locus-tag	class	description
PSNIH2_RS00005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PSNIH2_RS00010	COG0629	single-stranded DNA binding
PSNIH2_RS00025	COG0306	phosphate transporter
PSNIH2_RS00030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PSNIH2_RS00035	COG0076	glutamate decarboxylase activity
PSNIH2_RS00075	COG0840	transmembrane signaling receptor activity
PSNIH2_RS00110	COG2199	diguanylate cyclase activity
PSNIH2_RS00120	COG0789	Transcriptional regulator
PSNIH2_RS00130	COG2252	PERMEase
PSNIH2_RS00135	COG0025	NhaP-type Na H and K H
PSNIH2_RS00140	COG0583	DNA-binding transcription factor activity
PSNIH2_RS00145	COG1380	Effector of murein hydrolase LrgA
PSNIH2_RS00155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PSNIH2_RS00160	COG3162	membrane
PSNIH2_RS00170	COG1301	dicarboxylic acid transport
PSNIH2_RS00175	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PSNIH2_RS00180	COG0840	transmembrane signaling receptor activity
PSNIH2_RS00200	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
PSNIH2_RS00225	COG0823	Involved in the tonB-independent uptake of proteins
PSNIH2_RS00260	COG2207	Transcriptional regulator
PSNIH2_RS00265	COG3729	General stress protein
PSNIH2_RS00270	COG3685	Protein conserved in bacteria
PSNIH2_RS00275	COG3546	catalase activity
PSNIH2_RS00280	COG0583	DNA-binding transcription factor activity
PSNIH2_RS00285	COG2814	Major facilitator Superfamily
PSNIH2_RS00290	COG4993	Dehydrogenase
PSNIH2_RS00295	COG2207	Transcriptional regulator
PSNIH2_RS00295	COG3708	Transcriptional regulator
PSNIH2_RS00330	COG1403	HNH endonuclease
PSNIH2_RS00345	COG1309	transcriptional regulator
PSNIH2_RS00350	COG4232	protein-disulfide reductase activity
PSNIH2_RS00360	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PSNIH2_RS00365	COG1027	Aspartate ammonia-lyase
PSNIH2_RS00370	COG3030	protein affecting phage T7 exclusion by the F plasmid
PSNIH2_RS00375	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PSNIH2_RS00390	COG3188	usher protein
PSNIH2_RS00400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSNIH2_RS00400	COG2205	protein histidine kinase activity
PSNIH2_RS00405	COG2197	response regulator
PSNIH2_RS00410	COG1509	lysine 2,3-aminomutase activity
PSNIH2_RS00420	COG5510	response to toxic substance
PSNIH2_RS00445	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PSNIH2_RS00450	COG1053	succinate dehydrogenase
PSNIH2_RS00455	COG0840	transmembrane signaling receptor activity
PSNIH2_RS00460	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
PSNIH2_RS00465	COG3264	Mechanosensitive ion channel
PSNIH2_RS00465	COG1511	domain protein
PSNIH2_RS00470	COG0688	phosphatidylethanolamine metabolic process
PSNIH2_RS00475	COG1162	GTPase activity
PSNIH2_RS00480	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PSNIH2_RS00510	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PSNIH2_RS00510	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PSNIH2_RS00515	COG0802	atpase or kinase
PSNIH2_RS00525	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PSNIH2_RS00530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PSNIH2_RS00535	COG1923	regulation of RNA biosynthetic process
PSNIH2_RS00540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PSNIH2_RS00545	COG0330	HflC and HflK could
PSNIH2_RS00550	COG0330	HflC and HflK could
PSNIH2_RS00560	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
PSNIH2_RS00565	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PSNIH2_RS00575	COG0557	exoribonuclease II activity
PSNIH2_RS00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PSNIH2_RS00585	COG1960	acyl-CoA dehydrogenase activity
PSNIH2_RS00600	COG1073	alpha beta
PSNIH2_RS00610	COG2965	DNA replication, synthesis of RNA primer
PSNIH2_RS00615	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PSNIH2_RS00630	COG3061	Opacity-associated protein A
PSNIH2_RS00640	COG0545	Peptidyl-prolyl cis-trans isomerase
PSNIH2_RS00650	COG1218	3'(2'),5'-bisphosphate nucleotidase
PSNIH2_RS00655	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
PSNIH2_RS00665	COG1253	flavin adenine dinucleotide binding
PSNIH2_RS00670	COG0729	surface antigen
PSNIH2_RS00675	COG2911	Protein conserved in bacteria
PSNIH2_RS00680	COG2105	PFAM AIG2 family protein
PSNIH2_RS00690	COG2707	UPF0756 membrane protein
PSNIH2_RS00695	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PSNIH2_RS00700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PSNIH2_RS00705	COG3028	Belongs to the UPF0307 family
PSNIH2_RS00710	COG0312	modulator of DNA gyrase
PSNIH2_RS00740	COG3964	amidohydrolase
PSNIH2_RS00755	COG2706	6-phosphogluconolactonase activity
PSNIH2_RS00760	COG3711	transcriptional antiterminator
PSNIH2_RS00760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PSNIH2_RS00765	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PSNIH2_RS00770	COG3107	peptidoglycan biosynthetic process
PSNIH2_RS00775	COG0792	nuclease activity
PSNIH2_RS00780	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PSNIH2_RS00785	COG2823	Periplasmic or secreted lipoprotein
PSNIH2_RS00790	COG1741	Belongs to the pirin family
PSNIH2_RS00795	COG0583	DNA-binding transcription factor activity
PSNIH2_RS00800	COG0435	Glutathione S-transferase
PSNIH2_RS00805	COG2259	Doxx family
PSNIH2_RS00815	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
PSNIH2_RS00820	COG4575	ribosome binding
PSNIH2_RS00825	COG1422	Protein of unknown function (DUF1090)
PSNIH2_RS00830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PSNIH2_RS00835	COG0586	Pfam SNARE associated Golgi protein
PSNIH2_RS00845	COG2271	Major facilitator Superfamily
PSNIH2_RS00855	COG0246	Mannitol dehydrogenase
PSNIH2_RS00860	COG2721	sulfolactate sulfo-lyase activity
PSNIH2_RS00865	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PSNIH2_RS00875	COG0673	inositol 2-dehydrogenase activity
PSNIH2_RS00880	COG0038	chloride channel
PSNIH2_RS00885	COG1451	nucleotide metabolic process
PSNIH2_RS00890	COG2813	Specifically methylates the guanine in position
PSNIH2_RS00895	COG0446	pyridine nucleotide-disulphide oxidoreductase
PSNIH2_RS00895	COG1902	pentaerythritol trinitrate reductase activity
PSNIH2_RS00905	COG2197	response regulator
PSNIH2_RS00910	COG1496	oxidoreductase activity
PSNIH2_RS00915	COG0288	reversible hydration of carbon dioxide
PSNIH2_RS00920	COG0659	secondary active sulfate transmembrane transporter activity
PSNIH2_RS00925	COG2199	diguanylate cyclase activity
PSNIH2_RS00950	COG4974	Belongs to the 'phage' integrase family
PSNIH2_RS00995	COG4695	Portal protein
PSNIH2_RS01090	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PSNIH2_RS01145	COG0358	DNA primase activity
PSNIH2_RS01150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PSNIH2_RS01155	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PSNIH2_RS01165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PSNIH2_RS01170	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PSNIH2_RS01175	COG1968	undecaprenyl-diphosphatase activity
PSNIH2_RS01185	COG4991	sh3 domain protein
PSNIH2_RS01190	COG3025	triphosphatase activity
PSNIH2_RS01195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PSNIH2_RS01210	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PSNIH2_RS01225	COG3384	dioxygenase
PSNIH2_RS01230	COG0754	glutathionylspermidine amidase activity
PSNIH2_RS01245	COG0494	nUDIX hydrolase
PSNIH2_RS01250	COG3151	Protein conserved in bacteria
PSNIH2_RS01255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PSNIH2_RS01260	COG3150	esterase
PSNIH2_RS01265	COG0187	DNA topoisomerase II activity
PSNIH2_RS01270	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PSNIH2_RS01275	COG2249	NAD(P)H dehydrogenase (quinone) activity
PSNIH2_RS01285	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PSNIH2_RS01295	COG2132	Multicopper oxidase
PSNIH2_RS01300	COG0656	L-ascorbic acid biosynthetic process
PSNIH2_RS01305	COG2207	Transcriptional regulator
PSNIH2_RS01315	COG0626	cystathionine gamma-synthase activity
PSNIH2_RS01330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PSNIH2_RS01340	COG0848	biopolymer transport protein
PSNIH2_RS01345	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS01355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSNIH2_RS01365	COG4297	protein containing double-stranded beta helix domain
PSNIH2_RS01370	COG2197	response regulator
PSNIH2_RS01410	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PSNIH2_RS01425	COG5001	Diguanylate cyclase
PSNIH2_RS01430	COG1528	Iron-storage protein
PSNIH2_RS01465	COG2003	Belongs to the UPF0758 family
PSNIH2_RS01475	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PSNIH2_RS01500	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PSNIH2_RS01530	COG0625	glutathione transferase activity
PSNIH2_RS01535	COG1473	amidohydrolase
PSNIH2_RS01545	COG2814	Major facilitator Superfamily
PSNIH2_RS01550	COG1902	pentaerythritol trinitrate reductase activity
PSNIH2_RS01555	COG1695	Transcriptional regulator
PSNIH2_RS01560	COG2375	cellular response to nickel ion
PSNIH2_RS01575	COG1902	pentaerythritol trinitrate reductase activity
PSNIH2_RS01580	COG1982	Orn Lys Arg decarboxylase major
PSNIH2_RS01590	COG3916	Acyl-homoserine-lactone synthase
PSNIH2_RS01600	COG5441	Belongs to the UPF0261 family
PSNIH2_RS01605	COG5564	TIM-barrel signal transduction protein
PSNIH2_RS01610	COG2831	hemolysin activation secretion protein
PSNIH2_RS01620	COG0741	lytic transglycosylase activity
PSNIH2_RS01630	COG1194	a g-specific adenine glycosylase
PSNIH2_RS01640	COG3171	Protein conserved in bacteria
PSNIH2_RS01660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PSNIH2_RS01665	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PSNIH2_RS01670	COG0762	integral membrane protein
PSNIH2_RS01675	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PSNIH2_RS01680	COG2805	Type II/IV secretion system protein
PSNIH2_RS01685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PSNIH2_RS01690	COG1678	Uncharacterized ACR, COG1678
PSNIH2_RS01700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PSNIH2_RS01705	COG2356	endonuclease I
PSNIH2_RS01710	COG3091	SprT-like family
PSNIH2_RS01715	COG2814	Major facilitator Superfamily
PSNIH2_RS01720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PSNIH2_RS01730	COG1166	arginine decarboxylase activity
PSNIH2_RS01740	COG2146	nitrite reductase [NAD(P)H] activity
PSNIH2_RS01755	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS01760	COG1414	Transcriptional regulator
PSNIH2_RS01790	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS01795	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
PSNIH2_RS01805	COG0028	Belongs to the TPP enzyme family
PSNIH2_RS01810	COG0501	Belongs to the peptidase M48B family
PSNIH2_RS01815	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PSNIH2_RS01825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PSNIH2_RS01830	COG0126	phosphoglycerate kinase activity
PSNIH2_RS01835	COG0191	fructose-bisphosphate aldolase activity
PSNIH2_RS01840	COG0668	transmembrane transport
PSNIH2_RS01850	COG2968	Membrane
PSNIH2_RS01855	COG0583	DNA-binding transcription factor activity
PSNIH2_RS01860	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PSNIH2_RS01865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PSNIH2_RS01870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PSNIH2_RS01875	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PSNIH2_RS01880	COG3079	Belongs to the UPF0149 family
PSNIH2_RS01885	COG0006	proline dipeptidase activity
PSNIH2_RS01890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSNIH2_RS01895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSNIH2_RS01905	COG0509	glycine decarboxylation via glycine cleavage system
PSNIH2_RS01920	COG2723	6-phospho-beta-galactosidase activity
PSNIH2_RS01930	COG1272	protein, Hemolysin III
PSNIH2_RS01935	COG0354	folic acid binding
PSNIH2_RS01955	COG4974	Belongs to the 'phage' integrase family
PSNIH2_RS01960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PSNIH2_RS01965	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PSNIH2_RS01980	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PSNIH2_RS01990	COG2814	Major facilitator Superfamily
PSNIH2_RS02000	COG0583	DNA-binding transcription factor activity
PSNIH2_RS02010	COG1447	Phosphotransferase system cellobiose-specific component IIA
PSNIH2_RS02015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PSNIH2_RS02020	COG2723	6-phospho-beta-galactosidase activity
PSNIH2_RS02025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PSNIH2_RS02030	COG2186	Transcriptional regulator
PSNIH2_RS02045	COG1609	Transcriptional regulator
PSNIH2_RS02055	COG0768	penicillin binding
PSNIH2_RS02065	COG0318	PFAM AMP-dependent synthetase and ligase
PSNIH2_RS02065	COG0204	Acyl-transferase
PSNIH2_RS02080	COG0667	Aldo Keto reductase
PSNIH2_RS02090	COG0861	Integral membrane protein TerC family
PSNIH2_RS02095	COG3066	DNA modification
PSNIH2_RS02105	COG1051	belongs to the nudix hydrolase family
PSNIH2_RS02115	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PSNIH2_RS02120	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PSNIH2_RS02125	COG4608	Belongs to the ABC transporter superfamily
PSNIH2_RS02130	COG0444	Belongs to the ABC transporter superfamily
PSNIH2_RS02135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSNIH2_RS02140	COG0601	transmembrane transport
PSNIH2_RS02145	COG0747	negative chemotaxis
PSNIH2_RS02150	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PSNIH2_RS02165	COG4795	General secretion pathway protein
PSNIH2_RS02180	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PSNIH2_RS02185	COG1025	Belongs to the peptidase M16 family
PSNIH2_RS02190	COG1074	ATP-dependent DNA helicase activity
PSNIH2_RS02195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PSNIH2_RS02200	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PSNIH2_RS02200	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PSNIH2_RS02205	COG0860	N-Acetylmuramoyl-L-alanine amidase
PSNIH2_RS02220	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PSNIH2_RS02225	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PSNIH2_RS02230	COG2166	iron-sulfur cluster assembly
PSNIH2_RS02235	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PSNIH2_RS02245	COG0583	DNA-binding transcription factor activity
PSNIH2_RS02250	COG2363	Small membrane protein
PSNIH2_RS02255	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PSNIH2_RS02275	COG1611	Belongs to the LOG family
PSNIH2_RS02280	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PSNIH2_RS02280	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PSNIH2_RS02290	COG3098	single-species biofilm formation
PSNIH2_RS02295	COG0564	pseudouridine synthase activity
PSNIH2_RS02300	COG0716	FMN binding
PSNIH2_RS02305	COG2721	sulfolactate sulfo-lyase activity
PSNIH2_RS02315	COG2271	Major facilitator Superfamily
PSNIH2_RS02320	COG4948	Mandelate Racemase Muconate Lactonizing
PSNIH2_RS02325	COG4948	Mandelate Racemase Muconate Lactonizing
PSNIH2_RS02335	COG2084	Dehydrogenase
PSNIH2_RS02340	COG1929	Belongs to the glycerate kinase type-1 family
PSNIH2_RS02350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PSNIH2_RS02355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PSNIH2_RS02360	COG3956	TIGRFAM MazG family protein
PSNIH2_RS02365	COG0504	CTP synthase activity
PSNIH2_RS02375	COG0602	queuosine metabolic process
PSNIH2_RS02380	COG0723	plastoquinol--plastocyanin reductase activity
PSNIH2_RS02380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSNIH2_RS02385	COG0720	synthase
PSNIH2_RS02395	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSNIH2_RS02400	COG0175	sulfate reduction
PSNIH2_RS02410	COG2234	aminopeptidase activity
PSNIH2_RS02415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PSNIH2_RS02415	COG1648	precorrin-2 dehydrogenase activity
PSNIH2_RS02425	COG2895	sulfate adenylyltransferase (ATP) activity
PSNIH2_RS02440	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PSNIH2_RS02445	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PSNIH2_RS02455	COG0585	pseudouridine synthase activity
PSNIH2_RS02465	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PSNIH2_RS02470	COG1388	LysM domain
PSNIH2_RS02470	COG4942	peptidase
PSNIH2_RS02475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PSNIH2_RS02480	COG2963	transposase activity
PSNIH2_RS02485	COG2801	Transposase and inactivated derivatives
PSNIH2_RS02495	COG2814	Major facilitator Superfamily
PSNIH2_RS02515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PSNIH2_RS02520	COG2824	Alkylphosphonate utilization operon protein PhnA
PSNIH2_RS02525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSNIH2_RS02530	COG1546	Belongs to the CinA family
PSNIH2_RS02550	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PSNIH2_RS02575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PSNIH2_RS02580	COG1238	metal cluster binding
PSNIH2_RS02585	COG2918	glutathione biosynthetic process
PSNIH2_RS02595	COG4536	flavin adenine dinucleotide binding
PSNIH2_RS02600	COG4137	Cytochrome C assembly protein
PSNIH2_RS02605	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PSNIH2_RS02610	COG0228	four-way junction DNA binding
PSNIH2_RS02635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PSNIH2_RS02640	COG1605	Chorismate mutase
PSNIH2_RS02640	COG0287	Prephenate dehydrogenase
PSNIH2_RS02645	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS02650	COG1605	Chorismate mutase
PSNIH2_RS02650	COG0077	Prephenate dehydratase
PSNIH2_RS02655	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PSNIH2_RS02660	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PSNIH2_RS02665	COG0564	pseudouridine synthase activity
PSNIH2_RS02670	COG1496	oxidoreductase activity
PSNIH2_RS02675	COG0542	response to heat
PSNIH2_RS02705	COG0477	Major facilitator Superfamily
PSNIH2_RS02710	COG5544	Lipoprotein
PSNIH2_RS02715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PSNIH2_RS02720	COG0045	succinate-CoA ligase (ADP-forming) activity
PSNIH2_RS02720	COG1042	CoA-binding domain protein
PSNIH2_RS02720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PSNIH2_RS02725	COG3148	PFAM DTW domain containing protein
PSNIH2_RS02730	COG3118	belongs to the thioredoxin family
PSNIH2_RS02735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PSNIH2_RS02740	COG2814	Major facilitator Superfamily
PSNIH2_RS02745	COG1566	PFAM secretion protein HlyD family protein
PSNIH2_RS02750	COG1846	Transcriptional regulator
PSNIH2_RS02755	COG2814	Major facilitator Superfamily
PSNIH2_RS02775	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PSNIH2_RS02785	COG1780	Probably involved in ribonucleotide reductase function
PSNIH2_RS02795	COG4575	ribosome binding
PSNIH2_RS02805	COG0833	amino acid
PSNIH2_RS02810	COG2040	homocysteine
PSNIH2_RS02820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PSNIH2_RS02830	COG1764	response to oxidative stress
PSNIH2_RS02835	COG3275	phosphorelay sensor kinase activity
PSNIH2_RS02845	COG4807	Protein conserved in bacteria
PSNIH2_RS02850	COG4773	Receptor
PSNIH2_RS02860	COG1349	DNA-binding transcription factor activity
PSNIH2_RS02865	COG0494	nUDIX hydrolase
PSNIH2_RS02880	COG4566	intracellular signal transduction
PSNIH2_RS02885	COG1966	Carbon starvation protein
PSNIH2_RS02900	COG2076	Multidrug Resistance protein
PSNIH2_RS02935	COG0582	viral genome integration into host DNA
PSNIH2_RS02945	COG2867	negative regulation of translational initiation
PSNIH2_RS02960	COG0497	DNA recombination
PSNIH2_RS02965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PSNIH2_RS02970	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PSNIH2_RS02975	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PSNIH2_RS02980	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
PSNIH2_RS02985	COG0513	Belongs to the DEAD box helicase family
PSNIH2_RS02995	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PSNIH2_RS03010	COG3026	antisigma factor binding
PSNIH2_RS03015	COG3086	response to oxidative stress
PSNIH2_RS03020	COG0481	GTPase activity
PSNIH2_RS03030	COG0571	ribonuclease III activity
PSNIH2_RS03040	COG1381	Involved in DNA repair and RecF pathway recombination
PSNIH2_RS03045	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PSNIH2_RS03050	COG0736	holo-[acyl-carrier-protein] synthase activity
PSNIH2_RS03055	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PSNIH2_RS03060	COG1737	Transcriptional regulator
PSNIH2_RS03065	COG0560	Phosphoserine phosphatase
PSNIH2_RS03075	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PSNIH2_RS03080	COG0047	phosphoribosylformylglycinamidine synthase activity
PSNIH2_RS03080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PSNIH2_RS03085	COG2205	protein histidine kinase activity
PSNIH2_RS03090	COG3170	Tfp pilus assembly protein FimV
PSNIH2_RS03095	COG2204	response regulator
PSNIH2_RS03100	COG0347	Belongs to the P(II) protein family
PSNIH2_RS03105	COG1794	racemase activity, acting on amino acids and derivatives
PSNIH2_RS03115	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PSNIH2_RS03120	COG2814	Major facilitator Superfamily
PSNIH2_RS03125	COG3711	transcriptional antiterminator
PSNIH2_RS03130	COG3683	transport system, periplasmic component
PSNIH2_RS03135	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
PSNIH2_RS03140	COG0483	inositol monophosphate 1-phosphatase activity
PSNIH2_RS03150	COG1959	2 iron, 2 sulfur cluster binding
PSNIH2_RS03160	COG0822	iron-sulfur transferase activity
PSNIH2_RS03170	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PSNIH2_RS03180	COG0633	Ferredoxin
PSNIH2_RS03185	COG2975	iron-sulfur cluster assembly
PSNIH2_RS03190	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PSNIH2_RS03200	COG2897	thiosulfate sulfurtransferase activity
PSNIH2_RS03205	COG2373	Large extracellular alpha-helical protein
PSNIH2_RS03210	COG4953	penicillin-binding protein 1C
PSNIH2_RS03215	COG0105	UTP biosynthetic process
PSNIH2_RS03220	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PSNIH2_RS03230	COG1426	Protein conserved in bacteria
PSNIH2_RS03240	COG0124	histidyl-tRNA synthetase
PSNIH2_RS03245	COG2976	Protein conserved in bacteria
PSNIH2_RS03250	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PSNIH2_RS03255	COG1160	GTP binding
PSNIH2_RS03260	COG1645	bacterial-type flagellum-dependent swarming motility
PSNIH2_RS03265	COG4993	Dehydrogenase
PSNIH2_RS03285	COG2271	Major facilitator Superfamily
PSNIH2_RS03295	COG1570	exodeoxyribonuclease VII activity
PSNIH2_RS03300	COG0516	GMP reductase activity
PSNIH2_RS03300	COG0517	IMP dehydrogenase activity
PSNIH2_RS03320	COG2239	Acts as a magnesium transporter
PSNIH2_RS03330	COG2200	EAL domain
PSNIH2_RS03335	COG0500	methyltransferase
PSNIH2_RS03340	COG0248	Ppx GppA phosphatase
PSNIH2_RS03345	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PSNIH2_RS03350	COG0573	inorganic phosphate transmembrane transporter activity
PSNIH2_RS03355	COG0581	inorganic phosphate transmembrane transporter activity
PSNIH2_RS03360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PSNIH2_RS03365	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PSNIH2_RS03370	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PSNIH2_RS03380	COG2233	PERMEase
PSNIH2_RS03405	COG1393	Belongs to the ArsC family
PSNIH2_RS03410	COG4783	chaperone-mediated protein folding
PSNIH2_RS03430	COG0628	permease
PSNIH2_RS03435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PSNIH2_RS03440	COG2716	regulation of RNA biosynthetic process
PSNIH2_RS03445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSNIH2_RS03450	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PSNIH2_RS03460	COG2321	neutral zinc metallopeptidase
PSNIH2_RS03465	COG1444	tRNA N-acetyltransferase activity
PSNIH2_RS03470	COG0400	carboxylic ester hydrolase activity
PSNIH2_RS03480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PSNIH2_RS03485	COG1393	Belongs to the ArsC family
PSNIH2_RS03495	COG2197	response regulator
PSNIH2_RS03500	COG3850	Histidine kinase
PSNIH2_RS03510	COG2197	response regulator
PSNIH2_RS03515	COG2223	nitrite transmembrane transporter activity
PSNIH2_RS03520	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PSNIH2_RS03525	COG1140	nitrate reductase beta subunit
PSNIH2_RS03530	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PSNIH2_RS03535	COG2181	nitrate reductase activity
PSNIH2_RS03545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PSNIH2_RS03555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PSNIH2_RS03560	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSNIH2_RS03565	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSNIH2_RS03570	COG1129	ABC transporter
PSNIH2_RS03580	COG1349	DNA-binding transcription factor activity
PSNIH2_RS03585	COG5342	invasion associated locus B
PSNIH2_RS03590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PSNIH2_RS03620	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PSNIH2_RS03625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PSNIH2_RS03635	COG0408	coproporphyrinogen oxidase activity
PSNIH2_RS03640	COG0860	N-Acetylmuramoyl-L-alanine amidase
PSNIH2_RS03645	COG0456	acetyltransferase
PSNIH2_RS03660	COG2837	iron assimilation
PSNIH2_RS03670	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PSNIH2_RS03675	COG4208	sulfate ABC transporter
PSNIH2_RS03680	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PSNIH2_RS03690	COG1136	(ABC) transporter
PSNIH2_RS03690	COG0577	efflux transmembrane transporter activity
PSNIH2_RS03695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSNIH2_RS03700	COG0745	RESPONSE REGULATOR receiver
PSNIH2_RS03705	COG2205	protein histidine kinase activity
PSNIH2_RS03715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PSNIH2_RS03735	COG3115	cell septum assembly
PSNIH2_RS03745	COG3530	Putative quorum-sensing-regulated virulence factor
PSNIH2_RS03750	COG0385	Bile acid
PSNIH2_RS03755	COG0583	DNA-binding transcription factor activity
PSNIH2_RS03785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PSNIH2_RS03790	COG3415	Transposase
PSNIH2_RS03795	COG2116	formate transmembrane transporter activity
PSNIH2_RS03810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PSNIH2_RS03815	COG1914	H( )-stimulated, divalent metal cation uptake system
PSNIH2_RS03825	COG0667	Aldo Keto reductase
PSNIH2_RS03830	COG3961	Belongs to the TPP enzyme family
PSNIH2_RS03835	COG0837	glucose binding
PSNIH2_RS03840	COG3279	Response regulator of the LytR AlgR family
PSNIH2_RS03845	COG3275	phosphorelay sensor kinase activity
PSNIH2_RS03850	COG0436	Aminotransferase
PSNIH2_RS03895	COG2723	6-phospho-beta-galactosidase activity
PSNIH2_RS03905	COG2223	nitrite transmembrane transporter activity
PSNIH2_RS03935	COG2246	polysaccharide biosynthetic process
PSNIH2_RS03940	COG0582	viral genome integration into host DNA
PSNIH2_RS03950	COG2116	formate transmembrane transporter activity
PSNIH2_RS03960	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PSNIH2_RS03965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PSNIH2_RS03970	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PSNIH2_RS03975	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PSNIH2_RS03980	COG1138	Cytochrome C-type biogenesis protein
PSNIH2_RS03990	COG3088	subunit of a heme lyase
PSNIH2_RS03990	COG4235	cytochrome complex assembly
PSNIH2_RS03995	COG4235	cytochrome complex assembly
PSNIH2_RS03995	COG3088	subunit of a heme lyase
PSNIH2_RS04005	COG2067	long-chain fatty acid transport protein
PSNIH2_RS04010	COG3691	Protein conserved in bacteria
PSNIH2_RS04020	COG1250	3-hydroxyacyl-CoA dehydrogenase
PSNIH2_RS04020	COG1024	Enoyl-CoA hydratase
PSNIH2_RS04025	COG2062	phosphohistidine phosphatase, SixA
PSNIH2_RS04030	COG2840	Smr protein MutS2
PSNIH2_RS04040	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PSNIH2_RS04050	COG0730	response to heat
PSNIH2_RS04055	COG3101	peptidyl-lysine hydroxylation
PSNIH2_RS04070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PSNIH2_RS04110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PSNIH2_RS04120	COG0586	Pfam SNARE associated Golgi protein
PSNIH2_RS04130	COG0285	dihydrofolate synthase activity
PSNIH2_RS04135	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
PSNIH2_RS04140	COG1286	toxin biosynthetic process
PSNIH2_RS04145	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PSNIH2_RS04160	COG0667	Aldo Keto reductase
PSNIH2_RS04165	COG0583	DNA-binding transcription factor activity
PSNIH2_RS04170	COG0163	prenyltransferase activity
PSNIH2_RS04175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSNIH2_RS04180	COG4215	(ABC) transporter
PSNIH2_RS04185	COG4160	amino acid transport
PSNIH2_RS04190	COG4598	ABC transporter
PSNIH2_RS04195	COG1090	epimerase
PSNIH2_RS04200	COG0625	glutathione transferase activity
PSNIH2_RS04210	COG1609	Transcriptional regulator
PSNIH2_RS04215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PSNIH2_RS04230	COG3959	Transketolase, thiamine diphosphate binding domain
PSNIH2_RS04235	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PSNIH2_RS04245	COG0280	phosphate acetyltransferase
PSNIH2_RS04245	COG0857	belongs to the CobB CobQ family
PSNIH2_RS04250	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PSNIH2_RS04255	COG3092	negative regulation of chromosome organization
PSNIH2_RS04260	COG3013	Belongs to the UPF0304 family
PSNIH2_RS04265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PSNIH2_RS04270	COG0490	domain, Protein
PSNIH2_RS04270	COG0471	metal ion transport
PSNIH2_RS04275	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
PSNIH2_RS04280	COG0436	Aminotransferase
PSNIH2_RS04285	COG0583	DNA-binding transcription factor activity
PSNIH2_RS04290	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSNIH2_RS04300	COG0649	NAD binding
PSNIH2_RS04300	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSNIH2_RS04330	COG0839	Belongs to the complex I subunit 6 family
PSNIH2_RS04335	COG0713	ATP synthesis coupled electron transport
PSNIH2_RS04340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PSNIH2_RS04345	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSNIH2_RS04350	COG1007	ATP synthesis coupled electron transport
PSNIH2_RS04355	COG2153	protein acetylation
PSNIH2_RS04360	COG0431	NADPH-dependent FMN reductase
PSNIH2_RS04370	COG4575	ribosome binding
PSNIH2_RS04375	COG1169	isochorismate synthase
PSNIH2_RS04390	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PSNIH2_RS04395	COG1441	menaquinone biosynthetic process
PSNIH2_RS04415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PSNIH2_RS04420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PSNIH2_RS04425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PSNIH2_RS04440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PSNIH2_RS04455	COG0784	Response regulator, receiver
PSNIH2_RS04455	COG2205	protein histidine kinase activity
PSNIH2_RS04460	COG2197	response regulator
PSNIH2_RS04465	COG0642	Histidine kinase
PSNIH2_RS04465	COG2198	Histidine kinase
PSNIH2_RS04470	COG2223	nitrite transmembrane transporter activity
PSNIH2_RS04485	COG1132	(ABC) transporter
PSNIH2_RS04495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PSNIH2_RS04510	COG4615	Cyclic peptide transporter
PSNIH2_RS04520	COG0840	transmembrane signaling receptor activity
PSNIH2_RS04540	COG0697	spore germination
PSNIH2_RS04545	COG0789	Transcriptional regulator
PSNIH2_RS04570	COG3082	Protein of unknown function (DUF1414)
PSNIH2_RS04580	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PSNIH2_RS04585	COG1061	Type III restriction enzyme res subunit
PSNIH2_RS04590	COG1187	pseudouridine synthase activity
PSNIH2_RS04595	COG2814	Major facilitator Superfamily
PSNIH2_RS04605	COG4172	Belongs to the ABC transporter superfamily
PSNIH2_RS04610	COG4239	(ABC) transporter, permease
PSNIH2_RS04615	COG4174	ABC transporter (Permease)
PSNIH2_RS04620	COG4166	transmembrane transport
PSNIH2_RS04625	COG2200	EAL domain
PSNIH2_RS04630	COG0791	NLP P60 protein
PSNIH2_RS04635	COG0671	phosphoesterase, PA-phosphatase related
PSNIH2_RS04640	COG0523	cobalamin synthesis protein
PSNIH2_RS04650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PSNIH2_RS04660	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PSNIH2_RS04660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PSNIH2_RS04665	COG1105	Belongs to the carbohydrate kinase PfkB family
PSNIH2_RS04670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PSNIH2_RS04670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PSNIH2_RS04670	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PSNIH2_RS04680	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PSNIH2_RS04685	COG2855	membrane
PSNIH2_RS04695	COG0583	DNA-binding transcription factor activity
PSNIH2_RS04700	COG0833	amino acid
PSNIH2_RS04705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PSNIH2_RS04710	COG1120	ATPase activity
PSNIH2_RS04715	COG4771	TonB-dependent receptor
PSNIH2_RS04730	COG0583	DNA-binding transcription factor activity
PSNIH2_RS04735	COG0477	Major facilitator Superfamily
PSNIH2_RS04745	COG2311	Membrane
PSNIH2_RS04750	COG1609	Transcriptional regulator
PSNIH2_RS04760	COG1129	ABC transporter
PSNIH2_RS04770	COG2949	membrane
PSNIH2_RS04775	COG0281	malic enzyme
PSNIH2_RS04780	COG0295	cytidine deaminase activity
PSNIH2_RS04785	COG1346	cytolysis
PSNIH2_RS04795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PSNIH2_RS04795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PSNIH2_RS04805	COG1454	alcohol dehydrogenase
PSNIH2_RS04815	COG0243	molybdopterin cofactor binding
PSNIH2_RS04820	COG3005	denitrification pathway
PSNIH2_RS04825	COG2814	Major facilitator Superfamily
PSNIH2_RS04830	COG4574	serine-type endopeptidase inhibitor activity
PSNIH2_RS04840	COG2951	lytic endotransglycosylase activity
PSNIH2_RS04845	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS04855	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSNIH2_RS04860	COG1129	ABC transporter
PSNIH2_RS04870	COG1879	ABC-type sugar transport system periplasmic component
PSNIH2_RS04880	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PSNIH2_RS04890	COG3959	Transketolase, thiamine diphosphate binding domain
PSNIH2_RS04895	COG3958	Transketolase
PSNIH2_RS04945	COG1830	Aldolase
PSNIH2_RS04950	COG1802	Transcriptional regulator
PSNIH2_RS04955	COG0246	Mannitol dehydrogenase
PSNIH2_RS04960	COG2271	Major facilitator Superfamily
PSNIH2_RS04965	COG1063	alcohol dehydrogenase
PSNIH2_RS04970	COG4948	Mandelate Racemase Muconate Lactonizing
PSNIH2_RS04975	COG1597	lipid kinase activity
PSNIH2_RS04980	COG0826	peptidase U32
PSNIH2_RS04985	COG0745	RESPONSE REGULATOR receiver
PSNIH2_RS04990	COG2205	protein histidine kinase activity
PSNIH2_RS05010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSNIH2_RS05015	COG0667	Aldo Keto reductase
PSNIH2_RS05025	COG0443	Heat shock 70 kDa protein
PSNIH2_RS05030	COG5001	Diguanylate cyclase
PSNIH2_RS05030	COG5002	protein histidine kinase activity
PSNIH2_RS05030	COG3447	MASE1 domain protein
PSNIH2_RS05040	COG0572	uridine kinase
PSNIH2_RS05045	COG0717	Belongs to the dCTP deaminase family
PSNIH2_RS05050	COG2982	Protein involved in outer membrane biogenesis
PSNIH2_RS05055	COG1253	flavin adenine dinucleotide binding
PSNIH2_RS05065	COG1596	polysaccharide export
PSNIH2_RS05070	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PSNIH2_RS05075	COG0489	protein tyrosine kinase activity
PSNIH2_RS05075	COG3206	protein involved in exopolysaccharide biosynthesis
PSNIH2_RS05105	COG1442	glycosyl transferase family 8
PSNIH2_RS05105	COG1216	Glycosyl transferase, family 2
PSNIH2_RS05110	COG2327	Polysaccharide pyruvyl transferase
PSNIH2_RS05115	COG2244	polysaccharide biosynthetic process
PSNIH2_RS05135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PSNIH2_RS05140	COG3562	capsule polysaccharide
PSNIH2_RS05160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSNIH2_RS05180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PSNIH2_RS05190	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PSNIH2_RS05190	COG0140	phosphoribosyl-ATP diphosphatase activity
PSNIH2_RS05200	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PSNIH2_RS05215	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PSNIH2_RS05225	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PSNIH2_RS05230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSNIH2_RS05235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSNIH2_RS05240	COG1917	Cupin 2, conserved barrel domain protein
PSNIH2_RS05240	COG1396	sequence-specific DNA binding
PSNIH2_RS05245	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PSNIH2_RS05250	COG0174	glutamine synthetase
PSNIH2_RS05255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PSNIH2_RS05260	COG0531	amino acid
PSNIH2_RS05270	COG2925	Exonuclease
PSNIH2_RS05300	COG0243	molybdopterin cofactor binding
PSNIH2_RS05325	COG1289	transmembrane transporter activity
PSNIH2_RS05360	COG0647	UMP catabolic process
PSNIH2_RS05375	COG1129	ABC transporter
PSNIH2_RS05380	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSNIH2_RS05385	COG2851	Citrate transporter
PSNIH2_RS05405	COG0028	Belongs to the TPP enzyme family
PSNIH2_RS05410	COG0300	oxidoreductase activity
PSNIH2_RS05415	COG3300	MHYT domain
PSNIH2_RS05415	COG5001	Diguanylate cyclase
PSNIH2_RS05420	COG2188	Transcriptional regulator
PSNIH2_RS05425	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
PSNIH2_RS05435	COG2252	PERMEase
PSNIH2_RS05440	COG2076	Multidrug Resistance protein
PSNIH2_RS05445	COG2076	Multidrug Resistance protein
PSNIH2_RS05450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PSNIH2_RS05455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PSNIH2_RS05460	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PSNIH2_RS05465	COG2080	2 iron, 2 sulfur cluster binding
PSNIH2_RS05485	COG1120	ATPase activity
PSNIH2_RS05490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PSNIH2_RS05500	COG3119	arylsulfatase activity
PSNIH2_RS05505	COG0641	radical SAM
PSNIH2_RS05515	COG0534	Mate efflux family protein
PSNIH2_RS05525	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS05555	COG1418	mRNA catabolic process
PSNIH2_RS05575	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PSNIH2_RS05580	COG3727	T/G mismatch-specific endonuclease activity
PSNIH2_RS05585	COG0697	spore germination
PSNIH2_RS05595	COG2354	Protein conserved in bacteria
PSNIH2_RS05600	COG5475	Uncharacterized small protein (DUF2158)
PSNIH2_RS05615	COG1215	transferase activity, transferring glycosyl groups
PSNIH2_RS05635	COG0840	transmembrane signaling receptor activity
PSNIH2_RS05655	COG1338	Plays a role in the flagellum-specific transport system
PSNIH2_RS05660	COG3190	flagellar
PSNIH2_RS05665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PSNIH2_RS05675	COG1580	Controls the rotational direction of flagella during chemotaxis
PSNIH2_RS05685	COG2882	bacterial-type flagellum organization
PSNIH2_RS05700	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PSNIH2_RS05710	COG1677	Flagellar hook-basal body complex protein FliE
PSNIH2_RS05720	COG0583	DNA-binding transcription factor activity
PSNIH2_RS05725	COG0702	epimerase
PSNIH2_RS05730	COG0667	Aldo Keto reductase
PSNIH2_RS05735	COG2223	nitrite transmembrane transporter activity
PSNIH2_RS05745	COG0251	oxidation-reduction process
PSNIH2_RS05750	COG0840	transmembrane signaling receptor activity
PSNIH2_RS05760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PSNIH2_RS05770	COG2249	NAD(P)H dehydrogenase (quinone) activity
PSNIH2_RS05790	COG0659	secondary active sulfate transmembrane transporter activity
PSNIH2_RS05800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PSNIH2_RS05805	COG1393	Belongs to the ArsC family
PSNIH2_RS05840	COG1113	amino acid transport
PSNIH2_RS05855	COG1278	Cold shock
PSNIH2_RS05910	COG0438	transferase activity, transferring glycosyl groups
PSNIH2_RS05910	COG1216	Glycosyl transferase, family 2
PSNIH2_RS05955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSNIH2_RS05960	COG0765	amino acid transport
PSNIH2_RS05965	COG1126	abc transporter atp-binding protein
PSNIH2_RS05990	COG3157	Type VI secretion system effector, Hcp
PSNIH2_RS06000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PSNIH2_RS06015	COG1280	lysine exporter protein (LysE YggA)
PSNIH2_RS06040	COG1522	sequence-specific DNA binding
PSNIH2_RS06050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSNIH2_RS06055	COG5457	Domain of unknown function (DUF1127)
PSNIH2_RS06065	COG2822	iron ion transport
PSNIH2_RS06075	COG1702	phosphate starvation-inducible protein PhoH
PSNIH2_RS06090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PSNIH2_RS06100	COG2814	Major facilitator Superfamily
PSNIH2_RS06105	COG0583	DNA-binding transcription factor activity
PSNIH2_RS06115	COG2135	peptidase activity
PSNIH2_RS06120	COG1877	trehalose-phosphatase activity
PSNIH2_RS06155	COG0835	chemotaxis
PSNIH2_RS06170	COG0840	transmembrane signaling receptor activity
PSNIH2_RS06175	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PSNIH2_RS06185	COG0745	RESPONSE REGULATOR receiver
PSNIH2_RS06210	COG0018	arginyl-trna synthetase
PSNIH2_RS06215	COG3102	Protein conserved in bacteria
PSNIH2_RS06220	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PSNIH2_RS06225	COG3142	Participates in the control of copper homeostasis
PSNIH2_RS06275	COG1280	lysine exporter protein (LysE YggA)
PSNIH2_RS06280	COG0500	methyltransferase
PSNIH2_RS06290	COG1801	Protein of unknown function DUF72
PSNIH2_RS06320	COG2963	transposase activity
PSNIH2_RS06325	COG2801	Transposase and inactivated derivatives
PSNIH2_RS06355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PSNIH2_RS06360	COG1801	Protein of unknown function DUF72
PSNIH2_RS06365	COG1335	isochorismatase
PSNIH2_RS06375	COG0494	nUDIX hydrolase
PSNIH2_RS06390	COG0632	four-way junction helicase activity
PSNIH2_RS06395	COG2255	four-way junction helicase activity
PSNIH2_RS06400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PSNIH2_RS06410	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PSNIH2_RS06415	COG0739	heme binding
PSNIH2_RS06420	COG1560	Kdo2-lipid A biosynthetic process
PSNIH2_RS06435	COG3486	L-lysine 6-monooxygenase (NADPH) activity
PSNIH2_RS06440	COG0076	glutamate decarboxylase activity
PSNIH2_RS06445	COG0469	pyruvate kinase activity
PSNIH2_RS06450	COG1737	Transcriptional regulator
PSNIH2_RS06455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PSNIH2_RS06460	COG0800	Aldolase
PSNIH2_RS06470	COG3141	response to X-ray
PSNIH2_RS06475	COG2979	Protein of unknown function (DUF533)
PSNIH2_RS06480	COG1770	oligopeptidase
PSNIH2_RS06485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PSNIH2_RS06495	COG2372	response to copper ion
PSNIH2_RS06540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PSNIH2_RS06565	COG1396	sequence-specific DNA binding
PSNIH2_RS06575	COG0582	viral genome integration into host DNA
PSNIH2_RS06635	COG2003	Belongs to the UPF0758 family
PSNIH2_RS06710	COG3621	Patatin-like phospholipase
PSNIH2_RS06890	COG1192	Involved in chromosome partitioning
PSNIH2_RS06905	COG0583	DNA-binding transcription factor activity
PSNIH2_RS06925	COG0071	Belongs to the small heat shock protein (HSP20) family
PSNIH2_RS06930	COG0542	response to heat
PSNIH2_RS06940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PSNIH2_RS06985	COG0501	Belongs to the peptidase M48B family
PSNIH2_RS06990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSNIH2_RS06995	COG0583	DNA-binding transcription factor activity
PSNIH2_RS07000	COG0454	-acetyltransferase
PSNIH2_RS07045	COG3008	intermembrane lipid transfer
PSNIH2_RS07050	COG2995	paraquat-inducible protein a
PSNIH2_RS07055	COG1956	GAF domain-containing protein
PSNIH2_RS07060	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
PSNIH2_RS07070	COG0501	Belongs to the peptidase M48B family
PSNIH2_RS07075	COG2814	Major facilitator Superfamily
PSNIH2_RS07105	COG2226	methyltransferase
PSNIH2_RS07110	COG1971	Probably functions as a manganese efflux pump
PSNIH2_RS07120	COG3716	PTS system mannose fructose sorbose family IID component
PSNIH2_RS07125	COG3715	PTS system
PSNIH2_RS07130	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PSNIH2_RS07130	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
PSNIH2_RS07135	COG1253	flavin adenine dinucleotide binding
PSNIH2_RS07140	COG2200	EAL domain
PSNIH2_RS07145	COG1760	l-serine dehydratase
PSNIH2_RS07160	COG3140	Belongs to the UPF0181 family
PSNIH2_RS07165	COG0251	oxidation-reduction process
PSNIH2_RS07170	COG1199	ATP-dependent helicase activity
PSNIH2_RS07175	COG1214	PFAM Peptidase M22, glycoprotease
PSNIH2_RS07180	COG3065	identical protein binding
PSNIH2_RS07185	COG0318	PFAM AMP-dependent synthetase and ligase
PSNIH2_RS07195	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PSNIH2_RS07200	COG2894	cell division
PSNIH2_RS07205	COG0850	regulation of cytokinetic process
PSNIH2_RS07215	COG2951	lytic endotransglycosylase activity
PSNIH2_RS07220	COG0179	Fumarylacetoacetate (FAA) hydrolase
PSNIH2_RS07235	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PSNIH2_RS07240	COG2186	Transcriptional regulator
PSNIH2_RS07245	COG2719	SpoVR family
PSNIH2_RS07250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSNIH2_RS07255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PSNIH2_RS07280	COG2718	Belongs to the UPF0229 family
PSNIH2_RS07285	COG2766	serine protein kinase
PSNIH2_RS07290	COG3713	MltA-interacting MipA family protein
PSNIH2_RS07295	COG0656	L-ascorbic acid biosynthetic process
PSNIH2_RS07310	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PSNIH2_RS07315	COG3139	Protein of unknown function (DUF1315)
PSNIH2_RS07320	COG1335	isochorismatase
PSNIH2_RS07325	COG0252	asparaginase activity
PSNIH2_RS07330	COG0616	signal peptide processing
PSNIH2_RS07335	COG0778	Nitroreductase
PSNIH2_RS07340	COG0709	Synthesizes selenophosphate from selenide and ATP
PSNIH2_RS07345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PSNIH2_RS07355	COG0708	Exodeoxyribonuclease III
PSNIH2_RS07370	COG0788	formyltetrahydrofolate deformylase activity
PSNIH2_RS07375	COG3012	SEC-C Motif Domain Protein
PSNIH2_RS07380	COG1752	Esterase of the alpha-beta hydrolase superfamily
PSNIH2_RS07385	COG0745	RESPONSE REGULATOR receiver
PSNIH2_RS07390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PSNIH2_RS07415	COG1454	alcohol dehydrogenase
PSNIH2_RS07415	COG1012	belongs to the aldehyde dehydrogenase family
PSNIH2_RS07420	COG2095	MarC family integral membrane protein
PSNIH2_RS07440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSNIH2_RS07445	COG0444	Belongs to the ABC transporter superfamily
PSNIH2_RS07455	COG3099	Belongs to the UPF0263 family
PSNIH2_RS07460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PSNIH2_RS07470	COG2350	Protein conserved in bacteria
PSNIH2_RS07485	COG2917	probably involved in intracellular septation
PSNIH2_RS07495	COG0727	PFAM Uncharacterised protein family (UPF0153)
PSNIH2_RS07500	COG3047	cAMP biosynthetic process
PSNIH2_RS07510	COG0159	tryptophan synthase activity
PSNIH2_RS07520	COG0134	indole-3-glycerol-phosphate synthase activity
PSNIH2_RS07520	COG0135	phosphoribosylanthranilate isomerase activity
PSNIH2_RS07525	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PSNIH2_RS07530	COG0512	Glutamine amidotransferase of anthranilate synthase
PSNIH2_RS07545	COG0009	L-threonylcarbamoyladenylate synthase
PSNIH2_RS07560	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS07565	COG0616	signal peptide processing
PSNIH2_RS07585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PSNIH2_RS07595	COG0671	phosphoesterase, PA-phosphatase related
PSNIH2_RS07600	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
PSNIH2_RS07605	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PSNIH2_RS07615	COG0023	Translation Initiation Factor
PSNIH2_RS07635	COG1024	Enoyl-CoA hydratase
PSNIH2_RS07640	COG5001	Diguanylate cyclase
PSNIH2_RS07650	COG1966	Carbon starvation protein
PSNIH2_RS07655	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
PSNIH2_RS07665	COG1263	PTS System
PSNIH2_RS07665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PSNIH2_RS07675	COG0784	Response regulator, receiver
PSNIH2_RS07675	COG0835	chemotaxis
PSNIH2_RS07680	COG2200	EAL domain
PSNIH2_RS07685	COG3182	Iron-regulated membrane protein
