locus-tag	class	description
FOB88_RS00025	COG4565	transcriptional regulatory protein
FOB88_RS00030	COG3290	protein histidine kinase activity
FOB88_RS00045	COG4628	conserved protein (DUF2132)
FOB88_RS00055	COG0076	glutamate decarboxylase activity
FOB88_RS00060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB88_RS00140	COG2203	Gaf domain
FOB88_RS00140	COG3706	GGDEF domain
FOB88_RS00140	COG4251	negative regulation of phosphorylation
FOB88_RS00140	COG5001	Diguanylate cyclase
FOB88_RS00145	COG0778	Nitroreductase
FOB88_RS00150	COG1280	lysine exporter protein (LysE YggA)
FOB88_RS00155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB88_RS00165	COG0697	spore germination
FOB88_RS00175	COG3842	ATPase activity
FOB88_RS00180	COG1653	transport
FOB88_RS00185	COG1175	transmembrane transport
FOB88_RS00200	COG0583	DNA-binding transcription factor activity
FOB88_RS00205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB88_RS00225	COG4232	protein-disulfide reductase activity
FOB88_RS00230	COG1794	racemase activity, acting on amino acids and derivatives
FOB88_RS00265	COG1116	anion transmembrane transporter activity
FOB88_RS00280	COG0439	Biotin carboxylase
FOB88_RS00300	COG1126	abc transporter atp-binding protein
FOB88_RS00305	COG0765	amino acid transport
FOB88_RS00310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB88_RS00325	COG1082	Xylose isomerase domain protein TIM barrel
FOB88_RS00330	COG0673	inositol 2-dehydrogenase activity
FOB88_RS00340	COG1609	Transcriptional regulator
FOB88_RS00345	COG3300	MHYT domain
FOB88_RS00345	COG5001	Diguanylate cyclase
FOB88_RS00370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB88_RS00375	COG0601	transmembrane transport
FOB88_RS00385	COG4172	Belongs to the ABC transporter superfamily
FOB88_RS00390	COG4948	Mandelate Racemase Muconate Lactonizing
FOB88_RS00400	COG2233	PERMEase
FOB88_RS00405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB88_RS00410	COG0778	Nitroreductase
FOB88_RS00415	COG2267	carboxylic ester hydrolase activity
FOB88_RS00420	COG0251	oxidation-reduction process
FOB88_RS00425	COG1335	isochorismatase
FOB88_RS00430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB88_RS00435	COG1309	transcriptional regulator
FOB88_RS00450	COG5642	Protein of unknown function (DUF2384)
FOB88_RS00455	COG5654	RES domain protein
FOB88_RS00470	COG0431	NADPH-dependent FMN reductase
FOB88_RS00485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB88_RS00500	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOB88_RS00530	COG1605	Chorismate mutase
FOB88_RS00535	COG0840	transmembrane signaling receptor activity
FOB88_RS00540	COG2076	Multidrug Resistance protein
FOB88_RS00545	COG2076	Multidrug Resistance protein
FOB88_RS00550	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOB88_RS00555	COG0726	polysaccharide deacetylase
FOB88_RS00560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOB88_RS00560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB88_RS00595	COG0745	RESPONSE REGULATOR receiver
FOB88_RS00600	COG5000	phosphorelay sensor kinase activity
FOB88_RS00600	COG5002	protein histidine kinase activity
FOB88_RS00605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB88_RS00615	COG0840	transmembrane signaling receptor activity
FOB88_RS00650	COG0246	Mannitol dehydrogenase
FOB88_RS00700	COG1454	alcohol dehydrogenase
FOB88_RS00705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB88_RS00725	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS00820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOB88_RS00825	COG0840	transmembrane signaling receptor activity
FOB88_RS00835	COG3141	response to X-ray
FOB88_RS00850	COG4773	Receptor
FOB88_RS00855	COG2916	Histone family protein nucleoid-structuring protein H-NS
FOB88_RS00880	COG0024	Methionine aminopeptidase
FOB88_RS00885	COG3706	GGDEF domain
FOB88_RS00900	COG0561	phosphatase activity
FOB88_RS00910	COG1349	DNA-binding transcription factor activity
FOB88_RS00915	COG1609	Transcriptional regulator
FOB88_RS00920	COG1263	PTS System
FOB88_RS00920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB88_RS00925	COG2723	6-phospho-beta-galactosidase activity
FOB88_RS00930	COG5001	Diguanylate cyclase
FOB88_RS00940	COG1349	DNA-binding transcription factor activity
FOB88_RS00945	COG2200	EAL domain
FOB88_RS00950	COG1716	ATPase activity
FOB88_RS00950	COG5001	Diguanylate cyclase
FOB88_RS00965	COG1187	pseudouridine synthase activity
FOB88_RS00980	COG4774	siderophore transport
FOB88_RS00990	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FOB88_RS00990	COG3608	succinylglutamate desuccinylase aspartoacylase
FOB88_RS01000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FOB88_RS01005	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FOB88_RS01010	COG2080	2 iron, 2 sulfur cluster binding
FOB88_RS01015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB88_RS01020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB88_RS01025	COG1121	(ABC) transporter
FOB88_RS01095	COG1012	belongs to the aldehyde dehydrogenase family
FOB88_RS01100	COG0523	cobalamin synthesis protein
FOB88_RS01110	COG0601	transmembrane transport
FOB88_RS01115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB88_RS01120	COG0444	Belongs to the ABC transporter superfamily
FOB88_RS01130	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOB88_RS01150	COG2022	thiamine diphosphate biosynthetic process
FOB88_RS01155	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB88_RS01165	COG1280	lysine exporter protein (LysE YggA)
FOB88_RS01190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB88_RS01195	COG1064	alcohol dehydrogenase
FOB88_RS01230	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FOB88_RS01240	COG3182	Iron-regulated membrane protein
FOB88_RS01250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB88_RS01255	COG2066	Belongs to the glutaminase family
FOB88_RS01300	COG2134	cdp-diacylglycerol pyrophosphatase
FOB88_RS01360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB88_RS01360	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOB88_RS01385	COG0010	Belongs to the arginase family
FOB88_RS01410	COG3157	Type VI secretion system effector, Hcp
FOB88_RS01420	COG2135	peptidase activity
FOB88_RS01435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB88_RS01565	COG0583	DNA-binding transcription factor activity
FOB88_RS01580	COG1484	DNA-dependent DNA replication
FOB88_RS01590	COG4372	Transposase
FOB88_RS01595	COG3436	PFAM IS66 Orf2 family protein
FOB88_RS01860	COG1522	sequence-specific DNA binding
FOB88_RS01875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB88_RS01915	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOB88_RS02065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB88_RS02110	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOB88_RS02120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOB88_RS02130	COG4932	domain protein
FOB88_RS02130	COG1388	LysM domain
FOB88_RS02130	COG2373	Large extracellular alpha-helical protein
FOB88_RS02185	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOB88_RS02260	COG3550	peptidyl-serine autophosphorylation
FOB88_RS02320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB88_RS02335	COG4104	PAAR repeat-containing protein
FOB88_RS02415	COG0840	transmembrane signaling receptor activity
FOB88_RS02465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB88_RS02485	COG1192	Involved in chromosome partitioning
FOB88_RS02520	COG0431	NADPH-dependent FMN reductase
FOB88_RS02525	COG1393	Belongs to the ArsC family
FOB88_RS02530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOB88_RS02540	COG0456	acetyltransferase
FOB88_RS02545	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB88_RS02550	COG0523	cobalamin synthesis protein
FOB88_RS02555	COG2226	methyltransferase
FOB88_RS02560	COG2271	Major facilitator Superfamily
FOB88_RS02565	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOB88_RS02610	COG3344	reverse transcriptase
FOB88_RS02670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB88_RS02675	COG2181	nitrate reductase activity
FOB88_RS02680	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOB88_RS02685	COG1140	nitrate reductase beta subunit
FOB88_RS02690	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOB88_RS02695	COG2223	nitrite transmembrane transporter activity
FOB88_RS02705	COG2002	toxin-antitoxin pair type II binding
FOB88_RS02750	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOB88_RS02790	COG3657	addiction module killer protein
FOB88_RS02805	COG5290	Psort location Cytoplasmic, score
FOB88_RS02880	COG3626	phosphonate metabolism
FOB88_RS02885	COG3627	carbon phosphorus lyase activity
FOB88_RS02890	COG4107	phosphonate C-P lyase system protein PhnK
FOB88_RS02895	COG4778	phosphonate C-P lyase system protein PhnL
FOB88_RS02900	COG3454	Phosphonate metabolism
FOB88_RS02905	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FOB88_RS02910	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOB88_RS02920	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FOB88_RS02930	COG3639	organic phosphonate transmembrane transporter activity
FOB88_RS02935	COG4191	Histidine kinase
FOB88_RS02935	COG0784	Response regulator, receiver
FOB88_RS02940	COG1129	ABC transporter
FOB88_RS02945	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS02960	COG0191	fructose-bisphosphate aldolase activity
FOB88_RS02970	COG0745	RESPONSE REGULATOR receiver
FOB88_RS02975	COG2252	PERMEase
FOB88_RS02985	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB88_RS02990	COG0534	Mate efflux family protein
FOB88_RS03120	COG0515	serine threonine protein kinase
FOB88_RS03125	COG3501	Rhs element vgr protein
FOB88_RS03170	COG3501	Rhs element vgr protein
FOB88_RS03270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB88_RS03275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB88_RS03280	COG0383	alpha-mannosidase activity
FOB88_RS03285	COG3711	transcriptional antiterminator
FOB88_RS03295	COG0071	Belongs to the small heat shock protein (HSP20) family
FOB88_RS03305	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FOB88_RS03315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB88_RS03330	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FOB88_RS03365	COG1418	mRNA catabolic process
FOB88_RS03375	COG0840	transmembrane signaling receptor activity
FOB88_RS03380	COG0270	DNA (cytosine-5-)-methyltransferase activity
FOB88_RS03385	COG3727	T/G mismatch-specific endonuclease activity
FOB88_RS03395	COG2354	Protein conserved in bacteria
FOB88_RS03400	COG5475	Uncharacterized small protein (DUF2158)
FOB88_RS03405	COG1215	transferase activity, transferring glycosyl groups
FOB88_RS03430	COG0840	transmembrane signaling receptor activity
FOB88_RS03435	COG3385	transposase activity
FOB88_RS03455	COG1338	Plays a role in the flagellum-specific transport system
FOB88_RS03470	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOB88_RS03475	COG1580	Controls the rotational direction of flagella during chemotaxis
FOB88_RS03485	COG2882	bacterial-type flagellum organization
FOB88_RS03495	COG1317	bacterial-type flagellum organization
FOB88_RS03500	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOB88_RS03510	COG1677	Flagellar hook-basal body complex protein FliE
FOB88_RS03525	COG1368	sulfuric ester hydrolase activity
FOB88_RS03565	COG0366	Alpha amylase catalytic
FOB88_RS03605	COG0438	transferase activity, transferring glycosyl groups
FOB88_RS03605	COG1216	Glycosyl transferase, family 2
FOB88_RS03655	COG4763	Acyl-transferase
FOB88_RS03660	COG0494	nUDIX hydrolase
FOB88_RS03665	COG4763	Acyl-transferase
FOB88_RS03670	COG2181	nitrate reductase activity
FOB88_RS03675	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOB88_RS03675	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOB88_RS03675	COG0506	proline dehydrogenase activity
FOB88_RS03680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB88_RS03690	COG2822	iron ion transport
FOB88_RS03700	COG1702	phosphate starvation-inducible protein PhoH
FOB88_RS03710	COG0477	Major facilitator Superfamily
FOB88_RS03725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB88_RS03740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB88_RS03770	COG0582	viral genome integration into host DNA
FOB88_RS03780	COG4725	Belongs to the MT-A70-like family
FOB88_RS03855	COG0305	Participates in initiation and elongation during chromosome replication
FOB88_RS03865	COG0484	heat shock protein binding
FOB88_RS03880	COG3772	lysozyme
FOB88_RS03915	COG1783	phage Terminase large subunit
FOB88_RS04075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB88_RS04085	COG0745	RESPONSE REGULATOR receiver
FOB88_RS04090	COG1877	trehalose-phosphatase activity
FOB88_RS04125	COG0835	chemotaxis
FOB88_RS04130	COG0840	transmembrane signaling receptor activity
FOB88_RS04135	COG0840	transmembrane signaling receptor activity
FOB88_RS04140	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOB88_RS04150	COG0745	RESPONSE REGULATOR receiver
FOB88_RS04180	COG0018	arginyl-trna synthetase
FOB88_RS04185	COG3102	Protein conserved in bacteria
FOB88_RS04190	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOB88_RS04195	COG3142	Participates in the control of copper homeostasis
FOB88_RS04210	COG1280	lysine exporter protein (LysE YggA)
FOB88_RS04215	COG0500	methyltransferase
FOB88_RS04220	COG2226	methyltransferase
FOB88_RS04225	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FOB88_RS04230	COG1801	Protein of unknown function DUF72
FOB88_RS04240	COG0494	nUDIX hydrolase
FOB88_RS04245	COG0217	transcriptional regulatory protein
FOB88_RS04255	COG0632	four-way junction helicase activity
FOB88_RS04260	COG2255	four-way junction helicase activity
FOB88_RS04265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB88_RS04275	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FOB88_RS04280	COG0739	heme binding
FOB88_RS04285	COG1560	Kdo2-lipid A biosynthetic process
FOB88_RS04295	COG0469	pyruvate kinase activity
FOB88_RS04300	COG1737	Transcriptional regulator
FOB88_RS04305	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOB88_RS04310	COG0800	Aldolase
FOB88_RS04315	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FOB88_RS04320	COG2979	Protein of unknown function (DUF533)
FOB88_RS04325	COG1770	oligopeptidase
FOB88_RS04330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOB88_RS04340	COG2372	response to copper ion
FOB88_RS04345	COG1276	copper resistance
FOB88_RS04370	COG0840	transmembrane signaling receptor activity
FOB88_RS04385	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FOB88_RS04425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB88_RS04430	COG0477	Major facilitator Superfamily
FOB88_RS04435	COG3813	Protein conserved in bacteria
FOB88_RS04440	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FOB88_RS04440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB88_RS04445	COG3008	intermembrane lipid transfer
FOB88_RS04450	COG2995	paraquat-inducible protein a
FOB88_RS04455	COG1956	GAF domain-containing protein
FOB88_RS04460	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FOB88_RS04470	COG0501	Belongs to the peptidase M48B family
FOB88_RS04475	COG2814	Major facilitator Superfamily
FOB88_RS04510	COG2226	methyltransferase
FOB88_RS04520	COG3716	PTS system mannose fructose sorbose family IID component
FOB88_RS04525	COG3715	PTS system
FOB88_RS04530	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB88_RS04530	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB88_RS04535	COG1253	flavin adenine dinucleotide binding
FOB88_RS04540	COG2200	EAL domain
FOB88_RS04545	COG1760	l-serine dehydratase
FOB88_RS04555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOB88_RS04560	COG3140	Belongs to the UPF0181 family
FOB88_RS04565	COG0251	oxidation-reduction process
FOB88_RS04575	COG1199	ATP-dependent helicase activity
FOB88_RS04585	COG3065	identical protein binding
FOB88_RS04590	COG0318	PFAM AMP-dependent synthetase and ligase
FOB88_RS04595	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FOB88_RS04600	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FOB88_RS04605	COG2894	cell division
FOB88_RS04610	COG0850	regulation of cytokinetic process
FOB88_RS04620	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOB88_RS04635	COG2186	Transcriptional regulator
FOB88_RS04640	COG2719	SpoVR family
FOB88_RS04645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB88_RS04650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB88_RS04675	COG2718	Belongs to the UPF0229 family
FOB88_RS04680	COG2766	serine protein kinase
FOB88_RS04685	COG3713	MltA-interacting MipA family protein
FOB88_RS04690	COG0656	L-ascorbic acid biosynthetic process
FOB88_RS04705	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB88_RS04710	COG3139	Protein of unknown function (DUF1315)
FOB88_RS04715	COG1335	isochorismatase
FOB88_RS04720	COG0252	asparaginase activity
FOB88_RS04725	COG0616	signal peptide processing
FOB88_RS04730	COG0778	Nitroreductase
FOB88_RS04745	COG0708	Exodeoxyribonuclease III
FOB88_RS04770	COG0788	formyltetrahydrofolate deformylase activity
FOB88_RS04775	COG3012	SEC-C Motif Domain Protein
FOB88_RS04780	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOB88_RS04785	COG0745	RESPONSE REGULATOR receiver
