locus-tag	class	description
PATSB16_RS00030	COG1473	amidohydrolase
PATSB16_RS00035	COG0243	molybdopterin cofactor binding
PATSB16_RS00050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PATSB16_RS00055	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
PATSB16_RS00060	COG2001	Belongs to the MraZ family
PATSB16_RS00065	COG0275	rRNA processing
PATSB16_RS00070	COG3116	cell division
PATSB16_RS00080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PATSB16_RS00085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PATSB16_RS00115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PATSB16_RS00120	COG1181	Belongs to the D-alanine--D-alanine ligase family
PATSB16_RS00125	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PATSB16_RS00135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PATSB16_RS00150	COG0653	protein targeting
PATSB16_RS00165	COG0494	nUDIX hydrolase
PATSB16_RS00170	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PATSB16_RS00175	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
PATSB16_RS00200	COG4536	flavin adenine dinucleotide binding
PATSB16_RS00210	COG0142	geranyltranstransferase activity
PATSB16_RS00215	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PATSB16_RS00220	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PATSB16_RS00225	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PATSB16_RS00250	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PATSB16_RS00255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PATSB16_RS00260	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PATSB16_RS00275	COG3023	N-Acetylmuramoyl-L-alanine amidase
PATSB16_RS00310	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PATSB16_RS00325	COG0439	Biotin carboxylase
PATSB16_RS00330	COG0511	ligase activity, forming carbon-carbon bonds
PATSB16_RS00335	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PATSB16_RS00350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PATSB16_RS00355	COG3150	esterase
PATSB16_RS00370	COG0632	four-way junction helicase activity
PATSB16_RS00380	COG1981	membrane
PATSB16_RS00390	COG0800	Aldolase
PATSB16_RS00400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PATSB16_RS00425	COG0482	sulfurtransferase activity
PATSB16_RS00430	COG0069	glutamate synthase activity
PATSB16_RS00435	COG0625	glutathione transferase activity
PATSB16_RS00445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PATSB16_RS00450	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PATSB16_RS00455	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PATSB16_RS00460	COG1862	Preprotein translocase
PATSB16_RS00465	COG0343	queuine tRNA-ribosyltransferase activity
PATSB16_RS00470	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PATSB16_RS00475	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PATSB16_RS00485	COG0583	DNA-binding transcription factor activity
PATSB16_RS00490	COG0783	Belongs to the Dps family
PATSB16_RS00495	COG3344	reverse transcriptase
PATSB16_RS00515	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PATSB16_RS00535	COG0386	Belongs to the glutathione peroxidase family
PATSB16_RS00540	COG1346	cytolysis
PATSB16_RS00545	COG1380	Effector of murein hydrolase LrgA
PATSB16_RS00550	COG0247	lactate metabolic process
PATSB16_RS00555	COG0277	FAD linked oxidase domain protein
PATSB16_RS00560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PATSB16_RS00565	COG0277	FAD linked oxidase domain protein
PATSB16_RS00570	COG0277	FAD linked oxidase domain protein
PATSB16_RS00575	COG2096	Adenosyltransferase
PATSB16_RS00580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PATSB16_RS00585	COG0312	modulator of DNA gyrase
PATSB16_RS00590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PATSB16_RS00600	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PATSB16_RS00605	COG0497	DNA recombination
PATSB16_RS00615	COG1420	regulation of RNA biosynthetic process
PATSB16_RS00625	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PATSB16_RS00640	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PATSB16_RS00645	COG0443	Heat shock 70 kDa protein
PATSB16_RS00650	COG0484	heat shock protein binding
PATSB16_RS00655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PATSB16_RS00655	COG0512	Glutamine amidotransferase of anthranilate synthase
PATSB16_RS00660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PATSB16_RS00665	COG1428	Deoxynucleoside kinase
PATSB16_RS00670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PATSB16_RS00685	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PATSB16_RS00690	COG0628	permease
PATSB16_RS00705	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PATSB16_RS00710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PATSB16_RS00715	COG0586	Pfam SNARE associated Golgi protein
PATSB16_RS00720	COG0860	N-Acetylmuramoyl-L-alanine amidase
PATSB16_RS00725	COG0802	atpase or kinase
PATSB16_RS00730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PATSB16_RS00735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PATSB16_RS00740	COG4974	Belongs to the 'phage' integrase family
PATSB16_RS00745	COG0318	PFAM AMP-dependent synthetase and ligase
PATSB16_RS00755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PATSB16_RS00760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PATSB16_RS00775	COG3123	guanosine phosphorylase activity
PATSB16_RS00780	COG0137	argininosuccinate synthase activity
PATSB16_RS00785	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PATSB16_RS00795	COG0268	Binds directly to 16S ribosomal RNA
PATSB16_RS00800	COG0728	peptidoglycan biosynthetic process
PATSB16_RS00805	COG2912	Transglutaminase-like superfamily
PATSB16_RS00820	COG0563	adenylate kinase activity
PATSB16_RS00825	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PATSB16_RS00845	COG0811	peptide transport
PATSB16_RS00850	COG1570	exodeoxyribonuclease VII activity
PATSB16_RS00855	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PATSB16_RS00880	COG1278	Cold shock
PATSB16_RS00885	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PATSB16_RS00890	COG0542	response to heat
PATSB16_RS00895	COG0756	dUTP diphosphatase activity
PATSB16_RS00900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PATSB16_RS00905	COG2814	Major facilitator Superfamily
PATSB16_RS00915	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PATSB16_RS00920	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PATSB16_RS00925	COG0196	riboflavin kinase activity
PATSB16_RS00930	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PATSB16_RS00935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PATSB16_RS00935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PATSB16_RS00940	COG3264	Mechanosensitive ion channel
PATSB16_RS00940	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PATSB16_RS00950	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PATSB16_RS00960	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PATSB16_RS00970	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PATSB16_RS00975	COG2003	Belongs to the UPF0758 family
PATSB16_RS00980	COG1047	Peptidyl-prolyl cis-trans
PATSB16_RS00985	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PATSB16_RS01005	COG0411	ABC transporter
PATSB16_RS01020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PATSB16_RS01025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PATSB16_RS01025	COG0543	2 iron, 2 sulfur cluster binding
PATSB16_RS01070	COG3237	CsbD-like
PATSB16_RS01075	COG4585	Histidine kinase
PATSB16_RS01090	COG2197	response regulator
PATSB16_RS01095	COG2201	protein-glutamate methylesterase activity
PATSB16_RS01100	COG3300	MHYT domain
PATSB16_RS01100	COG5001	Diguanylate cyclase
PATSB16_RS01110	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PATSB16_RS01115	COG0741	lytic transglycosylase activity
PATSB16_RS01120	COG0436	Aminotransferase
PATSB16_RS01125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PATSB16_RS01130	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PATSB16_RS01140	COG4336	lyase activity
PATSB16_RS01145	COG0583	DNA-binding transcription factor activity
PATSB16_RS01155	COG0583	DNA-binding transcription factor activity
PATSB16_RS01195	COG0506	proline dehydrogenase activity
PATSB16_RS01205	COG1686	Belongs to the peptidase S11 family
PATSB16_RS01215	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PATSB16_RS01215	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PATSB16_RS01230	COG1704	LemA family
PATSB16_RS01235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PATSB16_RS01240	COG0671	phosphoesterase, PA-phosphatase related
PATSB16_RS01245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PATSB16_RS01255	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PATSB16_RS01265	COG0837	glucose binding
PATSB16_RS01265	COG1737	Transcriptional regulator
PATSB16_RS01270	COG3360	Dodecin
PATSB16_RS01275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PATSB16_RS01285	COG2181	nitrate reductase activity
PATSB16_RS01290	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PATSB16_RS01295	COG1140	nitrate reductase beta subunit
PATSB16_RS01300	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PATSB16_RS01310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PATSB16_RS01310	COG1017	nitric oxide dioxygenase activity
PATSB16_RS01335	COG1176	ABC-type spermidine putrescine transport system, permease component I
PATSB16_RS01340	COG1116	anion transmembrane transporter activity
PATSB16_RS01345	COG0640	Transcriptional regulator
PATSB16_RS01365	COG0477	Major facilitator Superfamily
PATSB16_RS01370	COG0477	Major facilitator Superfamily
PATSB16_RS01375	COG0531	amino acid
PATSB16_RS01385	COG0583	DNA-binding transcription factor activity
PATSB16_RS01400	COG4977	sequence-specific DNA binding
PATSB16_RS01405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PATSB16_RS01410	COG0765	amino acid transport
PATSB16_RS01415	COG1126	abc transporter atp-binding protein
PATSB16_RS01420	COG0252	asparaginase activity
PATSB16_RS01445	COG0457	Tetratricopeptide repeat
PATSB16_RS01455	COG1960	acyl-CoA dehydrogenase activity
PATSB16_RS01460	COG0318	PFAM AMP-dependent synthetase and ligase
PATSB16_RS01500	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PATSB16_RS01510	COG0315	cyclic pyranopterin monophosphate synthase activity
PATSB16_RS01520	COG0429	hydrolase of the alpha beta-hydrolase fold
PATSB16_RS01555	COG0126	phosphoglycerate kinase activity
PATSB16_RS01560	COG0469	pyruvate kinase activity
PATSB16_RS01570	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PATSB16_RS01575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PATSB16_RS01580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PATSB16_RS01585	COG0009	L-threonylcarbamoyladenylate synthase
PATSB16_RS01600	COG2027	D-alanyl-D-alanine carboxypeptidase
PATSB16_RS01610	COG0642	Histidine kinase
PATSB16_RS01615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PATSB16_RS01625	COG3608	succinylglutamate desuccinylase aspartoacylase
PATSB16_RS01625	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PATSB16_RS01665	COG1309	transcriptional regulator
PATSB16_RS01670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PATSB16_RS01675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PATSB16_RS01710	COG4970	Tfp pilus assembly protein FimT
PATSB16_RS01735	COG4575	ribosome binding
PATSB16_RS01740	COG0450	alkyl hydroperoxide reductase
PATSB16_RS01745	COG1960	acyl-CoA dehydrogenase activity
PATSB16_RS01755	COG3483	tryptophan 2,3-dioxygenase activity
PATSB16_RS01765	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PATSB16_RS01770	COG1522	sequence-specific DNA binding
PATSB16_RS01780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PATSB16_RS01785	COG2309	aminopeptidase activity
PATSB16_RS01790	COG0596	Alpha beta hydrolase
PATSB16_RS01805	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PATSB16_RS01815	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PATSB16_RS01820	COG0259	pyridoxamine-phosphate oxidase activity
PATSB16_RS01825	COG2982	Protein involved in outer membrane biogenesis
PATSB16_RS01830	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PATSB16_RS01835	COG0318	PFAM AMP-dependent synthetase and ligase
PATSB16_RS01855	COG0028	Belongs to the TPP enzyme family
PATSB16_RS01930	COG1012	belongs to the aldehyde dehydrogenase family
PATSB16_RS01940	COG0778	Nitroreductase
PATSB16_RS01955	COG2409	Drug exporters of the RND superfamily
PATSB16_RS01970	COG2207	Transcriptional regulator
PATSB16_RS01985	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PATSB16_RS01990	COG1845	cytochrome c oxidase, subunit III
PATSB16_RS01995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PATSB16_RS02000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PATSB16_RS02005	COG0477	Major facilitator Superfamily
PATSB16_RS02010	COG3002	Belongs to the UPF0753 family
PATSB16_RS02015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PATSB16_RS02020	COG0583	DNA-binding transcription factor activity
PATSB16_RS02035	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PATSB16_RS02045	COG0842	Transport permease protein
PATSB16_RS02050	COG0842	Transport permease protein
PATSB16_RS02050	COG1129	ABC transporter
PATSB16_RS02055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PATSB16_RS02070	COG1560	Kdo2-lipid A biosynthetic process
PATSB16_RS02105	COG4633	Protein conserved in bacteria
PATSB16_RS02160	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PATSB16_RS02175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PATSB16_RS02185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PATSB16_RS02310	COG4372	Transposase
PATSB16_RS02320	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PATSB16_RS02360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PATSB16_RS02375	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PATSB16_RS02390	COG0420	3'-5' exonuclease activity
PATSB16_RS02455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PATSB16_RS02475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PATSB16_RS02490	COG3328	transposase activity
PATSB16_RS02540	COG0583	DNA-binding transcription factor activity
PATSB16_RS02550	COG2159	amidohydrolase
PATSB16_RS02605	COG1139	Iron-sulfur cluster binding protein
PATSB16_RS02615	COG0247	lactate metabolic process
PATSB16_RS02620	COG2186	Transcriptional regulator
PATSB16_RS02625	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
PATSB16_RS02635	COG0302	gtp cyclohydrolase
PATSB16_RS02655	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
PATSB16_RS02660	COG5001	Diguanylate cyclase
PATSB16_RS02665	COG1024	Enoyl-CoA hydratase
PATSB16_RS02670	COG3300	MHYT domain
PATSB16_RS02670	COG5001	Diguanylate cyclase
PATSB16_RS02695	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PATSB16_RS02735	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PATSB16_RS02740	COG1802	Transcriptional regulator
PATSB16_RS02745	COG2814	Major facilitator Superfamily
PATSB16_RS02760	COG1113	amino acid transport
PATSB16_RS02770	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PATSB16_RS02775	COG0436	Aminotransferase
PATSB16_RS02805	COG2916	Histone family protein nucleoid-structuring protein H-NS
PATSB16_RS02820	COG2197	response regulator
PATSB16_RS02830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PATSB16_RS02835	COG1074	ATP-dependent DNA helicase activity
PATSB16_RS02840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PATSB16_RS02850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PATSB16_RS02855	COG1278	Cold shock
PATSB16_RS02865	COG1253	flavin adenine dinucleotide binding
PATSB16_RS02870	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PATSB16_RS02880	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PATSB16_RS02885	COG0840	transmembrane signaling receptor activity
PATSB16_RS02900	COG0513	Belongs to the DEAD box helicase family
PATSB16_RS02905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PATSB16_RS02910	COG1054	Belongs to the UPF0176 family
PATSB16_RS02925	COG1216	Glycosyl transferase, family 2
PATSB16_RS02925	COG0463	Glycosyl transferase, family 2
PATSB16_RS02950	COG1530	ribonuclease E activity
PATSB16_RS02955	COG0424	maF-like protein
PATSB16_RS02960	COG0584	glycerophosphoryl diester phosphodiesterase
PATSB16_RS02970	COG0395	ABC-type sugar transport system, permease component
PATSB16_RS02975	COG1175	transmembrane transport
PATSB16_RS02980	COG1653	transport
PATSB16_RS02985	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PATSB16_RS02990	COG0799	negative regulation of ribosome biogenesis
PATSB16_RS02995	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PATSB16_RS03000	COG0408	coproporphyrinogen oxidase activity
PATSB16_RS03020	COG0151	Belongs to the GarS family
PATSB16_RS03025	COG0217	transcriptional regulatory protein
PATSB16_RS03030	COG1620	l-lactate permease
PATSB16_RS03035	COG0697	spore germination
PATSB16_RS03060	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PATSB16_RS03065	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PATSB16_RS03075	COG0583	DNA-binding transcription factor activity
PATSB16_RS03080	COG3284	Transcriptional regulator
PATSB16_RS03085	COG0583	DNA-binding transcription factor activity
PATSB16_RS03090	COG3328	transposase activity
PATSB16_RS03095	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS03105	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PATSB16_RS03110	COG0183	Belongs to the thiolase family
PATSB16_RS03115	COG0318	PFAM AMP-dependent synthetase and ligase
PATSB16_RS03130	COG0436	Aminotransferase
PATSB16_RS03155	COG2721	sulfolactate sulfo-lyase activity
PATSB16_RS03165	COG0667	Aldo Keto reductase
PATSB16_RS03180	COG4608	Belongs to the ABC transporter superfamily
PATSB16_RS03185	COG0444	Belongs to the ABC transporter superfamily
PATSB16_RS03190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PATSB16_RS03195	COG0747	negative chemotaxis
PATSB16_RS03200	COG1473	amidohydrolase
PATSB16_RS03205	COG0601	transmembrane transport
PATSB16_RS03255	COG2169	Transcriptional regulator
PATSB16_RS03255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PATSB16_RS03270	COG2814	Major facilitator Superfamily
PATSB16_RS03275	COG2860	membrane
PATSB16_RS03295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PATSB16_RS03300	COG0456	acetyltransferase
PATSB16_RS03305	COG0456	acetyltransferase
PATSB16_RS03305	COG1846	Transcriptional regulator
PATSB16_RS03325	COG0667	Aldo Keto reductase
PATSB16_RS03340	COG1752	Esterase of the alpha-beta hydrolase superfamily
PATSB16_RS03345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PATSB16_RS03350	COG1280	lysine exporter protein (LysE YggA)
PATSB16_RS03355	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS03355	COG0604	alcohol dehydrogenase
PATSB16_RS03355	COG3321	synthase
PATSB16_RS03360	COG0583	DNA-binding transcription factor activity
PATSB16_RS03395	COG0789	Transcriptional regulator
PATSB16_RS03420	COG0477	Major facilitator Superfamily
PATSB16_RS03420	COG2814	Major facilitator Superfamily
PATSB16_RS03425	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PATSB16_RS03445	COG0583	DNA-binding transcription factor activity
PATSB16_RS03450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PATSB16_RS03475	COG0640	Transcriptional regulator
PATSB16_RS03490	COG1959	2 iron, 2 sulfur cluster binding
PATSB16_RS03500	COG2151	metal-sulfur cluster biosynthetic enzyme
PATSB16_RS03520	COG1686	Belongs to the peptidase S11 family
PATSB16_RS03530	COG2084	Dehydrogenase
PATSB16_RS03550	COG0583	DNA-binding transcription factor activity
PATSB16_RS03555	COG0730	response to heat
PATSB16_RS03560	COG0175	sulfate reduction
PATSB16_RS03570	COG2895	sulfate adenylyltransferase (ATP) activity
PATSB16_RS03575	COG1648	precorrin-2 dehydrogenase activity
PATSB16_RS03575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PATSB16_RS03590	COG0795	lipopolysaccharide-transporting ATPase activity
PATSB16_RS03595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PATSB16_RS03615	COG0583	DNA-binding transcription factor activity
PATSB16_RS03620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PATSB16_RS03625	COG1802	Transcriptional regulator
PATSB16_RS03650	COG0410	ABC transporter
PATSB16_RS03665	COG1228	amidohydrolase
PATSB16_RS03670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PATSB16_RS03685	COG1024	Enoyl-CoA hydratase
PATSB16_RS03690	COG0318	PFAM AMP-dependent synthetase and ligase
PATSB16_RS03725	COG4206	TonB-dependent receptor
PATSB16_RS03730	COG4139	cobalamin transport
PATSB16_RS03735	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PATSB16_RS03740	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PATSB16_RS03745	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PATSB16_RS03755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PATSB16_RS03770	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PATSB16_RS03775	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PATSB16_RS03780	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PATSB16_RS03790	COG0729	surface antigen
PATSB16_RS03805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PATSB16_RS03805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PATSB16_RS03810	COG3047	cAMP biosynthetic process
PATSB16_RS03810	COG2885	chlorophyll binding
PATSB16_RS03815	COG0489	protein tyrosine kinase activity
PATSB16_RS03820	COG0717	Belongs to the dCTP deaminase family
PATSB16_RS03850	COG1595	DNA-templated transcription, initiation
PATSB16_RS03860	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PATSB16_RS03865	COG0181	hydroxymethylbilane synthase activity
PATSB16_RS03885	COG2271	Major facilitator Superfamily
PATSB16_RS03900	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PATSB16_RS03905	COG0247	lactate metabolic process
PATSB16_RS03910	COG0277	FAD linked oxidase domain protein
PATSB16_RS03915	COG0277	FAD linked oxidase domain protein
PATSB16_RS03935	COG0347	Belongs to the P(II) protein family
PATSB16_RS03940	COG2840	Smr protein MutS2
PATSB16_RS03945	COG0492	ferredoxin-NADP+ reductase activity
PATSB16_RS03950	COG1674	ftsk spoiiie
PATSB16_RS03955	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PATSB16_RS03960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PATSB16_RS03965	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PATSB16_RS03975	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PATSB16_RS03990	COG0642	Histidine kinase
PATSB16_RS04025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PATSB16_RS04045	COG1850	ribulose-bisphosphate carboxylase activity
PATSB16_RS04055	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PATSB16_RS04065	COG1609	Transcriptional regulator
PATSB16_RS04075	COG3842	ATPase activity
PATSB16_RS04095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PATSB16_RS04100	COG0583	DNA-binding transcription factor activity
PATSB16_RS04105	COG1929	Belongs to the glycerate kinase type-1 family
PATSB16_RS04115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PATSB16_RS04125	COG1012	belongs to the aldehyde dehydrogenase family
PATSB16_RS04140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PATSB16_RS04145	COG3938	Belongs to the proline racemase family
PATSB16_RS04150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PATSB16_RS04165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PATSB16_RS04170	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PATSB16_RS04180	COG1561	YicC-like family, N-terminal region
PATSB16_RS04195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PATSB16_RS04205	COG1741	Belongs to the pirin family
PATSB16_RS04225	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PATSB16_RS04230	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PATSB16_RS04235	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PATSB16_RS04240	COG2205	protein histidine kinase activity
PATSB16_RS04245	COG0745	RESPONSE REGULATOR receiver
PATSB16_RS04260	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PATSB16_RS04270	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PATSB16_RS04290	COG0438	transferase activity, transferring glycosyl groups
PATSB16_RS04320	COG0028	Belongs to the TPP enzyme family
PATSB16_RS04325	COG0440	acetolactate synthase activity
PATSB16_RS04335	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PATSB16_RS04340	COG0688	phosphatidylethanolamine metabolic process
PATSB16_RS04345	COG1183	phosphatidylcholine synthase activity
PATSB16_RS04350	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PATSB16_RS04395	COG0589	response to stress
PATSB16_RS04415	COG0415	Belongs to the DNA photolyase family
PATSB16_RS04420	COG0300	oxidoreductase activity
PATSB16_RS04440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PATSB16_RS04450	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
PATSB16_RS04455	COG1309	transcriptional regulator
PATSB16_RS04475	COG1846	Transcriptional regulator
PATSB16_RS04480	COG1764	response to oxidative stress
PATSB16_RS04505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PATSB16_RS04515	COG1595	DNA-templated transcription, initiation
PATSB16_RS04520	COG0006	proline dipeptidase activity
PATSB16_RS04525	COG0308	aminopeptidase N
PATSB16_RS04535	COG1522	sequence-specific DNA binding
PATSB16_RS04560	COG4178	(ABC) transporter
PATSB16_RS04565	COG0312	modulator of DNA gyrase
PATSB16_RS04570	COG0312	modulator of DNA gyrase
PATSB16_RS04585	COG0492	ferredoxin-NADP+ reductase activity
PATSB16_RS04610	COG0667	Aldo Keto reductase
PATSB16_RS04615	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS04655	COG1024	Enoyl-CoA hydratase
PATSB16_RS04665	COG1960	acyl-CoA dehydrogenase activity
PATSB16_RS04670	COG1562	ergosterol biosynthetic process
PATSB16_RS04675	COG1657	PFAM Prenyltransferase squalene oxidase
PATSB16_RS04690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PATSB16_RS04695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PATSB16_RS04725	COG2153	protein acetylation
PATSB16_RS04730	COG0488	(ABC) transporter
PATSB16_RS04755	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PATSB16_RS04765	COG0583	DNA-binding transcription factor activity
PATSB16_RS04770	COG2814	Major facilitator Superfamily
PATSB16_RS04790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PATSB16_RS04795	COG0697	spore germination
PATSB16_RS04810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PATSB16_RS04820	COG3161	chorismate lyase activity
PATSB16_RS04850	COG3135	benzoate transporter
PATSB16_RS04885	COG0778	Nitroreductase
PATSB16_RS04890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PATSB16_RS04895	COG2878	Part of a membrane complex involved in electron transport
PATSB16_RS04900	COG1309	transcriptional regulator
PATSB16_RS04915	COG0556	nucleotide-excision repair
PATSB16_RS04925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PATSB16_RS04940	COG1104	cysteine desulfurase activity
PATSB16_RS04945	COG0822	iron-sulfur transferase activity
PATSB16_RS04950	COG0316	Belongs to the HesB IscA family
PATSB16_RS04960	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PATSB16_RS04975	COG2975	iron-sulfur cluster assembly
PATSB16_RS05000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PATSB16_RS05020	COG0084	hydrolase, TatD family'
PATSB16_RS05025	COG2333	competence protein COMEC
PATSB16_RS05025	COG0658	competence protein
PATSB16_RS05030	COG2267	carboxylic ester hydrolase activity
PATSB16_RS05035	COG0504	CTP synthase activity
PATSB16_RS05040	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PATSB16_RS05045	COG0148	phosphopyruvate hydratase activity
PATSB16_RS05050	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PATSB16_RS05060	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PATSB16_RS05070	COG2833	Protein of unknown function (DUF455)
PATSB16_RS05080	COG0613	PHP domain protein
PATSB16_RS05085	COG0009	L-threonylcarbamoyladenylate synthase
PATSB16_RS05090	COG1994	Peptidase M50
PATSB16_RS05095	COG0180	Tryptophanyl-tRNA synthetase
PATSB16_RS05105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PATSB16_RS05110	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PATSB16_RS05115	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PATSB16_RS05115	COG0321	lipoyl(octanoyl) transferase activity
PATSB16_RS05130	COG2850	peptidyl-arginine hydroxylation
PATSB16_RS05140	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PATSB16_RS05150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PATSB16_RS05155	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PATSB16_RS05160	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PATSB16_RS05180	COG0776	regulation of translation
PATSB16_RS05195	COG0105	UTP biosynthetic process
PATSB16_RS05215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PATSB16_RS05220	COG0124	histidyl-tRNA synthetase
PATSB16_RS05225	COG2976	Protein conserved in bacteria
PATSB16_RS05230	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PATSB16_RS05240	COG1923	regulation of RNA biosynthetic process
PATSB16_RS05245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PATSB16_RS05250	COG0330	HflC and HflK could
PATSB16_RS05255	COG0330	HflC and HflK could
PATSB16_RS05265	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PATSB16_RS05275	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
PATSB16_RS05285	COG1959	2 iron, 2 sulfur cluster binding
PATSB16_RS05295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PATSB16_RS05300	COG4566	intracellular signal transduction
PATSB16_RS05310	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PATSB16_RS05315	COG0508	dehydrogenase complex catalyzes the overall conversion of
PATSB16_RS05325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PATSB16_RS05340	COG1686	Belongs to the peptidase S11 family
PATSB16_RS05345	COG1414	Transcriptional regulator
PATSB16_RS05360	COG0765	amino acid transport
PATSB16_RS05365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PATSB16_RS05370	COG0167	dihydroorotate dehydrogenase activity
PATSB16_RS05375	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PATSB16_RS05395	COG0583	DNA-binding transcription factor activity
PATSB16_RS05420	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PATSB16_RS05440	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PATSB16_RS05445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PATSB16_RS05450	COG0567	Dehydrogenase, E1 component
PATSB16_RS05455	COG0508	dehydrogenase complex catalyzes the overall conversion of
PATSB16_RS05460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PATSB16_RS05465	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PATSB16_RS05480	COG5642	Protein of unknown function (DUF2384)
PATSB16_RS05485	COG5654	RES domain protein
PATSB16_RS05505	COG1846	Transcriptional regulator
PATSB16_RS05525	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PATSB16_RS05540	COG4964	Belongs to the GSP D family
PATSB16_RS05590	COG3158	transport of potassium into the cell
PATSB16_RS05595	COG1297	OPT oligopeptide transporter protein
PATSB16_RS05600	COG0477	Major facilitator Superfamily
PATSB16_RS05610	COG2183	response to ionizing radiation
PATSB16_RS05625	COG1199	ATP-dependent helicase activity
PATSB16_RS05635	COG0564	pseudouridine synthase activity
PATSB16_RS05645	COG3243	poly(R)-hydroxyalkanoic acid synthase
PATSB16_RS05650	COG0183	Belongs to the thiolase family
PATSB16_RS05655	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS05665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PATSB16_RS05675	COG0183	Belongs to the thiolase family
PATSB16_RS05705	COG0288	reversible hydration of carbon dioxide
PATSB16_RS05710	COG0626	cystathionine gamma-synthase activity
PATSB16_RS05715	COG0560	Phosphoserine phosphatase
PATSB16_RS05750	COG0725	ABC transporter, periplasmic molybdate-binding protein
PATSB16_RS05760	COG3842	ATPase activity
PATSB16_RS05770	COG0625	glutathione transferase activity
PATSB16_RS05785	COG3038	cytochrome b561
PATSB16_RS05805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PATSB16_RS05835	COG1686	Belongs to the peptidase S11 family
PATSB16_RS05855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PATSB16_RS05890	COG3038	cytochrome b561
PATSB16_RS05905	COG3384	dioxygenase
PATSB16_RS05915	COG1960	acyl-CoA dehydrogenase activity
PATSB16_RS05920	COG1902	pentaerythritol trinitrate reductase activity
PATSB16_RS05925	COG0183	Belongs to the thiolase family
PATSB16_RS05955	COG0840	transmembrane signaling receptor activity
PATSB16_RS05960	COG5001	Diguanylate cyclase
PATSB16_RS05965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PATSB16_RS05970	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PATSB16_RS05985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PATSB16_RS06005	COG1522	sequence-specific DNA binding
PATSB16_RS06020	COG2235	arginine
PATSB16_RS06025	COG1982	Orn Lys Arg decarboxylase major
PATSB16_RS06030	COG0531	amino acid
PATSB16_RS06035	COG0477	Major facilitator Superfamily
PATSB16_RS06040	COG2814	Major facilitator Superfamily
PATSB16_RS06045	COG1902	pentaerythritol trinitrate reductase activity
PATSB16_RS06080	COG2375	cellular response to nickel ion
PATSB16_RS06095	COG1802	Transcriptional regulator
PATSB16_RS06100	COG2271	Major facilitator Superfamily
PATSB16_RS06110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PATSB16_RS06135	COG2207	Transcriptional regulator
PATSB16_RS06140	COG0583	DNA-binding transcription factor activity
PATSB16_RS06145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PATSB16_RS06150	COG1024	Enoyl-CoA hydratase
PATSB16_RS06160	COG0477	Major facilitator Superfamily
PATSB16_RS06165	COG0583	DNA-binding transcription factor activity
PATSB16_RS06185	COG0583	DNA-binding transcription factor activity
PATSB16_RS06200	COG2814	Major facilitator Superfamily
PATSB16_RS06225	COG0583	DNA-binding transcription factor activity
PATSB16_RS06235	COG0697	spore germination
PATSB16_RS06240	COG0778	Nitroreductase
PATSB16_RS06245	COG0583	DNA-binding transcription factor activity
PATSB16_RS06250	COG1819	glycosyl
PATSB16_RS06265	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PATSB16_RS06270	COG2188	Transcriptional regulator
PATSB16_RS06275	COG2814	Major facilitator Superfamily
PATSB16_RS06295	COG0583	DNA-binding transcription factor activity
PATSB16_RS06335	COG0346	lactoylglutathione lyase activity
PATSB16_RS06340	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PATSB16_RS06345	COG3261	NADH dehydrogenase
PATSB16_RS06345	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
PATSB16_RS06350	COG0651	ATP synthesis coupled electron transport
PATSB16_RS06360	COG0650	Formate hydrogenlyase subunit 4
PATSB16_RS06365	COG0651	ATP synthesis coupled electron transport
PATSB16_RS06380	COG0129	dihydroxy-acid dehydratase activity
PATSB16_RS06390	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
PATSB16_RS06410	COG0523	cobalamin synthesis protein
PATSB16_RS06450	COG0179	Fumarylacetoacetate (FAA) hydrolase
PATSB16_RS06455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PATSB16_RS06480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PATSB16_RS06510	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PATSB16_RS06530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PATSB16_RS06535	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PATSB16_RS06545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PATSB16_RS06555	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PATSB16_RS06565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PATSB16_RS06570	COG4988	ABC transporter
PATSB16_RS06580	COG1294	oxidase, subunit
PATSB16_RS06585	COG1271	oxidase subunit
PATSB16_RS06600	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS06610	COG0667	Aldo Keto reductase
PATSB16_RS06620	COG0456	acetyltransferase
PATSB16_RS06650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PATSB16_RS06655	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PATSB16_RS06685	COG3344	reverse transcriptase
PATSB16_RS06695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PATSB16_RS06700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PATSB16_RS06730	COG5001	Diguanylate cyclase
PATSB16_RS06730	COG3300	MHYT domain
PATSB16_RS06745	COG1522	sequence-specific DNA binding
PATSB16_RS06755	COG0596	Alpha beta hydrolase
PATSB16_RS06765	COG0583	DNA-binding transcription factor activity
PATSB16_RS06770	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PATSB16_RS06790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PATSB16_RS06805	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PATSB16_RS06810	COG0477	Major facilitator Superfamily
PATSB16_RS06820	COG1595	DNA-templated transcription, initiation
PATSB16_RS06835	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PATSB16_RS06845	COG4221	oxidoreductase activity
PATSB16_RS06855	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PATSB16_RS06860	COG4941	Belongs to the sigma-70 factor family
PATSB16_RS06865	COG2764	glyoxalase bleomycin resistance protein dioxygenase
PATSB16_RS06870	COG3795	YCII-related domain
PATSB16_RS06880	COG0640	Transcriptional regulator
PATSB16_RS06935	COG1802	Transcriptional regulator
PATSB16_RS06955	COG4572	Cation transport regulator
PATSB16_RS06965	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PATSB16_RS06970	COG3842	ATPase activity
PATSB16_RS06975	COG1176	ABC-type spermidine putrescine transport system, permease component I
PATSB16_RS06980	COG1177	transmembrane transport
PATSB16_RS06990	COG0456	acetyltransferase
PATSB16_RS06990	COG1214	PFAM Peptidase M22, glycoprotease
PATSB16_RS07000	COG0765	amino acid transport
PATSB16_RS07005	COG1126	abc transporter atp-binding protein
PATSB16_RS07015	COG0477	Major facilitator Superfamily
PATSB16_RS07020	COG0154	amidase activity
PATSB16_RS07035	COG1914	H( )-stimulated, divalent metal cation uptake system
PATSB16_RS07080	COG0583	DNA-binding transcription factor activity
PATSB16_RS07105	COG0589	response to stress
PATSB16_RS07110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PATSB16_RS07145	COG2301	Belongs to the HpcH HpaI aldolase family
PATSB16_RS07155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PATSB16_RS07160	COG1960	acyl-CoA dehydrogenase activity
PATSB16_RS07170	COG2271	Major facilitator Superfamily
PATSB16_RS07185	COG0671	phosphoesterase, PA-phosphatase related
PATSB16_RS07190	COG0642	Histidine kinase
PATSB16_RS07200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PATSB16_RS07235	COG2031	fatty acid transporter
PATSB16_RS07250	COG0625	glutathione transferase activity
PATSB16_RS07255	COG0024	Methionine aminopeptidase
PATSB16_RS07270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PATSB16_RS07290	COG0667	Aldo Keto reductase
PATSB16_RS07310	COG1309	transcriptional regulator
PATSB16_RS07320	COG1294	oxidase, subunit
PATSB16_RS07325	COG1271	oxidase subunit
PATSB16_RS07335	COG3550	peptidyl-serine autophosphorylation
PATSB16_RS07345	COG5002	protein histidine kinase activity
PATSB16_RS07345	COG5001	Diguanylate cyclase
PATSB16_RS07345	COG3447	MASE1 domain protein
PATSB16_RS07380	COG0840	transmembrane signaling receptor activity
PATSB16_RS07420	COG1309	transcriptional regulator
PATSB16_RS07425	COG1979	alcohol dehydrogenase
PATSB16_RS07450	COG0583	DNA-binding transcription factor activity
PATSB16_RS07460	COG3795	YCII-related domain
PATSB16_RS07490	COG3344	reverse transcriptase
PATSB16_RS07495	COG0583	DNA-binding transcription factor activity
PATSB16_RS07505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PATSB16_RS07525	COG0477	Major facilitator Superfamily
PATSB16_RS07535	COG0583	DNA-binding transcription factor activity
PATSB16_RS07550	COG0567	Dehydrogenase, E1 component
PATSB16_RS07575	COG0123	including yeast histone deacetylase and acetoin utilization protein
PATSB16_RS07600	COG1126	abc transporter atp-binding protein
PATSB16_RS07605	COG0765	amino acid transport
PATSB16_RS07615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PATSB16_RS07640	COG2855	membrane
PATSB16_RS07680	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PATSB16_RS07690	COG0655	NAD(P)H dehydrogenase (quinone) activity
PATSB16_RS07745	COG4964	Belongs to the GSP D family
PATSB16_RS07770	COG1414	Transcriptional regulator
PATSB16_RS07780	COG2161	toxin-antitoxin pair type II binding
PATSB16_RS07795	COG1024	Enoyl-CoA hydratase
PATSB16_RS07805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PATSB16_RS07810	COG0318	PFAM AMP-dependent synthetase and ligase
PATSB16_RS07835	COG2885	chlorophyll binding
PATSB16_RS07845	COG0477	Major facilitator Superfamily
PATSB16_RS07850	COG1414	Transcriptional regulator
PATSB16_RS07855	COG3246	L-lysine catabolic process to acetate
PATSB16_RS07860	COG0511	ligase activity, forming carbon-carbon bonds
PATSB16_RS07865	COG0439	Biotin carboxylase
PATSB16_RS07880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PATSB16_RS07885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PATSB16_RS07885	COG1116	anion transmembrane transporter activity
PATSB16_RS07890	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS07910	COG5001	Diguanylate cyclase
PATSB16_RS07910	COG5002	protein histidine kinase activity
PATSB16_RS07910	COG3447	MASE1 domain protein
PATSB16_RS07915	COG1024	Enoyl-CoA hydratase
PATSB16_RS07925	COG3842	ATPase activity
PATSB16_RS07930	COG1176	ABC-type spermidine putrescine transport system, permease component I
PATSB16_RS07935	COG0318	PFAM AMP-dependent synthetase and ligase
PATSB16_RS07945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PATSB16_RS07955	COG1802	Transcriptional regulator
PATSB16_RS07965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PATSB16_RS07975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PATSB16_RS07980	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PATSB16_RS08000	COG0583	DNA-binding transcription factor activity
PATSB16_RS08015	COG0583	DNA-binding transcription factor activity
PATSB16_RS08025	COG0469	pyruvate kinase activity
PATSB16_RS08035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PATSB16_RS08040	COG0450	alkyl hydroperoxide reductase
PATSB16_RS08060	COG1562	ergosterol biosynthetic process
PATSB16_RS08075	COG0850	regulation of cytokinetic process
PATSB16_RS08080	COG2894	cell division
PATSB16_RS08085	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PATSB16_RS08105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PATSB16_RS08110	COG0544	peptidyl-prolyl cis-trans isomerase activity
PATSB16_RS08115	COG0740	serine-type endopeptidase activity
PATSB16_RS08125	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PATSB16_RS08130	COG0776	regulation of translation
PATSB16_RS08145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PATSB16_RS08155	COG4181	ATPase activity
PATSB16_RS08160	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PATSB16_RS08160	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PATSB16_RS08165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PATSB16_RS08170	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PATSB16_RS08170	COG0047	phosphoribosylformylglycinamidine synthase activity
PATSB16_RS08175	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PATSB16_RS08180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PATSB16_RS08190	COG2917	probably involved in intracellular septation
PATSB16_RS08195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PATSB16_RS08200	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PATSB16_RS08205	COG0318	PFAM AMP-dependent synthetase and ligase
PATSB16_RS08220	COG1335	isochorismatase
PATSB16_RS08225	COG0183	Belongs to the thiolase family
PATSB16_RS08240	COG2130	NADP-dependent
PATSB16_RS08245	COG1454	alcohol dehydrogenase
PATSB16_RS08250	COG0657	acetylesterase activity
PATSB16_RS08255	COG1592	Rubrerythrin
PATSB16_RS08260	COG0247	lactate metabolic process
PATSB16_RS08280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PATSB16_RS08285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PATSB16_RS08345	COG0354	folic acid binding
PATSB16_RS08350	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PATSB16_RS08355	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PATSB16_RS08365	COG1247	-acetyltransferase
PATSB16_RS08370	COG0084	hydrolase, TatD family'
PATSB16_RS08380	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
PATSB16_RS08395	COG1254	Belongs to the acylphosphatase family
PATSB16_RS08415	COG1522	sequence-specific DNA binding
PATSB16_RS08440	COG4638	Rieske (2fe-2S)
PATSB16_RS08470	COG0783	Belongs to the Dps family
PATSB16_RS08475	COG0045	succinate-CoA ligase (ADP-forming) activity
PATSB16_RS08475	COG1042	CoA-binding domain protein
PATSB16_RS08475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PATSB16_RS08480	COG0598	Magnesium transport protein CorA
PATSB16_RS08485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PATSB16_RS08500	COG0735	belongs to the Fur family
PATSB16_RS08505	COG3023	N-Acetylmuramoyl-L-alanine amidase
PATSB16_RS08525	COG0583	DNA-binding transcription factor activity
PATSB16_RS08530	COG0596	Alpha beta hydrolase
PATSB16_RS08535	COG0038	chloride channel
PATSB16_RS08540	COG3302	dmso reductase anchor subunit
PATSB16_RS08545	COG0437	4 iron, 4 sulfur cluster binding
PATSB16_RS08550	COG0243	molybdopterin cofactor binding
PATSB16_RS08560	COG0277	FAD linked oxidase domain protein
PATSB16_RS08570	COG0583	DNA-binding transcription factor activity
PATSB16_RS08585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PATSB16_RS08590	COG0765	amino acid transport
PATSB16_RS08595	COG0765	amino acid transport
PATSB16_RS08610	COG2188	Transcriptional regulator
PATSB16_RS08615	COG2986	histidine ammonia-lyase
PATSB16_RS08620	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PATSB16_RS08630	COG1228	amidohydrolase
PATSB16_RS08665	COG0179	Fumarylacetoacetate (FAA) hydrolase
PATSB16_RS08675	COG1012	belongs to the aldehyde dehydrogenase family
PATSB16_RS08680	COG3384	dioxygenase
PATSB16_RS08690	COG3971	2-oxopent-4-enoate hydratase activity
PATSB16_RS08700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PATSB16_RS08705	COG0730	response to heat
PATSB16_RS08710	COG3258	Cytochrome c
PATSB16_RS08715	COG2863	cytochrome
PATSB16_RS08725	COG3453	Protein conserved in bacteria
PATSB16_RS08725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PATSB16_RS08730	COG3459	Glycosyltransferase 36 associated
PATSB16_RS08760	COG1215	transferase activity, transferring glycosyl groups
PATSB16_RS08775	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PATSB16_RS08845	COG5487	UPF0391 membrane protein
PATSB16_RS08875	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PATSB16_RS08905	COG0166	Belongs to the GPI family
PATSB16_RS08910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PATSB16_RS08925	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PATSB16_RS08965	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PATSB16_RS08970	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PATSB16_RS08975	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PATSB16_RS08975	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PATSB16_RS08985	COG0356	it plays a direct role in the translocation of protons across the membrane
PATSB16_RS09000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PATSB16_RS09005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PATSB16_RS09010	COG3243	poly(R)-hydroxyalkanoic acid synthase
PATSB16_RS09020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PATSB16_RS09045	COG0589	response to stress
PATSB16_RS09055	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PATSB16_RS09060	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS09115	COG0640	Transcriptional regulator
PATSB16_RS09135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PATSB16_RS09145	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PATSB16_RS09150	COG2326	polyphosphate kinase activity
PATSB16_RS09160	COG1584	GPR1 FUN34 yaaH family protein
PATSB16_RS09165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PATSB16_RS09170	COG2132	Multicopper oxidase
PATSB16_RS09180	COG0463	Glycosyl transferase, family 2
PATSB16_RS09200	COG1215	transferase activity, transferring glycosyl groups
PATSB16_RS09205	COG1984	allophanate hydrolase subunit 2
PATSB16_RS09210	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PATSB16_RS09225	COG0583	DNA-binding transcription factor activity
PATSB16_RS09235	COG3842	ATPase activity
PATSB16_RS09240	COG1176	ABC-type spermidine putrescine transport system, permease component I
PATSB16_RS09245	COG1177	transmembrane transport
PATSB16_RS09275	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PATSB16_RS09300	COG1566	PFAM secretion protein HlyD family protein
PATSB16_RS09315	COG0811	peptide transport
PATSB16_RS09320	COG0848	biopolymer transport protein
PATSB16_RS09350	COG1538	Outer membrane efflux protein
PATSB16_RS09355	COG0446	pyridine nucleotide-disulphide oxidoreductase
PATSB16_RS09400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PATSB16_RS09405	COG0477	Major facilitator Superfamily
PATSB16_RS09410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PATSB16_RS09425	COG0438	transferase activity, transferring glycosyl groups
PATSB16_RS09455	COG0739	heme binding
PATSB16_RS09465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PATSB16_RS09470	COG1228	amidohydrolase
PATSB16_RS09475	COG0523	cobalamin synthesis protein
PATSB16_RS09480	COG3193	protein, possibly involved in utilization of glycolate and propanediol
PATSB16_RS09520	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PATSB16_RS09545	COG0583	DNA-binding transcription factor activity
PATSB16_RS09550	COG3618	amidohydrolase
PATSB16_RS09560	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PATSB16_RS09570	COG0523	cobalamin synthesis protein
PATSB16_RS09575	COG2233	PERMEase
PATSB16_RS09585	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS09610	COG0559	Belongs to the binding-protein-dependent transport system permease family
PATSB16_RS09615	COG1172	Belongs to the binding-protein-dependent transport system permease family
PATSB16_RS09620	COG4191	Histidine kinase
PATSB16_RS09635	COG1802	Transcriptional regulator
PATSB16_RS09645	COG2020	methyltransferase activity
PATSB16_RS09650	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PATSB16_RS09680	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PATSB16_RS09690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PATSB16_RS09695	COG3394	polysaccharide catabolic process
PATSB16_RS09710	COG2223	nitrite transmembrane transporter activity
PATSB16_RS09720	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PATSB16_RS09725	COG3383	formate dehydrogenase (NAD+) activity
PATSB16_RS09800	COG3842	ATPase activity
PATSB16_RS09810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PATSB16_RS09830	COG2010	Cytochrome c
PATSB16_RS09830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PATSB16_RS09840	COG0583	DNA-binding transcription factor activity
PATSB16_RS09850	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PATSB16_RS09855	COG3842	ATPase activity
PATSB16_RS09860	COG1177	transmembrane transport
PATSB16_RS09865	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PATSB16_RS09875	COG1609	Transcriptional regulator
PATSB16_RS09895	COG3706	GGDEF domain
PATSB16_RS09915	COG0488	(ABC) transporter
PATSB16_RS09930	COG0583	DNA-binding transcription factor activity
PATSB16_RS09940	COG2233	PERMEase
PATSB16_RS09985	COG1113	amino acid transport
PATSB16_RS09995	COG4266	Belongs to the allantoicase family
PATSB16_RS10010	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PATSB16_RS10020	COG1953	Uracil, thiamine, allantoin
PATSB16_RS10025	COG2186	Transcriptional regulator
PATSB16_RS10030	COG0840	transmembrane signaling receptor activity
PATSB16_RS10035	COG1619	proteins homologs of microcin C7 resistance protein MccF
PATSB16_RS10055	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS10060	COG0798	PFAM Bile acid sodium symporter
PATSB16_RS10065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PATSB16_RS10090	COG0318	PFAM AMP-dependent synthetase and ligase
PATSB16_RS10120	COG0519	Catalyzes the synthesis of GMP from XMP
PATSB16_RS10120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PATSB16_RS10140	COG2914	Belongs to the UPF0125 (RnfH) family
PATSB16_RS10145	COG2867	negative regulation of translational initiation
PATSB16_RS10150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PATSB16_RS10155	COG0330	HflC and HflK could
PATSB16_RS10170	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PATSB16_RS10175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PATSB16_RS10185	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PATSB16_RS10190	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PATSB16_RS10200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PATSB16_RS10205	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
PATSB16_RS10215	COG0750	zinc metalloprotease
PATSB16_RS10230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PATSB16_RS10240	COG0528	UMP kinase activity
PATSB16_RS10245	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PATSB16_RS10250	COG0052	Belongs to the universal ribosomal protein uS2 family
PATSB16_RS10255	COG0024	Methionine aminopeptidase
PATSB16_RS10265	COG1187	pseudouridine synthase activity
PATSB16_RS10270	COG0242	peptide deformylase activity
PATSB16_RS10275	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PATSB16_RS10300	COG2171	N-acyltransferase activity
PATSB16_RS10305	COG1393	Belongs to the ArsC family
PATSB16_RS10315	COG2890	protein-(glutamine-N5) methyltransferase activity
PATSB16_RS10320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PATSB16_RS10325	COG0488	(ABC) transporter
PATSB16_RS10335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PATSB16_RS10340	COG0477	Major facilitator Superfamily
PATSB16_RS10345	COG0351	phosphomethylpyrimidine kinase
PATSB16_RS10355	COG1573	uracil-dna glycosylase
PATSB16_RS10365	COG1214	PFAM Peptidase M22, glycoprotease
PATSB16_RS10370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PATSB16_RS10375	COG0765	amino acid transport
PATSB16_RS10380	COG0765	amino acid transport
PATSB16_RS10385	COG1126	abc transporter atp-binding protein
PATSB16_RS10390	COG5285	phytanoyl-CoA dioxygenase
PATSB16_RS10395	COG0662	Cupin 2, conserved barrel domain protein
PATSB16_RS10415	COG0513	Belongs to the DEAD box helicase family
PATSB16_RS10420	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PATSB16_RS10430	COG0583	DNA-binding transcription factor activity
PATSB16_RS10435	COG0589	response to stress
PATSB16_RS10440	COG2224	Isocitrate lyase
PATSB16_RS10445	COG0697	spore germination
PATSB16_RS10455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PATSB16_RS10460	COG0583	DNA-binding transcription factor activity
PATSB16_RS10485	COG0542	response to heat
PATSB16_RS10490	COG2346	COG2346, Truncated hemoglobins
PATSB16_RS10495	COG0314	molybdopterin synthase activity
PATSB16_RS10505	COG0303	'Molybdopterin
PATSB16_RS10510	COG1573	uracil-dna glycosylase
PATSB16_RS10525	COG0436	Aminotransferase
PATSB16_RS10540	COG2076	Multidrug Resistance protein
PATSB16_RS10545	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PATSB16_RS10550	COG0463	Glycosyl transferase, family 2
PATSB16_RS10565	COG0726	polysaccharide deacetylase
PATSB16_RS10570	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PATSB16_RS10575	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PATSB16_RS10580	COG0791	NLP P60 protein
PATSB16_RS10590	COG0359	binds to the 23S rRNA
PATSB16_RS10610	COG0583	DNA-binding transcription factor activity
PATSB16_RS10615	COG3960	tartronate-semialdehyde synthase activity
PATSB16_RS10620	COG3622	Belongs to the hyi family
PATSB16_RS10625	COG2084	Dehydrogenase
PATSB16_RS10635	COG3193	protein, possibly involved in utilization of glycolate and propanediol
PATSB16_RS10645	COG0252	asparaginase activity
PATSB16_RS10650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PATSB16_RS10660	COG1024	Enoyl-CoA hydratase
PATSB16_RS10665	COG1217	gtp-binding protein TYPA
PATSB16_RS10680	COG1566	PFAM secretion protein HlyD family protein
PATSB16_RS10685	COG2814	Major facilitator Superfamily
PATSB16_RS10690	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PATSB16_RS10700	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PATSB16_RS10705	COG2251	uridine kinase activity
PATSB16_RS10705	COG0195	Participates in both transcription termination and antitermination
PATSB16_RS10710	COG0779	Required for maturation of 30S ribosomal subunits
PATSB16_RS10715	COG1187	pseudouridine synthase activity
PATSB16_RS10720	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PATSB16_RS10725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PATSB16_RS10730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PATSB16_RS10750	COG1643	Atp-dependent helicase
PATSB16_RS10755	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PATSB16_RS10755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PATSB16_RS10760	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PATSB16_RS10770	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PATSB16_RS10780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PATSB16_RS10785	COG0557	exoribonuclease II activity
PATSB16_RS10800	COG0573	inorganic phosphate transmembrane transporter activity
PATSB16_RS10825	COG0066	3-isopropylmalate dehydratase activity
PATSB16_RS10830	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PATSB16_RS10835	COG0583	DNA-binding transcription factor activity
PATSB16_RS10840	COG2814	Major facilitator Superfamily
PATSB16_RS10865	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PATSB16_RS10890	COG0473	3-isopropylmalate dehydrogenase activity
PATSB16_RS10895	COG0583	DNA-binding transcription factor activity
PATSB16_RS10900	COG2755	lipolytic protein G-D-S-L family
PATSB16_RS10900	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PATSB16_RS10910	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PATSB16_RS10915	COG2818	Glycosylase
PATSB16_RS10920	COG0179	Fumarylacetoacetate (FAA) hydrolase
PATSB16_RS10935	COG0745	RESPONSE REGULATOR receiver
PATSB16_RS10940	COG0745	RESPONSE REGULATOR receiver
PATSB16_RS10960	COG2204	response regulator
PATSB16_RS10970	COG0174	glutamine synthetase
PATSB16_RS11050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PATSB16_RS11055	COG3395	kinase activity
PATSB16_RS11060	COG0235	Class ii aldolase
PATSB16_RS11065	COG0477	Major facilitator Superfamily
PATSB16_RS11100	COG2814	Major facilitator Superfamily
PATSB16_RS11130	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PATSB16_RS11135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PATSB16_RS11195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PATSB16_RS11245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PATSB16_RS11250	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PATSB16_RS11260	COG0183	Belongs to the thiolase family
PATSB16_RS11265	COG1414	Transcriptional regulator
PATSB16_RS11270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PATSB16_RS11305	COG0110	maltose O-acetyltransferase activity
PATSB16_RS11335	COG1335	isochorismatase
PATSB16_RS11380	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS11405	COG2207	Transcriptional regulator
PATSB16_RS11415	COG0477	Major facilitator Superfamily
PATSB16_RS11425	COG0235	Class ii aldolase
PATSB16_RS11435	COG1064	alcohol dehydrogenase
PATSB16_RS11440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PATSB16_RS11445	COG2015	COG2015, Alkyl sulfatase and related hydrolases
PATSB16_RS11460	COG0318	PFAM AMP-dependent synthetase and ligase
PATSB16_RS11465	COG0583	DNA-binding transcription factor activity
PATSB16_RS11470	COG2814	Major facilitator Superfamily
PATSB16_RS11475	COG0583	DNA-binding transcription factor activity
PATSB16_RS11500	COG0583	DNA-binding transcription factor activity
PATSB16_RS11515	COG0577	efflux transmembrane transporter activity
PATSB16_RS11515	COG1136	(ABC) transporter
PATSB16_RS11520	COG0577	efflux transmembrane transporter activity
PATSB16_RS11520	COG1136	(ABC) transporter
PATSB16_RS11550	COG0574	Belongs to the PEP-utilizing enzyme family
PATSB16_RS11550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PATSB16_RS11560	COG0058	SHG alpha-glucan phosphorylase activity
PATSB16_RS11590	COG0298	carbon dioxide binding
PATSB16_RS11595	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
PATSB16_RS11620	COG0543	2 iron, 2 sulfur cluster binding
PATSB16_RS11645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PATSB16_RS11650	COG1176	ABC-type spermidine putrescine transport system, permease component I
PATSB16_RS11665	COG0277	FAD linked oxidase domain protein
PATSB16_RS11675	COG4977	sequence-specific DNA binding
PATSB16_RS11710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PATSB16_RS11715	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PATSB16_RS11765	COG2204	response regulator
PATSB16_RS11775	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PATSB16_RS11795	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PATSB16_RS11800	COG1840	ABC-type Fe3 transport system, periplasmic component
PATSB16_RS11805	COG1752	Esterase of the alpha-beta hydrolase superfamily
PATSB16_RS11810	COG0791	NLP P60 protein
PATSB16_RS11815	COG4172	Belongs to the ABC transporter superfamily
PATSB16_RS11820	COG4239	(ABC) transporter, permease
PATSB16_RS11825	COG4174	ABC transporter (Permease)
PATSB16_RS11830	COG4166	transmembrane transport
PATSB16_RS11850	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS11855	COG4689	acetoacetate decarboxylase
PATSB16_RS11860	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PATSB16_RS11885	COG0583	DNA-binding transcription factor activity
PATSB16_RS11890	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PATSB16_RS11905	COG0527	aspartate kinase activity
PATSB16_RS11910	COG0037	tRNA processing
PATSB16_RS11915	COG0825	malonyl-CoA metabolic process
PATSB16_RS11920	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PATSB16_RS11925	COG0215	cysteine-tRNA ligase activity
PATSB16_RS11935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PATSB16_RS11940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PATSB16_RS11945	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PATSB16_RS11950	COG1045	serine acetyltransferase
PATSB16_RS11960	COG0483	inositol monophosphate 1-phosphatase activity
PATSB16_RS11970	COG4977	sequence-specific DNA binding
PATSB16_RS11975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PATSB16_RS12000	COG0285	dihydrofolate synthase activity
PATSB16_RS12005	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PATSB16_RS12010	COG0159	tryptophan synthase activity
PATSB16_RS12020	COG0133	tryptophan synthase activity
PATSB16_RS12025	COG0135	phosphoribosylanthranilate isomerase activity
PATSB16_RS12030	COG0101	tRNA pseudouridine synthase activity
PATSB16_RS12040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PATSB16_RS12045	COG0473	3-isopropylmalate dehydrogenase activity
PATSB16_RS12060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PATSB16_RS12065	COG0372	Belongs to the citrate synthase family
PATSB16_RS12070	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PATSB16_RS12075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PATSB16_RS12080	COG1053	succinate dehydrogenase
PATSB16_RS12085	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PATSB16_RS12110	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PATSB16_RS12120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PATSB16_RS12140	COG2866	Carboxypeptidase
PATSB16_RS12145	COG3022	response to hydroperoxide
PATSB16_RS12155	COG0436	Aminotransferase
PATSB16_RS12160	COG0625	glutathione transferase activity
PATSB16_RS12165	COG1250	3-hydroxyacyl-CoA dehydrogenase
PATSB16_RS12170	COG1024	Enoyl-CoA hydratase
PATSB16_RS12180	COG0625	glutathione transferase activity
PATSB16_RS12185	COG3422	double-strand break repair
PATSB16_RS12210	COG1007	ATP synthesis coupled electron transport
PATSB16_RS12225	COG0713	ATP synthesis coupled electron transport
PATSB16_RS12235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PATSB16_RS12240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PATSB16_RS12245	COG1034	ATP synthesis coupled electron transport
PATSB16_RS12260	COG0649	NAD binding
PATSB16_RS12265	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PATSB16_RS12270	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PATSB16_RS12275	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PATSB16_RS12290	COG0149	triose-phosphate isomerase activity
PATSB16_RS12300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PATSB16_RS12305	COG0251	oxidation-reduction process
PATSB16_RS12330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PATSB16_RS12335	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS12345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PATSB16_RS12350	COG0477	Major facilitator Superfamily
PATSB16_RS12365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PATSB16_RS12375	COG1295	ribonuclease BN
PATSB16_RS12390	COG0277	FAD linked oxidase domain protein
PATSB16_RS12395	COG0254	rRNA binding
PATSB16_RS12405	COG0534	Mate efflux family protein
PATSB16_RS12440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PATSB16_RS12450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PATSB16_RS12455	COG2081	HI0933 family
PATSB16_RS12460	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PATSB16_RS12465	COG1469	GTP cyclohydrolase I activity
PATSB16_RS12475	COG0142	geranyltranstransferase activity
PATSB16_RS12480	COG1722	exodeoxyribonuclease VII activity
PATSB16_RS12495	COG1252	NADH dehydrogenase
PATSB16_RS12505	COG1611	Belongs to the LOG family
PATSB16_RS12515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PATSB16_RS12525	COG0210	DNA helicase
PATSB16_RS12530	COG0525	valine-tRNA ligase activity
PATSB16_RS12535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PATSB16_RS12540	COG0425	Belongs to the sulfur carrier protein TusA family
PATSB16_RS12560	COG1942	4-Oxalocrotonate Tautomerase
PATSB16_RS12565	COG0235	Class ii aldolase
PATSB16_RS12570	COG0477	Major facilitator Superfamily
PATSB16_RS12580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PATSB16_RS12595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PATSB16_RS12655	COG4964	Belongs to the GSP D family
PATSB16_RS12690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PATSB16_RS12700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PATSB16_RS12705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PATSB16_RS12725	COG1178	ABC-type Fe3 transport system permease component
PATSB16_RS12735	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PATSB16_RS12770	COG0312	modulator of DNA gyrase
PATSB16_RS12775	COG3028	Belongs to the UPF0307 family
PATSB16_RS12780	COG0521	Mo-molybdopterin cofactor biosynthetic process
PATSB16_RS12800	COG2721	sulfolactate sulfo-lyase activity
PATSB16_RS12805	COG2721	sulfolactate sulfo-lyase activity
PATSB16_RS12810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PATSB16_RS12815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PATSB16_RS12840	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PATSB16_RS12845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PATSB16_RS12855	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
PATSB16_RS12860	COG1053	succinate dehydrogenase
PATSB16_RS12875	COG0501	Belongs to the peptidase M48B family
PATSB16_RS12880	COG1162	GTPase activity
PATSB16_RS12885	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PATSB16_RS12890	COG0494	nUDIX hydrolase
PATSB16_RS12895	COG0335	large ribosomal subunit rRNA binding
PATSB16_RS12900	COG0336	Belongs to the RNA methyltransferase TrmD family
PATSB16_RS12905	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PATSB16_RS12910	COG0228	four-way junction DNA binding
PATSB16_RS12925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PATSB16_RS12940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PATSB16_RS12945	COG0686	Belongs to the AlaDH PNT family
PATSB16_RS12950	COG1960	acyl-CoA dehydrogenase activity
PATSB16_RS12975	COG1024	Enoyl-CoA hydratase
PATSB16_RS12985	COG2951	lytic endotransglycosylase activity
PATSB16_RS13000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PATSB16_RS13005	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PATSB16_RS13015	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PATSB16_RS13025	COG0776	regulation of translation
PATSB16_RS13035	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PATSB16_RS13040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PATSB16_RS13045	COG0287	Prephenate dehydrogenase
PATSB16_RS13050	COG1605	Chorismate mutase
PATSB16_RS13050	COG0077	Prephenate dehydratase
PATSB16_RS13055	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PATSB16_RS13075	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PATSB16_RS13095	COG0697	spore germination
PATSB16_RS13120	COG1522	sequence-specific DNA binding
PATSB16_RS13130	COG5001	Diguanylate cyclase
PATSB16_RS13130	COG5002	protein histidine kinase activity
PATSB16_RS13160	COG1132	(ABC) transporter
PATSB16_RS13165	COG0189	ligase activity
PATSB16_RS13165	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PATSB16_RS13170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PATSB16_RS13170	COG0189	ligase activity
PATSB16_RS13195	COG0248	Ppx GppA phosphatase
PATSB16_RS13200	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PATSB16_RS13210	COG0745	RESPONSE REGULATOR receiver
PATSB16_RS13225	COG0581	inorganic phosphate transmembrane transporter activity
PATSB16_RS13230	COG0573	inorganic phosphate transmembrane transporter activity
PATSB16_RS13235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PATSB16_RS13240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PATSB16_RS13245	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PATSB16_RS13250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PATSB16_RS13260	COG1534	Rna-binding protein
PATSB16_RS13270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PATSB16_RS13275	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PATSB16_RS13285	COG0505	Belongs to the CarA family
PATSB16_RS13295	COG1301	dicarboxylic acid transport
PATSB16_RS13300	COG4266	Belongs to the allantoicase family
PATSB16_RS13325	COG1960	acyl-CoA dehydrogenase activity
PATSB16_RS13330	COG1024	Enoyl-CoA hydratase
PATSB16_RS13335	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS13350	COG0741	lytic transglycosylase activity
PATSB16_RS13350	COG1388	LysM domain
PATSB16_RS13355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PATSB16_RS13365	COG0328	RNA-DNA hybrid ribonuclease activity
PATSB16_RS13370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PATSB16_RS13380	COG1272	protein, Hemolysin III
PATSB16_RS13400	COG2814	Major facilitator Superfamily
PATSB16_RS13405	COG0010	Belongs to the arginase family
PATSB16_RS13410	COG1126	abc transporter atp-binding protein
PATSB16_RS13415	COG0765	amino acid transport
PATSB16_RS13420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PATSB16_RS13430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PATSB16_RS13450	COG2223	nitrite transmembrane transporter activity
PATSB16_RS13455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PATSB16_RS13465	COG0243	molybdopterin cofactor binding
PATSB16_RS13470	COG0583	DNA-binding transcription factor activity
PATSB16_RS13475	COG0625	glutathione transferase activity
PATSB16_RS13485	COG0587	DNA-directed DNA polymerase activity
PATSB16_RS13505	COG2252	PERMEase
PATSB16_RS13515	COG3021	interspecies interaction between organisms
PATSB16_RS13520	COG2217	Heavy metal translocating P-type atpase
PATSB16_RS13530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PATSB16_RS13530	COG4651	solute:proton antiporter activity
PATSB16_RS13560	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PATSB16_RS13565	COG0402	S-adenosylhomocysteine deaminase activity
PATSB16_RS13570	COG2119	membrane
PATSB16_RS13580	COG0308	aminopeptidase N
PATSB16_RS13590	COG0583	DNA-binding transcription factor activity
PATSB16_RS13595	COG0540	Belongs to the ATCase OTCase family
PATSB16_RS13615	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
PATSB16_RS13620	COG0582	viral genome integration into host DNA
PATSB16_RS13625	COG3093	addiction module antidote protein HigA
PATSB16_RS13635	COG2860	membrane
PATSB16_RS13650	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PATSB16_RS13660	COG0243	molybdopterin cofactor binding
PATSB16_RS13670	COG0179	Fumarylacetoacetate (FAA) hydrolase
PATSB16_RS13675	COG0657	acetylesterase activity
PATSB16_RS13680	COG0402	S-adenosylhomocysteine deaminase activity
PATSB16_RS13685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PATSB16_RS13700	COG0583	DNA-binding transcription factor activity
PATSB16_RS13720	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS13720	COG3321	synthase
PATSB16_RS13720	COG0604	alcohol dehydrogenase
PATSB16_RS13725	COG0431	NADPH-dependent FMN reductase
PATSB16_RS13755	COG1846	Transcriptional regulator
PATSB16_RS13765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PATSB16_RS13775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PATSB16_RS13780	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PATSB16_RS13785	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS13790	COG3958	Transketolase
PATSB16_RS13795	COG3959	Transketolase, thiamine diphosphate binding domain
PATSB16_RS13800	COG0583	DNA-binding transcription factor activity
PATSB16_RS13805	COG2200	EAL domain
PATSB16_RS13810	COG0678	peroxiredoxin activity
PATSB16_RS13815	COG2188	Transcriptional regulator
PATSB16_RS13820	COG2271	Major facilitator Superfamily
PATSB16_RS13860	COG2814	Major facilitator Superfamily
PATSB16_RS13875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PATSB16_RS13885	COG4521	taurine ABC transporter
PATSB16_RS13890	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PATSB16_RS13895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PATSB16_RS13900	COG2205	protein histidine kinase activity
PATSB16_RS13905	COG0745	RESPONSE REGULATOR receiver
PATSB16_RS13910	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PATSB16_RS13920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PATSB16_RS13945	COG1414	Transcriptional regulator
PATSB16_RS13955	COG1113	amino acid transport
PATSB16_RS13965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PATSB16_RS13970	COG1414	Transcriptional regulator
PATSB16_RS13980	COG0477	Major facilitator Superfamily
PATSB16_RS13985	COG1414	Transcriptional regulator
PATSB16_RS14005	COG1012	belongs to the aldehyde dehydrogenase family
PATSB16_RS14010	COG0318	PFAM AMP-dependent synthetase and ligase
PATSB16_RS14015	COG2271	Major facilitator Superfamily
PATSB16_RS14020	COG2084	Dehydrogenase
PATSB16_RS14025	COG0824	Thioesterase
PATSB16_RS14035	COG0848	biopolymer transport protein
PATSB16_RS14045	COG0823	Involved in the tonB-independent uptake of proteins
PATSB16_RS14050	COG2885	chlorophyll binding
PATSB16_RS14055	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PATSB16_RS14065	COG1968	undecaprenyl-diphosphatase activity
PATSB16_RS14070	COG2252	PERMEase
PATSB16_RS14080	COG3387	PFAM Glycoside hydrolase 15-related
PATSB16_RS14085	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PATSB16_RS14140	COG4789	Type iii secretion
PATSB16_RS14170	COG0076	glutamate decarboxylase activity
PATSB16_RS14190	COG3033	Beta-eliminating lyase
PATSB16_RS14195	COG3300	MHYT domain
PATSB16_RS14195	COG5001	Diguanylate cyclase
PATSB16_RS14205	COG2909	trisaccharide binding
PATSB16_RS14230	COG2814	Major facilitator Superfamily
PATSB16_RS14235	COG1522	sequence-specific DNA binding
PATSB16_RS14240	COG2423	ornithine cyclodeaminase activity
PATSB16_RS14265	COG1999	signal sequence binding
PATSB16_RS14300	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PATSB16_RS14305	COG0438	transferase activity, transferring glycosyl groups
PATSB16_RS14325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PATSB16_RS14350	COG0438	transferase activity, transferring glycosyl groups
PATSB16_RS14365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PATSB16_RS14375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PATSB16_RS14380	COG2153	protein acetylation
PATSB16_RS14385	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PATSB16_RS14385	COG0662	Cupin 2, conserved barrel domain protein
PATSB16_RS14390	COG2814	Major facilitator Superfamily
PATSB16_RS14420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PATSB16_RS14425	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
PATSB16_RS14435	COG1473	amidohydrolase
PATSB16_RS14440	COG0583	DNA-binding transcription factor activity
PATSB16_RS14485	COG1012	belongs to the aldehyde dehydrogenase family
PATSB16_RS14495	COG0028	Belongs to the TPP enzyme family
PATSB16_RS14500	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS14505	COG1414	Transcriptional regulator
PATSB16_RS14520	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS14525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PATSB16_RS14535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PATSB16_RS14540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PATSB16_RS14550	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PATSB16_RS14580	COG0322	excinuclease ABC activity
PATSB16_RS14590	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PATSB16_RS14595	COG2204	response regulator
PATSB16_RS14605	COG0736	holo-[acyl-carrier-protein] synthase activity
PATSB16_RS14610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PATSB16_RS14620	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PATSB16_RS14625	COG0571	ribonuclease III activity
PATSB16_RS14630	COG0681	Belongs to the peptidase S26 family
PATSB16_RS14645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PATSB16_RS14670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PATSB16_RS14675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PATSB16_RS14680	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS14690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PATSB16_RS14695	COG0416	fatty acid biosynthetic process
PATSB16_RS14700	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PATSB16_RS14705	COG1399	metal-binding, possibly nucleic acid-binding protein
PATSB16_RS14710	COG0424	maF-like protein
PATSB16_RS14720	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PATSB16_RS14720	COG0616	signal peptide processing
PATSB16_RS14730	COG0546	phosphoglycolate phosphatase activity
PATSB16_RS14735	COG0564	pseudouridine synthase activity
PATSB16_RS14740	COG1530	ribonuclease E activity
PATSB16_RS14745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PATSB16_RS14750	COG0746	molybdenum cofactor guanylyltransferase activity
PATSB16_RS14755	COG0303	'Molybdopterin
PATSB16_RS14765	COG0456	acetyltransferase
PATSB16_RS14770	COG1322	Protein conserved in bacteria
PATSB16_RS14805	COG0579	oxidoreductase
PATSB16_RS14815	COG3384	dioxygenase
PATSB16_RS14825	COG1280	lysine exporter protein (LysE YggA)
PATSB16_RS14835	COG1278	Cold shock
PATSB16_RS14845	COG2943	transferase activity, transferring hexosyl groups
PATSB16_RS14845	COG3416	Protein conserved in bacteria
PATSB16_RS14850	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PATSB16_RS14860	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PATSB16_RS14865	COG0251	oxidation-reduction process
PATSB16_RS14890	COG0235	Class ii aldolase
PATSB16_RS14895	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PATSB16_RS14905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PATSB16_RS14910	COG1126	abc transporter atp-binding protein
PATSB16_RS14915	COG0765	amino acid transport
PATSB16_RS14920	COG0765	amino acid transport
PATSB16_RS14950	COG0411	ABC transporter
PATSB16_RS14980	COG0583	DNA-binding transcription factor activity
PATSB16_RS14985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PATSB16_RS14990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PATSB16_RS14995	COG0765	amino acid transport
PATSB16_RS15000	COG1126	abc transporter atp-binding protein
PATSB16_RS15025	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PATSB16_RS15035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PATSB16_RS15040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PATSB16_RS15040	COG0425	Belongs to the sulfur carrier protein TusA family
PATSB16_RS15055	COG0859	PFAM glycosyl transferase family 9
PATSB16_RS15070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PATSB16_RS15080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PATSB16_RS15085	COG0438	transferase activity, transferring glycosyl groups
PATSB16_RS15145	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PATSB16_RS15165	COG0540	Belongs to the ATCase OTCase family
PATSB16_RS15170	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PATSB16_RS15175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PATSB16_RS15180	COG1678	Uncharacterized ACR, COG1678
PATSB16_RS15190	COG1773	rubredoxin
PATSB16_RS15195	COG0351	phosphomethylpyrimidine kinase
PATSB16_RS15200	COG3307	-O-antigen
PATSB16_RS15205	COG4969	Belongs to the N-Me-Phe pilin family
PATSB16_RS15210	COG0861	Integral membrane protein TerC family
PATSB16_RS15215	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PATSB16_RS15220	COG0045	succinate-CoA ligase (ADP-forming) activity
PATSB16_RS15230	COG2137	regulation of response to DNA damage stimulus
PATSB16_RS15235	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PATSB16_RS15250	COG0477	Major facilitator Superfamily
PATSB16_RS15295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PATSB16_RS15305	COG1396	sequence-specific DNA binding
PATSB16_RS15315	COG2271	Major facilitator Superfamily
PATSB16_RS15320	COG1902	pentaerythritol trinitrate reductase activity
PATSB16_RS15325	COG0668	transmembrane transport
PATSB16_RS15355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PATSB16_RS15380	COG2719	SpoVR family
PATSB16_RS15385	COG2718	Belongs to the UPF0229 family
PATSB16_RS15390	COG2766	serine protein kinase
PATSB16_RS15395	COG0803	Belongs to the bacterial solute-binding protein 9 family
PATSB16_RS15400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PATSB16_RS15405	COG1702	phosphate starvation-inducible protein PhoH
PATSB16_RS15410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PATSB16_RS15415	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
PATSB16_RS15425	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PATSB16_RS15430	COG0752	glycyl-tRNA synthetase alpha subunit
PATSB16_RS15435	COG0751	glycine-tRNA ligase activity
PATSB16_RS15440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PATSB16_RS15445	COG0204	Acyl-transferase
PATSB16_RS15455	COG0346	lactoylglutathione lyase activity
PATSB16_RS15470	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PATSB16_RS15475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PATSB16_RS15480	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PATSB16_RS15490	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PATSB16_RS15495	COG0006	proline dipeptidase activity
PATSB16_RS15500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PATSB16_RS15505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PATSB16_RS15510	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
PATSB16_RS15515	COG0138	bifunctional purine biosynthesis protein purh
PATSB16_RS15520	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PATSB16_RS15540	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PATSB16_RS15545	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PATSB16_RS15550	COG0735	belongs to the Fur family
PATSB16_RS15555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PATSB16_RS15560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PATSB16_RS15565	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PATSB16_RS15575	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PATSB16_RS15595	COG0280	phosphate acetyltransferase
PATSB16_RS15595	COG0281	malic enzyme
PATSB16_RS15605	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PATSB16_RS15610	COG1058	Belongs to the CinA family
PATSB16_RS15610	COG1546	Belongs to the CinA family
PATSB16_RS15615	COG0284	orotidine-5'-phosphate decarboxylase activity
PATSB16_RS15620	COG0668	transmembrane transport
PATSB16_RS15625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PATSB16_RS15630	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PATSB16_RS15640	COG0557	exoribonuclease II activity
PATSB16_RS15650	COG1881	PFAM PEBP family protein
PATSB16_RS15655	COG1490	D-aminoacyl-tRNA deacylase activity
PATSB16_RS15670	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PATSB16_RS15680	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PATSB16_RS15685	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PATSB16_RS15705	COG0418	dihydroorotase activity
PATSB16_RS15710	COG0121	glutamine amidotransferase
PATSB16_RS15715	COG1126	abc transporter atp-binding protein
PATSB16_RS15720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PATSB16_RS15725	COG0583	DNA-binding transcription factor activity
PATSB16_RS15730	COG5265	(ABC) transporter
PATSB16_RS15745	COG0183	Belongs to the thiolase family
PATSB16_RS15750	COG1024	Enoyl-CoA hydratase
PATSB16_RS15750	COG1250	3-hydroxyacyl-CoA dehydrogenase
PATSB16_RS15755	COG1960	acyl-CoA dehydrogenase activity
PATSB16_RS15765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PATSB16_RS15770	COG0494	nUDIX hydrolase
PATSB16_RS15795	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PATSB16_RS15810	COG2226	methyltransferase
PATSB16_RS15825	COG0025	NhaP-type Na H and K H
PATSB16_RS15845	COG1238	metal cluster binding
PATSB16_RS15865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PATSB16_RS15885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PATSB16_RS15895	COG1012	belongs to the aldehyde dehydrogenase family
PATSB16_RS15900	COG3284	Transcriptional regulator
PATSB16_RS15905	COG0596	Alpha beta hydrolase
PATSB16_RS15915	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PATSB16_RS15920	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
PATSB16_RS15930	COG0535	radical SAM domain protein
PATSB16_RS15955	COG1846	Transcriptional regulator
PATSB16_RS15970	COG2902	Dehydrogenase
PATSB16_RS15990	COG0656	L-ascorbic acid biosynthetic process
PATSB16_RS16015	COG3344	reverse transcriptase
PATSB16_RS16040	COG2233	PERMEase
PATSB16_RS16070	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS16075	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PATSB16_RS16090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PATSB16_RS16095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PATSB16_RS16100	COG1609	Transcriptional regulator
PATSB16_RS16105	COG0629	single-stranded DNA binding
PATSB16_RS16110	COG2814	Major facilitator Superfamily
PATSB16_RS16130	COG1283	sodium-dependent phosphate transmembrane transporter activity
PATSB16_RS16135	COG1012	belongs to the aldehyde dehydrogenase family
PATSB16_RS16170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PATSB16_RS16195	COG0583	DNA-binding transcription factor activity
PATSB16_RS16205	COG1280	lysine exporter protein (LysE YggA)
PATSB16_RS16210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PATSB16_RS16240	COG1137	ATPase activity
PATSB16_RS16245	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PATSB16_RS16250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PATSB16_RS16260	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PATSB16_RS16270	COG1660	Displays ATPase and GTPase activities
PATSB16_RS16275	COG1194	a g-specific adenine glycosylase
PATSB16_RS16280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PATSB16_RS16290	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PATSB16_RS16305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PATSB16_RS16315	COG0193	aminoacyl-tRNA hydrolase activity
PATSB16_RS16320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PATSB16_RS16325	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PATSB16_RS16330	COG0742	ribosomal rna small subunit methyltransferase
PATSB16_RS16335	COG1131	(ABC) transporter
PATSB16_RS16345	COG0612	Peptidase, M16
PATSB16_RS16350	COG0612	Peptidase, M16
PATSB16_RS16360	COG0625	glutathione transferase activity
PATSB16_RS16370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PATSB16_RS16380	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PATSB16_RS16400	COG1294	oxidase, subunit
PATSB16_RS16410	COG0109	protoheme IX farnesyltransferase activity
PATSB16_RS16415	COG1612	heme a metabolic process
PATSB16_RS16445	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PATSB16_RS16450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PATSB16_RS16465	COG2226	methyltransferase
PATSB16_RS16485	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PATSB16_RS16490	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PATSB16_RS16495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PATSB16_RS16505	COG0793	Belongs to the peptidase S41A family
PATSB16_RS16515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PATSB16_RS16520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PATSB16_RS16530	COG0189	ligase activity
PATSB16_RS16545	COG0004	ammonium transporteR
PATSB16_RS16550	COG0347	Belongs to the P(II) protein family
PATSB16_RS16560	COG2960	long-chain fatty acid transporting porin activity
PATSB16_RS16575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PATSB16_RS16585	COG0859	PFAM glycosyl transferase family 9
PATSB16_RS16595	COG0321	lipoyl(octanoyl) transferase activity
PATSB16_RS16605	COG0583	DNA-binding transcription factor activity
PATSB16_RS16610	COG2921	Belongs to the UPF0250 family
PATSB16_RS16615	COG1686	Belongs to the peptidase S11 family
PATSB16_RS16640	COG1127	ABC transporter
PATSB16_RS16645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PATSB16_RS16650	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PATSB16_RS16650	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PATSB16_RS16670	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PATSB16_RS16695	COG1024	Enoyl-CoA hydratase
PATSB16_RS16740	COG1410	methionine synthase
PATSB16_RS16740	COG0646	methionine synthase
PATSB16_RS16770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PATSB16_RS16775	COG0300	oxidoreductase activity
PATSB16_RS16790	COG0789	Transcriptional regulator
PATSB16_RS16800	COG1960	acyl-CoA dehydrogenase activity
PATSB16_RS16805	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PATSB16_RS16810	COG0288	reversible hydration of carbon dioxide
PATSB16_RS16815	COG0183	Belongs to the thiolase family
PATSB16_RS16820	COG1960	acyl-CoA dehydrogenase activity
PATSB16_RS16830	COG3012	SEC-C Motif Domain Protein
PATSB16_RS16835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PATSB16_RS16840	COG1024	Enoyl-CoA hydratase
PATSB16_RS16850	COG0156	8-amino-7-oxononanoate synthase activity
PATSB16_RS16860	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PATSB16_RS16885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PATSB16_RS16920	COG3706	GGDEF domain
PATSB16_RS16930	COG0596	Alpha beta hydrolase
PATSB16_RS16965	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
PATSB16_RS16970	COG1733	regulation of RNA biosynthetic process
PATSB16_RS16980	COG1250	3-hydroxyacyl-CoA dehydrogenase
PATSB16_RS16985	COG1703	isobutyryl-CoA mutase activity
PATSB16_RS16985	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PATSB16_RS16985	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PATSB16_RS17000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PATSB16_RS17005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PATSB16_RS17025	COG1024	Enoyl-CoA hydratase
PATSB16_RS17035	COG1309	transcriptional regulator
PATSB16_RS17065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PATSB16_RS17070	COG1131	(ABC) transporter
PATSB16_RS17075	COG0842	Transport permease protein
PATSB16_RS17085	COG1739	Uncharacterized protein family UPF0029
PATSB16_RS17090	COG0322	excinuclease ABC activity
PATSB16_RS17105	COG1562	ergosterol biosynthetic process
PATSB16_RS17110	COG1741	Belongs to the pirin family
PATSB16_RS17120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PATSB16_RS17125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PATSB16_RS17130	COG0583	DNA-binding transcription factor activity
PATSB16_RS17145	COG0586	Pfam SNARE associated Golgi protein
PATSB16_RS17165	COG1802	Transcriptional regulator
PATSB16_RS17170	COG1024	Enoyl-CoA hydratase
PATSB16_RS17175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PATSB16_RS17185	COG0247	lactate metabolic process
PATSB16_RS17185	COG0277	FAD linked oxidase domain protein
PATSB16_RS17195	COG2271	Major facilitator Superfamily
PATSB16_RS17200	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PATSB16_RS17205	COG1802	Transcriptional regulator
PATSB16_RS17210	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
PATSB16_RS17215	COG1234	tRNA 3'-trailer cleavage
PATSB16_RS17225	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PATSB16_RS17230	COG3473	Maleate cis-trans isomerase
PATSB16_RS17250	COG1021	2,3-dihydroxybenzoate-AMP ligase
PATSB16_RS17280	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PATSB16_RS17285	COG0625	glutathione transferase activity
PATSB16_RS17310	COG2814	Major facilitator Superfamily
PATSB16_RS17315	COG1846	Transcriptional regulator
PATSB16_RS17350	COG0300	oxidoreductase activity
PATSB16_RS17365	COG3311	Transcriptional regulator
PATSB16_RS17390	COG1280	lysine exporter protein (LysE YggA)
PATSB16_RS17400	COG4521	taurine ABC transporter
PATSB16_RS17440	COG1522	sequence-specific DNA binding
PATSB16_RS17445	COG1280	lysine exporter protein (LysE YggA)
PATSB16_RS17455	COG2207	Transcriptional regulator
PATSB16_RS17455	COG1917	Cupin 2, conserved barrel domain protein
PATSB16_RS17495	COG0410	ABC transporter
PATSB16_RS17500	COG0154	amidase activity
PATSB16_RS17510	COG1396	sequence-specific DNA binding
PATSB16_RS17525	COG2337	Toxic component of a toxin-antitoxin (TA) module
PATSB16_RS17535	COG0697	spore germination
PATSB16_RS17555	COG0477	Major facilitator Superfamily
PATSB16_RS17570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PATSB16_RS17575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PATSB16_RS17585	COG0583	DNA-binding transcription factor activity
PATSB16_RS17600	COG0415	Belongs to the DNA photolyase family
PATSB16_RS17610	COG0415	Belongs to the DNA photolyase family
PATSB16_RS17615	COG3046	protein related to deoxyribodipyrimidine photolyase
PATSB16_RS17645	COG0596	Alpha beta hydrolase
PATSB16_RS17655	COG1024	Enoyl-CoA hydratase
PATSB16_RS17665	COG1414	Transcriptional regulator
PATSB16_RS17675	COG0765	amino acid transport
PATSB16_RS17680	COG0765	amino acid transport
PATSB16_RS17690	COG1126	abc transporter atp-binding protein
PATSB16_RS17700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PATSB16_RS17705	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PATSB16_RS17715	COG0642	Histidine kinase
PATSB16_RS17720	COG1902	pentaerythritol trinitrate reductase activity
PATSB16_RS17720	COG0446	pyridine nucleotide-disulphide oxidoreductase
PATSB16_RS17740	COG0517	IMP dehydrogenase activity
PATSB16_RS17770	COG0583	DNA-binding transcription factor activity
PATSB16_RS17790	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS17795	COG0625	glutathione transferase activity
PATSB16_RS17800	COG0625	glutathione transferase activity
PATSB16_RS17825	COG5611	PilT protein domain protein
PATSB16_RS17830	COG2271	Major facilitator Superfamily
PATSB16_RS17845	COG0583	DNA-binding transcription factor activity
PATSB16_RS17850	COG2862	Uncharacterized protein family, UPF0114
PATSB16_RS17855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PATSB16_RS17860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PATSB16_RS17870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PATSB16_RS17875	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS17895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PATSB16_RS17900	COG3246	L-lysine catabolic process to acetate
PATSB16_RS17910	COG0617	tRNA 3'-terminal CCA addition
PATSB16_RS17925	COG0741	lytic transglycosylase activity
PATSB16_RS17930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PATSB16_RS17940	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PATSB16_RS17945	COG1984	allophanate hydrolase subunit 2
PATSB16_RS17950	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PATSB16_RS17960	COG0583	DNA-binding transcription factor activity
PATSB16_RS17965	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PATSB16_RS17975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PATSB16_RS17980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PATSB16_RS18000	COG0411	ABC transporter
PATSB16_RS18005	COG0410	ABC transporter
PATSB16_RS18015	COG0831	urea catabolic process
PATSB16_RS18020	COG0832	Belongs to the urease beta subunit family
PATSB16_RS18035	COG0830	nickel cation binding
PATSB16_RS18040	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PATSB16_RS18050	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PATSB16_RS18055	COG1950	PFAM Membrane protein of
PATSB16_RS18060	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PATSB16_RS18065	COG0708	Exodeoxyribonuclease III
PATSB16_RS18070	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS18075	COG0667	Aldo Keto reductase
PATSB16_RS18080	COG0583	DNA-binding transcription factor activity
PATSB16_RS18085	COG2329	Antibiotic biosynthesis monooxygenase
PATSB16_RS18100	COG0400	carboxylic ester hydrolase activity
PATSB16_RS18105	COG2814	Major facilitator Superfamily
PATSB16_RS18110	COG2813	Specifically methylates the guanine in position
PATSB16_RS18110	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PATSB16_RS18115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PATSB16_RS18120	COG1309	transcriptional regulator
PATSB16_RS18135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PATSB16_RS18140	COG1595	DNA-templated transcription, initiation
PATSB16_RS18165	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PATSB16_RS18175	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PATSB16_RS18180	COG3344	reverse transcriptase
PATSB16_RS18195	COG0523	cobalamin synthesis protein
PATSB16_RS18205	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PATSB16_RS18210	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PATSB16_RS18220	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PATSB16_RS18225	COG1560	Kdo2-lipid A biosynthetic process
PATSB16_RS18230	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PATSB16_RS18240	COG1960	acyl-CoA dehydrogenase activity
PATSB16_RS18260	COG0154	amidase activity
PATSB16_RS18265	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PATSB16_RS18270	COG1077	Cell shape determining protein MreB Mrl
PATSB16_RS18275	COG1792	Involved in formation and maintenance of cell shape
PATSB16_RS18285	COG0768	penicillin binding
PATSB16_RS18290	COG0772	Belongs to the SEDS family
PATSB16_RS18300	COG0720	synthase
PATSB16_RS18305	COG0602	queuosine metabolic process
PATSB16_RS18310	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PATSB16_RS18320	COG2204	response regulator
PATSB16_RS18320	COG2204	response regulator
PATSB16_RS18325	COG5000	phosphorelay sensor kinase activity
PATSB16_RS18340	COG0501	Belongs to the peptidase M48B family
PATSB16_RS18345	COG1280	lysine exporter protein (LysE YggA)
PATSB16_RS18350	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PATSB16_RS18355	COG0242	peptide deformylase activity
PATSB16_RS18360	COG0758	DNA mediated transformation
PATSB16_RS18360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PATSB16_RS18385	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
PATSB16_RS18390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PATSB16_RS18420	COG5001	Diguanylate cyclase
PATSB16_RS18420	COG1716	ATPase activity
PATSB16_RS18425	COG2223	nitrite transmembrane transporter activity
PATSB16_RS18455	COG2814	Major facilitator Superfamily
PATSB16_RS18465	COG0531	amino acid
PATSB16_RS18480	COG0842	Transport permease protein
PATSB16_RS18485	COG1131	(ABC) transporter
PATSB16_RS18495	COG0583	DNA-binding transcription factor activity
PATSB16_RS18500	COG0583	DNA-binding transcription factor activity
PATSB16_RS18505	COG1960	acyl-CoA dehydrogenase activity
PATSB16_RS18510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PATSB16_RS18515	COG0477	Major facilitator Superfamily
PATSB16_RS18520	COG1522	sequence-specific DNA binding
PATSB16_RS18530	COG0626	cystathionine gamma-synthase activity
PATSB16_RS18535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PATSB16_RS18540	COG0765	amino acid transport
PATSB16_RS18545	COG1126	abc transporter atp-binding protein
PATSB16_RS18570	COG0583	DNA-binding transcription factor activity
PATSB16_RS18595	COG0405	Gamma-glutamyltransferase
PATSB16_RS18600	COG1177	transmembrane transport
PATSB16_RS18605	COG1176	ABC-type spermidine putrescine transport system, permease component I
PATSB16_RS18610	COG3842	ATPase activity
PATSB16_RS18620	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PATSB16_RS18625	COG2186	Transcriptional regulator
PATSB16_RS18645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PATSB16_RS18650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PATSB16_RS18670	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PATSB16_RS18675	COG2733	membrane
PATSB16_RS18690	COG2200	EAL domain
PATSB16_RS18690	COG2199	diguanylate cyclase activity
PATSB16_RS18690	COG3287	FIST C domain
PATSB16_RS18710	COG1201	RNA secondary structure unwinding
PATSB16_RS18740	COG0514	ATP-dependent DNA helicase (RecQ)
PATSB16_RS18745	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PATSB16_RS18760	COG4372	Transposase
PATSB16_RS18780	COG0720	synthase
PATSB16_RS18820	COG3550	peptidyl-serine autophosphorylation
PATSB16_RS18845	COG0592	DNA-directed DNA polymerase activity
PATSB16_RS18850	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PATSB16_RS18855	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PATSB16_RS18860	COG0594	ribonuclease P activity
PATSB16_RS18870	COG0706	membrane insertase activity
PATSB16_RS18875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PATSB16_RS18880	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PATSB16_RS18890	COG2814	Major facilitator Superfamily
PATSB16_RS18900	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PATSB16_RS18900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PATSB16_RS18935	COG2154	pterin-4-alpha-carbinolamine dehydratase
PATSB16_RS18950	COG2423	ornithine cyclodeaminase activity
PATSB16_RS18955	COG0583	DNA-binding transcription factor activity
PATSB16_RS18965	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS18970	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PATSB16_RS18985	COG1473	amidohydrolase
PATSB16_RS18990	COG1802	Transcriptional regulator
PATSB16_RS18995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PATSB16_RS19010	COG0367	asparagine synthase
PATSB16_RS19015	COG1522	sequence-specific DNA binding
PATSB16_RS19025	COG0114	fumarate hydratase activity
PATSB16_RS19030	COG0583	DNA-binding transcription factor activity
PATSB16_RS19060	COG0559	Belongs to the binding-protein-dependent transport system permease family
PATSB16_RS19065	COG1172	Belongs to the binding-protein-dependent transport system permease family
PATSB16_RS19075	COG1846	Transcriptional regulator
PATSB16_RS19095	COG2070	2-Nitropropane dioxygenase
PATSB16_RS19100	COG0445	tRNA wobble uridine modification
PATSB16_RS19115	COG1192	Involved in chromosome partitioning
PATSB16_RS19120	COG1475	DNA binding
PATSB16_RS19125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PATSB16_RS19135	COG0356	it plays a direct role in the translocation of protons across the membrane
PATSB16_RS19145	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PATSB16_RS19150	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PATSB16_RS19160	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PATSB16_RS19165	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PATSB16_RS19170	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PATSB16_RS19185	COG0318	PFAM AMP-dependent synthetase and ligase
PATSB16_RS19205	COG1360	Flagellar Motor Protein
PATSB16_RS19210	COG0745	RESPONSE REGULATOR receiver
PATSB16_RS19215	COG0643	Histidine kinase
PATSB16_RS19215	COG2198	Histidine kinase
PATSB16_RS19220	COG0835	chemotaxis
PATSB16_RS19225	COG0840	transmembrane signaling receptor activity
PATSB16_RS19225	COG0840	transmembrane signaling receptor activity
PATSB16_RS19230	COG0840	transmembrane signaling receptor activity
PATSB16_RS19240	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PATSB16_RS19245	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PATSB16_RS19255	COG0745	RESPONSE REGULATOR receiver
PATSB16_RS19260	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PATSB16_RS19265	COG0667	Aldo Keto reductase
PATSB16_RS19270	COG0583	DNA-binding transcription factor activity
PATSB16_RS19280	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PATSB16_RS19295	COG1191	sigma factor activity
PATSB16_RS19320	COG1558	bacterial-type flagellum-dependent cell motility
PATSB16_RS19335	COG4787	bacterial-type flagellum-dependent cell motility
PATSB16_RS19345	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PATSB16_RS19350	COG1706	bacterial-type flagellum-dependent cell motility
PATSB16_RS19355	COG3951	Flagellar rod assembly protein muramidase FlgJ
PATSB16_RS19355	COG1705	Flagellar rod assembly protein muramidase FlgJ
PATSB16_RS19360	COG1256	bacterial-type flagellum assembly
PATSB16_RS19380	COG1338	Plays a role in the flagellum-specific transport system
PATSB16_RS19385	COG3190	flagellar
PATSB16_RS19400	COG1580	Controls the rotational direction of flagella during chemotaxis
PATSB16_RS19435	COG1677	Flagellar hook-basal body complex protein FliE
PATSB16_RS19440	COG2257	FlhB HrpN YscU SpaS Family
PATSB16_RS19460	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PATSB16_RS19500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PATSB16_RS19520	COG2828	Protein conserved in bacteria
PATSB16_RS19535	COG3245	cytochrome
PATSB16_RS19540	COG0210	DNA helicase
PATSB16_RS19555	COG0509	glycine decarboxylation via glycine cleavage system
PATSB16_RS19560	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PATSB16_RS19560	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PATSB16_RS19565	COG1760	l-serine dehydratase
PATSB16_RS19575	COG1012	belongs to the aldehyde dehydrogenase family
PATSB16_RS19580	COG0028	Belongs to the TPP enzyme family
PATSB16_RS19585	COG0583	DNA-binding transcription factor activity
PATSB16_RS19590	COG0477	Major facilitator Superfamily
PATSB16_RS19600	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PATSB16_RS19600	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PATSB16_RS19600	COG0506	proline dehydrogenase activity
PATSB16_RS19605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PATSB16_RS19620	COG0657	acetylesterase activity
PATSB16_RS19625	COG1832	CoA-binding protein
PATSB16_RS19630	COG3622	Belongs to the hyi family
PATSB16_RS19655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PATSB16_RS19665	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PATSB16_RS19670	COG0792	nuclease activity
PATSB16_RS19675	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PATSB16_RS19680	COG2823	Periplasmic or secreted lipoprotein
PATSB16_RS19695	COG3047	cAMP biosynthetic process
PATSB16_RS19725	COG0583	DNA-binding transcription factor activity
PATSB16_RS19735	COG1028	Short-chain dehydrogenase reductase Sdr
PATSB16_RS19740	COG0443	Heat shock 70 kDa protein
PATSB16_RS19745	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
PATSB16_RS19750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PATSB16_RS19765	COG2233	PERMEase
PATSB16_RS19770	COG0513	Belongs to the DEAD box helicase family
PATSB16_RS19775	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PATSB16_RS19790	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PATSB16_RS19795	COG1763	Mo-molybdopterin cofactor biosynthetic process
PATSB16_RS19800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PATSB16_RS19805	COG2814	Major facilitator Superfamily
PATSB16_RS19810	COG0281	malic enzyme
PATSB16_RS19810	COG0280	phosphate acetyltransferase
PATSB16_RS19830	COG1522	sequence-specific DNA binding
PATSB16_RS19855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PATSB16_RS19860	COG2151	metal-sulfur cluster biosynthetic enzyme
PATSB16_RS19865	COG3396	Phenylacetate-CoA oxygenase
PATSB16_RS19870	COG3460	Phenylacetate-CoA oxygenase
PATSB16_RS19875	COG3396	Phenylacetate-CoA oxygenase
PATSB16_RS19930	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PATSB16_RS19945	COG0081	regulation of translation
PATSB16_RS19955	COG0222	ribosome binding
PATSB16_RS19960	COG0085	RNA polymerase activity
PATSB16_RS19970	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PATSB16_RS19975	COG0049	tRNA binding
PATSB16_RS19990	COG0051	transcription antitermination factor activity, RNA binding
PATSB16_RS19995	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PATSB16_RS20005	COG0089	rRNA binding
PATSB16_RS20010	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PATSB16_RS20020	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PATSB16_RS20025	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PATSB16_RS20030	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PATSB16_RS20035	COG0255	Belongs to the universal ribosomal protein uL29 family
PATSB16_RS20040	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PATSB16_RS20045	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PATSB16_RS20050	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PATSB16_RS20055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PATSB16_RS20070	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PATSB16_RS20075	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PATSB16_RS20080	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PATSB16_RS20090	COG0200	Binds to the 23S rRNA
PATSB16_RS20095	COG0201	protein transport
PATSB16_RS20105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PATSB16_RS20110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PATSB16_RS20115	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PATSB16_RS20120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PATSB16_RS20125	COG0202	RNA polymerase activity
PATSB16_RS20140	COG4232	protein-disulfide reductase activity
PATSB16_RS20150	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PATSB16_RS20160	COG1333	cytochrome c biogenesis protein
PATSB16_RS20165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PATSB16_RS20170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PATSB16_RS20175	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PATSB16_RS20190	COG1965	Belongs to the frataxin family
PATSB16_RS20230	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PATSB16_RS20235	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PATSB16_RS20240	COG4575	ribosome binding
PATSB16_RS20245	COG3047	cAMP biosynthetic process
PATSB16_RS20250	COG3047	cAMP biosynthetic process
PATSB16_RS20260	COG0070	glutamate synthase
PATSB16_RS20260	COG0069	glutamate synthase activity
PATSB16_RS20260	COG0067	glutamate synthase
PATSB16_RS20270	COG4178	(ABC) transporter
PATSB16_RS20295	COG1127	ABC transporter
PATSB16_RS20300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PATSB16_RS20305	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PATSB16_RS20310	COG2853	Lipoprotein
PATSB16_RS20325	COG1131	(ABC) transporter
PATSB16_RS20330	COG0842	Transport permease protein
PATSB16_RS20340	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PATSB16_RS20350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PATSB16_RS20360	COG0131	Imidazoleglycerol-phosphate dehydratase
PATSB16_RS20365	COG2095	MarC family integral membrane protein
PATSB16_RS20375	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PATSB16_RS20385	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PATSB16_RS20390	COG0140	phosphoribosyl-ATP diphosphatase activity
PATSB16_RS20405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PATSB16_RS20415	COG0805	protein transport
PATSB16_RS20420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PATSB16_RS20425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PATSB16_RS20430	COG1970	mechanosensitive ion channel activity
PATSB16_RS20435	COG0723	plastoquinol--plastocyanin reductase activity
PATSB16_RS20440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PATSB16_RS20445	COG2857	Cytochrome c1
PATSB16_RS20450	COG0625	glutathione transferase activity
PATSB16_RS20455	COG2969	positive regulation of protein catabolic process
PATSB16_RS20465	COG0625	glutathione transferase activity
PATSB16_RS20485	COG2308	Evidence 4 Homologs of previously reported genes of
PATSB16_RS20505	COG0583	DNA-binding transcription factor activity
PATSB16_RS20510	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PATSB16_RS20515	COG1960	acyl-CoA dehydrogenase activity
PATSB16_RS20540	COG1538	Outer membrane efflux protein
PATSB16_RS20550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PATSB16_RS20560	COG0583	DNA-binding transcription factor activity
PATSB16_RS20565	COG0004	ammonium transporteR
PATSB16_RS20585	COG0163	prenyltransferase activity
PATSB16_RS20590	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PATSB16_RS20595	COG2890	protein-(glutamine-N5) methyltransferase activity
PATSB16_RS20605	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PATSB16_RS20610	COG2261	transglycosylase associated protein
PATSB16_RS20620	COG0488	(ABC) transporter
PATSB16_RS20625	COG0012	GTP binding
PATSB16_RS20630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PATSB16_RS20645	COG0583	DNA-binding transcription factor activity
PATSB16_RS20660	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PATSB16_RS20670	COG0134	indole-3-glycerol-phosphate synthase activity
PATSB16_RS20675	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PATSB16_RS20690	COG0546	phosphoglycolate phosphatase activity
PATSB16_RS20695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PATSB16_RS20700	COG2967	ApaG domain
PATSB16_RS20705	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PATSB16_RS20715	COG2050	protein possibly involved in aromatic compounds catabolism
PATSB16_RS20720	COG1024	Enoyl-CoA hydratase
PATSB16_RS20725	COG0183	Belongs to the thiolase family
PATSB16_RS20735	COG1024	Enoyl-CoA hydratase