locus-tag	class	description
A4G20_RS00010	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A4G20_RS00015	ENOG4105D06	uba thif-type nad fad binding protein
A4G20_RS00025	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A4G20_RS00030	ENOG410804X	Transcriptional regulator
A4G20_RS00035	ENOG4105DFA	alanine racemase domain protein
A4G20_RS00040	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
A4G20_RS00050	ENOG4105CPW	cytochrome b561
A4G20_RS00060	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
A4G20_RS00085	ENOG4105C28	cystathionine
A4G20_RS00095	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A4G20_RS00100	ENOG4108J59	Extracellular solute-binding protein, family 5
A4G20_RS00110	ENOG4105RHG	
A4G20_RS00130	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A4G20_RS00145	ENOG4105C12	Phosphoribosylglycinamide synthetase
A4G20_RS00150	ENOG4105CD8	aminopeptidase N
A4G20_RS00155	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A4G20_RS00160	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A4G20_RS00165	ENOG4105W0Z	cytoplasmic protein
A4G20_RS00170	ENOG4107QP8	phosphohexose isomerase
A4G20_RS00175	ENOG41063M6	Cell Division Protein
A4G20_RS00180	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A4G20_RS00185	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A4G20_RS00190	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A4G20_RS00195	ENOG4105C6N	Formate acetyltransferase
A4G20_RS00200	ENOG4105TMB	Formate nitrite transporter
A4G20_RS00205	ENOG4105D98	threonine synthase
A4G20_RS00215	ENOG4105H4F	exported protein
A4G20_RS00220	ENOG4105EN6	Membrane
A4G20_RS00245	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
A4G20_RS00250	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
A4G20_RS00255	ENOG4105CEN	a g-specific adenine glycosylase
A4G20_RS00260	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
A4G20_RS00270	ENOG4105CFC	Transporter
A4G20_RS00275	ENOG4105CH2	amidohydrolase
A4G20_RS00285	ENOG4108XTF	Outer Membrane Lipoprotein
A4G20_RS00290	ENOG4105NBI	YecM protein
A4G20_RS00295	ENOG4105C75	arginyL-tRNA synthetase
A4G20_RS00300	ENOG4105C5A	transporter
A4G20_RS00305	ENOG4105E7W	lamb ycsf family protein
A4G20_RS00310	ENOG4107R7A	Allophanate hydrolase subunit 2
A4G20_RS00320	ENOG4105YES	addiction module antidote protein
A4G20_RS00330	ENOG4108JA2	transcriptioN-repair coupling factor
A4G20_RS00335	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A4G20_RS00340	ENOG4105DJ0	Poly(A) Polymerase
A4G20_RS00345	ENOG4105SVQ	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression (By similarity)
A4G20_RS00350	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
A4G20_RS00365	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
A4G20_RS00395	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
A4G20_RS00400	ENOG4108R3D	Electron transport complex
A4G20_RS00405	ENOG4105DGN	Electron transport complex
A4G20_RS00415	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A4G20_RS00465	ENOG4106AFN	Lyase and sodium transporter (By similarity)
A4G20_RS00470	ENOG4107QSA	Oxaloacetate decarboxylase
A4G20_RS00475	ENOG4105D9Q	decarboxylase (Beta subunit)
A4G20_RS00480	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A4G20_RS00490	ENOG4105CFC	Transporter
A4G20_RS00495	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A4G20_RS00500	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
A4G20_RS00505	ENOG4105CB5	ATP-dependent DNA helicase recG
A4G20_RS00510	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A4G20_RS00515	ENOG4105C79	DNA protecting protein DprA
A4G20_RS00525	ENOG4105EIF	outer membrane protein W
A4G20_RS00535	ENOG4107NA1	Endonuclease Exonuclease phosphatase
A4G20_RS00540	ENOG4105CK5	oxidoreductase
A4G20_RS00545	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A4G20_RS00565	ENOG41073TP	transcriptional regulator
A4G20_RS00585	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
A4G20_RS00590	ENOG4105DAN	ATP-dependent protease
A4G20_RS00595	ENOG4105DJ4	phosphatidylserine decarboxylase
A4G20_RS00605	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A4G20_RS00620	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
A4G20_RS00625	ENOG4108IJ1	Dehydrogenase
A4G20_RS00630	ENOG4105DZ2	Transcriptional regulator
A4G20_RS00635	ENOG4108WJ1	acetyltransferase
A4G20_RS00640	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A4G20_RS00645	ENOG4105CRQ	synthase (Component I)
A4G20_RS00660	ENOG4105D3Y	Na H antiporter
A4G20_RS00670	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
A4G20_RS00690	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A4G20_RS00700	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A4G20_RS00705	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A4G20_RS00710	ENOG4105C34	Pseudouridine synthase
A4G20_RS00720	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A4G20_RS00725	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
A4G20_RS00730	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A4G20_RS00755	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A4G20_RS00760	ENOG41083MP	50s ribosomal protein l29
A4G20_RS00765	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A4G20_RS00775	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A4G20_RS00780	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A4G20_RS00785	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A4G20_RS00790	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A4G20_RS00795	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A4G20_RS00815	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A4G20_RS00845	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A4G20_RS00855	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A4G20_RS00860	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
A4G20_RS00865	ENOG4105KZW	UPF0381 protein
A4G20_RS00870	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A4G20_RS00875	ENOG4105PM1	preprotein translocase subunit SecE
A4G20_RS00885	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
A4G20_RS00900	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A4G20_RS00905	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A4G20_RS00910	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A4G20_RS00915	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A4G20_RS00925	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A4G20_RS00930	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A4G20_RS00935	ENOG4105VPB	50S ribosomal protein L30
A4G20_RS00940	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A4G20_RS00945	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A4G20_RS00950	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A4G20_RS00955	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A4G20_RS00960	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A4G20_RS00980	ENOG4105C9Q	fumarate hydratase class II
A4G20_RS00985	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A4G20_RS00995	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A4G20_RS01000	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
A4G20_RS01015	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A4G20_RS01020	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A4G20_RS01025	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A4G20_RS01030	ENOG4105H1G	trap transporter solute receptor taxi family
A4G20_RS01060	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A4G20_RS01065	ENOG410863D	Flavinator of succinate dehydrogenase
A4G20_RS01070	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
A4G20_RS01075	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A4G20_RS01080	ENOG4108YZA	Nitrogen regulatory protein pii
A4G20_RS01090	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
A4G20_RS01100	ENOG4108UBT	opacity-associated protein
A4G20_RS01105	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
A4G20_RS01115	ENOG4105ECR	NmrA family
A4G20_RS01135	ENOG4105DEN	Luciferase family
A4G20_RS01140	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
A4G20_RS01150	ENOG4108Z33	Thiol disulfide Interchange Protein
A4G20_RS01165	ENOG4105H2K	paraquat-inducible protein a
A4G20_RS01205	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
A4G20_RS01210	ENOG4105DAD	Could be involved in ECA polysaccharide chain elongation (By similarity)
A4G20_RS01215	ENOG4105WPN	DNA integration recombination invertion protein
A4G20_RS01220	ENOG4105DZ1	carboxypeptidase
A4G20_RS01225	ENOG4105K6T	rare lipoprotein A
A4G20_RS01230	ENOG4105CNI	cell division protein FtsW
A4G20_RS01240	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
A4G20_RS01245	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
A4G20_RS01250	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A4G20_RS01265	ENOG4105CJP	fad dependent oxidoreductase
A4G20_RS01285	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
A4G20_RS01315	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A4G20_RS01335	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A4G20_RS01340	ENOG4108VZM	50s ribosomal protein L10
A4G20_RS01355	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A4G20_RS01365	ENOG4105C5Y	PTS System
A4G20_RS01400	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
A4G20_RS01405	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
A4G20_RS01410	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A4G20_RS01415	ENOG4105H1G	trap transporter solute receptor taxi family
A4G20_RS01430	ENOG4105CT1	(ABC) transporter
A4G20_RS01450	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A4G20_RS01455	ENOG4105EJ2	Transcriptional regulator
A4G20_RS01460	ENOG4105C5Q	Transcriptional regulator
A4G20_RS01465	ENOG4105EHV	domain protein
A4G20_RS01470	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A4G20_RS01475	ENOG41087AY	ADP-Ribose pyrophosphatase
A4G20_RS01480	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
A4G20_RS01510	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
A4G20_RS01515	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A4G20_RS01520	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A4G20_RS01530	ENOG4105ECY	inositol monophosphatase
A4G20_RS01535	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A4G20_RS01545	ENOG4108M1T	Cytochrome c-type biogenesis protein
A4G20_RS01550	ENOG4108M1T	Cytochrome c-type biogenesis protein
A4G20_RS01555	ENOG4107QX9	Thiol disulfide interChange protein
A4G20_RS01570	ENOG4106KVJ	cytochrome C assembly protein
A4G20_RS01580	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A4G20_RS01590	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
A4G20_RS01595	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A4G20_RS01600	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A4G20_RS01605	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A4G20_RS01610	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A4G20_RS01615	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A4G20_RS01620	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A4G20_RS01625	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A4G20_RS01640	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A4G20_RS01645	ENOG4108BGM	Quinol dehydrogenase periplasmic component
A4G20_RS01650	ENOG4105GXZ	Ferredoxin-type protein NapH
A4G20_RS01655	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
A4G20_RS01660	ENOG4105CUW	cytochrome C-TYPE protein
A4G20_RS01675	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A4G20_RS01715	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A4G20_RS01720	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
A4G20_RS01725	ENOG4108ETH	Formylglycinamide ribotide synthetase
A4G20_RS01735	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A4G20_RS01740	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A4G20_RS01745	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A4G20_RS01750	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A4G20_RS01755	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A4G20_RS01760	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
A4G20_RS01770	ENOG4105C8Y	Acetylornithine aminotransferase
A4G20_RS01780	ENOG4108XC3	NADH ubiquinone oxidoreductase
A4G20_RS01785	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A4G20_RS01815	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
A4G20_RS01820	ENOG4105NE1	Conserved Protein
A4G20_RS01825	ENOG41076KX	Protein of unknown function (DUF1469)
A4G20_RS01835	ENOG4108VIA	integral membrane protein
A4G20_RS01840	ENOG4105VZ9	UPF0235 protein
A4G20_RS01845	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
A4G20_RS01850	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A4G20_RS01860	ENOG4105C1A	potassium transporter peripheral membrane
A4G20_RS01870	ENOG4105K46	50S ribosomal protein l27
A4G20_RS01885	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A4G20_RS01890	ENOG410756H	nucleotidyltransferase
A4G20_RS01900	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
A4G20_RS01905	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
A4G20_RS01915	ENOG4106YJS	accessory processing protein
A4G20_RS01920	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
A4G20_RS01925	ENOG4107QSN	dihydrolipoamide acetyltransferase
A4G20_RS01930	ENOG4107QN2	dihydrolipoyl dehydrogenase
A4G20_RS01935	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A4G20_RS01940	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A4G20_RS01945	ENOG4105CXY	transporter
A4G20_RS01950	ENOG4108UHU	Aldolase
A4G20_RS01965	ENOG4105E9M	CRISPR-associated protein, Csn1 family
A4G20_RS01995	ENOG4108K3A	Glutathione S-transferase
A4G20_RS02000	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A4G20_RS02010	ENOG4105CDV	Ompa motb domain protein
A4G20_RS02020	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
A4G20_RS02025	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
A4G20_RS02030	ENOG4105WWK	YheO domain protein
A4G20_RS02035	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A4G20_RS02040	ENOG4105VRX	Protein slyX homolog
A4G20_RS02055	ENOG4105W0E	50S ribosomal protein L33
A4G20_RS02060	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
A4G20_RS02070	ENOG4105D0C	transport protein
A4G20_RS02075	ENOG4108IPT	Naphthoate synthase
A4G20_RS02085	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A4G20_RS02090	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
A4G20_RS02095	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A4G20_RS02145	ENOG41084CK	capsule polysaccharide
A4G20_RS02150	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A4G20_RS02155	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
A4G20_RS02160	ENOG4105F0N	pyrophosphate phospho-hydrolase
A4G20_RS02165	ENOG4105D0M	Protease HtpX homolog
A4G20_RS02170	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A4G20_RS02180	ENOG4105VCC	30S ribosomal protein S21
A4G20_RS02200	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A4G20_RS02210	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A4G20_RS02215	ENOG41063JG	Transcriptional regulator
A4G20_RS02220	ENOG4105C5I	Dehydrogenase
A4G20_RS02225	ENOG4105CFG	Acts as a chaperone (By similarity)
A4G20_RS02230	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A4G20_RS02245	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A4G20_RS02255	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
A4G20_RS02260	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A4G20_RS02270	ENOG4108R6K	riboflavin synthase, subunit alpha
A4G20_RS02275	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A4G20_RS02280	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A4G20_RS02285	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A4G20_RS02300	ENOG4108Z66	YbaK ebsC protein
A4G20_RS02305	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A4G20_RS02315	ENOG4105PE1	Receptor
A4G20_RS02320	ENOG4105C26	Dehydrogenase
A4G20_RS02325	ENOG4108BMY	protease
A4G20_RS02335	ENOG4105NXV	High-affinity zinc uptake system protein
A4G20_RS02340	ENOG4105D52	delta-aminolevulinic acid dehydratase
A4G20_RS02350	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A4G20_RS02355	ENOG4105EM7	Selenocysteine-specific translation elongation factor
A4G20_RS02360	ENOG4105E9S	glutaredoxin 2
A4G20_RS02365	ENOG4105DKW	ABC transporter
A4G20_RS02370	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
A4G20_RS02375	ENOG4105BZU	Histidine kinase
A4G20_RS02380	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A4G20_RS02385	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A4G20_RS02390	ENOG4105E2Z	phosphate ABC transporter (Permease
A4G20_RS02395	ENOG4105C8U	phosphate abc transporter
A4G20_RS02400	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
A4G20_RS02405	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
A4G20_RS02410	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A4G20_RS02415	ENOG4105HHA	aminodeoxychorismate lyase
A4G20_RS02450	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
A4G20_RS02455	ENOG4105XW2	UPF0263 protein
A4G20_RS02460	ENOG4107UWN	reductase
A4G20_RS02465	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A4G20_RS02475	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A4G20_RS02485	ENOG4105DJV	ribulose-phosphate 3-epimerase
A4G20_RS02490	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A4G20_RS02495	ENOG4105EZE	Cupin 4 family protein
A4G20_RS02500	ENOG4105VG0	50S ribosomal protein l34
A4G20_RS02505	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
A4G20_RS02510	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
A4G20_RS02515	ENOG4105CGK	Exodeoxyribonuclease III
A4G20_RS02525	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A4G20_RS02530	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
A4G20_RS02540	ENOG4105C6K	Malic enzyme
A4G20_RS02545	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A4G20_RS02555	ENOG4105CHR	reductase
A4G20_RS02560	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A4G20_RS02565	ENOG4105C59	p-type ATPase
A4G20_RS02570	ENOG4105UCG	Domain of unknown function (DUF333)
A4G20_RS02575	ENOG4105DFU	Cell wall formation (By similarity)
A4G20_RS02580	ENOG4107RUE	extracellular solute-binding protein family 1
A4G20_RS02585	ENOG4106HK8	GPR1 FUN34 yaaH family protein
A4G20_RS02590	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A4G20_RS02595	ENOG4105ETU	transcriptional activator (TenA
A4G20_RS02600	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
A4G20_RS02605	ENOG4105CSH	Transporter
A4G20_RS02615	ENOG4105C31	Tryptophanyl-tRNA synthetase
A4G20_RS02620	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A4G20_RS02630	ENOG4105QTB	Flavodoxin
A4G20_RS02640	ENOG4105W4M	Transport-associated protein
A4G20_RS02645	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A4G20_RS02650	ENOG41082RQ	UPF0102 protein
A4G20_RS02660	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A4G20_RS02665	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
A4G20_RS02670	ENOG4105CJR	Integral membrane protein (MviN
A4G20_RS02675	ENOG4108RR8	protoporphyrinogen oxidase
A4G20_RS02680	ENOG4105CVJ	phosphoglycerate mutase
A4G20_RS02685	ENOG4108W1A	pseudouridine synthase
A4G20_RS02690	ENOG4108JQ1	Dehydrogenase
A4G20_RS02695	ENOG4105E66	phosphoriboisomerase A
A4G20_RS02700	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A4G20_RS02715	ENOG4105DDQ	anthranilate synthase
A4G20_RS02720	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
A4G20_RS02725	ENOG4105D16	lipopolysaccharide heptosyltransferase i
A4G20_RS02730	ENOG410681U	heavy metal transport detoxification protein
A4G20_RS02740	ENOG4108KS2	transglutaminase domain protein
A4G20_RS02745	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
A4G20_RS02755	ENOG4105MJ2	Competence protein
A4G20_RS02760	ENOG4108X4Q	Hydrolase
A4G20_RS02770	ENOG4105I1J	Autotransporter
A4G20_RS02780	ENOG4107QPK	)-transporter
A4G20_RS02785	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A4G20_RS02790	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
A4G20_RS02800	ENOG4105RX8	Protein of unknown function (DUF1523)
A4G20_RS02805	ENOG4105F8V	Hydrolase, tatD family
A4G20_RS02810	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
A4G20_RS02815	ENOG4107T0K	Adenylate cyclase
A4G20_RS02820	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A4G20_RS02825	ENOG4105E0X	reductase
A4G20_RS02830	ENOG4105D9N	nucleoside
A4G20_RS02840	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
A4G20_RS02855	ENOG4105NF4	modulator of drug activity
A4G20_RS02865	ENOG4108I5U	Uridine phosphorylase
A4G20_RS02870	ENOG4108VVK	transcriptional Regulator, AsnC
A4G20_RS02875	ENOG4105CU9	asparagine synthetase A
A4G20_RS02890	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A4G20_RS02900	ENOG4108HWV	)-transporter
A4G20_RS02905	ENOG4105C2J	ABC transporter
A4G20_RS02910	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
A4G20_RS02920	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A4G20_RS02930	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A4G20_RS02940	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
A4G20_RS02955	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A4G20_RS02965	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
A4G20_RS02970	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
A4G20_RS02975	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
A4G20_RS02980	ENOG4105F1A	Pyruvate formate-lyase
A4G20_RS02985	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A4G20_RS02990	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
A4G20_RS02995	ENOG4105C2I	pirin domain protein
A4G20_RS03000	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
A4G20_RS03010	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A4G20_RS03015	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A4G20_RS03020	ENOG4108RH0	Crea protein
A4G20_RS03025	ENOG41090ED	Protein with unknown function (DUF469)
A4G20_RS03030	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A4G20_RS03055	ENOG4105CG5	Glycosyl transferase (Group 1
A4G20_RS03075	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
A4G20_RS03085	ENOG4108I4D	hemolysin
A4G20_RS03100	ENOG4105DSF	transport protein
A4G20_RS03110	ENOG4105DEF	Extracellular solute-binding protein, family 5
A4G20_RS03115	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
A4G20_RS03120	ENOG4105FS0	cytoplasmic membrane protein
A4G20_RS03125	ENOG4105D7K	pfkb domain protein
A4G20_RS03130	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
A4G20_RS03135	ENOG4105K5B	UPF0225 protein
A4G20_RS03140	ENOG4105C5F	glutamine synthetase
A4G20_RS03170	ENOG4108YZY	peptidylprolyl cis-trans isomerase
A4G20_RS03175	ENOG4105C7B	Threonine dehydratase
A4G20_RS03180	ENOG4105CFH	Aspartokinase
A4G20_RS03185	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
A4G20_RS03195	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
A4G20_RS03200	ENOG4105E98	transcriptional regulator DeoR family
A4G20_RS03205	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4G20_RS03220	ENOG4105DAS	pts system
A4G20_RS03225	ENOG4105ETZ	PTS System
A4G20_RS03230	ENOG4105F3R	pts system mannose fructose sorbose family iid
A4G20_RS03235	ENOG4108NK4	UPF0266 membrane protein
A4G20_RS03240	ENOG4105EIP	mannose-6-phosphate isomerase
A4G20_RS03245	ENOG4107RN3	metallophosphoesterase
A4G20_RS03250	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A4G20_RS03275	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A4G20_RS03280	ENOG41076HS	cation diffusion facilitator family transporter
A4G20_RS03290	ENOG4105D1Q	UPF0246 protein
A4G20_RS03295	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A4G20_RS03300	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
A4G20_RS03315	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A4G20_RS03320	ENOG4105VEJ	Heat shock protein
A4G20_RS03325	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A4G20_RS03345	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A4G20_RS03350	ENOG4105KNE	Phosphatidate cytidylyltransferase
A4G20_RS03355	ENOG4105DZP	Membrane-associated zinc metalloprotease
A4G20_RS03360	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A4G20_RS03370	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A4G20_RS03375	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
A4G20_RS03380	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A4G20_RS03390	ENOG4108VMM	UPF0756 membrane protein
A4G20_RS03395	ENOG4105CQ7	ATP-dependent helicase
A4G20_RS03400	ENOG41090BQ	Glutaredoxin
A4G20_RS03405	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
A4G20_RS03410	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A4G20_RS03415	ENOG4105E55	glycerol-3-phosphate acyltransferase
A4G20_RS03430	ENOG4108W2W	
A4G20_RS03435	ENOG4105CFP	Peptidase U32
A4G20_RS03465	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
A4G20_RS03480	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A4G20_RS03485	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
A4G20_RS03490	ENOG4105E33	succinate dehydrogenase
A4G20_RS03495	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
A4G20_RS03500	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
A4G20_RS03530	ENOG4107QTH	restriction modification system DNA specificity domain
A4G20_RS03535	ENOG4105KK6	nuclease
A4G20_RS03540	ENOG4105C9B	Cysteine desulfurase
A4G20_RS03545	ENOG4105CIN	aminoacyl-histidine dipeptidase
A4G20_RS03550	ENOG4108WZM	domain protein
A4G20_RS03555	ENOG4105DC8	reductase
A4G20_RS03565	ENOG4105CUW	cytochrome C-TYPE protein
A4G20_RS03570	ENOG4107QY8	reductase
A4G20_RS03580	ENOG4108WFC	UPF0438 protein yifE
A4G20_RS03585	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
A4G20_RS03595	ENOG4105WBN	Transcriptional regulator (LacI family
A4G20_RS03605	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
A4G20_RS03610	ENOG4105C09	Bile acid
A4G20_RS03615	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
A4G20_RS03620	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
A4G20_RS03625	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A4G20_RS03630	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A4G20_RS03655	ENOG4108IQE	Amp-dependent synthetase and ligase
A4G20_RS03680	ENOG410890F	Dynamin family
A4G20_RS03685	ENOG4105R3P	Inner membrane protein yagU
A4G20_RS03695	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A4G20_RS03700	ENOG4108I6E	Sulfatase
A4G20_RS03705	ENOG4105C2X	Arabinose 5-phosphate isomerase
A4G20_RS03715	ENOG4105C4R	Atp-dependent dna helicase
A4G20_RS03720	ENOG4105CXG	d-lactate dehydrogenase
A4G20_RS03725	ENOG4107QYX	exodeoxyribonuclease v alpha
A4G20_RS03730	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
A4G20_RS03735	ENOG4108MN8	Membrane
A4G20_RS03740	ENOG4105X3C	heme exporter protein
A4G20_RS03745	ENOG41060IM	Heme exporter protein
A4G20_RS03750	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
A4G20_RS03755	ENOG4105D9R	oxidoreductase
A4G20_RS03760	ENOG4107QI1	Mate efflux family protein
A4G20_RS03770	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
A4G20_RS03780	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A4G20_RS03790	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A4G20_RS03795	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A4G20_RS03815	ENOG4105CJ2	(LipO)protein
A4G20_RS03825	ENOG4105M6F	mutator MutT protein
A4G20_RS03830	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
A4G20_RS03835	ENOG4105K8N	protein family UPF0079, ATPase
A4G20_RS03840	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A4G20_RS03845	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
A4G20_RS03850	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
A4G20_RS03855	ENOG4108IUZ	ABC transporter
A4G20_RS03860	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
A4G20_RS03865	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
A4G20_RS03870	ENOG4105DEF	Extracellular solute-binding protein, family 5
A4G20_RS03880	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4G20_RS03885	ENOG4105C3U	ABC transporter
A4G20_RS03890	ENOG4108JQ7	(ABC) transporter
A4G20_RS03895	ENOG4105C5Y	PTS System
A4G20_RS03900	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
A4G20_RS03905	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
A4G20_RS03910	ENOG4105IEY	(LipO)protein
A4G20_RS03915	ENOG4105M85	Bola protein
A4G20_RS03935	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
A4G20_RS03940	ENOG4105E0U	tyrosine-specific transport protein
A4G20_RS03945	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A4G20_RS03950	ENOG4105CNI	cell division protein FtsW
A4G20_RS03955	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
A4G20_RS03960	ENOG4108J59	Extracellular solute-binding protein, family 5
A4G20_RS03965	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A4G20_RS03970	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A4G20_RS03975	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
A4G20_RS03985	ENOG41082NX	50s ribosomal protein l35
A4G20_RS03990	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A4G20_RS03995	ENOG4108BY2	phosphohistidine phosphatase
A4G20_RS04000	ENOG4105CA9	Pyruvate kinase
A4G20_RS04005	ENOG4105DKP	glycosyl transferase, family 9
A4G20_RS04010	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A4G20_RS04015	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
A4G20_RS04025	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
A4G20_RS04030	ENOG4107RNH	Outer membrane receptor FepA
A4G20_RS04035	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
A4G20_RS04045	ENOG4105D2S	major facilitator superfamily
A4G20_RS04050	ENOG4105VSH	4-oxalocrotonate tautomerase
A4G20_RS04060	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
A4G20_RS04080	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A4G20_RS04095	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A4G20_RS04100	ENOG4105DQ6	Transposase
A4G20_RS04115	ENOG4105CQ0	ABC transporter
A4G20_RS04150	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A4G20_RS04155	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
A4G20_RS04165	ENOG4105CH7	arginosuccinase
A4G20_RS04170	ENOG4108JQ5	ABC transporter
A4G20_RS04175	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4G20_RS04180	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A4G20_RS04185	ENOG4108J59	Extracellular solute-binding protein, family 5
A4G20_RS04190	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A4G20_RS04195	ENOG4105E0M	Sulfatase
A4G20_RS04200	ENOG4106K28	UPF0283 membrane protein
A4G20_RS04205	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A4G20_RS04210	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A4G20_RS04215	ENOG4105CJN	penicillin-binding protein
A4G20_RS04225	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A4G20_RS04230	ENOG4105MYG	DNA polymerase iii, chi subunit
A4G20_RS04275	ENOG4105CUC	YeeE YedE family protein
A4G20_RS04285	ENOG4105C7N	Xanthine uracil vitamin C permease
A4G20_RS04300	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
A4G20_RS04315	ENOG4108MVK	Receptor
A4G20_RS04325	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
A4G20_RS04335	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A4G20_RS04340	ENOG4105CNT	hydrolase family 2
A4G20_RS04350	ENOG4105C8P	)-transporter
A4G20_RS04365	ENOG4105D38	putrescine abc transporter
A4G20_RS04370	ENOG4105F38	ABC transporter, permease
A4G20_RS04375	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A4G20_RS04390	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
A4G20_RS04395	ENOG4108UYE	Lactoylglutathione lyase
A4G20_RS04420	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A4G20_RS04430	ENOG4107H52	Dicarboxylate transport
A4G20_RS04435	ENOG410689M	(LipO)protein
A4G20_RS04440	ENOG4105DEF	Extracellular solute-binding protein, family 5
A4G20_RS04445	ENOG4105C3G	gtp-binding protein
A4G20_RS04450	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A4G20_RS04455	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4G20_RS04460	ENOG4105CE9	30S ribosomal protein S2
A4G20_RS04465	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A4G20_RS04470	ENOG4105CHH	sulfate transporter
A4G20_RS04480	ENOG4105E0K	tonB-dependent siderophore receptor
A4G20_RS04485	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
A4G20_RS04495	ENOG4105E0A	ABC, transporter
A4G20_RS04505	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A4G20_RS04510	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
A4G20_RS04515	ENOG4105C0H	protease
A4G20_RS04520	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A4G20_RS04545	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A4G20_RS04550	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A4G20_RS04555	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A4G20_RS04560	ENOG4107QKA	exodeoxyribonuclease V beta
A4G20_RS04565	ENOG4107QKA	exodeoxyribonuclease V beta
A4G20_RS04570	ENOG4105CRQ	synthase (Component I)
A4G20_RS04575	ENOG4105DDQ	anthranilate synthase
A4G20_RS04595	ENOG4108RXX	maleylacetoacetate isomerase
A4G20_RS04600	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A4G20_RS04605	ENOG4108RCM	Nitroreductase
A4G20_RS04610	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
A4G20_RS04620	ENOG4107QX8	SPFH domain, Band 7 family protein
A4G20_RS04625	ENOG4105EYA	deoxyribonuclease
A4G20_RS04630	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
A4G20_RS04635	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A4G20_RS04640	ENOG4106H78	methyltransferase
A4G20_RS04645	ENOG4108RYC	glycosyltransferase
A4G20_RS04650	ENOG4108RJ9	Glycosyl transferase, family 2
A4G20_RS04665	ENOG41068D6	Glycosyltransferase
A4G20_RS04670	ENOG4105P7J	Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D- glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide
A4G20_RS04675	ENOG4108MY6	biosynthesis protein
A4G20_RS04685	ENOG41080C8	DUF218 domain
A4G20_RS04690	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A4G20_RS04695	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
A4G20_RS04705	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A4G20_RS04710	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A4G20_RS04715	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A4G20_RS04720	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A4G20_RS04725	ENOG4108M8S	permease YjgP YjgQ family protein
A4G20_RS04730	ENOG4108K5H	permease YjgP YjgQ family protein
A4G20_RS04735	ENOG41061WM	D-Alanyl-D-Alanine
A4G20_RS04745	ENOG4105F7F	Chaperone
A4G20_RS04765	ENOG4105D7T	ABC transporter
A4G20_RS04780	ENOG4105CEP	NADH dehydrogenase
A4G20_RS04795	ENOG4108IYH	Dna topoisomerase
A4G20_RS04800	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
A4G20_RS04805	ENOG41090JE	Utilization Protein
A4G20_RS04810	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
A4G20_RS04850	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
A4G20_RS04855	ENOG4108IJ0	Aspartate ammonia-lyase
A4G20_RS04875	ENOG4105C0H	protease
A4G20_RS04910	ENOG4105CRK	lysyL-tRNA synthetase
A4G20_RS04925	ENOG410650H	(LipO)protein
A4G20_RS04930	ENOG4105DBE	peroxidase
A4G20_RS04935	ENOG4107SJW	iron permease, FTR1
A4G20_RS04945	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A4G20_RS04950	ENOG4105C7N	Xanthine uracil vitamin C permease
A4G20_RS04955	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A4G20_RS04960	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
A4G20_RS04965	ENOG4108DG9	Smr protein MutS2
A4G20_RS04970	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
A4G20_RS04975	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A4G20_RS04980	ENOG4105EUU	Sel1 domain protein repeat-containing protein
A4G20_RS04990	ENOG4105C0H	protease
A4G20_RS05000	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A4G20_RS05030	ENOG4105ENX	hydrolase
A4G20_RS05035	ENOG4105W8I	Transcriptional regulator
A4G20_RS05040	ENOG4108KTG	Membrane protein, drug metabolite transporter
A4G20_RS05045	ENOG4108ZT1	Transcriptional regulator
A4G20_RS05060	ENOG4105UNS	Pfam:DUF419
A4G20_RS05075	ENOG4105RV9	Transcriptional regulator
A4G20_RS05085	ENOG4105ECQ	AraC Family Transcriptional Regulator
A4G20_RS05090	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
A4G20_RS05110	ENOG4105G6Z	alkaline phosphatase
A4G20_RS05120	ENOG4107R11	Transcriptional regulator
A4G20_RS05125	ENOG4105DDY	UPF0142 protein ycaO
A4G20_RS05130	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A4G20_RS05135	ENOG4105DSJ	YicC domain protein
A4G20_RS05140	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
A4G20_RS05145	ENOG4105PAD	Hydrolase
A4G20_RS05160	ENOG4105C03	ribonuclease
A4G20_RS05180	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A4G20_RS05200	ENOG4106N3A	copper homeostasis protein cutc
A4G20_RS05210	ENOG4105DB7	PHP domain protein
A4G20_RS05220	ENOG4105VNG	YcgL domain-containing protein
A4G20_RS05225	ENOG4105CDU	Replicative dna helicase
A4G20_RS05230	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
A4G20_RS05235	ENOG4105D4P	Coproporphyrinogen iii oxidase
A4G20_RS05240	ENOG4105XCT	Protein of unknown function (DUF2489)
A4G20_RS05245	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
A4G20_RS05295	ENOG4105WAB	arsR family transcriptional regulator
A4G20_RS05310	ENOG4105EIG	urea carboxylase-associated protein 1
A4G20_RS05320	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
A4G20_RS05330	ENOG4105DVT	helicase
A4G20_RS05335	ENOG4105VAW	lrga family
A4G20_RS05340	ENOG41067MG	lrgb family
A4G20_RS05345	ENOG4105BZ1	(ABC) transporter
A4G20_RS05350	ENOG4107QNR	UPF0135 protein
A4G20_RS05355	ENOG4105DBI	uridine monophosphokinase
A4G20_RS05360	ENOG4105DHP	deoxycytidine triphosphate deaminase
A4G20_RS05365	ENOG4107QX9	Thiol disulfide interChange protein
A4G20_RS05370	ENOG4108DMF	Cytochrome C biogenesis protein
A4G20_RS05385	ENOG4108R96	Methyltransferase, YaeB family
A4G20_RS05390	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
A4G20_RS05395	ENOG4107QWE	)-transporter
A4G20_RS05400	ENOG4105D6U	Sodium Glutamate Symporter
A4G20_RS05405	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A4G20_RS05410	ENOG4105DHQ	Histidine kinase
A4G20_RS05415	ENOG4105C6T	cysteine synthase
A4G20_RS05420	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
A4G20_RS05425	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
A4G20_RS05430	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A4G20_RS05435	ENOG4105C7S	Dehydrogenase
A4G20_RS05445	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A4G20_RS05450	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
A4G20_RS05455	ENOG4105EV9	Alpha Beta Hydrolase
A4G20_RS05460	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
A4G20_RS05465	ENOG4105CEY	Amp-dependent synthetase and ligase
A4G20_RS05475	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
A4G20_RS05480	ENOG4105EGS	Mechanosensitive ion channel
A4G20_RS05485	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
A4G20_RS05495	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
A4G20_RS05505	ENOG4105E0X	reductase
A4G20_RS05510	ENOG4105D7X	high-affinity nickel-transporter
A4G20_RS05515	ENOG41065CD	Exported protein
A4G20_RS05525	ENOG4105ETT	transcriptional Regulator, LysR family
A4G20_RS05530	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A4G20_RS05535	ENOG4105M4H	endoribonuclease L-psp
A4G20_RS05540	ENOG4105CGH	5'-nucleotidase
A4G20_RS05545	ENOG41080IJ	Diacylglycerol kinase
A4G20_RS05550	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
A4G20_RS05555	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A4G20_RS05590	ENOG4105R8V	Transcriptional regulator
A4G20_RS05595	ENOG4106YXT	transposase
A4G20_RS05605	ENOG4108WTW	DNA transposition protein
A4G20_RS05615	ENOG4105IKI	host-nuclease inhibitor protein
A4G20_RS05635	ENOG4105ZIA	Phage protein gp16
A4G20_RS05640	ENOG41065S5	
A4G20_RS05690	ENOG4108Z6H	mu-like prophage Flumu protein gp27
A4G20_RS05710	ENOG4107XYH	virion morphogenesis protein
A4G20_RS05820	ENOG4107H6E	
A4G20_RS05830	ENOG4108R0G	Tetratricopeptide repeat protein
A4G20_RS05840	ENOG4107RUE	extracellular solute-binding protein family 1
A4G20_RS05845	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
A4G20_RS05850	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
A4G20_RS05855	ENOG4105D6S	protein involved in catabolism of external DNA
A4G20_RS05860	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A4G20_RS05870	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A4G20_RS05875	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
A4G20_RS05880	ENOG4105D0A	hydroxylase
A4G20_RS05885	ENOG4105EI2	Pseudouridine synthase
A4G20_RS05890	ENOG4107QSI	ABC, transporter
A4G20_RS05905	ENOG4108JQ7	(ABC) transporter
A4G20_RS05915	ENOG4105E68	Sulfatase
A4G20_RS05920	ENOG4105PAN	UPF0352 protein
A4G20_RS05940	ENOG4105K4U	addiction module toxin, RelE StbE family
A4G20_RS05955	ENOG4105VFB	Binds the 23S rRNA (By similarity)
A4G20_RS05960	ENOG4105EMY	transcriptional regulator
A4G20_RS05975	ENOG4105C5S	asparaginyl-tRNA synthetase
A4G20_RS05980	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A4G20_RS05985	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
A4G20_RS05995	ENOG4108ZZ3	UPF0260 protein
A4G20_RS06000	ENOG4105K8R	UPF0145 protein
A4G20_RS06005	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A4G20_RS06020	ENOG4107R6U	sodium dicarboxylate symporter
A4G20_RS06030	ENOG4105CSM	endonuclease III
A4G20_RS06035	ENOG4105EJ9	Membrane
A4G20_RS06040	ENOG4108J59	Extracellular solute-binding protein, family 5
A4G20_RS06050	ENOG4105EMN	RNA polymerase sigma factor
A4G20_RS06055	ENOG41069PW	sigma-e factor negative regulatory protein
A4G20_RS06070	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
A4G20_RS06075	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A4G20_RS06080	ENOG4105DFF	Rod shape-determining protein mreb
A4G20_RS06085	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
A4G20_RS06095	ENOG4105D1H	recombination factor protein RarA
A4G20_RS06100	ENOG4108RE7	deoxyribonuclease
A4G20_RS06105	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A4G20_RS06160	ENOG4105CH6	catalase
A4G20_RS06165	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
A4G20_RS06170	ENOG4105VTW	prevent-host-death family
A4G20_RS06190	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A4G20_RS06200	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
A4G20_RS06205	ENOG4108WPU	DNA polymerase III subunit psi
A4G20_RS06215	ENOG4105CK7	Sodium proline symporter
A4G20_RS06225	ENOG4108P11	EamA-like transporter family
A4G20_RS06235	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A4G20_RS06240	ENOG4105CFH	Aspartokinase
A4G20_RS06250	ENOG4105VEQ	Cold shock protein
A4G20_RS06260	ENOG4108RMU	ferritin dps family protein
A4G20_RS06265	ENOG4105EJQ	L-serine dehydratase
A4G20_RS06270	ENOG4105CAF	HipA N-terminal domain protein
A4G20_RS06280	ENOG4105C8N	cysteinyl-tRNA synthetase
A4G20_RS06290	ENOG4108HMX	isocitrate dehydrogenase (NADP)
A4G20_RS06295	ENOG4105E0U	tyrosine-specific transport protein
A4G20_RS06300	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
A4G20_RS06305	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
A4G20_RS06310	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A4G20_RS06315	ENOG4105CC5	ABC transporter
A4G20_RS06320	ENOG4105CC5	ABC transporter
A4G20_RS06325	ENOG4105DIK	(ABC) transporter
A4G20_RS06345	ENOG4105C0H	protease
A4G20_RS06350	ENOG4105CAT	Cytidine monophosphate kinase
A4G20_RS06355	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A4G20_RS06360	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A4G20_RS06365	ENOG4105Q4A	inner membrane protein yciS
A4G20_RS06370	ENOG4105CFV	Tetratricopeptide repeat protein
A4G20_RS06375	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A4G20_RS06380	ENOG4108ZJT	translation initiation factor, Sui1
A4G20_RS06385	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A4G20_RS06390	ENOG4107SC1	transglycosylase
A4G20_RS06395	ENOG4105EW9	transcriptional regulator AsnC family
A4G20_RS06400	ENOG4105C0D	helicase
A4G20_RS06410	ENOG4107QMH	DNA methylase
A4G20_RS06415	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A4G20_RS06420	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A4G20_RS06430	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
A4G20_RS06440	ENOG4105CJ3	phosphate transporter
A4G20_RS06445	ENOG4107IX6	phosphate transport regulator
A4G20_RS06450	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A4G20_RS06460	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A4G20_RS06465	ENOG4108QBX	(LipO)protein
A4G20_RS06470	ENOG4105VQK	sigma E regulatory protein, MucB RseB
A4G20_RS06480	ENOG4107MKT	Stringent starvation protein a
A4G20_RS06485	ENOG4105KB2	stringent starvation protein b
A4G20_RS06490	ENOG4106CC8	Bacterial inner membrane protein
A4G20_RS06495	ENOG4105CEY	Amp-dependent synthetase and ligase
A4G20_RS06500	ENOG4105BZN	citrate synthase
A4G20_RS06505	ENOG4107QIJ	Aconitate hydratase 2
A4G20_RS06510	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
A4G20_RS06515	ENOG4105CGF	Aromatic amino acid aminotransferase
A4G20_RS06520	ENOG4105CIY	formyltetrahydrofolate deformylase
A4G20_RS06525	ENOG4108X73	DNA- binding protein
A4G20_RS06530	ENOG4107S6Z	Na H antiporter
A4G20_RS06535	ENOG4105CNU	cell division protein FtsK
A4G20_RS06545	ENOG4105DFS	Conserved Protein
A4G20_RS06565	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
A4G20_RS06570	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
A4G20_RS06580	ENOG4108WQI	RNA Polymerase
A4G20_RS06590	ENOG4105VFE	sira family
A4G20_RS06595	ENOG4105M08	Membrane
A4G20_RS06610	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
A4G20_RS06615	ENOG4105CHV	Transcription elongation factor NusA
A4G20_RS06625	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A4G20_RS06630	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
A4G20_RS06635	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
A4G20_RS06640	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A4G20_RS06645	ENOG4105C1J	atp-dependent rna helicase
A4G20_RS06655	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
A4G20_RS06660	ENOG4105EMU	Dehydrogenase
A4G20_RS06665	ENOG4105CHU	acetyl-coa acetyltransferase
A4G20_RS06670	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A4G20_RS06675	ENOG4105CKW	Inner membrane protein yedI
A4G20_RS06680	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
A4G20_RS06695	ENOG4105CSA	Coproporphyrinogen iii oxidase
A4G20_RS06705	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A4G20_RS06710	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
A4G20_RS06715	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A4G20_RS06720	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A4G20_RS06730	ENOG4105CHF	Glutathione S-transferase
A4G20_RS06740	ENOG4108ZT1	Transcriptional regulator
A4G20_RS06755	ENOG4105CGZ	zinc metallopeptidase
A4G20_RS06760	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
A4G20_RS06765	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
A4G20_RS06770	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
A4G20_RS06775	ENOG4108Z6B	deaminase
A4G20_RS06780	ENOG4105DZR	Type I site-specific deoxyribonuclease
A4G20_RS06805	ENOG4105EKX	Restriction modification system DNA (Specificity
A4G20_RS06810	ENOG4105CVR	type I restriction-modification system
A4G20_RS06815	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A4G20_RS06820	ENOG4105KWI	UPF0339 protein
A4G20_RS06840	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A4G20_RS06845	ENOG4105QEK	Transcriptional regulator
A4G20_RS06850	ENOG4108R66	Conserved Protein
A4G20_RS06855	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
A4G20_RS06860	ENOG4105N42	UPF0307 protein
A4G20_RS06870	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A4G20_RS06875	ENOG4105HDK	L-asparaginase
A4G20_RS06880	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A4G20_RS06885	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
A4G20_RS06895	ENOG4105DGW	oligopeptidase A
A4G20_RS06900	ENOG4105CEE	C4-dicarboxylate transporter
A4G20_RS06935	ENOG4105CJB	Exodeoxyribonuclease I
A4G20_RS06940	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
A4G20_RS06945	ENOG4105C9X	ppx gppa phosphatase
A4G20_RS06950	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A4G20_RS06955	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
A4G20_RS06960	ENOG4105NSG	hemerythrin hhe cation binding domain protein
A4G20_RS06990	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A4G20_RS06995	ENOG4105ERU	peptidase
A4G20_RS07000	ENOG4108JJB	ABC transporter
A4G20_RS07035	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A4G20_RS07040	ENOG4105CC0	LysR family Transcriptional regulator
A4G20_RS07060	ENOG4105C2M	dna polymerase I
A4G20_RS07065	ENOG4108TZV	Membrane
A4G20_RS07070	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
A4G20_RS07080	ENOG4105E0C	molybdate abc transporter
A4G20_RS07085	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
A4G20_RS07090	ENOG4105F4R	Transcriptional regulator mode
A4G20_RS07105	ENOG4105D01	(LipO)protein
A4G20_RS07110	ENOG4105D01	(LipO)protein
A4G20_RS07115	ENOG4105D01	(LipO)protein
A4G20_RS07120	ENOG4108UMI	ABC transporter, permease
A4G20_RS07125	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A4G20_RS07130	ENOG41090EX	DsrE family
A4G20_RS07135	ENOG4105DWV	Homoserine O-trans-acetylase
A4G20_RS07140	ENOG4108SXK	Transporter Drug Metabolite Exporter family
A4G20_RS07145	ENOG4107GZ4	SanA protein
A4G20_RS07150	ENOG4105CA3	membrane-bound lytic murein transglycosylase
A4G20_RS07160	ENOG41090HJ	UPF0265 protein
A4G20_RS07165	ENOG4108ZAF	Molybdopterin
A4G20_RS07170	ENOG4105M00	molybdopterin converting factor, subunit 1
A4G20_RS07175	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A4G20_RS07195	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A4G20_RS07205	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
A4G20_RS07215	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
A4G20_RS07220	ENOG4108MG3	formate dehydrogenase
A4G20_RS07225	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A4G20_RS07245	ENOG4107RAQ	aminopeptidase
A4G20_RS07250	ENOG4105DXN	mazG family
A4G20_RS07255	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A4G20_RS07260	ENOG4105E0F	Histidine kinase
A4G20_RS07265	ENOG41077A9	carbonic anhydrase
A4G20_RS07270	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
A4G20_RS07275	ENOG4107ZVW	dihydroneopterin aldolase
A4G20_RS07280	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
A4G20_RS07295	ENOG4105BZS	acriflavin resistance protein
A4G20_RS07300	ENOG410624X	efflux transporter, rnd family, mfp subunit
A4G20_RS07305	ENOG4105Y7M	Transcriptional regulator, TetR family
A4G20_RS07310	ENOG4105EIN	peptidylprolyl cis-trans isomerase
A4G20_RS07325	ENOG4105EEQ	Na H antiporter
A4G20_RS07335	ENOG4108V0P	LemA family
A4G20_RS07350	ENOG4105X5C	UPF0181 protein
A4G20_RS07365	ENOG4105C4Y	ABC transporter
A4G20_RS07380	ENOG4105CFU	surface antigen
A4G20_RS07385	ENOG4105MA0	exported protein
A4G20_RS07390	ENOG4108JJ9	ABC, transporter
A4G20_RS07395	ENOG4105CVE	Lytic murein transglycosylase
A4G20_RS07400	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A4G20_RS07405	ENOG4108DBC	nitroreductase
A4G20_RS07410	ENOG4105CBT	Fructose-1,6-bisphosphatase
A4G20_RS07425	ENOG4107104	thymidine kinase
A4G20_RS07450	ENOG4108JJ8	(ABC) transporter
A4G20_RS07455	ENOG4105F27	Major Facilitator
A4G20_RS07460	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A4G20_RS07465	ENOG41063SB	peptidase
A4G20_RS07470	ENOG4105PXI	polysaccharide deacetylase
A4G20_RS07490	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A4G20_RS07500	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
A4G20_RS07505	ENOG4105C28	cystathionine
A4G20_RS07510	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
A4G20_RS07525	ENOG41072GX	Peptidase M22 Glycoprotease
A4G20_RS07530	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A4G20_RS07535	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4G20_RS07540	ENOG4105K59	histidine triad (HIT) protein
A4G20_RS07555	ENOG4105E1F	short-chain dehydrogenase reductase
A4G20_RS07560	ENOG41069NU	Nitroreductase
A4G20_RS07565	ENOG4105D07	Signal peptide peptidase, SppA
A4G20_RS07580	ENOG4107QTF	adenylosuccinate lyase
A4G20_RS07585	ENOG41075W9	High frequency lysogenization protein HflD homolog
A4G20_RS07615	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A4G20_RS07620	ENOG4106V8H	Nucleoid-associated protein
A4G20_RS07625	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A4G20_RS07630	ENOG4107QMP	dna polymerase iii subunits gamma and tau
A4G20_RS07635	ENOG4105DA5	(ABC) transporter
A4G20_RS07640	ENOG4105E3A	(ABC) transporter
A4G20_RS07645	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
A4G20_RS07665	ENOG4105DP9	ABC transporter
A4G20_RS07680	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A4G20_RS07690	ENOG4105DBV	ornithine carbamoyltransferase
A4G20_RS07705	ENOG4105C1J	atp-dependent rna helicase
A4G20_RS07715	ENOG4105WVQ	Fe-S assembly protein IscX
A4G20_RS07720	ENOG4108ZIT	Ferredoxin, 2FE-2S
A4G20_RS07745	ENOG4108RF1	Protein of unknown function DUF2625
A4G20_RS07760	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
A4G20_RS07765	ENOG4108Z4V	iron-sulfur cluster assembly
A4G20_RS07770	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
A4G20_RS07775	ENOG4105C3J	Cysteine desulfurase
A4G20_RS07780	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
A4G20_RS07785	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A4G20_RS07790	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
A4G20_RS07800	ENOG4105DM4	PTS System
A4G20_RS07805	ENOG4105DE4	1-phosphofructokinase
A4G20_RS07810	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
A4G20_RS07820	ENOG4108ESZ	Glycogen debranching enzyme
A4G20_RS07825	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A4G20_RS07830	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A4G20_RS07835	ENOG4108JQ5	ABC transporter
A4G20_RS07840	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4G20_RS07845	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A4G20_RS07850	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
A4G20_RS07855	ENOG4105C8Y	Acetylornithine aminotransferase
A4G20_RS07860	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
A4G20_RS07865	ENOG4105D1S	lipid A biosynthesis
A4G20_RS07870	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
A4G20_RS07875	ENOG4105EYK	Phosphatidylglycerophosphatase B
A4G20_RS07880	ENOG4105HBR	Rna-binding protein
A4G20_RS07895	ENOG4108DNC	Involved in acetate metabolism (By similarity)
A4G20_RS07905	ENOG4105I7R	Adenylate cyclase
A4G20_RS07910	ENOG4105CM6	amino acid regulated cytosolic protein
A4G20_RS07920	ENOG4108IPW	abc transporter atp-binding protein
A4G20_RS07925	ENOG4105CM4	permease protein
A4G20_RS07930	ENOG4105DHS	permease protein
A4G20_RS07940	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4G20_RS07970	ENOG4105SYT	Methylenetetrahydrofolate reductase
A4G20_RS07975	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
A4G20_RS07980	ENOG4105UGU	tonB-dependent Receptor
A4G20_RS07985	ENOG4105C9A	Phoh family
A4G20_RS07990	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A4G20_RS07995	ENOG4105D0M	Protease HtpX homolog
A4G20_RS08000	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
A4G20_RS08015	ENOG4105DWU	Membrane
A4G20_RS08020	ENOG4105CE4	GlcNAc 6-P deacetylase
A4G20_RS08025	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
A4G20_RS08030	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A4G20_RS08035	ENOG4105DA4	cytochrome c-type biogenesis protein
A4G20_RS08040	ENOG4105DVI	reductase, NrfD
A4G20_RS08045	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A4G20_RS08050	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
A4G20_RS08055	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
A4G20_RS08065	ENOG4105EQ2	LysR family Transcriptional regulator
A4G20_RS08070	ENOG4105CV8	reductase
A4G20_RS08075	ENOG4105CPC	Aldo Keto reductase
A4G20_RS08080	ENOG4108ZP8	Acetolactate synthase small subunit
A4G20_RS08085	ENOG4105C7K	acetolactate synthase
A4G20_RS08095	ENOG4105CDY	transcriptional regulatory protein
A4G20_RS08100	ENOG4108TIT	dATP pyrophosphohydrolase
A4G20_RS08155	ENOG4105II7	pyrroline-5-carboxylate reductase
A4G20_RS08160	ENOG4105D8G	Major Facilitator superfamily
A4G20_RS08180	ENOG4105FE9	pseudouridine synthase
A4G20_RS08185	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
A4G20_RS08190	ENOG4105BZM	domain protein
A4G20_RS08205	ENOG4105DVA	methyltransferase
A4G20_RS08220	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A4G20_RS08225	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A4G20_RS08235	ENOG4105M15	transport protein ExbD
A4G20_RS08240	ENOG4105M8K	biopolymer transport protein
A4G20_RS08250	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
A4G20_RS08255	ENOG4105CTQ	phosphohexokinase
A4G20_RS08260	ENOG4108VTV	Inherit from NOG: Membrane
A4G20_RS08265	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
A4G20_RS08270	ENOG4108JU8	Transcriptional regulator
A4G20_RS08275	ENOG4108EVY	peptide transport periplasmic protein
A4G20_RS08285	ENOG4108EU3	peptide transport system, permease
A4G20_RS08290	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
A4G20_RS08295	ENOG4105C2W	permease
A4G20_RS08300	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A4G20_RS08305	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A4G20_RS08315	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
A4G20_RS08335	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
A4G20_RS08340	ENOG4105CQC	Prephenate dehydratase
A4G20_RS08350	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A4G20_RS08355	ENOG4105BZG	amino acid carrier protein
A4G20_RS08370	ENOG4105CUZ	uba thif-type nad fad binding protein
A4G20_RS08380	ENOG4105C37	(CBS) domain
A4G20_RS08385	ENOG4105D60	lipoprotein releasing system transmembrane protein
A4G20_RS08390	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A4G20_RS08395	ENOG410836F	Transposase
A4G20_RS08405	ENOG4105C5H	ABC transporter
A4G20_RS08420	ENOG4108RRZ	Transcription elongation factor GreB
A4G20_RS08430	ENOG4105D7W	serine acetyltransferase
A4G20_RS08435	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A4G20_RS08440	ENOG4108IYU	L-aspartate oxidase
A4G20_RS08445	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A4G20_RS08450	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
A4G20_RS08455	ENOG4105VEQ	Cold shock protein
A4G20_RS08460	ENOG4105D7A	ATP-binding protein
A4G20_RS08465	ENOG4105W49	UPF0434 protein
A4G20_RS08470	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
A4G20_RS08475	ENOG4105MZU	cell filamentation protein
A4G20_RS08485	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A4G20_RS08490	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A4G20_RS08500	ENOG4108ZF3	Phosphatase
A4G20_RS08515	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A4G20_RS08540	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A4G20_RS08550	ENOG4105RG0	Membrane
A4G20_RS08555	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
A4G20_RS08560	ENOG410903C	(LipO)protein
A4G20_RS08565	ENOG4105DSB	aldose 1-epimerase
A4G20_RS08570	ENOG4105BZW	Glycerate kinase
A4G20_RS08575	ENOG4105C6Z	Gluconate
A4G20_RS08580	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A4G20_RS08585	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A4G20_RS08595	ENOG4108VPT	UPF0234 protein
A4G20_RS08600	ENOG4105EAC	phosphoserine phosphatase
A4G20_RS08605	ENOG41062Z9	Membrane
A4G20_RS08610	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A4G20_RS08615	ENOG4105VDB	UPF0125 protein
A4G20_RS08620	ENOG4108Z1B	Cyclase dehydrase
A4G20_RS08625	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A4G20_RS08630	ENOG4105KME	endoribonuclease L-psp
A4G20_RS08635	ENOG4105E7A	Glutamine amidotransferase
A4G20_RS08640	ENOG4105FAV	ABC, transporter
A4G20_RS08645	ENOG4105FDK	ABC transporter
A4G20_RS08650	ENOG4105DR5	peptidase
A4G20_RS08655	ENOG4105T95	Thiol disulfide interChange protein
A4G20_RS08660	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A4G20_RS08665	ENOG4105UYK	outer membrane protein a
A4G20_RS08670	ENOG4108K4B	hydrolase
A4G20_RS08675	ENOG4105BZU	Histidine kinase
A4G20_RS08685	ENOG4105E5Z	arginine transporter ATP-binding subunit
A4G20_RS08690	ENOG4106PMH	Extracellular solute-binding protein family 3
A4G20_RS08695	ENOG4105GBT	ABC transporter
A4G20_RS08700	ENOG4105DMR	ABC, transporter
A4G20_RS08710	ENOG4105K9H	YciI-like protein
A4G20_RS08720	ENOG4107835	probably involved in intracellular septation (By similarity)
A4G20_RS08730	ENOG4105PQ6	UPF0208 membrane protein
A4G20_RS08735	ENOG4105EYM	Major Facilitator superfamily
A4G20_RS08740	ENOG4105CMR	udp-glucose 4-epimerase
A4G20_RS08745	ENOG4105K70	DNA-binding protein
A4G20_RS08750	ENOG4105R2J	Conserved Protein
A4G20_RS08760	ENOG4105C3M	thioredoxin reductase
A4G20_RS08765	ENOG4105E07	UPF0149 protein
A4G20_RS08770	ENOG41081WQ	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
A4G20_RS08780	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
A4G20_RS08785	ENOG4108BMY	protease
A4G20_RS08800	ENOG4105DJF	DNA polymerase III, delta' subunit
A4G20_RS08815	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A4G20_RS08820	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A4G20_RS08825	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A4G20_RS08830	ENOG4105E96	Colicin v production protein
A4G20_RS08835	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A4G20_RS08840	ENOG4108VD1	dedA family
A4G20_RS08850	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
A4G20_RS08855	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A4G20_RS08860	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
A4G20_RS08870	ENOG4108HPI	phosphatidate Cytidylyltransferase
A4G20_RS08885	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A4G20_RS08890	ENOG4108UUM	single-stranded DNA-binding protein
A4G20_RS08895	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A4G20_RS08900	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
A4G20_RS08915	ENOG4105E02	MotA TolQ exbB proton channel
A4G20_RS08920	ENOG4107YD3	Thioesterase
A4G20_RS08935	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A4G20_RS08940	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A4G20_RS08950	ENOG4105C3F	Signal peptidase i
A4G20_RS08955	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
A4G20_RS08960	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A4G20_RS08970	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A4G20_RS08975	ENOG4105DR9	pseudouridine synthase
A4G20_RS08980	ENOG4105WP7	tRNA pseudouridine synthase C
A4G20_RS09015	ENOG4105MGM	doxx family
A4G20_RS09020	ENOG4105JQN	Transcriptional regulator
A4G20_RS09025	ENOG4105K3M	)-transporter
A4G20_RS09030	ENOG4105BZ4	penicillin-binding protein
A4G20_RS09035	ENOG4105KA0	thioesterase Superfamily protein
A4G20_RS09040	ENOG4105C4R	Atp-dependent dna helicase
A4G20_RS09045	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
A4G20_RS09050	ENOG4105EG2	ABC transporter, permease
A4G20_RS09055	ENOG4105D56	permease protein
A4G20_RS09060	ENOG4107FKK	extracellular solute-binding protein family 1
A4G20_RS09075	ENOG4108IJ9	(ABC) transporter
A4G20_RS09080	ENOG41061ZR	Transcriptional regulator
A4G20_RS09090	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
A4G20_RS09100	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A4G20_RS09110	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
A4G20_RS09115	ENOG4108VVQ	metallophosphoesterase
A4G20_RS09125	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A4G20_RS09130	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
A4G20_RS09135	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A4G20_RS09170	ENOG4105D7Q	type ii secretion system
A4G20_RS09185	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
A4G20_RS09190	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A4G20_RS09195	ENOG4107TSG	Extracellular solute-binding protein, family 5
A4G20_RS09200	ENOG4105D1F	ATP-binding protein
A4G20_RS09205	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
A4G20_RS09210	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A4G20_RS09215	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
A4G20_RS09220	ENOG4105PF3	O-Antigen polymerase
A4G20_RS09225	ENOG4105C8J	)-transporter
A4G20_RS09230	ENOG4105DFE	Dna adenine methylase
A4G20_RS09235	ENOG4105D49	3-dehydroquinate synthase
A4G20_RS09240	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A4G20_RS09245	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
A4G20_RS09255	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
A4G20_RS09260	ENOG4105E98	transcriptional regulator DeoR family
A4G20_RS09265	ENOG4105E70	isomerase
A4G20_RS09270	ENOG4108UZY	PTS System
A4G20_RS09275	ENOG4105ETZ	PTS System
A4G20_RS09280	ENOG4105F3R	pts system mannose fructose sorbose family iid
A4G20_RS09285	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A4G20_RS09305	ENOG4105D2M	Aldolase
A4G20_RS09310	ENOG4105DSY	exodeoxyribonuclease V, gamma
A4G20_RS09335	ENOG4107QUT	magnesium and cobalt transport protein CorA
A4G20_RS09340	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A4G20_RS09345	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A4G20_RS09350	ENOG4105D60	lipoprotein releasing system transmembrane protein
A4G20_RS09355	ENOG4105D82	Glutamate dehydrogenase
A4G20_RS09360	ENOG4108R99	pseudouridine synthase
A4G20_RS09365	ENOG4105WH1	Two component transcriptional regulator luxr family
A4G20_RS09370	ENOG4105WXI	Bacterial OB fold (BOF) protein
A4G20_RS09380	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A4G20_RS09385	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A4G20_RS09395	ENOG4105CBN	LysR family transcriptional regulator
A4G20_RS09425	ENOG4105E4P	ATPase (AAA
A4G20_RS09440	ENOG4105C29	acyl-CoA thioesterase
A4G20_RS09445	ENOG41065U4	response regulator
A4G20_RS09450	ENOG4107R4I	Periplasmic binding protein
A4G20_RS09455	ENOG4105EHG	Permease protein
A4G20_RS09460	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A4G20_RS09465	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
A4G20_RS09480	ENOG4105CXY	transporter
A4G20_RS09485	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
A4G20_RS09490	ENOG4107RK2	ADP-ribose diphosphatase NudE
A4G20_RS09510	ENOG41066UZ	arginase EC 3.5.3.1
A4G20_RS09525	ENOG4108TVJ	Nitroreductase
A4G20_RS09530	ENOG4105E4F	Isochorismate synthase
A4G20_RS09535	ENOG4105CHM	Aminotransferase
A4G20_RS09545	ENOG4105DTR	rard protein
A4G20_RS09550	ENOG4105C25	Primosomal protein n'
A4G20_RS09555	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A4G20_RS09560	ENOG4105M2J	Glutaredoxin
A4G20_RS09570	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
A4G20_RS09575	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A4G20_RS09580	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
A4G20_RS09585	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
A4G20_RS09590	ENOG4105CN1	protease
A4G20_RS09595	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
A4G20_RS09600	ENOG4105EAQ	(twin-arginine translocation) pathway signal
A4G20_RS09605	ENOG4105C5X	domain protein
A4G20_RS09610	ENOG4105DHJ	ABC, transporter
A4G20_RS09615	ENOG4105CY3	ABC transporter, permease
A4G20_RS09620	ENOG4107PE3	Mammalian cell entry related domain protein
A4G20_RS09625	ENOG4105E3I	toluene tolerance
A4G20_RS09635	ENOG4105VFK	BolA family
A4G20_RS09640	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A4G20_RS09645	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
A4G20_RS09650	ENOG4105CAK	Cell division ATP-binding protein ftsE
A4G20_RS09655	ENOG4105K63	Thioredoxin
A4G20_RS09660	ENOG4105CTB	Polyprenyl synthetase
A4G20_RS09670	ENOG4105QVC	MOSC domain-containing protein
A4G20_RS09675	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A4G20_RS09695	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
A4G20_RS09700	ENOG4105W39	Membrane
A4G20_RS09750	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4G20_RS09755	ENOG4105JC1	sterol-binding domain protein
A4G20_RS09770	ENOG4105N21	Membrane
A4G20_RS09780	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A4G20_RS09785	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
A4G20_RS09790	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A4G20_RS09805	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A4G20_RS09810	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A4G20_RS09815	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A4G20_RS09820	ENOG4105VIE	preprotein translocase, subunit YajC
A4G20_RS09825	ENOG4108UUE	Transcriptional regulator
A4G20_RS09835	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A4G20_RS09840	ENOG4105EU0	Major facilitator Superfamily
A4G20_RS09850	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A4G20_RS09855	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
A4G20_RS09860	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A4G20_RS09865	ENOG4107QR8	Thioredoxin
A4G20_RS09875	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
A4G20_RS09880	ENOG4105ECP	epimerase
A4G20_RS09890	ENOG41083KI	ribonuclease, T2
A4G20_RS09895	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
A4G20_RS09900	ENOG4105JIM	Phosphatidylserine synthase
A4G20_RS09905	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A4G20_RS09920	ENOG4105DTN	riboflavin biosynthesis protein ribF
A4G20_RS09925	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A4G20_RS09930	ENOG4105DFS	Conserved Protein
A4G20_RS09935	ENOG4108UJU	UPF0301 protein
A4G20_RS09950	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
A4G20_RS09955	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A4G20_RS09960	ENOG4108URH	decarboxylase
A4G20_RS09965	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
A4G20_RS09970	ENOG4105CWC	Acetylornithine deacetylase
A4G20_RS09975	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A4G20_RS09985	ENOG4105ECF	c-methyltransferase
A4G20_RS09990	ENOG410601J	HemY protein
A4G20_RS10000	ENOG4105EPW	hflc protein
A4G20_RS10005	ENOG4107QJR	hflk protein
A4G20_RS10010	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A4G20_RS10015	ENOG4105C26	Dehydrogenase
A4G20_RS10045	ENOG4105DY8	decarboxylase
A4G20_RS10050	ENOG4108JPW	Aminotransferase
A4G20_RS10055	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A4G20_RS10060	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
A4G20_RS10065	ENOG4105YK5	50S ribosomal protein L36
A4G20_RS10070	ENOG4105NRA	50s ribosomal protein l31 type b
A4G20_RS10075	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A4G20_RS10080	ENOG4105ESV	Glycosyl transferase, family 4
A4G20_RS10085	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A4G20_RS10090	ENOG4107RUZ	Sss sodium solute transporter superfamily
A4G20_RS10125	ENOG4105C4X	radical SAM domain protein
A4G20_RS10130	ENOG4105CMG	Carbohydrate kinase
A4G20_RS10140	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
A4G20_RS10145	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A4G20_RS10150	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
A4G20_RS10155	ENOG4108R66	Conserved Protein
A4G20_RS10165	ENOG4105J4Q	Transcriptional regulator
A4G20_RS10175	ENOG4105DA4	cytochrome c-type biogenesis protein
A4G20_RS10180	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
A4G20_RS10185	ENOG4105D2N	Aldolase
A4G20_RS10190	ENOG4105BZA	Phosphoglycerate kinase
A4G20_RS10195	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
A4G20_RS10200	ENOG4107YZP	Rhodanese domain protein
A4G20_RS10205	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A4G20_RS10210	ENOG4105EMU	Dehydrogenase
A4G20_RS10215	ENOG4105EQ2	LysR family Transcriptional regulator
A4G20_RS10225	ENOG4105E4P	ATPase (AAA
A4G20_RS10230	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
A4G20_RS10240	ENOG4107QRG	dna polymerase iii
A4G20_RS10245	ENOG4108BPE	-transporting atpase
A4G20_RS10250	ENOG4105EAH	synthase
A4G20_RS10255	ENOG4107T0D	ABC, transporter
A4G20_RS10260	ENOG4106SMU	thiamine transporter membrane protein
A4G20_RS10265	ENOG4105DAA	L-lactate
A4G20_RS10270	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
A4G20_RS10280	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
A4G20_RS10305	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A4G20_RS10310	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A4G20_RS10325	ENOG4105C9K	Endothelin-converting enzyme 1
A4G20_RS10330	ENOG4105DMQ	Methyltransferase
A4G20_RS10335	ENOG4108JQC	penicillin-binding protein 1A
A4G20_RS10360	ENOG4105E4G	Type IV pilus
A4G20_RS10365	ENOG4107YIM	Involved in the transcription termination process (By similarity)
A4G20_RS10370	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A4G20_RS10375	ENOG4108ZAI	phosphatidylglycerophosphatase a
A4G20_RS10380	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
A4G20_RS10385	ENOG4105C94	Transporter
A4G20_RS10390	ENOG4105C94	Transporter
A4G20_RS10400	ENOG4108VW9	Membrane
A4G20_RS10405	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A4G20_RS10410	ENOG4105NNH	LexA regulated protein
A4G20_RS10415	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
A4G20_RS10420	ENOG41090R7	Ferric uptake
A4G20_RS10425	ENOG4105DY2	Paraquat-inducible protein b
A4G20_RS10430	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
A4G20_RS10435	ENOG4105BZ1	(ABC) transporter
A4G20_RS10440	ENOG4106WTF	Glycosyl transferase, family 2
A4G20_RS10445	ENOG4105CPK	Glycosyl transferase (Group 1
A4G20_RS10455	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A4G20_RS10460	ENOG4105CBX	hi0933 family
A4G20_RS10465	ENOG4105GPY	SprT protein
A4G20_RS10470	ENOG4105EIB	trna rrna methyltransferase
A4G20_RS10475	ENOG4105EEI	dihydropteroate synthase
A4G20_RS10480	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A4G20_RS10505	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A4G20_RS10510	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A4G20_RS10515	ENOG4108R3E	Dna-3-methyladenine glycosylase i
A4G20_RS10520	ENOG4108K5P	(LipO)protein
A4G20_RS10525	ENOG4108K5P	(LipO)protein
A4G20_RS10530	ENOG4108UM1	dedA family
A4G20_RS10535	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A4G20_RS10545	ENOG4105HF0	Membrane
A4G20_RS10555	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
A4G20_RS10560	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A4G20_RS10570	ENOG4105C2C	drug resistance transporter, Bcr CflA
A4G20_RS10580	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A4G20_RS10585	ENOG4105I08	Pseudouridine synthase
A4G20_RS10595	ENOG4108Q67	UPF0319 protein
A4G20_RS10600	ENOG4108JU5	Magnesium and cobalt efflux protein
A4G20_RS10605	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A4G20_RS10635	ENOG4105C2D	reductase
A4G20_RS10645	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A4G20_RS10715	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A4G20_RS10740	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A4G20_RS10755	ENOG4105CJ1	ABC, transporter
A4G20_RS10760	ENOG4108KYE	ABC-2 type transporter
A4G20_RS10780	ENOG4107QXK	peptidase
A4G20_RS10800	ENOG4105CI3	gtp-binding protein typa
A4G20_RS10810	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A4G20_RS10820	ENOG4105CPF	Cell wall formation (By similarity)
A4G20_RS10835	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A4G20_RS10840	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A4G20_RS10845	ENOG4105BZG	amino acid carrier protein
A4G20_RS10890	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
A4G20_RS10895	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
A4G20_RS10905	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A4G20_RS10910	ENOG4105Y3E	Modulates RecA activity (By similarity)
A4G20_RS10915	ENOG41060QA	UPF0267 protein
A4G20_RS10930	ENOG4105E2X	shikimate dehydrogenase
A4G20_RS10935	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
A4G20_RS10940	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
A4G20_RS10945	ENOG4105CDA	abc transporter atp-binding protein
A4G20_RS10950	ENOG4105E5Q	amino acid AbC transporter
A4G20_RS10955	ENOG4105EAB	amino acid AbC transporter
A4G20_RS10965	ENOG4105D4A	Cell wall formation (By similarity)
A4G20_RS10975	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
A4G20_RS10995	ENOG4105C03	ribonuclease
A4G20_RS11000	ENOG4105C8J	)-transporter
A4G20_RS11010	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A4G20_RS11020	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
A4G20_RS11025	ENOG4105YP7	UPF0270 protein
A4G20_RS11035	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
A4G20_RS11040	ENOG4107S2Z	UPF0761 membrane protein
A4G20_RS11045	ENOG4105MJ9	esterase
A4G20_RS11050	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
A4G20_RS11055	ENOG4105CTS	PTS system mannitol-specific
A4G20_RS11060	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
A4G20_RS11065	ENOG4105E61	Mannitol repressor protein
A4G20_RS11070	ENOG4105EM2	membrane
A4G20_RS11090	ENOG4105C44	Serine transporter
A4G20_RS11095	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A4G20_RS11100	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)