_RS15135	COG3835	regulator
FKQ53_RS15145	COG1012	belongs to the aldehyde dehydrogenase family
FKQ53_RS15150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FKQ53_RS15165	COG4175	Glycine betaine
FKQ53_RS15170	COG4176	ABC-type proline glycine betaine transport system permease component
FKQ53_RS15175	COG2113	Glycine betaine
FKQ53_RS15190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FKQ53_RS15205	COG1610	YqeY-like protein
FKQ53_RS15210	COG2081	HI0933 family
FKQ53_RS15220	COG0671	phosphoesterase, PA-phosphatase related
FKQ53_RS15230	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FKQ53_RS15235	COG1469	GTP cyclohydrolase I activity
FKQ53_RS15240	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FKQ53_RS15245	COG0142	geranyltranstransferase activity
FKQ53_RS15250	COG1722	exodeoxyribonuclease VII activity
FKQ53_RS15275	COG0412	Dienelactone hydrolase
FKQ53_RS15280	COG1252	NADH dehydrogenase
FKQ53_RS15290	COG1611	Belongs to the LOG family
FKQ53_RS15295	COG2391	methyltransferase activity
FKQ53_RS15305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FKQ53_RS15315	COG0210	DNA helicase
FKQ53_RS15320	COG0525	valine-tRNA ligase activity
FKQ53_RS15330	COG0425	Belongs to the sulfur carrier protein TusA family
FKQ53_RS15350	COG1942	4-Oxalocrotonate Tautomerase
FKQ53_RS15355	COG0235	Class ii aldolase
FKQ53_RS15360	COG0477	Major facilitator Superfamily
FKQ53_RS15365	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FKQ53_RS15370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ53_RS15385	COG1335	isochorismatase
FKQ53_RS15400	COG0066	3-isopropylmalate dehydratase activity
FKQ53_RS15405	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FKQ53_RS15435	COG2188	Transcriptional regulator
FKQ53_RS15465	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FKQ53_RS15475	COG0668	transmembrane transport
FKQ53_RS15500	COG1021	2,3-dihydroxybenzoate-AMP ligase
FKQ53_RS15525	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FKQ53_RS15540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKQ53_RS15550	COG0625	glutathione transferase activity
FKQ53_RS15570	COG2186	Transcriptional regulator
FKQ53_RS15645	COG2062	phosphohistidine phosphatase, SixA
FKQ53_RS15655	COG0248	Ppx GppA phosphatase
FKQ53_RS15660	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FKQ53_RS15670	COG0745	RESPONSE REGULATOR receiver
FKQ53_RS15680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FKQ53_RS15685	COG0581	inorganic phosphate transmembrane transporter activity
FKQ53_RS15690	COG0573	inorganic phosphate transmembrane transporter activity
FKQ53_RS15695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FKQ53_RS15710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FKQ53_RS15720	COG1534	Rna-binding protein
FKQ53_RS15730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FKQ53_RS15735	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FKQ53_RS15745	COG0505	Belongs to the CarA family
FKQ53_RS15765	COG1301	dicarboxylic acid transport
FKQ53_RS15770	COG4266	Belongs to the allantoicase family
FKQ53_RS15780	COG2259	Doxx family
FKQ53_RS15805	COG1024	Enoyl-CoA hydratase
FKQ53_RS15810	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS15820	COG0477	Major facilitator Superfamily
FKQ53_RS15830	COG0583	DNA-binding transcription factor activity
FKQ53_RS15835	COG2814	Major facilitator Superfamily
FKQ53_RS15845	COG0741	lytic transglycosylase activity
FKQ53_RS15845	COG1388	LysM domain
FKQ53_RS15850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FKQ53_RS15860	COG0328	RNA-DNA hybrid ribonuclease activity
FKQ53_RS15865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FKQ53_RS15890	COG2271	Major facilitator Superfamily
FKQ53_RS15900	COG2814	Major facilitator Superfamily
FKQ53_RS15920	COG2252	PERMEase
FKQ53_RS15945	COG2902	Dehydrogenase
FKQ53_RS15950	COG0513	Belongs to the DEAD box helicase family
FKQ53_RS15965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FKQ53_RS15990	COG2233	PERMEase
FKQ53_RS15995	COG0587	DNA-directed DNA polymerase activity
FKQ53_RS16010	COG1914	H( )-stimulated, divalent metal cation uptake system
FKQ53_RS16035	COG0789	Transcriptional regulator
FKQ53_RS16040	COG3568	Endonuclease Exonuclease Phosphatase
FKQ53_RS16045	COG2217	Heavy metal translocating P-type atpase
FKQ53_RS16050	COG2608	mercury ion transmembrane transporter activity
FKQ53_RS16065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FKQ53_RS16065	COG4651	solute:proton antiporter activity
FKQ53_RS16085	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FKQ53_RS16095	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FKQ53_RS16100	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FKQ53_RS16110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FKQ53_RS16115	COG2252	PERMEase
FKQ53_RS16120	COG0402	S-adenosylhomocysteine deaminase activity
FKQ53_RS16125	COG2119	membrane
FKQ53_RS16135	COG0308	aminopeptidase N
FKQ53_RS16150	COG0583	DNA-binding transcription factor activity
FKQ53_RS16155	COG0500	methyltransferase
FKQ53_RS16160	COG2814	Major facilitator Superfamily
FKQ53_RS16165	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FKQ53_RS16175	COG0540	Belongs to the ATCase OTCase family
FKQ53_RS16210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FKQ53_RS16215	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FKQ53_RS16225	COG1175	transmembrane transport
FKQ53_RS16235	COG1609	Transcriptional regulator
FKQ53_RS16255	COG1917	Cupin 2, conserved barrel domain protein
FKQ53_RS16300	COG0583	DNA-binding transcription factor activity
FKQ53_RS16305	COG1309	transcriptional regulator
FKQ53_RS16320	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FKQ53_RS16330	COG1012	belongs to the aldehyde dehydrogenase family
FKQ53_RS16345	COG0583	DNA-binding transcription factor activity
FKQ53_RS16350	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS16355	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FKQ53_RS16370	COG1683	Conserved Protein
FKQ53_RS16375	COG0693	protein deglycase activity
