locus-tag	class	description
ABW99_RS00010	COG1053	succinate dehydrogenase
ABW99_RS00015	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ABW99_RS00040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABW99_RS00050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABW99_RS00070	COG2866	Carboxypeptidase
ABW99_RS00075	COG3022	response to hydroperoxide
ABW99_RS00085	COG0436	Aminotransferase
ABW99_RS00090	COG0625	glutathione transferase activity
ABW99_RS00095	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABW99_RS00100	COG1024	Enoyl-CoA hydratase
ABW99_RS00110	COG0625	glutathione transferase activity
ABW99_RS00115	COG3422	double-strand break repair
ABW99_RS00140	COG1007	ATP synthesis coupled electron transport
ABW99_RS00155	COG0713	ATP synthesis coupled electron transport
ABW99_RS00165	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABW99_RS00170	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABW99_RS00175	COG1034	ATP synthesis coupled electron transport
ABW99_RS00190	COG0649	NAD binding
ABW99_RS00195	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABW99_RS00200	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABW99_RS00205	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABW99_RS00220	COG0149	triose-phosphate isomerase activity
ABW99_RS00230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABW99_RS00235	COG0251	oxidation-reduction process
ABW99_RS00260	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABW99_RS00265	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS00275	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABW99_RS00280	COG0477	Major facilitator Superfamily
ABW99_RS00295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABW99_RS00305	COG1295	ribonuclease BN
ABW99_RS00320	COG0277	FAD linked oxidase domain protein
ABW99_RS00325	COG0254	rRNA binding
ABW99_RS00335	COG0534	Mate efflux family protein
ABW99_RS00370	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABW99_RS00380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABW99_RS00385	COG2081	HI0933 family
ABW99_RS00390	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABW99_RS00395	COG1469	GTP cyclohydrolase I activity
ABW99_RS00405	COG0142	geranyltranstransferase activity
ABW99_RS00410	COG1722	exodeoxyribonuclease VII activity
ABW99_RS00425	COG1252	NADH dehydrogenase
ABW99_RS00435	COG1611	Belongs to the LOG family
ABW99_RS00445	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ABW99_RS00455	COG0210	DNA helicase
ABW99_RS00460	COG0525	valine-tRNA ligase activity
ABW99_RS00465	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABW99_RS00470	COG0425	Belongs to the sulfur carrier protein TusA family
ABW99_RS00490	COG1942	4-Oxalocrotonate Tautomerase
ABW99_RS00495	COG0235	Class ii aldolase
ABW99_RS00500	COG0477	Major facilitator Superfamily
ABW99_RS00510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS00525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABW99_RS00585	COG4964	Belongs to the GSP D family
ABW99_RS00620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ABW99_RS00630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS00635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS00655	COG1178	ABC-type Fe3 transport system permease component
ABW99_RS00665	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ABW99_RS00700	COG0312	modulator of DNA gyrase
ABW99_RS00705	COG3028	Belongs to the UPF0307 family
ABW99_RS00710	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABW99_RS00730	COG2721	sulfolactate sulfo-lyase activity
ABW99_RS00735	COG2721	sulfolactate sulfo-lyase activity
ABW99_RS00740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABW99_RS00745	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABW99_RS00770	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABW99_RS00775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS00785	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ABW99_RS00790	COG1053	succinate dehydrogenase
ABW99_RS00805	COG0501	Belongs to the peptidase M48B family
ABW99_RS00810	COG1162	GTPase activity
ABW99_RS00815	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ABW99_RS00820	COG0494	nUDIX hydrolase
ABW99_RS00825	COG0335	large ribosomal subunit rRNA binding
ABW99_RS00830	COG0336	Belongs to the RNA methyltransferase TrmD family
ABW99_RS00835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABW99_RS00840	COG0228	four-way junction DNA binding
ABW99_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABW99_RS00870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS00875	COG0686	Belongs to the AlaDH PNT family
ABW99_RS00880	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS00905	COG1024	Enoyl-CoA hydratase
ABW99_RS00915	COG2951	lytic endotransglycosylase activity
ABW99_RS00930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABW99_RS00935	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ABW99_RS00945	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ABW99_RS00955	COG0776	regulation of translation
ABW99_RS00965	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ABW99_RS00970	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABW99_RS00975	COG0287	Prephenate dehydrogenase
ABW99_RS00980	COG0077	Prephenate dehydratase
ABW99_RS00980	COG1605	Chorismate mutase
ABW99_RS00985	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ABW99_RS01005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ABW99_RS01025	COG0697	spore germination
ABW99_RS01050	COG1522	sequence-specific DNA binding
ABW99_RS01060	COG5002	protein histidine kinase activity
ABW99_RS01060	COG5001	Diguanylate cyclase
ABW99_RS01090	COG1132	(ABC) transporter
ABW99_RS01095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABW99_RS01095	COG0189	ligase activity
ABW99_RS01100	COG0189	ligase activity
ABW99_RS01100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABW99_RS01125	COG0248	Ppx GppA phosphatase
ABW99_RS01130	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ABW99_RS01140	COG0745	RESPONSE REGULATOR receiver
ABW99_RS01155	COG0581	inorganic phosphate transmembrane transporter activity
ABW99_RS01160	COG0573	inorganic phosphate transmembrane transporter activity
ABW99_RS01165	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ABW99_RS01170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABW99_RS01175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABW99_RS01180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABW99_RS01190	COG1534	Rna-binding protein
ABW99_RS01200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABW99_RS01205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABW99_RS01215	COG0505	Belongs to the CarA family
ABW99_RS01225	COG1301	dicarboxylic acid transport
ABW99_RS01230	COG4266	Belongs to the allantoicase family
ABW99_RS01255	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS01260	COG1024	Enoyl-CoA hydratase
ABW99_RS01265	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS01280	COG0741	lytic transglycosylase activity
ABW99_RS01280	COG1388	LysM domain
ABW99_RS01285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABW99_RS01295	COG0328	RNA-DNA hybrid ribonuclease activity
ABW99_RS01300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABW99_RS01310	COG1272	protein, Hemolysin III
ABW99_RS01330	COG2814	Major facilitator Superfamily
ABW99_RS01335	COG0010	Belongs to the arginase family
ABW99_RS01340	COG1126	abc transporter atp-binding protein
ABW99_RS01345	COG0765	amino acid transport
ABW99_RS01350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS01360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABW99_RS01385	COG2223	nitrite transmembrane transporter activity
ABW99_RS01390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABW99_RS01400	COG0243	molybdopterin cofactor binding
ABW99_RS01405	COG0583	DNA-binding transcription factor activity
ABW99_RS01410	COG0625	glutathione transferase activity
ABW99_RS01420	COG0587	DNA-directed DNA polymerase activity
ABW99_RS01435	COG2252	PERMEase
ABW99_RS01445	COG3021	interspecies interaction between organisms
ABW99_RS01450	COG2217	Heavy metal translocating P-type atpase
ABW99_RS01460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABW99_RS01460	COG4651	solute:proton antiporter activity
ABW99_RS01490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ABW99_RS01495	COG0402	S-adenosylhomocysteine deaminase activity
ABW99_RS01500	COG2119	membrane
ABW99_RS01510	COG0308	aminopeptidase N
ABW99_RS01520	COG0583	DNA-binding transcription factor activity
ABW99_RS01525	COG0540	Belongs to the ATCase OTCase family
ABW99_RS01540	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
ABW99_RS01545	COG0582	viral genome integration into host DNA
ABW99_RS01550	COG3093	addiction module antidote protein HigA
ABW99_RS01560	COG2860	membrane
ABW99_RS01575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ABW99_RS01585	COG0243	molybdopterin cofactor binding
ABW99_RS01595	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABW99_RS01600	COG0657	acetylesterase activity
ABW99_RS01605	COG0402	S-adenosylhomocysteine deaminase activity
ABW99_RS01610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABW99_RS01625	COG0583	DNA-binding transcription factor activity
ABW99_RS01645	COG0604	alcohol dehydrogenase
ABW99_RS01645	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS01645	COG3321	synthase
ABW99_RS01650	COG0431	NADPH-dependent FMN reductase
ABW99_RS01665	COG2226	methyltransferase
ABW99_RS01680	COG1846	Transcriptional regulator
ABW99_RS01690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABW99_RS01700	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABW99_RS01705	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABW99_RS01710	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS01715	COG3958	Transketolase
ABW99_RS01720	COG3959	Transketolase, thiamine diphosphate binding domain
ABW99_RS01725	COG0583	DNA-binding transcription factor activity
ABW99_RS01730	COG2200	EAL domain
ABW99_RS01735	COG0678	peroxiredoxin activity
ABW99_RS01740	COG2188	Transcriptional regulator
ABW99_RS01745	COG2271	Major facilitator Superfamily
ABW99_RS01785	COG2814	Major facilitator Superfamily
ABW99_RS01800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABW99_RS01810	COG4521	taurine ABC transporter
ABW99_RS01815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABW99_RS01820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS01825	COG2205	protein histidine kinase activity
ABW99_RS01830	COG0745	RESPONSE REGULATOR receiver
ABW99_RS01835	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABW99_RS01845	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABW99_RS01870	COG1414	Transcriptional regulator
ABW99_RS01885	COG1113	amino acid transport
ABW99_RS01895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS01900	COG1414	Transcriptional regulator
ABW99_RS01910	COG0477	Major facilitator Superfamily
ABW99_RS01915	COG1414	Transcriptional regulator
ABW99_RS01935	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS01940	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS01945	COG2271	Major facilitator Superfamily
ABW99_RS01950	COG2084	Dehydrogenase
ABW99_RS01955	COG0824	Thioesterase
ABW99_RS01965	COG0848	biopolymer transport protein
ABW99_RS01975	COG0823	Involved in the tonB-independent uptake of proteins
ABW99_RS01980	COG2885	chlorophyll binding
ABW99_RS01985	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ABW99_RS01995	COG1968	undecaprenyl-diphosphatase activity
ABW99_RS02000	COG2252	PERMEase
ABW99_RS02010	COG3387	PFAM Glycoside hydrolase 15-related
ABW99_RS02015	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABW99_RS02070	COG4789	Type iii secretion
ABW99_RS02100	COG0076	glutamate decarboxylase activity
ABW99_RS02120	COG3033	Beta-eliminating lyase
ABW99_RS02125	COG5001	Diguanylate cyclase
ABW99_RS02125	COG3300	MHYT domain
ABW99_RS02135	COG2909	trisaccharide binding
ABW99_RS02160	COG2814	Major facilitator Superfamily
ABW99_RS02165	COG1522	sequence-specific DNA binding
ABW99_RS02170	COG2423	ornithine cyclodeaminase activity
ABW99_RS02195	COG1999	signal sequence binding
ABW99_RS02230	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABW99_RS02235	COG0438	transferase activity, transferring glycosyl groups
ABW99_RS02255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABW99_RS02280	COG0438	transferase activity, transferring glycosyl groups
ABW99_RS02295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABW99_RS02305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABW99_RS02310	COG2153	protein acetylation
ABW99_RS02315	COG0662	Cupin 2, conserved barrel domain protein
ABW99_RS02315	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ABW99_RS02320	COG2814	Major facilitator Superfamily
ABW99_RS02350	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ABW99_RS02355	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ABW99_RS02365	COG1473	amidohydrolase
ABW99_RS02370	COG0583	DNA-binding transcription factor activity
ABW99_RS02415	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS02425	COG0028	Belongs to the TPP enzyme family
ABW99_RS02430	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS02435	COG1414	Transcriptional regulator
ABW99_RS02450	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS02455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS02465	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS02470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABW99_RS02480	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ABW99_RS02510	COG0322	excinuclease ABC activity
ABW99_RS02520	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABW99_RS02525	COG2204	response regulator
ABW99_RS02535	COG0736	holo-[acyl-carrier-protein] synthase activity
ABW99_RS02540	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ABW99_RS02550	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABW99_RS02555	COG0571	ribonuclease III activity
ABW99_RS02560	COG0681	Belongs to the peptidase S26 family
ABW99_RS02575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABW99_RS02600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABW99_RS02605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABW99_RS02610	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS02620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABW99_RS02625	COG0416	fatty acid biosynthetic process
ABW99_RS02630	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ABW99_RS02635	COG1399	metal-binding, possibly nucleic acid-binding protein
ABW99_RS02640	COG0424	maF-like protein
ABW99_RS02650	COG0616	signal peptide processing
ABW99_RS02650	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ABW99_RS02660	COG0546	phosphoglycolate phosphatase activity
ABW99_RS02665	COG0564	pseudouridine synthase activity
ABW99_RS02670	COG1530	ribonuclease E activity
ABW99_RS02675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABW99_RS02680	COG0746	molybdenum cofactor guanylyltransferase activity
ABW99_RS02685	COG0303	'Molybdopterin
ABW99_RS02695	COG0456	acetyltransferase
ABW99_RS02700	COG1322	Protein conserved in bacteria
ABW99_RS02735	COG0579	oxidoreductase
ABW99_RS02745	COG3384	dioxygenase
ABW99_RS02755	COG1280	lysine exporter protein (LysE YggA)
ABW99_RS02765	COG1278	Cold shock
ABW99_RS02775	COG2943	transferase activity, transferring hexosyl groups
ABW99_RS02775	COG3416	Protein conserved in bacteria
ABW99_RS02780	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ABW99_RS02790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ABW99_RS02795	COG0251	oxidation-reduction process
ABW99_RS02820	COG0235	Class ii aldolase
ABW99_RS02825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ABW99_RS02835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABW99_RS02840	COG1126	abc transporter atp-binding protein
ABW99_RS02845	COG0765	amino acid transport
ABW99_RS02850	COG0765	amino acid transport
ABW99_RS02880	COG0411	ABC transporter
ABW99_RS02910	COG0583	DNA-binding transcription factor activity
ABW99_RS02915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS02920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS02925	COG0765	amino acid transport
ABW99_RS02930	COG1126	abc transporter atp-binding protein
ABW99_RS02955	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABW99_RS02965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ABW99_RS02970	COG0425	Belongs to the sulfur carrier protein TusA family
ABW99_RS02970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABW99_RS02985	COG0859	PFAM glycosyl transferase family 9
ABW99_RS03000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABW99_RS03010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABW99_RS03070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABW99_RS03090	COG0540	Belongs to the ATCase OTCase family
ABW99_RS03095	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABW99_RS03100	COG1678	Uncharacterized ACR, COG1678
ABW99_RS03110	COG1773	rubredoxin
ABW99_RS03115	COG0351	phosphomethylpyrimidine kinase
ABW99_RS03120	COG3307	-O-antigen
ABW99_RS03125	COG4969	Belongs to the N-Me-Phe pilin family
ABW99_RS03130	COG0861	Integral membrane protein TerC family
ABW99_RS03135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ABW99_RS03140	COG0045	succinate-CoA ligase (ADP-forming) activity
ABW99_RS03150	COG2137	regulation of response to DNA damage stimulus
ABW99_RS03155	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABW99_RS03170	COG0477	Major facilitator Superfamily
ABW99_RS03215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABW99_RS03225	COG1396	sequence-specific DNA binding
ABW99_RS03235	COG2271	Major facilitator Superfamily
ABW99_RS03240	COG1902	pentaerythritol trinitrate reductase activity
ABW99_RS03245	COG0668	transmembrane transport
ABW99_RS03275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABW99_RS03300	COG2719	SpoVR family
ABW99_RS03305	COG2718	Belongs to the UPF0229 family
ABW99_RS03310	COG2766	serine protein kinase
ABW99_RS03315	COG0803	Belongs to the bacterial solute-binding protein 9 family
ABW99_RS03320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABW99_RS03325	COG1702	phosphate starvation-inducible protein PhoH
ABW99_RS03330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ABW99_RS03335	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ABW99_RS03345	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ABW99_RS03350	COG0752	glycyl-tRNA synthetase alpha subunit
ABW99_RS03355	COG0751	glycine-tRNA ligase activity
ABW99_RS03360	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ABW99_RS03365	COG0204	Acyl-transferase
ABW99_RS03375	COG0346	lactoylglutathione lyase activity
ABW99_RS03390	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABW99_RS03395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABW99_RS03400	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ABW99_RS03410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ABW99_RS03415	COG0006	proline dipeptidase activity
ABW99_RS03420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABW99_RS03430	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ABW99_RS03435	COG0138	bifunctional purine biosynthesis protein purh
ABW99_RS03440	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABW99_RS03460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ABW99_RS03465	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABW99_RS03470	COG0735	belongs to the Fur family
ABW99_RS03475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABW99_RS03480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABW99_RS03485	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ABW99_RS03495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABW99_RS03515	COG0280	phosphate acetyltransferase
ABW99_RS03515	COG0281	malic enzyme
ABW99_RS03525	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABW99_RS03530	COG1546	Belongs to the CinA family
ABW99_RS03530	COG1058	Belongs to the CinA family
ABW99_RS03535	COG0284	orotidine-5'-phosphate decarboxylase activity
ABW99_RS03540	COG0668	transmembrane transport
ABW99_RS03545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABW99_RS03550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABW99_RS03560	COG0557	exoribonuclease II activity
ABW99_RS03570	COG1881	PFAM PEBP family protein
ABW99_RS03575	COG1490	D-aminoacyl-tRNA deacylase activity
ABW99_RS03590	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ABW99_RS03600	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABW99_RS03605	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABW99_RS03625	COG0418	dihydroorotase activity
ABW99_RS03630	COG0121	glutamine amidotransferase
ABW99_RS03635	COG1126	abc transporter atp-binding protein
ABW99_RS03640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABW99_RS03645	COG0583	DNA-binding transcription factor activity
ABW99_RS03650	COG5265	(ABC) transporter
ABW99_RS03665	COG0183	Belongs to the thiolase family
ABW99_RS03670	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABW99_RS03670	COG1024	Enoyl-CoA hydratase
ABW99_RS03675	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS03685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABW99_RS03690	COG0494	nUDIX hydrolase
ABW99_RS03715	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABW99_RS03730	COG2226	methyltransferase
ABW99_RS03745	COG0025	NhaP-type Na H and K H
ABW99_RS03765	COG1238	metal cluster binding
ABW99_RS03785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABW99_RS03805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABW99_RS03815	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS03820	COG3284	Transcriptional regulator
ABW99_RS03825	COG0596	Alpha beta hydrolase
ABW99_RS03830	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ABW99_RS03835	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
ABW99_RS03845	COG0535	radical SAM domain protein
ABW99_RS03870	COG1846	Transcriptional regulator
ABW99_RS03885	COG2902	Dehydrogenase
ABW99_RS03905	COG0656	L-ascorbic acid biosynthetic process
ABW99_RS03930	COG3344	reverse transcriptase
ABW99_RS03950	COG2233	PERMEase
ABW99_RS03980	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS03985	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABW99_RS04000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS04005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS04010	COG1609	Transcriptional regulator
ABW99_RS04015	COG0629	single-stranded DNA binding
ABW99_RS04020	COG2814	Major facilitator Superfamily
ABW99_RS04040	COG1283	sodium-dependent phosphate transmembrane transporter activity
ABW99_RS04045	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS04080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABW99_RS04105	COG0583	DNA-binding transcription factor activity
ABW99_RS04115	COG1280	lysine exporter protein (LysE YggA)
ABW99_RS04120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABW99_RS04150	COG1137	ATPase activity
ABW99_RS04155	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ABW99_RS04160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ABW99_RS04170	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ABW99_RS04180	COG1660	Displays ATPase and GTPase activities
ABW99_RS04185	COG1194	a g-specific adenine glycosylase
ABW99_RS04190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ABW99_RS04200	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ABW99_RS04215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABW99_RS04225	COG0193	aminoacyl-tRNA hydrolase activity
ABW99_RS04230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABW99_RS04235	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABW99_RS04240	COG0742	ribosomal rna small subunit methyltransferase
ABW99_RS04245	COG1131	(ABC) transporter
ABW99_RS04255	COG0612	Peptidase, M16
ABW99_RS04260	COG0612	Peptidase, M16
ABW99_RS04270	COG0625	glutathione transferase activity
ABW99_RS04280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABW99_RS04290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABW99_RS04310	COG1294	oxidase, subunit
ABW99_RS04315	COG0109	protoheme IX farnesyltransferase activity
ABW99_RS04320	COG1612	heme a metabolic process
ABW99_RS04350	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ABW99_RS04355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABW99_RS04370	COG2226	methyltransferase
ABW99_RS04390	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ABW99_RS04395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ABW99_RS04400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABW99_RS04410	COG0793	Belongs to the peptidase S41A family
ABW99_RS04420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABW99_RS04425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABW99_RS04435	COG0189	ligase activity
ABW99_RS04450	COG0004	ammonium transporteR
ABW99_RS04455	COG0347	Belongs to the P(II) protein family
ABW99_RS04465	COG2960	long-chain fatty acid transporting porin activity
ABW99_RS04480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABW99_RS04490	COG0859	PFAM glycosyl transferase family 9
ABW99_RS04500	COG0321	lipoyl(octanoyl) transferase activity
ABW99_RS04510	COG0583	DNA-binding transcription factor activity
ABW99_RS04515	COG2921	Belongs to the UPF0250 family
ABW99_RS04520	COG1686	Belongs to the peptidase S11 family
ABW99_RS04545	COG1127	ABC transporter
ABW99_RS04550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABW99_RS04555	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ABW99_RS04555	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ABW99_RS04575	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABW99_RS04600	COG1024	Enoyl-CoA hydratase
ABW99_RS04645	COG1410	methionine synthase
ABW99_RS04645	COG0646	methionine synthase
ABW99_RS04675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABW99_RS04680	COG0300	oxidoreductase activity
ABW99_RS04695	COG0789	Transcriptional regulator
ABW99_RS04705	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS04710	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ABW99_RS04715	COG0288	reversible hydration of carbon dioxide
ABW99_RS04720	COG0183	Belongs to the thiolase family
ABW99_RS04725	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS04735	COG3012	SEC-C Motif Domain Protein
ABW99_RS04740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABW99_RS04745	COG1024	Enoyl-CoA hydratase
ABW99_RS04755	COG0156	8-amino-7-oxononanoate synthase activity
ABW99_RS04765	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABW99_RS04790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABW99_RS04825	COG3706	GGDEF domain
ABW99_RS04835	COG0596	Alpha beta hydrolase
ABW99_RS04870	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ABW99_RS04875	COG1733	regulation of RNA biosynthetic process
ABW99_RS04885	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABW99_RS04890	COG1703	isobutyryl-CoA mutase activity
ABW99_RS04890	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ABW99_RS04890	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ABW99_RS04905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS04910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS04930	COG1024	Enoyl-CoA hydratase
ABW99_RS04940	COG1309	transcriptional regulator
ABW99_RS04970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABW99_RS04975	COG1131	(ABC) transporter
ABW99_RS04980	COG0842	Transport permease protein
ABW99_RS04990	COG1739	Uncharacterized protein family UPF0029
ABW99_RS04995	COG0322	excinuclease ABC activity
ABW99_RS05010	COG1562	ergosterol biosynthetic process
ABW99_RS05015	COG1741	Belongs to the pirin family
ABW99_RS05025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABW99_RS05030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS05035	COG0583	DNA-binding transcription factor activity
ABW99_RS05050	COG0586	Pfam SNARE associated Golgi protein
ABW99_RS05070	COG1802	Transcriptional regulator
ABW99_RS05075	COG1024	Enoyl-CoA hydratase
ABW99_RS05080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS05090	COG0247	lactate metabolic process
ABW99_RS05090	COG0277	FAD linked oxidase domain protein
ABW99_RS05100	COG2271	Major facilitator Superfamily
ABW99_RS05105	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABW99_RS05110	COG1802	Transcriptional regulator
ABW99_RS05115	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ABW99_RS05120	COG1234	tRNA 3'-trailer cleavage
ABW99_RS05130	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS05135	COG3473	Maleate cis-trans isomerase
ABW99_RS05155	COG1021	2,3-dihydroxybenzoate-AMP ligase
ABW99_RS05185	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS05190	COG0625	glutathione transferase activity
ABW99_RS05215	COG2814	Major facilitator Superfamily
ABW99_RS05220	COG1846	Transcriptional regulator
ABW99_RS05255	COG0300	oxidoreductase activity
ABW99_RS05270	COG3311	Transcriptional regulator
ABW99_RS05300	COG1280	lysine exporter protein (LysE YggA)
ABW99_RS05310	COG4521	taurine ABC transporter
ABW99_RS05350	COG1522	sequence-specific DNA binding
ABW99_RS05355	COG1280	lysine exporter protein (LysE YggA)
ABW99_RS05365	COG1917	Cupin 2, conserved barrel domain protein
ABW99_RS05365	COG2207	Transcriptional regulator
ABW99_RS05405	COG0410	ABC transporter
ABW99_RS05410	COG0154	amidase activity
ABW99_RS05420	COG1396	sequence-specific DNA binding
ABW99_RS05435	COG2337	Toxic component of a toxin-antitoxin (TA) module
ABW99_RS05445	COG0697	spore germination
ABW99_RS05465	COG0477	Major facilitator Superfamily
ABW99_RS05480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABW99_RS05485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ABW99_RS05495	COG0583	DNA-binding transcription factor activity
ABW99_RS05510	COG0415	Belongs to the DNA photolyase family
ABW99_RS05515	COG0415	Belongs to the DNA photolyase family
ABW99_RS05520	COG3046	protein related to deoxyribodipyrimidine photolyase
ABW99_RS05550	COG0596	Alpha beta hydrolase
ABW99_RS05560	COG1024	Enoyl-CoA hydratase
ABW99_RS05570	COG1414	Transcriptional regulator
ABW99_RS05580	COG0765	amino acid transport
ABW99_RS05585	COG0765	amino acid transport
ABW99_RS05595	COG1126	abc transporter atp-binding protein
ABW99_RS05605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS05610	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABW99_RS05620	COG0642	Histidine kinase
ABW99_RS05625	COG1902	pentaerythritol trinitrate reductase activity
ABW99_RS05625	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABW99_RS05645	COG0517	IMP dehydrogenase activity
ABW99_RS05675	COG0583	DNA-binding transcription factor activity
ABW99_RS05695	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS05700	COG0625	glutathione transferase activity
ABW99_RS05705	COG0625	glutathione transferase activity
ABW99_RS05725	COG5611	PilT protein domain protein
ABW99_RS05730	COG2271	Major facilitator Superfamily
ABW99_RS05745	COG0583	DNA-binding transcription factor activity
ABW99_RS05750	COG2862	Uncharacterized protein family, UPF0114
ABW99_RS05755	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABW99_RS05760	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABW99_RS05770	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ABW99_RS05775	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS05795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABW99_RS05800	COG3246	L-lysine catabolic process to acetate
ABW99_RS05810	COG0617	tRNA 3'-terminal CCA addition
ABW99_RS05825	COG0741	lytic transglycosylase activity
ABW99_RS05830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ABW99_RS05840	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ABW99_RS05845	COG1984	allophanate hydrolase subunit 2
ABW99_RS05850	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ABW99_RS05860	COG0583	DNA-binding transcription factor activity
ABW99_RS05865	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ABW99_RS05875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABW99_RS05880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABW99_RS05900	COG0411	ABC transporter
ABW99_RS05905	COG0410	ABC transporter
ABW99_RS05915	COG0831	urea catabolic process
ABW99_RS05920	COG0832	Belongs to the urease beta subunit family
ABW99_RS05935	COG0830	nickel cation binding
ABW99_RS05940	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ABW99_RS05950	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ABW99_RS05955	COG1950	PFAM Membrane protein of
ABW99_RS05960	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ABW99_RS05965	COG0708	Exodeoxyribonuclease III
ABW99_RS05970	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS05975	COG0667	Aldo Keto reductase
ABW99_RS05980	COG0583	DNA-binding transcription factor activity
ABW99_RS05985	COG2329	Antibiotic biosynthesis monooxygenase
ABW99_RS06000	COG0400	carboxylic ester hydrolase activity
ABW99_RS06005	COG2814	Major facilitator Superfamily
ABW99_RS06010	COG2813	Specifically methylates the guanine in position
ABW99_RS06010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABW99_RS06015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABW99_RS06020	COG1309	transcriptional regulator
ABW99_RS06035	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABW99_RS06040	COG1595	DNA-templated transcription, initiation
ABW99_RS06065	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ABW99_RS06075	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ABW99_RS06080	COG3344	reverse transcriptase
ABW99_RS06090	COG0523	cobalamin synthesis protein
ABW99_RS06100	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ABW99_RS06105	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ABW99_RS06115	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABW99_RS06120	COG1560	Kdo2-lipid A biosynthetic process
ABW99_RS06125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABW99_RS06135	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS06155	COG0154	amidase activity
ABW99_RS06160	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABW99_RS06165	COG1077	Cell shape determining protein MreB Mrl
ABW99_RS06170	COG1792	Involved in formation and maintenance of cell shape
ABW99_RS06180	COG0768	penicillin binding
ABW99_RS06185	COG0772	Belongs to the SEDS family
ABW99_RS06195	COG0720	synthase
ABW99_RS06200	COG0602	queuosine metabolic process
ABW99_RS06205	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABW99_RS06215	COG2204	response regulator
ABW99_RS06215	COG2204	response regulator
ABW99_RS06220	COG5000	phosphorelay sensor kinase activity
ABW99_RS06235	COG0501	Belongs to the peptidase M48B family
ABW99_RS06240	COG1280	lysine exporter protein (LysE YggA)
ABW99_RS06245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABW99_RS06250	COG0242	peptide deformylase activity
ABW99_RS06255	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABW99_RS06255	COG0758	DNA mediated transformation
ABW99_RS06280	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ABW99_RS06285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABW99_RS06315	COG5001	Diguanylate cyclase
ABW99_RS06315	COG1716	ATPase activity
ABW99_RS06320	COG2223	nitrite transmembrane transporter activity
ABW99_RS06350	COG2814	Major facilitator Superfamily
ABW99_RS06360	COG0531	amino acid
ABW99_RS06375	COG0842	Transport permease protein
ABW99_RS06380	COG1131	(ABC) transporter
ABW99_RS06390	COG0583	DNA-binding transcription factor activity
ABW99_RS06395	COG0583	DNA-binding transcription factor activity
ABW99_RS06400	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS06405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS06410	COG0477	Major facilitator Superfamily
ABW99_RS06415	COG1522	sequence-specific DNA binding
ABW99_RS06425	COG0626	cystathionine gamma-synthase activity
ABW99_RS06430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS06435	COG0765	amino acid transport
ABW99_RS06440	COG1126	abc transporter atp-binding protein
ABW99_RS06465	COG0583	DNA-binding transcription factor activity
ABW99_RS06490	COG0405	Gamma-glutamyltransferase
ABW99_RS06495	COG1177	transmembrane transport
ABW99_RS06500	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABW99_RS06505	COG3842	ATPase activity
ABW99_RS06515	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ABW99_RS06520	COG2186	Transcriptional regulator
ABW99_RS06540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABW99_RS06545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABW99_RS06565	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABW99_RS06570	COG2733	membrane
ABW99_RS06585	COG2199	diguanylate cyclase activity
ABW99_RS06585	COG2200	EAL domain
ABW99_RS06585	COG3287	FIST C domain
ABW99_RS06610	COG1201	RNA secondary structure unwinding
ABW99_RS06625	COG0514	ATP-dependent DNA helicase (RecQ)
ABW99_RS06630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ABW99_RS06645	COG4372	Transposase
ABW99_RS06670	COG0720	synthase
ABW99_RS06710	COG3550	peptidyl-serine autophosphorylation
ABW99_RS06735	COG0592	DNA-directed DNA polymerase activity
ABW99_RS06740	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABW99_RS06745	COG0594	ribonuclease P activity
ABW99_RS06755	COG0706	membrane insertase activity
ABW99_RS06760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABW99_RS06765	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ABW99_RS06775	COG2814	Major facilitator Superfamily
ABW99_RS06785	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ABW99_RS06785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS06820	COG2154	pterin-4-alpha-carbinolamine dehydratase
ABW99_RS06835	COG2423	ornithine cyclodeaminase activity
ABW99_RS06840	COG0583	DNA-binding transcription factor activity
ABW99_RS06850	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS06855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABW99_RS06870	COG1473	amidohydrolase
ABW99_RS06875	COG1802	Transcriptional regulator
ABW99_RS06880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS06895	COG0367	asparagine synthase
ABW99_RS06900	COG1522	sequence-specific DNA binding
ABW99_RS06910	COG0114	fumarate hydratase activity
ABW99_RS06915	COG0583	DNA-binding transcription factor activity
ABW99_RS06945	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABW99_RS06950	COG1172	Belongs to the binding-protein-dependent transport system permease family
ABW99_RS06960	COG1846	Transcriptional regulator
ABW99_RS06980	COG2070	2-Nitropropane dioxygenase
ABW99_RS06985	COG0445	tRNA wobble uridine modification
ABW99_RS07000	COG1192	Involved in chromosome partitioning
ABW99_RS07005	COG1475	DNA binding
ABW99_RS07010	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABW99_RS07020	COG0356	it plays a direct role in the translocation of protons across the membrane
ABW99_RS07030	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABW99_RS07035	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABW99_RS07045	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABW99_RS07050	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABW99_RS07055	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABW99_RS07070	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS07090	COG1360	Flagellar Motor Protein
ABW99_RS07095	COG0745	RESPONSE REGULATOR receiver
ABW99_RS07100	COG2198	Histidine kinase
ABW99_RS07100	COG0643	Histidine kinase
ABW99_RS07105	COG0835	chemotaxis
ABW99_RS07110	COG0840	transmembrane signaling receptor activity
ABW99_RS07110	COG0840	transmembrane signaling receptor activity
ABW99_RS07115	COG0840	transmembrane signaling receptor activity
ABW99_RS07125	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ABW99_RS07130	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ABW99_RS07140	COG0745	RESPONSE REGULATOR receiver
ABW99_RS07145	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ABW99_RS07150	COG0667	Aldo Keto reductase
ABW99_RS07155	COG0583	DNA-binding transcription factor activity
ABW99_RS07165	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABW99_RS07180	COG1191	sigma factor activity
ABW99_RS07205	COG1558	bacterial-type flagellum-dependent cell motility
ABW99_RS07220	COG4787	bacterial-type flagellum-dependent cell motility
ABW99_RS07230	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ABW99_RS07235	COG1706	bacterial-type flagellum-dependent cell motility
ABW99_RS07240	COG1705	Flagellar rod assembly protein muramidase FlgJ
ABW99_RS07240	COG3951	Flagellar rod assembly protein muramidase FlgJ
ABW99_RS07245	COG1256	bacterial-type flagellum assembly
ABW99_RS07265	COG1338	Plays a role in the flagellum-specific transport system
ABW99_RS07270	COG3190	flagellar
ABW99_RS07285	COG1580	Controls the rotational direction of flagella during chemotaxis
ABW99_RS07320	COG1677	Flagellar hook-basal body complex protein FliE
ABW99_RS07325	COG2257	FlhB HrpN YscU SpaS Family
ABW99_RS07345	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ABW99_RS07385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS07405	COG2828	Protein conserved in bacteria
ABW99_RS07420	COG3245	cytochrome
ABW99_RS07425	COG0210	DNA helicase
ABW99_RS07440	COG0509	glycine decarboxylation via glycine cleavage system
ABW99_RS07445	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABW99_RS07445	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABW99_RS07450	COG1760	l-serine dehydratase
ABW99_RS07460	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS07465	COG0028	Belongs to the TPP enzyme family
ABW99_RS07470	COG0583	DNA-binding transcription factor activity
ABW99_RS07475	COG0477	Major facilitator Superfamily
ABW99_RS07485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ABW99_RS07485	COG0506	proline dehydrogenase activity
ABW99_RS07485	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ABW99_RS07490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABW99_RS07505	COG0657	acetylesterase activity
ABW99_RS07510	COG1832	CoA-binding protein
ABW99_RS07515	COG3622	Belongs to the hyi family
ABW99_RS07540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABW99_RS07550	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ABW99_RS07555	COG0792	nuclease activity
ABW99_RS07560	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ABW99_RS07565	COG2823	Periplasmic or secreted lipoprotein
ABW99_RS07580	COG3047	cAMP biosynthetic process
ABW99_RS07610	COG0583	DNA-binding transcription factor activity
ABW99_RS07620	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS07625	COG0443	Heat shock 70 kDa protein
ABW99_RS07630	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ABW99_RS07635	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABW99_RS07650	COG2233	PERMEase
ABW99_RS07655	COG0513	Belongs to the DEAD box helicase family
ABW99_RS07660	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ABW99_RS07675	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABW99_RS07680	COG1763	Mo-molybdopterin cofactor biosynthetic process
ABW99_RS07685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABW99_RS07690	COG2814	Major facilitator Superfamily
ABW99_RS07695	COG0280	phosphate acetyltransferase
ABW99_RS07695	COG0281	malic enzyme
ABW99_RS07715	COG1522	sequence-specific DNA binding
ABW99_RS07740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABW99_RS07745	COG2151	metal-sulfur cluster biosynthetic enzyme
ABW99_RS07750	COG3396	Phenylacetate-CoA oxygenase
ABW99_RS07755	COG3460	Phenylacetate-CoA oxygenase
ABW99_RS07760	COG3396	Phenylacetate-CoA oxygenase
ABW99_RS07815	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABW99_RS07830	COG0081	regulation of translation
ABW99_RS07840	COG0222	ribosome binding
ABW99_RS07845	COG0085	RNA polymerase activity
ABW99_RS07855	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABW99_RS07860	COG0049	tRNA binding
ABW99_RS07875	COG0051	transcription antitermination factor activity, RNA binding
ABW99_RS07880	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABW99_RS07890	COG0089	rRNA binding
ABW99_RS07895	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABW99_RS07905	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ABW99_RS07910	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABW99_RS07915	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABW99_RS07920	COG0255	Belongs to the universal ribosomal protein uL29 family
ABW99_RS07925	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABW99_RS07930	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABW99_RS07935	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABW99_RS07940	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ABW99_RS07955	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABW99_RS07960	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ABW99_RS07965	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABW99_RS07975	COG0200	Binds to the 23S rRNA
ABW99_RS07980	COG0201	protein transport
ABW99_RS07990	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABW99_RS07995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ABW99_RS08000	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABW99_RS08005	COG0202	RNA polymerase activity
ABW99_RS08020	COG4232	protein-disulfide reductase activity
ABW99_RS08030	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABW99_RS08040	COG1333	cytochrome c biogenesis protein
ABW99_RS08045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABW99_RS08050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABW99_RS08055	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ABW99_RS08065	COG1965	Belongs to the frataxin family
ABW99_RS08105	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABW99_RS08110	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ABW99_RS08115	COG4575	ribosome binding
ABW99_RS08120	COG3047	cAMP biosynthetic process
ABW99_RS08125	COG3047	cAMP biosynthetic process
ABW99_RS08135	COG0070	glutamate synthase
ABW99_RS08135	COG0069	glutamate synthase activity
ABW99_RS08135	COG0067	glutamate synthase
ABW99_RS08145	COG4178	(ABC) transporter
ABW99_RS08170	COG1127	ABC transporter
ABW99_RS08175	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABW99_RS08180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ABW99_RS08185	COG2853	Lipoprotein
ABW99_RS08200	COG1131	(ABC) transporter
ABW99_RS08205	COG0842	Transport permease protein
ABW99_RS08215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABW99_RS08225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABW99_RS08235	COG0131	Imidazoleglycerol-phosphate dehydratase
ABW99_RS08240	COG2095	MarC family integral membrane protein
ABW99_RS08250	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABW99_RS08260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABW99_RS08265	COG0140	phosphoribosyl-ATP diphosphatase activity
ABW99_RS08280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABW99_RS08290	COG0805	protein transport
ABW99_RS08295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABW99_RS08300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABW99_RS08305	COG1970	mechanosensitive ion channel activity
ABW99_RS08310	COG0723	plastoquinol--plastocyanin reductase activity
ABW99_RS08315	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ABW99_RS08320	COG2857	Cytochrome c1
ABW99_RS08325	COG0625	glutathione transferase activity
ABW99_RS08330	COG2969	positive regulation of protein catabolic process
ABW99_RS08340	COG0625	glutathione transferase activity
ABW99_RS08360	COG2308	Evidence 4 Homologs of previously reported genes of
ABW99_RS08380	COG0583	DNA-binding transcription factor activity
ABW99_RS08385	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ABW99_RS08390	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS08415	COG1538	Outer membrane efflux protein
ABW99_RS08425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABW99_RS08435	COG0583	DNA-binding transcription factor activity
ABW99_RS08440	COG0004	ammonium transporteR
ABW99_RS08460	COG0163	prenyltransferase activity
ABW99_RS08465	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ABW99_RS08470	COG2890	protein-(glutamine-N5) methyltransferase activity
ABW99_RS08480	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABW99_RS08485	COG2261	transglycosylase associated protein
ABW99_RS08495	COG0488	(ABC) transporter
ABW99_RS08500	COG0012	GTP binding
ABW99_RS08505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABW99_RS08520	COG0583	DNA-binding transcription factor activity
ABW99_RS08535	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABW99_RS08545	COG0134	indole-3-glycerol-phosphate synthase activity
ABW99_RS08550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABW99_RS08565	COG0546	phosphoglycolate phosphatase activity
ABW99_RS08570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABW99_RS08575	COG2967	ApaG domain
ABW99_RS08580	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ABW99_RS08590	COG2050	protein possibly involved in aromatic compounds catabolism
ABW99_RS08595	COG1024	Enoyl-CoA hydratase
ABW99_RS08600	COG0183	Belongs to the thiolase family
ABW99_RS08610	COG1024	Enoyl-CoA hydratase
ABW99_RS08640	COG1473	amidohydrolase
ABW99_RS08645	COG0243	molybdopterin cofactor binding
ABW99_RS08660	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS08665	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ABW99_RS08670	COG2001	Belongs to the MraZ family
ABW99_RS08675	COG0275	rRNA processing
ABW99_RS08680	COG3116	cell division
ABW99_RS08690	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABW99_RS08695	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ABW99_RS08725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABW99_RS08730	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABW99_RS08735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ABW99_RS08745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABW99_RS08760	COG0653	protein targeting
ABW99_RS08775	COG0494	nUDIX hydrolase
ABW99_RS08780	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ABW99_RS08785	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ABW99_RS08810	COG4536	flavin adenine dinucleotide binding
ABW99_RS08820	COG0142	geranyltranstransferase activity
ABW99_RS08825	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABW99_RS08830	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ABW99_RS08835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABW99_RS08860	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ABW99_RS08865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABW99_RS08870	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABW99_RS08885	COG3023	N-Acetylmuramoyl-L-alanine amidase
ABW99_RS08920	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ABW99_RS08935	COG0439	Biotin carboxylase
ABW99_RS08940	COG0511	ligase activity, forming carbon-carbon bonds
ABW99_RS08945	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ABW99_RS08960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABW99_RS08965	COG3150	esterase
ABW99_RS08980	COG0632	four-way junction helicase activity
ABW99_RS08990	COG1981	membrane
ABW99_RS09000	COG0800	Aldolase
ABW99_RS09010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABW99_RS09035	COG0482	sulfurtransferase activity
ABW99_RS09040	COG0069	glutamate synthase activity
ABW99_RS09045	COG0625	glutathione transferase activity
ABW99_RS09055	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ABW99_RS09060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABW99_RS09065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABW99_RS09070	COG1862	Preprotein translocase
ABW99_RS09075	COG0343	queuine tRNA-ribosyltransferase activity
ABW99_RS09080	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABW99_RS09085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ABW99_RS09095	COG0583	DNA-binding transcription factor activity
ABW99_RS09100	COG0783	Belongs to the Dps family
ABW99_RS09105	COG3344	reverse transcriptase
ABW99_RS09125	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ABW99_RS09145	COG0386	Belongs to the glutathione peroxidase family
ABW99_RS09150	COG1346	cytolysis
ABW99_RS09155	COG1380	Effector of murein hydrolase LrgA
ABW99_RS09160	COG0247	lactate metabolic process
ABW99_RS09165	COG0277	FAD linked oxidase domain protein
ABW99_RS09170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABW99_RS09175	COG0277	FAD linked oxidase domain protein
ABW99_RS09180	COG0277	FAD linked oxidase domain protein
ABW99_RS09185	COG2096	Adenosyltransferase
ABW99_RS09190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ABW99_RS09195	COG0312	modulator of DNA gyrase
ABW99_RS09200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABW99_RS09210	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ABW99_RS09215	COG0497	DNA recombination
ABW99_RS09225	COG1420	regulation of RNA biosynthetic process
ABW99_RS09235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABW99_RS09245	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ABW99_RS09250	COG0443	Heat shock 70 kDa protein
ABW99_RS09255	COG0484	heat shock protein binding
ABW99_RS09260	COG0512	Glutamine amidotransferase of anthranilate synthase
ABW99_RS09260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABW99_RS09265	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ABW99_RS09270	COG1428	Deoxynucleoside kinase
ABW99_RS09275	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ABW99_RS09290	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABW99_RS09295	COG0628	permease
ABW99_RS09310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ABW99_RS09315	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ABW99_RS09320	COG0586	Pfam SNARE associated Golgi protein
ABW99_RS09325	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABW99_RS09330	COG0802	atpase or kinase
ABW99_RS09335	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ABW99_RS09340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABW99_RS09345	COG4974	Belongs to the 'phage' integrase family
ABW99_RS09350	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS09360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ABW99_RS09365	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ABW99_RS09380	COG3123	guanosine phosphorylase activity
ABW99_RS09385	COG0137	argininosuccinate synthase activity
ABW99_RS09390	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABW99_RS09400	COG0268	Binds directly to 16S ribosomal RNA
ABW99_RS09405	COG0728	peptidoglycan biosynthetic process
ABW99_RS09410	COG2912	Transglutaminase-like superfamily
ABW99_RS09425	COG0563	adenylate kinase activity
ABW99_RS09430	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ABW99_RS09450	COG0811	peptide transport
ABW99_RS09455	COG1570	exodeoxyribonuclease VII activity
ABW99_RS09460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABW99_RS09485	COG1278	Cold shock
ABW99_RS09490	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ABW99_RS09495	COG0542	response to heat
ABW99_RS09500	COG0756	dUTP diphosphatase activity
ABW99_RS09505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABW99_RS09510	COG2814	Major facilitator Superfamily
ABW99_RS09520	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ABW99_RS09525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABW99_RS09530	COG0196	riboflavin kinase activity
ABW99_RS09535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ABW99_RS09540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABW99_RS09540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ABW99_RS09545	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ABW99_RS09545	COG3264	Mechanosensitive ion channel
ABW99_RS09555	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ABW99_RS09565	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ABW99_RS09575	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ABW99_RS09580	COG2003	Belongs to the UPF0758 family
ABW99_RS09585	COG1047	Peptidyl-prolyl cis-trans
ABW99_RS09590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ABW99_RS09610	COG0411	ABC transporter
ABW99_RS09625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABW99_RS09630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABW99_RS09630	COG0543	2 iron, 2 sulfur cluster binding
ABW99_RS09670	COG3237	CsbD-like
ABW99_RS09675	COG4585	Histidine kinase
ABW99_RS09685	COG2197	response regulator
ABW99_RS09690	COG2201	protein-glutamate methylesterase activity
ABW99_RS09695	COG3300	MHYT domain
ABW99_RS09695	COG5001	Diguanylate cyclase
ABW99_RS09705	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ABW99_RS09710	COG0741	lytic transglycosylase activity
ABW99_RS09715	COG0436	Aminotransferase
ABW99_RS09720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABW99_RS09725	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABW99_RS09735	COG4336	lyase activity
ABW99_RS09740	COG0583	DNA-binding transcription factor activity
ABW99_RS09750	COG0583	DNA-binding transcription factor activity
ABW99_RS09795	COG1686	Belongs to the peptidase S11 family
ABW99_RS09805	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABW99_RS09805	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABW99_RS09820	COG1704	LemA family
ABW99_RS09825	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABW99_RS09830	COG0671	phosphoesterase, PA-phosphatase related
ABW99_RS09835	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ABW99_RS09845	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ABW99_RS09855	COG0837	glucose binding
ABW99_RS09855	COG1737	Transcriptional regulator
ABW99_RS09860	COG3360	Dodecin
ABW99_RS09865	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABW99_RS09875	COG2181	nitrate reductase activity
ABW99_RS09880	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ABW99_RS09885	COG1140	nitrate reductase beta subunit
ABW99_RS09890	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ABW99_RS09900	COG1017	nitric oxide dioxygenase activity
ABW99_RS09900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABW99_RS09925	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABW99_RS09930	COG1116	anion transmembrane transporter activity
ABW99_RS09935	COG0640	Transcriptional regulator
ABW99_RS09955	COG0477	Major facilitator Superfamily
ABW99_RS09960	COG0477	Major facilitator Superfamily
ABW99_RS09965	COG0531	amino acid
ABW99_RS09975	COG0583	DNA-binding transcription factor activity
ABW99_RS09990	COG4977	sequence-specific DNA binding
ABW99_RS09995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS10000	COG0765	amino acid transport
ABW99_RS10005	COG1126	abc transporter atp-binding protein
ABW99_RS10010	COG0252	asparaginase activity
ABW99_RS10035	COG0457	Tetratricopeptide repeat
ABW99_RS10045	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS10050	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS10085	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ABW99_RS10095	COG0315	cyclic pyranopterin monophosphate synthase activity
ABW99_RS10105	COG0429	hydrolase of the alpha beta-hydrolase fold
ABW99_RS10140	COG0126	phosphoglycerate kinase activity
ABW99_RS10145	COG0469	pyruvate kinase activity
ABW99_RS10155	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABW99_RS10160	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABW99_RS10165	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ABW99_RS10170	COG0009	L-threonylcarbamoyladenylate synthase
ABW99_RS10185	COG2027	D-alanyl-D-alanine carboxypeptidase
ABW99_RS10195	COG0642	Histidine kinase
ABW99_RS10200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABW99_RS10210	COG3608	succinylglutamate desuccinylase aspartoacylase
ABW99_RS10210	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ABW99_RS10250	COG1309	transcriptional regulator
ABW99_RS10255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABW99_RS10260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABW99_RS10295	COG4970	Tfp pilus assembly protein FimT
ABW99_RS10320	COG4575	ribosome binding
ABW99_RS10325	COG0450	alkyl hydroperoxide reductase
ABW99_RS10330	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS10340	COG3483	tryptophan 2,3-dioxygenase activity
ABW99_RS10350	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ABW99_RS10355	COG1522	sequence-specific DNA binding
ABW99_RS10365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABW99_RS10370	COG2309	aminopeptidase activity
ABW99_RS10375	COG0596	Alpha beta hydrolase
ABW99_RS10390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABW99_RS10400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ABW99_RS10405	COG0259	pyridoxamine-phosphate oxidase activity
ABW99_RS10410	COG2982	Protein involved in outer membrane biogenesis
ABW99_RS10415	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ABW99_RS10420	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS10435	COG0028	Belongs to the TPP enzyme family
ABW99_RS10510	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS10520	COG0778	Nitroreductase
ABW99_RS10535	COG2409	Drug exporters of the RND superfamily
ABW99_RS10550	COG2207	Transcriptional regulator
ABW99_RS10565	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABW99_RS10570	COG1845	cytochrome c oxidase, subunit III
ABW99_RS10575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABW99_RS10580	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ABW99_RS10585	COG0477	Major facilitator Superfamily
ABW99_RS10590	COG3002	Belongs to the UPF0753 family
ABW99_RS10595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABW99_RS10600	COG0583	DNA-binding transcription factor activity
ABW99_RS10615	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABW99_RS10625	COG0842	Transport permease protein
ABW99_RS10630	COG0842	Transport permease protein
ABW99_RS10630	COG1129	ABC transporter
ABW99_RS10635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABW99_RS10650	COG1560	Kdo2-lipid A biosynthetic process
ABW99_RS10685	COG4633	Protein conserved in bacteria
ABW99_RS10745	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABW99_RS10760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABW99_RS10770	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABW99_RS10885	COG4372	Transposase
ABW99_RS10895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABW99_RS10935	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABW99_RS10950	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABW99_RS10965	COG0420	3'-5' exonuclease activity
ABW99_RS11025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABW99_RS11045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ABW99_RS11060	COG3328	transposase activity
ABW99_RS11120	COG2159	amidohydrolase
ABW99_RS11175	COG1139	Iron-sulfur cluster binding protein
ABW99_RS11185	COG0247	lactate metabolic process
ABW99_RS11190	COG2186	Transcriptional regulator
ABW99_RS11195	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ABW99_RS11205	COG0302	gtp cyclohydrolase
ABW99_RS11225	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ABW99_RS11230	COG5001	Diguanylate cyclase
ABW99_RS11235	COG1024	Enoyl-CoA hydratase
ABW99_RS11240	COG5001	Diguanylate cyclase
ABW99_RS11240	COG3300	MHYT domain
ABW99_RS11265	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABW99_RS11305	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ABW99_RS11310	COG1802	Transcriptional regulator
ABW99_RS11315	COG2814	Major facilitator Superfamily
ABW99_RS11330	COG1113	amino acid transport
ABW99_RS11340	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS11345	COG0436	Aminotransferase
ABW99_RS11375	COG2916	Histone family protein nucleoid-structuring protein H-NS
ABW99_RS11390	COG2197	response regulator
ABW99_RS11400	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ABW99_RS11405	COG1074	ATP-dependent DNA helicase activity
ABW99_RS11410	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABW99_RS11420	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABW99_RS11425	COG1278	Cold shock
ABW99_RS11435	COG1253	flavin adenine dinucleotide binding
ABW99_RS11440	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ABW99_RS11450	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABW99_RS11455	COG0840	transmembrane signaling receptor activity
ABW99_RS11470	COG0513	Belongs to the DEAD box helicase family
ABW99_RS11475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABW99_RS11480	COG1054	Belongs to the UPF0176 family
ABW99_RS11495	COG1216	Glycosyl transferase, family 2
ABW99_RS11495	COG0463	Glycosyl transferase, family 2
ABW99_RS11520	COG1530	ribonuclease E activity
ABW99_RS11525	COG0424	maF-like protein
ABW99_RS11530	COG0584	glycerophosphoryl diester phosphodiesterase
ABW99_RS11540	COG0395	ABC-type sugar transport system, permease component
ABW99_RS11545	COG1175	transmembrane transport
ABW99_RS11550	COG1653	transport
ABW99_RS11555	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABW99_RS11560	COG0799	negative regulation of ribosome biogenesis
ABW99_RS11565	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ABW99_RS11570	COG0408	coproporphyrinogen oxidase activity
ABW99_RS11590	COG0151	Belongs to the GarS family
ABW99_RS11595	COG0217	transcriptional regulatory protein
ABW99_RS11600	COG1620	l-lactate permease
ABW99_RS11605	COG0697	spore germination
ABW99_RS11630	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ABW99_RS11635	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS11645	COG0583	DNA-binding transcription factor activity
ABW99_RS11650	COG3284	Transcriptional regulator
ABW99_RS11655	COG0583	DNA-binding transcription factor activity
ABW99_RS11660	COG3328	transposase activity
ABW99_RS11665	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS11675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABW99_RS11680	COG0183	Belongs to the thiolase family
ABW99_RS11685	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS11700	COG0436	Aminotransferase
ABW99_RS11725	COG2721	sulfolactate sulfo-lyase activity
ABW99_RS11735	COG0667	Aldo Keto reductase
ABW99_RS11750	COG4608	Belongs to the ABC transporter superfamily
ABW99_RS11755	COG0444	Belongs to the ABC transporter superfamily
ABW99_RS11760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABW99_RS11765	COG0747	negative chemotaxis
ABW99_RS11770	COG1473	amidohydrolase
ABW99_RS11775	COG0601	transmembrane transport
ABW99_RS11825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABW99_RS11825	COG2169	Transcriptional regulator
ABW99_RS11840	COG2814	Major facilitator Superfamily
ABW99_RS11845	COG2860	membrane
ABW99_RS11865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABW99_RS11870	COG0456	acetyltransferase
ABW99_RS11875	COG1846	Transcriptional regulator
ABW99_RS11875	COG0456	acetyltransferase
ABW99_RS11895	COG0667	Aldo Keto reductase
ABW99_RS11910	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABW99_RS11915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS11920	COG1280	lysine exporter protein (LysE YggA)
ABW99_RS11925	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS11925	COG3321	synthase
ABW99_RS11925	COG0604	alcohol dehydrogenase
ABW99_RS11930	COG0583	DNA-binding transcription factor activity
ABW99_RS11965	COG0789	Transcriptional regulator
ABW99_RS11985	COG2814	Major facilitator Superfamily
ABW99_RS11985	COG0477	Major facilitator Superfamily
ABW99_RS11990	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ABW99_RS12010	COG0583	DNA-binding transcription factor activity
ABW99_RS12015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABW99_RS12035	COG0640	Transcriptional regulator
ABW99_RS12050	COG1959	2 iron, 2 sulfur cluster binding
ABW99_RS12060	COG2151	metal-sulfur cluster biosynthetic enzyme
ABW99_RS12080	COG1686	Belongs to the peptidase S11 family
ABW99_RS12090	COG2084	Dehydrogenase
ABW99_RS12110	COG0583	DNA-binding transcription factor activity
ABW99_RS12115	COG0730	response to heat
ABW99_RS12120	COG0175	sulfate reduction
ABW99_RS12130	COG2895	sulfate adenylyltransferase (ATP) activity
ABW99_RS12135	COG1648	precorrin-2 dehydrogenase activity
ABW99_RS12135	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABW99_RS12150	COG0795	lipopolysaccharide-transporting ATPase activity
ABW99_RS12155	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABW99_RS12175	COG0583	DNA-binding transcription factor activity
ABW99_RS12180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ABW99_RS12185	COG1802	Transcriptional regulator
ABW99_RS12210	COG0410	ABC transporter
ABW99_RS12225	COG1228	amidohydrolase
ABW99_RS12230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABW99_RS12245	COG1024	Enoyl-CoA hydratase
ABW99_RS12250	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS12285	COG4206	TonB-dependent receptor
ABW99_RS12290	COG4139	cobalamin transport
ABW99_RS12295	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ABW99_RS12300	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ABW99_RS12305	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ABW99_RS12315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABW99_RS12330	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABW99_RS12335	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABW99_RS12340	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ABW99_RS12350	COG0729	surface antigen
ABW99_RS12365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABW99_RS12365	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABW99_RS12370	COG3047	cAMP biosynthetic process
ABW99_RS12370	COG2885	chlorophyll binding
ABW99_RS12375	COG0489	protein tyrosine kinase activity
ABW99_RS12380	COG0717	Belongs to the dCTP deaminase family
ABW99_RS12410	COG1595	DNA-templated transcription, initiation
ABW99_RS12420	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ABW99_RS12425	COG0181	hydroxymethylbilane synthase activity
ABW99_RS12445	COG2271	Major facilitator Superfamily
ABW99_RS12460	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ABW99_RS12465	COG0247	lactate metabolic process
ABW99_RS12470	COG0277	FAD linked oxidase domain protein
ABW99_RS12475	COG0277	FAD linked oxidase domain protein
ABW99_RS12495	COG0347	Belongs to the P(II) protein family
ABW99_RS12500	COG2840	Smr protein MutS2
ABW99_RS12505	COG0492	ferredoxin-NADP+ reductase activity
ABW99_RS12510	COG1674	ftsk spoiiie
ABW99_RS12515	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ABW99_RS12520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABW99_RS12525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABW99_RS12535	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABW99_RS12550	COG0642	Histidine kinase
ABW99_RS12585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS12605	COG1850	ribulose-bisphosphate carboxylase activity
ABW99_RS12615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABW99_RS12625	COG1609	Transcriptional regulator
ABW99_RS12635	COG3842	ATPase activity
ABW99_RS12655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ABW99_RS12660	COG0583	DNA-binding transcription factor activity
ABW99_RS12665	COG1929	Belongs to the glycerate kinase type-1 family
ABW99_RS12675	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ABW99_RS12685	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS12700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS12705	COG3938	Belongs to the proline racemase family
ABW99_RS12710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABW99_RS12725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABW99_RS12730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABW99_RS12740	COG1561	YicC-like family, N-terminal region
ABW99_RS12755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABW99_RS12765	COG1741	Belongs to the pirin family
ABW99_RS12785	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ABW99_RS12790	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ABW99_RS12795	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ABW99_RS12800	COG2205	protein histidine kinase activity
ABW99_RS12805	COG0745	RESPONSE REGULATOR receiver
ABW99_RS12820	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ABW99_RS12830	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABW99_RS12850	COG0438	transferase activity, transferring glycosyl groups
ABW99_RS12880	COG0028	Belongs to the TPP enzyme family
ABW99_RS12885	COG0440	acetolactate synthase activity
ABW99_RS12895	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABW99_RS12900	COG0688	phosphatidylethanolamine metabolic process
ABW99_RS12905	COG1183	phosphatidylcholine synthase activity
ABW99_RS12910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABW99_RS12960	COG0589	response to stress
ABW99_RS12975	COG0415	Belongs to the DNA photolyase family
ABW99_RS12980	COG0300	oxidoreductase activity
ABW99_RS13000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ABW99_RS13010	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ABW99_RS13015	COG1309	transcriptional regulator
ABW99_RS13035	COG1846	Transcriptional regulator
ABW99_RS13040	COG1764	response to oxidative stress
ABW99_RS13065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABW99_RS13075	COG1595	DNA-templated transcription, initiation
ABW99_RS13080	COG0006	proline dipeptidase activity
ABW99_RS13085	COG0308	aminopeptidase N
ABW99_RS13095	COG1522	sequence-specific DNA binding
ABW99_RS13120	COG4178	(ABC) transporter
ABW99_RS13125	COG0312	modulator of DNA gyrase
ABW99_RS13130	COG0312	modulator of DNA gyrase
ABW99_RS13140	COG0492	ferredoxin-NADP+ reductase activity
ABW99_RS13155	COG0667	Aldo Keto reductase
ABW99_RS13160	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS13200	COG1024	Enoyl-CoA hydratase
ABW99_RS13210	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS13215	COG1562	ergosterol biosynthetic process
ABW99_RS13220	COG1657	PFAM Prenyltransferase squalene oxidase
ABW99_RS13235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABW99_RS13240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABW99_RS13270	COG2153	protein acetylation
ABW99_RS13275	COG0488	(ABC) transporter
ABW99_RS13300	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ABW99_RS13310	COG0583	DNA-binding transcription factor activity
ABW99_RS13315	COG2814	Major facilitator Superfamily
ABW99_RS13335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABW99_RS13340	COG0697	spore germination
ABW99_RS13355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABW99_RS13365	COG3161	chorismate lyase activity
ABW99_RS13395	COG3135	benzoate transporter
ABW99_RS13430	COG0778	Nitroreductase
ABW99_RS13435	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABW99_RS13440	COG2878	Part of a membrane complex involved in electron transport
ABW99_RS13445	COG1309	transcriptional regulator
ABW99_RS13460	COG0556	nucleotide-excision repair
ABW99_RS13470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABW99_RS13485	COG1104	cysteine desulfurase activity
ABW99_RS13490	COG0822	iron-sulfur transferase activity
ABW99_RS13495	COG0316	Belongs to the HesB IscA family
ABW99_RS13505	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ABW99_RS13520	COG2975	iron-sulfur cluster assembly
ABW99_RS13540	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ABW99_RS13550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABW99_RS13570	COG0084	hydrolase, TatD family'
ABW99_RS13575	COG2333	competence protein COMEC
ABW99_RS13575	COG0658	competence protein
ABW99_RS13580	COG2267	carboxylic ester hydrolase activity
ABW99_RS13585	COG0504	CTP synthase activity
ABW99_RS13590	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ABW99_RS13595	COG0148	phosphopyruvate hydratase activity
ABW99_RS13600	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ABW99_RS13610	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ABW99_RS13620	COG2833	Protein of unknown function (DUF455)
ABW99_RS13630	COG0613	PHP domain protein
ABW99_RS13635	COG0009	L-threonylcarbamoyladenylate synthase
ABW99_RS13640	COG1994	Peptidase M50
ABW99_RS13645	COG0180	Tryptophanyl-tRNA synthetase
ABW99_RS13655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABW99_RS13660	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ABW99_RS13665	COG0321	lipoyl(octanoyl) transferase activity
ABW99_RS13665	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ABW99_RS13680	COG2850	peptidyl-arginine hydroxylation
ABW99_RS13690	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABW99_RS13700	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABW99_RS13705	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABW99_RS13710	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ABW99_RS13730	COG0776	regulation of translation
ABW99_RS13745	COG0105	UTP biosynthetic process
ABW99_RS13765	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABW99_RS13770	COG0124	histidyl-tRNA synthetase
ABW99_RS13775	COG2976	Protein conserved in bacteria
ABW99_RS13780	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABW99_RS13790	COG1923	regulation of RNA biosynthetic process
ABW99_RS13795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ABW99_RS13800	COG0330	HflC and HflK could
ABW99_RS13805	COG0330	HflC and HflK could
ABW99_RS13815	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABW99_RS13825	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ABW99_RS13835	COG1959	2 iron, 2 sulfur cluster binding
ABW99_RS13845	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABW99_RS13850	COG4566	intracellular signal transduction
ABW99_RS13860	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ABW99_RS13865	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABW99_RS13875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABW99_RS13890	COG1686	Belongs to the peptidase S11 family
ABW99_RS13895	COG1414	Transcriptional regulator
ABW99_RS13910	COG0765	amino acid transport
ABW99_RS13915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS13920	COG0167	dihydroorotate dehydrogenase activity
ABW99_RS13925	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ABW99_RS13945	COG0583	DNA-binding transcription factor activity
ABW99_RS13970	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ABW99_RS13990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABW99_RS13995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ABW99_RS14000	COG0567	Dehydrogenase, E1 component
ABW99_RS14005	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABW99_RS14010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABW99_RS14015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ABW99_RS14030	COG5642	Protein of unknown function (DUF2384)
ABW99_RS14035	COG5654	RES domain protein
ABW99_RS14055	COG1846	Transcriptional regulator
ABW99_RS14075	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ABW99_RS14090	COG4964	Belongs to the GSP D family
ABW99_RS14140	COG3158	transport of potassium into the cell
ABW99_RS14145	COG1297	OPT oligopeptide transporter protein
ABW99_RS14150	COG0477	Major facilitator Superfamily
ABW99_RS14160	COG2183	response to ionizing radiation
ABW99_RS14175	COG1199	ATP-dependent helicase activity
ABW99_RS14185	COG0564	pseudouridine synthase activity
ABW99_RS14195	COG3243	poly(R)-hydroxyalkanoic acid synthase
ABW99_RS14200	COG0183	Belongs to the thiolase family
ABW99_RS14205	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS14215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABW99_RS14225	COG0183	Belongs to the thiolase family
ABW99_RS14255	COG0288	reversible hydration of carbon dioxide
ABW99_RS14260	COG0626	cystathionine gamma-synthase activity
ABW99_RS14265	COG0560	Phosphoserine phosphatase
ABW99_RS14300	COG0725	ABC transporter, periplasmic molybdate-binding protein
ABW99_RS14310	COG3842	ATPase activity
ABW99_RS14320	COG0625	glutathione transferase activity
ABW99_RS14335	COG3038	cytochrome b561
ABW99_RS14355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ABW99_RS14385	COG1686	Belongs to the peptidase S11 family
ABW99_RS14405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS14440	COG3038	cytochrome b561
ABW99_RS14460	COG3384	dioxygenase
ABW99_RS14470	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS14475	COG1902	pentaerythritol trinitrate reductase activity
ABW99_RS14480	COG0183	Belongs to the thiolase family
ABW99_RS14510	COG0840	transmembrane signaling receptor activity
ABW99_RS14515	COG5001	Diguanylate cyclase
ABW99_RS14520	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABW99_RS14525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ABW99_RS14540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABW99_RS14560	COG1522	sequence-specific DNA binding
ABW99_RS14575	COG2235	arginine
ABW99_RS14580	COG1982	Orn Lys Arg decarboxylase major
ABW99_RS14585	COG0531	amino acid
ABW99_RS14590	COG0477	Major facilitator Superfamily
ABW99_RS14595	COG2814	Major facilitator Superfamily
ABW99_RS14600	COG1902	pentaerythritol trinitrate reductase activity
ABW99_RS14635	COG2375	cellular response to nickel ion
ABW99_RS14650	COG1802	Transcriptional regulator
ABW99_RS14655	COG2271	Major facilitator Superfamily
ABW99_RS14665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ABW99_RS14690	COG2207	Transcriptional regulator
ABW99_RS14695	COG0583	DNA-binding transcription factor activity
ABW99_RS14700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS14705	COG1024	Enoyl-CoA hydratase
ABW99_RS14715	COG0477	Major facilitator Superfamily
ABW99_RS14720	COG0583	DNA-binding transcription factor activity
ABW99_RS14740	COG0583	DNA-binding transcription factor activity
ABW99_RS14755	COG2814	Major facilitator Superfamily
ABW99_RS14780	COG0583	DNA-binding transcription factor activity
ABW99_RS14790	COG0697	spore germination
ABW99_RS14795	COG0778	Nitroreductase
ABW99_RS14800	COG0583	DNA-binding transcription factor activity
ABW99_RS14805	COG1819	glycosyl
ABW99_RS14820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABW99_RS14825	COG2188	Transcriptional regulator
ABW99_RS14830	COG2814	Major facilitator Superfamily
ABW99_RS14850	COG0583	DNA-binding transcription factor activity
ABW99_RS14895	COG0346	lactoylglutathione lyase activity
ABW99_RS14900	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABW99_RS14905	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ABW99_RS14905	COG3261	NADH dehydrogenase
ABW99_RS14910	COG0651	ATP synthesis coupled electron transport
ABW99_RS14920	COG0650	Formate hydrogenlyase subunit 4
ABW99_RS14925	COG0651	ATP synthesis coupled electron transport
ABW99_RS14940	COG0129	dihydroxy-acid dehydratase activity
ABW99_RS14950	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ABW99_RS14970	COG0523	cobalamin synthesis protein
ABW99_RS15005	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABW99_RS15010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABW99_RS15035	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABW99_RS15060	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ABW99_RS15080	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABW99_RS15085	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ABW99_RS15105	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ABW99_RS15115	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ABW99_RS15120	COG4988	ABC transporter
ABW99_RS15130	COG1294	oxidase, subunit
ABW99_RS15135	COG1271	oxidase subunit
ABW99_RS15150	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS15160	COG0667	Aldo Keto reductase
ABW99_RS15170	COG0456	acetyltransferase
ABW99_RS15200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS15205	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABW99_RS15230	COG3344	reverse transcriptase
ABW99_RS15240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABW99_RS15245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABW99_RS15275	COG5001	Diguanylate cyclase
ABW99_RS15275	COG3300	MHYT domain
ABW99_RS15290	COG1522	sequence-specific DNA binding
ABW99_RS15300	COG0596	Alpha beta hydrolase
ABW99_RS15310	COG0583	DNA-binding transcription factor activity
ABW99_RS15315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABW99_RS15335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABW99_RS15350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ABW99_RS15355	COG0477	Major facilitator Superfamily
ABW99_RS15365	COG1595	DNA-templated transcription, initiation
ABW99_RS15380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ABW99_RS15390	COG4221	oxidoreductase activity
ABW99_RS15400	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ABW99_RS15405	COG4941	Belongs to the sigma-70 factor family
ABW99_RS15410	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ABW99_RS15415	COG3795	YCII-related domain
ABW99_RS15425	COG0640	Transcriptional regulator
ABW99_RS15480	COG1802	Transcriptional regulator
ABW99_RS15500	COG4572	Cation transport regulator
ABW99_RS15510	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ABW99_RS15515	COG3842	ATPase activity
ABW99_RS15520	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABW99_RS15525	COG1177	transmembrane transport
ABW99_RS15535	COG0456	acetyltransferase
ABW99_RS15535	COG1214	PFAM Peptidase M22, glycoprotease
ABW99_RS15545	COG0765	amino acid transport
ABW99_RS15550	COG1126	abc transporter atp-binding protein
ABW99_RS15560	COG0477	Major facilitator Superfamily
ABW99_RS15565	COG0154	amidase activity
ABW99_RS15580	COG1914	H( )-stimulated, divalent metal cation uptake system
ABW99_RS15625	COG0583	DNA-binding transcription factor activity
ABW99_RS15650	COG0589	response to stress
ABW99_RS15655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABW99_RS15690	COG2301	Belongs to the HpcH HpaI aldolase family
ABW99_RS15700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS15705	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS15715	COG2271	Major facilitator Superfamily
ABW99_RS15730	COG0671	phosphoesterase, PA-phosphatase related
ABW99_RS15735	COG0642	Histidine kinase
ABW99_RS15745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABW99_RS15775	COG2031	fatty acid transporter
ABW99_RS15790	COG0625	glutathione transferase activity
ABW99_RS15795	COG0024	Methionine aminopeptidase
ABW99_RS15810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABW99_RS15830	COG0667	Aldo Keto reductase
ABW99_RS15850	COG1309	transcriptional regulator
ABW99_RS15860	COG1294	oxidase, subunit
ABW99_RS15865	COG1271	oxidase subunit
ABW99_RS15875	COG3550	peptidyl-serine autophosphorylation
ABW99_RS15885	COG5001	Diguanylate cyclase
ABW99_RS15885	COG5002	protein histidine kinase activity
ABW99_RS15885	COG3447	MASE1 domain protein
ABW99_RS15920	COG0840	transmembrane signaling receptor activity
ABW99_RS15960	COG1309	transcriptional regulator
ABW99_RS15965	COG1979	alcohol dehydrogenase
ABW99_RS15990	COG0583	DNA-binding transcription factor activity
ABW99_RS16000	COG3795	YCII-related domain
ABW99_RS16030	COG3344	reverse transcriptase
ABW99_RS16035	COG0583	DNA-binding transcription factor activity
ABW99_RS16045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABW99_RS16065	COG0477	Major facilitator Superfamily
ABW99_RS16075	COG0583	DNA-binding transcription factor activity
ABW99_RS16090	COG0567	Dehydrogenase, E1 component
ABW99_RS16115	COG0123	including yeast histone deacetylase and acetoin utilization protein
ABW99_RS16140	COG1126	abc transporter atp-binding protein
ABW99_RS16145	COG0765	amino acid transport
ABW99_RS16155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS16180	COG2855	membrane
ABW99_RS16200	COG0477	Major facilitator Superfamily
ABW99_RS16220	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ABW99_RS16230	COG0655	NAD(P)H dehydrogenase (quinone) activity
ABW99_RS16285	COG4964	Belongs to the GSP D family
ABW99_RS16310	COG1414	Transcriptional regulator
ABW99_RS16320	COG2161	toxin-antitoxin pair type II binding
ABW99_RS16335	COG1024	Enoyl-CoA hydratase
ABW99_RS16345	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABW99_RS16350	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS16375	COG2885	chlorophyll binding
ABW99_RS16385	COG0477	Major facilitator Superfamily
ABW99_RS16390	COG1414	Transcriptional regulator
ABW99_RS16395	COG3246	L-lysine catabolic process to acetate
ABW99_RS16400	COG0511	ligase activity, forming carbon-carbon bonds
ABW99_RS16405	COG0439	Biotin carboxylase
ABW99_RS16420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS16425	COG1116	anion transmembrane transporter activity
ABW99_RS16425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABW99_RS16430	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS16450	COG3447	MASE1 domain protein
ABW99_RS16450	COG5001	Diguanylate cyclase
ABW99_RS16450	COG5002	protein histidine kinase activity
ABW99_RS16455	COG1024	Enoyl-CoA hydratase
ABW99_RS16465	COG3842	ATPase activity
ABW99_RS16470	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABW99_RS16475	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS16485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ABW99_RS16495	COG1802	Transcriptional regulator
ABW99_RS16505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS16515	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ABW99_RS16520	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ABW99_RS16540	COG0583	DNA-binding transcription factor activity
ABW99_RS16555	COG0583	DNA-binding transcription factor activity
ABW99_RS16565	COG0469	pyruvate kinase activity
ABW99_RS16575	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABW99_RS16580	COG0450	alkyl hydroperoxide reductase
ABW99_RS16600	COG1562	ergosterol biosynthetic process
ABW99_RS16615	COG0850	regulation of cytokinetic process
ABW99_RS16620	COG2894	cell division
ABW99_RS16625	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ABW99_RS16630	COG2267	carboxylic ester hydrolase activity
ABW99_RS16645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS16650	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABW99_RS16655	COG0740	serine-type endopeptidase activity
ABW99_RS16665	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABW99_RS16670	COG0776	regulation of translation
ABW99_RS16685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABW99_RS16695	COG4181	ATPase activity
ABW99_RS16700	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABW99_RS16700	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ABW99_RS16705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS16710	COG0047	phosphoribosylformylglycinamidine synthase activity
ABW99_RS16710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABW99_RS16715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABW99_RS16720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABW99_RS16730	COG2917	probably involved in intracellular septation
ABW99_RS16735	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABW99_RS16740	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ABW99_RS16745	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS16760	COG1335	isochorismatase
ABW99_RS16765	COG0183	Belongs to the thiolase family
ABW99_RS16780	COG2130	NADP-dependent
ABW99_RS16785	COG1454	alcohol dehydrogenase
ABW99_RS16790	COG0657	acetylesterase activity
ABW99_RS16795	COG1592	Rubrerythrin
ABW99_RS16800	COG0247	lactate metabolic process
ABW99_RS16820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABW99_RS16825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABW99_RS16885	COG0354	folic acid binding
ABW99_RS16890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABW99_RS16895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABW99_RS16905	COG1247	-acetyltransferase
ABW99_RS16910	COG0084	hydrolase, TatD family'
ABW99_RS16920	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ABW99_RS16935	COG1254	Belongs to the acylphosphatase family
ABW99_RS16955	COG1522	sequence-specific DNA binding
ABW99_RS16980	COG4638	Rieske (2fe-2S)
ABW99_RS17010	COG0783	Belongs to the Dps family
ABW99_RS17015	COG0045	succinate-CoA ligase (ADP-forming) activity
ABW99_RS17015	COG1042	CoA-binding domain protein
ABW99_RS17015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABW99_RS17020	COG0598	Magnesium transport protein CorA
ABW99_RS17025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABW99_RS17040	COG0735	belongs to the Fur family
ABW99_RS17045	COG3023	N-Acetylmuramoyl-L-alanine amidase
ABW99_RS17065	COG0583	DNA-binding transcription factor activity
ABW99_RS17070	COG0596	Alpha beta hydrolase
ABW99_RS17075	COG0038	chloride channel
ABW99_RS17080	COG3302	dmso reductase anchor subunit
ABW99_RS17085	COG0437	4 iron, 4 sulfur cluster binding
ABW99_RS17090	COG0243	molybdopterin cofactor binding
ABW99_RS17100	COG0277	FAD linked oxidase domain protein
ABW99_RS17110	COG0583	DNA-binding transcription factor activity
ABW99_RS17125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS17130	COG0765	amino acid transport
ABW99_RS17135	COG0765	amino acid transport
ABW99_RS17150	COG2188	Transcriptional regulator
ABW99_RS17155	COG2986	histidine ammonia-lyase
ABW99_RS17160	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ABW99_RS17170	COG1228	amidohydrolase
ABW99_RS17205	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABW99_RS17215	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS17220	COG3384	dioxygenase
ABW99_RS17230	COG3971	2-oxopent-4-enoate hydratase activity
ABW99_RS17240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABW99_RS17245	COG0730	response to heat
ABW99_RS17250	COG3258	Cytochrome c
ABW99_RS17255	COG2863	cytochrome
ABW99_RS17265	COG3453	Protein conserved in bacteria
ABW99_RS17265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABW99_RS17270	COG3459	Glycosyltransferase 36 associated
ABW99_RS17300	COG1215	transferase activity, transferring glycosyl groups
ABW99_RS17315	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ABW99_RS17405	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ABW99_RS17435	COG0166	Belongs to the GPI family
ABW99_RS17440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABW99_RS17455	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ABW99_RS17490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABW99_RS17495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ABW99_RS17500	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABW99_RS17500	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABW99_RS17510	COG0356	it plays a direct role in the translocation of protons across the membrane
ABW99_RS17525	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABW99_RS17530	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABW99_RS17535	COG3243	poly(R)-hydroxyalkanoic acid synthase
ABW99_RS17545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABW99_RS17570	COG0589	response to stress
ABW99_RS17580	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ABW99_RS17585	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS17640	COG0640	Transcriptional regulator
ABW99_RS17660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABW99_RS17670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABW99_RS17675	COG2326	polyphosphate kinase activity
ABW99_RS17685	COG1584	GPR1 FUN34 yaaH family protein
ABW99_RS17690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABW99_RS17695	COG2132	Multicopper oxidase
ABW99_RS17705	COG0463	Glycosyl transferase, family 2
ABW99_RS17725	COG1215	transferase activity, transferring glycosyl groups
ABW99_RS17730	COG1984	allophanate hydrolase subunit 2
ABW99_RS17735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ABW99_RS17750	COG0583	DNA-binding transcription factor activity
ABW99_RS17760	COG3842	ATPase activity
ABW99_RS17765	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABW99_RS17770	COG1177	transmembrane transport
ABW99_RS17800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABW99_RS17825	COG1566	PFAM secretion protein HlyD family protein
ABW99_RS17840	COG0811	peptide transport
ABW99_RS17845	COG0848	biopolymer transport protein
ABW99_RS17875	COG1538	Outer membrane efflux protein
ABW99_RS17880	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABW99_RS17925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ABW99_RS17930	COG0477	Major facilitator Superfamily
ABW99_RS17935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABW99_RS17950	COG0438	transferase activity, transferring glycosyl groups
ABW99_RS17980	COG0739	heme binding
ABW99_RS17990	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABW99_RS17995	COG1228	amidohydrolase
ABW99_RS18000	COG0523	cobalamin synthesis protein
ABW99_RS18005	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ABW99_RS18045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ABW99_RS18070	COG0583	DNA-binding transcription factor activity
ABW99_RS18075	COG3618	amidohydrolase
ABW99_RS18085	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ABW99_RS18095	COG0523	cobalamin synthesis protein
ABW99_RS18100	COG2233	PERMEase
ABW99_RS18110	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS18135	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABW99_RS18140	COG1172	Belongs to the binding-protein-dependent transport system permease family
ABW99_RS18145	COG4191	Histidine kinase
ABW99_RS18160	COG1802	Transcriptional regulator
ABW99_RS18170	COG2020	methyltransferase activity
ABW99_RS18175	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ABW99_RS18205	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ABW99_RS18215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABW99_RS18220	COG3394	polysaccharide catabolic process
ABW99_RS18235	COG2223	nitrite transmembrane transporter activity
ABW99_RS18245	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ABW99_RS18250	COG3383	formate dehydrogenase (NAD+) activity
ABW99_RS18325	COG3842	ATPase activity
ABW99_RS18335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABW99_RS18350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ABW99_RS18350	COG2010	Cytochrome c
ABW99_RS18360	COG0583	DNA-binding transcription factor activity
ABW99_RS18370	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABW99_RS18375	COG3842	ATPase activity
ABW99_RS18380	COG1177	transmembrane transport
ABW99_RS18385	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ABW99_RS18395	COG1609	Transcriptional regulator
ABW99_RS18420	COG3706	GGDEF domain
ABW99_RS18440	COG0488	(ABC) transporter
ABW99_RS18455	COG0583	DNA-binding transcription factor activity
ABW99_RS18465	COG2233	PERMEase
ABW99_RS18510	COG1113	amino acid transport
ABW99_RS18520	COG4266	Belongs to the allantoicase family
ABW99_RS18535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS18545	COG1953	Uracil, thiamine, allantoin
ABW99_RS18550	COG2186	Transcriptional regulator
ABW99_RS18555	COG0840	transmembrane signaling receptor activity
ABW99_RS18560	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABW99_RS18580	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS18585	COG0798	PFAM Bile acid sodium symporter
ABW99_RS18590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABW99_RS18615	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS18645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABW99_RS18645	COG0519	Catalyzes the synthesis of GMP from XMP
ABW99_RS18665	COG2914	Belongs to the UPF0125 (RnfH) family
ABW99_RS18670	COG2867	negative regulation of translational initiation
ABW99_RS18675	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABW99_RS18680	COG0330	HflC and HflK could
ABW99_RS18695	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ABW99_RS18700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABW99_RS18710	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABW99_RS18715	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABW99_RS18725	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABW99_RS18730	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ABW99_RS18740	COG0750	zinc metalloprotease
ABW99_RS18755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABW99_RS18765	COG0528	UMP kinase activity
ABW99_RS18770	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ABW99_RS18775	COG0052	Belongs to the universal ribosomal protein uS2 family
ABW99_RS18780	COG0024	Methionine aminopeptidase
ABW99_RS18790	COG1187	pseudouridine synthase activity
ABW99_RS18795	COG0242	peptide deformylase activity
ABW99_RS18800	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABW99_RS18825	COG2171	N-acyltransferase activity
ABW99_RS18830	COG1393	Belongs to the ArsC family
ABW99_RS18840	COG2890	protein-(glutamine-N5) methyltransferase activity
ABW99_RS18845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABW99_RS18850	COG0488	(ABC) transporter
ABW99_RS18860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABW99_RS18865	COG0477	Major facilitator Superfamily
ABW99_RS18870	COG0351	phosphomethylpyrimidine kinase
ABW99_RS18880	COG1573	uracil-dna glycosylase
ABW99_RS18890	COG1214	PFAM Peptidase M22, glycoprotease
ABW99_RS18895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS18900	COG0765	amino acid transport
ABW99_RS18905	COG0765	amino acid transport
ABW99_RS18910	COG1126	abc transporter atp-binding protein
ABW99_RS18915	COG5285	phytanoyl-CoA dioxygenase
ABW99_RS18920	COG0662	Cupin 2, conserved barrel domain protein
ABW99_RS18940	COG0513	Belongs to the DEAD box helicase family
ABW99_RS18945	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ABW99_RS18955	COG0583	DNA-binding transcription factor activity
ABW99_RS18960	COG0589	response to stress
ABW99_RS18965	COG2224	Isocitrate lyase
ABW99_RS18970	COG0697	spore germination
ABW99_RS18980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABW99_RS18985	COG0583	DNA-binding transcription factor activity
ABW99_RS19010	COG0542	response to heat
ABW99_RS19015	COG2346	COG2346, Truncated hemoglobins
ABW99_RS19020	COG0314	molybdopterin synthase activity
ABW99_RS19030	COG0303	'Molybdopterin
ABW99_RS19035	COG1573	uracil-dna glycosylase
ABW99_RS19050	COG0436	Aminotransferase
ABW99_RS19065	COG2076	Multidrug Resistance protein
ABW99_RS19070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABW99_RS19075	COG0463	Glycosyl transferase, family 2
ABW99_RS19090	COG0726	polysaccharide deacetylase
ABW99_RS19095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABW99_RS19100	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ABW99_RS19105	COG0791	NLP P60 protein
ABW99_RS19115	COG0359	binds to the 23S rRNA
ABW99_RS19135	COG0583	DNA-binding transcription factor activity
ABW99_RS19140	COG3960	tartronate-semialdehyde synthase activity
ABW99_RS19145	COG3622	Belongs to the hyi family
ABW99_RS19150	COG2084	Dehydrogenase
ABW99_RS19160	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ABW99_RS19170	COG0252	asparaginase activity
ABW99_RS19175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABW99_RS19185	COG1024	Enoyl-CoA hydratase
ABW99_RS19190	COG1217	gtp-binding protein TYPA
ABW99_RS19205	COG1566	PFAM secretion protein HlyD family protein
ABW99_RS19210	COG2814	Major facilitator Superfamily
ABW99_RS19215	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABW99_RS19225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABW99_RS19230	COG2251	uridine kinase activity
ABW99_RS19230	COG0195	Participates in both transcription termination and antitermination
ABW99_RS19235	COG0779	Required for maturation of 30S ribosomal subunits
ABW99_RS19240	COG1187	pseudouridine synthase activity
ABW99_RS19245	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ABW99_RS19250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABW99_RS19255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABW99_RS19275	COG1643	Atp-dependent helicase
ABW99_RS19280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABW99_RS19280	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ABW99_RS19285	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ABW99_RS19295	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ABW99_RS19305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABW99_RS19310	COG0557	exoribonuclease II activity
ABW99_RS19325	COG0573	inorganic phosphate transmembrane transporter activity
ABW99_RS19350	COG0066	3-isopropylmalate dehydratase activity
ABW99_RS19355	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABW99_RS19360	COG0583	DNA-binding transcription factor activity
ABW99_RS19365	COG2814	Major facilitator Superfamily
ABW99_RS19390	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABW99_RS19415	COG0473	3-isopropylmalate dehydrogenase activity
ABW99_RS19420	COG0583	DNA-binding transcription factor activity
ABW99_RS19425	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ABW99_RS19425	COG2755	lipolytic protein G-D-S-L family
ABW99_RS19435	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ABW99_RS19440	COG2818	Glycosylase
ABW99_RS19445	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABW99_RS19460	COG0745	RESPONSE REGULATOR receiver
ABW99_RS19465	COG0745	RESPONSE REGULATOR receiver
ABW99_RS19485	COG2204	response regulator
ABW99_RS19495	COG0174	glutamine synthetase
ABW99_RS19570	COG2186	Transcriptional regulator
ABW99_RS19575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABW99_RS19580	COG3395	kinase activity
ABW99_RS19585	COG0235	Class ii aldolase
ABW99_RS19590	COG0477	Major facilitator Superfamily
ABW99_RS19625	COG2814	Major facilitator Superfamily
ABW99_RS19655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABW99_RS19660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABW99_RS19720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABW99_RS19765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABW99_RS19770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABW99_RS19780	COG0183	Belongs to the thiolase family
ABW99_RS19785	COG1414	Transcriptional regulator
ABW99_RS19790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABW99_RS19825	COG0110	maltose O-acetyltransferase activity
ABW99_RS19855	COG1335	isochorismatase
ABW99_RS19895	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS19920	COG2207	Transcriptional regulator
ABW99_RS19930	COG0477	Major facilitator Superfamily
ABW99_RS19940	COG0235	Class ii aldolase
ABW99_RS19950	COG1064	alcohol dehydrogenase
ABW99_RS19955	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS19960	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ABW99_RS19975	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS19980	COG0583	DNA-binding transcription factor activity
ABW99_RS19985	COG2814	Major facilitator Superfamily
ABW99_RS19990	COG0583	DNA-binding transcription factor activity
ABW99_RS20015	COG0583	DNA-binding transcription factor activity
ABW99_RS20030	COG1136	(ABC) transporter
ABW99_RS20030	COG0577	efflux transmembrane transporter activity
ABW99_RS20035	COG0577	efflux transmembrane transporter activity
ABW99_RS20035	COG1136	(ABC) transporter
ABW99_RS20065	COG0574	Belongs to the PEP-utilizing enzyme family
ABW99_RS20065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABW99_RS20075	COG0058	SHG alpha-glucan phosphorylase activity
ABW99_RS20105	COG0298	carbon dioxide binding
ABW99_RS20110	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ABW99_RS20135	COG0543	2 iron, 2 sulfur cluster binding
ABW99_RS20160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABW99_RS20165	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABW99_RS20180	COG0277	FAD linked oxidase domain protein
ABW99_RS20190	COG4977	sequence-specific DNA binding
ABW99_RS20225	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ABW99_RS20230	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ABW99_RS20280	COG2204	response regulator
ABW99_RS20290	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABW99_RS20310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ABW99_RS20315	COG1840	ABC-type Fe3 transport system, periplasmic component
ABW99_RS20320	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABW99_RS20325	COG0791	NLP P60 protein
ABW99_RS20330	COG4172	Belongs to the ABC transporter superfamily
ABW99_RS20335	COG4239	(ABC) transporter, permease
ABW99_RS20340	COG4174	ABC transporter (Permease)
ABW99_RS20345	COG4166	transmembrane transport
ABW99_RS20365	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS20370	COG4689	acetoacetate decarboxylase
ABW99_RS20375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS20400	COG0583	DNA-binding transcription factor activity
ABW99_RS20405	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ABW99_RS20420	COG0527	aspartate kinase activity
ABW99_RS20425	COG0037	tRNA processing
ABW99_RS20430	COG0825	malonyl-CoA metabolic process
ABW99_RS20435	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ABW99_RS20440	COG0215	cysteine-tRNA ligase activity
ABW99_RS20450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABW99_RS20455	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABW99_RS20460	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABW99_RS20465	COG1045	serine acetyltransferase
ABW99_RS20475	COG0483	inositol monophosphate 1-phosphatase activity
ABW99_RS20485	COG4977	sequence-specific DNA binding
ABW99_RS20490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABW99_RS20515	COG0285	dihydrofolate synthase activity
ABW99_RS20520	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ABW99_RS20525	COG0159	tryptophan synthase activity
ABW99_RS20535	COG0133	tryptophan synthase activity
ABW99_RS20540	COG0135	phosphoribosylanthranilate isomerase activity
ABW99_RS20545	COG0101	tRNA pseudouridine synthase activity
ABW99_RS20555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABW99_RS20560	COG0473	3-isopropylmalate dehydrogenase activity
ABW99_RS20575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABW99_RS20580	COG0372	Belongs to the citrate synthase family
ABW99_RS20585	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH