locus-tag	class	description
GT391_RS00020	COG2910	NAD(P)H-binding
GT391_RS00025	COG0583	DNA-binding transcription factor activity
GT391_RS00035	COG3615	Tellurite resistance protein tehB
GT391_RS00045	COG2190	(PTS) system
GT391_RS00045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT391_RS00045	COG1263	PTS System
GT391_RS00050	COG2723	6-phospho-beta-galactosidase activity
GT391_RS00060	COG1840	ABC-type Fe3 transport system, periplasmic component
GT391_RS00065	COG4208	sulfate ABC transporter
GT391_RS00070	COG3842	ATPase activity
GT391_RS00085	COG3718	enzyme involved in inositol metabolism
GT391_RS00095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT391_RS00105	COG1172	Belongs to the binding-protein-dependent transport system permease family
GT391_RS00115	COG1879	ABC-type sugar transport system periplasmic component
GT391_RS00120	COG0673	inositol 2-dehydrogenase activity
GT391_RS00125	COG3962	Belongs to the TPP enzyme family
GT391_RS00155	COG3706	GGDEF domain
GT391_RS00160	COG3711	transcriptional antiterminator
GT391_RS00165	COG2723	6-phospho-beta-galactosidase activity
GT391_RS00175	COG1605	Chorismate mutase
GT391_RS00180	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT391_RS00205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GT391_RS00230	COG1216	Glycosyl transferase, family 2
GT391_RS00235	COG1216	Glycosyl transferase, family 2
GT391_RS00235	COG1442	glycosyl transferase family 8
GT391_RS00255	COG2244	polysaccharide biosynthetic process
GT391_RS00275	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GT391_RS00280	COG0489	protein tyrosine kinase activity
GT391_RS00280	COG3206	protein involved in exopolysaccharide biosynthesis
GT391_RS00295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GT391_RS00300	COG1253	flavin adenine dinucleotide binding
GT391_RS00305	COG3069	C4-dicarboxylate transmembrane transporter activity
GT391_RS00310	COG2982	Protein involved in outer membrane biogenesis
GT391_RS00315	COG0717	Belongs to the dCTP deaminase family
GT391_RS00320	COG0572	uridine kinase
GT391_RS00325	COG0489	protein tyrosine kinase activity
GT391_RS00330	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GT391_RS00330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GT391_RS00335	COG3383	formate dehydrogenase (NAD+) activity
GT391_RS00335	COG0243	molybdopterin cofactor binding
GT391_RS00340	COG0437	4 iron, 4 sulfur cluster binding
GT391_RS00345	COG2864	formate dehydrogenase
GT391_RS00360	COG2706	6-phosphogluconolactonase activity
GT391_RS00375	COG0561	phosphatase activity
GT391_RS00380	COG0837	glucose binding
GT391_RS00385	COG2211	Major facilitator Superfamily
GT391_RS00395	COG0673	inositol 2-dehydrogenase activity
GT391_RS00410	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GT391_RS00415	COG4149	molybdate abc transporter
GT391_RS00420	COG0725	ABC transporter, periplasmic molybdate-binding protein
GT391_RS00430	COG3585	molybdate ion transport
GT391_RS00430	COG2005	Transcriptional regulator
GT391_RS00435	COG1119	ATPase activity
GT391_RS00440	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GT391_RS00445	COG2017	converts alpha-aldose to the beta-anomer
GT391_RS00465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT391_RS00470	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT391_RS00475	COG0588	phosphoglycerate mutase activity
GT391_RS00480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GT391_RS00485	COG1230	cation diffusion facilitator family transporter
GT391_RS00495	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GT391_RS00505	COG1811	Na channel or pump
GT391_RS00525	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GT391_RS00530	COG2885	chlorophyll binding
GT391_RS00535	COG0823	Involved in the tonB-independent uptake of proteins
GT391_RS00540	COG3064	Membrane
GT391_RS00545	COG0848	biopolymer transport protein
GT391_RS00550	COG0811	peptide transport
GT391_RS00555	COG0824	Thioesterase
GT391_RS00560	COG3790	cyd operon protein YbgE
GT391_RS00565	COG4890	Cyd operon protein YbgT
GT391_RS00570	COG1294	oxidase, subunit
GT391_RS00575	COG1271	oxidase subunit
GT391_RS00580	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GT391_RS00585	COG0045	succinate-CoA ligase (ADP-forming) activity
GT391_RS00590	COG0508	dehydrogenase complex catalyzes the overall conversion of
GT391_RS00595	COG0567	Dehydrogenase, E1 component
GT391_RS00600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GT391_RS00605	COG1053	succinate dehydrogenase
GT391_RS00610	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GT391_RS00615	COG2009	succinate dehydrogenase
GT391_RS00630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GT391_RS00635	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GT391_RS00640	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GT391_RS00645	COG1984	allophanate hydrolase subunit 2
GT391_RS00650	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GT391_RS00655	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GT391_RS00660	COG0415	Belongs to the DNA photolyase family
GT391_RS00665	COG3272	Protein of unknown function (DUF1722)
GT391_RS00680	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GT391_RS00685	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GT391_RS00690	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GT391_RS00695	COG2205	protein histidine kinase activity
GT391_RS00700	COG0745	RESPONSE REGULATOR receiver
GT391_RS00710	COG0033	Phosphoglucomutase
GT391_RS00715	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GT391_RS00720	COG0596	Alpha beta hydrolase
GT391_RS00730	COG0840	transmembrane signaling receptor activity
GT391_RS00735	COG0716	FMN binding
GT391_RS00740	COG0735	belongs to the Fur family
GT391_RS00745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GT391_RS00750	COG1263	PTS System
GT391_RS00750	COG2190	(PTS) system
GT391_RS00750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT391_RS00755	COG0363	glucosamine-6-phosphate deaminase activity
GT391_RS00760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GT391_RS00765	COG1940	carbohydrate kinase activity
GT391_RS00765	COG1846	Transcriptional regulator
GT391_RS00770	COG0367	asparagine synthase
GT391_RS00825	COG4974	Belongs to the 'phage' integrase family
GT391_RS00835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GT391_RS00840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GT391_RS00845	COG1702	phosphate starvation-inducible protein PhoH
GT391_RS00850	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GT391_RS00855	COG4535	Mg2 and Co2 transporter CorC
GT391_RS00860	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GT391_RS00870	COG0765	amino acid transport
GT391_RS00875	COG0765	amino acid transport
GT391_RS00880	COG1126	abc transporter atp-binding protein
GT391_RS00885	COG2888	peptidyl-tyrosine sulfation
GT391_RS00890	COG0495	leucyl-tRNA aminoacylation
GT391_RS00895	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GT391_RS00900	COG1466	dna polymerase III delta subunit
GT391_RS00905	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GT391_RS00910	COG0799	negative regulation of ribosome biogenesis
GT391_RS00915	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GT391_RS00920	COG0768	penicillin binding
GT391_RS00925	COG0772	Belongs to the SEDS family
GT391_RS00930	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GT391_RS00935	COG1686	Belongs to the peptidase S11 family
GT391_RS00940	COG2921	Belongs to the UPF0250 family
GT391_RS00945	COG0321	lipoyl(octanoyl) transferase activity
GT391_RS00950	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GT391_RS00955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GT391_RS00960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GT391_RS00965	COG1278	Cold shock
GT391_RS00970	COG1794	racemase activity, acting on amino acids and derivatives
GT391_RS00975	COG4625	pathogenesis
GT391_RS00975	COG3240	lipase activity
GT391_RS00985	COG1393	Belongs to the ArsC family
GT391_RS00990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT391_RS00995	COG1876	peptidase activity
GT391_RS01005	COG0583	DNA-binding transcription factor activity
GT391_RS01010	COG2851	Citrate transporter
GT391_RS01025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GT391_RS01030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GT391_RS01035	COG0183	Belongs to the thiolase family
GT391_RS01045	COG0400	carboxylic ester hydrolase activity
GT391_RS01050	COG3813	Protein conserved in bacteria
GT391_RS01060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GT391_RS01070	COG4178	(ABC) transporter
GT391_RS01075	COG4774	siderophore transport
GT391_RS01080	COG1595	DNA-templated transcription, initiation
GT391_RS01085	COG3712	iron ion homeostasis
GT391_RS01090	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GT391_RS01105	COG0312	modulator of DNA gyrase
GT391_RS01110	COG0312	modulator of DNA gyrase
GT391_RS01115	COG3118	belongs to the thioredoxin family
GT391_RS01120	COG1444	tRNA N-acetyltransferase activity
GT391_RS01125	COG2707	UPF0756 membrane protein
GT391_RS01130	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GT391_RS01135	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GT391_RS01145	COG2716	regulation of RNA biosynthetic process
GT391_RS01150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GT391_RS01155	COG4783	chaperone-mediated protein folding
GT391_RS01160	COG1393	Belongs to the ArsC family
GT391_RS01165	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GT391_RS01170	COG2233	PERMEase
GT391_RS01175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GT391_RS01180	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GT391_RS01185	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GT391_RS01200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GT391_RS01210	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GT391_RS01215	COG4181	ATPase activity
GT391_RS01220	COG2755	lipolytic protein G-D-S-L family
GT391_RS01225	COG0300	oxidoreductase activity
GT391_RS01230	COG3118	belongs to the thioredoxin family
GT391_RS01240	COG0814	amino acid
GT391_RS01250	COG0753	catalase activity
GT391_RS01260	COG1441	menaquinone biosynthetic process
GT391_RS01265	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GT391_RS01270	COG0596	Alpha beta hydrolase
GT391_RS01275	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GT391_RS01280	COG1169	isochorismate synthase
GT391_RS01285	COG2223	nitrite transmembrane transporter activity
GT391_RS01290	COG0642	Histidine kinase
GT391_RS01290	COG2198	Histidine kinase
GT391_RS01295	COG2197	response regulator
GT391_RS01300	COG0784	Response regulator, receiver
GT391_RS01300	COG2205	protein histidine kinase activity
GT391_RS01310	COG1473	amidohydrolase
GT391_RS01315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GT391_RS01320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GT391_RS01325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GT391_RS01330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GT391_RS01335	COG0330	HflC and HflK could
GT391_RS01340	COG1585	Membrane protein implicated in regulation of membrane protease activity
GT391_RS01350	COG2217	Heavy metal translocating P-type atpase
GT391_RS01355	COG3735	TraB family
GT391_RS01365	COG5434	Belongs to the glycosyl hydrolase 28 family
GT391_RS01370	COG0523	cobalamin synthesis protein
GT391_RS01375	COG2879	small protein
GT391_RS01380	COG1966	Carbon starvation protein
GT391_RS01395	COG0737	Belongs to the 5'-nucleotidase family
GT391_RS01400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GT391_RS01400	COG4651	solute:proton antiporter activity
GT391_RS01405	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GT391_RS01410	COG0563	adenylate kinase activity
GT391_RS01415	COG0326	Molecular chaperone. Has ATPase activity
GT391_RS01420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GT391_RS01425	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GT391_RS01435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GT391_RS01440	COG2832	Protein of unknown function (DUF454)
GT391_RS01455	COG1309	transcriptional regulator
GT391_RS01460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT391_RS01465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT391_RS01470	COG0254	rRNA binding
GT391_RS01475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GT391_RS01495	COG3695	enzyme binding
GT391_RS01500	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GT391_RS01505	COG1946	Acyl-CoA thioesterase
GT391_RS01510	COG0004	ammonium transporteR
GT391_RS01515	COG0347	Belongs to the P(II) protein family
GT391_RS01520	COG1132	(ABC) transporter
GT391_RS01525	COG1132	(ABC) transporter
GT391_RS01530	COG1522	sequence-specific DNA binding
GT391_RS01540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GT391_RS01545	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GT391_RS01550	COG0824	Thioesterase
GT391_RS01555	COG1555	photosystem II stabilization
GT391_RS01560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT391_RS01565	COG0776	regulation of translation
GT391_RS01570	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GT391_RS01575	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GT391_RS01580	COG0740	serine-type endopeptidase activity
GT391_RS01585	COG0544	peptidyl-prolyl cis-trans isomerase activity
GT391_RS01590	COG0271	Belongs to the BolA IbaG family
GT391_RS01595	COG3056	Lipoprotein
GT391_RS01600	COG2223	nitrite transmembrane transporter activity
GT391_RS01605	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GT391_RS01610	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GT391_RS01615	COG1845	cytochrome c oxidase, subunit III
GT391_RS01620	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GT391_RS01625	COG0109	protoheme IX farnesyltransferase activity
GT391_RS01630	COG2814	Major facilitator Superfamily
GT391_RS01635	COG1666	GTP binding
GT391_RS01640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GT391_RS01645	COG0693	protein deglycase activity
GT391_RS01650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GT391_RS01650	COG0301	tRNA thio-modification
GT391_RS01655	COG1722	exodeoxyribonuclease VII activity
GT391_RS01660	COG0142	geranyltranstransferase activity
GT391_RS01665	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GT391_RS01670	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GT391_RS01675	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GT391_RS01680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GT391_RS01685	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GT391_RS01690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT391_RS01690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT391_RS01695	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GT391_RS01700	COG4238	major outer membrane lipoprotein
GT391_RS01705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GT391_RS01710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GT391_RS01715	COG1862	Preprotein translocase
GT391_RS01720	COG0343	queuine tRNA-ribosyltransferase activity
GT391_RS01810	COG1783	phage Terminase large subunit
GT391_RS01845	COG3772	lysozyme
GT391_RS01910	COG0305	Participates in initiation and elongation during chromosome replication
GT391_RS02035	COG0582	viral genome integration into host DNA
GT391_RS02040	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GT391_RS02045	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GT391_RS02050	COG0450	alkyl hydroperoxide reductase
GT391_RS02055	COG0668	transmembrane transport
GT391_RS02065	COG1114	Component of the transport system for branched-chain amino acids
GT391_RS02070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GT391_RS02090	COG0420	3'-5' exonuclease activity
GT391_RS02095	COG0419	ATPase involved in DNA repair
GT391_RS02100	COG1940	carbohydrate kinase activity
GT391_RS02105	COG2974	May be involved in recombination
GT391_RS02115	COG2188	Transcriptional regulator
GT391_RS02120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT391_RS02125	COG1397	ADP-ribosylglycohydrolase
GT391_RS02130	COG2211	Major facilitator Superfamily
GT391_RS02135	COG3123	guanosine phosphorylase activity
GT391_RS02140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GT391_RS02150	COG4615	Cyclic peptide transporter
GT391_RS02180	COG5297	Belongs to the glycosyl hydrolase family 6
GT391_RS02185	COG1312	Catalyzes the dehydration of D-mannonate
GT391_RS02190	COG2186	Transcriptional regulator
GT391_RS02220	COG0583	DNA-binding transcription factor activity
GT391_RS02230	COG2951	lytic endotransglycosylase activity
GT391_RS02235	COG2824	Alkylphosphonate utilization operon protein PhnA
GT391_RS02240	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GT391_RS02245	COG1595	DNA-templated transcription, initiation
GT391_RS02250	COG3712	iron ion homeostasis
GT391_RS02255	COG4772	TonB-dependent receptor
GT391_RS02260	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GT391_RS02265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT391_RS02270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT391_RS02275	COG1120	ATPase activity
GT391_RS02295	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GT391_RS02305	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GT391_RS02310	COG3015	lipoprotein NlpE involved in copper resistance
GT391_RS02315	COG4681	YaeQ
GT391_RS02325	COG4568	rho-dependent transcription termination
GT391_RS02330	COG0037	tRNA processing
GT391_RS02335	COG0346	lactoylglutathione lyase activity
GT391_RS02340	COG0825	malonyl-CoA metabolic process
GT391_RS02345	COG0587	DNA-directed DNA polymerase activity
GT391_RS02350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GT391_RS02355	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT391_RS02360	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT391_RS02365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GT391_RS02370	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT391_RS02375	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GT391_RS02380	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT391_RS02385	COG0750	zinc metalloprotease
GT391_RS02390	COG0575	Belongs to the CDS family
GT391_RS02395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GT391_RS02400	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GT391_RS02405	COG0233	cytoplasmic translational termination
GT391_RS02410	COG0528	UMP kinase activity
GT391_RS02415	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GT391_RS02420	COG0052	Belongs to the universal ribosomal protein uS2 family
GT391_RS02425	COG0024	Methionine aminopeptidase
GT391_RS02430	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GT391_RS02435	COG2171	N-acyltransferase activity
GT391_RS02475	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GT391_RS02475	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GT391_RS02480	COG1611	Belongs to the LOG family
GT391_RS02485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GT391_RS02490	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GT391_RS02495	COG2363	Small membrane protein
GT391_RS02500	COG0583	DNA-binding transcription factor activity
GT391_RS02510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GT391_RS02515	COG2166	iron-sulfur cluster assembly
GT391_RS02520	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GT391_RS02530	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GT391_RS02550	COG0860	N-Acetylmuramoyl-L-alanine amidase
GT391_RS02555	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GT391_RS02555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GT391_RS02565	COG1609	Transcriptional regulator
GT391_RS02570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GT391_RS02575	COG1074	ATP-dependent DNA helicase activity
GT391_RS02580	COG1025	Belongs to the peptidase M16 family
GT391_RS02585	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GT391_RS02600	COG4795	General secretion pathway protein
GT391_RS02620	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GT391_RS02625	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GT391_RS02635	COG0494	nUDIX hydrolase
GT391_RS02640	COG3066	DNA modification
GT391_RS02645	COG0861	Integral membrane protein TerC family
GT391_RS02655	COG0667	Aldo Keto reductase
GT391_RS02665	COG3171	Protein conserved in bacteria
GT391_RS02670	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GT391_RS02680	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GT391_RS02685	COG0741	lytic transglycosylase activity
GT391_RS02690	COG2169	Transcriptional regulator
GT391_RS02690	COG1917	Cupin 2, conserved barrel domain protein
GT391_RS02700	COG5564	TIM-barrel signal transduction protein
GT391_RS02705	COG5441	Belongs to the UPF0261 family
GT391_RS02715	COG1028	Short-chain dehydrogenase reductase Sdr
GT391_RS02725	COG1982	Orn Lys Arg decarboxylase major
GT391_RS02735	COG3423	Transcriptional regulator
GT391_RS02765	COG2205	protein histidine kinase activity
GT391_RS02770	COG2207	Transcriptional regulator
GT391_RS02775	COG2814	Major facilitator Superfamily
GT391_RS02785	COG2249	NAD(P)H dehydrogenase (quinone) activity
GT391_RS02840	COG3121	Chaperone
GT391_RS02870	COG4948	Mandelate Racemase Muconate Lactonizing
GT391_RS02875	COG4773	Receptor
GT391_RS02885	COG0583	DNA-binding transcription factor activity
GT391_RS02910	COG2814	Major facilitator Superfamily
GT391_RS02930	COG0811	peptide transport
GT391_RS02945	COG1802	Transcriptional regulator
GT391_RS02950	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GT391_RS02950	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GT391_RS02970	COG0246	Mannitol dehydrogenase
GT391_RS02975	COG0477	Major facilitator Superfamily
GT391_RS02980	COG1063	alcohol dehydrogenase
GT391_RS02985	COG4948	Mandelate Racemase Muconate Lactonizing
GT391_RS02990	COG0583	DNA-binding transcription factor activity
GT391_RS03000	COG0437	4 iron, 4 sulfur cluster binding
GT391_RS03005	COG3301	Polysulphide reductase, NrfD
GT391_RS03010	COG0477	Major facilitator Superfamily
GT391_RS03015	COG3976	FMN-binding domain protein
GT391_RS03015	COG1053	succinate dehydrogenase
GT391_RS03015	COG0431	NADPH-dependent FMN reductase
GT391_RS03020	COG1053	succinate dehydrogenase
GT391_RS03030	COG2169	Transcriptional regulator
GT391_RS03030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GT391_RS03055	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GT391_RS03055	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GT391_RS03060	COG3604	Transcriptional regulator
GT391_RS03065	COG1773	rubredoxin
GT391_RS03065	COG0426	domain, Protein
GT391_RS03070	COG0446	pyridine nucleotide-disulphide oxidoreductase
GT391_RS03080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GT391_RS03090	COG0531	amino acid
GT391_RS03095	COG3115	cell septum assembly
GT391_RS03100	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GT391_RS03105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GT391_RS03110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT391_RS03120	COG2190	(PTS) system
GT391_RS03125	COG2205	protein histidine kinase activity
GT391_RS03130	COG0745	RESPONSE REGULATOR receiver
GT391_RS03135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT391_RS03140	COG0577	efflux transmembrane transporter activity
GT391_RS03140	COG1136	(ABC) transporter
GT391_RS03145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GT391_RS03150	COG4208	sulfate ABC transporter
GT391_RS03155	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GT391_RS03160	COG4150	thiosulfate binding
GT391_RS03165	COG2837	iron assimilation
GT391_RS03175	COG4178	(ABC) transporter
GT391_RS03180	COG0612	Peptidase, M16
GT391_RS03195	COG0456	acetyltransferase
GT391_RS03200	COG0408	coproporphyrinogen oxidase activity
GT391_RS03205	COG1671	Belongs to the UPF0178 family
GT391_RS03210	COG0814	amino acid
GT391_RS03225	COG2084	Dehydrogenase
GT391_RS03230	COG1082	Xylose isomerase domain protein TIM barrel
GT391_RS03235	COG0149	triose-phosphate isomerase activity
GT391_RS03240	COG2376	Dihydroxyacetone kinase
GT391_RS03250	COG0698	ribose 5-phosphate isomerase
GT391_RS03255	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GT391_RS03260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GT391_RS03265	COG2190	(PTS) system
GT391_RS03265	COG1263	PTS System
GT391_RS03265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT391_RS03270	COG2723	6-phospho-beta-galactosidase activity
GT391_RS03275	COG3711	transcriptional antiterminator
GT391_RS03280	COG1609	Transcriptional regulator
GT391_RS03310	COG0494	nUDIX hydrolase
GT391_RS03320	COG0477	Major facilitator Superfamily
GT391_RS03325	COG1942	4-Oxalocrotonate Tautomerase
GT391_RS03330	COG1914	H( )-stimulated, divalent metal cation uptake system
GT391_RS03335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GT391_RS03340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GT391_RS03345	COG0497	DNA recombination
GT391_RS03355	COG2914	Belongs to the UPF0125 (RnfH) family
GT391_RS03360	COG2867	negative regulation of translational initiation
GT391_RS03365	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GT391_RS03375	COG0582	viral genome integration into host DNA
GT391_RS03440	COG4453	Protein conserved in bacteria
GT391_RS03455	COG2026	Addiction module toxin, RelE StbE family
GT391_RS03480	COG1280	lysine exporter protein (LysE YggA)
GT391_RS03500	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT391_RS03500	COG1013	pyruvate-flavodoxin oxidoreductase activity
GT391_RS03500	COG0674	pyruvate-flavodoxin oxidoreductase activity
GT391_RS03500	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GT391_RS03505	COG3038	cytochrome b561
GT391_RS03510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GT391_RS03515	COG1376	ErfK ybiS ycfS ynhG family protein
GT391_RS03520	COG2873	o-acetylhomoserine
GT391_RS03525	COG0246	Mannitol dehydrogenase
GT391_RS03545	COG3712	iron ion homeostasis
GT391_RS03555	COG4774	siderophore transport
GT391_RS03565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GT391_RS03570	COG3162	membrane
GT391_RS03575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT391_RS03580	COG5464	transposase or invertase
GT391_RS03660	COG4964	Belongs to the GSP D family
GT391_RS03680	COG5002	protein histidine kinase activity
GT391_RS03680	COG3850	Histidine kinase
GT391_RS03690	COG0025	NhaP-type Na H and K H
GT391_RS03695	COG2252	PERMEase
GT391_RS03720	COG1953	Uracil, thiamine, allantoin
GT391_RS03725	COG1560	Kdo2-lipid A biosynthetic process
GT391_RS03735	COG4319	ketosteroid isomerase
GT391_RS03750	COG2207	Transcriptional regulator
GT391_RS03755	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GT391_RS03765	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GT391_RS03770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GT391_RS03775	COG4974	Belongs to the 'phage' integrase family
GT391_RS03780	COG0477	Major facilitator Superfamily
GT391_RS03790	COG0716	FMN binding
GT391_RS03800	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GT391_RS03810	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GT391_RS03815	COG0354	folic acid binding
GT391_RS03820	COG1272	protein, Hemolysin III
GT391_RS03840	COG2211	Major facilitator Superfamily
GT391_RS03845	COG1653	transport
GT391_RS03850	COG3842	ATPase activity
GT391_RS03855	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GT391_RS03865	COG1175	transmembrane transport
GT391_RS03875	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GT391_RS03875	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GT391_RS03880	COG0509	glycine decarboxylation via glycine cleavage system
GT391_RS03885	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GT391_RS03890	COG1454	alcohol dehydrogenase
GT391_RS03940	COG0656	L-ascorbic acid biosynthetic process
GT391_RS03945	COG2813	Specifically methylates the guanine in position
GT391_RS03950	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GT391_RS03955	COG0456	acetyltransferase
GT391_RS03965	COG1595	DNA-templated transcription, initiation
GT391_RS03970	COG3712	iron ion homeostasis
GT391_RS03980	COG4178	(ABC) transporter
GT391_RS03985	COG0813	purine-nucleoside phosphorylase activity
GT391_RS03990	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GT391_RS03995	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GT391_RS04000	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GT391_RS04005	COG1473	amidohydrolase
GT391_RS04010	COG2827	Endonuclease containing a URI domain
GT391_RS04015	COG3153	acetyltransferase
GT391_RS04035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT391_RS04040	COG0513	Belongs to the DEAD box helicase family
GT391_RS04055	COG1185	polyribonucleotide nucleotidyltransferase activity
GT391_RS04060	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GT391_RS04065	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GT391_RS04070	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GT391_RS04075	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GT391_RS04085	COG0779	Required for maturation of 30S ribosomal subunits
GT391_RS04095	COG2197	response regulator
GT391_RS04115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GT391_RS04155	COG2130	NADP-dependent
GT391_RS04165	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GT391_RS04170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GT391_RS04175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GT391_RS04180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GT391_RS04185	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GT391_RS04190	COG1534	Rna-binding protein
GT391_RS04195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GT391_RS04200	COG2027	D-alanyl-D-alanine carboxypeptidase
GT391_RS04205	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GT391_RS04210	COG0697	spore germination
GT391_RS04215	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GT391_RS04220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GT391_RS04225	COG0142	geranyltranstransferase activity
GT391_RS04240	COG3423	Transcriptional regulator
GT391_RS04245	COG0039	L-malate dehydrogenase activity
GT391_RS04250	COG1438	arginine binding
GT391_RS04255	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GT391_RS04265	COG0358	DNA primase activity
GT391_RS04270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GT391_RS04275	COG3663	DNA glycosylase
GT391_RS04290	COG0583	DNA-binding transcription factor activity
GT391_RS04295	COG0693	protein deglycase activity
GT391_RS04305	COG3119	arylsulfatase activity
GT391_RS04310	COG0641	radical SAM
GT391_RS04315	COG3119	arylsulfatase activity
GT391_RS04320	COG3119	arylsulfatase activity
GT391_RS04335	COG2199	diguanylate cyclase activity
GT391_RS04340	COG3678	ATP-independent chaperone mediated protein folding
GT391_RS04350	COG1902	pentaerythritol trinitrate reductase activity
GT391_RS04350	COG0446	pyridine nucleotide-disulphide oxidoreductase
GT391_RS04355	COG2813	Specifically methylates the guanine in position
GT391_RS04360	COG0673	inositol 2-dehydrogenase activity
GT391_RS04365	COG0861	Integral membrane protein TerC family
GT391_RS04370	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GT391_RS04380	COG2721	sulfolactate sulfo-lyase activity
GT391_RS04385	COG0246	Mannitol dehydrogenase
GT391_RS04390	COG1904	glucuronate isomerase
GT391_RS04395	COG2271	Major facilitator Superfamily
GT391_RS04405	COG0586	Pfam SNARE associated Golgi protein
GT391_RS04415	COG1422	Protein of unknown function (DUF1090)
GT391_RS04420	COG4575	ribosome binding
GT391_RS04425	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GT391_RS04435	COG2259	Doxx family
GT391_RS04440	COG0435	Glutathione S-transferase
GT391_RS04445	COG0583	DNA-binding transcription factor activity
GT391_RS04450	COG1741	Belongs to the pirin family
GT391_RS04455	COG0735	belongs to the Fur family
GT391_RS04460	COG3237	CsbD-like
GT391_RS04465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GT391_RS04470	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GT391_RS04475	COG2937	Belongs to the GPAT DAPAT family
GT391_RS04480	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GT391_RS04490	COG0459	protein refolding
GT391_RS04495	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GT391_RS04510	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GT391_RS04515	COG1324	tolerance protein
GT391_RS04520	COG4232	protein-disulfide reductase activity
GT391_RS04525	COG1309	transcriptional regulator
GT391_RS04535	COG3423	Transcriptional regulator
GT391_RS04610	COG0318	PFAM AMP-dependent synthetase and ligase
GT391_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
GT391_RS04610	COG3321	synthase
GT391_RS04610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GT391_RS04610	COG0300	oxidoreductase activity
GT391_RS04620	COG1028	Short-chain dehydrogenase reductase Sdr
GT391_RS04625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GT391_RS04630	COG1535	isochorismatase
GT391_RS04630	COG3433	isochorismatase activity
GT391_RS04635	COG1021	2,3-dihydroxybenzoate-AMP ligase
GT391_RS04640	COG1169	isochorismate synthase
GT391_RS04650	COG4771	TonB-dependent receptor
GT391_RS04660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GT391_RS04665	COG0084	hydrolase, TatD family'
GT391_RS04675	COG5487	UPF0391 membrane protein
GT391_RS04680	COG2823	Periplasmic or secreted lipoprotein
GT391_RS04685	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GT391_RS04695	COG3726	membrane protein affecting hemolysin expression
GT391_RS04700	COG0560	Phosphoserine phosphatase
GT391_RS04715	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GT391_RS04725	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GT391_RS04730	COG3079	Belongs to the UPF0149 family
GT391_RS04735	COG0006	proline dipeptidase activity
GT391_RS04740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GT391_RS04745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GT391_RS04750	COG3157	Type VI secretion system effector, Hcp
GT391_RS04770	COG2130	NADP-dependent
GT391_RS04775	COG2862	Uncharacterized protein family, UPF0114
GT391_RS04785	COG3477	response to acidic pH
GT391_RS04790	COG0747	negative chemotaxis
GT391_RS04795	COG0601	transmembrane transport
GT391_RS04820	COG1917	Cupin 2, conserved barrel domain protein
GT391_RS04820	COG4977	sequence-specific DNA binding
GT391_RS04825	COG1917	Cupin 2, conserved barrel domain protein
GT391_RS04825	COG2169	Transcriptional regulator
GT391_RS04830	COG1070	Carbohydrate kinase
GT391_RS04835	COG4806	L-rhamnose isomerase
GT391_RS04840	COG0235	Class ii aldolase
GT391_RS04845	COG3254	rhamnose metabolic process
GT391_RS04850	COG0840	transmembrane signaling receptor activity
GT391_RS04860	COG0840	transmembrane signaling receptor activity
GT391_RS04865	COG0288	reversible hydration of carbon dioxide
GT391_RS04870	COG0659	secondary active sulfate transmembrane transporter activity
GT391_RS04890	COG1690	Belongs to the RtcB family
GT391_RS04895	COG4650	regulator
GT391_RS04935	COG0583	DNA-binding transcription factor activity
GT391_RS04950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT391_RS04970	COG2850	peptidyl-arginine hydroxylation
GT391_RS04985	COG0795	lipopolysaccharide-transporting ATPase activity
GT391_RS04990	COG0795	lipopolysaccharide-transporting ATPase activity
GT391_RS04995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GT391_RS05000	COG2927	DNA polymerase III (CHI subunit)
GT391_RS05005	COG0525	valine-tRNA ligase activity
GT391_RS05025	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GT391_RS05045	COG3210	domain, Protein
GT391_RS05050	COG2831	hemolysin activation secretion protein
GT391_RS05055	COG0840	transmembrane signaling receptor activity
GT391_RS05060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GT391_RS05065	COG0501	Belongs to the peptidase M48B family
GT391_RS05080	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GT391_RS05085	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GT391_RS05100	COG2731	YhcH YjgK YiaL family protein
GT391_RS05105	COG0540	Belongs to the ATCase OTCase family
GT391_RS05110	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GT391_RS05120	COG2308	Evidence 4 Homologs of previously reported genes of
GT391_RS05150	COG0702	epimerase
GT391_RS05155	COG3787	Belongs to the UPF0306 family
GT391_RS05160	COG1733	regulation of RNA biosynthetic process
GT391_RS05165	COG2814	Major facilitator Superfamily
GT391_RS05170	COG0076	glutamate decarboxylase activity
GT391_RS05185	COG4680	protein conserved in bacteria
GT391_RS05220	COG0848	biopolymer transport protein
GT391_RS05225	COG0811	peptide transport
GT391_RS05230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT391_RS05250	COG0586	Pfam SNARE associated Golgi protein
GT391_RS05255	COG2207	Transcriptional regulator
GT391_RS05260	COG0778	Nitroreductase
GT391_RS05265	COG1979	alcohol dehydrogenase
GT391_RS05275	COG2188	Transcriptional regulator
GT391_RS05280	COG2132	Multicopper oxidase
GT391_RS05285	COG0204	Acyl-transferase
GT391_RS05290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GT391_RS05300	COG2186	Transcriptional regulator
GT391_RS05310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT391_RS05310	COG3711	transcriptional antiterminator
GT391_RS05315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GT391_RS05315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT391_RS05315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GT391_RS05320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GT391_RS05325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GT391_RS05325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GT391_RS05345	COG0187	DNA topoisomerase II activity
GT391_RS05350	COG3150	esterase
GT391_RS05355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GT391_RS05360	COG3151	Protein conserved in bacteria
GT391_RS05365	COG0494	nUDIX hydrolase
GT391_RS05375	COG5463	Belongs to the UPF0441 family
GT391_RS05380	COG0754	glutathionylspermidine amidase activity
GT391_RS05385	COG3384	dioxygenase
GT391_RS05395	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GT391_RS05400	COG3107	peptidoglycan biosynthetic process
GT391_RS05405	COG0792	nuclease activity
GT391_RS05410	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GT391_RS05415	COG2823	Periplasmic or secreted lipoprotein
GT391_RS05425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GT391_RS05430	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GT391_RS05435	COG5002	protein histidine kinase activity
GT391_RS05435	COG2198	Histidine kinase
GT391_RS05435	COG0784	Response regulator, receiver
GT391_RS05440	COG1242	4 iron, 4 sulfur cluster binding
GT391_RS05445	COG0069	glutamate synthase activity
GT391_RS05445	COG0070	glutamate synthase
GT391_RS05445	COG0067	glutamate synthase
GT391_RS05450	COG0493	'glutamate synthase
GT391_RS05460	COG2969	positive regulation of protein catabolic process
GT391_RS05465	COG0625	glutathione transferase activity
GT391_RS05475	COG2186	Transcriptional regulator
GT391_RS05480	COG1028	Short-chain dehydrogenase reductase Sdr
GT391_RS05485	COG1063	alcohol dehydrogenase
GT391_RS05490	COG0477	Major facilitator Superfamily
GT391_RS05495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GT391_RS05500	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GT391_RS05505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GT391_RS05510	COG3105	Protein conserved in bacteria
GT391_RS05515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GT391_RS05520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GT391_RS05525	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GT391_RS05530	COG5007	Belongs to the BolA IbaG family
GT391_RS05535	COG3113	response to antibiotic
GT391_RS05540	COG2854	intermembrane phospholipid transfer
GT391_RS05545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GT391_RS05550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GT391_RS05555	COG1127	ABC transporter
GT391_RS05560	COG0530	calcium, potassium:sodium antiporter activity
GT391_RS05565	COG0517	IMP dehydrogenase activity
GT391_RS05565	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GT391_RS05570	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GT391_RS05575	COG3117	lipopolysaccharide transmembrane transporter activity
GT391_RS05580	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GT391_RS05585	COG1137	ATPase activity
GT391_RS05590	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GT391_RS05595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GT391_RS05600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT391_RS05605	COG1660	Displays ATPase and GTPase activities
GT391_RS05610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT391_RS05615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GT391_RS05620	COG0312	modulator of DNA gyrase
GT391_RS05625	COG3028	Belongs to the UPF0307 family
GT391_RS05635	COG1289	transmembrane transporter activity
GT391_RS05640	COG1566	PFAM secretion protein HlyD family protein
GT391_RS05650	COG0583	DNA-binding transcription factor activity
GT391_RS05665	COG0312	modulator of DNA gyrase
GT391_RS05670	COG3164	Protein of unknown function
GT391_RS05675	COG1530	ribonuclease E activity
GT391_RS05680	COG0424	maF-like protein
GT391_RS05685	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GT391_RS05690	COG1792	Involved in formation and maintenance of cell shape
GT391_RS05695	COG1077	Cell shape determining protein MreB Mrl
GT391_RS05700	COG2200	EAL domain
GT391_RS05700	COG2199	diguanylate cyclase activity
GT391_RS05705	COG0604	alcohol dehydrogenase
GT391_RS05710	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GT391_RS05715	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GT391_RS05720	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GT391_RS05725	COG0511	ligase activity, forming carbon-carbon bonds
GT391_RS05730	COG0439	Biotin carboxylase
GT391_RS05745	COG0500	methyltransferase
GT391_RS05750	COG1120	ATPase activity
GT391_RS05770	COG3924	membrane
GT391_RS05775	COG4145	pantothenate transmembrane transporter activity
GT391_RS05780	COG2264	protein methyltransferase activity
GT391_RS05795	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GT391_RS05800	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GT391_RS05820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT391_RS05825	COG0765	amino acid transport
GT391_RS05830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT391_RS05835	COG4597	amino acid ABC transporter
GT391_RS05840	COG0765	amino acid transport
GT391_RS05845	COG1126	abc transporter atp-binding protein
GT391_RS05880	COG1739	Uncharacterized protein family UPF0029
GT391_RS05885	COG0006	proline dipeptidase activity
GT391_RS05890	COG1024	Enoyl-CoA hydratase
GT391_RS05890	COG1250	3-hydroxyacyl-CoA dehydrogenase
GT391_RS05895	COG0183	Belongs to the thiolase family
GT391_RS05905	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GT391_RS05910	COG0250	Participates in transcription elongation, termination and antitermination
GT391_RS05920	COG0084	hydrolase, TatD family'
GT391_RS05925	COG0805	protein transport
GT391_RS05930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GT391_RS05935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GT391_RS05940	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GT391_RS05950	COG2226	methyltransferase
GT391_RS05955	COG1322	Protein conserved in bacteria
GT391_RS05960	COG0165	Argininosuccinate lyase
GT391_RS05965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GT391_RS05970	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GT391_RS05975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT391_RS05985	COG4948	Mandelate Racemase Muconate Lactonizing
GT391_RS05990	COG2190	(PTS) system
GT391_RS05990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT391_RS05990	COG1263	PTS System
GT391_RS05995	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GT391_RS06005	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GT391_RS06010	COG0412	Dienelactone hydrolase
GT391_RS06015	COG0840	transmembrane signaling receptor activity
GT391_RS06020	COG0840	transmembrane signaling receptor activity
GT391_RS06025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GT391_RS06030	COG0583	DNA-binding transcription factor activity
GT391_RS06035	COG0697	spore germination
GT391_RS06050	COG1045	serine acetyltransferase
GT391_RS06055	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GT391_RS06060	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GT391_RS06065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GT391_RS06070	COG4942	peptidase
GT391_RS06075	COG2861	carbohydrate metabolic process
GT391_RS06080	COG1063	alcohol dehydrogenase
GT391_RS06085	COG0156	8-amino-7-oxononanoate synthase activity
GT391_RS06090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT391_RS06095	COG0859	PFAM glycosyl transferase family 9
GT391_RS06100	COG0859	PFAM glycosyl transferase family 9
GT391_RS06105	COG3307	-O-antigen
GT391_RS06110	COG0859	PFAM glycosyl transferase family 9
GT391_RS06115	COG0438	transferase activity, transferring glycosyl groups
GT391_RS06150	COG1215	transferase activity, transferring glycosyl groups
GT391_RS06155	COG1519	Transferase
GT391_RS06160	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GT391_RS06165	COG1216	Glycosyl transferase, family 2
GT391_RS06165	COG1442	glycosyl transferase family 8
GT391_RS06170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GT391_RS06175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GT391_RS06180	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GT391_RS06185	COG2003	Belongs to the UPF0758 family
GT391_RS06190	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GT391_RS06195	COG0756	dUTP diphosphatase activity
GT391_RS06200	COG1309	transcriptional regulator
GT391_RS06205	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GT391_RS06210	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GT391_RS06215	COG4948	Mandelate Racemase Muconate Lactonizing
GT391_RS06220	COG4172	Belongs to the ABC transporter superfamily
GT391_RS06225	COG0747	negative chemotaxis
GT391_RS06230	COG0601	transmembrane transport
GT391_RS06235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT391_RS06250	COG1446	asparaginase
GT391_RS06255	COG0583	DNA-binding transcription factor activity
GT391_RS06260	COG1561	YicC-like family, N-terminal region
GT391_RS06305	COG0628	permease
GT391_RS06310	COG0456	acetyltransferase
GT391_RS06310	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GT391_RS06315	COG1304	FMN binding
GT391_RS06320	COG1012	belongs to the aldehyde dehydrogenase family
GT391_RS06330	COG3239	Fatty acid desaturase
GT391_RS06360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT391_RS06365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GT391_RS06370	COG3136	membrane protein required for alginate biosynthesis
GT391_RS06395	COG4677	pectinesterase activity
GT391_RS06400	COG2771	luxR family
GT391_RS06410	COG0137	argininosuccinate synthase activity
GT391_RS06420	COG1609	Transcriptional regulator
GT391_RS06420	COG2207	Transcriptional regulator
GT391_RS06425	COG4214	carbohydrate transport
GT391_RS06430	COG1129	ABC transporter
GT391_RS06435	COG4213	ABC transporter substrate-binding protein
GT391_RS06440	COG2115	Belongs to the xylose isomerase family
GT391_RS06445	COG1070	Carbohydrate kinase
GT391_RS06450	COG3274	enterobacterial common antigen metabolic process
GT391_RS06455	COG1012	belongs to the aldehyde dehydrogenase family
GT391_RS06460	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GT391_RS06465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GT391_RS06470	COG0840	transmembrane signaling receptor activity
GT391_RS06480	COG3722	fumarate hydratase activity
GT391_RS06485	COG0246	Mannitol dehydrogenase
GT391_RS06490	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT391_RS06490	COG2213	PTS system mannitol-specific
GT391_RS06500	COG0751	glycine-tRNA ligase activity
GT391_RS06505	COG0752	glycyl-tRNA synthetase alpha subunit
GT391_RS06510	COG0730	response to heat
GT391_RS06515	COG2818	Glycosylase
GT391_RS06520	COG0456	acetyltransferase
GT391_RS06525	COG0840	transmembrane signaling receptor activity
GT391_RS06530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT391_RS06565	COG4172	Belongs to the ABC transporter superfamily
GT391_RS06570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT391_RS06580	COG3479	Phenolic acid decarboxylase
GT391_RS06590	COG1280	lysine exporter protein (LysE YggA)
GT391_RS06600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GT391_RS06620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GT391_RS06625	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GT391_RS06635	COG2214	Heat shock protein DnaJ domain protein
GT391_RS06640	COG0443	Heat shock 70 kDa protein
GT391_RS06655	COG3712	iron ion homeostasis
GT391_RS06660	COG1595	DNA-templated transcription, initiation
GT391_RS06665	COG1629	transport
GT391_RS06675	COG0742	ribosomal rna small subunit methyltransferase
GT391_RS06680	COG0737	Belongs to the 5'-nucleotidase family
GT391_RS06690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GT391_RS06695	COG0589	response to stress
GT391_RS06705	COG0306	phosphate transporter
GT391_RS06710	COG2081	HI0933 family
GT391_RS06715	COG2200	EAL domain
GT391_RS06730	COG2194	sulfuric ester hydrolase activity
GT391_RS06735	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GT391_RS06740	COG0194	GDP metabolic process
GT391_RS06745	COG1758	RNA polymerase activity
GT391_RS06750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GT391_RS06755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GT391_RS06760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GT391_RS06765	COG2233	PERMEase
GT391_RS06770	COG2982	Protein involved in outer membrane biogenesis
GT391_RS06775	COG0456	acetyltransferase
GT391_RS06780	COG1490	D-aminoacyl-tRNA deacylase activity
GT391_RS06785	COG1011	Hydrolase
GT391_RS06795	COG0174	glutamine synthetase
GT391_RS06800	COG3852	Histidine kinase
GT391_RS06820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GT391_RS06825	COG3078	GTPase activator activity
GT391_RS06835	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GT391_RS06840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GT391_RS06840	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GT391_RS06850	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GT391_RS06855	COG3084	Protein conserved in bacteria
GT391_RS06860	COG0746	molybdenum cofactor guanylyltransferase activity
GT391_RS06865	COG1763	Mo-molybdopterin cofactor biosynthetic process
GT391_RS06895	COG1609	Transcriptional regulator
GT391_RS06900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT391_RS06905	COG1879	ABC-type sugar transport system periplasmic component
GT391_RS06910	COG1172	Belongs to the binding-protein-dependent transport system permease family
GT391_RS06915	COG1129	ABC transporter
GT391_RS06920	COG1869	D-ribose catabolic process
GT391_RS06925	COG3111	PFAM Bacterial OB fold (BOF) protein
GT391_RS06930	COG0745	RESPONSE REGULATOR receiver
GT391_RS06935	COG0642	Histidine kinase
GT391_RS06940	COG3158	transport of potassium into the cell
GT391_RS06945	COG0714	Associated with various cellular activities
GT391_RS06950	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GT391_RS06955	COG2502	aspartate--ammonia ligase
GT391_RS06960	COG1522	sequence-specific DNA binding
GT391_RS06965	COG0716	FMN binding
GT391_RS06970	COG0445	tRNA wobble uridine modification
GT391_RS06975	COG0357	Ribosomal RNA small subunit methyltransferase G
GT391_RS06980	COG3312	ion transport
GT391_RS06985	COG0356	it plays a direct role in the translocation of protons across the membrane
GT391_RS06995	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GT391_RS07000	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GT391_RS07005	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GT391_RS07010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GT391_RS07015	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GT391_RS07020	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GT391_RS07030	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GT391_RS07035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GT391_RS07060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GT391_RS07065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GT391_RS07075	COG0318	PFAM AMP-dependent synthetase and ligase
GT391_RS07080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GT391_RS07080	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GT391_RS07085	COG1216	Glycosyl transferase, family 2
GT391_RS07110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GT391_RS07120	COG1028	Short-chain dehydrogenase reductase Sdr
GT391_RS07135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GT391_RS07140	COG0573	inorganic phosphate transmembrane transporter activity
GT391_RS07145	COG0581	inorganic phosphate transmembrane transporter activity
GT391_RS07150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GT391_RS07160	COG1396	sequence-specific DNA binding
GT391_RS07165	COG3135	benzoate transporter
GT391_RS07170	COG2990	Protein conserved in bacteria
GT391_RS07175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT391_RS07180	COG0765	amino acid transport
GT391_RS07185	COG0765	amino acid transport
GT391_RS07190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT391_RS07195	COG2252	PERMEase
GT391_RS07200	COG2091	lysine biosynthetic process via aminoadipic acid
GT391_RS07205	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GT391_RS07210	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GT391_RS07210	COG0493	'glutamate synthase
GT391_RS07240	COG1733	regulation of RNA biosynthetic process
GT391_RS07245	COG0702	epimerase
GT391_RS07260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GT391_RS07265	COG0706	membrane insertase activity
GT391_RS07275	COG0594	ribonuclease P activity
GT391_RS07280	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GT391_RS07285	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GT391_RS07290	COG0592	DNA-directed DNA polymerase activity
GT391_RS07295	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GT391_RS07300	COG0187	DNA topoisomerase II activity
GT391_RS07315	COG0840	transmembrane signaling receptor activity
GT391_RS07320	COG1609	Transcriptional regulator
GT391_RS07330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GT391_RS07335	COG1447	Phosphotransferase system cellobiose-specific component IIA
GT391_RS07340	COG2723	6-phospho-beta-galactosidase activity
GT391_RS07345	COG0561	phosphatase activity
GT391_RS07355	COG0747	negative chemotaxis
GT391_RS07360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT391_RS07375	COG0601	transmembrane transport
GT391_RS07380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT391_RS07395	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GT391_RS07400	COG2186	Transcriptional regulator
GT391_RS07405	COG3734	2-keto-3-deoxy-galactonokinase
GT391_RS07410	COG0800	Aldolase
GT391_RS07415	COG4948	Mandelate Racemase Muconate Lactonizing
GT391_RS07420	COG2271	Major facilitator Superfamily
GT391_RS07430	COG1116	anion transmembrane transporter activity
GT391_RS07435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT391_RS07440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT391_RS07445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GT391_RS07460	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GT391_RS07460	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GT391_RS07465	COG2723	6-phospho-beta-galactosidase activity
GT391_RS07475	COG0823	Involved in the tonB-independent uptake of proteins
GT391_RS07480	COG5645	(Lipo)protein
GT391_RS07485	COG0071	Belongs to the small heat shock protein (HSP20) family
GT391_RS07490	COG0071	Belongs to the small heat shock protein (HSP20) family
GT391_RS07495	COG0569	domain protein
GT391_RS07495	COG2985	domain, Protein
GT391_RS07500	COG0471	metal ion transport
GT391_RS07505	COG3290	protein histidine kinase activity
GT391_RS07510	COG4565	transcriptional regulatory protein
GT391_RS07530	COG3493	citrate carrier protein
GT391_RS07535	COG0747	negative chemotaxis
GT391_RS07540	COG0601	transmembrane transport
GT391_RS07545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT391_RS07550	COG0444	Belongs to the ABC transporter superfamily
GT391_RS07555	COG4608	Belongs to the ABC transporter superfamily
GT391_RS07600	COG3501	Rhs element vgr protein
GT391_RS07610	COG3977	Valine--pyruvate aminotransferase
GT391_RS07645	COG3210	domain, Protein
GT391_RS07650	COG2831	hemolysin activation secretion protein
GT391_RS07655	COG0457	Tetratricopeptide repeat
GT391_RS07655	COG3118	belongs to the thioredoxin family
GT391_RS07660	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GT391_RS07670	COG1215	transferase activity, transferring glycosyl groups
GT391_RS07675	COG1192	Involved in chromosome partitioning
GT391_RS07695	COG2194	sulfuric ester hydrolase activity
GT391_RS07700	COG2199	diguanylate cyclase activity
GT391_RS07700	COG2200	EAL domain
GT391_RS07705	COG1301	dicarboxylic acid transport
GT391_RS07710	COG0612	Peptidase, M16
GT391_RS07715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT391_RS07720	COG1295	ribonuclease BN
GT391_RS07725	COG0477	Major facilitator Superfamily
GT391_RS07735	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GT391_RS07740	COG0425	Belongs to the sulfur carrier protein TusA family
GT391_RS07750	COG3714	YhhN family
GT391_RS07765	COG3776	membrane
GT391_RS07770	COG0742	ribosomal rna small subunit methyltransferase
GT391_RS07775	COG0552	protein localization to endoplasmic reticulum
GT391_RS07780	COG2884	Cell division ATP-binding protein ftsE
GT391_RS07785	COG2177	Part of the ABC transporter FtsEX involved in
GT391_RS07800	COG0683	leucine binding
GT391_RS07805	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT391_RS07810	COG4177	L-phenylalanine transmembrane transporter activity
GT391_RS07815	COG0411	ABC transporter
GT391_RS07820	COG0410	ABC transporter
GT391_RS07825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT391_RS07830	COG0840	transmembrane signaling receptor activity
GT391_RS07835	COG0840	transmembrane signaling receptor activity
GT391_RS07840	COG2610	gluconate transmembrane transporter activity
GT391_RS07845	COG3622	Belongs to the hyi family
GT391_RS07850	COG0235	Class ii aldolase
GT391_RS07855	COG3395	kinase activity
GT391_RS07860	COG2084	Dehydrogenase
GT391_RS07865	COG1349	DNA-binding transcription factor activity
GT391_RS07910	COG1653	transport
GT391_RS07915	COG1175	transmembrane transport
GT391_RS07920	COG0395	ABC-type sugar transport system, permease component
GT391_RS07925	COG3842	ATPase activity
GT391_RS07930	COG0584	glycerophosphoryl diester phosphodiesterase
GT391_RS07935	COG0679	Auxin Efflux Carrier
GT391_RS07945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GT391_RS07955	COG2271	Major facilitator Superfamily
GT391_RS07965	COG2197	response regulator
GT391_RS07980	COG2205	protein histidine kinase activity
GT391_RS07985	COG0745	RESPONSE REGULATOR receiver
GT391_RS07990	COG3678	ATP-independent chaperone mediated protein folding
GT391_RS07995	COG2814	Major facilitator Superfamily
GT391_RS08000	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GT391_RS08005	COG0205	6-phosphofructokinase activity
GT391_RS08010	COG0583	DNA-binding transcription factor activity
GT391_RS08050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT391_RS08055	COG1116	anion transmembrane transporter activity
GT391_RS08060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GT391_RS08065	COG2957	Belongs to the agmatine deiminase family
GT391_RS08070	COG0149	triose-phosphate isomerase activity
GT391_RS08080	COG3152	Membrane
GT391_RS08090	COG1494	fructose-1,6-bisphosphatase
GT391_RS08100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GT391_RS08105	COG3074	FtsZ-dependent cytokinesis
GT391_RS08110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT391_RS08115	COG1575	Belongs to the MenA family. Type 1 subfamily
GT391_RS08120	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GT391_RS08125	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GT391_RS08130	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GT391_RS08135	COG1609	Transcriptional regulator
GT391_RS08140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GT391_RS08145	COG0254	rRNA binding
GT391_RS08150	COG1598	PFAM Uncharacterised protein family UPF0150
GT391_RS08160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT391_RS08170	COG1120	ATPase activity
GT391_RS08175	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
GT391_RS08180	COG0626	cystathionine gamma-synthase activity
GT391_RS08185	COG0527	aspartate kinase activity
GT391_RS08185	COG0460	homoserine dehydrogenase
GT391_RS08200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GT391_RS08205	COG1309	transcriptional regulator
GT391_RS08215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GT391_RS08220	COG4206	TonB-dependent receptor
GT391_RS08225	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GT391_RS08250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GT391_RS08255	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GT391_RS08255	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GT391_RS08260	COG1072	(Pantothenic acid kinase))
GT391_RS08295	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GT391_RS08300	COG0250	Participates in transcription elongation, termination and antitermination
GT391_RS08305	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GT391_RS08310	COG0081	regulation of translation
GT391_RS08315	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GT391_RS08320	COG0222	ribosome binding
GT391_RS08325	COG0085	RNA polymerase activity
GT391_RS08330	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GT391_RS08335	COG0477	Major facilitator Superfamily
GT391_RS08340	COG5457	Domain of unknown function (DUF1127)
GT391_RS08345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT391_RS08355	COG2022	thiamine diphosphate biosynthetic process
GT391_RS08360	COG2104	thiamine diphosphate biosynthetic process
GT391_RS08365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GT391_RS08370	COG0352	thiamine-phosphate diphosphorylase activity
GT391_RS08375	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GT391_RS08380	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GT391_RS08385	COG2816	NAD+ diphosphatase activity
GT391_RS08390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GT391_RS08395	COG1515	deoxyribonuclease V activity
GT391_RS08400	COG3068	Protein conserved in bacteria
GT391_RS08415	COG0151	Belongs to the GarS family
GT391_RS08420	COG0138	bifunctional purine biosynthesis protein purh
GT391_RS08460	COG1879	ABC-type sugar transport system periplasmic component
GT391_RS08465	COG1129	ABC transporter
GT391_RS08470	COG1172	Belongs to the binding-protein-dependent transport system permease family
GT391_RS08475	COG1172	Belongs to the binding-protein-dependent transport system permease family
GT391_RS08480	COG0583	DNA-binding transcription factor activity
GT391_RS08485	COG3085	chromosome segregation
GT391_RS08505	COG3978	acetolactate synthase activity
GT391_RS08510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GT391_RS08515	COG0129	dihydroxy-acid dehydratase activity
GT391_RS08535	COG0583	DNA-binding transcription factor activity
GT391_RS08540	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GT391_RS08550	COG0583	DNA-binding transcription factor activity
GT391_RS08560	COG0506	proline dehydrogenase activity
GT391_RS08560	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GT391_RS08560	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GT391_RS08565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT391_RS08570	COG0210	DNA helicase
GT391_RS08575	COG0248	Ppx GppA phosphatase
GT391_RS08580	COG0513	Belongs to the DEAD box helicase family
GT391_RS08585	COG3118	belongs to the thioredoxin family
GT391_RS08590	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GT391_RS08595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GT391_RS08600	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GT391_RS08605	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GT391_RS08610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GT391_RS08615	COG1088	dTDP-glucose 4,6-dehydratase activity
GT391_RS08620	COG0456	acetyltransferase
GT391_RS08625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GT391_RS08630	COG2244	polysaccharide biosynthetic process
GT391_RS08635	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GT391_RS08645	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GT391_RS08650	COG1113	amino acid transport
GT391_RS08680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GT391_RS08690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT391_RS08695	COG0765	amino acid transport
GT391_RS08700	COG1126	abc transporter atp-binding protein
GT391_RS08710	COG3071	HemY protein
GT391_RS08715	COG2959	enzyme of heme biosynthesis
GT391_RS08720	COG1587	Uroporphyrinogen-III synthase
GT391_RS08725	COG0181	hydroxymethylbilane synthase activity
GT391_RS08735	COG2814	Major facilitator Superfamily
GT391_RS08740	COG1965	Belongs to the frataxin family
GT391_RS08750	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GT391_RS08765	COG1011	Hydrolase
GT391_RS08770	COG0210	DNA helicase
GT391_RS08775	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GT391_RS08780	COG0598	Magnesium transport protein CorA
GT391_RS08785	COG3180	Ammonia monooxygenase
GT391_RS08795	COG2050	protein possibly involved in aromatic compounds catabolism
GT391_RS08805	COG0514	ATP-dependent DNA helicase (RecQ)
GT391_RS08810	COG1280	lysine exporter protein (LysE YggA)
GT391_RS08815	COG1280	lysine exporter protein (LysE YggA)
GT391_RS08820	COG2267	carboxylic ester hydrolase activity
GT391_RS08825	COG0561	phosphatase activity
GT391_RS08830	COG0584	glycerophosphoryl diester phosphodiesterase
GT391_RS08835	COG2271	Major facilitator Superfamily
GT391_RS08840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GT391_RS08845	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GT391_RS08850	COG0247	lactate metabolic process
GT391_RS08855	COG1741	Belongs to the pirin family
GT391_RS08860	COG1609	Transcriptional regulator
GT391_RS08865	COG3265	gluconokinase activity
GT391_RS08870	COG2610	gluconate transmembrane transporter activity
GT391_RS08875	COG2095	MarC family integral membrane protein
GT391_RS08880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GT391_RS08890	COG3275	phosphorelay sensor kinase activity
GT391_RS08895	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GT391_RS08900	COG1523	belongs to the glycosyl hydrolase 13 family
GT391_RS08905	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GT391_RS08910	COG0297	glycogen (starch) synthase activity
GT391_RS08915	COG0058	SHG alpha-glucan phosphorylase activity
GT391_RS08920	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GT391_RS08925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GT391_RS08930	COG0705	Rhomboid family
GT391_RS08935	COG1349	DNA-binding transcription factor activity
GT391_RS08940	COG0058	SHG alpha-glucan phosphorylase activity
GT391_RS08945	COG1640	4-alpha-glucanotransferase
GT391_RS08950	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GT391_RS08950	COG0316	Belongs to the HesB IscA family
GT391_RS08955	COG1040	competence protein
GT391_RS08960	COG2267	carboxylic ester hydrolase activity
GT391_RS08965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT391_RS08980	COG1785	Belongs to the alkaline phosphatase family
GT391_RS09030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GT391_RS09030	COG0515	serine threonine protein kinase
GT391_RS09060	COG1414	Transcriptional regulator
GT391_RS09065	COG2183	response to ionizing radiation
GT391_RS09075	COG0840	transmembrane signaling receptor activity
GT391_RS09085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GT391_RS09095	COG4264	IucA IucC family
GT391_RS09100	COG4774	siderophore transport
GT391_RS09105	COG0019	diaminopimelate decarboxylase activity
GT391_RS09110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GT391_RS09115	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GT391_RS09120	COG2814	Major facilitator Superfamily
GT391_RS09135	COG0745	RESPONSE REGULATOR receiver
GT391_RS09145	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GT391_RS09150	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GT391_RS09155	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GT391_RS09160	COG1011	Hydrolase
GT391_RS09170	COG0494	nUDIX hydrolase
GT391_RS09180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GT391_RS09205	COG4796	Type ii and iii secretion system protein
GT391_RS09210	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GT391_RS09215	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GT391_RS09230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GT391_RS09235	COG0546	phosphoglycolate phosphatase activity
GT391_RS09245	COG1473	amidohydrolase
GT391_RS09270	COG1648	precorrin-2 dehydrogenase activity
GT391_RS09270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GT391_RS09275	COG2146	nitrite reductase [NAD(P)H] activity
GT391_RS09280	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GT391_RS09285	COG4948	Mandelate Racemase Muconate Lactonizing
GT391_RS09290	COG0747	negative chemotaxis
GT391_RS09295	COG0601	transmembrane transport
GT391_RS09305	COG0444	Belongs to the ABC transporter superfamily
GT391_RS09310	COG4608	Belongs to the ABC transporter superfamily
GT391_RS09315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GT391_RS09335	COG3866	Pectate lyase
GT391_RS09355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT391_RS09360	COG1765	OsmC-like protein
GT391_RS09365	COG3954	Phosphoribulokinase
GT391_RS09370	COG3089	Belongs to the UPF0270 family
GT391_RS09375	COG0429	hydrolase of the alpha beta-hydrolase fold
GT391_RS09385	COG0488	(ABC) transporter
GT391_RS09390	COG2249	NAD(P)H dehydrogenase (quinone) activity
GT391_RS09395	COG0475	glutathione-regulated potassium exporter activity
GT391_RS09395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GT391_RS09400	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GT391_RS09405	COG1047	Peptidyl-prolyl cis-trans
GT391_RS09410	COG2900	Belongs to the SlyX family
GT391_RS09415	COG0545	Peptidyl-prolyl cis-trans isomerase
GT391_RS09430	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GT391_RS09435	COG0642	Histidine kinase
GT391_RS09440	COG0745	RESPONSE REGULATOR receiver
GT391_RS09450	COG2964	Protein conserved in bacteria
GT391_RS09455	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GT391_RS09460	COG2923	Belongs to the DsrF TusC family
GT391_RS09465	COG2168	tRNA wobble position uridine thiolation
GT391_RS09470	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GT391_RS09475	COG0049	tRNA binding
GT391_RS09480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GT391_RS09495	COG2193	ferroxidase activity
GT391_RS09500	COG0051	transcription antitermination factor activity, RNA binding
GT391_RS09505	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GT391_RS09510	COG0088	Forms part of the polypeptide exit tunnel
GT391_RS09520	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GT391_RS09525	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GT391_RS09530	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GT391_RS09535	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GT391_RS09540	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GT391_RS09545	COG0255	Belongs to the universal ribosomal protein uL29 family
GT391_RS09550	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GT391_RS09555	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GT391_RS09560	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GT391_RS09565	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GT391_RS09570	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GT391_RS09575	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GT391_RS09580	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GT391_RS09585	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GT391_RS09590	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GT391_RS09595	COG1841	ribosomal large subunit assembly
GT391_RS09600	COG0200	Binds to the 23S rRNA
GT391_RS09605	COG0201	protein transport
GT391_RS09610	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GT391_RS09615	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GT391_RS09625	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GT391_RS09630	COG0202	RNA polymerase activity
GT391_RS09635	COG0203	ribosomal protein L17
GT391_RS09640	COG3036	rescue of stalled ribosome
GT391_RS09645	COG1970	mechanosensitive ion channel activity
GT391_RS09650	COG0569	domain protein
GT391_RS09655	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GT391_RS09655	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GT391_RS09660	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GT391_RS09665	COG0242	peptide deformylase activity
GT391_RS09670	COG0758	DNA mediated transformation
GT391_RS09675	COG2922	Belongs to the Smg family
GT391_RS09680	COG0551	DNA topoisomerase type I activity
GT391_RS09685	COG0009	L-threonylcarbamoyladenylate synthase
GT391_RS09690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GT391_RS09700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GT391_RS09725	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GT391_RS09730	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GT391_RS09740	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GT391_RS09750	COG1410	methionine synthase
GT391_RS09750	COG0646	methionine synthase
GT391_RS09760	COG4977	sequence-specific DNA binding
GT391_RS09760	COG1917	Cupin 2, conserved barrel domain protein
GT391_RS09770	COG0471	metal ion transport
GT391_RS09780	COG0527	aspartate kinase activity
GT391_RS09785	COG0166	Belongs to the GPI family
GT391_RS09795	COG1509	lysine 2,3-aminomutase activity
GT391_RS09800	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GT391_RS09815	COG3040	lipid binding
GT391_RS09820	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GT391_RS09825	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GT391_RS09830	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GT391_RS09835	COG1053	succinate dehydrogenase
GT391_RS09840	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GT391_RS09845	COG1511	domain protein
GT391_RS09845	COG3264	Mechanosensitive ion channel
GT391_RS09850	COG0688	phosphatidylethanolamine metabolic process
GT391_RS09855	COG1162	GTPase activity
GT391_RS09860	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GT391_RS09925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT391_RS09930	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GT391_RS09950	COG1064	alcohol dehydrogenase
GT391_RS09955	COG1704	LemA family
GT391_RS09985	COG0582	viral genome integration into host DNA
GT391_RS10000	COG3423	Transcriptional regulator
GT391_RS10035	COG1136	(ABC) transporter
GT391_RS10040	COG0577	efflux transmembrane transporter activity
GT391_RS10040	COG1136	(ABC) transporter
GT391_RS10065	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GT391_RS10070	COG0450	alkyl hydroperoxide reductase
GT391_RS10080	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GT391_RS10085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GT391_RS10085	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GT391_RS10090	COG0802	atpase or kinase
GT391_RS10100	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GT391_RS10105	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GT391_RS10110	COG1923	regulation of RNA biosynthetic process
GT391_RS10115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GT391_RS10120	COG0330	HflC and HflK could
GT391_RS10125	COG0330	HflC and HflK could
GT391_RS10130	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GT391_RS10135	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GT391_RS10140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GT391_RS10145	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GT391_RS10150	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GT391_RS10155	COG1678	Uncharacterized ACR, COG1678
GT391_RS10160	COG0189	ligase activity
GT391_RS10165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GT391_RS10170	COG2356	endonuclease I
GT391_RS10175	COG3091	SprT-like family
GT391_RS10180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GT391_RS10185	COG1166	arginine decarboxylase activity
GT391_RS10195	COG0501	Belongs to the peptidase M48B family
GT391_RS10200	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GT391_RS10205	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GT391_RS10210	COG0126	phosphoglycerate kinase activity
GT391_RS10215	COG0191	fructose-bisphosphate aldolase activity
GT391_RS10220	COG0668	transmembrane transport
GT391_RS10225	COG1279	arginine transmembrane transporter activity
GT391_RS10235	COG0583	DNA-binding transcription factor activity
GT391_RS10240	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GT391_RS10245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT391_RS10250	COG0604	alcohol dehydrogenase
GT391_RS10255	COG0583	DNA-binding transcription factor activity
GT391_RS10260	COG0840	transmembrane signaling receptor activity
GT391_RS10265	COG0488	(ABC) transporter
GT391_RS10275	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GT391_RS10280	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GT391_RS10290	COG2207	Transcriptional regulator
GT391_RS10290	COG3708	Transcriptional regulator
GT391_RS10295	COG3045	CreA protein
GT391_RS10300	COG0745	RESPONSE REGULATOR receiver
GT391_RS10305	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GT391_RS10320	COG0083	homoserine kinase activity
GT391_RS10330	COG3022	response to hydroperoxide
GT391_RS10335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GT391_RS10340	COG0745	RESPONSE REGULATOR receiver
GT391_RS10340	COG3706	GGDEF domain
GT391_RS10345	COG0521	Mo-molybdopterin cofactor biosynthetic process
GT391_RS10355	COG1584	GPR1 FUN34 yaaH family protein
GT391_RS10360	COG0443	Heat shock 70 kDa protein
GT391_RS10365	COG0484	heat shock protein binding
GT391_RS10370	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GT391_RS10375	COG0583	DNA-binding transcription factor activity
GT391_RS10380	COG0268	Binds directly to 16S ribosomal RNA
GT391_RS10385	COG0196	riboflavin kinase activity
GT391_RS10390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GT391_RS10395	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GT391_RS10400	COG1047	Peptidyl-prolyl cis-trans
GT391_RS10405	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GT391_RS10410	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GT391_RS10415	COG0505	Belongs to the CarA family
GT391_RS10420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GT391_RS10425	COG1827	regulation of RNA biosynthetic process
GT391_RS10440	COG2966	Psort location CytoplasmicMembrane, score
GT391_RS10445	COG3610	response to peptide
GT391_RS10450	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GT391_RS10470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GT391_RS10475	COG2967	ApaG domain
GT391_RS10480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GT391_RS10485	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GT391_RS10490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT391_RS10495	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GT391_RS10500	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GT391_RS10505	COG0564	pseudouridine synthase activity
GT391_RS10510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GT391_RS10515	COG0417	DNA replication proofreading
GT391_RS10520	COG3706	GGDEF domain
GT391_RS10525	COG0586	Pfam SNARE associated Golgi protein
GT391_RS10530	COG0440	acetolactate synthase activity
GT391_RS10535	COG0028	Belongs to the TPP enzyme family
GT391_RS10540	COG3507	Belongs to the glycosyl hydrolase 43 family
GT391_RS10545	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GT391_RS10550	COG1178	ABC-type Fe3 transport system permease component
GT391_RS10555	COG4143	(ABC) transporter
GT391_RS10570	COG4533	DNA binding
GT391_RS10590	COG0840	transmembrane signaling receptor activity
GT391_RS10610	COG0066	3-isopropylmalate dehydratase activity
GT391_RS10615	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT391_RS10620	COG0473	3-isopropylmalate dehydrogenase activity
GT391_RS10625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GT391_RS10630	COG1022	Amp-dependent synthetase and ligase
GT391_RS10635	COG0028	Belongs to the TPP enzyme family
GT391_RS10645	COG1609	Transcriptional regulator
GT391_RS10655	COG2001	Belongs to the MraZ family
GT391_RS10660	COG0275	rRNA processing
GT391_RS10665	COG3116	cell division
GT391_RS10670	COG0768	penicillin binding
GT391_RS10675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GT391_RS10680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GT391_RS10685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GT391_RS10690	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GT391_RS10695	COG0772	Belongs to the SEDS family
GT391_RS10700	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GT391_RS10705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GT391_RS10710	COG1181	Belongs to the D-alanine--D-alanine ligase family
GT391_RS10715	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GT391_RS10720	COG0849	cell division
GT391_RS10725	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GT391_RS10730	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GT391_RS10745	COG0653	protein targeting
GT391_RS10750	COG0494	nUDIX hydrolase
GT391_RS10755	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GT391_RS10760	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GT391_RS10765	COG0237	dephospho-CoA kinase activity
GT391_RS10770	COG0516	GMP reductase activity
GT391_RS10775	COG1459	type II secretion system
GT391_RS10780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GT391_RS10785	COG4969	Belongs to the N-Me-Phe pilin family
GT391_RS10790	COG0157	Belongs to the NadC ModD family
GT391_RS10795	COG3248	Nucleoside-binding outer membrane protein
GT391_RS10800	COG3023	N-Acetylmuramoyl-L-alanine amidase
GT391_RS10805	COG3725	Membrane protein required for beta-lactamase induction
GT391_RS10810	COG3940	Belongs to the glycosyl hydrolase 43 family
GT391_RS10815	COG2211	Major facilitator Superfamily
GT391_RS10820	COG1113	amino acid transport
GT391_RS10825	COG2186	Transcriptional regulator
GT391_RS10830	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GT391_RS10835	COG0508	dehydrogenase complex catalyzes the overall conversion of
GT391_RS10840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GT391_RS10845	COG0583	DNA-binding transcription factor activity
GT391_RS10865	COG1073	alpha beta
GT391_RS10875	COG2079	MmgE PrpD family protein
GT391_RS10890	COG0640	Transcriptional regulator
GT391_RS10910	COG3112	Uncharacterised protein family (UPF0231)
GT391_RS10915	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GT391_RS10930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT391_RS10935	COG1609	Transcriptional regulator
GT391_RS10945	COG1028	Short-chain dehydrogenase reductase Sdr
GT391_RS10950	COG2731	YhcH YjgK YiaL family protein
GT391_RS10965	COG2271	Major facilitator Superfamily
GT391_RS10970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT391_RS10975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT391_RS10980	COG1454	alcohol dehydrogenase
GT391_RS10985	COG3395	kinase activity
GT391_RS10990	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GT391_RS10995	COG1349	DNA-binding transcription factor activity
GT391_RS11005	COG0803	Belongs to the bacterial solute-binding protein 9 family
GT391_RS11010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GT391_RS11015	COG1121	(ABC) transporter
GT391_RS11025	COG2971	BadF BadG BcrA BcrD
GT391_RS11045	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GT391_RS11055	COG1175	transmembrane transport
GT391_RS11060	COG0395	ABC-type sugar transport system, permease component
GT391_RS11090	COG2211	Major facilitator Superfamily
GT391_RS11105	COG0629	single-stranded DNA binding
GT391_RS11110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GT391_RS11140	COG1203	CRISPR-associated helicase, Cas3
GT391_RS11145	COG1518	maintenance of DNA repeat elements
GT391_RS11175	COG1451	nucleotide metabolic process
GT391_RS11180	COG1448	Aminotransferase
GT391_RS11190	COG1522	sequence-specific DNA binding
GT391_RS11200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GT391_RS11205	COG0305	Participates in initiation and elongation during chromosome replication
GT391_RS11215	COG2124	cytochrome p450
GT391_RS11230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GT391_RS11270	COG0583	DNA-binding transcription factor activity
GT391_RS11275	COG0019	diaminopimelate decarboxylase activity
GT391_RS11290	COG1609	Transcriptional regulator
GT391_RS11295	COG1447	Phosphotransferase system cellobiose-specific component IIA
GT391_RS11300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GT391_RS11305	COG2723	6-phospho-beta-galactosidase activity
GT391_RS11310	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GT391_RS11315	COG2186	Transcriptional regulator
GT391_RS11325	COG0204	Acyl-transferase
GT391_RS11325	COG0318	PFAM AMP-dependent synthetase and ligase
GT391_RS11330	COG0477	Major facilitator Superfamily
GT391_RS11335	COG2153	protein acetylation
GT391_RS11360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GT391_RS11365	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GT391_RS11370	COG1872	DUF167
GT391_RS11375	COG0762	integral membrane protein
GT391_RS11380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GT391_RS11385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GT391_RS11390	COG2805	Type II/IV secretion system protein
GT391_RS11395	COG3706	GGDEF domain
GT391_RS11400	COG0840	transmembrane signaling receptor activity
GT391_RS11405	COG1959	2 iron, 2 sulfur cluster binding
GT391_RS11410	COG0557	exoribonuclease II activity
GT391_RS11415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GT391_RS11425	COG3766	membrane
GT391_RS11435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GT391_RS11440	COG1690	Belongs to the RtcB family
GT391_RS11445	COG0840	transmembrane signaling receptor activity
GT391_RS11450	COG1073	alpha beta
GT391_RS11455	COG0360	Binds together with S18 to 16S ribosomal RNA
GT391_RS11460	COG2965	DNA replication, synthesis of RNA primer
GT391_RS11465	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GT391_RS11470	COG0359	binds to the 23S rRNA
GT391_RS11480	COG3061	Opacity-associated protein A
GT391_RS11485	COG0545	Peptidyl-prolyl cis-trans isomerase
GT391_RS11490	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GT391_RS11495	COG3961	Belongs to the TPP enzyme family
GT391_RS11510	COG1733	regulation of RNA biosynthetic process
GT391_RS11515	COG0737	Belongs to the 5'-nucleotidase family
GT391_RS11520	COG1218	3'(2'),5'-bisphosphate nucleotidase
GT391_RS11525	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GT391_RS11535	COG1253	flavin adenine dinucleotide binding
GT391_RS11540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT391_RS11545	COG0729	surface antigen
GT391_RS11550	COG2911	Protein conserved in bacteria
GT391_RS11555	COG2105	PFAM AIG2 family protein
GT391_RS11560	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GT391_RS11565	COG0840	transmembrane signaling receptor activity
GT391_RS11570	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GT391_RS11575	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GT391_RS11580	COG1968	undecaprenyl-diphosphatase activity
GT391_RS11585	COG0617	tRNA 3'-terminal CCA addition
GT391_RS11590	COG4991	sh3 domain protein
GT391_RS11595	COG3025	triphosphatase activity
GT391_RS11600	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GT391_RS11605	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GT391_RS11605	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GT391_RS11610	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GT391_RS11615	COG3530	Putative quorum-sensing-regulated virulence factor
GT391_RS11630	COG0840	transmembrane signaling receptor activity
GT391_RS11635	COG2721	sulfolactate sulfo-lyase activity
GT391_RS11640	COG2271	Major facilitator Superfamily
GT391_RS11645	COG4948	Mandelate Racemase Muconate Lactonizing
GT391_RS11650	COG4948	Mandelate Racemase Muconate Lactonizing
GT391_RS11660	COG2084	Dehydrogenase
GT391_RS11665	COG1929	Belongs to the glycerate kinase type-1 family
GT391_RS11680	COG3302	dmso reductase anchor subunit
GT391_RS11685	COG0437	4 iron, 4 sulfur cluster binding
GT391_RS11690	COG0243	molybdopterin cofactor binding
GT391_RS11700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GT391_RS11705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GT391_RS11710	COG3956	TIGRFAM MazG family protein
GT391_RS11715	COG0504	CTP synthase activity
GT391_RS11720	COG0148	phosphopyruvate hydratase activity
GT391_RS11745	COG0583	DNA-binding transcription factor activity
GT391_RS11755	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GT391_RS11760	COG1028	Short-chain dehydrogenase reductase Sdr
GT391_RS11765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GT391_RS11770	COG0602	queuosine metabolic process
GT391_RS11775	COG0720	synthase
GT391_RS11795	COG2200	EAL domain
GT391_RS11805	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GT391_RS11810	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GT391_RS11815	COG0175	sulfate reduction
GT391_RS11825	COG1064	alcohol dehydrogenase
GT391_RS11830	COG2207	Transcriptional regulator
GT391_RS11840	COG1648	precorrin-2 dehydrogenase activity
GT391_RS11840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GT391_RS11845	COG0175	sulfate reduction
GT391_RS11850	COG2895	sulfate adenylyltransferase (ATP) activity
GT391_RS11865	COG1126	abc transporter atp-binding protein
GT391_RS11870	COG0765	amino acid transport
GT391_RS11880	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GT391_RS11885	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GT391_RS11890	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GT391_RS11895	COG0585	pseudouridine synthase activity
GT391_RS11900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GT391_RS11905	COG1388	LysM domain
GT391_RS11905	COG4942	peptidase
GT391_RS11910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GT391_RS11915	COG0442	prolyl-tRNA aminoacylation
GT391_RS11920	COG1720	tRNA m6t6A37 methyltransferase activity
GT391_RS11930	COG1464	Belongs to the NlpA lipoprotein family
GT391_RS11935	COG2011	ABC-type metal ion transport system permease component
GT391_RS11940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GT391_RS11945	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GT391_RS11980	COG0477	Major facilitator Superfamily
GT391_RS11985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT391_RS11990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GT391_RS11990	COG0045	succinate-CoA ligase (ADP-forming) activity
GT391_RS11990	COG1042	CoA-binding domain protein
GT391_RS12000	COG3118	belongs to the thioredoxin family
GT391_RS12005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GT391_RS12015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GT391_RS12020	COG2814	Major facilitator Superfamily
GT391_RS12025	COG1566	PFAM secretion protein HlyD family protein
GT391_RS12030	COG1846	Transcriptional regulator
GT391_RS12040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GT391_RS12045	COG2814	Major facilitator Superfamily
GT391_RS12055	COG2113	Glycine betaine
GT391_RS12060	COG4176	ABC-type proline glycine betaine transport system permease component
GT391_RS12065	COG4175	Glycine betaine
GT391_RS12120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GT391_RS12135	COG0436	Aminotransferase
GT391_RS12140	COG0235	Class ii aldolase
GT391_RS12145	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
GT391_RS12150	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GT391_RS12155	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GT391_RS12160	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GT391_RS12165	COG1403	HNH endonuclease
GT391_RS12170	COG1960	acyl-CoA dehydrogenase activity
GT391_RS12175	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GT391_RS12180	COG0121	glutamine amidotransferase
GT391_RS12185	COG3034	peptidoglycan biosynthetic process
GT391_RS12190	COG2226	methyltransferase
GT391_RS12200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GT391_RS12205	COG2195	Cleaves the N-terminal amino acid of tripeptides
GT391_RS12210	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GT391_RS12240	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GT391_RS12245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GT391_RS12260	COG0464	growth
GT391_RS12325	COG2204	response regulator
GT391_RS12360	COG3501	Rhs element vgr protein
GT391_RS12420	COG2999	glutathione oxidoreductase activity
GT391_RS12430	COG0745	RESPONSE REGULATOR receiver
GT391_RS12430	COG3706	GGDEF domain
GT391_RS12450	COG1546	Belongs to the CinA family
GT391_RS12455	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GT391_RS12460	COG2137	regulation of response to DNA damage stimulus
GT391_RS12465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GT391_RS12470	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GT391_RS12495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT391_RS12500	COG1238	metal cluster binding
GT391_RS12505	COG2918	glutathione biosynthetic process
GT391_RS12510	COG1854	S-ribosylhomocysteine lyase activity
GT391_RS12515	COG4137	Cytochrome C assembly protein
GT391_RS12520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GT391_RS12525	COG0228	four-way junction DNA binding
GT391_RS12530	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GT391_RS12535	COG0336	Belongs to the RNA methyltransferase TrmD family
GT391_RS12540	COG0335	large ribosomal subunit rRNA binding
GT391_RS12545	COG2264	protein methyltransferase activity
GT391_RS12555	COG3279	Response regulator of the LytR AlgR family
GT391_RS12560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GT391_RS12565	COG0287	Prephenate dehydrogenase
GT391_RS12565	COG1605	Chorismate mutase
GT391_RS12570	COG0077	Prephenate dehydratase
GT391_RS12570	COG1605	Chorismate mutase
GT391_RS12575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GT391_RS12580	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT391_RS12585	COG0564	pseudouridine synthase activity
GT391_RS12595	COG0542	response to heat
GT391_RS12630	COG3021	interspecies interaction between organisms
GT391_RS12635	COG0741	lytic transglycosylase activity
GT391_RS12635	COG1388	LysM domain
GT391_RS12640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GT391_RS12645	COG2226	methyltransferase
GT391_RS12650	COG0328	RNA-DNA hybrid ribonuclease activity
GT391_RS12655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GT391_RS12665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GT391_RS12675	COG1780	Probably involved in ribonucleotide reductase function
GT391_RS12680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GT391_RS12685	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GT391_RS12690	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GT391_RS12705	COG3842	ATPase activity
GT391_RS12720	COG0288	reversible hydration of carbon dioxide
GT391_RS12725	COG1131	(ABC) transporter
GT391_RS12730	COG0842	Transport permease protein
GT391_RS12735	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GT391_RS12740	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GT391_RS12745	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GT391_RS12750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GT391_RS12760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GT391_RS12765	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GT391_RS12770	COG1489	DNA binding
GT391_RS12775	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GT391_RS12780	COG1643	Atp-dependent helicase
GT391_RS12785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GT391_RS12790	COG1120	ATPase activity
GT391_RS12795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GT391_RS12800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT391_RS12810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT391_RS12815	COG0625	glutathione transferase activity
GT391_RS12820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GT391_RS12825	COG0316	Belongs to the HesB IscA family
GT391_RS12835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GT391_RS12840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GT391_RS12845	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GT391_RS12850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GT391_RS12855	COG3835	regulator
GT391_RS12860	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GT391_RS12870	COG4208	sulfate ABC transporter
GT391_RS12875	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GT391_RS12885	COG1902	pentaerythritol trinitrate reductase activity
GT391_RS12910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GT391_RS12915	COG2819	hydrolase of the alpha beta superfamily
GT391_RS12930	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GT391_RS12935	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GT391_RS12940	COG0513	Belongs to the DEAD box helicase family
GT391_RS12945	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GT391_RS12950	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GT391_RS12965	COG3026	antisigma factor binding
GT391_RS12970	COG3086	response to oxidative stress
GT391_RS12975	COG0481	GTPase activity
GT391_RS12980	COG0681	Belongs to the peptidase S26 family
GT391_RS12985	COG0571	ribonuclease III activity
GT391_RS12990	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GT391_RS12995	COG1381	Involved in DNA repair and RecF pathway recombination
GT391_RS13000	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GT391_RS13005	COG0736	holo-[acyl-carrier-protein] synthase activity
GT391_RS13010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GT391_RS13015	COG2200	EAL domain
GT391_RS13025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT391_RS13030	COG2274	protein secretion by the type I secretion system
GT391_RS13050	COG3287	FIST C domain
GT391_RS13050	COG2199	diguanylate cyclase activity
GT391_RS13050	COG2200	EAL domain
GT391_RS13060	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GT391_RS13065	COG0560	Phosphoserine phosphatase
GT391_RS13070	COG0590	tRNA wobble adenosine to inosine editing
GT391_RS13075	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GT391_RS13080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GT391_RS13080	COG0047	phosphoribosylformylglycinamidine synthase activity
GT391_RS13085	COG2205	protein histidine kinase activity
GT391_RS13090	COG3170	Tfp pilus assembly protein FimV
GT391_RS13095	COG2204	response regulator
GT391_RS13100	COG0347	Belongs to the P(II) protein family
GT391_RS13105	COG4677	pectinesterase activity
GT391_RS13115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GT391_RS13115	COG1017	nitric oxide dioxygenase activity
GT391_RS13120	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GT391_RS13130	COG2814	Major facilitator Superfamily
GT391_RS13135	COG3683	transport system, periplasmic component
GT391_RS13140	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GT391_RS13150	COG0840	transmembrane signaling receptor activity
GT391_RS13165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT391_RS13175	COG0483	inositol monophosphate 1-phosphatase activity
GT391_RS13180	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GT391_RS13185	COG1959	2 iron, 2 sulfur cluster binding
GT391_RS13190	COG1104	cysteine desulfurase activity
GT391_RS13195	COG0822	iron-sulfur transferase activity
GT391_RS13200	COG0316	Belongs to the HesB IscA family
GT391_RS13205	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GT391_RS13210	COG0443	Heat shock 70 kDa protein
GT391_RS13215	COG0633	Ferredoxin
GT391_RS13220	COG2975	iron-sulfur cluster assembly
GT391_RS13225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GT391_RS13235	COG1737	Transcriptional regulator
GT391_RS13240	COG2897	thiosulfate sulfurtransferase activity
GT391_RS13245	COG1486	melibiose metabolic process
GT391_RS13250	COG2190	(PTS) system
GT391_RS13250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT391_RS13250	COG1263	PTS System
GT391_RS13255	COG0105	UTP biosynthetic process
GT391_RS13260	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GT391_RS13270	COG1426	Protein conserved in bacteria
GT391_RS13275	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GT391_RS13280	COG0124	histidyl-tRNA synthetase
GT391_RS13285	COG2976	Protein conserved in bacteria
GT391_RS13290	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT391_RS13295	COG1160	GTP binding
GT391_RS13310	COG1645	bacterial-type flagellum-dependent swarming motility
GT391_RS13325	COG1570	exodeoxyribonuclease VII activity
GT391_RS13330	COG0517	IMP dehydrogenase activity
GT391_RS13330	COG0516	GMP reductase activity
GT391_RS13335	COG0519	Catalyzes the synthesis of GMP from XMP
GT391_RS13335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GT391_RS13340	COG0667	Aldo Keto reductase
GT391_RS13365	COG3423	Transcriptional regulator
GT391_RS13420	COG3706	GGDEF domain
GT391_RS13425	COG1064	alcohol dehydrogenase
GT391_RS13430	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GT391_RS13435	COG0351	phosphomethylpyrimidine kinase
GT391_RS13440	COG3223	Belongs to the PsiE family
GT391_RS13445	COG1597	lipid kinase activity
GT391_RS13455	COG0435	Glutathione S-transferase
GT391_RS13470	COG0745	RESPONSE REGULATOR receiver
GT391_RS13475	COG2205	protein histidine kinase activity
GT391_RS13480	COG0477	Major facilitator Superfamily
GT391_RS13485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT391_RS13490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT391_RS13495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT391_RS13500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GT391_RS13510	COG0277	FAD linked oxidase domain protein
GT391_RS13520	COG1874	Beta-galactosidase
GT391_RS13525	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GT391_RS13530	COG3833	ABC-type maltose transport systems, permease component
GT391_RS13535	COG1175	transmembrane transport
GT391_RS13540	COG2182	Extracellular solute-binding protein
GT391_RS13545	COG3842	ATPase activity
GT391_RS13555	COG4580	involved in the transport of maltose and maltodextrins
GT391_RS13560	COG1609	Transcriptional regulator
GT391_RS13570	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GT391_RS13575	COG2239	Acts as a magnesium transporter
GT391_RS13580	COG1846	Transcriptional regulator
GT391_RS13585	COG1764	response to oxidative stress
GT391_RS13595	COG4804	nuclease activity
GT391_RS13630	COG5489	Protein of unknown function (DUF736)
GT391_RS13640	COG1396	sequence-specific DNA binding
GT391_RS13670	COG1192	Involved in chromosome partitioning
GT391_RS13685	COG4959	Type IV secretory pathway protease TraF
GT391_RS13695	COG0583	DNA-binding transcription factor activity
GT391_RS13705	COG2814	Major facilitator Superfamily
GT391_RS13715	COG0738	Major facilitator superfamily
GT391_RS13730	COG0583	DNA-binding transcription factor activity
GT391_RS13755	COG4962	Type ii secretion system protein e
GT391_RS13760	COG3838	Conjugal transfer protein Trbc
GT391_RS13770	COG3451	type IV secretory pathway VirB4
GT391_RS13785	COG3846	protein secretion by the type IV secretion system
GT391_RS13820	COG0248	Ppx GppA phosphatase
GT391_RS13825	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GT391_RS13830	COG0573	inorganic phosphate transmembrane transporter activity
GT391_RS13835	COG0581	inorganic phosphate transmembrane transporter activity
GT391_RS13840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GT391_RS13850	COG1760	l-serine dehydratase
GT391_RS13855	COG0814	amino acid
GT391_RS13860	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GT391_RS13865	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GT391_RS13870	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT391_RS13875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GT391_RS13885	COG0215	cysteine-tRNA ligase activity
GT391_RS13890	COG2501	S4 domain
GT391_RS13895	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GT391_RS13900	COG3706	GGDEF domain
GT391_RS13900	COG5001	Diguanylate cyclase
GT391_RS13900	COG2203	Gaf domain
GT391_RS13900	COG4251	negative regulation of phosphorylation
GT391_RS13905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GT391_RS13910	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GT391_RS13915	COG0463	Glycosyl transferase, family 2
GT391_RS13920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GT391_RS13920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT391_RS13925	COG0726	polysaccharide deacetylase
GT391_RS13930	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GT391_RS13935	COG2076	Multidrug Resistance protein
GT391_RS13940	COG2076	Multidrug Resistance protein
GT391_RS13945	COG3842	ATPase activity
GT391_RS13960	COG1447	Phosphotransferase system cellobiose-specific component IIA
GT391_RS13990	COG1696	Membrane protein involved in D-alanine export
GT391_RS13995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GT391_RS14010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GT391_RS14045	COG0582	viral genome integration into host DNA
GT391_RS14055	COG1511	domain protein
GT391_RS14055	COG3264	Mechanosensitive ion channel
GT391_RS14065	COG4948	Mandelate Racemase Muconate Lactonizing
GT391_RS14070	COG0436	Aminotransferase
GT391_RS14080	COG3266	domain, Protein
GT391_RS14085	COG3866	Pectate lyase
GT391_RS14165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT391_RS14190	COG0513	Belongs to the DEAD box helicase family
GT391_RS14230	COG2814	Major facilitator Superfamily
GT391_RS14235	COG1522	sequence-specific DNA binding
GT391_RS14260	COG2116	formate transmembrane transporter activity
GT391_RS14270	COG0579	oxidoreductase
GT391_RS14280	COG2067	long-chain fatty acid transport protein
GT391_RS14285	COG3691	Protein conserved in bacteria
GT391_RS14290	COG4106	trans-aconitate 2-methyltransferase activity
GT391_RS14300	COG0183	Belongs to the thiolase family
GT391_RS14305	COG1024	Enoyl-CoA hydratase
GT391_RS14305	COG1250	3-hydroxyacyl-CoA dehydrogenase
GT391_RS14315	COG3188	usher protein
GT391_RS14335	COG2062	phosphohistidine phosphatase, SixA
GT391_RS14340	COG2840	Smr protein MutS2
GT391_RS14345	COG2890	protein-(glutamine-N5) methyltransferase activity
GT391_RS14350	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GT391_RS14355	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
GT391_RS14360	COG0730	response to heat
GT391_RS14365	COG3101	peptidyl-lysine hydroxylation
GT391_RS14375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT391_RS14375	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GT391_RS14380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GT391_RS14390	COG0697	spore germination
GT391_RS14395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT391_RS14400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GT391_RS14405	COG0101	tRNA pseudouridine synthase activity
GT391_RS14410	COG0586	Pfam SNARE associated Golgi protein
GT391_RS14420	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GT391_RS14425	COG0285	dihydrofolate synthase activity
GT391_RS14430	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GT391_RS14435	COG1286	toxin biosynthetic process
GT391_RS14440	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GT391_RS14445	COG0163	prenyltransferase activity
GT391_RS14455	COG4215	(ABC) transporter
GT391_RS14460	COG4160	amino acid transport
GT391_RS14465	COG4598	ABC transporter
GT391_RS14470	COG1090	epimerase
GT391_RS14475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GT391_RS14480	COG0625	glutathione transferase activity
GT391_RS14485	COG0622	Phosphoesterase
GT391_RS14490	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GT391_RS14495	COG3739	integral membrane protein
GT391_RS14500	COG0280	phosphate acetyltransferase
GT391_RS14500	COG0857	belongs to the CobB CobQ family
GT391_RS14505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GT391_RS14510	COG3092	negative regulation of chromosome organization
GT391_RS14515	COG3013	Belongs to the UPF0304 family
GT391_RS14520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT391_RS14525	COG0490	domain, Protein
GT391_RS14525	COG0471	metal ion transport
GT391_RS14530	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GT391_RS14535	COG0436	Aminotransferase
GT391_RS14540	COG0583	DNA-binding transcription factor activity
GT391_RS14550	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT391_RS14555	COG0649	NAD binding
GT391_RS14555	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT391_RS14560	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GT391_RS14570	COG1034	ATP synthesis coupled electron transport
GT391_RS14575	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GT391_RS14580	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT391_RS14585	COG0839	Belongs to the complex I subunit 6 family
GT391_RS14590	COG0713	ATP synthesis coupled electron transport
GT391_RS14595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GT391_RS14600	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT391_RS14605	COG1007	ATP synthesis coupled electron transport
GT391_RS14610	COG4575	ribosome binding
GT391_RS14615	COG0366	Alpha amylase catalytic
GT391_RS14620	COG1263	PTS System
GT391_RS14620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT391_RS14635	COG0488	(ABC) transporter
GT391_RS14645	COG4771	TonB-dependent receptor
GT391_RS14670	COG0519	Catalyzes the synthesis of GMP from XMP
GT391_RS14670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GT391_RS14675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT391_RS14680	COG3058	Necessary for formate dehydrogenase activity
GT391_RS14690	COG2149	membrane
GT391_RS14695	COG4890	Cyd operon protein YbgT
GT391_RS14700	COG1294	oxidase, subunit
GT391_RS14705	COG1271	oxidase subunit
GT391_RS14715	COG3707	response regulator
GT391_RS14720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GT391_RS14730	COG1116	anion transmembrane transporter activity
GT391_RS14735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GT391_RS14735	COG2146	nitrite reductase [NAD(P)H] activity
GT391_RS14740	COG0243	molybdopterin cofactor binding
GT391_RS14745	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GT391_RS14745	COG1648	precorrin-2 dehydrogenase activity
GT391_RS14755	COG4807	Protein conserved in bacteria
GT391_RS14760	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GT391_RS14770	COG1129	ABC transporter
GT391_RS14775	COG1172	Belongs to the binding-protein-dependent transport system permease family
GT391_RS14780	COG1172	Belongs to the binding-protein-dependent transport system permease family
GT391_RS14790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT391_RS14795	COG1070	Carbohydrate kinase
GT391_RS14800	COG0640	Transcriptional regulator
GT391_RS14805	COG1902	pentaerythritol trinitrate reductase activity
GT391_RS14810	COG4977	sequence-specific DNA binding
GT391_RS14815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT391_RS14820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT391_RS14825	COG0745	RESPONSE REGULATOR receiver
GT391_RS14830	COG2205	protein histidine kinase activity
GT391_RS14855	COG0583	DNA-binding transcription factor activity
GT391_RS14875	COG0765	amino acid transport
GT391_RS14880	COG0765	amino acid transport
GT391_RS14895	COG4948	Mandelate Racemase Muconate Lactonizing
GT391_RS14905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT391_RS14920	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GT391_RS14925	COG3842	ATPase activity
GT391_RS14930	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT391_RS14945	COG0747	negative chemotaxis
GT391_RS14950	COG0601	transmembrane transport
GT391_RS14960	COG0444	Belongs to the ABC transporter superfamily
GT391_RS14965	COG4172	Belongs to the ABC transporter superfamily
GT391_RS14970	COG0659	secondary active sulfate transmembrane transporter activity
GT391_RS14975	COG0481	GTPase activity
GT391_RS14980	COG0300	oxidoreductase activity
GT391_RS15000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT391_RS15005	COG2814	Major facilitator Superfamily
GT391_RS15035	COG2205	protein histidine kinase activity
GT391_RS15040	COG4227	nucleotidyltransferase activity
GT391_RS15085	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
GT391_RS15095	COG3504	Conjugal transfer protein
GT391_RS15150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GT391_RS15170	COG3423	Transcriptional regulator
GT391_RS15185	COG0582	viral genome integration into host DNA
GT391_RS15195	COG3228	Belongs to the MtfA family
GT391_RS15210	COG0401	homolog of Blt101
GT391_RS15215	COG3706	GGDEF domain
GT391_RS15215	COG0745	RESPONSE REGULATOR receiver
GT391_RS15230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GT391_RS15235	COG0303	'Molybdopterin
GT391_RS15240	COG4172	Belongs to the ABC transporter superfamily
GT391_RS15245	COG0747	negative chemotaxis
GT391_RS15250	COG0601	transmembrane transport
GT391_RS15255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT391_RS15260	COG0281	malic enzyme
GT391_RS15265	COG0295	cytidine deaminase activity
GT391_RS15270	COG1346	cytolysis
GT391_RS15275	COG1380	Effector of murein hydrolase LrgA
GT391_RS15280	COG5297	Belongs to the glycosyl hydrolase family 6
GT391_RS15285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GT391_RS15290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GT391_RS15295	COG0156	8-amino-7-oxononanoate synthase activity
GT391_RS15300	COG2226	methyltransferase
GT391_RS15305	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GT391_RS15310	COG0556	nucleotide-excision repair
GT391_RS15330	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GT391_RS15335	COG0521	Mo-molybdopterin cofactor biosynthetic process
GT391_RS15340	COG0315	cyclic pyranopterin monophosphate synthase activity
GT391_RS15345	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GT391_RS15350	COG0314	molybdopterin synthase activity
GT391_RS15355	COG0670	Belongs to the BI1 family
GT391_RS15360	COG0842	Transport permease protein
GT391_RS15365	COG0842	Transport permease protein
GT391_RS15370	COG1131	(ABC) transporter
GT391_RS15385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GT391_RS15390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT391_RS15395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT391_RS15400	COG1120	ATPase activity
GT391_RS15410	COG0513	Belongs to the DEAD box helicase family
GT391_RS15420	COG3708	Transcriptional regulator
GT391_RS15420	COG2207	Transcriptional regulator
GT391_RS15425	COG2195	Cleaves the N-terminal amino acid of tripeptides
GT391_RS15430	COG0747	negative chemotaxis
GT391_RS15435	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GT391_RS15440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GT391_RS15445	COG0833	amino acid
GT391_RS15450	COG2040	homocysteine
GT391_RS15475	COG1686	Belongs to the peptidase S11 family
GT391_RS15485	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GT391_RS15575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GT391_RS15655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GT391_RS15665	COG1126	abc transporter atp-binding protein
GT391_RS15670	COG0765	amino acid transport
GT391_RS15675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT391_RS15680	COG0783	Belongs to the Dps family
GT391_RS15685	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GT391_RS15685	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GT391_RS15695	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GT391_RS15700	COG2807	transmembrane transport
GT391_RS15705	COG0534	Mate efflux family protein
GT391_RS15710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GT391_RS15790	COG0582	viral genome integration into host DNA
GT391_RS15800	COG3083	sulfuric ester hydrolase activity
GT391_RS15805	COG3082	Protein of unknown function (DUF1414)
GT391_RS15810	COG3081	Nucleoid-associated protein
GT391_RS15820	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GT391_RS15825	COG1061	Type III restriction enzyme res subunit
GT391_RS15835	COG1187	pseudouridine synthase activity
GT391_RS15840	COG2814	Major facilitator Superfamily
GT391_RS15850	COG4172	Belongs to the ABC transporter superfamily
GT391_RS15855	COG4239	(ABC) transporter, permease
GT391_RS15860	COG4174	ABC transporter (Permease)
GT391_RS15865	COG4166	transmembrane transport
GT391_RS15870	COG0791	NLP P60 protein
GT391_RS15875	COG0671	phosphoesterase, PA-phosphatase related
GT391_RS15880	COG0523	cobalamin synthesis protein
GT391_RS15885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GT391_RS15900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT391_RS15900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT391_RS15905	COG1105	Belongs to the carbohydrate kinase PfkB family
GT391_RS15910	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GT391_RS15910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GT391_RS15910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GT391_RS15915	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GT391_RS15925	COG0583	DNA-binding transcription factor activity
GT391_RS15930	COG0833	amino acid
GT391_RS15935	COG4771	TonB-dependent receptor
GT391_RS15940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT391_RS15945	COG1172	Belongs to the binding-protein-dependent transport system permease family
GT391_RS15950	COG1129	ABC transporter
GT391_RS15955	COG0371	Dehydrogenase
GT391_RS15980	COG0583	DNA-binding transcription factor activity
GT391_RS15985	COG0840	transmembrane signaling receptor activity
GT391_RS15990	COG0302	gtp cyclohydrolase
GT391_RS15995	COG2311	Membrane
GT391_RS16000	COG2949	membrane
GT391_RS16005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GT391_RS16010	COG2133	pyrroloquinoline quinone binding
GT391_RS16015	COG0625	glutathione transferase activity
GT391_RS16025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GT391_RS16030	COG2011	ABC-type metal ion transport system permease component
GT391_RS16035	COG1686	Belongs to the peptidase S11 family
GT391_RS16040	COG1349	DNA-binding transcription factor activity
GT391_RS16045	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GT391_RS16050	COG2985	domain, Protein
GT391_RS16050	COG0569	domain protein
GT391_RS16060	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GT391_RS16065	COG0778	Nitroreductase
GT391_RS16070	COG0189	ligase activity
GT391_RS16080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GT391_RS16085	COG3842	ATPase activity
GT391_RS16090	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT391_RS16095	COG1177	transmembrane transport
GT391_RS16105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GT391_RS16110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT391_RS16115	COG4160	amino acid transport
GT391_RS16120	COG4215	(ABC) transporter
GT391_RS16125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT391_RS16130	COG1126	abc transporter atp-binding protein
GT391_RS16135	COG0393	Putative heavy-metal-binding
GT391_RS16140	COG3023	N-Acetylmuramoyl-L-alanine amidase
GT391_RS16145	COG0702	epimerase
GT391_RS16150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GT391_RS16155	COG1151	hydroxylamine reductase activity
GT391_RS16160	COG2431	L-lysine efflux transmembrane transporter activity
GT391_RS16165	COG3593	DNA synthesis involved in DNA repair
GT391_RS16170	COG1278	Cold shock
GT391_RS16175	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GT391_RS16180	COG0542	response to heat
GT391_RS16185	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GT391_RS16195	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GT391_RS16200	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GT391_RS16205	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GT391_RS16210	COG4988	ABC transporter
GT391_RS16215	COG0492	ferredoxin-NADP+ reductase activity
GT391_RS16225	COG3107	peptidoglycan biosynthetic process
GT391_RS16225	COG1674	ftsk spoiiie
GT391_RS16230	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GT391_RS16235	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GT391_RS16240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GT391_RS16245	COG2814	Major facilitator Superfamily
GT391_RS16270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GT391_RS16275	COG1882	Formate acetyltransferase
GT391_RS16280	COG2116	formate transmembrane transporter activity
GT391_RS16285	COG1944	ATP diphosphatase activity
GT391_RS16290	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GT391_RS16295	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GT391_RS16300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GT391_RS16305	COG0539	negative regulation of cytoplasmic translation
GT391_RS16310	COG0776	regulation of translation
GT391_RS16315	COG0140	phosphoribosyl-ATP diphosphatase activity
GT391_RS16315	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GT391_RS16320	COG0107	imidazoleglycerol-phosphate synthase activity
GT391_RS16325	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GT391_RS16330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GT391_RS16335	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GT391_RS16335	COG0131	Imidazoleglycerol-phosphate dehydratase
GT391_RS16340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GT391_RS16345	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GT391_RS16350	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GT391_RS16360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT391_RS16365	COG0840	transmembrane signaling receptor activity
GT391_RS16370	COG0840	transmembrane signaling receptor activity
GT391_RS16375	COG4565	transcriptional regulatory protein
GT391_RS16385	COG3493	citrate carrier protein
GT391_RS16390	COG0179	Fumarylacetoacetate (FAA) hydrolase
GT391_RS16395	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GT391_RS16400	COG3052	prosthetic group binding
GT391_RS16420	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GT391_RS16425	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GT391_RS16430	COG0531	amino acid
GT391_RS16435	COG2925	Exonuclease
GT391_RS16440	COG4607	ABC-type enterochelin transport system periplasmic component
GT391_RS16450	COG4605	iron ion homeostasis
GT391_RS16455	COG4604	ABC transporter, ATP-binding protein
GT391_RS16460	COG2926	Belongs to the UPF0265 family
GT391_RS16465	COG0658	competence protein
GT391_RS16465	COG2333	competence protein COMEC
GT391_RS16470	COG1132	(ABC) transporter
GT391_RS16475	COG1663	tetraacyldisaccharide 4'-kinase activity
GT391_RS16480	COG2835	tetraacyldisaccharide 4'-kinase activity
GT391_RS16485	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GT391_RS16495	COG3173	Aminoglycoside phosphotransferase
GT391_RS16500	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GT391_RS16505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GT391_RS16510	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GT391_RS16515	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GT391_RS16520	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GT391_RS16525	COG2989	Protein conserved in bacteria
GT391_RS16530	COG3108	Peptidase M15
GT391_RS16535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GT391_RS16540	COG1448	Aminotransferase
GT391_RS16550	COG0017	Asparaginyl-tRNA synthetase
GT391_RS16555	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GT391_RS16560	COG0308	aminopeptidase N
GT391_RS16565	COG0167	dihydroorotate dehydrogenase activity
GT391_RS16575	COG3217	Mosc domain protein beta barrel domain protein
GT391_RS16575	COG0633	Ferredoxin
GT391_RS16580	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GT391_RS16580	COG0116	Belongs to the methyltransferase superfamily
GT391_RS16585	COG0488	(ABC) transporter
GT391_RS16590	COG2995	paraquat-inducible protein a
GT391_RS16595	COG3008	intermembrane lipid transfer
GT391_RS16595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GT391_RS16600	COG3009	Protein conserved in bacteria
GT391_RS16605	COG3130	regulation of translation
GT391_RS16610	COG0840	transmembrane signaling receptor activity
GT391_RS16620	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GT391_RS16625	COG3381	protein complex oligomerization
GT391_RS16635	COG2999	glutathione oxidoreductase activity
GT391_RS16640	COG0477	Major facilitator Superfamily
GT391_RS16645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GT391_RS16650	COG3132	Protein of unknown function, DUF480
GT391_RS16660	COG0728	peptidoglycan biosynthetic process
GT391_RS16665	COG0018	arginyl-trna synthetase
GT391_RS16670	COG3102	Protein conserved in bacteria
GT391_RS16675	COG3142	Participates in the control of copper homeostasis
GT391_RS16680	COG0500	methyltransferase
GT391_RS16685	COG2226	methyltransferase
GT391_RS16690	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GT391_RS16695	COG1801	Protein of unknown function DUF72
GT391_RS16700	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GT391_RS16705	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GT391_RS16710	COG0494	nUDIX hydrolase
GT391_RS16715	COG0217	transcriptional regulatory protein
GT391_RS16720	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GT391_RS16725	COG0632	four-way junction helicase activity
GT391_RS16730	COG2255	four-way junction helicase activity
GT391_RS16735	COG4580	involved in the transport of maltose and maltodextrins
GT391_RS16740	COG1447	Phosphotransferase system cellobiose-specific component IIA
GT391_RS16745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GT391_RS16750	COG1609	Transcriptional regulator
GT391_RS16755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GT391_RS16760	COG1121	(ABC) transporter
GT391_RS16765	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GT391_RS16770	COG0739	heme binding
GT391_RS16775	COG1560	Kdo2-lipid A biosynthetic process
GT391_RS16780	COG0469	pyruvate kinase activity
GT391_RS16785	COG1737	Transcriptional regulator
GT391_RS16790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GT391_RS16795	COG0800	Aldolase
GT391_RS16800	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GT391_RS16805	COG1770	oligopeptidase
GT391_RS16815	COG1528	Iron-storage protein
GT391_RS16825	COG1278	Cold shock
GT391_RS16835	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GT391_RS16850	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GT391_RS16850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GT391_RS16855	COG3008	intermembrane lipid transfer
GT391_RS16860	COG2995	paraquat-inducible protein a
GT391_RS16865	COG1956	GAF domain-containing protein
GT391_RS16870	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GT391_RS16880	COG2207	Transcriptional regulator
GT391_RS16890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GT391_RS16895	COG1177	transmembrane transport
GT391_RS16900	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT391_RS16905	COG3842	ATPase activity
GT391_RS16910	COG2195	Cleaves the N-terminal amino acid of tripeptides
GT391_RS16915	COG2850	peptidyl-arginine hydroxylation
GT391_RS16930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GT391_RS16935	COG2915	High frequency lysogenization protein hflD homolog
GT391_RS16940	COG0482	sulfurtransferase activity
GT391_RS16950	COG1187	pseudouridine synthase activity
GT391_RS16955	COG0538	isocitrate dehydrogenase activity
GT391_RS16960	COG0348	domain, Protein
GT391_RS16980	COG5001	Diguanylate cyclase
GT391_RS16980	COG3300	MHYT domain
GT391_RS16985	COG3275	phosphorelay sensor kinase activity
GT391_RS16990	COG3279	Response regulator of the LytR AlgR family
GT391_RS16995	COG2223	nitrite transmembrane transporter activity
GT391_RS17000	COG1653	transport
GT391_RS17010	COG0501	Belongs to the peptidase M48B family
GT391_RS17015	COG0823	Involved in the tonB-independent uptake of proteins
GT391_RS17030	COG1113	amino acid transport
GT391_RS17035	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GT391_RS17040	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GT391_RS17045	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GT391_RS17050	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GT391_RS17060	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GT391_RS17065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GT391_RS17065	COG0072	phenylalanine-tRNA ligase activity
GT391_RS17070	COG0776	regulation of translation
GT391_RS17080	COG1132	(ABC) transporter
GT391_RS17090	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GT391_RS17095	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT391_RS17105	COG1988	membrane-bound metal-dependent
GT391_RS17110	COG0657	acetylesterase activity
GT391_RS17110	COG2755	lipolytic protein G-D-S-L family
GT391_RS17115	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GT391_RS17125	COG3842	ATPase activity
GT391_RS17130	COG0395	ABC-type sugar transport system, permease component
GT391_RS17135	COG1175	transmembrane transport
GT391_RS17145	COG1028	Short-chain dehydrogenase reductase Sdr
GT391_RS17155	COG1917	Cupin 2, conserved barrel domain protein
GT391_RS17160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT391_RS17175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GT391_RS17180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GT391_RS17185	COG1121	(ABC) transporter
GT391_RS17190	COG0803	Belongs to the bacterial solute-binding protein 9 family
GT391_RS17200	COG1278	Cold shock
GT391_RS17205	COG2226	methyltransferase
GT391_RS17210	COG1971	Probably functions as a manganese efflux pump
GT391_RS17215	COG4811	Protein of unknown function (DUF986)
GT391_RS17220	COG3716	PTS system mannose fructose sorbose family IID component
GT391_RS17225	COG3715	PTS system
GT391_RS17230	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT391_RS17230	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT391_RS17235	COG1253	flavin adenine dinucleotide binding
GT391_RS17240	COG1760	l-serine dehydratase
GT391_RS17245	COG0494	nUDIX hydrolase
GT391_RS17255	COG3140	Belongs to the UPF0181 family
GT391_RS17260	COG0251	oxidation-reduction process
GT391_RS17265	COG1199	ATP-dependent helicase activity
GT391_RS17275	COG3065	identical protein binding
GT391_RS17280	COG0318	PFAM AMP-dependent synthetase and ligase
GT391_RS17285	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GT391_RS17290	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GT391_RS17295	COG2894	cell division
GT391_RS17300	COG0850	regulation of cytokinetic process
GT391_RS17305	COG3100	YcgL domain-containing protein
GT391_RS17310	COG0179	Fumarylacetoacetate (FAA) hydrolase
GT391_RS17315	COG2983	Belongs to the UPF0260 family
GT391_RS17330	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GT391_RS17335	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GT391_RS17340	COG2186	Transcriptional regulator
GT391_RS17345	COG2719	SpoVR family
GT391_RS17350	COG3684	Belongs to the aldolase LacD family
GT391_RS17360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT391_RS17380	COG0205	6-phosphofructokinase activity
GT391_RS17385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT391_RS17400	COG2718	Belongs to the UPF0229 family
GT391_RS17405	COG2766	serine protein kinase
GT391_RS17410	COG3713	MltA-interacting MipA family protein
GT391_RS17415	COG0656	L-ascorbic acid biosynthetic process
GT391_RS17430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT391_RS17435	COG3139	Protein of unknown function (DUF1315)
GT391_RS17440	COG1335	isochorismatase
GT391_RS17445	COG0252	asparaginase activity
GT391_RS17450	COG0616	signal peptide processing
GT391_RS17455	COG0778	Nitroreductase
GT391_RS17460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GT391_RS17470	COG0708	Exodeoxyribonuclease III
GT391_RS17475	COG2860	membrane
GT391_RS17490	COG0788	formyltetrahydrofolate deformylase activity
GT391_RS17495	COG3012	SEC-C Motif Domain Protein
GT391_RS17500	COG1752	Esterase of the alpha-beta hydrolase superfamily
GT391_RS17505	COG0745	RESPONSE REGULATOR receiver
GT391_RS17510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GT391_RS17520	COG1435	thymidine kinase activity
GT391_RS17525	COG1454	alcohol dehydrogenase
GT391_RS17525	COG1012	belongs to the aldehyde dehydrogenase family
GT391_RS17540	COG0601	transmembrane transport
GT391_RS17545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT391_RS17550	COG0444	Belongs to the ABC transporter superfamily
GT391_RS17560	COG3099	Belongs to the UPF0263 family
GT391_RS17565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT391_RS17580	COG2350	Protein conserved in bacteria
GT391_RS17590	COG1607	acyl-coa hydrolase
GT391_RS17595	COG2917	probably involved in intracellular septation
GT391_RS17605	COG3047	cAMP biosynthetic process
GT391_RS17610	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GT391_RS17615	COG0159	tryptophan synthase activity
GT391_RS17620	COG0133	tryptophan synthase activity
GT391_RS17625	COG0135	phosphoribosylanthranilate isomerase activity
GT391_RS17625	COG0134	indole-3-glycerol-phosphate synthase activity
GT391_RS17630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GT391_RS17635	COG0512	Glutamine amidotransferase of anthranilate synthase
GT391_RS17645	COG0613	PHP domain protein
GT391_RS17650	COG0009	L-threonylcarbamoyladenylate synthase
GT391_RS17655	COG1187	pseudouridine synthase activity
GT391_RS17660	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GT391_RS17665	COG1028	Short-chain dehydrogenase reductase Sdr
GT391_RS17670	COG0616	signal peptide processing
GT391_RS17680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GT391_RS17690	COG3104	oligopeptide transport
GT391_RS17695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GT391_RS17705	COG4659	FMN binding
GT391_RS17710	COG4658	electron transport chain
GT391_RS17715	COG4656	Part of a membrane complex involved in electron transport
GT391_RS17720	COG2878	Part of a membrane complex involved in electron transport
GT391_RS17725	COG4657	Part of a membrane complex involved in electron transport
GT391_RS17735	COG2160	L-arabinose isomerase activity
GT391_RS17740	COG1069	ribulokinase activity
GT391_RS17745	COG1879	ABC-type sugar transport system periplasmic component
GT391_RS17750	COG1129	ABC transporter
GT391_RS17755	COG1172	Belongs to the binding-protein-dependent transport system permease family
GT391_RS17765	COG0673	inositol 2-dehydrogenase activity
GT391_RS17770	COG0385	Bile acid
GT391_RS17780	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GT391_RS17790	COG5339	Protein conserved in bacteria
GT391_RS17795	COG1482	cell wall glycoprotein biosynthetic process
GT391_RS17800	COG0114	fumarate hydratase activity
GT391_RS17810	COG2814	Major facilitator Superfamily
GT391_RS17815	COG0583	DNA-binding transcription factor activity
GT391_RS17820	COG1940	carbohydrate kinase activity
GT391_RS17825	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GT391_RS17830	COG2814	Major facilitator Superfamily
GT391_RS17850	COG4221	oxidoreductase activity
GT391_RS17855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GT391_RS17860	COG1215	transferase activity, transferring glycosyl groups
GT391_RS17885	COG1942	4-Oxalocrotonate Tautomerase
GT391_RS17890	COG0697	spore germination
GT391_RS17895	COG0076	glutamate decarboxylase activity
GT391_RS17900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GT391_RS17920	COG4628	conserved protein (DUF2132)
GT391_RS17930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GT391_RS18000	COG0456	acetyltransferase
GT391_RS18005	COG0738	Major facilitator superfamily
GT391_RS18015	COG3783	Cytochrome b(562)
GT391_RS18020	COG1764	response to oxidative stress
GT391_RS18025	COG4305	rare lipoprotein A
GT391_RS18060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GT391_RS18075	COG0673	inositol 2-dehydrogenase activity
GT391_RS18080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GT391_RS18085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT391_RS18095	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GT391_RS18100	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GT391_RS18120	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GT391_RS18125	COG2912	Transglutaminase-like superfamily
GT391_RS18130	COG3094	Invasion gene expression up-regulator, SirB
GT391_RS18135	COG2890	protein-(glutamine-N5) methyltransferase activity
GT391_RS18140	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GT391_RS18145	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GT391_RS18150	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GT391_RS18155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GT391_RS18160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GT391_RS18170	COG0193	aminoacyl-tRNA hydrolase activity
GT391_RS18175	COG0012	GTP binding
GT391_RS18195	COG2200	EAL domain
GT391_RS18200	COG0789	Transcriptional regulator
GT391_RS18210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GT391_RS18245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GT391_RS18260	COG0523	cobalamin synthesis protein
GT391_RS18265	COG3443	Belongs to the bacterial solute-binding protein 9 family
GT391_RS18270	COG0346	lactoylglutathione lyase activity
GT391_RS18275	COG0483	inositol monophosphate 1-phosphatase activity
GT391_RS18280	COG2723	6-phospho-beta-galactosidase activity
GT391_RS18285	COG1263	PTS System
GT391_RS18285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT391_RS18290	COG1609	Transcriptional regulator
GT391_RS18315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT391_RS18330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT391_RS18340	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GT391_RS18350	COG0765	amino acid transport
GT391_RS18355	COG1126	abc transporter atp-binding protein
GT391_RS18370	COG1129	ABC transporter
GT391_RS18380	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT391_RS18390	COG1802	Transcriptional regulator
GT391_RS18490	COG2831	hemolysin activation secretion protein
GT391_RS18495	COG1802	Transcriptional regulator
GT391_RS18580	COG2200	EAL domain
GT391_RS18590	COG2197	response regulator
GT391_RS18595	COG3850	Histidine kinase
GT391_RS18620	COG1157	protein secretion by the type III secretion system
GT391_RS18645	COG4794	Type iii secretion
GT391_RS18655	COG4792	protein secretion
GT391_RS18660	COG0583	DNA-binding transcription factor activity
GT391_RS18675	COG1464	Belongs to the NlpA lipoprotein family
GT391_RS18680	COG4948	Mandelate Racemase Muconate Lactonizing
GT391_RS18685	COG2011	ABC-type metal ion transport system permease component
GT391_RS18690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GT391_RS18695	COG0671	phosphoesterase, PA-phosphatase related
GT391_RS18715	COG1028	Short-chain dehydrogenase reductase Sdr
GT391_RS18725	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT391_RS18735	COG1012	belongs to the aldehyde dehydrogenase family
GT391_RS18740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GT391_RS18750	COG3842	ATPase activity
GT391_RS18755	COG2261	transglycosylase associated protein
GT391_RS18760	COG0322	excinuclease ABC activity
GT391_RS18765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GT391_RS18770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GT391_RS18785	COG2423	ornithine cyclodeaminase activity
GT391_RS18795	COG1846	Transcriptional regulator
GT391_RS18800	COG0697	spore germination
GT391_RS18805	COG2181	nitrate reductase activity
GT391_RS18810	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GT391_RS18815	COG1140	nitrate reductase beta subunit
GT391_RS18820	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GT391_RS18825	COG2223	nitrite transmembrane transporter activity
GT391_RS18830	COG3850	Histidine kinase
GT391_RS18835	COG2197	response regulator
GT391_RS18850	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GT391_RS18860	COG0387	Pfam Sodium calcium exchanger
GT391_RS18865	COG0659	secondary active sulfate transmembrane transporter activity
GT391_RS18875	COG1028	Short-chain dehydrogenase reductase Sdr
GT391_RS18895	COG0745	RESPONSE REGULATOR receiver
GT391_RS18900	COG2205	protein histidine kinase activity
GT391_RS18915	COG3591	Belongs to the peptidase S1B family
GT391_RS18920	COG3300	MHYT domain
GT391_RS18920	COG5001	Diguanylate cyclase
GT391_RS18930	COG1643	Atp-dependent helicase
GT391_RS18935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GT391_RS18945	COG2911	Protein conserved in bacteria
GT391_RS18950	COG0840	transmembrane signaling receptor activity
GT391_RS18955	COG0840	transmembrane signaling receptor activity
GT391_RS18960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT391_RS18985	COG0037	tRNA processing
GT391_RS18990	COG0598	Magnesium transport protein CorA
GT391_RS18995	COG4166	transmembrane transport
GT391_RS19000	COG2866	Carboxypeptidase
GT391_RS19005	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GT391_RS19020	COG3768	UPF0283 membrane protein
GT391_RS19025	COG3106	COG3106 Predicted ATPase
GT391_RS19030	COG2831	hemolysin activation secretion protein
GT391_RS19040	COG3210	domain, Protein
GT391_RS19055	COG1983	PspC domain protein
GT391_RS19065	COG1842	Phage shock protein A
GT391_RS19070	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GT391_RS19090	COG4166	transmembrane transport
GT391_RS19095	COG4168	peptide transport system, permease
GT391_RS19100	COG4171	peptide transport system, permease
GT391_RS19125	COG1053	succinate dehydrogenase
GT391_RS19135	COG2271	Major facilitator Superfamily
GT391_RS19140	COG1609	Transcriptional regulator
GT391_RS19145	COG0583	DNA-binding transcription factor activity
GT391_RS19150	COG0243	molybdopterin cofactor binding
GT391_RS19155	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GT391_RS19160	COG4989	oxidoreductase activity
GT391_RS19170	COG2814	Major facilitator Superfamily
GT391_RS19175	COG1966	Carbon starvation protein
GT391_RS19180	COG0235	Class ii aldolase
GT391_RS19190	COG0023	Translation Initiation Factor
GT391_RS19195	COG0284	orotidine-5'-phosphate decarboxylase activity
GT391_RS19200	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GT391_RS19205	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GT391_RS19215	COG1082	Xylose isomerase domain protein TIM barrel
GT391_RS19220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GT391_RS19225	COG3958	Transketolase
GT391_RS19230	COG3959	Transketolase, thiamine diphosphate binding domain
GT391_RS19235	COG1172	Belongs to the binding-protein-dependent transport system permease family
GT391_RS19240	COG1129	ABC transporter
GT391_RS19255	COG0671	phosphoesterase, PA-phosphatase related
GT391_RS19260	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GT391_RS19280	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GT391_RS19285	COG1301	dicarboxylic acid transport
GT391_RS19290	COG0625	glutathione transferase activity
GT391_RS19295	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GT391_RS19300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GT391_RS19305	COG0259	pyridoxamine-phosphate oxidase activity
GT391_RS19310	COG3895	Periplasmic Protein
GT391_RS19315	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GT391_RS19320	COG3133	Outer membrane lipoprotein
GT391_RS19330	COG3313	Fe-S protein
GT391_RS19335	COG0346	lactoylglutathione lyase activity
GT391_RS19340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GT391_RS19345	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GT391_RS19350	COG0791	NLP P60 protein
GT391_RS19360	COG1609	Transcriptional regulator
GT391_RS19365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GT391_RS19370	COG0307	riboflavin synthase, alpha
GT391_RS19375	COG0534	Mate efflux family protein
GT391_RS19385	COG1620	l-lactate permease
GT391_RS19390	COG0247	lactate metabolic process
GT391_RS19395	COG1139	Iron-sulfur cluster binding protein
GT391_RS19400	COG1556	Lactate utilization protein
GT391_RS19405	COG1794	racemase activity, acting on amino acids and derivatives
GT391_RS19410	COG1942	4-Oxalocrotonate Tautomerase
GT391_RS19430	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GT391_RS19435	COG1408	metallophosphoesterase
GT391_RS19445	COG0561	phosphatase activity
GT391_RS19450	COG2076	Multidrug Resistance protein
GT391_RS19475	COG2197	response regulator
GT391_RS19480	COG3850	Histidine kinase
GT391_RS19485	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GT391_RS19485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GT391_RS19490	COG3062	negative regulation of establishment of protein localization
GT391_RS19495	COG0243	molybdopterin cofactor binding
GT391_RS19500	COG0437	4 iron, 4 sulfur cluster binding
GT391_RS19505	COG0348	domain, Protein
GT391_RS19510	COG3043	anaerobic respiration
GT391_RS19515	COG3005	denitrification pathway
GT391_RS19520	COG3088	subunit of a heme lyase
GT391_RS19520	COG4235	cytochrome complex assembly
GT391_RS19525	COG4235	cytochrome complex assembly
GT391_RS19525	COG3088	subunit of a heme lyase
GT391_RS19530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GT391_RS19535	COG1138	Cytochrome C-type biogenesis protein
GT391_RS19540	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GT391_RS19545	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GT391_RS19550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GT391_RS19555	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GT391_RS19560	COG4133	protoheme IX ABC transporter activity
GT391_RS19565	COG4235	cytochrome complex assembly
GT391_RS19570	COG3088	subunit of a heme lyase
GT391_RS19575	COG1138	Cytochrome C-type biogenesis protein
GT391_RS19580	COG3301	Polysulphide reductase, NrfD
GT391_RS19585	COG0437	4 iron, 4 sulfur cluster binding
GT391_RS19590	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GT391_RS19595	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GT391_RS19605	COG2382	esterase
GT391_RS19640	COG4238	major outer membrane lipoprotein
GT391_RS19645	COG1388	LysM domain
GT391_RS19645	COG1376	ErfK ybiS ycfS ynhG family protein
GT391_RS19650	COG2166	iron-sulfur cluster assembly
GT391_RS19655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GT391_RS19660	COG0719	Fe-S assembly protein
GT391_RS19665	COG0396	ATPase activity
GT391_RS19670	COG0719	Fe-S assembly protein
GT391_RS19675	COG0316	Belongs to the HesB IscA family
GT391_RS19685	COG2050	protein possibly involved in aromatic compounds catabolism
GT391_RS19690	COG0277	FAD linked oxidase domain protein
GT391_RS19690	COG0247	lactate metabolic process
GT391_RS19695	COG0628	permease
GT391_RS19705	COG1477	protein flavinylation
GT391_RS19710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GT391_RS19710	COG0574	Belongs to the PEP-utilizing enzyme family
GT391_RS19715	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GT391_RS19720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GT391_RS19730	COG2188	Transcriptional regulator
GT391_RS19745	COG3720	iron ion transport
GT391_RS19750	COG4558	Periplasmic binding protein
GT391_RS19755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT391_RS19760	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GT391_RS19765	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GT391_RS19770	COG0095	Lipoate-protein ligase
GT391_RS19775	COG0791	NLP P60 protein
GT391_RS19780	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GT391_RS19785	COG0386	Belongs to the glutathione peroxidase family
GT391_RS19790	COG4139	cobalamin transport
GT391_RS19795	COG2226	methyltransferase
GT391_RS19810	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GT391_RS19815	COG1940	carbohydrate kinase activity
GT391_RS19820	COG4591	ABC-type transport system involved in lipoprotein release permease component
GT391_RS19825	COG1136	(ABC) transporter
GT391_RS19830	COG4591	ABC-type transport system involved in lipoprotein release permease component
GT391_RS19835	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GT391_RS19840	COG0443	Heat shock 70 kDa protein
GT391_RS19845	COG1309	transcriptional regulator
GT391_RS19855	COG2814	Major facilitator Superfamily
GT391_RS19860	COG3134	Outer membrane lipoprotein
GT391_RS19865	COG1252	NADH dehydrogenase
GT391_RS19870	COG3150	esterase
GT391_RS19875	COG1472	Belongs to the glycosyl hydrolase 3 family
GT391_RS19885	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
GT391_RS19895	COG0537	adenosine 5'-monophosphoramidase activity
GT391_RS19900	COG0477	Major facilitator Superfamily
GT391_RS19910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT391_RS19910	COG1263	PTS System
GT391_RS19915	COG0084	hydrolase, TatD family'
GT391_RS19920	COG0470	DNA polymerase III
GT391_RS19925	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GT391_RS19930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GT391_RS19935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GT391_RS19940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GT391_RS19945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GT391_RS19950	COG1028	Short-chain dehydrogenase reductase Sdr
GT391_RS19955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GT391_RS19960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GT391_RS19965	COG0416	fatty acid biosynthetic process
GT391_RS19970	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GT391_RS19975	COG1399	metal-binding, possibly nucleic acid-binding protein
GT391_RS19980	COG0424	maF-like protein
GT391_RS19985	COG0564	pseudouridine synthase activity
GT391_RS19990	COG1530	ribonuclease E activity
GT391_RS19990	COG1530	ribonuclease E activity
GT391_RS20000	COG0418	dihydroorotase activity
GT391_RS20020	COG3038	cytochrome b561
GT391_RS20025	COG2353	YceI-like domain
GT391_RS20035	COG1902	pentaerythritol trinitrate reductase activity
GT391_RS20040	COG1560	Kdo2-lipid A biosynthetic process
GT391_RS20045	COG2943	transferase activity, transferring hexosyl groups
GT391_RS20050	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GT391_RS20065	COG0840	transmembrane signaling receptor activity
GT391_RS20085	COG0589	response to stress
GT391_RS20115	COG0670	Belongs to the BI1 family
GT391_RS20120	COG2920	part of a sulfur-relay system
GT391_RS20125	COG1254	Belongs to the acylphosphatase family
GT391_RS20130	COG3785	DNA binding
GT391_RS20135	COG1832	CoA-binding protein
GT391_RS20145	COG1803	Methylglyoxal synthase
GT391_RS20150	COG0210	DNA helicase
GT391_RS20155	COG3304	Inner membrane component domain
GT391_RS20160	COG1289	transmembrane transporter activity
GT391_RS20165	COG3070	regulator of competence-specific genes
GT391_RS20170	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
GT391_RS20185	COG1067	ATP-dependent peptidase activity
GT391_RS20190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GT391_RS20195	COG2979	Protein of unknown function (DUF533)
GT391_RS20200	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GT391_RS20205	COG1012	belongs to the aldehyde dehydrogenase family
GT391_RS20210	COG1309	transcriptional regulator
GT391_RS20215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GT391_RS20230	COG1702	phosphate starvation-inducible protein PhoH
GT391_RS20240	COG1191	sigma factor activity
GT391_RS20275	COG0500	methyltransferase
GT391_RS20300	COG1677	Flagellar hook-basal body complex protein FliE
GT391_RS20310	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GT391_RS20315	COG1317	bacterial-type flagellum organization
GT391_RS20325	COG2882	bacterial-type flagellum organization
GT391_RS20335	COG1580	Controls the rotational direction of flagella during chemotaxis
GT391_RS20375	COG1256	bacterial-type flagellum assembly
GT391_RS20385	COG1706	bacterial-type flagellum-dependent cell motility
GT391_RS20390	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GT391_RS20395	COG4786	Flagellar basal body rod
GT391_RS20405	COG1749	Flagellar hook protein flgE
GT391_RS20410	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GT391_RS20415	COG1558	bacterial-type flagellum-dependent cell motility
GT391_RS20420	COG1815	bacterial-type flagellum-dependent cell motility
GT391_RS20430	COG2747	anti-sigma28 factor FlgM
GT391_RS20435	COG3418	PFAM FlgN family protein
GT391_RS20445	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT391_RS20450	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT391_RS20460	COG0745	RESPONSE REGULATOR receiver
GT391_RS20465	COG2201	protein-glutamate methylesterase activity
GT391_RS20470	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GT391_RS20475	COG0840	transmembrane signaling receptor activity
GT391_RS20480	COG0835	chemotaxis
GT391_RS20485	COG0643	Histidine kinase
GT391_RS20485	COG2198	Histidine kinase
GT391_RS20510	COG0697	spore germination
GT391_RS20515	COG0840	transmembrane signaling receptor activity
GT391_RS20570	COG2003	Belongs to the UPF0758 family
GT391_RS20585	COG3596	GTP binding
GT391_RS20610	COG3501	Rhs element vgr protein
GT391_RS20665	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GT391_RS20665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT391_RS20680	COG0326	Molecular chaperone. Has ATPase activity
GT391_RS20690	COG0582	viral genome integration into host DNA
GT391_RS20710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GT391_RS20715	COG0322	excinuclease ABC activity
GT391_RS20720	COG2197	response regulator
GT391_RS20740	COG1113	amino acid transport
GT391_RS20760	COG0582	viral genome integration into host DNA
GT391_RS20775	COG3423	Transcriptional regulator
GT391_RS20845	COG3736	Type IV secretory pathway, component VirB8
GT391_RS20850	COG3504	Conjugal transfer protein
GT391_RS20855	COG2948	multi-organism process
GT391_RS20860	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
GT391_RS20880	COG1522	sequence-specific DNA binding
GT391_RS20890	COG0582	viral genome integration into host DNA
GT391_RS20905	COG4227	nucleotidyltransferase activity
GT391_RS20910	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GT391_RS20910	COG0517	IMP dehydrogenase activity
GT391_RS20915	COG2723	6-phospho-beta-galactosidase activity
GT391_RS20925	COG3226	Transcriptional regulator
GT391_RS20930	COG0738	Major facilitator superfamily
GT391_RS20950	COG1376	ErfK ybiS ycfS ynhG family protein
GT391_RS20970	COG3272	Protein of unknown function (DUF1722)
GT391_RS20990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GT391_RS21005	COG0300	oxidoreductase activity
GT391_RS21015	COG0789	Transcriptional regulator
GT391_RS21040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GT391_RS21045	COG3122	Protein conserved in bacteria
GT391_RS21060	COG2723	6-phospho-beta-galactosidase activity
GT391_RS21065	COG0789	Transcriptional regulator
GT391_RS21065	COG4978	Transcriptional regulator
GT391_RS21070	COG2814	Major facilitator Superfamily
GT391_RS21085	COG1733	regulation of RNA biosynthetic process
GT391_RS21090	COG0640	Transcriptional regulator
GT391_RS21095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GT391_RS21110	COG0625	glutathione transferase activity
GT391_RS21115	COG2814	Major facilitator Superfamily
GT391_RS21120	COG3226	Transcriptional regulator
GT391_RS21130	COG0784	Response regulator, receiver
GT391_RS21130	COG0835	chemotaxis
GT391_RS21145	COG2995	paraquat-inducible protein a
GT391_RS21150	COG3008	intermembrane lipid transfer
GT391_RS21150	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GT391_RS21155	COG3009	Protein conserved in bacteria
GT391_RS21170	COG1132	(ABC) transporter
GT391_RS21195	COG4771	TonB-dependent receptor
GT391_RS21215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT391_RS21230	COG5464	transposase or invertase
GT391_RS21235	COG0444	Belongs to the ABC transporter superfamily
GT391_RS21250	COG0747	negative chemotaxis
GT391_RS21255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT391_RS21260	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GT391_RS21270	COG0477	Major facilitator Superfamily
GT391_RS21280	COG2226	methyltransferase
GT391_RS21290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GT391_RS21295	COG1012	belongs to the aldehyde dehydrogenase family
GT391_RS21310	COG1629	transport
GT391_RS21310	COG4206	TonB-dependent receptor
GT391_RS21335	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GT391_RS21345	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GT391_RS21350	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GT391_RS21355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT391_RS21375	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GT391_RS21380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT391_RS21385	COG0371	Dehydrogenase
GT391_RS21390	COG1301	dicarboxylic acid transport
GT391_RS21410	COG0697	spore germination
GT391_RS21415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GT391_RS21420	COG1136	(ABC) transporter
GT391_RS21420	COG0577	efflux transmembrane transporter activity
GT391_RS21430	COG0577	efflux transmembrane transporter activity
GT391_RS21430	COG1136	(ABC) transporter
GT391_RS21445	COG0672	)-iron permease
GT391_RS21460	COG3383	formate dehydrogenase (NAD+) activity
GT391_RS21465	COG2851	Citrate transporter
GT391_RS21475	COG1301	dicarboxylic acid transport
GT391_RS21480	COG0583	DNA-binding transcription factor activity
GT391_RS21495	COG1464	Belongs to the NlpA lipoprotein family
GT391_RS21510	COG2271	Major facilitator Superfamily
GT391_RS21515	COG1840	ABC-type Fe3 transport system, periplasmic component
GT391_RS21525	COG3842	ATPase activity
GT391_RS21530	COG1609	Transcriptional regulator
GT391_RS21535	COG3250	beta-galactosidase activity
GT391_RS21540	COG2223	nitrite transmembrane transporter activity