FOB88_RS04790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOB88_RS04815	COG1012	belongs to the aldehyde dehydrogenase family
FOB88_RS04815	COG1454	alcohol dehydrogenase
FOB88_RS04820	COG2095	MarC family integral membrane protein
FOB88_RS04825	COG4166	transmembrane transport
FOB88_RS04835	COG0601	transmembrane transport
FOB88_RS04840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB88_RS04855	COG3099	Belongs to the UPF0263 family
FOB88_RS04860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB88_RS04875	COG2350	Protein conserved in bacteria
FOB88_RS04885	COG1607	acyl-coa hydrolase
FOB88_RS04890	COG2917	probably involved in intracellular septation
FOB88_RS04900	COG0727	PFAM Uncharacterised protein family (UPF0153)
FOB88_RS04915	COG0159	tryptophan synthase activity
FOB88_RS04920	COG0133	tryptophan synthase activity
FOB88_RS04930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOB88_RS04945	COG0613	PHP domain protein
FOB88_RS04950	COG0009	L-threonylcarbamoyladenylate synthase
FOB88_RS05050	COG1187	pseudouridine synthase activity
FOB88_RS05055	COG2851	Citrate transporter
FOB88_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS05070	COG0616	signal peptide processing
FOB88_RS05110	COG0671	phosphoesterase, PA-phosphatase related
FOB88_RS05115	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FOB88_RS05120	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FOB88_RS05125	COG0284	orotidine-5'-phosphate decarboxylase activity
FOB88_RS05130	COG0023	Translation Initiation Factor
FOB88_RS05140	COG0235	Class ii aldolase
FOB88_RS05145	COG1024	Enoyl-CoA hydratase
FOB88_RS05150	COG5001	Diguanylate cyclase
FOB88_RS05160	COG1966	Carbon starvation protein
FOB88_RS05165	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FOB88_RS05175	COG1263	PTS System
FOB88_RS05175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB88_RS05185	COG0583	DNA-binding transcription factor activity
FOB88_RS05190	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB88_RS05190	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB88_RS05195	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOB88_RS05200	COG4172	Belongs to the ABC transporter superfamily
FOB88_RS05205	COG4172	Belongs to the ABC transporter superfamily
FOB88_RS05215	COG4168	peptide transport system, permease
FOB88_RS05230	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOB88_RS05235	COG1842	Phage shock protein A
FOB88_RS05245	COG1983	PspC domain protein
FOB88_RS05255	COG3106	COG3106 Predicted ATPase
FOB88_RS05260	COG3768	UPF0283 membrane protein
FOB88_RS05270	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOB88_RS05275	COG4948	Mandelate Racemase Muconate Lactonizing
FOB88_RS05280	COG2866	Carboxypeptidase
FOB88_RS05285	COG4166	transmembrane transport
FOB88_RS05295	COG0037	tRNA processing
FOB88_RS05300	COG1285	pathogenesis
FOB88_RS05310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB88_RS05315	COG2911	Protein conserved in bacteria
FOB88_RS05325	COG3784	Protein of unknown function (DUF1318)
FOB88_RS05335	COG1643	Atp-dependent helicase
FOB88_RS05340	COG3591	Belongs to the peptidase S1B family
FOB88_RS05350	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOB88_RS05355	COG2205	protein histidine kinase activity
FOB88_RS05360	COG0745	RESPONSE REGULATOR receiver
FOB88_RS05370	COG0531	amino acid
FOB88_RS05380	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOB88_RS05385	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FOB88_RS05395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB88_RS05400	COG2840	Smr protein MutS2
FOB88_RS05405	COG0583	DNA-binding transcription factor activity
FOB88_RS05415	COG5383	Protein conserved in bacteria
FOB88_RS05430	COG0840	transmembrane signaling receptor activity
FOB88_RS05435	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB88_RS05440	COG0747	negative chemotaxis
FOB88_RS05445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOB88_RS05465	COG3038	cytochrome b561
FOB88_RS05475	COG2814	Major facilitator Superfamily
FOB88_RS05480	COG0583	DNA-binding transcription factor activity
FOB88_RS05485	COG1940	carbohydrate kinase activity
FOB88_RS05490	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOB88_RS05515	COG0477	Major facilitator Superfamily
FOB88_RS05535	COG4221	oxidoreductase activity
FOB88_RS05540	COG0402	S-adenosylhomocysteine deaminase activity
FOB88_RS05550	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FOB88_RS05560	COG0339	signal peptide processing
FOB88_RS05565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB88_RS05580	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS05595	COG2211	Major facilitator Superfamily
FOB88_RS05600	COG1472	Belongs to the glycosyl hydrolase 3 family
FOB88_RS05610	COG1396	sequence-specific DNA binding
FOB88_RS05615	COG3550	peptidyl-serine autophosphorylation
FOB88_RS05630	COG0840	transmembrane signaling receptor activity
FOB88_RS05645	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FOB88_RS05665	COG1012	belongs to the aldehyde dehydrogenase family
FOB88_RS05670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB88_RS05710	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS05720	COG0523	cobalamin synthesis protein
FOB88_RS05730	COG0494	nUDIX hydrolase
FOB88_RS05735	COG0791	NLP P60 protein
FOB88_RS05740	COG1285	pathogenesis
FOB88_RS05745	COG0243	molybdopterin cofactor binding
FOB88_RS05765	COG2223	nitrite transmembrane transporter activity
FOB88_RS05775	COG0058	SHG alpha-glucan phosphorylase activity
FOB88_RS05780	COG1640	4-alpha-glucanotransferase
FOB88_RS05815	COG1175	transmembrane transport
FOB88_RS05820	COG3833	ABC-type maltose transport systems, permease component
FOB88_RS05835	COG1785	Belongs to the alkaline phosphatase family
FOB88_RS05845	COG1902	pentaerythritol trinitrate reductase activity
FOB88_RS05855	COG0346	lactoylglutathione lyase activity
FOB88_RS05880	COG1393	Belongs to the ArsC family
FOB88_RS05885	COG1473	amidohydrolase
FOB88_RS05890	COG0700	Nucleoside recognition
FOB88_RS05895	COG3366	ferrous iron transmembrane transporter activity
FOB88_RS05905	COG4221	oxidoreductase activity
FOB88_RS05910	COG0583	DNA-binding transcription factor activity
FOB88_RS05925	COG0110	maltose O-acetyltransferase activity
FOB88_RS05940	COG2130	NADP-dependent
FOB88_RS05945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB88_RS05950	COG1737	Transcriptional regulator
FOB88_RS05955	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS05960	COG1129	ABC transporter
FOB88_RS05965	COG1879	ABC-type sugar transport system periplasmic component
FOB88_RS06030	COG0205	6-phosphofructokinase activity
FOB88_RS06035	COG2353	YceI-like domain
FOB88_RS06075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB88_RS06085	COG2084	Dehydrogenase
FOB88_RS06090	COG4772	TonB-dependent receptor
FOB88_RS06100	COG1335	isochorismatase
FOB88_RS06105	COG1396	sequence-specific DNA binding
FOB88_RS06110	COG3135	benzoate transporter
FOB88_RS06135	COG4290	ribonuclease
FOB88_RS06140	COG4977	sequence-specific DNA binding
FOB88_RS06145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB88_RS06180	COG1482	cell wall glycoprotein biosynthetic process
FOB88_RS06185	COG5339	Protein conserved in bacteria
FOB88_RS06190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOB88_RS06195	COG0673	inositol 2-dehydrogenase activity
FOB88_RS06205	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS06215	COG1879	ABC-type sugar transport system periplasmic component
FOB88_RS06220	COG1069	ribulokinase activity
FOB88_RS06225	COG2160	L-arabinose isomerase activity
FOB88_RS06245	COG0564	pseudouridine synthase activity
FOB88_RS06260	COG3122	Protein conserved in bacteria
FOB88_RS06265	COG1278	Cold shock
FOB88_RS06280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB88_RS06285	COG1522	sequence-specific DNA binding
FOB88_RS06300	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FOB88_RS06315	COG0668	transmembrane transport
FOB88_RS06330	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOB88_RS06335	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOB88_RS06380	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS06385	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS06390	COG1129	ABC transporter
FOB88_RS06395	COG1879	ABC-type sugar transport system periplasmic component
FOB88_RS06410	COG4657	Part of a membrane complex involved in electron transport
FOB88_RS06415	COG2878	Part of a membrane complex involved in electron transport
FOB88_RS06420	COG4656	Part of a membrane complex involved in electron transport
FOB88_RS06425	COG4658	electron transport chain
FOB88_RS06430	COG4659	FMN binding
FOB88_RS06435	COG4660	Part of a membrane complex involved in electron transport
FOB88_RS06440	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOB88_RS06445	COG0504	CTP synthase activity
FOB88_RS06455	COG0625	glutathione transferase activity
FOB88_RS06465	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOB88_RS06475	COG3895	Periplasmic Protein
FOB88_RS06480	COG2351	hydroxyisourate hydrolase activity
FOB88_RS06510	COG1309	transcriptional regulator
FOB88_RS06520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOB88_RS06560	COG4294	response to UV
FOB88_RS06565	COG3729	General stress protein
FOB88_RS06570	COG0753	catalase activity
FOB88_RS06575	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOB88_RS06590	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS06600	COG2200	EAL domain
FOB88_RS06610	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOB88_RS06615	COG3133	Outer membrane lipoprotein
FOB88_RS06620	COG1846	Transcriptional regulator
FOB88_RS06630	COG1566	PFAM secretion protein HlyD family protein
FOB88_RS06635	COG1289	transmembrane transporter activity
FOB88_RS06650	COG4989	oxidoreductase activity
FOB88_RS06655	COG3313	Fe-S protein
FOB88_RS06660	COG1309	transcriptional regulator
FOB88_RS06665	COG1902	pentaerythritol trinitrate reductase activity
FOB88_RS06670	COG0346	lactoylglutathione lyase activity
FOB88_RS06675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOB88_RS06680	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOB88_RS06685	COG0791	NLP P60 protein
FOB88_RS06695	COG1609	Transcriptional regulator
FOB88_RS06700	COG0583	DNA-binding transcription factor activity
FOB88_RS06705	COG2814	Major facilitator Superfamily
FOB88_RS06710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOB88_RS06715	COG0307	riboflavin synthase, alpha
FOB88_RS06750	COG1388	LysM domain
FOB88_RS06750	COG1376	ErfK ybiS ycfS ynhG family protein
FOB88_RS06755	COG2166	iron-sulfur cluster assembly
FOB88_RS06765	COG0719	Fe-S assembly protein
FOB88_RS06770	COG0396	ATPase activity
FOB88_RS06775	COG0719	Fe-S assembly protein
FOB88_RS06780	COG0316	Belongs to the HesB IscA family
FOB88_RS06790	COG0247	lactate metabolic process
FOB88_RS06790	COG0277	FAD linked oxidase domain protein
FOB88_RS06795	COG0628	permease
FOB88_RS06800	COG0574	Belongs to the PEP-utilizing enzyme family
FOB88_RS06800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB88_RS06805	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOB88_RS06810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB88_RS06815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FOB88_RS06825	COG0791	NLP P60 protein
FOB88_RS06835	COG0386	Belongs to the glutathione peroxidase family
FOB88_RS06845	COG0776	regulation of translation
FOB88_RS06850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB88_RS06850	COG0072	phenylalanine-tRNA ligase activity
FOB88_RS06870	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOB88_RS06880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOB88_RS06885	COG3137	Salt-induced outer membrane protein
FOB88_RS06895	COG3001	Fructosamine kinase
FOB88_RS06905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB88_RS06910	COG1988	membrane-bound metal-dependent
FOB88_RS06925	COG3385	transposase activity
FOB88_RS06930	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB88_RS06935	COG2814	Major facilitator Superfamily
FOB88_RS06945	COG0840	transmembrane signaling receptor activity
FOB88_RS06955	COG0322	excinuclease ABC activity
FOB88_RS06960	COG3678	ATP-independent chaperone mediated protein folding
FOB88_RS06965	COG2988	succinylglutamate desuccinylase activity
FOB88_RS06970	COG3724	N-succinylarginine dihydrolase activity
FOB88_RS06975	COG1012	belongs to the aldehyde dehydrogenase family
FOB88_RS06995	COG4932	domain protein
FOB88_RS07000	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS07005	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS07010	COG1129	ABC transporter
FOB88_RS07020	COG1879	ABC-type sugar transport system periplasmic component
FOB88_RS07025	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS07030	COG1349	DNA-binding transcription factor activity
FOB88_RS07035	COG1648	precorrin-2 dehydrogenase activity
FOB88_RS07035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOB88_RS07040	COG0243	molybdopterin cofactor binding
FOB88_RS07045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB88_RS07045	COG2146	nitrite reductase [NAD(P)H] activity
FOB88_RS07050	COG1116	anion transmembrane transporter activity
FOB88_RS07060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB88_RS07065	COG3707	response regulator
FOB88_RS07075	COG1360	Flagellar Motor Protein
FOB88_RS07105	COG0515	serine threonine protein kinase
FOB88_RS07110	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FOB88_RS07115	COG4572	Cation transport regulator
FOB88_RS07120	COG0387	Pfam Sodium calcium exchanger
FOB88_RS07130	COG2912	Transglutaminase-like superfamily
FOB88_RS07145	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOB88_RS07150	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOB88_RS07155	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FOB88_RS07160	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOB88_RS07165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOB88_RS07180	COG0193	aminoacyl-tRNA hydrolase activity
FOB88_RS07185	COG0012	GTP binding
FOB88_RS07190	COG0582	viral genome integration into host DNA
FOB88_RS07245	COG3209	COG3209 Rhs family protein
FOB88_RS07325	COG0840	transmembrane signaling receptor activity
FOB88_RS07335	COG0673	inositol 2-dehydrogenase activity
FOB88_RS07345	COG2814	Major facilitator Superfamily
FOB88_RS07345	COG0477	Major facilitator Superfamily
FOB88_RS07365	COG0386	Belongs to the glutathione peroxidase family
FOB88_RS07375	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB88_RS07385	COG1403	HNH endonuclease
FOB88_RS07395	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB88_RS07395	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB88_RS07405	COG0531	amino acid
FOB88_RS07415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB88_RS07420	COG3038	cytochrome b561
FOB88_RS07450	COG0840	transmembrane signaling receptor activity
FOB88_RS07480	COG1846	Transcriptional regulator
FOB88_RS07480	COG1940	carbohydrate kinase activity
FOB88_RS07495	COG3842	ATPase activity
FOB88_RS07500	COG0483	inositol monophosphate 1-phosphatase activity
FOB88_RS07505	COG1304	FMN binding
FOB88_RS07515	COG0640	Transcriptional regulator
FOB88_RS07520	COG1902	pentaerythritol trinitrate reductase activity
FOB88_RS07525	COG3002	Belongs to the UPF0753 family
FOB88_RS07530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOB88_RS07535	COG0583	DNA-binding transcription factor activity
FOB88_RS07550	COG2140	Oxalate decarboxylase
FOB88_RS07560	COG1012	belongs to the aldehyde dehydrogenase family
FOB88_RS07570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOB88_RS07570	COG0519	Catalyzes the synthesis of GMP from XMP
FOB88_RS07575	COG0697	spore germination
FOB88_RS07585	COG3381	protein complex oligomerization
FOB88_RS07590	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOB88_RS07605	COG2261	transglycosylase associated protein
FOB88_RS07610	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FOB88_RS07615	COG0668	transmembrane transport
FOB88_RS07620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOB88_RS07625	COG3958	Transketolase
FOB88_RS07630	COG3959	Transketolase, thiamine diphosphate binding domain
FOB88_RS07635	COG2390	Transcriptional regulator
FOB88_RS07645	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOB88_RS07685	COG0477	Major facilitator Superfamily
FOB88_RS07690	COG2188	Transcriptional regulator
FOB88_RS07695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB88_RS07700	COG1397	ADP-ribosylglycohydrolase
FOB88_RS07705	COG2211	Major facilitator Superfamily
FOB88_RS07720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB88_RS07735	COG1309	transcriptional regulator
FOB88_RS07740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB88_RS07775	COG3121	Chaperone
FOB88_RS07785	COG0538	isocitrate dehydrogenase activity
FOB88_RS07790	COG1187	pseudouridine synthase activity
FOB88_RS07805	COG2915	High frequency lysogenization protein hflD homolog
FOB88_RS07810	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOB88_RS07820	COG2205	protein histidine kinase activity
FOB88_RS07825	COG2850	peptidyl-arginine hydroxylation
FOB88_RS07830	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB88_RS07835	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOB88_RS07840	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB88_RS07850	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB88_RS07860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOB88_RS07865	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB88_RS07875	COG3134	Outer membrane lipoprotein
FOB88_RS07880	COG1252	NADH dehydrogenase
FOB88_RS07890	COG1472	Belongs to the glycosyl hydrolase 3 family
FOB88_RS07900	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FOB88_RS07905	COG5633	Lipoprotein
FOB88_RS07910	COG0537	adenosine 5'-monophosphoramidase activity
FOB88_RS07915	COG0840	transmembrane signaling receptor activity
FOB88_RS07920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB88_RS07920	COG1263	PTS System
FOB88_RS07925	COG0084	hydrolase, TatD family'
FOB88_RS07930	COG0470	DNA polymerase III
FOB88_RS07935	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOB88_RS07940	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOB88_RS07945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB88_RS07950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB88_RS07960	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS07965	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOB88_RS07970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOB88_RS07980	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOB88_RS07995	COG0564	pseudouridine synthase activity
FOB88_RS08000	COG1530	ribonuclease E activity
FOB88_RS08035	COG4787	bacterial-type flagellum-dependent cell motility
FOB88_RS08050	COG1558	bacterial-type flagellum-dependent cell motility
FOB88_RS08075	COG0840	transmembrane signaling receptor activity
FOB88_RS08095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB88_RS08105	COG0418	dihydroorotase activity
FOB88_RS08130	COG3038	cytochrome b561
FOB88_RS08145	COG1560	Kdo2-lipid A biosynthetic process
FOB88_RS08170	COG5645	(Lipo)protein
FOB88_RS08175	COG2943	transferase activity, transferring hexosyl groups
FOB88_RS08190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB88_RS08245	COG0659	secondary active sulfate transmembrane transporter activity
FOB88_RS08315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOB88_RS08325	COG2197	response regulator
FOB88_RS08340	COG2197	response regulator
FOB88_RS08355	COG1113	amino acid transport
FOB88_RS08365	COG1309	transcriptional regulator
FOB88_RS08390	COG1012	belongs to the aldehyde dehydrogenase family
FOB88_RS08410	COG0670	Belongs to the BI1 family
FOB88_RS08415	COG2920	part of a sulfur-relay system
FOB88_RS08425	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOB88_RS08435	COG1832	CoA-binding protein
FOB88_RS08450	COG0210	DNA helicase
FOB88_RS08455	COG3304	Inner membrane component domain
FOB88_RS08460	COG1289	transmembrane transporter activity
FOB88_RS08465	COG3070	regulator of competence-specific genes
FOB88_RS08480	COG3120	sequence-specific DNA binding
FOB88_RS08485	COG1067	ATP-dependent peptidase activity
FOB88_RS08490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB88_RS08495	COG3130	regulation of translation
FOB88_RS08500	COG3009	Protein conserved in bacteria
FOB88_RS08505	COG3008	intermembrane lipid transfer
FOB88_RS08505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOB88_RS08510	COG2995	paraquat-inducible protein a
FOB88_RS08515	COG0488	(ABC) transporter
FOB88_RS08520	COG0116	Belongs to the methyltransferase superfamily
FOB88_RS08520	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOB88_RS08525	COG0633	Ferredoxin
FOB88_RS08525	COG3217	Mosc domain protein beta barrel domain protein
FOB88_RS08535	COG0167	dihydroorotate dehydrogenase activity
FOB88_RS08545	COG1216	Glycosyl transferase, family 2
FOB88_RS08550	COG0431	NADPH-dependent FMN reductase
FOB88_RS08555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB88_RS08560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB88_RS08565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB88_RS08575	COG0308	aminopeptidase N
FOB88_RS08580	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOB88_RS08585	COG0017	Asparaginyl-tRNA synthetase
FOB88_RS08600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB88_RS08605	COG3108	Peptidase M15
FOB88_RS08610	COG2989	Protein conserved in bacteria
FOB88_RS08620	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FOB88_RS08625	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FOB88_RS08630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB88_RS08635	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOB88_RS08640	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FOB88_RS08645	COG2835	tetraacyldisaccharide 4'-kinase activity
FOB88_RS08650	COG3214	Protein conserved in bacteria
FOB88_RS08665	COG2333	competence protein COMEC
FOB88_RS08665	COG0658	competence protein
FOB88_RS08670	COG0776	regulation of translation
FOB88_RS08675	COG0539	negative regulation of cytoplasmic translation
FOB88_RS08680	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOB88_RS08690	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOB88_RS08695	COG1944	ATP diphosphatase activity
FOB88_RS08700	COG2116	formate transmembrane transporter activity
FOB88_RS08705	COG1882	Formate acetyltransferase
FOB88_RS08710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB88_RS08715	COG0477	Major facilitator Superfamily
FOB88_RS08720	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOB88_RS08725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOB88_RS08730	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOB88_RS08735	COG1674	ftsk spoiiie
FOB88_RS08735	COG3107	peptidoglycan biosynthetic process
FOB88_RS08745	COG0492	ferredoxin-NADP+ reductase activity
FOB88_RS08750	COG4988	ABC transporter
FOB88_RS08755	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOB88_RS08760	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FOB88_RS08765	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOB88_RS08770	COG0542	response to heat
FOB88_RS08775	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOB88_RS08780	COG1278	Cold shock
FOB88_RS08785	COG3593	DNA synthesis involved in DNA repair
FOB88_RS08790	COG2431	L-lysine efflux transmembrane transporter activity
FOB88_RS08795	COG0028	Belongs to the TPP enzyme family
FOB88_RS08800	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FOB88_RS08805	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOB88_RS08810	COG0393	Putative heavy-metal-binding
FOB88_RS08820	COG1126	abc transporter atp-binding protein
FOB88_RS08825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB88_RS08830	COG4215	(ABC) transporter
FOB88_RS08835	COG4160	amino acid transport
FOB88_RS08840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB88_RS08855	COG1177	transmembrane transport
FOB88_RS08860	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOB88_RS08865	COG3842	ATPase activity
FOB88_RS08870	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOB88_RS08880	COG0189	ligase activity
FOB88_RS08885	COG0778	Nitroreductase
FOB88_RS08910	COG0671	phosphoesterase, PA-phosphatase related
FOB88_RS08915	COG1686	Belongs to the peptidase S11 family
FOB88_RS08925	COG2133	pyrroloquinoline quinone binding
FOB88_RS08960	COG4172	Belongs to the ABC transporter superfamily
FOB88_RS08970	COG0303	'Molybdopterin
FOB88_RS08975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB88_RS08980	COG0488	(ABC) transporter
FOB88_RS08985	COG2916	Histone family protein nucleoid-structuring protein H-NS
FOB88_RS08995	COG2814	Major facilitator Superfamily
FOB88_RS09000	COG1566	PFAM secretion protein HlyD family protein
FOB88_RS09005	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOB88_RS09010	COG1321	iron dependent repressor
FOB88_RS09020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOB88_RS09025	COG5006	permease, DMT superfamily
FOB88_RS09030	COG0783	Belongs to the Dps family
FOB88_RS09035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB88_RS09040	COG0765	amino acid transport
FOB88_RS09045	COG1126	abc transporter atp-binding protein
FOB88_RS09050	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FOB88_RS09065	COG2986	histidine ammonia-lyase
FOB88_RS09095	COG1228	amidohydrolase
FOB88_RS09100	COG0402	S-adenosylhomocysteine deaminase activity
FOB88_RS09115	COG2986	histidine ammonia-lyase
FOB88_RS09125	COG2271	Major facilitator Superfamily
FOB88_RS09135	COG1609	Transcriptional regulator
FOB88_RS09140	COG1473	amidohydrolase
FOB88_RS09145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOB88_RS09165	COG0789	Transcriptional regulator
FOB88_RS09170	COG1174	glycine betaine transport
FOB88_RS09175	COG1125	glycine betaine transport
FOB88_RS09180	COG1174	glycine betaine transport
FOB88_RS09185	COG1732	Glycine betaine
FOB88_RS09190	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FOB88_RS09195	COG0840	transmembrane signaling receptor activity
FOB88_RS09205	COG1472	Belongs to the glycosyl hydrolase 3 family
FOB88_RS09210	COG0277	FAD linked oxidase domain protein
FOB88_RS09215	COG1511	domain protein
FOB88_RS09215	COG3264	Mechanosensitive ion channel
FOB88_RS09220	COG1686	Belongs to the peptidase S11 family
FOB88_RS09230	COG0586	Pfam SNARE associated Golgi protein
FOB88_RS09235	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS09240	COG3387	PFAM Glycoside hydrolase 15-related
FOB88_RS09245	COG1376	ErfK ybiS ycfS ynhG family protein
FOB88_RS09255	COG0306	phosphate transporter
FOB88_RS09265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB88_RS09270	COG0513	Belongs to the DEAD box helicase family
FOB88_RS09280	COG3568	Endonuclease Exonuclease Phosphatase
FOB88_RS09285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB88_RS09290	COG0392	lysyltransferase activity
FOB88_RS09295	COG0670	Belongs to the BI1 family
FOB88_RS09305	COG0314	molybdopterin synthase activity
FOB88_RS09310	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FOB88_RS09315	COG0315	cyclic pyranopterin monophosphate synthase activity
FOB88_RS09320	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOB88_RS09335	COG0556	nucleotide-excision repair
FOB88_RS09345	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOB88_RS09350	COG2226	methyltransferase
FOB88_RS09360	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOB88_RS09370	COG1881	PFAM PEBP family protein
FOB88_RS09375	COG2706	6-phosphogluconolactonase activity
FOB88_RS09380	COG0561	phosphatase activity
FOB88_RS09390	COG4149	molybdate abc transporter
FOB88_RS09395	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOB88_RS09405	COG2005	Transcriptional regulator
FOB88_RS09405	COG3585	molybdate ion transport
FOB88_RS09410	COG1119	ATPase activity
FOB88_RS09415	COG1085	galactose-1-phosphate uridylyltransferase
FOB88_RS09425	COG2017	converts alpha-aldose to the beta-anomer
FOB88_RS09430	COG0588	phosphoglycerate mutase activity
FOB88_RS09435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB88_RS09445	COG2197	response regulator
FOB88_RS09450	COG2205	protein histidine kinase activity
FOB88_RS09450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB88_RS09455	COG1230	cation diffusion facilitator family transporter
FOB88_RS09470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOB88_RS09480	COG0840	transmembrane signaling receptor activity
FOB88_RS09505	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FOB88_RS09510	COG2885	chlorophyll binding
FOB88_RS09520	COG3064	Membrane
FOB88_RS09525	COG0848	biopolymer transport protein
FOB88_RS09530	COG0811	peptide transport
FOB88_RS09535	COG0824	Thioesterase
FOB88_RS09540	COG3790	cyd operon protein YbgE
FOB88_RS09545	COG4890	Cyd operon protein YbgT
FOB88_RS09550	COG1294	oxidase, subunit
FOB88_RS09555	COG1271	oxidase subunit
FOB88_RS09560	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOB88_RS09565	COG0045	succinate-CoA ligase (ADP-forming) activity
FOB88_RS09570	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB88_RS09575	COG0567	Dehydrogenase, E1 component
FOB88_RS09580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOB88_RS09590	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOB88_RS09600	COG0372	Belongs to the citrate synthase family
FOB88_RS09605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB88_RS09615	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FOB88_RS09630	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FOB88_RS09635	COG1984	allophanate hydrolase subunit 2
FOB88_RS09640	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOB88_RS09655	COG3272	Protein of unknown function (DUF1722)
FOB88_RS09665	COG0745	RESPONSE REGULATOR receiver
FOB88_RS09670	COG0033	Phosphoglucomutase
FOB88_RS09675	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FOB88_RS09680	COG0596	Alpha beta hydrolase
FOB88_RS09695	COG0735	belongs to the Fur family
FOB88_RS09705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB88_RS09710	COG3385	transposase activity
FOB88_RS09715	COG2190	(PTS) system
FOB88_RS09715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB88_RS09715	COG1263	PTS System
FOB88_RS09720	COG0363	glucosamine-6-phosphate deaminase activity
FOB88_RS09725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOB88_RS09730	COG1846	Transcriptional regulator
FOB88_RS09730	COG1940	carbohydrate kinase activity
FOB88_RS09735	COG0647	UMP catabolic process
FOB88_RS09740	COG0367	asparagine synthase
FOB88_RS09780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB88_RS09790	COG1702	phosphate starvation-inducible protein PhoH
FOB88_RS09795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOB88_RS09800	COG4535	Mg2 and Co2 transporter CorC
FOB88_RS09805	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FOB88_RS09820	COG0765	amino acid transport
FOB88_RS09825	COG0765	amino acid transport
FOB88_RS09830	COG1126	abc transporter atp-binding protein
FOB88_RS09835	COG2888	peptidyl-tyrosine sulfation
FOB88_RS09840	COG0495	leucyl-tRNA aminoacylation
FOB88_RS09845	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FOB88_RS09850	COG1466	dna polymerase III delta subunit
FOB88_RS09860	COG0799	negative regulation of ribosome biogenesis
FOB88_RS09865	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOB88_RS09870	COG0768	penicillin binding
FOB88_RS09875	COG0772	Belongs to the SEDS family
FOB88_RS09880	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOB88_RS09885	COG1686	Belongs to the peptidase S11 family
FOB88_RS09895	COG0321	lipoyl(octanoyl) transferase activity
FOB88_RS09900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOB88_RS09905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB88_RS09910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB88_RS09920	COG1278	Cold shock
FOB88_RS09935	COG2610	gluconate transmembrane transporter activity
FOB88_RS09940	COG1454	alcohol dehydrogenase
FOB88_RS09945	COG0561	phosphatase activity
FOB88_RS09955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB88_RS09960	COG0814	amino acid
FOB88_RS09965	COG1063	alcohol dehydrogenase
FOB88_RS09970	COG0671	phosphoesterase, PA-phosphatase related
FOB88_RS09975	COG0628	permease
FOB88_RS09995	COG1597	lipid kinase activity
FOB88_RS09995	COG1803	Methylglyoxal synthase
FOB88_RS10015	COG2264	protein methyltransferase activity
FOB88_RS10030	COG2814	Major facilitator Superfamily
FOB88_RS10050	COG4529	Protein conserved in bacteria
FOB88_RS10065	COG2211	Major facilitator Superfamily
FOB88_RS10135	COG3609	addiction module antidote protein, CC2985 family
FOB88_RS10185	COG2831	hemolysin activation secretion protein
FOB88_RS10205	COG1484	DNA-dependent DNA replication
FOB88_RS10365	COG4974	Belongs to the 'phage' integrase family
FOB88_RS10375	COG3311	Transcriptional regulator
FOB88_RS10385	COG0582	viral genome integration into host DNA
FOB88_RS10400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOB88_RS10405	COG2501	S4 domain
FOB88_RS10410	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOB88_RS10415	COG0215	cysteine-tRNA ligase activity
FOB88_RS10420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB88_RS10435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOB88_RS10440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOB88_RS10445	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FOB88_RS10450	COG4181	ATPase activity
FOB88_RS10455	COG2755	lipolytic protein G-D-S-L family
FOB88_RS10460	COG0300	oxidoreductase activity
FOB88_RS10465	COG3118	belongs to the thioredoxin family
FOB88_RS10470	COG0330	HflC and HflK could
FOB88_RS10475	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOB88_RS10495	COG3735	TraB family
FOB88_RS10500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB88_RS10515	COG0737	Belongs to the 5'-nucleotidase family
FOB88_RS10520	COG4651	solute:proton antiporter activity
FOB88_RS10520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB88_RS10525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB88_RS10530	COG0563	adenylate kinase activity
FOB88_RS10535	COG0326	Molecular chaperone. Has ATPase activity
FOB88_RS10540	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOB88_RS10545	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOB88_RS10555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB88_RS10560	COG2832	Protein of unknown function (DUF454)
FOB88_RS10575	COG1309	transcriptional regulator
FOB88_RS10580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB88_RS10585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB88_RS10590	COG0254	rRNA binding
FOB88_RS10595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOB88_RS10600	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOB88_RS10605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB88_RS10610	COG1121	(ABC) transporter
FOB88_RS10635	COG3695	enzyme binding
FOB88_RS10640	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FOB88_RS10645	COG1946	Acyl-CoA thioesterase
FOB88_RS10650	COG0004	ammonium transporteR
FOB88_RS10655	COG0347	Belongs to the P(II) protein family
FOB88_RS10660	COG1132	(ABC) transporter
FOB88_RS10665	COG1132	(ABC) transporter
FOB88_RS10670	COG1522	sequence-specific DNA binding
FOB88_RS10685	COG0824	Thioesterase
FOB88_RS10690	COG1555	photosystem II stabilization
FOB88_RS10695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB88_RS10700	COG0776	regulation of translation
FOB88_RS10720	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOB88_RS10725	COG0271	Belongs to the BolA IbaG family
FOB88_RS10730	COG3056	Lipoprotein
FOB88_RS10735	COG2223	nitrite transmembrane transporter activity
FOB88_RS10740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOB88_RS10745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOB88_RS10750	COG1845	cytochrome c oxidase, subunit III
FOB88_RS10755	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOB88_RS10760	COG0109	protoheme IX farnesyltransferase activity
FOB88_RS10765	COG2814	Major facilitator Superfamily
FOB88_RS10775	COG1012	belongs to the aldehyde dehydrogenase family
FOB88_RS10780	COG3284	Transcriptional regulator
FOB88_RS10785	COG1666	GTP binding
FOB88_RS10790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOB88_RS10795	COG0693	protein deglycase activity
FOB88_RS10800	COG0301	tRNA thio-modification
FOB88_RS10800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB88_RS10805	COG1722	exodeoxyribonuclease VII activity
FOB88_RS10810	COG0142	geranyltranstransferase activity
FOB88_RS10815	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOB88_RS10820	COG0667	Aldo Keto reductase
FOB88_RS10825	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOB88_RS10830	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOB88_RS10835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB88_RS10840	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOB88_RS10845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB88_RS10845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB88_RS10850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOB88_RS10855	COG4238	major outer membrane lipoprotein
FOB88_RS10860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB88_RS10865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB88_RS10870	COG1862	Preprotein translocase
FOB88_RS10875	COG0343	queuine tRNA-ribosyltransferase activity
FOB88_RS10880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOB88_RS11005	COG5484	DNA packaging
FOB88_RS11005	COG3728	DNA packaging
FOB88_RS11015	COG1484	DNA-dependent DNA replication
FOB88_RS11120	COG0305	Participates in initiation and elongation during chromosome replication
FOB88_RS11290	COG0582	viral genome integration into host DNA
FOB88_RS11300	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FOB88_RS11315	COG1113	amino acid transport
FOB88_RS11320	COG1114	Component of the transport system for branched-chain amino acids
FOB88_RS11325	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB88_RS11335	COG5002	protein histidine kinase activity
FOB88_RS11340	COG0745	RESPONSE REGULATOR receiver
FOB88_RS11345	COG0420	3'-5' exonuclease activity
FOB88_RS11350	COG0419	ATPase involved in DNA repair
FOB88_RS11360	COG1940	carbohydrate kinase activity
FOB88_RS11365	COG2974	May be involved in recombination
FOB88_RS11370	COG3123	guanosine phosphorylase activity
FOB88_RS11380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOB88_RS11385	COG3416	Protein conserved in bacteria
FOB88_RS11390	COG1671	Belongs to the UPF0178 family
FOB88_RS11395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOB88_RS11440	COG1609	Transcriptional regulator
FOB88_RS11445	COG2723	6-phospho-beta-galactosidase activity
FOB88_RS11450	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOB88_RS11455	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB88_RS11475	COG1764	response to oxidative stress
FOB88_RS11485	COG2186	Transcriptional regulator
FOB88_RS11495	COG2807	transmembrane transport
FOB88_RS11500	COG0583	DNA-binding transcription factor activity
FOB88_RS11505	COG0402	S-adenosylhomocysteine deaminase activity
FOB88_RS11515	COG0513	Belongs to the DEAD box helicase family
FOB88_RS11525	COG0784	Response regulator, receiver
FOB88_RS11525	COG0835	chemotaxis
FOB88_RS11530	COG1278	Cold shock
FOB88_RS11535	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB88_RS11565	COG1476	TRANSCRIPTIONal
FOB88_RS11630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB88_RS11630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB88_RS11630	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FOB88_RS11635	COG1461	Dihydroxyacetone kinase
FOB88_RS11640	COG2376	Dihydroxyacetone kinase
FOB88_RS11685	COG2932	Transcriptional regulator
FOB88_RS11690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOB88_RS11695	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOB88_RS11700	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB88_RS11715	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FOB88_RS11720	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB88_RS11730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOB88_RS11735	COG1129	ABC transporter
FOB88_RS11740	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS11755	COG3034	peptidoglycan biosynthetic process
FOB88_RS11760	COG0121	glutamine amidotransferase
FOB88_RS11785	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FOB88_RS11790	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FOB88_RS11800	COG0436	Aminotransferase
FOB88_RS11810	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FOB88_RS11830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOB88_RS11840	COG0765	amino acid transport
FOB88_RS11880	COG0583	DNA-binding transcription factor activity
FOB88_RS11905	COG2072	flavoprotein involved in K transport
FOB88_RS11910	COG0583	DNA-binding transcription factor activity
FOB88_RS11950	COG1953	Uracil, thiamine, allantoin
FOB88_RS11970	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS11975	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB88_RS11980	COG1349	DNA-binding transcription factor activity
FOB88_RS11985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOB88_RS11985	COG0517	IMP dehydrogenase activity
FOB88_RS11990	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB88_RS12010	COG2226	methyltransferase
FOB88_RS12015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB88_RS12020	COG0741	lytic transglycosylase activity
FOB88_RS12020	COG1388	LysM domain
FOB88_RS12025	COG3021	interspecies interaction between organisms
FOB88_RS12030	COG0583	DNA-binding transcription factor activity
FOB88_RS12060	COG0542	response to heat
FOB88_RS12070	COG0564	pseudouridine synthase activity
FOB88_RS12075	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB88_RS12080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOB88_RS12085	COG1605	Chorismate mutase
FOB88_RS12085	COG0077	Prephenate dehydratase
FOB88_RS12090	COG1605	Chorismate mutase
FOB88_RS12090	COG0287	Prephenate dehydrogenase
FOB88_RS12095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB88_RS12125	COG0228	four-way junction DNA binding
FOB88_RS12130	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOB88_RS12135	COG4137	Cytochrome C assembly protein
FOB88_RS12140	COG4536	flavin adenine dinucleotide binding
FOB88_RS12145	COG1854	S-ribosylhomocysteine lyase activity
FOB88_RS12150	COG2918	glutathione biosynthetic process
FOB88_RS12155	COG1238	metal cluster binding
FOB88_RS12160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB88_RS12190	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FOB88_RS12205	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOB88_RS12220	COG2824	Alkylphosphonate utilization operon protein PhnA
FOB88_RS12225	COG2951	lytic endotransglycosylase activity
FOB88_RS12230	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOB88_RS12245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOB88_RS12250	COG1388	LysM domain
FOB88_RS12250	COG4942	peptidase
FOB88_RS12255	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOB88_RS12260	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOB88_RS12265	COG0585	pseudouridine synthase activity
FOB88_RS12280	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FOB88_RS12295	COG2895	sulfate adenylyltransferase (ATP) activity
FOB88_RS12305	COG1648	precorrin-2 dehydrogenase activity
FOB88_RS12305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOB88_RS12310	COG2234	aminopeptidase activity
FOB88_RS12330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB88_RS12335	COG0765	amino acid transport
FOB88_RS12340	COG0765	amino acid transport
FOB88_RS12360	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB88_RS12365	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOB88_RS12375	COG0720	synthase
FOB88_RS12380	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOB88_RS12385	COG0602	queuosine metabolic process
FOB88_RS12405	COG0148	phosphopyruvate hydratase activity
FOB88_RS12410	COG0504	CTP synthase activity
FOB88_RS12415	COG3956	TIGRFAM MazG family protein
FOB88_RS12420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB88_RS12425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB88_RS12435	COG1929	Belongs to the glycerate kinase type-1 family
FOB88_RS12440	COG2084	Dehydrogenase
FOB88_RS12445	COG3836	Belongs to the HpcH HpaI aldolase family
FOB88_RS12450	COG4948	Mandelate Racemase Muconate Lactonizing
FOB88_RS12455	COG4948	Mandelate Racemase Muconate Lactonizing
FOB88_RS12460	COG2271	Major facilitator Superfamily
FOB88_RS12465	COG2721	sulfolactate sulfo-lyase activity
FOB88_RS12470	COG0716	FMN binding
FOB88_RS12475	COG0564	pseudouridine synthase activity
FOB88_RS12480	COG3098	single-species biofilm formation
FOB88_RS12490	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOB88_RS12490	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOB88_RS12495	COG1611	Belongs to the LOG family
FOB88_RS12505	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FOB88_RS12510	COG2363	Small membrane protein
FOB88_RS12515	COG0583	DNA-binding transcription factor activity
FOB88_RS12525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOB88_RS12530	COG2166	iron-sulfur cluster assembly
FOB88_RS12535	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOB88_RS12540	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FOB88_RS12565	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOB88_RS12570	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOB88_RS12570	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB88_RS12575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB88_RS12580	COG1074	ATP-dependent DNA helicase activity
FOB88_RS12585	COG1025	Belongs to the peptidase M16 family
FOB88_RS12590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FOB88_RS12605	COG4795	General secretion pathway protein
FOB88_RS12610	COG2165	general secretion pathway protein
FOB88_RS12615	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOB88_RS12620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOB88_RS12630	COG1051	belongs to the nudix hydrolase family
FOB88_RS12635	COG3066	DNA modification
FOB88_RS12640	COG0861	Integral membrane protein TerC family
FOB88_RS12650	COG0667	Aldo Keto reductase
FOB88_RS12660	COG0583	DNA-binding transcription factor activity
FOB88_RS12665	COG2814	Major facilitator Superfamily
FOB88_RS12680	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOB88_RS12690	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOB88_RS12695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB88_RS12700	COG4974	Belongs to the 'phage' integrase family
FOB88_RS12705	COG0716	FMN binding
FOB88_RS12715	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FOB88_RS12725	COG1272	protein, Hemolysin III
FOB88_RS12730	COG1737	Transcriptional regulator
FOB88_RS12735	COG2723	6-phospho-beta-galactosidase activity
FOB88_RS12740	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS12745	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOB88_RS12745	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOB88_RS12755	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOB88_RS12760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB88_RS12765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB88_RS12770	COG0006	proline dipeptidase activity
FOB88_RS12780	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FOB88_RS12790	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOB88_RS12795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB88_RS12805	COG0583	DNA-binding transcription factor activity
FOB88_RS12820	COG0668	transmembrane transport
FOB88_RS12830	COG0191	fructose-bisphosphate aldolase activity
FOB88_RS12835	COG0126	phosphoglycerate kinase activity
FOB88_RS12845	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOB88_RS12850	COG0501	Belongs to the peptidase M48B family
FOB88_RS12860	COG1166	arginine decarboxylase activity
FOB88_RS12870	COG2814	Major facilitator Superfamily
FOB88_RS12875	COG0840	transmembrane signaling receptor activity
FOB88_RS12885	COG2356	endonuclease I
FOB88_RS12890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB88_RS12900	COG1678	Uncharacterized ACR, COG1678
FOB88_RS12910	COG2805	Type II/IV secretion system protein
FOB88_RS12915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOB88_RS12920	COG0762	integral membrane protein
FOB88_RS12925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOB88_RS12930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB88_RS12935	COG2188	Transcriptional regulator
FOB88_RS12940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB88_RS12960	COG3171	Protein conserved in bacteria
FOB88_RS12970	COG2169	Transcriptional regulator
FOB88_RS12975	COG1486	melibiose metabolic process
FOB88_RS12980	COG2211	Major facilitator Superfamily
FOB88_RS12985	COG1194	a g-specific adenine glycosylase
FOB88_RS12995	COG0741	lytic transglycosylase activity
FOB88_RS13000	COG1982	Orn Lys Arg decarboxylase major
FOB88_RS13005	COG0604	alcohol dehydrogenase
FOB88_RS13015	COG1695	Transcriptional regulator
FOB88_RS13020	COG2375	cellular response to nickel ion
FOB88_RS13030	COG2207	Transcriptional regulator
FOB88_RS13030	COG3708	Transcriptional regulator
FOB88_RS13040	COG1294	oxidase, subunit
FOB88_RS13045	COG1271	oxidase subunit
FOB88_RS13050	COG1733	regulation of RNA biosynthetic process
FOB88_RS13055	COG0702	epimerase
FOB88_RS13070	COG0640	Transcriptional regulator
FOB88_RS13085	COG3685	Protein conserved in bacteria
FOB88_RS13090	COG3685	Protein conserved in bacteria
FOB88_RS13095	COG3729	General stress protein
FOB88_RS13105	COG2203	Gaf domain
FOB88_RS13105	COG2199	diguanylate cyclase activity
FOB88_RS13120	COG0840	transmembrane signaling receptor activity
FOB88_RS13160	COG2814	Major facilitator Superfamily
FOB88_RS13175	COG2814	Major facilitator Superfamily
FOB88_RS13200	COG2199	diguanylate cyclase activity
FOB88_RS13200	COG2203	Gaf domain
FOB88_RS13220	COG3188	usher protein
FOB88_RS13245	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOB88_RS13255	COG0305	Participates in initiation and elongation during chromosome replication
FOB88_RS13305	COG0442	prolyl-tRNA aminoacylation
FOB88_RS13310	COG0495	leucyl-tRNA aminoacylation
FOB88_RS13325	COG0813	purine-nucleoside phosphorylase activity
FOB88_RS13330	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOB88_RS13335	COG2226	methyltransferase
FOB88_RS13350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB88_RS13360	COG0629	single-stranded DNA binding
FOB88_RS13425	COG0741	lytic transglycosylase activity
FOB88_RS13585	COG4581	dead DEAH box helicase
FOB88_RS13670	COG1484	DNA-dependent DNA replication
FOB88_RS13735	COG2801	Transposase and inactivated derivatives
FOB88_RS13760	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOB88_RS13785	COG3706	GGDEF domain
FOB88_RS13795	COG0813	purine-nucleoside phosphorylase activity
FOB88_RS13800	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOB88_RS13805	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOB88_RS13815	COG0084	hydrolase, TatD family'
FOB88_RS13820	COG4667	esterase of the alpha-beta hydrolase superfamily
FOB88_RS13830	COG2823	Periplasmic or secreted lipoprotein
FOB88_RS13835	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOB88_RS13845	COG1528	Iron-storage protein
FOB88_RS13855	COG2271	Major facilitator Superfamily
FOB88_RS13860	COG1609	Transcriptional regulator
FOB88_RS13865	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOB88_RS13880	COG3842	ATPase activity
FOB88_RS13890	COG4297	protein containing double-stranded beta helix domain
FOB88_RS13900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB88_RS13940	COG0848	biopolymer transport protein