FKQ53_RS16395	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FKQ53_RS16425	COG1305	Transglutaminase-like
FKQ53_RS16430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FKQ53_RS16435	COG0583	DNA-binding transcription factor activity
FKQ53_RS16480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FKQ53_RS16485	COG1280	lysine exporter protein (LysE YggA)
FKQ53_RS16490	COG1522	sequence-specific DNA binding
FKQ53_RS16500	COG0583	DNA-binding transcription factor activity
FKQ53_RS16515	COG1742	UPF0060 membrane protein
FKQ53_RS16520	COG2900	Belongs to the SlyX family
FKQ53_RS16530	COG1764	response to oxidative stress
FKQ53_RS16545	COG1522	sequence-specific DNA binding
FKQ53_RS16555	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS16560	COG0583	DNA-binding transcription factor activity
FKQ53_RS16580	COG1131	(ABC) transporter
FKQ53_RS16585	COG0842	Transport permease protein
FKQ53_RS16645	COG2207	Transcriptional regulator
FKQ53_RS16670	COG0277	FAD linked oxidase domain protein
FKQ53_RS16670	COG0247	lactate metabolic process
FKQ53_RS16675	COG2271	Major facilitator Superfamily
FKQ53_RS16680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FKQ53_RS16685	COG1802	Transcriptional regulator
FKQ53_RS16690	COG0655	NAD(P)H dehydrogenase (quinone) activity
FKQ53_RS16695	COG1414	Transcriptional regulator
FKQ53_RS16730	COG1454	alcohol dehydrogenase
FKQ53_RS16740	COG2197	response regulator
FKQ53_RS16745	COG3916	Acyl-homoserine-lactone synthase
FKQ53_RS16765	COG2897	thiosulfate sulfurtransferase activity
FKQ53_RS16785	COG0154	amidase activity
FKQ53_RS16800	COG0583	DNA-binding transcription factor activity
FKQ53_RS16810	COG1304	FMN binding
FKQ53_RS16815	COG1522	sequence-specific DNA binding
FKQ53_RS16820	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS16825	COG1309	transcriptional regulator
FKQ53_RS16855	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ53_RS16860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FKQ53_RS16865	COG2982	Protein involved in outer membrane biogenesis
FKQ53_RS16870	COG0259	pyridoxamine-phosphate oxidase activity
FKQ53_RS16875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FKQ53_RS16885	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FKQ53_RS16890	COG0477	Major facilitator Superfamily
FKQ53_RS16905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FKQ53_RS16910	COG0010	Belongs to the arginase family
FKQ53_RS16915	COG1126	abc transporter atp-binding protein
FKQ53_RS16920	COG0765	amino acid transport
FKQ53_RS16925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKQ53_RS16945	COG2267	carboxylic ester hydrolase activity
FKQ53_RS16950	COG2309	aminopeptidase activity
FKQ53_RS16955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FKQ53_RS16965	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FKQ53_RS16975	COG3483	tryptophan 2,3-dioxygenase activity
FKQ53_RS16985	COG1960	acyl-CoA dehydrogenase activity
FKQ53_RS16990	COG0450	alkyl hydroperoxide reductase
FKQ53_RS16995	COG4575	ribosome binding
FKQ53_RS17010	COG4970	Tfp pilus assembly protein FimT
FKQ53_RS17050	COG1309	transcriptional regulator
FKQ53_RS17055	COG0725	ABC transporter, periplasmic molybdate-binding protein
FKQ53_RS17060	COG4149	molybdate abc transporter
FKQ53_RS17065	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FKQ53_RS17075	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FKQ53_RS17080	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
FKQ53_RS17095	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FKQ53_RS17115	COG5295	Hep Hag repeat protein
FKQ53_RS17125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FKQ53_RS17145	COG2027	D-alanyl-D-alanine carboxypeptidase
FKQ53_RS17155	COG0009	L-threonylcarbamoyladenylate synthase
FKQ53_RS17160	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FKQ53_RS17165	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FKQ53_RS17170	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FKQ53_RS17185	COG0469	pyruvate kinase activity
FKQ53_RS17190	COG0126	phosphoglycerate kinase activity
FKQ53_RS17220	COG0429	hydrolase of the alpha beta-hydrolase fold
FKQ53_RS17235	COG0315	cyclic pyranopterin monophosphate synthase activity
FKQ53_RS17240	COG0697	spore germination
FKQ53_RS17245	COG1846	Transcriptional regulator
FKQ53_RS17250	COG2223	nitrite transmembrane transporter activity
FKQ53_RS17255	COG0583	DNA-binding transcription factor activity
FKQ53_RS17260	COG0459	protein refolding
FKQ53_RS17265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FKQ53_RS17270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS17295	COG0179	Fumarylacetoacetate (FAA) hydrolase
FKQ53_RS17300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKQ53_RS17310	COG1064	alcohol dehydrogenase
FKQ53_RS17350	COG0471	metal ion transport
FKQ53_RS17360	COG5002	protein histidine kinase activity
FKQ53_RS17365	COG0745	RESPONSE REGULATOR receiver
FKQ53_RS17370	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FKQ53_RS17380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FKQ53_RS17390	COG2378	regulation of single-species biofilm formation
FKQ53_RS17395	COG2010	Cytochrome c
FKQ53_RS17430	COG1802	Transcriptional regulator
FKQ53_RS17440	COG3706	GGDEF domain
FKQ53_RS17465	COG2072	flavoprotein involved in K transport
FKQ53_RS17470	COG0601	transmembrane transport
FKQ53_RS17480	COG0444	Belongs to the ABC transporter superfamily
FKQ53_RS17485	COG4608	Belongs to the ABC transporter superfamily
FKQ53_RS17490	COG0747	negative chemotaxis
FKQ53_RS17535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FKQ53_RS17540	COG1988	membrane-bound metal-dependent
FKQ53_RS17560	COG0673	inositol 2-dehydrogenase activity
FKQ53_RS17570	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FKQ53_RS17575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FKQ53_RS17580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKQ53_RS17585	COG1309	transcriptional regulator
FKQ53_RS17595	COG2226	methyltransferase
FKQ53_RS17625	COG1116	anion transmembrane transporter activity
