locus-tag	class	description
NA29_RS00010	COG2186	Transcriptional regulator
NA29_RS00020	COG0277	FAD linked oxidase domain protein
NA29_RS00025	COG0247	lactate metabolic process
NA29_RS00035	COG3384	dioxygenase
NA29_RS00040	COG0583	DNA-binding transcription factor activity
NA29_RS00045	COG1253	flavin adenine dinucleotide binding
NA29_RS00055	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NA29_RS00060	COG1280	lysine exporter protein (LysE YggA)
NA29_RS00065	COG1278	Cold shock
NA29_RS00070	COG4942	peptidase
NA29_RS00075	COG2943	transferase activity, transferring hexosyl groups
NA29_RS00080	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NA29_RS00085	COG1280	lysine exporter protein (LysE YggA)
NA29_RS00090	COG0583	DNA-binding transcription factor activity
NA29_RS00100	COG0534	Mate efflux family protein
NA29_RS00110	COG2807	transmembrane transport
NA29_RS00120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NA29_RS00135	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NA29_RS00140	COG0745	RESPONSE REGULATOR receiver
NA29_RS00140	COG3292	Two component regulator propeller
NA29_RS00140	COG2205	protein histidine kinase activity
NA29_RS00145	COG2205	protein histidine kinase activity
NA29_RS00145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NA29_RS00145	COG0784	Response regulator, receiver
NA29_RS00145	COG2198	Histidine kinase
NA29_RS00160	COG0583	DNA-binding transcription factor activity
NA29_RS00185	COG2855	membrane
NA29_RS00200	COG2885	chlorophyll binding
NA29_RS00225	COG0306	phosphate transporter
NA29_RS00235	COG0531	amino acid
NA29_RS00285	COG3781	membrane
NA29_RS00320	COG2814	Major facilitator Superfamily
NA29_RS00325	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NA29_RS00350	COG2249	NAD(P)H dehydrogenase (quinone) activity
NA29_RS00360	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NA29_RS00375	COG0625	glutathione transferase activity
NA29_RS00390	COG3468	outer membrane autotransporter barrel domain protein
NA29_RS00410	COG0583	DNA-binding transcription factor activity
NA29_RS00440	COG2814	Major facilitator Superfamily
NA29_RS00470	COG1968	undecaprenyl-diphosphatase activity
NA29_RS00495	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NA29_RS00520	COG0859	PFAM glycosyl transferase family 9
NA29_RS00535	COG0438	transferase activity, transferring glycosyl groups
NA29_RS00540	COG0438	transferase activity, transferring glycosyl groups
NA29_RS00550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NA29_RS00555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NA29_RS00575	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NA29_RS00580	COG1678	Uncharacterized ACR, COG1678
NA29_RS00590	COG1773	rubredoxin
NA29_RS00605	COG4969	Belongs to the N-Me-Phe pilin family
NA29_RS00610	COG0861	Integral membrane protein TerC family
NA29_RS00615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NA29_RS00620	COG0045	succinate-CoA ligase (ADP-forming) activity
NA29_RS00630	COG2137	regulation of response to DNA damage stimulus
NA29_RS00635	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NA29_RS00645	COG0642	Histidine kinase
NA29_RS00650	COG0477	Major facilitator Superfamily
NA29_RS00660	COG0583	DNA-binding transcription factor activity
NA29_RS00665	COG1942	4-Oxalocrotonate Tautomerase
NA29_RS00675	COG1253	flavin adenine dinucleotide binding
NA29_RS00680	COG0583	DNA-binding transcription factor activity
NA29_RS00685	COG0628	permease
NA29_RS00700	COG1116	anion transmembrane transporter activity
NA29_RS00710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NA29_RS00715	COG0156	8-amino-7-oxononanoate synthase activity
NA29_RS00720	COG1396	sequence-specific DNA binding
NA29_RS00725	COG0840	transmembrane signaling receptor activity
NA29_RS00740	COG1902	pentaerythritol trinitrate reductase activity
NA29_RS00755	COG0668	transmembrane transport
NA29_RS00780	COG3706	GGDEF domain
NA29_RS00785	COG2514	catechol 2,3-dioxygenase activity
NA29_RS00790	COG2719	SpoVR family
NA29_RS00795	COG2718	Belongs to the UPF0229 family
NA29_RS00800	COG2766	serine protein kinase
NA29_RS00805	COG1121	(ABC) transporter
NA29_RS00815	COG0803	Belongs to the bacterial solute-binding protein 9 family
NA29_RS00820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NA29_RS00825	COG1702	phosphate starvation-inducible protein PhoH
NA29_RS00830	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NA29_RS00835	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NA29_RS00845	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NA29_RS00850	COG0752	glycyl-tRNA synthetase alpha subunit
NA29_RS00855	COG0751	glycine-tRNA ligase activity
NA29_RS00860	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NA29_RS00865	COG0204	Acyl-transferase
NA29_RS00875	COG0346	lactoylglutathione lyase activity
NA29_RS00880	COG1773	rubredoxin
NA29_RS00890	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NA29_RS00895	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NA29_RS00900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NA29_RS00905	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NA29_RS00910	COG3178	'Phosphotransferase
NA29_RS00915	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NA29_RS00920	COG0006	proline dipeptidase activity
NA29_RS00925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NA29_RS00935	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NA29_RS00945	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS00975	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NA29_RS00990	COG0495	leucyl-tRNA aminoacylation
NA29_RS00995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NA29_RS01000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NA29_RS01005	COG0735	belongs to the Fur family
NA29_RS01015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NA29_RS01025	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NA29_RS01035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NA29_RS01050	COG4290	ribonuclease
NA29_RS01055	COG0281	malic enzyme
NA29_RS01055	COG0280	phosphate acetyltransferase
NA29_RS01065	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NA29_RS01070	COG1546	Belongs to the CinA family
NA29_RS01075	COG0284	orotidine-5'-phosphate decarboxylase activity
NA29_RS01085	COG0668	transmembrane transport
NA29_RS01090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NA29_RS01095	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NA29_RS01110	COG0557	exoribonuclease II activity
NA29_RS01115	COG3150	esterase
NA29_RS01120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NA29_RS01130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NA29_RS01135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NA29_RS01140	COG0511	ligase activity, forming carbon-carbon bonds
NA29_RS01145	COG0439	Biotin carboxylase
NA29_RS01170	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NA29_RS01170	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NA29_RS01215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NA29_RS01220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NA29_RS01225	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NA29_RS01230	COG2095	MarC family integral membrane protein
NA29_RS01235	COG0442	prolyl-tRNA aminoacylation
NA29_RS01255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NA29_RS01260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NA29_RS01265	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NA29_RS01270	COG0142	geranyltranstransferase activity
NA29_RS01280	COG4536	flavin adenine dinucleotide binding
NA29_RS01310	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NA29_RS01315	COG0494	nUDIX hydrolase
NA29_RS01325	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NA29_RS01330	COG0653	protein targeting
NA29_RS01340	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NA29_RS01355	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NA29_RS01360	COG1181	Belongs to the D-alanine--D-alanine ligase family
NA29_RS01365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NA29_RS01370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NA29_RS01380	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NA29_RS01390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NA29_RS01395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NA29_RS01405	COG3116	cell division
NA29_RS01410	COG0275	rRNA processing
NA29_RS01425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS01440	COG0243	molybdopterin cofactor binding
NA29_RS01445	COG1473	amidohydrolase
NA29_RS01485	COG1024	Enoyl-CoA hydratase
NA29_RS01495	COG0183	Belongs to the thiolase family
NA29_RS01500	COG1024	Enoyl-CoA hydratase
NA29_RS01505	COG2050	protein possibly involved in aromatic compounds catabolism
NA29_RS01515	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NA29_RS01525	COG2967	ApaG domain
NA29_RS01530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NA29_RS01535	COG0546	phosphoglycolate phosphatase activity
NA29_RS01550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NA29_RS01555	COG0842	Transport permease protein
NA29_RS01555	COG1129	ABC transporter
NA29_RS01560	COG0842	Transport permease protein
NA29_RS01570	COG0642	Histidine kinase
NA29_RS01585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NA29_RS01595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NA29_RS01600	COG0134	indole-3-glycerol-phosphate synthase activity
NA29_RS01610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NA29_RS01615	COG4774	siderophore transport
NA29_RS01640	COG0583	DNA-binding transcription factor activity
NA29_RS01655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NA29_RS01660	COG2321	neutral zinc metallopeptidase
NA29_RS01690	COG0463	Glycosyl transferase, family 2
NA29_RS01700	COG0477	Major facilitator Superfamily
NA29_RS01705	COG2261	transglycosylase associated protein
NA29_RS01710	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NA29_RS01715	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NA29_RS01720	COG2890	protein-(glutamine-N5) methyltransferase activity
NA29_RS01725	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NA29_RS01760	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NA29_RS01765	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NA29_RS01770	COG0835	chemotaxis
NA29_RS01780	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS01785	COG0488	(ABC) transporter
NA29_RS01800	COG1408	metallophosphoesterase
NA29_RS01815	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NA29_RS01825	COG2271	Major facilitator Superfamily
NA29_RS01835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NA29_RS01925	COG3045	CreA protein
NA29_RS01930	COG3284	Transcriptional regulator
NA29_RS01940	COG1454	alcohol dehydrogenase
NA29_RS01960	COG2271	Major facilitator Superfamily
NA29_RS01965	COG1737	Transcriptional regulator
NA29_RS01975	COG1473	amidohydrolase
NA29_RS02030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NA29_RS02040	COG3210	domain, Protein
NA29_RS02075	COG4695	Portal protein
NA29_RS02290	COG2969	positive regulation of protein catabolic process
NA29_RS02295	COG0625	glutathione transferase activity
NA29_RS02300	COG2857	Cytochrome c1
NA29_RS02305	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NA29_RS02310	COG0723	plastoquinol--plastocyanin reductase activity
NA29_RS02320	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NA29_RS02325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NA29_RS02330	COG0805	protein transport
NA29_RS02340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NA29_RS02360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NA29_RS02365	COG0107	imidazoleglycerol-phosphate synthase activity
NA29_RS02370	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NA29_RS02375	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NA29_RS02380	COG2095	MarC family integral membrane protein
NA29_RS02385	COG0131	Imidazoleglycerol-phosphate dehydratase
NA29_RS02400	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NA29_RS02420	COG0842	Transport permease protein
NA29_RS02425	COG1131	(ABC) transporter
NA29_RS02445	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NA29_RS02450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NA29_RS02455	COG1127	ABC transporter
NA29_RS02465	COG0352	thiamine-phosphate diphosphorylase activity
NA29_RS02485	COG4178	(ABC) transporter
NA29_RS02490	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS02495	COG2814	Major facilitator Superfamily
NA29_RS02505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NA29_RS02510	COG2271	Major facilitator Superfamily
NA29_RS02520	COG0067	glutamate synthase
NA29_RS02520	COG0070	glutamate synthase
NA29_RS02520	COG0069	glutamate synthase activity
NA29_RS02530	COG3047	cAMP biosynthetic process
NA29_RS02545	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NA29_RS02580	COG1965	Belongs to the frataxin family
NA29_RS02590	COG0019	diaminopimelate decarboxylase activity
NA29_RS02595	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NA29_RS02600	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NA29_RS02605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NA29_RS02610	COG1333	cytochrome c biogenesis protein
NA29_RS02620	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NA29_RS02630	COG4232	protein-disulfide reductase activity
NA29_RS02640	COG0203	ribosomal protein L17
NA29_RS02645	COG0202	RNA polymerase activity
NA29_RS02655	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NA29_RS02660	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NA29_RS02665	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NA29_RS02670	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NA29_RS02675	COG0201	protein transport
NA29_RS02680	COG0200	Binds to the 23S rRNA
NA29_RS02695	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NA29_RS02700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NA29_RS02710	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NA29_RS02715	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NA29_RS02720	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NA29_RS02725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NA29_RS02735	COG0255	Belongs to the universal ribosomal protein uL29 family
NA29_RS02745	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NA29_RS02750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NA29_RS02755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NA29_RS02760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NA29_RS02765	COG0089	rRNA binding
NA29_RS02770	COG0088	Forms part of the polypeptide exit tunnel
NA29_RS02775	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NA29_RS02780	COG0051	transcription antitermination factor activity, RNA binding
NA29_RS02785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NA29_RS02795	COG0049	tRNA binding
NA29_RS02800	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NA29_RS02805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NA29_RS02820	COG2207	Transcriptional regulator
NA29_RS02825	COG1981	membrane
NA29_RS02855	COG0583	DNA-binding transcription factor activity
NA29_RS02870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NA29_RS02895	COG3971	2-oxopent-4-enoate hydratase activity
NA29_RS02900	COG4772	TonB-dependent receptor
NA29_RS02910	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NA29_RS02910	COG0662	Cupin 2, conserved barrel domain protein
NA29_RS02915	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NA29_RS02920	COG0085	RNA polymerase activity
NA29_RS02925	COG0222	ribosome binding
NA29_RS02930	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NA29_RS02940	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NA29_RS02950	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NA29_RS02960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NA29_RS03010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NA29_RS03020	COG3712	iron ion homeostasis
NA29_RS03025	COG1595	DNA-templated transcription, initiation
NA29_RS03055	COG3396	Phenylacetate-CoA oxygenase
NA29_RS03060	COG3460	Phenylacetate-CoA oxygenase
NA29_RS03065	COG3396	Phenylacetate-CoA oxygenase
NA29_RS03070	COG2151	metal-sulfur cluster biosynthetic enzyme
NA29_RS03075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NA29_RS03095	COG1522	sequence-specific DNA binding
NA29_RS03115	COG2814	Major facilitator Superfamily
NA29_RS03120	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NA29_RS03125	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NA29_RS03135	COG2226	methyltransferase
NA29_RS03145	COG4451	ribulose bisphosphate carboxylase, small
NA29_RS03145	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NA29_RS03155	COG0513	Belongs to the DEAD box helicase family
NA29_RS03160	COG0583	DNA-binding transcription factor activity
NA29_RS03165	COG2233	PERMEase
NA29_RS03180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NA29_RS03185	COG2827	Endonuclease containing a URI domain
NA29_RS03235	COG2814	Major facilitator Superfamily
NA29_RS03240	COG4336	lyase activity
NA29_RS03245	COG0583	DNA-binding transcription factor activity
NA29_RS03255	COG1845	cytochrome c oxidase, subunit III
NA29_RS03260	COG1845	cytochrome c oxidase, subunit III
NA29_RS03265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NA29_RS03270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NA29_RS03285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NA29_RS03315	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NA29_RS03330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NA29_RS03335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NA29_RS03350	COG0737	Belongs to the 5'-nucleotidase family
NA29_RS03380	COG4654	Cytochrome c, class I
NA29_RS03385	COG4654	Cytochrome c, class I
NA29_RS03390	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NA29_RS03405	COG0446	pyridine nucleotide-disulphide oxidoreductase
NA29_RS03415	COG2823	Periplasmic or secreted lipoprotein
NA29_RS03420	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NA29_RS03435	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NA29_RS03455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NA29_RS03465	COG1393	Belongs to the ArsC family
NA29_RS03480	COG3622	Belongs to the hyi family
NA29_RS03485	COG1832	CoA-binding protein
NA29_RS03490	COG0657	acetylesterase activity
NA29_RS03500	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NA29_RS03505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NA29_RS03520	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NA29_RS03520	COG0506	proline dehydrogenase activity
NA29_RS03520	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NA29_RS03525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NA29_RS03535	COG1115	amino acid carrier protein
NA29_RS03545	COG1760	l-serine dehydratase
NA29_RS03555	COG0509	glycine decarboxylation via glycine cleavage system
NA29_RS03560	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NA29_RS03570	COG0210	DNA helicase
NA29_RS03580	COG3245	cytochrome
NA29_RS03605	COG2205	protein histidine kinase activity
NA29_RS03610	COG0745	RESPONSE REGULATOR receiver
NA29_RS03625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NA29_RS03635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NA29_RS03640	COG0745	RESPONSE REGULATOR receiver
NA29_RS03650	COG3851	Histidine kinase
NA29_RS03655	COG2197	response regulator
NA29_RS03685	COG2257	FlhB HrpN YscU SpaS Family
NA29_RS03730	COG1580	Controls the rotational direction of flagella during chemotaxis
NA29_RS03750	COG1338	Plays a role in the flagellum-specific transport system
NA29_RS03770	COG1256	bacterial-type flagellum assembly
NA29_RS03775	COG3951	Flagellar rod assembly protein muramidase FlgJ
NA29_RS03775	COG1705	Flagellar rod assembly protein muramidase FlgJ
NA29_RS03780	COG1706	bacterial-type flagellum-dependent cell motility
NA29_RS03785	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NA29_RS03795	COG4787	bacterial-type flagellum-dependent cell motility
NA29_RS03810	COG1558	bacterial-type flagellum-dependent cell motility
NA29_RS03815	COG1815	bacterial-type flagellum-dependent cell motility
NA29_RS03845	COG0641	radical SAM
NA29_RS03850	COG1191	sigma factor activity
NA29_RS03865	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NA29_RS03875	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NA29_RS03880	COG0745	RESPONSE REGULATOR receiver
NA29_RS03890	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NA29_RS03895	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NA29_RS03900	COG0840	transmembrane signaling receptor activity
NA29_RS03905	COG0840	transmembrane signaling receptor activity
NA29_RS03910	COG0840	transmembrane signaling receptor activity
NA29_RS03920	COG2198	Histidine kinase
NA29_RS03920	COG0643	Histidine kinase
NA29_RS03925	COG0784	Response regulator, receiver
NA29_RS03925	COG2198	Histidine kinase
NA29_RS03925	COG2205	protein histidine kinase activity
NA29_RS03930	COG1360	Flagellar Motor Protein
NA29_RS03950	COG2814	Major facilitator Superfamily
NA29_RS03955	COG0318	PFAM AMP-dependent synthetase and ligase
NA29_RS03960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NA29_RS03965	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NA29_RS03970	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NA29_RS03985	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NA29_RS03995	COG0356	it plays a direct role in the translocation of protons across the membrane
NA29_RS04005	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NA29_RS04010	COG1475	DNA binding
NA29_RS04015	COG1192	Involved in chromosome partitioning
NA29_RS04020	COG3040	lipid binding
NA29_RS04025	COG0357	Ribosomal RNA small subunit methyltransferase G
NA29_RS04030	COG0445	tRNA wobble uridine modification
NA29_RS04050	COG1846	Transcriptional regulator
NA29_RS04060	COG0730	response to heat
NA29_RS04100	COG0583	DNA-binding transcription factor activity
NA29_RS04105	COG0114	fumarate hydratase activity
NA29_RS04120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NA29_RS04140	COG1522	sequence-specific DNA binding
NA29_RS04145	COG4771	TonB-dependent receptor
NA29_RS04150	COG3720	iron ion transport
NA29_RS04155	COG4558	Periplasmic binding protein
NA29_RS04165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NA29_RS04175	COG2423	ornithine cyclodeaminase activity
NA29_RS04180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NA29_RS04200	COG1522	sequence-specific DNA binding
NA29_RS04205	COG3186	Phenylalanine-4-hydroxylase
NA29_RS04210	COG2154	pterin-4-alpha-carbinolamine dehydratase
NA29_RS04235	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NA29_RS04235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NA29_RS04240	COG0038	chloride channel
NA29_RS04245	COG1846	Transcriptional regulator
NA29_RS04255	COG2814	Major facilitator Superfamily
NA29_RS04260	COG3300	MHYT domain
NA29_RS04260	COG5001	Diguanylate cyclase
NA29_RS04295	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NA29_RS04300	COG0706	membrane insertase activity
NA29_RS04305	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NA29_RS04310	COG0594	ribonuclease P activity
NA29_RS04315	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NA29_RS04325	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NA29_RS04330	COG0592	DNA-directed DNA polymerase activity
NA29_RS04345	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NA29_RS04365	COG2851	Citrate transporter
NA29_RS04380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NA29_RS04400	COG0477	Major facilitator Superfamily
NA29_RS04415	COG0840	transmembrane signaling receptor activity
NA29_RS04445	COG3842	ATPase activity
NA29_RS04470	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NA29_RS04480	COG0596	Alpha beta hydrolase
NA29_RS04485	COG1764	response to oxidative stress
NA29_RS04490	COG1846	Transcriptional regulator
NA29_RS04495	COG0583	DNA-binding transcription factor activity
NA29_RS04505	COG0765	amino acid transport
NA29_RS04510	COG0765	amino acid transport
NA29_RS04545	COG1252	NADH dehydrogenase
NA29_RS04550	COG1309	transcriptional regulator
NA29_RS04570	COG4774	siderophore transport
NA29_RS04585	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NA29_RS04605	COG1968	undecaprenyl-diphosphatase activity
NA29_RS04610	COG0583	DNA-binding transcription factor activity
NA29_RS04660	COG2252	PERMEase
NA29_RS04665	COG0583	DNA-binding transcription factor activity
NA29_RS04685	COG2733	membrane
NA29_RS04695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NA29_RS04725	COG0583	DNA-binding transcription factor activity
NA29_RS04735	COG0583	DNA-binding transcription factor activity
NA29_RS04740	COG2814	Major facilitator Superfamily
NA29_RS04745	COG2005	Transcriptional regulator
NA29_RS04745	COG3585	molybdate ion transport
NA29_RS04750	COG2200	EAL domain
NA29_RS04750	COG2771	luxR family
NA29_RS04755	COG2223	nitrite transmembrane transporter activity
NA29_RS04780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NA29_RS04785	COG3246	L-lysine catabolic process to acetate
NA29_RS04790	COG0840	transmembrane signaling receptor activity
NA29_RS04800	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NA29_RS04800	COG0457	Tetratricopeptide repeat
NA29_RS04805	COG0835	chemotaxis
NA29_RS04815	COG2201	protein-glutamate methylesterase activity
NA29_RS04820	COG5001	Diguanylate cyclase
NA29_RS04820	COG4251	negative regulation of phosphorylation
NA29_RS04820	COG3706	GGDEF domain
NA29_RS04820	COG2203	Gaf domain
NA29_RS04845	COG1473	amidohydrolase
NA29_RS04855	COG0183	Belongs to the thiolase family
NA29_RS04895	COG1802	Transcriptional regulator
NA29_RS04900	COG2957	Belongs to the agmatine deiminase family
NA29_RS04910	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NA29_RS04910	COG1672	PFAM Archaeal ATPase
NA29_RS04915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NA29_RS04920	COG4774	siderophore transport
NA29_RS04925	COG3128	pkhd-type hydroxylase
NA29_RS04955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NA29_RS04960	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NA29_RS04985	COG1966	Carbon starvation protein
NA29_RS04990	COG2879	small protein
NA29_RS05000	COG0583	DNA-binding transcription factor activity
NA29_RS05015	COG0758	DNA mediated transformation
NA29_RS05020	COG0242	peptide deformylase activity
NA29_RS05030	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NA29_RS05035	COG0501	Belongs to the peptidase M48B family
NA29_RS05050	COG5000	phosphorelay sensor kinase activity
NA29_RS05055	COG2204	response regulator
NA29_RS05055	COG2204	response regulator
NA29_RS05070	COG0602	queuosine metabolic process
NA29_RS05075	COG0720	synthase
NA29_RS05125	COG2207	Transcriptional regulator
NA29_RS05160	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NA29_RS05250	COG0772	Belongs to the SEDS family
NA29_RS05255	COG0768	penicillin binding
NA29_RS05265	COG1792	Involved in formation and maintenance of cell shape
NA29_RS05270	COG1077	Cell shape determining protein MreB Mrl
NA29_RS05275	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NA29_RS05290	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NA29_RS05295	COG2326	polyphosphate kinase activity
NA29_RS05300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NA29_RS05355	COG1960	acyl-CoA dehydrogenase activity
NA29_RS05365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NA29_RS05370	COG1560	Kdo2-lipid A biosynthetic process
NA29_RS05375	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NA29_RS05385	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NA29_RS05390	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NA29_RS05405	COG0523	cobalamin synthesis protein
NA29_RS05420	COG4206	TonB-dependent receptor
NA29_RS05425	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NA29_RS05430	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NA29_RS05435	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NA29_RS05480	COG0477	Major facilitator Superfamily
NA29_RS05495	COG2188	Transcriptional regulator
NA29_RS05505	COG3384	dioxygenase
NA29_RS05515	COG0683	leucine binding
NA29_RS05530	COG1129	ABC transporter
NA29_RS05540	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NA29_RS05545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NA29_RS05550	COG2828	Protein conserved in bacteria
NA29_RS05565	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS05570	COG2814	Major facilitator Superfamily
NA29_RS05580	COG1309	transcriptional regulator
NA29_RS05585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NA29_RS05590	COG2813	Specifically methylates the guanine in position
NA29_RS05590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NA29_RS05595	COG2814	Major facilitator Superfamily
NA29_RS05605	COG0708	Exodeoxyribonuclease III
NA29_RS05610	COG0583	DNA-binding transcription factor activity
NA29_RS05615	COG1380	Effector of murein hydrolase LrgA
NA29_RS05620	COG1346	cytolysis
NA29_RS05625	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NA29_RS05630	COG1950	PFAM Membrane protein of
NA29_RS05640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NA29_RS05645	COG0747	negative chemotaxis
NA29_RS05650	COG0601	transmembrane transport
NA29_RS05655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NA29_RS05660	COG0444	Belongs to the ABC transporter superfamily
NA29_RS05665	COG4608	Belongs to the ABC transporter superfamily
NA29_RS05675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NA29_RS05680	COG0830	nickel cation binding
NA29_RS05690	COG0804	urea catabolic process
NA29_RS05695	COG0832	Belongs to the urease beta subunit family
NA29_RS05705	COG0831	urea catabolic process
NA29_RS05710	COG1126	abc transporter atp-binding protein
NA29_RS05715	COG0765	amino acid transport
NA29_RS05720	COG0765	amino acid transport
NA29_RS05735	COG1137	ATPase activity
NA29_RS05760	COG2814	Major facilitator Superfamily
NA29_RS05775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NA29_RS05780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NA29_RS05790	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NA29_RS05795	COG1984	allophanate hydrolase subunit 2
NA29_RS05800	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NA29_RS05825	COG0617	tRNA 3'-terminal CCA addition
NA29_RS05860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NA29_RS05865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NA29_RS05885	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS05900	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS05905	COG3842	ATPase activity
NA29_RS05925	COG0642	Histidine kinase
NA29_RS05930	COG1104	cysteine desulfurase activity
NA29_RS05940	COG0038	chloride channel
NA29_RS05990	COG0583	DNA-binding transcription factor activity
NA29_RS06005	COG0625	glutathione transferase activity
NA29_RS06010	COG0583	DNA-binding transcription factor activity
NA29_RS06040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NA29_RS06055	COG0583	DNA-binding transcription factor activity
NA29_RS06080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NA29_RS06080	COG2169	Transcriptional regulator
NA29_RS06095	COG0523	cobalamin synthesis protein
NA29_RS06105	COG1741	Belongs to the pirin family
NA29_RS06115	COG1739	Uncharacterized protein family UPF0029
NA29_RS06125	COG2132	Multicopper oxidase
NA29_RS06170	COG1250	3-hydroxyacyl-CoA dehydrogenase
NA29_RS06235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NA29_RS06240	COG4681	YaeQ
NA29_RS06260	COG0697	spore germination
NA29_RS06265	COG3706	GGDEF domain
NA29_RS06280	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS06285	COG2084	Dehydrogenase
NA29_RS06295	COG4770	biotin carboxylase activity
NA29_RS06300	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NA29_RS06305	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NA29_RS06310	COG0156	8-amino-7-oxononanoate synthase activity
NA29_RS06320	COG1024	Enoyl-CoA hydratase
NA29_RS06325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NA29_RS06330	COG3012	SEC-C Motif Domain Protein
NA29_RS06340	COG0300	oxidoreductase activity
NA29_RS06345	COG0183	Belongs to the thiolase family
NA29_RS06350	COG0288	reversible hydration of carbon dioxide
NA29_RS06355	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NA29_RS06360	COG1960	acyl-CoA dehydrogenase activity
NA29_RS06370	COG0789	Transcriptional regulator
NA29_RS06375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NA29_RS06395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NA29_RS06405	COG0018	arginyl-trna synthetase
NA29_RS06420	COG1285	pathogenesis
NA29_RS06425	COG1410	methionine synthase
NA29_RS06425	COG0646	methionine synthase
NA29_RS06445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NA29_RS06490	COG1279	arginine transmembrane transporter activity
NA29_RS06510	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NA29_RS06525	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NA29_RS06535	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NA29_RS06540	COG1127	ABC transporter
NA29_RS06560	COG2814	Major facilitator Superfamily
NA29_RS06575	COG1686	Belongs to the peptidase S11 family
NA29_RS06580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NA29_RS06585	COG2921	Belongs to the UPF0250 family
NA29_RS06590	COG0583	DNA-binding transcription factor activity
NA29_RS06605	COG0321	lipoyl(octanoyl) transferase activity
NA29_RS06630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NA29_RS06635	COG1116	anion transmembrane transporter activity
NA29_RS06640	COG1301	dicarboxylic acid transport
NA29_RS06645	COG4191	Histidine kinase
NA29_RS06650	COG2204	response regulator
NA29_RS06655	COG0288	reversible hydration of carbon dioxide
NA29_RS06675	COG0606	chelatase, subunit chli
NA29_RS06680	COG2960	long-chain fatty acid transporting porin activity
NA29_RS06690	COG0347	Belongs to the P(II) protein family
NA29_RS06695	COG0004	ammonium transporteR
NA29_RS06710	COG0189	ligase activity
NA29_RS06720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NA29_RS06725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NA29_RS06735	COG0793	Belongs to the peptidase S41A family
NA29_RS06745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NA29_RS06750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NA29_RS06755	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NA29_RS06765	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NA29_RS06775	COG1040	competence protein
NA29_RS06780	COG2226	methyltransferase
NA29_RS06785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NA29_RS06790	COG2423	ornithine cyclodeaminase activity
NA29_RS06795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NA29_RS06805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NA29_RS06810	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NA29_RS06820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NA29_RS06825	COG2771	luxR family
NA29_RS06840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NA29_RS06845	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NA29_RS06875	COG1612	heme a metabolic process
NA29_RS06885	COG1999	signal sequence binding
NA29_RS06895	COG1294	oxidase, subunit
NA29_RS06910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NA29_RS06920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NA29_RS06925	COG0625	glutathione transferase activity
NA29_RS06940	COG0612	Peptidase, M16
NA29_RS06945	COG0612	Peptidase, M16
NA29_RS06955	COG1131	(ABC) transporter
NA29_RS06960	COG0742	ribosomal rna small subunit methyltransferase
NA29_RS06965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NA29_RS06975	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NA29_RS06980	COG0193	aminoacyl-tRNA hydrolase activity
NA29_RS06985	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NA29_RS06990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NA29_RS07005	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NA29_RS07020	COG1194	a g-specific adenine glycosylase
NA29_RS07025	COG1660	Displays ATPase and GTPase activities
NA29_RS07035	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NA29_RS07045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NA29_RS07050	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NA29_RS07055	COG1137	ATPase activity
NA29_RS07070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NA29_RS07085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NA29_RS07100	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NA29_RS07105	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NA29_RS07110	COG3639	organic phosphonate transmembrane transporter activity
NA29_RS07115	COG3454	Phosphonate metabolism
NA29_RS07120	COG4778	phosphonate C-P lyase system protein PhnL
NA29_RS07125	COG4107	phosphonate C-P lyase system protein PhnK
NA29_RS07130	COG3627	carbon phosphorus lyase activity
NA29_RS07135	COG3626	phosphonate metabolism
NA29_RS07140	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
NA29_RS07145	COG3624	Phosphonate C-P lyase system protein PhnG
NA29_RS07150	COG2188	Transcriptional regulator
NA29_RS07155	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
NA29_RS07170	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NA29_RS07190	COG0477	Major facilitator Superfamily
NA29_RS07205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NA29_RS07215	COG3842	ATPase activity
NA29_RS07220	COG1840	ABC-type Fe3 transport system, periplasmic component
NA29_RS07235	COG1012	belongs to the aldehyde dehydrogenase family
NA29_RS07240	COG1283	sodium-dependent phosphate transmembrane transporter activity
NA29_RS07280	COG2814	Major facilitator Superfamily
NA29_RS07285	COG0629	single-stranded DNA binding
NA29_RS07300	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NA29_RS07360	COG1752	Esterase of the alpha-beta hydrolase superfamily
NA29_RS07365	COG2205	protein histidine kinase activity
NA29_RS07370	COG0745	RESPONSE REGULATOR receiver
NA29_RS07375	COG2259	Doxx family
NA29_RS07395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NA29_RS07400	COG0765	amino acid transport
NA29_RS07410	COG1609	Transcriptional regulator
NA29_RS07415	COG3540	Alkaline phosphatase
NA29_RS07420	COG1418	mRNA catabolic process
NA29_RS07445	COG1473	amidohydrolase
NA29_RS07450	COG1802	Transcriptional regulator
NA29_RS07460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NA29_RS07465	COG1012	belongs to the aldehyde dehydrogenase family
NA29_RS07495	COG0625	glutathione transferase activity
NA29_RS07525	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS07530	COG0667	Aldo Keto reductase
NA29_RS07535	COG2207	Transcriptional regulator
NA29_RS07540	COG3077	Addiction module antitoxin, RelB DinJ family
NA29_RS07565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NA29_RS07570	COG2271	Major facilitator Superfamily
NA29_RS07575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NA29_RS07580	COG0625	glutathione transferase activity
NA29_RS07605	COG0583	DNA-binding transcription factor activity
NA29_RS07620	COG0477	Major facilitator Superfamily
NA29_RS07625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NA29_RS07635	COG0583	DNA-binding transcription factor activity
NA29_RS07645	COG0235	Class ii aldolase
NA29_RS07655	COG0583	DNA-binding transcription factor activity
NA29_RS07660	COG0477	Major facilitator Superfamily
NA29_RS07670	COG0583	DNA-binding transcription factor activity
NA29_RS07710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NA29_RS07720	COG0765	amino acid transport
NA29_RS07725	COG0010	Belongs to the arginase family
NA29_RS07730	COG1126	abc transporter atp-binding protein
NA29_RS07745	COG1733	regulation of RNA biosynthetic process
NA29_RS07770	COG1309	transcriptional regulator
NA29_RS07780	COG0477	Major facilitator Superfamily
NA29_RS07795	COG1053	succinate dehydrogenase
NA29_RS07795	COG3976	FMN-binding domain protein
NA29_RS07805	COG1414	Transcriptional regulator
NA29_RS07810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NA29_RS07815	COG3384	dioxygenase
NA29_RS07820	COG3971	2-oxopent-4-enoate hydratase activity
NA29_RS07825	COG2814	Major facilitator Superfamily
NA29_RS07830	COG2267	carboxylic ester hydrolase activity
NA29_RS07870	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS07875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NA29_RS07890	COG2610	gluconate transmembrane transporter activity
NA29_RS07900	COG1733	regulation of RNA biosynthetic process
NA29_RS07905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NA29_RS07910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NA29_RS07915	COG0656	L-ascorbic acid biosynthetic process
NA29_RS07920	COG3038	cytochrome b561
NA29_RS07925	COG4771	TonB-dependent receptor
NA29_RS07935	COG3047	cAMP biosynthetic process
NA29_RS07940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NA29_RS07945	COG0583	DNA-binding transcription factor activity
NA29_RS07965	COG0625	glutathione transferase activity
NA29_RS07995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NA29_RS08000	COG0183	Belongs to the thiolase family
NA29_RS08005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NA29_RS08015	COG1414	Transcriptional regulator
NA29_RS08055	COG1846	Transcriptional regulator
NA29_RS08065	COG2814	Major facilitator Superfamily
NA29_RS08080	COG0583	DNA-binding transcription factor activity
NA29_RS08090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NA29_RS08100	COG0583	DNA-binding transcription factor activity
NA29_RS08105	COG1902	pentaerythritol trinitrate reductase activity
NA29_RS08130	COG1414	Transcriptional regulator
NA29_RS08135	COG1414	Transcriptional regulator
NA29_RS08150	COG0730	response to heat
NA29_RS08155	COG0280	phosphate acetyltransferase
NA29_RS08190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NA29_RS08220	COG1113	amino acid transport
NA29_RS08225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NA29_RS08230	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NA29_RS08235	COG4521	taurine ABC transporter
NA29_RS08240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NA29_RS08245	COG0625	glutathione transferase activity
NA29_RS08255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS08265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NA29_RS08280	COG1024	Enoyl-CoA hydratase
NA29_RS08285	COG0318	PFAM AMP-dependent synthetase and ligase
NA29_RS08290	COG2271	Major facilitator Superfamily
NA29_RS08305	COG0596	Alpha beta hydrolase
NA29_RS08315	COG0642	Histidine kinase
NA29_RS08325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NA29_RS08330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NA29_RS08335	COG1126	abc transporter atp-binding protein
NA29_RS08340	COG0765	amino acid transport
NA29_RS08345	COG0583	DNA-binding transcription factor activity
NA29_RS08350	COG0697	spore germination
NA29_RS08355	COG1902	pentaerythritol trinitrate reductase activity
NA29_RS08360	COG0656	L-ascorbic acid biosynthetic process
NA29_RS08365	COG2814	Major facilitator Superfamily
NA29_RS08370	COG0583	DNA-binding transcription factor activity
NA29_RS08380	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NA29_RS08395	COG0833	amino acid
NA29_RS08400	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NA29_RS08410	COG1595	DNA-templated transcription, initiation
NA29_RS08420	COG0583	DNA-binding transcription factor activity
NA29_RS08425	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NA29_RS08440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NA29_RS08455	COG0583	DNA-binding transcription factor activity
NA29_RS08465	COG1473	amidohydrolase
NA29_RS08495	COG0531	amino acid
NA29_RS08525	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS08530	COG2211	Major facilitator Superfamily
NA29_RS08555	COG0477	Major facilitator Superfamily
NA29_RS08575	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NA29_RS08595	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NA29_RS08595	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NA29_RS08605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NA29_RS08615	COG1238	metal cluster binding
NA29_RS08635	COG0025	NhaP-type Na H and K H
NA29_RS08650	COG2226	methyltransferase
NA29_RS08665	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NA29_RS08690	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NA29_RS08695	COG0494	nUDIX hydrolase
NA29_RS08700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NA29_RS08710	COG1960	acyl-CoA dehydrogenase activity
NA29_RS08715	COG1024	Enoyl-CoA hydratase
NA29_RS08715	COG1250	3-hydroxyacyl-CoA dehydrogenase
NA29_RS08720	COG0183	Belongs to the thiolase family
NA29_RS08735	COG5265	(ABC) transporter
NA29_RS08745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NA29_RS08755	COG0765	amino acid transport
NA29_RS08760	COG0765	amino acid transport
NA29_RS08765	COG1126	abc transporter atp-binding protein
NA29_RS08770	COG0121	glutamine amidotransferase
NA29_RS08775	COG0418	dihydroorotase activity
NA29_RS08790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NA29_RS08795	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NA29_RS08800	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NA29_RS08805	COG0316	Belongs to the HesB IscA family
NA29_RS08810	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NA29_RS08815	COG0739	heme binding
NA29_RS08830	COG1881	PFAM PEBP family protein
NA29_RS08845	COG2255	four-way junction helicase activity
NA29_RS08850	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NA29_RS08855	COG1981	membrane
NA29_RS08865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NA29_RS08870	COG1737	Transcriptional regulator
NA29_RS08880	COG0800	Aldolase
NA29_RS08890	COG3265	gluconokinase activity
NA29_RS08905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NA29_RS08930	COG0482	sulfurtransferase activity
NA29_RS08935	COG0069	glutamate synthase activity
NA29_RS08940	COG2207	Transcriptional regulator
NA29_RS09005	COG2197	response regulator
NA29_RS09075	COG3909	cytochrome
NA29_RS09095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NA29_RS09100	COG1862	Preprotein translocase
NA29_RS09105	COG0343	queuine tRNA-ribosyltransferase activity
NA29_RS09110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NA29_RS09115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NA29_RS09125	COG0753	catalase activity
NA29_RS09130	COG0352	thiamine-phosphate diphosphorylase activity
NA29_RS09135	COG0783	Belongs to the Dps family
NA29_RS09140	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NA29_RS09145	COG3193	protein, possibly involved in utilization of glycolate and propanediol
NA29_RS09165	COG1741	Belongs to the pirin family
NA29_RS09190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NA29_RS09215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NA29_RS09225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NA29_RS09240	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NA29_RS09280	COG2351	hydroxyisourate hydrolase activity
NA29_RS09300	COG1172	Belongs to the binding-protein-dependent transport system permease family
NA29_RS09315	COG1802	Transcriptional regulator
NA29_RS09320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NA29_RS09325	COG2814	Major facilitator Superfamily
NA29_RS09325	COG0477	Major facilitator Superfamily
NA29_RS09370	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NA29_RS09375	COG4566	intracellular signal transduction
NA29_RS09390	COG0811	peptide transport
NA29_RS09480	COG4166	transmembrane transport
NA29_RS09490	COG0444	Belongs to the ABC transporter superfamily
NA29_RS09500	COG0601	transmembrane transport
NA29_RS09505	COG2072	flavoprotein involved in K transport
NA29_RS09515	COG2176	DNA-directed DNA polymerase activity
NA29_RS09530	COG3706	GGDEF domain
NA29_RS09540	COG1802	Transcriptional regulator
NA29_RS09550	COG0596	Alpha beta hydrolase
NA29_RS09595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NA29_RS09605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NA29_RS09610	COG0745	RESPONSE REGULATOR receiver
NA29_RS09615	COG2205	protein histidine kinase activity
NA29_RS09625	COG0471	metal ion transport
NA29_RS09650	COG1012	belongs to the aldehyde dehydrogenase family
NA29_RS09660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NA29_RS09665	COG1012	belongs to the aldehyde dehydrogenase family
NA29_RS09670	COG1522	sequence-specific DNA binding
NA29_RS09675	COG3608	succinylglutamate desuccinylase aspartoacylase
NA29_RS09700	COG1012	belongs to the aldehyde dehydrogenase family
NA29_RS09705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NA29_RS09720	COG4175	Glycine betaine
NA29_RS09725	COG4176	ABC-type proline glycine betaine transport system permease component
NA29_RS09730	COG2113	Glycine betaine
NA29_RS09750	COG0583	DNA-binding transcription factor activity
NA29_RS09760	COG1846	Transcriptional regulator
NA29_RS09765	COG0697	spore germination
NA29_RS09770	COG0315	cyclic pyranopterin monophosphate synthase activity
NA29_RS09785	COG0429	hydrolase of the alpha beta-hydrolase fold
NA29_RS09815	COG0126	phosphoglycerate kinase activity
NA29_RS09820	COG0469	pyruvate kinase activity
NA29_RS09840	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NA29_RS09845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NA29_RS09850	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NA29_RS09855	COG0009	L-threonylcarbamoyladenylate synthase
NA29_RS09865	COG2027	D-alanyl-D-alanine carboxypeptidase
NA29_RS09885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NA29_RS09895	COG3608	succinylglutamate desuccinylase aspartoacylase
NA29_RS09895	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NA29_RS09910	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
NA29_RS09915	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NA29_RS09925	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NA29_RS09930	COG4149	molybdate abc transporter
NA29_RS09935	COG0725	ABC transporter, periplasmic molybdate-binding protein
NA29_RS09940	COG1309	transcriptional regulator
NA29_RS09950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NA29_RS09995	COG4575	ribosome binding
NA29_RS10000	COG0450	alkyl hydroperoxide reductase
NA29_RS10005	COG1960	acyl-CoA dehydrogenase activity
NA29_RS10015	COG3483	tryptophan 2,3-dioxygenase activity
NA29_RS10025	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NA29_RS10035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NA29_RS10040	COG2309	aminopeptidase activity
NA29_RS10045	COG2267	carboxylic ester hydrolase activity
NA29_RS10050	COG1960	acyl-CoA dehydrogenase activity
NA29_RS10065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NA29_RS10070	COG0765	amino acid transport
NA29_RS10075	COG1126	abc transporter atp-binding protein
NA29_RS10080	COG0010	Belongs to the arginase family
NA29_RS10085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NA29_RS10100	COG0477	Major facilitator Superfamily
NA29_RS10105	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NA29_RS10115	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NA29_RS10120	COG0259	pyridoxamine-phosphate oxidase activity
NA29_RS10125	COG2982	Protein involved in outer membrane biogenesis
NA29_RS10130	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NA29_RS10135	COG0318	PFAM AMP-dependent synthetase and ligase
NA29_RS10165	COG1309	transcriptional regulator
NA29_RS10170	COG1113	amino acid transport
NA29_RS10175	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS10180	COG1522	sequence-specific DNA binding
NA29_RS10185	COG1304	FMN binding
NA29_RS10190	COG1724	mRNA binding
NA29_RS10195	COG1598	PFAM Uncharacterised protein family UPF0150
NA29_RS10205	COG0583	DNA-binding transcription factor activity
NA29_RS10220	COG0154	amidase activity
NA29_RS10245	COG1116	anion transmembrane transporter activity
NA29_RS10255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NA29_RS10265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NA29_RS10270	COG1960	acyl-CoA dehydrogenase activity
NA29_RS10280	COG2897	thiosulfate sulfurtransferase activity
NA29_RS10335	COG5492	domain, Protein
NA29_RS10350	COG3916	Acyl-homoserine-lactone synthase
NA29_RS10355	COG2197	response regulator
NA29_RS10365	COG1454	alcohol dehydrogenase
NA29_RS10400	COG1414	Transcriptional regulator
NA29_RS10415	COG1802	Transcriptional regulator
NA29_RS10420	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NA29_RS10425	COG2271	Major facilitator Superfamily
NA29_RS10430	COG0247	lactate metabolic process
NA29_RS10430	COG0277	FAD linked oxidase domain protein
NA29_RS10480	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS10515	COG0456	acetyltransferase
NA29_RS10530	COG0842	Transport permease protein
NA29_RS10535	COG1131	(ABC) transporter
NA29_RS10550	COG0583	DNA-binding transcription factor activity
NA29_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS10565	COG1522	sequence-specific DNA binding
NA29_RS10580	COG1764	response to oxidative stress
NA29_RS10590	COG2900	Belongs to the SlyX family
NA29_RS10595	COG1742	UPF0060 membrane protein
NA29_RS10610	COG0583	DNA-binding transcription factor activity
NA29_RS10620	COG1522	sequence-specific DNA binding
NA29_RS10630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NA29_RS10640	COG1845	cytochrome c oxidase, subunit III
NA29_RS10645	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NA29_RS10685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NA29_RS10690	COG1305	Transglutaminase-like
NA29_RS10700	COG2267	carboxylic ester hydrolase activity
NA29_RS10720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NA29_RS10740	COG0693	protein deglycase activity
NA29_RS10750	COG0583	DNA-binding transcription factor activity
NA29_RS10755	COG0604	alcohol dehydrogenase
NA29_RS10785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS10790	COG0583	DNA-binding transcription factor activity
NA29_RS10805	COG1012	belongs to the aldehyde dehydrogenase family
NA29_RS10835	COG0583	DNA-binding transcription factor activity
NA29_RS10880	COG1917	Cupin 2, conserved barrel domain protein
NA29_RS10915	COG1175	transmembrane transport
NA29_RS10925	COG3842	ATPase activity
NA29_RS10930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NA29_RS10965	COG0540	Belongs to the ATCase OTCase family
NA29_RS10975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NA29_RS10980	COG2271	Major facilitator Superfamily
NA29_RS10985	COG0500	methyltransferase
NA29_RS10990	COG0583	DNA-binding transcription factor activity
NA29_RS11000	COG0308	aminopeptidase N
NA29_RS11010	COG2119	membrane
NA29_RS11015	COG0402	S-adenosylhomocysteine deaminase activity
NA29_RS11020	COG2252	PERMEase
NA29_RS11025	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NA29_RS11035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NA29_RS11050	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NA29_RS11070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NA29_RS11070	COG4651	solute:proton antiporter activity
NA29_RS11085	COG2608	mercury ion transmembrane transporter activity
NA29_RS11090	COG2217	Heavy metal translocating P-type atpase
NA29_RS11095	COG3568	Endonuclease Exonuclease Phosphatase
NA29_RS11100	COG0789	Transcriptional regulator
NA29_RS11130	COG1914	H( )-stimulated, divalent metal cation uptake system
NA29_RS11145	COG0587	DNA-directed DNA polymerase activity
NA29_RS11155	COG2233	PERMEase
NA29_RS11180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NA29_RS11195	COG0513	Belongs to the DEAD box helicase family
NA29_RS11200	COG2902	Dehydrogenase
NA29_RS11225	COG2252	PERMEase
NA29_RS11230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS11245	COG1283	sodium-dependent phosphate transmembrane transporter activity
NA29_RS11255	COG2271	Major facilitator Superfamily
NA29_RS11290	COG0328	RNA-DNA hybrid ribonuclease activity
NA29_RS11300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NA29_RS11305	COG1388	LysM domain
NA29_RS11305	COG0741	lytic transglycosylase activity
NA29_RS11335	COG2814	Major facilitator Superfamily
NA29_RS11340	COG0583	DNA-binding transcription factor activity
NA29_RS11390	COG3210	domain, Protein
NA29_RS11410	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS11415	COG1024	Enoyl-CoA hydratase
NA29_RS11445	COG4266	Belongs to the allantoicase family
NA29_RS11450	COG1301	dicarboxylic acid transport
NA29_RS11470	COG0505	Belongs to the CarA family
NA29_RS11480	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NA29_RS11485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NA29_RS11495	COG1534	Rna-binding protein
NA29_RS11505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NA29_RS11520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NA29_RS11525	COG0573	inorganic phosphate transmembrane transporter activity
NA29_RS11530	COG0581	inorganic phosphate transmembrane transporter activity
NA29_RS11535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NA29_RS11545	COG0745	RESPONSE REGULATOR receiver
NA29_RS11555	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NA29_RS11570	COG2062	phosphohistidine phosphatase, SixA
NA29_RS11585	COG2963	transposase activity
NA29_RS11595	COG3609	addiction module antidote protein, CC2985 family
NA29_RS11610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NA29_RS11625	COG1846	Transcriptional regulator
NA29_RS11630	COG2010	Cytochrome c
NA29_RS11630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NA29_RS11635	COG1335	isochorismatase
NA29_RS11640	COG2309	aminopeptidase activity
NA29_RS11645	COG0596	Alpha beta hydrolase
NA29_RS11650	COG3473	Maleate cis-trans isomerase
NA29_RS11655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NA29_RS11660	COG2080	2 iron, 2 sulfur cluster binding
NA29_RS11665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NA29_RS11665	COG2010	Cytochrome c
NA29_RS11670	COG2271	Major facilitator Superfamily
NA29_RS11680	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
NA29_RS11680	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NA29_RS11695	COG0583	DNA-binding transcription factor activity
NA29_RS11715	COG0804	urea catabolic process
NA29_RS11735	COG0411	ABC transporter
NA29_RS11745	COG0683	leucine binding
NA29_RS11750	COG0477	Major facilitator Superfamily
NA29_RS11755	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NA29_RS11770	COG1012	belongs to the aldehyde dehydrogenase family
NA29_RS11780	COG0277	FAD linked oxidase domain protein
NA29_RS11785	COG4943	cyclic-guanylate-specific phosphodiesterase activity
NA29_RS11805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NA29_RS11815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NA29_RS11825	COG0179	Fumarylacetoacetate (FAA) hydrolase
NA29_RS11840	COG0154	amidase activity
NA29_RS11845	COG2814	Major facilitator Superfamily
NA29_RS11880	COG0657	acetylesterase activity
NA29_RS11885	COG2186	Transcriptional regulator
NA29_RS11890	COG0803	Belongs to the bacterial solute-binding protein 9 family
NA29_RS11895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NA29_RS11905	COG0477	Major facilitator Superfamily
NA29_RS11920	COG0668	transmembrane transport
NA29_RS11930	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS11935	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NA29_RS11970	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS11975	COG2188	Transcriptional regulator
NA29_RS12005	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NA29_RS12010	COG0066	3-isopropylmalate dehydratase activity
NA29_RS12025	COG1335	isochorismatase
NA29_RS12040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NA29_RS12045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NA29_RS12050	COG0477	Major facilitator Superfamily
NA29_RS12055	COG0235	Class ii aldolase
NA29_RS12060	COG1942	4-Oxalocrotonate Tautomerase
NA29_RS12080	COG0425	Belongs to the sulfur carrier protein TusA family
NA29_RS12085	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NA29_RS12090	COG0525	valine-tRNA ligase activity
NA29_RS12095	COG0210	DNA helicase
NA29_RS12105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NA29_RS12115	COG2391	methyltransferase activity
NA29_RS12120	COG1611	Belongs to the LOG family
NA29_RS12130	COG1252	NADH dehydrogenase
NA29_RS12135	COG0412	Dienelactone hydrolase
NA29_RS12160	COG1722	exodeoxyribonuclease VII activity
NA29_RS12165	COG0142	geranyltranstransferase activity
NA29_RS12170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NA29_RS12180	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NA29_RS12185	COG2081	HI0933 family
NA29_RS12190	COG1610	YqeY-like protein
NA29_RS12220	COG0583	DNA-binding transcription factor activity
NA29_RS12240	COG1595	DNA-templated transcription, initiation
NA29_RS12245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NA29_RS12250	COG0840	transmembrane signaling receptor activity
NA29_RS12260	COG0840	transmembrane signaling receptor activity
NA29_RS12265	COG0427	acetyl-CoA hydrolase
NA29_RS12280	COG4943	cyclic-guanylate-specific phosphodiesterase activity
NA29_RS12295	COG2814	Major facilitator Superfamily
NA29_RS12300	COG2814	Major facilitator Superfamily
NA29_RS12320	COG0747	negative chemotaxis
NA29_RS12330	COG0129	dihydroxy-acid dehydratase activity
NA29_RS12340	COG2271	Major facilitator Superfamily
NA29_RS12345	COG0583	DNA-binding transcription factor activity
NA29_RS12350	COG4221	oxidoreductase activity
NA29_RS12385	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NA29_RS12405	COG2814	Major facilitator Superfamily
NA29_RS12410	COG0583	DNA-binding transcription factor activity
NA29_RS12415	COG1929	Belongs to the glycerate kinase type-1 family
NA29_RS12435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NA29_RS12450	COG0583	DNA-binding transcription factor activity
NA29_RS12460	COG0842	Transport permease protein
NA29_RS12465	COG1131	(ABC) transporter
NA29_RS12475	COG0302	gtp cyclohydrolase
NA29_RS12485	COG1294	oxidase, subunit
NA29_RS12490	COG1271	oxidase subunit
NA29_RS12510	COG2223	nitrite transmembrane transporter activity
NA29_RS12525	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NA29_RS12530	COG3038	cytochrome b561
NA29_RS12545	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NA29_RS12585	COG0753	catalase activity
NA29_RS12595	COG0741	lytic transglycosylase activity
NA29_RS12615	COG1450	Type ii and iii secretion system protein
NA29_RS12645	COG1459	type II secretion system
NA29_RS12670	COG2124	cytochrome p450
NA29_RS12685	COG0583	DNA-binding transcription factor activity
NA29_RS12695	COG3842	ATPase activity
NA29_RS12735	COG4566	intracellular signal transduction
NA29_RS12745	COG3706	GGDEF domain
NA29_RS12805	COG4774	siderophore transport
NA29_RS12810	COG2366	antibiotic biosynthetic process
NA29_RS12815	COG1120	ATPase activity
NA29_RS12905	COG2176	DNA-directed DNA polymerase activity
NA29_RS12925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NA29_RS12935	COG2048	Heterodisulfide reductase, subunit B
NA29_RS13010	COG0446	pyridine nucleotide-disulphide oxidoreductase
NA29_RS13045	COG3473	Maleate cis-trans isomerase
NA29_RS13050	COG0596	Alpha beta hydrolase
NA29_RS13055	COG2309	aminopeptidase activity
NA29_RS13060	COG1335	isochorismatase
NA29_RS13065	COG0477	Major facilitator Superfamily
NA29_RS13070	COG1846	Transcriptional regulator
NA29_RS13080	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NA29_RS13090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NA29_RS13095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NA29_RS13100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NA29_RS13110	COG1561	YicC-like family, N-terminal region
NA29_RS13125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NA29_RS13135	COG1741	Belongs to the pirin family
NA29_RS13145	COG3118	belongs to the thioredoxin family
NA29_RS13170	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NA29_RS13175	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NA29_RS13185	COG2205	protein histidine kinase activity
NA29_RS13190	COG0745	RESPONSE REGULATOR receiver
NA29_RS13205	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NA29_RS13210	COG2346	COG2346, Truncated hemoglobins
NA29_RS13225	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NA29_RS13245	COG1309	transcriptional regulator
NA29_RS13290	COG0028	Belongs to the TPP enzyme family
NA29_RS13300	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NA29_RS13305	COG0688	phosphatidylethanolamine metabolic process
NA29_RS13310	COG1183	phosphatidylcholine synthase activity
NA29_RS13315	COG1652	LysM domain
NA29_RS13320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NA29_RS13340	COG1595	DNA-templated transcription, initiation
NA29_RS13350	COG0683	leucine binding
NA29_RS13355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NA29_RS13360	COG1185	polyribonucleotide nucleotidyltransferase activity
NA29_RS13405	COG0534	Mate efflux family protein
NA29_RS13415	COG0254	rRNA binding
NA29_RS13440	COG0277	FAD linked oxidase domain protein
NA29_RS13455	COG1295	ribonuclease BN
NA29_RS13465	COG0596	Alpha beta hydrolase
NA29_RS13480	COG0477	Major facilitator Superfamily
NA29_RS13500	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS13505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NA29_RS13515	COG2197	response regulator
NA29_RS13530	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS13540	COG0251	oxidation-reduction process
NA29_RS13545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NA29_RS13555	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NA29_RS13560	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NA29_RS13570	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NA29_RS13585	COG0776	regulation of translation
NA29_RS13595	COG3300	MHYT domain
NA29_RS13595	COG5001	Diguanylate cyclase
NA29_RS13610	COG1773	rubredoxin
NA29_RS13635	COG2200	EAL domain
NA29_RS13635	COG2202	Pas domain
NA29_RS13635	COG2199	diguanylate cyclase activity
NA29_RS13640	COG2501	S4 domain
NA29_RS13650	COG3706	GGDEF domain
NA29_RS13655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NA29_RS13680	COG3842	ATPase activity
NA29_RS13690	COG1177	transmembrane transport
NA29_RS13705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NA29_RS13715	COG2200	EAL domain
NA29_RS13725	COG5001	Diguanylate cyclase
NA29_RS13725	COG2203	Gaf domain
NA29_RS13725	COG3706	GGDEF domain
NA29_RS13725	COG4251	negative regulation of phosphorylation
NA29_RS13740	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NA29_RS13895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NA29_RS13925	COG1280	lysine exporter protein (LysE YggA)
NA29_RS13945	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NA29_RS13950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NA29_RS13955	COG0567	Dehydrogenase, E1 component
NA29_RS13960	COG0508	dehydrogenase complex catalyzes the overall conversion of
NA29_RS13965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NA29_RS13970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NA29_RS14045	COG4964	Belongs to the GSP D family
NA29_RS14095	COG3158	transport of potassium into the cell
NA29_RS14100	COG2183	response to ionizing radiation
NA29_RS14115	COG1199	ATP-dependent helicase activity
NA29_RS14120	COG0505	Belongs to the CarA family
NA29_RS14130	COG0564	pseudouridine synthase activity
NA29_RS14145	COG3243	poly(R)-hydroxyalkanoic acid synthase
NA29_RS14150	COG0183	Belongs to the thiolase family
NA29_RS14155	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS14165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NA29_RS14170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NA29_RS14175	COG0183	Belongs to the thiolase family
NA29_RS14180	COG0626	cystathionine gamma-synthase activity
NA29_RS14190	COG0560	Phosphoserine phosphatase
NA29_RS14235	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NA29_RS14240	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NA29_RS14245	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NA29_RS14250	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NA29_RS14255	COG0450	alkyl hydroperoxide reductase
NA29_RS14325	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NA29_RS14350	COG2814	Major facilitator Superfamily
NA29_RS14355	COG1741	Belongs to the pirin family
NA29_RS14375	COG0024	Methionine aminopeptidase
NA29_RS14410	COG0657	acetylesterase activity
NA29_RS14415	COG0583	DNA-binding transcription factor activity
NA29_RS14430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NA29_RS14430	COG1181	Belongs to the D-alanine--D-alanine ligase family
NA29_RS14440	COG1132	(ABC) transporter
NA29_RS14450	COG2974	May be involved in recombination
NA29_RS14465	COG0583	DNA-binding transcription factor activity
NA29_RS14470	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS14480	COG0850	regulation of cytokinetic process
NA29_RS14490	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NA29_RS14500	COG0318	PFAM AMP-dependent synthetase and ligase
NA29_RS14515	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS14520	COG1960	acyl-CoA dehydrogenase activity
NA29_RS14530	COG0544	peptidyl-prolyl cis-trans isomerase activity
NA29_RS14535	COG0740	serine-type endopeptidase activity
NA29_RS14545	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NA29_RS14565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NA29_RS14575	COG4181	ATPase activity
NA29_RS14580	COG0166	Belongs to the GPI family
NA29_RS14585	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NA29_RS14585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NA29_RS14590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NA29_RS14595	COG0047	phosphoribosylformylglycinamidine synthase activity
NA29_RS14595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NA29_RS14600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NA29_RS14610	COG2917	probably involved in intracellular septation
NA29_RS14620	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NA29_RS14625	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NA29_RS14630	COG0318	PFAM AMP-dependent synthetase and ligase
NA29_RS14645	COG0411	ABC transporter
NA29_RS14655	COG1024	Enoyl-CoA hydratase
NA29_RS14655	COG1250	3-hydroxyacyl-CoA dehydrogenase
NA29_RS14660	COG1335	isochorismatase
NA29_RS14670	COG2130	NADP-dependent
NA29_RS14690	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NA29_RS14705	COG0084	hydrolase, TatD family'
NA29_RS14715	COG1024	Enoyl-CoA hydratase
NA29_RS14720	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NA29_RS14725	COG1877	trehalose-phosphatase activity
NA29_RS14735	COG1254	Belongs to the acylphosphatase family
NA29_RS14740	COG0840	transmembrane signaling receptor activity
NA29_RS14750	COG1272	protein, Hemolysin III
NA29_RS14760	COG1522	sequence-specific DNA binding
NA29_RS14765	COG0028	Belongs to the TPP enzyme family
NA29_RS14775	COG0765	amino acid transport
NA29_RS14780	COG1126	abc transporter atp-binding protein
NA29_RS14820	COG0783	Belongs to the Dps family
NA29_RS14825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NA29_RS14825	COG1042	CoA-binding domain protein
NA29_RS14825	COG0045	succinate-CoA ligase (ADP-forming) activity
NA29_RS14830	COG0598	Magnesium transport protein CorA
NA29_RS14835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NA29_RS14840	COG0730	response to heat
NA29_RS14850	COG2197	response regulator
NA29_RS14855	COG2205	protein histidine kinase activity
NA29_RS14855	COG0784	Response regulator, receiver
NA29_RS14865	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NA29_RS14875	COG0628	permease
NA29_RS14890	COG1012	belongs to the aldehyde dehydrogenase family
NA29_RS14920	COG2226	methyltransferase
NA29_RS14950	COG1215	transferase activity, transferring glycosyl groups
NA29_RS14955	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NA29_RS14960	COG0457	Tetratricopeptide repeat
NA29_RS14980	COG0667	Aldo Keto reductase
NA29_RS15010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NA29_RS15015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NA29_RS15020	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS15045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NA29_RS15045	COG2755	lipolytic protein G-D-S-L family
NA29_RS15080	COG4106	trans-aconitate 2-methyltransferase activity
NA29_RS15085	COG0038	chloride channel
NA29_RS15090	COG2205	protein histidine kinase activity
NA29_RS15105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NA29_RS15110	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NA29_RS15115	COG4774	siderophore transport
NA29_RS15140	COG0583	DNA-binding transcription factor activity
NA29_RS15185	COG0583	DNA-binding transcription factor activity
NA29_RS15190	COG0596	Alpha beta hydrolase
NA29_RS15195	COG1309	transcriptional regulator
NA29_RS15205	COG0477	Major facilitator Superfamily
NA29_RS15230	COG0840	transmembrane signaling receptor activity
NA29_RS15235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NA29_RS15250	COG2204	response regulator
NA29_RS15260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NA29_RS15270	COG0154	amidase activity
NA29_RS15305	COG4774	siderophore transport
NA29_RS15315	COG1595	DNA-templated transcription, initiation
NA29_RS15320	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NA29_RS15325	COG1024	Enoyl-CoA hydratase
NA29_RS15330	COG1250	3-hydroxyacyl-CoA dehydrogenase
NA29_RS15335	COG3246	L-lysine catabolic process to acetate
NA29_RS15345	COG1022	Amp-dependent synthetase and ligase
NA29_RS15350	COG2814	Major facilitator Superfamily
NA29_RS15375	COG0583	DNA-binding transcription factor activity
NA29_RS15395	COG1953	Uracil, thiamine, allantoin
NA29_RS15410	COG2197	response regulator
NA29_RS15415	COG0402	S-adenosylhomocysteine deaminase activity
NA29_RS15430	COG0583	DNA-binding transcription factor activity
NA29_RS15435	COG3257	ureidoglycine aminohydrolase activity
NA29_RS15480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NA29_RS15490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NA29_RS15500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NA29_RS15515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NA29_RS15525	COG1113	amino acid transport
NA29_RS15550	COG3791	Glutathione-dependent formaldehyde-activating
NA29_RS15575	COG2207	Transcriptional regulator
NA29_RS15580	COG0300	oxidoreductase activity
NA29_RS15605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NA29_RS15620	COG0010	Belongs to the arginase family
NA29_RS15630	COG1113	amino acid transport
NA29_RS15635	COG2986	histidine ammonia-lyase
NA29_RS15650	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS15660	COG1176	ABC-type spermidine putrescine transport system, permease component I
NA29_RS15670	COG3842	ATPase activity
NA29_RS15690	COG0583	DNA-binding transcription factor activity
NA29_RS15695	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NA29_RS15700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NA29_RS15705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NA29_RS15730	COG0583	DNA-binding transcription factor activity
NA29_RS15740	COG1942	4-Oxalocrotonate Tautomerase
NA29_RS15755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NA29_RS15775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NA29_RS15780	COG0583	DNA-binding transcription factor activity
NA29_RS15790	COG0778	Nitroreductase
NA29_RS15810	COG2301	Belongs to the HpcH HpaI aldolase family
NA29_RS15815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NA29_RS15820	COG3493	citrate carrier protein
NA29_RS15825	COG0583	DNA-binding transcription factor activity
NA29_RS15840	COG1181	Belongs to the D-alanine--D-alanine ligase family
NA29_RS15845	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NA29_RS15855	COG1045	serine acetyltransferase
NA29_RS15860	COG0789	Transcriptional regulator
NA29_RS15880	COG1132	(ABC) transporter
NA29_RS15975	COG1335	isochorismatase
NA29_RS16000	COG2188	Transcriptional regulator
NA29_RS16010	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NA29_RS16030	COG0583	DNA-binding transcription factor activity
NA29_RS16035	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NA29_RS16050	COG1012	belongs to the aldehyde dehydrogenase family
NA29_RS16055	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS16070	COG0583	DNA-binding transcription factor activity
NA29_RS16085	COG0252	asparaginase activity
NA29_RS16095	COG0483	inositol monophosphate 1-phosphatase activity
NA29_RS16105	COG0579	oxidoreductase
NA29_RS16115	COG0640	Transcriptional regulator
NA29_RS16125	COG0165	Argininosuccinate lyase
NA29_RS16135	COG0583	DNA-binding transcription factor activity
NA29_RS16155	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NA29_RS16165	COG0589	response to stress
NA29_RS16170	COG2197	response regulator
NA29_RS16175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NA29_RS16200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NA29_RS16205	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NA29_RS16265	COG1309	transcriptional regulator
NA29_RS16270	COG0071	Belongs to the small heat shock protein (HSP20) family
NA29_RS16310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NA29_RS16355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NA29_RS16360	COG2271	Major facilitator Superfamily
NA29_RS16395	COG3040	lipid binding
NA29_RS16405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NA29_RS16425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NA29_RS16435	COG0625	glutathione transferase activity
NA29_RS16445	COG0640	Transcriptional regulator
NA29_RS16455	COG0798	PFAM Bile acid sodium symporter
NA29_RS16475	COG0596	Alpha beta hydrolase
NA29_RS16480	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NA29_RS16495	COG0372	Belongs to the citrate synthase family
NA29_RS16510	COG0446	pyridine nucleotide-disulphide oxidoreductase
NA29_RS16510	COG1902	pentaerythritol trinitrate reductase activity
NA29_RS16550	COG3119	arylsulfatase activity
NA29_RS16555	COG0583	DNA-binding transcription factor activity
NA29_RS16585	COG2837	iron assimilation
NA29_RS16600	COG1538	Outer membrane efflux protein
NA29_RS16640	COG1476	TRANSCRIPTIONal
NA29_RS16645	COG3550	peptidyl-serine autophosphorylation
NA29_RS16655	COG0534	Mate efflux family protein
NA29_RS16660	COG2814	Major facilitator Superfamily
NA29_RS16665	COG4572	Cation transport regulator
NA29_RS16675	COG2823	Periplasmic or secreted lipoprotein
NA29_RS16685	COG5001	Diguanylate cyclase
NA29_RS16685	COG3706	GGDEF domain
NA29_RS16685	COG2203	Gaf domain
NA29_RS16685	COG4251	negative regulation of phosphorylation
NA29_RS16695	COG3264	Mechanosensitive ion channel
NA29_RS16695	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NA29_RS16735	COG2070	2-Nitropropane dioxygenase
NA29_RS16745	COG0604	alcohol dehydrogenase
NA29_RS16750	COG0596	Alpha beta hydrolase
NA29_RS16780	COG1674	ftsk spoiiie
NA29_RS16790	COG5001	Diguanylate cyclase
NA29_RS16790	COG5002	protein histidine kinase activity
NA29_RS16805	COG2814	Major facilitator Superfamily
NA29_RS16810	COG3468	outer membrane autotransporter barrel domain protein
NA29_RS16815	COG3706	GGDEF domain
NA29_RS16825	COG0318	PFAM AMP-dependent synthetase and ligase
NA29_RS16830	COG1176	ABC-type spermidine putrescine transport system, permease component I
NA29_RS16835	COG3842	ATPase activity
NA29_RS16845	COG1024	Enoyl-CoA hydratase
NA29_RS16850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NA29_RS16855	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NA29_RS16860	COG0471	metal ion transport
NA29_RS16875	COG0733	neurotransmitter:sodium symporter activity
NA29_RS16900	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NA29_RS16905	COG3383	formate dehydrogenase (NAD+) activity
NA29_RS16925	COG0243	molybdopterin cofactor binding
NA29_RS16955	COG4774	siderophore transport
NA29_RS16965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NA29_RS16990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NA29_RS17010	COG0789	Transcriptional regulator
NA29_RS17015	COG0446	pyridine nucleotide-disulphide oxidoreductase
NA29_RS17025	COG3706	GGDEF domain
NA29_RS17050	COG0488	(ABC) transporter
NA29_RS17060	COG1079	Belongs to the binding-protein-dependent transport system permease family
NA29_RS17065	COG4603	Belongs to the binding-protein-dependent transport system permease family
NA29_RS17070	COG3845	ABC transporter
NA29_RS17075	COG0583	DNA-binding transcription factor activity
NA29_RS17085	COG2233	PERMEase
NA29_RS17120	COG2308	Evidence 4 Homologs of previously reported genes of
NA29_RS17130	COG4266	Belongs to the allantoicase family
NA29_RS17135	COG3648	Uricase
NA29_RS17135	COG3195	allantoin biosynthetic process
NA29_RS17145	COG1619	proteins homologs of microcin C7 resistance protein MccF
NA29_RS17165	COG0559	Belongs to the binding-protein-dependent transport system permease family
NA29_RS17175	COG1126	abc transporter atp-binding protein
NA29_RS17180	COG0410	ABC transporter
NA29_RS17195	COG0583	DNA-binding transcription factor activity
NA29_RS17225	COG1289	transmembrane transporter activity
NA29_RS17235	COG0583	DNA-binding transcription factor activity
NA29_RS17240	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS17250	COG0583	DNA-binding transcription factor activity
NA29_RS17265	COG2197	response regulator
NA29_RS17270	COG4585	Histidine kinase
NA29_RS17275	COG0519	Catalyzes the synthesis of GMP from XMP
NA29_RS17275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NA29_RS17295	COG2914	Belongs to the UPF0125 (RnfH) family
NA29_RS17300	COG2867	negative regulation of translational initiation
NA29_RS17305	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NA29_RS17310	COG0330	HflC and HflK could
NA29_RS17325	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NA29_RS17330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NA29_RS17355	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NA29_RS17370	COG0750	zinc metalloprotease
NA29_RS17375	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NA29_RS17385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NA29_RS17400	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NA29_RS17405	COG0052	Belongs to the universal ribosomal protein uS2 family
NA29_RS17415	COG0024	Methionine aminopeptidase
NA29_RS17425	COG1187	pseudouridine synthase activity
NA29_RS17430	COG0242	peptide deformylase activity
NA29_RS17435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NA29_RS17460	COG2171	N-acyltransferase activity
NA29_RS17465	COG1393	Belongs to the ArsC family
NA29_RS17470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NA29_RS17475	COG2890	protein-(glutamine-N5) methyltransferase activity
NA29_RS17480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NA29_RS17485	COG0488	(ABC) transporter
NA29_RS17505	COG0477	Major facilitator Superfamily
NA29_RS17510	COG0351	phosphomethylpyrimidine kinase
NA29_RS17520	COG1573	uracil-dna glycosylase
NA29_RS17530	COG1214	PFAM Peptidase M22, glycoprotease
NA29_RS17535	COG0513	Belongs to the DEAD box helicase family
NA29_RS17545	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NA29_RS17550	COG0583	DNA-binding transcription factor activity
NA29_RS17560	COG2224	Isocitrate lyase
NA29_RS17595	COG3275	phosphorelay sensor kinase activity
NA29_RS17605	COG0542	response to heat
NA29_RS17615	COG0314	molybdopterin synthase activity
NA29_RS17620	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NA29_RS17640	COG0436	Aminotransferase
NA29_RS17650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NA29_RS17655	COG2076	Multidrug Resistance protein
NA29_RS17660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NA29_RS17680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NA29_RS17685	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NA29_RS17690	COG0791	NLP P60 protein
NA29_RS17700	COG0306	phosphate transporter
NA29_RS17715	COG0359	binds to the 23S rRNA
NA29_RS17730	COG0360	Binds together with S18 to 16S ribosomal RNA
NA29_RS17735	COG0583	DNA-binding transcription factor activity
NA29_RS17740	COG3960	tartronate-semialdehyde synthase activity
NA29_RS17745	COG3622	Belongs to the hyi family
NA29_RS17750	COG2084	Dehydrogenase
NA29_RS17755	COG0252	asparaginase activity
NA29_RS17760	COG0583	DNA-binding transcription factor activity
NA29_RS17765	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NA29_RS17770	COG4208	sulfate ABC transporter
NA29_RS17775	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NA29_RS17780	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NA29_RS17790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NA29_RS17805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NA29_RS17810	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NA29_RS17850	COG1566	PFAM secretion protein HlyD family protein
NA29_RS17855	COG2814	Major facilitator Superfamily
NA29_RS17880	COG1278	Cold shock
NA29_RS17885	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NA29_RS17890	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NA29_RS17895	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NA29_RS17900	COG0195	Participates in both transcription termination and antitermination
NA29_RS17900	COG2251	uridine kinase activity
NA29_RS17905	COG0779	Required for maturation of 30S ribosomal subunits
NA29_RS17915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NA29_RS17920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NA29_RS17930	COG0583	DNA-binding transcription factor activity
NA29_RS17940	COG1058	Belongs to the CinA family
NA29_RS17940	COG1546	Belongs to the CinA family
NA29_RS17955	COG1643	Atp-dependent helicase
NA29_RS17960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NA29_RS17960	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NA29_RS17975	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NA29_RS17995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NA29_RS18000	COG0557	exoribonuclease II activity
NA29_RS18020	COG0583	DNA-binding transcription factor activity
NA29_RS18035	COG2207	Transcriptional regulator
NA29_RS18050	COG1116	anion transmembrane transporter activity
NA29_RS18055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NA29_RS18060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NA29_RS18065	COG1187	pseudouridine synthase activity
NA29_RS18070	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NA29_RS18075	COG2818	Glycosylase
NA29_RS18080	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS18090	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS18095	COG2186	Transcriptional regulator
NA29_RS18100	COG0387	Pfam Sodium calcium exchanger
NA29_RS18115	COG0307	riboflavin synthase, alpha
NA29_RS18150	COG0174	glutamine synthetase
NA29_RS18160	COG1280	lysine exporter protein (LysE YggA)
NA29_RS18215	COG0840	transmembrane signaling receptor activity
NA29_RS18220	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NA29_RS18225	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NA29_RS18230	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NA29_RS18270	COG0679	Auxin Efflux Carrier
NA29_RS18280	COG1278	Cold shock
NA29_RS18285	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NA29_RS18305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NA29_RS18350	COG1278	Cold shock
NA29_RS18365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NA29_RS18390	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NA29_RS18395	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NA29_RS18400	COG0167	dihydroorotate dehydrogenase activity
NA29_RS18405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NA29_RS18410	COG0765	amino acid transport
NA29_RS18415	COG1139	Iron-sulfur cluster binding protein
NA29_RS18430	COG1414	Transcriptional regulator
NA29_RS18445	COG0697	spore germination
NA29_RS18450	COG0123	including yeast histone deacetylase and acetoin utilization protein
NA29_RS18460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NA29_RS18470	COG0508	dehydrogenase complex catalyzes the overall conversion of
NA29_RS18475	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NA29_RS18490	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NA29_RS18495	COG0339	signal peptide processing
NA29_RS18505	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NA29_RS18510	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NA29_RS18515	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NA29_RS18520	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
NA29_RS18525	COG0330	HflC and HflK could
NA29_RS18530	COG0330	HflC and HflK could
NA29_RS18535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NA29_RS18540	COG1923	regulation of RNA biosynthetic process
NA29_RS18545	COG1160	GTP binding
NA29_RS18555	COG2976	Protein conserved in bacteria
NA29_RS18560	COG0124	histidyl-tRNA synthetase
NA29_RS18565	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NA29_RS18575	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NA29_RS18580	COG0105	UTP biosynthetic process
NA29_RS18615	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NA29_RS18620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NA29_RS18635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NA29_RS18640	COG2197	response regulator
NA29_RS18685	COG2204	response regulator
NA29_RS18695	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NA29_RS18710	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NA29_RS18720	COG1840	ABC-type Fe3 transport system, periplasmic component
NA29_RS18725	COG1752	Esterase of the alpha-beta hydrolase superfamily
NA29_RS18730	COG0791	NLP P60 protein
NA29_RS18735	COG4172	Belongs to the ABC transporter superfamily
NA29_RS18740	COG4239	(ABC) transporter, permease
NA29_RS18745	COG4174	ABC transporter (Permease)
NA29_RS18750	COG4166	transmembrane transport
NA29_RS18775	COG0527	aspartate kinase activity
NA29_RS18780	COG0037	tRNA processing
NA29_RS18790	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NA29_RS18805	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NA29_RS18820	COG1045	serine acetyltransferase
NA29_RS18830	COG0483	inositol monophosphate 1-phosphatase activity
NA29_RS18835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NA29_RS18845	COG1116	anion transmembrane transporter activity
NA29_RS18850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NA29_RS18855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NA29_RS18860	COG0431	NADPH-dependent FMN reductase
NA29_RS18870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NA29_RS18870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NA29_RS18875	COG2194	sulfuric ester hydrolase activity
NA29_RS18885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NA29_RS18910	COG0285	dihydrofolate synthase activity
NA29_RS18915	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NA29_RS18920	COG0159	tryptophan synthase activity
NA29_RS18930	COG0133	tryptophan synthase activity
NA29_RS18935	COG0135	phosphoribosylanthranilate isomerase activity
NA29_RS18950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NA29_RS18955	COG0473	3-isopropylmalate dehydrogenase activity
NA29_RS18960	COG0066	3-isopropylmalate dehydratase activity
NA29_RS18970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NA29_RS18975	COG0372	Belongs to the citrate synthase family
NA29_RS18980	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NA29_RS18985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NA29_RS18990	COG1053	succinate dehydrogenase
NA29_RS19005	COG2188	Transcriptional regulator
NA29_RS19010	COG0039	L-malate dehydrogenase activity
NA29_RS19020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NA29_RS19055	COG2866	Carboxypeptidase
NA29_RS19060	COG3022	response to hydroperoxide
NA29_RS19070	COG0436	Aminotransferase
NA29_RS19075	COG0625	glutathione transferase activity
NA29_RS19080	COG1250	3-hydroxyacyl-CoA dehydrogenase
NA29_RS19085	COG1024	Enoyl-CoA hydratase
NA29_RS19100	COG1960	acyl-CoA dehydrogenase activity
NA29_RS19105	COG0625	glutathione transferase activity
NA29_RS19160	COG1007	ATP synthesis coupled electron transport
NA29_RS19175	COG0713	ATP synthesis coupled electron transport
NA29_RS19185	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NA29_RS19190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NA29_RS19195	COG1034	ATP synthesis coupled electron transport
NA29_RS19205	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NA29_RS19210	COG0649	NAD binding
NA29_RS19225	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NA29_RS19240	COG0149	triose-phosphate isomerase activity
NA29_RS19255	COG5002	protein histidine kinase activity
NA29_RS19255	COG3447	MASE1 domain protein
NA29_RS19255	COG5001	Diguanylate cyclase
NA29_RS19280	COG2850	peptidyl-arginine hydroxylation
NA29_RS19290	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NA29_RS19295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NA29_RS19300	COG2226	methyltransferase
NA29_RS19305	COG0180	Tryptophanyl-tRNA synthetase
NA29_RS19310	COG1994	Peptidase M50
NA29_RS19315	COG0009	L-threonylcarbamoyladenylate synthase
NA29_RS19320	COG0613	PHP domain protein
NA29_RS19325	COG2267	carboxylic ester hydrolase activity
NA29_RS19330	COG2833	Protein of unknown function (DUF455)
NA29_RS19340	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NA29_RS19350	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NA29_RS19355	COG0148	phosphopyruvate hydratase activity
NA29_RS19360	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NA29_RS19365	COG0504	CTP synthase activity
NA29_RS19370	COG2267	carboxylic ester hydrolase activity
NA29_RS19380	COG0084	hydrolase, TatD family'
NA29_RS19400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NA29_RS19435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NA29_RS19445	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NA29_RS19485	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NA29_RS19490	COG0316	Belongs to the HesB IscA family
NA29_RS19495	COG0822	iron-sulfur transferase activity
NA29_RS19500	COG1104	cysteine desulfurase activity
NA29_RS19515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NA29_RS19520	COG0556	nucleotide-excision repair
NA29_RS19535	COG1309	transcriptional regulator
NA29_RS19540	COG2878	Part of a membrane complex involved in electron transport
NA29_RS19545	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NA29_RS19550	COG0778	Nitroreductase
NA29_RS19555	COG0697	spore germination
NA29_RS19575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NA29_RS19585	COG3135	benzoate transporter
NA29_RS19630	COG0697	spore germination
NA29_RS19635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NA29_RS19645	COG2814	Major facilitator Superfamily
NA29_RS19650	COG0583	DNA-binding transcription factor activity
NA29_RS19665	COG0741	lytic transglycosylase activity
NA29_RS19680	COG0488	(ABC) transporter
NA29_RS19685	COG2153	protein acetylation
NA29_RS19705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NA29_RS19715	COG0415	Belongs to the DNA photolyase family
NA29_RS19725	COG1285	pathogenesis
NA29_RS19730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NA29_RS19740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NA29_RS19745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NA29_RS19755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NA29_RS19760	COG0583	DNA-binding transcription factor activity
NA29_RS19765	COG1178	ABC-type Fe3 transport system permease component
NA29_RS19770	COG3842	ATPase activity
NA29_RS19775	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NA29_RS19785	COG5001	Diguanylate cyclase
NA29_RS19785	COG2203	Gaf domain
NA29_RS19785	COG3706	GGDEF domain
NA29_RS19785	COG4251	negative regulation of phosphorylation
NA29_RS19805	COG0559	Belongs to the binding-protein-dependent transport system permease family
NA29_RS19815	COG0312	modulator of DNA gyrase
NA29_RS19825	COG0521	Mo-molybdopterin cofactor biosynthetic process
NA29_RS19830	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NA29_RS19835	COG0501	Belongs to the peptidase M48B family
NA29_RS19840	COG1162	GTPase activity
NA29_RS19850	COG0494	nUDIX hydrolase
NA29_RS19855	COG0335	large ribosomal subunit rRNA binding
NA29_RS19860	COG0336	Belongs to the RNA methyltransferase TrmD family
NA29_RS19865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NA29_RS19870	COG0228	four-way junction DNA binding
NA29_RS19905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NA29_RS19910	COG0686	Belongs to the AlaDH PNT family
NA29_RS19915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NA29_RS19940	COG0583	DNA-binding transcription factor activity
NA29_RS19990	COG2814	Major facilitator Superfamily
NA29_RS19995	COG0543	2 iron, 2 sulfur cluster binding
NA29_RS20030	COG2808	Putative FMN-binding domain
NA29_RS20070	COG1414	Transcriptional regulator
NA29_RS20075	COG2084	Dehydrogenase
NA29_RS20080	COG0824	Thioesterase
NA29_RS20090	COG0848	biopolymer transport protein
NA29_RS20100	COG0823	Involved in the tonB-independent uptake of proteins
NA29_RS20135	COG0583	DNA-binding transcription factor activity
NA29_RS20155	COG0583	DNA-binding transcription factor activity
NA29_RS20185	COG0483	inositol monophosphate 1-phosphatase activity
NA29_RS20195	COG1609	Transcriptional regulator
NA29_RS20200	COG0395	ABC-type sugar transport system, permease component
NA29_RS20205	COG1175	transmembrane transport
NA29_RS20210	COG1653	transport
NA29_RS20240	COG2814	Major facilitator Superfamily
NA29_RS20250	COG1522	sequence-specific DNA binding
NA29_RS20255	COG1349	DNA-binding transcription factor activity
NA29_RS20265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS20270	COG2207	Transcriptional regulator
NA29_RS20280	COG1959	2 iron, 2 sulfur cluster binding
NA29_RS20300	COG1595	DNA-templated transcription, initiation
NA29_RS20305	COG3712	iron ion homeostasis
NA29_RS20310	COG4774	siderophore transport
NA29_RS20335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NA29_RS20350	COG1120	ATPase activity
NA29_RS20380	COG1301	dicarboxylic acid transport
NA29_RS20385	COG1802	Transcriptional regulator
NA29_RS20390	COG0596	Alpha beta hydrolase
NA29_RS20405	COG0583	DNA-binding transcription factor activity
NA29_RS20415	COG3276	selenocysteine insertion sequence binding
NA29_RS20430	COG2864	formate dehydrogenase
NA29_RS20435	COG0437	4 iron, 4 sulfur cluster binding
NA29_RS20440	COG0243	molybdopterin cofactor binding
NA29_RS20440	COG3383	formate dehydrogenase (NAD+) activity
NA29_RS20445	COG3383	formate dehydrogenase (NAD+) activity
NA29_RS20445	COG0243	molybdopterin cofactor binding
NA29_RS20455	COG2995	paraquat-inducible protein a
NA29_RS20460	COG3008	intermembrane lipid transfer
NA29_RS20470	COG1280	lysine exporter protein (LysE YggA)
NA29_RS20480	COG0477	Major facilitator Superfamily
NA29_RS20500	COG3387	PFAM Glycoside hydrolase 15-related
NA29_RS20505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NA29_RS20510	COG1024	Enoyl-CoA hydratase
NA29_RS20520	COG1802	Transcriptional regulator
NA29_RS20535	COG0583	DNA-binding transcription factor activity
NA29_RS20575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NA29_RS20580	COG4191	Histidine kinase
NA29_RS20600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NA29_RS20605	COG1802	Transcriptional regulator
NA29_RS20610	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NA29_RS20620	COG3383	formate dehydrogenase (NAD+) activity
NA29_RS20655	COG2985	domain, Protein
NA29_RS20660	COG2985	domain, Protein
NA29_RS20670	COG0534	Mate efflux family protein
NA29_RS20690	COG0589	response to stress
NA29_RS20700	COG1175	transmembrane transport
NA29_RS20705	COG1653	transport
NA29_RS20710	COG3842	ATPase activity
NA29_RS20735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NA29_RS20745	COG0747	negative chemotaxis
NA29_RS20750	COG4172	Belongs to the ABC transporter superfamily
NA29_RS20755	COG1446	asparaginase
NA29_RS20775	COG1024	Enoyl-CoA hydratase
NA29_RS20780	COG1960	acyl-CoA dehydrogenase activity
NA29_RS20785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NA29_RS20800	COG2271	Major facilitator Superfamily
NA29_RS20805	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS20810	COG1414	Transcriptional regulator
NA29_RS20835	COG2814	Major facilitator Superfamily
NA29_RS20845	COG0277	FAD linked oxidase domain protein
NA29_RS20850	COG2186	Transcriptional regulator
NA29_RS20860	COG0004	ammonium transporteR
NA29_RS20915	COG1414	Transcriptional regulator
NA29_RS20920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NA29_RS20925	COG4569	acetaldehyde dehydrogenase (acetylating) activity
NA29_RS20950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NA29_RS20955	COG1695	Transcriptional regulator
NA29_RS20960	COG2375	cellular response to nickel ion
NA29_RS20970	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS20985	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NA29_RS20995	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
NA29_RS20995	COG0028	Belongs to the TPP enzyme family
NA29_RS21000	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NA29_RS21005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NA29_RS21030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NA29_RS21035	COG0463	Glycosyl transferase, family 2
NA29_RS21045	COG1657	PFAM Prenyltransferase squalene oxidase
NA29_RS21050	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NA29_RS21055	COG1562	ergosterol biosynthetic process
NA29_RS21070	COG2070	2-Nitropropane dioxygenase
NA29_RS21090	COG1845	cytochrome c oxidase, subunit III
NA29_RS21095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NA29_RS21100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NA29_RS21110	COG0745	RESPONSE REGULATOR receiver
NA29_RS21115	COG5002	protein histidine kinase activity
NA29_RS21120	COG0488	(ABC) transporter
NA29_RS21130	COG0583	DNA-binding transcription factor activity
NA29_RS21145	COG0662	Cupin 2, conserved barrel domain protein
NA29_RS21155	COG1538	Outer membrane efflux protein
NA29_RS21165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NA29_RS21170	COG2860	membrane
NA29_RS21185	COG2271	Major facilitator Superfamily
NA29_RS21195	COG0235	Class ii aldolase
NA29_RS21210	COG2031	fatty acid transporter
NA29_RS21215	COG2423	ornithine cyclodeaminase activity
NA29_RS21220	COG0243	molybdopterin cofactor binding
NA29_RS21230	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NA29_RS21235	COG3395	kinase activity
NA29_RS21245	COG1349	DNA-binding transcription factor activity
NA29_RS21255	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NA29_RS21265	COG3485	protocatechuate 3,4-dioxygenase
NA29_RS21290	COG1794	racemase activity, acting on amino acids and derivatives
NA29_RS21310	COG4221	oxidoreductase activity
NA29_RS21345	COG4948	Mandelate Racemase Muconate Lactonizing
NA29_RS21360	COG4771	TonB-dependent receptor
NA29_RS21375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NA29_RS21395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NA29_RS21400	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NA29_RS21405	COG4521	taurine ABC transporter
NA29_RS21415	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NA29_RS21440	COG2159	amidohydrolase
NA29_RS21450	COG3384	dioxygenase
NA29_RS21455	COG4638	Rieske (2fe-2S)
NA29_RS21460	COG0523	cobalamin synthesis protein
NA29_RS21470	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NA29_RS21475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NA29_RS21475	COG0473	3-isopropylmalate dehydrogenase activity
NA29_RS21480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NA29_RS21485	COG3384	dioxygenase
NA29_RS21520	COG1309	transcriptional regulator
NA29_RS21525	COG0235	Class ii aldolase
NA29_RS21545	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NA29_RS21550	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NA29_RS21555	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NA29_RS21560	COG1674	ftsk spoiiie
NA29_RS21565	COG0492	ferredoxin-NADP+ reductase activity
NA29_RS21570	COG1193	negative regulation of DNA recombination
NA29_RS21575	COG2860	membrane
NA29_RS21595	COG2249	NAD(P)H dehydrogenase (quinone) activity
NA29_RS21605	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NA29_RS21620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NA29_RS21640	COG0277	FAD linked oxidase domain protein
NA29_RS21655	COG2271	Major facilitator Superfamily
NA29_RS21660	COG0477	Major facilitator Superfamily
NA29_RS21675	COG0181	hydroxymethylbilane synthase activity
NA29_RS21690	COG0165	Argininosuccinate lyase
NA29_RS21695	COG0786	glutamate:sodium symporter activity
NA29_RS21705	COG0717	Belongs to the dCTP deaminase family
NA29_RS21710	COG0489	protein tyrosine kinase activity
NA29_RS21715	COG2885	chlorophyll binding
NA29_RS21725	COG1522	sequence-specific DNA binding
NA29_RS21740	COG2911	Protein conserved in bacteria
NA29_RS21760	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NA29_RS21765	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NA29_RS21770	COG0489	protein tyrosine kinase activity
NA29_RS21775	COG1492	cobalamin metabolic process
NA29_RS21800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NA29_RS21810	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NA29_RS21815	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NA29_RS21825	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NA29_RS21830	COG4139	cobalamin transport
NA29_RS21835	COG4206	TonB-dependent receptor
NA29_RS21850	COG1960	acyl-CoA dehydrogenase activity
NA29_RS21865	COG0596	Alpha beta hydrolase
NA29_RS21875	COG1024	Enoyl-CoA hydratase
NA29_RS21880	COG0123	including yeast histone deacetylase and acetoin utilization protein
NA29_RS21885	COG2951	lytic endotransglycosylase activity
NA29_RS21905	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NA29_RS21915	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NA29_RS21935	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NA29_RS21940	COG1914	H( )-stimulated, divalent metal cation uptake system
NA29_RS21945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NA29_RS21950	COG0287	Prephenate dehydrogenase
NA29_RS21960	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NA29_RS21995	COG0318	PFAM AMP-dependent synthetase and ligase
NA29_RS22000	COG1024	Enoyl-CoA hydratase
NA29_RS22020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NA29_RS22025	COG1802	Transcriptional regulator
NA29_RS22030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NA29_RS22035	COG0583	DNA-binding transcription factor activity
NA29_RS22040	COG0129	dihydroxy-acid dehydratase activity
NA29_RS22065	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NA29_RS22070	COG0795	lipopolysaccharide-transporting ATPase activity
NA29_RS22110	COG2895	sulfate adenylyltransferase (ATP) activity
NA29_RS22120	COG0175	sulfate reduction
NA29_RS22125	COG0730	response to heat
NA29_RS22130	COG0583	DNA-binding transcription factor activity
NA29_RS22215	COG3609	addiction module antidote protein, CC2985 family
NA29_RS22240	COG2072	flavoprotein involved in K transport
NA29_RS22275	COG4638	Rieske (2fe-2S)
NA29_RS22280	COG2207	Transcriptional regulator
NA29_RS22285	COG0386	Belongs to the glutathione peroxidase family
NA29_RS22320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NA29_RS22325	COG1012	belongs to the aldehyde dehydrogenase family
NA29_RS22335	COG0028	Belongs to the TPP enzyme family
NA29_RS22345	COG1414	Transcriptional regulator
NA29_RS22350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NA29_RS22365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NA29_RS22370	COG1116	anion transmembrane transporter activity
NA29_RS22380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NA29_RS22395	COG0640	Transcriptional regulator
NA29_RS22405	COG2814	Major facilitator Superfamily
NA29_RS22410	COG0443	Heat shock 70 kDa protein
NA29_RS22420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NA29_RS22425	COG3360	Dodecin
NA29_RS22430	COG1846	Transcriptional regulator
NA29_RS22435	COG0837	glucose binding
NA29_RS22435	COG1737	Transcriptional regulator
NA29_RS22445	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NA29_RS22460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NA29_RS22475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NA29_RS22485	COG0671	phosphoesterase, PA-phosphatase related
NA29_RS22490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NA29_RS22495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NA29_RS22500	COG1704	LemA family
NA29_RS22515	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NA29_RS22515	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NA29_RS22525	COG3971	2-oxopent-4-enoate hydratase activity
NA29_RS22570	COG0640	Transcriptional regulator
NA29_RS22580	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NA29_RS22585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NA29_RS22590	COG0436	Aminotransferase
NA29_RS22595	COG0741	lytic transglycosylase activity
NA29_RS22610	COG0531	amino acid
NA29_RS22615	COG5001	Diguanylate cyclase
NA29_RS22615	COG3300	MHYT domain
NA29_RS22625	COG2011	ABC-type metal ion transport system permease component
NA29_RS22630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NA29_RS22660	COG4585	Histidine kinase
NA29_RS22665	COG3237	CsbD-like
NA29_RS22685	COG0840	transmembrane signaling receptor activity
NA29_RS22720	COG0745	RESPONSE REGULATOR receiver
NA29_RS22725	COG2205	protein histidine kinase activity
NA29_RS22730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS22735	COG3842	ATPase activity
NA29_RS22740	COG1840	ABC-type Fe3 transport system, periplasmic component
NA29_RS22745	COG4149	molybdate abc transporter
NA29_RS22750	COG2271	Major facilitator Superfamily
NA29_RS22755	COG0318	PFAM AMP-dependent synthetase and ligase
NA29_RS22760	COG1012	belongs to the aldehyde dehydrogenase family
NA29_RS22765	COG1414	Transcriptional regulator
NA29_RS22790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NA29_RS22795	COG0583	DNA-binding transcription factor activity
NA29_RS22800	COG3284	Transcriptional regulator
NA29_RS22805	COG0667	Aldo Keto reductase
NA29_RS22815	COG3634	alkyl hydroperoxide reductase activity
NA29_RS22835	COG0513	Belongs to the DEAD box helicase family
NA29_RS22850	COG1288	antiporter activity
NA29_RS22865	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS22890	COG2814	Major facilitator Superfamily
NA29_RS22905	COG1917	Cupin 2, conserved barrel domain protein
NA29_RS22905	COG2207	Transcriptional regulator
NA29_RS22910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NA29_RS22915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NA29_RS22925	COG3485	protocatechuate 3,4-dioxygenase
NA29_RS22930	COG3485	protocatechuate 3,4-dioxygenase
NA29_RS22935	COG0583	DNA-binding transcription factor activity
NA29_RS22945	COG1960	acyl-CoA dehydrogenase activity
NA29_RS22950	COG0318	PFAM AMP-dependent synthetase and ligase
NA29_RS22955	COG1012	belongs to the aldehyde dehydrogenase family
NA29_RS22960	COG1024	Enoyl-CoA hydratase
NA29_RS22965	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS22970	COG2814	Major facilitator Superfamily
NA29_RS22980	COG0745	RESPONSE REGULATOR receiver
NA29_RS22995	COG0840	transmembrane signaling receptor activity
NA29_RS23000	COG0643	Histidine kinase
NA29_RS23000	COG2198	Histidine kinase
NA29_RS23005	COG0583	DNA-binding transcription factor activity
NA29_RS23015	COG2814	Major facilitator Superfamily
NA29_RS23025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NA29_RS23030	COG0601	transmembrane transport
NA29_RS23040	COG4608	Belongs to the ABC transporter superfamily
NA29_RS23045	COG0444	Belongs to the ABC transporter superfamily
NA29_RS23055	COG0477	Major facilitator Superfamily
NA29_RS23060	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NA29_RS23065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NA29_RS23070	COG1845	cytochrome c oxidase, subunit III
NA29_RS23075	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NA29_RS23100	COG2011	ABC-type metal ion transport system permease component
NA29_RS23105	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NA29_RS23110	COG1464	Belongs to the NlpA lipoprotein family
NA29_RS23115	COG1686	Belongs to the peptidase S11 family
NA29_RS23120	COG0477	Major facilitator Superfamily
NA29_RS23125	COG1297	OPT oligopeptide transporter protein
NA29_RS23160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NA29_RS23165	COG1988	membrane-bound metal-dependent
NA29_RS23230	COG2824	Alkylphosphonate utilization operon protein PhnA
NA29_RS23245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NA29_RS23245	COG1116	anion transmembrane transporter activity
NA29_RS23260	COG0243	molybdopterin cofactor binding
NA29_RS23270	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NA29_RS23310	COG1960	acyl-CoA dehydrogenase activity
NA29_RS23345	COG2197	response regulator
NA29_RS23350	COG0583	DNA-binding transcription factor activity
NA29_RS23375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NA29_RS23410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NA29_RS23420	COG0436	Aminotransferase
NA29_RS23450	COG0183	Belongs to the thiolase family
NA29_RS23455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NA29_RS23465	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS23470	COG0583	DNA-binding transcription factor activity
NA29_RS23475	COG3284	Transcriptional regulator
NA29_RS23480	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS23485	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NA29_RS23500	COG1803	Methylglyoxal synthase
NA29_RS23505	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS23510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NA29_RS23520	COG0433	COG0433 Predicted ATPase
NA29_RS23525	COG0217	transcriptional regulatory protein
NA29_RS23530	COG0151	Belongs to the GarS family
NA29_RS23535	COG0668	transmembrane transport
NA29_RS23540	COG0408	coproporphyrinogen oxidase activity
NA29_RS23550	COG0799	negative regulation of ribosome biogenesis
NA29_RS23555	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NA29_RS23560	COG1653	transport
NA29_RS23570	COG0395	ABC-type sugar transport system, permease component
NA29_RS23580	COG0584	glycerophosphoryl diester phosphodiesterase
NA29_RS23585	COG0424	maF-like protein
NA29_RS23590	COG1530	ribonuclease E activity
NA29_RS23595	COG0840	transmembrane signaling receptor activity
NA29_RS23600	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NA29_RS23650	COG1054	Belongs to the UPF0176 family
NA29_RS23655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NA29_RS23660	COG0513	Belongs to the DEAD box helicase family
NA29_RS23670	COG0583	DNA-binding transcription factor activity
NA29_RS23680	COG0655	NAD(P)H dehydrogenase (quinone) activity
NA29_RS23695	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NA29_RS23705	COG1253	flavin adenine dinucleotide binding
NA29_RS23710	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NA29_RS23715	COG1074	ATP-dependent DNA helicase activity
NA29_RS23720	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NA29_RS23725	COG1289	transmembrane transporter activity
NA29_RS23730	COG2197	response regulator
NA29_RS23740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NA29_RS23745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NA29_RS23775	COG0477	Major facilitator Superfamily
NA29_RS23790	COG0640	Transcriptional regulator
NA29_RS23800	COG0583	DNA-binding transcription factor activity
NA29_RS23815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NA29_RS23820	COG0765	amino acid transport
NA29_RS23825	COG0765	amino acid transport
NA29_RS23845	COG1917	Cupin 2, conserved barrel domain protein
NA29_RS23845	COG2207	Transcriptional regulator
NA29_RS23850	COG0346	lactoylglutathione lyase activity
NA29_RS23860	COG0583	DNA-binding transcription factor activity
NA29_RS23870	COG0066	3-isopropylmalate dehydratase activity
NA29_RS23875	COG3493	citrate carrier protein
NA29_RS23905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NA29_RS23925	COG0543	2 iron, 2 sulfur cluster binding
NA29_RS23925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NA29_RS23930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NA29_RS23950	COG0411	ABC transporter
NA29_RS23970	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NA29_RS23975	COG1047	Peptidyl-prolyl cis-trans
NA29_RS23980	COG2003	Belongs to the UPF0758 family
NA29_RS23985	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NA29_RS23995	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NA29_RS24005	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NA29_RS24015	COG3264	Mechanosensitive ion channel
NA29_RS24015	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NA29_RS24020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NA29_RS24020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NA29_RS24025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NA29_RS24030	COG0196	riboflavin kinase activity
NA29_RS24035	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NA29_RS24040	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NA29_RS24045	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NA29_RS24050	COG2814	Major facilitator Superfamily
NA29_RS24055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NA29_RS24065	COG0542	response to heat
NA29_RS24070	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NA29_RS24075	COG1278	Cold shock
NA29_RS24110	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS24115	COG0583	DNA-binding transcription factor activity
NA29_RS24165	COG3437	response regulator, receiver
NA29_RS24165	COG0784	Response regulator, receiver
NA29_RS24170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NA29_RS24175	COG1570	exodeoxyribonuclease VII activity
NA29_RS24180	COG0811	peptide transport
NA29_RS24195	COG2835	tetraacyldisaccharide 4'-kinase activity
NA29_RS24200	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NA29_RS24205	COG0563	adenylate kinase activity
NA29_RS24220	COG2912	Transglutaminase-like superfamily
NA29_RS24225	COG0728	peptidoglycan biosynthetic process
NA29_RS24230	COG0268	Binds directly to 16S ribosomal RNA
NA29_RS24240	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NA29_RS24245	COG3123	guanosine phosphorylase activity
NA29_RS24255	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NA29_RS24265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NA29_RS24270	COG2197	response regulator
NA29_RS24295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NA29_RS24300	COG0318	PFAM AMP-dependent synthetase and ligase
NA29_RS24305	COG4974	Belongs to the 'phage' integrase family
NA29_RS24310	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NA29_RS24315	COG0802	atpase or kinase
NA29_RS24320	COG0860	N-Acetylmuramoyl-L-alanine amidase
NA29_RS24325	COG0586	Pfam SNARE associated Golgi protein
NA29_RS24330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NA29_RS24335	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NA29_RS24345	COG3842	ATPase activity
NA29_RS24355	COG1176	ABC-type spermidine putrescine transport system, permease component I
NA29_RS24360	COG0006	proline dipeptidase activity
NA29_RS24365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NA29_RS24380	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NA29_RS24390	COG0617	tRNA 3'-terminal CCA addition
NA29_RS24395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NA29_RS24400	COG1428	Deoxynucleoside kinase
NA29_RS24405	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NA29_RS24410	COG0642	Histidine kinase
NA29_RS24425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NA29_RS24440	COG0484	heat shock protein binding
NA29_RS24445	COG0443	Heat shock 70 kDa protein
NA29_RS24455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NA29_RS24470	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NA29_RS24490	COG0497	DNA recombination
NA29_RS24495	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NA29_RS24505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NA29_RS24510	COG0312	modulator of DNA gyrase
NA29_RS24515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NA29_RS24520	COG2096	Adenosyltransferase
NA29_RS24525	COG0277	FAD linked oxidase domain protein
NA29_RS24530	COG0277	FAD linked oxidase domain protein
NA29_RS24535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NA29_RS24540	COG0277	FAD linked oxidase domain protein
NA29_RS24545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NA29_RS24555	COG0386	Belongs to the glutathione peroxidase family
NA29_RS24570	COG3023	N-Acetylmuramoyl-L-alanine amidase
NA29_RS24575	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NA29_RS24585	COG0672	)-iron permease
NA29_RS24590	COG4633	Protein conserved in bacteria
NA29_RS24605	COG0765	amino acid transport
NA29_RS24610	COG0765	amino acid transport
NA29_RS24615	COG1126	abc transporter atp-binding protein
NA29_RS24635	COG0659	secondary active sulfate transmembrane transporter activity
NA29_RS24640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NA29_RS24655	COG1230	cation diffusion facilitator family transporter
NA29_RS24660	COG0583	DNA-binding transcription factor activity
NA29_RS24665	COG1028	Short-chain dehydrogenase reductase Sdr
NA29_RS24715	COG0583	DNA-binding transcription factor activity
NA29_RS24760	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NA29_RS24765	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
NA29_RS24790	COG2721	sulfolactate sulfo-lyase activity
NA29_RS24795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NA29_RS24810	COG1595	DNA-templated transcription, initiation
NA29_RS24820	COG0840	transmembrane signaling receptor activity
NA29_RS24835	COG3842	ATPase activity
NA29_RS24845	COG4948	Mandelate Racemase Muconate Lactonizing
NA29_RS24850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NA29_RS24855	COG2188	Transcriptional regulator
NA29_RS24865	COG2207	Transcriptional regulator
NA29_RS24890	COG1214	PFAM Peptidase M22, glycoprotease
NA29_RS24890	COG0456	acetyltransferase
NA29_RS24900	COG0583	DNA-binding transcription factor activity
NA29_RS24915	COG0625	glutathione transferase activity
NA29_RS24945	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NA29_RS24950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NA29_RS24955	COG0322	excinuclease ABC activity
NA29_RS24965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NA29_RS24975	COG0736	holo-[acyl-carrier-protein] synthase activity
NA29_RS24990	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NA29_RS24995	COG0571	ribonuclease III activity
NA29_RS25000	COG0681	Belongs to the peptidase S26 family
NA29_RS25015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NA29_RS25035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NA29_RS25040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NA29_RS25060	COG0416	fatty acid biosynthetic process
NA29_RS25065	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NA29_RS25070	COG1399	metal-binding, possibly nucleic acid-binding protein
NA29_RS25075	COG0424	maF-like protein
NA29_RS25080	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NA29_RS25085	COG0616	signal peptide processing
NA29_RS25085	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NA29_RS25095	COG0546	phosphoglycolate phosphatase activity
NA29_RS25100	COG0564	pseudouridine synthase activity
NA29_RS25105	COG1530	ribonuclease E activity
NA29_RS25110	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NA29_RS25125	COG0303	'Molybdopterin
NA29_RS25135	COG0456	acetyltransferase
NA29_RS25155	COG1556	Lactate utilization protein
NA29_RS25165	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NA29_RS25190	COG0277	FAD linked oxidase domain protein
NA29_RS25195	COG0277	FAD linked oxidase domain protein
NA29_RS25200	COG0247	lactate metabolic process
NA29_RS25210	COG3384	dioxygenase
NA29_RS25320	COG0741	lytic transglycosylase activity
NA29_RS25410	COG3250	beta-galactosidase activity
NA29_RS25425	COG0475	glutathione-regulated potassium exporter activity
NA29_RS25470	COG1846	Transcriptional regulator
NA29_RS25475	COG0582	viral genome integration into host DNA
NA29_RS25530	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NA29_RS25530	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NA29_RS25595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3