PSNIH2_RS07715	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PSNIH2_RS07715	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PSNIH2_RS07720	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PSNIH2_RS07730	COG4172	Belongs to the ABC transporter superfamily
PSNIH2_RS07755	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PSNIH2_RS07760	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PSNIH2_RS07765	COG1842	Phage shock protein A
PSNIH2_RS07775	COG1983	PspC domain protein
PSNIH2_RS07785	COG3106	COG3106 Predicted ATPase
PSNIH2_RS07790	COG3768	UPF0283 membrane protein
PSNIH2_RS07810	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PSNIH2_RS07815	COG4948	Mandelate Racemase Muconate Lactonizing
PSNIH2_RS07820	COG2866	Carboxypeptidase
PSNIH2_RS07825	COG4166	transmembrane transport
PSNIH2_RS07835	COG0037	tRNA processing
PSNIH2_RS07845	COG5001	Diguanylate cyclase
PSNIH2_RS07845	COG4251	negative regulation of phosphorylation
PSNIH2_RS07845	COG3706	GGDEF domain
PSNIH2_RS07845	COG2203	Gaf domain
PSNIH2_RS07865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PSNIH2_RS07870	COG2911	Protein conserved in bacteria
PSNIH2_RS07880	COG3784	Protein of unknown function (DUF1318)
PSNIH2_RS07885	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PSNIH2_RS07890	COG1643	Atp-dependent helicase
PSNIH2_RS07895	COG3591	Belongs to the peptidase S1B family
PSNIH2_RS07905	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PSNIH2_RS07910	COG2205	protein histidine kinase activity
PSNIH2_RS07915	COG0745	RESPONSE REGULATOR receiver
PSNIH2_RS07925	COG0531	amino acid
PSNIH2_RS07935	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PSNIH2_RS07940	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PSNIH2_RS07950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PSNIH2_RS07955	COG2840	Smr protein MutS2
PSNIH2_RS07960	COG0583	DNA-binding transcription factor activity
PSNIH2_RS07970	COG5383	Protein conserved in bacteria
PSNIH2_RS07980	COG0840	transmembrane signaling receptor activity
PSNIH2_RS07985	COG0583	DNA-binding transcription factor activity
PSNIH2_RS07990	COG0436	Aminotransferase
PSNIH2_RS08000	COG2195	Cleaves the N-terminal amino acid of tripeptides
PSNIH2_RS08005	COG0747	negative chemotaxis
PSNIH2_RS08010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PSNIH2_RS08015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PSNIH2_RS08015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PSNIH2_RS08020	COG2723	6-phospho-beta-galactosidase activity
PSNIH2_RS08025	COG1609	Transcriptional regulator
PSNIH2_RS08030	COG1012	belongs to the aldehyde dehydrogenase family
PSNIH2_RS08060	COG0235	Class ii aldolase
PSNIH2_RS08070	COG2814	Major facilitator Superfamily
PSNIH2_RS08080	COG0477	Major facilitator Superfamily
PSNIH2_RS08105	COG4977	sequence-specific DNA binding
PSNIH2_RS08140	COG3729	General stress protein
PSNIH2_RS08145	COG3135	benzoate transporter
PSNIH2_RS08150	COG1396	sequence-specific DNA binding
PSNIH2_RS08155	COG4772	TonB-dependent receptor
PSNIH2_RS08160	COG2084	Dehydrogenase
PSNIH2_RS08175	COG2382	esterase
PSNIH2_RS08180	COG2162	N-hydroxyarylamine O-acetyltransferase activity
PSNIH2_RS08195	COG3634	alkyl hydroperoxide reductase activity
PSNIH2_RS08215	COG2271	Major facilitator Superfamily
PSNIH2_RS08225	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PSNIH2_RS08230	COG0163	prenyltransferase activity
PSNIH2_RS08235	COG1846	Transcriptional regulator
PSNIH2_RS08245	COG2223	nitrite transmembrane transporter activity
PSNIH2_RS08250	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PSNIH2_RS08255	COG1140	nitrate reductase beta subunit
PSNIH2_RS08260	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PSNIH2_RS08265	COG2181	nitrate reductase activity
PSNIH2_RS08275	COG0778	Nitroreductase
PSNIH2_RS08280	COG2207	Transcriptional regulator
PSNIH2_RS08285	COG4221	oxidoreductase activity
PSNIH2_RS08290	COG4221	oxidoreductase activity
PSNIH2_RS08295	COG0814	amino acid
PSNIH2_RS08300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSNIH2_RS08345	COG1464	Belongs to the NlpA lipoprotein family
PSNIH2_RS08350	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
PSNIH2_RS08380	COG0339	signal peptide processing
PSNIH2_RS08390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PSNIH2_RS08400	COG0402	S-adenosylhomocysteine deaminase activity
PSNIH2_RS08405	COG4221	oxidoreductase activity
PSNIH2_RS08425	COG0477	Major facilitator Superfamily
PSNIH2_RS08450	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PSNIH2_RS08455	COG1940	carbohydrate kinase activity
PSNIH2_RS08460	COG0583	DNA-binding transcription factor activity
PSNIH2_RS08465	COG2814	Major facilitator Superfamily
PSNIH2_RS08475	COG0114	fumarate hydratase activity
PSNIH2_RS08480	COG1482	cell wall glycoprotein biosynthetic process
PSNIH2_RS08485	COG5339	Protein conserved in bacteria
PSNIH2_RS08495	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PSNIH2_RS08505	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSNIH2_RS08515	COG1879	ABC-type sugar transport system periplasmic component
PSNIH2_RS08520	COG1069	ribulokinase activity
PSNIH2_RS08525	COG2160	L-arabinose isomerase activity
PSNIH2_RS08530	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSNIH2_RS08535	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSNIH2_RS08540	COG1129	ABC transporter
PSNIH2_RS08545	COG1879	ABC-type sugar transport system periplasmic component
PSNIH2_RS08565	COG4657	Part of a membrane complex involved in electron transport
PSNIH2_RS08570	COG2878	Part of a membrane complex involved in electron transport
PSNIH2_RS08575	COG4656	Part of a membrane complex involved in electron transport
PSNIH2_RS08580	COG4658	electron transport chain
PSNIH2_RS08585	COG4659	FMN binding
PSNIH2_RS08590	COG4660	Part of a membrane complex involved in electron transport
PSNIH2_RS08595	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PSNIH2_RS08600	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PSNIH2_RS08610	COG1309	transcriptional regulator
PSNIH2_RS08615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PSNIH2_RS08620	COG3104	oligopeptide transport
PSNIH2_RS08625	COG0625	glutathione transferase activity
PSNIH2_RS08640	COG0259	pyridoxamine-phosphate oxidase activity
PSNIH2_RS08645	COG3895	Periplasmic Protein
PSNIH2_RS08650	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PSNIH2_RS08655	COG3133	Outer membrane lipoprotein
PSNIH2_RS08670	COG4989	oxidoreductase activity
PSNIH2_RS08675	COG3313	Fe-S protein
PSNIH2_RS08680	COG2194	sulfuric ester hydrolase activity
PSNIH2_RS08685	COG1309	transcriptional regulator
PSNIH2_RS08690	COG0346	lactoylglutathione lyase activity
PSNIH2_RS08700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PSNIH2_RS08705	COG0791	NLP P60 protein
PSNIH2_RS08710	COG1609	Transcriptional regulator
PSNIH2_RS08715	COG0583	DNA-binding transcription factor activity
PSNIH2_RS08720	COG2814	Major facilitator Superfamily
PSNIH2_RS08725	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PSNIH2_RS08730	COG0307	riboflavin synthase, alpha
PSNIH2_RS08765	COG1376	ErfK ybiS ycfS ynhG family protein
PSNIH2_RS08765	COG1388	LysM domain
PSNIH2_RS08780	COG0719	Fe-S assembly protein
PSNIH2_RS08785	COG0396	ATPase activity
PSNIH2_RS08790	COG0719	Fe-S assembly protein
PSNIH2_RS08795	COG0316	Belongs to the HesB IscA family
PSNIH2_RS08805	COG2050	protein possibly involved in aromatic compounds catabolism
PSNIH2_RS08810	COG0247	lactate metabolic process
PSNIH2_RS08810	COG0277	FAD linked oxidase domain protein
PSNIH2_RS08815	COG0628	permease
PSNIH2_RS08820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PSNIH2_RS08820	COG0574	Belongs to the PEP-utilizing enzyme family
PSNIH2_RS08825	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PSNIH2_RS08830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PSNIH2_RS08835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PSNIH2_RS08840	COG2200	EAL domain
PSNIH2_RS08845	COG0791	NLP P60 protein
PSNIH2_RS08855	COG0386	Belongs to the glutathione peroxidase family
PSNIH2_RS08860	COG4139	cobalamin transport
PSNIH2_RS08870	COG0776	regulation of translation
PSNIH2_RS08900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PSNIH2_RS08910	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS08910	COG3321	synthase
PSNIH2_RS08910	COG0604	alcohol dehydrogenase
PSNIH2_RS08920	COG3383	formate dehydrogenase (NAD+) activity
PSNIH2_RS08930	COG1271	oxidase subunit
PSNIH2_RS08935	COG1294	oxidase, subunit
PSNIH2_RS08940	COG3137	Salt-induced outer membrane protein
PSNIH2_RS08955	COG3001	Fructosamine kinase
PSNIH2_RS08965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PSNIH2_RS08975	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS08980	COG1988	membrane-bound metal-dependent
PSNIH2_RS08985	COG1823	symporter activity
PSNIH2_RS08990	COG0753	catalase activity
PSNIH2_RS09000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PSNIH2_RS09005	COG2814	Major facilitator Superfamily
PSNIH2_RS09010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PSNIH2_RS09015	COG0322	excinuclease ABC activity
PSNIH2_RS09020	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS09025	COG3678	ATP-independent chaperone mediated protein folding
PSNIH2_RS09030	COG2988	succinylglutamate desuccinylase activity
PSNIH2_RS09035	COG3724	N-succinylarginine dihydrolase activity
PSNIH2_RS09040	COG1012	belongs to the aldehyde dehydrogenase family
PSNIH2_RS09055	COG1271	oxidase subunit
PSNIH2_RS09060	COG1294	oxidase, subunit
PSNIH2_RS09065	COG4932	domain protein
PSNIH2_RS09070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PSNIH2_RS09070	COG1648	precorrin-2 dehydrogenase activity
PSNIH2_RS09075	COG0243	molybdopterin cofactor binding
PSNIH2_RS09080	COG2146	nitrite reductase [NAD(P)H] activity
PSNIH2_RS09080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSNIH2_RS09085	COG1116	anion transmembrane transporter activity
PSNIH2_RS09090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSNIH2_RS09095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PSNIH2_RS09105	COG3707	response regulator
PSNIH2_RS09110	COG0840	transmembrane signaling receptor activity
PSNIH2_RS09150	COG0515	serine threonine protein kinase
PSNIH2_RS09155	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
PSNIH2_RS09160	COG4572	Cation transport regulator
PSNIH2_RS09165	COG0387	Pfam Sodium calcium exchanger
PSNIH2_RS09175	COG2912	Transglutaminase-like superfamily
PSNIH2_RS09185	COG2890	protein-(glutamine-N5) methyltransferase activity
PSNIH2_RS09190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PSNIH2_RS09200	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PSNIH2_RS09225	COG0193	aminoacyl-tRNA hydrolase activity
PSNIH2_RS09235	COG0012	GTP binding
PSNIH2_RS09300	COG0753	catalase activity
PSNIH2_RS09320	COG1278	Cold shock
PSNIH2_RS09325	COG3122	Protein conserved in bacteria
PSNIH2_RS09360	COG3210	domain, Protein
PSNIH2_RS09380	COG4974	Belongs to the 'phage' integrase family
PSNIH2_RS09390	COG3210	domain, Protein
PSNIH2_RS09405	COG3210	domain, Protein
PSNIH2_RS09405	COG3210	domain, Protein
PSNIH2_RS09415	COG2831	hemolysin activation secretion protein
PSNIH2_RS09425	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS09430	COG0583	DNA-binding transcription factor activity
PSNIH2_RS09435	COG0840	transmembrane signaling receptor activity
PSNIH2_RS09460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PSNIH2_RS09460	COG0519	Catalyzes the synthesis of GMP from XMP
PSNIH2_RS09470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSNIH2_RS09475	COG3381	protein complex oligomerization
PSNIH2_RS09480	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PSNIH2_RS09505	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
PSNIH2_RS09510	COG4774	siderophore transport
PSNIH2_RS09515	COG0702	epimerase
PSNIH2_RS09520	COG1733	regulation of RNA biosynthetic process
PSNIH2_RS09525	COG2261	transglycosylase associated protein
PSNIH2_RS09530	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PSNIH2_RS09535	COG0668	transmembrane transport
PSNIH2_RS09545	COG1619	proteins homologs of microcin C7 resistance protein MccF
PSNIH2_RS09605	COG1652	LysM domain
PSNIH2_RS09625	COG2353	YceI-like domain
PSNIH2_RS09630	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PSNIH2_RS09635	COG4977	sequence-specific DNA binding
PSNIH2_RS09650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PSNIH2_RS09655	COG1113	amino acid transport
PSNIH2_RS09660	COG1064	alcohol dehydrogenase
PSNIH2_RS09685	COG3729	General stress protein
PSNIH2_RS09715	COG1464	Belongs to the NlpA lipoprotein family
PSNIH2_RS09725	COG2011	ABC-type metal ion transport system permease component
PSNIH2_RS09750	COG1280	lysine exporter protein (LysE YggA)
PSNIH2_RS09755	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PSNIH2_RS09765	COG0668	transmembrane transport
PSNIH2_RS09790	COG1349	DNA-binding transcription factor activity
PSNIH2_RS09795	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
PSNIH2_RS09800	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS09820	COG0583	DNA-binding transcription factor activity
PSNIH2_RS09840	COG4993	Dehydrogenase
PSNIH2_RS09850	COG0300	oxidoreductase activity
PSNIH2_RS09855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PSNIH2_RS09865	COG0583	DNA-binding transcription factor activity
PSNIH2_RS09885	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS09895	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
PSNIH2_RS09930	COG2203	Gaf domain
PSNIH2_RS09930	COG5001	Diguanylate cyclase
PSNIH2_RS09930	COG4251	negative regulation of phosphorylation
PSNIH2_RS09930	COG3706	GGDEF domain
PSNIH2_RS09935	COG0814	amino acid
PSNIH2_RS09950	COG0583	DNA-binding transcription factor activity
PSNIH2_RS09980	COG0456	acetyltransferase
PSNIH2_RS10005	COG1609	Transcriptional regulator
PSNIH2_RS10015	COG2223	nitrite transmembrane transporter activity
PSNIH2_RS10055	COG0538	isocitrate dehydrogenase activity
PSNIH2_RS10070	COG0482	sulfurtransferase activity
PSNIH2_RS10075	COG2915	High frequency lysogenization protein hflD homolog
PSNIH2_RS10080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PSNIH2_RS10090	COG2205	protein histidine kinase activity
PSNIH2_RS10095	COG2850	peptidyl-arginine hydroxylation
PSNIH2_RS10115	COG1177	transmembrane transport
PSNIH2_RS10120	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PSNIH2_RS10125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PSNIH2_RS10130	COG1940	carbohydrate kinase activity
PSNIH2_RS10135	COG4591	ABC-type transport system involved in lipoprotein release permease component
PSNIH2_RS10145	COG4591	ABC-type transport system involved in lipoprotein release permease component
PSNIH2_RS10155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PSNIH2_RS10160	COG3134	Outer membrane lipoprotein
PSNIH2_RS10170	COG1252	NADH dehydrogenase
PSNIH2_RS10180	COG1472	Belongs to the glycosyl hydrolase 3 family
PSNIH2_RS10190	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
PSNIH2_RS10195	COG5633	Lipoprotein
PSNIH2_RS10200	COG0537	adenosine 5'-monophosphoramidase activity
PSNIH2_RS10210	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
PSNIH2_RS10230	COG1263	PTS System
PSNIH2_RS10230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PSNIH2_RS10235	COG0084	hydrolase, TatD family'
PSNIH2_RS10240	COG0470	DNA polymerase III
PSNIH2_RS10245	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PSNIH2_RS10250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PSNIH2_RS10255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PSNIH2_RS10260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PSNIH2_RS10275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PSNIH2_RS10280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PSNIH2_RS10285	COG0416	fatty acid biosynthetic process
PSNIH2_RS10290	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PSNIH2_RS10295	COG1399	metal-binding, possibly nucleic acid-binding protein
PSNIH2_RS10305	COG0564	pseudouridine synthase activity
PSNIH2_RS10310	COG1530	ribonuclease E activity
PSNIH2_RS10320	COG1256	bacterial-type flagellum assembly
PSNIH2_RS10350	COG1749	Flagellar hook protein flgE
PSNIH2_RS10360	COG1558	bacterial-type flagellum-dependent cell motility
PSNIH2_RS10365	COG1815	bacterial-type flagellum-dependent cell motility
PSNIH2_RS10370	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
PSNIH2_RS10380	COG3418	PFAM FlgN family protein
PSNIH2_RS10385	COG0728	peptidoglycan biosynthetic process
PSNIH2_RS10395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PSNIH2_RS10405	COG2999	glutathione oxidoreductase activity
PSNIH2_RS10415	COG0418	dihydroorotase activity
PSNIH2_RS10440	COG0477	Major facilitator Superfamily
PSNIH2_RS10445	COG3038	cytochrome b561
PSNIH2_RS10450	COG2353	YceI-like domain
PSNIH2_RS10455	COG1054	Belongs to the UPF0176 family
PSNIH2_RS10460	COG1902	pentaerythritol trinitrate reductase activity
PSNIH2_RS10465	COG1560	Kdo2-lipid A biosynthetic process
PSNIH2_RS10475	COG5645	(Lipo)protein
PSNIH2_RS10495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PSNIH2_RS10500	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
PSNIH2_RS10545	COG0659	secondary active sulfate transmembrane transporter activity
PSNIH2_RS10595	COG1136	(ABC) transporter
PSNIH2_RS10610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PSNIH2_RS10620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PSNIH2_RS10625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSNIH2_RS10635	COG0736	holo-[acyl-carrier-protein] synthase activity
PSNIH2_RS10640	COG2831	hemolysin activation secretion protein
PSNIH2_RS10645	COG3210	domain, Protein
PSNIH2_RS10655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PSNIH2_RS10665	COG2197	response regulator
PSNIH2_RS10675	COG3136	membrane protein required for alginate biosynthesis
PSNIH2_RS10685	COG2197	response regulator
PSNIH2_RS10695	COG1113	amino acid transport
PSNIH2_RS10705	COG1309	transcriptional regulator
PSNIH2_RS10720	COG0251	oxidation-reduction process
PSNIH2_RS10725	COG2267	carboxylic ester hydrolase activity
PSNIH2_RS10730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PSNIH2_RS10735	COG2233	PERMEase
PSNIH2_RS10755	COG1012	belongs to the aldehyde dehydrogenase family
PSNIH2_RS10775	COG0670	Belongs to the BI1 family
PSNIH2_RS10780	COG2920	part of a sulfur-relay system
PSNIH2_RS10790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PSNIH2_RS10800	COG1832	CoA-binding protein
PSNIH2_RS10815	COG0210	DNA helicase
PSNIH2_RS10820	COG3304	Inner membrane component domain
PSNIH2_RS10825	COG1289	transmembrane transporter activity
PSNIH2_RS10830	COG3070	regulator of competence-specific genes
PSNIH2_RS10845	COG3120	sequence-specific DNA binding
PSNIH2_RS10850	COG1067	ATP-dependent peptidase activity
PSNIH2_RS10855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSNIH2_RS10860	COG3009	Protein conserved in bacteria
PSNIH2_RS10865	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PSNIH2_RS10865	COG3008	intermembrane lipid transfer
PSNIH2_RS10870	COG2995	paraquat-inducible protein a
PSNIH2_RS10875	COG0488	(ABC) transporter
PSNIH2_RS10880	COG0116	Belongs to the methyltransferase superfamily
PSNIH2_RS10880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PSNIH2_RS10885	COG3217	Mosc domain protein beta barrel domain protein
PSNIH2_RS10885	COG0633	Ferredoxin
PSNIH2_RS10895	COG0167	dihydroorotate dehydrogenase activity
PSNIH2_RS10900	COG0431	NADPH-dependent FMN reductase
PSNIH2_RS10905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PSNIH2_RS10915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSNIH2_RS10925	COG0308	aminopeptidase N
PSNIH2_RS10930	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PSNIH2_RS10945	COG1448	Aminotransferase
PSNIH2_RS10950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PSNIH2_RS10955	COG3108	Peptidase M15
PSNIH2_RS10960	COG2989	Protein conserved in bacteria
PSNIH2_RS10970	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
PSNIH2_RS10975	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
PSNIH2_RS10980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PSNIH2_RS10985	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PSNIH2_RS10990	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PSNIH2_RS10995	COG2835	tetraacyldisaccharide 4'-kinase activity
PSNIH2_RS11000	COG3214	Protein conserved in bacteria
PSNIH2_RS11015	COG2333	competence protein COMEC
PSNIH2_RS11015	COG0658	competence protein
PSNIH2_RS11025	COG0539	negative regulation of cytoplasmic translation
PSNIH2_RS11040	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PSNIH2_RS11045	COG1944	ATP diphosphatase activity
PSNIH2_RS11050	COG2116	formate transmembrane transporter activity
PSNIH2_RS11055	COG1882	Formate acetyltransferase
PSNIH2_RS11060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PSNIH2_RS11065	COG0477	Major facilitator Superfamily
PSNIH2_RS11070	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PSNIH2_RS11075	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PSNIH2_RS11080	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PSNIH2_RS11085	COG1674	ftsk spoiiie
PSNIH2_RS11085	COG3107	peptidoglycan biosynthetic process
PSNIH2_RS11095	COG0492	ferredoxin-NADP+ reductase activity
PSNIH2_RS11100	COG4988	ABC transporter
PSNIH2_RS11105	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PSNIH2_RS11110	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PSNIH2_RS11115	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PSNIH2_RS11120	COG0542	response to heat
PSNIH2_RS11125	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PSNIH2_RS11130	COG1278	Cold shock
PSNIH2_RS11135	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
PSNIH2_RS11140	COG2431	L-lysine efflux transmembrane transporter activity
PSNIH2_RS11150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PSNIH2_RS11155	COG0028	Belongs to the TPP enzyme family
PSNIH2_RS11160	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PSNIH2_RS11165	COG3023	N-Acetylmuramoyl-L-alanine amidase
PSNIH2_RS11170	COG0393	Putative heavy-metal-binding
PSNIH2_RS11180	COG1126	abc transporter atp-binding protein
PSNIH2_RS11185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSNIH2_RS11190	COG4215	(ABC) transporter
PSNIH2_RS11195	COG4160	amino acid transport
PSNIH2_RS11200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSNIH2_RS11215	COG1177	transmembrane transport
PSNIH2_RS11220	COG1176	ABC-type spermidine putrescine transport system, permease component I
PSNIH2_RS11225	COG3842	ATPase activity
PSNIH2_RS11230	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PSNIH2_RS11245	COG0778	Nitroreductase
PSNIH2_RS11275	COG0671	phosphoesterase, PA-phosphatase related
PSNIH2_RS11280	COG0814	amino acid
PSNIH2_RS11285	COG1686	Belongs to the peptidase S11 family
PSNIH2_RS11295	COG2133	pyrroloquinoline quinone binding
PSNIH2_RS11305	COG0673	inositol 2-dehydrogenase activity
PSNIH2_RS11330	COG0601	transmembrane transport
PSNIH2_RS11335	COG0747	negative chemotaxis
PSNIH2_RS11340	COG4172	Belongs to the ABC transporter superfamily
PSNIH2_RS11345	COG1446	asparaginase
PSNIH2_RS11355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PSNIH2_RS11360	COG5001	Diguanylate cyclase
PSNIH2_RS11360	COG4251	negative regulation of phosphorylation
PSNIH2_RS11360	COG2203	Gaf domain
PSNIH2_RS11360	COG3706	GGDEF domain
PSNIH2_RS11365	COG0488	(ABC) transporter
PSNIH2_RS11370	COG2814	Major facilitator Superfamily
PSNIH2_RS11380	COG2814	Major facilitator Superfamily
PSNIH2_RS11385	COG1566	PFAM secretion protein HlyD family protein
PSNIH2_RS11390	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PSNIH2_RS11395	COG1321	iron dependent repressor
PSNIH2_RS11405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PSNIH2_RS11415	COG0783	Belongs to the Dps family
PSNIH2_RS11420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSNIH2_RS11425	COG0765	amino acid transport
PSNIH2_RS11430	COG1126	abc transporter atp-binding protein
PSNIH2_RS11435	COG0668	transmembrane transport
PSNIH2_RS11440	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PSNIH2_RS11445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PSNIH2_RS11450	COG0667	Aldo Keto reductase
PSNIH2_RS11455	COG1473	amidohydrolase
PSNIH2_RS11460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PSNIH2_RS11480	COG0789	Transcriptional regulator
PSNIH2_RS11485	COG1174	glycine betaine transport
PSNIH2_RS11490	COG1125	glycine betaine transport
PSNIH2_RS11495	COG1174	glycine betaine transport
PSNIH2_RS11500	COG1732	Glycine betaine
PSNIH2_RS11505	COG0477	Major facilitator Superfamily
PSNIH2_RS11510	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
PSNIH2_RS11530	COG3685	Protein conserved in bacteria
PSNIH2_RS11535	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS11555	COG3265	gluconokinase activity
PSNIH2_RS11560	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS11565	COG1609	Transcriptional regulator
PSNIH2_RS11570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PSNIH2_RS11590	COG5001	Diguanylate cyclase
PSNIH2_RS11600	COG1472	Belongs to the glycosyl hydrolase 3 family
PSNIH2_RS11605	COG0277	FAD linked oxidase domain protein
PSNIH2_RS11610	COG1511	domain protein
PSNIH2_RS11610	COG3264	Mechanosensitive ion channel
PSNIH2_RS11620	COG1686	Belongs to the peptidase S11 family
PSNIH2_RS11630	COG0586	Pfam SNARE associated Golgi protein
PSNIH2_RS11635	COG0390	transport system, permease component
PSNIH2_RS11640	COG4619	ABC transporter
PSNIH2_RS11645	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS11650	COG3387	PFAM Glycoside hydrolase 15-related
PSNIH2_RS11655	COG1376	ErfK ybiS ycfS ynhG family protein
PSNIH2_RS11660	COG0306	phosphate transporter
PSNIH2_RS11665	COG0477	Major facilitator Superfamily
PSNIH2_RS11670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PSNIH2_RS11675	COG0513	Belongs to the DEAD box helicase family
PSNIH2_RS11685	COG3568	Endonuclease Exonuclease Phosphatase
PSNIH2_RS11690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PSNIH2_RS11695	COG0392	lysyltransferase activity
PSNIH2_RS11700	COG0670	Belongs to the BI1 family
PSNIH2_RS11725	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PSNIH2_RS11730	COG0315	cyclic pyranopterin monophosphate synthase activity
PSNIH2_RS11735	COG0521	Mo-molybdopterin cofactor biosynthetic process
PSNIH2_RS11770	COG0156	8-amino-7-oxononanoate synthase activity
PSNIH2_RS11775	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PSNIH2_RS11785	COG2130	NADP-dependent
PSNIH2_RS11810	COG2706	6-phosphogluconolactonase activity
PSNIH2_RS11815	COG0561	phosphatase activity
PSNIH2_RS11825	COG4149	molybdate abc transporter
PSNIH2_RS11830	COG0725	ABC transporter, periplasmic molybdate-binding protein
PSNIH2_RS11840	COG3585	molybdate ion transport
PSNIH2_RS11840	COG2005	Transcriptional regulator
PSNIH2_RS11845	COG1119	ATPase activity
PSNIH2_RS11850	COG1085	galactose-1-phosphate uridylyltransferase
PSNIH2_RS11860	COG2017	converts alpha-aldose to the beta-anomer
PSNIH2_RS11865	COG0588	phosphoglycerate mutase activity
PSNIH2_RS11870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PSNIH2_RS11885	COG0784	Response regulator, receiver
PSNIH2_RS11885	COG2198	Histidine kinase
PSNIH2_RS11885	COG5002	protein histidine kinase activity
PSNIH2_RS11890	COG1230	cation diffusion facilitator family transporter
PSNIH2_RS11900	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PSNIH2_RS11905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PSNIH2_RS11940	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PSNIH2_RS11945	COG2885	chlorophyll binding
PSNIH2_RS11950	COG0823	Involved in the tonB-independent uptake of proteins
PSNIH2_RS11955	COG3064	Membrane
PSNIH2_RS11960	COG0848	biopolymer transport protein
PSNIH2_RS11965	COG0811	peptide transport
PSNIH2_RS11970	COG0824	Thioesterase
PSNIH2_RS11975	COG3790	cyd operon protein YbgE
PSNIH2_RS11980	COG1294	oxidase, subunit
PSNIH2_RS11985	COG1271	oxidase subunit
PSNIH2_RS11990	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PSNIH2_RS11995	COG0045	succinate-CoA ligase (ADP-forming) activity
PSNIH2_RS12000	COG0508	dehydrogenase complex catalyzes the overall conversion of
PSNIH2_RS12005	COG0567	Dehydrogenase, E1 component
PSNIH2_RS12010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PSNIH2_RS12015	COG1053	succinate dehydrogenase
PSNIH2_RS12020	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PSNIH2_RS12025	COG2009	succinate dehydrogenase
PSNIH2_RS12030	COG0372	Belongs to the citrate synthase family
PSNIH2_RS12040	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PSNIH2_RS12060	COG1984	allophanate hydrolase subunit 2
PSNIH2_RS12065	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PSNIH2_RS12080	COG3272	Protein of unknown function (DUF1722)
PSNIH2_RS12090	COG0745	RESPONSE REGULATOR receiver
PSNIH2_RS12095	COG0033	Phosphoglucomutase
PSNIH2_RS12100	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
PSNIH2_RS12105	COG0596	Alpha beta hydrolase
PSNIH2_RS12120	COG0735	belongs to the Fur family
PSNIH2_RS12135	COG0814	amino acid
PSNIH2_RS12140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PSNIH2_RS12145	COG1263	PTS System
PSNIH2_RS12145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PSNIH2_RS12145	COG2190	(PTS) system
PSNIH2_RS12155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PSNIH2_RS12160	COG1940	carbohydrate kinase activity
PSNIH2_RS12160	COG1846	Transcriptional regulator
PSNIH2_RS12165	COG0367	asparagine synthase
PSNIH2_RS12205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSNIH2_RS12215	COG1702	phosphate starvation-inducible protein PhoH
PSNIH2_RS12220	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PSNIH2_RS12230	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PSNIH2_RS12240	COG0765	amino acid transport
PSNIH2_RS12245	COG0765	amino acid transport
PSNIH2_RS12250	COG1126	abc transporter atp-binding protein
PSNIH2_RS12255	COG2888	peptidyl-tyrosine sulfation
PSNIH2_RS12260	COG0495	leucyl-tRNA aminoacylation
PSNIH2_RS12265	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
PSNIH2_RS12270	COG1466	dna polymerase III delta subunit
PSNIH2_RS12280	COG0799	negative regulation of ribosome biogenesis
PSNIH2_RS12285	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PSNIH2_RS12290	COG0768	penicillin binding
PSNIH2_RS12295	COG0772	Belongs to the SEDS family
PSNIH2_RS12300	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PSNIH2_RS12305	COG1686	Belongs to the peptidase S11 family
PSNIH2_RS12315	COG0321	lipoyl(octanoyl) transferase activity
PSNIH2_RS12320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PSNIH2_RS12330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PSNIH2_RS12335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PSNIH2_RS12355	COG2610	gluconate transmembrane transporter activity
PSNIH2_RS12360	COG1454	alcohol dehydrogenase
PSNIH2_RS12365	COG0561	phosphatase activity
PSNIH2_RS12375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PSNIH2_RS12385	COG0582	viral genome integration into host DNA
PSNIH2_RS12400	COG2501	S4 domain
PSNIH2_RS12405	COG0673	inositol 2-dehydrogenase activity
PSNIH2_RS12410	COG1349	DNA-binding transcription factor activity
PSNIH2_RS12415	COG0215	cysteine-tRNA ligase activity
PSNIH2_RS12420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PSNIH2_RS12430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PSNIH2_RS12435	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PSNIH2_RS12440	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PSNIH2_RS12445	COG4181	ATPase activity
PSNIH2_RS12450	COG2755	lipolytic protein G-D-S-L family
PSNIH2_RS12455	COG0300	oxidoreductase activity
PSNIH2_RS12460	COG3118	belongs to the thioredoxin family
PSNIH2_RS12465	COG0330	HflC and HflK could
PSNIH2_RS12470	COG1585	Membrane protein implicated in regulation of membrane protease activity
PSNIH2_RS12480	COG2217	Heavy metal translocating P-type atpase
PSNIH2_RS12485	COG3735	TraB family
PSNIH2_RS12495	COG0583	DNA-binding transcription factor activity
PSNIH2_RS12505	COG0737	Belongs to the 5'-nucleotidase family
PSNIH2_RS12510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PSNIH2_RS12510	COG4651	solute:proton antiporter activity
PSNIH2_RS12515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PSNIH2_RS12520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PSNIH2_RS12525	COG0563	adenylate kinase activity
PSNIH2_RS12535	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PSNIH2_RS12540	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PSNIH2_RS12550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PSNIH2_RS12555	COG2832	Protein of unknown function (DUF454)
PSNIH2_RS12565	COG1309	transcriptional regulator
PSNIH2_RS12570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSNIH2_RS12575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PSNIH2_RS12580	COG0254	rRNA binding
PSNIH2_RS12585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PSNIH2_RS12605	COG3695	enzyme binding
PSNIH2_RS12610	COG3126	Type III secretion system lipoprotein chaperone (YscW)
PSNIH2_RS12615	COG1946	Acyl-CoA thioesterase
PSNIH2_RS12620	COG0004	ammonium transporteR
PSNIH2_RS12625	COG0347	Belongs to the P(II) protein family
PSNIH2_RS12630	COG1132	(ABC) transporter
PSNIH2_RS12635	COG1132	(ABC) transporter
PSNIH2_RS12640	COG1522	sequence-specific DNA binding
PSNIH2_RS12655	COG0824	Thioesterase
PSNIH2_RS12660	COG1555	photosystem II stabilization
PSNIH2_RS12665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PSNIH2_RS12670	COG0776	regulation of translation
PSNIH2_RS12695	COG0271	Belongs to the BolA IbaG family
PSNIH2_RS12700	COG3056	Lipoprotein
PSNIH2_RS12705	COG2223	nitrite transmembrane transporter activity
PSNIH2_RS12710	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PSNIH2_RS12715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PSNIH2_RS12720	COG1845	cytochrome c oxidase, subunit III
PSNIH2_RS12725	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PSNIH2_RS12730	COG0109	protoheme IX farnesyltransferase activity
PSNIH2_RS12735	COG2814	Major facilitator Superfamily
PSNIH2_RS12740	COG1666	GTP binding
PSNIH2_RS12745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PSNIH2_RS12755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PSNIH2_RS12755	COG0301	tRNA thio-modification
PSNIH2_RS12765	COG0142	geranyltranstransferase activity
PSNIH2_RS12770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PSNIH2_RS12780	COG0596	Alpha beta hydrolase
PSNIH2_RS12785	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PSNIH2_RS12790	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PSNIH2_RS12795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PSNIH2_RS12800	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PSNIH2_RS12805	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PSNIH2_RS12805	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PSNIH2_RS12810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PSNIH2_RS12815	COG4238	major outer membrane lipoprotein
PSNIH2_RS12820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PSNIH2_RS12825	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PSNIH2_RS12830	COG1862	Preprotein translocase
PSNIH2_RS12845	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
PSNIH2_RS12850	COG0668	transmembrane transport
PSNIH2_RS12875	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PSNIH2_RS12890	COG0745	RESPONSE REGULATOR receiver
PSNIH2_RS12895	COG0420	3'-5' exonuclease activity
PSNIH2_RS12900	COG0419	ATPase involved in DNA repair
PSNIH2_RS12910	COG1940	carbohydrate kinase activity
PSNIH2_RS12915	COG2974	May be involved in recombination
PSNIH2_RS12925	COG4126	flavin adenine dinucleotide binding
PSNIH2_RS12935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PSNIH2_RS12940	COG3416	Protein conserved in bacteria
PSNIH2_RS12950	COG2323	membrane
PSNIH2_RS12960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PSNIH2_RS12970	COG1278	Cold shock
PSNIH2_RS12985	COG0456	acetyltransferase
PSNIH2_RS12995	COG5001	Diguanylate cyclase
PSNIH2_RS13005	COG0747	negative chemotaxis
PSNIH2_RS13010	COG0601	transmembrane transport
PSNIH2_RS13015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSNIH2_RS13020	COG0444	Belongs to the ABC transporter superfamily
PSNIH2_RS13055	COG2194	sulfuric ester hydrolase activity
PSNIH2_RS13060	COG1012	belongs to the aldehyde dehydrogenase family
PSNIH2_RS13070	COG2155	Conserved Protein
PSNIH2_RS13075	COG1064	alcohol dehydrogenase
PSNIH2_RS13080	COG1733	regulation of RNA biosynthetic process
PSNIH2_RS13085	COG0561	phosphatase activity
PSNIH2_RS13090	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS13095	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PSNIH2_RS13115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PSNIH2_RS13130	COG2211	Major facilitator Superfamily
PSNIH2_RS13135	COG3604	Transcriptional regulator
PSNIH2_RS13155	COG2214	Heat shock protein DnaJ domain protein
PSNIH2_RS13160	COG0443	Heat shock 70 kDa protein
PSNIH2_RS13180	COG4605	iron ion homeostasis
PSNIH2_RS13185	COG4604	ABC transporter, ATP-binding protein
PSNIH2_RS13190	COG3615	Tellurite resistance protein tehB
PSNIH2_RS13195	COG0513	Belongs to the DEAD box helicase family
PSNIH2_RS13215	COG0598	Magnesium transport protein CorA
PSNIH2_RS13220	COG1609	Transcriptional regulator
PSNIH2_RS13225	COG2190	(PTS) system
PSNIH2_RS13225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PSNIH2_RS13225	COG1263	PTS System
PSNIH2_RS13230	COG0803	Belongs to the bacterial solute-binding protein 9 family
PSNIH2_RS13235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PSNIH2_RS13240	COG1121	(ABC) transporter
PSNIH2_RS13250	COG1882	Formate acetyltransferase
PSNIH2_RS13255	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PSNIH2_RS13260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PSNIH2_RS13270	COG1349	DNA-binding transcription factor activity
PSNIH2_RS13275	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PSNIH2_RS13295	COG0667	Aldo Keto reductase
PSNIH2_RS13310	COG2246	polysaccharide biosynthetic process
PSNIH2_RS13340	COG0741	lytic transglycosylase activity
PSNIH2_RS13580	COG0582	viral genome integration into host DNA
PSNIH2_RS13590	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PSNIH2_RS13595	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PSNIH2_RS13610	COG1073	alpha beta
PSNIH2_RS13615	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
PSNIH2_RS13620	COG2195	Cleaves the N-terminal amino acid of tripeptides
PSNIH2_RS13625	COG1129	ABC transporter
PSNIH2_RS13630	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSNIH2_RS13645	COG3034	peptidoglycan biosynthetic process
PSNIH2_RS13650	COG0121	glutamine amidotransferase
PSNIH2_RS13655	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PSNIH2_RS13660	COG1960	acyl-CoA dehydrogenase activity
PSNIH2_RS13665	COG1518	maintenance of DNA repeat elements
PSNIH2_RS13680	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PSNIH2_RS13690	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PSNIH2_RS13695	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
PSNIH2_RS13705	COG0436	Aminotransferase
PSNIH2_RS13710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PSNIH2_RS13715	COG2233	PERMEase
PSNIH2_RS13720	COG2351	hydroxyisourate hydrolase activity
PSNIH2_RS13735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PSNIH2_RS13740	COG1126	abc transporter atp-binding protein
PSNIH2_RS13745	COG0765	amino acid transport
PSNIH2_RS13800	COG1953	Uracil, thiamine, allantoin
PSNIH2_RS13810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PSNIH2_RS13820	COG2226	methyltransferase
PSNIH2_RS13825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PSNIH2_RS13830	COG1388	LysM domain
PSNIH2_RS13830	COG0741	lytic transglycosylase activity
PSNIH2_RS13835	COG3021	interspecies interaction between organisms
PSNIH2_RS13840	COG0583	DNA-binding transcription factor activity
PSNIH2_RS13875	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PSNIH2_RS13885	COG2011	ABC-type metal ion transport system permease component
PSNIH2_RS13900	COG1720	tRNA m6t6A37 methyltransferase activity
PSNIH2_RS13910	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PSNIH2_RS13920	COG4568	rho-dependent transcription termination
PSNIH2_RS13930	COG0037	tRNA processing
PSNIH2_RS13935	COG0346	lactoylglutathione lyase activity
PSNIH2_RS13940	COG1982	Orn Lys Arg decarboxylase major
PSNIH2_RS13945	COG0825	malonyl-CoA metabolic process
PSNIH2_RS13950	COG0587	DNA-directed DNA polymerase activity
PSNIH2_RS13955	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PSNIH2_RS13960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PSNIH2_RS13970	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSNIH2_RS13975	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PSNIH2_RS13980	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
PSNIH2_RS13985	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PSNIH2_RS13995	COG0575	Belongs to the CDS family
PSNIH2_RS14000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PSNIH2_RS14005	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PSNIH2_RS14015	COG0528	UMP kinase activity
PSNIH2_RS14020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PSNIH2_RS14035	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PSNIH2_RS14050	COG3835	regulator
PSNIH2_RS14060	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PSNIH2_RS14065	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PSNIH2_RS14070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PSNIH2_RS14075	COG0316	Belongs to the HesB IscA family
PSNIH2_RS14090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PSNIH2_RS14095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PSNIH2_RS14100	COG1120	ATPase activity
PSNIH2_RS14105	COG4774	siderophore transport
PSNIH2_RS14110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PSNIH2_RS14115	COG1643	Atp-dependent helicase
PSNIH2_RS14120	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PSNIH2_RS14125	COG1489	DNA binding
PSNIH2_RS14130	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PSNIH2_RS14145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PSNIH2_RS14150	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PSNIH2_RS14155	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PSNIH2_RS14160	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PSNIH2_RS14180	COG0842	Transport permease protein
PSNIH2_RS14185	COG1131	(ABC) transporter
PSNIH2_RS14190	COG0288	reversible hydration of carbon dioxide
PSNIH2_RS14195	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PSNIH2_RS14210	COG2132	Multicopper oxidase
PSNIH2_RS14220	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PSNIH2_RS14230	COG1349	DNA-binding transcription factor activity
PSNIH2_RS14235	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PSNIH2_RS14245	COG1454	alcohol dehydrogenase
PSNIH2_RS14250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSNIH2_RS14265	COG2731	YhcH YjgK YiaL family protein
PSNIH2_RS14280	COG3210	domain, Protein
PSNIH2_RS14280	COG3468	outer membrane autotransporter barrel domain protein
PSNIH2_RS14295	COG3479	Phenolic acid decarboxylase
PSNIH2_RS14305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PSNIH2_RS14310	COG0508	dehydrogenase complex catalyzes the overall conversion of
PSNIH2_RS14315	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PSNIH2_RS14320	COG2186	Transcriptional regulator
PSNIH2_RS14330	COG2211	Major facilitator Superfamily
PSNIH2_RS14335	COG3940	Belongs to the glycosyl hydrolase 43 family
PSNIH2_RS14340	COG3725	Membrane protein required for beta-lactamase induction
PSNIH2_RS14345	COG3023	N-Acetylmuramoyl-L-alanine amidase
PSNIH2_RS14355	COG4969	Belongs to the N-Me-Phe pilin family
PSNIH2_RS14360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PSNIH2_RS14365	COG1459	type II secretion system
PSNIH2_RS14370	COG0516	GMP reductase activity
PSNIH2_RS14380	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
PSNIH2_RS14390	COG0494	nUDIX hydrolase
PSNIH2_RS14400	COG3157	Type VI secretion system effector, Hcp
PSNIH2_RS14420	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PSNIH2_RS14425	COG0849	cell division
PSNIH2_RS14435	COG1181	Belongs to the D-alanine--D-alanine ligase family
PSNIH2_RS14440	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PSNIH2_RS14445	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PSNIH2_RS14450	COG0772	Belongs to the SEDS family
PSNIH2_RS14460	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PSNIH2_RS14465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PSNIH2_RS14470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PSNIH2_RS14475	COG0768	penicillin binding
PSNIH2_RS14480	COG3116	cell division
PSNIH2_RS14485	COG0275	rRNA processing
PSNIH2_RS14490	COG2001	Belongs to the MraZ family
PSNIH2_RS14505	COG0028	Belongs to the TPP enzyme family
PSNIH2_RS14510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PSNIH2_RS14520	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PSNIH2_RS14525	COG0066	3-isopropylmalate dehydratase activity
PSNIH2_RS14530	COG2814	Major facilitator Superfamily
PSNIH2_RS14535	COG4533	DNA binding
PSNIH2_RS14545	COG1178	ABC-type Fe3 transport system permease component
PSNIH2_RS14550	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
PSNIH2_RS14555	COG0586	Pfam SNARE associated Golgi protein
PSNIH2_RS14570	COG0417	DNA replication proofreading
PSNIH2_RS14575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PSNIH2_RS14580	COG0564	pseudouridine synthase activity
PSNIH2_RS14585	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PSNIH2_RS14600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PSNIH2_RS14605	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PSNIH2_RS14615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PSNIH2_RS14655	COG0505	Belongs to the CarA family
PSNIH2_RS14660	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PSNIH2_RS14665	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PSNIH2_RS14670	COG1047	Peptidyl-prolyl cis-trans
PSNIH2_RS14675	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PSNIH2_RS14680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PSNIH2_RS14685	COG0196	riboflavin kinase activity
PSNIH2_RS14700	COG0583	DNA-binding transcription factor activity
PSNIH2_RS14720	COG1584	GPR1 FUN34 yaaH family protein
PSNIH2_RS14730	COG0521	Mo-molybdopterin cofactor biosynthetic process
PSNIH2_RS14755	COG0460	homoserine dehydrogenase
PSNIH2_RS14755	COG0527	aspartate kinase activity
PSNIH2_RS14760	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
PSNIH2_RS14765	COG0745	RESPONSE REGULATOR receiver
PSNIH2_RS14770	COG3045	CreA protein
PSNIH2_RS14775	COG2207	Transcriptional regulator
PSNIH2_RS14775	COG3708	Transcriptional regulator
PSNIH2_RS14780	COG0406	alpha-ribazole phosphatase activity
PSNIH2_RS14785	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
PSNIH2_RS14795	COG0741	lytic transglycosylase activity
PSNIH2_RS14800	COG1349	DNA-binding transcription factor activity
PSNIH2_RS14805	COG0488	(ABC) transporter
PSNIH2_RS14830	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PSNIH2_RS14835	COG0560	Phosphoserine phosphatase
PSNIH2_RS14840	COG3726	membrane protein affecting hemolysin expression
PSNIH2_RS14845	COG0813	purine-nucleoside phosphorylase activity
PSNIH2_RS14850	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PSNIH2_RS14865	COG0084	hydrolase, TatD family'
PSNIH2_RS14870	COG4667	esterase of the alpha-beta hydrolase superfamily
PSNIH2_RS14880	COG2823	Periplasmic or secreted lipoprotein
PSNIH2_RS14885	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PSNIH2_RS14910	COG1397	ADP-ribosylglycohydrolase
PSNIH2_RS14930	COG3209	COG3209 Rhs family protein
PSNIH2_RS14975	COG0515	serine threonine protein kinase
PSNIH2_RS15095	COG1011	Hydrolase
PSNIH2_RS15100	COG0456	acetyltransferase
PSNIH2_RS15105	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
PSNIH2_RS15110	COG2813	Specifically methylates the guanine in position
PSNIH2_RS15135	COG3706	GGDEF domain
PSNIH2_RS15140	COG4114	ferric iron reductase
PSNIH2_RS15145	COG0442	prolyl-tRNA aminoacylation
PSNIH2_RS15160	COG0671	phosphoesterase, PA-phosphatase related
PSNIH2_RS15175	COG0840	transmembrane signaling receptor activity
PSNIH2_RS15185	COG1942	4-Oxalocrotonate Tautomerase
PSNIH2_RS15190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PSNIH2_RS15205	COG1609	Transcriptional regulator
PSNIH2_RS15215	COG0765	amino acid transport
PSNIH2_RS15220	COG1126	abc transporter atp-binding protein
PSNIH2_RS15225	COG0673	inositol 2-dehydrogenase activity
PSNIH2_RS15235	COG5455	response to cobalt ion
PSNIH2_RS15245	COG2226	methyltransferase
PSNIH2_RS15255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PSNIH2_RS15260	COG3716	PTS system mannose fructose sorbose family IID component
PSNIH2_RS15265	COG3715	PTS system
PSNIH2_RS15280	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PSNIH2_RS15280	COG3933	PFAM sigma-54 factor interaction domain-containing protein
PSNIH2_RS15315	COG4669	(LipO)protein
PSNIH2_RS15355	COG4792	protein secretion
PSNIH2_RS15365	COG4794	Type iii secretion
PSNIH2_RS15420	COG2197	response regulator
PSNIH2_RS15425	COG1472	Belongs to the glycosyl hydrolase 3 family
PSNIH2_RS15430	COG2211	Major facilitator Superfamily
PSNIH2_RS15445	COG2723	6-phospho-beta-galactosidase activity
PSNIH2_RS15450	COG1263	PTS System
PSNIH2_RS15450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PSNIH2_RS15455	COG1609	Transcriptional regulator
PSNIH2_RS15495	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
PSNIH2_RS15515	COG3318	Belongs to the UPF0149 family
PSNIH2_RS15515	COG3012	SEC-C Motif Domain Protein
PSNIH2_RS15520	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
PSNIH2_RS15540	COG2003	Belongs to the UPF0758 family
PSNIH2_RS15565	COG2378	regulation of single-species biofilm formation
PSNIH2_RS15570	COG3596	GTP binding
PSNIH2_RS15585	COG0582	viral genome integration into host DNA
PSNIH2_RS15610	COG3121	Chaperone
PSNIH2_RS15615	COG3539	Fimbrial protein
PSNIH2_RS15620	COG3710	Transcriptional regulator
PSNIH2_RS15625	COG2733	membrane
PSNIH2_RS15640	COG0795	lipopolysaccharide-transporting ATPase activity
PSNIH2_RS15645	COG0795	lipopolysaccharide-transporting ATPase activity
PSNIH2_RS15650	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PSNIH2_RS15655	COG2927	DNA polymerase III (CHI subunit)
PSNIH2_RS15685	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
PSNIH2_RS15695	COG0540	Belongs to the ATCase OTCase family
PSNIH2_RS15700	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
PSNIH2_RS15710	COG3525	Glycosyl hydrolase, family 20, catalytic domain
PSNIH2_RS15715	COG0366	Alpha amylase catalytic
PSNIH2_RS15720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PSNIH2_RS15725	COG1486	melibiose metabolic process
PSNIH2_RS15730	COG1447	Phosphotransferase system cellobiose-specific component IIA
PSNIH2_RS15750	COG0602	queuosine metabolic process
PSNIH2_RS15755	COG0702	epimerase
PSNIH2_RS15760	COG0693	protein deglycase activity
PSNIH2_RS15770	COG2827	Endonuclease containing a URI domain
PSNIH2_RS15775	COG3153	acetyltransferase
PSNIH2_RS15780	COG3154	lipid carrier protein
PSNIH2_RS15785	COG0826	peptidase U32
PSNIH2_RS15790	COG0826	peptidase U32
PSNIH2_RS15800	COG0513	Belongs to the DEAD box helicase family
PSNIH2_RS15815	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PSNIH2_RS15820	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PSNIH2_RS15825	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PSNIH2_RS15835	COG0195	Participates in both transcription termination and antitermination
PSNIH2_RS15855	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PSNIH2_RS15860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PSNIH2_RS15865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PSNIH2_RS15875	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PSNIH2_RS15880	COG1534	Rna-binding protein
PSNIH2_RS15890	COG2027	D-alanyl-D-alanine carboxypeptidase
PSNIH2_RS15895	COG0745	RESPONSE REGULATOR receiver
PSNIH2_RS15900	COG0642	Histidine kinase
PSNIH2_RS15905	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PSNIH2_RS15910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PSNIH2_RS15915	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PSNIH2_RS15920	COG0142	geranyltranstransferase activity
PSNIH2_RS15925	COG3423	Transcriptional regulator
PSNIH2_RS15930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PSNIH2_RS15935	COG5007	Belongs to the BolA IbaG family
PSNIH2_RS15940	COG3113	response to antibiotic
PSNIH2_RS15945	COG2854	intermembrane phospholipid transfer
PSNIH2_RS15950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PSNIH2_RS15955	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PSNIH2_RS15960	COG1127	ABC transporter
PSNIH2_RS15965	COG0530	calcium, potassium:sodium antiporter activity
PSNIH2_RS15975	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PSNIH2_RS15980	COG3117	lipopolysaccharide transmembrane transporter activity
PSNIH2_RS15985	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PSNIH2_RS15990	COG1137	ATPase activity
PSNIH2_RS15995	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PSNIH2_RS16010	COG1660	Displays ATPase and GTPase activities
PSNIH2_RS16015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PSNIH2_RS16025	COG2198	Histidine kinase
PSNIH2_RS16025	COG5002	protein histidine kinase activity
PSNIH2_RS16025	COG0784	Response regulator, receiver
PSNIH2_RS16030	COG0067	glutamate synthase
PSNIH2_RS16030	COG0069	glutamate synthase activity
PSNIH2_RS16030	COG0070	glutamate synthase
PSNIH2_RS16035	COG0493	'glutamate synthase
PSNIH2_RS16040	COG2969	positive regulation of protein catabolic process
PSNIH2_RS16045	COG0625	glutathione transferase activity
PSNIH2_RS16050	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PSNIH2_RS16055	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PSNIH2_RS16060	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PSNIH2_RS16065	COG3105	Protein conserved in bacteria
PSNIH2_RS16070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSNIH2_RS16075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSNIH2_RS16085	COG1438	arginine binding
PSNIH2_RS16105	COG2732	(Barnase) inhibitor
PSNIH2_RS16115	COG1289	transmembrane transporter activity
PSNIH2_RS16120	COG1566	PFAM secretion protein HlyD family protein
PSNIH2_RS16130	COG0583	DNA-binding transcription factor activity
PSNIH2_RS16135	COG0312	modulator of DNA gyrase
PSNIH2_RS16140	COG3164	Protein of unknown function
PSNIH2_RS16145	COG1530	ribonuclease E activity
PSNIH2_RS16155	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PSNIH2_RS16160	COG1792	Involved in formation and maintenance of cell shape
PSNIH2_RS16165	COG1077	Cell shape determining protein MreB Mrl
PSNIH2_RS16170	COG2200	EAL domain
PSNIH2_RS16170	COG2199	diguanylate cyclase activity
PSNIH2_RS16175	COG0604	alcohol dehydrogenase
PSNIH2_RS16180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PSNIH2_RS16185	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PSNIH2_RS16190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PSNIH2_RS16195	COG0511	ligase activity, forming carbon-carbon bonds
PSNIH2_RS16200	COG0439	Biotin carboxylase
PSNIH2_RS16205	COG3924	membrane
PSNIH2_RS16210	COG4145	pantothenate transmembrane transporter activity
PSNIH2_RS16215	COG2264	protein methyltransferase activity
PSNIH2_RS16235	COG1560	Kdo2-lipid A biosynthetic process
PSNIH2_RS16240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSNIH2_RS16245	COG4597	amino acid ABC transporter
PSNIH2_RS16250	COG0765	amino acid transport
PSNIH2_RS16255	COG1126	abc transporter atp-binding protein
PSNIH2_RS16295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PSNIH2_RS16300	COG1739	Uncharacterized protein family UPF0029
PSNIH2_RS16305	COG0006	proline dipeptidase activity
PSNIH2_RS16310	COG1250	3-hydroxyacyl-CoA dehydrogenase
PSNIH2_RS16310	COG1024	Enoyl-CoA hydratase
PSNIH2_RS16335	COG0084	hydrolase, TatD family'
PSNIH2_RS16340	COG0805	protein transport
PSNIH2_RS16355	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PSNIH2_RS16365	COG2226	methyltransferase
PSNIH2_RS16370	COG1322	Protein conserved in bacteria
PSNIH2_RS16380	COG0412	Dienelactone hydrolase
PSNIH2_RS16385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PSNIH2_RS16390	COG0583	DNA-binding transcription factor activity
PSNIH2_RS16400	COG0697	spore germination
PSNIH2_RS16405	COG2271	Major facilitator Superfamily
PSNIH2_RS16410	COG0584	glycerophosphoryl diester phosphodiesterase
PSNIH2_RS16415	COG0561	phosphatase activity
PSNIH2_RS16420	COG2267	carboxylic ester hydrolase activity
PSNIH2_RS16425	COG1280	lysine exporter protein (LysE YggA)
PSNIH2_RS16430	COG1280	lysine exporter protein (LysE YggA)
PSNIH2_RS16440	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
PSNIH2_RS16445	COG2050	protein possibly involved in aromatic compounds catabolism
PSNIH2_RS16450	COG2962	Rard protein
PSNIH2_RS16455	COG3180	Ammonia monooxygenase
PSNIH2_RS16470	COG0210	DNA helicase
PSNIH2_RS16475	COG1011	Hydrolase
PSNIH2_RS16485	COG3159	Protein conserved in bacteria
PSNIH2_RS16490	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PSNIH2_RS16525	COG0181	hydroxymethylbilane synthase activity
PSNIH2_RS16535	COG2959	enzyme of heme biosynthesis
PSNIH2_RS16540	COG3071	HemY protein
PSNIH2_RS16570	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PSNIH2_RS16580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PSNIH2_RS16585	COG2244	polysaccharide biosynthetic process
PSNIH2_RS16590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PSNIH2_RS16595	COG0456	acetyltransferase
PSNIH2_RS16600	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PSNIH2_RS16605	COG1088	dTDP-glucose 4,6-dehydratase activity
PSNIH2_RS16610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PSNIH2_RS16615	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PSNIH2_RS16620	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
PSNIH2_RS16625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PSNIH2_RS16630	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PSNIH2_RS16635	COG3118	belongs to the thioredoxin family
PSNIH2_RS16645	COG0248	Ppx GppA phosphatase
PSNIH2_RS16660	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PSNIH2_RS16665	COG0583	DNA-binding transcription factor activity
PSNIH2_RS16675	COG0129	dihydroxy-acid dehydratase activity
PSNIH2_RS16680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PSNIH2_RS16685	COG3978	acetolactate synthase activity
PSNIH2_RS16700	COG3085	chromosome segregation
PSNIH2_RS16705	COG0583	DNA-binding transcription factor activity
PSNIH2_RS16765	COG1309	transcriptional regulator
PSNIH2_RS16770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PSNIH2_RS16780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PSNIH2_RS16780	COG0678	peroxiredoxin activity
PSNIH2_RS16790	COG0137	argininosuccinate synthase activity
PSNIH2_RS16800	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PSNIH2_RS16805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PSNIH2_RS16810	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PSNIH2_RS16825	COG0460	homoserine dehydrogenase
PSNIH2_RS16825	COG0527	aspartate kinase activity
PSNIH2_RS16830	COG0626	cystathionine gamma-synthase activity
PSNIH2_RS16835	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
PSNIH2_RS16845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PSNIH2_RS16850	COG1609	Transcriptional regulator
PSNIH2_RS16855	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PSNIH2_RS16860	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PSNIH2_RS16870	COG1575	Belongs to the MenA family. Type 1 subfamily
PSNIH2_RS16875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PSNIH2_RS16880	COG3074	FtsZ-dependent cytokinesis
PSNIH2_RS16885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PSNIH2_RS16895	COG1494	fructose-1,6-bisphosphatase
PSNIH2_RS16900	COG2814	Major facilitator Superfamily
PSNIH2_RS16910	COG3152	Membrane
PSNIH2_RS16920	COG0149	triose-phosphate isomerase activity
PSNIH2_RS16930	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PSNIH2_RS16935	COG0205	6-phosphofructokinase activity
PSNIH2_RS16945	COG3678	ATP-independent chaperone mediated protein folding
PSNIH2_RS16950	COG0745	RESPONSE REGULATOR receiver
PSNIH2_RS16955	COG2205	protein histidine kinase activity
PSNIH2_RS16960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PSNIH2_RS16975	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PSNIH2_RS16980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PSNIH2_RS16985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PSNIH2_RS16990	COG4942	peptidase
PSNIH2_RS16995	COG2861	carbohydrate metabolic process
PSNIH2_RS17000	COG0438	transferase activity, transferring glycosyl groups
PSNIH2_RS17020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSNIH2_RS17030	COG0859	PFAM glycosyl transferase family 9
PSNIH2_RS17050	COG0438	transferase activity, transferring glycosyl groups
PSNIH2_RS17060	COG1216	Glycosyl transferase, family 2
PSNIH2_RS17065	COG0859	PFAM glycosyl transferase family 9
PSNIH2_RS17075	COG1519	Transferase
PSNIH2_RS17090	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PSNIH2_RS17095	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PSNIH2_RS17105	COG2003	Belongs to the UPF0758 family
PSNIH2_RS17110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PSNIH2_RS17130	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PSNIH2_RS17140	COG1131	(ABC) transporter
PSNIH2_RS17150	COG1561	YicC-like family, N-terminal region
PSNIH2_RS17165	COG2244	polysaccharide biosynthetic process
PSNIH2_RS17170	COG2860	membrane
PSNIH2_RS17180	COG0194	GDP metabolic process
PSNIH2_RS17185	COG1758	RNA polymerase activity
PSNIH2_RS17190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PSNIH2_RS17195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PSNIH2_RS17200	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PSNIH2_RS17205	COG2233	PERMEase
PSNIH2_RS17210	COG2982	Protein involved in outer membrane biogenesis
PSNIH2_RS17215	COG0456	acetyltransferase
PSNIH2_RS17220	COG1490	D-aminoacyl-tRNA deacylase activity
PSNIH2_RS17230	COG1011	Hydrolase
PSNIH2_RS17245	COG3852	Histidine kinase
PSNIH2_RS17250	COG2204	response regulator
PSNIH2_RS17255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PSNIH2_RS17260	COG3078	GTPase activator activity
PSNIH2_RS17270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PSNIH2_RS17270	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PSNIH2_RS17275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PSNIH2_RS17280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PSNIH2_RS17285	COG3084	Protein conserved in bacteria
PSNIH2_RS17295	COG1763	Mo-molybdopterin cofactor biosynthetic process
PSNIH2_RS17320	COG0477	Major facilitator Superfamily
PSNIH2_RS17325	COG1609	Transcriptional regulator
PSNIH2_RS17330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PSNIH2_RS17335	COG1879	ABC-type sugar transport system periplasmic component
PSNIH2_RS17340	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSNIH2_RS17345	COG1129	ABC transporter
PSNIH2_RS17375	COG3111	PFAM Bacterial OB fold (BOF) protein
PSNIH2_RS17380	COG0745	RESPONSE REGULATOR receiver
PSNIH2_RS17385	COG0642	Histidine kinase
PSNIH2_RS17400	COG2425	protein containing a von Willebrand factor type A (vWA) domain
PSNIH2_RS17405	COG1522	sequence-specific DNA binding
PSNIH2_RS17410	COG0716	FMN binding
PSNIH2_RS17425	COG3312	ion transport
PSNIH2_RS17430	COG0356	it plays a direct role in the translocation of protons across the membrane
PSNIH2_RS17440	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PSNIH2_RS17460	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PSNIH2_RS17470	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PSNIH2_RS17485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PSNIH2_RS17490	COG0573	inorganic phosphate transmembrane transporter activity
PSNIH2_RS17495	COG0581	inorganic phosphate transmembrane transporter activity
PSNIH2_RS17500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PSNIH2_RS17505	COG0704	Plays a role in the regulation of phosphate uptake
PSNIH2_RS17510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PSNIH2_RS17515	COG2252	PERMEase
PSNIH2_RS17530	COG1538	Outer membrane efflux protein
PSNIH2_RS17560	COG3121	Chaperone
PSNIH2_RS17585	COG0706	membrane insertase activity
PSNIH2_RS17600	COG0592	DNA-directed DNA polymerase activity
PSNIH2_RS17605	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PSNIH2_RS17610	COG0187	DNA topoisomerase II activity
PSNIH2_RS17615	COG3753	Protein conserved in bacteria
PSNIH2_RS17620	COG0561	phosphatase activity
PSNIH2_RS17625	COG0823	Involved in the tonB-independent uptake of proteins
PSNIH2_RS17630	COG5645	(Lipo)protein
PSNIH2_RS17645	COG3977	Valine--pyruvate aminotransferase
PSNIH2_RS17670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PSNIH2_RS17680	COG1609	Transcriptional regulator
PSNIH2_RS17685	COG2885	chlorophyll binding
PSNIH2_RS17690	COG2818	Glycosylase
PSNIH2_RS17705	COG1484	DNA-dependent DNA replication
PSNIH2_RS17715	COG3781	membrane
PSNIH2_RS17730	COG2186	Transcriptional regulator
PSNIH2_RS17755	COG1815	bacterial-type flagellum-dependent cell motility
PSNIH2_RS17760	COG1558	bacterial-type flagellum-dependent cell motility
PSNIH2_RS17775	COG4787	bacterial-type flagellum-dependent cell motility
PSNIH2_RS17805	COG1609	Transcriptional regulator
PSNIH2_RS17805	COG2207	Transcriptional regulator
PSNIH2_RS17810	COG4214	carbohydrate transport
PSNIH2_RS17820	COG4213	ABC transporter substrate-binding protein
PSNIH2_RS17830	COG1070	Carbohydrate kinase
PSNIH2_RS17835	COG3274	enterobacterial common antigen metabolic process
PSNIH2_RS17845	COG0751	glycine-tRNA ligase activity
PSNIH2_RS17850	COG0625	glutathione transferase activity
PSNIH2_RS17860	COG2864	formate dehydrogenase
PSNIH2_RS17865	COG0437	4 iron, 4 sulfur cluster binding
PSNIH2_RS17870	COG0243	molybdopterin cofactor binding
PSNIH2_RS17870	COG3383	formate dehydrogenase (NAD+) activity
PSNIH2_RS17880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PSNIH2_RS17885	COG2990	Protein conserved in bacteria
PSNIH2_RS17895	COG3722	fumarate hydratase activity
PSNIH2_RS17905	COG2213	PTS system mannitol-specific
PSNIH2_RS17905	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PSNIH2_RS17915	COG2944	sequence-specific DNA binding
PSNIH2_RS17930	COG1846	Transcriptional regulator
PSNIH2_RS17935	COG1764	response to oxidative stress
PSNIH2_RS17940	COG2194	sulfuric ester hydrolase activity
PSNIH2_RS17950	COG0747	negative chemotaxis
PSNIH2_RS17955	COG0601	transmembrane transport
PSNIH2_RS17960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSNIH2_RS17965	COG0444	Belongs to the ABC transporter superfamily
PSNIH2_RS17970	COG4608	Belongs to the ABC transporter superfamily
PSNIH2_RS17975	COG2194	sulfuric ester hydrolase activity
PSNIH2_RS17995	COG1192	Involved in chromosome partitioning
PSNIH2_RS18000	COG1215	transferase activity, transferring glycosyl groups
PSNIH2_RS18010	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
PSNIH2_RS18015	COG0457	Tetratricopeptide repeat
PSNIH2_RS18015	COG3118	belongs to the thioredoxin family
PSNIH2_RS18020	COG2199	diguanylate cyclase activity
PSNIH2_RS18020	COG2200	EAL domain
PSNIH2_RS18030	COG0612	Peptidase, M16
PSNIH2_RS18040	COG0625	glutathione transferase activity
PSNIH2_RS18045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PSNIH2_RS18050	COG2200	EAL domain
PSNIH2_RS18055	COG2982	Protein involved in outer membrane biogenesis
PSNIH2_RS18085	COG0477	Major facilitator Superfamily
PSNIH2_RS18090	COG1295	ribonuclease BN
PSNIH2_RS18095	COG0583	DNA-binding transcription factor activity
PSNIH2_RS18100	COG1028	Short-chain dehydrogenase reductase Sdr
PSNIH2_RS18105	COG0384	phenazine biosynthesis protein PhzF
PSNIH2_RS18110	COG0625	glutathione transferase activity
PSNIH2_RS18115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSNIH2_RS18125	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PSNIH2_RS18155	COG0596	Alpha beta hydrolase
PSNIH2_RS18165	COG3685	Protein conserved in bacteria
PSNIH2_RS18170	COG3729	General stress protein
PSNIH2_RS18185	COG1263	PTS System
PSNIH2_RS18185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PSNIH2_RS18195	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PSNIH2_RS18205	COG0400	carboxylic ester hydrolase activity
PSNIH2_RS18210	COG1132	(ABC) transporter
PSNIH2_RS18250	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PSNIH2_RS18255	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PSNIH2_RS18260	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PSNIH2_RS18265	COG2205	protein histidine kinase activity
PSNIH2_RS18270	COG2862	Uncharacterized protein family, UPF0114
PSNIH2_RS18300	COG1064	alcohol dehydrogenase
PSNIH2_RS18305	COG3387	PFAM Glycoside hydrolase 15-related
PSNIH2_RS18315	COG3188	usher protein
PSNIH2_RS18320	COG3121	Chaperone
PSNIH2_RS18325	COG3539	Fimbrial protein
PSNIH2_RS18345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PSNIH2_RS18350	COG1690	Belongs to the RtcB family
PSNIH2_RS18360	COG1234	tRNA 3'-trailer cleavage
PSNIH2_RS18380	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PSNIH2_RS18390	COG0339	signal peptide processing
PSNIH2_RS18395	COG0742	ribosomal rna small subunit methyltransferase
PSNIH2_RS18410	COG0306	phosphate transporter
PSNIH2_RS18415	COG2081	HI0933 family
PSNIH2_RS18435	COG1063	alcohol dehydrogenase
PSNIH2_RS18440	COG1546	Belongs to the CinA family
PSNIH2_RS18445	COG3468	outer membrane autotransporter barrel domain protein
PSNIH2_RS18450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSNIH2_RS18485	COG3706	GGDEF domain
PSNIH2_RS18490	COG0113	porphobilinogen synthase activity
PSNIH2_RS18495	COG0071	Belongs to the small heat shock protein (HSP20) family
PSNIH2_RS18520	COG2186	Transcriptional regulator
PSNIH2_RS18525	COG0628	permease
PSNIH2_RS18545	COG3718	enzyme involved in inositol metabolism
PSNIH2_RS18555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PSNIH2_RS18560	COG3962	Belongs to the TPP enzyme family
PSNIH2_RS18565	COG0673	inositol 2-dehydrogenase activity
PSNIH2_RS18570	COG1082	Xylose isomerase domain protein TIM barrel
PSNIH2_RS18575	COG1082	Xylose isomerase domain protein TIM barrel
PSNIH2_RS18585	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PSNIH2_RS18590	COG0425	Belongs to the sulfur carrier protein TusA family
PSNIH2_RS18595	COG3714	YhhN family
PSNIH2_RS18605	COG3776	membrane
PSNIH2_RS18610	COG0742	ribosomal rna small subunit methyltransferase
PSNIH2_RS18615	COG0552	protein localization to endoplasmic reticulum
PSNIH2_RS18615	COG0552	protein localization to endoplasmic reticulum
PSNIH2_RS18620	COG2884	Cell division ATP-binding protein ftsE
PSNIH2_RS18625	COG2177	Part of the ABC transporter FtsEX involved in
PSNIH2_RS18630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PSNIH2_RS18640	COG0683	leucine binding
PSNIH2_RS18650	COG4177	L-phenylalanine transmembrane transporter activity
PSNIH2_RS18685	COG0584	glycerophosphoryl diester phosphodiesterase
PSNIH2_RS18695	COG0405	Gamma-glutamyltransferase
PSNIH2_RS18700	COG1247	-acetyltransferase
PSNIH2_RS18710	COG1741	Belongs to the pirin family
PSNIH2_RS18715	COG1609	Transcriptional regulator
PSNIH2_RS18720	COG3265	gluconokinase activity
PSNIH2_RS18725	COG2610	gluconate transmembrane transporter activity
PSNIH2_RS18730	COG2095	MarC family integral membrane protein
PSNIH2_RS18735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PSNIH2_RS18745	COG1523	belongs to the glycosyl hydrolase 13 family
PSNIH2_RS18755	COG0297	glycogen (starch) synthase activity
PSNIH2_RS18760	COG0058	SHG alpha-glucan phosphorylase activity
PSNIH2_RS18765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PSNIH2_RS18780	COG1349	DNA-binding transcription factor activity
PSNIH2_RS18785	COG2909	trisaccharide binding
PSNIH2_RS18790	COG0058	SHG alpha-glucan phosphorylase activity
PSNIH2_RS18795	COG1640	4-alpha-glucanotransferase
PSNIH2_RS18800	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PSNIH2_RS18800	COG0316	Belongs to the HesB IscA family
PSNIH2_RS18805	COG1040	competence protein
PSNIH2_RS18820	COG0366	Alpha amylase catalytic
PSNIH2_RS18830	COG1918	ferrous iron import across plasma membrane
PSNIH2_RS18835	COG2183	response to ionizing radiation
PSNIH2_RS18840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PSNIH2_RS18855	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PSNIH2_RS18860	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PSNIH2_RS18865	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PSNIH2_RS18870	COG1011	Hydrolase
PSNIH2_RS18880	COG0494	nUDIX hydrolase
PSNIH2_RS18885	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PSNIH2_RS18910	COG4796	Type ii and iii secretion system protein
PSNIH2_RS18915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PSNIH2_RS18920	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PSNIH2_RS18935	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PSNIH2_RS18940	COG0546	phosphoglycolate phosphatase activity
PSNIH2_RS18945	COG0180	Tryptophanyl-tRNA synthetase
PSNIH2_RS18960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSNIH2_RS18965	COG0402	S-adenosylhomocysteine deaminase activity
PSNIH2_RS18970	COG0738	Major facilitator superfamily
PSNIH2_RS18980	COG2184	nucleotidyltransferase activity
PSNIH2_RS18990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PSNIH2_RS18995	COG1289	transmembrane transporter activity
PSNIH2_RS19000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PSNIH2_RS19005	COG1765	OsmC-like protein
PSNIH2_RS19010	COG3954	Phosphoribulokinase
PSNIH2_RS19015	COG3089	Belongs to the UPF0270 family
PSNIH2_RS19020	COG0429	hydrolase of the alpha beta-hydrolase fold
PSNIH2_RS19030	COG1609	Transcriptional regulator
PSNIH2_RS19035	COG4521	taurine ABC transporter
PSNIH2_RS19040	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PSNIH2_RS19045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSNIH2_RS19050	COG2175	clavaminate synthase activity
PSNIH2_RS19055	COG2199	diguanylate cyclase activity
PSNIH2_RS19055	COG2200	EAL domain
PSNIH2_RS19060	COG0488	(ABC) transporter
PSNIH2_RS19065	COG2249	NAD(P)H dehydrogenase (quinone) activity
PSNIH2_RS19070	COG0475	glutathione-regulated potassium exporter activity
PSNIH2_RS19070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PSNIH2_RS19075	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
PSNIH2_RS19080	COG1047	Peptidyl-prolyl cis-trans
PSNIH2_RS19085	COG2900	Belongs to the SlyX family
PSNIH2_RS19090	COG0545	Peptidyl-prolyl cis-trans isomerase
PSNIH2_RS19095	COG2964	Protein conserved in bacteria
PSNIH2_RS19105	COG2923	Belongs to the DsrF TusC family
PSNIH2_RS19110	COG2168	tRNA wobble position uridine thiolation
PSNIH2_RS19120	COG0049	tRNA binding
PSNIH2_RS19140	COG2193	ferroxidase activity
PSNIH2_RS19150	COG0051	transcription antitermination factor activity, RNA binding
PSNIH2_RS19160	COG0088	Forms part of the polypeptide exit tunnel
PSNIH2_RS19175	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PSNIH2_RS19190	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PSNIH2_RS19235	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PSNIH2_RS19245	COG1841	ribosomal large subunit assembly
PSNIH2_RS19250	COG0200	Binds to the 23S rRNA
PSNIH2_RS19255	COG0201	protein transport
PSNIH2_RS19265	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PSNIH2_RS19270	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PSNIH2_RS19280	COG0203	ribosomal protein L17
PSNIH2_RS19290	COG3036	rescue of stalled ribosome
PSNIH2_RS19295	COG1970	mechanosensitive ion channel activity
PSNIH2_RS19305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PSNIH2_RS19305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PSNIH2_RS19310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PSNIH2_RS19315	COG0242	peptide deformylase activity
PSNIH2_RS19320	COG0758	DNA mediated transformation
PSNIH2_RS19330	COG0009	L-threonylcarbamoyladenylate synthase
PSNIH2_RS19345	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PSNIH2_RS19370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PSNIH2_RS19415	COG0250	Participates in transcription elongation, termination and antitermination
PSNIH2_RS19430	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PSNIH2_RS19445	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PSNIH2_RS19460	COG2022	thiamine diphosphate biosynthetic process
PSNIH2_RS19470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PSNIH2_RS19480	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PSNIH2_RS19485	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
PSNIH2_RS19495	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PSNIH2_RS19505	COG3068	Protein conserved in bacteria
PSNIH2_RS19520	COG0151	Belongs to the GarS family
PSNIH2_RS19555	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
PSNIH2_RS19560	COG0646	methionine synthase
PSNIH2_RS19560	COG1410	methionine synthase
PSNIH2_RS19565	COG1283	sodium-dependent phosphate transmembrane transporter activity
PSNIH2_RS19580	COG0527	aspartate kinase activity
PSNIH2_RS19595	COG3223	Belongs to the PsiE family
PSNIH2_RS19605	COG1175	transmembrane transport
PSNIH2_RS19610	COG2182	Extracellular solute-binding protein
PSNIH2_RS19620	COG4580	involved in the transport of maltose and maltodextrins
PSNIH2_RS19630	COG3161	chorismate lyase activity
PSNIH2_RS19645	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PSNIH2_RS19655	COG0534	Mate efflux family protein
PSNIH2_RS19665	COG0735	belongs to the Fur family
PSNIH2_RS19680	COG1662	PFAM IS1 transposase
PSNIH2_RS19690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PSNIH2_RS19705	COG1522	sequence-specific DNA binding
PSNIH2_RS19715	COG1448	Aminotransferase
PSNIH2_RS19720	COG0432	Pfam Uncharacterised protein family UPF0047
PSNIH2_RS19725	COG2315	Protein conserved in bacteria
PSNIH2_RS19900	COG2252	PERMEase
PSNIH2_RS19935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PSNIH2_RS19955	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PSNIH2_RS20055	COG0306	phosphate transporter
PSNIH2_RS20250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PSNIH2_RS20425	COG3546	catalase activity
PSNIH2_RS20470	COG4993	Dehydrogenase
PSNIH2_RS20610	COG2205	protein histidine kinase activity
PSNIH2_RS20610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSNIH2_RS20715	COG3264	Mechanosensitive ion channel
PSNIH2_RS20715	COG1511	domain protein
PSNIH2_RS20750	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PSNIH2_RS20750	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PSNIH2_RS20875	COG3061	Opacity-associated protein A
PSNIH2_RS21545	COG0860	N-Acetylmuramoyl-L-alanine amidase
PSNIH2_RS21600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PSNIH2_RS21625	COG0557	exoribonuclease II activity
PSNIH2_RS21755	COG2911	Protein conserved in bacteria
PSNIH2_RS21970	COG1902	pentaerythritol trinitrate reductase activity
PSNIH2_RS21970	COG0446	pyridine nucleotide-disulphide oxidoreductase
PSNIH2_RS21990	COG2205	protein histidine kinase activity
PSNIH2_RS21990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSNIH2_RS22765	COG2375	cellular response to nickel ion
PSNIH2_RS22815	COG0741	lytic transglycosylase activity
PSNIH2_RS22965	COG0306	phosphate transporter
PSNIH2_RS23055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PSNIH2_RS23075	COG0306	phosphate transporter
PSNIH2_RS23185	COG2252	PERMEase
PSNIH2_RS23195	COG0025	NhaP-type Na H and K H
PSNIH2_RS23220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PSNIH2_RS23240	COG1301	dicarboxylic acid transport
PSNIH2_RS23410	COG2211	Major facilitator Superfamily
PSNIH2_RS23415	COG2211	Major facilitator Superfamily
PSNIH2_RS23430	COG2960	long-chain fatty acid transporting porin activity
PSNIH2_RS23440	COG3210	domain, Protein
PSNIH2_RS23450	COG3157	Type VI secretion system effector, Hcp
PSNIH2_RS23485	COG3209	COG3209 Rhs family protein
PSNIH2_RS23500	COG2197	response regulator
PSNIH2_RS23510	COG4774	siderophore transport
PSNIH2_RS23530	COG3710	Transcriptional regulator