FOB88_RS13950	COG1263	PTS System
FOB88_RS13950	COG2190	(PTS) system
FOB88_RS13950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB88_RS13955	COG1609	Transcriptional regulator
FOB88_RS13975	COG3485	protocatechuate 3,4-dioxygenase
FOB88_RS13980	COG3485	protocatechuate 3,4-dioxygenase
FOB88_RS13985	COG0583	DNA-binding transcription factor activity
FOB88_RS13990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOB88_RS14000	COG0183	Belongs to the thiolase family
FOB88_RS14005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOB88_RS14010	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOB88_RS14015	COG1414	Transcriptional regulator
FOB88_RS14020	COG0626	cystathionine gamma-synthase activity
FOB88_RS14025	COG0586	Pfam SNARE associated Golgi protein
FOB88_RS14030	COG2207	Transcriptional regulator
FOB88_RS14035	COG0656	L-ascorbic acid biosynthetic process
FOB88_RS14045	COG2132	Multicopper oxidase
FOB88_RS14055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOB88_RS14060	COG3711	transcriptional antiterminator
FOB88_RS14065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB88_RS14065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB88_RS14065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB88_RS14075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB88_RS14075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB88_RS14085	COG0191	fructose-bisphosphate aldolase activity
FOB88_RS14095	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB88_RS14100	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOB88_RS14105	COG0187	DNA topoisomerase II activity
FOB88_RS14110	COG3150	esterase
FOB88_RS14115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOB88_RS14120	COG3151	Protein conserved in bacteria
FOB88_RS14125	COG0494	nUDIX hydrolase
FOB88_RS14130	COG1538	Outer membrane efflux protein
FOB88_RS14135	COG5463	Belongs to the UPF0441 family
FOB88_RS14140	COG0754	glutathionylspermidine amidase activity
FOB88_RS14145	COG3384	dioxygenase
FOB88_RS14150	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB88_RS14155	COG2960	long-chain fatty acid transporting porin activity
FOB88_RS14170	COG3025	triphosphatase activity
FOB88_RS14175	COG4991	sh3 domain protein
FOB88_RS14180	COG0617	tRNA 3'-terminal CCA addition
FOB88_RS14185	COG1968	undecaprenyl-diphosphatase activity
FOB88_RS14190	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOB88_RS14205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOB88_RS14210	COG0358	DNA primase activity
FOB88_RS14295	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOB88_RS14395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOB88_RS14425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB88_RS14425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB88_RS14425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB88_RS14430	COG3711	transcriptional antiterminator
FOB88_RS14435	COG0659	secondary active sulfate transmembrane transporter activity
FOB88_RS14440	COG0840	transmembrane signaling receptor activity
FOB88_RS14445	COG0840	transmembrane signaling receptor activity
FOB88_RS14485	COG3300	MHYT domain
FOB88_RS14485	COG5001	Diguanylate cyclase
FOB88_RS14495	COG0840	transmembrane signaling receptor activity
FOB88_RS14505	COG3706	GGDEF domain
FOB88_RS14515	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOB88_RS14520	COG2199	diguanylate cyclase activity
FOB88_RS14525	COG0659	secondary active sulfate transmembrane transporter activity
FOB88_RS14530	COG0288	reversible hydration of carbon dioxide
FOB88_RS14535	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOB88_RS14545	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB88_RS14545	COG1902	pentaerythritol trinitrate reductase activity
FOB88_RS14550	COG2813	Specifically methylates the guanine in position
FOB88_RS14555	COG1451	nucleotide metabolic process
FOB88_RS14560	COG0038	chloride channel
FOB88_RS14565	COG0673	inositol 2-dehydrogenase activity
FOB88_RS14575	COG2721	sulfolactate sulfo-lyase activity
FOB88_RS14590	COG2271	Major facilitator Superfamily
FOB88_RS14600	COG0586	Pfam SNARE associated Golgi protein
FOB88_RS14610	COG1422	Protein of unknown function (DUF1090)
FOB88_RS14615	COG4575	ribosome binding
FOB88_RS14620	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FOB88_RS14630	COG2259	Doxx family
FOB88_RS14650	COG0435	Glutathione S-transferase
FOB88_RS14660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOB88_RS14665	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FOB88_RS14675	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOB88_RS14680	COG3107	peptidoglycan biosynthetic process
FOB88_RS14685	COG0792	nuclease activity
FOB88_RS14695	COG2823	Periplasmic or secreted lipoprotein
FOB88_RS14700	COG1741	Belongs to the pirin family
FOB88_RS14705	COG0583	DNA-binding transcription factor activity
FOB88_RS14710	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB88_RS14725	COG3964	amidohydrolase
FOB88_RS14755	COG1349	DNA-binding transcription factor activity
FOB88_RS14760	COG3783	Cytochrome b(562)
FOB88_RS14765	COG0312	modulator of DNA gyrase
FOB88_RS14775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB88_RS14780	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FOB88_RS14785	COG0840	transmembrane signaling receptor activity
FOB88_RS14795	COG2707	UPF0756 membrane protein
FOB88_RS14810	COG2105	PFAM AIG2 family protein
FOB88_RS14815	COG2911	Protein conserved in bacteria
FOB88_RS14820	COG0729	surface antigen
FOB88_RS14830	COG1253	flavin adenine dinucleotide binding
FOB88_RS14840	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FOB88_RS14845	COG1218	3'(2'),5'-bisphosphate nucleotidase
FOB88_RS14855	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB88_RS14860	COG3061	Opacity-associated protein A
FOB88_RS14870	COG0359	binds to the 23S rRNA
FOB88_RS14875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOB88_RS14880	COG2965	DNA replication, synthesis of RNA primer
FOB88_RS14885	COG0360	Binds together with S18 to 16S ribosomal RNA
FOB88_RS14890	COG1073	alpha beta
FOB88_RS14895	COG0840	transmembrane signaling receptor activity
FOB88_RS14900	COG3650	response to hydrogen peroxide
FOB88_RS14905	COG1960	acyl-CoA dehydrogenase activity
FOB88_RS14910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB88_RS14915	COG0557	exoribonuclease II activity
FOB88_RS14925	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOB88_RS14930	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FOB88_RS14935	COG0330	HflC and HflK could
FOB88_RS14940	COG0330	HflC and HflK could
FOB88_RS14945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOB88_RS14955	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOB88_RS14960	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOB88_RS14970	COG0802	atpase or kinase
FOB88_RS14975	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOB88_RS14975	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOB88_RS14980	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOB88_RS15000	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOB88_RS15005	COG1162	GTPase activity
FOB88_RS15010	COG0688	phosphatidylethanolamine metabolic process
FOB88_RS15015	COG3264	Mechanosensitive ion channel
FOB88_RS15015	COG1511	domain protein
FOB88_RS15020	COG0039	L-malate dehydrogenase activity
FOB88_RS15025	COG1438	arginine binding
FOB88_RS15050	COG2732	(Barnase) inhibitor
FOB88_RS15055	COG1012	belongs to the aldehyde dehydrogenase family
FOB88_RS15060	COG1289	transmembrane transporter activity
FOB88_RS15065	COG1566	PFAM secretion protein HlyD family protein
FOB88_RS15075	COG0583	DNA-binding transcription factor activity
FOB88_RS15080	COG0312	modulator of DNA gyrase
FOB88_RS15085	COG3164	Protein of unknown function
FOB88_RS15090	COG1530	ribonuclease E activity
FOB88_RS15100	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOB88_RS15105	COG1792	Involved in formation and maintenance of cell shape
FOB88_RS15110	COG1077	Cell shape determining protein MreB Mrl
FOB88_RS15115	COG2199	diguanylate cyclase activity
FOB88_RS15115	COG2200	EAL domain
FOB88_RS15120	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOB88_RS15130	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOB88_RS15135	COG0511	ligase activity, forming carbon-carbon bonds
FOB88_RS15140	COG0439	Biotin carboxylase
FOB88_RS15145	COG3924	membrane
FOB88_RS15150	COG4145	pantothenate transmembrane transporter activity
FOB88_RS15155	COG2264	protein methyltransferase activity
FOB88_RS15165	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FOB88_RS15170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB88_RS15175	COG4597	amino acid ABC transporter
FOB88_RS15180	COG0765	amino acid transport
FOB88_RS15185	COG1126	abc transporter atp-binding protein
FOB88_RS15220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOB88_RS15240	COG0551	DNA topoisomerase type I activity
FOB88_RS15250	COG0758	DNA mediated transformation
FOB88_RS15260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOB88_RS15265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB88_RS15265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB88_RS15270	COG0569	domain protein
FOB88_RS15275	COG1970	mechanosensitive ion channel activity
FOB88_RS15290	COG0203	ribosomal protein L17
FOB88_RS15305	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOB88_RS15310	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOB88_RS15315	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOB88_RS15320	COG0201	protein transport
FOB88_RS15325	COG0200	Binds to the 23S rRNA
FOB88_RS15330	COG1841	ribosomal large subunit assembly
FOB88_RS15335	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOB88_RS15340	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOB88_RS15355	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOB88_RS15370	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOB88_RS15385	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOB88_RS15400	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOB88_RS15405	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOB88_RS15415	COG0088	Forms part of the polypeptide exit tunnel
FOB88_RS15425	COG0051	transcription antitermination factor activity, RNA binding
FOB88_RS15450	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOB88_RS15455	COG0049	tRNA binding
FOB88_RS15460	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOB88_RS15470	COG2923	Belongs to the DsrF TusC family
FOB88_RS15480	COG2964	Protein conserved in bacteria
FOB88_RS15485	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB88_RS15490	COG2900	Belongs to the SlyX family
FOB88_RS15495	COG1047	Peptidyl-prolyl cis-trans
FOB88_RS15500	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FOB88_RS15505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB88_RS15505	COG0475	glutathione-regulated potassium exporter activity
FOB88_RS15510	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB88_RS15515	COG0488	(ABC) transporter
FOB88_RS15520	COG2175	clavaminate synthase activity
FOB88_RS15525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB88_RS15530	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FOB88_RS15535	COG4521	taurine ABC transporter
FOB88_RS15540	COG1609	Transcriptional regulator
FOB88_RS15550	COG0429	hydrolase of the alpha beta-hydrolase fold
FOB88_RS15560	COG3954	Phosphoribulokinase
FOB88_RS15565	COG1765	OsmC-like protein
FOB88_RS15575	COG1289	transmembrane transporter activity
FOB88_RS15605	COG0738	Major facilitator superfamily
FOB88_RS15610	COG0402	S-adenosylhomocysteine deaminase activity
FOB88_RS15620	COG0546	phosphoglycolate phosphatase activity
FOB88_RS15625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOB88_RS15635	COG3266	domain, Protein
FOB88_RS15640	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOB88_RS15645	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOB88_RS15650	COG4796	Type ii and iii secretion system protein
FOB88_RS15675	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOB88_RS15680	COG0494	nUDIX hydrolase
FOB88_RS15690	COG1011	Hydrolase
FOB88_RS15695	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOB88_RS15700	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOB88_RS15705	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FOB88_RS15715	COG0745	RESPONSE REGULATOR receiver
FOB88_RS15725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB88_RS15730	COG2183	response to ionizing radiation
FOB88_RS15735	COG0366	Alpha amylase catalytic
FOB88_RS15750	COG1040	competence protein
FOB88_RS15755	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOB88_RS15755	COG0316	Belongs to the HesB IscA family
FOB88_RS15760	COG1640	4-alpha-glucanotransferase
FOB88_RS15765	COG0058	SHG alpha-glucan phosphorylase activity
FOB88_RS15770	COG1349	DNA-binding transcription factor activity
FOB88_RS15780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB88_RS15785	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOB88_RS15790	COG0058	SHG alpha-glucan phosphorylase activity
FOB88_RS15795	COG0297	glycogen (starch) synthase activity
FOB88_RS15805	COG1523	belongs to the glycosyl hydrolase 13 family
FOB88_RS15820	COG2095	MarC family integral membrane protein
FOB88_RS15825	COG2610	gluconate transmembrane transporter activity
FOB88_RS15830	COG3265	gluconokinase activity
FOB88_RS15835	COG1609	Transcriptional regulator
FOB88_RS15840	COG1741	Belongs to the pirin family
FOB88_RS15845	COG1247	-acetyltransferase
FOB88_RS15850	COG0405	Gamma-glutamyltransferase
FOB88_RS15860	COG0584	glycerophosphoryl diester phosphodiesterase
FOB88_RS15880	COG1653	transport
FOB88_RS15905	COG0683	leucine binding
FOB88_RS15915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOB88_RS15920	COG2177	Part of the ABC transporter FtsEX involved in
FOB88_RS15925	COG2884	Cell division ATP-binding protein ftsE
FOB88_RS15930	COG0552	protein localization to endoplasmic reticulum
FOB88_RS15930	COG0552	protein localization to endoplasmic reticulum
FOB88_RS15935	COG0742	ribosomal rna small subunit methyltransferase
FOB88_RS15940	COG3776	membrane
FOB88_RS15950	COG3714	YhhN family
FOB88_RS15965	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOB88_RS15975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB88_RS15980	COG3962	Belongs to the TPP enzyme family
FOB88_RS15985	COG0673	inositol 2-dehydrogenase activity
FOB88_RS15990	COG1082	Xylose isomerase domain protein TIM barrel
FOB88_RS16000	COG3718	enzyme involved in inositol metabolism
FOB88_RS16010	COG2233	PERMEase
FOB88_RS16015	COG0628	permease
FOB88_RS16020	COG2186	Transcriptional regulator
FOB88_RS16025	COG1312	Catalyzes the dehydration of D-mannonate
FOB88_RS16030	COG2200	EAL domain
FOB88_RS16045	COG0113	porphobilinogen synthase activity
FOB88_RS16055	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOB88_RS16060	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS16080	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FOB88_RS16085	COG0747	negative chemotaxis
FOB88_RS16090	COG0601	transmembrane transport
FOB88_RS16095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB88_RS16100	COG0444	Belongs to the ABC transporter superfamily
FOB88_RS16105	COG4608	Belongs to the ABC transporter superfamily
FOB88_RS16115	COG2081	HI0933 family
FOB88_RS16120	COG0306	phosphate transporter
FOB88_RS16135	COG0742	ribosomal rna small subunit methyltransferase
FOB88_RS16145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOB88_RS16155	COG1234	tRNA 3'-trailer cleavage
FOB88_RS16160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB88_RS16165	COG1940	carbohydrate kinase activity
FOB88_RS16170	COG0483	inositol monophosphate 1-phosphatase activity
FOB88_RS16175	COG3842	ATPase activity
FOB88_RS16195	COG0584	glycerophosphoryl diester phosphodiesterase
FOB88_RS16220	COG2814	Major facilitator Superfamily
FOB88_RS16225	COG0583	DNA-binding transcription factor activity
FOB88_RS16230	COG2862	Uncharacterized protein family, UPF0114
FOB88_RS16235	COG2205	protein histidine kinase activity
FOB88_RS16240	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FOB88_RS16245	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FOB88_RS16250	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FOB88_RS16270	COG1132	(ABC) transporter
FOB88_RS16280	COG0400	carboxylic ester hydrolase activity
FOB88_RS16285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOB88_RS16300	COG1063	alcohol dehydrogenase
FOB88_RS16305	COG1802	Transcriptional regulator
FOB88_RS16310	COG2271	Major facilitator Superfamily
FOB88_RS16325	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOB88_RS16335	COG1971	Probably functions as a manganese efflux pump
FOB88_RS16355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB88_RS16360	COG0625	glutathione transferase activity
FOB88_RS16370	COG0300	oxidoreductase activity
FOB88_RS16375	COG0583	DNA-binding transcription factor activity
FOB88_RS16380	COG1295	ribonuclease BN
FOB88_RS16385	COG0477	Major facilitator Superfamily
FOB88_RS16390	COG0583	DNA-binding transcription factor activity
FOB88_RS16395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB88_RS16410	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS16415	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOB88_RS16440	COG0129	dihydroxy-acid dehydratase activity
FOB88_RS16450	COG3978	acetolactate synthase activity
FOB88_RS16470	COG3085	chromosome segregation
FOB88_RS16475	COG0583	DNA-binding transcription factor activity
FOB88_RS16520	COG4206	TonB-dependent receptor
FOB88_RS16540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB88_RS16550	COG0165	Argininosuccinate lyase
FOB88_RS16555	COG0137	argininosuccinate synthase activity
FOB88_RS16570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB88_RS16575	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOB88_RS16580	COG0840	transmembrane signaling receptor activity
FOB88_RS16590	COG0527	aspartate kinase activity
FOB88_RS16590	COG0460	homoserine dehydrogenase
FOB88_RS16595	COG0626	cystathionine gamma-synthase activity
FOB88_RS16600	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FOB88_RS16605	COG0254	rRNA binding
FOB88_RS16610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOB88_RS16615	COG1609	Transcriptional regulator
FOB88_RS16620	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOB88_RS16625	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FOB88_RS16635	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOB88_RS16640	COG3074	FtsZ-dependent cytokinesis
FOB88_RS16645	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB88_RS16650	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOB88_RS16655	COG1494	fructose-1,6-bisphosphatase
FOB88_RS16660	COG2814	Major facilitator Superfamily
FOB88_RS16670	COG3152	Membrane
FOB88_RS16680	COG0149	triose-phosphate isomerase activity
FOB88_RS16695	COG0205	6-phosphofructokinase activity
FOB88_RS16705	COG3729	General stress protein
FOB88_RS16710	COG3678	ATP-independent chaperone mediated protein folding
FOB88_RS16715	COG0745	RESPONSE REGULATOR receiver
FOB88_RS16720	COG2205	protein histidine kinase activity
FOB88_RS16725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOB88_RS16735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOB88_RS16740	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FOB88_RS16745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB88_RS16750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB88_RS16755	COG4942	peptidase
FOB88_RS16760	COG2861	carbohydrate metabolic process
FOB88_RS16770	COG0156	8-amino-7-oxononanoate synthase activity
FOB88_RS16775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB88_RS16780	COG0859	PFAM glycosyl transferase family 9
FOB88_RS16785	COG0859	PFAM glycosyl transferase family 9
FOB88_RS16795	COG3307	-O-antigen
FOB88_RS16800	COG1216	Glycosyl transferase, family 2
FOB88_RS16800	COG1442	glycosyl transferase family 8
FOB88_RS16810	COG0438	transferase activity, transferring glycosyl groups
FOB88_RS16820	COG1216	Glycosyl transferase, family 2
FOB88_RS16825	COG0859	PFAM glycosyl transferase family 9
FOB88_RS16835	COG1519	Transferase
FOB88_RS16850	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOB88_RS16865	COG2003	Belongs to the UPF0758 family
FOB88_RS16870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOB88_RS16880	COG1309	transcriptional regulator
FOB88_RS16890	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOB88_RS16895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB88_RS16905	COG1561	YicC-like family, N-terminal region
FOB88_RS16925	COG1560	Kdo2-lipid A biosynthetic process
FOB88_RS16930	COG2244	polysaccharide biosynthetic process
FOB88_RS16935	COG2860	membrane
FOB88_RS16950	COG1758	RNA polymerase activity
FOB88_RS16955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB88_RS16960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB88_RS16965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOB88_RS16970	COG2233	PERMEase
FOB88_RS16975	COG2982	Protein involved in outer membrane biogenesis
FOB88_RS16980	COG0456	acetyltransferase
FOB88_RS16995	COG1011	Hydrolase
FOB88_RS17010	COG3852	Histidine kinase
FOB88_RS17025	COG3078	GTPase activator activity
FOB88_RS17035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB88_RS17035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB88_RS17040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB88_RS17045	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOB88_RS17050	COG3084	Protein conserved in bacteria
FOB88_RS17060	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOB88_RS17085	COG0477	Major facilitator Superfamily
FOB88_RS17090	COG1609	Transcriptional regulator
FOB88_RS17095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB88_RS17105	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS17110	COG1129	ABC transporter
FOB88_RS17120	COG3111	PFAM Bacterial OB fold (BOF) protein
FOB88_RS17125	COG0745	RESPONSE REGULATOR receiver
FOB88_RS17130	COG0642	Histidine kinase
FOB88_RS17145	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FOB88_RS17150	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FOB88_RS17155	COG1522	sequence-specific DNA binding
FOB88_RS17160	COG0716	FMN binding
FOB88_RS17170	COG0357	Ribosomal RNA small subunit methyltransferase G
FOB88_RS17175	COG3312	ion transport
FOB88_RS17180	COG0356	it plays a direct role in the translocation of protons across the membrane
FOB88_RS17190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOB88_RS17195	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOB88_RS17200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOB88_RS17205	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOB88_RS17210	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOB88_RS17220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOB88_RS17225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOB88_RS17235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOB88_RS17240	COG0573	inorganic phosphate transmembrane transporter activity
FOB88_RS17245	COG0581	inorganic phosphate transmembrane transporter activity
FOB88_RS17250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB88_RS17255	COG0704	Plays a role in the regulation of phosphate uptake
FOB88_RS17260	COG2814	Major facilitator Superfamily
FOB88_RS17265	COG1070	Carbohydrate kinase
FOB88_RS17270	COG2115	Belongs to the xylose isomerase family
FOB88_RS17275	COG4213	ABC transporter substrate-binding protein
FOB88_RS17285	COG4214	carbohydrate transport
FOB88_RS17290	COG1609	Transcriptional regulator
FOB88_RS17290	COG2207	Transcriptional regulator
FOB88_RS17310	COG1129	ABC transporter
FOB88_RS17315	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS17320	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS17325	COG1737	Transcriptional regulator
FOB88_RS17360	COG0583	DNA-binding transcription factor activity
FOB88_RS17375	COG4580	involved in the transport of maltose and maltodextrins
FOB88_RS17380	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOB88_RS17385	COG2723	6-phospho-beta-galactosidase activity
FOB88_RS17390	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB88_RS17390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB88_RS17395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB88_RS17400	COG1609	Transcriptional regulator
FOB88_RS17405	COG1940	carbohydrate kinase activity
FOB88_RS17410	COG1484	DNA-dependent DNA replication
FOB88_RS17425	COG2818	Glycosylase
FOB88_RS17430	COG2885	chlorophyll binding
FOB88_RS17440	COG1609	Transcriptional regulator
FOB88_RS17450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB88_RS17465	COG3977	Valine--pyruvate aminotransferase
FOB88_RS17490	COG5645	(Lipo)protein
FOB88_RS17495	COG0823	Involved in the tonB-independent uptake of proteins
FOB88_RS17500	COG0561	phosphatase activity
FOB88_RS17505	COG0187	DNA topoisomerase II activity
FOB88_RS17510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOB88_RS17515	COG0592	DNA-directed DNA polymerase activity
FOB88_RS17520	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOB88_RS17530	COG0594	ribonuclease P activity
FOB88_RS17540	COG0706	membrane insertase activity
FOB88_RS17545	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOB88_RS17550	COG0778	Nitroreductase
FOB88_RS17560	COG2252	PERMEase
FOB88_RS17565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB88_RS17570	COG3274	enterobacterial common antigen metabolic process
FOB88_RS17575	COG0752	glycyl-tRNA synthetase alpha subunit
FOB88_RS17580	COG0751	glycine-tRNA ligase activity
FOB88_RS17595	COG0625	glutathione transferase activity
FOB88_RS17610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOB88_RS17615	COG2990	Protein conserved in bacteria
FOB88_RS17625	COG3722	fumarate hydratase activity
FOB88_RS17635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB88_RS17635	COG2213	PTS system mannitol-specific
FOB88_RS17645	COG2944	sequence-specific DNA binding
FOB88_RS17650	COG0814	amino acid
FOB88_RS17670	COG1846	Transcriptional regulator
FOB88_RS17675	COG1764	response to oxidative stress
FOB88_RS17700	COG0747	negative chemotaxis
FOB88_RS17705	COG0601	transmembrane transport
FOB88_RS17710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB88_RS17715	COG0444	Belongs to the ABC transporter superfamily
FOB88_RS17720	COG4608	Belongs to the ABC transporter superfamily
FOB88_RS17730	COG0455	bacterial-type flagellum organization
FOB88_RS17735	COG1215	transferase activity, transferring glycosyl groups
FOB88_RS17755	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOB88_RS17760	COG2200	EAL domain
FOB88_RS17760	COG2199	diguanylate cyclase activity
FOB88_RS17770	COG0612	Peptidase, M16
FOB88_RS17785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB88_RS17790	COG2200	EAL domain
FOB88_RS17795	COG2982	Protein involved in outer membrane biogenesis
FOB88_RS17800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB88_RS17810	COG0248	Ppx GppA phosphatase
FOB88_RS17815	COG0513	Belongs to the DEAD box helicase family
FOB88_RS17820	COG3118	belongs to the thioredoxin family
FOB88_RS17825	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOB88_RS17830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB88_RS17835	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FOB88_RS17840	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOB88_RS17845	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOB88_RS17850	COG0456	acetyltransferase
FOB88_RS17855	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOB88_RS17860	COG2244	polysaccharide biosynthetic process
FOB88_RS17875	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FOB88_RS17910	COG3071	HemY protein
FOB88_RS17915	COG2959	enzyme of heme biosynthesis
FOB88_RS17925	COG0181	hydroxymethylbilane synthase activity
FOB88_RS17940	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOB88_RS17955	COG1011	Hydrolase
FOB88_RS17960	COG0210	DNA helicase
FOB88_RS17970	COG3180	Ammonia monooxygenase
FOB88_RS17980	COG1733	regulation of RNA biosynthetic process
FOB88_RS17990	COG2050	protein possibly involved in aromatic compounds catabolism
FOB88_RS18005	COG1280	lysine exporter protein (LysE YggA)
FOB88_RS18010	COG1280	lysine exporter protein (LysE YggA)
FOB88_RS18015	COG2267	carboxylic ester hydrolase activity
FOB88_RS18020	COG0561	phosphatase activity
FOB88_RS18025	COG2271	Major facilitator Superfamily
FOB88_RS18035	COG4807	Protein conserved in bacteria
FOB88_RS18040	COG0583	DNA-binding transcription factor activity
FOB88_RS18045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB88_RS18050	COG0412	Dienelactone hydrolase
FOB88_RS18055	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FOB88_RS18060	COG1322	Protein conserved in bacteria
FOB88_RS18065	COG2226	methyltransferase
FOB88_RS18075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOB88_RS18085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB88_RS18090	COG0805	protein transport
FOB88_RS18095	COG0084	hydrolase, TatD family'
FOB88_RS18105	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOB88_RS18110	COG0543	2 iron, 2 sulfur cluster binding
FOB88_RS18115	COG0183	Belongs to the thiolase family
FOB88_RS18125	COG0006	proline dipeptidase activity
FOB88_RS18130	COG1739	Uncharacterized protein family UPF0029
FOB88_RS18165	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOB88_RS18170	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FOB88_RS18170	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FOB88_RS18205	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOB88_RS18210	COG0250	Participates in transcription elongation, termination and antitermination
FOB88_RS18215	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOB88_RS18220	COG0081	regulation of translation
FOB88_RS18225	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOB88_RS18230	COG0222	ribosome binding
FOB88_RS18235	COG0085	RNA polymerase activity
FOB88_RS18240	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOB88_RS18250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB88_RS18260	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FOB88_RS18265	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FOB88_RS18270	COG2816	NAD+ diphosphatase activity
FOB88_RS18275	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOB88_RS18305	COG0138	bifunctional purine biosynthesis protein purh
FOB88_RS18350	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FOB88_RS18355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOB88_RS18370	COG2186	Transcriptional regulator
FOB88_RS18395	COG1410	methionine synthase
FOB88_RS18395	COG0646	methionine synthase
FOB88_RS18400	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB88_RS18425	COG0527	aspartate kinase activity
FOB88_RS18445	COG3223	Belongs to the PsiE family
FOB88_RS18460	COG3385	transposase activity
FOB88_RS18470	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOB88_RS18475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOB88_RS18480	COG0534	Mate efflux family protein
FOB88_RS18490	COG0735	belongs to the Fur family
FOB88_RS18500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB88_RS18520	COG1522	sequence-specific DNA binding
FOB88_RS18530	COG1448	Aminotransferase
FOB88_RS18540	COG2315	Protein conserved in bacteria
FOB88_RS18545	COG1064	alcohol dehydrogenase
FOB88_RS18555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOB88_RS18560	COG0629	single-stranded DNA binding
FOB88_RS18600	COG2207	Transcriptional regulator
FOB88_RS18605	COG0789	Transcriptional regulator
FOB88_RS18615	COG2252	PERMEase
FOB88_RS18620	COG0025	NhaP-type Na H and K H
FOB88_RS18625	COG0583	DNA-binding transcription factor activity
FOB88_RS18635	COG1346	cytolysis
FOB88_RS18645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB88_RS18650	COG3162	membrane
FOB88_RS18660	COG1301	dicarboxylic acid transport
FOB88_RS18665	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOB88_RS18675	COG0840	transmembrane signaling receptor activity
FOB88_RS18680	COG2207	Transcriptional regulator
FOB88_RS18695	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FOB88_RS18720	COG0840	transmembrane signaling receptor activity
FOB88_RS18730	COG3248	Nucleoside-binding outer membrane protein
FOB88_RS18735	COG0642	Histidine kinase
FOB88_RS18740	COG0745	RESPONSE REGULATOR receiver
FOB88_RS18745	COG4977	sequence-specific DNA binding
FOB88_RS18755	COG2814	Major facilitator Superfamily
FOB88_RS18760	COG4993	Dehydrogenase
FOB88_RS18775	COG2971	BadF BadG BcrA BcrD
FOB88_RS18800	COG1175	transmembrane transport
FOB88_RS18805	COG0395	ABC-type sugar transport system, permease component
FOB88_RS18815	COG0473	3-isopropylmalate dehydrogenase activity
FOB88_RS18825	COG0840	transmembrane signaling receptor activity
FOB88_RS18835	COG0625	glutathione transferase activity
FOB88_RS18850	COG2223	nitrite transmembrane transporter activity
FOB88_RS18875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB88_RS18890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB88_RS18890	COG3453	Protein conserved in bacteria
FOB88_RS18900	COG1252	NADH dehydrogenase
FOB88_RS18910	COG3479	Phenolic acid decarboxylase
FOB88_RS18960	COG0840	transmembrane signaling receptor activity
FOB88_RS18965	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOB88_RS18970	COG3477	response to acidic pH
FOB88_RS18975	COG0235	Class ii aldolase
FOB88_RS18980	COG3623	hexulose-6-phosphate isomerase
FOB88_RS18985	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FOB88_RS18990	COG1070	Carbohydrate kinase
FOB88_RS19000	COG2731	YhcH YjgK YiaL family protein
FOB88_RS19020	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS19025	COG1129	ABC transporter
FOB88_RS19030	COG1414	Transcriptional regulator
FOB88_RS19055	COG0667	Aldo Keto reductase
FOB88_RS19060	COG2382	esterase
FOB88_RS19060	COG3507	Belongs to the glycosyl hydrolase 43 family
FOB88_RS19060	COG3693	PFAM glycoside hydrolase, family 10
FOB88_RS19070	COG3385	transposase activity
FOB88_RS19075	COG1278	Cold shock
FOB88_RS19080	COG1918	ferrous iron import across plasma membrane
FOB88_RS19085	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOB88_RS19090	COG1216	Glycosyl transferase, family 2
FOB88_RS19100	COG1442	glycosyl transferase family 8
FOB88_RS19100	COG1216	Glycosyl transferase, family 2
FOB88_RS19125	COG1309	transcriptional regulator
FOB88_RS19135	COG1324	tolerance protein
FOB88_RS19140	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOB88_RS19150	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOB88_RS19155	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOB88_RS19170	COG1509	lysine 2,3-aminomutase activity
FOB88_RS19175	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOB88_RS19185	COG5510	response to toxic substance
FOB88_RS19195	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FOB88_RS19200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB88_RS19205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB88_RS19210	COG3105	Protein conserved in bacteria
FOB88_RS19215	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOB88_RS19220	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOB88_RS19225	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOB88_RS19230	COG0625	glutathione transferase activity
FOB88_RS19235	COG2969	positive regulation of protein catabolic process
FOB88_RS19240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOB88_RS19245	COG0067	glutamate synthase
FOB88_RS19245	COG0069	glutamate synthase activity
FOB88_RS19245	COG0070	glutamate synthase
FOB88_RS19250	COG5002	protein histidine kinase activity
FOB88_RS19250	COG2198	Histidine kinase
FOB88_RS19250	COG0784	Response regulator, receiver
FOB88_RS19260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB88_RS19265	COG1660	Displays ATPase and GTPase activities
FOB88_RS19280	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOB88_RS19285	COG1137	ATPase activity
FOB88_RS19290	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FOB88_RS19295	COG3117	lipopolysaccharide transmembrane transporter activity
FOB88_RS19300	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOB88_RS19305	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOB88_RS19305	COG0517	IMP dehydrogenase activity
FOB88_RS19310	COG0530	calcium, potassium:sodium antiporter activity
FOB88_RS19315	COG1127	ABC transporter
FOB88_RS19320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOB88_RS19325	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOB88_RS19330	COG2854	intermembrane phospholipid transfer
FOB88_RS19335	COG3113	response to antibiotic
FOB88_RS19340	COG5007	Belongs to the BolA IbaG family
FOB88_RS19350	COG3423	Transcriptional regulator
FOB88_RS19355	COG0142	geranyltranstransferase activity
FOB88_RS19360	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOB88_RS19370	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOB88_RS19380	COG2027	D-alanyl-D-alanine carboxypeptidase
FOB88_RS19390	COG1534	Rna-binding protein
FOB88_RS19395	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FOB88_RS19405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOB88_RS19410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB88_RS19415	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOB88_RS19430	COG0779	Required for maturation of 30S ribosomal subunits
FOB88_RS19435	COG0195	Participates in both transcription termination and antitermination
FOB88_RS19445	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOB88_RS19455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOB88_RS19460	COG1185	polyribonucleotide nucleotidyltransferase activity
FOB88_RS19475	COG0513	Belongs to the DEAD box helicase family
FOB88_RS19480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB88_RS19485	COG0826	peptidase U32
FOB88_RS19490	COG0826	peptidase U32
FOB88_RS19495	COG3154	lipid carrier protein
FOB88_RS19500	COG3153	acetyltransferase
FOB88_RS19505	COG2827	Endonuclease containing a URI domain
FOB88_RS19515	COG0693	protein deglycase activity
FOB88_RS19520	COG0702	epimerase
FOB88_RS19535	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOB88_RS19540	COG1609	Transcriptional regulator
FOB88_RS19550	COG0768	penicillin binding
FOB88_RS19575	COG0204	Acyl-transferase
FOB88_RS19575	COG0318	PFAM AMP-dependent synthetase and ligase
FOB88_RS19590	COG1335	isochorismatase
FOB88_RS19600	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FOB88_RS19610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOB88_RS19615	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FOB88_RS19625	COG0456	acetyltransferase
FOB88_RS19635	COG2927	DNA polymerase III (CHI subunit)
FOB88_RS19640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOB88_RS19645	COG0795	lipopolysaccharide-transporting ATPase activity
FOB88_RS19650	COG0795	lipopolysaccharide-transporting ATPase activity
FOB88_RS19670	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS19675	COG1129	ABC transporter
FOB88_RS19680	COG1609	Transcriptional regulator
FOB88_RS19700	COG2733	membrane
FOB88_RS19720	COG0433	COG0433 Predicted ATPase
FOB88_RS19755	COG0582	viral genome integration into host DNA
FOB88_RS19865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB88_RS19865	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FOB88_RS19935	COG0028	Belongs to the TPP enzyme family
FOB88_RS19955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB88_RS19960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB88_RS19965	COG2731	YhcH YjgK YiaL family protein
FOB88_RS19970	COG2271	Major facilitator Superfamily
FOB88_RS20000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB88_RS20015	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB88_RS20020	COG0463	Glycosyl transferase, family 2
FOB88_RS20055	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS20060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB88_RS20075	COG2382	esterase
FOB88_RS20090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB88_RS20095	COG1830	Aldolase
FOB88_RS20100	COG1063	alcohol dehydrogenase
FOB88_RS20130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOB88_RS20140	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOB88_RS20145	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS20150	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FOB88_RS20180	COG1116	anion transmembrane transporter activity
FOB88_RS20190	COG4948	Mandelate Racemase Muconate Lactonizing
FOB88_RS20195	COG1028	Short-chain dehydrogenase reductase Sdr
FOB88_RS20200	COG1063	alcohol dehydrogenase
FOB88_RS20205	COG0477	Major facilitator Superfamily
FOB88_RS20215	COG3012	SEC-C Motif Domain Protein
FOB88_RS20215	COG3318	Belongs to the UPF0149 family
FOB88_RS20260	COG0477	Major facilitator Superfamily
FOB88_RS20265	COG1609	Transcriptional regulator
FOB88_RS20275	COG2814	Major facilitator Superfamily
FOB88_RS20280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB88_RS20285	COG3706	GGDEF domain
FOB88_RS20315	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FOB88_RS20325	COG1011	Hydrolase
FOB88_RS20330	COG3726	membrane protein affecting hemolysin expression
FOB88_RS20335	COG0560	Phosphoserine phosphatase
FOB88_RS20365	COG3121	Chaperone
FOB88_RS20380	COG3121	Chaperone
FOB88_RS20395	COG0488	(ABC) transporter
FOB88_RS20400	COG1349	DNA-binding transcription factor activity
FOB88_RS20405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB88_RS20415	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FOB88_RS20430	COG4774	siderophore transport
FOB88_RS20440	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FOB88_RS20450	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS20460	COG1802	Transcriptional regulator
FOB88_RS20465	COG0439	Biotin carboxylase
FOB88_RS20475	COG0741	lytic transglycosylase activity
FOB88_RS20480	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FOB88_RS20485	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOB88_RS20490	COG0406	alpha-ribazole phosphatase activity
FOB88_RS20495	COG3708	Transcriptional regulator
FOB88_RS20495	COG2207	Transcriptional regulator
FOB88_RS20500	COG3045	CreA protein
FOB88_RS20505	COG0745	RESPONSE REGULATOR receiver
FOB88_RS20510	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FOB88_RS20520	COG0527	aspartate kinase activity
FOB88_RS20520	COG0460	homoserine dehydrogenase
FOB88_RS20525	COG0083	homoserine kinase activity
FOB88_RS20535	COG3022	response to hydroperoxide
FOB88_RS20540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB88_RS20545	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOB88_RS20555	COG1584	GPR1 FUN34 yaaH family protein
FOB88_RS20565	COG0484	heat shock protein binding
FOB88_RS20575	COG0268	Binds directly to 16S ribosomal RNA
FOB88_RS20580	COG0196	riboflavin kinase activity
FOB88_RS20585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOB88_RS20590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOB88_RS20595	COG1047	Peptidyl-prolyl cis-trans
FOB88_RS20610	COG0505	Belongs to the CarA family
FOB88_RS20615	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOB88_RS20630	COG0583	DNA-binding transcription factor activity
FOB88_RS20650	COG2967	ApaG domain
FOB88_RS20655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOB88_RS20660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOB88_RS20665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB88_RS20670	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOB88_RS20680	COG0564	pseudouridine synthase activity
FOB88_RS20685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOB88_RS20690	COG0417	DNA replication proofreading
FOB88_RS20695	COG0586	Pfam SNARE associated Golgi protein
FOB88_RS20700	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FOB88_RS20705	COG1178	ABC-type Fe3 transport system permease component
FOB88_RS20710	COG4143	(ABC) transporter
FOB88_RS20720	COG2814	Major facilitator Superfamily
FOB88_RS20725	COG2271	Major facilitator Superfamily
FOB88_RS20730	COG0583	DNA-binding transcription factor activity
FOB88_RS20740	COG0738	Major facilitator superfamily
FOB88_RS20760	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOB88_RS20770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB88_RS20780	COG0028	Belongs to the TPP enzyme family
FOB88_RS20795	COG2001	Belongs to the MraZ family
FOB88_RS20805	COG3116	cell division
FOB88_RS20810	COG0768	penicillin binding
FOB88_RS20820	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB88_RS20830	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOB88_RS20835	COG0772	Belongs to the SEDS family
FOB88_RS20850	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOB88_RS20860	COG0849	cell division
FOB88_RS20865	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOB88_RS20885	COG0494	nUDIX hydrolase
FOB88_RS20900	COG0237	dephospho-CoA kinase activity
FOB88_RS20905	COG0516	GMP reductase activity
FOB88_RS20910	COG1459	type II secretion system
FOB88_RS20915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB88_RS20920	COG4969	Belongs to the N-Me-Phe pilin family
FOB88_RS20930	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOB88_RS20935	COG3725	Membrane protein required for beta-lactamase induction
FOB88_RS20940	COG3940	Belongs to the glycosyl hydrolase 43 family
FOB88_RS20945	COG2211	Major facilitator Superfamily
FOB88_RS20950	COG1113	amino acid transport
FOB88_RS20955	COG2186	Transcriptional regulator
FOB88_RS20960	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOB88_RS20965	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB88_RS20970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB88_RS20975	COG0583	DNA-binding transcription factor activity
FOB88_RS20980	COG0667	Aldo Keto reductase
FOB88_RS21005	COG0840	transmembrane signaling receptor activity
FOB88_RS21025	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOB88_RS21035	COG2132	Multicopper oxidase
FOB88_RS21045	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FOB88_RS21050	COG0288	reversible hydration of carbon dioxide
FOB88_RS21055	COG1131	(ABC) transporter
FOB88_RS21060	COG0842	Transport permease protein
FOB88_RS21065	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FOB88_RS21070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOB88_RS21080	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOB88_RS21095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOB88_RS21100	COG1489	DNA binding
FOB88_RS21105	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOB88_RS21110	COG1643	Atp-dependent helicase
FOB88_RS21115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB88_RS21120	COG4774	siderophore transport
FOB88_RS21125	COG1120	ATPase activity
FOB88_RS21130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB88_RS21145	COG0316	Belongs to the HesB IscA family
FOB88_RS21160	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB88_RS21170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB88_RS21175	COG3835	regulator
FOB88_RS21190	COG2171	N-acyltransferase activity
FOB88_RS21195	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOB88_RS21215	COG0528	UMP kinase activity
FOB88_RS21225	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOB88_RS21230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOB88_RS21235	COG0575	Belongs to the CDS family
FOB88_RS21245	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB88_RS21250	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FOB88_RS21260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB88_RS21270	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB88_RS21275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOB88_RS21295	COG0346	lactoylglutathione lyase activity
FOB88_RS21300	COG0037	tRNA processing
FOB88_RS21310	COG4568	rho-dependent transcription termination
FOB88_RS21325	COG3385	transposase activity
FOB88_RS21335	COG1720	tRNA m6t6A37 methyltransferase activity
FOB88_RS21350	COG2011	ABC-type metal ion transport system permease component
FOB88_RS21360	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOB88_RS21400	COG0477	Major facilitator Superfamily
FOB88_RS21405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB88_RS21410	COG1042	CoA-binding domain protein
FOB88_RS21410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB88_RS21410	COG0045	succinate-CoA ligase (ADP-forming) activity
FOB88_RS21420	COG3118	belongs to the thioredoxin family
FOB88_RS21425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB88_RS21430	COG1733	regulation of RNA biosynthetic process
FOB88_RS21435	COG1064	alcohol dehydrogenase
FOB88_RS21440	COG2814	Major facilitator Superfamily
FOB88_RS21445	COG1566	PFAM secretion protein HlyD family protein
FOB88_RS21450	COG1846	Transcriptional regulator
FOB88_RS21455	COG2814	Major facilitator Superfamily
FOB88_RS21465	COG4176	ABC-type proline glycine betaine transport system permease component
FOB88_RS21475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB88_RS21480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB88_RS21485	COG1780	Probably involved in ribonucleotide reductase function
FOB88_RS21490	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB88_RS21495	COG4575	ribosome binding
FOB88_RS21505	COG0833	amino acid
FOB88_RS21510	COG2040	homocysteine
FOB88_RS21520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB88_RS21530	COG0444	Belongs to the ABC transporter superfamily
FOB88_RS21535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB88_RS21540	COG0601	transmembrane transport
FOB88_RS21545	COG0747	negative chemotaxis
FOB88_RS21570	COG1120	ATPase activity
FOB88_RS21575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB88_RS21590	COG5002	protein histidine kinase activity
FOB88_RS21595	COG0745	RESPONSE REGULATOR receiver
FOB88_RS21610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB88_RS21630	COG0583	DNA-binding transcription factor activity
FOB88_RS21635	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB88_RS21645	COG1733	regulation of RNA biosynthetic process
FOB88_RS21650	COG0604	alcohol dehydrogenase
FOB88_RS21670	COG3386	PFAM SMP-30 Gluconolaconase
FOB88_RS21675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB88_RS21680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOB88_RS21685	COG1414	Transcriptional regulator
FOB88_RS21690	COG4604	ABC transporter, ATP-binding protein
FOB88_RS21695	COG4605	iron ion homeostasis
FOB88_RS21705	COG4607	ABC-type enterochelin transport system periplasmic component
FOB88_RS21710	COG4771	TonB-dependent receptor
FOB88_RS21750	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FOB88_RS21770	COG0582	viral genome integration into host DNA
FOB88_RS21785	COG2867	negative regulation of translational initiation
FOB88_RS21790	COG2914	Belongs to the UPF0125 (RnfH) family
FOB88_RS21795	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB88_RS21800	COG0497	DNA recombination
FOB88_RS21805	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOB88_RS21810	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOB88_RS21825	COG0513	Belongs to the DEAD box helicase family
FOB88_RS21835	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOB88_RS21850	COG3026	antisigma factor binding
FOB88_RS21855	COG3086	response to oxidative stress
FOB88_RS21860	COG0481	GTPase activity
FOB88_RS21870	COG0571	ribonuclease III activity
FOB88_RS21880	COG1381	Involved in DNA repair and RecF pathway recombination
FOB88_RS21885	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOB88_RS21890	COG0736	holo-[acyl-carrier-protein] synthase activity
FOB88_RS21895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB88_RS21900	COG1737	Transcriptional regulator
FOB88_RS21905	COG0560	Phosphoserine phosphatase
FOB88_RS21915	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOB88_RS21920	COG0047	phosphoribosylformylglycinamidine synthase activity
FOB88_RS21920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOB88_RS21925	COG2205	protein histidine kinase activity
FOB88_RS21930	COG3170	Tfp pilus assembly protein FimV
FOB88_RS21935	COG2204	response regulator
FOB88_RS21940	COG0347	Belongs to the P(II) protein family
FOB88_RS21955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOB88_RS21960	COG2814	Major facilitator Superfamily
FOB88_RS21965	COG3711	transcriptional antiterminator
FOB88_RS21975	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FOB88_RS21985	COG0483	inositol monophosphate 1-phosphatase activity
FOB88_RS21995	COG1959	2 iron, 2 sulfur cluster binding
FOB88_RS22005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOB88_RS22015	COG2897	thiosulfate sulfurtransferase activity
FOB88_RS22020	COG2373	Large extracellular alpha-helical protein
FOB88_RS22025	COG4953	penicillin-binding protein 1C
FOB88_RS22030	COG0105	UTP biosynthetic process
FOB88_RS22035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOB88_RS22045	COG1426	Protein conserved in bacteria
FOB88_RS22055	COG0124	histidyl-tRNA synthetase
FOB88_RS22060	COG2976	Protein conserved in bacteria
FOB88_RS22065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB88_RS22070	COG1160	GTP binding
FOB88_RS22075	COG1645	bacterial-type flagellum-dependent swarming motility
FOB88_RS22080	COG4993	Dehydrogenase
FOB88_RS22100	COG0517	IMP dehydrogenase activity
FOB88_RS22100	COG0516	GMP reductase activity
FOB88_RS22105	COG0519	Catalyzes the synthesis of GMP from XMP
FOB88_RS22105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOB88_RS22150	COG2239	Acts as a magnesium transporter
FOB88_RS22160	COG0500	methyltransferase
FOB88_RS22175	COG0573	inorganic phosphate transmembrane transporter activity
FOB88_RS22185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB88_RS22190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOB88_RS22195	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOB88_RS22210	COG2233	PERMEase
FOB88_RS22215	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOB88_RS22220	COG1393	Belongs to the ArsC family
FOB88_RS22225	COG4783	chaperone-mediated protein folding
FOB88_RS22230	COG1609	Transcriptional regulator
FOB88_RS22235	COG1840	ABC-type Fe3 transport system, periplasmic component
FOB88_RS22240	COG1178	ABC-type Fe3 transport system permease component
FOB88_RS22250	COG3842	ATPase activity
FOB88_RS22255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOB88_RS22260	COG3706	GGDEF domain
FOB88_RS22270	COG2211	Major facilitator Superfamily
FOB88_RS22280	COG0628	permease
FOB88_RS22285	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOB88_RS22290	COG2716	regulation of RNA biosynthetic process
FOB88_RS22295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB88_RS22300	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FOB88_RS22310	COG2321	neutral zinc metallopeptidase
FOB88_RS22315	COG1444	tRNA N-acetyltransferase activity
FOB88_RS22320	COG0400	carboxylic ester hydrolase activity
FOB88_RS22330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB88_RS22335	COG1393	Belongs to the ArsC family
FOB88_RS22345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB88_RS22350	COG2197	response regulator
FOB88_RS22355	COG3850	Histidine kinase
FOB88_RS22370	COG0494	nUDIX hydrolase
FOB88_RS22375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB88_RS22380	COG1940	carbohydrate kinase activity
FOB88_RS22385	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOB88_RS22390	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS22395	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS22400	COG1129	ABC transporter
FOB88_RS22410	COG1349	DNA-binding transcription factor activity
FOB88_RS22415	COG5342	invasion associated locus B
FOB88_RS22420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOB88_RS22435	COG3493	citrate carrier protein
FOB88_RS22440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOB88_RS22445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB88_RS22465	COG0456	acetyltransferase
FOB88_RS22485	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FOB88_RS22490	COG4208	sulfate ABC transporter
FOB88_RS22495	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FOB88_RS22500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOB88_RS22505	COG0745	RESPONSE REGULATOR receiver
FOB88_RS22510	COG2205	protein histidine kinase activity
FOB88_RS22520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB88_RS22550	COG3530	Putative quorum-sensing-regulated virulence factor
FOB88_RS22555	COG0385	Bile acid
FOB88_RS22560	COG0583	DNA-binding transcription factor activity
FOB88_RS22600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB88_RS22605	COG3415	Transposase
FOB88_RS22610	COG2116	formate transmembrane transporter activity
FOB88_RS22655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB88_RS22660	COG1914	H( )-stimulated, divalent metal cation uptake system
FOB88_RS22665	COG4122	O-methyltransferase activity
FOB88_RS22675	COG0667	Aldo Keto reductase
FOB88_RS22680	COG3961	Belongs to the TPP enzyme family
FOB88_RS22685	COG0837	glucose binding
FOB88_RS22690	COG3279	Response regulator of the LytR AlgR family
FOB88_RS22695	COG3275	phosphorelay sensor kinase activity
FOB88_RS22705	COG0436	Aminotransferase
FOB88_RS22750	COG2223	nitrite transmembrane transporter activity
FOB88_RS22785	COG3833	ABC-type maltose transport systems, permease component
FOB88_RS22790	COG3842	ATPase activity
FOB88_RS22795	COG0584	glycerophosphoryl diester phosphodiesterase
FOB88_RS22845	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOB88_RS22850	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOB88_RS22910	COG0582	viral genome integration into host DNA
FOB88_RS22920	COG2116	formate transmembrane transporter activity
FOB88_RS22930	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB88_RS22935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB88_RS22940	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB88_RS22945	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FOB88_RS22950	COG1138	Cytochrome C-type biogenesis protein
FOB88_RS22960	COG4235	cytochrome complex assembly
FOB88_RS22960	COG3088	subunit of a heme lyase
FOB88_RS22965	COG3088	subunit of a heme lyase
FOB88_RS22965	COG4235	cytochrome complex assembly
FOB88_RS22975	COG2067	long-chain fatty acid transport protein
FOB88_RS22980	COG3691	Protein conserved in bacteria
FOB88_RS22985	COG0183	Belongs to the thiolase family
FOB88_RS22995	COG2062	phosphohistidine phosphatase, SixA
FOB88_RS23000	COG0840	transmembrane signaling receptor activity
FOB88_RS23015	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOB88_RS23025	COG0730	response to heat
FOB88_RS23030	COG3101	peptidyl-lysine hydroxylation
FOB88_RS23045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB88_RS23055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB88_RS23085	COG0642	Histidine kinase
FOB88_RS23100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOB88_RS23110	COG0586	Pfam SNARE associated Golgi protein
FOB88_RS23120	COG0285	dihydrofolate synthase activity
FOB88_RS23125	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FOB88_RS23130	COG1286	toxin biosynthetic process
FOB88_RS23135	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOB88_RS23140	COG0163	prenyltransferase activity
FOB88_RS23150	COG4215	(ABC) transporter
FOB88_RS23155	COG4160	amino acid transport
FOB88_RS23160	COG4598	ABC transporter
FOB88_RS23170	COG0246	Mannitol dehydrogenase
FOB88_RS23175	COG1070	Carbohydrate kinase
FOB88_RS23185	COG1090	epimerase
FOB88_RS23190	COG0625	glutathione transferase activity
FOB88_RS23195	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FOB88_RS23200	COG0395	ABC-type sugar transport system, permease component
FOB88_RS23205	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOB88_RS23215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB88_RS23225	COG3842	ATPase activity
FOB88_RS23230	COG0857	belongs to the CobB CobQ family
FOB88_RS23230	COG0280	phosphate acetyltransferase
FOB88_RS23235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB88_RS23240	COG3092	negative regulation of chromosome organization
FOB88_RS23250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB88_RS23255	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FOB88_RS23260	COG0436	Aminotransferase
FOB88_RS23265	COG0583	DNA-binding transcription factor activity
FOB88_RS23280	COG0649	NAD binding
FOB88_RS23280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB88_RS23300	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FOB88_RS23310	COG0839	Belongs to the complex I subunit 6 family
FOB88_RS23315	COG0713	ATP synthesis coupled electron transport
FOB88_RS23320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOB88_RS23325	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB88_RS23330	COG1007	ATP synthesis coupled electron transport
FOB88_RS23340	COG2153	protein acetylation
FOB88_RS23350	COG4575	ribosome binding
FOB88_RS23360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB88_RS23365	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB88_RS23370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB88_RS23375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB88_RS23390	COG2197	response regulator
FOB88_RS23395	COG2198	Histidine kinase
FOB88_RS23395	COG0642	Histidine kinase
FOB88_RS23400	COG2223	nitrite transmembrane transporter activity
FOB88_RS23415	COG1132	(ABC) transporter
FOB88_RS23445	COG3145	DNA-N1-methyladenine dioxygenase activity
FOB88_RS23450	COG4615	Cyclic peptide transporter
FOB88_RS23460	COG0668	transmembrane transport
FOB88_RS23465	COG2211	Major facilitator Superfamily
FOB88_RS23500	COG1595	DNA-templated transcription, initiation
FOB88_RS23510	COG4178	(ABC) transporter
FOB88_RS23515	COG3118	belongs to the thioredoxin family
FOB88_RS23520	COG0312	modulator of DNA gyrase
FOB88_RS23525	COG0312	modulator of DNA gyrase
FOB88_RS23550	COG3311	Transcriptional regulator
FOB88_RS23635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB88_RS23640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB88_RS23670	COG0582	viral genome integration into host DNA
FOB88_RS23685	COG3082	Protein of unknown function (DUF1414)
FOB88_RS23690	COG3081	Nucleoid-associated protein
FOB88_RS23695	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOB88_RS23700	COG1061	Type III restriction enzyme res subunit
FOB88_RS23710	COG2814	Major facilitator Superfamily
FOB88_RS23720	COG4172	Belongs to the ABC transporter superfamily
FOB88_RS23725	COG4239	(ABC) transporter, permease
FOB88_RS23730	COG4174	ABC transporter (Permease)
FOB88_RS23735	COG4166	transmembrane transport
FOB88_RS23740	COG2200	EAL domain
FOB88_RS23745	COG0791	NLP P60 protein
FOB88_RS23750	COG0671	phosphoesterase, PA-phosphatase related
FOB88_RS23755	COG0523	cobalamin synthesis protein
FOB88_RS23760	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOB88_RS23770	COG0477	Major facilitator Superfamily
FOB88_RS23780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB88_RS23785	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOB88_RS23790	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB88_RS23790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB88_RS23795	COG1105	Belongs to the carbohydrate kinase PfkB family
FOB88_RS23800	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FOB88_RS23800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB88_RS23800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB88_RS23805	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FOB88_RS23815	COG2855	membrane
FOB88_RS23825	COG0583	DNA-binding transcription factor activity
FOB88_RS23830	COG0833	amino acid
FOB88_RS23835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB88_RS23840	COG1120	ATPase activity
FOB88_RS23855	COG0583	DNA-binding transcription factor activity
FOB88_RS23860	COG0477	Major facilitator Superfamily
FOB88_RS23870	COG2311	Membrane
FOB88_RS23895	COG2949	membrane
FOB88_RS23900	COG0281	malic enzyme
FOB88_RS23910	COG1346	cytolysis
FOB88_RS23915	COG1380	Effector of murein hydrolase LrgA
FOB88_RS23920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB88_RS23920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB88_RS23925	COG0489	protein tyrosine kinase activity
FOB88_RS23930	COG0456	acetyltransferase
FOB88_RS23940	COG3634	alkyl hydroperoxide reductase activity
FOB88_RS23965	COG1802	Transcriptional regulator
FOB88_RS23970	COG0246	Mannitol dehydrogenase
FOB88_RS23985	COG0745	RESPONSE REGULATOR receiver
FOB88_RS23990	COG2205	protein histidine kinase activity
FOB88_RS24000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB88_RS24010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB88_RS24015	COG0443	Heat shock 70 kDa protein
FOB88_RS24020	COG3447	MASE1 domain protein
FOB88_RS24020	COG5001	Diguanylate cyclase
FOB88_RS24020	COG5002	protein histidine kinase activity
FOB88_RS24030	COG0572	uridine kinase
FOB88_RS24035	COG0717	Belongs to the dCTP deaminase family
FOB88_RS24040	COG2982	Protein involved in outer membrane biogenesis
FOB88_RS24080	COG1216	Glycosyl transferase, family 2
FOB88_RS24080	COG0463	Glycosyl transferase, family 2
FOB88_RS24130	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOB88_RS24165	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FOB88_RS24170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB88_RS24175	COG1051	belongs to the nudix hydrolase family
FOB88_RS24180	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FOB88_RS24180	COG0662	Cupin 2, conserved barrel domain protein
FOB88_RS24185	COG1216	Glycosyl transferase, family 2
FOB88_RS24190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB88_RS24195	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOB88_RS24215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB88_RS24230	COG0140	phosphoribosyl-ATP diphosphatase activity
FOB88_RS24230	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOB88_RS24240	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOB88_RS24245	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOB88_RS24255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOB88_RS24260	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOB88_RS24265	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOB88_RS24275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB88_RS24280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB88_RS24285	COG1396	sequence-specific DNA binding
FOB88_RS24285	COG1917	Cupin 2, conserved barrel domain protein
FOB88_RS24290	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOB88_RS24295	COG0174	glutamine synthetase
FOB88_RS24300	COG0531	amino acid
FOB88_RS24305	COG1349	DNA-binding transcription factor activity
FOB88_RS24310	COG2084	Dehydrogenase
FOB88_RS24315	COG3395	kinase activity
FOB88_RS24320	COG0235	Class ii aldolase
FOB88_RS24325	COG3622	Belongs to the hyi family
FOB88_RS24330	COG2610	gluconate transmembrane transporter activity
FOB88_RS24335	COG2925	Exonuclease
FOB88_RS24345	COG1289	transmembrane transporter activity
FOB88_RS24350	COG2926	Belongs to the UPF0265 family
FOB88_RS24355	COG1609	Transcriptional regulator
FOB88_RS24360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOB88_RS24365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB88_RS24385	COG1012	belongs to the aldehyde dehydrogenase family
FOB88_RS24430	COG3468	outer membrane autotransporter barrel domain protein
FOB88_RS24445	COG0673	inositol 2-dehydrogenase activity
FOB88_RS24450	COG1216	Glycosyl transferase, family 2
FOB88_RS24450	COG1442	glycosyl transferase family 8
FOB88_RS24460	COG1309	transcriptional regulator
FOB88_RS24505	COG0318	PFAM AMP-dependent synthetase and ligase
FOB88_RS24515	COG0574	Belongs to the PEP-utilizing enzyme family
FOB88_RS24515	COG3848	Pyruvate phosphate dikinase
FOB88_RS24565	COG3851	Histidine kinase
FOB88_RS24590	COG1157	protein secretion by the type III secretion system
FOB88_RS24615	COG4794	Type iii secretion
FOB88_RS24625	COG4792	protein secretion
FOB88_RS24670	COG4669	(LipO)protein
FOB88_RS24710	COG1864	DNA RNA non-specific endonuclease
FOB88_RS24710	COG3591	Belongs to the peptidase S1B family
FOB88_RS24720	COG0840	transmembrane signaling receptor activity
FOB88_RS24740	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB88_RS24755	COG0583	DNA-binding transcription factor activity
FOB88_RS24805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB88_RS24820	COG1012	belongs to the aldehyde dehydrogenase family
FOB88_RS24830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB88_RS24840	COG0601	transmembrane transport
FOB88_RS24845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB88_RS24865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB88_RS24870	COG1473	amidohydrolase
FOB88_RS24880	COG1522	sequence-specific DNA binding
FOB88_RS24890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOB88_RS24895	COG1335	isochorismatase
FOB88_RS24900	COG2188	Transcriptional regulator
FOB88_RS24905	COG3624	Phosphonate C-P lyase system protein PhnG
FOB88_RS24910	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity