locus-tag	class	description
AL522_RS00060	COG1227	inorganic diphosphatase activity
AL522_RS00070	COG0148	phosphopyruvate hydratase activity
AL522_RS00075	COG0588	phosphoglycerate mutase activity
AL522_RS00080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL522_RS00085	COG0346	lactoylglutathione lyase activity
AL522_RS00110	COG2135	peptidase activity
AL522_RS00165	COG1475	DNA binding
AL522_RS00255	COG0784	Response regulator, receiver
AL522_RS00255	COG2205	protein histidine kinase activity
AL522_RS00465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL522_RS00515	COG2771	luxR family
AL522_RS00530	COG1280	lysine exporter protein (LysE YggA)
AL522_RS00535	COG1522	sequence-specific DNA binding
AL522_RS00550	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS00555	COG0386	Belongs to the glutathione peroxidase family
AL522_RS00560	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS00570	COG5001	Diguanylate cyclase
AL522_RS00590	COG1263	PTS System
AL522_RS00590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL522_RS00595	COG1874	Beta-galactosidase
AL522_RS00605	COG3833	ABC-type maltose transport systems, permease component
AL522_RS00610	COG1175	transmembrane transport
AL522_RS00615	COG2182	Extracellular solute-binding protein
AL522_RS00625	COG0583	DNA-binding transcription factor activity
AL522_RS00640	COG0583	DNA-binding transcription factor activity
AL522_RS00650	COG1280	lysine exporter protein (LysE YggA)
AL522_RS00665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL522_RS00680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL522_RS00685	COG0765	amino acid transport
AL522_RS00705	COG0006	proline dipeptidase activity
AL522_RS00710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL522_RS00715	COG0504	CTP synthase activity
AL522_RS00735	COG1349	DNA-binding transcription factor activity
AL522_RS00740	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL522_RS00745	COG3395	kinase activity
AL522_RS00755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL522_RS00760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL522_RS00765	COG2271	Major facilitator Superfamily
AL522_RS00780	COG1621	beta-fructofuranosidase activity
AL522_RS00795	COG0702	epimerase
AL522_RS00800	COG0583	DNA-binding transcription factor activity
AL522_RS00885	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL522_RS00890	COG0251	oxidation-reduction process
AL522_RS00895	COG1309	transcriptional regulator
AL522_RS00920	COG1473	amidohydrolase
AL522_RS00925	COG0596	Alpha beta hydrolase
AL522_RS00935	COG5642	Protein of unknown function (DUF2384)
AL522_RS00940	COG5654	RES domain protein
AL522_RS00945	COG0628	permease
AL522_RS00950	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AL522_RS00980	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AL522_RS00995	COG0523	cobalamin synthesis protein
AL522_RS01005	COG1012	belongs to the aldehyde dehydrogenase family
AL522_RS01055	COG2814	Major facilitator Superfamily
AL522_RS01070	COG0667	Aldo Keto reductase
AL522_RS01075	COG0583	DNA-binding transcription factor activity
AL522_RS01080	COG1201	RNA secondary structure unwinding
AL522_RS01115	COG0583	DNA-binding transcription factor activity
AL522_RS01145	COG1846	Transcriptional regulator
AL522_RS01150	COG2807	transmembrane transport
AL522_RS01155	COG1794	racemase activity, acting on amino acids and derivatives
AL522_RS01170	COG4221	oxidoreductase activity
AL522_RS01190	COG0300	oxidoreductase activity
AL522_RS01195	COG2207	Transcriptional regulator
AL522_RS01225	COG1121	(ABC) transporter
AL522_RS01230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL522_RS01235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL522_RS01240	COG0840	transmembrane signaling receptor activity
AL522_RS01255	COG2080	2 iron, 2 sulfur cluster binding
AL522_RS01260	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AL522_RS01265	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL522_RS01270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL522_RS01275	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AL522_RS01275	COG3608	succinylglutamate desuccinylase aspartoacylase
AL522_RS01285	COG4774	siderophore transport
AL522_RS01310	COG1187	pseudouridine synthase activity
AL522_RS01350	COG1280	lysine exporter protein (LysE YggA)
AL522_RS01365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL522_RS01370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL522_RS01375	COG1116	anion transmembrane transporter activity
AL522_RS01380	COG2188	Transcriptional regulator
AL522_RS01405	COG0840	transmembrane signaling receptor activity
AL522_RS01415	COG2169	Transcriptional regulator
AL522_RS01440	COG1113	amino acid transport
AL522_RS01445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL522_RS01455	COG1649	PFAM Uncharacterised BCR, COG1649
AL522_RS01460	COG0778	Nitroreductase
AL522_RS01515	COG5001	Diguanylate cyclase
AL522_RS01520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL522_RS01525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL522_RS01530	COG1116	anion transmembrane transporter activity
AL522_RS01535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL522_RS01540	COG2723	6-phospho-beta-galactosidase activity
AL522_RS01545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL522_RS01545	COG1263	PTS System
AL522_RS01550	COG1609	Transcriptional regulator
AL522_RS01555	COG1349	DNA-binding transcription factor activity
AL522_RS01565	COG0561	phosphatase activity
AL522_RS01570	COG1733	regulation of RNA biosynthetic process
AL522_RS01575	COG1064	alcohol dehydrogenase
AL522_RS01605	COG0024	Methionine aminopeptidase
AL522_RS01620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL522_RS01635	COG1309	transcriptional regulator
AL522_RS01650	COG5001	Diguanylate cyclase
AL522_RS01650	COG3300	MHYT domain
AL522_RS01655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL522_RS01660	COG0840	transmembrane signaling receptor activity
AL522_RS01685	COG3038	cytochrome b561
AL522_RS01705	COG2072	flavoprotein involved in K transport
AL522_RS01720	COG1126	abc transporter atp-binding protein
AL522_RS01725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL522_RS01730	COG0765	amino acid transport
AL522_RS01735	COG0765	amino acid transport
AL522_RS01775	COG1309	transcriptional regulator
AL522_RS01815	COG4773	Receptor
AL522_RS01825	COG5499	transcription regulator containing HTH domain
AL522_RS01835	COG1473	amidohydrolase
AL522_RS01845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL522_RS01855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL522_RS01865	COG0747	negative chemotaxis
AL522_RS01880	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AL522_RS01885	COG0076	glutamate decarboxylase activity
AL522_RS01900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL522_RS01905	COG2188	Transcriptional regulator
AL522_RS01910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL522_RS01915	COG1473	amidohydrolase
AL522_RS01920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL522_RS01925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL522_RS01940	COG1126	abc transporter atp-binding protein
AL522_RS01960	COG3141	response to X-ray
AL522_RS01965	COG3659	wide pore channel activity
AL522_RS01980	COG2723	6-phospho-beta-galactosidase activity
AL522_RS01990	COG0840	transmembrane signaling receptor activity
AL522_RS01995	COG3842	ATPase activity
AL522_RS02000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL522_RS02010	COG1175	transmembrane transport
AL522_RS02015	COG2182	Extracellular solute-binding protein
AL522_RS02020	COG1940	carbohydrate kinase activity
AL522_RS02025	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL522_RS02070	COG0693	protein deglycase activity
AL522_RS02080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL522_RS02095	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AL522_RS02105	COG3665	Urea carboxylase-associated protein
AL522_RS02110	COG0439	Biotin carboxylase
AL522_RS02115	COG0583	DNA-binding transcription factor activity
AL522_RS02130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL522_RS02140	COG0456	acetyltransferase
AL522_RS02145	COG0747	negative chemotaxis
AL522_RS02155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL522_RS02165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL522_RS02175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL522_RS02185	COG3609	addiction module antidote protein, CC2985 family
AL522_RS02200	COG4232	protein-disulfide reductase activity
AL522_RS02215	COG0346	lactoylglutathione lyase activity
AL522_RS02220	COG2223	nitrite transmembrane transporter activity
AL522_RS02225	COG1349	DNA-binding transcription factor activity
AL522_RS02240	COG3383	formate dehydrogenase (NAD+) activity
AL522_RS02260	COG0095	Lipoate-protein ligase
AL522_RS02265	COG1278	Cold shock
AL522_RS02270	COG2814	Major facilitator Superfamily
AL522_RS02290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL522_RS02295	COG0076	glutamate decarboxylase activity
AL522_RS02300	COG0477	Major facilitator Superfamily
AL522_RS02305	COG4628	conserved protein (DUF2132)
AL522_RS02315	COG3290	protein histidine kinase activity
AL522_RS02320	COG4565	transcriptional regulatory protein
AL522_RS02340	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AL522_RS02340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AL522_RS02365	COG0583	DNA-binding transcription factor activity
AL522_RS02385	COG2885	chlorophyll binding
AL522_RS02390	COG2199	diguanylate cyclase activity
AL522_RS02410	COG2182	Extracellular solute-binding protein
AL522_RS02415	COG1175	transmembrane transport
AL522_RS02430	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL522_RS02440	COG2011	ABC-type metal ion transport system permease component
AL522_RS02450	COG1464	Belongs to the NlpA lipoprotein family
AL522_RS02465	COG2011	ABC-type metal ion transport system permease component
AL522_RS02480	COG0436	Aminotransferase
AL522_RS02485	COG0477	Major facilitator Superfamily
AL522_RS02495	COG0596	Alpha beta hydrolase
AL522_RS02515	COG1454	alcohol dehydrogenase
AL522_RS02530	COG2807	transmembrane transport
AL522_RS02535	COG2066	Belongs to the glutaminase family
AL522_RS02545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL522_RS02555	COG3182	Iron-regulated membrane protein
AL522_RS02570	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL522_RS02595	COG1562	ergosterol biosynthetic process
AL522_RS02610	COG3188	usher protein
AL522_RS02615	COG3121	Chaperone
AL522_RS02640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL522_RS02665	COG1902	pentaerythritol trinitrate reductase activity
AL522_RS02715	COG1414	Transcriptional regulator
AL522_RS02735	COG3729	General stress protein
AL522_RS02745	COG0840	transmembrane signaling receptor activity
AL522_RS02750	COG1064	alcohol dehydrogenase
AL522_RS02755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AL522_RS02765	COG2916	Histone family protein nucleoid-structuring protein H-NS
AL522_RS02770	COG2203	Gaf domain
AL522_RS02770	COG5001	Diguanylate cyclase
AL522_RS02770	COG4251	negative regulation of phosphorylation
AL522_RS02770	COG3706	GGDEF domain
AL522_RS02780	COG2916	Histone family protein nucleoid-structuring protein H-NS
AL522_RS02810	COG3111	PFAM Bacterial OB fold (BOF) protein
AL522_RS02820	COG1918	ferrous iron import across plasma membrane
AL522_RS02855	COG1464	Belongs to the NlpA lipoprotein family
AL522_RS02860	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL522_RS02865	COG2011	ABC-type metal ion transport system permease component
AL522_RS02875	COG0477	Major facilitator Superfamily
AL522_RS02885	COG2011	ABC-type metal ion transport system permease component
AL522_RS02890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL522_RS02905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL522_RS02915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL522_RS02920	COG3093	addiction module antidote protein HigA
AL522_RS02970	COG5297	Belongs to the glycosyl hydrolase family 6
AL522_RS03050	COG2197	response regulator
AL522_RS03080	COG1157	protein secretion by the type III secretion system
AL522_RS03105	COG4794	Type iii secretion
AL522_RS03115	COG4792	protein secretion
AL522_RS03145	COG2076	Multidrug Resistance protein
AL522_RS03150	COG2076	Multidrug Resistance protein
AL522_RS03155	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL522_RS03160	COG0726	polysaccharide deacetylase
AL522_RS03165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL522_RS03165	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL522_RS03190	COG0673	inositol 2-dehydrogenase activity
AL522_RS03210	COG3468	outer membrane autotransporter barrel domain protein
AL522_RS03210	COG3210	domain, Protein
AL522_RS03220	COG3468	outer membrane autotransporter barrel domain protein
AL522_RS03255	COG3121	Chaperone
AL522_RS03270	COG2197	response regulator
AL522_RS03315	COG1940	carbohydrate kinase activity
AL522_RS03370	COG2851	Citrate transporter
AL522_RS03385	COG2161	toxin-antitoxin pair type II binding
AL522_RS03415	COG5001	Diguanylate cyclase
AL522_RS03415	COG3300	MHYT domain
AL522_RS03430	COG0840	transmembrane signaling receptor activity
AL522_RS03470	COG1605	Chorismate mutase
AL522_RS03475	COG2124	cytochrome p450
AL522_RS03525	COG2200	EAL domain
AL522_RS03545	COG0071	Belongs to the small heat shock protein (HSP20) family
AL522_RS03555	COG3237	CsbD-like
AL522_RS03560	COG2200	EAL domain
AL522_RS03575	COG0840	transmembrane signaling receptor activity
AL522_RS03580	COG0840	transmembrane signaling receptor activity
AL522_RS03585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL522_RS03590	COG1408	metallophosphoesterase
AL522_RS03595	COG0243	molybdopterin cofactor binding
AL522_RS03610	COG1403	HNH endonuclease
AL522_RS03660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL522_RS03665	COG2271	Major facilitator Superfamily
AL522_RS03675	COG1132	(ABC) transporter
AL522_RS03685	COG0583	DNA-binding transcription factor activity
AL522_RS03705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL522_RS03745	COG1971	Probably functions as a manganese efflux pump
AL522_RS03755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL522_RS03760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL522_RS03770	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AL522_RS03780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL522_RS03785	COG0625	glutathione transferase activity
AL522_RS03795	COG0300	oxidoreductase activity
AL522_RS03800	COG0583	DNA-binding transcription factor activity
AL522_RS03805	COG1295	ribonuclease BN
AL522_RS03810	COG0477	Major facilitator Superfamily
AL522_RS03820	COG0583	DNA-binding transcription factor activity
AL522_RS03830	COG0129	dihydroxy-acid dehydratase activity
AL522_RS03840	COG3978	acetolactate synthase activity
AL522_RS03855	COG0606	chelatase, subunit chli
AL522_RS03860	COG3085	chromosome segregation
AL522_RS03865	COG0583	DNA-binding transcription factor activity
AL522_RS03910	COG4206	TonB-dependent receptor
AL522_RS03925	COG1309	transcriptional regulator
AL522_RS03930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL522_RS03935	COG0583	DNA-binding transcription factor activity
AL522_RS03940	COG0678	peroxiredoxin activity
AL522_RS03940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL522_RS03950	COG0137	argininosuccinate synthase activity
AL522_RS03965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL522_RS03970	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL522_RS03975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL522_RS03980	COG0460	homoserine dehydrogenase
AL522_RS03980	COG0527	aspartate kinase activity
AL522_RS03985	COG0626	cystathionine gamma-synthase activity
AL522_RS03990	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AL522_RS03995	COG0254	rRNA binding
AL522_RS04000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL522_RS04005	COG1609	Transcriptional regulator
AL522_RS04010	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL522_RS04015	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL522_RS04025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL522_RS04030	COG3074	FtsZ-dependent cytokinesis
AL522_RS04035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL522_RS04045	COG1494	fructose-1,6-bisphosphatase
AL522_RS04050	COG2814	Major facilitator Superfamily
AL522_RS04060	COG3152	Membrane
AL522_RS04070	COG0149	triose-phosphate isomerase activity
AL522_RS04075	COG2134	cdp-diacylglycerol pyrophosphatase
AL522_RS04080	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AL522_RS04085	COG0205	6-phosphofructokinase activity
AL522_RS04095	COG3729	General stress protein
AL522_RS04100	COG3678	ATP-independent chaperone mediated protein folding
AL522_RS04105	COG0745	RESPONSE REGULATOR receiver
AL522_RS04110	COG2205	protein histidine kinase activity
AL522_RS04115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL522_RS04125	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL522_RS04135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL522_RS04140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL522_RS04145	COG4942	peptidase
AL522_RS04150	COG2861	carbohydrate metabolic process
AL522_RS04155	COG0438	transferase activity, transferring glycosyl groups
AL522_RS04165	COG1063	alcohol dehydrogenase
AL522_RS04170	COG0156	8-amino-7-oxononanoate synthase activity
AL522_RS04175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL522_RS04180	COG0859	PFAM glycosyl transferase family 9
AL522_RS04185	COG0859	PFAM glycosyl transferase family 9
AL522_RS04200	COG1216	Glycosyl transferase, family 2
AL522_RS04205	COG0859	PFAM glycosyl transferase family 9
AL522_RS04215	COG1519	Transferase
AL522_RS04240	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL522_RS04245	COG2003	Belongs to the UPF0758 family
AL522_RS04250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL522_RS04270	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL522_RS04275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL522_RS04285	COG1561	YicC-like family, N-terminal region
AL522_RS04300	COG1560	Kdo2-lipid A biosynthetic process
AL522_RS04320	COG2244	polysaccharide biosynthetic process
AL522_RS04325	COG2860	membrane
AL522_RS04340	COG1758	RNA polymerase activity
AL522_RS04345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL522_RS04350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL522_RS04355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL522_RS04360	COG2233	PERMEase
AL522_RS04370	COG2982	Protein involved in outer membrane biogenesis
AL522_RS04375	COG0456	acetyltransferase
AL522_RS04390	COG1011	Hydrolase
AL522_RS04405	COG3852	Histidine kinase
AL522_RS04415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL522_RS04420	COG3078	GTPase activator activity
AL522_RS04435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL522_RS04435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL522_RS04450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL522_RS04455	COG3084	Protein conserved in bacteria
AL522_RS04460	COG0746	molybdenum cofactor guanylyltransferase activity
AL522_RS04465	COG1763	Mo-molybdopterin cofactor biosynthetic process
AL522_RS04490	COG0477	Major facilitator Superfamily
AL522_RS04495	COG1609	Transcriptional regulator
AL522_RS04500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL522_RS04505	COG1879	ABC-type sugar transport system periplasmic component
AL522_RS04510	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL522_RS04515	COG1129	ABC transporter
AL522_RS04525	COG3111	PFAM Bacterial OB fold (BOF) protein
AL522_RS04530	COG0745	RESPONSE REGULATOR receiver
AL522_RS04535	COG0642	Histidine kinase
AL522_RS04550	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AL522_RS04555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL522_RS04560	COG1522	sequence-specific DNA binding
AL522_RS04565	COG0716	FMN binding
AL522_RS04575	COG0357	Ribosomal RNA small subunit methyltransferase G
AL522_RS04580	COG3312	ion transport
AL522_RS04585	COG0356	it plays a direct role in the translocation of protons across the membrane
AL522_RS04595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL522_RS04600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL522_RS04605	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL522_RS04610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL522_RS04615	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL522_RS04625	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL522_RS04635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL522_RS04640	COG0573	inorganic phosphate transmembrane transporter activity
AL522_RS04645	COG0581	inorganic phosphate transmembrane transporter activity
AL522_RS04650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL522_RS04655	COG0704	Plays a role in the regulation of phosphate uptake
AL522_RS04660	COG2814	Major facilitator Superfamily
AL522_RS04665	COG1070	Carbohydrate kinase
AL522_RS04670	COG2115	Belongs to the xylose isomerase family
AL522_RS04680	COG4213	ABC transporter substrate-binding protein
AL522_RS04690	COG4214	carbohydrate transport
AL522_RS04695	COG1609	Transcriptional regulator
AL522_RS04695	COG2207	Transcriptional regulator
AL522_RS04700	COG2814	Major facilitator Superfamily
AL522_RS04710	COG1484	DNA-dependent DNA replication
AL522_RS04725	COG5571	outer membrane autotransporter
AL522_RS04730	COG2818	Glycosylase
AL522_RS04735	COG2885	chlorophyll binding
AL522_RS04745	COG1609	Transcriptional regulator
AL522_RS04755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL522_RS04770	COG3977	Valine--pyruvate aminotransferase
AL522_RS04775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL522_RS04785	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL522_RS04800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL522_RS04805	COG0697	spore germination
AL522_RS04815	COG5645	(Lipo)protein
AL522_RS04820	COG0823	Involved in the tonB-independent uptake of proteins
AL522_RS04825	COG0561	phosphatase activity
AL522_RS04830	COG2731	YhcH YjgK YiaL family protein
AL522_RS04835	COG0187	DNA topoisomerase II activity
AL522_RS04840	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL522_RS04850	COG0592	DNA-directed DNA polymerase activity
AL522_RS04855	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL522_RS04860	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL522_RS04865	COG0594	ribonuclease P activity
AL522_RS04875	COG0706	membrane insertase activity
AL522_RS04895	COG2252	PERMEase
AL522_RS04900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL522_RS04910	COG3274	enterobacterial common antigen metabolic process
AL522_RS04915	COG0752	glycyl-tRNA synthetase alpha subunit
AL522_RS04920	COG0751	glycine-tRNA ligase activity
AL522_RS04935	COG0625	glutathione transferase activity
AL522_RS04945	COG2864	formate dehydrogenase
AL522_RS04950	COG0437	4 iron, 4 sulfur cluster binding
AL522_RS04955	COG0243	molybdopterin cofactor binding
AL522_RS04955	COG3383	formate dehydrogenase (NAD+) activity
AL522_RS04965	COG1349	DNA-binding transcription factor activity
AL522_RS04970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL522_RS04975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL522_RS04980	COG2990	Protein conserved in bacteria
AL522_RS04990	COG3722	fumarate hydratase activity
AL522_RS05000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL522_RS05000	COG2213	PTS system mannitol-specific
AL522_RS05015	COG2944	sequence-specific DNA binding
AL522_RS05025	COG1846	Transcriptional regulator
AL522_RS05030	COG1764	response to oxidative stress
AL522_RS05035	COG2194	sulfuric ester hydrolase activity
AL522_RS05045	COG0747	negative chemotaxis
AL522_RS05050	COG0601	transmembrane transport
AL522_RS05055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL522_RS05060	COG0444	Belongs to the ABC transporter superfamily
AL522_RS05065	COG4608	Belongs to the ABC transporter superfamily
AL522_RS05075	COG0455	bacterial-type flagellum organization
AL522_RS05080	COG1215	transferase activity, transferring glycosyl groups
AL522_RS05085	COG1215	transferase activity, transferring glycosyl groups
AL522_RS05090	COG0457	Tetratricopeptide repeat
AL522_RS05100	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AL522_RS05105	COG2194	sulfuric ester hydrolase activity
AL522_RS05135	COG1215	transferase activity, transferring glycosyl groups
AL522_RS05140	COG3118	belongs to the thioredoxin family
AL522_RS05140	COG0457	Tetratricopeptide repeat
AL522_RS05145	COG2199	diguanylate cyclase activity
AL522_RS05145	COG2200	EAL domain
AL522_RS05160	COG0612	Peptidase, M16
AL522_RS05175	COG2200	EAL domain
AL522_RS05180	COG2982	Protein involved in outer membrane biogenesis
AL522_RS05185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL522_RS05195	COG0248	Ppx GppA phosphatase
AL522_RS05205	COG3118	belongs to the thioredoxin family
AL522_RS05210	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL522_RS05215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL522_RS05220	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AL522_RS05225	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL522_RS05230	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AL522_RS05235	COG1088	dTDP-glucose 4,6-dehydratase activity
AL522_RS05240	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AL522_RS05245	COG0456	acetyltransferase
AL522_RS05250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL522_RS05255	COG2244	polysaccharide biosynthetic process
AL522_RS05260	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL522_RS05270	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AL522_RS05300	COG3071	HemY protein
AL522_RS05305	COG2959	enzyme of heme biosynthesis
AL522_RS05310	COG1587	Uroporphyrinogen-III synthase
AL522_RS05315	COG0181	hydroxymethylbilane synthase activity
AL522_RS05330	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL522_RS05345	COG1011	Hydrolase
AL522_RS05350	COG0210	DNA helicase
AL522_RS05360	COG3180	Ammonia monooxygenase
AL522_RS05365	COG2962	Rard protein
AL522_RS05370	COG2050	protein possibly involved in aromatic compounds catabolism
AL522_RS05385	COG1280	lysine exporter protein (LysE YggA)
AL522_RS05395	COG1280	lysine exporter protein (LysE YggA)
AL522_RS05400	COG2267	carboxylic ester hydrolase activity
AL522_RS05405	COG0561	phosphatase activity
AL522_RS05410	COG2271	Major facilitator Superfamily
AL522_RS05420	COG4807	Protein conserved in bacteria
AL522_RS05425	COG0583	DNA-binding transcription factor activity
AL522_RS05430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL522_RS05435	COG0412	Dienelactone hydrolase
AL522_RS05450	COG1322	Protein conserved in bacteria
AL522_RS05455	COG2226	methyltransferase
AL522_RS05465	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL522_RS05470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL522_RS05480	COG0805	protein transport
AL522_RS05485	COG0084	hydrolase, TatD family'
AL522_RS05500	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL522_RS05520	COG0006	proline dipeptidase activity
AL522_RS05525	COG1739	Uncharacterized protein family UPF0029
AL522_RS05560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL522_RS05565	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AL522_RS05565	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AL522_RS05605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL522_RS05610	COG0250	Participates in transcription elongation, termination and antitermination
AL522_RS05615	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AL522_RS05625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL522_RS05630	COG0222	ribosome binding
AL522_RS05635	COG0085	RNA polymerase activity
AL522_RS05640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL522_RS05650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL522_RS05660	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AL522_RS05665	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AL522_RS05675	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL522_RS05705	COG0138	bifunctional purine biosynthesis protein purh
AL522_RS05730	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AL522_RS05735	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL522_RS05755	COG0646	methionine synthase
AL522_RS05755	COG1410	methionine synthase
AL522_RS05760	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL522_RS05790	COG0527	aspartate kinase activity
AL522_RS05805	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL522_RS05810	COG3842	ATPase activity
AL522_RS05845	COG3161	chorismate lyase activity
AL522_RS05850	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AL522_RS05860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL522_RS05870	COG0534	Mate efflux family protein
AL522_RS05880	COG0735	belongs to the Fur family
AL522_RS05890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL522_RS05910	COG1522	sequence-specific DNA binding
AL522_RS05920	COG1448	Aminotransferase
AL522_RS05930	COG2315	Protein conserved in bacteria
AL522_RS05935	COG1064	alcohol dehydrogenase
AL522_RS05940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL522_RS05945	COG0629	single-stranded DNA binding
AL522_RS05960	COG0697	spore germination
AL522_RS05990	COG0789	Transcriptional regulator
AL522_RS06000	COG2252	PERMEase
AL522_RS06005	COG0025	NhaP-type Na H and K H
AL522_RS06010	COG0583	DNA-binding transcription factor activity
AL522_RS06020	COG1346	cytolysis
AL522_RS06030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL522_RS06035	COG3162	membrane
AL522_RS06045	COG1301	dicarboxylic acid transport
AL522_RS06055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL522_RS06055	COG1263	PTS System
AL522_RS06060	COG0840	transmembrane signaling receptor activity
AL522_RS06100	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AL522_RS06120	COG2271	Major facilitator Superfamily
AL522_RS06125	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL522_RS06130	COG1473	amidohydrolase
AL522_RS06135	COG1473	amidohydrolase
AL522_RS06140	COG0583	DNA-binding transcription factor activity
AL522_RS06150	COG3248	Nucleoside-binding outer membrane protein
AL522_RS06155	COG0642	Histidine kinase
AL522_RS06165	COG4977	sequence-specific DNA binding
AL522_RS06180	COG4993	Dehydrogenase
AL522_RS06200	COG2971	BadF BadG BcrA BcrD
AL522_RS06205	COG1940	carbohydrate kinase activity
AL522_RS06230	COG1175	transmembrane transport
AL522_RS06235	COG0395	ABC-type sugar transport system, permease component
AL522_RS06245	COG0473	3-isopropylmalate dehydrogenase activity
AL522_RS06265	COG0625	glutathione transferase activity
AL522_RS06270	COG1082	Xylose isomerase domain protein TIM barrel
AL522_RS06300	COG3539	Fimbrial protein
AL522_RS06310	COG3121	Chaperone
AL522_RS06325	COG1309	transcriptional regulator
AL522_RS06335	COG1324	tolerance protein
AL522_RS06340	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL522_RS06350	COG3030	protein affecting phage T7 exclusion by the F plasmid
AL522_RS06355	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL522_RS06370	COG1509	lysine 2,3-aminomutase activity
AL522_RS06375	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL522_RS06390	COG3040	lipid binding
AL522_RS06395	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AL522_RS06400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL522_RS06405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL522_RS06410	COG3105	Protein conserved in bacteria
AL522_RS06415	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL522_RS06420	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL522_RS06425	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL522_RS06430	COG0625	glutathione transferase activity
AL522_RS06435	COG2969	positive regulation of protein catabolic process
AL522_RS06440	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL522_RS06445	COG0070	glutamate synthase
AL522_RS06445	COG0069	glutamate synthase activity
AL522_RS06445	COG0067	glutamate synthase
AL522_RS06450	COG0784	Response regulator, receiver
AL522_RS06450	COG2198	Histidine kinase
AL522_RS06450	COG5002	protein histidine kinase activity
AL522_RS06460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL522_RS06475	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL522_RS06480	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL522_RS06485	COG1137	ATPase activity
AL522_RS06490	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL522_RS06495	COG3117	lipopolysaccharide transmembrane transporter activity
AL522_RS06500	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AL522_RS06510	COG0530	calcium, potassium:sodium antiporter activity
AL522_RS06515	COG1127	ABC transporter
AL522_RS06520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL522_RS06525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL522_RS06530	COG2854	intermembrane phospholipid transfer
AL522_RS06535	COG3113	response to antibiotic
AL522_RS06540	COG5007	Belongs to the BolA IbaG family
AL522_RS06550	COG3423	Transcriptional regulator
AL522_RS06555	COG0142	geranyltranstransferase activity
AL522_RS06560	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL522_RS06565	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AL522_RS06570	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL522_RS06580	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS06585	COG1535	isochorismatase
AL522_RS06585	COG3433	isochorismatase activity
AL522_RS06590	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL522_RS06595	COG1169	isochorismate synthase
AL522_RS06600	COG4592	Periplasmic binding protein
AL522_RS06610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL522_RS06615	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL522_RS06620	COG1120	ATPase activity
AL522_RS06625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL522_RS06625	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AL522_RS06635	COG2382	esterase
AL522_RS06640	COG4771	TonB-dependent receptor
AL522_RS06645	COG2027	D-alanyl-D-alanine carboxypeptidase
AL522_RS06655	COG1534	Rna-binding protein
AL522_RS06660	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL522_RS06670	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL522_RS06675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL522_RS06685	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL522_RS06700	COG0779	Required for maturation of 30S ribosomal subunits
AL522_RS06705	COG0195	Participates in both transcription termination and antitermination
AL522_RS06715	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL522_RS06720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL522_RS06725	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL522_RS06730	COG1185	polyribonucleotide nucleotidyltransferase activity
AL522_RS06745	COG0513	Belongs to the DEAD box helicase family
AL522_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS06755	COG2207	Transcriptional regulator
AL522_RS06760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL522_RS06765	COG0826	peptidase U32
AL522_RS06770	COG0826	peptidase U32
AL522_RS06775	COG3154	lipid carrier protein
AL522_RS06780	COG3153	acetyltransferase
AL522_RS06785	COG2827	Endonuclease containing a URI domain
AL522_RS06790	COG3787	Belongs to the UPF0306 family
AL522_RS06795	COG0693	protein deglycase activity
AL522_RS06800	COG0702	epimerase
AL522_RS06805	COG0602	queuosine metabolic process
AL522_RS06810	COG1328	CTP reductase activity
AL522_RS06820	COG1609	Transcriptional regulator
AL522_RS06830	COG0768	penicillin binding
AL522_RS06835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL522_RS06840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL522_RS06855	COG0204	Acyl-transferase
AL522_RS06855	COG0318	PFAM AMP-dependent synthetase and ligase
AL522_RS06870	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AL522_RS06875	COG0540	Belongs to the ATCase OTCase family
AL522_RS06880	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL522_RS06885	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AL522_RS06910	COG0525	valine-tRNA ligase activity
AL522_RS06915	COG2927	DNA polymerase III (CHI subunit)
AL522_RS06920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL522_RS06925	COG0795	lipopolysaccharide-transporting ATPase activity
AL522_RS06930	COG0795	lipopolysaccharide-transporting ATPase activity
AL522_RS06950	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL522_RS06955	COG1129	ABC transporter
AL522_RS06960	COG1609	Transcriptional regulator
AL522_RS06990	COG2733	membrane
AL522_RS06995	COG0433	COG0433 Predicted ATPase
AL522_RS07090	COG0582	viral genome integration into host DNA
AL522_RS07205	COG2134	cdp-diacylglycerol pyrophosphatase
AL522_RS07215	COG2274	protein secretion by the type I secretion system
AL522_RS07230	COG3318	Belongs to the UPF0149 family
AL522_RS07230	COG3012	SEC-C Motif Domain Protein
AL522_RS07250	COG1126	abc transporter atp-binding protein
AL522_RS07255	COG0765	amino acid transport
AL522_RS07265	COG1609	Transcriptional regulator
AL522_RS07290	COG1942	4-Oxalocrotonate Tautomerase
AL522_RS07315	COG0477	Major facilitator Superfamily
AL522_RS07320	COG1609	Transcriptional regulator
AL522_RS07330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL522_RS07335	COG4114	ferric iron reductase
AL522_RS07340	COG3706	GGDEF domain
AL522_RS07365	COG2813	Specifically methylates the guanine in position
AL522_RS07370	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AL522_RS07375	COG0456	acetyltransferase
AL522_RS07380	COG1011	Hydrolase
AL522_RS07385	COG3726	membrane protein affecting hemolysin expression
AL522_RS07390	COG0560	Phosphoserine phosphatase
AL522_RS07405	COG0604	alcohol dehydrogenase
AL522_RS07415	COG0488	(ABC) transporter
AL522_RS07425	COG1349	DNA-binding transcription factor activity
AL522_RS07435	COG1129	ABC transporter
AL522_RS07455	COG1802	Transcriptional regulator
AL522_RS07460	COG0439	Biotin carboxylase
AL522_RS07470	COG0741	lytic transglycosylase activity
AL522_RS07480	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AL522_RS07490	COG2207	Transcriptional regulator
AL522_RS07490	COG3708	Transcriptional regulator
AL522_RS07495	COG3045	CreA protein
AL522_RS07500	COG0745	RESPONSE REGULATOR receiver
AL522_RS07505	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AL522_RS07515	COG0527	aspartate kinase activity
AL522_RS07515	COG0460	homoserine dehydrogenase
AL522_RS07530	COG3022	response to hydroperoxide
AL522_RS07540	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL522_RS07545	COG0477	Major facilitator Superfamily
AL522_RS07550	COG1584	GPR1 FUN34 yaaH family protein
AL522_RS07560	COG0484	heat shock protein binding
AL522_RS07570	COG0583	DNA-binding transcription factor activity
AL522_RS07575	COG0268	Binds directly to 16S ribosomal RNA
AL522_RS07580	COG0196	riboflavin kinase activity
AL522_RS07585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL522_RS07590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL522_RS07595	COG1047	Peptidyl-prolyl cis-trans
AL522_RS07600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL522_RS07605	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AL522_RS07610	COG0505	Belongs to the CarA family
AL522_RS07640	COG2967	ApaG domain
AL522_RS07645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL522_RS07650	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL522_RS07655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL522_RS07660	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL522_RS07665	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL522_RS07670	COG0564	pseudouridine synthase activity
AL522_RS07675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL522_RS07680	COG0417	DNA replication proofreading
AL522_RS07685	COG0586	Pfam SNARE associated Golgi protein
AL522_RS07695	COG1178	ABC-type Fe3 transport system permease component
AL522_RS07700	COG4143	(ABC) transporter
AL522_RS07710	COG2814	Major facilitator Superfamily
AL522_RS07715	COG0066	3-isopropylmalate dehydratase activity
AL522_RS07720	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AL522_RS07730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL522_RS07740	COG0028	Belongs to the TPP enzyme family
AL522_RS07755	COG2001	Belongs to the MraZ family
AL522_RS07770	COG0768	penicillin binding
AL522_RS07780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL522_RS07795	COG0772	Belongs to the SEDS family
AL522_RS07805	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL522_RS07810	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL522_RS07820	COG0849	cell division
AL522_RS07825	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL522_RS07830	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL522_RS07845	COG0494	nUDIX hydrolase
AL522_RS07850	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AL522_RS07860	COG0237	dephospho-CoA kinase activity
AL522_RS07865	COG0516	GMP reductase activity
AL522_RS07870	COG1459	type II secretion system
AL522_RS07875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL522_RS07880	COG4969	Belongs to the N-Me-Phe pilin family
AL522_RS07890	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL522_RS07895	COG3725	Membrane protein required for beta-lactamase induction
AL522_RS07900	COG3940	Belongs to the glycosyl hydrolase 43 family
AL522_RS07905	COG2211	Major facilitator Superfamily
AL522_RS07910	COG1113	amino acid transport
AL522_RS07915	COG2186	Transcriptional regulator
AL522_RS07920	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL522_RS07925	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL522_RS07930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL522_RS07960	COG3479	Phenolic acid decarboxylase
AL522_RS07970	COG3112	Uncharacterised protein family (UPF0231)
AL522_RS07985	COG3395	kinase activity
AL522_RS07990	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL522_RS07995	COG1349	DNA-binding transcription factor activity
AL522_RS08010	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL522_RS08025	COG0626	cystathionine gamma-synthase activity
AL522_RS08035	COG0288	reversible hydration of carbon dioxide
AL522_RS08040	COG1131	(ABC) transporter
AL522_RS08045	COG0842	Transport permease protein
AL522_RS08055	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AL522_RS08060	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL522_RS08065	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL522_RS08070	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL522_RS08075	COG0617	tRNA 3'-terminal CCA addition
AL522_RS08085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL522_RS08100	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AL522_RS08105	COG1643	Atp-dependent helicase
AL522_RS08110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL522_RS08115	COG4774	siderophore transport
AL522_RS08120	COG1120	ATPase activity
AL522_RS08125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL522_RS08140	COG0316	Belongs to the HesB IscA family
AL522_RS08150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL522_RS08155	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL522_RS08165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL522_RS08170	COG3835	regulator
AL522_RS08185	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL522_RS08195	COG0052	Belongs to the universal ribosomal protein uS2 family
AL522_RS08200	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL522_RS08205	COG0528	UMP kinase activity
AL522_RS08210	COG0233	cytoplasmic translational termination
AL522_RS08215	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL522_RS08220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL522_RS08225	COG0575	Belongs to the CDS family
AL522_RS08235	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL522_RS08240	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL522_RS08250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL522_RS08260	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL522_RS08265	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AL522_RS08275	COG0825	malonyl-CoA metabolic process
AL522_RS08280	COG1982	Orn Lys Arg decarboxylase major
AL522_RS08285	COG0346	lactoylglutathione lyase activity
AL522_RS08290	COG0037	tRNA processing
AL522_RS08300	COG4568	rho-dependent transcription termination
AL522_RS08315	COG0442	prolyl-tRNA aminoacylation
AL522_RS08320	COG1720	tRNA m6t6A37 methyltransferase activity
AL522_RS08335	COG2011	ABC-type metal ion transport system permease component
AL522_RS08340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL522_RS08345	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL522_RS08375	COG0583	DNA-binding transcription factor activity
AL522_RS08380	COG3021	interspecies interaction between organisms
AL522_RS08385	COG1388	LysM domain
AL522_RS08385	COG0741	lytic transglycosylase activity
AL522_RS08390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL522_RS08395	COG2226	methyltransferase
AL522_RS08400	COG0328	RNA-DNA hybrid ribonuclease activity
AL522_RS08415	COG1953	Uracil, thiamine, allantoin
AL522_RS08465	COG0765	amino acid transport
AL522_RS08470	COG0765	amino acid transport
AL522_RS08480	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL522_RS08495	COG2351	hydroxyisourate hydrolase activity
AL522_RS08500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL522_RS08505	COG0436	Aminotransferase
AL522_RS08515	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AL522_RS08520	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AL522_RS08540	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL522_RS08545	COG0121	glutamine amidotransferase
AL522_RS08550	COG3034	peptidoglycan biosynthetic process
AL522_RS08565	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL522_RS08570	COG1129	ABC transporter
AL522_RS08575	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL522_RS08585	COG1073	alpha beta
AL522_RS08600	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL522_RS08605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL522_RS08610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL522_RS08650	COG1278	Cold shock
AL522_RS08660	COG0840	transmembrane signaling receptor activity
AL522_RS08670	COG0835	chemotaxis
AL522_RS08670	COG0784	Response regulator, receiver
AL522_RS08680	COG0513	Belongs to the DEAD box helicase family
AL522_RS08690	COG0402	S-adenosylhomocysteine deaminase activity
AL522_RS08700	COG2807	transmembrane transport
AL522_RS08705	COG1620	l-lactate permease
AL522_RS08710	COG2186	Transcriptional regulator
AL522_RS08720	COG1764	response to oxidative stress
AL522_RS08735	COG5001	Diguanylate cyclase
AL522_RS08780	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL522_RS08790	COG3416	Protein conserved in bacteria
AL522_RS08795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL522_RS08805	COG1414	Transcriptional regulator
AL522_RS08820	COG4126	flavin adenine dinucleotide binding
AL522_RS08825	COG3123	guanosine phosphorylase activity
AL522_RS08830	COG2974	May be involved in recombination
AL522_RS08835	COG1940	carbohydrate kinase activity
AL522_RS08875	COG0419	ATPase involved in DNA repair
AL522_RS08880	COG0420	3'-5' exonuclease activity
AL522_RS08885	COG0745	RESPONSE REGULATOR receiver
AL522_RS08890	COG5002	protein histidine kinase activity
AL522_RS08900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL522_RS08910	COG1113	amino acid transport
AL522_RS08920	COG0483	inositol monophosphate 1-phosphatase activity
AL522_RS08930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL522_RS08935	COG0582	viral genome integration into host DNA
AL522_RS09025	COG1396	sequence-specific DNA binding
AL522_RS09170	COG5484	DNA packaging
AL522_RS09170	COG3728	DNA packaging
AL522_RS09175	COG5410	chromosome segregation
AL522_RS09315	COG0343	queuine tRNA-ribosyltransferase activity
AL522_RS09320	COG1862	Preprotein translocase
AL522_RS09325	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL522_RS09330	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL522_RS09335	COG4238	major outer membrane lipoprotein
AL522_RS09340	COG1652	LysM domain
AL522_RS09350	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL522_RS09350	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL522_RS09355	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL522_RS09360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL522_RS09365	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AL522_RS09370	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL522_RS09375	COG0667	Aldo Keto reductase
AL522_RS09380	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL522_RS09385	COG0142	geranyltranstransferase activity
AL522_RS09390	COG1722	exodeoxyribonuclease VII activity
AL522_RS09405	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL522_RS09410	COG1666	GTP binding
AL522_RS09415	COG2814	Major facilitator Superfamily
AL522_RS09420	COG0109	protoheme IX farnesyltransferase activity
AL522_RS09425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL522_RS09430	COG1845	cytochrome c oxidase, subunit III
AL522_RS09435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL522_RS09440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL522_RS09445	COG2223	nitrite transmembrane transporter activity
AL522_RS09450	COG3056	Lipoprotein
AL522_RS09455	COG0271	Belongs to the BolA IbaG family
AL522_RS09480	COG0776	regulation of translation
AL522_RS09485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL522_RS09490	COG1555	photosystem II stabilization
AL522_RS09495	COG0824	Thioesterase
AL522_RS09505	COG4533	DNA binding
AL522_RS09515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL522_RS09520	COG1522	sequence-specific DNA binding
AL522_RS09525	COG1132	(ABC) transporter
AL522_RS09530	COG1132	(ABC) transporter
AL522_RS09535	COG0347	Belongs to the P(II) protein family
AL522_RS09540	COG0004	ammonium transporteR
AL522_RS09545	COG1946	Acyl-CoA thioesterase
AL522_RS09550	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AL522_RS09555	COG3695	enzyme binding
AL522_RS09580	COG1121	(ABC) transporter
AL522_RS09585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL522_RS09590	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL522_RS09595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL522_RS09600	COG0254	rRNA binding
AL522_RS09605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL522_RS09610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL522_RS09615	COG1309	transcriptional regulator
AL522_RS09625	COG2261	transglycosylase associated protein
AL522_RS09635	COG2832	Protein of unknown function (DUF454)
AL522_RS09640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL522_RS09645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL522_RS09650	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AL522_RS09655	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL522_RS09660	COG0326	Molecular chaperone. Has ATPase activity
AL522_RS09670	COG0563	adenylate kinase activity
AL522_RS09675	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL522_RS09680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL522_RS09685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL522_RS09685	COG4651	solute:proton antiporter activity
AL522_RS09690	COG0737	Belongs to the 5'-nucleotidase family
AL522_RS09710	COG3735	TraB family
AL522_RS09715	COG2217	Heavy metal translocating P-type atpase
AL522_RS09720	COG0789	Transcriptional regulator
AL522_RS09725	COG1585	Membrane protein implicated in regulation of membrane protease activity
AL522_RS09730	COG0330	HflC and HflK could
AL522_RS09735	COG3118	belongs to the thioredoxin family
AL522_RS09740	COG0300	oxidoreductase activity
AL522_RS09745	COG2755	lipolytic protein G-D-S-L family
AL522_RS09750	COG4181	ATPase activity
AL522_RS09755	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL522_RS09760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL522_RS09765	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL522_RS09775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL522_RS09780	COG0215	cysteine-tRNA ligase activity
AL522_RS09785	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL522_RS09790	COG2501	S4 domain
AL522_RS09795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL522_RS09860	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AL522_RS09880	COG0598	Magnesium transport protein CorA
AL522_RS09895	COG1597	lipid kinase activity
AL522_RS09915	COG0628	permease
AL522_RS09930	COG2323	membrane
AL522_RS09945	COG1063	alcohol dehydrogenase
AL522_RS09955	COG0814	amino acid
AL522_RS09970	COG0561	phosphatase activity
AL522_RS09975	COG1454	alcohol dehydrogenase
AL522_RS09980	COG2610	gluconate transmembrane transporter activity
AL522_RS09995	COG1278	Cold shock
AL522_RS10015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL522_RS10030	COG1126	abc transporter atp-binding protein
AL522_RS10035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL522_RS10040	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL522_RS10045	COG0321	lipoyl(octanoyl) transferase activity
AL522_RS10050	COG2921	Belongs to the UPF0250 family
AL522_RS10055	COG1686	Belongs to the peptidase S11 family
AL522_RS10060	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL522_RS10065	COG0772	Belongs to the SEDS family
AL522_RS10070	COG0768	penicillin binding
AL522_RS10075	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL522_RS10080	COG0799	negative regulation of ribosome biogenesis
AL522_RS10090	COG1466	dna polymerase III delta subunit
AL522_RS10095	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AL522_RS10100	COG0495	leucyl-tRNA aminoacylation
AL522_RS10105	COG2888	peptidyl-tyrosine sulfation
AL522_RS10110	COG1126	abc transporter atp-binding protein
AL522_RS10115	COG0765	amino acid transport
AL522_RS10120	COG0765	amino acid transport
AL522_RS10130	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL522_RS10145	COG1702	phosphate starvation-inducible protein PhoH
AL522_RS10150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL522_RS10155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL522_RS10195	COG0367	asparagine synthase
AL522_RS10200	COG0647	UMP catabolic process
AL522_RS10205	COG1846	Transcriptional regulator
AL522_RS10205	COG1940	carbohydrate kinase activity
AL522_RS10210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL522_RS10215	COG0363	glucosamine-6-phosphate deaminase activity
AL522_RS10220	COG2190	(PTS) system
AL522_RS10220	COG1263	PTS System
AL522_RS10220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL522_RS10225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL522_RS10235	COG0735	belongs to the Fur family
AL522_RS10240	COG0716	FMN binding
AL522_RS10250	COG0596	Alpha beta hydrolase
AL522_RS10255	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AL522_RS10260	COG0033	Phosphoglucomutase
AL522_RS10265	COG0745	RESPONSE REGULATOR receiver
AL522_RS10275	COG3272	Protein of unknown function (DUF1722)
AL522_RS10290	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL522_RS10295	COG1984	allophanate hydrolase subunit 2
AL522_RS10315	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL522_RS10325	COG0372	Belongs to the citrate synthase family
AL522_RS10335	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL522_RS10340	COG1053	succinate dehydrogenase
AL522_RS10345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL522_RS10350	COG0567	Dehydrogenase, E1 component
AL522_RS10355	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL522_RS10360	COG0045	succinate-CoA ligase (ADP-forming) activity
AL522_RS10365	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL522_RS10370	COG1271	oxidase subunit
AL522_RS10375	COG1294	oxidase, subunit
AL522_RS10380	COG4890	Cyd operon protein YbgT
AL522_RS10385	COG3790	cyd operon protein YbgE
AL522_RS10390	COG0824	Thioesterase
AL522_RS10395	COG0811	peptide transport
AL522_RS10400	COG0848	biopolymer transport protein
AL522_RS10405	COG3064	Membrane
AL522_RS10415	COG2885	chlorophyll binding
AL522_RS10420	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AL522_RS10450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL522_RS10455	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL522_RS10465	COG1230	cation diffusion facilitator family transporter
AL522_RS10470	COG2198	Histidine kinase
AL522_RS10470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL522_RS10470	COG0784	Response regulator, receiver
AL522_RS10470	COG2205	protein histidine kinase activity
AL522_RS10485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL522_RS10490	COG0588	phosphoglycerate mutase activity
AL522_RS10495	COG2017	converts alpha-aldose to the beta-anomer
AL522_RS10505	COG1085	galactose-1-phosphate uridylyltransferase
AL522_RS10510	COG1119	ATPase activity
AL522_RS10515	COG3585	molybdate ion transport
AL522_RS10515	COG2005	Transcriptional regulator
AL522_RS10525	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL522_RS10530	COG4149	molybdate abc transporter
AL522_RS10540	COG0561	phosphatase activity
AL522_RS10545	COG2706	6-phosphogluconolactonase activity
AL522_RS10555	COG1881	PFAM PEBP family protein
AL522_RS10565	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AL522_RS10575	COG2226	methyltransferase
AL522_RS10580	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL522_RS10590	COG0556	nucleotide-excision repair
AL522_RS10605	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL522_RS10610	COG0315	cyclic pyranopterin monophosphate synthase activity
AL522_RS10615	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL522_RS10620	COG0314	molybdopterin synthase activity
AL522_RS10635	COG0670	Belongs to the BI1 family
AL522_RS10640	COG0392	lysyltransferase activity
AL522_RS10645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL522_RS10650	COG3568	Endonuclease Exonuclease Phosphatase
AL522_RS10660	COG0513	Belongs to the DEAD box helicase family
AL522_RS10665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL522_RS10670	COG0477	Major facilitator Superfamily
AL522_RS10675	COG0306	phosphate transporter
AL522_RS10680	COG1376	ErfK ybiS ycfS ynhG family protein
AL522_RS10685	COG3387	PFAM Glycoside hydrolase 15-related
AL522_RS10690	COG0586	Pfam SNARE associated Golgi protein
AL522_RS10700	COG1686	Belongs to the peptidase S11 family
AL522_RS10705	COG3264	Mechanosensitive ion channel
AL522_RS10705	COG1511	domain protein
AL522_RS10720	COG0277	FAD linked oxidase domain protein
AL522_RS10725	COG1472	Belongs to the glycosyl hydrolase 3 family
AL522_RS10755	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AL522_RS10760	COG0477	Major facilitator Superfamily
AL522_RS10765	COG1732	Glycine betaine
AL522_RS10770	COG1174	glycine betaine transport
AL522_RS10775	COG1125	glycine betaine transport
AL522_RS10780	COG1174	glycine betaine transport
AL522_RS10785	COG0789	Transcriptional regulator
AL522_RS10805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL522_RS10810	COG1473	amidohydrolase
AL522_RS10815	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL522_RS10820	COG2986	histidine ammonia-lyase
AL522_RS10835	COG0402	S-adenosylhomocysteine deaminase activity
AL522_RS10840	COG1228	amidohydrolase
AL522_RS10875	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AL522_RS10880	COG1126	abc transporter atp-binding protein
AL522_RS10885	COG0765	amino acid transport
AL522_RS10890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL522_RS10895	COG0783	Belongs to the Dps family
AL522_RS10905	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL522_RS10915	COG1321	iron dependent repressor
AL522_RS10920	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AL522_RS10925	COG1566	PFAM secretion protein HlyD family protein
AL522_RS10930	COG2814	Major facilitator Superfamily
AL522_RS10940	COG2916	Histone family protein nucleoid-structuring protein H-NS
AL522_RS10945	COG0488	(ABC) transporter
AL522_RS10955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL522_RS10960	COG0303	'Molybdopterin
AL522_RS10970	COG4172	Belongs to the ABC transporter superfamily
AL522_RS10980	COG0601	transmembrane transport
AL522_RS11010	COG2133	pyrroloquinoline quinone binding
AL522_RS11020	COG1686	Belongs to the peptidase S11 family
AL522_RS11025	COG0671	phosphoesterase, PA-phosphatase related
AL522_RS11050	COG0778	Nitroreductase
AL522_RS11065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL522_RS11070	COG3842	ATPase activity
AL522_RS11075	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL522_RS11080	COG1177	transmembrane transport
AL522_RS11090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL522_RS11095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL522_RS11100	COG4160	amino acid transport
AL522_RS11105	COG4215	(ABC) transporter
AL522_RS11110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL522_RS11115	COG1126	abc transporter atp-binding protein
AL522_RS11130	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL522_RS11135	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL522_RS11140	COG0028	Belongs to the TPP enzyme family
AL522_RS11145	COG2431	L-lysine efflux transmembrane transporter activity
AL522_RS11150	COG3593	DNA synthesis involved in DNA repair
AL522_RS11155	COG1278	Cold shock
AL522_RS11160	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL522_RS11165	COG0542	response to heat
AL522_RS11170	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL522_RS11175	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AL522_RS11180	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL522_RS11185	COG4988	ABC transporter
AL522_RS11190	COG0492	ferredoxin-NADP+ reductase activity
AL522_RS11200	COG3107	peptidoglycan biosynthetic process
AL522_RS11200	COG1674	ftsk spoiiie
AL522_RS11205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AL522_RS11210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL522_RS11215	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL522_RS11220	COG0477	Major facilitator Superfamily
AL522_RS11225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL522_RS11230	COG1882	Formate acetyltransferase
AL522_RS11235	COG2116	formate transmembrane transporter activity
AL522_RS11240	COG1944	ATP diphosphatase activity
AL522_RS11245	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL522_RS11255	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL522_RS11260	COG0539	negative regulation of cytoplasmic translation
AL522_RS11265	COG0776	regulation of translation
AL522_RS11270	COG2333	competence protein COMEC
AL522_RS11270	COG0658	competence protein
AL522_RS11280	COG1663	tetraacyldisaccharide 4'-kinase activity
AL522_RS11285	COG3214	Protein conserved in bacteria
AL522_RS11290	COG2835	tetraacyldisaccharide 4'-kinase activity
AL522_RS11295	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL522_RS11300	COG3173	Aminoglycoside phosphotransferase
AL522_RS11305	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL522_RS11310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL522_RS11315	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AL522_RS11320	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AL522_RS11330	COG2989	Protein conserved in bacteria
AL522_RS11335	COG3108	Peptidase M15
AL522_RS11340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL522_RS11355	COG0017	Asparaginyl-tRNA synthetase
AL522_RS11360	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL522_RS11365	COG0308	aminopeptidase N
AL522_RS11370	COG1116	anion transmembrane transporter activity
AL522_RS11375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL522_RS11380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL522_RS11385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL522_RS11390	COG0431	NADPH-dependent FMN reductase
AL522_RS11395	COG1216	Glycosyl transferase, family 2
AL522_RS11405	COG0167	dihydroorotate dehydrogenase activity
AL522_RS11415	COG0633	Ferredoxin
AL522_RS11415	COG3217	Mosc domain protein beta barrel domain protein
AL522_RS11420	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL522_RS11420	COG0116	Belongs to the methyltransferase superfamily
AL522_RS11425	COG0488	(ABC) transporter
AL522_RS11430	COG2995	paraquat-inducible protein a
AL522_RS11435	COG3008	intermembrane lipid transfer
AL522_RS11435	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL522_RS11440	COG3009	Protein conserved in bacteria
AL522_RS11445	COG3130	regulation of translation
AL522_RS11450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL522_RS11455	COG1067	ATP-dependent peptidase activity
AL522_RS11460	COG3120	sequence-specific DNA binding
AL522_RS11475	COG3070	regulator of competence-specific genes
AL522_RS11480	COG1289	transmembrane transporter activity
AL522_RS11485	COG3304	Inner membrane component domain
AL522_RS11490	COG0210	DNA helicase
AL522_RS11505	COG1832	CoA-binding protein
AL522_RS11515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL522_RS11525	COG2920	part of a sulfur-relay system
AL522_RS11530	COG0670	Belongs to the BI1 family
AL522_RS11550	COG1012	belongs to the aldehyde dehydrogenase family
AL522_RS11565	COG3729	General stress protein
AL522_RS11575	COG2233	PERMEase
AL522_RS11580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL522_RS11585	COG2267	carboxylic ester hydrolase activity
AL522_RS11605	COG1309	transcriptional regulator
AL522_RS11615	COG1113	amino acid transport
AL522_RS11625	COG2197	response regulator
AL522_RS11640	COG2197	response regulator
AL522_RS11650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL522_RS11690	COG3238	Protein conserved in bacteria
AL522_RS11695	COG1247	-acetyltransferase
AL522_RS11700	COG1396	sequence-specific DNA binding
AL522_RS11745	COG0659	secondary active sulfate transmembrane transporter activity
AL522_RS11755	COG0840	transmembrane signaling receptor activity
AL522_RS11815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL522_RS11820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL522_RS11835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL522_RS11840	COG0463	Glycosyl transferase, family 2
AL522_RS11865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL522_RS11875	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS11880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL522_RS11890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL522_RS11905	COG2943	transferase activity, transferring hexosyl groups
AL522_RS11910	COG5645	(Lipo)protein
AL522_RS11925	COG1560	Kdo2-lipid A biosynthetic process
AL522_RS11930	COG1054	Belongs to the UPF0176 family
AL522_RS11935	COG2353	YceI-like domain
AL522_RS11940	COG3038	cytochrome b561
AL522_RS11965	COG0418	dihydroorotase activity
AL522_RS11975	COG2999	glutathione oxidoreductase activity
AL522_RS11980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL522_RS11995	COG0728	peptidoglycan biosynthetic process
AL522_RS12015	COG1815	bacterial-type flagellum-dependent cell motility
AL522_RS12020	COG1558	bacterial-type flagellum-dependent cell motility
AL522_RS12025	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL522_RS12030	COG1749	Flagellar hook protein flgE
AL522_RS12055	COG3951	Flagellar rod assembly protein muramidase FlgJ
AL522_RS12055	COG1705	Flagellar rod assembly protein muramidase FlgJ
AL522_RS12065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL522_RS12070	COG1530	ribonuclease E activity
AL522_RS12070	COG1530	ribonuclease E activity
AL522_RS12075	COG0564	pseudouridine synthase activity
AL522_RS12080	COG0424	maF-like protein
AL522_RS12085	COG1399	metal-binding, possibly nucleic acid-binding protein
AL522_RS12090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AL522_RS12095	COG0416	fatty acid biosynthetic process
AL522_RS12100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL522_RS12120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL522_RS12125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL522_RS12130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL522_RS12135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL522_RS12140	COG0470	DNA polymerase III
AL522_RS12145	COG0084	hydrolase, TatD family'
AL522_RS12150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL522_RS12150	COG1263	PTS System
AL522_RS12155	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AL522_RS12165	COG0537	adenosine 5'-monophosphoramidase activity
AL522_RS12170	COG5633	Lipoprotein
AL522_RS12175	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AL522_RS12195	COG1252	NADH dehydrogenase
AL522_RS12205	COG3134	Outer membrane lipoprotein
AL522_RS12210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL522_RS12220	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL522_RS12230	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL522_RS12235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL522_RS12240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL522_RS12245	COG1177	transmembrane transport
AL522_RS12260	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL522_RS12265	COG2850	peptidyl-arginine hydroxylation
AL522_RS12270	COG2205	protein histidine kinase activity
AL522_RS12275	COG0745	RESPONSE REGULATOR receiver
AL522_RS12280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL522_RS12285	COG2915	High frequency lysogenization protein hflD homolog
AL522_RS12300	COG1187	pseudouridine synthase activity
AL522_RS12305	COG0538	isocitrate dehydrogenase activity
AL522_RS12355	COG0840	transmembrane signaling receptor activity
AL522_RS12395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL522_RS12435	COG3386	PFAM SMP-30 Gluconolaconase
AL522_RS12460	COG0538	isocitrate dehydrogenase activity
AL522_RS12485	COG0859	PFAM glycosyl transferase family 9
AL522_RS12525	COG0454	-acetyltransferase
AL522_RS12535	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL522_RS12545	COG2390	Transcriptional regulator
AL522_RS12550	COG3959	Transketolase, thiamine diphosphate binding domain
AL522_RS12565	COG0668	transmembrane transport
AL522_RS12570	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AL522_RS12575	COG2261	transglycosylase associated protein
AL522_RS12580	COG4774	siderophore transport
AL522_RS12595	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AL522_RS12610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AL522_RS12615	COG3381	protein complex oligomerization
AL522_RS12620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL522_RS12625	COG0697	spore germination
AL522_RS12630	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL522_RS12630	COG0519	Catalyzes the synthesis of GMP from XMP
AL522_RS12770	COG0515	serine threonine protein kinase
AL522_RS12785	COG3209	COG3209 Rhs family protein
AL522_RS12785	COG4104	PAAR repeat-containing protein
AL522_RS12795	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AL522_RS12850	COG4948	Mandelate Racemase Muconate Lactonizing
AL522_RS12855	COG4172	Belongs to the ABC transporter superfamily
AL522_RS12865	COG0601	transmembrane transport
AL522_RS12890	COG0583	DNA-binding transcription factor activity
AL522_RS12895	COG0012	GTP binding
AL522_RS12900	COG0193	aminoacyl-tRNA hydrolase activity
AL522_RS12910	COG3706	GGDEF domain
AL522_RS12915	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL522_RS12920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL522_RS12925	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AL522_RS12930	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL522_RS12935	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL522_RS12950	COG2912	Transglutaminase-like superfamily
AL522_RS12960	COG0387	Pfam Sodium calcium exchanger
AL522_RS12965	COG4572	Cation transport regulator
AL522_RS12970	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AL522_RS12975	COG0515	serine threonine protein kinase
AL522_RS13015	COG3707	response regulator
AL522_RS13020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL522_RS13030	COG1116	anion transmembrane transporter activity
AL522_RS13035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL522_RS13035	COG2146	nitrite reductase [NAD(P)H] activity
AL522_RS13040	COG0243	molybdopterin cofactor binding
AL522_RS13050	COG2337	Toxic component of a toxin-antitoxin (TA) module
AL522_RS13055	COG2336	PFAM SpoVT AbrB
AL522_RS13060	COG1349	DNA-binding transcription factor activity
AL522_RS13065	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS13070	COG1879	ABC-type sugar transport system periplasmic component
AL522_RS13080	COG1129	ABC transporter
AL522_RS13085	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL522_RS13090	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS13095	COG4932	domain protein
AL522_RS13110	COG1846	Transcriptional regulator
AL522_RS13125	COG5001	Diguanylate cyclase
AL522_RS13140	COG3138	arginine N-succinyltransferase
AL522_RS13145	COG1012	belongs to the aldehyde dehydrogenase family
AL522_RS13155	COG2988	succinylglutamate desuccinylase activity
AL522_RS13160	COG3678	ATP-independent chaperone mediated protein folding
AL522_RS13165	COG0322	excinuclease ABC activity
AL522_RS13175	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AL522_RS13180	COG2814	Major facilitator Superfamily
AL522_RS13190	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL522_RS13200	COG1823	symporter activity
AL522_RS13205	COG1988	membrane-bound metal-dependent
AL522_RS13210	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS13220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL522_RS13230	COG3001	Fructosamine kinase
AL522_RS13240	COG3137	Salt-induced outer membrane protein
AL522_RS13245	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL522_RS13255	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL522_RS13265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL522_RS13275	COG0776	regulation of translation
AL522_RS13285	COG0386	Belongs to the glutathione peroxidase family
AL522_RS13295	COG0791	NLP P60 protein
AL522_RS13305	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AL522_RS13310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL522_RS13315	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL522_RS13320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL522_RS13320	COG0574	Belongs to the PEP-utilizing enzyme family
AL522_RS13330	COG0628	permease
AL522_RS13335	COG0277	FAD linked oxidase domain protein
AL522_RS13335	COG0247	lactate metabolic process
AL522_RS13345	COG0316	Belongs to the HesB IscA family
AL522_RS13350	COG0719	Fe-S assembly protein
AL522_RS13355	COG0396	ATPase activity
AL522_RS13360	COG0719	Fe-S assembly protein
AL522_RS13370	COG2166	iron-sulfur cluster assembly
AL522_RS13375	COG1376	ErfK ybiS ycfS ynhG family protein
AL522_RS13375	COG1388	LysM domain
AL522_RS13410	COG0307	riboflavin synthase, alpha
AL522_RS13420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL522_RS13425	COG2814	Major facilitator Superfamily
AL522_RS13430	COG0583	DNA-binding transcription factor activity
AL522_RS13435	COG1609	Transcriptional regulator
AL522_RS13445	COG0791	NLP P60 protein
AL522_RS13450	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL522_RS13460	COG0346	lactoylglutathione lyase activity
AL522_RS13465	COG1902	pentaerythritol trinitrate reductase activity
AL522_RS13470	COG1309	transcriptional regulator
AL522_RS13475	COG3313	Fe-S protein
AL522_RS13480	COG4989	oxidoreductase activity
AL522_RS13500	COG1566	PFAM secretion protein HlyD family protein
AL522_RS13515	COG3133	Outer membrane lipoprotein
AL522_RS13520	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL522_RS13530	COG2200	EAL domain
AL522_RS13550	COG1309	transcriptional regulator
AL522_RS13560	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS13585	COG0668	transmembrane transport
AL522_RS13595	COG0753	catalase activity
AL522_RS13600	COG3443	Belongs to the bacterial solute-binding protein 9 family
AL522_RS13605	COG2315	Protein conserved in bacteria
AL522_RS13615	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS13620	COG3546	catalase activity
AL522_RS13640	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL522_RS13690	COG3895	Periplasmic Protein
AL522_RS13700	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL522_RS13710	COG0625	glutathione transferase activity
AL522_RS13720	COG0504	CTP synthase activity
AL522_RS13725	COG4948	Mandelate Racemase Muconate Lactonizing
AL522_RS13740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL522_RS13745	COG4660	Part of a membrane complex involved in electron transport
AL522_RS13750	COG4659	FMN binding
AL522_RS13755	COG4658	electron transport chain
AL522_RS13760	COG4656	Part of a membrane complex involved in electron transport
AL522_RS13765	COG2878	Part of a membrane complex involved in electron transport
AL522_RS13770	COG4657	Part of a membrane complex involved in electron transport
AL522_RS13790	COG1879	ABC-type sugar transport system periplasmic component
AL522_RS13795	COG1129	ABC transporter
AL522_RS13800	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL522_RS13805	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL522_RS13815	COG2160	L-arabinose isomerase activity
AL522_RS13820	COG1069	ribulokinase activity
AL522_RS13825	COG1879	ABC-type sugar transport system periplasmic component
AL522_RS13835	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL522_RS13845	COG0673	inositol 2-dehydrogenase activity
AL522_RS13850	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL522_RS13855	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL522_RS13860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL522_RS13860	COG1263	PTS System
AL522_RS13865	COG1609	Transcriptional regulator
AL522_RS13870	COG5339	Protein conserved in bacteria
AL522_RS13875	COG1482	cell wall glycoprotein biosynthetic process
AL522_RS13880	COG0114	fumarate hydratase activity
AL522_RS13920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL522_RS13955	COG3135	benzoate transporter
AL522_RS13960	COG1396	sequence-specific DNA binding
AL522_RS13970	COG1335	isochorismatase
AL522_RS13975	COG4772	TonB-dependent receptor
AL522_RS13980	COG2084	Dehydrogenase
AL522_RS13990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL522_RS14030	COG2353	YceI-like domain
AL522_RS14035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL522_RS14040	COG0205	6-phosphofructokinase activity
AL522_RS14075	COG3011	Protein conserved in bacteria
AL522_RS14100	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS14110	COG1971	Probably functions as a manganese efflux pump
AL522_RS14135	COG0640	Transcriptional regulator
AL522_RS14180	COG0444	Belongs to the ABC transporter superfamily
AL522_RS14190	COG0601	transmembrane transport
AL522_RS14195	COG0747	negative chemotaxis
AL522_RS14200	COG4948	Mandelate Racemase Muconate Lactonizing
AL522_RS14235	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL522_RS14255	COG2130	NADP-dependent
AL522_RS14260	COG0346	lactoylglutathione lyase activity
AL522_RS14270	COG1349	DNA-binding transcription factor activity
AL522_RS14280	COG1902	pentaerythritol trinitrate reductase activity
AL522_RS14295	COG2351	hydroxyisourate hydrolase activity
AL522_RS14305	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AL522_RS14325	COG3121	Chaperone
AL522_RS14330	COG3188	usher protein
AL522_RS14365	COG3550	peptidyl-serine autophosphorylation
AL522_RS14370	COG1396	sequence-specific DNA binding
AL522_RS14390	COG1840	ABC-type Fe3 transport system, periplasmic component
AL522_RS14395	COG1609	Transcriptional regulator
AL522_RS14400	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS14405	COG3387	PFAM Glycoside hydrolase 15-related
AL522_RS14410	COG5654	RES domain protein
AL522_RS14415	COG5642	Protein of unknown function (DUF2384)
AL522_RS14435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL522_RS14440	COG0339	signal peptide processing
AL522_RS14450	COG2080	2 iron, 2 sulfur cluster binding
AL522_RS14450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL522_RS14460	COG0402	S-adenosylhomocysteine deaminase activity
AL522_RS14465	COG4221	oxidoreductase activity
AL522_RS14470	COG1742	UPF0060 membrane protein
AL522_RS14485	COG0477	Major facilitator Superfamily
AL522_RS14515	COG2233	PERMEase
AL522_RS14525	COG1940	carbohydrate kinase activity
AL522_RS14530	COG0583	DNA-binding transcription factor activity
AL522_RS14535	COG2814	Major facilitator Superfamily
AL522_RS14545	COG3038	cytochrome b561
AL522_RS14550	COG2814	Major facilitator Superfamily
AL522_RS14565	COG1309	transcriptional regulator
AL522_RS14615	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL522_RS14620	COG1012	belongs to the aldehyde dehydrogenase family
AL522_RS14640	COG0583	DNA-binding transcription factor activity
AL522_RS14645	COG0747	negative chemotaxis
AL522_RS14650	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL522_RS14660	COG0436	Aminotransferase
AL522_RS14670	COG0840	transmembrane signaling receptor activity
AL522_RS14680	COG5383	Protein conserved in bacteria
AL522_RS14690	COG0583	DNA-binding transcription factor activity
AL522_RS14695	COG2840	Smr protein MutS2
AL522_RS14700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL522_RS14710	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL522_RS14715	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL522_RS14725	COG0531	amino acid
AL522_RS14735	COG0745	RESPONSE REGULATOR receiver
AL522_RS14740	COG2205	protein histidine kinase activity
AL522_RS14745	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL522_RS14755	COG3591	Belongs to the peptidase S1B family
AL522_RS14760	COG1643	Atp-dependent helicase
AL522_RS14780	COG2911	Protein conserved in bacteria
AL522_RS14785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL522_RS14795	COG1285	pathogenesis
AL522_RS14815	COG4166	transmembrane transport
AL522_RS14820	COG2866	Carboxypeptidase
AL522_RS14825	COG4948	Mandelate Racemase Muconate Lactonizing
AL522_RS14830	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AL522_RS14840	COG2246	polysaccharide biosynthetic process
AL522_RS14855	COG3768	UPF0283 membrane protein
AL522_RS14860	COG3106	COG3106 Predicted ATPase
AL522_RS14870	COG1983	PspC domain protein
AL522_RS14880	COG1842	Phage shock protein A
AL522_RS14885	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL522_RS14895	COG0477	Major facilitator Superfamily
AL522_RS14905	COG4166	transmembrane transport
AL522_RS14935	COG4171	peptide transport system, permease
AL522_RS14945	COG4172	Belongs to the ABC transporter superfamily
AL522_RS14950	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL522_RS14955	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL522_RS14955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL522_RS14970	COG0840	transmembrane signaling receptor activity
AL522_RS14975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL522_RS14975	COG1263	PTS System
AL522_RS14985	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AL522_RS14990	COG1966	Carbon starvation protein
AL522_RS14995	COG2879	small protein
AL522_RS15000	COG5001	Diguanylate cyclase
AL522_RS15005	COG1024	Enoyl-CoA hydratase
AL522_RS15030	COG0023	Translation Initiation Factor
AL522_RS15035	COG0284	orotidine-5'-phosphate decarboxylase activity
AL522_RS15040	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL522_RS15045	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AL522_RS15050	COG0671	phosphoesterase, PA-phosphatase related
AL522_RS15060	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL522_RS15090	COG0616	signal peptide processing
AL522_RS15095	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS15115	COG0009	L-threonylcarbamoyladenylate synthase
AL522_RS15120	COG0613	PHP domain protein
AL522_RS15130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL522_RS15130	COG0512	Glutamine amidotransferase of anthranilate synthase
AL522_RS15135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL522_RS15145	COG0133	tryptophan synthase activity
AL522_RS15160	COG3047	cAMP biosynthetic process
AL522_RS15165	COG0727	PFAM Uncharacterised protein family (UPF0153)
AL522_RS15175	COG2917	probably involved in intracellular septation
AL522_RS15190	COG2350	Protein conserved in bacteria
AL522_RS15210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL522_RS15215	COG3099	Belongs to the UPF0263 family
AL522_RS15225	COG0444	Belongs to the ABC transporter superfamily
AL522_RS15230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL522_RS15235	COG0601	transmembrane transport
