locus-tag	class	description
ABW99_RS00005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ABW99_RS00010	COG0594	ribonuclease P activity
ABW99_RS00020	COG0706	membrane insertase activity
ABW99_RS00025	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABW99_RS00030	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ABW99_RS00040	COG2814	Major facilitator Superfamily
ABW99_RS00050	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ABW99_RS00050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS00085	COG2154	pterin-4-alpha-carbinolamine dehydratase
ABW99_RS00100	COG2423	ornithine cyclodeaminase activity
ABW99_RS00105	COG0583	DNA-binding transcription factor activity
ABW99_RS00115	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS00120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABW99_RS00135	COG1473	amidohydrolase
ABW99_RS00140	COG1802	Transcriptional regulator
ABW99_RS00145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS00160	COG0367	asparagine synthase
ABW99_RS00165	COG1522	sequence-specific DNA binding
ABW99_RS00175	COG0114	fumarate hydratase activity
ABW99_RS00180	COG0583	DNA-binding transcription factor activity
ABW99_RS00210	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABW99_RS00215	COG1172	Belongs to the binding-protein-dependent transport system permease family
ABW99_RS00225	COG1846	Transcriptional regulator
ABW99_RS00245	COG2070	2-Nitropropane dioxygenase
ABW99_RS00250	COG0445	tRNA wobble uridine modification
ABW99_RS00265	COG1192	Involved in chromosome partitioning
ABW99_RS00270	COG1475	DNA binding
ABW99_RS00275	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABW99_RS00285	COG0356	it plays a direct role in the translocation of protons across the membrane
ABW99_RS00295	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABW99_RS00300	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABW99_RS00310	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABW99_RS00315	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABW99_RS00320	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABW99_RS00335	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS00355	COG1360	Flagellar Motor Protein
ABW99_RS00360	COG0745	RESPONSE REGULATOR receiver
ABW99_RS00365	COG2198	Histidine kinase
ABW99_RS00365	COG0643	Histidine kinase
ABW99_RS00370	COG0835	chemotaxis
ABW99_RS00375	COG0840	transmembrane signaling receptor activity
ABW99_RS00375	COG0840	transmembrane signaling receptor activity
ABW99_RS00380	COG0840	transmembrane signaling receptor activity
ABW99_RS00390	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ABW99_RS00395	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ABW99_RS00405	COG0745	RESPONSE REGULATOR receiver
ABW99_RS00410	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ABW99_RS00415	COG0667	Aldo Keto reductase
ABW99_RS00420	COG0583	DNA-binding transcription factor activity
ABW99_RS00430	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABW99_RS00445	COG1191	sigma factor activity
ABW99_RS00470	COG1558	bacterial-type flagellum-dependent cell motility
ABW99_RS00485	COG4787	bacterial-type flagellum-dependent cell motility
ABW99_RS00495	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ABW99_RS00500	COG1706	bacterial-type flagellum-dependent cell motility
ABW99_RS00505	COG3951	Flagellar rod assembly protein muramidase FlgJ
ABW99_RS00505	COG1705	Flagellar rod assembly protein muramidase FlgJ
ABW99_RS00510	COG1256	bacterial-type flagellum assembly
ABW99_RS00530	COG1338	Plays a role in the flagellum-specific transport system
ABW99_RS00535	COG3190	flagellar
ABW99_RS00550	COG1580	Controls the rotational direction of flagella during chemotaxis
ABW99_RS00585	COG1677	Flagellar hook-basal body complex protein FliE
ABW99_RS00590	COG2257	FlhB HrpN YscU SpaS Family
ABW99_RS00610	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ABW99_RS00650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS00670	COG2828	Protein conserved in bacteria
ABW99_RS00685	COG3245	cytochrome
ABW99_RS00690	COG0210	DNA helicase
ABW99_RS00705	COG0509	glycine decarboxylation via glycine cleavage system
ABW99_RS00710	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABW99_RS00710	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABW99_RS00715	COG1760	l-serine dehydratase
ABW99_RS00725	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS00730	COG0028	Belongs to the TPP enzyme family
ABW99_RS00735	COG0583	DNA-binding transcription factor activity
ABW99_RS00740	COG0477	Major facilitator Superfamily
ABW99_RS00750	COG0506	proline dehydrogenase activity
ABW99_RS00750	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ABW99_RS00750	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ABW99_RS00755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABW99_RS00770	COG0657	acetylesterase activity
ABW99_RS00775	COG1832	CoA-binding protein
ABW99_RS00780	COG3622	Belongs to the hyi family
ABW99_RS00805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABW99_RS00815	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ABW99_RS00820	COG0792	nuclease activity
ABW99_RS00825	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ABW99_RS00830	COG2823	Periplasmic or secreted lipoprotein
ABW99_RS00845	COG3047	cAMP biosynthetic process
ABW99_RS00875	COG0583	DNA-binding transcription factor activity
ABW99_RS00885	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS00890	COG0443	Heat shock 70 kDa protein
ABW99_RS00895	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ABW99_RS00900	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABW99_RS00915	COG2233	PERMEase
ABW99_RS00920	COG0513	Belongs to the DEAD box helicase family
ABW99_RS00925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ABW99_RS00940	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABW99_RS00945	COG1763	Mo-molybdopterin cofactor biosynthetic process
ABW99_RS00950	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABW99_RS00955	COG2814	Major facilitator Superfamily
ABW99_RS00960	COG0280	phosphate acetyltransferase
ABW99_RS00960	COG0281	malic enzyme
ABW99_RS00980	COG1522	sequence-specific DNA binding
ABW99_RS01005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABW99_RS01010	COG2151	metal-sulfur cluster biosynthetic enzyme
ABW99_RS01015	COG3396	Phenylacetate-CoA oxygenase
ABW99_RS01020	COG3460	Phenylacetate-CoA oxygenase
ABW99_RS01025	COG3396	Phenylacetate-CoA oxygenase
ABW99_RS01080	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABW99_RS01095	COG0081	regulation of translation
ABW99_RS01105	COG0222	ribosome binding
ABW99_RS01110	COG0085	RNA polymerase activity
ABW99_RS01120	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABW99_RS01125	COG0049	tRNA binding
ABW99_RS01140	COG0051	transcription antitermination factor activity, RNA binding
ABW99_RS01145	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABW99_RS01155	COG0089	rRNA binding
ABW99_RS01160	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABW99_RS01170	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ABW99_RS01175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABW99_RS01180	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABW99_RS01185	COG0255	Belongs to the universal ribosomal protein uL29 family
ABW99_RS01190	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABW99_RS01195	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABW99_RS01200	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABW99_RS01205	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ABW99_RS01220	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABW99_RS01225	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ABW99_RS01230	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABW99_RS01240	COG0200	Binds to the 23S rRNA
ABW99_RS01245	COG0201	protein transport
ABW99_RS01255	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ABW99_RS01260	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABW99_RS01265	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ABW99_RS01270	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABW99_RS01275	COG0202	RNA polymerase activity
ABW99_RS01290	COG4232	protein-disulfide reductase activity
ABW99_RS01300	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABW99_RS01310	COG1333	cytochrome c biogenesis protein
ABW99_RS01315	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABW99_RS01320	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABW99_RS01325	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ABW99_RS01340	COG1965	Belongs to the frataxin family
ABW99_RS01380	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABW99_RS01385	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ABW99_RS01390	COG4575	ribosome binding
ABW99_RS01395	COG3047	cAMP biosynthetic process
ABW99_RS01400	COG3047	cAMP biosynthetic process
ABW99_RS01410	COG0069	glutamate synthase activity
ABW99_RS01410	COG0070	glutamate synthase
ABW99_RS01410	COG0067	glutamate synthase
ABW99_RS01420	COG4178	(ABC) transporter
ABW99_RS01445	COG1127	ABC transporter
ABW99_RS01450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABW99_RS01455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ABW99_RS01460	COG2853	Lipoprotein
ABW99_RS01475	COG1131	(ABC) transporter
ABW99_RS01480	COG0842	Transport permease protein
ABW99_RS01490	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABW99_RS01500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABW99_RS01510	COG0131	Imidazoleglycerol-phosphate dehydratase
ABW99_RS01515	COG2095	MarC family integral membrane protein
ABW99_RS01525	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABW99_RS01535	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABW99_RS01540	COG0140	phosphoribosyl-ATP diphosphatase activity
ABW99_RS01555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABW99_RS01565	COG0805	protein transport
ABW99_RS01570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABW99_RS01575	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABW99_RS01580	COG1970	mechanosensitive ion channel activity
ABW99_RS01585	COG0723	plastoquinol--plastocyanin reductase activity
ABW99_RS01590	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ABW99_RS01595	COG2857	Cytochrome c1
ABW99_RS01600	COG0625	glutathione transferase activity
ABW99_RS01605	COG2969	positive regulation of protein catabolic process
ABW99_RS01615	COG0625	glutathione transferase activity
ABW99_RS01635	COG2308	Evidence 4 Homologs of previously reported genes of
ABW99_RS01655	COG0583	DNA-binding transcription factor activity
ABW99_RS01660	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ABW99_RS01665	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS01690	COG1538	Outer membrane efflux protein
ABW99_RS01700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABW99_RS01710	COG0583	DNA-binding transcription factor activity
ABW99_RS01715	COG0004	ammonium transporteR
ABW99_RS01735	COG0163	prenyltransferase activity
ABW99_RS01740	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ABW99_RS01745	COG2890	protein-(glutamine-N5) methyltransferase activity
ABW99_RS01755	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABW99_RS01760	COG2261	transglycosylase associated protein
ABW99_RS01770	COG0488	(ABC) transporter
ABW99_RS01775	COG0012	GTP binding
ABW99_RS01780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABW99_RS01795	COG0583	DNA-binding transcription factor activity
ABW99_RS01810	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABW99_RS01820	COG0134	indole-3-glycerol-phosphate synthase activity
ABW99_RS01825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABW99_RS01840	COG0546	phosphoglycolate phosphatase activity
ABW99_RS01845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABW99_RS01850	COG2967	ApaG domain
ABW99_RS01855	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ABW99_RS01865	COG2050	protein possibly involved in aromatic compounds catabolism
ABW99_RS01870	COG1024	Enoyl-CoA hydratase
ABW99_RS01875	COG0183	Belongs to the thiolase family
ABW99_RS01885	COG1024	Enoyl-CoA hydratase
ABW99_RS01915	COG1473	amidohydrolase
ABW99_RS01920	COG0243	molybdopterin cofactor binding
ABW99_RS01935	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS01940	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ABW99_RS01945	COG2001	Belongs to the MraZ family
ABW99_RS01950	COG0275	rRNA processing
ABW99_RS01955	COG3116	cell division
ABW99_RS01965	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABW99_RS01970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ABW99_RS02000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABW99_RS02005	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABW99_RS02010	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ABW99_RS02020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABW99_RS02035	COG0653	protein targeting
ABW99_RS02050	COG0494	nUDIX hydrolase
ABW99_RS02055	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ABW99_RS02060	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ABW99_RS02085	COG4536	flavin adenine dinucleotide binding
ABW99_RS02095	COG0142	geranyltranstransferase activity
ABW99_RS02100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABW99_RS02105	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ABW99_RS02110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABW99_RS02135	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ABW99_RS02140	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABW99_RS02145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABW99_RS02160	COG3023	N-Acetylmuramoyl-L-alanine amidase
ABW99_RS02195	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ABW99_RS02210	COG0439	Biotin carboxylase
ABW99_RS02215	COG0511	ligase activity, forming carbon-carbon bonds
ABW99_RS02220	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ABW99_RS02235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABW99_RS02240	COG3150	esterase
ABW99_RS02255	COG0632	four-way junction helicase activity
ABW99_RS02265	COG1981	membrane
ABW99_RS02275	COG0800	Aldolase
ABW99_RS02285	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABW99_RS02310	COG0482	sulfurtransferase activity
ABW99_RS02315	COG0069	glutamate synthase activity
ABW99_RS02320	COG0625	glutathione transferase activity
ABW99_RS02330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ABW99_RS02335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABW99_RS02340	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABW99_RS02345	COG1862	Preprotein translocase
ABW99_RS02350	COG0343	queuine tRNA-ribosyltransferase activity
ABW99_RS02355	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABW99_RS02360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ABW99_RS02370	COG0583	DNA-binding transcription factor activity
ABW99_RS02375	COG0783	Belongs to the Dps family
ABW99_RS02380	COG3344	reverse transcriptase
ABW99_RS02400	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ABW99_RS02420	COG0386	Belongs to the glutathione peroxidase family
ABW99_RS02425	COG1346	cytolysis
ABW99_RS02430	COG1380	Effector of murein hydrolase LrgA
ABW99_RS02435	COG0247	lactate metabolic process
ABW99_RS02440	COG0277	FAD linked oxidase domain protein
ABW99_RS02445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABW99_RS02450	COG0277	FAD linked oxidase domain protein
ABW99_RS02455	COG0277	FAD linked oxidase domain protein
ABW99_RS02460	COG2096	Adenosyltransferase
ABW99_RS02465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ABW99_RS02470	COG0312	modulator of DNA gyrase
ABW99_RS02475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABW99_RS02485	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ABW99_RS02490	COG0497	DNA recombination
ABW99_RS02500	COG1420	regulation of RNA biosynthetic process
ABW99_RS02510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABW99_RS02520	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ABW99_RS02525	COG0443	Heat shock 70 kDa protein
ABW99_RS02530	COG0484	heat shock protein binding
ABW99_RS02535	COG0512	Glutamine amidotransferase of anthranilate synthase
ABW99_RS02535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABW99_RS02540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ABW99_RS02545	COG1428	Deoxynucleoside kinase
ABW99_RS02550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ABW99_RS02565	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABW99_RS02570	COG0628	permease
ABW99_RS02585	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ABW99_RS02590	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ABW99_RS02595	COG0586	Pfam SNARE associated Golgi protein
ABW99_RS02600	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABW99_RS02605	COG0802	atpase or kinase
ABW99_RS02610	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ABW99_RS02615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABW99_RS02620	COG4974	Belongs to the 'phage' integrase family
ABW99_RS02625	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS02635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ABW99_RS02640	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ABW99_RS02655	COG3123	guanosine phosphorylase activity
ABW99_RS02660	COG0137	argininosuccinate synthase activity
ABW99_RS02665	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABW99_RS02675	COG0268	Binds directly to 16S ribosomal RNA
ABW99_RS02680	COG0728	peptidoglycan biosynthetic process
ABW99_RS02685	COG2912	Transglutaminase-like superfamily
ABW99_RS02700	COG0563	adenylate kinase activity
ABW99_RS02705	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ABW99_RS02725	COG0811	peptide transport
ABW99_RS02730	COG1570	exodeoxyribonuclease VII activity
ABW99_RS02735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABW99_RS02760	COG1278	Cold shock
ABW99_RS02765	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ABW99_RS02770	COG0542	response to heat
ABW99_RS02775	COG0756	dUTP diphosphatase activity
ABW99_RS02780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABW99_RS02785	COG2814	Major facilitator Superfamily
ABW99_RS02795	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ABW99_RS02800	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABW99_RS02805	COG0196	riboflavin kinase activity
ABW99_RS02810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ABW99_RS02815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABW99_RS02815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ABW99_RS02820	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ABW99_RS02820	COG3264	Mechanosensitive ion channel
ABW99_RS02830	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ABW99_RS02840	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ABW99_RS02850	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ABW99_RS02855	COG2003	Belongs to the UPF0758 family
ABW99_RS02860	COG1047	Peptidyl-prolyl cis-trans
ABW99_RS02865	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ABW99_RS02885	COG0411	ABC transporter
ABW99_RS02900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABW99_RS02905	COG0543	2 iron, 2 sulfur cluster binding
ABW99_RS02905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABW99_RS02950	COG3237	CsbD-like
ABW99_RS02955	COG4585	Histidine kinase
ABW99_RS02970	COG2197	response regulator
ABW99_RS02975	COG2201	protein-glutamate methylesterase activity
ABW99_RS02980	COG5001	Diguanylate cyclase
ABW99_RS02980	COG3300	MHYT domain
ABW99_RS02990	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ABW99_RS02995	COG0741	lytic transglycosylase activity
ABW99_RS03000	COG0436	Aminotransferase
ABW99_RS03005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABW99_RS03010	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABW99_RS03020	COG4336	lyase activity
ABW99_RS03025	COG0583	DNA-binding transcription factor activity
ABW99_RS03035	COG0583	DNA-binding transcription factor activity
ABW99_RS03075	COG0506	proline dehydrogenase activity
ABW99_RS03085	COG1686	Belongs to the peptidase S11 family
ABW99_RS03095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABW99_RS03095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABW99_RS03110	COG1704	LemA family
ABW99_RS03115	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABW99_RS03120	COG0671	phosphoesterase, PA-phosphatase related
ABW99_RS03125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ABW99_RS03135	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ABW99_RS03145	COG1737	Transcriptional regulator
ABW99_RS03145	COG0837	glucose binding
ABW99_RS03150	COG3360	Dodecin
ABW99_RS03155	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABW99_RS03165	COG2181	nitrate reductase activity
ABW99_RS03170	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ABW99_RS03175	COG1140	nitrate reductase beta subunit
ABW99_RS03180	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ABW99_RS03190	COG1017	nitric oxide dioxygenase activity
ABW99_RS03190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABW99_RS03215	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABW99_RS03220	COG1116	anion transmembrane transporter activity
ABW99_RS03225	COG0640	Transcriptional regulator
ABW99_RS03245	COG0477	Major facilitator Superfamily
ABW99_RS03250	COG0477	Major facilitator Superfamily
ABW99_RS03255	COG0531	amino acid
ABW99_RS03265	COG0583	DNA-binding transcription factor activity
ABW99_RS03280	COG4977	sequence-specific DNA binding
ABW99_RS03285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS03290	COG0765	amino acid transport
ABW99_RS03295	COG1126	abc transporter atp-binding protein
ABW99_RS03300	COG0252	asparaginase activity
ABW99_RS03325	COG0457	Tetratricopeptide repeat
ABW99_RS03335	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS03340	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS03375	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ABW99_RS03385	COG0315	cyclic pyranopterin monophosphate synthase activity
ABW99_RS03395	COG0429	hydrolase of the alpha beta-hydrolase fold
ABW99_RS03430	COG0126	phosphoglycerate kinase activity
ABW99_RS03435	COG0469	pyruvate kinase activity
ABW99_RS03445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABW99_RS03450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABW99_RS03455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ABW99_RS03460	COG0009	L-threonylcarbamoyladenylate synthase
ABW99_RS03475	COG2027	D-alanyl-D-alanine carboxypeptidase
ABW99_RS03485	COG0642	Histidine kinase
ABW99_RS03490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABW99_RS03500	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ABW99_RS03500	COG3608	succinylglutamate desuccinylase aspartoacylase
ABW99_RS03540	COG1309	transcriptional regulator
ABW99_RS03545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABW99_RS03550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABW99_RS03585	COG4970	Tfp pilus assembly protein FimT
ABW99_RS03610	COG4575	ribosome binding
ABW99_RS03615	COG0450	alkyl hydroperoxide reductase
ABW99_RS03620	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS03630	COG3483	tryptophan 2,3-dioxygenase activity
ABW99_RS03640	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ABW99_RS03645	COG1522	sequence-specific DNA binding
ABW99_RS03655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABW99_RS03660	COG2309	aminopeptidase activity
ABW99_RS03665	COG0596	Alpha beta hydrolase
ABW99_RS03680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABW99_RS03690	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ABW99_RS03695	COG0259	pyridoxamine-phosphate oxidase activity
ABW99_RS03700	COG2982	Protein involved in outer membrane biogenesis
ABW99_RS03705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ABW99_RS03710	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS03725	COG0028	Belongs to the TPP enzyme family
ABW99_RS03800	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS03810	COG0778	Nitroreductase
ABW99_RS03825	COG2409	Drug exporters of the RND superfamily
ABW99_RS03840	COG2207	Transcriptional regulator
ABW99_RS03855	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABW99_RS03860	COG1845	cytochrome c oxidase, subunit III
ABW99_RS03865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABW99_RS03870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ABW99_RS03875	COG0477	Major facilitator Superfamily
ABW99_RS03880	COG3002	Belongs to the UPF0753 family
ABW99_RS03885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABW99_RS03890	COG0583	DNA-binding transcription factor activity
ABW99_RS03905	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABW99_RS03915	COG0842	Transport permease protein
ABW99_RS03920	COG0842	Transport permease protein
ABW99_RS03920	COG1129	ABC transporter
ABW99_RS03925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABW99_RS03940	COG1560	Kdo2-lipid A biosynthetic process
ABW99_RS03975	COG4633	Protein conserved in bacteria
ABW99_RS04035	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABW99_RS04050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABW99_RS04060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABW99_RS04185	COG4372	Transposase
ABW99_RS04195	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABW99_RS04235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABW99_RS04250	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABW99_RS04265	COG0420	3'-5' exonuclease activity
ABW99_RS04335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABW99_RS04355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ABW99_RS04370	COG3328	transposase activity
ABW99_RS04420	COG0583	DNA-binding transcription factor activity
ABW99_RS04430	COG2159	amidohydrolase
ABW99_RS04485	COG1139	Iron-sulfur cluster binding protein
ABW99_RS04495	COG0247	lactate metabolic process
ABW99_RS04500	COG2186	Transcriptional regulator
ABW99_RS04505	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ABW99_RS04515	COG0302	gtp cyclohydrolase
ABW99_RS04535	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ABW99_RS04540	COG5001	Diguanylate cyclase
ABW99_RS04545	COG1024	Enoyl-CoA hydratase
ABW99_RS04550	COG3300	MHYT domain
ABW99_RS04550	COG5001	Diguanylate cyclase
ABW99_RS04575	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABW99_RS04615	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ABW99_RS04620	COG1802	Transcriptional regulator
ABW99_RS04625	COG2814	Major facilitator Superfamily
ABW99_RS04640	COG1113	amino acid transport
ABW99_RS04650	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS04655	COG0436	Aminotransferase
ABW99_RS04685	COG2916	Histone family protein nucleoid-structuring protein H-NS
ABW99_RS04700	COG2197	response regulator
ABW99_RS04710	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ABW99_RS04715	COG1074	ATP-dependent DNA helicase activity
ABW99_RS04720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABW99_RS04730	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABW99_RS04735	COG1278	Cold shock
ABW99_RS04745	COG1253	flavin adenine dinucleotide binding
ABW99_RS04750	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ABW99_RS04760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABW99_RS04765	COG0840	transmembrane signaling receptor activity
ABW99_RS04780	COG0513	Belongs to the DEAD box helicase family
ABW99_RS04785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABW99_RS04790	COG1054	Belongs to the UPF0176 family
ABW99_RS04805	COG0463	Glycosyl transferase, family 2
ABW99_RS04805	COG1216	Glycosyl transferase, family 2
ABW99_RS04830	COG1530	ribonuclease E activity
ABW99_RS04835	COG0424	maF-like protein
ABW99_RS04840	COG0584	glycerophosphoryl diester phosphodiesterase
ABW99_RS04850	COG0395	ABC-type sugar transport system, permease component
ABW99_RS04855	COG1175	transmembrane transport
ABW99_RS04860	COG1653	transport
ABW99_RS04865	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABW99_RS04870	COG0799	negative regulation of ribosome biogenesis
ABW99_RS04875	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ABW99_RS04880	COG0408	coproporphyrinogen oxidase activity
ABW99_RS04900	COG0151	Belongs to the GarS family
ABW99_RS04905	COG0217	transcriptional regulatory protein
ABW99_RS04910	COG1620	l-lactate permease
ABW99_RS04915	COG0697	spore germination
ABW99_RS04940	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ABW99_RS04945	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS04955	COG0583	DNA-binding transcription factor activity
ABW99_RS04960	COG3284	Transcriptional regulator
ABW99_RS04965	COG0583	DNA-binding transcription factor activity
ABW99_RS04970	COG3328	transposase activity
ABW99_RS04975	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS04985	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABW99_RS04990	COG0183	Belongs to the thiolase family
ABW99_RS04995	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS05010	COG0436	Aminotransferase
ABW99_RS05035	COG2721	sulfolactate sulfo-lyase activity
ABW99_RS05045	COG0667	Aldo Keto reductase
ABW99_RS05060	COG4608	Belongs to the ABC transporter superfamily
ABW99_RS05065	COG0444	Belongs to the ABC transporter superfamily
ABW99_RS05070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABW99_RS05075	COG0747	negative chemotaxis
ABW99_RS05080	COG1473	amidohydrolase
ABW99_RS05085	COG0601	transmembrane transport
ABW99_RS05135	COG2169	Transcriptional regulator
ABW99_RS05135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABW99_RS05150	COG2814	Major facilitator Superfamily
ABW99_RS05155	COG2860	membrane
ABW99_RS05175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABW99_RS05180	COG0456	acetyltransferase
ABW99_RS05185	COG0456	acetyltransferase
ABW99_RS05185	COG1846	Transcriptional regulator
ABW99_RS05205	COG0667	Aldo Keto reductase
ABW99_RS05220	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABW99_RS05225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS05230	COG1280	lysine exporter protein (LysE YggA)
ABW99_RS05235	COG0604	alcohol dehydrogenase
ABW99_RS05235	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS05235	COG3321	synthase
ABW99_RS05240	COG0583	DNA-binding transcription factor activity
ABW99_RS05275	COG0789	Transcriptional regulator
ABW99_RS05295	COG2814	Major facilitator Superfamily
ABW99_RS05295	COG0477	Major facilitator Superfamily
ABW99_RS05300	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ABW99_RS05320	COG0583	DNA-binding transcription factor activity
ABW99_RS05325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABW99_RS05345	COG0640	Transcriptional regulator
ABW99_RS05360	COG1959	2 iron, 2 sulfur cluster binding
ABW99_RS05370	COG2151	metal-sulfur cluster biosynthetic enzyme
ABW99_RS05390	COG1686	Belongs to the peptidase S11 family
ABW99_RS05400	COG2084	Dehydrogenase
ABW99_RS05420	COG0583	DNA-binding transcription factor activity
ABW99_RS05425	COG0730	response to heat
ABW99_RS05430	COG0175	sulfate reduction
ABW99_RS05440	COG2895	sulfate adenylyltransferase (ATP) activity
ABW99_RS05445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABW99_RS05445	COG1648	precorrin-2 dehydrogenase activity
ABW99_RS05460	COG0795	lipopolysaccharide-transporting ATPase activity
ABW99_RS05465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABW99_RS05485	COG0583	DNA-binding transcription factor activity
ABW99_RS05490	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ABW99_RS05495	COG1802	Transcriptional regulator
ABW99_RS05520	COG0410	ABC transporter
ABW99_RS05535	COG1228	amidohydrolase
ABW99_RS05540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABW99_RS05555	COG1024	Enoyl-CoA hydratase
ABW99_RS05560	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS05595	COG4206	TonB-dependent receptor
ABW99_RS05600	COG4139	cobalamin transport
ABW99_RS05605	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ABW99_RS05610	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ABW99_RS05615	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ABW99_RS05625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABW99_RS05640	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABW99_RS05645	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABW99_RS05650	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ABW99_RS05660	COG0729	surface antigen
ABW99_RS05675	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABW99_RS05675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABW99_RS05680	COG2885	chlorophyll binding
ABW99_RS05680	COG3047	cAMP biosynthetic process
ABW99_RS05685	COG0489	protein tyrosine kinase activity
ABW99_RS05690	COG0717	Belongs to the dCTP deaminase family
ABW99_RS05720	COG1595	DNA-templated transcription, initiation
ABW99_RS05730	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ABW99_RS05735	COG0181	hydroxymethylbilane synthase activity
ABW99_RS05750	COG2271	Major facilitator Superfamily
ABW99_RS05765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ABW99_RS05770	COG0247	lactate metabolic process
ABW99_RS05775	COG0277	FAD linked oxidase domain protein
ABW99_RS05780	COG0277	FAD linked oxidase domain protein
ABW99_RS05800	COG0347	Belongs to the P(II) protein family
ABW99_RS05805	COG2840	Smr protein MutS2
ABW99_RS05810	COG0492	ferredoxin-NADP+ reductase activity
ABW99_RS05815	COG1674	ftsk spoiiie
ABW99_RS05820	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ABW99_RS05825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABW99_RS05830	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABW99_RS05840	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABW99_RS05855	COG0642	Histidine kinase
ABW99_RS05890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS05910	COG1850	ribulose-bisphosphate carboxylase activity
ABW99_RS05920	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABW99_RS05930	COG1609	Transcriptional regulator
ABW99_RS05940	COG3842	ATPase activity
ABW99_RS05960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ABW99_RS05965	COG0583	DNA-binding transcription factor activity
ABW99_RS05970	COG1929	Belongs to the glycerate kinase type-1 family
ABW99_RS05980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ABW99_RS05990	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS06005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS06010	COG3938	Belongs to the proline racemase family
ABW99_RS06015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABW99_RS06030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABW99_RS06035	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABW99_RS06045	COG1561	YicC-like family, N-terminal region
ABW99_RS06060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABW99_RS06070	COG1741	Belongs to the pirin family
ABW99_RS06090	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ABW99_RS06095	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ABW99_RS06100	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ABW99_RS06105	COG2205	protein histidine kinase activity
ABW99_RS06110	COG0745	RESPONSE REGULATOR receiver
ABW99_RS06125	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ABW99_RS06135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABW99_RS06155	COG0438	transferase activity, transferring glycosyl groups
ABW99_RS06185	COG0028	Belongs to the TPP enzyme family
ABW99_RS06190	COG0440	acetolactate synthase activity
ABW99_RS06200	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABW99_RS06205	COG0688	phosphatidylethanolamine metabolic process
ABW99_RS06210	COG1183	phosphatidylcholine synthase activity
ABW99_RS06215	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABW99_RS06260	COG0589	response to stress
ABW99_RS06280	COG0415	Belongs to the DNA photolyase family
ABW99_RS06285	COG0300	oxidoreductase activity
ABW99_RS06305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ABW99_RS06315	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ABW99_RS06320	COG1309	transcriptional regulator
ABW99_RS06340	COG1846	Transcriptional regulator
ABW99_RS06345	COG1764	response to oxidative stress
ABW99_RS06370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABW99_RS06380	COG1595	DNA-templated transcription, initiation
ABW99_RS06385	COG0006	proline dipeptidase activity
ABW99_RS06390	COG0308	aminopeptidase N
ABW99_RS06400	COG1522	sequence-specific DNA binding
ABW99_RS06425	COG4178	(ABC) transporter
ABW99_RS06430	COG0312	modulator of DNA gyrase
ABW99_RS06435	COG0312	modulator of DNA gyrase
ABW99_RS06450	COG0492	ferredoxin-NADP+ reductase activity
ABW99_RS06475	COG0667	Aldo Keto reductase
ABW99_RS06480	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS06520	COG1024	Enoyl-CoA hydratase
ABW99_RS06530	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS06535	COG1562	ergosterol biosynthetic process
ABW99_RS06540	COG1657	PFAM Prenyltransferase squalene oxidase
ABW99_RS06555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABW99_RS06560	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABW99_RS06590	COG2153	protein acetylation
ABW99_RS06595	COG0488	(ABC) transporter
ABW99_RS06620	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ABW99_RS06630	COG0583	DNA-binding transcription factor activity
ABW99_RS06635	COG2814	Major facilitator Superfamily
ABW99_RS06655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABW99_RS06660	COG0697	spore germination
ABW99_RS06675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABW99_RS06685	COG3161	chorismate lyase activity
ABW99_RS06715	COG3135	benzoate transporter
ABW99_RS06750	COG0778	Nitroreductase
ABW99_RS06755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABW99_RS06760	COG2878	Part of a membrane complex involved in electron transport
ABW99_RS06765	COG1309	transcriptional regulator
ABW99_RS06780	COG0556	nucleotide-excision repair
ABW99_RS06790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABW99_RS06805	COG1104	cysteine desulfurase activity
ABW99_RS06810	COG0822	iron-sulfur transferase activity
ABW99_RS06815	COG0316	Belongs to the HesB IscA family
ABW99_RS06825	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ABW99_RS06840	COG2975	iron-sulfur cluster assembly
ABW99_RS06865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABW99_RS06885	COG0084	hydrolase, TatD family'
ABW99_RS06890	COG0658	competence protein
ABW99_RS06890	COG2333	competence protein COMEC
ABW99_RS06895	COG2267	carboxylic ester hydrolase activity
ABW99_RS06900	COG0504	CTP synthase activity
ABW99_RS06905	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ABW99_RS06910	COG0148	phosphopyruvate hydratase activity
ABW99_RS06915	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ABW99_RS06925	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ABW99_RS06935	COG2833	Protein of unknown function (DUF455)
ABW99_RS06945	COG0613	PHP domain protein
ABW99_RS06950	COG0009	L-threonylcarbamoyladenylate synthase
ABW99_RS06955	COG1994	Peptidase M50
ABW99_RS06960	COG0180	Tryptophanyl-tRNA synthetase
ABW99_RS06970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABW99_RS06975	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ABW99_RS06980	COG0321	lipoyl(octanoyl) transferase activity
ABW99_RS06980	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ABW99_RS06995	COG2850	peptidyl-arginine hydroxylation
ABW99_RS07005	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABW99_RS07015	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABW99_RS07020	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABW99_RS07025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ABW99_RS07045	COG0776	regulation of translation
ABW99_RS07060	COG0105	UTP biosynthetic process
ABW99_RS07080	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABW99_RS07085	COG0124	histidyl-tRNA synthetase
ABW99_RS07090	COG2976	Protein conserved in bacteria
ABW99_RS07095	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABW99_RS07105	COG1923	regulation of RNA biosynthetic process
ABW99_RS07110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ABW99_RS07115	COG0330	HflC and HflK could
ABW99_RS07120	COG0330	HflC and HflK could
ABW99_RS07130	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABW99_RS07140	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ABW99_RS07150	COG1959	2 iron, 2 sulfur cluster binding
ABW99_RS07160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABW99_RS07165	COG4566	intracellular signal transduction
ABW99_RS07175	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ABW99_RS07180	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABW99_RS07190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABW99_RS07205	COG1686	Belongs to the peptidase S11 family
ABW99_RS07210	COG1414	Transcriptional regulator
ABW99_RS07225	COG0765	amino acid transport
ABW99_RS07230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS07235	COG0167	dihydroorotate dehydrogenase activity
ABW99_RS07240	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ABW99_RS07260	COG0583	DNA-binding transcription factor activity
ABW99_RS07285	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ABW99_RS07305	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABW99_RS07310	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ABW99_RS07315	COG0567	Dehydrogenase, E1 component
ABW99_RS07320	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABW99_RS07325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABW99_RS07330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ABW99_RS07345	COG5642	Protein of unknown function (DUF2384)
ABW99_RS07350	COG5654	RES domain protein
ABW99_RS07370	COG1846	Transcriptional regulator
ABW99_RS07390	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ABW99_RS07405	COG4964	Belongs to the GSP D family
ABW99_RS07455	COG3158	transport of potassium into the cell
ABW99_RS07460	COG1297	OPT oligopeptide transporter protein
ABW99_RS07465	COG0477	Major facilitator Superfamily
ABW99_RS07475	COG2183	response to ionizing radiation
ABW99_RS07490	COG1199	ATP-dependent helicase activity
ABW99_RS07500	COG0564	pseudouridine synthase activity
ABW99_RS07510	COG3243	poly(R)-hydroxyalkanoic acid synthase
ABW99_RS07515	COG0183	Belongs to the thiolase family
ABW99_RS07520	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS07530	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABW99_RS07540	COG0183	Belongs to the thiolase family
ABW99_RS07570	COG0288	reversible hydration of carbon dioxide
ABW99_RS07575	COG0626	cystathionine gamma-synthase activity
ABW99_RS07580	COG0560	Phosphoserine phosphatase
ABW99_RS07615	COG0725	ABC transporter, periplasmic molybdate-binding protein
ABW99_RS07625	COG3842	ATPase activity
ABW99_RS07635	COG0625	glutathione transferase activity
ABW99_RS07650	COG3038	cytochrome b561
ABW99_RS07670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ABW99_RS07700	COG1686	Belongs to the peptidase S11 family
ABW99_RS07720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS07755	COG3038	cytochrome b561
ABW99_RS07775	COG3384	dioxygenase
ABW99_RS07785	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS07790	COG1902	pentaerythritol trinitrate reductase activity
ABW99_RS07795	COG0183	Belongs to the thiolase family
ABW99_RS07825	COG0840	transmembrane signaling receptor activity
ABW99_RS07830	COG5001	Diguanylate cyclase
ABW99_RS07835	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABW99_RS07840	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ABW99_RS07855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABW99_RS07875	COG1522	sequence-specific DNA binding
ABW99_RS07890	COG2235	arginine
ABW99_RS07895	COG1982	Orn Lys Arg decarboxylase major
ABW99_RS07900	COG0531	amino acid
ABW99_RS07905	COG0477	Major facilitator Superfamily
ABW99_RS07910	COG2814	Major facilitator Superfamily
ABW99_RS07915	COG1902	pentaerythritol trinitrate reductase activity
ABW99_RS07950	COG2375	cellular response to nickel ion
ABW99_RS07965	COG1802	Transcriptional regulator
ABW99_RS07970	COG2271	Major facilitator Superfamily
ABW99_RS07980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ABW99_RS08005	COG2207	Transcriptional regulator
ABW99_RS08010	COG0583	DNA-binding transcription factor activity
ABW99_RS08015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS08020	COG1024	Enoyl-CoA hydratase
ABW99_RS08030	COG0477	Major facilitator Superfamily
ABW99_RS08035	COG0583	DNA-binding transcription factor activity
ABW99_RS08055	COG0583	DNA-binding transcription factor activity
ABW99_RS08070	COG2814	Major facilitator Superfamily
ABW99_RS08095	COG0583	DNA-binding transcription factor activity
ABW99_RS08105	COG0697	spore germination
ABW99_RS08110	COG0778	Nitroreductase
ABW99_RS08115	COG0583	DNA-binding transcription factor activity
ABW99_RS08120	COG1819	glycosyl
ABW99_RS08135	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABW99_RS08140	COG2188	Transcriptional regulator
ABW99_RS08145	COG2814	Major facilitator Superfamily
ABW99_RS08165	COG0583	DNA-binding transcription factor activity
ABW99_RS08210	COG0346	lactoylglutathione lyase activity
ABW99_RS08215	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABW99_RS08220	COG3261	NADH dehydrogenase
ABW99_RS08220	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ABW99_RS08225	COG0651	ATP synthesis coupled electron transport
ABW99_RS08235	COG0650	Formate hydrogenlyase subunit 4
ABW99_RS08240	COG0651	ATP synthesis coupled electron transport
ABW99_RS08255	COG0129	dihydroxy-acid dehydratase activity
ABW99_RS08265	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ABW99_RS08285	COG0523	cobalamin synthesis protein
ABW99_RS08320	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABW99_RS08325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABW99_RS08350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABW99_RS08380	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ABW99_RS08400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABW99_RS08405	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ABW99_RS08420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABW99_RS08430	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ABW99_RS08440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ABW99_RS08445	COG4988	ABC transporter
ABW99_RS08455	COG1294	oxidase, subunit
ABW99_RS08460	COG1271	oxidase subunit
ABW99_RS08475	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS08485	COG0667	Aldo Keto reductase
ABW99_RS08495	COG0456	acetyltransferase
ABW99_RS08525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS08530	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABW99_RS08560	COG3344	reverse transcriptase
ABW99_RS08570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABW99_RS08575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABW99_RS08605	COG3300	MHYT domain
ABW99_RS08605	COG5001	Diguanylate cyclase
ABW99_RS08620	COG1522	sequence-specific DNA binding
ABW99_RS08630	COG0596	Alpha beta hydrolase
ABW99_RS08640	COG0583	DNA-binding transcription factor activity
ABW99_RS08645	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABW99_RS08665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABW99_RS08680	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ABW99_RS08685	COG0477	Major facilitator Superfamily
ABW99_RS08695	COG1595	DNA-templated transcription, initiation
ABW99_RS08710	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ABW99_RS08720	COG4221	oxidoreductase activity
ABW99_RS08730	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ABW99_RS08735	COG4941	Belongs to the sigma-70 factor family
ABW99_RS08740	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ABW99_RS08745	COG3795	YCII-related domain
ABW99_RS08755	COG0640	Transcriptional regulator
ABW99_RS08810	COG1802	Transcriptional regulator
ABW99_RS08830	COG4572	Cation transport regulator
ABW99_RS08840	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ABW99_RS08845	COG3842	ATPase activity
ABW99_RS08850	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABW99_RS08855	COG1177	transmembrane transport
ABW99_RS08865	COG0456	acetyltransferase
ABW99_RS08865	COG1214	PFAM Peptidase M22, glycoprotease
ABW99_RS08875	COG0765	amino acid transport
ABW99_RS08880	COG1126	abc transporter atp-binding protein
ABW99_RS08890	COG0477	Major facilitator Superfamily
ABW99_RS08895	COG0154	amidase activity
ABW99_RS08910	COG1914	H( )-stimulated, divalent metal cation uptake system
ABW99_RS08955	COG0583	DNA-binding transcription factor activity
ABW99_RS08980	COG0589	response to stress
ABW99_RS08985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABW99_RS09020	COG2301	Belongs to the HpcH HpaI aldolase family
ABW99_RS09030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS09035	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS09045	COG2271	Major facilitator Superfamily
ABW99_RS09060	COG0671	phosphoesterase, PA-phosphatase related
ABW99_RS09065	COG0642	Histidine kinase
ABW99_RS09075	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABW99_RS09105	COG2031	fatty acid transporter
ABW99_RS09120	COG0625	glutathione transferase activity
ABW99_RS09125	COG0024	Methionine aminopeptidase
ABW99_RS09140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABW99_RS09160	COG0667	Aldo Keto reductase
ABW99_RS09180	COG1309	transcriptional regulator
ABW99_RS09190	COG1294	oxidase, subunit
ABW99_RS09195	COG1271	oxidase subunit
ABW99_RS09205	COG3550	peptidyl-serine autophosphorylation
ABW99_RS09215	COG5001	Diguanylate cyclase
ABW99_RS09215	COG5002	protein histidine kinase activity
ABW99_RS09215	COG3447	MASE1 domain protein
ABW99_RS09250	COG0840	transmembrane signaling receptor activity
ABW99_RS09290	COG1309	transcriptional regulator
ABW99_RS09295	COG1979	alcohol dehydrogenase
ABW99_RS09320	COG0583	DNA-binding transcription factor activity
ABW99_RS09330	COG3795	YCII-related domain
ABW99_RS09360	COG3344	reverse transcriptase
ABW99_RS09365	COG0583	DNA-binding transcription factor activity
ABW99_RS09375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABW99_RS09395	COG0477	Major facilitator Superfamily
ABW99_RS09405	COG0583	DNA-binding transcription factor activity
ABW99_RS09420	COG0567	Dehydrogenase, E1 component
ABW99_RS09445	COG0123	including yeast histone deacetylase and acetoin utilization protein
ABW99_RS09470	COG1126	abc transporter atp-binding protein
ABW99_RS09475	COG0765	amino acid transport
ABW99_RS09485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS09510	COG2855	membrane
ABW99_RS09530	COG0477	Major facilitator Superfamily
ABW99_RS09550	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ABW99_RS09560	COG0655	NAD(P)H dehydrogenase (quinone) activity
ABW99_RS09615	COG4964	Belongs to the GSP D family
ABW99_RS09640	COG1414	Transcriptional regulator
ABW99_RS09665	COG1024	Enoyl-CoA hydratase
ABW99_RS09675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABW99_RS09680	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS09705	COG2885	chlorophyll binding
ABW99_RS09715	COG0477	Major facilitator Superfamily
ABW99_RS09720	COG1414	Transcriptional regulator
ABW99_RS09725	COG3246	L-lysine catabolic process to acetate
ABW99_RS09730	COG0511	ligase activity, forming carbon-carbon bonds
ABW99_RS09735	COG0439	Biotin carboxylase
ABW99_RS09750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS09755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABW99_RS09755	COG1116	anion transmembrane transporter activity
ABW99_RS09760	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS09780	COG5002	protein histidine kinase activity
ABW99_RS09780	COG3447	MASE1 domain protein
ABW99_RS09780	COG5001	Diguanylate cyclase
ABW99_RS09785	COG1024	Enoyl-CoA hydratase
ABW99_RS09795	COG3842	ATPase activity
ABW99_RS09800	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABW99_RS09805	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS09815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ABW99_RS09825	COG1802	Transcriptional regulator
ABW99_RS09835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS09845	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ABW99_RS09850	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ABW99_RS09870	COG0583	DNA-binding transcription factor activity
ABW99_RS09885	COG0583	DNA-binding transcription factor activity
ABW99_RS09895	COG0469	pyruvate kinase activity
ABW99_RS09905	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABW99_RS09910	COG0450	alkyl hydroperoxide reductase
ABW99_RS09930	COG1562	ergosterol biosynthetic process
ABW99_RS09945	COG0850	regulation of cytokinetic process
ABW99_RS09950	COG2894	cell division
ABW99_RS09955	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ABW99_RS09960	COG2267	carboxylic ester hydrolase activity
ABW99_RS09975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS09980	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABW99_RS09985	COG0740	serine-type endopeptidase activity
ABW99_RS09995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABW99_RS10000	COG0776	regulation of translation
ABW99_RS10015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABW99_RS10025	COG4181	ATPase activity
ABW99_RS10030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABW99_RS10030	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ABW99_RS10035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS10040	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABW99_RS10040	COG0047	phosphoribosylformylglycinamidine synthase activity
ABW99_RS10045	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABW99_RS10050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABW99_RS10060	COG2917	probably involved in intracellular septation
ABW99_RS10065	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABW99_RS10070	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ABW99_RS10075	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS10090	COG1335	isochorismatase
ABW99_RS10095	COG0183	Belongs to the thiolase family
ABW99_RS10110	COG2130	NADP-dependent
ABW99_RS10115	COG1454	alcohol dehydrogenase
ABW99_RS10120	COG0657	acetylesterase activity
ABW99_RS10125	COG1592	Rubrerythrin
ABW99_RS10130	COG0247	lactate metabolic process
ABW99_RS10150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABW99_RS10155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABW99_RS10215	COG0354	folic acid binding
ABW99_RS10220	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABW99_RS10225	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABW99_RS10235	COG1247	-acetyltransferase
ABW99_RS10240	COG0084	hydrolase, TatD family'
ABW99_RS10250	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ABW99_RS10265	COG1254	Belongs to the acylphosphatase family
ABW99_RS10285	COG1522	sequence-specific DNA binding
ABW99_RS10310	COG4638	Rieske (2fe-2S)
ABW99_RS10340	COG0783	Belongs to the Dps family
ABW99_RS10345	COG1042	CoA-binding domain protein
ABW99_RS10345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABW99_RS10345	COG0045	succinate-CoA ligase (ADP-forming) activity
ABW99_RS10350	COG0598	Magnesium transport protein CorA
ABW99_RS10355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABW99_RS10370	COG0735	belongs to the Fur family
ABW99_RS10375	COG3023	N-Acetylmuramoyl-L-alanine amidase
ABW99_RS10395	COG0583	DNA-binding transcription factor activity
ABW99_RS10400	COG0596	Alpha beta hydrolase
ABW99_RS10405	COG0038	chloride channel
ABW99_RS10410	COG3302	dmso reductase anchor subunit
ABW99_RS10415	COG0437	4 iron, 4 sulfur cluster binding
ABW99_RS10420	COG0243	molybdopterin cofactor binding
ABW99_RS10430	COG0277	FAD linked oxidase domain protein
ABW99_RS10440	COG0583	DNA-binding transcription factor activity
ABW99_RS10455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS10460	COG0765	amino acid transport
ABW99_RS10465	COG0765	amino acid transport
ABW99_RS10480	COG2188	Transcriptional regulator
ABW99_RS10485	COG2986	histidine ammonia-lyase
ABW99_RS10490	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ABW99_RS10500	COG1228	amidohydrolase
ABW99_RS10535	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABW99_RS10545	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS10550	COG3384	dioxygenase
ABW99_RS10560	COG3971	2-oxopent-4-enoate hydratase activity
ABW99_RS10570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABW99_RS10575	COG0730	response to heat
ABW99_RS10580	COG3258	Cytochrome c
ABW99_RS10585	COG2863	cytochrome
ABW99_RS10595	COG3453	Protein conserved in bacteria
ABW99_RS10595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABW99_RS10600	COG3459	Glycosyltransferase 36 associated
ABW99_RS10630	COG1215	transferase activity, transferring glycosyl groups
ABW99_RS10645	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ABW99_RS10710	COG5487	UPF0391 membrane protein
ABW99_RS10745	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ABW99_RS10775	COG0166	Belongs to the GPI family
ABW99_RS10780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABW99_RS10795	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ABW99_RS10835	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABW99_RS10840	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ABW99_RS10845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABW99_RS10845	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABW99_RS10855	COG0356	it plays a direct role in the translocation of protons across the membrane
ABW99_RS10870	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABW99_RS10875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABW99_RS10880	COG3243	poly(R)-hydroxyalkanoic acid synthase
ABW99_RS10890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABW99_RS10915	COG0589	response to stress
ABW99_RS10925	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ABW99_RS10930	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS10985	COG0640	Transcriptional regulator
ABW99_RS11005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABW99_RS11015	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABW99_RS11020	COG2326	polyphosphate kinase activity
ABW99_RS11030	COG1584	GPR1 FUN34 yaaH family protein
ABW99_RS11035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABW99_RS11040	COG2132	Multicopper oxidase
ABW99_RS11050	COG0463	Glycosyl transferase, family 2
ABW99_RS11070	COG1215	transferase activity, transferring glycosyl groups
ABW99_RS11075	COG1984	allophanate hydrolase subunit 2
ABW99_RS11080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ABW99_RS11095	COG0583	DNA-binding transcription factor activity
ABW99_RS11105	COG3842	ATPase activity
ABW99_RS11110	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABW99_RS11115	COG1177	transmembrane transport
ABW99_RS11145	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABW99_RS11170	COG1566	PFAM secretion protein HlyD family protein
ABW99_RS11185	COG0811	peptide transport
ABW99_RS11190	COG0848	biopolymer transport protein
ABW99_RS11220	COG1538	Outer membrane efflux protein
ABW99_RS11225	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABW99_RS11270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ABW99_RS11275	COG0477	Major facilitator Superfamily
ABW99_RS11280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABW99_RS11295	COG0438	transferase activity, transferring glycosyl groups
ABW99_RS11325	COG0739	heme binding
ABW99_RS11335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABW99_RS11340	COG1228	amidohydrolase
ABW99_RS11345	COG0523	cobalamin synthesis protein
ABW99_RS11350	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ABW99_RS11390	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ABW99_RS11415	COG0583	DNA-binding transcription factor activity
ABW99_RS11420	COG3618	amidohydrolase
ABW99_RS11430	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ABW99_RS11440	COG0523	cobalamin synthesis protein
ABW99_RS11445	COG2233	PERMEase
ABW99_RS11455	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS11480	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABW99_RS11485	COG1172	Belongs to the binding-protein-dependent transport system permease family
ABW99_RS11490	COG4191	Histidine kinase
ABW99_RS11505	COG1802	Transcriptional regulator
ABW99_RS11515	COG2020	methyltransferase activity
ABW99_RS11520	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ABW99_RS11550	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ABW99_RS11560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABW99_RS11565	COG3394	polysaccharide catabolic process
ABW99_RS11580	COG2223	nitrite transmembrane transporter activity
ABW99_RS11590	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ABW99_RS11595	COG3383	formate dehydrogenase (NAD+) activity
ABW99_RS11670	COG3842	ATPase activity
ABW99_RS11680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABW99_RS11695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ABW99_RS11695	COG2010	Cytochrome c
ABW99_RS11705	COG0583	DNA-binding transcription factor activity
ABW99_RS11715	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABW99_RS11720	COG3842	ATPase activity
ABW99_RS11725	COG1177	transmembrane transport
ABW99_RS11730	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ABW99_RS11740	COG1609	Transcriptional regulator
ABW99_RS11760	COG3706	GGDEF domain
ABW99_RS11780	COG0488	(ABC) transporter
ABW99_RS11795	COG0583	DNA-binding transcription factor activity
ABW99_RS11805	COG2233	PERMEase
ABW99_RS11850	COG1113	amino acid transport
ABW99_RS11860	COG4266	Belongs to the allantoicase family
ABW99_RS11875	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS11885	COG1953	Uracil, thiamine, allantoin
ABW99_RS11890	COG2186	Transcriptional regulator
ABW99_RS11895	COG0840	transmembrane signaling receptor activity
ABW99_RS11900	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABW99_RS11920	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS11925	COG0798	PFAM Bile acid sodium symporter
ABW99_RS11930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABW99_RS11955	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS11985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABW99_RS11985	COG0519	Catalyzes the synthesis of GMP from XMP
ABW99_RS12005	COG2914	Belongs to the UPF0125 (RnfH) family
ABW99_RS12010	COG2867	negative regulation of translational initiation
ABW99_RS12015	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABW99_RS12020	COG0330	HflC and HflK could
ABW99_RS12035	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ABW99_RS12040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABW99_RS12050	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABW99_RS12055	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABW99_RS12065	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABW99_RS12070	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ABW99_RS12080	COG0750	zinc metalloprotease
ABW99_RS12095	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABW99_RS12105	COG0528	UMP kinase activity
ABW99_RS12110	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ABW99_RS12115	COG0052	Belongs to the universal ribosomal protein uS2 family
ABW99_RS12120	COG0024	Methionine aminopeptidase
ABW99_RS12130	COG1187	pseudouridine synthase activity
ABW99_RS12135	COG0242	peptide deformylase activity
ABW99_RS12140	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABW99_RS12165	COG2171	N-acyltransferase activity
ABW99_RS12170	COG1393	Belongs to the ArsC family
ABW99_RS12180	COG2890	protein-(glutamine-N5) methyltransferase activity
ABW99_RS12185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABW99_RS12190	COG0488	(ABC) transporter
ABW99_RS12200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABW99_RS12205	COG0477	Major facilitator Superfamily
ABW99_RS12210	COG0351	phosphomethylpyrimidine kinase
ABW99_RS12220	COG1573	uracil-dna glycosylase
ABW99_RS12230	COG1214	PFAM Peptidase M22, glycoprotease
ABW99_RS12235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS12240	COG0765	amino acid transport
ABW99_RS12245	COG0765	amino acid transport
ABW99_RS12250	COG1126	abc transporter atp-binding protein
ABW99_RS12255	COG5285	phytanoyl-CoA dioxygenase
ABW99_RS12260	COG0662	Cupin 2, conserved barrel domain protein
ABW99_RS12280	COG0513	Belongs to the DEAD box helicase family
ABW99_RS12285	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ABW99_RS12295	COG0583	DNA-binding transcription factor activity
ABW99_RS12300	COG0589	response to stress
ABW99_RS12305	COG2224	Isocitrate lyase
ABW99_RS12310	COG0697	spore germination
ABW99_RS12320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABW99_RS12325	COG0583	DNA-binding transcription factor activity
ABW99_RS12350	COG0542	response to heat
ABW99_RS12355	COG2346	COG2346, Truncated hemoglobins
ABW99_RS12360	COG0314	molybdopterin synthase activity
ABW99_RS12370	COG0303	'Molybdopterin
ABW99_RS12375	COG1573	uracil-dna glycosylase
ABW99_RS12390	COG0436	Aminotransferase
ABW99_RS12405	COG2076	Multidrug Resistance protein
ABW99_RS12410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABW99_RS12415	COG0463	Glycosyl transferase, family 2
ABW99_RS12430	COG0726	polysaccharide deacetylase
ABW99_RS12435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABW99_RS12440	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ABW99_RS12445	COG0791	NLP P60 protein
ABW99_RS12455	COG0359	binds to the 23S rRNA
ABW99_RS12475	COG0583	DNA-binding transcription factor activity
ABW99_RS12480	COG3960	tartronate-semialdehyde synthase activity
ABW99_RS12485	COG3622	Belongs to the hyi family
ABW99_RS12490	COG2084	Dehydrogenase
ABW99_RS12500	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ABW99_RS12510	COG0252	asparaginase activity
ABW99_RS12515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABW99_RS12525	COG1024	Enoyl-CoA hydratase
ABW99_RS12530	COG1217	gtp-binding protein TYPA
ABW99_RS12545	COG1566	PFAM secretion protein HlyD family protein
ABW99_RS12550	COG2814	Major facilitator Superfamily
ABW99_RS12555	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABW99_RS12565	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABW99_RS12570	COG2251	uridine kinase activity
ABW99_RS12570	COG0195	Participates in both transcription termination and antitermination
ABW99_RS12575	COG0779	Required for maturation of 30S ribosomal subunits
ABW99_RS12580	COG1187	pseudouridine synthase activity
ABW99_RS12585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ABW99_RS12590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABW99_RS12595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABW99_RS12615	COG1643	Atp-dependent helicase
ABW99_RS12620	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ABW99_RS12620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABW99_RS12625	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ABW99_RS12635	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ABW99_RS12645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABW99_RS12650	COG0557	exoribonuclease II activity
ABW99_RS12665	COG0573	inorganic phosphate transmembrane transporter activity
ABW99_RS12690	COG0066	3-isopropylmalate dehydratase activity
ABW99_RS12695	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABW99_RS12700	COG0583	DNA-binding transcription factor activity
ABW99_RS12705	COG2814	Major facilitator Superfamily
ABW99_RS12730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABW99_RS12755	COG0473	3-isopropylmalate dehydrogenase activity
ABW99_RS12760	COG0583	DNA-binding transcription factor activity
ABW99_RS12765	COG2755	lipolytic protein G-D-S-L family
ABW99_RS12765	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ABW99_RS12775	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ABW99_RS12780	COG2818	Glycosylase
ABW99_RS12785	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABW99_RS12800	COG0745	RESPONSE REGULATOR receiver
ABW99_RS12805	COG0745	RESPONSE REGULATOR receiver
ABW99_RS12825	COG2204	response regulator
ABW99_RS12835	COG0174	glutamine synthetase
ABW99_RS12910	COG2186	Transcriptional regulator
ABW99_RS12915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABW99_RS12920	COG3395	kinase activity
ABW99_RS12925	COG0235	Class ii aldolase
ABW99_RS12930	COG0477	Major facilitator Superfamily
ABW99_RS12965	COG2814	Major facilitator Superfamily
ABW99_RS12995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABW99_RS13000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABW99_RS13060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABW99_RS13105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABW99_RS13110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABW99_RS13120	COG0183	Belongs to the thiolase family
ABW99_RS13125	COG1414	Transcriptional regulator
ABW99_RS13130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABW99_RS13165	COG0110	maltose O-acetyltransferase activity
ABW99_RS13195	COG1335	isochorismatase
ABW99_RS13240	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS13265	COG2207	Transcriptional regulator
ABW99_RS13275	COG0477	Major facilitator Superfamily
ABW99_RS13285	COG0235	Class ii aldolase
ABW99_RS13295	COG1064	alcohol dehydrogenase
ABW99_RS13300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS13305	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ABW99_RS13320	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS13325	COG0583	DNA-binding transcription factor activity
ABW99_RS13330	COG2814	Major facilitator Superfamily
ABW99_RS13335	COG0583	DNA-binding transcription factor activity
ABW99_RS13360	COG0583	DNA-binding transcription factor activity
ABW99_RS13375	COG1136	(ABC) transporter
ABW99_RS13375	COG0577	efflux transmembrane transporter activity
ABW99_RS13380	COG0577	efflux transmembrane transporter activity
ABW99_RS13380	COG1136	(ABC) transporter
ABW99_RS13410	COG0574	Belongs to the PEP-utilizing enzyme family
ABW99_RS13410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABW99_RS13420	COG0058	SHG alpha-glucan phosphorylase activity
ABW99_RS13450	COG0298	carbon dioxide binding
ABW99_RS13455	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ABW99_RS13480	COG0543	2 iron, 2 sulfur cluster binding
ABW99_RS13505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABW99_RS13510	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABW99_RS13525	COG0277	FAD linked oxidase domain protein
ABW99_RS13535	COG4977	sequence-specific DNA binding
ABW99_RS13570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ABW99_RS13575	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ABW99_RS13625	COG2204	response regulator
ABW99_RS13635	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABW99_RS13655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ABW99_RS13660	COG1840	ABC-type Fe3 transport system, periplasmic component
ABW99_RS13665	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABW99_RS13670	COG0791	NLP P60 protein
ABW99_RS13675	COG4172	Belongs to the ABC transporter superfamily
ABW99_RS13680	COG4239	(ABC) transporter, permease
ABW99_RS13685	COG4174	ABC transporter (Permease)
ABW99_RS13690	COG4166	transmembrane transport
ABW99_RS13710	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS13715	COG4689	acetoacetate decarboxylase
ABW99_RS13720	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS13745	COG0583	DNA-binding transcription factor activity
ABW99_RS13750	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ABW99_RS13765	COG0527	aspartate kinase activity
ABW99_RS13770	COG0037	tRNA processing
ABW99_RS13775	COG0825	malonyl-CoA metabolic process
ABW99_RS13780	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ABW99_RS13785	COG0215	cysteine-tRNA ligase activity
ABW99_RS13795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABW99_RS13800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABW99_RS13805	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABW99_RS13810	COG1045	serine acetyltransferase
ABW99_RS13820	COG0483	inositol monophosphate 1-phosphatase activity
ABW99_RS13830	COG4977	sequence-specific DNA binding
ABW99_RS13835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABW99_RS13860	COG0285	dihydrofolate synthase activity
ABW99_RS13865	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ABW99_RS13870	COG0159	tryptophan synthase activity
ABW99_RS13880	COG0133	tryptophan synthase activity
ABW99_RS13885	COG0135	phosphoribosylanthranilate isomerase activity
ABW99_RS13890	COG0101	tRNA pseudouridine synthase activity
ABW99_RS13900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABW99_RS13905	COG0473	3-isopropylmalate dehydrogenase activity
ABW99_RS13920	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABW99_RS13925	COG0372	Belongs to the citrate synthase family
ABW99_RS13930	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ABW99_RS13935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABW99_RS13940	COG1053	succinate dehydrogenase
ABW99_RS13945	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ABW99_RS13970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABW99_RS13980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABW99_RS14000	COG2866	Carboxypeptidase
ABW99_RS14005	COG3022	response to hydroperoxide
ABW99_RS14015	COG0436	Aminotransferase
ABW99_RS14020	COG0625	glutathione transferase activity
ABW99_RS14025	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABW99_RS14030	COG1024	Enoyl-CoA hydratase
ABW99_RS14040	COG0625	glutathione transferase activity
ABW99_RS14045	COG3422	double-strand break repair
ABW99_RS14070	COG1007	ATP synthesis coupled electron transport
ABW99_RS14085	COG0713	ATP synthesis coupled electron transport
ABW99_RS14095	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABW99_RS14100	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABW99_RS14105	COG1034	ATP synthesis coupled electron transport
ABW99_RS14120	COG0649	NAD binding
ABW99_RS14125	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABW99_RS14130	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABW99_RS14135	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABW99_RS14150	COG0149	triose-phosphate isomerase activity
ABW99_RS14160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABW99_RS14165	COG0251	oxidation-reduction process
ABW99_RS14190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABW99_RS14195	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS14205	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABW99_RS14210	COG0477	Major facilitator Superfamily
ABW99_RS14225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABW99_RS14235	COG1295	ribonuclease BN
ABW99_RS14250	COG0277	FAD linked oxidase domain protein
ABW99_RS14255	COG0254	rRNA binding
ABW99_RS14265	COG0534	Mate efflux family protein
ABW99_RS14300	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABW99_RS14310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABW99_RS14315	COG2081	HI0933 family
ABW99_RS14320	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABW99_RS14325	COG1469	GTP cyclohydrolase I activity
ABW99_RS14335	COG0142	geranyltranstransferase activity
ABW99_RS14340	COG1722	exodeoxyribonuclease VII activity
ABW99_RS14355	COG1252	NADH dehydrogenase
ABW99_RS14365	COG1611	Belongs to the LOG family
ABW99_RS14375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ABW99_RS14385	COG0210	DNA helicase
ABW99_RS14390	COG0525	valine-tRNA ligase activity
ABW99_RS14395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABW99_RS14400	COG0425	Belongs to the sulfur carrier protein TusA family
ABW99_RS14420	COG1942	4-Oxalocrotonate Tautomerase
ABW99_RS14425	COG0235	Class ii aldolase
ABW99_RS14430	COG0477	Major facilitator Superfamily
ABW99_RS14440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS14455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABW99_RS14515	COG4964	Belongs to the GSP D family
ABW99_RS14550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ABW99_RS14560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS14565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS14585	COG1178	ABC-type Fe3 transport system permease component
ABW99_RS14595	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ABW99_RS14630	COG0312	modulator of DNA gyrase
ABW99_RS14635	COG3028	Belongs to the UPF0307 family
ABW99_RS14640	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABW99_RS14660	COG2721	sulfolactate sulfo-lyase activity
ABW99_RS14665	COG2721	sulfolactate sulfo-lyase activity
ABW99_RS14670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABW99_RS14675	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABW99_RS14700	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABW99_RS14705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS14715	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ABW99_RS14720	COG1053	succinate dehydrogenase
ABW99_RS14735	COG0501	Belongs to the peptidase M48B family
ABW99_RS14740	COG1162	GTPase activity
ABW99_RS14745	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ABW99_RS14750	COG0494	nUDIX hydrolase
ABW99_RS14755	COG0335	large ribosomal subunit rRNA binding
ABW99_RS14760	COG0336	Belongs to the RNA methyltransferase TrmD family
ABW99_RS14765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABW99_RS14770	COG0228	four-way junction DNA binding
ABW99_RS14785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABW99_RS14800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS14805	COG0686	Belongs to the AlaDH PNT family
ABW99_RS14810	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS14835	COG1024	Enoyl-CoA hydratase
ABW99_RS14845	COG2951	lytic endotransglycosylase activity
ABW99_RS14860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABW99_RS14865	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ABW99_RS14875	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ABW99_RS14885	COG0776	regulation of translation
ABW99_RS14895	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ABW99_RS14900	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABW99_RS14905	COG0287	Prephenate dehydrogenase
ABW99_RS14910	COG1605	Chorismate mutase
ABW99_RS14910	COG0077	Prephenate dehydratase
ABW99_RS14915	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ABW99_RS14935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ABW99_RS14955	COG0697	spore germination
ABW99_RS14980	COG1522	sequence-specific DNA binding
ABW99_RS14990	COG5002	protein histidine kinase activity
ABW99_RS14990	COG5001	Diguanylate cyclase
ABW99_RS15020	COG1132	(ABC) transporter
ABW99_RS15025	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABW99_RS15025	COG0189	ligase activity
ABW99_RS15030	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABW99_RS15030	COG0189	ligase activity
ABW99_RS15055	COG0248	Ppx GppA phosphatase
ABW99_RS15060	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ABW99_RS15070	COG0745	RESPONSE REGULATOR receiver
ABW99_RS15085	COG0581	inorganic phosphate transmembrane transporter activity
ABW99_RS15090	COG0573	inorganic phosphate transmembrane transporter activity
ABW99_RS15095	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ABW99_RS15100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABW99_RS15105	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABW99_RS15110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABW99_RS15120	COG1534	Rna-binding protein
ABW99_RS15130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABW99_RS15135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABW99_RS15145	COG0505	Belongs to the CarA family
ABW99_RS15155	COG1301	dicarboxylic acid transport
ABW99_RS15160	COG4266	Belongs to the allantoicase family
ABW99_RS15185	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS15190	COG1024	Enoyl-CoA hydratase
ABW99_RS15195	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS15210	COG0741	lytic transglycosylase activity
ABW99_RS15210	COG1388	LysM domain
ABW99_RS15215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABW99_RS15225	COG0328	RNA-DNA hybrid ribonuclease activity
ABW99_RS15230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABW99_RS15240	COG1272	protein, Hemolysin III
ABW99_RS15260	COG2814	Major facilitator Superfamily
ABW99_RS15265	COG0010	Belongs to the arginase family
ABW99_RS15270	COG1126	abc transporter atp-binding protein
ABW99_RS15275	COG0765	amino acid transport
ABW99_RS15280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS15290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABW99_RS15310	COG2223	nitrite transmembrane transporter activity
ABW99_RS15315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABW99_RS15325	COG0243	molybdopterin cofactor binding
ABW99_RS15330	COG0583	DNA-binding transcription factor activity
ABW99_RS15335	COG0625	glutathione transferase activity
ABW99_RS15345	COG0587	DNA-directed DNA polymerase activity
ABW99_RS15365	COG2252	PERMEase
ABW99_RS15375	COG3021	interspecies interaction between organisms
ABW99_RS15380	COG2217	Heavy metal translocating P-type atpase
ABW99_RS15390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABW99_RS15390	COG4651	solute:proton antiporter activity
ABW99_RS15420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ABW99_RS15425	COG0402	S-adenosylhomocysteine deaminase activity
ABW99_RS15430	COG2119	membrane
ABW99_RS15440	COG0308	aminopeptidase N
ABW99_RS15450	COG0583	DNA-binding transcription factor activity
ABW99_RS15455	COG0540	Belongs to the ATCase OTCase family
ABW99_RS15475	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
ABW99_RS15480	COG0582	viral genome integration into host DNA
ABW99_RS15485	COG3093	addiction module antidote protein HigA
ABW99_RS15495	COG2860	membrane
ABW99_RS15510	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ABW99_RS15520	COG0243	molybdopterin cofactor binding
ABW99_RS15530	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABW99_RS15535	COG0657	acetylesterase activity
ABW99_RS15540	COG0402	S-adenosylhomocysteine deaminase activity
ABW99_RS15545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABW99_RS15560	COG0583	DNA-binding transcription factor activity
ABW99_RS15580	COG3321	synthase
ABW99_RS15580	COG0604	alcohol dehydrogenase
ABW99_RS15580	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS15585	COG0431	NADPH-dependent FMN reductase
ABW99_RS15600	COG2226	methyltransferase
ABW99_RS15615	COG1846	Transcriptional regulator
ABW99_RS15625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABW99_RS15635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABW99_RS15640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABW99_RS15645	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS15650	COG3958	Transketolase
ABW99_RS15655	COG3959	Transketolase, thiamine diphosphate binding domain