FKQ53_RS17625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FKQ53_RS17640	COG0243	molybdopterin cofactor binding
FKQ53_RS17650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FKQ53_RS17655	COG1960	acyl-CoA dehydrogenase activity
FKQ53_RS17660	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ53_RS17670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FKQ53_RS17675	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS17680	COG1846	Transcriptional regulator
FKQ53_RS17715	COG2197	response regulator
FKQ53_RS17740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKQ53_RS17760	COG0477	Major facilitator Superfamily
FKQ53_RS17775	COG1802	Transcriptional regulator
FKQ53_RS17790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FKQ53_RS17795	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FKQ53_RS17800	COG0582	viral genome integration into host DNA
FKQ53_RS17820	COG1309	transcriptional regulator
FKQ53_RS17825	COG1024	Enoyl-CoA hydratase
FKQ53_RS17830	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ53_RS17835	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FKQ53_RS17840	COG1024	Enoyl-CoA hydratase
FKQ53_RS17850	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FKQ53_RS17900	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS17920	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FKQ53_RS18015	COG0210	DNA helicase
FKQ53_RS18085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FKQ53_RS18095	COG0436	Aminotransferase
FKQ53_RS18120	COG0183	Belongs to the thiolase family
FKQ53_RS18125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FKQ53_RS18135	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS18140	COG0583	DNA-binding transcription factor activity
FKQ53_RS18145	COG3284	Transcriptional regulator
FKQ53_RS18150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS18155	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FKQ53_RS18170	COG1803	Methylglyoxal synthase
FKQ53_RS18175	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS18180	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FKQ53_RS18190	COG0433	COG0433 Predicted ATPase
FKQ53_RS18195	COG0217	transcriptional regulatory protein
FKQ53_RS18200	COG0151	Belongs to the GarS family
FKQ53_RS18205	COG0668	transmembrane transport
FKQ53_RS18210	COG0408	coproporphyrinogen oxidase activity
FKQ53_RS18220	COG0799	negative regulation of ribosome biogenesis
FKQ53_RS18225	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FKQ53_RS18230	COG1653	transport
FKQ53_RS18235	COG1175	transmembrane transport
FKQ53_RS18240	COG0395	ABC-type sugar transport system, permease component
FKQ53_RS18250	COG0584	glycerophosphoryl diester phosphodiesterase
FKQ53_RS18255	COG0424	maF-like protein
FKQ53_RS18260	COG1530	ribonuclease E activity
FKQ53_RS18265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FKQ53_RS18315	COG1054	Belongs to the UPF0176 family
FKQ53_RS18320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKQ53_RS18325	COG0513	Belongs to the DEAD box helicase family
FKQ53_RS18335	COG0583	DNA-binding transcription factor activity
FKQ53_RS18345	COG0655	NAD(P)H dehydrogenase (quinone) activity
FKQ53_RS18360	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FKQ53_RS18365	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FKQ53_RS18375	COG1253	flavin adenine dinucleotide binding
FKQ53_RS18380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FKQ53_RS18385	COG1074	ATP-dependent DNA helicase activity
FKQ53_RS18390	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FKQ53_RS18395	COG1289	transmembrane transporter activity
FKQ53_RS18400	COG2197	response regulator
FKQ53_RS18410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKQ53_RS18415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKQ53_RS18435	COG2916	Histone family protein nucleoid-structuring protein H-NS
FKQ53_RS18445	COG0477	Major facilitator Superfamily
FKQ53_RS18460	COG0640	Transcriptional regulator
FKQ53_RS18470	COG0583	DNA-binding transcription factor activity
FKQ53_RS18485	COG0280	phosphate acetyltransferase
FKQ53_RS18485	COG0281	malic enzyme
FKQ53_RS18505	COG0346	lactoylglutathione lyase activity
FKQ53_RS18545	COG0543	2 iron, 2 sulfur cluster binding
FKQ53_RS18545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FKQ53_RS18550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FKQ53_RS18570	COG0411	ABC transporter
FKQ53_RS18590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FKQ53_RS18595	COG1047	Peptidyl-prolyl cis-trans
FKQ53_RS18600	COG2003	Belongs to the UPF0758 family
FKQ53_RS18610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FKQ53_RS18615	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FKQ53_RS18625	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FKQ53_RS18635	COG3264	Mechanosensitive ion channel
FKQ53_RS18635	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FKQ53_RS18640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FKQ53_RS18640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FKQ53_RS18645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FKQ53_RS18650	COG0196	riboflavin kinase activity
FKQ53_RS18660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FKQ53_RS18665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FKQ53_RS18670	COG2814	Major facilitator Superfamily
FKQ53_RS18675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FKQ53_RS18685	COG0542	response to heat
FKQ53_RS18690	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FKQ53_RS18695	COG1278	Cold shock
FKQ53_RS18725	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS18730	COG0583	DNA-binding transcription factor activity
FKQ53_RS18770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FKQ53_RS18775	COG1570	exodeoxyribonuclease VII activity
FKQ53_RS18780	COG0811	peptide transport
FKQ53_RS18805	COG0563	adenylate kinase activity
FKQ53_RS18820	COG2912	Transglutaminase-like superfamily
FKQ53_RS18825	COG0728	peptidoglycan biosynthetic process
FKQ53_RS18830	COG0268	Binds directly to 16S ribosomal RNA
FKQ53_RS18840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FKQ53_RS18845	COG3123	guanosine phosphorylase activity