AL522_RS15245	COG4166	transmembrane transport
AL522_RS15250	COG2095	MarC family integral membrane protein
AL522_RS15255	COG1454	alcohol dehydrogenase
AL522_RS15255	COG1012	belongs to the aldehyde dehydrogenase family
AL522_RS15265	COG2916	Histone family protein nucleoid-structuring protein H-NS
AL522_RS15280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL522_RS15285	COG0745	RESPONSE REGULATOR receiver
AL522_RS15290	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL522_RS15295	COG3012	SEC-C Motif Domain Protein
AL522_RS15300	COG0788	formyltetrahydrofolate deformylase activity
AL522_RS15325	COG0708	Exodeoxyribonuclease III
AL522_RS15340	COG0778	Nitroreductase
AL522_RS15345	COG0616	signal peptide processing
AL522_RS15350	COG0252	asparaginase activity
AL522_RS15355	COG1335	isochorismatase
AL522_RS15360	COG3139	Protein of unknown function (DUF1315)
AL522_RS15365	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL522_RS15380	COG0656	L-ascorbic acid biosynthetic process
AL522_RS15385	COG3713	MltA-interacting MipA family protein
AL522_RS15390	COG2766	serine protein kinase
AL522_RS15395	COG2718	Belongs to the UPF0229 family
AL522_RS15420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL522_RS15425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL522_RS15430	COG2719	SpoVR family
AL522_RS15450	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL522_RS15460	COG0850	regulation of cytokinetic process
AL522_RS15465	COG2894	cell division
AL522_RS15470	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL522_RS15475	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AL522_RS15480	COG0318	PFAM AMP-dependent synthetase and ligase
AL522_RS15485	COG3065	identical protein binding
AL522_RS15495	COG1199	ATP-dependent helicase activity
AL522_RS15510	COG0251	oxidation-reduction process
AL522_RS15515	COG3140	Belongs to the UPF0181 family
AL522_RS15530	COG1760	l-serine dehydratase
AL522_RS15535	COG2200	EAL domain
AL522_RS15540	COG1253	flavin adenine dinucleotide binding
AL522_RS15545	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL522_RS15545	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL522_RS15550	COG3715	PTS system
AL522_RS15555	COG3716	PTS system mannose fructose sorbose family IID component
AL522_RS15565	COG2226	methyltransferase
AL522_RS15595	COG1414	Transcriptional regulator
AL522_RS15600	COG2814	Major facilitator Superfamily
AL522_RS15605	COG0501	Belongs to the peptidase M48B family
AL522_RS15615	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AL522_RS15620	COG1956	GAF domain-containing protein
AL522_RS15625	COG2995	paraquat-inducible protein a
AL522_RS15630	COG3008	intermembrane lipid transfer
AL522_RS15635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL522_RS15635	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AL522_RS15645	COG3813	Protein conserved in bacteria
AL522_RS15650	COG0477	Major facilitator Superfamily
AL522_RS15655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL522_RS15685	COG2755	lipolytic protein G-D-S-L family
AL522_RS15685	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL522_RS15700	COG1064	alcohol dehydrogenase
AL522_RS15745	COG4974	Belongs to the 'phage' integrase family
AL522_RS15755	COG1276	copper resistance
AL522_RS15760	COG2372	response to copper ion
AL522_RS15770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL522_RS15775	COG1770	oligopeptidase
AL522_RS15780	COG2979	Protein of unknown function (DUF533)
AL522_RS15790	COG0800	Aldolase
AL522_RS15795	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL522_RS15800	COG1737	Transcriptional regulator
AL522_RS15805	COG0469	pyruvate kinase activity
AL522_RS15815	COG1560	Kdo2-lipid A biosynthetic process
AL522_RS15820	COG0739	heme binding
AL522_RS15825	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AL522_RS15835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL522_RS15840	COG2255	four-way junction helicase activity
AL522_RS15845	COG0632	four-way junction helicase activity
AL522_RS15855	COG0217	transcriptional regulatory protein
AL522_RS15860	COG0494	nUDIX hydrolase
AL522_RS15870	COG1801	Protein of unknown function DUF72
AL522_RS15875	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AL522_RS15880	COG2226	methyltransferase
AL522_RS15885	COG0500	methyltransferase
AL522_RS15905	COG3142	Participates in the control of copper homeostasis
AL522_RS15910	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL522_RS15915	COG3102	Protein conserved in bacteria
AL522_RS15925	COG0583	DNA-binding transcription factor activity
AL522_RS15930	COG0667	Aldo Keto reductase
AL522_RS15945	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL522_RS15955	COG0745	RESPONSE REGULATOR receiver
AL522_RS15965	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL522_RS15970	COG0840	transmembrane signaling receptor activity
AL522_RS15975	COG0840	transmembrane signaling receptor activity
AL522_RS15985	COG0835	chemotaxis
AL522_RS16020	COG1877	trehalose-phosphatase activity
AL522_RS16030	COG0745	RESPONSE REGULATOR receiver
AL522_RS16045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL522_RS16060	COG1702	phosphate starvation-inducible protein PhoH
AL522_RS16070	COG2822	iron ion transport
AL522_RS16080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL522_RS16085	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL522_RS16085	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL522_RS16085	COG0506	proline dehydrogenase activity
AL522_RS16090	COG4763	Acyl-transferase
AL522_RS16095	COG1126	abc transporter atp-binding protein
AL522_RS16100	COG0765	amino acid transport
AL522_RS16105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL522_RS16135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL522_RS16140	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL522_RS16145	COG1516	flagellar protein fliS
AL522_RS16155	COG0366	Alpha amylase catalytic
AL522_RS16220	COG1677	Flagellar hook-basal body complex protein FliE
AL522_RS16225	COG1766	The M ring may be actively involved in energy transduction
AL522_RS16230	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL522_RS16235	COG1317	bacterial-type flagellum organization
AL522_RS16245	COG2882	bacterial-type flagellum organization
AL522_RS16255	COG1580	Controls the rotational direction of flagella during chemotaxis
AL522_RS16265	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL522_RS16275	COG1338	Plays a role in the flagellum-specific transport system
AL522_RS16280	COG1987	bacterial-type flagellum assembly
AL522_RS16295	COG0840	transmembrane signaling receptor activity
AL522_RS16320	COG1215	transferase activity, transferring glycosyl groups
AL522_RS16325	COG5475	Uncharacterized small protein (DUF2158)
AL522_RS16330	COG2354	Protein conserved in bacteria
AL522_RS16340	COG3727	T/G mismatch-specific endonuclease activity
AL522_RS16345	COG0270	DNA (cytosine-5-)-methyltransferase activity
AL522_RS16355	COG1418	mRNA catabolic process
AL522_RS16390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL522_RS16425	COG2261	transglycosylase associated protein
AL522_RS16465	COG5444	nuclease activity
AL522_RS16485	COG2706	6-phosphogluconolactonase activity
AL522_RS16490	COG0534	Mate efflux family protein
AL522_RS16495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL522_RS16510	COG2252	PERMEase
AL522_RS16540	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL522_RS16545	COG1129	ABC transporter
AL522_RS16555	COG3639	organic phosphonate transmembrane transporter activity
AL522_RS16565	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AL522_RS16575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AL522_RS16580	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AL522_RS16585	COG3454	Phosphonate metabolism
AL522_RS16590	COG4778	phosphonate C-P lyase system protein PhnL
AL522_RS16595	COG4107	phosphonate C-P lyase system protein PhnK
AL522_RS16600	COG3627	carbon phosphorus lyase activity
AL522_RS16605	COG3626	phosphonate metabolism
AL522_RS16610	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AL522_RS16615	COG3624	Phosphonate C-P lyase system protein PhnG
AL522_RS16620	COG2188	Transcriptional regulator
AL522_RS16630	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL522_RS16700	COG0300	oxidoreductase activity
AL522_RS16705	COG0028	Belongs to the TPP enzyme family
AL522_RS16725	COG1522	sequence-specific DNA binding
AL522_RS16735	COG1473	amidohydrolase
AL522_RS16740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL522_RS16755	COG4172	Belongs to the ABC transporter superfamily
AL522_RS16760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL522_RS16765	COG0601	transmembrane transport
AL522_RS16775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL522_RS16785	COG1012	belongs to the aldehyde dehydrogenase family
AL522_RS16790	COG1012	belongs to the aldehyde dehydrogenase family
AL522_RS16795	COG0583	DNA-binding transcription factor activity
AL522_RS16810	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL522_RS16815	COG1129	ABC transporter
AL522_RS16845	COG4773	Receptor
AL522_RS16870	COG0456	acetyltransferase
AL522_RS16890	COG0840	transmembrane signaling receptor activity
AL522_RS16905	COG3122	Protein conserved in bacteria
AL522_RS16910	COG1309	transcriptional regulator
AL522_RS16915	COG0277	FAD linked oxidase domain protein
AL522_RS16920	COG1442	glycosyl transferase family 8
AL522_RS16920	COG1216	Glycosyl transferase, family 2
AL522_RS16925	COG0673	inositol 2-dehydrogenase activity
AL522_RS16955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL522_RS16970	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL522_RS16975	COG1609	Transcriptional regulator
AL522_RS16980	COG2926	Belongs to the UPF0265 family
AL522_RS16985	COG1289	transmembrane transporter activity
AL522_RS17000	COG2925	Exonuclease
AL522_RS17005	COG2610	gluconate transmembrane transporter activity
AL522_RS17010	COG3622	Belongs to the hyi family
AL522_RS17015	COG0235	Class ii aldolase
AL522_RS17020	COG3395	kinase activity
AL522_RS17025	COG2084	Dehydrogenase
AL522_RS17030	COG1349	DNA-binding transcription factor activity
AL522_RS17035	COG0531	amino acid
AL522_RS17040	COG0174	glutamine synthetase
AL522_RS17045	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AL522_RS17050	COG1396	sequence-specific DNA binding
AL522_RS17050	COG1917	Cupin 2, conserved barrel domain protein
AL522_RS17055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL522_RS17060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL522_RS17070	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL522_RS17075	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL522_RS17080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL522_RS17090	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL522_RS17095	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL522_RS17105	COG0140	phosphoribosyl-ATP diphosphatase activity
AL522_RS17105	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL522_RS17110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL522_RS17125	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL522_RS17145	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AL522_RS17215	COG0463	Glycosyl transferase, family 2
AL522_RS17255	COG2982	Protein involved in outer membrane biogenesis
AL522_RS17260	COG0717	Belongs to the dCTP deaminase family
AL522_RS17265	COG0572	uridine kinase
AL522_RS17275	COG3447	MASE1 domain protein
AL522_RS17275	COG5001	Diguanylate cyclase
AL522_RS17275	COG5002	protein histidine kinase activity
AL522_RS17280	COG0443	Heat shock 70 kDa protein
AL522_RS17290	COG0667	Aldo Keto reductase
AL522_RS17295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL522_RS17305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL522_RS17315	COG2205	protein histidine kinase activity
AL522_RS17320	COG0745	RESPONSE REGULATOR receiver
AL522_RS17325	COG0826	peptidase U32
AL522_RS17340	COG4948	Mandelate Racemase Muconate Lactonizing
AL522_RS17345	COG1063	alcohol dehydrogenase
AL522_RS17350	COG2271	Major facilitator Superfamily
AL522_RS17355	COG0246	Mannitol dehydrogenase
AL522_RS17360	COG1802	Transcriptional regulator
AL522_RS17365	COG0351	phosphomethylpyrimidine kinase
AL522_RS17370	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AL522_RS17405	COG3634	alkyl hydroperoxide reductase activity
AL522_RS17420	COG0489	protein tyrosine kinase activity
AL522_RS17425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL522_RS17425	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL522_RS17430	COG1380	Effector of murein hydrolase LrgA
AL522_RS17435	COG1346	cytolysis
AL522_RS17440	COG0295	cytidine deaminase activity
AL522_RS17445	COG0281	malic enzyme
AL522_RS17450	COG2949	membrane
AL522_RS17460	COG1129	ABC transporter
AL522_RS17475	COG2311	Membrane
AL522_RS17485	COG0477	Major facilitator Superfamily
AL522_RS17490	COG0583	DNA-binding transcription factor activity
AL522_RS17505	COG1120	ATPase activity
AL522_RS17510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL522_RS17515	COG0833	amino acid
AL522_RS17520	COG0583	DNA-binding transcription factor activity
AL522_RS17530	COG2855	membrane
AL522_RS17535	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AL522_RS17545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL522_RS17545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL522_RS17545	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL522_RS17550	COG1105	Belongs to the carbohydrate kinase PfkB family
AL522_RS17555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL522_RS17555	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL522_RS17565	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL522_RS17570	COG0523	cobalamin synthesis protein
AL522_RS17575	COG0671	phosphoesterase, PA-phosphatase related
AL522_RS17585	COG0791	NLP P60 protein
AL522_RS17590	COG2200	EAL domain
AL522_RS17595	COG4166	transmembrane transport
AL522_RS17600	COG4174	ABC transporter (Permease)
AL522_RS17605	COG4239	(ABC) transporter, permease
AL522_RS17610	COG4172	Belongs to the ABC transporter superfamily
AL522_RS17620	COG2814	Major facilitator Superfamily
AL522_RS17630	COG1061	Type III restriction enzyme res subunit
AL522_RS17635	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL522_RS17645	COG3082	Protein of unknown function (DUF1414)
AL522_RS17660	COG0582	viral genome integration into host DNA
AL522_RS17735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL522_RS17800	COG3311	Transcriptional regulator
AL522_RS17825	COG4615	Cyclic peptide transporter
AL522_RS17830	COG3145	DNA-N1-methyladenine dioxygenase activity
AL522_RS17855	COG1132	(ABC) transporter
AL522_RS17880	COG2223	nitrite transmembrane transporter activity
AL522_RS17885	COG2198	Histidine kinase
AL522_RS17885	COG0642	Histidine kinase
AL522_RS17890	COG2197	response regulator
AL522_RS17905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL522_RS17910	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL522_RS17920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL522_RS17930	COG4575	ribosome binding
AL522_RS17940	COG2153	protein acetylation
AL522_RS17945	COG1007	ATP synthesis coupled electron transport
AL522_RS17950	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL522_RS17955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL522_RS17960	COG0713	ATP synthesis coupled electron transport
AL522_RS17965	COG0839	Belongs to the complex I subunit 6 family
AL522_RS17975	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AL522_RS17985	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AL522_RS17995	COG0649	NAD binding
AL522_RS17995	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL522_RS18010	COG0583	DNA-binding transcription factor activity
AL522_RS18015	COG0436	Aminotransferase
AL522_RS18020	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AL522_RS18025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL522_RS18030	COG3013	Belongs to the UPF0304 family
AL522_RS18035	COG3092	negative regulation of chromosome organization
AL522_RS18040	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL522_RS18045	COG0857	belongs to the CobB CobQ family
AL522_RS18045	COG0280	phosphate acetyltransferase
AL522_RS18050	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AL522_RS18055	COG0625	glutathione transferase activity
AL522_RS18060	COG1090	epimerase
AL522_RS18065	COG4598	ABC transporter
AL522_RS18070	COG4160	amino acid transport
AL522_RS18085	COG0163	prenyltransferase activity
AL522_RS18090	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL522_RS18095	COG1286	toxin biosynthetic process
AL522_RS18105	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AL522_RS18110	COG0285	dihydrofolate synthase activity
AL522_RS18120	COG0586	Pfam SNARE associated Golgi protein
AL522_RS18130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL522_RS18140	COG2207	Transcriptional regulator
AL522_RS18155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL522_RS18165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL522_RS18180	COG3101	peptidyl-lysine hydroxylation
AL522_RS18185	COG0730	response to heat
AL522_RS18195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL522_RS18210	COG2062	phosphohistidine phosphatase, SixA
AL522_RS18215	COG1024	Enoyl-CoA hydratase
AL522_RS18215	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL522_RS18220	COG0183	Belongs to the thiolase family
AL522_RS18225	COG3691	Protein conserved in bacteria
AL522_RS18230	COG2067	long-chain fatty acid transport protein
AL522_RS18240	COG4235	cytochrome complex assembly
AL522_RS18240	COG3088	subunit of a heme lyase
AL522_RS18245	COG3088	subunit of a heme lyase
AL522_RS18245	COG4235	cytochrome complex assembly
AL522_RS18255	COG1138	Cytochrome C-type biogenesis protein
AL522_RS18260	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL522_RS18265	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL522_RS18270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL522_RS18275	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL522_RS18285	COG2116	formate transmembrane transporter activity
AL522_RS18325	COG1388	LysM domain
AL522_RS18325	COG3584	3D domain protein
AL522_RS18360	COG2223	nitrite transmembrane transporter activity
AL522_RS18405	COG0436	Aminotransferase
AL522_RS18415	COG3275	phosphorelay sensor kinase activity
AL522_RS18420	COG3279	Response regulator of the LytR AlgR family
AL522_RS18425	COG0837	glucose binding
AL522_RS18430	COG3961	Belongs to the TPP enzyme family
AL522_RS18435	COG0667	Aldo Keto reductase
AL522_RS18445	COG1914	H( )-stimulated, divalent metal cation uptake system
AL522_RS18450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL522_RS18465	COG2116	formate transmembrane transporter activity
AL522_RS18470	COG3415	Transposase
AL522_RS18475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL522_RS18510	COG0583	DNA-binding transcription factor activity
AL522_RS18515	COG0385	Bile acid
AL522_RS18520	COG3530	Putative quorum-sensing-regulated virulence factor
AL522_RS18530	COG3115	cell septum assembly
AL522_RS18535	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AL522_RS18555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL522_RS18565	COG2205	protein histidine kinase activity
AL522_RS18570	COG0745	RESPONSE REGULATOR receiver
AL522_RS18575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL522_RS18580	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AL522_RS18585	COG4208	sulfate ABC transporter
AL522_RS18590	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AL522_RS18610	COG0456	acetyltransferase
AL522_RS18625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL522_RS18630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL522_RS18635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AL522_RS18640	COG5342	invasion associated locus B
AL522_RS18645	COG0494	nUDIX hydrolase
AL522_RS18660	COG3850	Histidine kinase
AL522_RS18665	COG2197	response regulator
AL522_RS18670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL522_RS18675	COG1393	Belongs to the ArsC family
AL522_RS18680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL522_RS18690	COG0400	carboxylic ester hydrolase activity
AL522_RS18695	COG1444	tRNA N-acetyltransferase activity
AL522_RS18700	COG2321	neutral zinc metallopeptidase
AL522_RS18705	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL522_RS18710	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL522_RS18715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL522_RS18720	COG2716	regulation of RNA biosynthetic process
AL522_RS18725	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL522_RS18730	COG3706	GGDEF domain
AL522_RS18745	COG4783	chaperone-mediated protein folding
AL522_RS18750	COG1393	Belongs to the ArsC family
AL522_RS18755	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL522_RS18760	COG2233	PERMEase
AL522_RS18770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL522_RS18775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL522_RS18780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL522_RS18790	COG0573	inorganic phosphate transmembrane transporter activity
AL522_RS18805	COG0500	methyltransferase
AL522_RS18815	COG2239	Acts as a magnesium transporter
AL522_RS18845	COG0517	IMP dehydrogenase activity
AL522_RS18845	COG0516	GMP reductase activity
AL522_RS18850	COG1570	exodeoxyribonuclease VII activity
AL522_RS18865	COG4993	Dehydrogenase
AL522_RS18870	COG1645	bacterial-type flagellum-dependent swarming motility
AL522_RS18875	COG1160	GTP binding
AL522_RS18880	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL522_RS18885	COG2976	Protein conserved in bacteria
AL522_RS18890	COG0124	histidyl-tRNA synthetase
AL522_RS18900	COG1426	Protein conserved in bacteria
AL522_RS18910	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL522_RS18915	COG0105	UTP biosynthetic process
AL522_RS18920	COG4953	penicillin-binding protein 1C
AL522_RS18925	COG2373	Large extracellular alpha-helical protein
AL522_RS18930	COG2897	thiosulfate sulfurtransferase activity
AL522_RS18940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL522_RS18950	COG1959	2 iron, 2 sulfur cluster binding
AL522_RS18960	COG0483	inositol monophosphate 1-phosphatase activity
AL522_RS18970	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AL522_RS18980	COG3711	transcriptional antiterminator
AL522_RS18985	COG2814	Major facilitator Superfamily
AL522_RS18990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL522_RS18995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL522_RS18995	COG1017	nitric oxide dioxygenase activity
AL522_RS19000	COG0347	Belongs to the P(II) protein family
AL522_RS19005	COG2204	response regulator
AL522_RS19010	COG3170	Tfp pilus assembly protein FimV
AL522_RS19015	COG2205	protein histidine kinase activity
AL522_RS19020	COG0047	phosphoribosylformylglycinamidine synthase activity
AL522_RS19020	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL522_RS19025	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL522_RS19035	COG0560	Phosphoserine phosphatase
AL522_RS19040	COG1737	Transcriptional regulator
AL522_RS19045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL522_RS19050	COG0736	holo-[acyl-carrier-protein] synthase activity
AL522_RS19055	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL522_RS19070	COG0571	ribonuclease III activity
AL522_RS19080	COG0481	GTPase activity
AL522_RS19085	COG3086	response to oxidative stress
AL522_RS19090	COG3026	antisigma factor binding
AL522_RS19105	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL522_RS19110	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AL522_RS19115	COG0513	Belongs to the DEAD box helicase family
AL522_RS19125	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
AL522_RS19130	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL522_RS19135	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL522_RS19140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL522_RS19145	COG0497	DNA recombination
AL522_RS19150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL522_RS19155	COG2914	Belongs to the UPF0125 (RnfH) family
AL522_RS19160	COG2867	negative regulation of translational initiation
AL522_RS19165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL522_RS19175	COG0582	viral genome integration into host DNA
AL522_RS19235	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AL522_RS19285	COG0673	inositol 2-dehydrogenase activity
AL522_RS19305	COG0673	inositol 2-dehydrogenase activity
AL522_RS19320	COG1012	belongs to the aldehyde dehydrogenase family
AL522_RS19330	COG3962	Belongs to the TPP enzyme family
AL522_RS19340	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS19360	COG2308	Evidence 4 Homologs of previously reported genes of
AL522_RS19370	COG1305	Transglutaminase-like
AL522_RS19385	COG1278	Cold shock
AL522_RS19400	COG0747	negative chemotaxis
AL522_RS19405	COG0601	transmembrane transport
AL522_RS19410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL522_RS19415	COG0444	Belongs to the ABC transporter superfamily
AL522_RS19425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL522_RS19435	COG2040	homocysteine
AL522_RS19440	COG0833	amino acid
AL522_RS19450	COG4575	ribosome binding
AL522_RS19460	COG1780	Probably involved in ribonucleotide reductase function
AL522_RS19465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL522_RS19490	COG2814	Major facilitator Superfamily
AL522_RS19495	COG1846	Transcriptional regulator
AL522_RS19500	COG1566	PFAM secretion protein HlyD family protein
AL522_RS19505	COG2814	Major facilitator Superfamily
AL522_RS19510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL522_RS19515	COG3118	belongs to the thioredoxin family
AL522_RS19520	COG3148	PFAM DTW domain containing protein
AL522_RS19525	COG0045	succinate-CoA ligase (ADP-forming) activity
AL522_RS19525	COG1042	CoA-binding domain protein
AL522_RS19525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL522_RS19530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL522_RS19540	COG0477	Major facilitator Superfamily
AL522_RS19570	COG0542	response to heat
AL522_RS19580	COG0564	pseudouridine synthase activity
AL522_RS19585	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL522_RS19590	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL522_RS19595	COG1605	Chorismate mutase
AL522_RS19595	COG0077	Prephenate dehydratase
AL522_RS19600	COG1605	Chorismate mutase
AL522_RS19600	COG0287	Prephenate dehydrogenase
AL522_RS19605	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL522_RS19615	COG0335	large ribosomal subunit rRNA binding
AL522_RS19630	COG0228	four-way junction DNA binding
AL522_RS19635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL522_RS19640	COG4137	Cytochrome C assembly protein
AL522_RS19645	COG4536	flavin adenine dinucleotide binding
AL522_RS19650	COG1854	S-ribosylhomocysteine lyase activity
AL522_RS19660	COG2918	glutathione biosynthetic process
AL522_RS19665	COG1238	metal cluster binding
AL522_RS19670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL522_RS19695	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AL522_RS19710	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL522_RS19725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL522_RS19730	COG2824	Alkylphosphonate utilization operon protein PhnA
AL522_RS19735	COG2951	lytic endotransglycosylase activity
AL522_RS19740	COG2181	nitrate reductase activity
AL522_RS19745	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL522_RS19750	COG1140	nitrate reductase beta subunit
AL522_RS19755	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL522_RS19760	COG2223	nitrite transmembrane transporter activity
AL522_RS19765	COG2197	response regulator
AL522_RS19770	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL522_RS19775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL522_RS19780	COG1388	LysM domain
AL522_RS19780	COG4942	peptidase
AL522_RS19785	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL522_RS19790	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL522_RS19795	COG0585	pseudouridine synthase activity
AL522_RS19805	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL522_RS19810	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AL522_RS19825	COG2895	sulfate adenylyltransferase (ATP) activity
AL522_RS19830	COG0175	sulfate reduction
AL522_RS19835	COG1648	precorrin-2 dehydrogenase activity
AL522_RS19835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL522_RS19840	COG2234	aminopeptidase activity
AL522_RS19855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL522_RS19860	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL522_RS19865	COG0720	synthase
AL522_RS19870	COG0602	queuosine metabolic process
AL522_RS19875	COG0148	phosphopyruvate hydratase activity
AL522_RS19880	COG0504	CTP synthase activity
AL522_RS19885	COG3956	TIGRFAM MazG family protein
AL522_RS19890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL522_RS19895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL522_RS19905	COG1929	Belongs to the glycerate kinase type-1 family
AL522_RS19910	COG2084	Dehydrogenase
AL522_RS19920	COG4948	Mandelate Racemase Muconate Lactonizing
AL522_RS19925	COG4948	Mandelate Racemase Muconate Lactonizing
AL522_RS19930	COG2271	Major facilitator Superfamily
AL522_RS19935	COG2721	sulfolactate sulfo-lyase activity
AL522_RS19940	COG0697	spore germination
AL522_RS19955	COG1984	allophanate hydrolase subunit 2
AL522_RS19960	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL522_RS19965	COG0436	Aminotransferase
AL522_RS19980	COG4221	oxidoreductase activity
AL522_RS19985	COG0765	amino acid transport
AL522_RS19990	COG0765	amino acid transport
AL522_RS20000	COG0716	FMN binding
AL522_RS20005	COG0564	pseudouridine synthase activity
AL522_RS20010	COG3098	single-species biofilm formation
AL522_RS20020	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL522_RS20020	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL522_RS20025	COG1611	Belongs to the LOG family
AL522_RS20035	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AL522_RS20040	COG2363	Small membrane protein
AL522_RS20045	COG0583	DNA-binding transcription factor activity
AL522_RS20055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL522_RS20060	COG2166	iron-sulfur cluster assembly
AL522_RS20065	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL522_RS20070	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL522_RS20090	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL522_RS20095	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL522_RS20095	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL522_RS20100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL522_RS20105	COG1074	ATP-dependent DNA helicase activity
AL522_RS20115	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL522_RS20130	COG4795	General secretion pathway protein
AL522_RS20140	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL522_RS20145	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AL522_RS20155	COG1051	belongs to the nudix hydrolase family
AL522_RS20165	COG3066	DNA modification
AL522_RS20170	COG0861	Integral membrane protein TerC family
AL522_RS20180	COG0667	Aldo Keto reductase
AL522_RS20195	COG0583	DNA-binding transcription factor activity
AL522_RS20200	COG2814	Major facilitator Superfamily
AL522_RS20215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AL522_RS20225	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL522_RS20230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL522_RS20235	COG4974	Belongs to the 'phage' integrase family
AL522_RS20240	COG0716	FMN binding
AL522_RS20250	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL522_RS20260	COG1272	protein, Hemolysin III
AL522_RS20265	COG1737	Transcriptional regulator
AL522_RS20270	COG2723	6-phospho-beta-galactosidase activity
AL522_RS20275	COG1028	Short-chain dehydrogenase reductase Sdr
AL522_RS20280	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL522_RS20280	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL522_RS20295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL522_RS20300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL522_RS20305	COG0006	proline dipeptidase activity
AL522_RS20315	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AL522_RS20325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL522_RS20330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL522_RS20340	COG0583	DNA-binding transcription factor activity
AL522_RS20345	COG2968	Membrane
AL522_RS20350	COG1279	arginine transmembrane transporter activity
AL522_RS20355	COG0668	transmembrane transport
AL522_RS20360	COG0191	fructose-bisphosphate aldolase activity
AL522_RS20365	COG0126	phosphoglycerate kinase activity
AL522_RS20370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL522_RS20375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL522_RS20380	COG0501	Belongs to the peptidase M48B family
AL522_RS20385	COG3753	Protein conserved in bacteria
AL522_RS20395	COG1166	arginine decarboxylase activity
AL522_RS20405	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL522_RS20410	COG2814	Major facilitator Superfamily
AL522_RS20430	COG2356	endonuclease I
AL522_RS20435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL522_RS20445	COG1678	Uncharacterized ACR, COG1678
AL522_RS20455	COG2805	Type II/IV secretion system protein
AL522_RS20460	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL522_RS20465	COG0762	integral membrane protein
AL522_RS20470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL522_RS20475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL522_RS20485	COG3171	Protein conserved in bacteria
AL522_RS20495	COG1194	a g-specific adenine glycosylase
AL522_RS20505	COG0741	lytic transglycosylase activity
AL522_RS20510	COG1982	Orn Lys Arg decarboxylase major
AL522_RS20515	COG0604	alcohol dehydrogenase
AL522_RS20520	COG1546	Belongs to the CinA family
AL522_RS20525	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL522_RS20530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL522_RS20535	COG4558	Periplasmic binding protein
AL522_RS20540	COG3720	iron ion transport
AL522_RS20555	COG1695	Transcriptional regulator
AL522_RS20560	COG2375	cellular response to nickel ion
AL522_RS20575	COG3708	Transcriptional regulator
AL522_RS20575	COG2207	Transcriptional regulator
AL522_RS20585	COG1294	oxidase, subunit
AL522_RS20590	COG1271	oxidase subunit
AL522_RS20595	COG1733	regulation of RNA biosynthetic process
AL522_RS20600	COG0702	epimerase
AL522_RS20610	COG3685	Protein conserved in bacteria
AL522_RS20615	COG3685	Protein conserved in bacteria
AL522_RS20620	COG3729	General stress protein
AL522_RS20625	COG2199	diguanylate cyclase activity
AL522_RS20650	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AL522_RS20655	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AL522_RS20665	COG0084	hydrolase, TatD family'
AL522_RS20670	COG4667	esterase of the alpha-beta hydrolase superfamily
AL522_RS20680	COG2823	Periplasmic or secreted lipoprotein
AL522_RS20685	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL522_RS20690	COG1473	amidohydrolase
AL522_RS20695	COG0700	Nucleoside recognition
AL522_RS20700	COG3366	ferrous iron transmembrane transporter activity
AL522_RS20705	COG1528	Iron-storage protein
AL522_RS20720	COG2271	Major facilitator Superfamily
AL522_RS20730	COG1609	Transcriptional regulator
AL522_RS20735	COG5001	Diguanylate cyclase
AL522_RS20735	COG3300	MHYT domain
AL522_RS20740	COG4297	protein containing double-stranded beta helix domain
AL522_RS20750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL522_RS20795	COG0848	biopolymer transport protein
AL522_RS20805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL522_RS20830	COG2207	Transcriptional regulator
AL522_RS20835	COG0656	L-ascorbic acid biosynthetic process
AL522_RS20840	COG2132	Multicopper oxidase
AL522_RS20850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AL522_RS20860	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL522_RS20865	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL522_RS20870	COG0583	DNA-binding transcription factor activity
AL522_RS20875	COG0187	DNA topoisomerase II activity
AL522_RS20880	COG3150	esterase
AL522_RS20885	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL522_RS20890	COG3151	Protein conserved in bacteria
AL522_RS20895	COG0494	nUDIX hydrolase
AL522_RS20905	COG5463	Belongs to the UPF0441 family
AL522_RS20910	COG0754	glutathionylspermidine amidase activity
AL522_RS20915	COG3384	dioxygenase
AL522_RS20925	COG2960	long-chain fatty acid transporting porin activity
AL522_RS20940	COG3025	triphosphatase activity
AL522_RS20945	COG4991	sh3 domain protein
AL522_RS20950	COG0617	tRNA 3'-terminal CCA addition
AL522_RS20955	COG1968	undecaprenyl-diphosphatase activity
AL522_RS20960	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL522_RS20975	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL522_RS20980	COG0358	DNA primase activity
AL522_RS20995	COG3663	DNA glycosylase
AL522_RS21055	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AL522_RS21155	COG4695	Portal protein
AL522_RS21240	COG4974	Belongs to the 'phage' integrase family
AL522_RS21250	COG3550	peptidyl-serine autophosphorylation
AL522_RS21260	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL522_RS21265	COG2199	diguanylate cyclase activity
AL522_RS21270	COG0659	secondary active sulfate transmembrane transporter activity
AL522_RS21275	COG0288	reversible hydration of carbon dioxide
AL522_RS21280	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AL522_RS21290	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL522_RS21290	COG1902	pentaerythritol trinitrate reductase activity
AL522_RS21295	COG2813	Specifically methylates the guanine in position
AL522_RS21300	COG1451	nucleotide metabolic process
AL522_RS21305	COG0038	chloride channel
AL522_RS21310	COG0673	inositol 2-dehydrogenase activity
AL522_RS21320	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AL522_RS21325	COG2721	sulfolactate sulfo-lyase activity
AL522_RS21340	COG2271	Major facilitator Superfamily
AL522_RS21350	COG0586	Pfam SNARE associated Golgi protein
AL522_RS21360	COG1422	Protein of unknown function (DUF1090)
AL522_RS21365	COG4575	ribosome binding
AL522_RS21370	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AL522_RS21380	COG2259	Doxx family
AL522_RS21385	COG0435	Glutathione S-transferase
AL522_RS21395	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL522_RS21400	COG3107	peptidoglycan biosynthetic process
AL522_RS21405	COG0792	nuclease activity
AL522_RS21415	COG2823	Periplasmic or secreted lipoprotein
AL522_RS21420	COG1741	Belongs to the pirin family
AL522_RS21425	COG0583	DNA-binding transcription factor activity
AL522_RS21430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL522_RS21430	COG3711	transcriptional antiterminator
AL522_RS21445	COG3964	amidohydrolase
AL522_RS21480	COG0312	modulator of DNA gyrase
AL522_RS21485	COG3028	Belongs to the UPF0307 family
AL522_RS21495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL522_RS21500	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL522_RS21505	COG0840	transmembrane signaling receptor activity
AL522_RS21515	COG2707	UPF0756 membrane protein
AL522_RS21525	COG2105	PFAM AIG2 family protein
AL522_RS21535	COG0729	surface antigen
AL522_RS21540	COG1253	flavin adenine dinucleotide binding
AL522_RS21550	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL522_RS21565	COG0545	Peptidyl-prolyl cis-trans isomerase
AL522_RS21570	COG3061	Opacity-associated protein A
AL522_RS21580	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL522_RS21585	COG2965	DNA replication, synthesis of RNA primer
AL522_RS21590	COG0360	Binds together with S18 to 16S ribosomal RNA
AL522_RS21600	COG1073	alpha beta
AL522_RS21605	COG0840	transmembrane signaling receptor activity
AL522_RS21615	COG1960	acyl-CoA dehydrogenase activity
AL522_RS21620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL522_RS21625	COG0557	exoribonuclease II activity
AL522_RS21635	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL522_RS21640	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AL522_RS21645	COG0330	HflC and HflK could
AL522_RS21650	COG0330	HflC and HflK could
AL522_RS21655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL522_RS21665	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL522_RS21670	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL522_RS21675	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL522_RS21680	COG0802	atpase or kinase
AL522_RS21685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL522_RS21685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL522_RS21690	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL522_RS21710	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL522_RS21715	COG1162	GTPase activity
AL522_RS21720	COG0688	phosphatidylethanolamine metabolic process
AL522_RS21725	COG3264	Mechanosensitive ion channel
AL522_RS21725	COG1511	domain protein
AL522_RS21730	COG0039	L-malate dehydrogenase activity
AL522_RS21735	COG1438	arginine binding
AL522_RS21755	COG2732	(Barnase) inhibitor
AL522_RS21765	COG1289	transmembrane transporter activity
AL522_RS21770	COG1566	PFAM secretion protein HlyD family protein
AL522_RS21780	COG0583	DNA-binding transcription factor activity
AL522_RS21785	COG0312	modulator of DNA gyrase
AL522_RS21790	COG3164	Protein of unknown function
AL522_RS21795	COG1530	ribonuclease E activity
AL522_RS21805	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL522_RS21810	COG1792	Involved in formation and maintenance of cell shape
AL522_RS21815	COG1077	Cell shape determining protein MreB Mrl
AL522_RS21820	COG2200	EAL domain
AL522_RS21820	COG2199	diguanylate cyclase activity
AL522_RS21825	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL522_RS21830	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AL522_RS21835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL522_RS21840	COG0511	ligase activity, forming carbon-carbon bonds
AL522_RS21845	COG0439	Biotin carboxylase
AL522_RS21850	COG3924	membrane
AL522_RS21855	COG4145	pantothenate transmembrane transporter activity
AL522_RS21860	COG2264	protein methyltransferase activity
AL522_RS21870	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AL522_RS21875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL522_RS21880	COG4597	amino acid ABC transporter
AL522_RS21885	COG0765	amino acid transport
AL522_RS21890	COG1126	abc transporter atp-binding protein
AL522_RS21930	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL522_RS21950	COG0551	DNA topoisomerase type I activity
AL522_RS21960	COG0758	DNA mediated transformation
AL522_RS21965	COG0242	peptide deformylase activity
AL522_RS21970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL522_RS21975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL522_RS21975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL522_RS21980	COG0569	domain protein
AL522_RS21985	COG1970	mechanosensitive ion channel activity
AL522_RS21990	COG3036	rescue of stalled ribosome
AL522_RS21995	COG0789	Transcriptional regulator
AL522_RS22005	COG0203	ribosomal protein L17
AL522_RS22010	COG0202	RNA polymerase activity
AL522_RS22015	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL522_RS22020	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL522_RS22025	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL522_RS22030	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL522_RS22035	COG0201	protein transport
AL522_RS22040	COG0200	Binds to the 23S rRNA
AL522_RS22045	COG1841	ribosomal large subunit assembly
AL522_RS22050	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AL522_RS22055	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AL522_RS22065	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL522_RS22070	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL522_RS22085	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AL522_RS22105	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL522_RS22120	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL522_RS22125	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL522_RS22135	COG0088	Forms part of the polypeptide exit tunnel
AL522_RS22145	COG0051	transcription antitermination factor activity, RNA binding
AL522_RS22150	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AL522_RS22170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL522_RS22180	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AL522_RS22185	COG2168	tRNA wobble position uridine thiolation
AL522_RS22200	COG2964	Protein conserved in bacteria
AL522_RS22205	COG0545	Peptidyl-prolyl cis-trans isomerase
AL522_RS22210	COG2900	Belongs to the SlyX family
AL522_RS22215	COG1047	Peptidyl-prolyl cis-trans
AL522_RS22220	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AL522_RS22225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL522_RS22225	COG0475	glutathione-regulated potassium exporter activity
AL522_RS22230	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL522_RS22235	COG0488	(ABC) transporter
AL522_RS22240	COG2175	clavaminate synthase activity
AL522_RS22245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL522_RS22250	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL522_RS22255	COG4521	taurine ABC transporter
AL522_RS22270	COG0429	hydrolase of the alpha beta-hydrolase fold
AL522_RS22280	COG3954	Phosphoribulokinase
AL522_RS22285	COG1765	OsmC-like protein
AL522_RS22295	COG1289	transmembrane transporter activity
AL522_RS22300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL522_RS22310	COG2184	nucleotidyltransferase activity
AL522_RS22320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL522_RS22325	COG0738	Major facilitator superfamily
AL522_RS22330	COG0402	S-adenosylhomocysteine deaminase activity
AL522_RS22335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL522_RS22355	COG0546	phosphoglycolate phosphatase activity
AL522_RS22360	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL522_RS22370	COG3266	domain, Protein
AL522_RS22375	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL522_RS22380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL522_RS22390	COG4796	Type ii and iii secretion system protein
AL522_RS22415	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL522_RS22420	COG0494	nUDIX hydrolase
AL522_RS22430	COG1011	Hydrolase
AL522_RS22435	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL522_RS22440	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL522_RS22445	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AL522_RS22465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL522_RS22470	COG2183	response to ionizing radiation
AL522_RS22475	COG0366	Alpha amylase catalytic
AL522_RS22485	COG2267	carboxylic ester hydrolase activity
AL522_RS22490	COG1040	competence protein
AL522_RS22495	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AL522_RS22495	COG0316	Belongs to the HesB IscA family
AL522_RS22500	COG1640	4-alpha-glucanotransferase
AL522_RS22505	COG0058	SHG alpha-glucan phosphorylase activity
AL522_RS22510	COG1349	DNA-binding transcription factor activity
AL522_RS22520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL522_RS22530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL522_RS22560	COG0679	Auxin Efflux Carrier
AL522_RS22570	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL522_RS22580	COG0058	SHG alpha-glucan phosphorylase activity
AL522_RS22585	COG0297	glycogen (starch) synthase activity
AL522_RS22595	COG1523	belongs to the glycosyl hydrolase 13 family
AL522_RS22610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL522_RS22615	COG2095	MarC family integral membrane protein
AL522_RS22630	COG2610	gluconate transmembrane transporter activity
AL522_RS22635	COG3265	gluconokinase activity
AL522_RS22640	COG1609	Transcriptional regulator
AL522_RS22645	COG1741	Belongs to the pirin family
AL522_RS22655	COG1247	-acetyltransferase
AL522_RS22670	COG0405	Gamma-glutamyltransferase
AL522_RS22680	COG0584	glycerophosphoryl diester phosphodiesterase
AL522_RS22690	COG0395	ABC-type sugar transport system, permease component
AL522_RS22695	COG1175	transmembrane transport
AL522_RS22720	COG4177	L-phenylalanine transmembrane transporter activity
AL522_RS22740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL522_RS22745	COG2177	Part of the ABC transporter FtsEX involved in
AL522_RS22750	COG2884	Cell division ATP-binding protein ftsE
AL522_RS22755	COG0552	protein localization to endoplasmic reticulum
AL522_RS22755	COG0552	protein localization to endoplasmic reticulum
AL522_RS22760	COG0742	ribosomal rna small subunit methyltransferase
AL522_RS22765	COG3776	membrane
AL522_RS22775	COG3714	YhhN family
AL522_RS22780	COG2217	Heavy metal translocating P-type atpase
AL522_RS22785	COG0425	Belongs to the sulfur carrier protein TusA family
AL522_RS22790	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL522_RS22800	COG1082	Xylose isomerase domain protein TIM barrel
AL522_RS22805	COG0673	inositol 2-dehydrogenase activity
AL522_RS22810	COG3962	Belongs to the TPP enzyme family
AL522_RS22815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL522_RS22825	COG3718	enzyme involved in inositol metabolism
AL522_RS22840	COG0477	Major facilitator Superfamily
AL522_RS22845	COG0628	permease
AL522_RS22855	COG1312	Catalyzes the dehydration of D-mannonate
AL522_RS22860	COG2200	EAL domain
AL522_RS22870	COG0113	porphobilinogen synthase activity
AL522_RS22875	COG2199	diguanylate cyclase activity
AL522_RS22880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL522_RS22890	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL522_RS22895	COG2814	Major facilitator Superfamily
AL522_RS22920	COG0667	Aldo Keto reductase
AL522_RS22925	COG2081	HI0933 family
AL522_RS22930	COG0306	phosphate transporter
AL522_RS22945	COG0742	ribosomal rna small subunit methyltransferase
AL522_RS22960	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL522_RS22975	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL522_RS22985	COG1234	tRNA 3'-trailer cleavage
AL522_RS22990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL522_RS23010	COG2814	Major facilitator Superfamily
AL522_RS23015	COG0583	DNA-binding transcription factor activity
AL522_RS23020	COG2862	Uncharacterized protein family, UPF0114
AL522_RS23025	COG2205	protein histidine kinase activity
AL522_RS23030	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AL522_RS23035	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AL522_RS23040	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane