locus-tag	class	description
BTV66_RS00035	COG4387	Mu-like prophage protein GP36
BTV66_RS00140	COG3392	D12 class N6 adenine-specific DNA methyltransferase
BTV66_RS00155	COG0019	diaminopimelate decarboxylase activity
BTV66_RS00160	COG0187	DNA topoisomerase II activity
BTV66_RS00170	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTV66_RS00185	COG0251	oxidation-reduction process
BTV66_RS00205	COG1560	Kdo2-lipid A biosynthetic process
BTV66_RS00210	COG0730	response to heat
BTV66_RS00215	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BTV66_RS00225	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BTV66_RS00225	COG3264	Mechanosensitive ion channel
BTV66_RS00230	COG0318	PFAM AMP-dependent synthetase and ligase
BTV66_RS00235	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BTV66_RS00240	COG0596	Alpha beta hydrolase
BTV66_RS00250	COG0716	FMN binding
BTV66_RS00255	COG0735	belongs to the Fur family
BTV66_RS00265	COG0697	spore germination
BTV66_RS00270	COG0697	spore germination
BTV66_RS00285	COG0142	geranyltranstransferase activity
BTV66_RS00290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BTV66_RS00310	COG1530	ribonuclease E activity
BTV66_RS00315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTV66_RS00325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTV66_RS00335	COG1629	transport
BTV66_RS00335	COG4771	TonB-dependent receptor
BTV66_RS00340	COG1823	symporter activity
BTV66_RS00355	COG0497	DNA recombination
BTV66_RS00375	COG1607	acyl-coa hydrolase
BTV66_RS00380	COG2350	Protein conserved in bacteria
BTV66_RS00385	COG0741	lytic transglycosylase activity
BTV66_RS00400	COG0633	Ferredoxin
BTV66_RS00415	COG0316	Belongs to the HesB IscA family
BTV66_RS00420	COG0822	iron-sulfur transferase activity
BTV66_RS00430	COG1959	2 iron, 2 sulfur cluster binding
BTV66_RS00435	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BTV66_RS00460	COG1518	maintenance of DNA repeat elements
BTV66_RS00495	COG0489	protein tyrosine kinase activity
BTV66_RS00505	COG1629	transport
BTV66_RS00505	COG4771	TonB-dependent receptor
BTV66_RS00510	COG0748	coenzyme F420 binding
BTV66_RS00590	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTV66_RS00600	COG1022	Amp-dependent synthetase and ligase
BTV66_RS00605	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BTV66_RS00610	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BTV66_RS00615	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BTV66_RS00625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BTV66_RS00645	COG3069	C4-dicarboxylate transmembrane transporter activity
BTV66_RS00655	COG2860	membrane
BTV66_RS00665	COG0527	aspartate kinase activity
BTV66_RS00675	COG1858	cytochrome C peroxidase
BTV66_RS00680	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BTV66_RS00680	COG1328	CTP reductase activity
BTV66_RS00695	COG0084	hydrolase, TatD family'
BTV66_RS00700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTV66_RS00705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTV66_RS00720	COG0800	Aldolase
BTV66_RS00725	COG0659	secondary active sulfate transmembrane transporter activity
BTV66_RS00755	COG1840	ABC-type Fe3 transport system, periplasmic component
BTV66_RS00760	COG1840	ABC-type Fe3 transport system, periplasmic component
BTV66_RS00765	COG1840	ABC-type Fe3 transport system, periplasmic component
BTV66_RS00785	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BTV66_RS00790	COG0456	acetyltransferase
BTV66_RS00795	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BTV66_RS00810	COG4795	General secretion pathway protein
BTV66_RS00815	COG2165	general secretion pathway protein
BTV66_RS00845	COG3064	Membrane
BTV66_RS00850	COG0848	biopolymer transport protein
BTV66_RS00855	COG0811	peptide transport
BTV66_RS00860	COG0824	Thioesterase
BTV66_RS00870	COG1294	oxidase, subunit
BTV66_RS00875	COG1271	oxidase subunit
BTV66_RS00910	COG0494	nUDIX hydrolase
BTV66_RS00925	COG1755	Isoprenylcysteine carboxyl methyltransferase
BTV66_RS00940	COG0346	lactoylglutathione lyase activity
BTV66_RS00950	COG2056	Na+-H+ antiporter family
BTV66_RS00965	COG1530	ribonuclease E activity
BTV66_RS00985	COG0626	cystathionine gamma-synthase activity
BTV66_RS01010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTV66_RS01035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTV66_RS01060	COG1086	Polysaccharide biosynthesis protein
BTV66_RS01080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTV66_RS01095	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BTV66_RS01105	COG1596	polysaccharide export
BTV66_RS01110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BTV66_RS01120	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BTV66_RS01125	COG0494	nUDIX hydrolase
BTV66_RS01130	COG1876	peptidase activity
BTV66_RS01140	COG1393	Belongs to the ArsC family
BTV66_RS01150	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BTV66_RS01175	COG1088	dTDP-glucose 4,6-dehydratase activity
BTV66_RS01195	COG2017	converts alpha-aldose to the beta-anomer
BTV66_RS01205	COG1085	galactose-1-phosphate uridylyltransferase
BTV66_RS01210	COG1609	Transcriptional regulator
BTV66_RS01215	COG1879	ABC-type sugar transport system periplasmic component
BTV66_RS01225	COG4211	Belongs to the binding-protein-dependent transport system permease family
BTV66_RS01230	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTV66_RS01235	COG2194	sulfuric ester hydrolase activity
BTV66_RS01245	COG1444	tRNA N-acetyltransferase activity
BTV66_RS01260	COG1702	phosphate starvation-inducible protein PhoH
BTV66_RS01265	COG0561	phosphatase activity
BTV66_RS01290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTV66_RS01305	COG1238	metal cluster binding
BTV66_RS01315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTV66_RS01340	COG0210	DNA helicase
BTV66_RS01345	COG5645	(Lipo)protein
BTV66_RS01360	COG3722	fumarate hydratase activity
BTV66_RS01365	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BTV66_RS01370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTV66_RS01370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTV66_RS01375	COG0861	Integral membrane protein TerC family
BTV66_RS01385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTV66_RS01395	COG3691	Protein conserved in bacteria
BTV66_RS01405	COG4178	(ABC) transporter
BTV66_RS01415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTV66_RS01430	COG4558	Periplasmic binding protein
BTV66_RS01435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTV66_RS01490	COG4145	pantothenate transmembrane transporter activity
BTV66_RS01495	COG3924	membrane
BTV66_RS01500	COG0439	Biotin carboxylase
BTV66_RS01505	COG0511	ligase activity, forming carbon-carbon bonds
BTV66_RS01535	COG4545	Glutaredoxin-related protein
BTV66_RS01555	COG1027	Aspartate ammonia-lyase
BTV66_RS01560	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BTV66_RS01580	COG0725	ABC transporter, periplasmic molybdate-binding protein
BTV66_RS01585	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BTV66_RS01590	COG3842	ATPase activity
BTV66_RS01600	COG0513	Belongs to the DEAD box helicase family
BTV66_RS01605	COG4785	May be involved in cell division
BTV66_RS01875	COG3617	BRO family, N-terminal domain
BTV66_RS01900	COG3723	Recombinational DNA repair protein, rece pathway
BTV66_RS02045	COG3036	rescue of stalled ribosome
BTV66_RS02050	COG1393	Belongs to the ArsC family
BTV66_RS02060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTV66_RS02065	COG1956	GAF domain-containing protein
BTV66_RS02070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTV66_RS02080	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BTV66_RS02085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BTV66_RS02090	COG0438	transferase activity, transferring glycosyl groups
BTV66_RS02095	COG1442	glycosyl transferase family 8
BTV66_RS02100	COG1216	Glycosyl transferase, family 2
BTV66_RS02115	COG3306	glycosyltransferase involved in LPS biosynthesis
BTV66_RS02135	COG1120	ATPase activity
BTV66_RS02140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTV66_RS02145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTV66_RS02165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTV66_RS02190	COG2226	methyltransferase
BTV66_RS02200	COG0592	DNA-directed DNA polymerase activity
BTV66_RS02245	COG1575	Belongs to the MenA family. Type 1 subfamily
BTV66_RS02250	COG1720	tRNA m6t6A37 methyltransferase activity
BTV66_RS02260	COG3739	integral membrane protein
BTV66_RS02265	COG1217	gtp-binding protein TYPA
BTV66_RS02315	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTV66_RS02320	COG4137	Cytochrome C assembly protein
BTV66_RS02325	COG4536	flavin adenine dinucleotide binding
BTV66_RS02330	COG0811	peptide transport
BTV66_RS02335	COG0848	biopolymer transport protein
BTV66_RS02350	COG4783	chaperone-mediated protein folding
BTV66_RS02360	COG0814	amino acid
BTV66_RS02365	COG0737	Belongs to the 5'-nucleotidase family
BTV66_RS02370	COG2226	methyltransferase
BTV66_RS02440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTV66_RS02455	COG1305	Transglutaminase-like
BTV66_RS02465	COG2608	mercury ion transmembrane transporter activity
BTV66_RS02475	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BTV66_RS02480	COG1466	dna polymerase III delta subunit
BTV66_RS02490	COG0494	nUDIX hydrolase
BTV66_RS02505	COG4701	Protein of unknown function (DUF721)
BTV66_RS02510	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BTV66_RS02525	COG4796	Type ii and iii secretion system protein
BTV66_RS02545	COG4972	Pilus assembly protein
BTV66_RS02550	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BTV66_RS02570	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BTV66_RS02575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTV66_RS02605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTV66_RS02630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTV66_RS02640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTV66_RS02645	COG0698	ribose 5-phosphate isomerase
BTV66_RS02650	COG2390	Transcriptional regulator
BTV66_RS02660	COG1461	Dihydroxyacetone kinase
BTV66_RS02665	COG2376	Dihydroxyacetone kinase
BTV66_RS02675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTV66_RS02685	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTV66_RS02685	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTV66_RS02705	COG0560	Phosphoserine phosphatase
BTV66_RS02725	COG0728	peptidoglycan biosynthetic process
BTV66_RS02730	COG0196	riboflavin kinase activity
BTV66_RS02750	COG1555	photosystem II stabilization
BTV66_RS02770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTV66_RS02780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTV66_RS02785	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BTV66_RS02795	COG0470	DNA polymerase III
BTV66_RS02800	COG0084	hydrolase, TatD family'
BTV66_RS02810	COG1253	flavin adenine dinucleotide binding
BTV66_RS02815	COG0641	radical SAM
BTV66_RS02835	COG3119	arylsulfatase activity
BTV66_RS02840	COG1368	sulfuric ester hydrolase activity
BTV66_RS02880	COG0805	protein transport
BTV66_RS02890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTV66_RS02910	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BTV66_RS02925	COG1011	Hydrolase
BTV66_RS02955	COG4232	protein-disulfide reductase activity
BTV66_RS02990	COG2731	YhcH YjgK YiaL family protein
BTV66_RS02995	COG1737	Transcriptional regulator
BTV66_RS03015	COG1496	oxidoreductase activity
BTV66_RS03030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTV66_RS03050	COG0006	proline dipeptidase activity
BTV66_RS03055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTV66_RS03060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTV66_RS03135	COG3068	Protein conserved in bacteria
BTV66_RS03170	COG2610	gluconate transmembrane transporter activity
BTV66_RS03175	COG1929	Belongs to the glycerate kinase type-1 family
BTV66_RS03195	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTV66_RS03220	COG2168	tRNA wobble position uridine thiolation
BTV66_RS03235	COG2964	Protein conserved in bacteria
BTV66_RS03240	COG0545	Peptidyl-prolyl cis-trans isomerase
BTV66_RS03250	COG0678	peroxiredoxin activity
BTV66_RS03250	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BTV66_RS03255	COG0583	DNA-binding transcription factor activity
BTV66_RS03260	COG1309	transcriptional regulator
BTV66_RS03265	COG1349	DNA-binding transcription factor activity
BTV66_RS03280	COG3392	D12 class N6 adenine-specific DNA methyltransferase
BTV66_RS03365	COG4386	tail sheath protein
BTV66_RS03385	COG4387	Mu-like prophage protein GP36
BTV66_RS03395	COG4397	Mu-like prophage major head subunit gpT
BTV66_RS03400	COG4388	Caudovirus prohead serine protease
BTV66_RS03405	COG5005	Phage virion morphogenesis
BTV66_RS03410	COG2369	cell adhesion
BTV66_RS03415	COG4383	Mu-like prophage protein gp29
BTV66_RS03455	COG3023	N-Acetylmuramoyl-L-alanine amidase
BTV66_RS03535	COG2801	Transposase and inactivated derivatives
BTV66_RS03540	COG3423	Transcriptional regulator
BTV66_RS03545	COG2932	Transcriptional regulator
BTV66_RS03555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BTV66_RS03555	COG4797	methyltransferase
BTV66_RS03565	COG4143	(ABC) transporter
BTV66_RS03585	COG0733	neurotransmitter:sodium symporter activity
BTV66_RS03590	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTV66_RS03645	COG1289	transmembrane transporter activity
BTV66_RS03650	COG3304	Inner membrane component domain
BTV66_RS03670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTV66_RS03675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTV66_RS03680	COG1121	(ABC) transporter
BTV66_RS03690	COG2920	part of a sulfur-relay system
BTV66_RS03705	COG0583	DNA-binding transcription factor activity
BTV66_RS03720	COG2864	formate dehydrogenase
BTV66_RS03725	COG0437	4 iron, 4 sulfur cluster binding
BTV66_RS03730	COG3383	formate dehydrogenase (NAD+) activity
BTV66_RS03730	COG0243	molybdopterin cofactor binding
BTV66_RS03735	COG0243	molybdopterin cofactor binding
BTV66_RS03735	COG3383	formate dehydrogenase (NAD+) activity
BTV66_RS03745	COG0210	DNA helicase
BTV66_RS03760	COG0463	Glycosyl transferase, family 2
BTV66_RS03795	COG0583	DNA-binding transcription factor activity
BTV66_RS03800	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BTV66_RS03805	COG1687	branched-chain amino acid
BTV66_RS03815	COG0488	(ABC) transporter
BTV66_RS03820	COG3683	transport system, periplasmic component
BTV66_RS03825	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BTV66_RS03850	COG5002	protein histidine kinase activity
BTV66_RS03855	COG0745	RESPONSE REGULATOR receiver
BTV66_RS03885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTV66_RS03890	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BTV66_RS03900	COG2062	phosphohistidine phosphatase, SixA
BTV66_RS03930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTV66_RS03935	COG4181	ATPase activity
BTV66_RS03945	COG0577	efflux transmembrane transporter activity
BTV66_RS03945	COG1136	(ABC) transporter
BTV66_RS03960	COG0672	)-iron permease
BTV66_RS03970	COG2837	iron assimilation
BTV66_RS03975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTV66_RS03990	COG0024	Methionine aminopeptidase
BTV66_RS04065	COG3593	DNA synthesis involved in DNA repair
BTV66_RS04080	COG3101	peptidyl-lysine hydroxylation
BTV66_RS04085	COG1131	(ABC) transporter
BTV66_RS04090	COG0842	Transport permease protein
BTV66_RS04095	COG2358	TRAP transporter, solute receptor (TAXI family
BTV66_RS04110	COG1611	Belongs to the LOG family
BTV66_RS04120	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BTV66_RS04125	COG3098	single-species biofilm formation
BTV66_RS04140	COG1278	Cold shock
BTV66_RS04150	COG1067	ATP-dependent peptidase activity
BTV66_RS04160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BTV66_RS04165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTV66_RS04265	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BTV66_RS04280	COG3306	glycosyltransferase involved in LPS biosynthesis
BTV66_RS04290	COG1216	Glycosyl transferase, family 2
BTV66_RS04300	COG2951	lytic endotransglycosylase activity
BTV66_RS04305	COG2252	PERMEase
BTV66_RS04310	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BTV66_RS04315	COG1074	ATP-dependent DNA helicase activity
BTV66_RS04320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BTV66_RS04325	COG2999	glutathione oxidoreductase activity
BTV66_RS04350	COG2969	positive regulation of protein catabolic process
BTV66_RS04355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BTV66_RS04360	COG0517	IMP dehydrogenase activity
BTV66_RS04360	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BTV66_RS04375	COG1538	Outer membrane efflux protein
BTV66_RS04385	COG1115	amino acid carrier protein
BTV66_RS04405	COG0142	geranyltranstransferase activity
BTV66_RS04440	COG1640	4-alpha-glucanotransferase
BTV66_RS04450	COG1523	belongs to the glycosyl hydrolase 13 family
BTV66_RS04480	COG1090	epimerase
BTV66_RS04500	COG3102	Protein conserved in bacteria
BTV66_RS04510	COG3133	Outer membrane lipoprotein
BTV66_RS04535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTV66_RS04540	COG4591	ABC-type transport system involved in lipoprotein release permease component
BTV66_RS04550	COG4591	ABC-type transport system involved in lipoprotein release permease component
BTV66_RS04555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BTV66_RS04560	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BTV66_RS04565	COG0402	S-adenosylhomocysteine deaminase activity
BTV66_RS04570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTV66_RS04575	COG0583	DNA-binding transcription factor activity
BTV66_RS04585	COG2833	Protein of unknown function (DUF455)
BTV66_RS04590	COG1946	Acyl-CoA thioesterase
BTV66_RS04600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BTV66_RS04605	COG4988	ABC transporter
BTV66_RS04610	COG0492	ferredoxin-NADP+ reductase activity
BTV66_RS04615	COG3118	belongs to the thioredoxin family
BTV66_RS04620	COG0288	reversible hydration of carbon dioxide
BTV66_RS04625	COG1629	transport
BTV66_RS04640	COG4221	oxidoreductase activity
BTV66_RS04660	COG0512	Glutamine amidotransferase of anthranilate synthase
BTV66_RS04665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BTV66_RS04670	COG0616	signal peptide processing
BTV66_RS04685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTV66_RS04705	COG0747	negative chemotaxis
BTV66_RS04725	COG0730	response to heat
BTV66_RS04730	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTV66_RS04735	COG3119	arylsulfatase activity
BTV66_RS04740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTV66_RS04745	COG0641	radical SAM
BTV66_RS04750	COG0676	glucose-6-phosphate 1-epimerase activity
BTV66_RS04760	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BTV66_RS04805	COG0697	spore germination
BTV66_RS04810	COG2925	Exonuclease
BTV66_RS04815	COG4575	ribosome binding
BTV66_RS04835	COG0613	PHP domain protein
BTV66_RS04845	COG0308	aminopeptidase N
BTV66_RS04850	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTV66_RS04855	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BTV66_RS04860	COG1448	Aminotransferase
BTV66_RS04870	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BTV66_RS04890	COG0791	NLP P60 protein
BTV66_RS04920	COG0564	pseudouridine synthase activity
BTV66_RS04925	COG0406	alpha-ribazole phosphatase activity
BTV66_RS04930	COG0285	dihydrofolate synthase activity
BTV66_RS04955	COG0586	Pfam SNARE associated Golgi protein
BTV66_RS04965	COG1940	carbohydrate kinase activity
BTV66_RS04975	COG4953	penicillin-binding protein 1C
BTV66_RS04995	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BTV66_RS05000	COG2823	Periplasmic or secreted lipoprotein
BTV66_RS05005	COG0307	riboflavin synthase, alpha
BTV66_RS05015	COG0673	inositol 2-dehydrogenase activity
BTV66_RS05020	COG0469	pyruvate kinase activity
BTV66_RS05055	COG0583	DNA-binding transcription factor activity
BTV66_RS05065	COG0009	L-threonylcarbamoyladenylate synthase
BTV66_RS05070	COG4409	exo-alpha-(2->6)-sialidase activity
BTV66_RS05080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BTV66_RS05085	COG1528	Iron-storage protein
BTV66_RS05090	COG1528	Iron-storage protein
BTV66_RS05100	COG0589	response to stress
BTV66_RS05110	COG0616	signal peptide processing
BTV66_RS05115	COG0778	Nitroreductase
BTV66_RS05120	COG0515	serine threonine protein kinase
BTV66_RS05135	COG0671	phosphoesterase, PA-phosphatase related
BTV66_RS05145	COG4166	transmembrane transport
BTV66_RS05150	COG2832	Protein of unknown function (DUF454)
BTV66_RS05155	COG0339	signal peptide processing
BTV66_RS05185	COG1846	Transcriptional regulator
BTV66_RS05185	COG1940	carbohydrate kinase activity
BTV66_RS05205	COG1944	ATP diphosphatase activity
BTV66_RS05210	COG3105	Protein conserved in bacteria
BTV66_RS05225	COG0708	Exodeoxyribonuclease III
BTV66_RS05240	COG0303	'Molybdopterin
BTV66_RS05245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTV66_RS05270	COG0163	prenyltransferase activity
BTV66_RS05280	COG1286	toxin biosynthetic process
BTV66_RS05295	COG0857	belongs to the CobB CobQ family
BTV66_RS05295	COG0280	phosphate acetyltransferase
BTV66_RS05310	COG3065	identical protein binding
BTV66_RS05315	COG1214	PFAM Peptidase M22, glycoprotease
BTV66_RS05320	COG1199	ATP-dependent helicase activity
BTV66_RS05325	COG0676	glucose-6-phosphate 1-epimerase activity
BTV66_RS05335	COG1534	Rna-binding protein
BTV66_RS05350	COG2027	D-alanyl-D-alanine carboxypeptidase
BTV66_RS05355	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTV66_RS05360	COG0733	neurotransmitter:sodium symporter activity
BTV66_RS05370	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTV66_RS05375	COG0633	Ferredoxin
BTV66_RS05410	COG1280	lysine exporter protein (LysE YggA)
BTV66_RS05415	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BTV66_RS05420	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BTV66_RS05435	COG0814	amino acid
BTV66_RS05445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTV66_RS05450	COG5339	Protein conserved in bacteria
BTV66_RS05465	COG2873	o-acetylhomoserine
BTV66_RS05480	COG1629	transport
BTV66_RS05480	COG4771	TonB-dependent receptor
BTV66_RS05490	COG4149	molybdate abc transporter
BTV66_RS05495	COG0725	ABC transporter, periplasmic molybdate-binding protein
BTV66_RS05505	COG2005	Transcriptional regulator
BTV66_RS05515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTV66_RS05520	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTV66_RS05520	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTV66_RS05535	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BTV66_RS05540	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BTV66_RS05580	COG0195	Participates in both transcription termination and antitermination
BTV66_RS05615	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BTV66_RS05635	COG1643	Atp-dependent helicase
BTV66_RS05640	COG2363	Small membrane protein
BTV66_RS05675	COG0463	Glycosyl transferase, family 2
BTV66_RS05705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BTV66_RS05715	COG1704	LemA family
BTV66_RS05725	COG0247	lactate metabolic process
BTV66_RS05725	COG0277	FAD linked oxidase domain protein
BTV66_RS05745	COG1609	Transcriptional regulator
BTV66_RS05750	COG3265	gluconokinase activity
BTV66_RS05755	COG2610	gluconate transmembrane transporter activity
BTV66_RS05760	COG0626	cystathionine gamma-synthase activity
BTV66_RS05765	COG0450	alkyl hydroperoxide reductase
BTV66_RS05770	COG0023	Translation Initiation Factor
BTV66_RS05780	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BTV66_RS05785	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BTV66_RS05795	COG0539	negative regulation of cytoplasmic translation
BTV66_RS05805	COG4771	TonB-dependent receptor
BTV66_RS05810	COG0612	Peptidase, M16
BTV66_RS05820	COG1982	Orn Lys Arg decarboxylase major
BTV66_RS05825	COG0531	amino acid
BTV66_RS05835	COG2990	Protein conserved in bacteria
BTV66_RS05840	COG0814	amino acid
BTV66_RS05860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTV66_RS05875	COG0783	Belongs to the Dps family
BTV66_RS05905	COG2927	DNA polymerase III (CHI subunit)
BTV66_RS05915	COG2268	Band 7 protein
BTV66_RS05930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BTV66_RS05955	COG3716	PTS system mannose fructose sorbose family IID component
BTV66_RS05960	COG3715	PTS system
BTV66_RS05965	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTV66_RS05965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTV66_RS05970	COG2814	Major facilitator Superfamily
BTV66_RS06000	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTV66_RS06005	COG3094	Invasion gene expression up-regulator, SirB
BTV66_RS06055	COG1450	Type ii and iii secretion system protein
BTV66_RS06080	COG4974	Belongs to the 'phage' integrase family
BTV66_RS06160	COG4695	Portal protein
BTV66_RS06250	COG5301	cellulose 1,4-beta-cellobiosidase activity
BTV66_RS06300	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTV66_RS06330	COG0658	competence protein
BTV66_RS06330	COG2333	competence protein COMEC
BTV66_RS06340	COG0617	tRNA 3'-terminal CCA addition
BTV66_RS06345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BTV66_RS06355	COG2949	membrane
BTV66_RS06365	COG0440	acetolactate synthase activity
BTV66_RS06370	COG0028	Belongs to the TPP enzyme family
BTV66_RS06375	COG1757	Na H antiporter
BTV66_RS06385	COG0788	formyltetrahydrofolate deformylase activity
BTV66_RS06390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BTV66_RS06405	COG1263	PTS System
BTV66_RS06405	COG2190	(PTS) system
BTV66_RS06405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTV66_RS06410	COG0488	(ABC) transporter
BTV66_RS06420	COG1346	cytolysis
BTV66_RS06430	COG1525	nuclease
BTV66_RS06440	COG2166	iron-sulfur cluster assembly
BTV66_RS06450	COG1560	Kdo2-lipid A biosynthetic process
BTV66_RS06455	COG3381	protein complex oligomerization
BTV66_RS06460	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTV66_RS06470	COG0330	HflC and HflK could
BTV66_RS06475	COG1119	ATPase activity
BTV66_RS06485	COG2932	Transcriptional regulator
BTV66_RS06490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTV66_RS06495	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTV66_RS06500	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BTV66_RS06505	COG2190	(PTS) system
BTV66_RS06515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTV66_RS06540	COG0802	atpase or kinase
BTV66_RS06545	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTV66_RS06545	COG1388	LysM domain
BTV66_RS06565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTV66_RS06570	COG3283	Transcriptional regulator of aromatic amino acids metabolism
BTV66_RS06580	COG3106	COG3106 Predicted ATPase
BTV66_RS06585	COG4166	transmembrane transport
BTV66_RS06590	COG4168	peptide transport system, permease
BTV66_RS06595	COG4171	peptide transport system, permease
BTV66_RS06600	COG4172	Belongs to the ABC transporter superfamily
BTV66_RS06645	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BTV66_RS06645	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BTV66_RS06695	COG2252	PERMEase
BTV66_RS06705	COG2814	Major facilitator Superfamily
BTV66_RS06725	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BTV66_RS06740	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTV66_RS06745	COG0567	Dehydrogenase, E1 component
BTV66_RS06770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTV66_RS06775	COG3108	Peptidase M15
BTV66_RS06780	COG2989	Protein conserved in bacteria
BTV66_RS06785	COG0793	Belongs to the peptidase S41A family
BTV66_RS06795	COG2995	paraquat-inducible protein a
BTV66_RS06800	COG3008	intermembrane lipid transfer
BTV66_RS06815	COG1176	ABC-type spermidine putrescine transport system, permease component I
BTV66_RS06820	COG1177	transmembrane transport
BTV66_RS06825	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BTV66_RS06830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BTV66_RS06845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BTV66_RS06860	COG1522	sequence-specific DNA binding
BTV66_RS06870	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BTV66_RS06880	COG1392	Phosphate transport regulator
BTV66_RS06885	COG0306	phosphate transporter
BTV66_RS06890	COG4991	sh3 domain protein
BTV66_RS06915	COG0739	heme binding
BTV66_RS06925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTV66_RS06930	COG4608	Belongs to the ABC transporter superfamily
BTV66_RS06935	COG0444	Belongs to the ABC transporter superfamily
BTV66_RS06940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTV66_RS06945	COG0601	transmembrane transport
BTV66_RS06950	COG0747	negative chemotaxis
BTV66_RS06955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BTV66_RS06965	COG0826	peptidase U32
BTV66_RS06975	COG0561	phosphatase activity
BTV66_RS06980	COG3069	C4-dicarboxylate transmembrane transporter activity
BTV66_RS06990	COG1862	Preprotein translocase
BTV66_RS06995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTV66_RS07000	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTV66_RS07035	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BTV66_RS07040	COG0745	RESPONSE REGULATOR receiver
BTV66_RS07055	COG3585	molybdate ion transport
BTV66_RS07060	COG0642	Histidine kinase
BTV66_RS07065	COG0745	RESPONSE REGULATOR receiver
BTV66_RS07070	COG2259	Doxx family
BTV66_RS07085	COG3219	Protein conserved in bacteria
BTV66_RS07095	COG1595	DNA-templated transcription, initiation
BTV66_RS07140	COG1053	succinate dehydrogenase
BTV66_RS07145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BTV66_RS07160	COG0795	lipopolysaccharide-transporting ATPase activity
BTV66_RS07165	COG0795	lipopolysaccharide-transporting ATPase activity
BTV66_RS07180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BTV66_RS07185	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BTV66_RS07210	COG1083	cytidylyl-transferase
BTV66_RS07220	COG0720	synthase
BTV66_RS07225	COG0602	queuosine metabolic process
BTV66_RS07235	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BTV66_RS07250	COG5007	Belongs to the BolA IbaG family
BTV66_RS07255	COG3113	response to antibiotic
BTV66_RS07260	COG2854	intermembrane phospholipid transfer
BTV66_RS07265	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BTV66_RS07270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BTV66_RS07275	COG1127	ABC transporter
BTV66_RS07280	COG3117	lipopolysaccharide transmembrane transporter activity
BTV66_RS07285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BTV66_RS07290	COG1137	ATPase activity
BTV66_RS07295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTV66_RS07310	COG2850	peptidyl-arginine hydroxylation
BTV66_RS07320	COG2867	negative regulation of translational initiation
BTV66_RS07335	COG0531	amino acid
BTV66_RS07345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTV66_RS07350	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BTV66_RS07355	COG2824	Alkylphosphonate utilization operon protein PhnA
BTV66_RS07375	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTV66_RS07380	COG1879	ABC-type sugar transport system periplasmic component
BTV66_RS07385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTV66_RS07395	COG0077	Prephenate dehydratase
BTV66_RS07395	COG1605	Chorismate mutase
BTV66_RS07400	COG1979	alcohol dehydrogenase
BTV66_RS07410	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BTV66_RS07415	COG0849	cell division
BTV66_RS07420	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BTV66_RS07455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BTV66_RS07465	COG0768	penicillin binding
BTV66_RS07470	COG3116	cell division
BTV66_RS07485	COG1966	Carbon starvation protein
BTV66_RS07490	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BTV66_RS07500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTV66_RS07505	COG1120	ATPase activity
BTV66_RS07520	COG4215	(ABC) transporter
BTV66_RS07525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTV66_RS07540	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTV66_RS07545	COG0312	modulator of DNA gyrase
BTV66_RS07555	COG0330	HflC and HflK could
BTV66_RS07560	COG0330	HflC and HflK could
BTV66_RS07570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BTV66_RS07580	COG0460	homoserine dehydrogenase
BTV66_RS07580	COG0527	aspartate kinase activity
BTV66_RS07650	COG0204	Acyl-transferase
BTV66_RS07660	COG5413	integral membrane protein
BTV66_RS07670	COG1509	lysine 2,3-aminomutase activity
BTV66_RS07675	COG3061	Opacity-associated protein A
BTV66_RS07675	COG3266	domain, Protein
BTV66_RS07695	COG2814	Major facilitator Superfamily
BTV66_RS07705	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BTV66_RS07710	COG1115	amino acid carrier protein
BTV66_RS07735	COG1459	type II secretion system
BTV66_RS07740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BTV66_RS07745	COG4969	Belongs to the N-Me-Phe pilin family
BTV66_RS07750	COG3023	N-Acetylmuramoyl-L-alanine amidase
BTV66_RS07760	COG0730	response to heat
BTV66_RS07775	COG0590	tRNA wobble adenosine to inosine editing
BTV66_RS07780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BTV66_RS07790	COG1882	Formate acetyltransferase
BTV66_RS07795	COG2116	formate transmembrane transporter activity
BTV66_RS07800	COG0537	adenosine 5'-monophosphoramidase activity
BTV66_RS07825	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTV66_RS07855	COG0681	Belongs to the peptidase S26 family
BTV66_RS07885	COG2267	carboxylic ester hydrolase activity
BTV66_RS07900	COG0436	Aminotransferase
BTV66_RS07915	COG3842	ATPase activity
BTV66_RS07940	COG2095	MarC family integral membrane protein
BTV66_RS07945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTV66_RS07950	COG0748	coenzyme F420 binding
BTV66_RS07955	COG4178	(ABC) transporter
BTV66_RS07970	COG0121	glutamine amidotransferase
BTV66_RS07975	COG0814	amino acid
BTV66_RS07980	COG1760	l-serine dehydratase
BTV66_RS07985	COG3738	Protein conserved in bacteria
BTV66_RS08000	COG0753	catalase activity
BTV66_RS08005	COG2081	HI0933 family
BTV66_RS08010	COG3088	subunit of a heme lyase
BTV66_RS08010	COG4235	cytochrome complex assembly
BTV66_RS08015	COG3088	subunit of a heme lyase
BTV66_RS08015	COG4235	cytochrome complex assembly
BTV66_RS08025	COG1138	Cytochrome C-type biogenesis protein
BTV66_RS08030	COG3301	Polysulphide reductase, NrfD
BTV66_RS08035	COG0437	4 iron, 4 sulfur cluster binding
BTV66_RS08040	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BTV66_RS08060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BTV66_RS08075	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTV66_RS08090	COG0346	lactoylglutathione lyase activity
BTV66_RS08110	COG1138	Cytochrome C-type biogenesis protein
BTV66_RS08120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTV66_RS08125	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTV66_RS08130	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTV66_RS08140	COG2814	Major facilitator Superfamily
BTV66_RS08150	COG0281	malic enzyme
BTV66_RS08150	COG0280	phosphate acetyltransferase
BTV66_RS08165	COG0737	Belongs to the 5'-nucleotidase family
BTV66_RS08175	COG2976	Protein conserved in bacteria
BTV66_RS08190	COG1426	Protein conserved in bacteria
BTV66_RS08195	COG3063	Type IV pilus biogenesis stability protein PilW
BTV66_RS08210	COG0628	permease
BTV66_RS08220	COG0521	Mo-molybdopterin cofactor biosynthetic process
BTV66_RS08225	COG4589	Belongs to the CDS family
BTV66_RS08235	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTV66_RS08240	COG0471	metal ion transport
BTV66_RS08240	COG0490	domain, Protein
BTV66_RS08285	COG0575	Belongs to the CDS family
BTV66_RS08320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTV66_RS08325	COG0842	Transport permease protein
BTV66_RS08325	COG1129	ABC transporter
BTV66_RS08330	COG0842	Transport permease protein
BTV66_RS08335	COG1538	Outer membrane efflux protein
BTV66_RS08340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTV66_RS08345	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BTV66_RS08365	COG1652	LysM domain
BTV66_RS08370	COG2321	neutral zinc metallopeptidase
BTV66_RS08375	COG3730	PTS system glucitol sorbitol-specific
BTV66_RS08390	COG1028	Short-chain dehydrogenase reductase Sdr
BTV66_RS08395	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTV66_RS08400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTV66_RS08440	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BTV66_RS08445	COG1792	Involved in formation and maintenance of cell shape
BTV66_RS08455	COG0557	exoribonuclease II activity
BTV66_RS08515	COG0798	PFAM Bile acid sodium symporter
BTV66_RS08525	COG0789	Transcriptional regulator
BTV66_RS08545	COG2132	Multicopper oxidase
BTV66_RS08615	COG1686	Belongs to the peptidase S11 family
BTV66_RS08625	COG0772	Belongs to the SEDS family
BTV66_RS08630	COG0768	penicillin binding
BTV66_RS08640	COG0799	negative regulation of ribosome biogenesis
BTV66_RS08650	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BTV66_RS08660	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BTV66_RS08670	COG1028	Short-chain dehydrogenase reductase Sdr
BTV66_RS08675	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BTV66_RS08695	COG1399	metal-binding, possibly nucleic acid-binding protein
BTV66_RS08705	COG0601	transmembrane transport
BTV66_RS08720	COG4608	Belongs to the ABC transporter superfamily
BTV66_RS08735	COG0500	methyltransferase
BTV66_RS08740	COG2830	Protein of unknown function (DUF452)
BTV66_RS08750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTV66_RS08760	COG0545	Peptidyl-prolyl cis-trans isomerase
BTV66_RS08775	COG2966	Psort location CytoplasmicMembrane, score
BTV66_RS08780	COG3610	response to peptide
BTV66_RS08785	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BTV66_RS08790	COG2217	Heavy metal translocating P-type atpase
BTV66_RS08795	COG2608	mercury ion transmembrane transporter activity
BTV66_RS08805	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BTV66_RS08810	COG2205	protein histidine kinase activity
BTV66_RS08815	COG0745	RESPONSE REGULATOR receiver
BTV66_RS08820	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTV66_RS08835	COG3083	sulfuric ester hydrolase activity
BTV66_RS08840	COG0402	S-adenosylhomocysteine deaminase activity
BTV66_RS08845	COG1011	Hydrolase
BTV66_RS08875	COG1561	YicC-like family, N-terminal region
BTV66_RS08910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BTV66_RS08930	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BTV66_RS08940	COG0191	fructose-bisphosphate aldolase activity
BTV66_RS08950	COG3719	Belongs to the RNase T2 family
BTV66_RS08955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BTV66_RS08960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTV66_RS08965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTV66_RS08970	COG1556	Lactate utilization protein
BTV66_RS08975	COG1139	Iron-sulfur cluster binding protein
BTV66_RS08980	COG0247	lactate metabolic process
BTV66_RS08985	COG1620	l-lactate permease
BTV66_RS08990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTV66_RS09000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTV66_RS09005	COG1621	beta-fructofuranosidase activity
BTV66_RS09025	COG0859	PFAM glycosyl transferase family 9
BTV66_RS09030	COG0859	PFAM glycosyl transferase family 9
BTV66_RS09035	COG0513	Belongs to the DEAD box helicase family
BTV66_RS09045	COG3201	nicotinamide mononucleotide transporter
BTV66_RS09070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTV66_RS09075	COG0778	Nitroreductase
BTV66_RS09110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BTV66_RS09120	COG1136	(ABC) transporter
BTV66_RS09120	COG0577	efflux transmembrane transporter activity
BTV66_RS09160	COG3071	HemY protein
BTV66_RS09165	COG2959	enzyme of heme biosynthesis
BTV66_RS09185	COG2197	response regulator
BTV66_RS09190	COG0729	surface antigen
BTV66_RS09195	COG2911	Protein conserved in bacteria
BTV66_RS09200	COG0248	Ppx GppA phosphatase
BTV66_RS09225	COG3085	chromosome segregation
BTV66_RS09230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BTV66_RS09235	COG3084	Protein conserved in bacteria
BTV66_RS09250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTV66_RS09250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTV66_RS09255	COG1105	Belongs to the carbohydrate kinase PfkB family
BTV66_RS09260	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BTV66_RS09260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTV66_RS09260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTV66_RS09275	COG3005	denitrification pathway
BTV66_RS09285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTV66_RS09295	COG1595	DNA-templated transcription, initiation
BTV66_RS09305	COG3026	antisigma factor binding
BTV66_RS09310	COG3086	response to oxidative stress
BTV66_RS09315	COG1763	Mo-molybdopterin cofactor biosynthetic process
BTV66_RS09320	COG2814	Major facilitator Superfamily
BTV66_RS09400	COG0582	viral genome integration into host DNA
BTV66_RS09410	COG1957	nucleoside hydrolase
BTV66_RS09415	COG3276	selenocysteine insertion sequence binding
BTV66_RS09425	COG2186	Transcriptional regulator
BTV66_RS09430	COG3842	ATPase activity
BTV66_RS09440	COG1175	transmembrane transport
BTV66_RS09450	COG0673	inositol 2-dehydrogenase activity
BTV66_RS09455	COG2221	Nitrite and sulphite reductase 4Fe-4S
BTV66_RS09455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BTV66_RS09460	COG3381	protein complex oligomerization
BTV66_RS09465	COG3302	dmso reductase anchor subunit
BTV66_RS09470	COG0437	4 iron, 4 sulfur cluster binding
BTV66_RS09475	COG0243	molybdopterin cofactor binding
BTV66_RS09480	COG1285	pathogenesis
BTV66_RS09485	COG2190	(PTS) system
BTV66_RS09485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTV66_RS09485	COG1263	PTS System
BTV66_RS09545	COG2610	gluconate transmembrane transporter activity
BTV66_RS09550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTV66_RS09555	COG1073	alpha beta
BTV66_RS09565	COG3622	Belongs to the hyi family
BTV66_RS09570	COG0235	Class ii aldolase
BTV66_RS09575	COG3395	kinase activity
BTV66_RS09580	COG2084	Dehydrogenase
BTV66_RS09585	COG1349	DNA-binding transcription factor activity
BTV66_RS09590	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTV66_RS09605	COG1070	Carbohydrate kinase
BTV66_RS09625	COG1940	carbohydrate kinase activity
BTV66_RS09640	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTV66_RS09650	COG0784	Response regulator, receiver
BTV66_RS09650	COG4191	Histidine kinase
BTV66_RS09665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTV66_RS09670	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BTV66_RS09680	COG2960	long-chain fatty acid transporting porin activity
BTV66_RS09685	COG3172	ATPase kinase involved in NAD metabolism
BTV66_RS09690	COG2129	metallophosphoesterase
BTV66_RS09725	COG0201	protein transport
BTV66_RS09805	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BTV66_RS09830	COG0051	transcription antitermination factor activity, RNA binding
BTV66_RS09835	COG0038	chloride channel
BTV66_RS09845	COG0814	amino acid
BTV66_RS09875	COG0019	diaminopimelate decarboxylase activity
BTV66_RS09885	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BTV66_RS09900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BTV66_RS09920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTV66_RS09925	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BTV66_RS09930	COG0433	COG0433 Predicted ATPase
BTV66_RS09945	COG0705	Rhomboid family
BTV66_RS09950	COG1349	DNA-binding transcription factor activity
BTV66_RS09955	COG0247	lactate metabolic process
BTV66_RS09965	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BTV66_RS09970	COG2271	Major facilitator Superfamily
BTV66_RS09975	COG0584	glycerophosphoryl diester phosphodiesterase
BTV66_RS09980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BTV66_RS09995	COG2183	response to ionizing radiation
BTV66_RS10015	COG1584	GPR1 FUN34 yaaH family protein
BTV66_RS10020	COG1012	belongs to the aldehyde dehydrogenase family
BTV66_RS10020	COG1454	alcohol dehydrogenase
BTV66_RS10025	COG3842	ATPase activity
BTV66_RS10030	COG1178	ABC-type Fe3 transport system permease component
BTV66_RS10035	COG3842	ATPase activity
BTV66_RS10075	COG0512	Glutamine amidotransferase of anthranilate synthase
BTV66_RS10085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTV66_RS10110	COG1881	PFAM PEBP family protein
BTV66_RS10115	COG1733	regulation of RNA biosynthetic process
BTV66_RS10125	COG1132	(ABC) transporter
BTV66_RS10130	COG4988	ABC transporter
BTV66_RS10135	COG0697	spore germination
BTV66_RS10140	COG0187	DNA topoisomerase II activity
BTV66_RS10160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTV66_RS10165	COG0640	Transcriptional regulator
BTV66_RS10170	COG1494	fructose-1,6-bisphosphatase
BTV66_RS10245	COG1739	Uncharacterized protein family UPF0029
BTV66_RS10250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTV66_RS10295	COG2853	Lipoprotein
BTV66_RS10325	COG4942	peptidase
BTV66_RS10330	COG2861	carbohydrate metabolic process
BTV66_RS10340	COG1629	transport
BTV66_RS10340	COG4206	TonB-dependent receptor
BTV66_RS10345	COG0606	chelatase, subunit chli
BTV66_RS10355	COG2990	Protein conserved in bacteria
BTV66_RS10360	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BTV66_RS10375	COG0742	ribosomal rna small subunit methyltransferase
BTV66_RS10390	COG0552	protein localization to endoplasmic reticulum
BTV66_RS10395	COG2884	Cell division ATP-binding protein ftsE
BTV66_RS10400	COG2177	Part of the ABC transporter FtsEX involved in
BTV66_RS10445	COG1012	belongs to the aldehyde dehydrogenase family
BTV66_RS10450	COG3384	dioxygenase
BTV66_RS10460	COG2814	Major facilitator Superfamily
BTV66_RS10465	COG3971	2-oxopent-4-enoate hydratase activity
BTV66_RS10480	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BTV66_RS10485	COG0732	type I restriction modification DNA specificity domain
BTV66_RS10500	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BTV66_RS10515	COG0494	nUDIX hydrolase
BTV66_RS10520	COG1011	Hydrolase
BTV66_RS10525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BTV66_RS10535	COG1218	3'(2'),5'-bisphosphate nucleotidase
BTV66_RS10540	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTV66_RS10545	COG0363	glucosamine-6-phosphate deaminase activity
BTV66_RS10550	COG0625	glutathione transferase activity
BTV66_RS10575	COG1040	competence protein
BTV66_RS10625	COG1215	transferase activity, transferring glycosyl groups
BTV66_RS10630	COG0569	domain protein
BTV66_RS10640	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BTV66_RS10655	COG2841	Protein conserved in bacteria
BTV66_RS10660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BTV66_RS10675	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BTV66_RS10680	COG1522	sequence-specific DNA binding
BTV66_RS10705	COG2358	TRAP transporter, solute receptor (TAXI family
BTV66_RS10720	COG2095	MarC family integral membrane protein
BTV66_RS10725	COG0488	(ABC) transporter
BTV66_RS10735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTV66_RS10740	COG0471	metal ion transport
BTV66_RS10745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTV66_RS10750	COG1275	C4-dicarboxylate transporter malic acid transport protein
BTV66_RS10770	COG3850	Histidine kinase
BTV66_RS10775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BTV66_RS10780	COG3062	negative regulation of establishment of protein localization
BTV66_RS10790	COG0437	4 iron, 4 sulfur cluster binding
BTV66_RS10800	COG3043	anaerobic respiration
BTV66_RS10805	COG3005	denitrification pathway
BTV66_RS10810	COG0758	DNA mediated transformation
BTV66_RS10820	COG2818	Glycosylase
BTV66_RS10845	COG0538	isocitrate dehydrogenase activity
BTV66_RS10880	COG1238	metal cluster binding
BTV66_RS10885	COG4942	peptidase
BTV66_RS10885	COG1388	LysM domain
BTV66_RS10910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BTV66_RS10945	COG1794	racemase activity, acting on amino acids and derivatives
BTV66_RS10950	COG3978	acetolactate synthase activity
BTV66_RS10960	COG0561	phosphatase activity
BTV66_RS10970	COG2267	carboxylic ester hydrolase activity
BTV66_RS10975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTV66_RS11010	COG0561	phosphatase activity
BTV66_RS11015	COG0235	Class ii aldolase
BTV66_RS11020	COG3623	hexulose-6-phosphate isomerase
BTV66_RS11025	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BTV66_RS11050	COG1129	ABC transporter
BTV66_RS11055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTV66_RS11060	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTV66_RS11065	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTV66_RS11070	COG2731	YhcH YjgK YiaL family protein
BTV66_RS11080	COG1414	Transcriptional regulator
BTV66_RS11090	COG0477	Major facilitator Superfamily
BTV66_RS11100	COG0351	phosphomethylpyrimidine kinase
BTV66_RS11110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTV66_RS11115	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BTV66_RS11120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTV66_RS11125	COG1116	anion transmembrane transporter activity
BTV66_RS11140	COG0551	DNA topoisomerase type I activity
BTV66_RS11155	COG1070	Carbohydrate kinase
BTV66_RS11160	COG2390	Transcriptional regulator
BTV66_RS11165	COG1129	ABC transporter
BTV66_RS11210	COG0583	DNA-binding transcription factor activity
BTV66_RS11220	COG3956	TIGRFAM MazG family protein
BTV66_RS11240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTV66_RS11255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTV66_RS11260	COG2364	Membrane
BTV66_RS11265	COG0859	PFAM glycosyl transferase family 9
BTV66_RS11290	COG3069	C4-dicarboxylate transmembrane transporter activity
BTV66_RS11295	COG1473	amidohydrolase
BTV66_RS11300	COG1132	(ABC) transporter
BTV66_RS11305	COG0859	PFAM glycosyl transferase family 9
BTV66_RS11320	COG1519	Transferase
BTV66_RS11325	COG0463	Glycosyl transferase, family 2
BTV66_RS11330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTV66_RS11335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTV66_RS11340	COG1120	ATPase activity
BTV66_RS11345	COG0500	methyltransferase
BTV66_RS11355	COG0456	acetyltransferase
BTV66_RS11365	COG0762	integral membrane protein
BTV66_RS11375	COG3171	Protein conserved in bacteria
BTV66_RS11385	COG3038	cytochrome b561
BTV66_RS11390	COG1194	a g-specific adenine glycosylase
BTV66_RS11420	COG3056	Lipoprotein
BTV66_RS11425	COG0271	Belongs to the BolA IbaG family
BTV66_RS11430	COG1879	ABC-type sugar transport system periplasmic component
BTV66_RS11435	COG1129	ABC transporter
BTV66_RS11440	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTV66_RS11475	COG1477	protein flavinylation
BTV66_RS11490	COG1230	cation diffusion facilitator family transporter
BTV66_RS11505	COG2197	response regulator
BTV66_RS11510	COG2271	Major facilitator Superfamily
BTV66_RS11520	COG3423	Transcriptional regulator
BTV66_RS11605	COG3023	N-Acetylmuramoyl-L-alanine amidase
BTV66_RS11645	COG4383	Mu-like prophage protein gp29
BTV66_RS11650	COG2369	cell adhesion
BTV66_RS11655	COG5005	Phage virion morphogenesis
BTV66_RS11660	COG4388	Caudovirus prohead serine protease
BTV66_RS11665	COG4397	Mu-like prophage major head subunit gpT
BTV66_RS11675	COG4387	Mu-like prophage protein GP36
BTV66_RS11760	COG2861	carbohydrate metabolic process
BTV66_RS11955	COG4168	peptide transport system, permease
BTV66_RS12040	COG0363	glucosamine-6-phosphate deaminase activity