FKQ53_RS18855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FKQ53_RS18860	COG1666	GTP binding
FKQ53_RS18865	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FKQ53_RS18870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FKQ53_RS18875	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ53_RS18885	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FKQ53_RS18890	COG0802	atpase or kinase
FKQ53_RS18895	COG0860	N-Acetylmuramoyl-L-alanine amidase
FKQ53_RS18900	COG0586	Pfam SNARE associated Golgi protein
FKQ53_RS18905	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FKQ53_RS18910	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FKQ53_RS18930	COG1176	ABC-type spermidine putrescine transport system, permease component I
FKQ53_RS18935	COG0006	proline dipeptidase activity
FKQ53_RS18940	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FKQ53_RS18955	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FKQ53_RS18965	COG0617	tRNA 3'-terminal CCA addition
FKQ53_RS18970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FKQ53_RS18975	COG1428	Deoxynucleoside kinase
FKQ53_RS18985	COG0642	Histidine kinase
FKQ53_RS19000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKQ53_RS19020	COG0443	Heat shock 70 kDa protein
FKQ53_RS19030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FKQ53_RS19045	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FKQ53_RS19065	COG0497	DNA recombination
FKQ53_RS19070	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FKQ53_RS19080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FKQ53_RS19085	COG0312	modulator of DNA gyrase
FKQ53_RS19090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FKQ53_RS19095	COG2096	Adenosyltransferase
FKQ53_RS19100	COG0277	FAD linked oxidase domain protein
FKQ53_RS19105	COG0277	FAD linked oxidase domain protein
FKQ53_RS19110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKQ53_RS19115	COG0277	FAD linked oxidase domain protein
FKQ53_RS19120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKQ53_RS19130	COG0386	Belongs to the glutathione peroxidase family
FKQ53_RS19145	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FKQ53_RS19155	COG0672	)-iron permease
FKQ53_RS19160	COG4633	Protein conserved in bacteria
FKQ53_RS19175	COG0765	amino acid transport
FKQ53_RS19180	COG0765	amino acid transport
FKQ53_RS19185	COG1126	abc transporter atp-binding protein
FKQ53_RS19205	COG0662	Cupin 2, conserved barrel domain protein
FKQ53_RS19210	COG0667	Aldo Keto reductase
FKQ53_RS19215	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS19220	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS19230	COG1741	Belongs to the pirin family
FKQ53_RS19235	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS19240	COG0583	DNA-binding transcription factor activity
FKQ53_RS19260	COG3634	alkyl hydroperoxide reductase activity
FKQ53_RS19305	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FKQ53_RS19310	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FKQ53_RS19370	COG3842	ATPase activity
FKQ53_RS19380	COG4948	Mandelate Racemase Muconate Lactonizing
FKQ53_RS19385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS19390	COG2188	Transcriptional regulator
FKQ53_RS19395	COG0583	DNA-binding transcription factor activity
FKQ53_RS19405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FKQ53_RS19410	COG0583	DNA-binding transcription factor activity
FKQ53_RS19435	COG3328	transposase activity
FKQ53_RS19465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FKQ53_RS19470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FKQ53_RS19475	COG0322	excinuclease ABC activity
FKQ53_RS19495	COG0736	holo-[acyl-carrier-protein] synthase activity
FKQ53_RS19500	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FKQ53_RS19510	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FKQ53_RS19515	COG0571	ribonuclease III activity
FKQ53_RS19520	COG0681	Belongs to the peptidase S26 family
FKQ53_RS19535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FKQ53_RS19555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FKQ53_RS19560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FKQ53_RS19565	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS19580	COG0416	fatty acid biosynthetic process
FKQ53_RS19585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FKQ53_RS19590	COG1399	metal-binding, possibly nucleic acid-binding protein
FKQ53_RS19600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FKQ53_RS19605	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FKQ53_RS19605	COG0616	signal peptide processing
FKQ53_RS19615	COG0546	phosphoglycolate phosphatase activity
FKQ53_RS19620	COG0564	pseudouridine synthase activity
FKQ53_RS19625	COG1530	ribonuclease E activity
FKQ53_RS19630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FKQ53_RS19640	COG0746	molybdenum cofactor guanylyltransferase activity
FKQ53_RS19645	COG0303	'Molybdopterin
FKQ53_RS19675	COG1556	Lactate utilization protein
FKQ53_RS19680	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FKQ53_RS19685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FKQ53_RS19710	COG0277	FAD linked oxidase domain protein
FKQ53_RS19715	COG0277	FAD linked oxidase domain protein
FKQ53_RS19720	COG0247	lactate metabolic process
FKQ53_RS19730	COG3384	dioxygenase
FKQ53_RS19735	COG0583	DNA-binding transcription factor activity
FKQ53_RS19740	COG1253	flavin adenine dinucleotide binding
FKQ53_RS19745	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FKQ53_RS19750	COG1280	lysine exporter protein (LysE YggA)
FKQ53_RS19755	COG1278	Cold shock
FKQ53_RS19760	COG4942	peptidase
FKQ53_RS19765	COG2943	transferase activity, transferring hexosyl groups
FKQ53_RS19770	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FKQ53_RS19775	COG1280	lysine exporter protein (LysE YggA)
FKQ53_RS19785	COG0534	Mate efflux family protein
FKQ53_RS19795	COG2807	transmembrane transport
FKQ53_RS19805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FKQ53_RS19820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FKQ53_RS19825	COG2205	protein histidine kinase activity
FKQ53_RS19825	COG0745	RESPONSE REGULATOR receiver
FKQ53_RS19825	COG3292	Two component regulator propeller
FKQ53_RS19830	COG2198	Histidine kinase
FKQ53_RS19830	COG0784	Response regulator, receiver
FKQ53_RS19830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKQ53_RS19830	COG2205	protein histidine kinase activity
FKQ53_RS19845	COG0583	DNA-binding transcription factor activity
FKQ53_RS19870	COG2855	membrane
FKQ53_RS19885	COG2885	chlorophyll binding
FKQ53_RS19915	COG0531	amino acid
FKQ53_RS19940	COG2031	fatty acid transporter
FKQ53_RS19965	COG3781	membrane
FKQ53_RS20000	COG2814	Major facilitator Superfamily
FKQ53_RS20005	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FKQ53_RS20025	COG2249	NAD(P)H dehydrogenase (quinone) activity
FKQ53_RS20035	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FKQ53_RS20050	COG0625	glutathione transferase activity
FKQ53_RS20055	COG0405	Gamma-glutamyltransferase
FKQ53_RS20095	COG2814	Major facilitator Superfamily
FKQ53_RS20120	COG2814	Major facilitator Superfamily
FKQ53_RS20130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FKQ53_RS20135	COG1968	undecaprenyl-diphosphatase activity
FKQ53_RS20160	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FKQ53_RS20195	COG0438	transferase activity, transferring glycosyl groups
FKQ53_RS20200	COG0438	transferase activity, transferring glycosyl groups
FKQ53_RS20210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FKQ53_RS20215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FKQ53_RS20220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FKQ53_RS20235	COG0540	Belongs to the ATCase OTCase family
FKQ53_RS20240	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FKQ53_RS20245	COG1678	Uncharacterized ACR, COG1678
FKQ53_RS20255	COG1773	rubredoxin
FKQ53_RS20260	COG0351	phosphomethylpyrimidine kinase
FKQ53_RS20270	COG4969	Belongs to the N-Me-Phe pilin family
FKQ53_RS20275	COG0861	Integral membrane protein TerC family
FKQ53_RS20280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FKQ53_RS20285	COG0045	succinate-CoA ligase (ADP-forming) activity
FKQ53_RS20295	COG2137	regulation of response to DNA damage stimulus
FKQ53_RS20300	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FKQ53_RS20310	COG0642	Histidine kinase
FKQ53_RS20315	COG0477	Major facilitator Superfamily
FKQ53_RS20330	COG1253	flavin adenine dinucleotide binding
FKQ53_RS20335	COG0583	DNA-binding transcription factor activity
FKQ53_RS20340	COG0628	permease
FKQ53_RS20355	COG1116	anion transmembrane transporter activity
FKQ53_RS20365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FKQ53_RS20370	COG0156	8-amino-7-oxononanoate synthase activity
FKQ53_RS20375	COG1396	sequence-specific DNA binding
FKQ53_RS20380	COG0840	transmembrane signaling receptor activity
FKQ53_RS20395	COG1902	pentaerythritol trinitrate reductase activity
FKQ53_RS20400	COG0668	transmembrane transport
FKQ53_RS20425	COG3706	GGDEF domain
FKQ53_RS20435	COG2719	SpoVR family
FKQ53_RS20440	COG2718	Belongs to the UPF0229 family
FKQ53_RS20445	COG2766	serine protein kinase
FKQ53_RS20450	COG1121	(ABC) transporter
FKQ53_RS20460	COG0803	Belongs to the bacterial solute-binding protein 9 family
FKQ53_RS20465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FKQ53_RS20470	COG1702	phosphate starvation-inducible protein PhoH
FKQ53_RS20475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FKQ53_RS20480	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FKQ53_RS20490	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FKQ53_RS20495	COG0752	glycyl-tRNA synthetase alpha subunit
FKQ53_RS20500	COG0751	glycine-tRNA ligase activity
FKQ53_RS20505	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FKQ53_RS20510	COG0204	Acyl-transferase
FKQ53_RS20520	COG0346	lactoylglutathione lyase activity
FKQ53_RS20525	COG1773	rubredoxin
FKQ53_RS20535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FKQ53_RS20540	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FKQ53_RS20545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FKQ53_RS20550	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FKQ53_RS20565	COG0006	proline dipeptidase activity
FKQ53_RS20570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKQ53_RS20580	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FKQ53_RS20585	COG0138	bifunctional purine biosynthesis protein purh
FKQ53_RS20590	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS20595	COG3608	succinylglutamate desuccinylase aspartoacylase
FKQ53_RS20595	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FKQ53_RS20610	COG1917	Cupin 2, conserved barrel domain protein
FKQ53_RS20610	COG4977	sequence-specific DNA binding
FKQ53_RS20620	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FKQ53_RS20635	COG0495	leucyl-tRNA aminoacylation
FKQ53_RS20640	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FKQ53_RS20645	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FKQ53_RS20650	COG0735	belongs to the Fur family
FKQ53_RS20660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FKQ53_RS20665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FKQ53_RS20670	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FKQ53_RS20680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FKQ53_RS20695	COG4290	ribonuclease
FKQ53_RS20700	COG0280	phosphate acetyltransferase
FKQ53_RS20700	COG0281	malic enzyme
FKQ53_RS20710	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FKQ53_RS20715	COG1058	Belongs to the CinA family
FKQ53_RS20715	COG1546	Belongs to the CinA family
FKQ53_RS20720	COG0284	orotidine-5'-phosphate decarboxylase activity
FKQ53_RS20730	COG0668	transmembrane transport
FKQ53_RS20740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FKQ53_RS20745	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FKQ53_RS20760	COG0557	exoribonuclease II activity
FKQ53_RS20765	COG3150	esterase
