locus-tag	class	description
HHO38_RS00010	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HHO38_RS00025	ENOG4105CNI	cell division protein FtsW
HHO38_RS00030	ENOG410647Z	gliding motility-associated lipoprotein GldH
HHO38_RS00035	ENOG4105MA4	psp1 domain protein
HHO38_RS00040	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HHO38_RS00045	ENOG4107TE5	Lipid kinase
HHO38_RS00050	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HHO38_RS00055	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HHO38_RS00065	ENOG4105CK5	oxidoreductase
HHO38_RS00085	ENOG41063TF	transcriptional regulator (AraC
HHO38_RS00100	ENOG4105C6N	Formate acetyltransferase
HHO38_RS00105	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HHO38_RS00110	ENOG4105DKQ	ROK family
HHO38_RS00130	ENOG4105VIE	preprotein translocase, subunit YajC
HHO38_RS00135	ENOG4107R6T	Involved in the transcription termination process (By similarity)
HHO38_RS00155	ENOG4105KNE	Phosphatidate cytidylyltransferase
HHO38_RS00160	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HHO38_RS00185	ENOG4108IUX	(ABC) transporter
HHO38_RS00190	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HHO38_RS00240	ENOG4105CMR	udp-glucose 4-epimerase
HHO38_RS00245	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HHO38_RS00260	ENOG4105Q84	sucrose synthase
HHO38_RS00265	ENOG4105K64	Glycosyl transferase, family 2
HHO38_RS00280	ENOG4105KPE	licD family
HHO38_RS00290	ENOG4105C5E	polysaccharide biosynthesis protein
HHO38_RS00300	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HHO38_RS00310	ENOG4105D3Q	Sugar transferase
HHO38_RS00325	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HHO38_RS00340	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HHO38_RS00345	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HHO38_RS00365	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HHO38_RS00385	ENOG4105D9N	nucleoside
HHO38_RS00395	ENOG4105BZU	Histidine kinase
HHO38_RS00400	ENOG4108K0D	peptidase, M48
HHO38_RS00410	ENOG4105DUM	transcriptional regulator, lysR family
HHO38_RS00415	ENOG4105HMI	Membrane
HHO38_RS00420	ENOG4108JQC	penicillin-binding protein 1A
HHO38_RS00425	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HHO38_RS00430	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HHO38_RS00435	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HHO38_RS00440	ENOG4108USZ	hydrogenase
HHO38_RS00450	ENOG4105DPX	Hydrogenase, large subunit
HHO38_RS00460	ENOG4105C45	hydrogenase expression formation protein (HypE)
HHO38_RS00465	ENOG4105CQS	hydrogenase expression formation protein HypD
HHO38_RS00475	ENOG4105C8H	hydrogenase maturation protein Hypf
HHO38_RS00480	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
HHO38_RS00485	ENOG4107RSS	Hydrogenase accessory protein HypB
HHO38_RS00520	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HHO38_RS00540	ENOG4105CGH	5'-nucleotidase
HHO38_RS00580	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HHO38_RS00600	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HHO38_RS00610	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HHO38_RS00615	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
HHO38_RS00620	ENOG4105DMW	Dehydrogenase reductase
HHO38_RS00635	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HHO38_RS00650	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HHO38_RS00660	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HHO38_RS00665	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS00685	ENOG4105DR4	Methyltransferase
HHO38_RS00700	ENOG4105CPC	Aldo Keto reductase
HHO38_RS00705	ENOG4105HEE	Binding Domain protein
HHO38_RS00710	ENOG4105CNU	cell division protein FtsK
HHO38_RS00720	ENOG4105C3M	thioredoxin reductase
HHO38_RS00735	ENOG4105F32	YngK protein
HHO38_RS00785	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HHO38_RS00790	ENOG4105HKU	nucleoside recognition domain-containing protein
HHO38_RS00795	ENOG4105C3R	Methionine synthase
HHO38_RS00805	ENOG4105TT1	Ragb susd domain-containing protein
HHO38_RS00820	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS00855	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HHO38_RS00865	ENOG4105CMR	udp-glucose 4-epimerase
HHO38_RS00870	ENOG4105D3Q	Sugar transferase
HHO38_RS00880	ENOG410650X	lipopolysaccharide core region biosynthetic process
HHO38_RS00900	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HHO38_RS00905	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HHO38_RS00910	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HHO38_RS00915	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HHO38_RS00955	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HHO38_RS00960	ENOG4105SCY	DNAK suppressor
HHO38_RS00965	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HHO38_RS00980	ENOG4108RWN	rrna methyltransferase
HHO38_RS01000	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HHO38_RS01010	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HHO38_RS01030	ENOG4105BZU	Histidine kinase
HHO38_RS01035	ENOG4107R73	Mate efflux family protein
HHO38_RS01045	ENOG4105C10	Electron transfer flavoprotein
HHO38_RS01050	ENOG4105BZJ	Electron transfer flavoprotein
HHO38_RS01065	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HHO38_RS01070	ENOG4105C5X	domain protein
HHO38_RS01075	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HHO38_RS01100	ENOG4108Z7F	N-acetyltransferase
HHO38_RS01110	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HHO38_RS01115	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HHO38_RS01120	ENOG41063SB	peptidase
HHO38_RS01125	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HHO38_RS01130	ENOG4105DZP	Membrane-associated zinc metalloprotease
HHO38_RS01140	ENOG4105DCF	alanine dehydrogenase
HHO38_RS01145	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HHO38_RS01175	ENOG4107T6X	nag kinase
HHO38_RS01195	ENOG4105DKW	ABC transporter
HHO38_RS01235	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS01250	ENOG4105D1H	recombination factor protein RarA
HHO38_RS01255	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HHO38_RS01260	ENOG4105C5I	Dehydrogenase
HHO38_RS01275	ENOG4105BZU	Histidine kinase
HHO38_RS01280	ENOG4105CMR	udp-glucose 4-epimerase
HHO38_RS01285	ENOG4105DGN	Electron transport complex
HHO38_RS01290	ENOG4105DZB	Electron transport complex
HHO38_RS01295	ENOG4108UQQ	Electron transport complex
HHO38_RS01300	ENOG4105D6A	Electron transport complex
HHO38_RS01305	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
HHO38_RS01310	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
HHO38_RS01325	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HHO38_RS01330	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHO38_RS01340	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HHO38_RS01345	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HHO38_RS01355	ENOG4105F7J	membrane-bound serine protease
HHO38_RS01360	ENOG4105I6B	RNA polymerase
HHO38_RS01365	ENOG4105CEY	Amp-dependent synthetase and ligase
HHO38_RS01370	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HHO38_RS01375	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HHO38_RS01390	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HHO38_RS01395	ENOG4105CEV	competence damage-inducible protein
HHO38_RS01410	ENOG4108HRK	Histidine kinase
HHO38_RS01415	ENOG4108NEV	two component transcriptional regulator, LytTR family
HHO38_RS01420	ENOG4107TT5	NLP P60 protein
HHO38_RS01425	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HHO38_RS01440	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HHO38_RS01445	ENOG4108INS	Transcriptional regulator
HHO38_RS01450	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HHO38_RS01455	ENOG4105DFA	alanine racemase domain protein
HHO38_RS01465	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS01480	ENOG4105D3Q	Sugar transferase
HHO38_RS01555	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HHO38_RS01570	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HHO38_RS01580	ENOG4108IJ1	Dehydrogenase
HHO38_RS01595	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HHO38_RS01635	ENOG4107S5I	aldo keto reductase
HHO38_RS01650	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HHO38_RS01655	ENOG4105C9K	Endothelin-converting enzyme 1
HHO38_RS01670	ENOG4106MPV	outer membrane protein SusE
HHO38_RS01680	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS01710	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HHO38_RS01720	ENOG4107QHE	Choloylglycine hydrolase
HHO38_RS01725	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HHO38_RS01735	ENOG4109015	Biopolymer transport protein exbD tolR
HHO38_RS01745	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HHO38_RS01755	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HHO38_RS01760	ENOG4108RJ9	Glycosyl transferase, family 2
HHO38_RS01775	ENOG4105BZU	Histidine kinase
HHO38_RS01785	ENOG4105EU0	Major facilitator Superfamily
HHO38_RS01795	ENOG4107KET	secretion protein, HlyD family
HHO38_RS01810	ENOG4105E8R	UPF0173 metal-dependent hydrolase
HHO38_RS01820	ENOG4105DCG	PHP domain protein
HHO38_RS01825	ENOG4105C5H	ABC transporter
HHO38_RS01885	ENOG4105VTW	prevent-host-death family
HHO38_RS01910	ENOG4105EMN	RNA polymerase sigma factor
HHO38_RS01975	ENOG4105VTR	Integrase
HHO38_RS01995	ENOG4105EUZ	Beta-lactamase domain protein
HHO38_RS02005	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HHO38_RS02030	ENOG4105CTQ	phosphohexokinase
HHO38_RS02060	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HHO38_RS02125	ENOG4105C2W	permease
HHO38_RS02130	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
HHO38_RS02135	ENOG4108TZA	Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity)
HHO38_RS02155	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HHO38_RS02160	ENOG4105CHR	reductase
HHO38_RS02165	ENOG4105DR9	pseudouridine synthase
HHO38_RS02185	ENOG4105CVG	Homoserine O-transsuccinylase
HHO38_RS02190	ENOG4105CFP	Peptidase U32
HHO38_RS02205	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HHO38_RS02230	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HHO38_RS02235	ENOG4105EIE	fructose-bisphosphate aldolase
HHO38_RS02240	ENOG4105KY8	Rubrerythrin
HHO38_RS02250	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HHO38_RS02260	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HHO38_RS02265	ENOG4105QNR	S1 RNA binding domain protein
HHO38_RS02280	ENOG4105KPE	licD family
HHO38_RS02285	ENOG4105W2C	Glycosyl transferase
HHO38_RS02290	ENOG4105CPK	Glycosyl transferase (Group 1
HHO38_RS02300	ENOG4105ER6	polysaccharide biosynthesis protein
HHO38_RS02305	ENOG4107QZB	decarboxylase
HHO38_RS02315	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HHO38_RS02330	ENOG4105CE1	Ferrous iron transport protein b
HHO38_RS02360	ENOG4105FJR	Lmbe family
HHO38_RS02375	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HHO38_RS02380	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HHO38_RS02385	ENOG4105E3Q	saccharopine dehydrogenase
HHO38_RS02390	ENOG4105BZU	Histidine kinase
HHO38_RS02405	ENOG4105IDI	abc transporter atp-binding protein
HHO38_RS02420	ENOG4105D05	Receptor
HHO38_RS02430	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HHO38_RS02435	ENOG4107RJ1	sodium solute
HHO38_RS02460	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HHO38_RS02470	ENOG4108MK9	spermidine N(1)-acetyltransferase
HHO38_RS02475	ENOG4108UJU	UPF0301 protein
HHO38_RS02495	ENOG4108UW5	maltose o-acetyltransferase
HHO38_RS02555	ENOG4105C9M	aspartyl-trna synthetase
HHO38_RS02560	ENOG4105EGD	dinuclear metal center protein, YbgI family
HHO38_RS02570	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HHO38_RS02575	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HHO38_RS02580	ENOG4105C1J	atp-dependent rna helicase
HHO38_RS02585	ENOG4105BZU	Histidine kinase
HHO38_RS02590	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HHO38_RS02640	ENOG4105CX6	glutaminyL-tRNA synthetase
HHO38_RS02645	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HHO38_RS02650	ENOG4105CUX	Signal transduction histidine kinase
HHO38_RS02660	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HHO38_RS02665	ENOG4107QI1	Mate efflux family protein
HHO38_RS02690	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
HHO38_RS02695	ENOG4105CHM	Aminotransferase
HHO38_RS02705	ENOG4105T16	Transcriptional regulator (AraC family)
HHO38_RS02720	ENOG4108Z66	YbaK ebsC protein
HHO38_RS02725	ENOG4105BZM	domain protein
HHO38_RS02730	ENOG4105BZU	Histidine kinase
HHO38_RS02735	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HHO38_RS02755	ENOG4105DZS	Phenylacetate-CoA ligase
HHO38_RS02760	ENOG4105BZU	Histidine kinase
HHO38_RS02765	ENOG4107S0N	DJ-1 family
HHO38_RS02775	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HHO38_RS02780	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HHO38_RS02785	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS02805	ENOG4105D3Q	Sugar transferase
HHO38_RS02815	ENOG4105PSV	Polysaccharide Biosynthesis Protein
HHO38_RS02835	ENOG4105KPE	licD family
HHO38_RS02840	ENOG4107SJB	teichoic acid biosynthesis
HHO38_RS02870	ENOG4105EJQ	L-serine dehydratase
HHO38_RS02875	ENOG4105DT9	hydrolase family 43
HHO38_RS02880	ENOG4105YA8	Transcriptional regulator
HHO38_RS02890	ENOG4105D0S	secretion protein (HlyD
HHO38_RS02895	ENOG4105CJ1	ABC, transporter
HHO38_RS02900	ENOG4105CJ1	ABC, transporter
HHO38_RS02905	ENOG4107QWP	ABC-2 type transporter
HHO38_RS02915	ENOG4105C6Z	Gluconate
HHO38_RS02955	ENOG4105DET	Rhamnulokinase
HHO38_RS02960	ENOG4105DKG	l-rhamnose isomerase
HHO38_RS02970	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
HHO38_RS03000	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HHO38_RS03025	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HHO38_RS03040	ENOG4107QQG	Dehydrogenase
HHO38_RS03065	ENOG4105C5Q	Transcriptional regulator
HHO38_RS03070	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HHO38_RS03075	ENOG4105CD3	dihydroorotase
HHO38_RS03080	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HHO38_RS03100	ENOG4105K64	Glycosyl transferase, family 2
HHO38_RS03110	ENOG4105K64	Glycosyl transferase, family 2
HHO38_RS03130	ENOG4107X35	defense response to bacterium
HHO38_RS03150	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HHO38_RS03155	ENOG4105CDU	Replicative dna helicase
HHO38_RS03175	ENOG4105K64	Glycosyl transferase, family 2
HHO38_RS03180	ENOG4108TJN	glycosyl transferase group 1
HHO38_RS03220	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HHO38_RS03225	ENOG4105E2D	ec 3.2.1.52
HHO38_RS03230	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HHO38_RS03240	ENOG4105C5H	ABC transporter
HHO38_RS03270	ENOG41067SE	Tetr family transcriptional regulator
HHO38_RS03335	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS03345	ENOG4108FN7	Aldo keto reductase
HHO38_RS03350	ENOG4105NF4	modulator of drug activity
HHO38_RS03410	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HHO38_RS03415	ENOG4105DVF	Cytosine-specific methyltransferase
HHO38_RS03490	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HHO38_RS03750	ENOG4108R86	Transcriptional regulator
HHO38_RS03760	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HHO38_RS03780	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS03830	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS03860	ENOG4105KVH	Transcriptional regulator
HHO38_RS03870	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HHO38_RS03875	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HHO38_RS03905	ENOG4105HFT	AraC family transcriptional regulator
HHO38_RS03925	ENOG4105D7N	magnesium and cobalt transport protein CorA
HHO38_RS03930	ENOG4105C98	muts2 protein
HHO38_RS03940	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHO38_RS03945	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HHO38_RS03950	ENOG4108WBT	adenosyltransferase
HHO38_RS03955	ENOG4108W76	histidinol phosphate phosphatase hisj family
HHO38_RS03960	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HHO38_RS03965	ENOG4105EXW	epimerase dehydratase
HHO38_RS03970	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HHO38_RS03975	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HHO38_RS03980	ENOG4105CDY	transcriptional regulatory protein
HHO38_RS04000	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HHO38_RS04010	ENOG4105D1Q	UPF0246 protein
HHO38_RS04025	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HHO38_RS04030	ENOG4105BZU	Histidine kinase
HHO38_RS04040	ENOG4105ER2	Ompa motb domain protein
HHO38_RS04125	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HHO38_RS04140	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HHO38_RS04145	ENOG4105DN9	Na H antiporter
HHO38_RS04150	ENOG4105DZW	Dipeptidase
HHO38_RS04160	ENOG4107YBY	Hydrolase
HHO38_RS04170	ENOG4105DZS	Phenylacetate-CoA ligase
HHO38_RS04200	ENOG4105CPC	Aldo Keto reductase
HHO38_RS04215	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
HHO38_RS04220	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
HHO38_RS04240	ENOG4105FB9	CRISPR-associated protein
HHO38_RS04250	ENOG4107QI1	Mate efflux family protein
HHO38_RS04255	ENOG4105DWY	Agmatine deiminase
HHO38_RS04265	ENOG4105CRQ	synthase (Component I)
HHO38_RS04285	ENOG4107SJI	Dehydrogenase
HHO38_RS04325	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HHO38_RS04330	ENOG4105C1J	atp-dependent rna helicase
HHO38_RS04355	ENOG41061MV	Arylsulfatase
HHO38_RS04360	ENOG4105EPC	oxidoreductase
HHO38_RS04365	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HHO38_RS04375	ENOG4105BZU	Histidine kinase
HHO38_RS04380	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HHO38_RS04395	ENOG4107R0I	Cell wall formation (By similarity)
HHO38_RS04400	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HHO38_RS04405	ENOG4107V1M	polysaccharide export protein
HHO38_RS04420	ENOG4105CSM	endonuclease III
HHO38_RS04425	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
HHO38_RS04445	ENOG4105DTQ	mandelate racemase muconate lactonizing
HHO38_RS04455	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HHO38_RS04460	ENOG4105E4F	Isochorismate synthase
HHO38_RS04470	ENOG410667J	hydrolase
HHO38_RS04485	ENOG4105CEM	UPF0597 protein
HHO38_RS04495	ENOG4107QUY	Guanine deaminase
HHO38_RS04510	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HHO38_RS04515	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HHO38_RS04520	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HHO38_RS04530	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HHO38_RS04570	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
HHO38_RS04575	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HHO38_RS04580	ENOG4105CGK	Exodeoxyribonuclease III
HHO38_RS04620	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
HHO38_RS04630	ENOG4108M15	ABC transporter
HHO38_RS04645	ENOG4107RAQ	aminopeptidase
HHO38_RS04655	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
HHO38_RS04670	ENOG4105DB7	PHP domain protein
HHO38_RS04685	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HHO38_RS04710	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
HHO38_RS04715	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HHO38_RS04720	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HHO38_RS04740	ENOG4105CUB	amino acid
HHO38_RS04760	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HHO38_RS04765	ENOG4108I0Z	Aconitate hydratase
HHO38_RS04775	ENOG4105D0C	transport protein
HHO38_RS04780	ENOG4107PPM	cobalt chelatase
HHO38_RS04795	ENOG4105E4R	Precorrin-3B C17-methyltransferase
HHO38_RS04805	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
HHO38_RS04810	ENOG4107UA7	cobalamin biosynthesis protein CbiD
HHO38_RS04830	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HHO38_RS04835	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HHO38_RS04845	ENOG4105C5I	Dehydrogenase
HHO38_RS04850	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HHO38_RS04855	ENOG4105BZU	Histidine kinase
HHO38_RS04860	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HHO38_RS04880	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HHO38_RS04885	ENOG4105K6T	rare lipoprotein A
HHO38_RS04890	ENOG4105CA0	peroxidase
HHO38_RS04895	ENOG4108V0P	LemA family
HHO38_RS04905	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
HHO38_RS04910	ENOG4107QHI	-hydrogenase
HHO38_RS04915	ENOG4107QIZ	NADH dehydrogenase
HHO38_RS04920	ENOG4105M1A	NADP-reducing hydrogenase, subunit B
HHO38_RS04925	ENOG4105D7W	serine acetyltransferase
HHO38_RS04970	ENOG4105BZU	Histidine kinase
HHO38_RS04975	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HHO38_RS04990	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HHO38_RS04995	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HHO38_RS05020	ENOG4105VMP	Transcriptional regulator
HHO38_RS05040	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HHO38_RS05135	ENOG4105E0A	ABC, transporter
HHO38_RS05140	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
HHO38_RS05150	ENOG4105DVK	Precorrin-2 c20-methyltransferase
HHO38_RS05160	ENOG4105CKU	formyltetrahydrofolate synthetase
HHO38_RS05165	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HHO38_RS05175	ENOG4105C7K	acetolactate synthase
HHO38_RS05195	ENOG4105CNT	hydrolase family 2
HHO38_RS05200	ENOG4105C87	Aminotransferase class I and II
HHO38_RS05210	ENOG4105ENX	hydrolase
HHO38_RS05215	ENOG4105FTV	AraC Family Transcriptional Regulator
HHO38_RS05220	ENOG4105EQD	regulatoR
HHO38_RS05245	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HHO38_RS05260	ENOG4105C6T	cysteine synthase
HHO38_RS05265	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HHO38_RS05270	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HHO38_RS05275	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HHO38_RS05280	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HHO38_RS05285	ENOG4105VTR	Integrase
HHO38_RS05315	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
HHO38_RS05350	ENOG4105CUY	Mechanosensitive ion channel
HHO38_RS05355	ENOG4105CUY	Mechanosensitive ion channel
HHO38_RS05360	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HHO38_RS05390	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
HHO38_RS05410	ENOG4107QVM	von Willebrand factor, type A
HHO38_RS05430	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HHO38_RS05440	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HHO38_RS05445	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HHO38_RS05450	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHO38_RS05470	ENOG4105C4R	Atp-dependent dna helicase
HHO38_RS05490	ENOG4105VFU	Rna-binding protein
HHO38_RS05495	ENOG4105DN3	alpha-2-macroglobulin domain protein
HHO38_RS05495	ENOG4105DN3	alpha-2-macroglobulin domain protein
HHO38_RS05530	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HHO38_RS05540	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HHO38_RS05550	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HHO38_RS05560	ENOG4105E5D	amino acid
HHO38_RS05575	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HHO38_RS05580	ENOG4105C4X	radical SAM domain protein
HHO38_RS05585	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HHO38_RS05595	ENOG4108UT2	hemolysin iii
HHO38_RS05605	ENOG4105C59	p-type ATPase
HHO38_RS05625	ENOG4105G6Z	alkaline phosphatase
HHO38_RS05630	ENOG4105CXT	aspartate transcarbamylase
HHO38_RS05635	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
HHO38_RS05655	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HHO38_RS05660	ENOG4105WMR	Protein CrcB homolog
HHO38_RS05665	ENOG4105K64	Glycosyl transferase, family 2
HHO38_RS05670	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HHO38_RS05700	ENOG4105E2K	Glycosyl transferase (Group 1
HHO38_RS05805	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HHO38_RS05825	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS05840	ENOG4105EKQ	RNA-directed DNA polymerase
HHO38_RS05850	ENOG4108R86	Transcriptional regulator
HHO38_RS05945	ENOG4105BZU	Histidine kinase
HHO38_RS06050	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HHO38_RS06150	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS06205	ENOG4105D3Q	Sugar transferase
HHO38_RS06220	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS06240	ENOG4107VJ3	V-type ATP synthase subunit I (EC 3.6.3.14)
HHO38_RS06250	ENOG4107RQX	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
HHO38_RS06255	ENOG4107RVI	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
HHO38_RS06285	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HHO38_RS06290	ENOG4105CVK	Glutamate decarboxylase
HHO38_RS06295	ENOG4105CSV	Glutaminase
HHO38_RS06320	ENOG4105DBI	uridine monophosphokinase
HHO38_RS06330	ENOG4106CKV	Pap2 superfamily protein
HHO38_RS06335	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HHO38_RS06355	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HHO38_RS06360	ENOG4105BZU	Histidine kinase
HHO38_RS06365	ENOG4105BZU	Histidine kinase
HHO38_RS06370	ENOG4105DY9	regulatoR
HHO38_RS06375	ENOG4108HRK	Histidine kinase
HHO38_RS06390	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HHO38_RS06400	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HHO38_RS06420	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HHO38_RS06425	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
HHO38_RS06440	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HHO38_RS06450	ENOG4105F1A	Pyruvate formate-lyase
HHO38_RS06455	ENOG4105C6N	Formate acetyltransferase
HHO38_RS06465	ENOG4107QNK	)-transporter
HHO38_RS06470	ENOG4105C93	Xylose Isomerase
HHO38_RS06475	ENOG4105CMG	Carbohydrate kinase
HHO38_RS06485	ENOG4105CZN	Potassium uptake protein
HHO38_RS06510	ENOG4108ZNS	ferredoxin-type protein NapF
HHO38_RS06515	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HHO38_RS06535	ENOG4108IAB	Phoh family
HHO38_RS06560	ENOG4105BZU	Histidine kinase
HHO38_RS06580	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HHO38_RS06590	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HHO38_RS06620	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HHO38_RS06630	ENOG4105C5Z	peptidase
HHO38_RS06635	ENOG4108Z8I	decarboxylase
HHO38_RS06640	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HHO38_RS06645	ENOG4105CCT	upf0313 protein
HHO38_RS06650	ENOG4105KME	endoribonuclease L-psp
HHO38_RS06655	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HHO38_RS06680	ENOG4108HRK	Histidine kinase
HHO38_RS06685	ENOG4108VAC	response regulator
HHO38_RS06695	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HHO38_RS06710	ENOG4108I6A	alcohol dehydrogenase
HHO38_RS06720	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HHO38_RS06730	ENOG41083ND	50S ribosomal protein L33
HHO38_RS06735	ENOG4105KDC	50s ribosomal protein l28
HHO38_RS06755	ENOG4105C7S	Dehydrogenase
HHO38_RS06760	ENOG4105CPP	Dehydrogenase, E1 component
HHO38_RS06765	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HHO38_RS06770	ENOG4105RV9	Transcriptional regulator
HHO38_RS06820	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
HHO38_RS06825	ENOG4105BZU	Histidine kinase
HHO38_RS06830	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HHO38_RS06835	ENOG4105BZA	Phosphoglycerate kinase
HHO38_RS06840	ENOG4108IUM	Glycogen debranching enzyme
HHO38_RS06845	ENOG4105CDU	Replicative dna helicase
HHO38_RS06860	ENOG4105CWX	Alpha-1,2-mannosidase
HHO38_RS06865	ENOG4105E2D	ec 3.2.1.52
HHO38_RS06880	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HHO38_RS06885	ENOG4105VJV	50s ribosomal protein L35
HHO38_RS06890	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HHO38_RS06895	ENOG4105C22	threonyL-tRNA synthetase
HHO38_RS06905	ENOG4108JIK	carboxylase
HHO38_RS06910	ENOG4105D8K	carboxyl transferase
HHO38_RS06915	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HHO38_RS06920	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HHO38_RS06925	ENOG4105D3Q	Sugar transferase
HHO38_RS06930	ENOG4105RWF	major outer membrane protein OmpA
HHO38_RS06935	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HHO38_RS06940	ENOG4105C30	Nad-dependent epimerase dehydratase
HHO38_RS06945	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HHO38_RS06955	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HHO38_RS06960	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HHO38_RS06965	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HHO38_RS06970	ENOG4107QN2	dihydrolipoyl dehydrogenase
HHO38_RS06990	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HHO38_RS07000	ENOG4105BZU	Histidine kinase
HHO38_RS07010	ENOG4105BZG	amino acid carrier protein
HHO38_RS07020	ENOG4105CKB	glycosidase
HHO38_RS07035	ENOG41061GT	Aldolase
HHO38_RS07045	ENOG4105CMT	Dihydroxyacetone kinase
HHO38_RS07085	ENOG4108RMU	ferritin dps family protein
HHO38_RS07095	ENOG4108RMU	ferritin dps family protein
HHO38_RS07105	ENOG4108JA2	transcriptioN-repair coupling factor
HHO38_RS07110	ENOG4105CEY	Amp-dependent synthetase and ligase
HHO38_RS07130	ENOG4105DFD	Na H antiporter
HHO38_RS07155	ENOG4105D05	Receptor
HHO38_RS07160	ENOG4105MRR	Transcriptional regulator (By similarity)
HHO38_RS07170	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS07180	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS07190	ENOG4105K78	MarR family Transcriptional regulator
HHO38_RS07195	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HHO38_RS07210	ENOG4108IJ0	Aspartate ammonia-lyase
HHO38_RS07215	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HHO38_RS07220	ENOG4105CRQ	synthase (Component I)
HHO38_RS07225	ENOG4105DDQ	anthranilate synthase
HHO38_RS07235	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HHO38_RS07240	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HHO38_RS07245	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HHO38_RS07250	ENOG4108I6A	alcohol dehydrogenase
HHO38_RS07255	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
HHO38_RS07260	ENOG4107QR9	Iron-sulfur cluster binding protein
HHO38_RS07265	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HHO38_RS07275	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HHO38_RS07280	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HHO38_RS07285	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HHO38_RS07305	ENOG4105CPK	Glycosyl transferase (Group 1
HHO38_RS07310	ENOG4105CG5	Glycosyl transferase (Group 1
HHO38_RS07385	ENOG4105D3Q	Sugar transferase
HHO38_RS07400	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS07405	ENOG4105DGW	oligopeptidase A
HHO38_RS07410	ENOG4105DGW	oligopeptidase A
HHO38_RS07420	ENOG4105EA8	2-Nitropropane dioxygenase
HHO38_RS07450	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
HHO38_RS07465	ENOG4105GTN	ParB Domain Protein Nuclease
HHO38_RS07470	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
HHO38_RS07500	ENOG4105BZU	Histidine kinase
HHO38_RS07505	ENOG4105CWX	Alpha-1,2-mannosidase
HHO38_RS07510	ENOG4105CWX	Alpha-1,2-mannosidase
HHO38_RS07565	ENOG4105CWX	Alpha-1,2-mannosidase
HHO38_RS07585	ENOG41063TF	transcriptional regulator (AraC
HHO38_RS07615	ENOG4105C19	ABC transporter
HHO38_RS07655	ENOG4107RUE	extracellular solute-binding protein family 1
HHO38_RS07660	ENOG4105D38	putrescine abc transporter
HHO38_RS07665	ENOG4105F38	ABC transporter, permease
HHO38_RS07670	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HHO38_RS07680	ENOG4105C9Q	fumarate hydratase class II
HHO38_RS07685	ENOG4105CKK	Glycosyl transferase, family 2
HHO38_RS07715	ENOG4108RVA	ribokinase
HHO38_RS07725	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS07735	ENOG4105KVH	Transcriptional regulator
HHO38_RS07755	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HHO38_RS07765	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HHO38_RS07780	ENOG4108YZG	isomerase
HHO38_RS07785	ENOG4107QSA	Oxaloacetate decarboxylase
HHO38_RS07810	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HHO38_RS07825	ENOG4105CBG	Sulfatase
HHO38_RS07830	ENOG41061MV	Arylsulfatase
HHO38_RS07835	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HHO38_RS07865	ENOG4108AEY	RNA polymerase sigma factor
HHO38_RS07900	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HHO38_RS07910	ENOG4107QKV	phosphomannomutase
HHO38_RS07920	ENOG4105SFS	phosphoesterase RecJ domain protein
HHO38_RS07925	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HHO38_RS07930	ENOG4105DJV	ribulose-phosphate 3-epimerase
HHO38_RS07980	ENOG4105Q2H	domain protein
HHO38_RS07985	ENOG4105HDK	L-asparaginase
HHO38_RS07990	ENOG4105EN6	Membrane
HHO38_RS08000	ENOG4105C5H	ABC transporter
HHO38_RS08010	ENOG4105K5M	30s ribosomal protein S16
HHO38_RS08020	ENOG4105NGQ	Thioredoxin
HHO38_RS08105	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HHO38_RS08110	ENOG4105DG6	mannose-6-phosphate isomerase
HHO38_RS08115	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HHO38_RS08125	ENOG4108DBC	nitroreductase
HHO38_RS08130	ENOG4105EYH	Exonuclease
HHO38_RS08135	ENOG4107RH8	nuclease SbcCD subunit D
HHO38_RS08150	ENOG4105C6K	Malic enzyme
HHO38_RS08155	ENOG4108JQ1	Dehydrogenase
HHO38_RS08180	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HHO38_RS08195	ENOG4105WD1	Membrane
HHO38_RS08200	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HHO38_RS08215	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HHO38_RS08220	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HHO38_RS08225	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HHO38_RS08235	ENOG4105DKQ	ROK family
HHO38_RS08240	ENOG4105D0C	transport protein
HHO38_RS08255	ENOG4105DT9	hydrolase family 43
HHO38_RS08260	ENOG4105DZ0	fad dependent oxidoreductase
HHO38_RS08265	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HHO38_RS08275	ENOG4105D44	asparaginase
HHO38_RS08280	ENOG4105CWX	Alpha-1,2-mannosidase
HHO38_RS08290	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HHO38_RS08295	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HHO38_RS08300	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HHO38_RS08325	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS08335	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS08340	ENOG4105IIU	Aminopeptidase
HHO38_RS08350	ENOG4108V2W	Carbonate dehydratase
HHO38_RS08360	ENOG4105CPC	Aldo Keto reductase
HHO38_RS08380	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HHO38_RS08385	ENOG4105SYT	Methylenetetrahydrofolate reductase
HHO38_RS08395	ENOG4105UQX	Mate efflux family protein
HHO38_RS08420	ENOG4108IJF	Heavy metal efflux pump, CzcA
HHO38_RS08470	ENOG4105CBG	Sulfatase
HHO38_RS08480	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HHO38_RS08485	ENOG4105C0H	protease
HHO38_RS08495	ENOG4107S2Z	UPF0761 membrane protein
HHO38_RS08500	ENOG4107QJQ	Mate efflux family protein
HHO38_RS08515	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HHO38_RS08520	ENOG4108R6K	riboflavin synthase, subunit alpha
HHO38_RS08585	ENOG4107XI7	Tetr family transcriptional regulator
HHO38_RS08595	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HHO38_RS08610	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HHO38_RS08615	ENOG4105CHR	reductase
HHO38_RS08620	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HHO38_RS08625	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HHO38_RS08630	ENOG4105VEJ	Heat shock protein
HHO38_RS08665	ENOG4105CAQ	asparagine synthetase
HHO38_RS08675	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HHO38_RS08680	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
HHO38_RS08700	ENOG4108DWA	Nad synthetase
HHO38_RS08720	ENOG4105EE0	oxidoreductase
HHO38_RS08730	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HHO38_RS08735	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HHO38_RS08745	ENOG4105K46	50S ribosomal protein l27
HHO38_RS08750	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HHO38_RS08785	ENOG4108P1X	synthase
HHO38_RS08800	ENOG4105KPE	licD family
HHO38_RS08815	ENOG4107QRS	glycosyltransferase group 2 family protein
HHO38_RS08830	ENOG4105ESV	Glycosyl transferase, family 4
HHO38_RS08855	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS08895	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HHO38_RS08920	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HHO38_RS08925	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HHO38_RS08945	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HHO38_RS08970	ENOG410624X	efflux transporter, rnd family, mfp subunit
HHO38_RS08980	ENOG4106N3A	copper homeostasis protein cutc
HHO38_RS08990	ENOG4105CFH	Aspartokinase
HHO38_RS08995	ENOG4105E3H	phosphoglycerate mutase
HHO38_RS09000	ENOG4105D98	threonine synthase
HHO38_RS09015	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HHO38_RS09065	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HHO38_RS09070	ENOG4105CD3	dihydroorotase
HHO38_RS09075	ENOG4105CE4	GlcNAc 6-P deacetylase
HHO38_RS09080	ENOG4105C5H	ABC transporter
HHO38_RS09085	ENOG4105F6J	Alpha beta hydrolase fold
HHO38_RS09105	ENOG4105CNT	hydrolase family 2
HHO38_RS09110	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HHO38_RS09160	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HHO38_RS09170	ENOG4105C59	p-type ATPase
HHO38_RS09185	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HHO38_RS09190	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HHO38_RS09195	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HHO38_RS09210	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HHO38_RS09220	ENOG4105DGW	oligopeptidase A
HHO38_RS09235	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HHO38_RS09245	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HHO38_RS09255	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HHO38_RS09300	ENOG4108JUA	Transcriptional regulator
HHO38_RS09315	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
HHO38_RS09325	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HHO38_RS09335	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HHO38_RS09340	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HHO38_RS09345	ENOG4105C37	(CBS) domain
HHO38_RS09365	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HHO38_RS09370	ENOG4107UNS	conserved inner membrane protein
HHO38_RS09385	ENOG4105CKK	Glycosyl transferase, family 2
HHO38_RS09395	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
HHO38_RS09400	ENOG4105C01	Dihydroxy-acid dehydratase
HHO38_RS09405	ENOG4105CJ2	(LipO)protein
HHO38_RS09415	ENOG4108Z03	MAF-like protein
HHO38_RS09430	ENOG4108DBC	nitroreductase
HHO38_RS09440	ENOG4108ZVT	methylmalonyl-coA epimerase
HHO38_RS09445	ENOG4107QX3	carboxylase
HHO38_RS09455	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
HHO38_RS09460	ENOG4105D9Q	decarboxylase (Beta subunit)
HHO38_RS09470	ENOG41072GX	Peptidase M22 Glycoprotease
HHO38_RS09475	ENOG4105DSJ	YicC domain protein
HHO38_RS09480	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HHO38_RS09490	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HHO38_RS09500	ENOG4105CRK	lysyL-tRNA synthetase
HHO38_RS09505	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HHO38_RS09510	ENOG4107QP8	phosphohexose isomerase
HHO38_RS09545	ENOG4107V40	secretion protein, HlyD family
HHO38_RS09625	ENOG4105DMT	epimerase dehydratase
HHO38_RS09640	ENOG4108IJ1	Dehydrogenase
HHO38_RS09650	ENOG4105CK5	oxidoreductase
HHO38_RS09660	ENOG4108UW5	maltose o-acetyltransferase
HHO38_RS09670	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HHO38_RS09685	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HHO38_RS09695	ENOG4105ER6	polysaccharide biosynthesis protein
HHO38_RS09740	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS09745	ENOG4105QNF	Outer membrane lipoprotein
HHO38_RS09750	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HHO38_RS09765	ENOG4105BZU	Histidine kinase
HHO38_RS09770	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HHO38_RS09785	ENOG4105CRE	cytochrome C
HHO38_RS09795	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
HHO38_RS09800	ENOG4108W6G	cytochrome C
HHO38_RS09805	ENOG4105ER2	Ompa motb domain protein
HHO38_RS09820	ENOG4105EDR	glucose galactose transporter
HHO38_RS09825	ENOG4105QJH	Domain of unknown function (DUF718)
HHO38_RS09835	ENOG4105VN1	Heat shock protein
HHO38_RS09855	ENOG4108HQS	Glycine betaine
HHO38_RS09865	ENOG4105BZU	Histidine kinase
HHO38_RS09870	ENOG4105D3R	alkyl hydroperoxide reductase
HHO38_RS09885	ENOG4105C2I	pirin domain protein
HHO38_RS09890	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HHO38_RS09900	ENOG4105FTV	AraC Family Transcriptional Regulator
HHO38_RS09950	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS10065	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HHO38_RS10165	ENOG4105BZU	Histidine kinase
HHO38_RS10180	ENOG4105EKQ	RNA-directed DNA polymerase
HHO38_RS10195	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS10215	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HHO38_RS10255	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS10260	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS10290	ENOG4105KT7	mgtC SapB transporter
HHO38_RS10295	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HHO38_RS10305	ENOG4105DN9	Na H antiporter
HHO38_RS10315	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HHO38_RS10330	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HHO38_RS10340	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HHO38_RS10350	ENOG4105CDH	Citrulline--aspartate ligase
HHO38_RS10355	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HHO38_RS10360	ENOG4105C8Y	Acetylornithine aminotransferase
HHO38_RS10390	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
HHO38_RS10395	ENOG4105HY2	Glycosidase related protein
HHO38_RS10400	ENOG4105CT4	transporter
HHO38_RS10405	ENOG4105DFY	n-acylglucosamine 2-epimerase
HHO38_RS10425	ENOG4105CEP	NADH dehydrogenase
HHO38_RS10440	ENOG4105CEY	Amp-dependent synthetase and ligase
HHO38_RS10445	ENOG4105E2D	ec 3.2.1.52
HHO38_RS10455	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HHO38_RS10465	ENOG4107QJZ	Glycosyl transferase, family 2
HHO38_RS10500	ENOG4105WEF	catalase
HHO38_RS10520	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HHO38_RS10545	ENOG4107S1W	4-alpha-glucanotransferase
HHO38_RS10555	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HHO38_RS10565	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HHO38_RS10570	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HHO38_RS10575	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HHO38_RS10580	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
HHO38_RS10585	ENOG41061MV	Arylsulfatase
HHO38_RS10590	ENOG41061MV	Arylsulfatase
HHO38_RS10610	ENOG4105DU6	RNA polymerase
HHO38_RS10620	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HHO38_RS10625	ENOG4105FE9	pseudouridine synthase
HHO38_RS10630	ENOG4108YZT	Adenosylcobinamide kinase
HHO38_RS10635	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HHO38_RS10640	ENOG4107ZET	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HHO38_RS10700	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HHO38_RS10705	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HHO38_RS10720	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS10765	ENOG4107QI1	Mate efflux family protein
HHO38_RS10775	ENOG4105BZU	Histidine kinase
HHO38_RS10815	ENOG4105J0Q	Transcriptional regulator
HHO38_RS10820	ENOG4105ECQ	AraC Family Transcriptional Regulator
HHO38_RS10890	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS11030	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS11290	ENOG4105FA0	parb-like partition protein
HHO38_RS11300	ENOG4107QJE	Chromosome Partitioning Protein
HHO38_RS11340	ENOG4105E4C	Lytic transglycosylase catalytic
HHO38_RS11400	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HHO38_RS11435	ENOG41067SE	Tetr family transcriptional regulator
HHO38_RS11455	ENOG4107QI1	Mate efflux family protein
HHO38_RS11560	ENOG4105BZU	Histidine kinase
HHO38_RS11665	ENOG4105BZU	Histidine kinase
HHO38_RS11725	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS11730	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS11765	ENOG4105EKQ	RNA-directed DNA polymerase
HHO38_RS11780	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS11800	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HHO38_RS11835	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS11845	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HHO38_RS11850	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HHO38_RS11895	ENOG41061MV	Arylsulfatase
HHO38_RS11900	ENOG4105CBG	Sulfatase
HHO38_RS11905	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HHO38_RS11910	ENOG4105C5F	glutamine synthetase
HHO38_RS11915	ENOG4107QI1	Mate efflux family protein
HHO38_RS11920	ENOG4105BZP	glycoside hydrolase 15-related
HHO38_RS11945	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HHO38_RS11950	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HHO38_RS11955	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HHO38_RS11965	ENOG4105C08	Histidine kinase
HHO38_RS11975	ENOG4105CFH	Aspartokinase
HHO38_RS11985	ENOG4105F5W	AtP-binding protein
HHO38_RS12090	ENOG4107XGZ	Hydrolase
HHO38_RS12105	ENOG4105E6M	Sulphatase-modifying factor protein
HHO38_RS12130	ENOG4107ZSV	Receptor
HHO38_RS12135	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HHO38_RS12140	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HHO38_RS12145	ENOG4105D3Q	Sugar transferase
HHO38_RS12155	ENOG4105CPK	Glycosyl transferase (Group 1
HHO38_RS12230	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS12245	ENOG4107R37	Glutamate dehydrogenase
HHO38_RS12250	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HHO38_RS12255	ENOG4108S0S	Nucleotidyl transferase
HHO38_RS12265	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HHO38_RS12275	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HHO38_RS12395	ENOG4108KU3	Integrase
HHO38_RS12435	ENOG4108NEV	two component transcriptional regulator, LytTR family
HHO38_RS12480	ENOG4105CWX	Alpha-1,2-mannosidase
HHO38_RS12505	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HHO38_RS12525	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HHO38_RS12565	ENOG4108NEV	two component transcriptional regulator, LytTR family
HHO38_RS12595	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HHO38_RS12600	ENOG4108ZT0	50S ribosomal protein l17
HHO38_RS12605	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HHO38_RS12610	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HHO38_RS12615	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HHO38_RS12620	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHO38_RS12625	ENOG410864M	50S ribosomal protein L36
HHO38_RS12630	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HHO38_RS12640	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HHO38_RS12645	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HHO38_RS12650	ENOG41084HK	50S ribosomal protein L30
HHO38_RS12655	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HHO38_RS12660	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HHO38_RS12665	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HHO38_RS12670	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HHO38_RS12675	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HHO38_RS12680	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHO38_RS12685	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HHO38_RS12690	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HHO38_RS12695	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HHO38_RS12700	ENOG41062E3	50S ribosomal protein L29
HHO38_RS12705	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HHO38_RS12710	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HHO38_RS12715	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HHO38_RS12720	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HHO38_RS12725	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHO38_RS12730	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HHO38_RS12735	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HHO38_RS12740	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HHO38_RS12745	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HHO38_RS12750	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HHO38_RS12755	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HHO38_RS12760	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HHO38_RS12775	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HHO38_RS12800	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HHO38_RS12805	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HHO38_RS12810	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HHO38_RS12815	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HHO38_RS12820	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HHO38_RS12825	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HHO38_RS12835	ENOG4108IUZ	ABC transporter
HHO38_RS12850	ENOG4105DHJ	ABC, transporter
HHO38_RS12855	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HHO38_RS12865	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HHO38_RS12870	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HHO38_RS12875	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HHO38_RS12880	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HHO38_RS12890	ENOG4107RJ9	Cell division protein FtsX
HHO38_RS12935	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HHO38_RS12945	ENOG4105CYC	Transferase
HHO38_RS12950	ENOG4105C8U	phosphate abc transporter
HHO38_RS12955	ENOG4105E2Z	phosphate ABC transporter (Permease
HHO38_RS12960	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HHO38_RS12990	ENOG4105BZ1	(ABC) transporter
HHO38_RS13005	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
HHO38_RS13060	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HHO38_RS13065	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HHO38_RS13070	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HHO38_RS13220	ENOG4105DDI	hemolysin-type calcium-binding region
HHO38_RS13225	ENOG4105TT1	Ragb susd domain-containing protein
HHO38_RS13300	ENOG4105KTH	gatB Yqey
HHO38_RS13305	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HHO38_RS13310	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HHO38_RS13315	ENOG4107HJ8	Essential cell division protein (By similarity)
HHO38_RS13320	ENOG4105DFU	Cell wall formation (By similarity)
HHO38_RS13325	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HHO38_RS13330	ENOG4105CNI	cell division protein FtsW
HHO38_RS13335	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HHO38_RS13340	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HHO38_RS13345	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HHO38_RS13350	ENOG4105CJN	penicillin-binding protein
HHO38_RS13360	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HHO38_RS13390	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HHO38_RS13395	ENOG4106H78	methyltransferase
HHO38_RS13420	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HHO38_RS13435	ENOG4105CJ2	(LipO)protein
HHO38_RS13455	ENOG4105DFU	Cell wall formation (By similarity)
HHO38_RS13490	ENOG4105E2D	ec 3.2.1.52
HHO38_RS13510	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
HHO38_RS13520	ENOG4108KPZ	tonB-dependent Receptor
HHO38_RS13545	ENOG4105D49	3-dehydroquinate synthase
HHO38_RS13550	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HHO38_RS13555	ENOG4105DR5	peptidase
HHO38_RS13575	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HHO38_RS13580	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HHO38_RS13590	ENOG4108UXE	Protein tyrosine phosphatase
HHO38_RS13605	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HHO38_RS13615	ENOG4105EW9	transcriptional regulator AsnC family
HHO38_RS13650	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HHO38_RS13665	ENOG4107QIZ	NADH dehydrogenase
HHO38_RS13675	ENOG4105HEE	Binding Domain protein
HHO38_RS13695	ENOG4105EWU	Squalene--hopene cyclase
HHO38_RS13705	ENOG4105CTB	Polyprenyl synthetase
HHO38_RS13725	ENOG4105DY9	regulatoR
HHO38_RS13735	ENOG41068JE	domain protein
HHO38_RS13745	ENOG4105FA0	parb-like partition protein
HHO38_RS13750	ENOG4107QJE	Chromosome Partitioning Protein
HHO38_RS13770	ENOG41080R2	UPF0102 protein
HHO38_RS13780	ENOG4108Z6B	deaminase
HHO38_RS13795	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
HHO38_RS13800	ENOG4107QKA	exodeoxyribonuclease V beta
HHO38_RS13815	ENOG4105BZU	Histidine kinase
HHO38_RS13820	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HHO38_RS13835	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HHO38_RS13840	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
HHO38_RS13855	ENOG4105CIN	aminoacyl-histidine dipeptidase
HHO38_RS13865	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HHO38_RS13870	ENOG4105CJW	magnesium transporter
HHO38_RS13880	ENOG41067MG	lrgb family
HHO38_RS13885	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HHO38_RS13890	ENOG4105W5Q	DNA repair protein (RadC
HHO38_RS13905	ENOG4105CVA	phosphate
HHO38_RS13915	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HHO38_RS13965	ENOG41079HR	Phosphate-Selective Porin O and P
HHO38_RS14005	ENOG41061MV	Arylsulfatase
HHO38_RS14025	ENOG4105EMN	RNA polymerase sigma factor
HHO38_RS14035	ENOG4105BZU	Histidine kinase
HHO38_RS14040	ENOG4105BZU	Histidine kinase
HHO38_RS14050	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HHO38_RS14060	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HHO38_RS14080	ENOG4105EPC	oxidoreductase
HHO38_RS14110	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HHO38_RS14130	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HHO38_RS14135	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HHO38_RS14175	ENOG4105CK5	oxidoreductase
HHO38_RS14200	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HHO38_RS14215	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HHO38_RS14240	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HHO38_RS14250	ENOG4105CHB	tonB-dependent Receptor
HHO38_RS14260	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HHO38_RS14270	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HHO38_RS14275	ENOG4105C1A	potassium transporter peripheral membrane
HHO38_RS14280	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HHO38_RS14295	ENOG4105ECY	inositol monophosphatase
HHO38_RS14325	ENOG4105C8Y	Acetylornithine aminotransferase
HHO38_RS14370	ENOG4105CPF	Cell wall formation (By similarity)
HHO38_RS14375	ENOG4105C34	Pseudouridine synthase
HHO38_RS14380	ENOG4105D9P	serine threonine protein kinase
HHO38_RS14385	ENOG4105VG0	50S ribosomal protein l34
HHO38_RS14395	ENOG4106DYJ	
HHO38_RS14425	ENOG4105D9Q	decarboxylase (Beta subunit)
HHO38_RS14430	ENOG4105C99	atpase involved in dna repair
HHO38_RS14440	ENOG4105DYC	esterase
HHO38_RS14450	ENOG4108NEV	two component transcriptional regulator, LytTR family
HHO38_RS14485	ENOG4105EUJ	GTP cyclohydrolase i
HHO38_RS14495	ENOG4105CP7	Triose-phosphate isomerase
HHO38_RS14510	ENOG4105DR5	peptidase
HHO38_RS14530	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HHO38_RS14540	ENOG4108VVK	transcriptional Regulator, AsnC
HHO38_RS14545	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HHO38_RS14555	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HHO38_RS14585	ENOG4105DFD	Na H antiporter
HHO38_RS14590	ENOG4105DFD	Na H antiporter
HHO38_RS14605	ENOG4107RE3	peptidase, S41
HHO38_RS14630	ENOG4108HRK	Histidine kinase
HHO38_RS14645	ENOG4105DWU	Membrane
HHO38_RS14670	ENOG4105K8R	UPF0145 protein
HHO38_RS14710	ENOG4105BZU	Histidine kinase
HHO38_RS14720	ENOG4105EBR	Carboxylesterase
HHO38_RS14730	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS14775	ENOG4106PHI	plasmid recombination enzyme
HHO38_RS14785	ENOG4105VTR	Integrase
HHO38_RS14815	ENOG4108IQE	Amp-dependent synthetase and ligase
HHO38_RS14820	ENOG4105K7K	Transcriptional regulator
HHO38_RS14835	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HHO38_RS14845	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HHO38_RS14890	ENOG4107GFK	fumarate
HHO38_RS14910	ENOG4105CI3	gtp-binding protein typa
HHO38_RS14915	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HHO38_RS14925	ENOG4105CEY	Amp-dependent synthetase and ligase
HHO38_RS14935	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HHO38_RS14940	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HHO38_RS14945	ENOG4107Y2G	Glycosyl transferase (Group 1
HHO38_RS14995	ENOG4105D5D	udp-galactopyranose mutase
HHO38_RS15000	ENOG4105PSV	Polysaccharide Biosynthesis Protein
HHO38_RS15025	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HHO38_RS15075	ENOG4105ID8	Transcriptional regulator, ARAC family
HHO38_RS15080	ENOG4105C0P	Mg chelatase subunit ChlI
HHO38_RS15090	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HHO38_RS15095	ENOG4105DQU	oxidoreductase, subunit beta
HHO38_RS15100	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
HHO38_RS15105	ENOG4105DCF	alanine dehydrogenase
HHO38_RS15110	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HHO38_RS15135	ENOG4108B1Q	Ribonuclease
HHO38_RS15190	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HHO38_RS15215	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
HHO38_RS15220	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HHO38_RS15225	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HHO38_RS15230	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HHO38_RS15235	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HHO38_RS15245	ENOG4105CTQ	phosphohexokinase
HHO38_RS15260	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
HHO38_RS15280	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HHO38_RS15290	ENOG4105C19	ABC transporter
HHO38_RS15295	ENOG4105C8N	cysteinyl-tRNA synthetase
HHO38_RS15380	ENOG4105D4Y	metalloprotease
HHO38_RS15390	ENOG4105C9K	Endothelin-converting enzyme 1
HHO38_RS15400	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HHO38_RS15405	ENOG4105C3F	Signal peptidase i
HHO38_RS15420	ENOG4107STF	Involved in phosphonate degradation (By similarity)
HHO38_RS15425	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
HHO38_RS15545	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS15565	ENOG4106HBN	Galactosamine-6-phosphate isomerase
HHO38_RS15570	ENOG4105E2R	ROK family
HHO38_RS15585	ENOG4105CUZ	uba thif-type nad fad binding protein
HHO38_RS15590	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HHO38_RS15630	ENOG4105C8J	)-transporter
HHO38_RS15665	ENOG4105C2J	ABC transporter
HHO38_RS15675	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS15690	ENOG4105C1V	Peptidase, M16
HHO38_RS15705	ENOG4105C2X	Arabinose 5-phosphate isomerase
HHO38_RS15725	ENOG4105C5Z	peptidase
HHO38_RS15730	ENOG4105DZW	Dipeptidase
HHO38_RS15740	ENOG4105CZH	peptidase
HHO38_RS15750	ENOG4105BZU	Histidine kinase
HHO38_RS15760	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HHO38_RS15790	ENOG4108S01	response regulator
HHO38_RS15795	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HHO38_RS15825	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HHO38_RS15845	ENOG4107QRS	glycosyltransferase group 2 family protein
HHO38_RS15860	ENOG4108JJA	ABC, transporter
HHO38_RS15870	ENOG4105E2R	ROK family
HHO38_RS15875	ENOG4107SCR	N-acetylneuraminate lyase
HHO38_RS15905	ENOG4105E2D	ec 3.2.1.52
HHO38_RS15915	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
HHO38_RS15935	ENOG4108URH	decarboxylase
HHO38_RS15950	ENOG4105C5I	Dehydrogenase
HHO38_RS15955	ENOG4108JIC	nucleoside recognition domain protein
HHO38_RS15960	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HHO38_RS15980	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HHO38_RS15985	ENOG4105CPN	adenine deaminase
HHO38_RS15990	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HHO38_RS15995	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HHO38_RS16000	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
HHO38_RS16005	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HHO38_RS16010	ENOG4105EAH	synthase
HHO38_RS16015	ENOG4105C2M	dna polymerase I
HHO38_RS16020	ENOG4105IUR	peptidase C10
HHO38_RS16055	ENOG4105C3G	gtp-binding protein
HHO38_RS16060	ENOG4108MR6	WD40-like Beta Propeller Repeat
HHO38_RS16065	ENOG41075H3	AraC family transcriptional regulator
HHO38_RS16110	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HHO38_RS16115	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HHO38_RS16160	ENOG4105C8T	Leucyl-tRNA synthetase
HHO38_RS16170	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HHO38_RS16190	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HHO38_RS16195	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HHO38_RS16205	ENOG4105F5P	DNA-damage-inducible protein d
HHO38_RS16220	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHO38_RS16285	ENOG4105CHH	sulfate transporter
HHO38_RS16290	ENOG4108RAC	Rubrerythrin
HHO38_RS16295	ENOG4108IYU	L-aspartate oxidase
HHO38_RS16320	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS16330	ENOG4105UQX	Mate efflux family protein
HHO38_RS16375	ENOG4107QN2	dihydrolipoyl dehydrogenase
HHO38_RS16390	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HHO38_RS16395	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HHO38_RS16405	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HHO38_RS16410	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HHO38_RS16425	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS16470	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HHO38_RS16475	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HHO38_RS16500	ENOG4107AYK	membrAne
HHO38_RS16505	ENOG4107RAN	Peptidase, M16
HHO38_RS16520	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HHO38_RS16540	ENOG4105FDK	ABC transporter
HHO38_RS16550	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HHO38_RS16615	ENOG4105C3F	Signal peptidase i
HHO38_RS16640	ENOG4105D7W	serine acetyltransferase
HHO38_RS16645	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HHO38_RS16650	ENOG4105C5Z	peptidase
HHO38_RS16655	ENOG4105C12	Phosphoribosylglycinamide synthetase
HHO38_RS16680	ENOG4105CWC	Acetylornithine deacetylase
HHO38_RS16685	ENOG4105DTN	riboflavin biosynthesis protein ribF
HHO38_RS16690	ENOG4105EMN	RNA polymerase sigma factor
HHO38_RS16695	ENOG4105BZU	Histidine kinase
HHO38_RS16710	ENOG4105CNT	hydrolase family 2
HHO38_RS16720	ENOG4105EZR	dyp-type peroxidase family protein
HHO38_RS16755	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS16775	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS16860	ENOG4105BZW	Glycerate kinase
HHO38_RS16865	ENOG4107QQ0	gntp family
HHO38_RS16920	ENOG4105CWX	Alpha-1,2-mannosidase
HHO38_RS16935	ENOG4105DU6	RNA polymerase
HHO38_RS16985	ENOG4105CWX	Alpha-1,2-mannosidase
HHO38_RS17000	ENOG4105CWX	Alpha-1,2-mannosidase
HHO38_RS17010	ENOG4107UWA	esterase
HHO38_RS17015	ENOG4107S18	3-phosphoshikimate 1-carboxyvinyltransferase
HHO38_RS17045	ENOG4105CI2	imidazolone-5-propionate hydrolase
HHO38_RS17055	ENOG4105EAM	Na Pi-cotransporter
HHO38_RS17125	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HHO38_RS17135	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HHO38_RS17140	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HHO38_RS17145	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HHO38_RS17150	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HHO38_RS17205	ENOG4105D2H	Uronic isomerase
HHO38_RS17220	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HHO38_RS17225	ENOG4105CFP	Peptidase U32
HHO38_RS17255	ENOG4105DF5	DNA topoisomerase IV, subunit A
HHO38_RS17290	ENOG4105WEF	catalase
HHO38_RS17300	ENOG4105RWF	major outer membrane protein OmpA
HHO38_RS17310	ENOG4105EMN	RNA polymerase sigma factor
HHO38_RS17320	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HHO38_RS17325	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
HHO38_RS17335	ENOG4105DY9	regulatoR
HHO38_RS17345	ENOG4105BZU	Histidine kinase
HHO38_RS17355	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HHO38_RS17395	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS17410	ENOG4105D78	K07001 NTE family protein
HHO38_RS17430	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HHO38_RS17445	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HHO38_RS17530	ENOG4105F32	YngK protein
HHO38_RS17550	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HHO38_RS17560	ENOG4105FTV	AraC Family Transcriptional Regulator
HHO38_RS17570	ENOG4105DKQ	ROK family
HHO38_RS17580	ENOG4105C54	Major Facilitator superfamily
HHO38_RS17610	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS17615	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HHO38_RS17620	ENOG4105CA9	Pyruvate kinase
HHO38_RS17630	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HHO38_RS17635	ENOG4107VCI	FtsX-like permease family
HHO38_RS17640	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HHO38_RS17650	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HHO38_RS17665	ENOG4107Y7Q	pfkb domain protein
HHO38_RS17755	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS17760	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS17815	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HHO38_RS17820	ENOG4105BZU	Histidine kinase
HHO38_RS17850	ENOG4108UW5	maltose o-acetyltransferase
HHO38_RS17870	ENOG4105EQD	regulatoR
HHO38_RS17875	ENOG4105CPF	Cell wall formation (By similarity)
HHO38_RS17890	ENOG4107S5I	aldo keto reductase
HHO38_RS17935	ENOG4108ZQX	ybak prolyl-trna synthetase
HHO38_RS17965	ENOG4108Q9V	regulatoR
HHO38_RS17970	ENOG4105EIG	urea carboxylase-associated protein 1
HHO38_RS18010	ENOG4105W5Q	DNA repair protein (RadC
HHO38_RS18030	ENOG4105DSF	transport protein
HHO38_RS18035	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HHO38_RS18040	ENOG4108NEV	two component transcriptional regulator, LytTR family
HHO38_RS18045	ENOG4105C2F	Histidine kinase
HHO38_RS18050	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HHO38_RS18055	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HHO38_RS18060	ENOG4105CW7	secretion protein, HlyD family
HHO38_RS18070	ENOG4105FGV	Chromate
HHO38_RS18080	ENOG4105CN1	protease
HHO38_RS18085	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HHO38_RS18090	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
HHO38_RS18105	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HHO38_RS18115	ENOG4105K8N	protein family UPF0079, ATPase
HHO38_RS18120	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HHO38_RS18160	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS18185	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HHO38_RS18220	ENOG4105EXC	Acyl-transferase
HHO38_RS18235	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HHO38_RS18265	ENOG4105E6M	Sulphatase-modifying factor protein
HHO38_RS18280	ENOG4108WBT	adenosyltransferase
HHO38_RS18295	ENOG4105BZS	acriflavin resistance protein
HHO38_RS18315	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HHO38_RS18320	ENOG4105EEI	dihydropteroate synthase
HHO38_RS18330	ENOG4108IJ2	phosphate acetyltransferase
HHO38_RS18335	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HHO38_RS18340	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HHO38_RS18350	ENOG4108HKT	sucrose-6-phosphate hydrolase
HHO38_RS18365	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HHO38_RS18370	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HHO38_RS18395	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HHO38_RS18405	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HHO38_RS18420	ENOG4105CWX	Alpha-1,2-mannosidase
HHO38_RS18440	ENOG4105BZU	Histidine kinase
HHO38_RS18450	ENOG4105F1A	Pyruvate formate-lyase
HHO38_RS18460	ENOG4105D3R	alkyl hydroperoxide reductase
HHO38_RS18465	ENOG4108JU3	Alkyl hydroperoxide reductase
HHO38_RS18475	ENOG4105D05	Receptor
HHO38_RS18510	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HHO38_RS18525	ENOG4107PPM	cobalt chelatase
HHO38_RS18530	ENOG4107PPM	cobalt chelatase
HHO38_RS18535	ENOG4105D05	Receptor
HHO38_RS18540	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HHO38_RS18610	ENOG4108IJF	Heavy metal efflux pump, CzcA
HHO38_RS18625	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HHO38_RS18630	ENOG4105VFN	O-Antigen polymerase
HHO38_RS18635	ENOG4105C3F	Signal peptidase i
HHO38_RS18705	ENOG4105C31	Tryptophanyl-tRNA synthetase
HHO38_RS18725	ENOG4107RNH	Outer membrane receptor FepA
HHO38_RS18750	ENOG4105EMN	RNA polymerase sigma factor
HHO38_RS18770	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HHO38_RS18775	ENOG4105BZU	Histidine kinase
HHO38_RS18800	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HHO38_RS18805	ENOG41080VW	acetyltransferase
HHO38_RS18835	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HHO38_RS18840	ENOG4108HWS	Histidine kinase
HHO38_RS18845	ENOG4105BZU	Histidine kinase
HHO38_RS18855	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HHO38_RS18860	ENOG4105K63	Thioredoxin
HHO38_RS18865	ENOG4105C0B	DNA polymerase III (alpha subunit)
HHO38_RS18880	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HHO38_RS18885	ENOG4108UJD	30S ribosomal protein S9
HHO38_RS18890	ENOG4105CE9	30S ribosomal protein S2
HHO38_RS18895	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HHO38_RS18905	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HHO38_RS18960	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS18965	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS19105	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HHO38_RS19115	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
HHO38_RS19120	ENOG4105CHV	Transcription elongation factor NusA
HHO38_RS19125	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HHO38_RS19150	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
HHO38_RS19155	ENOG4108IUK	alpha amylase, catalytic
HHO38_RS19170	ENOG41061MV	Arylsulfatase
HHO38_RS19175	ENOG4105C9B	Cysteine desulfurase
HHO38_RS19185	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HHO38_RS19190	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HHO38_RS19205	ENOG4108Z86	Glutamine amidotransferase
HHO38_RS19210	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HHO38_RS19220	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
HHO38_RS19235	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
HHO38_RS19285	ENOG4105MZU	cell filamentation protein
HHO38_RS19325	ENOG4105CDU	Replicative dna helicase
HHO38_RS19370	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
HHO38_RS19375	ENOG41083UI	stage II sporulation protein
HHO38_RS19400	ENOG4105DGA	Diaminopimelate dehydrogenase
HHO38_RS19405	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HHO38_RS19415	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HHO38_RS19460	ENOG4105C19	ABC transporter
HHO38_RS19465	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HHO38_RS19495	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS19520	ENOG4105DKQ	ROK family
HHO38_RS19525	ENOG4105E09	nadh pyrophosphatase
HHO38_RS19540	ENOG4105BZU	Histidine kinase
HHO38_RS19545	ENOG4105BZU	Histidine kinase
HHO38_RS19550	ENOG4105BZU	Histidine kinase
HHO38_RS19600	ENOG4105C75	arginyL-tRNA synthetase
HHO38_RS19635	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HHO38_RS19640	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS19695	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HHO38_RS19710	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
HHO38_RS19725	ENOG4105CHR	reductase
HHO38_RS19730	ENOG4105CEY	Amp-dependent synthetase and ligase
HHO38_RS19750	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HHO38_RS19755	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HHO38_RS19760	ENOG4106CD9	glycosyl transferase group 1
HHO38_RS19770	ENOG4108JU4	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HHO38_RS19780	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HHO38_RS19795	ENOG4105CGP	Urocanate hydratase
HHO38_RS19800	ENOG4105CCS	Glutamate formiminotransferase
HHO38_RS19805	ENOG4105CI2	imidazolone-5-propionate hydrolase
HHO38_RS19810	ENOG410908R	Methenyltetrahydrofolate cyclohydrolase
HHO38_RS19815	ENOG4105C84	Histidine ammonia-lyase
HHO38_RS19830	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HHO38_RS19860	ENOG4105CN1	protease
HHO38_RS19865	ENOG4105DIN	metallophosphoesterase
HHO38_RS19870	ENOG4107RN3	metallophosphoesterase
HHO38_RS19875	ENOG4105ETX	regulatoR
HHO38_RS19880	ENOG4105BZU	Histidine kinase
HHO38_RS19905	ENOG4108JJA	ABC, transporter
HHO38_RS19945	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HHO38_RS19960	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS19965	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS19970	ENOG4105TT1	Ragb susd domain-containing protein
HHO38_RS19985	ENOG4105DQ5	transport system permease protein
HHO38_RS19990	ENOG4105E0A	ABC, transporter
HHO38_RS19995	ENOG4105UQX	Mate efflux family protein
HHO38_RS20005	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HHO38_RS20010	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
HHO38_RS20015	ENOG4105BZ8	glutamate synthase
HHO38_RS20050	ENOG4105CH7	arginosuccinase
HHO38_RS20060	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HHO38_RS20070	ENOG4105Y3E	Modulates RecA activity (By similarity)
HHO38_RS20075	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HHO38_RS20080	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HHO38_RS20095	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HHO38_RS20100	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HHO38_RS20115	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HHO38_RS20120	ENOG410901E	Membrane
HHO38_RS20125	ENOG4105E4C	Lytic transglycosylase catalytic
HHO38_RS20130	ENOG4105UQX	Mate efflux family protein
HHO38_RS20145	ENOG4105D05	Receptor
HHO38_RS20150	ENOG4105EHZ	conserved protein UCP016719
HHO38_RS20155	ENOG4105C5Z	peptidase
HHO38_RS20170	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HHO38_RS20175	ENOG4105CU9	asparagine synthetase A
HHO38_RS20185	ENOG4105K5X	acetyltransferase
HHO38_RS20225	ENOG4107QTF	adenylosuccinate lyase
HHO38_RS20230	ENOG4105FE9	pseudouridine synthase
HHO38_RS20235	ENOG4105C5S	asparaginyl-tRNA synthetase
HHO38_RS20240	ENOG4108VVK	transcriptional Regulator, AsnC
HHO38_RS20275	ENOG4105F8V	Hydrolase, tatD family
HHO38_RS20295	ENOG4105CAT	Cytidine monophosphate kinase
HHO38_RS20300	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HHO38_RS20305	ENOG4105CTQ	phosphohexokinase
HHO38_RS20320	ENOG4105DJT	lAO AO transport system ATPase
HHO38_RS20335	ENOG4107S85	alpha-2-macroglobulin domain protein
HHO38_RS20340	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HHO38_RS20345	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HHO38_RS20350	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HHO38_RS20375	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HHO38_RS20390	ENOG4105CZH	peptidase
HHO38_RS20410	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HHO38_RS20445	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HHO38_RS20450	ENOG4105D78	K07001 NTE family protein
HHO38_RS20465	ENOG4105DQR	SNARE associated Golgi
HHO38_RS20475	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HHO38_RS20480	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HHO38_RS20495	ENOG41090R7	Ferric uptake
HHO38_RS20500	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HHO38_RS20510	ENOG4105CUT	histidyl-tRNA synthetase
HHO38_RS20520	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HHO38_RS20525	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HHO38_RS20535	ENOG4105EMN	RNA polymerase sigma factor
HHO38_RS20550	ENOG4105DXN	mazG family
HHO38_RS20560	ENOG4105C34	Pseudouridine synthase
HHO38_RS20565	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HHO38_RS20570	ENOG4105BZU	Histidine kinase
HHO38_RS20580	ENOG4105BZU	Histidine kinase
HHO38_RS20615	ENOG4108KU3	Integrase
HHO38_RS20715	ENOG41061MV	Arylsulfatase
HHO38_RS20720	ENOG41061MV	Arylsulfatase
HHO38_RS20725	ENOG4105ENH	Sulfatase
HHO38_RS20740	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS20765	ENOG4107QUV	Domain protein
HHO38_RS20810	ENOG4105CMN	Methylmalonyl-coA mutase
HHO38_RS20815	ENOG4105D5P	Methylmalonyl-coA mutase
HHO38_RS20830	ENOG4105C25	Primosomal protein n'
HHO38_RS20870	ENOG41063TF	transcriptional regulator (AraC
HHO38_RS20875	ENOG4105CTJ	Metal Dependent Phosphohydrolase
HHO38_RS20880	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HHO38_RS20905	ENOG4108Z0R	Transferase
HHO38_RS20910	ENOG4105DC7	peptidase M24
HHO38_RS20925	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HHO38_RS20930	ENOG41083X6	30S ribosomal protein S21
HHO38_RS20935	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS20940	ENOG4105MS2	ribosomal subunit Interface protein
HHO38_RS20965	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HHO38_RS20980	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HHO38_RS20985	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HHO38_RS20990	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HHO38_RS20995	ENOG4107VNI	ribosomal protein l10
HHO38_RS21000	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HHO38_RS21005	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HHO38_RS21010	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HHO38_RS21035	ENOG4105BZU	Histidine kinase
HHO38_RS21040	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HHO38_RS21045	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HHO38_RS21050	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HHO38_RS21070	ENOG4105C26	Dehydrogenase
HHO38_RS21080	ENOG4105II7	pyrroline-5-carboxylate reductase
HHO38_RS21140	ENOG4105N5T	Radical SAM Protein
HHO38_RS21150	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HHO38_RS21165	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HHO38_RS21180	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HHO38_RS21185	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HHO38_RS21190	ENOG4105J5G	Transferase hexapeptide repeat containing protein
HHO38_RS21195	ENOG4105CWX	Alpha-1,2-mannosidase
HHO38_RS21200	ENOG4107QJQ	Mate efflux family protein
HHO38_RS21210	ENOG4105D3G	Pseudouridine synthase
HHO38_RS21240	ENOG4105KNA	-acetyltransferase
HHO38_RS21245	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HHO38_RS21250	ENOG4105ECP	epimerase
HHO38_RS21270	ENOG4105CPQ	Dehydrogenase
HHO38_RS21280	ENOG4105MZU	cell filamentation protein
HHO38_RS21305	ENOG4105DZR	Type I site-specific deoxyribonuclease
HHO38_RS21330	ENOG4108V4B	ThiJ pfpI
HHO38_RS21400	ENOG4105MZU	cell filamentation protein
HHO38_RS21425	ENOG4108F3G	Type I restriction-modification system, R subunit
HHO38_RS21430	ENOG4105CVR	type I restriction-modification system
HHO38_RS21435	ENOG4105DFS	Conserved Protein
HHO38_RS21440	ENOG4107QTH	restriction modification system DNA specificity domain
HHO38_RS21485	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
HHO38_RS21505	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS21705	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HHO38_RS21775	ENOG4105VRT	cytoplasmic protein
HHO38_RS21845	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHO38_RS21850	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HHO38_RS21865	ENOG4108DBC	nitroreductase
HHO38_RS21870	ENOG4105E66	phosphoriboisomerase A
HHO38_RS21875	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HHO38_RS21880	ENOG4105DI5	UPF0365 protein
HHO38_RS21895	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HHO38_RS21905	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HHO38_RS21920	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HHO38_RS21925	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HHO38_RS21930	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HHO38_RS21935	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HHO38_RS21940	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HHO38_RS21945	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HHO38_RS21950	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HHO38_RS21960	ENOG4105KG3	cytidine deaminase
HHO38_RS21970	ENOG4105DR5	peptidase
HHO38_RS21975	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HHO38_RS21990	ENOG4105CIN	aminoacyl-histidine dipeptidase
HHO38_RS22015	ENOG4105C6E	dna polymerase iii
HHO38_RS22020	ENOG4105C26	Dehydrogenase
HHO38_RS22025	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HHO38_RS22035	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HHO38_RS22045	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HHO38_RS22050	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HHO38_RS22055	ENOG4105C87	Aminotransferase class I and II
HHO38_RS22060	ENOG4105C01	Dihydroxy-acid dehydratase
HHO38_RS22065	ENOG4105C7K	acetolactate synthase
HHO38_RS22080	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HHO38_RS22095	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HHO38_RS22100	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HHO38_RS22105	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HHO38_RS22110	ENOG4107SDT	Homocitrate synthase
HHO38_RS22130	ENOG4105D64	Mechanosensitive ion channel
HHO38_RS22155	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HHO38_RS22165	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HHO38_RS22205	ENOG4108W3Q	Transcriptional regulator
HHO38_RS22220	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HHO38_RS22225	ENOG4105CPC	Aldo Keto reductase
HHO38_RS22230	ENOG4105ENX	hydrolase
HHO38_RS22270	ENOG4105C5H	ABC transporter
HHO38_RS22275	ENOG4105CZM	Major Facilitator
HHO38_RS22310	ENOG4105CHM	Aminotransferase
HHO38_RS22325	ENOG4107QJZ	Glycosyl transferase, family 2
HHO38_RS22330	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HHO38_RS22335	ENOG4105CFH	Aspartokinase
HHO38_RS22340	ENOG4105CAK	Cell division ATP-binding protein ftsE
HHO38_RS22345	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HHO38_RS22350	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HHO38_RS22355	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HHO38_RS22375	ENOG4108DBC	nitroreductase
HHO38_RS22385	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HHO38_RS22405	ENOG4105DYC	esterase
HHO38_RS22415	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HHO38_RS22435	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HHO38_RS22445	ENOG4105BZU	Histidine kinase
HHO38_RS22450	ENOG4105BZU	Histidine kinase
HHO38_RS22455	ENOG4105CFG	Acts as a chaperone (By similarity)
HHO38_RS22460	ENOG4105C03	ribonuclease
HHO38_RS22465	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HHO38_RS22475	ENOG4108UUM	single-stranded DNA-binding protein
HHO38_RS22480	ENOG4108JU5	Magnesium and cobalt efflux protein
HHO38_RS22490	ENOG4105W8Z	4'-phosphopantetheinyl transferase
HHO38_RS22495	ENOG4105E2X	shikimate dehydrogenase
HHO38_RS22500	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HHO38_RS22505	ENOG4107QWK	SAICAR synthetase
HHO38_RS22510	ENOG4105C9A	Phoh family
HHO38_RS22520	ENOG4108UVJ	appr-1-p processing domain protein
HHO38_RS22545	ENOG4105C7B	Threonine dehydratase
HHO38_RS22550	ENOG4105K63	Thioredoxin
HHO38_RS22555	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HHO38_RS22560	ENOG4105CNT	hydrolase family 2
HHO38_RS22580	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HHO38_RS22595	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HHO38_RS22605	ENOG4105C19	ABC transporter
HHO38_RS22610	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HHO38_RS22615	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HHO38_RS22620	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HHO38_RS22655	ENOG4108NEV	two component transcriptional regulator, LytTR family
HHO38_RS22665	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HHO38_RS22670	ENOG4105BZU	Histidine kinase
HHO38_RS22685	ENOG41081WG	50s ribosomal protein l31
HHO38_RS22690	ENOG4105D2N	Aldolase
HHO38_RS22735	ENOG4105C3F	Signal peptidase i
HHO38_RS22750	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HHO38_RS22755	ENOG4107QUV	Domain protein
HHO38_RS22760	ENOG4105MSB	protein, conserved in bacteria
HHO38_RS22770	ENOG4105D0C	transport protein
HHO38_RS22775	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HHO38_RS22800	ENOG4105US7	Histidine kinase
HHO38_RS22805	ENOG4105ETX	regulatoR
HHO38_RS22815	ENOG4108KPJ	rna polymerase sigma factor
HHO38_RS22840	ENOG4105NGQ	Thioredoxin
HHO38_RS22845	ENOG4105EQD	regulatoR
HHO38_RS22850	ENOG4108KBJ	Inner membrane protein YkgB
HHO38_RS22870	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HHO38_RS22875	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HHO38_RS22880	ENOG4105HSA	Protein of unknown function (DUF452)
HHO38_RS22885	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HHO38_RS22895	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HHO38_RS22905	ENOG4105DUX	Transporter
HHO38_RS22925	ENOG4105C27	TonB-dependent Receptor Plug
HHO38_RS22950	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HHO38_RS22960	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HHO38_RS22965	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HHO38_RS22970	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HHO38_RS22975	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHO38_RS22980	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HHO38_RS23005	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HHO38_RS23010	ENOG4105CBG	Sulfatase
HHO38_RS23015	ENOG4105C5H	ABC transporter
HHO38_RS23030	ENOG4105VXP	Protein of unknown function DUF86
HHO38_RS23040	ENOG4105DC1	bifunctional purine biosynthesis protein purh