locus-tag	class	description
A4203_RS00005	COG1494	fructose-1,6-bisphosphatase
A4203_RS00080	COG1739	Uncharacterized protein family UPF0029
A4203_RS00085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A4203_RS00130	COG2853	Lipoprotein
A4203_RS00165	COG4942	peptidase
A4203_RS00170	COG2861	carbohydrate metabolic process
A4203_RS00185	COG0606	chelatase, subunit chli
A4203_RS00195	COG2990	Protein conserved in bacteria
A4203_RS00200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A4203_RS00215	COG0742	ribosomal rna small subunit methyltransferase
A4203_RS00235	COG0552	protein localization to endoplasmic reticulum
A4203_RS00240	COG2884	Cell division ATP-binding protein ftsE
A4203_RS00245	COG2177	Part of the ABC transporter FtsEX involved in
A4203_RS00290	COG1012	belongs to the aldehyde dehydrogenase family
A4203_RS00295	COG3384	dioxygenase
A4203_RS00305	COG2814	Major facilitator Superfamily
A4203_RS00310	COG3971	2-oxopent-4-enoate hydratase activity
A4203_RS00335	COG0494	nUDIX hydrolase
A4203_RS00340	COG1011	Hydrolase
A4203_RS00345	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A4203_RS00355	COG1218	3'(2'),5'-bisphosphate nucleotidase
A4203_RS00360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A4203_RS00365	COG0363	glucosamine-6-phosphate deaminase activity
A4203_RS00370	COG0625	glutathione transferase activity
A4203_RS00395	COG1040	competence protein
A4203_RS00405	COG3070	regulator of competence-specific genes
A4203_RS00445	COG1215	transferase activity, transferring glycosyl groups
A4203_RS00450	COG0569	domain protein
A4203_RS00460	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
A4203_RS00480	COG2841	Protein conserved in bacteria
A4203_RS00485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A4203_RS00500	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A4203_RS00505	COG1522	sequence-specific DNA binding
A4203_RS00530	COG2358	TRAP transporter, solute receptor (TAXI family
A4203_RS00545	COG2095	MarC family integral membrane protein
A4203_RS00550	COG0488	(ABC) transporter
A4203_RS00560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A4203_RS00565	COG0471	metal ion transport
A4203_RS00570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A4203_RS00575	COG1275	C4-dicarboxylate transporter malic acid transport protein
A4203_RS00595	COG3850	Histidine kinase
A4203_RS00600	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A4203_RS00605	COG3062	negative regulation of establishment of protein localization
A4203_RS00615	COG0437	4 iron, 4 sulfur cluster binding
A4203_RS00620	COG0348	domain, Protein
A4203_RS00625	COG3043	anaerobic respiration
A4203_RS00630	COG3005	denitrification pathway
A4203_RS00635	COG0758	DNA mediated transformation
A4203_RS00645	COG2818	Glycosylase
A4203_RS00670	COG0538	isocitrate dehydrogenase activity
A4203_RS00705	COG1238	metal cluster binding
A4203_RS00710	COG4942	peptidase
A4203_RS00710	COG1388	LysM domain
A4203_RS00735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A4203_RS00770	COG1794	racemase activity, acting on amino acids and derivatives
A4203_RS00775	COG3978	acetolactate synthase activity
A4203_RS00785	COG0561	phosphatase activity
A4203_RS00795	COG2267	carboxylic ester hydrolase activity
A4203_RS00800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A4203_RS00810	COG0561	phosphatase activity
A4203_RS00815	COG0235	Class ii aldolase
A4203_RS00820	COG3623	hexulose-6-phosphate isomerase
A4203_RS00825	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A4203_RS00850	COG1129	ABC transporter
A4203_RS00855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A4203_RS00860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A4203_RS00865	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A4203_RS00870	COG2731	YhcH YjgK YiaL family protein
A4203_RS00880	COG1414	Transcriptional regulator
A4203_RS00890	COG0477	Major facilitator Superfamily
A4203_RS00900	COG0351	phosphomethylpyrimidine kinase
A4203_RS00910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A4203_RS00915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A4203_RS00920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A4203_RS00925	COG1116	anion transmembrane transporter activity
A4203_RS00940	COG0551	DNA topoisomerase type I activity
A4203_RS00955	COG1070	Carbohydrate kinase
A4203_RS00960	COG2390	Transcriptional regulator
A4203_RS00965	COG1129	ABC transporter
A4203_RS01010	COG0583	DNA-binding transcription factor activity
A4203_RS01020	COG3956	TIGRFAM MazG family protein
A4203_RS01040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A4203_RS01055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A4203_RS01060	COG2364	Membrane
A4203_RS01065	COG0859	PFAM glycosyl transferase family 9
A4203_RS01090	COG3069	C4-dicarboxylate transmembrane transporter activity
A4203_RS01095	COG1473	amidohydrolase
A4203_RS01105	COG4772	TonB-dependent receptor
A4203_RS01115	COG1132	(ABC) transporter
A4203_RS01120	COG0859	PFAM glycosyl transferase family 9
A4203_RS01135	COG1519	Transferase
A4203_RS01140	COG0463	Glycosyl transferase, family 2
A4203_RS01145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A4203_RS01150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A4203_RS01155	COG1120	ATPase activity
A4203_RS01160	COG0500	methyltransferase
A4203_RS01170	COG0456	acetyltransferase
A4203_RS01180	COG0762	integral membrane protein
A4203_RS01190	COG3171	Protein conserved in bacteria
A4203_RS01200	COG3038	cytochrome b561
A4203_RS01205	COG1194	a g-specific adenine glycosylase
A4203_RS01235	COG3056	Lipoprotein
A4203_RS01240	COG0271	Belongs to the BolA IbaG family
A4203_RS01245	COG1879	ABC-type sugar transport system periplasmic component
A4203_RS01250	COG1129	ABC transporter
A4203_RS01255	COG1172	Belongs to the binding-protein-dependent transport system permease family
A4203_RS01290	COG1477	protein flavinylation
A4203_RS01305	COG1230	cation diffusion facilitator family transporter
A4203_RS01310	COG2271	Major facilitator Superfamily
A4203_RS01320	COG2197	response regulator
A4203_RS01325	COG2271	Major facilitator Superfamily
A4203_RS01345	COG1309	transcriptional regulator
A4203_RS01350	COG0583	DNA-binding transcription factor activity
A4203_RS01355	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A4203_RS01355	COG0678	peroxiredoxin activity
A4203_RS01365	COG0545	Peptidyl-prolyl cis-trans isomerase
A4203_RS01370	COG2964	Protein conserved in bacteria
A4203_RS01385	COG2168	tRNA wobble position uridine thiolation
A4203_RS01410	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A4203_RS01430	COG1929	Belongs to the glycerate kinase type-1 family
A4203_RS01435	COG2610	gluconate transmembrane transporter activity
A4203_RS01470	COG3068	Protein conserved in bacteria
A4203_RS01550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A4203_RS01555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A4203_RS01560	COG0006	proline dipeptidase activity
A4203_RS01580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A4203_RS01595	COG1496	oxidoreductase activity
A4203_RS01615	COG1737	Transcriptional regulator
A4203_RS01620	COG2731	YhcH YjgK YiaL family protein
A4203_RS01655	COG4232	protein-disulfide reductase activity
A4203_RS01685	COG1011	Hydrolase
A4203_RS01695	COG0697	spore germination
A4203_RS01700	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A4203_RS01720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A4203_RS01730	COG0805	protein transport
A4203_RS01770	COG1368	sulfuric ester hydrolase activity
A4203_RS01775	COG3119	arylsulfatase activity
A4203_RS01795	COG0641	radical SAM
A4203_RS01800	COG1253	flavin adenine dinucleotide binding
A4203_RS01810	COG0084	hydrolase, TatD family'
A4203_RS01815	COG0470	DNA polymerase III
A4203_RS01825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A4203_RS01830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A4203_RS01840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A4203_RS01860	COG1555	photosystem II stabilization
A4203_RS01880	COG0196	riboflavin kinase activity
A4203_RS01885	COG0728	peptidoglycan biosynthetic process
A4203_RS01905	COG0560	Phosphoserine phosphatase
A4203_RS01925	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A4203_RS01925	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A4203_RS01935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A4203_RS01945	COG2376	Dihydroxyacetone kinase
A4203_RS01950	COG1461	Dihydroxyacetone kinase
A4203_RS01960	COG2390	Transcriptional regulator
A4203_RS01965	COG0698	ribose 5-phosphate isomerase
A4203_RS01970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A4203_RS01980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A4203_RS02005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A4203_RS02035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A4203_RS02040	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A4203_RS02055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A4203_RS02060	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A4203_RS02065	COG4972	Pilus assembly protein
A4203_RS02085	COG4796	Type ii and iii secretion system protein
A4203_RS02100	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A4203_RS02105	COG4701	Protein of unknown function (DUF721)
A4203_RS02120	COG0494	nUDIX hydrolase
A4203_RS02130	COG1466	dna polymerase III delta subunit
A4203_RS02135	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
A4203_RS02155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A4203_RS02165	COG2608	mercury ion transmembrane transporter activity
A4203_RS02175	COG1305	Transglutaminase-like
A4203_RS02190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A4203_RS02265	COG2226	methyltransferase
A4203_RS02275	COG0814	amino acid
A4203_RS02285	COG4783	chaperone-mediated protein folding
A4203_RS02300	COG0848	biopolymer transport protein
A4203_RS02305	COG0811	peptide transport
A4203_RS02310	COG4536	flavin adenine dinucleotide binding
A4203_RS02315	COG4137	Cytochrome C assembly protein
A4203_RS02320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A4203_RS02370	COG1217	gtp-binding protein TYPA
A4203_RS02375	COG3739	integral membrane protein
A4203_RS02385	COG1720	tRNA m6t6A37 methyltransferase activity
A4203_RS02390	COG1575	Belongs to the MenA family. Type 1 subfamily
A4203_RS02400	COG0471	metal ion transport
A4203_RS02435	COG0592	DNA-directed DNA polymerase activity
A4203_RS02445	COG2226	methyltransferase
A4203_RS02470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A4203_RS02500	COG3306	glycosyltransferase involved in LPS biosynthesis
A4203_RS02515	COG1216	Glycosyl transferase, family 2
A4203_RS02520	COG1442	glycosyl transferase family 8
A4203_RS02525	COG0438	transferase activity, transferring glycosyl groups
A4203_RS02530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A4203_RS02535	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A4203_RS02540	COG1309	transcriptional regulator
A4203_RS02545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A4203_RS02550	COG1956	GAF domain-containing protein
A4203_RS02555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A4203_RS02565	COG1393	Belongs to the ArsC family
A4203_RS02570	COG3036	rescue of stalled ribosome
A4203_RS02640	COG4785	May be involved in cell division
A4203_RS02645	COG0513	Belongs to the DEAD box helicase family
A4203_RS02655	COG3842	ATPase activity
A4203_RS02660	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A4203_RS02685	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A4203_RS02690	COG1027	Aspartate ammonia-lyase
A4203_RS02710	COG4545	Glutaredoxin-related protein
A4203_RS02740	COG0511	ligase activity, forming carbon-carbon bonds
A4203_RS02745	COG0439	Biotin carboxylase
A4203_RS02750	COG3924	membrane
A4203_RS02755	COG4145	pantothenate transmembrane transporter activity
A4203_RS02810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A4203_RS02815	COG4558	Periplasmic binding protein
A4203_RS02830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A4203_RS02855	COG3691	Protein conserved in bacteria
A4203_RS02865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A4203_RS02875	COG0861	Integral membrane protein TerC family
A4203_RS02885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A4203_RS02885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A4203_RS02890	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A4203_RS02895	COG3722	fumarate hydratase activity
A4203_RS02910	COG5645	(Lipo)protein
A4203_RS02915	COG0210	DNA helicase
A4203_RS02940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A4203_RS02950	COG1238	metal cluster binding
A4203_RS02965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A4203_RS02980	COG0697	spore germination
A4203_RS02990	COG0561	phosphatase activity
A4203_RS02995	COG1702	phosphate starvation-inducible protein PhoH
A4203_RS03010	COG1444	tRNA N-acetyltransferase activity
A4203_RS03020	COG2194	sulfuric ester hydrolase activity
A4203_RS03025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A4203_RS03030	COG4211	Belongs to the binding-protein-dependent transport system permease family
A4203_RS03040	COG1879	ABC-type sugar transport system periplasmic component
A4203_RS03045	COG1609	Transcriptional regulator
A4203_RS03050	COG1085	galactose-1-phosphate uridylyltransferase
A4203_RS03060	COG2017	converts alpha-aldose to the beta-anomer
A4203_RS03075	COG0305	Participates in initiation and elongation during chromosome replication
A4203_RS03105	COG0629	single-stranded DNA binding
A4203_RS03185	COG2132	Multicopper oxidase
A4203_RS03205	COG0667	Aldo Keto reductase
A4203_RS03225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A4203_RS03435	COG2826	transposase and inactivated derivatives, IS30 family
A4203_RS03480	COG1088	dTDP-glucose 4,6-dehydratase activity
A4203_RS03505	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A4203_RS03515	COG1393	Belongs to the ArsC family
A4203_RS03525	COG1876	peptidase activity
A4203_RS03530	COG0494	nUDIX hydrolase
A4203_RS03535	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A4203_RS03545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A4203_RS03550	COG1596	polysaccharide export
A4203_RS03560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A4203_RS03585	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A4203_RS03615	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A4203_RS03620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A4203_RS03645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A4203_RS03670	COG0626	cystathionine gamma-synthase activity
A4203_RS03690	COG1530	ribonuclease E activity
A4203_RS03705	COG2056	Na+-H+ antiporter family
A4203_RS03715	COG0346	lactoylglutathione lyase activity
A4203_RS03730	COG1755	Isoprenylcysteine carboxyl methyltransferase
A4203_RS03745	COG0494	nUDIX hydrolase
A4203_RS03780	COG1271	oxidase subunit
A4203_RS03785	COG1294	oxidase, subunit
A4203_RS03800	COG0824	Thioesterase
A4203_RS03805	COG0811	peptide transport
A4203_RS03810	COG0848	biopolymer transport protein
A4203_RS03815	COG3064	Membrane
A4203_RS03845	COG2165	general secretion pathway protein
A4203_RS03850	COG4795	General secretion pathway protein
A4203_RS03865	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A4203_RS03870	COG0456	acetyltransferase
A4203_RS03875	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
A4203_RS03895	COG1840	ABC-type Fe3 transport system, periplasmic component
A4203_RS03905	COG1840	ABC-type Fe3 transport system, periplasmic component
A4203_RS03935	COG0659	secondary active sulfate transmembrane transporter activity
A4203_RS03940	COG0800	Aldolase
A4203_RS03955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A4203_RS03960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A4203_RS03965	COG0084	hydrolase, TatD family'
A4203_RS03980	COG1328	CTP reductase activity
A4203_RS03980	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A4203_RS03985	COG1858	cytochrome C peroxidase
A4203_RS03995	COG0527	aspartate kinase activity
A4203_RS04005	COG2860	membrane
A4203_RS04015	COG3069	C4-dicarboxylate transmembrane transporter activity
A4203_RS04035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A4203_RS04045	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
A4203_RS04050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A4203_RS04055	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
A4203_RS04060	COG1022	Amp-dependent synthetase and ligase
A4203_RS04070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A4203_RS04090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A4203_RS04150	COG0748	coenzyme F420 binding
A4203_RS04155	COG4771	TonB-dependent receptor
A4203_RS04155	COG1629	transport
A4203_RS04165	COG0489	protein tyrosine kinase activity
A4203_RS04200	COG1518	maintenance of DNA repeat elements
A4203_RS04210	COG0784	Response regulator, receiver
A4203_RS04210	COG2198	Histidine kinase
A4203_RS04210	COG5002	protein histidine kinase activity
A4203_RS04225	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A4203_RS04230	COG1959	2 iron, 2 sulfur cluster binding
A4203_RS04240	COG0822	iron-sulfur transferase activity
A4203_RS04245	COG0316	Belongs to the HesB IscA family
A4203_RS04260	COG0633	Ferredoxin
A4203_RS04275	COG0741	lytic transglycosylase activity
A4203_RS04280	COG2350	Protein conserved in bacteria
A4203_RS04285	COG1607	acyl-coa hydrolase
A4203_RS04305	COG0497	DNA recombination
A4203_RS04320	COG1823	symporter activity
A4203_RS04335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A4203_RS04345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A4203_RS04350	COG1530	ribonuclease E activity
A4203_RS04370	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A4203_RS04375	COG0142	geranyltranstransferase activity
A4203_RS04390	COG0697	spore germination
A4203_RS04395	COG0697	spore germination
A4203_RS04405	COG0735	belongs to the Fur family
A4203_RS04410	COG0716	FMN binding
A4203_RS04420	COG0596	Alpha beta hydrolase
A4203_RS04425	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
A4203_RS04430	COG0318	PFAM AMP-dependent synthetase and ligase
A4203_RS04435	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
A4203_RS04435	COG3264	Mechanosensitive ion channel
A4203_RS04445	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
A4203_RS04450	COG0730	response to heat
A4203_RS04455	COG1560	Kdo2-lipid A biosynthetic process
A4203_RS04465	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A4203_RS04475	COG0251	oxidation-reduction process
A4203_RS04490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A4203_RS04495	COG0187	DNA topoisomerase II activity
A4203_RS04500	COG0019	diaminopimelate decarboxylase activity
A4203_RS04515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A4203_RS04515	COG4797	methyltransferase
A4203_RS04525	COG4143	(ABC) transporter
A4203_RS04530	COG1178	ABC-type Fe3 transport system permease component
A4203_RS04545	COG0733	neurotransmitter:sodium symporter activity
A4203_RS04550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A4203_RS04605	COG1289	transmembrane transporter activity
A4203_RS04610	COG3304	Inner membrane component domain
A4203_RS04630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A4203_RS04635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A4203_RS04640	COG1121	(ABC) transporter
A4203_RS04650	COG2920	part of a sulfur-relay system
A4203_RS04670	COG2864	formate dehydrogenase
A4203_RS04675	COG0437	4 iron, 4 sulfur cluster binding
A4203_RS04680	COG0243	molybdopterin cofactor binding
A4203_RS04680	COG3383	formate dehydrogenase (NAD+) activity
A4203_RS04685	COG3383	formate dehydrogenase (NAD+) activity
A4203_RS04685	COG0243	molybdopterin cofactor binding
A4203_RS04695	COG0210	DNA helicase
A4203_RS04710	COG0463	Glycosyl transferase, family 2
A4203_RS04745	COG0583	DNA-binding transcription factor activity
A4203_RS04755	COG0488	(ABC) transporter
A4203_RS04760	COG3683	transport system, periplasmic component
A4203_RS04765	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
A4203_RS04790	COG5002	protein histidine kinase activity
A4203_RS04795	COG0745	RESPONSE REGULATOR receiver
A4203_RS04825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A4203_RS04830	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A4203_RS04840	COG2062	phosphohistidine phosphatase, SixA
A4203_RS04870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A4203_RS04875	COG4181	ATPase activity
A4203_RS04885	COG1136	(ABC) transporter
A4203_RS04885	COG0577	efflux transmembrane transporter activity
A4203_RS04900	COG0672	)-iron permease
A4203_RS04910	COG2837	iron assimilation
A4203_RS04915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A4203_RS04930	COG0024	Methionine aminopeptidase
A4203_RS05000	COG2431	L-lysine efflux transmembrane transporter activity
A4203_RS05005	COG3593	DNA synthesis involved in DNA repair
A4203_RS05020	COG3101	peptidyl-lysine hydroxylation
A4203_RS05030	COG0842	Transport permease protein
A4203_RS05035	COG2358	TRAP transporter, solute receptor (TAXI family
A4203_RS05050	COG1611	Belongs to the LOG family
A4203_RS05060	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
A4203_RS05065	COG3098	single-species biofilm formation
A4203_RS05090	COG1067	ATP-dependent peptidase activity
A4203_RS05100	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A4203_RS05105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A4203_RS05185	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A4203_RS05200	COG3306	glycosyltransferase involved in LPS biosynthesis
A4203_RS05210	COG1216	Glycosyl transferase, family 2
A4203_RS05215	COG1216	Glycosyl transferase, family 2
A4203_RS05220	COG2951	lytic endotransglycosylase activity
A4203_RS05225	COG2252	PERMEase
A4203_RS05230	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A4203_RS05235	COG1074	ATP-dependent DNA helicase activity
A4203_RS05240	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A4203_RS05245	COG2999	glutathione oxidoreductase activity
A4203_RS05270	COG2969	positive regulation of protein catabolic process
A4203_RS05275	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A4203_RS05280	COG0517	IMP dehydrogenase activity
A4203_RS05280	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A4203_RS05295	COG1538	Outer membrane efflux protein
A4203_RS05305	COG1115	amino acid carrier protein
A4203_RS05325	COG0142	geranyltranstransferase activity
A4203_RS05335	COG0243	molybdopterin cofactor binding
A4203_RS05340	COG3005	denitrification pathway
A4203_RS05370	COG1640	4-alpha-glucanotransferase
A4203_RS05380	COG1523	belongs to the glycosyl hydrolase 13 family
A4203_RS05410	COG1090	epimerase
A4203_RS05430	COG3102	Protein conserved in bacteria
A4203_RS05440	COG3133	Outer membrane lipoprotein
A4203_RS05465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A4203_RS05470	COG4591	ABC-type transport system involved in lipoprotein release permease component
A4203_RS05480	COG4591	ABC-type transport system involved in lipoprotein release permease component
A4203_RS05485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A4203_RS05495	COG0402	S-adenosylhomocysteine deaminase activity
A4203_RS05500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A4203_RS05505	COG0583	DNA-binding transcription factor activity
A4203_RS05515	COG2833	Protein of unknown function (DUF455)
A4203_RS05520	COG1946	Acyl-CoA thioesterase
A4203_RS05530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A4203_RS05535	COG4988	ABC transporter
A4203_RS05540	COG0492	ferredoxin-NADP+ reductase activity
A4203_RS05545	COG3118	belongs to the thioredoxin family
A4203_RS05550	COG0288	reversible hydration of carbon dioxide
A4203_RS05555	COG1629	transport
A4203_RS05570	COG4221	oxidoreductase activity
A4203_RS05590	COG0512	Glutamine amidotransferase of anthranilate synthase
A4203_RS05595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A4203_RS05600	COG0616	signal peptide processing
A4203_RS05615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A4203_RS05635	COG0747	negative chemotaxis
A4203_RS05645	COG0730	response to heat
A4203_RS05650	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A4203_RS05655	COG3119	arylsulfatase activity
A4203_RS05660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A4203_RS05665	COG0641	radical SAM
A4203_RS05670	COG0676	glucose-6-phosphate 1-epimerase activity
A4203_RS05680	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A4203_RS05720	COG0697	spore germination
A4203_RS05725	COG2925	Exonuclease
A4203_RS05730	COG4575	ribosome binding
A4203_RS05750	COG0613	PHP domain protein
A4203_RS05760	COG0308	aminopeptidase N
A4203_RS05765	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A4203_RS05770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A4203_RS05775	COG1448	Aminotransferase
A4203_RS05785	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A4203_RS05805	COG0791	NLP P60 protein
A4203_RS05835	COG0564	pseudouridine synthase activity
A4203_RS05840	COG0406	alpha-ribazole phosphatase activity
A4203_RS05845	COG0285	dihydrofolate synthase activity
A4203_RS05870	COG0586	Pfam SNARE associated Golgi protein
A4203_RS05880	COG1940	carbohydrate kinase activity
A4203_RS05890	COG4953	penicillin-binding protein 1C
A4203_RS05910	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A4203_RS05915	COG2823	Periplasmic or secreted lipoprotein
A4203_RS05920	COG0307	riboflavin synthase, alpha
A4203_RS05930	COG0673	inositol 2-dehydrogenase activity
A4203_RS05935	COG0469	pyruvate kinase activity
A4203_RS05970	COG0583	DNA-binding transcription factor activity
A4203_RS05980	COG0009	L-threonylcarbamoyladenylate synthase
A4203_RS05985	COG4409	exo-alpha-(2->6)-sialidase activity
A4203_RS05990	COG0287	Prephenate dehydrogenase
A4203_RS05990	COG1605	Chorismate mutase
A4203_RS05995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A4203_RS06000	COG1528	Iron-storage protein
A4203_RS06005	COG1528	Iron-storage protein
A4203_RS06015	COG0589	response to stress
A4203_RS06025	COG0616	signal peptide processing
A4203_RS06030	COG0778	Nitroreductase
A4203_RS06035	COG0515	serine threonine protein kinase
A4203_RS06050	COG0671	phosphoesterase, PA-phosphatase related
A4203_RS06060	COG4166	transmembrane transport
A4203_RS06065	COG2832	Protein of unknown function (DUF454)
A4203_RS06070	COG0339	signal peptide processing
A4203_RS06100	COG1940	carbohydrate kinase activity
A4203_RS06100	COG1846	Transcriptional regulator
A4203_RS06115	COG2226	methyltransferase
A4203_RS06120	COG1944	ATP diphosphatase activity
A4203_RS06125	COG3105	Protein conserved in bacteria
A4203_RS06135	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
A4203_RS06140	COG0708	Exodeoxyribonuclease III
A4203_RS06155	COG0303	'Molybdopterin
A4203_RS06160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A4203_RS06165	COG0163	prenyltransferase activity
A4203_RS06175	COG1286	toxin biosynthetic process
A4203_RS06190	COG0280	phosphate acetyltransferase
A4203_RS06190	COG0857	belongs to the CobB CobQ family
A4203_RS06195	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A4203_RS06200	COG0318	PFAM AMP-dependent synthetase and ligase
A4203_RS06205	COG3065	identical protein binding
A4203_RS06210	COG1214	PFAM Peptidase M22, glycoprotease
A4203_RS06215	COG1199	ATP-dependent helicase activity
A4203_RS06220	COG0676	glucose-6-phosphate 1-epimerase activity
A4203_RS06230	COG1534	Rna-binding protein
A4203_RS06245	COG2027	D-alanyl-D-alanine carboxypeptidase
A4203_RS06250	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A4203_RS06255	COG0733	neurotransmitter:sodium symporter activity
A4203_RS06265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A4203_RS06270	COG0633	Ferredoxin
A4203_RS06290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A4203_RS06325	COG1280	lysine exporter protein (LysE YggA)
A4203_RS06330	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A4203_RS06335	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A4203_RS06350	COG0814	amino acid
A4203_RS06355	COG0778	Nitroreductase
A4203_RS06360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A4203_RS06365	COG5339	Protein conserved in bacteria
A4203_RS06395	COG1629	transport
A4203_RS06395	COG4771	TonB-dependent receptor
A4203_RS06405	COG4149	molybdate abc transporter
A4203_RS06410	COG0725	ABC transporter, periplasmic molybdate-binding protein
A4203_RS06420	COG2005	Transcriptional regulator
A4203_RS06430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A4203_RS06435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A4203_RS06435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A4203_RS06450	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A4203_RS06455	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A4203_RS06500	COG0195	Participates in both transcription termination and antitermination
A4203_RS06535	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A4203_RS06555	COG1643	Atp-dependent helicase
A4203_RS06560	COG2363	Small membrane protein
A4203_RS06595	COG0463	Glycosyl transferase, family 2
A4203_RS06625	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
A4203_RS06635	COG1704	LemA family
A4203_RS06640	COG2885	chlorophyll binding
A4203_RS06640	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A4203_RS06645	COG0277	FAD linked oxidase domain protein
A4203_RS06645	COG0247	lactate metabolic process
A4203_RS06665	COG3265	gluconokinase activity
A4203_RS06670	COG1609	Transcriptional regulator
A4203_RS06675	COG1063	alcohol dehydrogenase
A4203_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
A4203_RS06685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A4203_RS06695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A4203_RS06695	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A4203_RS06700	COG0626	cystathionine gamma-synthase activity
A4203_RS06705	COG0450	alkyl hydroperoxide reductase
A4203_RS06710	COG0023	Translation Initiation Factor
A4203_RS06720	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
A4203_RS06725	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
A4203_RS06735	COG0539	negative regulation of cytoplasmic translation
A4203_RS06745	COG4771	TonB-dependent receptor
A4203_RS06750	COG0612	Peptidase, M16
A4203_RS06760	COG1982	Orn Lys Arg decarboxylase major
A4203_RS06765	COG0531	amino acid
A4203_RS06775	COG2990	Protein conserved in bacteria
A4203_RS06780	COG0814	amino acid
A4203_RS06800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A4203_RS06820	COG0783	Belongs to the Dps family
A4203_RS06850	COG2927	DNA polymerase III (CHI subunit)
A4203_RS06860	COG2268	Band 7 protein
A4203_RS06875	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A4203_RS06900	COG3716	PTS system mannose fructose sorbose family IID component
A4203_RS06905	COG3715	PTS system
A4203_RS06910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A4203_RS06910	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A4203_RS06915	COG2814	Major facilitator Superfamily
A4203_RS06945	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A4203_RS06950	COG3094	Invasion gene expression up-regulator, SirB
A4203_RS07000	COG1450	Type ii and iii secretion system protein
A4203_RS07035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A4203_RS07065	COG0658	competence protein
A4203_RS07065	COG2333	competence protein COMEC
A4203_RS07075	COG0617	tRNA 3'-terminal CCA addition
A4203_RS07080	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A4203_RS07090	COG2949	membrane
A4203_RS07100	COG0440	acetolactate synthase activity
A4203_RS07105	COG0028	Belongs to the TPP enzyme family
A4203_RS07110	COG1757	Na H antiporter
A4203_RS07115	COG2916	Histone family protein nucleoid-structuring protein H-NS
A4203_RS07120	COG0788	formyltetrahydrofolate deformylase activity
A4203_RS07125	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A4203_RS07140	COG2190	(PTS) system
A4203_RS07140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A4203_RS07140	COG1263	PTS System
A4203_RS07145	COG0488	(ABC) transporter
A4203_RS07155	COG1346	cytolysis
A4203_RS07165	COG1525	nuclease
A4203_RS07175	COG2166	iron-sulfur cluster assembly
A4203_RS07185	COG1560	Kdo2-lipid A biosynthetic process
A4203_RS07190	COG3381	protein complex oligomerization
A4203_RS07195	COG2249	NAD(P)H dehydrogenase (quinone) activity
A4203_RS07205	COG0330	HflC and HflK could
A4203_RS07210	COG1119	ATPase activity
A4203_RS07220	COG2932	Transcriptional regulator
A4203_RS07225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A4203_RS07230	COG0508	dehydrogenase complex catalyzes the overall conversion of
A4203_RS07235	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A4203_RS07240	COG2190	(PTS) system
A4203_RS07245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A4203_RS07250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A4203_RS07275	COG0802	atpase or kinase
A4203_RS07280	COG0860	N-Acetylmuramoyl-L-alanine amidase
A4203_RS07280	COG1388	LysM domain
A4203_RS07300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A4203_RS07305	COG3283	Transcriptional regulator of aromatic amino acids metabolism
A4203_RS07315	COG3106	COG3106 Predicted ATPase
A4203_RS07320	COG4166	transmembrane transport
A4203_RS07325	COG4168	peptide transport system, permease
A4203_RS07330	COG4171	peptide transport system, permease
A4203_RS07335	COG4172	Belongs to the ABC transporter superfamily
A4203_RS07340	COG4172	Belongs to the ABC transporter superfamily
A4203_RS07375	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A4203_RS07375	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A4203_RS07425	COG2252	PERMEase
A4203_RS07435	COG2814	Major facilitator Superfamily
A4203_RS07445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A4203_RS07460	COG0508	dehydrogenase complex catalyzes the overall conversion of
A4203_RS07465	COG0567	Dehydrogenase, E1 component
A4203_RS07490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A4203_RS07495	COG3108	Peptidase M15
A4203_RS07500	COG2989	Protein conserved in bacteria
A4203_RS07505	COG0793	Belongs to the peptidase S41A family
A4203_RS07515	COG2995	paraquat-inducible protein a
A4203_RS07520	COG3008	intermembrane lipid transfer
A4203_RS07535	COG1176	ABC-type spermidine putrescine transport system, permease component I
A4203_RS07540	COG1177	transmembrane transport
A4203_RS07545	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A4203_RS07550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A4203_RS07565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A4203_RS07580	COG1522	sequence-specific DNA binding
A4203_RS07590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A4203_RS07595	COG3025	triphosphatase activity
A4203_RS07600	COG1392	Phosphate transport regulator
A4203_RS07605	COG0306	phosphate transporter
A4203_RS07610	COG4991	sh3 domain protein
A4203_RS07635	COG0739	heme binding
A4203_RS07645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A4203_RS07650	COG4608	Belongs to the ABC transporter superfamily
A4203_RS07655	COG0444	Belongs to the ABC transporter superfamily
A4203_RS07660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A4203_RS07665	COG0601	transmembrane transport
A4203_RS07670	COG0747	negative chemotaxis
A4203_RS07675	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A4203_RS07685	COG0826	peptidase U32
A4203_RS07705	COG0561	phosphatase activity
A4203_RS07710	COG3069	C4-dicarboxylate transmembrane transporter activity
A4203_RS07720	COG1862	Preprotein translocase
A4203_RS07725	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A4203_RS07730	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A4203_RS07765	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A4203_RS07770	COG0745	RESPONSE REGULATOR receiver
A4203_RS07785	COG3585	molybdate ion transport
A4203_RS07790	COG0642	Histidine kinase
A4203_RS07795	COG0745	RESPONSE REGULATOR receiver
A4203_RS07800	COG2259	Doxx family
A4203_RS07815	COG3219	Protein conserved in bacteria
A4203_RS07825	COG1595	DNA-templated transcription, initiation
A4203_RS07860	COG1840	ABC-type Fe3 transport system, periplasmic component
A4203_RS07870	COG1053	succinate dehydrogenase
A4203_RS07875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A4203_RS07890	COG0795	lipopolysaccharide-transporting ATPase activity
A4203_RS07895	COG0795	lipopolysaccharide-transporting ATPase activity
A4203_RS07910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A4203_RS07915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A4203_RS07940	COG1083	cytidylyl-transferase
A4203_RS07950	COG0720	synthase
A4203_RS07955	COG0602	queuosine metabolic process
A4203_RS07980	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A4203_RS07995	COG5007	Belongs to the BolA IbaG family
A4203_RS08000	COG3113	response to antibiotic
A4203_RS08005	COG2854	intermembrane phospholipid transfer
A4203_RS08010	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A4203_RS08015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A4203_RS08020	COG1127	ABC transporter
A4203_RS08025	COG3117	lipopolysaccharide transmembrane transporter activity
A4203_RS08030	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A4203_RS08035	COG1137	ATPase activity
A4203_RS08040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A4203_RS08055	COG2850	peptidyl-arginine hydroxylation
A4203_RS08065	COG2867	negative regulation of translational initiation
A4203_RS08080	COG0531	amino acid
A4203_RS08090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A4203_RS08095	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A4203_RS08100	COG2824	Alkylphosphonate utilization operon protein PhnA
A4203_RS08120	COG1172	Belongs to the binding-protein-dependent transport system permease family
A4203_RS08125	COG1879	ABC-type sugar transport system periplasmic component
A4203_RS08130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A4203_RS08140	COG1605	Chorismate mutase
A4203_RS08140	COG0077	Prephenate dehydratase
A4203_RS08145	COG1979	alcohol dehydrogenase
A4203_RS08155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A4203_RS08160	COG0849	cell division
A4203_RS08165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A4203_RS08200	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A4203_RS08210	COG0768	penicillin binding
A4203_RS08215	COG3116	cell division
A4203_RS08230	COG1966	Carbon starvation protein
A4203_RS08235	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A4203_RS08240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A4203_RS08245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A4203_RS08250	COG1120	ATPase activity
A4203_RS08260	COG4160	amino acid transport
A4203_RS08265	COG4215	(ABC) transporter
A4203_RS08270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A4203_RS08275	COG1126	abc transporter atp-binding protein
A4203_RS08285	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A4203_RS08290	COG0312	modulator of DNA gyrase
A4203_RS08300	COG0330	HflC and HflK could
A4203_RS08305	COG0330	HflC and HflK could
A4203_RS08315	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A4203_RS08325	COG0527	aspartate kinase activity
A4203_RS08325	COG0460	homoserine dehydrogenase
A4203_RS08410	COG0204	Acyl-transferase
A4203_RS08420	COG5413	integral membrane protein
A4203_RS08430	COG1509	lysine 2,3-aminomutase activity
A4203_RS08435	COG3061	Opacity-associated protein A
A4203_RS08435	COG3266	domain, Protein
A4203_RS08455	COG2814	Major facilitator Superfamily
A4203_RS08465	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A4203_RS08470	COG1115	amino acid carrier protein
A4203_RS08495	COG1459	type II secretion system
A4203_RS08500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A4203_RS08505	COG4969	Belongs to the N-Me-Phe pilin family
A4203_RS08510	COG3023	N-Acetylmuramoyl-L-alanine amidase
A4203_RS08520	COG0730	response to heat
A4203_RS08535	COG0590	tRNA wobble adenosine to inosine editing
A4203_RS08540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A4203_RS08550	COG1882	Formate acetyltransferase
A4203_RS08555	COG2116	formate transmembrane transporter activity
A4203_RS08560	COG0537	adenosine 5'-monophosphoramidase activity
A4203_RS08585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A4203_RS08615	COG0681	Belongs to the peptidase S26 family
A4203_RS08655	COG2267	carboxylic ester hydrolase activity
A4203_RS08670	COG0436	Aminotransferase
A4203_RS08685	COG3842	ATPase activity
A4203_RS08710	COG2095	MarC family integral membrane protein
A4203_RS08715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A4203_RS08720	COG0748	coenzyme F420 binding
A4203_RS08725	COG4178	(ABC) transporter
A4203_RS08740	COG0121	glutamine amidotransferase
A4203_RS08745	COG0814	amino acid
A4203_RS08750	COG1760	l-serine dehydratase
A4203_RS08755	COG3738	Protein conserved in bacteria
A4203_RS08765	COG0753	catalase activity
A4203_RS08770	COG2081	HI0933 family
A4203_RS08775	COG3088	subunit of a heme lyase
A4203_RS08775	COG4235	cytochrome complex assembly
A4203_RS08780	COG3088	subunit of a heme lyase
A4203_RS08780	COG4235	cytochrome complex assembly
A4203_RS08790	COG1138	Cytochrome C-type biogenesis protein
A4203_RS08795	COG3301	Polysulphide reductase, NrfD
A4203_RS08800	COG0437	4 iron, 4 sulfur cluster binding
A4203_RS08805	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
A4203_RS08825	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A4203_RS08840	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A4203_RS08875	COG1138	Cytochrome C-type biogenesis protein
A4203_RS08885	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A4203_RS08890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A4203_RS08895	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A4203_RS08905	COG0475	glutathione-regulated potassium exporter activity
A4203_RS08905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A4203_RS08910	COG0431	NADPH-dependent FMN reductase
A4203_RS08920	COG0366	Alpha amylase catalytic
A4203_RS08930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A4203_RS08930	COG1263	PTS System
A4203_RS08940	COG2814	Major facilitator Superfamily
A4203_RS08950	COG0281	malic enzyme
A4203_RS08950	COG0280	phosphate acetyltransferase
A4203_RS08960	COG0737	Belongs to the 5'-nucleotidase family
A4203_RS08970	COG2976	Protein conserved in bacteria
A4203_RS08985	COG1426	Protein conserved in bacteria
A4203_RS08990	COG3063	Type IV pilus biogenesis stability protein PilW
A4203_RS09000	COG0628	permease
A4203_RS09010	COG0521	Mo-molybdopterin cofactor biosynthetic process
A4203_RS09015	COG4589	Belongs to the CDS family
A4203_RS09025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A4203_RS09030	COG0490	domain, Protein
A4203_RS09030	COG0471	metal ion transport
A4203_RS09075	COG0575	Belongs to the CDS family
A4203_RS09115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A4203_RS09120	COG1129	ABC transporter
A4203_RS09120	COG0842	Transport permease protein
A4203_RS09125	COG0842	Transport permease protein
A4203_RS09130	COG1538	Outer membrane efflux protein
A4203_RS09135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A4203_RS09140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A4203_RS09160	COG1652	LysM domain
A4203_RS09165	COG2321	neutral zinc metallopeptidase
A4203_RS09170	COG3730	PTS system glucitol sorbitol-specific
A4203_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
A4203_RS09190	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
A4203_RS09195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A4203_RS09200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A4203_RS09205	COG1349	DNA-binding transcription factor activity
A4203_RS09235	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A4203_RS09240	COG1792	Involved in formation and maintenance of cell shape
A4203_RS09250	COG0557	exoribonuclease II activity
A4203_RS09325	COG1686	Belongs to the peptidase S11 family
A4203_RS09335	COG0772	Belongs to the SEDS family
A4203_RS09340	COG0768	penicillin binding
A4203_RS09350	COG0799	negative regulation of ribosome biogenesis
A4203_RS09360	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A4203_RS09370	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A4203_RS09380	COG1028	Short-chain dehydrogenase reductase Sdr
A4203_RS09385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A4203_RS09405	COG1399	metal-binding, possibly nucleic acid-binding protein
A4203_RS09415	COG0601	transmembrane transport
A4203_RS09420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A4203_RS09430	COG4608	Belongs to the ABC transporter superfamily
A4203_RS09445	COG0500	methyltransferase
A4203_RS09450	COG2830	Protein of unknown function (DUF452)
A4203_RS09460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A4203_RS09470	COG0545	Peptidyl-prolyl cis-trans isomerase
A4203_RS09485	COG2966	Psort location CytoplasmicMembrane, score
A4203_RS09490	COG3610	response to peptide
A4203_RS09495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A4203_RS09500	COG2217	Heavy metal translocating P-type atpase
A4203_RS09505	COG2608	mercury ion transmembrane transporter activity
A4203_RS09515	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A4203_RS09520	COG2205	protein histidine kinase activity
A4203_RS09530	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A4203_RS09545	COG3083	sulfuric ester hydrolase activity
A4203_RS09550	COG0402	S-adenosylhomocysteine deaminase activity
A4203_RS09555	COG1011	Hydrolase
A4203_RS09585	COG1561	YicC-like family, N-terminal region
A4203_RS09590	COG0354	folic acid binding
A4203_RS09620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A4203_RS09635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A4203_RS09640	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A4203_RS09645	COG3307	-O-antigen
A4203_RS09650	COG0191	fructose-bisphosphate aldolase activity
A4203_RS09660	COG3719	Belongs to the RNase T2 family
A4203_RS09665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A4203_RS09670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A4203_RS09675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A4203_RS09680	COG1556	Lactate utilization protein
A4203_RS09685	COG1139	Iron-sulfur cluster binding protein
A4203_RS09690	COG0247	lactate metabolic process
A4203_RS09695	COG1620	l-lactate permease
A4203_RS09700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A4203_RS09710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A4203_RS09715	COG1621	beta-fructofuranosidase activity
A4203_RS09735	COG0859	PFAM glycosyl transferase family 9
A4203_RS09740	COG0859	PFAM glycosyl transferase family 9
A4203_RS09745	COG0513	Belongs to the DEAD box helicase family
A4203_RS09755	COG3201	nicotinamide mononucleotide transporter
A4203_RS09780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A4203_RS09785	COG0778	Nitroreductase
A4203_RS09830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A4203_RS09840	COG1136	(ABC) transporter
A4203_RS09840	COG0577	efflux transmembrane transporter activity
A4203_RS09880	COG3071	HemY protein
A4203_RS09885	COG2959	enzyme of heme biosynthesis
A4203_RS09905	COG2197	response regulator
A4203_RS09910	COG0729	surface antigen
A4203_RS09915	COG2911	Protein conserved in bacteria
A4203_RS09945	COG3085	chromosome segregation
A4203_RS09950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A4203_RS09955	COG3084	Protein conserved in bacteria
A4203_RS09970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A4203_RS09970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A4203_RS09975	COG1105	Belongs to the carbohydrate kinase PfkB family
A4203_RS09980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A4203_RS09980	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A4203_RS09980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A4203_RS09995	COG3005	denitrification pathway
A4203_RS10005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A4203_RS10015	COG1595	DNA-templated transcription, initiation
A4203_RS10020	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
A4203_RS10025	COG3026	antisigma factor binding
A4203_RS10030	COG3086	response to oxidative stress
A4203_RS10035	COG1763	Mo-molybdopterin cofactor biosynthetic process
A4203_RS10040	COG2814	Major facilitator Superfamily
A4203_RS10120	COG0582	viral genome integration into host DNA
A4203_RS10130	COG1957	nucleoside hydrolase
A4203_RS10135	COG3276	selenocysteine insertion sequence binding
A4203_RS10140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A4203_RS10140	COG2221	Nitrite and sulphite reductase 4Fe-4S
A4203_RS10145	COG3381	protein complex oligomerization
A4203_RS10150	COG3302	dmso reductase anchor subunit
A4203_RS10155	COG0437	4 iron, 4 sulfur cluster binding
A4203_RS10160	COG0243	molybdopterin cofactor binding
A4203_RS10165	COG1285	pathogenesis
A4203_RS10170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A4203_RS10170	COG2190	(PTS) system
A4203_RS10170	COG1263	PTS System
A4203_RS10225	COG2610	gluconate transmembrane transporter activity
A4203_RS10230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A4203_RS10235	COG1073	alpha beta
A4203_RS10245	COG3622	Belongs to the hyi family
A4203_RS10250	COG0235	Class ii aldolase
A4203_RS10255	COG3395	kinase activity
A4203_RS10260	COG2084	Dehydrogenase
A4203_RS10265	COG1349	DNA-binding transcription factor activity
A4203_RS10270	COG2195	Cleaves the N-terminal amino acid of tripeptides
A4203_RS10280	COG1312	Catalyzes the dehydration of D-mannonate
A4203_RS10285	COG2186	Transcriptional regulator
A4203_RS10290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A4203_RS10295	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A4203_RS10305	COG1028	Short-chain dehydrogenase reductase Sdr
A4203_RS10315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A4203_RS10320	COG0800	Aldolase
A4203_RS10330	COG1070	Carbohydrate kinase
A4203_RS10335	COG2115	Belongs to the xylose isomerase family
A4203_RS10345	COG1757	Na H antiporter
A4203_RS10350	COG4213	ABC transporter substrate-binding protein
A4203_RS10355	COG1129	ABC transporter
A4203_RS10360	COG4214	carbohydrate transport
A4203_RS10365	COG1609	Transcriptional regulator
A4203_RS10365	COG2207	Transcriptional regulator
A4203_RS10385	COG1940	carbohydrate kinase activity
A4203_RS10400	COG1172	Belongs to the binding-protein-dependent transport system permease family
A4203_RS10410	COG1741	Belongs to the pirin family
A4203_RS10420	COG1017	nitric oxide dioxygenase activity
A4203_RS10420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A4203_RS10425	COG4191	Histidine kinase
A4203_RS10425	COG0784	Response regulator, receiver
A4203_RS10440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A4203_RS10445	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A4203_RS10455	COG2960	long-chain fatty acid transporting porin activity
A4203_RS10460	COG3172	ATPase kinase involved in NAD metabolism
A4203_RS10465	COG2129	metallophosphoesterase
A4203_RS10500	COG0201	protein transport
A4203_RS10575	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A4203_RS10580	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A4203_RS10605	COG0051	transcription antitermination factor activity, RNA binding
A4203_RS10610	COG0038	chloride channel
A4203_RS10620	COG0814	amino acid
A4203_RS10640	COG5016	pyruvate
A4203_RS10640	COG0511	ligase activity, forming carbon-carbon bonds
A4203_RS10650	COG0019	diaminopimelate decarboxylase activity
A4203_RS10660	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
A4203_RS10675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A4203_RS10680	COG1045	serine acetyltransferase
A4203_RS10695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A4203_RS10700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A4203_RS10705	COG0433	COG0433 Predicted ATPase
A4203_RS10720	COG0705	Rhomboid family
A4203_RS10725	COG1349	DNA-binding transcription factor activity
A4203_RS10730	COG0247	lactate metabolic process
A4203_RS10740	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A4203_RS10745	COG2271	Major facilitator Superfamily
A4203_RS10750	COG0584	glycerophosphoryl diester phosphodiesterase
A4203_RS10755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A4203_RS10770	COG2183	response to ionizing radiation
A4203_RS10790	COG1584	GPR1 FUN34 yaaH family protein
A4203_RS10795	COG1454	alcohol dehydrogenase
A4203_RS10795	COG1012	belongs to the aldehyde dehydrogenase family
A4203_RS10805	COG3842	ATPase activity
A4203_RS10810	COG1178	ABC-type Fe3 transport system permease component
A4203_RS10815	COG3842	ATPase activity
A4203_RS10845	COG0512	Glutamine amidotransferase of anthranilate synthase
A4203_RS10855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A4203_RS10880	COG1881	PFAM PEBP family protein
A4203_RS10885	COG1733	regulation of RNA biosynthetic process
A4203_RS10900	COG4988	ABC transporter
A4203_RS10905	COG0697	spore germination
A4203_RS10910	COG0187	DNA topoisomerase II activity
A4203_RS10930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A4203_RS10935	COG0640	Transcriptional regulator