FKQ53_RS20770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FKQ53_RS20780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FKQ53_RS20785	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FKQ53_RS20790	COG0511	ligase activity, forming carbon-carbon bonds
FKQ53_RS20795	COG0439	Biotin carboxylase
FKQ53_RS20815	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FKQ53_RS20815	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FKQ53_RS20835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FKQ53_RS20865	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FKQ53_RS20870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FKQ53_RS20875	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FKQ53_RS20880	COG2095	MarC family integral membrane protein
FKQ53_RS20915	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FKQ53_RS20920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FKQ53_RS20925	COG0142	geranyltranstransferase activity
FKQ53_RS20940	COG0753	catalase activity
FKQ53_RS20955	COG4536	flavin adenine dinucleotide binding
FKQ53_RS20980	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FKQ53_RS20985	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FKQ53_RS20990	COG0494	nUDIX hydrolase
FKQ53_RS21000	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FKQ53_RS21005	COG0653	protein targeting
FKQ53_RS21015	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FKQ53_RS21030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FKQ53_RS21035	COG1181	Belongs to the D-alanine--D-alanine ligase family
FKQ53_RS21040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FKQ53_RS21045	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FKQ53_RS21055	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FKQ53_RS21065	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FKQ53_RS21070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FKQ53_RS21080	COG3116	cell division
FKQ53_RS21085	COG0275	rRNA processing
FKQ53_RS21100	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS21115	COG0243	molybdopterin cofactor binding
FKQ53_RS21120	COG1473	amidohydrolase
FKQ53_RS21160	COG1024	Enoyl-CoA hydratase
FKQ53_RS21170	COG0183	Belongs to the thiolase family
FKQ53_RS21175	COG1024	Enoyl-CoA hydratase
FKQ53_RS21180	COG2050	protein possibly involved in aromatic compounds catabolism
FKQ53_RS21190	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FKQ53_RS21200	COG2967	ApaG domain
FKQ53_RS21205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FKQ53_RS21210	COG0546	phosphoglycolate phosphatase activity
FKQ53_RS21225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKQ53_RS21230	COG1129	ABC transporter
FKQ53_RS21230	COG0842	Transport permease protein
FKQ53_RS21235	COG0842	Transport permease protein
FKQ53_RS21245	COG0745	RESPONSE REGULATOR receiver
FKQ53_RS21260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FKQ53_RS21265	COG0134	indole-3-glycerol-phosphate synthase activity
FKQ53_RS21275	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FKQ53_RS21290	COG0583	DNA-binding transcription factor activity
FKQ53_RS21305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKQ53_RS21310	COG2321	neutral zinc metallopeptidase
FKQ53_RS21315	COG0012	GTP binding
FKQ53_RS21335	COG0463	Glycosyl transferase, family 2
FKQ53_RS21345	COG0477	Major facilitator Superfamily
FKQ53_RS21355	COG2261	transglycosylase associated protein
FKQ53_RS21360	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FKQ53_RS21365	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FKQ53_RS21370	COG2890	protein-(glutamine-N5) methyltransferase activity
FKQ53_RS21375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FKQ53_RS21380	COG0163	prenyltransferase activity
FKQ53_RS21400	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FKQ53_RS21405	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FKQ53_RS21420	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS21425	COG0488	(ABC) transporter
FKQ53_RS21440	COG1408	metallophosphoesterase
FKQ53_RS21450	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FKQ53_RS21460	COG0517	IMP dehydrogenase activity
FKQ53_RS21465	COG0477	Major facilitator Superfamily
FKQ53_RS21505	COG0438	transferase activity, transferring glycosyl groups
FKQ53_RS21520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FKQ53_RS21525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FKQ53_RS21545	COG3045	CreA protein
FKQ53_RS21550	COG3284	Transcriptional regulator
FKQ53_RS21560	COG1454	alcohol dehydrogenase
FKQ53_RS21565	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS21570	COG1309	transcriptional regulator
FKQ53_RS21575	COG0235	Class ii aldolase
FKQ53_RS21595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FKQ53_RS21610	COG0183	Belongs to the thiolase family
FKQ53_RS21615	COG1960	acyl-CoA dehydrogenase activity
FKQ53_RS21625	COG4608	Belongs to the ABC transporter superfamily
FKQ53_RS21630	COG0444	Belongs to the ABC transporter superfamily
FKQ53_RS21635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FKQ53_RS21645	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ53_RS21655	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS21660	COG1053	succinate dehydrogenase
FKQ53_RS21665	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FKQ53_RS21670	COG0747	negative chemotaxis
FKQ53_RS21680	COG1024	Enoyl-CoA hydratase
FKQ53_RS21690	COG0439	Biotin carboxylase
FKQ53_RS21715	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKQ53_RS21720	COG1802	Transcriptional regulator
FKQ53_RS21725	COG5001	Diguanylate cyclase
FKQ53_RS21725	COG3706	GGDEF domain
FKQ53_RS21725	COG2203	Gaf domain
FKQ53_RS21725	COG4251	negative regulation of phosphorylation
FKQ53_RS21760	COG2826	transposase and inactivated derivatives, IS30 family
FKQ53_RS21780	COG3704	protein secretion by the type IV secretion system
FKQ53_RS21835	COG2969	positive regulation of protein catabolic process
FKQ53_RS21840	COG0625	glutathione transferase activity
FKQ53_RS21845	COG2857	Cytochrome c1
FKQ53_RS21850	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FKQ53_RS21855	COG0723	plastoquinol--plastocyanin reductase activity
FKQ53_RS21865	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FKQ53_RS21870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FKQ53_RS21875	COG0805	protein transport
FKQ53_RS21885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FKQ53_RS21905	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FKQ53_RS21915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FKQ53_RS21920	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FKQ53_RS21925	COG2095	MarC family integral membrane protein
FKQ53_RS21930	COG0131	Imidazoleglycerol-phosphate dehydratase
FKQ53_RS21945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FKQ53_RS21955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FKQ53_RS21965	COG0842	Transport permease protein
FKQ53_RS21970	COG1131	(ABC) transporter
FKQ53_RS21985	COG2853	Lipoprotein
FKQ53_RS21990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FKQ53_RS21995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FKQ53_RS22000	COG1127	ABC transporter
FKQ53_RS22010	COG0352	thiamine-phosphate diphosphorylase activity
FKQ53_RS22030	COG4178	(ABC) transporter
FKQ53_RS22035	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ53_RS22040	COG2814	Major facilitator Superfamily
FKQ53_RS22050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FKQ53_RS22055	COG2271	Major facilitator Superfamily
FKQ53_RS22065	COG0067	glutamate synthase
FKQ53_RS22065	COG0069	glutamate synthase activity
FKQ53_RS22065	COG0070	glutamate synthase
FKQ53_RS22075	COG3047	cAMP biosynthetic process
FKQ53_RS22090	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FKQ53_RS22095	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FKQ53_RS22125	COG1965	Belongs to the frataxin family
FKQ53_RS22135	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FKQ53_RS22140	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FKQ53_RS22145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FKQ53_RS22150	COG1333	cytochrome c biogenesis protein
FKQ53_RS22160	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FKQ53_RS22170	COG4232	protein-disulfide reductase activity
FKQ53_RS22180	COG0203	ribosomal protein L17
FKQ53_RS22185	COG0202	RNA polymerase activity
FKQ53_RS22190	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FKQ53_RS22195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FKQ53_RS22200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FKQ53_RS22205	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FKQ53_RS22210	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FKQ53_RS22215	COG0201	protein transport
FKQ53_RS22220	COG0200	Binds to the 23S rRNA
FKQ53_RS22225	COG1841	ribosomal large subunit assembly
FKQ53_RS22235	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FKQ53_RS22240	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FKQ53_RS22250	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FKQ53_RS22255	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FKQ53_RS22260	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FKQ53_RS22265	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FKQ53_RS22270	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FKQ53_RS22275	COG0255	Belongs to the universal ribosomal protein uL29 family
FKQ53_RS22285	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FKQ53_RS22290	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FKQ53_RS22295	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FKQ53_RS22300	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FKQ53_RS22305	COG0089	rRNA binding
FKQ53_RS22310	COG0088	Forms part of the polypeptide exit tunnel
FKQ53_RS22315	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FKQ53_RS22320	COG0051	transcription antitermination factor activity, RNA binding
FKQ53_RS22325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FKQ53_RS22335	COG0049	tRNA binding
FKQ53_RS22340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FKQ53_RS22345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKQ53_RS22355	COG2207	Transcriptional regulator
FKQ53_RS22385	COG0583	DNA-binding transcription factor activity
FKQ53_RS22390	COG1448	Aminotransferase
FKQ53_RS22400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FKQ53_RS22405	COG0179	Fumarylacetoacetate (FAA) hydrolase
FKQ53_RS22415	COG1012	belongs to the aldehyde dehydrogenase family
FKQ53_RS22425	COG3971	2-oxopent-4-enoate hydratase activity
FKQ53_RS22430	COG4772	TonB-dependent receptor
FKQ53_RS22435	COG5295	Hep Hag repeat protein
FKQ53_RS22450	COG0222	ribosome binding
FKQ53_RS22455	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FKQ53_RS22465	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FKQ53_RS22475	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FKQ53_RS22505	COG3012	SEC-C Motif Domain Protein
FKQ53_RS22535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKQ53_RS22545	COG3712	iron ion homeostasis
FKQ53_RS22550	COG1595	DNA-templated transcription, initiation
FKQ53_RS22570	COG0583	DNA-binding transcription factor activity
FKQ53_RS22580	COG1595	DNA-templated transcription, initiation
FKQ53_RS22585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FKQ53_RS22595	COG3396	Phenylacetate-CoA oxygenase
FKQ53_RS22600	COG3460	Phenylacetate-CoA oxygenase
FKQ53_RS22605	COG3396	Phenylacetate-CoA oxygenase
FKQ53_RS22610	COG2151	metal-sulfur cluster biosynthetic enzyme
FKQ53_RS22615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FKQ53_RS22635	COG1522	sequence-specific DNA binding
FKQ53_RS22655	COG2814	Major facilitator Superfamily
FKQ53_RS22660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FKQ53_RS22665	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FKQ53_RS22675	COG2226	methyltransferase
FKQ53_RS22690	COG0513	Belongs to the DEAD box helicase family
FKQ53_RS22700	COG2233	PERMEase
FKQ53_RS22710	COG0392	lysyltransferase activity
FKQ53_RS22710	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FKQ53_RS22715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FKQ53_RS22720	COG2827	Endonuclease containing a URI domain
FKQ53_RS22780	COG2814	Major facilitator Superfamily
FKQ53_RS22785	COG4336	lyase activity
FKQ53_RS22790	COG0583	DNA-binding transcription factor activity
FKQ53_RS22800	COG1845	cytochrome c oxidase, subunit III
FKQ53_RS22805	COG1845	cytochrome c oxidase, subunit III
FKQ53_RS22810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FKQ53_RS22815	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FKQ53_RS22840	COG1086	Polysaccharide biosynthesis protein
FKQ53_RS22860	COG0438	transferase activity, transferring glycosyl groups
FKQ53_RS22895	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FKQ53_RS22925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FKQ53_RS22925	COG0543	2 iron, 2 sulfur cluster binding
FKQ53_RS22945	COG0737	Belongs to the 5'-nucleotidase family
FKQ53_RS22955	COG2010	Cytochrome c
FKQ53_RS22975	COG4654	Cytochrome c, class I
FKQ53_RS22980	COG4654	Cytochrome c, class I
FKQ53_RS22985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FKQ53_RS23000	COG0446	pyridine nucleotide-disulphide oxidoreductase
FKQ53_RS23010	COG2823	Periplasmic or secreted lipoprotein
FKQ53_RS23015	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FKQ53_RS23020	COG0792	nuclease activity
FKQ53_RS23030	COG1122	ATPase activity
FKQ53_RS23050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FKQ53_RS23075	COG3622	Belongs to the hyi family
FKQ53_RS23080	COG1832	CoA-binding protein
FKQ53_RS23085	COG0657	acetylesterase activity
FKQ53_RS23095	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FKQ53_RS23100	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FKQ53_RS23115	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FKQ53_RS23115	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FKQ53_RS23115	COG0506	proline dehydrogenase activity
FKQ53_RS23130	COG1115	amino acid carrier protein
FKQ53_RS23140	COG1760	l-serine dehydratase
FKQ53_RS23150	COG0509	glycine decarboxylation via glycine cleavage system
FKQ53_RS23155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FKQ53_RS23165	COG0210	DNA helicase
FKQ53_RS23175	COG3245	cytochrome
FKQ53_RS23195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKQ53_RS23205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FKQ53_RS23210	COG0745	RESPONSE REGULATOR receiver
FKQ53_RS23220	COG3851	Histidine kinase
FKQ53_RS23225	COG2197	response regulator
FKQ53_RS23235	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FKQ53_RS23255	COG2257	FlhB HrpN YscU SpaS Family
FKQ53_RS23260	COG1677	Flagellar hook-basal body complex protein FliE
FKQ53_RS23265	COG1766	The M ring may be actively involved in energy transduction
FKQ53_RS23295	COG1580	Controls the rotational direction of flagella during chemotaxis
FKQ53_RS23300	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FKQ53_RS23335	COG1256	bacterial-type flagellum assembly
FKQ53_RS23345	COG1706	bacterial-type flagellum-dependent cell motility
FKQ53_RS23350	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FKQ53_RS23375	COG1558	bacterial-type flagellum-dependent cell motility
FKQ53_RS23380	COG1815	bacterial-type flagellum-dependent cell motility
FKQ53_RS23410	COG1191	sigma factor activity
FKQ53_RS23425	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FKQ53_RS23435	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FKQ53_RS23440	COG0745	RESPONSE REGULATOR receiver
FKQ53_RS23450	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FKQ53_RS23455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FKQ53_RS23460	COG0840	transmembrane signaling receptor activity
FKQ53_RS23465	COG0840	transmembrane signaling receptor activity
FKQ53_RS23470	COG0840	transmembrane signaling receptor activity
FKQ53_RS23475	COG0835	chemotaxis
FKQ53_RS23480	COG2198	Histidine kinase
FKQ53_RS23480	COG0643	Histidine kinase
FKQ53_RS23485	COG2205	protein histidine kinase activity
FKQ53_RS23485	COG2198	Histidine kinase
FKQ53_RS23485	COG0784	Response regulator, receiver
FKQ53_RS23490	COG1360	Flagellar Motor Protein
FKQ53_RS23510	COG2814	Major facilitator Superfamily
FKQ53_RS23515	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ53_RS23520	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FKQ53_RS23525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FKQ53_RS23530	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FKQ53_RS23545	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FKQ53_RS23555	COG0356	it plays a direct role in the translocation of protons across the membrane
FKQ53_RS23565	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FKQ53_RS23570	COG1475	DNA binding
FKQ53_RS23575	COG1192	Involved in chromosome partitioning
FKQ53_RS23580	COG3040	lipid binding
FKQ53_RS23585	COG0357	Ribosomal RNA small subunit methyltransferase G
FKQ53_RS23590	COG0445	tRNA wobble uridine modification
FKQ53_RS23610	COG1846	Transcriptional regulator
FKQ53_RS23660	COG0583	DNA-binding transcription factor activity
FKQ53_RS23665	COG0114	fumarate hydratase activity
FKQ53_RS23705	COG1522	sequence-specific DNA binding
FKQ53_RS23710	COG4771	TonB-dependent receptor
FKQ53_RS23715	COG3720	iron ion transport
FKQ53_RS23720	COG4558	Periplasmic binding protein
FKQ53_RS23725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FKQ53_RS23735	COG2423	ornithine cyclodeaminase activity
FKQ53_RS23740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FKQ53_RS23760	COG1522	sequence-specific DNA binding
FKQ53_RS23765	COG3186	Phenylalanine-4-hydroxylase
FKQ53_RS23770	COG2154	pterin-4-alpha-carbinolamine dehydratase
FKQ53_RS23795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FKQ53_RS23795	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FKQ53_RS23800	COG0038	chloride channel
FKQ53_RS23805	COG1846	Transcriptional regulator
FKQ53_RS23815	COG2814	Major facilitator Superfamily
FKQ53_RS23820	COG3300	MHYT domain
FKQ53_RS23820	COG5001	Diguanylate cyclase
FKQ53_RS23845	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FKQ53_RS23855	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FKQ53_RS23860	COG0594	ribonuclease P activity
FKQ53_RS23865	COG0230	Belongs to the bacterial ribosomal protein bL34 family