ABW99_RS15660	COG0583	DNA-binding transcription factor activity
ABW99_RS15665	COG2200	EAL domain
ABW99_RS15670	COG0678	peroxiredoxin activity
ABW99_RS15675	COG2188	Transcriptional regulator
ABW99_RS15680	COG2271	Major facilitator Superfamily
ABW99_RS15720	COG2814	Major facilitator Superfamily
ABW99_RS15735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABW99_RS15745	COG4521	taurine ABC transporter
ABW99_RS15750	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABW99_RS15755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS15760	COG2205	protein histidine kinase activity
ABW99_RS15765	COG0745	RESPONSE REGULATOR receiver
ABW99_RS15770	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABW99_RS15780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABW99_RS15805	COG1414	Transcriptional regulator
ABW99_RS15820	COG1113	amino acid transport
ABW99_RS15830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS15835	COG1414	Transcriptional regulator
ABW99_RS15845	COG0477	Major facilitator Superfamily
ABW99_RS15850	COG1414	Transcriptional regulator
ABW99_RS15870	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS15875	COG0318	PFAM AMP-dependent synthetase and ligase
ABW99_RS15880	COG2271	Major facilitator Superfamily
ABW99_RS15885	COG2084	Dehydrogenase
ABW99_RS15890	COG0824	Thioesterase
ABW99_RS15900	COG0848	biopolymer transport protein
ABW99_RS15910	COG0823	Involved in the tonB-independent uptake of proteins
ABW99_RS15915	COG2885	chlorophyll binding
ABW99_RS15920	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ABW99_RS15930	COG1968	undecaprenyl-diphosphatase activity
ABW99_RS15935	COG2252	PERMEase
ABW99_RS15945	COG3387	PFAM Glycoside hydrolase 15-related
ABW99_RS15950	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABW99_RS16005	COG4789	Type iii secretion
ABW99_RS16035	COG0076	glutamate decarboxylase activity
ABW99_RS16055	COG3033	Beta-eliminating lyase
ABW99_RS16060	COG5001	Diguanylate cyclase
ABW99_RS16060	COG3300	MHYT domain
ABW99_RS16070	COG2909	trisaccharide binding
ABW99_RS16095	COG2814	Major facilitator Superfamily
ABW99_RS16100	COG1522	sequence-specific DNA binding
ABW99_RS16105	COG2423	ornithine cyclodeaminase activity
ABW99_RS16130	COG1999	signal sequence binding
ABW99_RS16165	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABW99_RS16170	COG0438	transferase activity, transferring glycosyl groups
ABW99_RS16190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABW99_RS16215	COG0438	transferase activity, transferring glycosyl groups
ABW99_RS16230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABW99_RS16240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABW99_RS16245	COG2153	protein acetylation
ABW99_RS16250	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ABW99_RS16250	COG0662	Cupin 2, conserved barrel domain protein
ABW99_RS16255	COG2814	Major facilitator Superfamily
ABW99_RS16285	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ABW99_RS16290	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ABW99_RS16300	COG1473	amidohydrolase
ABW99_RS16305	COG0583	DNA-binding transcription factor activity
ABW99_RS16350	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS16360	COG0028	Belongs to the TPP enzyme family
ABW99_RS16365	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS16370	COG1414	Transcriptional regulator
ABW99_RS16385	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS16390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS16400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS16405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABW99_RS16415	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ABW99_RS16445	COG0322	excinuclease ABC activity
ABW99_RS16455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABW99_RS16460	COG2204	response regulator
ABW99_RS16470	COG0736	holo-[acyl-carrier-protein] synthase activity
ABW99_RS16475	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ABW99_RS16485	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABW99_RS16490	COG0571	ribonuclease III activity
ABW99_RS16495	COG0681	Belongs to the peptidase S26 family
ABW99_RS16510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABW99_RS16535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABW99_RS16540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABW99_RS16545	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS16555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABW99_RS16560	COG0416	fatty acid biosynthetic process
ABW99_RS16565	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ABW99_RS16570	COG1399	metal-binding, possibly nucleic acid-binding protein
ABW99_RS16575	COG0424	maF-like protein
ABW99_RS16585	COG0616	signal peptide processing
ABW99_RS16585	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ABW99_RS16595	COG0546	phosphoglycolate phosphatase activity
ABW99_RS16600	COG0564	pseudouridine synthase activity
ABW99_RS16605	COG1530	ribonuclease E activity
ABW99_RS16610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABW99_RS16615	COG0746	molybdenum cofactor guanylyltransferase activity
ABW99_RS16620	COG0303	'Molybdopterin
ABW99_RS16630	COG0456	acetyltransferase
ABW99_RS16635	COG1322	Protein conserved in bacteria
ABW99_RS16670	COG0579	oxidoreductase
ABW99_RS16680	COG3384	dioxygenase
ABW99_RS16690	COG1280	lysine exporter protein (LysE YggA)
ABW99_RS16700	COG1278	Cold shock
ABW99_RS16710	COG2943	transferase activity, transferring hexosyl groups
ABW99_RS16710	COG3416	Protein conserved in bacteria
ABW99_RS16715	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ABW99_RS16725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ABW99_RS16730	COG0251	oxidation-reduction process
ABW99_RS16755	COG0235	Class ii aldolase
ABW99_RS16760	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ABW99_RS16770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABW99_RS16775	COG1126	abc transporter atp-binding protein
ABW99_RS16780	COG0765	amino acid transport
ABW99_RS16785	COG0765	amino acid transport
ABW99_RS16815	COG0411	ABC transporter
ABW99_RS16845	COG0583	DNA-binding transcription factor activity
ABW99_RS16850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS16855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABW99_RS16860	COG0765	amino acid transport
ABW99_RS16865	COG1126	abc transporter atp-binding protein
ABW99_RS16890	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABW99_RS16900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ABW99_RS16905	COG0425	Belongs to the sulfur carrier protein TusA family
ABW99_RS16905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABW99_RS16920	COG0859	PFAM glycosyl transferase family 9
ABW99_RS16935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABW99_RS16945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABW99_RS16950	COG0438	transferase activity, transferring glycosyl groups
ABW99_RS17010	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABW99_RS17030	COG0540	Belongs to the ATCase OTCase family
ABW99_RS17035	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ABW99_RS17040	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABW99_RS17045	COG1678	Uncharacterized ACR, COG1678
ABW99_RS17055	COG1773	rubredoxin
ABW99_RS17060	COG0351	phosphomethylpyrimidine kinase
ABW99_RS17065	COG3307	-O-antigen
ABW99_RS17070	COG4969	Belongs to the N-Me-Phe pilin family
ABW99_RS17075	COG0861	Integral membrane protein TerC family
ABW99_RS17080	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ABW99_RS17085	COG0045	succinate-CoA ligase (ADP-forming) activity
ABW99_RS17095	COG2137	regulation of response to DNA damage stimulus
ABW99_RS17100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABW99_RS17115	COG0477	Major facilitator Superfamily
ABW99_RS17160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABW99_RS17170	COG1396	sequence-specific DNA binding
ABW99_RS17180	COG2271	Major facilitator Superfamily
ABW99_RS17185	COG1902	pentaerythritol trinitrate reductase activity
ABW99_RS17190	COG0668	transmembrane transport
ABW99_RS17220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABW99_RS17245	COG2719	SpoVR family
ABW99_RS17250	COG2718	Belongs to the UPF0229 family
ABW99_RS17255	COG2766	serine protein kinase
ABW99_RS17260	COG0803	Belongs to the bacterial solute-binding protein 9 family
ABW99_RS17265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABW99_RS17270	COG1702	phosphate starvation-inducible protein PhoH
ABW99_RS17275	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ABW99_RS17280	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ABW99_RS17290	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ABW99_RS17295	COG0752	glycyl-tRNA synthetase alpha subunit
ABW99_RS17300	COG0751	glycine-tRNA ligase activity
ABW99_RS17305	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ABW99_RS17310	COG0204	Acyl-transferase
ABW99_RS17320	COG0346	lactoylglutathione lyase activity
ABW99_RS17335	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABW99_RS17340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABW99_RS17345	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ABW99_RS17355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ABW99_RS17360	COG0006	proline dipeptidase activity
ABW99_RS17365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABW99_RS17370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABW99_RS17375	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ABW99_RS17380	COG0138	bifunctional purine biosynthesis protein purh
ABW99_RS17385	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABW99_RS17405	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ABW99_RS17410	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABW99_RS17415	COG0735	belongs to the Fur family
ABW99_RS17420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABW99_RS17425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABW99_RS17430	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ABW99_RS17440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABW99_RS17460	COG0281	malic enzyme
ABW99_RS17460	COG0280	phosphate acetyltransferase
ABW99_RS17470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABW99_RS17475	COG1058	Belongs to the CinA family
ABW99_RS17475	COG1546	Belongs to the CinA family
ABW99_RS17480	COG0284	orotidine-5'-phosphate decarboxylase activity
ABW99_RS17485	COG0668	transmembrane transport
ABW99_RS17490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABW99_RS17495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABW99_RS17505	COG0557	exoribonuclease II activity
ABW99_RS17515	COG1881	PFAM PEBP family protein
ABW99_RS17520	COG1490	D-aminoacyl-tRNA deacylase activity
ABW99_RS17535	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ABW99_RS17545	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABW99_RS17550	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABW99_RS17570	COG0418	dihydroorotase activity
ABW99_RS17575	COG0121	glutamine amidotransferase
ABW99_RS17580	COG1126	abc transporter atp-binding protein
ABW99_RS17585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABW99_RS17590	COG0583	DNA-binding transcription factor activity
ABW99_RS17595	COG5265	(ABC) transporter
ABW99_RS17610	COG0183	Belongs to the thiolase family
ABW99_RS17615	COG1024	Enoyl-CoA hydratase
ABW99_RS17615	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABW99_RS17620	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS17630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABW99_RS17635	COG0494	nUDIX hydrolase
ABW99_RS17660	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABW99_RS17675	COG2226	methyltransferase
ABW99_RS17690	COG0025	NhaP-type Na H and K H
ABW99_RS17710	COG1238	metal cluster binding
ABW99_RS17730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABW99_RS17750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABW99_RS17760	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS17765	COG3284	Transcriptional regulator
ABW99_RS17770	COG0596	Alpha beta hydrolase
ABW99_RS17780	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ABW99_RS17785	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
ABW99_RS17795	COG0535	radical SAM domain protein
ABW99_RS17820	COG1846	Transcriptional regulator
ABW99_RS17835	COG2902	Dehydrogenase
ABW99_RS17855	COG0656	L-ascorbic acid biosynthetic process
ABW99_RS17880	COG3344	reverse transcriptase
ABW99_RS17905	COG2233	PERMEase
ABW99_RS17935	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS17940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABW99_RS17955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS17960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS17965	COG1609	Transcriptional regulator
ABW99_RS17970	COG0629	single-stranded DNA binding
ABW99_RS17975	COG2814	Major facilitator Superfamily
ABW99_RS17995	COG1283	sodium-dependent phosphate transmembrane transporter activity
ABW99_RS18000	COG1012	belongs to the aldehyde dehydrogenase family
ABW99_RS18035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABW99_RS18060	COG0583	DNA-binding transcription factor activity
ABW99_RS18070	COG1280	lysine exporter protein (LysE YggA)
ABW99_RS18075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABW99_RS18105	COG1137	ATPase activity
ABW99_RS18110	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ABW99_RS18115	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ABW99_RS18125	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ABW99_RS18135	COG1660	Displays ATPase and GTPase activities
ABW99_RS18140	COG1194	a g-specific adenine glycosylase
ABW99_RS18145	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ABW99_RS18155	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ABW99_RS18170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABW99_RS18180	COG0193	aminoacyl-tRNA hydrolase activity
ABW99_RS18185	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABW99_RS18190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABW99_RS18195	COG0742	ribosomal rna small subunit methyltransferase
ABW99_RS18200	COG1131	(ABC) transporter
ABW99_RS18210	COG0612	Peptidase, M16
ABW99_RS18215	COG0612	Peptidase, M16
ABW99_RS18225	COG0625	glutathione transferase activity
ABW99_RS18235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABW99_RS18245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABW99_RS18265	COG1294	oxidase, subunit
ABW99_RS18275	COG0109	protoheme IX farnesyltransferase activity
ABW99_RS18280	COG1612	heme a metabolic process
ABW99_RS18310	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ABW99_RS18315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABW99_RS18330	COG2226	methyltransferase
ABW99_RS18350	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ABW99_RS18355	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ABW99_RS18360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABW99_RS18370	COG0793	Belongs to the peptidase S41A family
ABW99_RS18380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABW99_RS18385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABW99_RS18395	COG0189	ligase activity
ABW99_RS18410	COG0004	ammonium transporteR
ABW99_RS18415	COG0347	Belongs to the P(II) protein family
ABW99_RS18425	COG2960	long-chain fatty acid transporting porin activity
ABW99_RS18440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABW99_RS18450	COG0859	PFAM glycosyl transferase family 9
ABW99_RS18460	COG0321	lipoyl(octanoyl) transferase activity
ABW99_RS18470	COG0583	DNA-binding transcription factor activity
ABW99_RS18475	COG2921	Belongs to the UPF0250 family
ABW99_RS18480	COG1686	Belongs to the peptidase S11 family
ABW99_RS18505	COG1127	ABC transporter
ABW99_RS18510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABW99_RS18515	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ABW99_RS18515	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ABW99_RS18535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABW99_RS18560	COG1024	Enoyl-CoA hydratase
ABW99_RS18605	COG0646	methionine synthase
ABW99_RS18605	COG1410	methionine synthase
ABW99_RS18635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABW99_RS18640	COG0300	oxidoreductase activity
ABW99_RS18655	COG0789	Transcriptional regulator
ABW99_RS18665	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS18670	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ABW99_RS18675	COG0288	reversible hydration of carbon dioxide
ABW99_RS18680	COG0183	Belongs to the thiolase family
ABW99_RS18685	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS18695	COG3012	SEC-C Motif Domain Protein
ABW99_RS18700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABW99_RS18705	COG1024	Enoyl-CoA hydratase
ABW99_RS18715	COG0156	8-amino-7-oxononanoate synthase activity
ABW99_RS18725	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABW99_RS18750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABW99_RS18785	COG3706	GGDEF domain
ABW99_RS18795	COG0596	Alpha beta hydrolase
ABW99_RS18830	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ABW99_RS18835	COG1733	regulation of RNA biosynthetic process
ABW99_RS18845	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABW99_RS18850	COG1703	isobutyryl-CoA mutase activity
ABW99_RS18850	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ABW99_RS18850	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ABW99_RS18865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS18870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS18890	COG1024	Enoyl-CoA hydratase
ABW99_RS18900	COG1309	transcriptional regulator
ABW99_RS18930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABW99_RS18935	COG1131	(ABC) transporter
ABW99_RS18940	COG0842	Transport permease protein
ABW99_RS18950	COG1739	Uncharacterized protein family UPF0029
ABW99_RS18955	COG0322	excinuclease ABC activity
ABW99_RS18970	COG1562	ergosterol biosynthetic process
ABW99_RS18975	COG1741	Belongs to the pirin family
ABW99_RS18985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABW99_RS18990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS18995	COG0583	DNA-binding transcription factor activity
ABW99_RS19010	COG0586	Pfam SNARE associated Golgi protein
ABW99_RS19030	COG1802	Transcriptional regulator
ABW99_RS19035	COG1024	Enoyl-CoA hydratase
ABW99_RS19040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS19050	COG0277	FAD linked oxidase domain protein
ABW99_RS19050	COG0247	lactate metabolic process
ABW99_RS19060	COG2271	Major facilitator Superfamily
ABW99_RS19065	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABW99_RS19070	COG1802	Transcriptional regulator
ABW99_RS19075	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ABW99_RS19080	COG1234	tRNA 3'-trailer cleavage
ABW99_RS19090	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS19095	COG3473	Maleate cis-trans isomerase
ABW99_RS19115	COG1021	2,3-dihydroxybenzoate-AMP ligase
ABW99_RS19145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABW99_RS19150	COG0625	glutathione transferase activity
ABW99_RS19175	COG2814	Major facilitator Superfamily
ABW99_RS19180	COG1846	Transcriptional regulator
ABW99_RS19215	COG0300	oxidoreductase activity
ABW99_RS19230	COG3311	Transcriptional regulator
ABW99_RS19260	COG1280	lysine exporter protein (LysE YggA)
ABW99_RS19270	COG4521	taurine ABC transporter
ABW99_RS19310	COG1522	sequence-specific DNA binding
ABW99_RS19315	COG1280	lysine exporter protein (LysE YggA)
ABW99_RS19325	COG1917	Cupin 2, conserved barrel domain protein
ABW99_RS19325	COG2207	Transcriptional regulator
ABW99_RS19365	COG0410	ABC transporter
ABW99_RS19370	COG0154	amidase activity
ABW99_RS19380	COG1396	sequence-specific DNA binding
ABW99_RS19395	COG2337	Toxic component of a toxin-antitoxin (TA) module
ABW99_RS19405	COG0697	spore germination
ABW99_RS19425	COG0477	Major facilitator Superfamily
ABW99_RS19440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABW99_RS19445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ABW99_RS19455	COG0583	DNA-binding transcription factor activity
ABW99_RS19470	COG0415	Belongs to the DNA photolyase family
ABW99_RS19480	COG0415	Belongs to the DNA photolyase family
ABW99_RS19485	COG3046	protein related to deoxyribodipyrimidine photolyase
ABW99_RS19515	COG0596	Alpha beta hydrolase
ABW99_RS19525	COG1024	Enoyl-CoA hydratase
ABW99_RS19535	COG1414	Transcriptional regulator
ABW99_RS19545	COG0765	amino acid transport
ABW99_RS19550	COG0765	amino acid transport
ABW99_RS19560	COG1126	abc transporter atp-binding protein
ABW99_RS19570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABW99_RS19575	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABW99_RS19585	COG0642	Histidine kinase
ABW99_RS19590	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABW99_RS19590	COG1902	pentaerythritol trinitrate reductase activity
ABW99_RS19610	COG0517	IMP dehydrogenase activity
ABW99_RS19640	COG0583	DNA-binding transcription factor activity
ABW99_RS19660	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS19665	COG0625	glutathione transferase activity
ABW99_RS19670	COG0625	glutathione transferase activity
ABW99_RS19690	COG5611	PilT protein domain protein
ABW99_RS19695	COG2271	Major facilitator Superfamily
ABW99_RS19710	COG0583	DNA-binding transcription factor activity
ABW99_RS19715	COG2862	Uncharacterized protein family, UPF0114
ABW99_RS19720	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABW99_RS19725	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABW99_RS19735	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ABW99_RS19740	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS19760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABW99_RS19765	COG3246	L-lysine catabolic process to acetate
ABW99_RS19775	COG0617	tRNA 3'-terminal CCA addition
ABW99_RS19790	COG0741	lytic transglycosylase activity
ABW99_RS19795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ABW99_RS19805	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ABW99_RS19810	COG1984	allophanate hydrolase subunit 2
ABW99_RS19815	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ABW99_RS19825	COG0583	DNA-binding transcription factor activity
ABW99_RS19830	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ABW99_RS19840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABW99_RS19845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABW99_RS19865	COG0411	ABC transporter
ABW99_RS19870	COG0410	ABC transporter
ABW99_RS19880	COG0831	urea catabolic process
ABW99_RS19885	COG0832	Belongs to the urease beta subunit family
ABW99_RS19900	COG0830	nickel cation binding
ABW99_RS19905	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ABW99_RS19915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ABW99_RS19920	COG1950	PFAM Membrane protein of
ABW99_RS19925	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ABW99_RS19930	COG0708	Exodeoxyribonuclease III
ABW99_RS19935	COG1028	Short-chain dehydrogenase reductase Sdr
ABW99_RS19940	COG0667	Aldo Keto reductase
ABW99_RS19945	COG0583	DNA-binding transcription factor activity
ABW99_RS19950	COG2329	Antibiotic biosynthesis monooxygenase
ABW99_RS19965	COG0400	carboxylic ester hydrolase activity
ABW99_RS19970	COG2814	Major facilitator Superfamily
ABW99_RS19975	COG2813	Specifically methylates the guanine in position
ABW99_RS19975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABW99_RS19980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABW99_RS19985	COG1309	transcriptional regulator
ABW99_RS20000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABW99_RS20005	COG1595	DNA-templated transcription, initiation
ABW99_RS20030	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ABW99_RS20040	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ABW99_RS20045	COG3344	reverse transcriptase
ABW99_RS20060	COG0523	cobalamin synthesis protein
ABW99_RS20070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ABW99_RS20075	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ABW99_RS20085	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABW99_RS20090	COG1560	Kdo2-lipid A biosynthetic process
ABW99_RS20095	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABW99_RS20105	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS20125	COG0154	amidase activity
ABW99_RS20130	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABW99_RS20135	COG1077	Cell shape determining protein MreB Mrl
ABW99_RS20140	COG1792	Involved in formation and maintenance of cell shape
ABW99_RS20150	COG0768	penicillin binding
ABW99_RS20155	COG0772	Belongs to the SEDS family
ABW99_RS20165	COG0720	synthase
ABW99_RS20170	COG0602	queuosine metabolic process
ABW99_RS20175	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABW99_RS20185	COG2204	response regulator
ABW99_RS20185	COG2204	response regulator
ABW99_RS20190	COG5000	phosphorelay sensor kinase activity
ABW99_RS20205	COG0501	Belongs to the peptidase M48B family
ABW99_RS20210	COG1280	lysine exporter protein (LysE YggA)
ABW99_RS20215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABW99_RS20220	COG0242	peptide deformylase activity
ABW99_RS20225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABW99_RS20225	COG0758	DNA mediated transformation
ABW99_RS20240	COG0583	DNA-binding transcription factor activity
ABW99_RS20250	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ABW99_RS20255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABW99_RS20285	COG1716	ATPase activity
ABW99_RS20285	COG5001	Diguanylate cyclase
ABW99_RS20290	COG2223	nitrite transmembrane transporter activity
ABW99_RS20320	COG2814	Major facilitator Superfamily
ABW99_RS20330	COG0531	amino acid
ABW99_RS20345	COG0842	Transport permease protein
ABW99_RS20350	COG1131	(ABC) transporter
ABW99_RS20360	COG0583	DNA-binding transcription factor activity
ABW99_RS20365	COG0583	DNA-binding transcription factor activity
ABW99_RS20370	COG1960	acyl-CoA dehydrogenase activity
ABW99_RS20375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABW99_RS20380	COG0477	Major facilitator Superfamily
ABW99_RS20385	COG1522	sequence-specific DNA binding
ABW99_RS20395	COG0626	cystathionine gamma-synthase activity
ABW99_RS20400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABW99_RS20405	COG0765	amino acid transport
ABW99_RS20410	COG1126	abc transporter atp-binding protein
ABW99_RS20435	COG0583	DNA-binding transcription factor activity
ABW99_RS20460	COG0405	Gamma-glutamyltransferase
ABW99_RS20465	COG1177	transmembrane transport
ABW99_RS20470	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABW99_RS20475	COG3842	ATPase activity
ABW99_RS20485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ABW99_RS20490	COG2186	Transcriptional regulator
ABW99_RS20510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABW99_RS20515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABW99_RS20535	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABW99_RS20540	COG2733	membrane
ABW99_RS20555	COG3287	FIST C domain
ABW99_RS20555	COG2199	diguanylate cyclase activity
ABW99_RS20555	COG2200	EAL domain
ABW99_RS20580	COG1201	RNA secondary structure unwinding
ABW99_RS20605	COG0514	ATP-dependent DNA helicase (RecQ)
ABW99_RS20610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ABW99_RS20625	COG4372	Transposase
ABW99_RS20650	COG0720	synthase
ABW99_RS20690	COG3550	peptidyl-serine autophosphorylation
ABW99_RS20715	COG0592	DNA-directed DNA polymerase activity
ABW99_RS20720	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids