locus-tag	class	description
PMCN01_RS00010	COG0592	DNA-directed DNA polymerase activity
PMCN01_RS00020	COG2226	methyltransferase
PMCN01_RS00045	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PMCN01_RS00075	COG3306	glycosyltransferase involved in LPS biosynthesis
PMCN01_RS00090	COG1216	Glycosyl transferase, family 2
PMCN01_RS00095	COG1442	glycosyl transferase family 8
PMCN01_RS00100	COG0438	transferase activity, transferring glycosyl groups
PMCN01_RS00105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PMCN01_RS00110	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PMCN01_RS00115	COG1309	transcriptional regulator
PMCN01_RS00120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMCN01_RS00125	COG1956	GAF domain-containing protein
PMCN01_RS00130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PMCN01_RS00140	COG1393	Belongs to the ArsC family
PMCN01_RS00145	COG3036	rescue of stalled ribosome
PMCN01_RS00285	COG3617	BRO family, N-terminal domain
PMCN01_RS00515	COG0675	Transposase, IS605 OrfB family
PMCN01_RS00530	COG4785	May be involved in cell division
PMCN01_RS00535	COG0513	Belongs to the DEAD box helicase family
PMCN01_RS00545	COG3842	ATPase activity
PMCN01_RS00550	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PMCN01_RS00575	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
PMCN01_RS00580	COG1027	Aspartate ammonia-lyase
PMCN01_RS00600	COG4545	Glutaredoxin-related protein
PMCN01_RS00630	COG0511	ligase activity, forming carbon-carbon bonds
PMCN01_RS00635	COG0439	Biotin carboxylase
PMCN01_RS00640	COG3924	membrane
PMCN01_RS00645	COG4145	pantothenate transmembrane transporter activity
PMCN01_RS00690	COG0675	Transposase, IS605 OrfB family
PMCN01_RS00710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PMCN01_RS00715	COG4558	Periplasmic binding protein
PMCN01_RS00730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PMCN01_RS00750	COG3691	Protein conserved in bacteria
PMCN01_RS00760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PMCN01_RS00770	COG0861	Integral membrane protein TerC family
PMCN01_RS00780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PMCN01_RS00780	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PMCN01_RS00785	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
PMCN01_RS00790	COG3722	fumarate hydratase activity
PMCN01_RS00805	COG5645	(Lipo)protein
PMCN01_RS00810	COG0210	DNA helicase
PMCN01_RS00835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PMCN01_RS00845	COG1238	metal cluster binding
PMCN01_RS00860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PMCN01_RS00875	COG0697	spore germination
PMCN01_RS00885	COG0561	phosphatase activity
PMCN01_RS00890	COG1702	phosphate starvation-inducible protein PhoH
PMCN01_RS00905	COG1444	tRNA N-acetyltransferase activity
PMCN01_RS00915	COG2194	sulfuric ester hydrolase activity
PMCN01_RS00920	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PMCN01_RS00925	COG4211	Belongs to the binding-protein-dependent transport system permease family
PMCN01_RS00935	COG1879	ABC-type sugar transport system periplasmic component
PMCN01_RS00940	COG1609	Transcriptional regulator
PMCN01_RS00945	COG1085	galactose-1-phosphate uridylyltransferase
PMCN01_RS00955	COG2017	converts alpha-aldose to the beta-anomer
PMCN01_RS00975	COG1088	dTDP-glucose 4,6-dehydratase activity
PMCN01_RS01000	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PMCN01_RS01010	COG1393	Belongs to the ArsC family
PMCN01_RS01020	COG1876	peptidase activity
PMCN01_RS01025	COG0494	nUDIX hydrolase
PMCN01_RS01030	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PMCN01_RS01040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PMCN01_RS01045	COG1596	polysaccharide export
PMCN01_RS01055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PMCN01_RS01070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PMCN01_RS01110	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PMCN01_RS01115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PMCN01_RS01140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMCN01_RS01165	COG0626	cystathionine gamma-synthase activity
PMCN01_RS01185	COG1530	ribonuclease E activity
PMCN01_RS01200	COG2056	Na+-H+ antiporter family
PMCN01_RS01210	COG0346	lactoylglutathione lyase activity
PMCN01_RS01225	COG1755	Isoprenylcysteine carboxyl methyltransferase
PMCN01_RS01240	COG0494	nUDIX hydrolase
PMCN01_RS01275	COG1271	oxidase subunit
PMCN01_RS01280	COG1294	oxidase, subunit
PMCN01_RS01290	COG0824	Thioesterase
PMCN01_RS01295	COG0811	peptide transport
PMCN01_RS01300	COG0848	biopolymer transport protein
PMCN01_RS01305	COG3064	Membrane
PMCN01_RS01330	COG2165	general secretion pathway protein
PMCN01_RS01335	COG4795	General secretion pathway protein
PMCN01_RS01350	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PMCN01_RS01355	COG0456	acetyltransferase
PMCN01_RS01360	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
PMCN01_RS01380	COG1840	ABC-type Fe3 transport system, periplasmic component
PMCN01_RS01385	COG1840	ABC-type Fe3 transport system, periplasmic component
PMCN01_RS01390	COG1840	ABC-type Fe3 transport system, periplasmic component
PMCN01_RS01395	COG1840	ABC-type Fe3 transport system, periplasmic component
PMCN01_RS01400	COG1840	ABC-type Fe3 transport system, periplasmic component
PMCN01_RS01430	COG0659	secondary active sulfate transmembrane transporter activity
PMCN01_RS01435	COG0800	Aldolase
PMCN01_RS01450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PMCN01_RS01455	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PMCN01_RS01460	COG0084	hydrolase, TatD family'
PMCN01_RS01475	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PMCN01_RS01475	COG1328	CTP reductase activity
PMCN01_RS01480	COG1858	cytochrome C peroxidase
PMCN01_RS01490	COG0527	aspartate kinase activity
PMCN01_RS01500	COG2860	membrane
PMCN01_RS01510	COG3069	C4-dicarboxylate transmembrane transporter activity
PMCN01_RS01530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PMCN01_RS01540	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PMCN01_RS01545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PMCN01_RS01550	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PMCN01_RS01555	COG1022	Amp-dependent synthetase and ligase
PMCN01_RS01565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PMCN01_RS01585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PMCN01_RS01645	COG0748	coenzyme F420 binding
PMCN01_RS01650	COG1629	transport
PMCN01_RS01650	COG4771	TonB-dependent receptor
PMCN01_RS01660	COG0489	protein tyrosine kinase activity
PMCN01_RS01695	COG1518	maintenance of DNA repeat elements
PMCN01_RS01705	COG2198	Histidine kinase
PMCN01_RS01705	COG5002	protein histidine kinase activity
PMCN01_RS01705	COG0784	Response regulator, receiver
PMCN01_RS01720	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
PMCN01_RS01725	COG1959	2 iron, 2 sulfur cluster binding
PMCN01_RS01735	COG0822	iron-sulfur transferase activity
PMCN01_RS01740	COG0316	Belongs to the HesB IscA family
PMCN01_RS01755	COG0633	Ferredoxin
PMCN01_RS01770	COG0741	lytic transglycosylase activity
PMCN01_RS01775	COG2350	Protein conserved in bacteria
PMCN01_RS01780	COG1607	acyl-coa hydrolase
PMCN01_RS01800	COG0497	DNA recombination
PMCN01_RS01815	COG1823	symporter activity
PMCN01_RS01830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PMCN01_RS01840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PMCN01_RS01845	COG1530	ribonuclease E activity
PMCN01_RS01860	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PMCN01_RS01865	COG0142	geranyltranstransferase activity
PMCN01_RS01880	COG0697	spore germination
PMCN01_RS01885	COG0697	spore germination
PMCN01_RS01895	COG0735	belongs to the Fur family
PMCN01_RS01900	COG0716	FMN binding
PMCN01_RS01910	COG0596	Alpha beta hydrolase
PMCN01_RS01915	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
PMCN01_RS01920	COG0318	PFAM AMP-dependent synthetase and ligase
PMCN01_RS01925	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PMCN01_RS01925	COG3264	Mechanosensitive ion channel
PMCN01_RS01935	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
PMCN01_RS01940	COG0730	response to heat
PMCN01_RS01945	COG1560	Kdo2-lipid A biosynthetic process
PMCN01_RS01955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PMCN01_RS01965	COG0251	oxidation-reduction process
PMCN01_RS01980	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PMCN01_RS01985	COG0187	DNA topoisomerase II activity
PMCN01_RS01990	COG0019	diaminopimelate decarboxylase activity
PMCN01_RS02005	COG4797	methyltransferase
PMCN01_RS02005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PMCN01_RS02015	COG4143	(ABC) transporter
PMCN01_RS02020	COG1178	ABC-type Fe3 transport system permease component
PMCN01_RS02035	COG0733	neurotransmitter:sodium symporter activity
PMCN01_RS02040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PMCN01_RS02095	COG1289	transmembrane transporter activity
PMCN01_RS02100	COG3304	Inner membrane component domain
PMCN01_RS02120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PMCN01_RS02125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PMCN01_RS02130	COG1121	(ABC) transporter
PMCN01_RS02140	COG2920	part of a sulfur-relay system
PMCN01_RS02160	COG2864	formate dehydrogenase
PMCN01_RS02165	COG0437	4 iron, 4 sulfur cluster binding
PMCN01_RS02170	COG3383	formate dehydrogenase (NAD+) activity
PMCN01_RS02170	COG0243	molybdopterin cofactor binding
PMCN01_RS02175	COG3383	formate dehydrogenase (NAD+) activity
PMCN01_RS02175	COG0243	molybdopterin cofactor binding
PMCN01_RS02185	COG0210	DNA helicase
PMCN01_RS02200	COG0463	Glycosyl transferase, family 2
PMCN01_RS02235	COG0583	DNA-binding transcription factor activity
PMCN01_RS02245	COG0488	(ABC) transporter
PMCN01_RS02250	COG3683	transport system, periplasmic component
PMCN01_RS02255	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
PMCN01_RS02280	COG5002	protein histidine kinase activity
PMCN01_RS02285	COG0745	RESPONSE REGULATOR receiver
PMCN01_RS02315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PMCN01_RS02320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PMCN01_RS02330	COG2062	phosphohistidine phosphatase, SixA
PMCN01_RS02360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PMCN01_RS02365	COG4181	ATPase activity
PMCN01_RS02375	COG1136	(ABC) transporter
PMCN01_RS02375	COG0577	efflux transmembrane transporter activity
PMCN01_RS02390	COG0672	)-iron permease
PMCN01_RS02400	COG2837	iron assimilation
PMCN01_RS02405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PMCN01_RS02420	COG0024	Methionine aminopeptidase
PMCN01_RS02490	COG2431	L-lysine efflux transmembrane transporter activity
PMCN01_RS02495	COG3593	DNA synthesis involved in DNA repair
PMCN01_RS02510	COG3101	peptidyl-lysine hydroxylation
PMCN01_RS02515	COG1131	(ABC) transporter
PMCN01_RS02520	COG0842	Transport permease protein
PMCN01_RS02525	COG2358	TRAP transporter, solute receptor (TAXI family
PMCN01_RS02540	COG1611	Belongs to the LOG family
PMCN01_RS02550	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
PMCN01_RS02555	COG3098	single-species biofilm formation
PMCN01_RS02575	COG1067	ATP-dependent peptidase activity
PMCN01_RS02585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PMCN01_RS02590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PMCN01_RS02665	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PMCN01_RS02680	COG3306	glycosyltransferase involved in LPS biosynthesis
PMCN01_RS02690	COG1216	Glycosyl transferase, family 2
PMCN01_RS02695	COG1216	Glycosyl transferase, family 2
PMCN01_RS02700	COG2951	lytic endotransglycosylase activity
PMCN01_RS02705	COG2252	PERMEase
PMCN01_RS02710	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PMCN01_RS02715	COG1074	ATP-dependent DNA helicase activity
PMCN01_RS02720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PMCN01_RS02725	COG2999	glutathione oxidoreductase activity
PMCN01_RS02750	COG2969	positive regulation of protein catabolic process
PMCN01_RS02755	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PMCN01_RS02760	COG0517	IMP dehydrogenase activity
PMCN01_RS02760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PMCN01_RS02775	COG1538	Outer membrane efflux protein
PMCN01_RS02785	COG1115	amino acid carrier protein
PMCN01_RS02805	COG0142	geranyltranstransferase activity
PMCN01_RS02815	COG0243	molybdopterin cofactor binding
PMCN01_RS02820	COG3005	denitrification pathway
PMCN01_RS02850	COG1640	4-alpha-glucanotransferase
PMCN01_RS02860	COG1523	belongs to the glycosyl hydrolase 13 family
PMCN01_RS02890	COG1090	epimerase
PMCN01_RS02910	COG3102	Protein conserved in bacteria
PMCN01_RS02920	COG3133	Outer membrane lipoprotein
PMCN01_RS02945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMCN01_RS02950	COG4591	ABC-type transport system involved in lipoprotein release permease component
PMCN01_RS02960	COG4591	ABC-type transport system involved in lipoprotein release permease component
PMCN01_RS02965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PMCN01_RS02975	COG0402	S-adenosylhomocysteine deaminase activity
PMCN01_RS02980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PMCN01_RS02985	COG0583	DNA-binding transcription factor activity
PMCN01_RS02995	COG2833	Protein of unknown function (DUF455)
PMCN01_RS03000	COG1946	Acyl-CoA thioesterase
PMCN01_RS03010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PMCN01_RS03015	COG4988	ABC transporter
PMCN01_RS03020	COG0492	ferredoxin-NADP+ reductase activity
PMCN01_RS03025	COG3118	belongs to the thioredoxin family
PMCN01_RS03030	COG0288	reversible hydration of carbon dioxide
PMCN01_RS03035	COG1629	transport
PMCN01_RS03050	COG4221	oxidoreductase activity
PMCN01_RS03070	COG0512	Glutamine amidotransferase of anthranilate synthase
PMCN01_RS03075	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PMCN01_RS03080	COG0616	signal peptide processing
PMCN01_RS03095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PMCN01_RS03115	COG0747	negative chemotaxis
PMCN01_RS03125	COG0730	response to heat
PMCN01_RS03130	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PMCN01_RS03135	COG3119	arylsulfatase activity
PMCN01_RS03140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PMCN01_RS03145	COG0641	radical SAM
PMCN01_RS03150	COG0676	glucose-6-phosphate 1-epimerase activity
PMCN01_RS03160	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PMCN01_RS03200	COG0697	spore germination
PMCN01_RS03205	COG2925	Exonuclease
PMCN01_RS03210	COG4575	ribosome binding
PMCN01_RS03230	COG0613	PHP domain protein
PMCN01_RS03240	COG0308	aminopeptidase N
PMCN01_RS03245	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PMCN01_RS03250	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PMCN01_RS03255	COG1448	Aminotransferase
PMCN01_RS03265	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PMCN01_RS03285	COG0791	NLP P60 protein
PMCN01_RS03315	COG0564	pseudouridine synthase activity
PMCN01_RS03320	COG0406	alpha-ribazole phosphatase activity
PMCN01_RS03325	COG0285	dihydrofolate synthase activity
PMCN01_RS03350	COG0586	Pfam SNARE associated Golgi protein
PMCN01_RS03360	COG1940	carbohydrate kinase activity
PMCN01_RS03370	COG4953	penicillin-binding protein 1C
PMCN01_RS03390	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PMCN01_RS03395	COG2823	Periplasmic or secreted lipoprotein
PMCN01_RS03400	COG0307	riboflavin synthase, alpha
PMCN01_RS03410	COG0673	inositol 2-dehydrogenase activity
PMCN01_RS03415	COG0469	pyruvate kinase activity
PMCN01_RS03450	COG0583	DNA-binding transcription factor activity
PMCN01_RS03460	COG0009	L-threonylcarbamoyladenylate synthase
PMCN01_RS03465	COG4409	exo-alpha-(2->6)-sialidase activity
PMCN01_RS03470	COG0287	Prephenate dehydrogenase
PMCN01_RS03470	COG1605	Chorismate mutase
PMCN01_RS03475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PMCN01_RS03480	COG1528	Iron-storage protein
PMCN01_RS03485	COG1528	Iron-storage protein
PMCN01_RS03495	COG0589	response to stress
PMCN01_RS03505	COG0616	signal peptide processing
PMCN01_RS03510	COG0778	Nitroreductase
PMCN01_RS03515	COG0515	serine threonine protein kinase
PMCN01_RS03530	COG0671	phosphoesterase, PA-phosphatase related
PMCN01_RS03540	COG4166	transmembrane transport
PMCN01_RS03545	COG2832	Protein of unknown function (DUF454)
PMCN01_RS03550	COG0339	signal peptide processing
PMCN01_RS03580	COG1846	Transcriptional regulator
PMCN01_RS03580	COG1940	carbohydrate kinase activity
PMCN01_RS03595	COG2226	methyltransferase
PMCN01_RS03600	COG1944	ATP diphosphatase activity
PMCN01_RS03605	COG3105	Protein conserved in bacteria
PMCN01_RS03615	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
PMCN01_RS03620	COG0708	Exodeoxyribonuclease III
PMCN01_RS03635	COG0303	'Molybdopterin
PMCN01_RS03640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PMCN01_RS03645	COG0163	prenyltransferase activity
PMCN01_RS03655	COG1286	toxin biosynthetic process
PMCN01_RS03670	COG0280	phosphate acetyltransferase
PMCN01_RS03670	COG0857	belongs to the CobB CobQ family
PMCN01_RS03675	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PMCN01_RS03680	COG0318	PFAM AMP-dependent synthetase and ligase
PMCN01_RS03685	COG3065	identical protein binding
PMCN01_RS03690	COG1214	PFAM Peptidase M22, glycoprotease
PMCN01_RS03695	COG1199	ATP-dependent helicase activity
PMCN01_RS03700	COG0676	glucose-6-phosphate 1-epimerase activity
PMCN01_RS03710	COG1534	Rna-binding protein
PMCN01_RS03725	COG2027	D-alanyl-D-alanine carboxypeptidase
PMCN01_RS03730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PMCN01_RS03735	COG0733	neurotransmitter:sodium symporter activity
PMCN01_RS03740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PMCN01_RS03760	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PMCN01_RS03795	COG1280	lysine exporter protein (LysE YggA)
PMCN01_RS03800	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PMCN01_RS03805	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PMCN01_RS03820	COG0814	amino acid
PMCN01_RS03825	COG0778	Nitroreductase
PMCN01_RS03830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PMCN01_RS03835	COG5339	Protein conserved in bacteria
PMCN01_RS03865	COG4771	TonB-dependent receptor
PMCN01_RS03865	COG1629	transport
PMCN01_RS03875	COG4149	molybdate abc transporter
PMCN01_RS03880	COG0725	ABC transporter, periplasmic molybdate-binding protein
PMCN01_RS03890	COG2005	Transcriptional regulator
PMCN01_RS03900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PMCN01_RS03905	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PMCN01_RS03905	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PMCN01_RS03920	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PMCN01_RS03925	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PMCN01_RS03970	COG0195	Participates in both transcription termination and antitermination
PMCN01_RS04005	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
PMCN01_RS04025	COG1643	Atp-dependent helicase
PMCN01_RS04030	COG2363	Small membrane protein
PMCN01_RS04065	COG0463	Glycosyl transferase, family 2
PMCN01_RS04095	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PMCN01_RS04105	COG1704	LemA family
PMCN01_RS04110	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PMCN01_RS04110	COG2885	chlorophyll binding
PMCN01_RS04115	COG0247	lactate metabolic process
PMCN01_RS04115	COG0277	FAD linked oxidase domain protein
PMCN01_RS04135	COG3265	gluconokinase activity
PMCN01_RS04140	COG1609	Transcriptional regulator
PMCN01_RS04145	COG1063	alcohol dehydrogenase
PMCN01_RS04150	COG1028	Short-chain dehydrogenase reductase Sdr
PMCN01_RS04155	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PMCN01_RS04165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PMCN01_RS04165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PMCN01_RS04170	COG0626	cystathionine gamma-synthase activity
PMCN01_RS04175	COG0450	alkyl hydroperoxide reductase
PMCN01_RS04180	COG0023	Translation Initiation Factor
PMCN01_RS04190	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PMCN01_RS04195	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
PMCN01_RS04205	COG0539	negative regulation of cytoplasmic translation
PMCN01_RS04215	COG4771	TonB-dependent receptor
PMCN01_RS04220	COG0612	Peptidase, M16
PMCN01_RS04225	COG1982	Orn Lys Arg decarboxylase major
PMCN01_RS04230	COG0531	amino acid
PMCN01_RS04240	COG2990	Protein conserved in bacteria
PMCN01_RS04245	COG0814	amino acid
PMCN01_RS04260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PMCN01_RS04280	COG0783	Belongs to the Dps family
PMCN01_RS04305	COG2927	DNA polymerase III (CHI subunit)
PMCN01_RS04315	COG2268	Band 7 protein
PMCN01_RS04330	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PMCN01_RS04355	COG3716	PTS system mannose fructose sorbose family IID component
PMCN01_RS04360	COG3715	PTS system
PMCN01_RS04365	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PMCN01_RS04365	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
PMCN01_RS04370	COG2814	Major facilitator Superfamily
PMCN01_RS04400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PMCN01_RS04405	COG3094	Invasion gene expression up-regulator, SirB
PMCN01_RS04455	COG1450	Type ii and iii secretion system protein
PMCN01_RS04485	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PMCN01_RS04515	COG2333	competence protein COMEC
PMCN01_RS04515	COG0658	competence protein
PMCN01_RS04525	COG0617	tRNA 3'-terminal CCA addition
PMCN01_RS04530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PMCN01_RS04540	COG2949	membrane
PMCN01_RS04550	COG0440	acetolactate synthase activity
PMCN01_RS04555	COG0028	Belongs to the TPP enzyme family
PMCN01_RS04560	COG1757	Na H antiporter
PMCN01_RS04565	COG2916	Histone family protein nucleoid-structuring protein H-NS
PMCN01_RS04570	COG0788	formyltetrahydrofolate deformylase activity
PMCN01_RS04575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PMCN01_RS04585	COG2190	(PTS) system
PMCN01_RS04585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PMCN01_RS04585	COG1263	PTS System
PMCN01_RS04590	COG0488	(ABC) transporter
PMCN01_RS04600	COG1346	cytolysis
PMCN01_RS04610	COG1525	nuclease
PMCN01_RS04620	COG2166	iron-sulfur cluster assembly
PMCN01_RS04630	COG1560	Kdo2-lipid A biosynthetic process
PMCN01_RS04635	COG3381	protein complex oligomerization
PMCN01_RS04640	COG2249	NAD(P)H dehydrogenase (quinone) activity
PMCN01_RS04650	COG0330	HflC and HflK could
PMCN01_RS04655	COG1119	ATPase activity
PMCN01_RS04665	COG2932	Transcriptional regulator
PMCN01_RS04670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PMCN01_RS04675	COG0508	dehydrogenase complex catalyzes the overall conversion of
PMCN01_RS04680	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PMCN01_RS04685	COG2190	(PTS) system
PMCN01_RS04690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PMCN01_RS04695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PMCN01_RS04720	COG0802	atpase or kinase
PMCN01_RS04725	COG0860	N-Acetylmuramoyl-L-alanine amidase
PMCN01_RS04725	COG1388	LysM domain
PMCN01_RS04745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PMCN01_RS04750	COG3283	Transcriptional regulator of aromatic amino acids metabolism
PMCN01_RS04760	COG3106	COG3106 Predicted ATPase
PMCN01_RS04765	COG4166	transmembrane transport
PMCN01_RS04770	COG4168	peptide transport system, permease
PMCN01_RS04775	COG4171	peptide transport system, permease
PMCN01_RS04780	COG4172	Belongs to the ABC transporter superfamily
PMCN01_RS04785	COG4172	Belongs to the ABC transporter superfamily
PMCN01_RS04820	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PMCN01_RS04820	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PMCN01_RS04870	COG2252	PERMEase
PMCN01_RS04880	COG2814	Major facilitator Superfamily
PMCN01_RS04890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PMCN01_RS04905	COG0508	dehydrogenase complex catalyzes the overall conversion of
PMCN01_RS04910	COG0567	Dehydrogenase, E1 component
PMCN01_RS04935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PMCN01_RS04940	COG3108	Peptidase M15
PMCN01_RS04945	COG2989	Protein conserved in bacteria
PMCN01_RS04950	COG0793	Belongs to the peptidase S41A family
PMCN01_RS04960	COG2995	paraquat-inducible protein a
PMCN01_RS04965	COG3008	intermembrane lipid transfer
PMCN01_RS04980	COG1176	ABC-type spermidine putrescine transport system, permease component I
PMCN01_RS04985	COG1177	transmembrane transport
PMCN01_RS04990	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PMCN01_RS04995	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PMCN01_RS05010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PMCN01_RS05025	COG1522	sequence-specific DNA binding
PMCN01_RS05035	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PMCN01_RS05040	COG3025	triphosphatase activity
PMCN01_RS05045	COG1392	Phosphate transport regulator
PMCN01_RS05050	COG0306	phosphate transporter
PMCN01_RS05055	COG4991	sh3 domain protein
PMCN01_RS05080	COG0739	heme binding
PMCN01_RS05090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PMCN01_RS05095	COG4608	Belongs to the ABC transporter superfamily
PMCN01_RS05100	COG0444	Belongs to the ABC transporter superfamily
PMCN01_RS05105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PMCN01_RS05110	COG0601	transmembrane transport
PMCN01_RS05115	COG0747	negative chemotaxis
PMCN01_RS05120	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PMCN01_RS05130	COG0826	peptidase U32
PMCN01_RS05150	COG0561	phosphatase activity
PMCN01_RS05155	COG3069	C4-dicarboxylate transmembrane transporter activity
PMCN01_RS05165	COG1862	Preprotein translocase
PMCN01_RS05170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PMCN01_RS05175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PMCN01_RS05210	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PMCN01_RS05215	COG0745	RESPONSE REGULATOR receiver
PMCN01_RS05230	COG3585	molybdate ion transport
PMCN01_RS05235	COG0642	Histidine kinase
PMCN01_RS05240	COG0745	RESPONSE REGULATOR receiver
PMCN01_RS05245	COG2259	Doxx family
PMCN01_RS05260	COG3219	Protein conserved in bacteria
PMCN01_RS05270	COG1595	DNA-templated transcription, initiation
PMCN01_RS05305	COG1840	ABC-type Fe3 transport system, periplasmic component
PMCN01_RS05315	COG1053	succinate dehydrogenase
PMCN01_RS05320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PMCN01_RS05335	COG0795	lipopolysaccharide-transporting ATPase activity
PMCN01_RS05340	COG0795	lipopolysaccharide-transporting ATPase activity
PMCN01_RS05355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PMCN01_RS05360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PMCN01_RS05385	COG1083	cytidylyl-transferase
PMCN01_RS05395	COG0720	synthase
PMCN01_RS05400	COG0602	queuosine metabolic process
PMCN01_RS05410	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PMCN01_RS05425	COG5007	Belongs to the BolA IbaG family
PMCN01_RS05430	COG3113	response to antibiotic
PMCN01_RS05435	COG2854	intermembrane phospholipid transfer
PMCN01_RS05440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PMCN01_RS05445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PMCN01_RS05450	COG1127	ABC transporter
PMCN01_RS05455	COG3117	lipopolysaccharide transmembrane transporter activity
PMCN01_RS05460	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PMCN01_RS05465	COG1137	ATPase activity
PMCN01_RS05470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PMCN01_RS05485	COG2850	peptidyl-arginine hydroxylation
PMCN01_RS05495	COG2867	negative regulation of translational initiation
PMCN01_RS05510	COG0531	amino acid
PMCN01_RS05520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PMCN01_RS05525	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
PMCN01_RS05530	COG2824	Alkylphosphonate utilization operon protein PhnA
PMCN01_RS05550	COG1172	Belongs to the binding-protein-dependent transport system permease family
PMCN01_RS05555	COG1879	ABC-type sugar transport system periplasmic component
PMCN01_RS05560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PMCN01_RS05570	COG1605	Chorismate mutase
PMCN01_RS05570	COG0077	Prephenate dehydratase
PMCN01_RS05575	COG1979	alcohol dehydrogenase
PMCN01_RS05585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PMCN01_RS05590	COG0849	cell division
PMCN01_RS05595	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PMCN01_RS05630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PMCN01_RS05640	COG0768	penicillin binding
PMCN01_RS05645	COG3116	cell division
PMCN01_RS05660	COG1966	Carbon starvation protein
PMCN01_RS05665	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
PMCN01_RS05670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PMCN01_RS05675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PMCN01_RS05680	COG1120	ATPase activity
PMCN01_RS05690	COG4160	amino acid transport
PMCN01_RS05695	COG4215	(ABC) transporter
PMCN01_RS05700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMCN01_RS05705	COG1126	abc transporter atp-binding protein
PMCN01_RS05715	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PMCN01_RS05720	COG0312	modulator of DNA gyrase
PMCN01_RS05730	COG0330	HflC and HflK could
PMCN01_RS05735	COG0330	HflC and HflK could
PMCN01_RS05745	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PMCN01_RS05755	COG0460	homoserine dehydrogenase
PMCN01_RS05755	COG0527	aspartate kinase activity
PMCN01_RS05835	COG0204	Acyl-transferase
PMCN01_RS05845	COG5413	integral membrane protein
PMCN01_RS05855	COG1509	lysine 2,3-aminomutase activity
PMCN01_RS05860	COG3061	Opacity-associated protein A
PMCN01_RS05860	COG3266	domain, Protein
PMCN01_RS05880	COG2814	Major facilitator Superfamily
PMCN01_RS05890	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PMCN01_RS05895	COG1115	amino acid carrier protein
PMCN01_RS05920	COG1459	type II secretion system
PMCN01_RS05925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PMCN01_RS05930	COG4969	Belongs to the N-Me-Phe pilin family
PMCN01_RS05935	COG3023	N-Acetylmuramoyl-L-alanine amidase
PMCN01_RS05945	COG0730	response to heat
PMCN01_RS05960	COG0590	tRNA wobble adenosine to inosine editing
PMCN01_RS05965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PMCN01_RS05975	COG1882	Formate acetyltransferase
PMCN01_RS05980	COG2116	formate transmembrane transporter activity
PMCN01_RS05985	COG0537	adenosine 5'-monophosphoramidase activity
PMCN01_RS06010	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PMCN01_RS06040	COG0681	Belongs to the peptidase S26 family
PMCN01_RS06075	COG2267	carboxylic ester hydrolase activity
PMCN01_RS06090	COG0436	Aminotransferase
PMCN01_RS06105	COG3842	ATPase activity
PMCN01_RS06130	COG2095	MarC family integral membrane protein
PMCN01_RS06135	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PMCN01_RS06140	COG0748	coenzyme F420 binding
PMCN01_RS06145	COG4178	(ABC) transporter
PMCN01_RS06160	COG0121	glutamine amidotransferase
PMCN01_RS06165	COG0814	amino acid
PMCN01_RS06170	COG1760	l-serine dehydratase
PMCN01_RS06175	COG3738	Protein conserved in bacteria
PMCN01_RS06185	COG0753	catalase activity
PMCN01_RS06190	COG2081	HI0933 family
PMCN01_RS06195	COG4235	cytochrome complex assembly
PMCN01_RS06195	COG3088	subunit of a heme lyase
PMCN01_RS06200	COG3088	subunit of a heme lyase
PMCN01_RS06200	COG4235	cytochrome complex assembly
PMCN01_RS06210	COG1138	Cytochrome C-type biogenesis protein
PMCN01_RS06215	COG3301	Polysulphide reductase, NrfD
PMCN01_RS06220	COG0437	4 iron, 4 sulfur cluster binding
PMCN01_RS06225	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
PMCN01_RS06245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PMCN01_RS06260	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PMCN01_RS06275	COG0346	lactoylglutathione lyase activity
PMCN01_RS06295	COG1138	Cytochrome C-type biogenesis protein
PMCN01_RS06305	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PMCN01_RS06310	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PMCN01_RS06315	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PMCN01_RS06325	COG0475	glutathione-regulated potassium exporter activity
PMCN01_RS06325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PMCN01_RS06330	COG0431	NADPH-dependent FMN reductase
PMCN01_RS06340	COG0366	Alpha amylase catalytic
PMCN01_RS06350	COG1263	PTS System
PMCN01_RS06350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PMCN01_RS06360	COG2814	Major facilitator Superfamily
PMCN01_RS06370	COG0281	malic enzyme
PMCN01_RS06370	COG0280	phosphate acetyltransferase
PMCN01_RS06380	COG0737	Belongs to the 5'-nucleotidase family
PMCN01_RS06390	COG2976	Protein conserved in bacteria
PMCN01_RS06405	COG1426	Protein conserved in bacteria
PMCN01_RS06410	COG3063	Type IV pilus biogenesis stability protein PilW
PMCN01_RS06420	COG0628	permease
PMCN01_RS06430	COG0521	Mo-molybdopterin cofactor biosynthetic process
PMCN01_RS06435	COG4589	Belongs to the CDS family
PMCN01_RS06445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PMCN01_RS06450	COG0490	domain, Protein
PMCN01_RS06450	COG0471	metal ion transport
PMCN01_RS06495	COG0575	Belongs to the CDS family
PMCN01_RS06535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMCN01_RS06540	COG0842	Transport permease protein
PMCN01_RS06540	COG1129	ABC transporter
PMCN01_RS06545	COG0842	Transport permease protein
PMCN01_RS06550	COG1538	Outer membrane efflux protein
PMCN01_RS06555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PMCN01_RS06560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PMCN01_RS06580	COG1652	LysM domain
PMCN01_RS06585	COG2321	neutral zinc metallopeptidase
PMCN01_RS06590	COG3730	PTS system glucitol sorbitol-specific
PMCN01_RS06605	COG1028	Short-chain dehydrogenase reductase Sdr
PMCN01_RS06610	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
PMCN01_RS06615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PMCN01_RS06620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PMCN01_RS06625	COG1349	DNA-binding transcription factor activity
PMCN01_RS06655	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PMCN01_RS06660	COG1792	Involved in formation and maintenance of cell shape
PMCN01_RS06670	COG0557	exoribonuclease II activity
PMCN01_RS06715	COG0582	viral genome integration into host DNA
PMCN01_RS06800	COG3617	BRO family, N-terminal domain
PMCN01_RS06900	COG3179	chitinase
PMCN01_RS06960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PMCN01_RS07055	COG0675	Transposase, IS605 OrfB family
PMCN01_RS07090	COG1686	Belongs to the peptidase S11 family
PMCN01_RS07100	COG0772	Belongs to the SEDS family
PMCN01_RS07105	COG0768	penicillin binding
PMCN01_RS07115	COG0799	negative regulation of ribosome biogenesis
PMCN01_RS07125	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PMCN01_RS07135	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PMCN01_RS07145	COG1028	Short-chain dehydrogenase reductase Sdr
PMCN01_RS07150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PMCN01_RS07170	COG1399	metal-binding, possibly nucleic acid-binding protein
PMCN01_RS07180	COG0601	transmembrane transport
PMCN01_RS07185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PMCN01_RS07195	COG4608	Belongs to the ABC transporter superfamily
PMCN01_RS07210	COG0500	methyltransferase
PMCN01_RS07215	COG2830	Protein of unknown function (DUF452)
PMCN01_RS07225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PMCN01_RS07235	COG0545	Peptidyl-prolyl cis-trans isomerase
PMCN01_RS07250	COG2966	Psort location CytoplasmicMembrane, score
PMCN01_RS07255	COG3610	response to peptide
PMCN01_RS07260	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PMCN01_RS07265	COG2217	Heavy metal translocating P-type atpase
PMCN01_RS07270	COG2608	mercury ion transmembrane transporter activity
PMCN01_RS07280	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PMCN01_RS07285	COG2205	protein histidine kinase activity
PMCN01_RS07290	COG0745	RESPONSE REGULATOR receiver
PMCN01_RS07295	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PMCN01_RS07310	COG3083	sulfuric ester hydrolase activity
PMCN01_RS07315	COG0402	S-adenosylhomocysteine deaminase activity
PMCN01_RS07320	COG1011	Hydrolase
PMCN01_RS07350	COG1561	YicC-like family, N-terminal region
PMCN01_RS07355	COG0354	folic acid binding
PMCN01_RS07385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PMCN01_RS07400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PMCN01_RS07405	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PMCN01_RS07410	COG3307	-O-antigen
PMCN01_RS07420	COG0191	fructose-bisphosphate aldolase activity
PMCN01_RS07430	COG3719	Belongs to the RNase T2 family
PMCN01_RS07435	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PMCN01_RS07440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PMCN01_RS07445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PMCN01_RS07450	COG1556	Lactate utilization protein
PMCN01_RS07455	COG1139	Iron-sulfur cluster binding protein
PMCN01_RS07460	COG0247	lactate metabolic process
PMCN01_RS07465	COG1620	l-lactate permease
PMCN01_RS07470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PMCN01_RS07480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PMCN01_RS07485	COG1621	beta-fructofuranosidase activity
PMCN01_RS07505	COG0859	PFAM glycosyl transferase family 9
PMCN01_RS07510	COG0859	PFAM glycosyl transferase family 9
PMCN01_RS07515	COG0513	Belongs to the DEAD box helicase family
PMCN01_RS07525	COG3201	nicotinamide mononucleotide transporter
PMCN01_RS07550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PMCN01_RS07555	COG0778	Nitroreductase
PMCN01_RS07600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PMCN01_RS07610	COG1136	(ABC) transporter
PMCN01_RS07610	COG0577	efflux transmembrane transporter activity
PMCN01_RS07650	COG3071	HemY protein
PMCN01_RS07655	COG2959	enzyme of heme biosynthesis
PMCN01_RS07675	COG2197	response regulator
PMCN01_RS07680	COG0729	surface antigen
PMCN01_RS07685	COG2911	Protein conserved in bacteria
PMCN01_RS07690	COG0248	Ppx GppA phosphatase
PMCN01_RS07715	COG3085	chromosome segregation
PMCN01_RS07720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PMCN01_RS07725	COG3084	Protein conserved in bacteria
PMCN01_RS07740	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PMCN01_RS07740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PMCN01_RS07745	COG1105	Belongs to the carbohydrate kinase PfkB family
PMCN01_RS07750	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PMCN01_RS07750	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PMCN01_RS07750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PMCN01_RS07765	COG3005	denitrification pathway
PMCN01_RS07775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PMCN01_RS07785	COG1595	DNA-templated transcription, initiation
PMCN01_RS07790	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
PMCN01_RS07795	COG3026	antisigma factor binding
PMCN01_RS07800	COG3086	response to oxidative stress
PMCN01_RS07805	COG1763	Mo-molybdopterin cofactor biosynthetic process
PMCN01_RS07810	COG2814	Major facilitator Superfamily
PMCN01_RS07830	COG1957	nucleoside hydrolase
PMCN01_RS07835	COG3276	selenocysteine insertion sequence binding
PMCN01_RS07840	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PMCN01_RS07840	COG2221	Nitrite and sulphite reductase 4Fe-4S
PMCN01_RS07845	COG3381	protein complex oligomerization
PMCN01_RS07850	COG3302	dmso reductase anchor subunit
PMCN01_RS07855	COG0437	4 iron, 4 sulfur cluster binding
PMCN01_RS07860	COG0243	molybdopterin cofactor binding
PMCN01_RS07865	COG1285	pathogenesis
PMCN01_RS07870	COG2190	(PTS) system
PMCN01_RS07870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PMCN01_RS07870	COG1263	PTS System
PMCN01_RS07925	COG2610	gluconate transmembrane transporter activity
PMCN01_RS07930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PMCN01_RS07935	COG1073	alpha beta
PMCN01_RS07945	COG3622	Belongs to the hyi family
PMCN01_RS07950	COG0235	Class ii aldolase
PMCN01_RS07955	COG3395	kinase activity
PMCN01_RS07960	COG2084	Dehydrogenase
PMCN01_RS07965	COG1349	DNA-binding transcription factor activity
PMCN01_RS07970	COG2195	Cleaves the N-terminal amino acid of tripeptides
PMCN01_RS07980	COG1312	Catalyzes the dehydration of D-mannonate
PMCN01_RS07985	COG2186	Transcriptional regulator
PMCN01_RS07990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PMCN01_RS07995	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PMCN01_RS08005	COG1028	Short-chain dehydrogenase reductase Sdr
PMCN01_RS08015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PMCN01_RS08020	COG0800	Aldolase
PMCN01_RS08030	COG1070	Carbohydrate kinase
PMCN01_RS08035	COG2115	Belongs to the xylose isomerase family
PMCN01_RS08045	COG1757	Na H antiporter
PMCN01_RS08050	COG4213	ABC transporter substrate-binding protein
PMCN01_RS08055	COG1129	ABC transporter
PMCN01_RS08060	COG4214	carbohydrate transport
PMCN01_RS08065	COG2207	Transcriptional regulator
PMCN01_RS08065	COG1609	Transcriptional regulator
PMCN01_RS08085	COG1940	carbohydrate kinase activity
PMCN01_RS08100	COG1172	Belongs to the binding-protein-dependent transport system permease family
PMCN01_RS08110	COG1741	Belongs to the pirin family
PMCN01_RS08120	COG1017	nitric oxide dioxygenase activity
PMCN01_RS08120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PMCN01_RS08125	COG0784	Response regulator, receiver
PMCN01_RS08125	COG4191	Histidine kinase
PMCN01_RS08140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMCN01_RS08145	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PMCN01_RS08155	COG2960	long-chain fatty acid transporting porin activity
PMCN01_RS08160	COG3172	ATPase kinase involved in NAD metabolism
PMCN01_RS08165	COG2129	metallophosphoesterase
PMCN01_RS08200	COG0201	protein transport
PMCN01_RS08275	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PMCN01_RS08280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PMCN01_RS08305	COG0051	transcription antitermination factor activity, RNA binding
PMCN01_RS08310	COG0038	chloride channel
PMCN01_RS08320	COG0814	amino acid
PMCN01_RS08335	COG0511	ligase activity, forming carbon-carbon bonds
PMCN01_RS08335	COG5016	pyruvate
PMCN01_RS08345	COG0019	diaminopimelate decarboxylase activity
PMCN01_RS08355	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
PMCN01_RS08370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PMCN01_RS08375	COG1045	serine acetyltransferase
PMCN01_RS08390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PMCN01_RS08395	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PMCN01_RS08400	COG0433	COG0433 Predicted ATPase
PMCN01_RS08415	COG0705	Rhomboid family
PMCN01_RS08420	COG1349	DNA-binding transcription factor activity
PMCN01_RS08425	COG0247	lactate metabolic process
PMCN01_RS08435	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PMCN01_RS08440	COG2271	Major facilitator Superfamily
PMCN01_RS08445	COG0584	glycerophosphoryl diester phosphodiesterase
PMCN01_RS08450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PMCN01_RS08465	COG2183	response to ionizing radiation
PMCN01_RS08485	COG1584	GPR1 FUN34 yaaH family protein
PMCN01_RS08490	COG1454	alcohol dehydrogenase
PMCN01_RS08490	COG1012	belongs to the aldehyde dehydrogenase family
PMCN01_RS08500	COG3842	ATPase activity
PMCN01_RS08505	COG1178	ABC-type Fe3 transport system permease component
PMCN01_RS08510	COG3842	ATPase activity
PMCN01_RS08540	COG0512	Glutamine amidotransferase of anthranilate synthase
PMCN01_RS08550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PMCN01_RS08575	COG1881	PFAM PEBP family protein
PMCN01_RS08580	COG1733	regulation of RNA biosynthetic process
PMCN01_RS08590	COG1132	(ABC) transporter
PMCN01_RS08595	COG4988	ABC transporter
PMCN01_RS08600	COG0697	spore germination
PMCN01_RS08605	COG0187	DNA topoisomerase II activity
PMCN01_RS08625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PMCN01_RS08630	COG0640	Transcriptional regulator
PMCN01_RS08635	COG1494	fructose-1,6-bisphosphatase
PMCN01_RS08710	COG1739	Uncharacterized protein family UPF0029
PMCN01_RS08715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PMCN01_RS08760	COG2853	Lipoprotein
PMCN01_RS08795	COG4942	peptidase
PMCN01_RS08800	COG2861	carbohydrate metabolic process
PMCN01_RS08810	COG4206	TonB-dependent receptor
PMCN01_RS08810	COG1629	transport
PMCN01_RS08815	COG1629	transport
PMCN01_RS08815	COG4206	TonB-dependent receptor
PMCN01_RS08820	COG0606	chelatase, subunit chli
PMCN01_RS08830	COG2990	Protein conserved in bacteria
PMCN01_RS08835	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PMCN01_RS08850	COG0742	ribosomal rna small subunit methyltransferase
PMCN01_RS08865	COG0552	protein localization to endoplasmic reticulum
PMCN01_RS08870	COG2884	Cell division ATP-binding protein ftsE
PMCN01_RS08875	COG2177	Part of the ABC transporter FtsEX involved in
PMCN01_RS08920	COG1012	belongs to the aldehyde dehydrogenase family
PMCN01_RS08925	COG3384	dioxygenase
PMCN01_RS08935	COG2814	Major facilitator Superfamily
PMCN01_RS08940	COG3971	2-oxopent-4-enoate hydratase activity
PMCN01_RS08965	COG0494	nUDIX hydrolase
PMCN01_RS08970	COG1011	Hydrolase
PMCN01_RS08975	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PMCN01_RS08985	COG1218	3'(2'),5'-bisphosphate nucleotidase
PMCN01_RS08990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PMCN01_RS08995	COG0363	glucosamine-6-phosphate deaminase activity
PMCN01_RS09000	COG0625	glutathione transferase activity
PMCN01_RS09025	COG1040	competence protein
PMCN01_RS09035	COG3070	regulator of competence-specific genes
PMCN01_RS09075	COG1215	transferase activity, transferring glycosyl groups
PMCN01_RS09080	COG0569	domain protein
PMCN01_RS09090	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
PMCN01_RS09110	COG2841	Protein conserved in bacteria
PMCN01_RS09115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PMCN01_RS09130	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
PMCN01_RS09135	COG1522	sequence-specific DNA binding
PMCN01_RS09170	COG2358	TRAP transporter, solute receptor (TAXI family
PMCN01_RS09185	COG2095	MarC family integral membrane protein
PMCN01_RS09190	COG0488	(ABC) transporter
PMCN01_RS09200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PMCN01_RS09205	COG0471	metal ion transport
PMCN01_RS09210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PMCN01_RS09215	COG1275	C4-dicarboxylate transporter malic acid transport protein
PMCN01_RS09235	COG3850	Histidine kinase
PMCN01_RS09240	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PMCN01_RS09245	COG3062	negative regulation of establishment of protein localization
PMCN01_RS09255	COG0437	4 iron, 4 sulfur cluster binding
PMCN01_RS09260	COG0348	domain, Protein
PMCN01_RS09265	COG3043	anaerobic respiration
PMCN01_RS09270	COG3005	denitrification pathway
PMCN01_RS09275	COG0758	DNA mediated transformation
PMCN01_RS09285	COG2818	Glycosylase
PMCN01_RS09310	COG0538	isocitrate dehydrogenase activity
PMCN01_RS09345	COG1238	metal cluster binding
PMCN01_RS09350	COG4942	peptidase
PMCN01_RS09350	COG1388	LysM domain
PMCN01_RS09375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PMCN01_RS09410	COG1794	racemase activity, acting on amino acids and derivatives
PMCN01_RS09415	COG3978	acetolactate synthase activity
PMCN01_RS09425	COG0561	phosphatase activity
PMCN01_RS09435	COG2267	carboxylic ester hydrolase activity
PMCN01_RS09440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PMCN01_RS09450	COG0561	phosphatase activity
PMCN01_RS09455	COG0235	Class ii aldolase
PMCN01_RS09460	COG3623	hexulose-6-phosphate isomerase
PMCN01_RS09465	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
PMCN01_RS09490	COG1129	ABC transporter
PMCN01_RS09495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PMCN01_RS09500	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PMCN01_RS09505	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PMCN01_RS09510	COG2731	YhcH YjgK YiaL family protein
PMCN01_RS09520	COG1414	Transcriptional regulator
PMCN01_RS09530	COG0477	Major facilitator Superfamily
PMCN01_RS09540	COG0351	phosphomethylpyrimidine kinase
PMCN01_RS09550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PMCN01_RS09555	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PMCN01_RS09560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PMCN01_RS09565	COG1116	anion transmembrane transporter activity
PMCN01_RS09580	COG0551	DNA topoisomerase type I activity
PMCN01_RS09595	COG1070	Carbohydrate kinase
PMCN01_RS09600	COG2390	Transcriptional regulator
PMCN01_RS09605	COG1129	ABC transporter
PMCN01_RS09650	COG0583	DNA-binding transcription factor activity
PMCN01_RS09660	COG3956	TIGRFAM MazG family protein
PMCN01_RS09680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PMCN01_RS09695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PMCN01_RS09700	COG2364	Membrane
PMCN01_RS09705	COG0859	PFAM glycosyl transferase family 9
PMCN01_RS09730	COG3069	C4-dicarboxylate transmembrane transporter activity
PMCN01_RS09735	COG1473	amidohydrolase
PMCN01_RS09745	COG4772	TonB-dependent receptor
PMCN01_RS09755	COG1132	(ABC) transporter
PMCN01_RS09760	COG0859	PFAM glycosyl transferase family 9
PMCN01_RS09775	COG1519	Transferase
PMCN01_RS09780	COG0463	Glycosyl transferase, family 2
PMCN01_RS09785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PMCN01_RS09790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PMCN01_RS09795	COG1120	ATPase activity
PMCN01_RS09800	COG0500	methyltransferase
PMCN01_RS09810	COG0456	acetyltransferase
PMCN01_RS09820	COG0762	integral membrane protein
PMCN01_RS09830	COG3171	Protein conserved in bacteria
PMCN01_RS09840	COG3038	cytochrome b561
PMCN01_RS09845	COG1194	a g-specific adenine glycosylase
PMCN01_RS09875	COG3056	Lipoprotein
PMCN01_RS09880	COG0271	Belongs to the BolA IbaG family
PMCN01_RS09885	COG1879	ABC-type sugar transport system periplasmic component
PMCN01_RS09890	COG1129	ABC transporter
PMCN01_RS09895	COG1172	Belongs to the binding-protein-dependent transport system permease family
PMCN01_RS09930	COG1477	protein flavinylation
PMCN01_RS09945	COG1230	cation diffusion facilitator family transporter
PMCN01_RS09950	COG2271	Major facilitator Superfamily
PMCN01_RS09960	COG2197	response regulator
PMCN01_RS09965	COG2271	Major facilitator Superfamily
PMCN01_RS09985	COG1309	transcriptional regulator
PMCN01_RS09990	COG0583	DNA-binding transcription factor activity
PMCN01_RS09995	COG0678	peroxiredoxin activity
PMCN01_RS09995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PMCN01_RS10005	COG0545	Peptidyl-prolyl cis-trans isomerase
PMCN01_RS10010	COG2964	Protein conserved in bacteria
PMCN01_RS10025	COG2168	tRNA wobble position uridine thiolation
PMCN01_RS10050	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PMCN01_RS10070	COG1929	Belongs to the glycerate kinase type-1 family
PMCN01_RS10075	COG2610	gluconate transmembrane transporter activity
PMCN01_RS10110	COG3068	Protein conserved in bacteria
PMCN01_RS10185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PMCN01_RS10190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PMCN01_RS10195	COG0006	proline dipeptidase activity
PMCN01_RS10215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PMCN01_RS10230	COG1496	oxidoreductase activity
PMCN01_RS10250	COG1737	Transcriptional regulator
PMCN01_RS10255	COG2731	YhcH YjgK YiaL family protein
PMCN01_RS10290	COG4232	protein-disulfide reductase activity
PMCN01_RS10320	COG1011	Hydrolase
PMCN01_RS10330	COG0697	spore germination
PMCN01_RS10335	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PMCN01_RS10355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PMCN01_RS10365	COG0805	protein transport
PMCN01_RS10405	COG1368	sulfuric ester hydrolase activity
PMCN01_RS10410	COG3119	arylsulfatase activity
PMCN01_RS10430	COG0641	radical SAM
PMCN01_RS10435	COG1253	flavin adenine dinucleotide binding
PMCN01_RS10445	COG0084	hydrolase, TatD family'
PMCN01_RS10450	COG0470	DNA polymerase III
PMCN01_RS10460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PMCN01_RS10465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PMCN01_RS10475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PMCN01_RS10495	COG1555	photosystem II stabilization
PMCN01_RS10515	COG0196	riboflavin kinase activity
PMCN01_RS10520	COG0728	peptidoglycan biosynthetic process
PMCN01_RS10535	COG0560	Phosphoserine phosphatase
PMCN01_RS10555	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PMCN01_RS10555	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PMCN01_RS10565	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PMCN01_RS10575	COG2376	Dihydroxyacetone kinase
PMCN01_RS10580	COG1461	Dihydroxyacetone kinase
PMCN01_RS10590	COG2390	Transcriptional regulator
PMCN01_RS10595	COG0698	ribose 5-phosphate isomerase
PMCN01_RS10600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PMCN01_RS10610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PMCN01_RS10635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PMCN01_RS10665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PMCN01_RS10670	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PMCN01_RS10685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PMCN01_RS10690	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PMCN01_RS10695	COG4972	Pilus assembly protein
PMCN01_RS10715	COG4796	Type ii and iii secretion system protein
PMCN01_RS10730	COG0338	D12 class N6 adenine-specific DNA methyltransferase
PMCN01_RS10735	COG4701	Protein of unknown function (DUF721)
PMCN01_RS10750	COG0494	nUDIX hydrolase
PMCN01_RS10760	COG1466	dna polymerase III delta subunit
PMCN01_RS10765	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
PMCN01_RS10785	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PMCN01_RS10795	COG2608	mercury ion transmembrane transporter activity
PMCN01_RS10805	COG1305	Transglutaminase-like
PMCN01_RS10815	COG5301	cellulose 1,4-beta-cellobiosidase activity
PMCN01_RS10925	COG4373	Mu-like prophage FluMu protein gp28
PMCN01_RS10935	COG0640	Transcriptional regulator
PMCN01_RS10960	COG3023	N-Acetylmuramoyl-L-alanine amidase
PMCN01_RS10980	COG4382	Mu-like prophage protein Gp16
PMCN01_RS11000	COG4396	Host-nuclease inhibitor protein Gam
PMCN01_RS11020	COG2842	Transposition protein
PMCN01_RS11025	COG2801	Transposase and inactivated derivatives
PMCN01_RS11030	COG3423	Transcriptional regulator
PMCN01_RS11045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PMCN01_RS11075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PMCN01_RS11080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PMCN01_RS11095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PMCN01_RS11100	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PMCN01_RS11105	COG4972	Pilus assembly protein
PMCN01_RS11125	COG4796	Type ii and iii secretion system protein
PMCN01_RS11140	COG0338	D12 class N6 adenine-specific DNA methyltransferase
PMCN01_RS11145	COG4701	Protein of unknown function (DUF721)
PMCN01_RS11160	COG0494	nUDIX hydrolase
PMCN01_RS11170	COG1466	dna polymerase III delta subunit
PMCN01_RS11175	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
PMCN01_RS11195	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PMCN01_RS11205	COG2608	mercury ion transmembrane transporter activity
PMCN01_RS11215	COG1305	Transglutaminase-like
PMCN01_RS11230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PMCN01_RS11265	COG3586	endonuclease activity
PMCN01_RS11305	COG2226	methyltransferase
PMCN01_RS11315	COG0814	amino acid
PMCN01_RS11325	COG4783	chaperone-mediated protein folding
PMCN01_RS11340	COG0848	biopolymer transport protein
PMCN01_RS11345	COG0811	peptide transport
PMCN01_RS11350	COG4536	flavin adenine dinucleotide binding
PMCN01_RS11355	COG4137	Cytochrome C assembly protein
PMCN01_RS11360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PMCN01_RS11410	COG1217	gtp-binding protein TYPA
PMCN01_RS11415	COG3739	integral membrane protein
PMCN01_RS11425	COG1720	tRNA m6t6A37 methyltransferase activity
PMCN01_RS11430	COG1575	Belongs to the MenA family. Type 1 subfamily
PMCN01_RS11440	COG0471	metal ion transport