locus-tag	class	description
BC1002_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BC1002_RS00015	COG0592	DNA-directed DNA polymerase activity
BC1002_RS00030	COG4303	Ethanolamine ammonia lyase large subunit
BC1002_RS00035	COG4302	ethanolamine ammonia-lyase activity
BC1002_RS00045	COG0789	Transcriptional regulator
BC1002_RS00055	COG0513	Belongs to the DEAD box helicase family
BC1002_RS00060	COG0436	Aminotransferase
BC1002_RS00065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS00070	COG2207	Transcriptional regulator
BC1002_RS00085	COG5001	Diguanylate cyclase
BC1002_RS00085	COG2203	Gaf domain
BC1002_RS00085	COG3706	GGDEF domain
BC1002_RS00085	COG4251	negative regulation of phosphorylation
BC1002_RS00105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC1002_RS00110	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BC1002_RS00115	COG0583	DNA-binding transcription factor activity
BC1002_RS00130	COG0758	DNA mediated transformation
BC1002_RS00130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BC1002_RS00135	COG0242	peptide deformylase activity
BC1002_RS00140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BC1002_RS00150	COG0501	Belongs to the peptidase M48B family
BC1002_RS00165	COG5000	phosphorelay sensor kinase activity
BC1002_RS00170	COG2204	response regulator
BC1002_RS00180	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BC1002_RS00185	COG0602	queuosine metabolic process
BC1002_RS00190	COG0720	synthase
BC1002_RS00205	COG0772	Belongs to the SEDS family
BC1002_RS00210	COG0768	penicillin binding
BC1002_RS00225	COG1077	Cell shape determining protein MreB Mrl
BC1002_RS00230	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BC1002_RS00235	COG0154	amidase activity
BC1002_RS00240	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BC1002_RS00245	COG2326	polyphosphate kinase activity
BC1002_RS00250	COG0708	Exodeoxyribonuclease III
BC1002_RS00260	COG2814	Major facilitator Superfamily
BC1002_RS00270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BC1002_RS00285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BC1002_RS00300	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BC1002_RS00305	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BC1002_RS00310	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BC1002_RS00320	COG0523	cobalamin synthesis protein
BC1002_RS00330	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BC1002_RS00340	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BC1002_RS00345	COG1560	Kdo2-lipid A biosynthetic process
BC1002_RS00350	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BC1002_RS00370	COG0667	Aldo Keto reductase
BC1002_RS00380	COG2814	Major facilitator Superfamily
BC1002_RS00425	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BC1002_RS00460	COG0531	amino acid
BC1002_RS00495	COG3568	Endonuclease Exonuclease Phosphatase
BC1002_RS00505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BC1002_RS00510	COG0579	oxidoreductase
BC1002_RS00530	COG2070	2-Nitropropane dioxygenase
BC1002_RS00550	COG2916	Histone family protein nucleoid-structuring protein H-NS
BC1002_RS00560	COG1522	sequence-specific DNA binding
BC1002_RS00570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC1002_RS00595	COG0792	nuclease activity
BC1002_RS00600	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BC1002_RS00625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC1002_RS00660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BC1002_RS00665	COG0443	Heat shock 70 kDa protein
BC1002_RS00795	COG5001	Diguanylate cyclase
BC1002_RS00795	COG4251	negative regulation of phosphorylation
BC1002_RS00795	COG3706	GGDEF domain
BC1002_RS00795	COG2203	Gaf domain
BC1002_RS00800	COG2233	PERMEase
BC1002_RS00805	COG0025	NhaP-type Na H and K H
BC1002_RS00810	COG2199	diguanylate cyclase activity
BC1002_RS00810	COG2200	EAL domain
BC1002_RS00855	COG1609	Transcriptional regulator
BC1002_RS00880	COG0583	DNA-binding transcription factor activity
BC1002_RS00885	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC1002_RS00885	COG1703	isobutyryl-CoA mutase activity
BC1002_RS00885	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC1002_RS00895	COG0596	Alpha beta hydrolase
BC1002_RS00935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BC1002_RS00945	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BC1002_RS00950	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BC1002_RS00955	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BC1002_RS00960	COG0156	8-amino-7-oxononanoate synthase activity
BC1002_RS00975	COG3012	SEC-C Motif Domain Protein
BC1002_RS00980	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS00990	COG0183	Belongs to the thiolase family
BC1002_RS00995	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BC1002_RS01000	COG0789	Transcriptional regulator
BC1002_RS01025	COG0747	negative chemotaxis
BC1002_RS01040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BC1002_RS01050	COG0018	arginyl-trna synthetase
BC1002_RS01065	COG1410	methionine synthase
BC1002_RS01065	COG0646	methionine synthase
BC1002_RS01120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BC1002_RS01130	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BC1002_RS01140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BC1002_RS01145	COG1127	ABC transporter
BC1002_RS01175	COG1686	Belongs to the peptidase S11 family
BC1002_RS01185	COG2921	Belongs to the UPF0250 family
BC1002_RS01190	COG0583	DNA-binding transcription factor activity
BC1002_RS01200	COG0321	lipoyl(octanoyl) transferase activity
BC1002_RS01220	COG0584	glycerophosphoryl diester phosphodiesterase
BC1002_RS01225	COG1301	dicarboxylic acid transport
BC1002_RS01230	COG4191	Histidine kinase
BC1002_RS01255	COG2960	long-chain fatty acid transporting porin activity
BC1002_RS01265	COG0004	ammonium transporteR
BC1002_RS01275	COG0189	ligase activity
BC1002_RS01285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC1002_RS01290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BC1002_RS01295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BC1002_RS01300	COG0793	Belongs to the peptidase S41A family
BC1002_RS01305	COG0588	phosphoglycerate mutase activity
BC1002_RS01310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC1002_RS01320	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BC1002_RS01325	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BC1002_RS01335	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BC1002_RS01345	COG2226	methyltransferase
BC1002_RS01360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BC1002_RS01370	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BC1002_RS01400	COG1612	heme a metabolic process
BC1002_RS01405	COG0109	protoheme IX farnesyltransferase activity
BC1002_RS01410	COG1999	signal sequence binding
BC1002_RS01425	COG0456	acetyltransferase
BC1002_RS01425	COG1846	Transcriptional regulator
BC1002_RS01430	COG2188	Transcriptional regulator
BC1002_RS01435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BC1002_RS01440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BC1002_RS01445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BC1002_RS01445	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC1002_RS01450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC1002_RS01450	COG1263	PTS System
BC1002_RS01450	COG2190	(PTS) system
BC1002_RS01460	COG1294	oxidase, subunit
BC1002_RS01475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BC1002_RS01490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC1002_RS01495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BC1002_RS01505	COG0625	glutathione transferase activity
BC1002_RS01515	COG0742	ribosomal rna small subunit methyltransferase
BC1002_RS01520	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BC1002_RS01535	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BC1002_RS01545	COG0193	aminoacyl-tRNA hydrolase activity
BC1002_RS01550	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BC1002_RS01555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BC1002_RS01565	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BC1002_RS01570	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BC1002_RS01580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BC1002_RS01585	COG1194	a g-specific adenine glycosylase
BC1002_RS01595	COG1660	Displays ATPase and GTPase activities
BC1002_RS01600	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BC1002_RS01610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BC1002_RS01615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BC1002_RS01620	COG1137	ATPase activity
BC1002_RS01635	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BC1002_RS01650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BC1002_RS01685	COG2814	Major facilitator Superfamily
BC1002_RS01690	COG0629	single-stranded DNA binding
BC1002_RS01700	COG0840	transmembrane signaling receptor activity
BC1002_RS01715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BC1002_RS01725	COG2010	Cytochrome c
BC1002_RS01735	COG0583	DNA-binding transcription factor activity
BC1002_RS01745	COG2197	response regulator
BC1002_RS01755	COG2197	response regulator
BC1002_RS01770	COG0784	Response regulator, receiver
BC1002_RS01770	COG2205	protein histidine kinase activity
BC1002_RS01770	COG5002	protein histidine kinase activity
BC1002_RS01790	COG0477	Major facilitator Superfamily
BC1002_RS01810	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BC1002_RS01820	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BC1002_RS01820	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BC1002_RS01830	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BC1002_RS01850	COG2226	methyltransferase
BC1002_RS01865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BC1002_RS01885	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BC1002_RS01890	COG0494	nUDIX hydrolase
BC1002_RS01895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC1002_RS01905	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS01910	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC1002_RS01910	COG1024	Enoyl-CoA hydratase
BC1002_RS01915	COG0183	Belongs to the thiolase family
BC1002_RS01920	COG1024	Enoyl-CoA hydratase
BC1002_RS01925	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BC1002_RS01950	COG5265	(ABC) transporter
BC1002_RS01955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BC1002_RS01965	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BC1002_RS01970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BC1002_RS01975	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BC1002_RS01980	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BC1002_RS02000	COG0765	amino acid transport
BC1002_RS02005	COG0765	amino acid transport
BC1002_RS02025	COG0204	Acyl-transferase
BC1002_RS02030	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BC1002_RS02035	COG0751	glycine-tRNA ligase activity
BC1002_RS02040	COG0752	glycyl-tRNA synthetase alpha subunit
BC1002_RS02110	COG1051	belongs to the nudix hydrolase family
BC1002_RS02175	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
BC1002_RS02180	COG0631	protein serine/threonine phosphatase activity
BC1002_RS02185	COG4245	von Willebrand factor, type A
BC1002_RS02205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC1002_RS02205	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BC1002_RS02215	COG3157	Type VI secretion system effector, Hcp
BC1002_RS02235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BC1002_RS02260	COG0482	sulfurtransferase activity
BC1002_RS02295	COG0840	transmembrane signaling receptor activity
BC1002_RS02310	COG3008	intermembrane lipid transfer
BC1002_RS02315	COG2995	paraquat-inducible protein a
BC1002_RS02335	COG2353	YceI-like domain
BC1002_RS02345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC1002_RS02350	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC1002_RS02355	COG1862	Preprotein translocase
BC1002_RS02360	COG0343	queuine tRNA-ribosyltransferase activity
BC1002_RS02365	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BC1002_RS02370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BC1002_RS02380	COG0753	catalase activity
BC1002_RS02385	COG0783	Belongs to the Dps family
BC1002_RS02390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BC1002_RS02405	COG0247	lactate metabolic process
BC1002_RS02410	COG0277	FAD linked oxidase domain protein
BC1002_RS02415	COG0277	FAD linked oxidase domain protein
BC1002_RS02420	COG0277	FAD linked oxidase domain protein
BC1002_RS02425	COG2096	Adenosyltransferase
BC1002_RS02440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BC1002_RS02445	COG0312	modulator of DNA gyrase
BC1002_RS02450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC1002_RS02460	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BC1002_RS02465	COG0497	DNA recombination
BC1002_RS02470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BC1002_RS02475	COG1420	regulation of RNA biosynthetic process
BC1002_RS02480	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BC1002_RS02490	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BC1002_RS02495	COG0443	Heat shock 70 kDa protein
BC1002_RS02500	COG0484	heat shock protein binding
BC1002_RS02510	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BC1002_RS02515	COG1428	Deoxynucleoside kinase
BC1002_RS02525	COG0617	tRNA 3'-terminal CCA addition
BC1002_RS02535	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BC1002_RS02545	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BC1002_RS02550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BC1002_RS02555	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BC1002_RS02560	COG0586	Pfam SNARE associated Golgi protein
BC1002_RS02600	COG0823	Involved in the tonB-independent uptake of proteins
BC1002_RS02620	COG0824	Thioesterase
BC1002_RS02625	COG4221	oxidoreductase activity
BC1002_RS02635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BC1002_RS02680	COG0450	alkyl hydroperoxide reductase
BC1002_RS02685	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS02735	COG2814	Major facilitator Superfamily
BC1002_RS02755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC1002_RS02760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BC1002_RS02830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BC1002_RS02855	COG2823	Periplasmic or secreted lipoprotein
BC1002_RS02865	COG0730	response to heat
BC1002_RS02875	COG0583	DNA-binding transcription factor activity
BC1002_RS02880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC1002_RS02885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC1002_RS02890	COG2271	Major facilitator Superfamily
BC1002_RS02900	COG0662	Cupin 2, conserved barrel domain protein
BC1002_RS02900	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BC1002_RS02910	COG1596	polysaccharide export
BC1002_RS02915	COG3206	protein involved in exopolysaccharide biosynthesis
BC1002_RS02915	COG0489	protein tyrosine kinase activity
BC1002_RS02935	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BC1002_RS02940	COG0459	protein refolding
BC1002_RS02945	COG0529	Catalyzes the synthesis of activated sulfate
BC1002_RS02960	COG1773	rubredoxin
BC1002_RS02970	COG1678	Uncharacterized ACR, COG1678
BC1002_RS02975	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BC1002_RS02980	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BC1002_RS02985	COG0540	Belongs to the ATCase OTCase family
BC1002_RS03000	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BC1002_RS03005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC1002_RS03035	COG0662	Cupin 2, conserved barrel domain protein
BC1002_RS03035	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BC1002_RS03060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BC1002_RS03065	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS03075	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BC1002_RS03075	COG0546	phosphoglycolate phosphatase activity
BC1002_RS03110	COG1063	alcohol dehydrogenase
BC1002_RS03150	COG1216	Glycosyl transferase, family 2
BC1002_RS03150	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS03165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BC1002_RS03200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BC1002_RS03205	COG0840	transmembrane signaling receptor activity
BC1002_RS03215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BC1002_RS03260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BC1002_RS03265	COG0830	nickel cation binding
BC1002_RS03270	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BC1002_RS03280	COG0832	Belongs to the urease beta subunit family
BC1002_RS03285	COG0831	urea catabolic process
BC1002_RS03290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS03295	COG0829	nickel cation binding
BC1002_RS03350	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BC1002_RS03365	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS03370	COG1879	ABC-type sugar transport system periplasmic component
BC1002_RS03380	COG0673	inositol 2-dehydrogenase activity
BC1002_RS03410	COG0583	DNA-binding transcription factor activity
BC1002_RS03415	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC1002_RS03425	COG0175	sulfate reduction
BC1002_RS03435	COG2895	sulfate adenylyltransferase (ATP) activity
BC1002_RS03440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BC1002_RS03440	COG1648	precorrin-2 dehydrogenase activity
BC1002_RS03460	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BC1002_RS03475	COG4654	Cytochrome c, class I
BC1002_RS03485	COG0583	DNA-binding transcription factor activity
BC1002_RS03490	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BC1002_RS03515	COG4206	TonB-dependent receptor
BC1002_RS03520	COG4139	cobalamin transport
BC1002_RS03525	COG1120	ATPase activity
BC1002_RS03530	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BC1002_RS03535	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BC1002_RS03545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC1002_RS03565	COG1492	cobalamin metabolic process
BC1002_RS03580	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BC1002_RS03585	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BC1002_RS03590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BC1002_RS03610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC1002_RS03610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC1002_RS03620	COG0489	protein tyrosine kinase activity
BC1002_RS03630	COG0717	Belongs to the dCTP deaminase family
BC1002_RS03645	COG3781	membrane
BC1002_RS03650	COG1737	Transcriptional regulator
BC1002_RS03650	COG0837	glucose binding
BC1002_RS03660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BC1002_RS03670	COG1175	transmembrane transport
BC1002_RS03675	COG0395	ABC-type sugar transport system, permease component
BC1002_RS03680	COG3842	ATPase activity
BC1002_RS03695	COG2840	Smr protein MutS2
BC1002_RS03700	COG0492	ferredoxin-NADP+ reductase activity
BC1002_RS03705	COG1674	ftsk spoiiie
BC1002_RS03710	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BC1002_RS03725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BC1002_RS03730	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BC1002_RS03745	COG0024	Methionine aminopeptidase
BC1002_RS03755	COG0850	regulation of cytokinetic process
BC1002_RS03760	COG2894	cell division
BC1002_RS03765	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BC1002_RS03775	COG0038	chloride channel
BC1002_RS03780	COG0859	PFAM glycosyl transferase family 9
BC1002_RS03795	COG0477	Major facilitator Superfamily
BC1002_RS03805	COG0165	Argininosuccinate lyase
BC1002_RS03815	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BC1002_RS03820	COG0181	hydroxymethylbilane synthase activity
BC1002_RS03835	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS03875	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS03880	COG3284	Transcriptional regulator
BC1002_RS03900	COG2271	Major facilitator Superfamily
BC1002_RS03915	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BC1002_RS03925	COG2827	Endonuclease containing a URI domain
BC1002_RS03960	COG4215	(ABC) transporter
BC1002_RS03965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS03975	COG1741	Belongs to the pirin family
BC1002_RS04005	COG1176	ABC-type spermidine putrescine transport system, permease component I
BC1002_RS04010	COG1116	anion transmembrane transporter activity
BC1002_RS04025	COG2204	response regulator
BC1002_RS04045	COG2204	response regulator
BC1002_RS04060	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BC1002_RS04065	COG2814	Major facilitator Superfamily
BC1002_RS04070	COG1881	PFAM PEBP family protein
BC1002_RS04075	COG3727	T/G mismatch-specific endonuclease activity
BC1002_RS04100	COG0625	glutathione transferase activity
BC1002_RS04110	COG2226	methyltransferase
BC1002_RS04120	COG1773	rubredoxin
BC1002_RS04130	COG0488	(ABC) transporter
BC1002_RS04150	COG2059	Chromate
BC1002_RS04160	COG0384	phenazine biosynthesis protein PhzF
BC1002_RS04170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC1002_RS04180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC1002_RS04185	COG0326	Molecular chaperone. Has ATPase activity
BC1002_RS04190	COG3161	chorismate lyase activity
BC1002_RS04200	COG0456	acetyltransferase
BC1002_RS04205	COG0662	Cupin 2, conserved barrel domain protein
BC1002_RS04245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BC1002_RS04250	COG3135	benzoate transporter
BC1002_RS04280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BC1002_RS04285	COG2878	Part of a membrane complex involved in electron transport
BC1002_RS04290	COG1309	transcriptional regulator
BC1002_RS04300	COG3387	PFAM Glycoside hydrolase 15-related
BC1002_RS04310	COG2706	6-phosphogluconolactonase activity
BC1002_RS04315	COG1674	ftsk spoiiie
BC1002_RS04315	COG1674	ftsk spoiiie
BC1002_RS04325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BC1002_RS04345	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS04350	COG0513	Belongs to the DEAD box helicase family
BC1002_RS04360	COG1054	Belongs to the UPF0176 family
BC1002_RS04370	COG0463	Glycosyl transferase, family 2
BC1002_RS04375	COG1132	(ABC) transporter
BC1002_RS04380	COG1215	transferase activity, transferring glycosyl groups
BC1002_RS04455	COG1956	GAF domain-containing protein
BC1002_RS04475	COG1530	ribonuclease E activity
BC1002_RS04480	COG0424	maF-like protein
BC1002_RS04485	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BC1002_RS04490	COG0799	negative regulation of ribosome biogenesis
BC1002_RS04495	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BC1002_RS04500	COG0408	coproporphyrinogen oxidase activity
BC1002_RS04505	COG0151	Belongs to the GarS family
BC1002_RS04510	COG0217	transcriptional regulatory protein
BC1002_RS04515	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BC1002_RS04520	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS04545	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BC1002_RS04550	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BC1002_RS04555	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BC1002_RS04560	COG2205	protein histidine kinase activity
BC1002_RS04565	COG0745	RESPONSE REGULATOR receiver
BC1002_RS04570	COG2076	Multidrug Resistance protein
BC1002_RS04580	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BC1002_RS04595	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BC1002_RS04600	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS04610	COG1309	transcriptional regulator
BC1002_RS04620	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS04655	COG0028	Belongs to the TPP enzyme family
BC1002_RS04665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BC1002_RS04670	COG0688	phosphatidylethanolamine metabolic process
BC1002_RS04675	COG1183	phosphatidylcholine synthase activity
BC1002_RS04680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC1002_RS04685	COG0659	secondary active sulfate transmembrane transporter activity
BC1002_RS04690	COG0288	reversible hydration of carbon dioxide
BC1002_RS04700	COG0683	leucine binding
BC1002_RS04705	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BC1002_RS04710	COG1185	polyribonucleotide nucleotidyltransferase activity
BC1002_RS04715	COG3321	synthase
BC1002_RS04715	COG0604	alcohol dehydrogenase
BC1002_RS04715	COG4221	oxidoreductase activity
BC1002_RS04715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC1002_RS04720	COG0149	triose-phosphate isomerase activity
BC1002_RS04735	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC1002_RS04740	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC1002_RS04745	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC1002_RS04750	COG0649	NAD binding
BC1002_RS04765	COG1034	ATP synthesis coupled electron transport
BC1002_RS04770	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BC1002_RS04775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC1002_RS04785	COG0713	ATP synthesis coupled electron transport
BC1002_RS04800	COG1007	ATP synthesis coupled electron transport
BC1002_RS04810	COG0494	nUDIX hydrolase
BC1002_RS04825	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS04830	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS04845	COG0625	glutathione transferase activity
BC1002_RS04850	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS04865	COG1024	Enoyl-CoA hydratase
BC1002_RS04870	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC1002_RS04875	COG0625	glutathione transferase activity
BC1002_RS04880	COG0436	Aminotransferase
BC1002_RS04890	COG3022	response to hydroperoxide
BC1002_RS04895	COG2866	Carboxypeptidase
BC1002_RS04920	COG0628	permease
BC1002_RS04975	COG0582	viral genome integration into host DNA
BC1002_RS05010	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BC1002_RS05015	COG0667	Aldo Keto reductase
BC1002_RS05020	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS05035	COG0556	nucleotide-excision repair
BC1002_RS05045	COG4633	Protein conserved in bacteria
BC1002_RS05050	COG0672	)-iron permease
BC1002_RS05110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BC1002_RS05130	COG0697	spore germination
BC1002_RS05135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC1002_RS05145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC1002_RS05160	COG2205	protein histidine kinase activity
BC1002_RS05160	COG0784	Response regulator, receiver
BC1002_RS05160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS05160	COG2198	Histidine kinase
BC1002_RS05170	COG1320	monovalent cation:proton antiporter activity
BC1002_RS05175	COG2212	antiporter activity
BC1002_RS05180	COG1863	multisubunit Na H antiporter MnhE subunit
BC1002_RS05185	COG0651	ATP synthesis coupled electron transport
BC1002_RS05190	COG1006	Multisubunit Na H antiporter MnhC subunit
BC1002_RS05195	COG2111	Na H antiporter
BC1002_RS05195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BC1002_RS05200	COG2814	Major facilitator Superfamily
BC1002_RS05210	COG0784	Response regulator, receiver
BC1002_RS05210	COG0835	chemotaxis
BC1002_RS05225	COG0667	Aldo Keto reductase
BC1002_RS05230	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS05235	COG0583	DNA-binding transcription factor activity
BC1002_RS05245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BC1002_RS05275	COG1215	transferase activity, transferring glycosyl groups
BC1002_RS05280	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BC1002_RS05305	COG1215	transferase activity, transferring glycosyl groups
BC1002_RS05310	COG2194	sulfuric ester hydrolase activity
BC1002_RS05335	COG1473	amidohydrolase
BC1002_RS05360	COG1845	cytochrome c oxidase, subunit III
BC1002_RS05365	COG1845	cytochrome c oxidase, subunit III
BC1002_RS05370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BC1002_RS05375	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BC1002_RS05395	COG2252	PERMEase
BC1002_RS05415	COG0583	DNA-binding transcription factor activity
BC1002_RS05420	COG2986	histidine ammonia-lyase
BC1002_RS05430	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BC1002_RS05440	COG1228	amidohydrolase
BC1002_RS05475	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BC1002_RS05485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BC1002_RS05495	COG2345	Transcriptional regulator
BC1002_RS05515	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS05520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC1002_RS05535	COG1752	Esterase of the alpha-beta hydrolase superfamily
BC1002_RS05560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BC1002_RS05575	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS05580	COG3724	N-succinylarginine dihydrolase activity
BC1002_RS05585	COG2988	succinylglutamate desuccinylase activity
BC1002_RS05610	COG2202	Pas domain
BC1002_RS05610	COG2200	EAL domain
BC1002_RS05610	COG2199	diguanylate cyclase activity
BC1002_RS05615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BC1002_RS05635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BC1002_RS05650	COG4566	intracellular signal transduction
BC1002_RS05655	COG4191	Histidine kinase
BC1002_RS05660	COG4566	intracellular signal transduction
BC1002_RS05665	COG4566	intracellular signal transduction
BC1002_RS05670	COG0596	Alpha beta hydrolase
BC1002_RS05685	COG0154	amidase activity
BC1002_RS05700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BC1002_RS05705	COG0004	ammonium transporteR
BC1002_RS05710	COG4251	negative regulation of phosphorylation
BC1002_RS05740	COG0300	oxidoreductase activity
BC1002_RS05750	COG1959	2 iron, 2 sulfur cluster binding
BC1002_RS05755	COG2910	NAD(P)H-binding
BC1002_RS05760	COG0668	transmembrane transport
BC1002_RS05770	COG1522	sequence-specific DNA binding
BC1002_RS05785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BC1002_RS05790	COG1074	ATP-dependent DNA helicase activity
BC1002_RS05795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BC1002_RS05810	COG2200	EAL domain
BC1002_RS05830	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BC1002_RS05850	COG0583	DNA-binding transcription factor activity
BC1002_RS05855	COG0436	Aminotransferase
BC1002_RS05860	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BC1002_RS05870	COG0779	Required for maturation of 30S ribosomal subunits
BC1002_RS05875	COG0195	Participates in both transcription termination and antitermination
BC1002_RS05875	COG2251	uridine kinase activity
BC1002_RS05880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BC1002_RS05885	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BC1002_RS05890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BC1002_RS05895	COG2814	Major facilitator Superfamily
BC1002_RS05900	COG1566	PFAM secretion protein HlyD family protein
BC1002_RS05915	COG1217	gtp-binding protein TYPA
BC1002_RS05920	COG0567	Dehydrogenase, E1 component
BC1002_RS05925	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC1002_RS05930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BC1002_RS05935	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BC1002_RS05965	COG1923	regulation of RNA biosynthetic process
BC1002_RS05995	COG0318	PFAM AMP-dependent synthetase and ligase
BC1002_RS06000	COG0183	Belongs to the thiolase family
BC1002_RS06015	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS06025	COG2814	Major facilitator Superfamily
BC1002_RS06030	COG1295	ribonuclease BN
BC1002_RS06065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC1002_RS06070	COG2205	protein histidine kinase activity
BC1002_RS06070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS06090	COG0583	DNA-binding transcription factor activity
BC1002_RS06100	COG3795	YCII-related domain
BC1002_RS06135	COG0628	permease
BC1002_RS06160	COG0542	response to heat
BC1002_RS06175	COG0058	SHG alpha-glucan phosphorylase activity
BC1002_RS06185	COG0587	DNA-directed DNA polymerase activity
BC1002_RS06210	COG0583	DNA-binding transcription factor activity
BC1002_RS06215	COG1301	dicarboxylic acid transport
BC1002_RS06230	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BC1002_RS06260	COG3284	Transcriptional regulator
BC1002_RS06270	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS06275	COG0583	DNA-binding transcription factor activity
BC1002_RS06295	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS06300	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS06330	COG0557	exoribonuclease II activity
BC1002_RS06335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC1002_RS06350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC1002_RS06365	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BC1002_RS06370	COG0297	glycogen (starch) synthase activity
BC1002_RS06380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC1002_RS06400	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BC1002_RS06410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC1002_RS06440	COG1802	Transcriptional regulator
BC1002_RS06445	COG0673	inositol 2-dehydrogenase activity
BC1002_RS06450	COG0765	amino acid transport
BC1002_RS06455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS06460	COG0167	dihydroorotate dehydrogenase activity
BC1002_RS06465	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BC1002_RS06470	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BC1002_RS06485	COG4702	Belongs to the UPF0303 family
BC1002_RS06535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC1002_RS06540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC1002_RS06545	COG1116	anion transmembrane transporter activity
BC1002_RS06580	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BC1002_RS06600	COG3530	Putative quorum-sensing-regulated virulence factor
BC1002_RS06605	COG0667	Aldo Keto reductase
BC1002_RS06630	COG1131	(ABC) transporter
BC1002_RS06650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BC1002_RS06655	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BC1002_RS06660	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BC1002_RS06665	COG4208	sulfate ABC transporter
BC1002_RS06670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BC1002_RS06675	COG0583	DNA-binding transcription factor activity
BC1002_RS06695	COG0252	asparaginase activity
BC1002_RS06700	COG2084	Dehydrogenase
BC1002_RS06705	COG3622	Belongs to the hyi family
BC1002_RS06710	COG3960	tartronate-semialdehyde synthase activity
BC1002_RS06715	COG0583	DNA-binding transcription factor activity
BC1002_RS06720	COG1595	DNA-templated transcription, initiation
BC1002_RS06740	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BC1002_RS06745	COG0359	binds to the 23S rRNA
BC1002_RS06760	COG0306	phosphate transporter
BC1002_RS06765	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS06770	COG0791	NLP P60 protein
BC1002_RS06775	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BC1002_RS06780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BC1002_RS06785	COG0726	polysaccharide deacetylase
BC1002_RS06790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BC1002_RS06790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC1002_RS06800	COG0463	Glycosyl transferase, family 2
BC1002_RS06805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BC1002_RS06810	COG2076	Multidrug Resistance protein
BC1002_RS06815	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BC1002_RS06825	COG0436	Aminotransferase
BC1002_RS06845	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BC1002_RS06850	COG0314	molybdopterin synthase activity
BC1002_RS06855	COG2346	COG2346, Truncated hemoglobins
BC1002_RS06860	COG1959	2 iron, 2 sulfur cluster binding
BC1002_RS06865	COG0542	response to heat
BC1002_RS06870	COG3753	Protein conserved in bacteria
BC1002_RS06880	COG0534	Mate efflux family protein
BC1002_RS06890	COG0254	rRNA binding
BC1002_RS06895	COG3228	Belongs to the MtfA family
BC1002_RS06900	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BC1002_RS06910	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BC1002_RS06915	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BC1002_RS06920	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BC1002_RS06925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC1002_RS06940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC1002_RS06955	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BC1002_RS06960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BC1002_RS06960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BC1002_RS06980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BC1002_RS06990	COG0564	pseudouridine synthase activity
BC1002_RS07000	COG3243	poly(R)-hydroxyalkanoic acid synthase
BC1002_RS07005	COG0183	Belongs to the thiolase family
BC1002_RS07010	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS07020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BC1002_RS07025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BC1002_RS07030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC1002_RS07035	COG0183	Belongs to the thiolase family
BC1002_RS07045	COG0626	cystathionine gamma-synthase activity
BC1002_RS07050	COG0560	Phosphoserine phosphatase
BC1002_RS07055	COG2124	cytochrome p450
BC1002_RS07060	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BC1002_RS07075	COG0583	DNA-binding transcription factor activity
BC1002_RS07080	COG0604	alcohol dehydrogenase
BC1002_RS07090	COG0390	transport system, permease component
BC1002_RS07095	COG1122	ATPase activity
BC1002_RS07100	COG2982	Protein involved in outer membrane biogenesis
BC1002_RS07110	COG4251	negative regulation of phosphorylation
BC1002_RS07120	COG5002	protein histidine kinase activity
BC1002_RS07125	COG1970	mechanosensitive ion channel activity
BC1002_RS07140	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BC1002_RS07145	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BC1002_RS07150	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BC1002_RS07155	COG0450	alkyl hydroperoxide reductase
BC1002_RS07210	COG1929	Belongs to the glycerate kinase type-1 family
BC1002_RS07215	COG0544	peptidyl-prolyl cis-trans isomerase activity
BC1002_RS07220	COG0740	serine-type endopeptidase activity
BC1002_RS07225	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BC1002_RS07230	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BC1002_RS07235	COG0776	regulation of translation
BC1002_RS07250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BC1002_RS07265	COG4181	ATPase activity
BC1002_RS07270	COG0166	Belongs to the GPI family
BC1002_RS07285	COG0047	phosphoribosylformylglycinamidine synthase activity
BC1002_RS07285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BC1002_RS07290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BC1002_RS07300	COG2917	probably involved in intracellular septation
BC1002_RS07305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC1002_RS07310	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BC1002_RS07315	COG0318	PFAM AMP-dependent synthetase and ligase
BC1002_RS07320	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC1002_RS07320	COG1024	Enoyl-CoA hydratase
BC1002_RS07325	COG0183	Belongs to the thiolase family
BC1002_RS07340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC1002_RS07350	COG2130	NADP-dependent
BC1002_RS07370	COG0354	folic acid binding
BC1002_RS07375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BC1002_RS07380	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BC1002_RS07390	COG1247	-acetyltransferase
BC1002_RS07395	COG0084	hydrolase, TatD family'
BC1002_RS07410	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BC1002_RS07410	COG3264	Mechanosensitive ion channel
BC1002_RS07415	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BC1002_RS07420	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS07455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC1002_RS07465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BC1002_RS07475	COG0489	protein tyrosine kinase activity
BC1002_RS07475	COG3206	protein involved in exopolysaccharide biosynthesis
BC1002_RS07495	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS07500	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS07505	COG0643	Histidine kinase
BC1002_RS07505	COG2198	Histidine kinase
BC1002_RS07525	COG0745	RESPONSE REGULATOR receiver
BC1002_RS07530	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BC1002_RS07580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC1002_RS07585	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BC1002_RS07590	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BC1002_RS07595	COG3217	Mosc domain protein beta barrel domain protein
BC1002_RS07595	COG0633	Ferredoxin
BC1002_RS07605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC1002_RS07610	COG2146	nitrite reductase [NAD(P)H] activity
BC1002_RS07615	COG0243	molybdopterin cofactor binding
BC1002_RS07620	COG2223	nitrite transmembrane transporter activity
BC1002_RS07640	COG4106	trans-aconitate 2-methyltransferase activity
BC1002_RS07645	COG0583	DNA-binding transcription factor activity
BC1002_RS07650	COG0625	glutathione transferase activity
BC1002_RS07660	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BC1002_RS07665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC1002_RS07685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BC1002_RS07700	COG2197	response regulator
BC1002_RS07725	COG1566	PFAM secretion protein HlyD family protein
BC1002_RS07735	COG1846	Transcriptional regulator
BC1002_RS07740	COG2814	Major facilitator Superfamily
BC1002_RS07745	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS07755	COG2070	2-Nitropropane dioxygenase
BC1002_RS07780	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BC1002_RS07830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BC1002_RS07915	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BC1002_RS07920	COG4974	Belongs to the 'phage' integrase family
BC1002_RS07935	COG0443	Heat shock 70 kDa protein
BC1002_RS07940	COG0443	Heat shock 70 kDa protein
BC1002_RS07975	COG0739	heme binding
BC1002_RS07975	COG1196	nuclear chromosome segregation
BC1002_RS07975	COG0741	lytic transglycosylase activity
BC1002_RS07980	COG3706	GGDEF domain
BC1002_RS07980	COG4251	negative regulation of phosphorylation
BC1002_RS07980	COG5001	Diguanylate cyclase
BC1002_RS07980	COG2203	Gaf domain
BC1002_RS07985	COG0137	argininosuccinate synthase activity
BC1002_RS07995	COG0583	DNA-binding transcription factor activity
BC1002_RS08000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC1002_RS08005	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BC1002_RS08015	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS08055	COG0642	Histidine kinase
BC1002_RS08085	COG0642	Histidine kinase
BC1002_RS08115	COG1278	Cold shock
BC1002_RS08135	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BC1002_RS08140	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS08145	COG1414	Transcriptional regulator
BC1002_RS08185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BC1002_RS08195	COG0392	lysyltransferase activity
BC1002_RS08195	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BC1002_RS08200	COG0477	Major facilitator Superfamily
BC1002_RS08225	COG2205	protein histidine kinase activity
BC1002_RS08235	COG0492	ferredoxin-NADP+ reductase activity
BC1002_RS08240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC1002_RS08245	COG0583	DNA-binding transcription factor activity
BC1002_RS08255	COG0583	DNA-binding transcription factor activity
BC1002_RS08275	COG0477	Major facilitator Superfamily
BC1002_RS08280	COG2719	SpoVR family
BC1002_RS08285	COG2718	Belongs to the UPF0229 family
BC1002_RS08290	COG2766	serine protein kinase
BC1002_RS08295	COG3971	2-oxopent-4-enoate hydratase activity
BC1002_RS08305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC1002_RS08310	COG1609	Transcriptional regulator
BC1002_RS08315	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS08320	COG1129	ABC transporter
BC1002_RS08325	COG1879	ABC-type sugar transport system periplasmic component
BC1002_RS08335	COG0598	Magnesium transport protein CorA
BC1002_RS08355	COG0039	L-malate dehydrogenase activity
BC1002_RS08385	COG1609	Transcriptional regulator
BC1002_RS08390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC1002_RS08400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC1002_RS08415	COG2855	membrane
BC1002_RS08425	COG0038	chloride channel
BC1002_RS08445	COG0583	DNA-binding transcription factor activity
BC1002_RS08465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC1002_RS08500	COG2072	flavoprotein involved in K transport
BC1002_RS08505	COG1177	transmembrane transport
BC1002_RS08510	COG1176	ABC-type spermidine putrescine transport system, permease component I
BC1002_RS08515	COG3842	ATPase activity
BC1002_RS08525	COG1914	H( )-stimulated, divalent metal cation uptake system
BC1002_RS08540	COG0488	(ABC) transporter
BC1002_RS08545	COG2084	Dehydrogenase
BC1002_RS08550	COG3360	Dodecin
BC1002_RS08560	COG1079	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS08565	COG4603	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS08570	COG3845	ABC transporter
BC1002_RS08610	COG4266	Belongs to the allantoicase family
BC1002_RS08615	COG3195	allantoin biosynthetic process
BC1002_RS08615	COG3648	Uricase
BC1002_RS08630	COG1953	Uracil, thiamine, allantoin
BC1002_RS08635	COG1802	Transcriptional regulator
BC1002_RS08640	COG1619	proteins homologs of microcin C7 resistance protein MccF
BC1002_RS08645	COG0590	tRNA wobble adenosine to inosine editing
BC1002_RS08665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BC1002_RS08665	COG0519	Catalyzes the synthesis of GMP from XMP
BC1002_RS08680	COG0697	spore germination
BC1002_RS08685	COG2914	Belongs to the UPF0125 (RnfH) family
BC1002_RS08690	COG2867	negative regulation of translational initiation
BC1002_RS08695	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BC1002_RS08700	COG0330	HflC and HflK could
BC1002_RS08715	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BC1002_RS08720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC1002_RS08725	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BC1002_RS08730	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BC1002_RS08735	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BC1002_RS08745	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BC1002_RS08750	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BC1002_RS08760	COG0750	zinc metalloprotease
BC1002_RS08765	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BC1002_RS08775	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BC1002_RS08780	COG0233	cytoplasmic translational termination
BC1002_RS08785	COG0528	UMP kinase activity
BC1002_RS08790	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BC1002_RS08795	COG0052	Belongs to the universal ribosomal protein uS2 family
BC1002_RS08800	COG0024	Methionine aminopeptidase
BC1002_RS08815	COG1187	pseudouridine synthase activity
BC1002_RS08820	COG0242	peptide deformylase activity
BC1002_RS08825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BC1002_RS08850	COG2171	N-acyltransferase activity
BC1002_RS08855	COG1393	Belongs to the ArsC family
BC1002_RS08860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC1002_RS08865	COG2890	protein-(glutamine-N5) methyltransferase activity
BC1002_RS08875	COG0386	Belongs to the glutathione peroxidase family
BC1002_RS08880	COG0488	(ABC) transporter
BC1002_RS08885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC1002_RS08900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BC1002_RS08905	COG0477	Major facilitator Superfamily
BC1002_RS08910	COG0351	phosphomethylpyrimidine kinase
BC1002_RS08920	COG1573	uracil-dna glycosylase
BC1002_RS08930	COG1214	PFAM Peptidase M22, glycoprotease
BC1002_RS08940	COG0513	Belongs to the DEAD box helicase family
BC1002_RS08945	COG2224	Isocitrate lyase
BC1002_RS08960	COG0583	DNA-binding transcription factor activity
BC1002_RS08970	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BC1002_RS08985	COG0456	acetyltransferase
BC1002_RS09015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BC1002_RS09020	COG1752	Esterase of the alpha-beta hydrolase superfamily
BC1002_RS09025	COG0791	NLP P60 protein
BC1002_RS09030	COG4172	Belongs to the ABC transporter superfamily
BC1002_RS09035	COG4239	(ABC) transporter, permease
BC1002_RS09040	COG4174	ABC transporter (Permease)
BC1002_RS09045	COG4166	transmembrane transport
BC1002_RS09065	COG0527	aspartate kinase activity
BC1002_RS09070	COG0037	tRNA processing
BC1002_RS09075	COG0825	malonyl-CoA metabolic process
BC1002_RS09085	COG0215	cysteine-tRNA ligase activity
BC1002_RS09095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BC1002_RS09105	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BC1002_RS09110	COG1045	serine acetyltransferase
BC1002_RS09120	COG0483	inositol monophosphate 1-phosphatase activity
BC1002_RS09125	COG0477	Major facilitator Superfamily
BC1002_RS09130	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BC1002_RS09145	COG2850	peptidyl-arginine hydroxylation
BC1002_RS09155	COG1199	ATP-dependent helicase activity
BC1002_RS09170	COG2183	response to ionizing radiation
BC1002_RS09175	COG3158	transport of potassium into the cell
BC1002_RS09180	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BC1002_RS09185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BC1002_RS09190	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BC1002_RS09205	COG0330	HflC and HflK could
BC1002_RS09210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BC1002_RS09215	COG1923	regulation of RNA biosynthetic process
BC1002_RS09220	COG1160	GTP binding
BC1002_RS09225	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BC1002_RS09235	COG0124	histidyl-tRNA synthetase
BC1002_RS09240	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BC1002_RS09250	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BC1002_RS09255	COG0105	UTP biosynthetic process
BC1002_RS09260	COG0670	Belongs to the BI1 family
BC1002_RS09265	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BC1002_RS09270	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BC1002_RS09275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC1002_RS09285	COG0180	Tryptophanyl-tRNA synthetase
BC1002_RS09290	COG1994	Peptidase M50
BC1002_RS09295	COG0009	L-threonylcarbamoyladenylate synthase
BC1002_RS09300	COG0613	PHP domain protein
BC1002_RS09305	COG0596	Alpha beta hydrolase
BC1002_RS09310	COG2833	Protein of unknown function (DUF455)
BC1002_RS09320	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BC1002_RS09330	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BC1002_RS09335	COG0148	phosphopyruvate hydratase activity
BC1002_RS09340	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BC1002_RS09345	COG0504	CTP synthase activity
BC1002_RS09350	COG2267	carboxylic ester hydrolase activity
BC1002_RS09355	COG2333	competence protein COMEC
BC1002_RS09355	COG0658	competence protein
BC1002_RS09360	COG0084	hydrolase, TatD family'
BC1002_RS09365	COG1136	(ABC) transporter
BC1002_RS09380	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BC1002_RS09390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BC1002_RS09400	COG2975	iron-sulfur cluster assembly
BC1002_RS09410	COG0443	Heat shock 70 kDa protein
BC1002_RS09415	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BC1002_RS09420	COG0316	Belongs to the HesB IscA family
BC1002_RS09425	COG0822	iron-sulfur transferase activity
BC1002_RS09430	COG1104	cysteine desulfurase activity
BC1002_RS09440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BC1002_RS09465	COG1414	Transcriptional regulator
BC1002_RS09480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BC1002_RS09485	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC1002_RS09490	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BC1002_RS09500	COG4566	intracellular signal transduction
BC1002_RS09505	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BC1002_RS09510	COG0339	signal peptide processing
BC1002_RS09515	COG0402	S-adenosylhomocysteine deaminase activity
BC1002_RS09520	COG1794	racemase activity, acting on amino acids and derivatives
BC1002_RS09535	COG1505	serine-type exopeptidase activity
BC1002_RS09545	COG3852	Histidine kinase
BC1002_RS09550	COG0174	glutamine synthetase
BC1002_RS09560	COG1546	Belongs to the CinA family
BC1002_RS09560	COG1058	Belongs to the CinA family
BC1002_RS09585	COG1643	Atp-dependent helicase
BC1002_RS09590	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BC1002_RS09590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BC1002_RS09595	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BC1002_RS09650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC1002_RS09655	COG0243	molybdopterin cofactor binding
BC1002_RS09660	COG1451	nucleotide metabolic process
BC1002_RS09675	COG1609	Transcriptional regulator
BC1002_RS09685	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BC1002_RS09690	COG1177	transmembrane transport
BC1002_RS09695	COG3842	ATPase activity
BC1002_RS09700	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BC1002_RS09705	COG2814	Major facilitator Superfamily
BC1002_RS09715	COG2197	response regulator
BC1002_RS09720	COG2197	response regulator
BC1002_RS09740	COG4585	Histidine kinase
BC1002_RS09755	COG1902	pentaerythritol trinitrate reductase activity
BC1002_RS09755	COG0446	pyridine nucleotide-disulphide oxidoreductase
BC1002_RS09770	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BC1002_RS09775	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BC1002_RS09800	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BC1002_RS09815	COG1620	l-lactate permease
BC1002_RS09825	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BC1002_RS09850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC1002_RS09855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS09875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BC1002_RS09900	COG3511	phospholipase C
BC1002_RS09910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC1002_RS09920	COG0583	DNA-binding transcription factor activity
BC1002_RS09930	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS09935	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS09960	COG0776	regulation of translation
BC1002_RS09970	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BC1002_RS09980	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BC1002_RS09985	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BC1002_RS09990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BC1002_RS10000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BC1002_RS10005	COG0251	oxidation-reduction process
BC1002_RS10025	COG4566	intracellular signal transduction
BC1002_RS10035	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS10045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BC1002_RS10050	COG0477	Major facilitator Superfamily
BC1002_RS10065	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BC1002_RS10075	COG1295	ribonuclease BN
BC1002_RS10090	COG0277	FAD linked oxidase domain protein
BC1002_RS10100	COG0583	DNA-binding transcription factor activity
BC1002_RS10120	COG1566	PFAM secretion protein HlyD family protein
BC1002_RS10140	COG0840	transmembrane signaling receptor activity
BC1002_RS10145	COG2223	nitrite transmembrane transporter activity
BC1002_RS10160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC1002_RS10165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BC1002_RS10170	COG0210	DNA helicase
BC1002_RS10175	COG0525	valine-tRNA ligase activity
BC1002_RS10180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC1002_RS10185	COG0425	Belongs to the sulfur carrier protein TusA family
BC1002_RS10190	COG0673	inositol 2-dehydrogenase activity
BC1002_RS10195	COG0673	inositol 2-dehydrogenase activity
BC1002_RS10210	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS10215	COG1129	ABC transporter
BC1002_RS10225	COG3962	Belongs to the TPP enzyme family
BC1002_RS10235	COG3718	enzyme involved in inositol metabolism
BC1002_RS10245	COG0411	ABC transporter
BC1002_RS10260	COG0824	Thioesterase
BC1002_RS10270	COG2816	NAD+ diphosphatase activity
BC1002_RS10280	COG0477	Major facilitator Superfamily
BC1002_RS10290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BC1002_RS10295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC1002_RS10310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BC1002_RS10315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS10320	COG1051	belongs to the nudix hydrolase family
BC1002_RS10330	COG0840	transmembrane signaling receptor activity
BC1002_RS10340	COG1968	undecaprenyl-diphosphatase activity
BC1002_RS10350	COG4942	peptidase
BC1002_RS10365	COG0534	Mate efflux family protein
BC1002_RS10395	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BC1002_RS10405	COG0745	RESPONSE REGULATOR receiver
BC1002_RS10415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BC1002_RS10420	COG0581	inorganic phosphate transmembrane transporter activity
BC1002_RS10425	COG0573	inorganic phosphate transmembrane transporter activity
BC1002_RS10430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BC1002_RS10435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC1002_RS10440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BC1002_RS10445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BC1002_RS10450	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BC1002_RS10455	COG1534	Rna-binding protein
BC1002_RS10465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BC1002_RS10470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BC1002_RS10475	COG0505	Belongs to the CarA family
BC1002_RS10485	COG0741	lytic transglycosylase activity
BC1002_RS10485	COG1388	LysM domain
BC1002_RS10490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC1002_RS10495	COG2226	methyltransferase
BC1002_RS10500	COG0328	RNA-DNA hybrid ribonuclease activity
BC1002_RS10505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BC1002_RS10515	COG1132	(ABC) transporter
BC1002_RS10530	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS10535	COG1132	(ABC) transporter
BC1002_RS10540	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BC1002_RS10545	COG1877	trehalose-phosphatase activity
BC1002_RS10565	COG2153	protein acetylation
BC1002_RS10570	COG5002	protein histidine kinase activity
BC1002_RS10570	COG5001	Diguanylate cyclase
BC1002_RS10570	COG3447	MASE1 domain protein
BC1002_RS10600	COG0322	excinuclease ABC activity
BC1002_RS10610	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BC1002_RS10615	COG3237	CsbD-like
BC1002_RS10620	COG2204	response regulator
BC1002_RS10630	COG0736	holo-[acyl-carrier-protein] synthase activity
BC1002_RS10635	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BC1002_RS10640	COG1381	Involved in DNA repair and RecF pathway recombination
BC1002_RS10645	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BC1002_RS10650	COG0571	ribonuclease III activity
BC1002_RS10655	COG0681	Belongs to the peptidase S26 family
BC1002_RS10660	COG0481	GTPase activity
BC1002_RS10670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC1002_RS10695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BC1002_RS10715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC1002_RS10720	COG0416	fatty acid biosynthetic process
BC1002_RS10725	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BC1002_RS10730	COG1399	metal-binding, possibly nucleic acid-binding protein
BC1002_RS10735	COG0424	maF-like protein
BC1002_RS10755	COG0546	phosphoglycolate phosphatase activity
BC1002_RS10760	COG0564	pseudouridine synthase activity
BC1002_RS10765	COG1530	ribonuclease E activity
BC1002_RS10770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BC1002_RS10780	COG0303	'Molybdopterin
BC1002_RS10815	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BC1002_RS10830	COG3045	CreA protein
BC1002_RS10840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BC1002_RS10870	COG2501	S4 domain
BC1002_RS10875	COG0534	Mate efflux family protein
BC1002_RS10885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC1002_RS10890	COG0114	fumarate hydratase activity
BC1002_RS10910	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BC1002_RS10955	COG2204	response regulator
BC1002_RS10965	COG0312	modulator of DNA gyrase
BC1002_RS10970	COG3028	Belongs to the UPF0307 family
BC1002_RS10975	COG0521	Mo-molybdopterin cofactor biosynthetic process
BC1002_RS10980	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BC1002_RS10990	COG1162	GTPase activity
BC1002_RS11010	COG0335	large ribosomal subunit rRNA binding
BC1002_RS11015	COG0336	Belongs to the RNA methyltransferase TrmD family
BC1002_RS11020	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BC1002_RS11025	COG0228	four-way junction DNA binding
BC1002_RS11050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC1002_RS11055	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS11080	COG2011	ABC-type metal ion transport system permease component
BC1002_RS11085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BC1002_RS11090	COG2267	carboxylic ester hydrolase activity
BC1002_RS11100	COG0123	including yeast histone deacetylase and acetoin utilization protein
BC1002_RS11105	COG2951	lytic endotransglycosylase activity
BC1002_RS11120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC1002_RS11125	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BC1002_RS11135	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BC1002_RS11145	COG0776	regulation of translation
BC1002_RS11155	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BC1002_RS11170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BC1002_RS11180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BC1002_RS11200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BC1002_RS11205	COG0546	phosphoglycolate phosphatase activity
BC1002_RS11220	COG1910	domain protein
BC1002_RS11235	COG3383	formate dehydrogenase (NAD+) activity
BC1002_RS11270	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BC1002_RS11275	COG4651	solute:proton antiporter activity
BC1002_RS11275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BC1002_RS11280	COG0154	amidase activity
BC1002_RS11285	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BC1002_RS11305	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BC1002_RS11310	COG0402	S-adenosylhomocysteine deaminase activity
BC1002_RS11325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BC1002_RS11330	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS11340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BC1002_RS11360	COG2986	histidine ammonia-lyase
BC1002_RS11380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC1002_RS11400	COG2119	membrane
BC1002_RS11410	COG0308	aminopeptidase N
BC1002_RS11415	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BC1002_RS11440	COG1199	ATP-dependent helicase activity
BC1002_RS11440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BC1002_RS11445	COG1278	Cold shock
BC1002_RS11455	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BC1002_RS11480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BC1002_RS11490	COG0194	GDP metabolic process
BC1002_RS11495	COG1561	YicC-like family, N-terminal region
BC1002_RS11500	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BC1002_RS11505	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BC1002_RS11510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BC1002_RS11535	COG0251	oxidation-reduction process
BC1002_RS11545	COG2814	Major facilitator Superfamily
BC1002_RS11555	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BC1002_RS11560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC1002_RS11560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC1002_RS11570	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BC1002_RS11575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BC1002_RS11620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BC1002_RS11625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BC1002_RS11630	COG0436	Aminotransferase
BC1002_RS11640	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BC1002_RS11670	COG0762	integral membrane protein
BC1002_RS11675	COG0840	transmembrane signaling receptor activity
BC1002_RS11685	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BC1002_RS11690	COG1968	undecaprenyl-diphosphatase activity
BC1002_RS11725	COG1278	Cold shock
BC1002_RS11780	COG2205	protein histidine kinase activity
BC1002_RS11790	COG1309	transcriptional regulator
BC1002_RS11820	COG1113	amino acid transport
BC1002_RS11825	COG0596	Alpha beta hydrolase
BC1002_RS11840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC1002_RS11850	COG0747	negative chemotaxis
BC1002_RS11855	COG4172	Belongs to the ABC transporter superfamily
BC1002_RS11860	COG1446	asparaginase
BC1002_RS11875	COG1187	pseudouridine synthase activity
BC1002_RS11895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BC1002_RS11900	COG0456	acetyltransferase
BC1002_RS11930	COG0683	leucine binding
BC1002_RS11935	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BC1002_RS11940	COG1047	Peptidyl-prolyl cis-trans
BC1002_RS11945	COG2003	Belongs to the UPF0758 family
BC1002_RS11950	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BC1002_RS11955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BC1002_RS11960	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BC1002_RS11970	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BC1002_RS11980	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BC1002_RS11980	COG3264	Mechanosensitive ion channel
BC1002_RS11985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BC1002_RS11985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BC1002_RS11990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BC1002_RS11995	COG0196	riboflavin kinase activity
BC1002_RS12000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BC1002_RS12005	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BC1002_RS12010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BC1002_RS12015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC1002_RS12020	COG0756	dUTP diphosphatase activity
BC1002_RS12025	COG0542	response to heat
BC1002_RS12030	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BC1002_RS12035	COG1278	Cold shock
BC1002_RS12055	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BC1002_RS12065	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BC1002_RS12100	COG2197	response regulator
BC1002_RS12125	COG1181	Belongs to the D-alanine--D-alanine ligase family
BC1002_RS12135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BC1002_RS12170	COG0747	negative chemotaxis
BC1002_RS12175	COG0601	transmembrane transport
BC1002_RS12180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC1002_RS12200	COG0656	L-ascorbic acid biosynthetic process
BC1002_RS12205	COG2188	Transcriptional regulator
BC1002_RS12230	COG2814	Major facilitator Superfamily
BC1002_RS12240	COG1595	DNA-templated transcription, initiation
BC1002_RS12245	COG0740	serine-type endopeptidase activity
BC1002_RS12265	COG1570	exodeoxyribonuclease VII activity
BC1002_RS12270	COG1663	tetraacyldisaccharide 4'-kinase activity
BC1002_RS12275	COG2835	tetraacyldisaccharide 4'-kinase activity
BC1002_RS12280	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BC1002_RS12285	COG0563	adenylate kinase activity
BC1002_RS12300	COG0728	peptidoglycan biosynthetic process
BC1002_RS12305	COG0268	Binds directly to 16S ribosomal RNA
BC1002_RS12315	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BC1002_RS12320	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BC1002_RS12325	COG1666	GTP binding
BC1002_RS12330	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BC1002_RS12335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BC1002_RS12340	COG0318	PFAM AMP-dependent synthetase and ligase
BC1002_RS12345	COG4974	Belongs to the 'phage' integrase family
BC1002_RS12350	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC1002_RS12355	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BC1002_RS12360	COG0802	atpase or kinase
BC1002_RS12365	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC1002_RS12375	COG1741	Belongs to the pirin family
BC1002_RS12385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BC1002_RS12390	COG0259	pyridoxamine-phosphate oxidase activity
BC1002_RS12395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BC1002_RS12405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC1002_RS12410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BC1002_RS12415	COG1522	sequence-specific DNA binding
BC1002_RS12420	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BC1002_RS12430	COG3483	tryptophan 2,3-dioxygenase activity
BC1002_RS12450	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS12455	COG1070	Carbohydrate kinase
BC1002_RS12460	COG1063	alcohol dehydrogenase
BC1002_RS12465	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS12475	COG1879	ABC-type sugar transport system periplasmic component
BC1002_RS12485	COG0246	Mannitol dehydrogenase
BC1002_RS12490	COG1070	Carbohydrate kinase
BC1002_RS12495	COG2390	Transcriptional regulator
BC1002_RS12505	COG3842	ATPase activity
BC1002_RS12520	COG1175	transmembrane transport
BC1002_RS12535	COG0735	belongs to the Fur family
BC1002_RS12540	COG0803	Belongs to the bacterial solute-binding protein 9 family
BC1002_RS12545	COG1121	(ABC) transporter
BC1002_RS12550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BC1002_RS12555	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BC1002_RS12565	COG1070	Carbohydrate kinase
BC1002_RS12570	COG2233	PERMEase
BC1002_RS12580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC1002_RS12585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BC1002_RS12595	COG1335	isochorismatase
BC1002_RS12600	COG4977	sequence-specific DNA binding
BC1002_RS12620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC1002_RS12625	COG0642	Histidine kinase
BC1002_RS12650	COG0009	L-threonylcarbamoyladenylate synthase
BC1002_RS12655	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BC1002_RS12660	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BC1002_RS12665	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BC1002_RS12675	COG0469	pyruvate kinase activity
BC1002_RS12680	COG0126	phosphoglycerate kinase activity
BC1002_RS12705	COG0859	PFAM glycosyl transferase family 9
BC1002_RS12715	COG0429	hydrolase of the alpha beta-hydrolase fold
BC1002_RS12730	COG0315	cyclic pyranopterin monophosphate synthase activity
BC1002_RS12745	COG4969	Belongs to the N-Me-Phe pilin family
BC1002_RS12750	COG0861	Integral membrane protein TerC family
BC1002_RS12755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BC1002_RS12760	COG0045	succinate-CoA ligase (ADP-forming) activity
BC1002_RS12770	COG2137	regulation of response to DNA damage stimulus
BC1002_RS12775	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BC1002_RS12790	COG0477	Major facilitator Superfamily
BC1002_RS12800	COG2814	Major facilitator Superfamily
BC1002_RS12830	COG4770	biotin carboxylase activity
BC1002_RS12845	COG1846	Transcriptional regulator
BC1002_RS12850	COG2814	Major facilitator Superfamily
BC1002_RS12855	COG2186	Transcriptional regulator
BC1002_RS12860	COG4948	Mandelate Racemase Muconate Lactonizing
BC1002_RS12890	COG1272	protein, Hemolysin III
BC1002_RS12895	COG0513	Belongs to the DEAD box helicase family
BC1002_RS12945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BC1002_RS12950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC1002_RS12960	COG1396	sequence-specific DNA binding
BC1002_RS12965	COG2814	Major facilitator Superfamily
BC1002_RS12975	COG0583	DNA-binding transcription factor activity
BC1002_RS12980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BC1002_RS12985	COG1702	phosphate starvation-inducible protein PhoH
BC1002_RS12990	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BC1002_RS12995	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BC1002_RS13000	COG4535	Mg2 and Co2 transporter CorC
BC1002_RS13005	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BC1002_RS13010	COG0625	glutathione transferase activity
BC1002_RS13015	COG0006	proline dipeptidase activity
BC1002_RS13020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC1002_RS13025	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BC1002_RS13030	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BC1002_RS13035	COG0138	bifunctional purine biosynthesis protein purh
BC1002_RS13045	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BC1002_RS13050	COG0632	four-way junction helicase activity
BC1002_RS13055	COG2255	four-way junction helicase activity
BC1002_RS13070	COG1490	D-aminoacyl-tRNA deacylase activity
BC1002_RS13080	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BC1002_RS13090	COG0316	Belongs to the HesB IscA family
BC1002_RS13095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BC1002_RS13100	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BC1002_RS13115	COG0418	dihydroorotase activity
BC1002_RS13120	COG0121	glutamine amidotransferase
BC1002_RS13125	COG1126	abc transporter atp-binding protein
BC1002_RS13130	COG0765	amino acid transport
BC1002_RS13135	COG0765	amino acid transport
BC1002_RS13145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BC1002_RS13150	COG0583	DNA-binding transcription factor activity
BC1002_RS13160	COG3265	gluconokinase activity
BC1002_RS13170	COG0800	Aldolase
BC1002_RS13185	COG1981	membrane
BC1002_RS13190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BC1002_RS13205	COG0495	leucyl-tRNA aminoacylation
BC1002_RS13220	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BC1002_RS13225	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BC1002_RS13230	COG0735	belongs to the Fur family
BC1002_RS13235	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BC1002_RS13240	COG4266	Belongs to the allantoicase family
BC1002_RS13255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BC1002_RS13260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BC1002_RS13275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BC1002_RS13280	COG2732	(Barnase) inhibitor
BC1002_RS13285	COG4290	ribonuclease
BC1002_RS13300	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BC1002_RS13305	COG1546	Belongs to the CinA family
BC1002_RS13315	COG0284	orotidine-5'-phosphate decarboxylase activity
BC1002_RS13340	COG1129	ABC transporter
BC1002_RS13350	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS13355	COG0800	Aldolase
BC1002_RS13360	COG3734	2-keto-3-deoxy-galactonokinase
BC1002_RS13365	COG1414	Transcriptional regulator
BC1002_RS13370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC1002_RS13375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BC1002_RS13380	COG0557	exoribonuclease II activity
BC1002_RS13385	COG3150	esterase
BC1002_RS13390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BC1002_RS13400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC1002_RS13405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BC1002_RS13410	COG0511	ligase activity, forming carbon-carbon bonds
BC1002_RS13415	COG0439	Biotin carboxylase
BC1002_RS13420	COG2264	protein methyltransferase activity
BC1002_RS13430	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BC1002_RS13435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC1002_RS13450	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC1002_RS13470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BC1002_RS13475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BC1002_RS13480	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BC1002_RS13485	COG2095	MarC family integral membrane protein
BC1002_RS13490	COG0442	prolyl-tRNA aminoacylation
BC1002_RS13495	COG0494	nUDIX hydrolase
BC1002_RS13505	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BC1002_RS13510	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BC1002_RS13520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BC1002_RS13525	COG0142	geranyltranstransferase activity
BC1002_RS13535	COG4536	flavin adenine dinucleotide binding
BC1002_RS13560	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BC1002_RS13565	COG0494	nUDIX hydrolase
BC1002_RS13580	COG0653	protein targeting
BC1002_RS13595	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BC1002_RS13600	COG0678	peroxiredoxin activity
BC1002_RS13615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BC1002_RS13620	COG1181	Belongs to the D-alanine--D-alanine ligase family
BC1002_RS13625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BC1002_RS13630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BC1002_RS13640	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BC1002_RS13645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BC1002_RS13650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BC1002_RS13655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BC1002_RS13665	COG3116	cell division
BC1002_RS13670	COG0275	rRNA processing
BC1002_RS13675	COG2001	Belongs to the MraZ family
BC1002_RS13680	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BC1002_RS13685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BC1002_RS13690	COG0318	PFAM AMP-dependent synthetase and ligase
BC1002_RS13700	COG0243	molybdopterin cofactor binding
BC1002_RS13705	COG1473	amidohydrolase
BC1002_RS13735	COG1024	Enoyl-CoA hydratase
BC1002_RS13745	COG1024	Enoyl-CoA hydratase
BC1002_RS13760	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BC1002_RS13770	COG2967	ApaG domain
BC1002_RS13775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BC1002_RS13780	COG0546	phosphoglycolate phosphatase activity
BC1002_RS13795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BC1002_RS13800	COG0134	indole-3-glycerol-phosphate synthase activity
BC1002_RS13810	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BC1002_RS13815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BC1002_RS13825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BC1002_RS13830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC1002_RS13840	COG0012	GTP binding
BC1002_RS13860	COG0395	ABC-type sugar transport system, permease component
BC1002_RS13865	COG3842	ATPase activity
BC1002_RS13870	COG0488	(ABC) transporter
BC1002_RS13895	COG0745	RESPONSE REGULATOR receiver
BC1002_RS13900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BC1002_RS13905	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BC1002_RS13910	COG2890	protein-(glutamine-N5) methyltransferase activity
BC1002_RS13915	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BC1002_RS13925	COG3384	dioxygenase
BC1002_RS13930	COG0531	amino acid
BC1002_RS13935	COG1278	Cold shock
BC1002_RS13940	COG0443	Heat shock 70 kDa protein
BC1002_RS13945	COG2271	Major facilitator Superfamily
BC1002_RS14015	COG2969	positive regulation of protein catabolic process
BC1002_RS14020	COG0625	glutathione transferase activity
BC1002_RS14025	COG2857	Cytochrome c1
BC1002_RS14030	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BC1002_RS14035	COG0723	plastoquinol--plastocyanin reductase activity
BC1002_RS14040	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BC1002_RS14045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC1002_RS14050	COG0805	protein transport
BC1002_RS14055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BC1002_RS14060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BC1002_RS14075	COG0140	phosphoribosyl-ATP diphosphatase activity
BC1002_RS14085	COG0107	imidazoleglycerol-phosphate synthase activity
BC1002_RS14090	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BC1002_RS14100	COG0131	Imidazoleglycerol-phosphate dehydratase
BC1002_RS14120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BC1002_RS14130	COG0842	Transport permease protein
BC1002_RS14135	COG1131	(ABC) transporter
BC1002_RS14155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BC1002_RS14160	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BC1002_RS14165	COG1127	ABC transporter
BC1002_RS14190	COG4178	(ABC) transporter
BC1002_RS14210	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BC1002_RS14240	COG2365	Tyrosine phosphatase family
BC1002_RS14250	COG0067	glutamate synthase
BC1002_RS14250	COG0070	glutamate synthase
BC1002_RS14250	COG0069	glutamate synthase activity
BC1002_RS14270	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BC1002_RS14275	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BC1002_RS14310	COG1965	Belongs to the frataxin family
BC1002_RS14325	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BC1002_RS14330	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BC1002_RS14335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BC1002_RS14340	COG1333	cytochrome c biogenesis protein
BC1002_RS14350	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BC1002_RS14360	COG4232	protein-disulfide reductase activity
BC1002_RS14370	COG0203	ribosomal protein L17
BC1002_RS14375	COG0202	RNA polymerase activity
BC1002_RS14380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BC1002_RS14385	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BC1002_RS14390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BC1002_RS14400	COG0201	protein transport
BC1002_RS14405	COG0200	Binds to the 23S rRNA
BC1002_RS14410	COG1841	ribosomal large subunit assembly
BC1002_RS14420	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BC1002_RS14425	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BC1002_RS14430	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BC1002_RS14435	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BC1002_RS14440	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BC1002_RS14445	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BC1002_RS14450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BC1002_RS14455	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BC1002_RS14460	COG0255	Belongs to the universal ribosomal protein uL29 family
BC1002_RS14465	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BC1002_RS14470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BC1002_RS14475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BC1002_RS14480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BC1002_RS14485	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BC1002_RS14490	COG0089	rRNA binding
BC1002_RS14495	COG0088	Forms part of the polypeptide exit tunnel
BC1002_RS14500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BC1002_RS14505	COG0051	transcription antitermination factor activity, RNA binding
BC1002_RS14510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BC1002_RS14515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BC1002_RS14520	COG0049	tRNA binding
BC1002_RS14525	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BC1002_RS14530	COG0514	ATP-dependent DNA helicase (RecQ)
BC1002_RS14535	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BC1002_RS14540	COG0085	RNA polymerase activity
BC1002_RS14545	COG0222	ribosome binding
BC1002_RS14550	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BC1002_RS14555	COG0081	regulation of translation
BC1002_RS14560	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BC1002_RS14570	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BC1002_RS14580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BC1002_RS14630	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BC1002_RS14635	COG3396	Phenylacetate-CoA oxygenase
BC1002_RS14640	COG3460	Phenylacetate-CoA oxygenase
BC1002_RS14645	COG3396	Phenylacetate-CoA oxygenase
BC1002_RS14650	COG2151	metal-sulfur cluster biosynthetic enzyme
BC1002_RS14655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BC1002_RS14675	COG1522	sequence-specific DNA binding
BC1002_RS14695	COG0281	malic enzyme
BC1002_RS14695	COG0280	phosphate acetyltransferase
BC1002_RS14700	COG2814	Major facilitator Superfamily
BC1002_RS14705	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BC1002_RS14710	COG2197	response regulator
BC1002_RS14715	COG1881	PFAM PEBP family protein
BC1002_RS14725	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BC1002_RS14730	COG1280	lysine exporter protein (LysE YggA)
BC1002_RS14735	COG2084	Dehydrogenase
BC1002_RS14755	COG1414	Transcriptional regulator
BC1002_RS14790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BC1002_RS14795	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BC1002_RS14800	COG0037	tRNA processing
BC1002_RS14810	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS14825	COG0617	tRNA 3'-terminal CCA addition
BC1002_RS14845	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BC1002_RS14855	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BC1002_RS14860	COG1984	allophanate hydrolase subunit 2
BC1002_RS14865	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BC1002_RS14885	COG4608	Belongs to the ABC transporter superfamily
BC1002_RS14890	COG0444	Belongs to the ABC transporter superfamily
BC1002_RS14895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC1002_RS14900	COG0601	transmembrane transport
BC1002_RS14905	COG0747	negative chemotaxis
BC1002_RS14910	COG0747	negative chemotaxis
BC1002_RS14915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BC1002_RS14920	COG1950	PFAM Membrane protein of
BC1002_RS14925	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BC1002_RS14930	COG1346	cytolysis
BC1002_RS14935	COG1380	Effector of murein hydrolase LrgA
BC1002_RS14940	COG0583	DNA-binding transcription factor activity
BC1002_RS14950	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS14985	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BC1002_RS15095	COG0582	viral genome integration into host DNA
BC1002_RS15100	COG1580	Controls the rotational direction of flagella during chemotaxis
BC1002_RS15110	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC1002_RS15125	COG1987	bacterial-type flagellum assembly
BC1002_RS15140	COG1256	bacterial-type flagellum assembly
BC1002_RS15145	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BC1002_RS15155	COG1706	bacterial-type flagellum-dependent cell motility
BC1002_RS15160	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BC1002_RS15165	COG4786	Flagellar basal body rod
BC1002_RS15185	COG1558	bacterial-type flagellum-dependent cell motility
BC1002_RS15190	COG1815	bacterial-type flagellum-dependent cell motility
BC1002_RS15200	COG2747	anti-sigma28 factor FlgM
BC1002_RS15215	COG1191	sigma factor activity
BC1002_RS15235	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BC1002_RS15250	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BC1002_RS15255	COG0745	RESPONSE REGULATOR receiver
BC1002_RS15260	COG2201	protein-glutamate methylesterase activity
BC1002_RS15265	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BC1002_RS15275	COG0840	transmembrane signaling receptor activity
BC1002_RS15290	COG2201	protein-glutamate methylesterase activity
BC1002_RS15295	COG1360	Flagellar Motor Protein
BC1002_RS15315	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS15325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BC1002_RS15350	COG2818	Glycosylase
BC1002_RS15360	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BC1002_RS15365	COG0667	Aldo Keto reductase
BC1002_RS15395	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS15400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC1002_RS15435	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BC1002_RS15450	COG3245	cytochrome
BC1002_RS15455	COG0210	DNA helicase
BC1002_RS15460	COG0673	inositol 2-dehydrogenase activity
BC1002_RS15470	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BC1002_RS15475	COG0509	glycine decarboxylation via glycine cleavage system
BC1002_RS15480	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BC1002_RS15480	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BC1002_RS15490	COG1760	l-serine dehydratase
BC1002_RS15495	COG0028	Belongs to the TPP enzyme family
BC1002_RS15505	COG0506	proline dehydrogenase activity
BC1002_RS15505	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BC1002_RS15505	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BC1002_RS15515	COG2855	membrane
BC1002_RS15520	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BC1002_RS15525	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BC1002_RS15535	COG0318	PFAM AMP-dependent synthetase and ligase
BC1002_RS15540	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BC1002_RS15545	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BC1002_RS15550	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BC1002_RS15555	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BC1002_RS15560	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BC1002_RS15565	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BC1002_RS15575	COG0356	it plays a direct role in the translocation of protons across the membrane
BC1002_RS15585	COG1475	DNA binding
BC1002_RS15590	COG1192	Involved in chromosome partitioning
BC1002_RS15595	COG0357	Ribosomal RNA small subunit methyltransferase G
BC1002_RS15600	COG0445	tRNA wobble uridine modification
BC1002_RS15635	COG0559	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS15655	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BC1002_RS15665	COG0583	DNA-binding transcription factor activity
BC1002_RS15675	COG1522	sequence-specific DNA binding
BC1002_RS15680	COG3186	Phenylalanine-4-hydroxylase
BC1002_RS15685	COG2154	pterin-4-alpha-carbinolamine dehydratase
BC1002_RS15710	COG1902	pentaerythritol trinitrate reductase activity
BC1002_RS15715	COG0505	Belongs to the CarA family
BC1002_RS15725	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BC1002_RS15735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC1002_RS15735	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BC1002_RS15745	COG0523	cobalamin synthesis protein
BC1002_RS15765	COG1459	type II secretion system
BC1002_RS15825	COG1846	Transcriptional regulator
BC1002_RS15830	COG2814	Major facilitator Superfamily
BC1002_RS15850	COG2169	Transcriptional regulator
BC1002_RS15850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC1002_RS15870	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS15900	COG0537	adenosine 5'-monophosphoramidase activity
BC1002_RS15910	COG4221	oxidoreductase activity
BC1002_RS15915	COG5001	Diguanylate cyclase
BC1002_RS15915	COG3706	GGDEF domain
BC1002_RS15915	COG4251	negative regulation of phosphorylation
BC1002_RS15915	COG2203	Gaf domain
BC1002_RS15935	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BC1002_RS15945	COG0706	membrane insertase activity
BC1002_RS15950	COG0594	ribonuclease P activity
BC1002_RS15990	COG2197	response regulator
BC1002_RS15995	COG0535	radical SAM domain protein
BC1002_RS16005	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BC1002_RS16010	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BC1002_RS16020	COG3038	cytochrome b561
BC1002_RS16030	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
BC1002_RS16035	COG1229	Formylmethanofuran dehydrogenase subunit A
BC1002_RS16075	COG1850	ribulose-bisphosphate carboxylase activity
BC1002_RS16090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BC1002_RS16095	COG3954	Phosphoribulokinase
BC1002_RS16100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BC1002_RS16105	COG0191	fructose-bisphosphate aldolase activity
BC1002_RS16110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BC1002_RS16125	COG3284	Transcriptional regulator
BC1002_RS16130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BC1002_RS16140	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
BC1002_RS16150	COG0189	ligase activity
BC1002_RS16155	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
BC1002_RS16165	COG0702	epimerase
BC1002_RS16175	COG2154	pterin-4-alpha-carbinolamine dehydratase
BC1002_RS16185	COG2010	Cytochrome c
BC1002_RS16200	COG0583	DNA-binding transcription factor activity
BC1002_RS16205	COG0714	Associated with various cellular activities
BC1002_RS16240	COG4977	sequence-specific DNA binding
BC1002_RS16295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC1002_RS16300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC1002_RS16305	COG4521	taurine ABC transporter
BC1002_RS16310	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BC1002_RS16315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC1002_RS16320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS16330	COG0765	amino acid transport
BC1002_RS16335	COG3608	succinylglutamate desuccinylase aspartoacylase
BC1002_RS16340	COG2079	MmgE PrpD family protein
BC1002_RS16350	COG1063	alcohol dehydrogenase
BC1002_RS16365	COG2188	Transcriptional regulator
BC1002_RS16370	COG2814	Major facilitator Superfamily
BC1002_RS16380	COG0583	DNA-binding transcription factor activity
BC1002_RS16405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS16410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC1002_RS16415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC1002_RS16435	COG2175	clavaminate synthase activity
BC1002_RS16445	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BC1002_RS16450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC1002_RS16480	COG0604	alcohol dehydrogenase
BC1002_RS16505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BC1002_RS16510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BC1002_RS16535	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS16540	COG1283	sodium-dependent phosphate transmembrane transporter activity
BC1002_RS16575	COG2159	amidohydrolase
BC1002_RS16600	COG0489	protein tyrosine kinase activity
BC1002_RS16600	COG3206	protein involved in exopolysaccharide biosynthesis
BC1002_RS16625	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS16635	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BC1002_RS16635	COG0662	Cupin 2, conserved barrel domain protein
BC1002_RS16680	COG2814	Major facilitator Superfamily
BC1002_RS16725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BC1002_RS16755	COG1064	alcohol dehydrogenase
BC1002_RS16760	COG4181	ATPase activity
BC1002_RS16765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BC1002_RS16770	COG1053	succinate dehydrogenase
BC1002_RS16775	COG1053	succinate dehydrogenase
BC1002_RS16790	COG2814	Major facilitator Superfamily
BC1002_RS16795	COG1414	Transcriptional regulator
BC1002_RS16805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BC1002_RS16825	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BC1002_RS16840	COG5002	protein histidine kinase activity
BC1002_RS16845	COG1131	(ABC) transporter
BC1002_RS16850	COG0842	Transport permease protein
BC1002_RS16860	COG1917	Cupin 2, conserved barrel domain protein
BC1002_RS16860	COG4977	sequence-specific DNA binding
BC1002_RS16880	COG2223	nitrite transmembrane transporter activity
BC1002_RS16895	COG1802	Transcriptional regulator
BC1002_RS16905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC1002_RS16910	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC1002_RS16935	COG0583	DNA-binding transcription factor activity
BC1002_RS16940	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS16945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC1002_RS16960	COG1739	Uncharacterized protein family UPF0029
BC1002_RS16985	COG0840	transmembrane signaling receptor activity
BC1002_RS16990	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BC1002_RS16995	COG0028	Belongs to the TPP enzyme family
BC1002_RS16995	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BC1002_RS17000	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BC1002_RS17010	COG0318	PFAM AMP-dependent synthetase and ligase
BC1002_RS17020	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BC1002_RS17025	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BC1002_RS17030	COG2080	2 iron, 2 sulfur cluster binding
BC1002_RS17035	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC1002_RS17040	COG0649	NAD binding
BC1002_RS17045	COG0651	ATP synthesis coupled electron transport
BC1002_RS17055	COG0650	Formate hydrogenlyase subunit 4
BC1002_RS17060	COG0651	ATP synthesis coupled electron transport
BC1002_RS17075	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BC1002_RS17080	COG2824	Alkylphosphonate utilization operon protein PhnA
BC1002_RS17100	COG1360	Flagellar Motor Protein
BC1002_RS17120	COG0726	polysaccharide deacetylase
BC1002_RS17125	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS17150	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BC1002_RS17175	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BC1002_RS17180	COG2814	Major facilitator Superfamily
BC1002_RS17190	COG0058	SHG alpha-glucan phosphorylase activity
BC1002_RS17200	COG0786	glutamate:sodium symporter activity
BC1002_RS17205	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BC1002_RS17220	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS17235	COG2030	dehydratase
BC1002_RS17240	COG3243	poly(R)-hydroxyalkanoic acid synthase
BC1002_RS17250	COG3246	L-lysine catabolic process to acetate
BC1002_RS17265	COG2175	clavaminate synthase activity
BC1002_RS17330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BC1002_RS17355	COG3454	Phosphonate metabolism
BC1002_RS17360	COG4778	phosphonate C-P lyase system protein PhnL
BC1002_RS17365	COG4107	phosphonate C-P lyase system protein PhnK
BC1002_RS17370	COG3627	carbon phosphorus lyase activity
BC1002_RS17375	COG3626	phosphonate metabolism
BC1002_RS17385	COG3624	Phosphonate C-P lyase system protein PhnG
BC1002_RS17390	COG2188	Transcriptional regulator
BC1002_RS17395	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BC1002_RS17400	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BC1002_RS17405	COG0583	DNA-binding transcription factor activity
BC1002_RS17410	COG1473	amidohydrolase
BC1002_RS17415	COG1414	Transcriptional regulator
BC1002_RS17420	COG2186	Transcriptional regulator
BC1002_RS17425	COG2084	Dehydrogenase
BC1002_RS17430	COG3395	kinase activity
BC1002_RS17435	COG0235	Class ii aldolase
BC1002_RS17440	COG3622	Belongs to the hyi family
BC1002_RS17445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC1002_RS17455	COG1230	cation diffusion facilitator family transporter
BC1002_RS17480	COG2205	protein histidine kinase activity
BC1002_RS17490	COG0583	DNA-binding transcription factor activity
BC1002_RS17495	COG0667	Aldo Keto reductase
BC1002_RS17515	COG0540	Belongs to the ATCase OTCase family
BC1002_RS17520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC1002_RS17555	COG0471	metal ion transport
BC1002_RS17560	COG0039	L-malate dehydrogenase activity
BC1002_RS17605	COG1653	transport
BC1002_RS17610	COG1175	transmembrane transport
BC1002_RS17615	COG0395	ABC-type sugar transport system, permease component
BC1002_RS17620	COG3842	ATPase activity
BC1002_RS17640	COG0840	transmembrane signaling receptor activity
BC1002_RS17655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BC1002_RS17670	COG0471	metal ion transport
BC1002_RS17680	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BC1002_RS17690	COG0471	metal ion transport
BC1002_RS17690	COG3273	potassium ion transport
BC1002_RS17695	COG0405	Gamma-glutamyltransferase
BC1002_RS17705	COG1620	l-lactate permease
BC1002_RS17740	COG1538	Outer membrane efflux protein
BC1002_RS17750	COG5002	protein histidine kinase activity
BC1002_RS17755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BC1002_RS17760	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BC1002_RS17765	COG2353	YceI-like domain
BC1002_RS17770	COG2353	YceI-like domain
BC1002_RS17775	COG3038	cytochrome b561
BC1002_RS17820	COG0784	Response regulator, receiver
BC1002_RS17820	COG4191	Histidine kinase
BC1002_RS17825	COG0457	Tetratricopeptide repeat
BC1002_RS17830	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BC1002_RS17835	COG1215	transferase activity, transferring glycosyl groups
BC1002_RS17840	COG1215	transferase activity, transferring glycosyl groups
BC1002_RS17845	COG0489	protein tyrosine kinase activity
BC1002_RS17860	COG3706	GGDEF domain
BC1002_RS17875	COG3971	2-oxopent-4-enoate hydratase activity
BC1002_RS17885	COG3384	dioxygenase
BC1002_RS17890	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS17900	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC1002_RS17905	COG1846	Transcriptional regulator
BC1002_RS17930	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BC1002_RS17935	COG0673	inositol 2-dehydrogenase activity
BC1002_RS17940	COG0477	Major facilitator Superfamily
BC1002_RS17945	COG0583	DNA-binding transcription factor activity
BC1002_RS17955	COG1335	isochorismatase
BC1002_RS17965	COG0586	Pfam SNARE associated Golgi protein
BC1002_RS17975	COG1902	pentaerythritol trinitrate reductase activity
BC1002_RS17990	COG1414	Transcriptional regulator
BC1002_RS18015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BC1002_RS18040	COG0586	Pfam SNARE associated Golgi protein
BC1002_RS18065	COG1280	lysine exporter protein (LysE YggA)
BC1002_RS18075	COG1742	UPF0060 membrane protein
BC1002_RS18115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BC1002_RS18125	COG0697	spore germination
BC1002_RS18130	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BC1002_RS18135	COG1349	DNA-binding transcription factor activity
BC1002_RS18170	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS18205	COG0583	DNA-binding transcription factor activity
BC1002_RS18220	COG0427	acetyl-CoA hydrolase
BC1002_RS18235	COG1408	metallophosphoesterase
BC1002_RS18255	COG1879	ABC-type sugar transport system periplasmic component
BC1002_RS18260	COG1129	ABC transporter
BC1002_RS18265	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS18270	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS18275	COG2326	polyphosphate kinase activity
BC1002_RS18285	COG2226	methyltransferase
BC1002_RS18330	COG2814	Major facilitator Superfamily
BC1002_RS18340	COG0583	DNA-binding transcription factor activity
BC1002_RS18355	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BC1002_RS18365	COG2188	Transcriptional regulator
BC1002_RS18380	COG0765	amino acid transport
BC1002_RS18385	COG0765	amino acid transport
BC1002_RS18390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS18400	COG0277	FAD linked oxidase domain protein
BC1002_RS18415	COG2205	protein histidine kinase activity
BC1002_RS18415	COG0784	Response regulator, receiver
BC1002_RS18420	COG2197	response regulator
BC1002_RS18430	COG1294	oxidase, subunit
BC1002_RS18435	COG1271	oxidase subunit
BC1002_RS18445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC1002_RS18460	COG2084	Dehydrogenase
BC1002_RS18475	COG2186	Transcriptional regulator
BC1002_RS18480	COG2271	Major facilitator Superfamily
BC1002_RS18490	COG2721	sulfolactate sulfo-lyase activity
BC1002_RS18495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC1002_RS18505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BC1002_RS18520	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BC1002_RS18530	COG0235	Class ii aldolase
BC1002_RS18570	COG0697	spore germination
BC1002_RS18575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC1002_RS18600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BC1002_RS18615	COG0735	belongs to the Fur family
BC1002_RS18640	COG2205	protein histidine kinase activity
BC1002_RS18650	COG3550	peptidyl-serine autophosphorylation
BC1002_RS18675	COG2423	ornithine cyclodeaminase activity
BC1002_RS18680	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BC1002_RS18690	COG0583	DNA-binding transcription factor activity
BC1002_RS18695	COG1064	alcohol dehydrogenase
BC1002_RS18700	COG2207	Transcriptional regulator
BC1002_RS18705	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BC1002_RS18710	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BC1002_RS18735	COG3447	MASE1 domain protein
BC1002_RS18735	COG5001	Diguanylate cyclase
BC1002_RS18735	COG5002	protein histidine kinase activity
BC1002_RS18755	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BC1002_RS18795	COG0628	permease
BC1002_RS18810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BC1002_RS18840	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS18845	COG1764	response to oxidative stress
BC1002_RS18860	COG1846	Transcriptional regulator
BC1002_RS18865	COG1733	regulation of RNA biosynthetic process
BC1002_RS18870	COG0765	amino acid transport
BC1002_RS18875	COG0765	amino acid transport
BC1002_RS18880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS18885	COG3842	ATPase activity
BC1002_RS18905	COG0583	DNA-binding transcription factor activity
BC1002_RS18910	COG0387	Pfam Sodium calcium exchanger
BC1002_RS18920	COG2094	Belongs to the DNA glycosylase MPG family
BC1002_RS18930	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BC1002_RS18935	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC1002_RS18975	COG0753	catalase activity
BC1002_RS18980	COG3038	cytochrome b561
BC1002_RS18985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC1002_RS18990	COG0745	RESPONSE REGULATOR receiver
BC1002_RS19010	COG0778	Nitroreductase
BC1002_RS19045	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
BC1002_RS19090	COG1136	(ABC) transporter
BC1002_RS19120	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BC1002_RS19150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC1002_RS19195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BC1002_RS19210	COG2823	Periplasmic or secreted lipoprotein
BC1002_RS19250	COG1760	l-serine dehydratase
BC1002_RS19265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BC1002_RS19265	COG0446	pyridine nucleotide-disulphide oxidoreductase
BC1002_RS19310	COG1902	pentaerythritol trinitrate reductase activity
BC1002_RS19310	COG0446	pyridine nucleotide-disulphide oxidoreductase
BC1002_RS19315	COG2181	nitrate reductase activity
BC1002_RS19315	COG0247	lactate metabolic process
BC1002_RS19320	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BC1002_RS19340	COG2113	Glycine betaine
BC1002_RS19350	COG0583	DNA-binding transcription factor activity
BC1002_RS19355	COG0625	glutathione transferase activity
BC1002_RS19380	COG0531	amino acid
BC1002_RS19390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC1002_RS19400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC1002_RS19410	COG2271	Major facilitator Superfamily
BC1002_RS19415	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS19420	COG1414	Transcriptional regulator
BC1002_RS19425	COG1077	Cell shape determining protein MreB Mrl
BC1002_RS19435	COG3132	Protein of unknown function, DUF480
BC1002_RS19450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BC1002_RS19455	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BC1002_RS19470	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC1002_RS19490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC1002_RS19495	COG0432	Pfam Uncharacterised protein family UPF0047
BC1002_RS19500	COG3588	fructose-bisphosphate aldolase
BC1002_RS19510	COG0784	Response regulator, receiver
BC1002_RS19510	COG4191	Histidine kinase
BC1002_RS19520	COG0628	permease
BC1002_RS19535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BC1002_RS19540	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BC1002_RS19545	COG2080	2 iron, 2 sulfur cluster binding
BC1002_RS19555	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS19565	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BC1002_RS19565	COG1793	dna ligase
BC1002_RS19570	COG1793	dna ligase
BC1002_RS19570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BC1002_RS19575	COG1295	ribonuclease BN
BC1002_RS19580	COG0028	Belongs to the TPP enzyme family
BC1002_RS19605	COG1881	PFAM PEBP family protein
BC1002_RS19610	COG2207	Transcriptional regulator
BC1002_RS19615	COG0300	oxidoreductase activity
BC1002_RS19630	COG3634	alkyl hydroperoxide reductase activity
BC1002_RS19635	COG0589	response to stress
BC1002_RS19645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BC1002_RS19690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC1002_RS19695	COG0625	glutathione transferase activity
BC1002_RS19775	COG2099	Precorrin-6x reductase
BC1002_RS19780	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BC1002_RS19790	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC1002_RS19815	COG0420	3'-5' exonuclease activity
BC1002_RS19820	COG2733	membrane
BC1002_RS19825	COG0628	permease
BC1002_RS19835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC1002_RS19855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC1002_RS19870	COG0583	DNA-binding transcription factor activity
BC1002_RS19880	COG5002	protein histidine kinase activity
BC1002_RS19890	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BC1002_RS19910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC1002_RS19915	COG1522	sequence-specific DNA binding
BC1002_RS19920	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BC1002_RS19925	COG0583	DNA-binding transcription factor activity
BC1002_RS19930	COG1741	Belongs to the pirin family
BC1002_RS19935	COG2259	Doxx family
BC1002_RS19950	COG3634	alkyl hydroperoxide reductase activity
BC1002_RS19960	COG3829	transcription factor binding
BC1002_RS19970	COG0477	Major facilitator Superfamily
BC1002_RS19995	COG0583	DNA-binding transcription factor activity
BC1002_RS20030	COG0668	transmembrane transport
BC1002_RS20035	COG1199	ATP-dependent helicase activity
BC1002_RS20035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BC1002_RS20050	COG1139	Iron-sulfur cluster binding protein
BC1002_RS20055	COG0247	lactate metabolic process
BC1002_RS20075	COG2186	Transcriptional regulator
BC1002_RS20100	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BC1002_RS20130	COG0693	protein deglycase activity
BC1002_RS20175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC1002_RS20180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC1002_RS20190	COG2207	Transcriptional regulator
BC1002_RS20195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC1002_RS20210	COG0667	Aldo Keto reductase
BC1002_RS20215	COG1201	RNA secondary structure unwinding
BC1002_RS20220	COG5001	Diguanylate cyclase
BC1002_RS20225	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BC1002_RS20245	COG0477	Major facilitator Superfamily
BC1002_RS20255	COG1764	response to oxidative stress
BC1002_RS20270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC1002_RS20285	COG3246	L-lysine catabolic process to acetate
BC1002_RS20290	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS20300	COG1024	Enoyl-CoA hydratase
BC1002_RS20310	COG2271	Major facilitator Superfamily
BC1002_RS20320	COG0477	Major facilitator Superfamily
BC1002_RS20325	COG0183	Belongs to the thiolase family
BC1002_RS20330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC1002_RS20350	COG2070	2-Nitropropane dioxygenase
BC1002_RS20355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC1002_RS20360	COG1024	Enoyl-CoA hydratase
BC1002_RS20365	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS20370	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS20375	COG0183	Belongs to the thiolase family
BC1002_RS20380	COG1024	Enoyl-CoA hydratase
BC1002_RS20380	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC1002_RS20385	COG0583	DNA-binding transcription factor activity
BC1002_RS20405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC1002_RS20415	COG0596	Alpha beta hydrolase
BC1002_RS20420	COG0596	Alpha beta hydrolase
BC1002_RS20460	COG0372	Belongs to the citrate synthase family
BC1002_RS20470	COG0596	Alpha beta hydrolase
BC1002_RS20480	COG1077	Cell shape determining protein MreB Mrl
BC1002_RS20490	COG2814	Major facilitator Superfamily
BC1002_RS20505	COG2267	carboxylic ester hydrolase activity
BC1002_RS20515	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS20540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC1002_RS20545	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BC1002_RS20550	COG3971	2-oxopent-4-enoate hydratase activity
BC1002_RS20555	COG3384	dioxygenase
BC1002_RS20585	COG0543	2 iron, 2 sulfur cluster binding
BC1002_RS20585	COG0633	Ferredoxin
BC1002_RS20610	COG0318	PFAM AMP-dependent synthetase and ligase
BC1002_RS20620	COG0523	cobalamin synthesis protein
BC1002_RS20665	COG4974	Belongs to the 'phage' integrase family
BC1002_RS20680	COG2814	Major facilitator Superfamily
BC1002_RS20690	COG0840	transmembrane signaling receptor activity
BC1002_RS20695	COG1902	pentaerythritol trinitrate reductase activity
BC1002_RS20695	COG0446	pyridine nucleotide-disulphide oxidoreductase
BC1002_RS20700	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS20720	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS20740	COG2353	YceI-like domain
BC1002_RS20745	COG2186	Transcriptional regulator
BC1002_RS20750	COG3246	L-lysine catabolic process to acetate
BC1002_RS20755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC1002_RS20805	COG1309	transcriptional regulator
BC1002_RS20820	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BC1002_RS20825	COG1309	transcriptional regulator
BC1002_RS20830	COG4447	cellulose binding
BC1002_RS20860	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BC1002_RS20930	COG1695	Transcriptional regulator
BC1002_RS20935	COG2375	cellular response to nickel ion
BC1002_RS20940	COG2814	Major facilitator Superfamily
BC1002_RS20945	COG0628	permease
BC1002_RS20950	COG3237	CsbD-like
BC1002_RS20965	COG1024	Enoyl-CoA hydratase
BC1002_RS20970	COG1024	Enoyl-CoA hydratase
BC1002_RS20990	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS21005	COG0330	HflC and HflK could
BC1002_RS21015	COG1671	Belongs to the UPF0178 family
BC1002_RS21020	COG2252	PERMEase
BC1002_RS21025	COG3038	cytochrome b561
BC1002_RS21065	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BC1002_RS21080	COG3707	response regulator
BC1002_RS21085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC1002_RS21090	COG1879	ABC-type sugar transport system periplasmic component
BC1002_RS21100	COG4211	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS21105	COG1129	ABC transporter
BC1002_RS21110	COG3618	amidohydrolase
BC1002_RS21115	COG3254	rhamnose metabolic process
BC1002_RS21120	COG0583	DNA-binding transcription factor activity
BC1002_RS21130	COG4948	Mandelate Racemase Muconate Lactonizing
BC1002_RS21135	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS21170	COG0484	heat shock protein binding
BC1002_RS21175	COG0655	NAD(P)H dehydrogenase (quinone) activity
BC1002_RS21195	COG2134	cdp-diacylglycerol pyrophosphatase
BC1002_RS21250	COG3300	MHYT domain
BC1002_RS21250	COG5001	Diguanylate cyclase
BC1002_RS21260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BC1002_RS21265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC1002_RS21280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC1002_RS21295	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS21355	COG3179	chitinase
BC1002_RS21360	COG3501	Rhs element vgr protein
BC1002_RS21430	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BC1002_RS21435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC1002_RS21440	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS21455	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BC1002_RS21470	COG3300	MHYT domain
BC1002_RS21470	COG5001	Diguanylate cyclase
BC1002_RS21480	COG0583	DNA-binding transcription factor activity
BC1002_RS21485	COG2271	Major facilitator Superfamily
BC1002_RS21510	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BC1002_RS21515	COG0174	glutamine synthetase
BC1002_RS21525	COG0596	Alpha beta hydrolase
BC1002_RS21535	COG2814	Major facilitator Superfamily
BC1002_RS21560	COG0417	DNA replication proofreading
BC1002_RS21580	COG1864	DNA RNA non-specific endonuclease
BC1002_RS21580	COG3591	Belongs to the peptidase S1B family
BC1002_RS21585	COG2271	Major facilitator Superfamily
BC1002_RS21590	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BC1002_RS21595	COG0583	DNA-binding transcription factor activity
BC1002_RS21615	COG3123	guanosine phosphorylase activity
BC1002_RS21655	COG3384	dioxygenase
BC1002_RS21670	COG0583	DNA-binding transcription factor activity
BC1002_RS21700	COG0738	Major facilitator superfamily
BC1002_RS21710	COG0739	heme binding
BC1002_RS21735	COG0395	ABC-type sugar transport system, permease component
BC1002_RS21755	COG3842	ATPase activity
BC1002_RS21760	COG1609	Transcriptional regulator
BC1002_RS21785	COG1940	carbohydrate kinase activity
BC1002_RS21805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC1002_RS21815	COG2271	Major facilitator Superfamily
BC1002_RS21820	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BC1002_RS21825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BC1002_RS21830	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BC1002_RS21830	COG1082	Xylose isomerase domain protein TIM barrel
BC1002_RS21870	COG3938	Belongs to the proline racemase family
BC1002_RS21875	COG0745	RESPONSE REGULATOR receiver
BC1002_RS21880	COG0477	Major facilitator Superfamily
BC1002_RS21895	COG2259	Doxx family
BC1002_RS21905	COG4154	Belongs to the RbsD FucU family
BC1002_RS21920	COG3657	addiction module killer protein
BC1002_RS21950	COG1914	H( )-stimulated, divalent metal cation uptake system
BC1002_RS21970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BC1002_RS21980	COG0583	DNA-binding transcription factor activity
BC1002_RS22000	COG0667	Aldo Keto reductase
BC1002_RS22010	COG2902	Dehydrogenase
BC1002_RS22015	COG0596	Alpha beta hydrolase
BC1002_RS22015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BC1002_RS22015	COG2226	methyltransferase
BC1002_RS22050	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BC1002_RS22055	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BC1002_RS22060	COG3639	organic phosphonate transmembrane transporter activity
BC1002_RS22080	COG0657	acetylesterase activity
BC1002_RS22095	COG0546	phosphoglycolate phosphatase activity
BC1002_RS22100	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BC1002_RS22105	COG0583	DNA-binding transcription factor activity
BC1002_RS22110	COG1253	flavin adenine dinucleotide binding
BC1002_RS22140	COG4774	siderophore transport
BC1002_RS22150	COG3128	pkhd-type hydroxylase
BC1002_RS22185	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BC1002_RS22200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC1002_RS22210	COG2916	Histone family protein nucleoid-structuring protein H-NS
BC1002_RS22235	COG0545	Peptidyl-prolyl cis-trans isomerase
BC1002_RS22275	COG0840	transmembrane signaling receptor activity
BC1002_RS22285	COG1295	ribonuclease BN
BC1002_RS22290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BC1002_RS22310	COG2308	Evidence 4 Homologs of previously reported genes of
BC1002_RS22325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC1002_RS22335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC1002_RS22395	COG0671	phosphoesterase, PA-phosphatase related
BC1002_RS22405	COG0583	DNA-binding transcription factor activity
BC1002_RS22415	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BC1002_RS22420	COG1305	Transglutaminase-like
BC1002_RS22550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS22570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC1002_RS22590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC1002_RS22595	COG0601	transmembrane transport
BC1002_RS22605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC1002_RS22615	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS22625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BC1002_RS22635	COG1522	sequence-specific DNA binding
BC1002_RS22640	COG0473	3-isopropylmalate dehydrogenase activity
BC1002_RS22645	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS22655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BC1002_RS22675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC1002_RS22740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC1002_RS22745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BC1002_RS22755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BC1002_RS22770	COG0302	gtp cyclohydrolase
BC1002_RS22780	COG2203	Gaf domain
BC1002_RS22780	COG4251	negative regulation of phosphorylation
BC1002_RS22780	COG5001	Diguanylate cyclase
BC1002_RS22780	COG3706	GGDEF domain
BC1002_RS22795	COG0306	phosphate transporter
BC1002_RS22810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC1002_RS22860	COG1045	serine acetyltransferase
BC1002_RS22895	COG3842	ATPase activity
BC1002_RS22935	COG0589	response to stress
BC1002_RS22940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC1002_RS22945	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BC1002_RS22955	COG1335	isochorismatase
BC1002_RS22960	COG4566	intracellular signal transduction
BC1002_RS23000	COG0583	DNA-binding transcription factor activity
BC1002_RS23015	COG4191	Histidine kinase
BC1002_RS23020	COG0753	catalase activity
BC1002_RS23035	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC1002_RS23045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BC1002_RS23080	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS23085	COG4566	intracellular signal transduction
BC1002_RS23090	COG0784	Response regulator, receiver
BC1002_RS23120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC1002_RS23130	COG3706	GGDEF domain
BC1002_RS23145	COG3706	GGDEF domain
BC1002_RS23150	COG0129	dihydroxy-acid dehydratase activity
BC1002_RS23155	COG0683	leucine binding
BC1002_RS23160	COG2816	NAD+ diphosphatase activity
BC1002_RS23165	COG1280	lysine exporter protein (LysE YggA)
BC1002_RS23170	COG1879	ABC-type sugar transport system periplasmic component
BC1002_RS23180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC1002_RS23235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BC1002_RS23255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BC1002_RS23305	COG1063	alcohol dehydrogenase
BC1002_RS23310	COG3618	amidohydrolase
BC1002_RS23325	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS23340	COG2159	amidohydrolase
BC1002_RS23345	COG3384	dioxygenase
BC1002_RS23355	COG0473	3-isopropylmalate dehydrogenase activity
BC1002_RS23355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BC1002_RS23360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BC1002_RS23365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BC1002_RS23370	COG1802	Transcriptional regulator
BC1002_RS23375	COG0412	Dienelactone hydrolase
BC1002_RS23385	COG0477	Major facilitator Superfamily
BC1002_RS23390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BC1002_RS23425	COG2271	Major facilitator Superfamily
BC1002_RS23435	COG1073	alpha beta
BC1002_RS23440	COG2814	Major facilitator Superfamily
BC1002_RS23445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC1002_RS23450	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BC1002_RS23455	COG3971	2-oxopent-4-enoate hydratase activity
BC1002_RS23460	COG3384	dioxygenase
BC1002_RS23465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC1002_RS23470	COG1414	Transcriptional regulator
BC1002_RS23475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC1002_RS23480	COG0642	Histidine kinase
BC1002_RS23485	COG0745	RESPONSE REGULATOR receiver
BC1002_RS23490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC1002_RS23500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC1002_RS23535	COG1562	ergosterol biosynthetic process
BC1002_RS23540	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BC1002_RS23550	COG1275	C4-dicarboxylate transporter malic acid transport protein
BC1002_RS23585	COG2204	response regulator
BC1002_RS23595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BC1002_RS23600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BC1002_RS23610	COG1538	Outer membrane efflux protein
BC1002_RS23630	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BC1002_RS23630	COG0515	serine threonine protein kinase
BC1002_RS23635	COG0515	serine threonine protein kinase
BC1002_RS23635	COG2815	serine threonine protein kinase
BC1002_RS23655	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS23665	COG1522	sequence-specific DNA binding
BC1002_RS23685	COG2267	carboxylic ester hydrolase activity
BC1002_RS23710	COG1472	Belongs to the glycosyl hydrolase 3 family
BC1002_RS23740	COG2860	membrane
BC1002_RS23770	COG4964	Belongs to the GSP D family
BC1002_RS23805	COG0463	Glycosyl transferase, family 2
BC1002_RS23825	COG1737	Transcriptional regulator
BC1002_RS23835	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS23850	COG0395	ABC-type sugar transport system, permease component
BC1002_RS23865	COG0583	DNA-binding transcription factor activity
BC1002_RS23890	COG3300	MHYT domain
BC1002_RS23890	COG5001	Diguanylate cyclase
BC1002_RS23900	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS23905	COG1129	ABC transporter
BC1002_RS23915	COG4948	Mandelate Racemase Muconate Lactonizing
BC1002_RS23920	COG0583	DNA-binding transcription factor activity
BC1002_RS23930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BC1002_RS23935	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BC1002_RS23965	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BC1002_RS23985	COG0477	Major facilitator Superfamily
BC1002_RS24000	COG0765	amino acid transport
BC1002_RS24005	COG0765	amino acid transport
BC1002_RS24015	COG1126	abc transporter atp-binding protein
BC1002_RS24020	COG0006	proline dipeptidase activity
BC1002_RS24025	COG3321	synthase
BC1002_RS24025	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS24025	COG0604	alcohol dehydrogenase
BC1002_RS24050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC1002_RS24055	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS24060	COG1522	sequence-specific DNA binding
BC1002_RS24065	COG3608	succinylglutamate desuccinylase aspartoacylase
BC1002_RS24070	COG2423	ornithine cyclodeaminase activity
BC1002_RS24075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BC1002_RS24080	COG1725	Transcriptional regulator
BC1002_RS24105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC1002_RS24125	COG2204	response regulator
BC1002_RS24170	COG0667	Aldo Keto reductase
BC1002_RS24185	COG0626	cystathionine gamma-synthase activity
BC1002_RS24210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BC1002_RS24210	COG2755	lipolytic protein G-D-S-L family
BC1002_RS24240	COG0753	catalase activity
BC1002_RS24255	COG3468	outer membrane autotransporter barrel domain protein
BC1002_RS24265	COG0583	DNA-binding transcription factor activity
BC1002_RS24295	COG0657	acetylesterase activity
BC1002_RS24325	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BC1002_RS24360	COG0025	NhaP-type Na H and K H
BC1002_RS24365	COG1741	Belongs to the pirin family
BC1002_RS24370	COG0492	ferredoxin-NADP+ reductase activity
BC1002_RS24375	COG0583	DNA-binding transcription factor activity
BC1002_RS24395	COG0583	DNA-binding transcription factor activity
BC1002_RS24400	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS24455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC1002_RS24475	COG0450	alkyl hydroperoxide reductase
BC1002_RS24485	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BC1002_RS24500	COG1335	isochorismatase
BC1002_RS24520	COG4566	intracellular signal transduction
BC1002_RS24525	COG4566	intracellular signal transduction
BC1002_RS24530	COG4191	Histidine kinase
BC1002_RS24535	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BC1002_RS24580	COG1335	isochorismatase
BC1002_RS24595	COG2814	Major facilitator Superfamily
BC1002_RS24600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BC1002_RS24605	COG4191	Histidine kinase
BC1002_RS24615	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BC1002_RS24620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BC1002_RS24635	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS24645	COG1024	Enoyl-CoA hydratase
BC1002_RS24650	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS24720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BC1002_RS24760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BC1002_RS24765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC1002_RS24785	COG4941	Belongs to the sigma-70 factor family
BC1002_RS24790	COG3795	YCII-related domain
BC1002_RS24795	COG3795	YCII-related domain
BC1002_RS24835	COG3128	pkhd-type hydroxylase
BC1002_RS24840	COG4774	siderophore transport
BC1002_RS24845	COG0667	Aldo Keto reductase
BC1002_RS24850	COG1881	PFAM PEBP family protein
BC1002_RS24865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BC1002_RS24880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC1002_RS24890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS24905	COG0583	DNA-binding transcription factor activity
BC1002_RS24910	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS24930	COG0463	Glycosyl transferase, family 2
BC1002_RS24935	COG3038	cytochrome b561
BC1002_RS24945	COG1309	transcriptional regulator
BC1002_RS24950	COG0625	glutathione transferase activity
BC1002_RS24955	COG2814	Major facilitator Superfamily
BC1002_RS24960	COG0477	Major facilitator Superfamily
BC1002_RS24990	COG2271	Major facilitator Superfamily
BC1002_RS25020	COG0583	DNA-binding transcription factor activity
BC1002_RS25120	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BC1002_RS25125	COG1254	Belongs to the acylphosphatase family
BC1002_RS25130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC1002_RS25140	COG1215	transferase activity, transferring glycosyl groups
BC1002_RS25155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BC1002_RS25170	COG2853	Lipoprotein
BC1002_RS25200	COG1657	PFAM Prenyltransferase squalene oxidase
BC1002_RS25205	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BC1002_RS25210	COG1562	ergosterol biosynthetic process
BC1002_RS25225	COG3437	response regulator, receiver
BC1002_RS25250	COG1595	DNA-templated transcription, initiation
BC1002_RS25260	COG3813	Protein conserved in bacteria
BC1002_RS25265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC1002_RS25270	COG1393	Belongs to the ArsC family
BC1002_RS25280	COG1192	Involved in chromosome partitioning
BC1002_RS25320	COG1063	alcohol dehydrogenase
BC1002_RS25325	COG2353	YceI-like domain
BC1002_RS25365	COG4638	Rieske (2fe-2S)
BC1002_RS25380	COG4191	Histidine kinase
BC1002_RS25400	COG0154	amidase activity
BC1002_RS25410	COG4566	intracellular signal transduction
BC1002_RS25430	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS25445	COG0583	DNA-binding transcription factor activity
BC1002_RS25450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC1002_RS25455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC1002_RS25460	COG2271	Major facilitator Superfamily
BC1002_RS25465	COG1802	Transcriptional regulator
BC1002_RS25470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BC1002_RS25475	COG2271	Major facilitator Superfamily
BC1002_RS25485	COG0247	lactate metabolic process
BC1002_RS25490	COG1609	Transcriptional regulator
BC1002_RS25490	COG2207	Transcriptional regulator
BC1002_RS25515	COG0492	ferredoxin-NADP+ reductase activity
BC1002_RS25530	COG2610	gluconate transmembrane transporter activity
BC1002_RS25535	COG2204	response regulator
BC1002_RS25565	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BC1002_RS25570	COG0045	succinate-CoA ligase (ADP-forming) activity
BC1002_RS25570	COG1042	CoA-binding domain protein
BC1002_RS25570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC1002_RS25595	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS25610	COG0840	transmembrane signaling receptor activity
BC1002_RS25615	COG1278	Cold shock
BC1002_RS25620	COG2942	2-epimerase
BC1002_RS25635	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC1002_RS25655	COG0840	transmembrane signaling receptor activity
BC1002_RS25665	COG2808	Putative FMN-binding domain
BC1002_RS25685	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BC1002_RS25710	COG0039	L-malate dehydrogenase activity
BC1002_RS25715	COG2188	Transcriptional regulator
BC1002_RS25730	COG1053	succinate dehydrogenase
BC1002_RS25735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BC1002_RS25740	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BC1002_RS25745	COG0372	Belongs to the citrate synthase family
BC1002_RS25750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BC1002_RS25755	COG5510	response to toxic substance
BC1002_RS25760	COG0066	3-isopropylmalate dehydratase activity
BC1002_RS25765	COG0473	3-isopropylmalate dehydrogenase activity
BC1002_RS25780	COG0101	tRNA pseudouridine synthase activity
BC1002_RS25785	COG0135	phosphoribosylanthranilate isomerase activity
BC1002_RS25790	COG0133	tryptophan synthase activity
BC1002_RS25800	COG0159	tryptophan synthase activity
BC1002_RS25805	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BC1002_RS25810	COG0285	dihydrofolate synthase activity
BC1002_RS25845	COG1253	flavin adenine dinucleotide binding
BC1002_RS25855	COG1640	4-alpha-glucanotransferase
BC1002_RS25860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BC1002_RS25870	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BC1002_RS25875	COG0366	Alpha amylase catalytic
BC1002_RS25880	COG0366	Alpha amylase catalytic
BC1002_RS25900	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BC1002_RS25900	COG2010	Cytochrome c
BC1002_RS25910	COG5654	RES domain protein
BC1002_RS25915	COG5642	Protein of unknown function (DUF2384)
BC1002_RS25925	COG0583	DNA-binding transcription factor activity
BC1002_RS25930	COG1942	4-Oxalocrotonate Tautomerase
BC1002_RS25940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BC1002_RS25945	COG0798	PFAM Bile acid sodium symporter
BC1002_RS25950	COG0492	ferredoxin-NADP+ reductase activity
BC1002_RS25970	COG3842	ATPase activity
BC1002_RS25975	COG4149	molybdate abc transporter
BC1002_RS25980	COG0725	ABC transporter, periplasmic molybdate-binding protein
BC1002_RS26000	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BC1002_RS26005	COG0415	Belongs to the DNA photolyase family
BC1002_RS26010	COG1764	response to oxidative stress
BC1002_RS26015	COG1846	Transcriptional regulator
BC1002_RS26025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BC1002_RS26035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BC1002_RS26040	COG1611	Belongs to the LOG family
BC1002_RS26050	COG1252	NADH dehydrogenase
BC1002_RS26055	COG0412	Dienelactone hydrolase
BC1002_RS26070	COG1722	exodeoxyribonuclease VII activity
BC1002_RS26075	COG0142	geranyltranstransferase activity
BC1002_RS26080	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BC1002_RS26085	COG1469	GTP cyclohydrolase I activity
BC1002_RS26090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BC1002_RS26095	COG2081	HI0933 family
BC1002_RS26100	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BC1002_RS26115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BC1002_RS26125	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BC1002_RS26145	COG0318	PFAM AMP-dependent synthetase and ligase
BC1002_RS26160	COG3485	protocatechuate 3,4-dioxygenase
BC1002_RS26165	COG3485	protocatechuate 3,4-dioxygenase
BC1002_RS26170	COG0583	DNA-binding transcription factor activity
BC1002_RS26190	COG0247	lactate metabolic process
BC1002_RS26190	COG0277	FAD linked oxidase domain protein
BC1002_RS26200	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BC1002_RS26220	COG2207	Transcriptional regulator
BC1002_RS26220	COG1609	Transcriptional regulator
BC1002_RS26225	COG2115	Belongs to the xylose isomerase family
BC1002_RS26230	COG4213	ABC transporter substrate-binding protein
BC1002_RS26235	COG1129	ABC transporter
BC1002_RS26240	COG4214	carbohydrate transport
BC1002_RS26270	COG1289	transmembrane transporter activity
BC1002_RS26285	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BC1002_RS26350	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BC1002_RS26355	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS26370	COG2301	Belongs to the HpcH HpaI aldolase family
BC1002_RS26375	COG3507	Belongs to the glycosyl hydrolase 43 family
BC1002_RS26380	COG2271	Major facilitator Superfamily
BC1002_RS26385	COG0583	DNA-binding transcription factor activity
BC1002_RS26395	COG2814	Major facilitator Superfamily
BC1002_RS26400	COG0583	DNA-binding transcription factor activity
BC1002_RS26405	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS26410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC1002_RS26415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC1002_RS26420	COG4269	membrane
BC1002_RS26475	COG2376	Dihydroxyacetone kinase
BC1002_RS26485	COG0701	Predicted permease
BC1002_RS26490	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BC1002_RS26495	COG0709	Synthesizes selenophosphate from selenide and ATP
BC1002_RS26505	COG0243	molybdopterin cofactor binding
BC1002_RS26505	COG3383	formate dehydrogenase (NAD+) activity
BC1002_RS26510	COG3383	formate dehydrogenase (NAD+) activity
BC1002_RS26510	COG0243	molybdopterin cofactor binding
BC1002_RS26515	COG0437	4 iron, 4 sulfur cluster binding
BC1002_RS26520	COG2864	formate dehydrogenase
BC1002_RS26525	COG3058	Necessary for formate dehydrogenase activity
BC1002_RS26535	COG3276	selenocysteine insertion sequence binding
BC1002_RS26560	COG2271	Major facilitator Superfamily
BC1002_RS26575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC1002_RS26580	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BC1002_RS26595	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS26600	COG0583	DNA-binding transcription factor activity
BC1002_RS26615	COG2207	Transcriptional regulator
BC1002_RS26630	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BC1002_RS26680	COG1294	oxidase, subunit
BC1002_RS26685	COG1271	oxidase subunit
BC1002_RS26690	COG0243	molybdopterin cofactor binding
BC1002_RS26700	COG4191	Histidine kinase
BC1002_RS26705	COG4566	intracellular signal transduction
BC1002_RS26720	COG4191	Histidine kinase
BC1002_RS26725	COG0667	Aldo Keto reductase
BC1002_RS26730	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BC1002_RS26745	COG4566	intracellular signal transduction
BC1002_RS26750	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS26785	COG0657	acetylesterase activity
BC1002_RS26790	COG4566	intracellular signal transduction
BC1002_RS26795	COG4191	Histidine kinase
BC1002_RS26800	COG2837	iron assimilation
BC1002_RS26830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BC1002_RS26880	COG1396	sequence-specific DNA binding
BC1002_RS26885	COG4771	TonB-dependent receptor
BC1002_RS26915	COG4166	transmembrane transport
BC1002_RS26920	COG4174	ABC transporter (Permease)
BC1002_RS26925	COG4239	(ABC) transporter, permease
BC1002_RS26930	COG4172	Belongs to the ABC transporter superfamily
BC1002_RS26955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC1002_RS27030	COG1301	dicarboxylic acid transport
BC1002_RS27035	COG1794	racemase activity, acting on amino acids and derivatives
BC1002_RS27080	COG0671	phosphoesterase, PA-phosphatase related
BC1002_RS27095	COG0501	Belongs to the peptidase M48B family
BC1002_RS27100	COG1704	LemA family
BC1002_RS27130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC1002_RS27155	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS27180	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS27240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC1002_RS27245	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BC1002_RS27255	COG0583	DNA-binding transcription factor activity
BC1002_RS27270	COG1304	FMN binding
BC1002_RS27280	COG1129	ABC transporter
BC1002_RS27305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BC1002_RS27305	COG2010	Cytochrome c
BC1002_RS27310	COG2080	2 iron, 2 sulfur cluster binding
BC1002_RS27315	COG2010	Cytochrome c
BC1002_RS27315	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BC1002_RS27330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BC1002_RS27330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC1002_RS27345	COG0693	protein deglycase activity
BC1002_RS27355	COG2814	Major facilitator Superfamily
BC1002_RS27370	COG1024	Enoyl-CoA hydratase
BC1002_RS27375	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS27385	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS27410	COG4191	Histidine kinase
BC1002_RS27420	COG4566	intracellular signal transduction
BC1002_RS27430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BC1002_RS27440	COG1538	Outer membrane efflux protein
BC1002_RS27445	COG2995	paraquat-inducible protein a
BC1002_RS27450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BC1002_RS27450	COG3008	intermembrane lipid transfer
BC1002_RS27470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BC1002_RS27475	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BC1002_RS27500	COG3064	Membrane
BC1002_RS27540	COG0546	phosphoglycolate phosphatase activity
BC1002_RS27545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC1002_RS27595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC1002_RS27605	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BC1002_RS27605	COG1672	PFAM Archaeal ATPase
BC1002_RS27645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BC1002_RS27650	COG1879	ABC-type sugar transport system periplasmic component
BC1002_RS27655	COG3386	PFAM SMP-30 Gluconolaconase
BC1002_RS27660	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS27670	COG1129	ABC transporter
BC1002_RS27675	COG1879	ABC-type sugar transport system periplasmic component
BC1002_RS27685	COG1070	Carbohydrate kinase
BC1002_RS27690	COG4977	sequence-specific DNA binding
BC1002_RS27690	COG1917	Cupin 2, conserved barrel domain protein
BC1002_RS27695	COG3842	ATPase activity
BC1002_RS27700	COG1063	alcohol dehydrogenase
BC1002_RS27705	COG3833	ABC-type maltose transport systems, permease component
BC1002_RS27740	COG2186	Transcriptional regulator
BC1002_RS27745	COG2271	Major facilitator Superfamily
BC1002_RS27750	COG0277	FAD linked oxidase domain protein
BC1002_RS27795	COG4993	Dehydrogenase
BC1002_RS27805	COG1271	oxidase subunit
BC1002_RS27810	COG1294	oxidase, subunit
BC1002_RS27835	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS27840	COG0583	DNA-binding transcription factor activity
BC1002_RS27865	COG0625	glutathione transferase activity
BC1002_RS27880	COG1309	transcriptional regulator
BC1002_RS27885	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS27920	COG2144	transferase activity, transferring acyl groups
BC1002_RS27925	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS27935	COG2072	flavoprotein involved in K transport
BC1002_RS27945	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC1002_RS27945	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC1002_RS27980	COG0183	Belongs to the thiolase family
BC1002_RS27985	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BC1002_RS27990	COG0583	DNA-binding transcription factor activity
BC1002_RS28000	COG1414	Transcriptional regulator
BC1002_RS28015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC1002_RS28020	COG0444	Belongs to the ABC transporter superfamily
BC1002_RS28025	COG4608	Belongs to the ABC transporter superfamily
BC1002_RS28045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC1002_RS28050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC1002_RS28055	COG1116	anion transmembrane transporter activity
BC1002_RS28100	COG3842	ATPase activity
BC1002_RS28130	COG0459	protein refolding
BC1002_RS28140	COG0071	Belongs to the small heat shock protein (HSP20) family
BC1002_RS28175	COG0444	Belongs to the ABC transporter superfamily
BC1002_RS28180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC1002_RS28185	COG0601	transmembrane transport
BC1002_RS28190	COG0747	negative chemotaxis
BC1002_RS28195	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BC1002_RS28215	COG1177	transmembrane transport
BC1002_RS28220	COG1176	ABC-type spermidine putrescine transport system, permease component I
BC1002_RS28240	COG1802	Transcriptional regulator
BC1002_RS28245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BC1002_RS28270	COG1129	ABC transporter
BC1002_RS28275	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS28315	COG2207	Transcriptional regulator
BC1002_RS28355	COG2826	transposase and inactivated derivatives, IS30 family
BC1002_RS28380	COG0583	DNA-binding transcription factor activity
BC1002_RS28390	COG0477	Major facilitator Superfamily
BC1002_RS28400	COG1024	Enoyl-CoA hydratase
BC1002_RS28400	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC1002_RS28430	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BC1002_RS28435	COG0583	DNA-binding transcription factor activity
BC1002_RS28440	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS28445	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BC1002_RS28460	COG0477	Major facilitator Superfamily
BC1002_RS28480	COG2030	dehydratase
BC1002_RS28485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC1002_RS28490	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS28495	COG2030	dehydratase
BC1002_RS28500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BC1002_RS28510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BC1002_RS28510	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BC1002_RS28515	COG1024	Enoyl-CoA hydratase
BC1002_RS28520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC1002_RS28525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BC1002_RS28545	COG0741	lytic transglycosylase activity
BC1002_RS28550	COG1744	ABC transporter substrate-binding protein PnrA-like
BC1002_RS28560	COG0745	RESPONSE REGULATOR receiver
BC1002_RS28595	COG1176	ABC-type spermidine putrescine transport system, permease component I
BC1002_RS28620	COG2271	Major facilitator Superfamily
BC1002_RS28665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BC1002_RS28690	COG2267	carboxylic ester hydrolase activity
BC1002_RS28695	COG3384	dioxygenase
BC1002_RS28700	COG2814	Major facilitator Superfamily
BC1002_RS28705	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS28715	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC1002_RS28730	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC1002_RS28735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC1002_RS28765	COG2271	Major facilitator Superfamily
BC1002_RS28770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC1002_RS28805	COG1414	Transcriptional regulator
BC1002_RS28815	COG1802	Transcriptional regulator
BC1002_RS28875	COG2011	ABC-type metal ion transport system permease component
BC1002_RS28880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BC1002_RS28885	COG1464	Belongs to the NlpA lipoprotein family
BC1002_RS28890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC1002_RS28910	COG0583	DNA-binding transcription factor activity
BC1002_RS28920	COG1960	acyl-CoA dehydrogenase activity
BC1002_RS28925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC1002_RS28965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC1002_RS28980	COG0667	Aldo Keto reductase
BC1002_RS28985	COG0747	negative chemotaxis
BC1002_RS28995	COG4172	Belongs to the ABC transporter superfamily
BC1002_RS29000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC1002_RS29010	COG0747	negative chemotaxis
BC1002_RS29030	COG0559	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS29040	COG0583	DNA-binding transcription factor activity
BC1002_RS29045	COG2072	flavoprotein involved in K transport
BC1002_RS29070	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BC1002_RS29080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC1002_RS29105	COG0583	DNA-binding transcription factor activity
BC1002_RS29125	COG4974	Belongs to the 'phage' integrase family
BC1002_RS29135	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS29155	COG0596	Alpha beta hydrolase
BC1002_RS29170	COG0281	malic enzyme
BC1002_RS29170	COG0280	phosphate acetyltransferase
BC1002_RS29175	COG0583	DNA-binding transcription factor activity
BC1002_RS29195	COG1301	dicarboxylic acid transport
BC1002_RS29205	COG1309	transcriptional regulator
BC1002_RS29210	COG0697	spore germination
BC1002_RS29220	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS29275	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BC1002_RS29300	COG1846	Transcriptional regulator
BC1002_RS29300	COG0456	acetyltransferase
BC1002_RS29330	COG0129	dihydroxy-acid dehydratase activity
BC1002_RS29365	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC1002_RS29385	COG0477	Major facilitator Superfamily
BC1002_RS29390	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BC1002_RS29400	COG1053	succinate dehydrogenase
BC1002_RS29405	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS29440	COG0559	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS29470	COG0656	L-ascorbic acid biosynthetic process
BC1002_RS29475	COG0477	Major facilitator Superfamily
BC1002_RS29490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC1002_RS29500	COG2197	response regulator
BC1002_RS29545	COG0625	glutathione transferase activity
BC1002_RS29595	COG2197	response regulator
BC1002_RS29610	COG0784	Response regulator, receiver
BC1002_RS29610	COG4191	Histidine kinase
BC1002_RS29615	COG0494	nUDIX hydrolase
BC1002_RS29625	COG2186	Transcriptional regulator
BC1002_RS29635	COG1129	ABC transporter
BC1002_RS29640	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS29645	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS29680	COG2072	flavoprotein involved in K transport
BC1002_RS29685	COG0583	DNA-binding transcription factor activity
BC1002_RS29695	COG3842	ATPase activity
BC1002_RS29710	COG1177	transmembrane transport
BC1002_RS29720	COG2329	Antibiotic biosynthesis monooxygenase
BC1002_RS29745	COG0513	Belongs to the DEAD box helicase family
BC1002_RS29760	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS29795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC1002_RS29855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC1002_RS29865	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC1002_RS29870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BC1002_RS29885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BC1002_RS29885	COG0617	tRNA 3'-terminal CCA addition
BC1002_RS29885	COG0517	IMP dehydrogenase activity
BC1002_RS29900	COG2391	methyltransferase activity
BC1002_RS29940	COG0840	transmembrane signaling receptor activity
BC1002_RS29950	COG1129	ABC transporter
BC1002_RS29960	COG0559	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS29970	COG1653	transport
BC1002_RS29975	COG1175	transmembrane transport
BC1002_RS29980	COG0395	ABC-type sugar transport system, permease component
BC1002_RS29990	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS30010	COG0683	leucine binding
BC1002_RS30040	COG0583	DNA-binding transcription factor activity
BC1002_RS30050	COG1309	transcriptional regulator
BC1002_RS30070	COG4941	Belongs to the sigma-70 factor family
BC1002_RS30100	COG1309	transcriptional regulator
BC1002_RS30145	COG0583	DNA-binding transcription factor activity
BC1002_RS30155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BC1002_RS30210	COG3618	amidohydrolase
BC1002_RS30215	COG0583	DNA-binding transcription factor activity
BC1002_RS30220	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS30225	COG2271	Major facilitator Superfamily
BC1002_RS30230	COG3959	Transketolase, thiamine diphosphate binding domain
BC1002_RS30235	COG3958	Transketolase
BC1002_RS30265	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS30280	COG0589	response to stress
BC1002_RS30295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC1002_RS30305	COG0589	response to stress
BC1002_RS30340	COG4566	intracellular signal transduction
BC1002_RS30365	COG0277	FAD linked oxidase domain protein
BC1002_RS30375	COG2721	sulfolactate sulfo-lyase activity
BC1002_RS30380	COG2271	Major facilitator Superfamily
BC1002_RS30385	COG0246	Mannitol dehydrogenase
BC1002_RS30390	COG1063	alcohol dehydrogenase
BC1002_RS30395	COG2186	Transcriptional regulator
BC1002_RS30400	COG1446	asparaginase
BC1002_RS30410	COG0583	DNA-binding transcription factor activity
BC1002_RS30415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BC1002_RS30420	COG0006	proline dipeptidase activity
BC1002_RS30435	COG3842	ATPase activity
BC1002_RS30440	COG0395	ABC-type sugar transport system, permease component
BC1002_RS30460	COG3158	transport of potassium into the cell
BC1002_RS30475	COG1131	(ABC) transporter
BC1002_RS30480	COG0842	Transport permease protein
BC1002_RS30490	COG3135	benzoate transporter
BC1002_RS30495	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS30500	COG0543	2 iron, 2 sulfur cluster binding
BC1002_RS30500	COG0633	Ferredoxin
BC1002_RS30505	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BC1002_RS30510	COG4638	Rieske (2fe-2S)
BC1002_RS30515	COG0583	DNA-binding transcription factor activity
BC1002_RS30530	COG4160	amino acid transport
BC1002_RS30580	COG3485	protocatechuate 3,4-dioxygenase
BC1002_RS30590	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS30605	COG0583	DNA-binding transcription factor activity
BC1002_RS30610	COG2814	Major facilitator Superfamily
BC1002_RS30620	COG1473	amidohydrolase
BC1002_RS30630	COG0583	DNA-binding transcription factor activity
BC1002_RS30645	COG2226	methyltransferase
BC1002_RS30650	COG1254	Belongs to the acylphosphatase family
BC1002_RS30680	COG0617	tRNA 3'-terminal CCA addition
BC1002_RS30680	COG0517	IMP dehydrogenase activity
BC1002_RS30680	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BC1002_RS30695	COG0494	nUDIX hydrolase
BC1002_RS30705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC1002_RS30710	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BC1002_RS30730	COG0346	lactoylglutathione lyase activity
BC1002_RS30760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC1002_RS30885	COG3188	usher protein
BC1002_RS30890	COG3121	Chaperone
BC1002_RS30925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC1002_RS30930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BC1002_RS30950	COG1192	Involved in chromosome partitioning
BC1002_RS30960	COG2610	gluconate transmembrane transporter activity
BC1002_RS30970	COG3791	Glutathione-dependent formaldehyde-activating
BC1002_RS30980	COG2205	protein histidine kinase activity
BC1002_RS30990	COG2235	arginine
BC1002_RS31000	COG2814	Major facilitator Superfamily
BC1002_RS31010	COG0477	Major facilitator Superfamily
BC1002_RS31015	COG0405	Gamma-glutamyltransferase
BC1002_RS31020	COG2186	Transcriptional regulator
BC1002_RS31025	COG3550	peptidyl-serine autophosphorylation
BC1002_RS31070	COG1609	Transcriptional regulator
BC1002_RS31075	COG1653	transport
BC1002_RS31080	COG1175	transmembrane transport
BC1002_RS31085	COG0395	ABC-type sugar transport system, permease component
BC1002_RS31095	COG3842	ATPase activity
BC1002_RS31115	COG1609	Transcriptional regulator
BC1002_RS31120	COG1653	transport
BC1002_RS31140	COG1472	Belongs to the glycosyl hydrolase 3 family
BC1002_RS31165	COG0129	dihydroxy-acid dehydratase activity
BC1002_RS31175	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS31215	COG1858	cytochrome C peroxidase
BC1002_RS31225	COG0651	ATP synthesis coupled electron transport
BC1002_RS31230	COG1006	Multisubunit Na H antiporter MnhC subunit
BC1002_RS31235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BC1002_RS31235	COG2111	Na H antiporter
BC1002_RS31255	COG1863	multisubunit Na H antiporter MnhE subunit
BC1002_RS31265	COG1993	acr, cog1993
BC1002_RS31285	COG0640	Transcriptional regulator
BC1002_RS31320	COG1609	Transcriptional regulator
BC1002_RS31325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC1002_RS31330	COG2271	Major facilitator Superfamily
BC1002_RS31335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC1002_RS31340	COG1309	transcriptional regulator
BC1002_RS31350	COG0493	'glutamate synthase
BC1002_RS31360	COG1953	Uracil, thiamine, allantoin
BC1002_RS31375	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BC1002_RS31415	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS31430	COG4993	Dehydrogenase
BC1002_RS31465	COG3546	catalase activity
BC1002_RS31475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BC1002_RS31475	COG1017	nitric oxide dioxygenase activity
BC1002_RS31495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BC1002_RS31510	COG0243	molybdopterin cofactor binding
BC1002_RS31525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BC1002_RS31535	COG0583	DNA-binding transcription factor activity
BC1002_RS31540	COG3246	L-lysine catabolic process to acetate
BC1002_RS31545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC1002_RS31585	COG1175	transmembrane transport
BC1002_RS31590	COG0395	ABC-type sugar transport system, permease component
BC1002_RS31600	COG3842	ATPase activity
BC1002_RS31605	COG3842	ATPase activity
BC1002_RS31615	COG2376	Dihydroxyacetone kinase
BC1002_RS31645	COG1280	lysine exporter protein (LysE YggA)
BC1002_RS31650	COG1064	alcohol dehydrogenase
BC1002_RS31680	COG4977	sequence-specific DNA binding
BC1002_RS31680	COG1917	Cupin 2, conserved barrel domain protein
BC1002_RS31685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC1002_RS31695	COG0628	permease
BC1002_RS31705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BC1002_RS31710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC1002_RS31735	COG0318	PFAM AMP-dependent synthetase and ligase
BC1002_RS31740	COG3047	cAMP biosynthetic process
BC1002_RS31800	COG2116	formate transmembrane transporter activity
BC1002_RS31820	COG3685	Protein conserved in bacteria
BC1002_RS31835	COG1672	PFAM Archaeal ATPase
BC1002_RS31835	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BC1002_RS31870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC1002_RS31885	COG0463	Glycosyl transferase, family 2
BC1002_RS31890	COG2192	nodulation
BC1002_RS31895	COG0859	PFAM glycosyl transferase family 9
BC1002_RS31900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BC1002_RS31905	COG0438	transferase activity, transferring glycosyl groups
BC1002_RS31910	COG5265	(ABC) transporter
BC1002_RS31930	COG0688	phosphatidylethanolamine metabolic process
BC1002_RS31940	COG2201	protein-glutamate methylesterase activity
BC1002_RS31950	COG0297	glycogen (starch) synthase activity
BC1002_RS31975	COG1546	Belongs to the CinA family
BC1002_RS31975	COG1058	Belongs to the CinA family
BC1002_RS31980	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BC1002_RS31990	COG3263	regulation of cellular component size
BC1002_RS31995	COG1764	response to oxidative stress
BC1002_RS32020	COG2244	polysaccharide biosynthetic process
BC1002_RS32025	COG0562	UDP-galactopyranose mutase
BC1002_RS32040	COG1216	Glycosyl transferase, family 2
BC1002_RS32045	COG2271	Major facilitator Superfamily
BC1002_RS32055	COG4948	Mandelate Racemase Muconate Lactonizing
BC1002_RS32085	COG0366	Alpha amylase catalytic
BC1002_RS32170	COG0583	DNA-binding transcription factor activity
BC1002_RS32255	COG5410	chromosome segregation
BC1002_RS32260	COG3567	Phage-associated protein, HI1409 family
BC1002_RS32265	COG2369	cell adhesion
BC1002_RS32405	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
BC1002_RS32415	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS32420	COG0583	DNA-binding transcription factor activity
BC1002_RS32545	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC1002_RS32555	COG1573	uracil-dna glycosylase
BC1002_RS32565	COG2814	Major facilitator Superfamily
BC1002_RS32570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC1002_RS32575	COG1464	Belongs to the NlpA lipoprotein family
BC1002_RS32585	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BC1002_RS32590	COG2010	Cytochrome c
BC1002_RS32610	COG4166	transmembrane transport
BC1002_RS32615	COG2271	Major facilitator Superfamily
BC1002_RS32680	COG1252	NADH dehydrogenase
BC1002_RS32685	COG1902	pentaerythritol trinitrate reductase activity
BC1002_RS32695	COG0583	DNA-binding transcription factor activity
BC1002_RS32700	COG0583	DNA-binding transcription factor activity
BC1002_RS32715	COG0300	oxidoreductase activity
BC1002_RS32725	COG1283	sodium-dependent phosphate transmembrane transporter activity
BC1002_RS32750	COG1012	belongs to the aldehyde dehydrogenase family
BC1002_RS32760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BC1002_RS32805	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BC1002_RS32805	COG1672	PFAM Archaeal ATPase
BC1002_RS32810	COG2313	pseudouridylate synthase activity
BC1002_RS32830	COG1902	pentaerythritol trinitrate reductase activity
BC1002_RS32835	COG0583	DNA-binding transcription factor activity
BC1002_RS32845	COG0004	ammonium transporteR
BC1002_RS32865	COG3284	Transcriptional regulator
BC1002_RS32870	COG3199	ATP-NAD kinase
BC1002_RS32875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BC1002_RS32880	COG0022	dehydrogenase e1 component
BC1002_RS32890	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BC1002_RS32910	COG1301	dicarboxylic acid transport
BC1002_RS32915	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BC1002_RS32925	COG0252	asparaginase activity
BC1002_RS32930	COG5002	protein histidine kinase activity
BC1002_RS32960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC1002_RS32980	COG3848	Pyruvate phosphate dikinase
BC1002_RS32980	COG0574	Belongs to the PEP-utilizing enzyme family
BC1002_RS33000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC1002_RS33015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BC1002_RS33020	COG3033	Beta-eliminating lyase
BC1002_RS33025	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BC1002_RS33035	COG1522	sequence-specific DNA binding
BC1002_RS33050	COG1448	Aminotransferase
BC1002_RS33060	COG2205	protein histidine kinase activity
BC1002_RS33065	COG0583	DNA-binding transcription factor activity
BC1002_RS33070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC1002_RS33115	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC1002_RS33120	COG0183	Belongs to the thiolase family
BC1002_RS33130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BC1002_RS33135	COG2151	metal-sulfur cluster biosynthetic enzyme
BC1002_RS33140	COG3396	Phenylacetate-CoA oxygenase
BC1002_RS33145	COG3460	Phenylacetate-CoA oxygenase
BC1002_RS33150	COG3396	Phenylacetate-CoA oxygenase
BC1002_RS33155	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BC1002_RS33165	COG2197	response regulator
BC1002_RS33190	COG0589	response to stress
BC1002_RS33210	COG2831	hemolysin activation secretion protein
BC1002_RS33260	COG3604	Transcriptional regulator
BC1002_RS33280	COG5002	protein histidine kinase activity
BC1002_RS33280	COG0784	Response regulator, receiver
BC1002_RS33300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC1002_RS33320	COG0071	Belongs to the small heat shock protein (HSP20) family
BC1002_RS33345	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BC1002_RS33345	COG2010	Cytochrome c
BC1002_RS33350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BC1002_RS33380	COG0629	single-stranded DNA binding
BC1002_RS33455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BC1002_RS33500	COG3504	Conjugal transfer protein
BC1002_RS33520	COG1192	Involved in chromosome partitioning
BC1002_RS33525	COG1475	DNA binding
BC1002_RS33550	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BC1002_RS33580	COG4974	Belongs to the 'phage' integrase family
BC1002_RS33675	COG3436	PFAM IS66 Orf2 family protein
BC1002_RS33700	COG1484	DNA-dependent DNA replication
BC1002_RS33705	COG4584	PFAM Integrase catalytic
BC1002_RS33755	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC1002_RS33780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC1002_RS33785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BC1002_RS33795	COG0529	Catalyzes the synthesis of activated sulfate
BC1002_RS33805	COG0500	methyltransferase
BC1002_RS33810	COG3153	acetyltransferase
BC1002_RS33850	COG0583	DNA-binding transcription factor activity
BC1002_RS33860	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BC1002_RS33865	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BC1002_RS33875	COG5420	small protein containing a coiled-coil domain
BC1002_RS33880	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
BC1002_RS33895	COG4584	PFAM Integrase catalytic
BC1002_RS33900	COG1484	DNA-dependent DNA replication
BC1002_RS33945	COG3436	PFAM IS66 Orf2 family protein
BC1002_RS33965	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BC1002_RS34000	COG5554	nitrogen fixation
BC1002_RS34010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BC1002_RS34045	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BC1002_RS34050	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BC1002_RS34055	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BC1002_RS34060	COG3047	cAMP biosynthetic process
BC1002_RS34080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BC1002_RS34100	COG2197	response regulator
BC1002_RS34110	COG0667	Aldo Keto reductase
BC1002_RS34130	COG3039	Transposase
BC1002_RS34150	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BC1002_RS34170	COG1473	amidohydrolase
BC1002_RS34185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC1002_RS34195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC1002_RS34300	COG3468	outer membrane autotransporter barrel domain protein
BC1002_RS34320	COG2801	Transposase and inactivated derivatives
BC1002_RS34335	COG2801	Transposase and inactivated derivatives
BC1002_RS34380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BC1002_RS34385	COG0840	transmembrane signaling receptor activity
BC1002_RS34405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BC1002_RS34405	COG0543	2 iron, 2 sulfur cluster binding
BC1002_RS34410	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BC1002_RS34415	COG4638	Rieske (2fe-2S)
BC1002_RS34495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BC1002_RS34500	COG1484	DNA-dependent DNA replication
BC1002_RS34505	COG4584	PFAM Integrase catalytic
BC1002_RS34610	COG2091	lysine biosynthetic process via aminoadipic acid
BC1002_RS34640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BC1002_RS34660	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BC1002_RS34665	COG2801	Transposase and inactivated derivatives
BC1002_RS34710	COG3039	Transposase
BC1002_RS34715	COG1028	Short-chain dehydrogenase reductase Sdr
BC1002_RS34735	COG3618	amidohydrolase
BC1002_RS34745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC1002_RS34750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC1002_RS34870	COG2205	protein histidine kinase activity
BC1002_RS34875	COG4974	Belongs to the 'phage' integrase family
BC1002_RS34910	COG2199	diguanylate cyclase activity
BC1002_RS34910	COG2200	EAL domain
BC1002_RS34910	COG2202	Pas domain
BC1002_RS34960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BC1002_RS35080	COG2336	PFAM SpoVT AbrB
BC1002_RS35085	COG4974	Belongs to the 'phage' integrase family
BC1002_RS35105	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BC1002_RS35145	COG1999	signal sequence binding
BC1002_RS35150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC1002_RS35155	COG3474	cytochrome
BC1002_RS35160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC1002_RS35195	COG4232	protein-disulfide reductase activity
BC1002_RS35205	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC1002_RS35210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BC1002_RS35300	COG0210	DNA helicase
BC1002_RS35350	COG3451	type IV secretory pathway VirB4
BC1002_RS35480	COG1475	DNA binding
BC1002_RS35575	COG5001	Diguanylate cyclase
BC1002_RS35575	COG2203	Gaf domain
BC1002_RS35575	COG3706	GGDEF domain
BC1002_RS35575	COG4251	negative regulation of phosphorylation
BC1002_RS35740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC1002_RS35990	COG0204	Acyl-transferase
BC1002_RS36095	COG5487	UPF0391 membrane protein
BC1002_RS36275	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BC1002_RS36315	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BC1002_RS36390	COG1942	4-Oxalocrotonate Tautomerase
BC1002_RS36570	COG0745	RESPONSE REGULATOR receiver
BC1002_RS36610	COG2337	Toxic component of a toxin-antitoxin (TA) module
BC1002_RS36620	COG0625	glutathione transferase activity
BC1002_RS36660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BC1002_RS36670	COG1773	rubredoxin
BC1002_RS36995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BC1002_RS37015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC1002_RS37175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BC1002_RS37360	COG0644	oxidoreductase
BC1002_RS37370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released