locus-tag	class	description
F126LOC_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F126LOC_RS00010	COG0592	DNA-directed DNA polymerase activity
F126LOC_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F126LOC_RS00035	COG0840	transmembrane signaling receptor activity
F126LOC_RS00040	COG1609	Transcriptional regulator
F126LOC_RS00045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F126LOC_RS00050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F126LOC_RS00055	COG1447	Phosphotransferase system cellobiose-specific component IIA
F126LOC_RS00060	COG2723	6-phospho-beta-galactosidase activity
F126LOC_RS00065	COG0561	phosphatase activity
F126LOC_RS00075	COG0747	negative chemotaxis
F126LOC_RS00080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F126LOC_RS00095	COG0601	transmembrane transport
F126LOC_RS00100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F126LOC_RS00115	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
F126LOC_RS00120	COG2186	Transcriptional regulator
F126LOC_RS00125	COG3734	2-keto-3-deoxy-galactonokinase
F126LOC_RS00130	COG0800	Aldolase
F126LOC_RS00135	COG4948	Mandelate Racemase Muconate Lactonizing
F126LOC_RS00140	COG2271	Major facilitator Superfamily
F126LOC_RS00150	COG1116	anion transmembrane transporter activity
F126LOC_RS00155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F126LOC_RS00160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F126LOC_RS00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F126LOC_RS00180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F126LOC_RS00180	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F126LOC_RS00185	COG2723	6-phospho-beta-galactosidase activity
F126LOC_RS00195	COG0823	Involved in the tonB-independent uptake of proteins
F126LOC_RS00200	COG5645	(Lipo)protein
F126LOC_RS00205	COG0071	Belongs to the small heat shock protein (HSP20) family
F126LOC_RS00210	COG0071	Belongs to the small heat shock protein (HSP20) family
F126LOC_RS00215	COG0569	domain protein
F126LOC_RS00215	COG2985	domain, Protein
F126LOC_RS00220	COG0471	metal ion transport
F126LOC_RS00225	COG3290	protein histidine kinase activity
F126LOC_RS00230	COG4565	transcriptional regulatory protein
F126LOC_RS00265	COG3493	citrate carrier protein
F126LOC_RS00275	COG0747	negative chemotaxis
F126LOC_RS00280	COG0601	transmembrane transport
F126LOC_RS00285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F126LOC_RS00290	COG0444	Belongs to the ABC transporter superfamily
F126LOC_RS00295	COG4608	Belongs to the ABC transporter superfamily
F126LOC_RS00320	COG3501	Rhs element vgr protein
F126LOC_RS00330	COG3977	Valine--pyruvate aminotransferase
F126LOC_RS00355	COG3210	domain, Protein
F126LOC_RS00360	COG2831	hemolysin activation secretion protein
F126LOC_RS00365	COG3118	belongs to the thioredoxin family
F126LOC_RS00365	COG0457	Tetratricopeptide repeat
F126LOC_RS00370	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
F126LOC_RS00380	COG1215	transferase activity, transferring glycosyl groups
F126LOC_RS00385	COG1192	Involved in chromosome partitioning
F126LOC_RS00405	COG2194	sulfuric ester hydrolase activity
F126LOC_RS00410	COG2199	diguanylate cyclase activity
F126LOC_RS00410	COG2200	EAL domain
F126LOC_RS00415	COG1301	dicarboxylic acid transport
F126LOC_RS00420	COG0612	Peptidase, M16
F126LOC_RS00425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F126LOC_RS00430	COG1295	ribonuclease BN
F126LOC_RS00435	COG0477	Major facilitator Superfamily
F126LOC_RS00445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F126LOC_RS00450	COG0425	Belongs to the sulfur carrier protein TusA family
F126LOC_RS00460	COG3714	YhhN family
F126LOC_RS00470	COG3776	membrane
F126LOC_RS00475	COG0742	ribosomal rna small subunit methyltransferase
F126LOC_RS00480	COG0552	protein localization to endoplasmic reticulum
F126LOC_RS00485	COG2884	Cell division ATP-binding protein ftsE
F126LOC_RS00490	COG2177	Part of the ABC transporter FtsEX involved in
F126LOC_RS00505	COG0683	leucine binding
F126LOC_RS00510	COG0559	Belongs to the binding-protein-dependent transport system permease family
F126LOC_RS00515	COG4177	L-phenylalanine transmembrane transporter activity
F126LOC_RS00520	COG0411	ABC transporter
F126LOC_RS00525	COG0410	ABC transporter
F126LOC_RS00530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F126LOC_RS00540	COG0840	transmembrane signaling receptor activity
F126LOC_RS00545	COG0840	transmembrane signaling receptor activity
F126LOC_RS00550	COG0840	transmembrane signaling receptor activity
F126LOC_RS00555	COG2610	gluconate transmembrane transporter activity
F126LOC_RS00560	COG3622	Belongs to the hyi family
F126LOC_RS00565	COG0235	Class ii aldolase
F126LOC_RS00570	COG3395	kinase activity
F126LOC_RS00575	COG2084	Dehydrogenase
F126LOC_RS00580	COG1349	DNA-binding transcription factor activity
F126LOC_RS00615	COG1653	transport
F126LOC_RS00620	COG1175	transmembrane transport
F126LOC_RS00625	COG0395	ABC-type sugar transport system, permease component
F126LOC_RS00630	COG3842	ATPase activity
F126LOC_RS00635	COG0584	glycerophosphoryl diester phosphodiesterase
F126LOC_RS00650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F126LOC_RS00665	COG2205	protein histidine kinase activity
F126LOC_RS00670	COG0745	RESPONSE REGULATOR receiver
F126LOC_RS00675	COG3678	ATP-independent chaperone mediated protein folding
F126LOC_RS00690	COG2814	Major facilitator Superfamily
F126LOC_RS00695	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F126LOC_RS00700	COG0205	6-phosphofructokinase activity
F126LOC_RS00705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F126LOC_RS00710	COG2957	Belongs to the agmatine deiminase family
F126LOC_RS00725	COG0149	triose-phosphate isomerase activity
F126LOC_RS00735	COG3152	Membrane
F126LOC_RS00745	COG1494	fructose-1,6-bisphosphatase
F126LOC_RS00755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F126LOC_RS00760	COG3074	FtsZ-dependent cytokinesis
F126LOC_RS00765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F126LOC_RS00770	COG1575	Belongs to the MenA family. Type 1 subfamily
F126LOC_RS00775	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
F126LOC_RS00780	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
F126LOC_RS00785	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F126LOC_RS00790	COG1609	Transcriptional regulator
F126LOC_RS00795	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F126LOC_RS00800	COG0254	rRNA binding
F126LOC_RS00805	COG1598	PFAM Uncharacterised protein family UPF0150
F126LOC_RS00815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F126LOC_RS00825	COG1120	ATPase activity
F126LOC_RS00830	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
F126LOC_RS00835	COG0626	cystathionine gamma-synthase activity
F126LOC_RS00840	COG0527	aspartate kinase activity
F126LOC_RS00840	COG0460	homoserine dehydrogenase
F126LOC_RS00845	COG3842	ATPase activity
F126LOC_RS00860	COG0395	ABC-type sugar transport system, permease component
F126LOC_RS00865	COG1609	Transcriptional regulator
F126LOC_RS00870	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F126LOC_RS00885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F126LOC_RS00900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F126LOC_RS00905	COG4206	TonB-dependent receptor
F126LOC_RS00910	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F126LOC_RS00950	COG1879	ABC-type sugar transport system periplasmic component
F126LOC_RS00955	COG1129	ABC transporter
F126LOC_RS00960	COG1172	Belongs to the binding-protein-dependent transport system permease family
F126LOC_RS00965	COG1172	Belongs to the binding-protein-dependent transport system permease family
F126LOC_RS00970	COG0583	DNA-binding transcription factor activity
F126LOC_RS00975	COG3085	chromosome segregation
F126LOC_RS00995	COG3978	acetolactate synthase activity
F126LOC_RS01005	COG0129	dihydroxy-acid dehydratase activity
F126LOC_RS01025	COG0583	DNA-binding transcription factor activity
F126LOC_RS01030	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F126LOC_RS01040	COG0506	proline dehydrogenase activity
F126LOC_RS01040	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F126LOC_RS01040	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F126LOC_RS01045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F126LOC_RS01050	COG0210	DNA helicase
F126LOC_RS01055	COG0248	Ppx GppA phosphatase
F126LOC_RS01060	COG0513	Belongs to the DEAD box helicase family
F126LOC_RS01065	COG3118	belongs to the thioredoxin family
F126LOC_RS01070	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F126LOC_RS01075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F126LOC_RS01080	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
F126LOC_RS01085	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F126LOC_RS01090	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F126LOC_RS01095	COG1088	dTDP-glucose 4,6-dehydratase activity
F126LOC_RS01100	COG0456	acetyltransferase
F126LOC_RS01105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F126LOC_RS01110	COG2244	polysaccharide biosynthetic process
F126LOC_RS01115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F126LOC_RS01125	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
F126LOC_RS01160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F126LOC_RS01165	COG0456	acetyltransferase
F126LOC_RS01170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F126LOC_RS01175	COG0765	amino acid transport
F126LOC_RS01180	COG1126	abc transporter atp-binding protein
F126LOC_RS01185	COG1473	amidohydrolase
F126LOC_RS01190	COG3071	HemY protein
F126LOC_RS01195	COG2959	enzyme of heme biosynthesis
F126LOC_RS01200	COG1587	Uroporphyrinogen-III synthase
F126LOC_RS01205	COG0181	hydroxymethylbilane synthase activity
F126LOC_RS01215	COG2814	Major facilitator Superfamily
F126LOC_RS01220	COG1965	Belongs to the frataxin family
F126LOC_RS01230	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F126LOC_RS01245	COG1011	Hydrolase
F126LOC_RS01250	COG0210	DNA helicase
F126LOC_RS01255	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
F126LOC_RS01260	COG0598	Magnesium transport protein CorA
F126LOC_RS01265	COG3180	Ammonia monooxygenase
F126LOC_RS01275	COG2050	protein possibly involved in aromatic compounds catabolism
F126LOC_RS01285	COG0514	ATP-dependent DNA helicase (RecQ)
F126LOC_RS01290	COG1280	lysine exporter protein (LysE YggA)
F126LOC_RS01295	COG1280	lysine exporter protein (LysE YggA)
F126LOC_RS01300	COG2267	carboxylic ester hydrolase activity
F126LOC_RS01305	COG0561	phosphatase activity
F126LOC_RS01310	COG0584	glycerophosphoryl diester phosphodiesterase
F126LOC_RS01315	COG2271	Major facilitator Superfamily
F126LOC_RS01320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F126LOC_RS01325	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
F126LOC_RS01330	COG0247	lactate metabolic process
F126LOC_RS01340	COG1741	Belongs to the pirin family
F126LOC_RS01345	COG1609	Transcriptional regulator
F126LOC_RS01350	COG3265	gluconokinase activity
F126LOC_RS01355	COG2610	gluconate transmembrane transporter activity
F126LOC_RS01360	COG2095	MarC family integral membrane protein
F126LOC_RS01365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F126LOC_RS01375	COG3275	phosphorelay sensor kinase activity
F126LOC_RS01380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F126LOC_RS01385	COG1523	belongs to the glycosyl hydrolase 13 family
F126LOC_RS01390	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
F126LOC_RS01395	COG0297	glycogen (starch) synthase activity
F126LOC_RS01400	COG0058	SHG alpha-glucan phosphorylase activity
F126LOC_RS01405	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F126LOC_RS01410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F126LOC_RS01415	COG0705	Rhomboid family
F126LOC_RS01420	COG1349	DNA-binding transcription factor activity
F126LOC_RS01425	COG0058	SHG alpha-glucan phosphorylase activity
F126LOC_RS01430	COG1640	4-alpha-glucanotransferase
F126LOC_RS01435	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
F126LOC_RS01435	COG0316	Belongs to the HesB IscA family
F126LOC_RS01440	COG1040	competence protein
F126LOC_RS01445	COG2267	carboxylic ester hydrolase activity
F126LOC_RS01450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F126LOC_RS01465	COG1785	Belongs to the alkaline phosphatase family
F126LOC_RS01495	COG1414	Transcriptional regulator
F126LOC_RS01500	COG2183	response to ionizing radiation
F126LOC_RS01510	COG0840	transmembrane signaling receptor activity
F126LOC_RS01520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F126LOC_RS01530	COG4264	IucA IucC family
F126LOC_RS01535	COG4774	siderophore transport
F126LOC_RS01540	COG0019	diaminopimelate decarboxylase activity
F126LOC_RS01545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F126LOC_RS01550	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F126LOC_RS01555	COG2814	Major facilitator Superfamily
F126LOC_RS01580	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
F126LOC_RS01585	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
F126LOC_RS01590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F126LOC_RS01595	COG1011	Hydrolase
F126LOC_RS01605	COG0494	nUDIX hydrolase
F126LOC_RS01615	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F126LOC_RS01640	COG4796	Type ii and iii secretion system protein
F126LOC_RS01645	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F126LOC_RS01650	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
F126LOC_RS01665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F126LOC_RS01670	COG0546	phosphoglycolate phosphatase activity
F126LOC_RS01680	COG1473	amidohydrolase
F126LOC_RS01705	COG1648	precorrin-2 dehydrogenase activity
F126LOC_RS01705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F126LOC_RS01715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F126LOC_RS01720	COG4948	Mandelate Racemase Muconate Lactonizing
F126LOC_RS01725	COG0747	negative chemotaxis
F126LOC_RS01730	COG0601	transmembrane transport
F126LOC_RS01735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F126LOC_RS01740	COG0444	Belongs to the ABC transporter superfamily
F126LOC_RS01745	COG4608	Belongs to the ABC transporter superfamily
F126LOC_RS01750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F126LOC_RS01770	COG3866	Pectate lyase
F126LOC_RS01810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F126LOC_RS01815	COG1765	OsmC-like protein
F126LOC_RS01820	COG3954	Phosphoribulokinase
F126LOC_RS01825	COG3089	Belongs to the UPF0270 family
F126LOC_RS01830	COG0429	hydrolase of the alpha beta-hydrolase fold
F126LOC_RS01845	COG3853	Toxic anion resistance protein (TelA)
F126LOC_RS01850	COG0488	(ABC) transporter
F126LOC_RS01855	COG2249	NAD(P)H dehydrogenase (quinone) activity
F126LOC_RS01860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F126LOC_RS01860	COG0475	glutathione-regulated potassium exporter activity
F126LOC_RS01865	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
F126LOC_RS01870	COG1047	Peptidyl-prolyl cis-trans
F126LOC_RS01875	COG2900	Belongs to the SlyX family
F126LOC_RS01880	COG0545	Peptidyl-prolyl cis-trans isomerase
F126LOC_RS01885	COG3385	transposase activity
F126LOC_RS01900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F126LOC_RS01905	COG0642	Histidine kinase
F126LOC_RS01910	COG0745	RESPONSE REGULATOR receiver
F126LOC_RS01920	COG2964	Protein conserved in bacteria
F126LOC_RS01925	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F126LOC_RS01930	COG2923	Belongs to the DsrF TusC family
F126LOC_RS01935	COG2168	tRNA wobble position uridine thiolation
F126LOC_RS01940	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F126LOC_RS01945	COG0049	tRNA binding
F126LOC_RS01950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F126LOC_RS01965	COG2193	ferroxidase activity
F126LOC_RS01970	COG0051	transcription antitermination factor activity, RNA binding
F126LOC_RS01975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F126LOC_RS01980	COG0088	Forms part of the polypeptide exit tunnel
F126LOC_RS01990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F126LOC_RS01995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F126LOC_RS02000	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
F126LOC_RS02005	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
F126LOC_RS02010	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F126LOC_RS02015	COG0255	Belongs to the universal ribosomal protein uL29 family
F126LOC_RS02020	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
F126LOC_RS02030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
F126LOC_RS02035	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F126LOC_RS02040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
F126LOC_RS02045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F126LOC_RS02050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F126LOC_RS02055	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
F126LOC_RS02060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F126LOC_RS02065	COG1841	ribosomal large subunit assembly
F126LOC_RS02070	COG0200	Binds to the 23S rRNA
F126LOC_RS02075	COG0201	protein transport
F126LOC_RS02080	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F126LOC_RS02085	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F126LOC_RS02095	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
F126LOC_RS02100	COG0202	RNA polymerase activity
F126LOC_RS02105	COG0203	ribosomal protein L17
F126LOC_RS02110	COG3036	rescue of stalled ribosome
F126LOC_RS02115	COG1970	mechanosensitive ion channel activity
F126LOC_RS02120	COG0569	domain protein
F126LOC_RS02125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F126LOC_RS02125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F126LOC_RS02130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F126LOC_RS02135	COG0242	peptide deformylase activity
F126LOC_RS02140	COG0758	DNA mediated transformation
F126LOC_RS02145	COG2922	Belongs to the Smg family
F126LOC_RS02150	COG0551	DNA topoisomerase type I activity
F126LOC_RS02155	COG0009	L-threonylcarbamoyladenylate synthase
F126LOC_RS02160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F126LOC_RS02170	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F126LOC_RS02195	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
F126LOC_RS02200	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F126LOC_RS02210	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
F126LOC_RS02225	COG0646	methionine synthase
F126LOC_RS02225	COG1410	methionine synthase
F126LOC_RS02230	COG2207	Transcriptional regulator
F126LOC_RS02245	COG0471	metal ion transport
F126LOC_RS02255	COG0527	aspartate kinase activity
F126LOC_RS02260	COG0166	Belongs to the GPI family
F126LOC_RS02270	COG1509	lysine 2,3-aminomutase activity
F126LOC_RS02275	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F126LOC_RS02290	COG3040	lipid binding
F126LOC_RS02295	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
F126LOC_RS02300	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
F126LOC_RS02305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F126LOC_RS02310	COG1053	succinate dehydrogenase
F126LOC_RS02315	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
F126LOC_RS02320	COG1511	domain protein
F126LOC_RS02320	COG3264	Mechanosensitive ion channel
F126LOC_RS02325	COG0688	phosphatidylethanolamine metabolic process
F126LOC_RS02330	COG1162	GTPase activity
F126LOC_RS02335	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F126LOC_RS02375	COG1011	Hydrolase
F126LOC_RS02395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F126LOC_RS02400	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F126LOC_RS02420	COG1064	alcohol dehydrogenase
F126LOC_RS02425	COG1704	LemA family
F126LOC_RS02440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F126LOC_RS02465	COG1136	(ABC) transporter
F126LOC_RS02470	COG1136	(ABC) transporter
F126LOC_RS02470	COG0577	efflux transmembrane transporter activity
F126LOC_RS02495	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F126LOC_RS02510	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F126LOC_RS02515	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F126LOC_RS02515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F126LOC_RS02520	COG0802	atpase or kinase
F126LOC_RS02530	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F126LOC_RS02535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F126LOC_RS02540	COG1923	regulation of RNA biosynthetic process
F126LOC_RS02545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F126LOC_RS02550	COG0330	HflC and HflK could
F126LOC_RS02555	COG0330	HflC and HflK could
F126LOC_RS02560	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
F126LOC_RS02565	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F126LOC_RS02570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F126LOC_RS02575	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F126LOC_RS02580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F126LOC_RS02585	COG1678	Uncharacterized ACR, COG1678
F126LOC_RS02590	COG0189	ligase activity
F126LOC_RS02595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F126LOC_RS02600	COG2356	endonuclease I
F126LOC_RS02605	COG3091	SprT-like family
F126LOC_RS02610	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F126LOC_RS02620	COG1166	arginine decarboxylase activity
F126LOC_RS02630	COG0501	Belongs to the peptidase M48B family
F126LOC_RS02635	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F126LOC_RS02640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F126LOC_RS02645	COG0126	phosphoglycerate kinase activity
F126LOC_RS02650	COG0191	fructose-bisphosphate aldolase activity
F126LOC_RS02655	COG0668	transmembrane transport
F126LOC_RS02660	COG1279	arginine transmembrane transporter activity
F126LOC_RS02670	COG0583	DNA-binding transcription factor activity
F126LOC_RS02675	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
F126LOC_RS02680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F126LOC_RS02685	COG0604	alcohol dehydrogenase
F126LOC_RS02690	COG0583	DNA-binding transcription factor activity
F126LOC_RS02695	COG0840	transmembrane signaling receptor activity
F126LOC_RS02700	COG0488	(ABC) transporter
F126LOC_RS02710	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
F126LOC_RS02715	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
F126LOC_RS02725	COG2207	Transcriptional regulator
F126LOC_RS02725	COG3708	Transcriptional regulator
F126LOC_RS02730	COG3045	CreA protein
F126LOC_RS02735	COG0745	RESPONSE REGULATOR receiver
F126LOC_RS02740	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
F126LOC_RS02755	COG0083	homoserine kinase activity
F126LOC_RS02765	COG3022	response to hydroperoxide
F126LOC_RS02770	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F126LOC_RS02780	COG0521	Mo-molybdopterin cofactor biosynthetic process
F126LOC_RS02790	COG1584	GPR1 FUN34 yaaH family protein
F126LOC_RS02795	COG0443	Heat shock 70 kDa protein
F126LOC_RS02800	COG0484	heat shock protein binding
F126LOC_RS02805	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F126LOC_RS02810	COG0583	DNA-binding transcription factor activity
F126LOC_RS02815	COG0268	Binds directly to 16S ribosomal RNA
F126LOC_RS02820	COG0196	riboflavin kinase activity
F126LOC_RS02825	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F126LOC_RS02835	COG1047	Peptidyl-prolyl cis-trans
F126LOC_RS02840	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
F126LOC_RS02845	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F126LOC_RS02850	COG0505	Belongs to the CarA family
F126LOC_RS02855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F126LOC_RS02865	COG2966	Psort location CytoplasmicMembrane, score
F126LOC_RS02870	COG3610	response to peptide
F126LOC_RS02875	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F126LOC_RS02895	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F126LOC_RS02900	COG2967	ApaG domain
F126LOC_RS02905	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F126LOC_RS02910	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F126LOC_RS02915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F126LOC_RS02920	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F126LOC_RS02925	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F126LOC_RS02930	COG0564	pseudouridine synthase activity
F126LOC_RS02935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F126LOC_RS02940	COG0417	DNA replication proofreading
F126LOC_RS02945	COG3706	GGDEF domain
F126LOC_RS02950	COG0586	Pfam SNARE associated Golgi protein
F126LOC_RS02955	COG0440	acetolactate synthase activity
F126LOC_RS02960	COG0028	Belongs to the TPP enzyme family
F126LOC_RS02965	COG3507	Belongs to the glycosyl hydrolase 43 family
F126LOC_RS02970	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
F126LOC_RS02975	COG1178	ABC-type Fe3 transport system permease component
F126LOC_RS02980	COG4143	(ABC) transporter
F126LOC_RS02985	COG4533	DNA binding
F126LOC_RS03000	COG3033	Beta-eliminating lyase
F126LOC_RS03010	COG0840	transmembrane signaling receptor activity
F126LOC_RS03030	COG0066	3-isopropylmalate dehydratase activity
F126LOC_RS03035	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
F126LOC_RS03040	COG0473	3-isopropylmalate dehydrogenase activity
F126LOC_RS03045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F126LOC_RS03050	COG1022	Amp-dependent synthetase and ligase
F126LOC_RS03055	COG0028	Belongs to the TPP enzyme family
F126LOC_RS03075	COG2001	Belongs to the MraZ family
F126LOC_RS03080	COG0275	rRNA processing
F126LOC_RS03085	COG3116	cell division
F126LOC_RS03090	COG0768	penicillin binding
F126LOC_RS03095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F126LOC_RS03100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F126LOC_RS03105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F126LOC_RS03110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F126LOC_RS03115	COG0772	Belongs to the SEDS family
F126LOC_RS03120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F126LOC_RS03125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F126LOC_RS03130	COG1181	Belongs to the D-alanine--D-alanine ligase family
F126LOC_RS03135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F126LOC_RS03140	COG0849	cell division
F126LOC_RS03145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F126LOC_RS03150	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
F126LOC_RS03165	COG0653	protein targeting
F126LOC_RS03170	COG0494	nUDIX hydrolase
F126LOC_RS03175	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F126LOC_RS03180	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
F126LOC_RS03185	COG0237	dephospho-CoA kinase activity
F126LOC_RS03190	COG0516	GMP reductase activity
F126LOC_RS03195	COG1459	type II secretion system
F126LOC_RS03200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F126LOC_RS03205	COG4969	Belongs to the N-Me-Phe pilin family
F126LOC_RS03210	COG0157	Belongs to the NadC ModD family
F126LOC_RS03215	COG3248	Nucleoside-binding outer membrane protein
F126LOC_RS03220	COG3023	N-Acetylmuramoyl-L-alanine amidase
F126LOC_RS03225	COG3725	Membrane protein required for beta-lactamase induction
F126LOC_RS03230	COG3940	Belongs to the glycosyl hydrolase 43 family
F126LOC_RS03235	COG2211	Major facilitator Superfamily
F126LOC_RS03240	COG1113	amino acid transport
F126LOC_RS03250	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F126LOC_RS03255	COG0508	dehydrogenase complex catalyzes the overall conversion of
F126LOC_RS03260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F126LOC_RS03265	COG0583	DNA-binding transcription factor activity
F126LOC_RS03285	COG1073	alpha beta
F126LOC_RS03295	COG2079	MmgE PrpD family protein
F126LOC_RS03300	COG2207	Transcriptional regulator
F126LOC_RS03310	COG0640	Transcriptional regulator
F126LOC_RS03330	COG3112	Uncharacterised protein family (UPF0231)
F126LOC_RS03335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F126LOC_RS03350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F126LOC_RS03355	COG1609	Transcriptional regulator
F126LOC_RS03380	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F126LOC_RS03385	COG1882	Formate acetyltransferase
F126LOC_RS03390	COG1028	Short-chain dehydrogenase reductase Sdr
F126LOC_RS03395	COG2731	YhcH YjgK YiaL family protein
F126LOC_RS03410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F126LOC_RS03415	COG1454	alcohol dehydrogenase
F126LOC_RS03420	COG3395	kinase activity
F126LOC_RS03425	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F126LOC_RS03430	COG1349	DNA-binding transcription factor activity
F126LOC_RS03440	COG0803	Belongs to the bacterial solute-binding protein 9 family
F126LOC_RS03445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F126LOC_RS03450	COG1121	(ABC) transporter
F126LOC_RS03460	COG2971	BadF BadG BcrA BcrD
F126LOC_RS03480	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F126LOC_RS03485	COG3842	ATPase activity
F126LOC_RS03490	COG1175	transmembrane transport
F126LOC_RS03495	COG0395	ABC-type sugar transport system, permease component
F126LOC_RS03515	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F126LOC_RS03560	COG3547	Transposase (IS116 IS110 IS902 family)
F126LOC_RS03570	COG0629	single-stranded DNA binding
F126LOC_RS03580	COG0432	Pfam Uncharacterised protein family UPF0047
F126LOC_RS03610	COG1203	CRISPR-associated helicase, Cas3
F126LOC_RS03615	COG1518	maintenance of DNA repeat elements
F126LOC_RS03645	COG1451	nucleotide metabolic process
F126LOC_RS03650	COG1448	Aminotransferase
F126LOC_RS03660	COG1522	sequence-specific DNA binding
F126LOC_RS03680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F126LOC_RS03695	COG2124	cytochrome p450
F126LOC_RS03710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F126LOC_RS03730	COG0583	DNA-binding transcription factor activity
F126LOC_RS03735	COG0583	DNA-binding transcription factor activity
F126LOC_RS03750	COG1396	sequence-specific DNA binding
F126LOC_RS03755	COG1609	Transcriptional regulator
F126LOC_RS03760	COG1447	Phosphotransferase system cellobiose-specific component IIA
F126LOC_RS03765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F126LOC_RS03770	COG2723	6-phospho-beta-galactosidase activity
F126LOC_RS03775	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F126LOC_RS03780	COG2186	Transcriptional regulator
F126LOC_RS03790	COG0318	PFAM AMP-dependent synthetase and ligase
F126LOC_RS03790	COG0204	Acyl-transferase
F126LOC_RS03795	COG0477	Major facilitator Superfamily
F126LOC_RS03800	COG2153	protein acetylation
F126LOC_RS03825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F126LOC_RS03830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F126LOC_RS03835	COG1872	DUF167
F126LOC_RS03840	COG0762	integral membrane protein
F126LOC_RS03845	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F126LOC_RS03850	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F126LOC_RS03855	COG2805	Type II/IV secretion system protein
F126LOC_RS03865	COG0840	transmembrane signaling receptor activity
F126LOC_RS03870	COG1959	2 iron, 2 sulfur cluster binding
F126LOC_RS03875	COG0557	exoribonuclease II activity
F126LOC_RS03880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F126LOC_RS03885	COG0840	transmembrane signaling receptor activity
F126LOC_RS03890	COG3766	membrane
F126LOC_RS03910	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
F126LOC_RS03915	COG1690	Belongs to the RtcB family
F126LOC_RS03920	COG0840	transmembrane signaling receptor activity
F126LOC_RS03925	COG1073	alpha beta
F126LOC_RS03930	COG0360	Binds together with S18 to 16S ribosomal RNA
F126LOC_RS03935	COG2965	DNA replication, synthesis of RNA primer
F126LOC_RS03940	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F126LOC_RS03945	COG0359	binds to the 23S rRNA
F126LOC_RS03955	COG3061	Opacity-associated protein A
F126LOC_RS03960	COG0545	Peptidyl-prolyl cis-trans isomerase
F126LOC_RS03965	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
F126LOC_RS03970	COG3961	Belongs to the TPP enzyme family
F126LOC_RS03985	COG1733	regulation of RNA biosynthetic process
F126LOC_RS03990	COG0737	Belongs to the 5'-nucleotidase family
F126LOC_RS03995	COG1218	3'(2'),5'-bisphosphate nucleotidase
F126LOC_RS04000	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
F126LOC_RS04010	COG3547	Transposase (IS116 IS110 IS902 family)
F126LOC_RS04015	COG1253	flavin adenine dinucleotide binding
F126LOC_RS04020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F126LOC_RS04025	COG0729	surface antigen
F126LOC_RS04030	COG2911	Protein conserved in bacteria
F126LOC_RS04035	COG2105	PFAM AIG2 family protein
F126LOC_RS04040	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F126LOC_RS04045	COG0840	transmembrane signaling receptor activity
F126LOC_RS04050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
F126LOC_RS04055	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F126LOC_RS04060	COG1968	undecaprenyl-diphosphatase activity
F126LOC_RS04065	COG0617	tRNA 3'-terminal CCA addition
F126LOC_RS04070	COG4991	sh3 domain protein
F126LOC_RS04075	COG3025	triphosphatase activity
F126LOC_RS04080	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F126LOC_RS04085	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
F126LOC_RS04085	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
F126LOC_RS04090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F126LOC_RS04095	COG3530	Putative quorum-sensing-regulated virulence factor
F126LOC_RS04110	COG0840	transmembrane signaling receptor activity
F126LOC_RS04115	COG2721	sulfolactate sulfo-lyase activity
F126LOC_RS04120	COG2271	Major facilitator Superfamily
F126LOC_RS04125	COG4948	Mandelate Racemase Muconate Lactonizing
F126LOC_RS04130	COG4948	Mandelate Racemase Muconate Lactonizing
F126LOC_RS04140	COG2084	Dehydrogenase
F126LOC_RS04145	COG1929	Belongs to the glycerate kinase type-1 family
F126LOC_RS04155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F126LOC_RS04160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F126LOC_RS04170	COG3956	TIGRFAM MazG family protein
F126LOC_RS04175	COG0504	CTP synthase activity
F126LOC_RS04180	COG0148	phosphopyruvate hydratase activity
F126LOC_RS04190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F126LOC_RS04205	COG0583	DNA-binding transcription factor activity
F126LOC_RS04215	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F126LOC_RS04225	COG1028	Short-chain dehydrogenase reductase Sdr
F126LOC_RS04230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F126LOC_RS04235	COG0602	queuosine metabolic process
F126LOC_RS04240	COG0720	synthase
F126LOC_RS04260	COG2200	EAL domain
F126LOC_RS04270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F126LOC_RS04275	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F126LOC_RS04280	COG0175	sulfate reduction
F126LOC_RS04290	COG0444	Belongs to the ABC transporter superfamily
F126LOC_RS04305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F126LOC_RS04310	COG0584	glycerophosphoryl diester phosphodiesterase
F126LOC_RS04315	COG1648	precorrin-2 dehydrogenase activity
F126LOC_RS04315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F126LOC_RS04320	COG0175	sulfate reduction
F126LOC_RS04325	COG2895	sulfate adenylyltransferase (ATP) activity
F126LOC_RS04330	COG0529	Catalyzes the synthesis of activated sulfate
F126LOC_RS04340	COG1126	abc transporter atp-binding protein
F126LOC_RS04345	COG0765	amino acid transport
F126LOC_RS04355	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F126LOC_RS04360	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
F126LOC_RS04365	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
F126LOC_RS04370	COG0585	pseudouridine synthase activity
F126LOC_RS04375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F126LOC_RS04380	COG4942	peptidase
F126LOC_RS04380	COG1388	LysM domain
F126LOC_RS04390	COG0442	prolyl-tRNA aminoacylation
F126LOC_RS04395	COG1720	tRNA m6t6A37 methyltransferase activity
F126LOC_RS04405	COG1464	Belongs to the NlpA lipoprotein family
F126LOC_RS04410	COG2011	ABC-type metal ion transport system permease component
F126LOC_RS04415	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F126LOC_RS04420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F126LOC_RS04455	COG0477	Major facilitator Superfamily
F126LOC_RS04460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F126LOC_RS04465	COG1042	CoA-binding domain protein
F126LOC_RS04465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F126LOC_RS04465	COG0045	succinate-CoA ligase (ADP-forming) activity
F126LOC_RS04470	COG3148	PFAM DTW domain containing protein
F126LOC_RS04475	COG3118	belongs to the thioredoxin family
F126LOC_RS04480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F126LOC_RS04490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F126LOC_RS04495	COG2814	Major facilitator Superfamily
F126LOC_RS04500	COG1566	PFAM secretion protein HlyD family protein
F126LOC_RS04505	COG1846	Transcriptional regulator
F126LOC_RS04515	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F126LOC_RS04520	COG2814	Major facilitator Superfamily
F126LOC_RS04525	COG2706	6-phosphogluconolactonase activity
F126LOC_RS04535	COG0596	Alpha beta hydrolase
F126LOC_RS04540	COG2113	Glycine betaine
F126LOC_RS04545	COG4176	ABC-type proline glycine betaine transport system permease component
F126LOC_RS04550	COG4175	Glycine betaine
F126LOC_RS04595	COG0765	amino acid transport
F126LOC_RS04605	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F126LOC_RS04620	COG0436	Aminotransferase
F126LOC_RS04625	COG0235	Class ii aldolase
F126LOC_RS04630	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
F126LOC_RS04635	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
F126LOC_RS04640	COG3501	Rhs element vgr protein
F126LOC_RS04670	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
F126LOC_RS04675	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
F126LOC_RS04685	COG1960	acyl-CoA dehydrogenase activity
F126LOC_RS04690	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
F126LOC_RS04695	COG0121	glutamine amidotransferase
F126LOC_RS04700	COG3034	peptidoglycan biosynthetic process
F126LOC_RS04705	COG2226	methyltransferase
F126LOC_RS04715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F126LOC_RS04720	COG2195	Cleaves the N-terminal amino acid of tripeptides
F126LOC_RS04725	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
F126LOC_RS04730	COG1073	alpha beta
F126LOC_RS04755	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F126LOC_RS04760	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
F126LOC_RS04850	COG3829	transcription factor binding
F126LOC_RS04885	COG3501	Rhs element vgr protein
F126LOC_RS04980	COG2999	glutathione oxidoreductase activity
F126LOC_RS04990	COG2814	Major facilitator Superfamily
F126LOC_RS05015	COG1546	Belongs to the CinA family
F126LOC_RS05020	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F126LOC_RS05025	COG2137	regulation of response to DNA damage stimulus
F126LOC_RS05030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F126LOC_RS05035	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
F126LOC_RS05060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F126LOC_RS05065	COG1238	metal cluster binding
F126LOC_RS05070	COG2918	glutathione biosynthetic process
F126LOC_RS05075	COG1854	S-ribosylhomocysteine lyase activity
F126LOC_RS05080	COG4137	Cytochrome C assembly protein
F126LOC_RS05085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F126LOC_RS05090	COG0228	four-way junction DNA binding
F126LOC_RS05095	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F126LOC_RS05100	COG0336	Belongs to the RNA methyltransferase TrmD family
F126LOC_RS05105	COG0335	large ribosomal subunit rRNA binding
F126LOC_RS05120	COG2264	protein methyltransferase activity
F126LOC_RS05130	COG3279	Response regulator of the LytR AlgR family
F126LOC_RS05135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F126LOC_RS05140	COG1605	Chorismate mutase
F126LOC_RS05140	COG0287	Prephenate dehydrogenase
F126LOC_RS05145	COG1605	Chorismate mutase
F126LOC_RS05145	COG0077	Prephenate dehydratase
F126LOC_RS05150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F126LOC_RS05155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F126LOC_RS05160	COG0564	pseudouridine synthase activity
F126LOC_RS05170	COG0542	response to heat
F126LOC_RS05205	COG3021	interspecies interaction between organisms
F126LOC_RS05210	COG1388	LysM domain
F126LOC_RS05210	COG0741	lytic transglycosylase activity
F126LOC_RS05215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F126LOC_RS05220	COG2226	methyltransferase
F126LOC_RS05225	COG0328	RNA-DNA hybrid ribonuclease activity
F126LOC_RS05240	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F126LOC_RS05250	COG1780	Probably involved in ribonucleotide reductase function
F126LOC_RS05255	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F126LOC_RS05260	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
F126LOC_RS05265	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
F126LOC_RS05280	COG3842	ATPase activity
F126LOC_RS05295	COG0288	reversible hydration of carbon dioxide
F126LOC_RS05300	COG1131	(ABC) transporter
F126LOC_RS05305	COG0842	Transport permease protein
F126LOC_RS05310	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
F126LOC_RS05315	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F126LOC_RS05320	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F126LOC_RS05325	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F126LOC_RS05335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F126LOC_RS05345	COG1489	DNA binding
F126LOC_RS05350	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F126LOC_RS05355	COG1643	Atp-dependent helicase
F126LOC_RS05360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F126LOC_RS05365	COG1120	ATPase activity
F126LOC_RS05370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F126LOC_RS05375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F126LOC_RS05385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F126LOC_RS05390	COG0625	glutathione transferase activity
F126LOC_RS05395	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
F126LOC_RS05400	COG0316	Belongs to the HesB IscA family
F126LOC_RS05410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F126LOC_RS05415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F126LOC_RS05420	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F126LOC_RS05425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F126LOC_RS05430	COG3835	regulator
F126LOC_RS05435	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F126LOC_RS05445	COG4208	sulfate ABC transporter
F126LOC_RS05450	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F126LOC_RS05460	COG1309	transcriptional regulator
F126LOC_RS05465	COG0667	Aldo Keto reductase
F126LOC_RS05470	COG1902	pentaerythritol trinitrate reductase activity
F126LOC_RS05495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F126LOC_RS05500	COG2819	hydrolase of the alpha beta superfamily
F126LOC_RS05515	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F126LOC_RS05520	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
F126LOC_RS05525	COG0513	Belongs to the DEAD box helicase family
F126LOC_RS05530	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
F126LOC_RS05535	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F126LOC_RS05550	COG3026	antisigma factor binding
F126LOC_RS05555	COG3086	response to oxidative stress
F126LOC_RS05560	COG0481	GTPase activity
F126LOC_RS05570	COG0571	ribonuclease III activity
F126LOC_RS05575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F126LOC_RS05580	COG1381	Involved in DNA repair and RecF pathway recombination
F126LOC_RS05585	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F126LOC_RS05590	COG0736	holo-[acyl-carrier-protein] synthase activity
F126LOC_RS05595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F126LOC_RS05600	COG2200	EAL domain
F126LOC_RS05610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F126LOC_RS05615	COG2274	protein secretion by the type I secretion system
F126LOC_RS05635	COG2199	diguanylate cyclase activity
F126LOC_RS05635	COG2200	EAL domain
F126LOC_RS05635	COG3287	FIST C domain
F126LOC_RS05645	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F126LOC_RS05650	COG0560	Phosphoserine phosphatase
F126LOC_RS05660	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
F126LOC_RS05665	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F126LOC_RS05665	COG0047	phosphoribosylformylglycinamidine synthase activity
F126LOC_RS05670	COG2205	protein histidine kinase activity
F126LOC_RS05675	COG3170	Tfp pilus assembly protein FimV
F126LOC_RS05680	COG2204	response regulator
F126LOC_RS05685	COG0347	Belongs to the P(II) protein family
F126LOC_RS05690	COG4677	pectinesterase activity
F126LOC_RS05700	COG1017	nitric oxide dioxygenase activity
F126LOC_RS05700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F126LOC_RS05705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F126LOC_RS05710	COG2814	Major facilitator Superfamily
F126LOC_RS05715	COG3683	transport system, periplasmic component
F126LOC_RS05720	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F126LOC_RS05730	COG0840	transmembrane signaling receptor activity
F126LOC_RS05740	COG1120	ATPase activity
F126LOC_RS05745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F126LOC_RS05755	COG0483	inositol monophosphate 1-phosphatase activity
F126LOC_RS05760	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
F126LOC_RS05765	COG1959	2 iron, 2 sulfur cluster binding
F126LOC_RS05770	COG1104	cysteine desulfurase activity
F126LOC_RS05775	COG0822	iron-sulfur transferase activity
F126LOC_RS05780	COG0316	Belongs to the HesB IscA family
F126LOC_RS05785	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F126LOC_RS05790	COG0443	Heat shock 70 kDa protein
F126LOC_RS05795	COG0633	Ferredoxin
F126LOC_RS05800	COG2975	iron-sulfur cluster assembly
F126LOC_RS05805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F126LOC_RS05815	COG1737	Transcriptional regulator
F126LOC_RS05820	COG2897	thiosulfate sulfurtransferase activity
F126LOC_RS05825	COG1486	melibiose metabolic process
F126LOC_RS05830	COG2190	(PTS) system
F126LOC_RS05830	COG1263	PTS System
F126LOC_RS05830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F126LOC_RS05835	COG0105	UTP biosynthetic process
F126LOC_RS05840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F126LOC_RS05850	COG1426	Protein conserved in bacteria
F126LOC_RS05855	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
F126LOC_RS05860	COG0124	histidyl-tRNA synthetase
F126LOC_RS05865	COG2976	Protein conserved in bacteria
F126LOC_RS05870	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F126LOC_RS05875	COG1160	GTP binding
F126LOC_RS05890	COG1645	bacterial-type flagellum-dependent swarming motility
F126LOC_RS05905	COG1570	exodeoxyribonuclease VII activity
F126LOC_RS05910	COG0517	IMP dehydrogenase activity
F126LOC_RS05910	COG0516	GMP reductase activity
F126LOC_RS05915	COG0519	Catalyzes the synthesis of GMP from XMP
F126LOC_RS05915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F126LOC_RS05930	COG3423	Transcriptional regulator
F126LOC_RS05955	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F126LOC_RS05995	COG3706	GGDEF domain
F126LOC_RS06000	COG1064	alcohol dehydrogenase
F126LOC_RS06005	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
F126LOC_RS06010	COG0351	phosphomethylpyrimidine kinase
F126LOC_RS06015	COG3223	Belongs to the PsiE family
F126LOC_RS06020	COG1597	lipid kinase activity
F126LOC_RS06025	COG0826	peptidase U32
F126LOC_RS06030	COG0435	Glutathione S-transferase
F126LOC_RS06045	COG0745	RESPONSE REGULATOR receiver
F126LOC_RS06050	COG2205	protein histidine kinase activity
F126LOC_RS06055	COG0477	Major facilitator Superfamily
F126LOC_RS06060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F126LOC_RS06065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F126LOC_RS06070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F126LOC_RS06075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F126LOC_RS06090	COG1874	Beta-galactosidase
F126LOC_RS06095	COG3867	Arabinogalactan endo-beta-1,4-galactanase
F126LOC_RS06100	COG3833	ABC-type maltose transport systems, permease component
F126LOC_RS06105	COG1175	transmembrane transport
F126LOC_RS06110	COG2182	Extracellular solute-binding protein
F126LOC_RS06115	COG3842	ATPase activity
F126LOC_RS06120	COG4580	involved in the transport of maltose and maltodextrins
F126LOC_RS06125	COG1609	Transcriptional regulator
F126LOC_RS06140	COG2239	Acts as a magnesium transporter
F126LOC_RS06145	COG1846	Transcriptional regulator
F126LOC_RS06150	COG1764	response to oxidative stress
F126LOC_RS06170	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
F126LOC_RS06175	COG0573	inorganic phosphate transmembrane transporter activity
F126LOC_RS06180	COG0581	inorganic phosphate transmembrane transporter activity
F126LOC_RS06185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F126LOC_RS06195	COG1760	l-serine dehydratase
F126LOC_RS06200	COG0814	amino acid
F126LOC_RS06205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F126LOC_RS06210	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F126LOC_RS06215	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F126LOC_RS06220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F126LOC_RS06230	COG0215	cysteine-tRNA ligase activity
F126LOC_RS06235	COG2501	S4 domain
F126LOC_RS06240	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
F126LOC_RS06245	COG5001	Diguanylate cyclase
F126LOC_RS06245	COG4251	negative regulation of phosphorylation
F126LOC_RS06245	COG3706	GGDEF domain
F126LOC_RS06245	COG2203	Gaf domain
F126LOC_RS06250	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F126LOC_RS06255	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F126LOC_RS06260	COG0463	Glycosyl transferase, family 2
F126LOC_RS06265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F126LOC_RS06265	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F126LOC_RS06270	COG0726	polysaccharide deacetylase
F126LOC_RS06275	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F126LOC_RS06280	COG2076	Multidrug Resistance protein
F126LOC_RS06285	COG2076	Multidrug Resistance protein
F126LOC_RS06290	COG3842	ATPase activity
F126LOC_RS06305	COG1447	Phosphotransferase system cellobiose-specific component IIA
F126LOC_RS06335	COG1696	Membrane protein involved in D-alanine export
F126LOC_RS06340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F126LOC_RS06355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F126LOC_RS06385	COG1511	domain protein
F126LOC_RS06385	COG3264	Mechanosensitive ion channel
F126LOC_RS06395	COG4948	Mandelate Racemase Muconate Lactonizing
F126LOC_RS06400	COG0436	Aminotransferase
F126LOC_RS06410	COG3266	domain, Protein
F126LOC_RS06415	COG3866	Pectate lyase
F126LOC_RS06495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F126LOC_RS06500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F126LOC_RS06505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F126LOC_RS06510	COG1120	ATPase activity
F126LOC_RS06520	COG0513	Belongs to the DEAD box helicase family
F126LOC_RS06560	COG2814	Major facilitator Superfamily
F126LOC_RS06565	COG1522	sequence-specific DNA binding
F126LOC_RS06600	COG2116	formate transmembrane transporter activity
F126LOC_RS06610	COG0579	oxidoreductase
F126LOC_RS06615	COG0583	DNA-binding transcription factor activity
F126LOC_RS06620	COG1028	Short-chain dehydrogenase reductase Sdr
F126LOC_RS06625	COG2067	long-chain fatty acid transport protein
F126LOC_RS06630	COG3691	Protein conserved in bacteria
F126LOC_RS06635	COG4106	trans-aconitate 2-methyltransferase activity
F126LOC_RS06645	COG0183	Belongs to the thiolase family
F126LOC_RS06650	COG1024	Enoyl-CoA hydratase
F126LOC_RS06650	COG1250	3-hydroxyacyl-CoA dehydrogenase
F126LOC_RS06660	COG3188	usher protein
F126LOC_RS06680	COG2062	phosphohistidine phosphatase, SixA
F126LOC_RS06685	COG2840	Smr protein MutS2
F126LOC_RS06690	COG2890	protein-(glutamine-N5) methyltransferase activity
F126LOC_RS06695	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
F126LOC_RS06700	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
F126LOC_RS06705	COG0730	response to heat
F126LOC_RS06710	COG3101	peptidyl-lysine hydroxylation
F126LOC_RS06720	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
F126LOC_RS06720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F126LOC_RS06725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F126LOC_RS06735	COG0697	spore germination
F126LOC_RS06740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F126LOC_RS06745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F126LOC_RS06750	COG0101	tRNA pseudouridine synthase activity
F126LOC_RS06755	COG0586	Pfam SNARE associated Golgi protein
F126LOC_RS06760	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
F126LOC_RS06765	COG0285	dihydrofolate synthase activity
F126LOC_RS06770	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
F126LOC_RS06775	COG1286	toxin biosynthetic process
F126LOC_RS06780	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F126LOC_RS06785	COG0163	prenyltransferase activity
F126LOC_RS06800	COG4160	amino acid transport
F126LOC_RS06805	COG4598	ABC transporter
F126LOC_RS06810	COG1090	epimerase
F126LOC_RS06815	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F126LOC_RS06820	COG0625	glutathione transferase activity
F126LOC_RS06825	COG0622	Phosphoesterase
F126LOC_RS06830	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
F126LOC_RS06835	COG3739	integral membrane protein
F126LOC_RS06840	COG0857	belongs to the CobB CobQ family
F126LOC_RS06840	COG0280	phosphate acetyltransferase
F126LOC_RS06845	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F126LOC_RS06850	COG3092	negative regulation of chromosome organization
F126LOC_RS06855	COG3013	Belongs to the UPF0304 family
F126LOC_RS06860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F126LOC_RS06865	COG0471	metal ion transport
F126LOC_RS06865	COG0490	domain, Protein
F126LOC_RS06870	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
F126LOC_RS06875	COG0436	Aminotransferase
F126LOC_RS06880	COG0583	DNA-binding transcription factor activity
F126LOC_RS06890	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F126LOC_RS06895	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F126LOC_RS06895	COG0649	NAD binding
F126LOC_RS06900	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F126LOC_RS06915	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
F126LOC_RS06920	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F126LOC_RS06925	COG0839	Belongs to the complex I subunit 6 family
F126LOC_RS06930	COG0713	ATP synthesis coupled electron transport
F126LOC_RS06935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F126LOC_RS06940	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F126LOC_RS06945	COG1007	ATP synthesis coupled electron transport
F126LOC_RS06950	COG4575	ribosome binding
F126LOC_RS06955	COG0366	Alpha amylase catalytic
F126LOC_RS06960	COG1263	PTS System
F126LOC_RS06960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F126LOC_RS06965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F126LOC_RS06975	COG0488	(ABC) transporter
F126LOC_RS06985	COG4771	TonB-dependent receptor
F126LOC_RS07010	COG4993	Dehydrogenase
F126LOC_RS07020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F126LOC_RS07025	COG3058	Necessary for formate dehydrogenase activity
F126LOC_RS07035	COG2149	membrane
F126LOC_RS07040	COG4890	Cyd operon protein YbgT
F126LOC_RS07045	COG1294	oxidase, subunit
F126LOC_RS07050	COG1271	oxidase subunit
F126LOC_RS07065	COG3707	response regulator
F126LOC_RS07070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F126LOC_RS07080	COG1116	anion transmembrane transporter activity
F126LOC_RS07085	COG2146	nitrite reductase [NAD(P)H] activity
F126LOC_RS07085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F126LOC_RS07090	COG0243	molybdopterin cofactor binding
F126LOC_RS07095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F126LOC_RS07095	COG1648	precorrin-2 dehydrogenase activity
F126LOC_RS07100	COG5464	transposase or invertase
F126LOC_RS07105	COG4807	Protein conserved in bacteria
F126LOC_RS07110	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
F126LOC_RS07120	COG1129	ABC transporter
F126LOC_RS07125	COG1172	Belongs to the binding-protein-dependent transport system permease family
F126LOC_RS07130	COG1172	Belongs to the binding-protein-dependent transport system permease family
F126LOC_RS07140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F126LOC_RS07145	COG1070	Carbohydrate kinase
F126LOC_RS07150	COG0640	Transcriptional regulator
F126LOC_RS07155	COG1902	pentaerythritol trinitrate reductase activity
F126LOC_RS07165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F126LOC_RS07170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F126LOC_RS07175	COG0745	RESPONSE REGULATOR receiver
F126LOC_RS07180	COG2205	protein histidine kinase activity
F126LOC_RS07215	COG2826	transposase and inactivated derivatives, IS30 family
F126LOC_RS07225	COG0745	RESPONSE REGULATOR receiver
F126LOC_RS07265	COG2826	transposase and inactivated derivatives, IS30 family
F126LOC_RS07285	COG0765	amino acid transport
F126LOC_RS07290	COG0765	amino acid transport
F126LOC_RS07305	COG5002	protein histidine kinase activity
F126LOC_RS07305	COG5000	phosphorelay sensor kinase activity
F126LOC_RS07310	COG0745	RESPONSE REGULATOR receiver
F126LOC_RS07330	COG4948	Mandelate Racemase Muconate Lactonizing
F126LOC_RS07340	COG0659	secondary active sulfate transmembrane transporter activity
F126LOC_RS07345	COG0481	GTPase activity
F126LOC_RS07350	COG2951	lytic endotransglycosylase activity
F126LOC_RS07370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F126LOC_RS07375	COG2814	Major facilitator Superfamily
F126LOC_RS07400	COG1113	amino acid transport
F126LOC_RS07420	COG2197	response regulator
F126LOC_RS07425	COG0322	excinuclease ABC activity
F126LOC_RS07430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F126LOC_RS07485	COG3706	GGDEF domain
F126LOC_RS07495	COG0840	transmembrane signaling receptor activity
F126LOC_RS07500	COG0697	spore germination
F126LOC_RS07525	COG2198	Histidine kinase
F126LOC_RS07525	COG0643	Histidine kinase
F126LOC_RS07530	COG0835	chemotaxis
F126LOC_RS07535	COG0840	transmembrane signaling receptor activity
F126LOC_RS07540	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F126LOC_RS07545	COG2201	protein-glutamate methylesterase activity
F126LOC_RS07550	COG0745	RESPONSE REGULATOR receiver
F126LOC_RS07560	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F126LOC_RS07565	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F126LOC_RS07580	COG2747	anti-sigma28 factor FlgM
F126LOC_RS07590	COG1815	bacterial-type flagellum-dependent cell motility
F126LOC_RS07595	COG1558	bacterial-type flagellum-dependent cell motility
F126LOC_RS07600	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
F126LOC_RS07605	COG1749	Flagellar hook protein flgE
F126LOC_RS07610	COG4787	bacterial-type flagellum-dependent cell motility
F126LOC_RS07620	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
F126LOC_RS07625	COG1706	bacterial-type flagellum-dependent cell motility
F126LOC_RS07675	COG1580	Controls the rotational direction of flagella during chemotaxis
F126LOC_RS07695	COG1317	bacterial-type flagellum organization
F126LOC_RS07710	COG1677	Flagellar hook-basal body complex protein FliE
F126LOC_RS07735	COG0500	methyltransferase
F126LOC_RS07775	COG1191	sigma factor activity
F126LOC_RS07785	COG1702	phosphate starvation-inducible protein PhoH
F126LOC_RS07800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F126LOC_RS07805	COG1309	transcriptional regulator
F126LOC_RS07810	COG1012	belongs to the aldehyde dehydrogenase family
F126LOC_RS07815	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
F126LOC_RS07820	COG2979	Protein of unknown function (DUF533)
F126LOC_RS07825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F126LOC_RS07830	COG1067	ATP-dependent peptidase activity
F126LOC_RS07845	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
F126LOC_RS07850	COG3070	regulator of competence-specific genes
F126LOC_RS07855	COG1289	transmembrane transporter activity
F126LOC_RS07860	COG3304	Inner membrane component domain
F126LOC_RS07865	COG0210	DNA helicase
F126LOC_RS07870	COG1803	Methylglyoxal synthase
F126LOC_RS07880	COG1832	CoA-binding protein
F126LOC_RS07885	COG3785	DNA binding
F126LOC_RS07890	COG1254	Belongs to the acylphosphatase family
F126LOC_RS07895	COG2920	part of a sulfur-relay system
F126LOC_RS07900	COG0670	Belongs to the BI1 family
F126LOC_RS07930	COG0589	response to stress
F126LOC_RS07950	COG0840	transmembrane signaling receptor activity
F126LOC_RS07965	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
F126LOC_RS07970	COG2943	transferase activity, transferring hexosyl groups
F126LOC_RS07975	COG1560	Kdo2-lipid A biosynthetic process
F126LOC_RS07980	COG1902	pentaerythritol trinitrate reductase activity
F126LOC_RS07985	COG1054	Belongs to the UPF0176 family
F126LOC_RS07990	COG2353	YceI-like domain
F126LOC_RS07995	COG3038	cytochrome b561
F126LOC_RS08015	COG0418	dihydroorotase activity
F126LOC_RS08025	COG1530	ribonuclease E activity
F126LOC_RS08025	COG1530	ribonuclease E activity
F126LOC_RS08030	COG0564	pseudouridine synthase activity
F126LOC_RS08035	COG0424	maF-like protein
F126LOC_RS08040	COG1399	metal-binding, possibly nucleic acid-binding protein
F126LOC_RS08045	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F126LOC_RS08050	COG0416	fatty acid biosynthetic process
F126LOC_RS08055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F126LOC_RS08060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F126LOC_RS08070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F126LOC_RS08075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F126LOC_RS08080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F126LOC_RS08085	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F126LOC_RS08090	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
F126LOC_RS08095	COG0470	DNA polymerase III
F126LOC_RS08100	COG0084	hydrolase, TatD family'
F126LOC_RS08105	COG1263	PTS System
F126LOC_RS08105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F126LOC_RS08115	COG0477	Major facilitator Superfamily
F126LOC_RS08120	COG0537	adenosine 5'-monophosphoramidase activity
F126LOC_RS08130	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
F126LOC_RS08140	COG1472	Belongs to the glycosyl hydrolase 3 family
F126LOC_RS08145	COG3150	esterase
F126LOC_RS08150	COG1252	NADH dehydrogenase
F126LOC_RS08155	COG3134	Outer membrane lipoprotein
F126LOC_RS08160	COG2814	Major facilitator Superfamily
F126LOC_RS08170	COG1309	transcriptional regulator
F126LOC_RS08175	COG0443	Heat shock 70 kDa protein
F126LOC_RS08180	COG3547	Transposase (IS116 IS110 IS902 family)
F126LOC_RS08185	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F126LOC_RS08190	COG4591	ABC-type transport system involved in lipoprotein release permease component
F126LOC_RS08195	COG1136	(ABC) transporter
F126LOC_RS08200	COG4591	ABC-type transport system involved in lipoprotein release permease component
F126LOC_RS08205	COG1940	carbohydrate kinase activity
F126LOC_RS08215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F126LOC_RS08225	COG2226	methyltransferase
F126LOC_RS08230	COG4139	cobalamin transport
F126LOC_RS08235	COG0386	Belongs to the glutathione peroxidase family
F126LOC_RS08240	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
F126LOC_RS08245	COG0791	NLP P60 protein
F126LOC_RS08250	COG0095	Lipoate-protein ligase
F126LOC_RS08255	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F126LOC_RS08260	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F126LOC_RS08265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F126LOC_RS08270	COG4558	Periplasmic binding protein
F126LOC_RS08275	COG3720	iron ion transport
F126LOC_RS08280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F126LOC_RS08285	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
F126LOC_RS08290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F126LOC_RS08290	COG0574	Belongs to the PEP-utilizing enzyme family
F126LOC_RS08305	COG1477	protein flavinylation
F126LOC_RS08315	COG0628	permease
F126LOC_RS08320	COG0247	lactate metabolic process
F126LOC_RS08320	COG0277	FAD linked oxidase domain protein
F126LOC_RS08325	COG2050	protein possibly involved in aromatic compounds catabolism
F126LOC_RS08335	COG0316	Belongs to the HesB IscA family
F126LOC_RS08340	COG0719	Fe-S assembly protein
F126LOC_RS08345	COG0396	ATPase activity
F126LOC_RS08350	COG0719	Fe-S assembly protein
F126LOC_RS08355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F126LOC_RS08360	COG2166	iron-sulfur cluster assembly
F126LOC_RS08365	COG1388	LysM domain
F126LOC_RS08365	COG1376	ErfK ybiS ycfS ynhG family protein
F126LOC_RS08370	COG4238	major outer membrane lipoprotein
F126LOC_RS08400	COG2382	esterase
F126LOC_RS08410	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
F126LOC_RS08415	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
F126LOC_RS08420	COG0437	4 iron, 4 sulfur cluster binding
F126LOC_RS08425	COG3301	Polysulphide reductase, NrfD
F126LOC_RS08430	COG1138	Cytochrome C-type biogenesis protein
F126LOC_RS08435	COG3088	subunit of a heme lyase
F126LOC_RS08440	COG4235	cytochrome complex assembly
F126LOC_RS08445	COG4133	protoheme IX ABC transporter activity
F126LOC_RS08450	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F126LOC_RS08455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F126LOC_RS08460	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F126LOC_RS08465	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
F126LOC_RS08470	COG1138	Cytochrome C-type biogenesis protein
F126LOC_RS08475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F126LOC_RS08480	COG4235	cytochrome complex assembly
F126LOC_RS08480	COG3088	subunit of a heme lyase
F126LOC_RS08485	COG4235	cytochrome complex assembly
F126LOC_RS08485	COG3088	subunit of a heme lyase
F126LOC_RS08490	COG3547	Transposase (IS116 IS110 IS902 family)
F126LOC_RS08495	COG3005	denitrification pathway
F126LOC_RS08500	COG3043	anaerobic respiration
F126LOC_RS08505	COG0348	domain, Protein
F126LOC_RS08510	COG0437	4 iron, 4 sulfur cluster binding
F126LOC_RS08515	COG0243	molybdopterin cofactor binding
F126LOC_RS08520	COG3062	negative regulation of establishment of protein localization
F126LOC_RS08525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F126LOC_RS08525	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
F126LOC_RS08530	COG3850	Histidine kinase
F126LOC_RS08535	COG2197	response regulator
F126LOC_RS08570	COG2076	Multidrug Resistance protein
F126LOC_RS08575	COG0561	phosphatase activity
F126LOC_RS08585	COG1408	metallophosphoesterase
F126LOC_RS08590	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
F126LOC_RS08610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F126LOC_RS08615	COG1116	anion transmembrane transporter activity
F126LOC_RS08620	COG3665	Urea carboxylase-associated protein
F126LOC_RS08635	COG4770	biotin carboxylase activity
F126LOC_RS08645	COG0534	Mate efflux family protein
F126LOC_RS08650	COG0307	riboflavin synthase, alpha
F126LOC_RS08655	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F126LOC_RS08660	COG1609	Transcriptional regulator
F126LOC_RS08670	COG0791	NLP P60 protein
F126LOC_RS08675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F126LOC_RS08680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F126LOC_RS08685	COG0346	lactoylglutathione lyase activity
F126LOC_RS08690	COG3313	Fe-S protein
F126LOC_RS08705	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F126LOC_RS08710	COG3895	Periplasmic Protein
F126LOC_RS08715	COG0259	pyridoxamine-phosphate oxidase activity
F126LOC_RS08720	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F126LOC_RS08725	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
F126LOC_RS08730	COG0625	glutathione transferase activity
F126LOC_RS08735	COG1301	dicarboxylic acid transport
F126LOC_RS08740	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F126LOC_RS08760	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F126LOC_RS08765	COG0671	phosphoesterase, PA-phosphatase related
F126LOC_RS08770	COG1879	ABC-type sugar transport system periplasmic component
F126LOC_RS08780	COG1129	ABC transporter
F126LOC_RS08785	COG1172	Belongs to the binding-protein-dependent transport system permease family
F126LOC_RS08790	COG3959	Transketolase, thiamine diphosphate binding domain
F126LOC_RS08795	COG3958	Transketolase
F126LOC_RS08800	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F126LOC_RS08805	COG1082	Xylose isomerase domain protein TIM barrel
F126LOC_RS08815	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
F126LOC_RS08820	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
F126LOC_RS08825	COG0284	orotidine-5'-phosphate decarboxylase activity
F126LOC_RS08830	COG0023	Translation Initiation Factor
F126LOC_RS08840	COG0235	Class ii aldolase
F126LOC_RS08845	COG1966	Carbon starvation protein
F126LOC_RS08850	COG4989	oxidoreductase activity
F126LOC_RS08855	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
F126LOC_RS08860	COG0243	molybdopterin cofactor binding
F126LOC_RS08865	COG0583	DNA-binding transcription factor activity
F126LOC_RS08875	COG2271	Major facilitator Superfamily
F126LOC_RS08915	COG4171	peptide transport system, permease
F126LOC_RS08925	COG4166	transmembrane transport
F126LOC_RS08945	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F126LOC_RS08950	COG1842	Phage shock protein A
F126LOC_RS08960	COG1983	PspC domain protein
F126LOC_RS08975	COG3210	domain, Protein
F126LOC_RS08985	COG2831	hemolysin activation secretion protein
F126LOC_RS08990	COG3106	COG3106 Predicted ATPase
F126LOC_RS08995	COG3768	UPF0283 membrane protein
F126LOC_RS09010	COG0514	ATP-dependent DNA helicase (RecQ)
F126LOC_RS09030	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F126LOC_RS09035	COG2866	Carboxypeptidase
F126LOC_RS09040	COG4166	transmembrane transport
F126LOC_RS09045	COG0598	Magnesium transport protein CorA
F126LOC_RS09055	COG0037	tRNA processing
F126LOC_RS09085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F126LOC_RS09090	COG0840	transmembrane signaling receptor activity
F126LOC_RS09095	COG0840	transmembrane signaling receptor activity
F126LOC_RS09100	COG2911	Protein conserved in bacteria
F126LOC_RS09110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F126LOC_RS09115	COG1643	Atp-dependent helicase
F126LOC_RS09125	COG5001	Diguanylate cyclase
F126LOC_RS09125	COG3300	MHYT domain
F126LOC_RS09130	COG3591	Belongs to the peptidase S1B family
F126LOC_RS09145	COG2205	protein histidine kinase activity
F126LOC_RS09150	COG0745	RESPONSE REGULATOR receiver
F126LOC_RS09180	COG1028	Short-chain dehydrogenase reductase Sdr
F126LOC_RS09190	COG0659	secondary active sulfate transmembrane transporter activity
F126LOC_RS09195	COG0387	Pfam Sodium calcium exchanger
F126LOC_RS09205	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
F126LOC_RS09220	COG2197	response regulator
F126LOC_RS09225	COG3850	Histidine kinase
F126LOC_RS09230	COG2223	nitrite transmembrane transporter activity
F126LOC_RS09235	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F126LOC_RS09240	COG1140	nitrate reductase beta subunit
F126LOC_RS09245	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F126LOC_RS09250	COG2181	nitrate reductase activity
F126LOC_RS09255	COG0697	spore germination
F126LOC_RS09260	COG1846	Transcriptional regulator
F126LOC_RS09275	COG2423	ornithine cyclodeaminase activity
F126LOC_RS09290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F126LOC_RS09295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F126LOC_RS09300	COG0322	excinuclease ABC activity
F126LOC_RS09305	COG2261	transglycosylase associated protein
F126LOC_RS09340	COG3842	ATPase activity
F126LOC_RS09350	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F126LOC_RS09355	COG1012	belongs to the aldehyde dehydrogenase family
F126LOC_RS09365	COG1176	ABC-type spermidine putrescine transport system, permease component I
F126LOC_RS09375	COG1028	Short-chain dehydrogenase reductase Sdr
F126LOC_RS09385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F126LOC_RS09395	COG0671	phosphoesterase, PA-phosphatase related
F126LOC_RS09400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F126LOC_RS09405	COG2011	ABC-type metal ion transport system permease component
F126LOC_RS09410	COG4948	Mandelate Racemase Muconate Lactonizing
F126LOC_RS09415	COG1464	Belongs to the NlpA lipoprotein family
F126LOC_RS09435	COG0583	DNA-binding transcription factor activity
F126LOC_RS09440	COG4792	protein secretion
F126LOC_RS09450	COG4794	Type iii secretion
F126LOC_RS09475	COG1157	protein secretion by the type III secretion system
F126LOC_RS09500	COG3850	Histidine kinase
F126LOC_RS09505	COG2197	response regulator
F126LOC_RS09515	COG2200	EAL domain
F126LOC_RS09530	COG4669	(LipO)protein
F126LOC_RS09575	COG3501	Rhs element vgr protein
F126LOC_RS09625	COG1802	Transcriptional regulator
F126LOC_RS09630	COG2831	hemolysin activation secretion protein
F126LOC_RS09635	COG3210	domain, Protein
F126LOC_RS09695	COG2211	Major facilitator Superfamily
F126LOC_RS09700	COG3507	Belongs to the glycosyl hydrolase 43 family
F126LOC_RS09715	COG1802	Transcriptional regulator
F126LOC_RS09735	COG1129	ABC transporter
F126LOC_RS09755	COG2314	TM2 domain
F126LOC_RS09765	COG1126	abc transporter atp-binding protein
F126LOC_RS09770	COG0765	amino acid transport
F126LOC_RS09780	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
F126LOC_RS09790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F126LOC_RS09800	COG1473	amidohydrolase
F126LOC_RS09805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F126LOC_RS09820	COG2234	aminopeptidase activity
F126LOC_RS09825	COG2826	transposase and inactivated derivatives, IS30 family
F126LOC_RS09830	COG1609	Transcriptional regulator
F126LOC_RS09835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F126LOC_RS09835	COG1263	PTS System
F126LOC_RS09840	COG2723	6-phospho-beta-galactosidase activity
F126LOC_RS09845	COG0483	inositol monophosphate 1-phosphatase activity
F126LOC_RS09850	COG0346	lactoylglutathione lyase activity
F126LOC_RS09855	COG3443	Belongs to the bacterial solute-binding protein 9 family
F126LOC_RS09860	COG0523	cobalamin synthesis protein
F126LOC_RS09865	COG2755	lipolytic protein G-D-S-L family
F126LOC_RS09880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F126LOC_RS09915	COG3958	Transketolase
F126LOC_RS09920	COG3959	Transketolase, thiamine diphosphate binding domain
F126LOC_RS09925	COG1028	Short-chain dehydrogenase reductase Sdr
F126LOC_RS09930	COG2271	Major facilitator Superfamily
F126LOC_RS09935	COG0583	DNA-binding transcription factor activity
F126LOC_RS09940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F126LOC_RS09950	COG0012	GTP binding
F126LOC_RS09955	COG0193	aminoacyl-tRNA hydrolase activity
F126LOC_RS09965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F126LOC_RS09970	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
F126LOC_RS09975	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
F126LOC_RS09980	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
F126LOC_RS09985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F126LOC_RS09990	COG2890	protein-(glutamine-N5) methyltransferase activity
F126LOC_RS10000	COG2912	Transglutaminase-like superfamily
F126LOC_RS10005	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F126LOC_RS10015	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F126LOC_RS10020	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F126LOC_RS10030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F126LOC_RS10035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F126LOC_RS10040	COG0673	inositol 2-dehydrogenase activity
F126LOC_RS10055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F126LOC_RS10085	COG4305	rare lipoprotein A
F126LOC_RS10090	COG1764	response to oxidative stress
F126LOC_RS10095	COG3783	Cytochrome b(562)
F126LOC_RS10105	COG0738	Major facilitator superfamily
F126LOC_RS10110	COG0456	acetyltransferase
F126LOC_RS10185	COG5290	Psort location Cytoplasmic, score
F126LOC_RS10270	COG4628	conserved protein (DUF2132)
F126LOC_RS10275	COG1649	PFAM Uncharacterised BCR, COG1649
F126LOC_RS10285	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F126LOC_RS10290	COG0076	glutamate decarboxylase activity
F126LOC_RS10295	COG0697	spore germination
F126LOC_RS10300	COG1942	4-Oxalocrotonate Tautomerase
F126LOC_RS10315	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F126LOC_RS10330	COG1215	transferase activity, transferring glycosyl groups
F126LOC_RS10335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F126LOC_RS10340	COG4221	oxidoreductase activity
F126LOC_RS10360	COG0477	Major facilitator Superfamily
F126LOC_RS10365	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F126LOC_RS10370	COG1940	carbohydrate kinase activity
F126LOC_RS10375	COG0583	DNA-binding transcription factor activity
F126LOC_RS10380	COG2814	Major facilitator Superfamily
F126LOC_RS10390	COG0114	fumarate hydratase activity
F126LOC_RS10395	COG1482	cell wall glycoprotein biosynthetic process
F126LOC_RS10400	COG5339	Protein conserved in bacteria
F126LOC_RS10410	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F126LOC_RS10420	COG0385	Bile acid
F126LOC_RS10425	COG0673	inositol 2-dehydrogenase activity
F126LOC_RS10435	COG1172	Belongs to the binding-protein-dependent transport system permease family
F126LOC_RS10440	COG1129	ABC transporter
F126LOC_RS10445	COG1879	ABC-type sugar transport system periplasmic component
F126LOC_RS10450	COG1069	ribulokinase activity
F126LOC_RS10455	COG2160	L-arabinose isomerase activity
F126LOC_RS10465	COG4657	Part of a membrane complex involved in electron transport
F126LOC_RS10470	COG2878	Part of a membrane complex involved in electron transport
F126LOC_RS10475	COG4656	Part of a membrane complex involved in electron transport
F126LOC_RS10480	COG4658	electron transport chain
F126LOC_RS10485	COG4659	FMN binding
F126LOC_RS10495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F126LOC_RS10500	COG3104	oligopeptide transport
F126LOC_RS10520	COG0616	signal peptide processing
F126LOC_RS10525	COG1028	Short-chain dehydrogenase reductase Sdr
F126LOC_RS10530	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
F126LOC_RS10535	COG1187	pseudouridine synthase activity
F126LOC_RS10540	COG0009	L-threonylcarbamoyladenylate synthase
F126LOC_RS10545	COG0613	PHP domain protein
F126LOC_RS10565	COG0512	Glutamine amidotransferase of anthranilate synthase
F126LOC_RS10570	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F126LOC_RS10575	COG0135	phosphoribosylanthranilate isomerase activity
F126LOC_RS10575	COG0134	indole-3-glycerol-phosphate synthase activity
F126LOC_RS10580	COG0133	tryptophan synthase activity
F126LOC_RS10585	COG0159	tryptophan synthase activity
F126LOC_RS10590	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F126LOC_RS10595	COG3047	cAMP biosynthetic process
F126LOC_RS10605	COG2917	probably involved in intracellular septation
F126LOC_RS10610	COG1607	acyl-coa hydrolase
F126LOC_RS10620	COG2350	Protein conserved in bacteria
F126LOC_RS10635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F126LOC_RS10640	COG3099	Belongs to the UPF0263 family
F126LOC_RS10650	COG0444	Belongs to the ABC transporter superfamily
F126LOC_RS10655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F126LOC_RS10660	COG0601	transmembrane transport
F126LOC_RS10675	COG1454	alcohol dehydrogenase
F126LOC_RS10675	COG1012	belongs to the aldehyde dehydrogenase family
F126LOC_RS10680	COG1435	thymidine kinase activity
F126LOC_RS10690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F126LOC_RS10695	COG0745	RESPONSE REGULATOR receiver
F126LOC_RS10700	COG1752	Esterase of the alpha-beta hydrolase superfamily
F126LOC_RS10705	COG3012	SEC-C Motif Domain Protein
F126LOC_RS10710	COG0788	formyltetrahydrofolate deformylase activity
F126LOC_RS10720	COG2860	membrane
F126LOC_RS10725	COG0708	Exodeoxyribonuclease III
F126LOC_RS10735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F126LOC_RS10740	COG0778	Nitroreductase
F126LOC_RS10745	COG0616	signal peptide processing
F126LOC_RS10750	COG0252	asparaginase activity
F126LOC_RS10755	COG1335	isochorismatase
F126LOC_RS10760	COG3139	Protein of unknown function (DUF1315)
F126LOC_RS10765	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F126LOC_RS10780	COG0656	L-ascorbic acid biosynthetic process
F126LOC_RS10785	COG3713	MltA-interacting MipA family protein
F126LOC_RS10790	COG2766	serine protein kinase
F126LOC_RS10795	COG2718	Belongs to the UPF0229 family
F126LOC_RS10810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F126LOC_RS10815	COG0205	6-phosphofructokinase activity
F126LOC_RS10835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F126LOC_RS10845	COG3684	Belongs to the aldolase LacD family
F126LOC_RS10850	COG2719	SpoVR family
F126LOC_RS10855	COG2186	Transcriptional regulator
F126LOC_RS10860	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F126LOC_RS10865	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F126LOC_RS10875	COG2983	Belongs to the UPF0260 family
F126LOC_RS10880	COG0179	Fumarylacetoacetate (FAA) hydrolase
F126LOC_RS10885	COG3100	YcgL domain-containing protein
F126LOC_RS10890	COG0850	regulation of cytokinetic process
F126LOC_RS10895	COG2894	cell division
F126LOC_RS10900	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
F126LOC_RS10905	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F126LOC_RS10910	COG0318	PFAM AMP-dependent synthetase and ligase
F126LOC_RS10915	COG3065	identical protein binding
F126LOC_RS10925	COG1199	ATP-dependent helicase activity
F126LOC_RS10930	COG0251	oxidation-reduction process
F126LOC_RS10935	COG3140	Belongs to the UPF0181 family
F126LOC_RS10945	COG0494	nUDIX hydrolase
F126LOC_RS10950	COG1760	l-serine dehydratase
F126LOC_RS10970	COG1253	flavin adenine dinucleotide binding
F126LOC_RS10975	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F126LOC_RS10975	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F126LOC_RS10980	COG3715	PTS system
F126LOC_RS10985	COG3716	PTS system mannose fructose sorbose family IID component
F126LOC_RS10990	COG4811	Protein of unknown function (DUF986)
F126LOC_RS10995	COG1971	Probably functions as a manganese efflux pump
F126LOC_RS11000	COG2226	methyltransferase
F126LOC_RS11015	COG0803	Belongs to the bacterial solute-binding protein 9 family
F126LOC_RS11020	COG1121	(ABC) transporter
F126LOC_RS11025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F126LOC_RS11030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F126LOC_RS11035	COG3001	Fructosamine kinase
F126LOC_RS11045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F126LOC_RS11050	COG1917	Cupin 2, conserved barrel domain protein
F126LOC_RS11055	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
F126LOC_RS11060	COG1028	Short-chain dehydrogenase reductase Sdr
F126LOC_RS11070	COG1175	transmembrane transport
F126LOC_RS11075	COG0395	ABC-type sugar transport system, permease component
F126LOC_RS11080	COG3842	ATPase activity
F126LOC_RS11090	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F126LOC_RS11095	COG2755	lipolytic protein G-D-S-L family
F126LOC_RS11095	COG0657	acetylesterase activity
F126LOC_RS11100	COG1988	membrane-bound metal-dependent
F126LOC_RS11105	COG1823	symporter activity
F126LOC_RS11110	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F126LOC_RS11115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F126LOC_RS11125	COG1132	(ABC) transporter
F126LOC_RS11135	COG0776	regulation of translation
F126LOC_RS11140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F126LOC_RS11140	COG0072	phenylalanine-tRNA ligase activity
F126LOC_RS11145	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F126LOC_RS11155	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F126LOC_RS11160	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F126LOC_RS11165	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F126LOC_RS11170	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F126LOC_RS11175	COG1113	amino acid transport
F126LOC_RS11190	COG0823	Involved in the tonB-independent uptake of proteins
F126LOC_RS11195	COG0501	Belongs to the peptidase M48B family
F126LOC_RS11205	COG1653	transport
F126LOC_RS11210	COG2223	nitrite transmembrane transporter activity
F126LOC_RS11215	COG3279	Response regulator of the LytR AlgR family
F126LOC_RS11220	COG3275	phosphorelay sensor kinase activity
F126LOC_RS11245	COG0348	domain, Protein
F126LOC_RS11250	COG0538	isocitrate dehydrogenase activity
F126LOC_RS11255	COG1187	pseudouridine synthase activity
F126LOC_RS11265	COG0482	sulfurtransferase activity
F126LOC_RS11270	COG2915	High frequency lysogenization protein hflD homolog
F126LOC_RS11275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F126LOC_RS11290	COG2850	peptidyl-arginine hydroxylation
F126LOC_RS11295	COG2195	Cleaves the N-terminal amino acid of tripeptides
F126LOC_RS11300	COG3842	ATPase activity
F126LOC_RS11310	COG1177	transmembrane transport
F126LOC_RS11325	COG2223	nitrite transmembrane transporter activity
F126LOC_RS11340	COG2207	Transcriptional regulator
F126LOC_RS11350	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
F126LOC_RS11355	COG1956	GAF domain-containing protein
F126LOC_RS11360	COG2995	paraquat-inducible protein a
F126LOC_RS11365	COG3008	intermembrane lipid transfer
F126LOC_RS11370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F126LOC_RS11370	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
F126LOC_RS11385	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F126LOC_RS11405	COG1278	Cold shock
F126LOC_RS11415	COG1528	Iron-storage protein
F126LOC_RS11425	COG1770	oligopeptidase
F126LOC_RS11430	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
F126LOC_RS11435	COG0800	Aldolase
F126LOC_RS11440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F126LOC_RS11445	COG1737	Transcriptional regulator
F126LOC_RS11450	COG0469	pyruvate kinase activity
F126LOC_RS11455	COG1560	Kdo2-lipid A biosynthetic process
F126LOC_RS11460	COG0739	heme binding
F126LOC_RS11465	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
F126LOC_RS11470	COG1121	(ABC) transporter
F126LOC_RS11475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F126LOC_RS11480	COG1609	Transcriptional regulator
F126LOC_RS11485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F126LOC_RS11490	COG1447	Phosphotransferase system cellobiose-specific component IIA
F126LOC_RS11495	COG4580	involved in the transport of maltose and maltodextrins
F126LOC_RS11500	COG2255	four-way junction helicase activity
F126LOC_RS11505	COG0632	four-way junction helicase activity
F126LOC_RS11510	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
F126LOC_RS11515	COG0217	transcriptional regulatory protein
F126LOC_RS11520	COG0494	nUDIX hydrolase
F126LOC_RS11525	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F126LOC_RS11530	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
F126LOC_RS11535	COG1801	Protein of unknown function DUF72
F126LOC_RS11540	COG3788	relative of glutathione S-transferase, MAPEG superfamily
F126LOC_RS11545	COG2226	methyltransferase
F126LOC_RS11550	COG0500	methyltransferase
F126LOC_RS11555	COG3142	Participates in the control of copper homeostasis
F126LOC_RS11560	COG3102	Protein conserved in bacteria
F126LOC_RS11565	COG0018	arginyl-trna synthetase
F126LOC_RS11570	COG0728	peptidoglycan biosynthetic process
F126LOC_RS11580	COG3132	Protein of unknown function, DUF480
F126LOC_RS11585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F126LOC_RS11590	COG0477	Major facilitator Superfamily
F126LOC_RS11595	COG2999	glutathione oxidoreductase activity
F126LOC_RS11605	COG3381	protein complex oligomerization
F126LOC_RS11610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
F126LOC_RS11625	COG0840	transmembrane signaling receptor activity
F126LOC_RS11630	COG3130	regulation of translation
F126LOC_RS11635	COG3009	Protein conserved in bacteria
F126LOC_RS11640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F126LOC_RS11640	COG3008	intermembrane lipid transfer
F126LOC_RS11645	COG2995	paraquat-inducible protein a
F126LOC_RS11650	COG0488	(ABC) transporter
F126LOC_RS11655	COG0116	Belongs to the methyltransferase superfamily
F126LOC_RS11655	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F126LOC_RS11660	COG3217	Mosc domain protein beta barrel domain protein
F126LOC_RS11660	COG0633	Ferredoxin
F126LOC_RS11670	COG0167	dihydroorotate dehydrogenase activity
F126LOC_RS11675	COG0308	aminopeptidase N
F126LOC_RS11680	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F126LOC_RS11685	COG0017	Asparaginyl-tRNA synthetase
F126LOC_RS11695	COG1448	Aminotransferase
F126LOC_RS11700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F126LOC_RS11705	COG3108	Peptidase M15
F126LOC_RS11710	COG2989	Protein conserved in bacteria
F126LOC_RS11715	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
F126LOC_RS11720	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
F126LOC_RS11725	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
F126LOC_RS11730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F126LOC_RS11735	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F126LOC_RS11740	COG3173	Aminoglycoside phosphotransferase
F126LOC_RS11750	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
F126LOC_RS11755	COG2835	tetraacyldisaccharide 4'-kinase activity
F126LOC_RS11760	COG1663	tetraacyldisaccharide 4'-kinase activity
F126LOC_RS11765	COG1132	(ABC) transporter
F126LOC_RS11770	COG2333	competence protein COMEC
F126LOC_RS11770	COG0658	competence protein
F126LOC_RS11775	COG2926	Belongs to the UPF0265 family
F126LOC_RS11780	COG4604	ABC transporter, ATP-binding protein
F126LOC_RS11785	COG4605	iron ion homeostasis
F126LOC_RS11795	COG4607	ABC-type enterochelin transport system periplasmic component
F126LOC_RS11800	COG2925	Exonuclease
F126LOC_RS11805	COG0531	amino acid
F126LOC_RS11810	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
F126LOC_RS11815	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
F126LOC_RS11835	COG3052	prosthetic group binding
F126LOC_RS11840	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
F126LOC_RS11845	COG0179	Fumarylacetoacetate (FAA) hydrolase
F126LOC_RS11850	COG3493	citrate carrier protein
F126LOC_RS11860	COG4565	transcriptional regulatory protein
F126LOC_RS11865	COG0840	transmembrane signaling receptor activity
F126LOC_RS11870	COG0840	transmembrane signaling receptor activity
F126LOC_RS11875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F126LOC_RS11885	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F126LOC_RS11890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F126LOC_RS11895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F126LOC_RS11900	COG0131	Imidazoleglycerol-phosphate dehydratase
F126LOC_RS11900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F126LOC_RS11905	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F126LOC_RS11910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F126LOC_RS11915	COG0107	imidazoleglycerol-phosphate synthase activity
F126LOC_RS11920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F126LOC_RS11920	COG0140	phosphoribosyl-ATP diphosphatase activity
F126LOC_RS11925	COG0776	regulation of translation
F126LOC_RS11930	COG0539	negative regulation of cytoplasmic translation
F126LOC_RS11935	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
F126LOC_RS11940	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F126LOC_RS11945	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
F126LOC_RS11950	COG1944	ATP diphosphatase activity
F126LOC_RS11955	COG2116	formate transmembrane transporter activity
F126LOC_RS11960	COG1882	Formate acetyltransferase
F126LOC_RS11965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F126LOC_RS11990	COG2814	Major facilitator Superfamily
F126LOC_RS11995	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F126LOC_RS12000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F126LOC_RS12005	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F126LOC_RS12010	COG3107	peptidoglycan biosynthetic process
F126LOC_RS12010	COG1674	ftsk spoiiie
F126LOC_RS12020	COG0492	ferredoxin-NADP+ reductase activity
F126LOC_RS12025	COG4988	ABC transporter
F126LOC_RS12030	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F126LOC_RS12035	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F126LOC_RS12040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F126LOC_RS12050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F126LOC_RS12055	COG0542	response to heat
F126LOC_RS12060	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F126LOC_RS12065	COG1278	Cold shock
F126LOC_RS12070	COG3593	DNA synthesis involved in DNA repair
F126LOC_RS12075	COG2431	L-lysine efflux transmembrane transporter activity
F126LOC_RS12080	COG1151	hydroxylamine reductase activity
F126LOC_RS12085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F126LOC_RS12090	COG0702	epimerase
F126LOC_RS12095	COG3023	N-Acetylmuramoyl-L-alanine amidase
F126LOC_RS12100	COG0393	Putative heavy-metal-binding
F126LOC_RS12105	COG1126	abc transporter atp-binding protein
F126LOC_RS12110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F126LOC_RS12115	COG4215	(ABC) transporter
F126LOC_RS12120	COG4160	amino acid transport
F126LOC_RS12125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F126LOC_RS12130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F126LOC_RS12140	COG1177	transmembrane transport
F126LOC_RS12145	COG1176	ABC-type spermidine putrescine transport system, permease component I
F126LOC_RS12150	COG3842	ATPase activity
F126LOC_RS12155	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F126LOC_RS12165	COG0189	ligase activity
F126LOC_RS12170	COG0778	Nitroreductase
F126LOC_RS12185	COG2985	domain, Protein
F126LOC_RS12185	COG0569	domain protein
F126LOC_RS12190	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
F126LOC_RS12195	COG1349	DNA-binding transcription factor activity
F126LOC_RS12200	COG1686	Belongs to the peptidase S11 family
F126LOC_RS12205	COG2011	ABC-type metal ion transport system permease component
F126LOC_RS12210	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F126LOC_RS12220	COG0625	glutathione transferase activity
F126LOC_RS12225	COG2133	pyrroloquinoline quinone binding
F126LOC_RS12255	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
F126LOC_RS12270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F126LOC_RS12275	COG2949	membrane
F126LOC_RS12280	COG2311	Membrane
F126LOC_RS12285	COG0302	gtp cyclohydrolase
F126LOC_RS12290	COG0840	transmembrane signaling receptor activity
F126LOC_RS12295	COG0583	DNA-binding transcription factor activity
F126LOC_RS12320	COG0371	Dehydrogenase
F126LOC_RS12325	COG1129	ABC transporter
F126LOC_RS12330	COG1172	Belongs to the binding-protein-dependent transport system permease family
F126LOC_RS12335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F126LOC_RS12340	COG4771	TonB-dependent receptor
F126LOC_RS12345	COG0833	amino acid
F126LOC_RS12350	COG0583	DNA-binding transcription factor activity
F126LOC_RS12355	COG2855	membrane
F126LOC_RS12360	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
F126LOC_RS12365	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F126LOC_RS12365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F126LOC_RS12365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F126LOC_RS12370	COG1105	Belongs to the carbohydrate kinase PfkB family
F126LOC_RS12375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F126LOC_RS12375	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F126LOC_RS12390	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F126LOC_RS12395	COG0523	cobalamin synthesis protein
F126LOC_RS12400	COG0671	phosphoesterase, PA-phosphatase related
F126LOC_RS12405	COG0791	NLP P60 protein
F126LOC_RS12410	COG4166	transmembrane transport
F126LOC_RS12415	COG4174	ABC transporter (Permease)
F126LOC_RS12420	COG4239	(ABC) transporter, permease
F126LOC_RS12425	COG4172	Belongs to the ABC transporter superfamily
F126LOC_RS12435	COG2814	Major facilitator Superfamily
F126LOC_RS12450	COG1061	Type III restriction enzyme res subunit
F126LOC_RS12455	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
F126LOC_RS12465	COG3081	Nucleoid-associated protein
F126LOC_RS12470	COG3082	Protein of unknown function (DUF1414)
F126LOC_RS12475	COG3083	sulfuric ester hydrolase activity
F126LOC_RS12495	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F126LOC_RS12505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F126LOC_RS12510	COG0534	Mate efflux family protein
F126LOC_RS12515	COG2807	transmembrane transport
F126LOC_RS12520	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F126LOC_RS12530	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F126LOC_RS12530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
F126LOC_RS12535	COG0783	Belongs to the Dps family
F126LOC_RS12540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F126LOC_RS12545	COG0765	amino acid transport
F126LOC_RS12550	COG1126	abc transporter atp-binding protein
F126LOC_RS12560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F126LOC_RS12625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F126LOC_RS12715	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
F126LOC_RS12730	COG1686	Belongs to the peptidase S11 family
F126LOC_RS12755	COG2040	homocysteine
F126LOC_RS12760	COG0833	amino acid
F126LOC_RS12765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F126LOC_RS12770	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F126LOC_RS12775	COG0747	negative chemotaxis
F126LOC_RS12780	COG2195	Cleaves the N-terminal amino acid of tripeptides
F126LOC_RS12785	COG3708	Transcriptional regulator
F126LOC_RS12785	COG2207	Transcriptional regulator
F126LOC_RS12795	COG0513	Belongs to the DEAD box helicase family
F126LOC_RS12805	COG1120	ATPase activity
F126LOC_RS12810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F126LOC_RS12815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F126LOC_RS12820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F126LOC_RS12835	COG1131	(ABC) transporter
F126LOC_RS12840	COG0842	Transport permease protein
F126LOC_RS12845	COG0842	Transport permease protein
F126LOC_RS12850	COG0670	Belongs to the BI1 family
F126LOC_RS12855	COG0314	molybdopterin synthase activity
F126LOC_RS12860	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
F126LOC_RS12865	COG0315	cyclic pyranopterin monophosphate synthase activity
F126LOC_RS12870	COG0521	Mo-molybdopterin cofactor biosynthetic process
F126LOC_RS12875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F126LOC_RS12890	COG0556	nucleotide-excision repair
F126LOC_RS12910	COG3157	Type VI secretion system effector, Hcp
F126LOC_RS12915	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F126LOC_RS12920	COG2226	methyltransferase
F126LOC_RS12925	COG0156	8-amino-7-oxononanoate synthase activity
F126LOC_RS12930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F126LOC_RS12940	COG5297	Belongs to the glycosyl hydrolase family 6
F126LOC_RS12945	COG1380	Effector of murein hydrolase LrgA
F126LOC_RS12950	COG1346	cytolysis
F126LOC_RS12955	COG0295	cytidine deaminase activity
F126LOC_RS12960	COG0281	malic enzyme
F126LOC_RS12965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F126LOC_RS12970	COG0601	transmembrane transport
F126LOC_RS12975	COG0747	negative chemotaxis
F126LOC_RS12980	COG4172	Belongs to the ABC transporter superfamily
F126LOC_RS12985	COG0303	'Molybdopterin
F126LOC_RS12990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F126LOC_RS13010	COG0401	homolog of Blt101
F126LOC_RS13025	COG3228	Belongs to the MtfA family
F126LOC_RS13035	COG0582	viral genome integration into host DNA
F126LOC_RS13050	COG3423	Transcriptional regulator
F126LOC_RS13070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F126LOC_RS13125	COG3736	Type IV secretory pathway, component VirB8
F126LOC_RS13130	COG3504	Conjugal transfer protein
F126LOC_RS13140	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
F126LOC_RS13180	COG4227	nucleotidyltransferase activity
F126LOC_RS13195	COG1201	RNA secondary structure unwinding
F126LOC_RS13245	COG3272	Protein of unknown function (DUF1722)
F126LOC_RS13265	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F126LOC_RS13280	COG0300	oxidoreductase activity
F126LOC_RS13290	COG0789	Transcriptional regulator
F126LOC_RS13320	COG3122	Protein conserved in bacteria
F126LOC_RS13330	COG2723	6-phospho-beta-galactosidase activity
F126LOC_RS13335	COG0789	Transcriptional regulator
F126LOC_RS13335	COG4978	Transcriptional regulator
F126LOC_RS13340	COG2814	Major facilitator Superfamily
F126LOC_RS13345	COG0640	Transcriptional regulator
F126LOC_RS13350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F126LOC_RS13360	COG1733	regulation of RNA biosynthetic process
F126LOC_RS13365	COG2910	NAD(P)H-binding
F126LOC_RS13370	COG0625	glutathione transferase activity
F126LOC_RS13375	COG2814	Major facilitator Superfamily
F126LOC_RS13380	COG3226	Transcriptional regulator
F126LOC_RS13390	COG0835	chemotaxis
F126LOC_RS13390	COG0784	Response regulator, receiver
F126LOC_RS13405	COG2995	paraquat-inducible protein a
F126LOC_RS13410	COG3008	intermembrane lipid transfer
F126LOC_RS13410	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F126LOC_RS13430	COG1132	(ABC) transporter
F126LOC_RS13435	COG1132	(ABC) transporter
F126LOC_RS13435	COG2375	cellular response to nickel ion
F126LOC_RS13455	COG4771	TonB-dependent receptor
F126LOC_RS13475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F126LOC_RS13490	COG5464	transposase or invertase
F126LOC_RS13495	COG4172	Belongs to the ABC transporter superfamily
F126LOC_RS13510	COG0747	negative chemotaxis
F126LOC_RS13515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F126LOC_RS13520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F126LOC_RS13530	COG0477	Major facilitator Superfamily
F126LOC_RS13550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F126LOC_RS13555	COG1012	belongs to the aldehyde dehydrogenase family
F126LOC_RS13600	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F126LOC_RS13605	COG0371	Dehydrogenase
F126LOC_RS13610	COG1301	dicarboxylic acid transport
F126LOC_RS13625	COG0697	spore germination
F126LOC_RS13630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F126LOC_RS13635	COG0577	efflux transmembrane transporter activity
F126LOC_RS13635	COG1136	(ABC) transporter
F126LOC_RS13645	COG0577	efflux transmembrane transporter activity
F126LOC_RS13645	COG1136	(ABC) transporter
F126LOC_RS13660	COG0672	)-iron permease
F126LOC_RS13670	COG3383	formate dehydrogenase (NAD+) activity
F126LOC_RS13675	COG2851	Citrate transporter
F126LOC_RS13685	COG1301	dicarboxylic acid transport
F126LOC_RS13690	COG0583	DNA-binding transcription factor activity
F126LOC_RS13705	COG1464	Belongs to the NlpA lipoprotein family
F126LOC_RS13720	COG2271	Major facilitator Superfamily
F126LOC_RS13725	COG1840	ABC-type Fe3 transport system, periplasmic component
F126LOC_RS13735	COG3842	ATPase activity
F126LOC_RS13740	COG3547	Transposase (IS116 IS110 IS902 family)
F126LOC_RS13745	COG1609	Transcriptional regulator
F126LOC_RS13750	COG3250	beta-galactosidase activity
F126LOC_RS13755	COG2223	nitrite transmembrane transporter activity
F126LOC_RS13790	COG2910	NAD(P)H-binding
F126LOC_RS13795	COG0583	DNA-binding transcription factor activity
F126LOC_RS13805	COG0583	DNA-binding transcription factor activity
F126LOC_RS13815	COG3615	Tellurite resistance protein tehB
F126LOC_RS13825	COG2203	Gaf domain
F126LOC_RS13825	COG2199	diguanylate cyclase activity
F126LOC_RS13830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F126LOC_RS13830	COG1263	PTS System
F126LOC_RS13830	COG2190	(PTS) system
F126LOC_RS13835	COG2723	6-phospho-beta-galactosidase activity
F126LOC_RS13845	COG1840	ABC-type Fe3 transport system, periplasmic component
F126LOC_RS13850	COG4208	sulfate ABC transporter
F126LOC_RS13855	COG3842	ATPase activity
F126LOC_RS13870	COG3718	enzyme involved in inositol metabolism
F126LOC_RS13880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F126LOC_RS13890	COG1172	Belongs to the binding-protein-dependent transport system permease family
F126LOC_RS13905	COG0673	inositol 2-dehydrogenase activity
F126LOC_RS13910	COG3962	Belongs to the TPP enzyme family
F126LOC_RS13935	COG3706	GGDEF domain
F126LOC_RS13940	COG3711	transcriptional antiterminator
F126LOC_RS13945	COG2723	6-phospho-beta-galactosidase activity
F126LOC_RS13955	COG1605	Chorismate mutase
F126LOC_RS13960	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F126LOC_RS13985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F126LOC_RS13995	COG1215	transferase activity, transferring glycosyl groups
F126LOC_RS14005	COG1051	belongs to the nudix hydrolase family
F126LOC_RS14010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F126LOC_RS14015	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
F126LOC_RS14035	COG0110	maltose O-acetyltransferase activity
F126LOC_RS14045	COG1216	Glycosyl transferase, family 2
F126LOC_RS14045	COG0463	Glycosyl transferase, family 2
F126LOC_RS14050	COG2244	polysaccharide biosynthetic process
F126LOC_RS14060	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F126LOC_RS14070	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F126LOC_RS14090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F126LOC_RS14095	COG1253	flavin adenine dinucleotide binding
F126LOC_RS14100	COG3069	C4-dicarboxylate transmembrane transporter activity
F126LOC_RS14105	COG2982	Protein involved in outer membrane biogenesis
F126LOC_RS14110	COG0717	Belongs to the dCTP deaminase family
F126LOC_RS14115	COG0572	uridine kinase
F126LOC_RS14120	COG0489	protein tyrosine kinase activity
F126LOC_RS14125	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F126LOC_RS14125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F126LOC_RS14130	COG0243	molybdopterin cofactor binding
F126LOC_RS14130	COG3383	formate dehydrogenase (NAD+) activity
F126LOC_RS14135	COG0437	4 iron, 4 sulfur cluster binding
F126LOC_RS14140	COG2864	formate dehydrogenase
F126LOC_RS14145	COG3547	Transposase (IS116 IS110 IS902 family)
F126LOC_RS14160	COG2706	6-phosphogluconolactonase activity
F126LOC_RS14170	COG0561	phosphatase activity
F126LOC_RS14175	COG0837	glucose binding
F126LOC_RS14180	COG2211	Major facilitator Superfamily
F126LOC_RS14190	COG0673	inositol 2-dehydrogenase activity
F126LOC_RS14205	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
F126LOC_RS14210	COG4149	molybdate abc transporter
F126LOC_RS14215	COG0725	ABC transporter, periplasmic molybdate-binding protein
F126LOC_RS14225	COG2005	Transcriptional regulator
F126LOC_RS14225	COG3585	molybdate ion transport
F126LOC_RS14230	COG1119	ATPase activity
F126LOC_RS14235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F126LOC_RS14240	COG2017	converts alpha-aldose to the beta-anomer
F126LOC_RS14260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F126LOC_RS14265	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F126LOC_RS14270	COG0588	phosphoglycerate mutase activity
F126LOC_RS14275	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F126LOC_RS14280	COG1230	cation diffusion facilitator family transporter
F126LOC_RS14290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F126LOC_RS14300	COG1811	Na channel or pump
F126LOC_RS14315	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
F126LOC_RS14320	COG2885	chlorophyll binding
F126LOC_RS14325	COG0823	Involved in the tonB-independent uptake of proteins
F126LOC_RS14330	COG3064	Membrane
F126LOC_RS14335	COG0848	biopolymer transport protein
F126LOC_RS14340	COG0811	peptide transport
F126LOC_RS14345	COG0824	Thioesterase
F126LOC_RS14350	COG3790	cyd operon protein YbgE
F126LOC_RS14355	COG4890	Cyd operon protein YbgT
F126LOC_RS14360	COG1294	oxidase, subunit
F126LOC_RS14365	COG1271	oxidase subunit
F126LOC_RS14375	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F126LOC_RS14380	COG0045	succinate-CoA ligase (ADP-forming) activity
F126LOC_RS14385	COG0508	dehydrogenase complex catalyzes the overall conversion of
F126LOC_RS14390	COG0567	Dehydrogenase, E1 component
F126LOC_RS14395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F126LOC_RS14400	COG1053	succinate dehydrogenase
F126LOC_RS14405	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F126LOC_RS14425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F126LOC_RS14430	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
F126LOC_RS14435	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F126LOC_RS14440	COG1984	allophanate hydrolase subunit 2
F126LOC_RS14445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F126LOC_RS14450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F126LOC_RS14455	COG0415	Belongs to the DNA photolyase family
F126LOC_RS14460	COG3272	Protein of unknown function (DUF1722)
F126LOC_RS14465	COG3842	ATPase activity
F126LOC_RS14470	COG1840	ABC-type Fe3 transport system, periplasmic component
F126LOC_RS14490	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F126LOC_RS14495	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F126LOC_RS14500	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F126LOC_RS14505	COG3547	Transposase (IS116 IS110 IS902 family)
F126LOC_RS14510	COG2205	protein histidine kinase activity
F126LOC_RS14515	COG0745	RESPONSE REGULATOR receiver
F126LOC_RS14525	COG0033	Phosphoglucomutase
F126LOC_RS14530	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
F126LOC_RS14535	COG0596	Alpha beta hydrolase
F126LOC_RS14545	COG0840	transmembrane signaling receptor activity
F126LOC_RS14550	COG0716	FMN binding
F126LOC_RS14555	COG0735	belongs to the Fur family
F126LOC_RS14560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F126LOC_RS14565	COG2190	(PTS) system
F126LOC_RS14565	COG1263	PTS System
F126LOC_RS14565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F126LOC_RS14570	COG0363	glucosamine-6-phosphate deaminase activity
F126LOC_RS14575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F126LOC_RS14580	COG1846	Transcriptional regulator
F126LOC_RS14580	COG1940	carbohydrate kinase activity
F126LOC_RS14585	COG0367	asparagine synthase
F126LOC_RS14630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F126LOC_RS14635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F126LOC_RS14640	COG1702	phosphate starvation-inducible protein PhoH
F126LOC_RS14645	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F126LOC_RS14655	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F126LOC_RS14665	COG0765	amino acid transport
F126LOC_RS14670	COG0765	amino acid transport
F126LOC_RS14675	COG1126	abc transporter atp-binding protein
F126LOC_RS14680	COG3547	Transposase (IS116 IS110 IS902 family)
F126LOC_RS14685	COG2888	peptidyl-tyrosine sulfation
F126LOC_RS14690	COG0495	leucyl-tRNA aminoacylation
F126LOC_RS14695	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
F126LOC_RS14700	COG1466	dna polymerase III delta subunit
F126LOC_RS14705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F126LOC_RS14710	COG0799	negative regulation of ribosome biogenesis
F126LOC_RS14715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
F126LOC_RS14720	COG0768	penicillin binding
F126LOC_RS14725	COG0772	Belongs to the SEDS family
F126LOC_RS14730	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F126LOC_RS14735	COG1686	Belongs to the peptidase S11 family
F126LOC_RS14740	COG2921	Belongs to the UPF0250 family
F126LOC_RS14745	COG0321	lipoyl(octanoyl) transferase activity
F126LOC_RS14750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F126LOC_RS14755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F126LOC_RS14760	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F126LOC_RS14770	COG1794	racemase activity, acting on amino acids and derivatives
F126LOC_RS14780	COG1393	Belongs to the ArsC family
F126LOC_RS14785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F126LOC_RS14790	COG1876	peptidase activity
F126LOC_RS14805	COG0400	carboxylic ester hydrolase activity
F126LOC_RS14810	COG3813	Protein conserved in bacteria
F126LOC_RS14820	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F126LOC_RS14830	COG4178	(ABC) transporter
F126LOC_RS14835	COG4774	siderophore transport
F126LOC_RS14840	COG1595	DNA-templated transcription, initiation
F126LOC_RS14845	COG3712	iron ion homeostasis
F126LOC_RS14850	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
F126LOC_RS14865	COG0312	modulator of DNA gyrase
F126LOC_RS14870	COG0312	modulator of DNA gyrase
F126LOC_RS14875	COG3118	belongs to the thioredoxin family
F126LOC_RS14880	COG1444	tRNA N-acetyltransferase activity
F126LOC_RS14885	COG2707	UPF0756 membrane protein
F126LOC_RS14890	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F126LOC_RS14895	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
F126LOC_RS14905	COG2716	regulation of RNA biosynthetic process
F126LOC_RS14910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F126LOC_RS14915	COG4783	chaperone-mediated protein folding
F126LOC_RS14920	COG1393	Belongs to the ArsC family
F126LOC_RS14925	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F126LOC_RS14930	COG2233	PERMEase
F126LOC_RS14935	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F126LOC_RS14940	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F126LOC_RS14945	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F126LOC_RS14950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F126LOC_RS14960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F126LOC_RS14965	COG3547	Transposase (IS116 IS110 IS902 family)
F126LOC_RS14970	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F126LOC_RS14975	COG4181	ATPase activity
F126LOC_RS14980	COG2755	lipolytic protein G-D-S-L family
F126LOC_RS14985	COG0300	oxidoreductase activity
F126LOC_RS14990	COG3118	belongs to the thioredoxin family
F126LOC_RS15000	COG0814	amino acid
F126LOC_RS15010	COG0753	catalase activity
F126LOC_RS15020	COG1441	menaquinone biosynthetic process
F126LOC_RS15025	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F126LOC_RS15030	COG0596	Alpha beta hydrolase
F126LOC_RS15035	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
F126LOC_RS15040	COG1169	isochorismate synthase
F126LOC_RS15045	COG2223	nitrite transmembrane transporter activity
F126LOC_RS15050	COG2198	Histidine kinase
F126LOC_RS15050	COG0642	Histidine kinase
F126LOC_RS15055	COG2197	response regulator
F126LOC_RS15060	COG0784	Response regulator, receiver
F126LOC_RS15060	COG2205	protein histidine kinase activity
F126LOC_RS15070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F126LOC_RS15075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F126LOC_RS15080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F126LOC_RS15085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F126LOC_RS15090	COG0330	HflC and HflK could
F126LOC_RS15095	COG1585	Membrane protein implicated in regulation of membrane protease activity
F126LOC_RS15105	COG2217	Heavy metal translocating P-type atpase
F126LOC_RS15120	COG3735	TraB family
F126LOC_RS15130	COG5434	Belongs to the glycosyl hydrolase 28 family
F126LOC_RS15135	COG0523	cobalamin synthesis protein
F126LOC_RS15140	COG2879	small protein
F126LOC_RS15145	COG1966	Carbon starvation protein
F126LOC_RS15170	COG0737	Belongs to the 5'-nucleotidase family
F126LOC_RS15175	COG4651	solute:proton antiporter activity
F126LOC_RS15175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F126LOC_RS15180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F126LOC_RS15185	COG0563	adenylate kinase activity
F126LOC_RS15190	COG0326	Molecular chaperone. Has ATPase activity
F126LOC_RS15195	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F126LOC_RS15200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
F126LOC_RS15210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F126LOC_RS15215	COG2832	Protein of unknown function (DUF454)
F126LOC_RS15230	COG1309	transcriptional regulator
F126LOC_RS15235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F126LOC_RS15240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F126LOC_RS15245	COG0254	rRNA binding
F126LOC_RS15250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F126LOC_RS15270	COG3695	enzyme binding
F126LOC_RS15275	COG3126	Type III secretion system lipoprotein chaperone (YscW)
F126LOC_RS15280	COG1946	Acyl-CoA thioesterase
F126LOC_RS15285	COG0004	ammonium transporteR
F126LOC_RS15290	COG0347	Belongs to the P(II) protein family
F126LOC_RS15295	COG1132	(ABC) transporter
F126LOC_RS15300	COG1132	(ABC) transporter
F126LOC_RS15305	COG1522	sequence-specific DNA binding
F126LOC_RS15315	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F126LOC_RS15320	COG0824	Thioesterase
F126LOC_RS15325	COG1555	photosystem II stabilization
F126LOC_RS15330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F126LOC_RS15335	COG0776	regulation of translation
F126LOC_RS15340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F126LOC_RS15345	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F126LOC_RS15350	COG0740	serine-type endopeptidase activity
F126LOC_RS15355	COG0544	peptidyl-prolyl cis-trans isomerase activity
F126LOC_RS15360	COG0271	Belongs to the BolA IbaG family
F126LOC_RS15365	COG3056	Lipoprotein
F126LOC_RS15370	COG2223	nitrite transmembrane transporter activity
F126LOC_RS15375	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F126LOC_RS15380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F126LOC_RS15385	COG1845	cytochrome c oxidase, subunit III
F126LOC_RS15390	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F126LOC_RS15395	COG0109	protoheme IX farnesyltransferase activity
F126LOC_RS15400	COG2814	Major facilitator Superfamily
F126LOC_RS15405	COG1666	GTP binding
F126LOC_RS15410	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F126LOC_RS15420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F126LOC_RS15420	COG0301	tRNA thio-modification
F126LOC_RS15425	COG1722	exodeoxyribonuclease VII activity
F126LOC_RS15430	COG0142	geranyltranstransferase activity
F126LOC_RS15435	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F126LOC_RS15440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F126LOC_RS15445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F126LOC_RS15450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F126LOC_RS15455	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F126LOC_RS15460	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F126LOC_RS15460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F126LOC_RS15465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F126LOC_RS15470	COG4238	major outer membrane lipoprotein
F126LOC_RS15475	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F126LOC_RS15480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F126LOC_RS15485	COG1862	Preprotein translocase
F126LOC_RS15490	COG0343	queuine tRNA-ribosyltransferase activity
F126LOC_RS15495	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F126LOC_RS15500	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
F126LOC_RS15505	COG0450	alkyl hydroperoxide reductase
F126LOC_RS15510	COG0668	transmembrane transport
F126LOC_RS15515	COG3547	Transposase (IS116 IS110 IS902 family)
F126LOC_RS15525	COG1114	Component of the transport system for branched-chain amino acids
F126LOC_RS15530	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F126LOC_RS15550	COG0420	3'-5' exonuclease activity
F126LOC_RS15555	COG0419	ATPase involved in DNA repair
F126LOC_RS15560	COG1940	carbohydrate kinase activity
F126LOC_RS15565	COG2974	May be involved in recombination
F126LOC_RS15575	COG2188	Transcriptional regulator
F126LOC_RS15580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F126LOC_RS15585	COG1397	ADP-ribosylglycohydrolase
F126LOC_RS15595	COG3123	guanosine phosphorylase activity
F126LOC_RS15600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F126LOC_RS15610	COG4615	Cyclic peptide transporter
F126LOC_RS15640	COG5297	Belongs to the glycosyl hydrolase family 6
F126LOC_RS15645	COG1312	Catalyzes the dehydration of D-mannonate
F126LOC_RS15650	COG2186	Transcriptional regulator
F126LOC_RS15680	COG0583	DNA-binding transcription factor activity
F126LOC_RS15690	COG2951	lytic endotransglycosylase activity
F126LOC_RS15695	COG2824	Alkylphosphonate utilization operon protein PhnA
F126LOC_RS15700	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F126LOC_RS15705	COG1595	DNA-templated transcription, initiation
F126LOC_RS15710	COG3712	iron ion homeostasis
F126LOC_RS15715	COG4772	TonB-dependent receptor
F126LOC_RS15720	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
F126LOC_RS15725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F126LOC_RS15730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F126LOC_RS15735	COG1120	ATPase activity
F126LOC_RS15760	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
F126LOC_RS15765	COG3015	lipoprotein NlpE involved in copper resistance
F126LOC_RS15780	COG4568	rho-dependent transcription termination
F126LOC_RS15785	COG0037	tRNA processing
F126LOC_RS15790	COG0346	lactoylglutathione lyase activity
F126LOC_RS15795	COG0825	malonyl-CoA metabolic process
F126LOC_RS15800	COG0587	DNA-directed DNA polymerase activity
F126LOC_RS15805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F126LOC_RS15810	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F126LOC_RS15815	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F126LOC_RS15820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F126LOC_RS15825	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F126LOC_RS15830	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
F126LOC_RS15835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F126LOC_RS15840	COG0750	zinc metalloprotease
F126LOC_RS15845	COG0575	Belongs to the CDS family
F126LOC_RS15850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F126LOC_RS15855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F126LOC_RS15860	COG0233	cytoplasmic translational termination
F126LOC_RS15865	COG0528	UMP kinase activity
F126LOC_RS15870	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
F126LOC_RS15875	COG0052	Belongs to the universal ribosomal protein uS2 family
F126LOC_RS15885	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F126LOC_RS15930	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F126LOC_RS15930	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F126LOC_RS15935	COG1611	Belongs to the LOG family
F126LOC_RS15940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F126LOC_RS15945	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
F126LOC_RS15950	COG2363	Small membrane protein
F126LOC_RS15955	COG0583	DNA-binding transcription factor activity
F126LOC_RS15965	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F126LOC_RS15970	COG2166	iron-sulfur cluster assembly
F126LOC_RS15975	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F126LOC_RS15985	COG0747	negative chemotaxis
F126LOC_RS15995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F126LOC_RS16000	COG4172	Belongs to the ABC transporter superfamily
F126LOC_RS16005	COG1473	amidohydrolase
F126LOC_RS16015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F126LOC_RS16020	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F126LOC_RS16040	COG0860	N-Acetylmuramoyl-L-alanine amidase
F126LOC_RS16045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F126LOC_RS16045	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F126LOC_RS16055	COG1609	Transcriptional regulator
F126LOC_RS16060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F126LOC_RS16065	COG1074	ATP-dependent DNA helicase activity
F126LOC_RS16070	COG1025	Belongs to the peptidase M16 family
F126LOC_RS16075	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F126LOC_RS16090	COG4795	General secretion pathway protein
F126LOC_RS16095	COG4969	Belongs to the N-Me-Phe pilin family
F126LOC_RS16100	COG1569	PIN domain
F126LOC_RS16105	COG3311	Transcriptional regulator
F126LOC_RS16110	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
F126LOC_RS16115	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
F126LOC_RS16125	COG0494	nUDIX hydrolase
F126LOC_RS16130	COG3066	DNA modification
F126LOC_RS16135	COG0861	Integral membrane protein TerC family
F126LOC_RS16145	COG0667	Aldo Keto reductase
F126LOC_RS16150	COG3639	organic phosphonate transmembrane transporter activity
F126LOC_RS16160	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
F126LOC_RS16170	COG3454	Phosphonate metabolism
F126LOC_RS16175	COG4778	phosphonate C-P lyase system protein PhnL
F126LOC_RS16180	COG4107	phosphonate C-P lyase system protein PhnK
F126LOC_RS16185	COG3627	carbon phosphorus lyase activity
F126LOC_RS16190	COG3626	phosphonate metabolism
F126LOC_RS16195	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F126LOC_RS16200	COG3624	Phosphonate C-P lyase system protein PhnG
F126LOC_RS16205	COG2188	Transcriptional regulator
F126LOC_RS16210	COG1404	Belongs to the peptidase S8 family
F126LOC_RS16220	COG3171	Protein conserved in bacteria
F126LOC_RS16225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F126LOC_RS16235	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
F126LOC_RS16240	COG0741	lytic transglycosylase activity
F126LOC_RS16245	COG2169	Transcriptional regulator
F126LOC_RS16245	COG1917	Cupin 2, conserved barrel domain protein
F126LOC_RS16255	COG5564	TIM-barrel signal transduction protein
F126LOC_RS16260	COG5441	Belongs to the UPF0261 family
F126LOC_RS16280	COG1982	Orn Lys Arg decarboxylase major
F126LOC_RS16315	COG0583	DNA-binding transcription factor activity
F126LOC_RS16365	COG0604	alcohol dehydrogenase
F126LOC_RS16405	COG2003	Belongs to the UPF0758 family
F126LOC_RS16660	COG0741	lytic transglycosylase activity
F126LOC_RS16670	COG1459	type II secretion system
F126LOC_RS16675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F126LOC_RS16715	COG0629	single-stranded DNA binding
F126LOC_RS16725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F126LOC_RS16785	COG3547	Transposase (IS116 IS110 IS902 family)
F126LOC_RS16795	COG1045	serine acetyltransferase
F126LOC_RS16810	COG0438	transferase activity, transferring glycosyl groups
F126LOC_RS16815	COG0297	glycogen (starch) synthase activity
F126LOC_RS16860	COG2207	Transcriptional regulator
F126LOC_RS16865	COG2814	Major facilitator Superfamily
F126LOC_RS16870	COG1846	Transcriptional regulator
F126LOC_RS16915	COG2249	NAD(P)H dehydrogenase (quinone) activity
F126LOC_RS16980	COG3121	Chaperone
F126LOC_RS17005	COG4948	Mandelate Racemase Muconate Lactonizing
F126LOC_RS17010	COG4773	Receptor
F126LOC_RS17020	COG0583	DNA-binding transcription factor activity
F126LOC_RS17045	COG2814	Major facilitator Superfamily
F126LOC_RS17065	COG0811	peptide transport
F126LOC_RS17080	COG1802	Transcriptional regulator
F126LOC_RS17085	COG0246	Mannitol dehydrogenase
F126LOC_RS17090	COG0477	Major facilitator Superfamily
F126LOC_RS17095	COG1063	alcohol dehydrogenase
F126LOC_RS17100	COG4948	Mandelate Racemase Muconate Lactonizing
F126LOC_RS17115	COG0583	DNA-binding transcription factor activity
F126LOC_RS17125	COG0437	4 iron, 4 sulfur cluster binding
F126LOC_RS17130	COG3301	Polysulphide reductase, NrfD
F126LOC_RS17135	COG0477	Major facilitator Superfamily
F126LOC_RS17140	COG0431	NADPH-dependent FMN reductase
F126LOC_RS17140	COG3976	FMN-binding domain protein
F126LOC_RS17140	COG1053	succinate dehydrogenase
F126LOC_RS17155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F126LOC_RS17155	COG2169	Transcriptional regulator
F126LOC_RS17180	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F126LOC_RS17180	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F126LOC_RS17185	COG3604	Transcriptional regulator
F126LOC_RS17190	COG0426	domain, Protein
F126LOC_RS17190	COG1773	rubredoxin
F126LOC_RS17195	COG0446	pyridine nucleotide-disulphide oxidoreductase
F126LOC_RS17205	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F126LOC_RS17215	COG0531	amino acid
F126LOC_RS17220	COG3115	cell septum assembly
F126LOC_RS17225	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
F126LOC_RS17235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F126LOC_RS17245	COG2190	(PTS) system
F126LOC_RS17250	COG2205	protein histidine kinase activity
F126LOC_RS17255	COG0745	RESPONSE REGULATOR receiver
F126LOC_RS17260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F126LOC_RS17265	COG1136	(ABC) transporter
F126LOC_RS17265	COG0577	efflux transmembrane transporter activity
F126LOC_RS17270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F126LOC_RS17275	COG4208	sulfate ABC transporter
F126LOC_RS17280	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F126LOC_RS17285	COG4150	thiosulfate binding
F126LOC_RS17290	COG2837	iron assimilation
F126LOC_RS17300	COG4178	(ABC) transporter
F126LOC_RS17305	COG0612	Peptidase, M16
F126LOC_RS17310	COG4771	TonB-dependent receptor
F126LOC_RS17320	COG0456	acetyltransferase
F126LOC_RS17325	COG0408	coproporphyrinogen oxidase activity
F126LOC_RS17330	COG1671	Belongs to the UPF0178 family
F126LOC_RS17335	COG0814	amino acid
F126LOC_RS17350	COG2084	Dehydrogenase
F126LOC_RS17355	COG1082	Xylose isomerase domain protein TIM barrel
F126LOC_RS17360	COG0149	triose-phosphate isomerase activity
F126LOC_RS17365	COG2376	Dihydroxyacetone kinase
F126LOC_RS17375	COG0698	ribose 5-phosphate isomerase
F126LOC_RS17380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F126LOC_RS17385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F126LOC_RS17390	COG1263	PTS System
F126LOC_RS17390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F126LOC_RS17390	COG2190	(PTS) system
F126LOC_RS17395	COG2723	6-phospho-beta-galactosidase activity
F126LOC_RS17400	COG3711	transcriptional antiterminator
F126LOC_RS17405	COG1609	Transcriptional regulator
F126LOC_RS17435	COG0494	nUDIX hydrolase
F126LOC_RS17445	COG0477	Major facilitator Superfamily
F126LOC_RS17450	COG1942	4-Oxalocrotonate Tautomerase
F126LOC_RS17455	COG1914	H( )-stimulated, divalent metal cation uptake system
F126LOC_RS17460	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F126LOC_RS17465	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F126LOC_RS17470	COG0497	DNA recombination
F126LOC_RS17480	COG2914	Belongs to the UPF0125 (RnfH) family
F126LOC_RS17485	COG2867	negative regulation of translational initiation
F126LOC_RS17490	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
F126LOC_RS17610	COG3566	protein conserved in bacteria
F126LOC_RS17620	COG3567	Phage-associated protein, HI1409 family
F126LOC_RS17625	COG5410	chromosome segregation
F126LOC_RS17760	COG3756	Protein conserved in bacteria
F126LOC_RS17800	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F126LOC_RS17810	COG0582	viral genome integration into host DNA
F126LOC_RS17840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F126LOC_RS17845	COG1280	lysine exporter protein (LysE YggA)
F126LOC_RS17865	COG0674	pyruvate-flavodoxin oxidoreductase activity
F126LOC_RS17865	COG1013	pyruvate-flavodoxin oxidoreductase activity
F126LOC_RS17865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F126LOC_RS17865	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
F126LOC_RS17870	COG3038	cytochrome b561
F126LOC_RS17875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F126LOC_RS17880	COG1376	ErfK ybiS ycfS ynhG family protein
F126LOC_RS17885	COG2873	o-acetylhomoserine
F126LOC_RS17890	COG0246	Mannitol dehydrogenase
F126LOC_RS17910	COG3712	iron ion homeostasis
F126LOC_RS17920	COG4774	siderophore transport
F126LOC_RS17930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F126LOC_RS17935	COG3162	membrane
F126LOC_RS17940	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F126LOC_RS17945	COG5464	transposase or invertase
F126LOC_RS18025	COG4964	Belongs to the GSP D family
F126LOC_RS18045	COG2205	protein histidine kinase activity
F126LOC_RS18055	COG0025	NhaP-type Na H and K H
F126LOC_RS18060	COG2252	PERMEase
F126LOC_RS18085	COG1953	Uracil, thiamine, allantoin
F126LOC_RS18090	COG1560	Kdo2-lipid A biosynthetic process
F126LOC_RS18100	COG4319	ketosteroid isomerase
F126LOC_RS18135	COG4974	Belongs to the 'phage' integrase family
F126LOC_RS18155	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F126LOC_RS18165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F126LOC_RS18170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F126LOC_RS18175	COG4974	Belongs to the 'phage' integrase family
F126LOC_RS18180	COG0477	Major facilitator Superfamily
F126LOC_RS18190	COG0716	FMN binding
F126LOC_RS18200	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
F126LOC_RS18210	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F126LOC_RS18215	COG0354	folic acid binding
F126LOC_RS18220	COG1272	protein, Hemolysin III
F126LOC_RS18240	COG2211	Major facilitator Superfamily
F126LOC_RS18245	COG1653	transport
F126LOC_RS18250	COG3842	ATPase activity
F126LOC_RS18255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F126LOC_RS18265	COG1175	transmembrane transport
F126LOC_RS18275	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F126LOC_RS18275	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F126LOC_RS18280	COG0509	glycine decarboxylation via glycine cleavage system
F126LOC_RS18285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F126LOC_RS18290	COG1454	alcohol dehydrogenase
F126LOC_RS18340	COG0656	L-ascorbic acid biosynthetic process
F126LOC_RS18345	COG2813	Specifically methylates the guanine in position
F126LOC_RS18350	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
F126LOC_RS18355	COG0456	acetyltransferase
F126LOC_RS18375	COG0583	DNA-binding transcription factor activity
F126LOC_RS18380	COG1595	DNA-templated transcription, initiation
F126LOC_RS18385	COG3712	iron ion homeostasis
F126LOC_RS18395	COG4178	(ABC) transporter
F126LOC_RS18415	COG0813	purine-nucleoside phosphorylase activity
F126LOC_RS18420	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
F126LOC_RS18425	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
F126LOC_RS18430	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
F126LOC_RS18435	COG1473	amidohydrolase
F126LOC_RS18440	COG2827	Endonuclease containing a URI domain
F126LOC_RS18445	COG3153	acetyltransferase
F126LOC_RS18450	COG3154	lipid carrier protein
F126LOC_RS18455	COG0826	peptidase U32
F126LOC_RS18460	COG0826	peptidase U32
F126LOC_RS18465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F126LOC_RS18470	COG0513	Belongs to the DEAD box helicase family
F126LOC_RS18485	COG1185	polyribonucleotide nucleotidyltransferase activity
F126LOC_RS18490	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F126LOC_RS18495	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F126LOC_RS18500	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F126LOC_RS18505	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F126LOC_RS18515	COG0779	Required for maturation of 30S ribosomal subunits
F126LOC_RS18565	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F126LOC_RS18570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F126LOC_RS18575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F126LOC_RS18580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F126LOC_RS18585	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
F126LOC_RS18590	COG1534	Rna-binding protein
F126LOC_RS18600	COG2027	D-alanyl-D-alanine carboxypeptidase
F126LOC_RS18605	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F126LOC_RS18610	COG0697	spore germination
F126LOC_RS18615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F126LOC_RS18620	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F126LOC_RS18625	COG0142	geranyltranstransferase activity
F126LOC_RS18640	COG3423	Transcriptional regulator
F126LOC_RS18645	COG0039	L-malate dehydrogenase activity
F126LOC_RS18650	COG1438	arginine binding
F126LOC_RS18655	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F126LOC_RS18660	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F126LOC_RS18665	COG0358	DNA primase activity
F126LOC_RS18675	COG3663	DNA glycosylase
F126LOC_RS18790	COG4695	Portal protein
F126LOC_RS18810	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F126LOC_RS18860	COG4974	Belongs to the 'phage' integrase family
F126LOC_RS18865	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F126LOC_RS18865	COG2755	lipolytic protein G-D-S-L family
F126LOC_RS18870	COG0583	DNA-binding transcription factor activity
F126LOC_RS18880	COG0243	molybdopterin cofactor binding
F126LOC_RS18905	COG2199	diguanylate cyclase activity
F126LOC_RS18910	COG3678	ATP-independent chaperone mediated protein folding
F126LOC_RS18920	COG1902	pentaerythritol trinitrate reductase activity
F126LOC_RS18920	COG0446	pyridine nucleotide-disulphide oxidoreductase
F126LOC_RS18925	COG2813	Specifically methylates the guanine in position
F126LOC_RS18930	COG0673	inositol 2-dehydrogenase activity
F126LOC_RS18935	COG0861	Integral membrane protein TerC family
F126LOC_RS18940	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
F126LOC_RS18950	COG2721	sulfolactate sulfo-lyase activity
F126LOC_RS18955	COG0246	Mannitol dehydrogenase
F126LOC_RS18960	COG1904	glucuronate isomerase
F126LOC_RS18965	COG2271	Major facilitator Superfamily
F126LOC_RS18975	COG0586	Pfam SNARE associated Golgi protein
F126LOC_RS18985	COG1422	Protein of unknown function (DUF1090)
F126LOC_RS18990	COG4575	ribosome binding
F126LOC_RS18995	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
F126LOC_RS19005	COG2259	Doxx family
F126LOC_RS19010	COG0435	Glutathione S-transferase
F126LOC_RS19015	COG0583	DNA-binding transcription factor activity
F126LOC_RS19020	COG1741	Belongs to the pirin family
F126LOC_RS19025	COG0735	belongs to the Fur family
F126LOC_RS19030	COG3237	CsbD-like
F126LOC_RS19035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F126LOC_RS19040	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F126LOC_RS19045	COG2937	Belongs to the GPAT DAPAT family
F126LOC_RS19050	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F126LOC_RS19055	COG3161	chorismate lyase activity
F126LOC_RS19060	COG0459	protein refolding
F126LOC_RS19065	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F126LOC_RS19080	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F126LOC_RS19085	COG1324	tolerance protein
F126LOC_RS19090	COG4232	protein-disulfide reductase activity
F126LOC_RS19095	COG1309	transcriptional regulator
F126LOC_RS19115	COG0582	viral genome integration into host DNA
F126LOC_RS19170	COG3423	Transcriptional regulator
F126LOC_RS19190	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F126LOC_RS19195	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F126LOC_RS19200	COG3454	Phosphonate metabolism
F126LOC_RS19205	COG4778	phosphonate C-P lyase system protein PhnL
F126LOC_RS19210	COG4107	phosphonate C-P lyase system protein PhnK
F126LOC_RS19215	COG3627	carbon phosphorus lyase activity
F126LOC_RS19220	COG3626	phosphonate metabolism
F126LOC_RS19225	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F126LOC_RS19230	COG3624	Phosphonate C-P lyase system protein PhnG
F126LOC_RS19240	COG0028	Belongs to the TPP enzyme family
F126LOC_RS19240	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
F126LOC_RS19255	COG0318	PFAM AMP-dependent synthetase and ligase
F126LOC_RS19255	COG0300	oxidoreductase activity
F126LOC_RS19255	COG1028	Short-chain dehydrogenase reductase Sdr
F126LOC_RS19255	COG3321	synthase
F126LOC_RS19255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F126LOC_RS19265	COG1028	Short-chain dehydrogenase reductase Sdr
F126LOC_RS19270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F126LOC_RS19275	COG3433	isochorismatase activity
F126LOC_RS19275	COG1535	isochorismatase
F126LOC_RS19280	COG1021	2,3-dihydroxybenzoate-AMP ligase
F126LOC_RS19285	COG1169	isochorismate synthase
F126LOC_RS19295	COG4771	TonB-dependent receptor
F126LOC_RS19305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F126LOC_RS19310	COG0084	hydrolase, TatD family'
F126LOC_RS19320	COG5487	UPF0391 membrane protein
F126LOC_RS19325	COG2823	Periplasmic or secreted lipoprotein
F126LOC_RS19330	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F126LOC_RS19340	COG3726	membrane protein affecting hemolysin expression
F126LOC_RS19345	COG0560	Phosphoserine phosphatase
F126LOC_RS19360	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F126LOC_RS19370	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
F126LOC_RS19375	COG3079	Belongs to the UPF0149 family
F126LOC_RS19380	COG0006	proline dipeptidase activity
F126LOC_RS19385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F126LOC_RS19390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F126LOC_RS19395	COG3157	Type VI secretion system effector, Hcp
F126LOC_RS19425	COG2130	NADP-dependent
F126LOC_RS19430	COG2862	Uncharacterized protein family, UPF0114
F126LOC_RS19450	COG3477	response to acidic pH
F126LOC_RS19455	COG0747	negative chemotaxis
F126LOC_RS19460	COG0601	transmembrane transport
F126LOC_RS19465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F126LOC_RS19485	COG1917	Cupin 2, conserved barrel domain protein
F126LOC_RS19485	COG4977	sequence-specific DNA binding
F126LOC_RS19490	COG1917	Cupin 2, conserved barrel domain protein
F126LOC_RS19490	COG2169	Transcriptional regulator
F126LOC_RS19495	COG1070	Carbohydrate kinase
F126LOC_RS19500	COG4806	L-rhamnose isomerase
F126LOC_RS19505	COG0235	Class ii aldolase
F126LOC_RS19510	COG3254	rhamnose metabolic process
F126LOC_RS19515	COG0840	transmembrane signaling receptor activity
F126LOC_RS19525	COG0840	transmembrane signaling receptor activity
F126LOC_RS19530	COG0288	reversible hydration of carbon dioxide
F126LOC_RS19535	COG0659	secondary active sulfate transmembrane transporter activity
F126LOC_RS19565	COG3541	Predicted nucleotidyltransferase
F126LOC_RS19570	COG1690	Belongs to the RtcB family
F126LOC_RS19575	COG4650	regulator
F126LOC_RS19595	COG0583	DNA-binding transcription factor activity
F126LOC_RS19610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F126LOC_RS19630	COG2850	peptidyl-arginine hydroxylation
F126LOC_RS19635	COG2304	oxidoreductase activity
F126LOC_RS19665	COG1136	(ABC) transporter
F126LOC_RS19675	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F126LOC_RS19690	COG2046	Belongs to the sulfate adenylyltransferase family
F126LOC_RS19690	COG0529	Catalyzes the synthesis of activated sulfate
F126LOC_RS19720	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
F126LOC_RS19735	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
F126LOC_RS19765	COG0795	lipopolysaccharide-transporting ATPase activity
F126LOC_RS19770	COG0795	lipopolysaccharide-transporting ATPase activity
F126LOC_RS19775	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F126LOC_RS19780	COG2927	DNA polymerase III (CHI subunit)
F126LOC_RS19785	COG0525	valine-tRNA ligase activity
F126LOC_RS19790	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
F126LOC_RS19795	COG0840	transmembrane signaling receptor activity
F126LOC_RS19800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F126LOC_RS19805	COG0501	Belongs to the peptidase M48B family
F126LOC_RS19825	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F126LOC_RS19830	COG2731	YhcH YjgK YiaL family protein
F126LOC_RS19835	COG0540	Belongs to the ATCase OTCase family
F126LOC_RS19840	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
F126LOC_RS19860	COG0702	epimerase
F126LOC_RS19865	COG3787	Belongs to the UPF0306 family
F126LOC_RS19875	COG2814	Major facilitator Superfamily
F126LOC_RS19880	COG0076	glutamate decarboxylase activity
F126LOC_RS19930	COG0848	biopolymer transport protein
F126LOC_RS19940	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F126LOC_RS19955	COG0626	cystathionine gamma-synthase activity
F126LOC_RS19960	COG0586	Pfam SNARE associated Golgi protein
F126LOC_RS19965	COG2207	Transcriptional regulator
F126LOC_RS19970	COG0778	Nitroreductase
F126LOC_RS19975	COG1979	alcohol dehydrogenase
F126LOC_RS19980	COG0656	L-ascorbic acid biosynthetic process
F126LOC_RS19990	COG2132	Multicopper oxidase
F126LOC_RS19995	COG0204	Acyl-transferase
F126LOC_RS20000	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F126LOC_RS20020	COG1629	transport
F126LOC_RS20020	COG4771	TonB-dependent receptor
F126LOC_RS20025	COG3711	transcriptional antiterminator
F126LOC_RS20030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F126LOC_RS20030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F126LOC_RS20030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F126LOC_RS20035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F126LOC_RS20040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F126LOC_RS20040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F126LOC_RS20055	COG2249	NAD(P)H dehydrogenase (quinone) activity
F126LOC_RS20060	COG0583	DNA-binding transcription factor activity
F126LOC_RS20075	COG0187	DNA topoisomerase II activity
F126LOC_RS20080	COG3150	esterase
F126LOC_RS20085	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F126LOC_RS20090	COG3151	Protein conserved in bacteria
F126LOC_RS20095	COG0494	nUDIX hydrolase
F126LOC_RS20105	COG5463	Belongs to the UPF0441 family
F126LOC_RS20110	COG0754	glutathionylspermidine amidase activity
F126LOC_RS20115	COG3384	dioxygenase
F126LOC_RS20135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F126LOC_RS20140	COG3107	peptidoglycan biosynthetic process
F126LOC_RS20145	COG0792	nuclease activity
F126LOC_RS20150	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
F126LOC_RS20155	COG2823	Periplasmic or secreted lipoprotein
F126LOC_RS20165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F126LOC_RS20170	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
F126LOC_RS20175	COG0784	Response regulator, receiver
F126LOC_RS20175	COG5002	protein histidine kinase activity
F126LOC_RS20175	COG2198	Histidine kinase
F126LOC_RS20180	COG1242	4 iron, 4 sulfur cluster binding
F126LOC_RS20185	COG0067	glutamate synthase
F126LOC_RS20185	COG0069	glutamate synthase activity
F126LOC_RS20185	COG0070	glutamate synthase
F126LOC_RS20190	COG0493	'glutamate synthase
F126LOC_RS20205	COG2969	positive regulation of protein catabolic process
F126LOC_RS20210	COG0625	glutathione transferase activity
F126LOC_RS20215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F126LOC_RS20220	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F126LOC_RS20225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F126LOC_RS20230	COG3105	Protein conserved in bacteria
F126LOC_RS20235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F126LOC_RS20240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F126LOC_RS20245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F126LOC_RS20250	COG5007	Belongs to the BolA IbaG family
F126LOC_RS20255	COG3113	response to antibiotic
F126LOC_RS20260	COG2854	intermembrane phospholipid transfer
F126LOC_RS20265	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F126LOC_RS20270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F126LOC_RS20275	COG1127	ABC transporter
F126LOC_RS20280	COG0530	calcium, potassium:sodium antiporter activity
F126LOC_RS20285	COG0517	IMP dehydrogenase activity
F126LOC_RS20285	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F126LOC_RS20290	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F126LOC_RS20295	COG3117	lipopolysaccharide transmembrane transporter activity
F126LOC_RS20300	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F126LOC_RS20305	COG1137	ATPase activity
F126LOC_RS20310	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F126LOC_RS20315	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F126LOC_RS20320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F126LOC_RS20325	COG1660	Displays ATPase and GTPase activities
F126LOC_RS20330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F126LOC_RS20335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F126LOC_RS20340	COG0312	modulator of DNA gyrase
F126LOC_RS20345	COG3028	Belongs to the UPF0307 family
F126LOC_RS20355	COG1289	transmembrane transporter activity
F126LOC_RS20360	COG1566	PFAM secretion protein HlyD family protein
F126LOC_RS20370	COG0583	DNA-binding transcription factor activity
F126LOC_RS20385	COG0312	modulator of DNA gyrase
F126LOC_RS20390	COG3164	Protein of unknown function
F126LOC_RS20395	COG1530	ribonuclease E activity
F126LOC_RS20400	COG0424	maF-like protein
F126LOC_RS20405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F126LOC_RS20410	COG1792	Involved in formation and maintenance of cell shape
F126LOC_RS20415	COG1077	Cell shape determining protein MreB Mrl
F126LOC_RS20425	COG2200	EAL domain
F126LOC_RS20425	COG2199	diguanylate cyclase activity
F126LOC_RS20430	COG0604	alcohol dehydrogenase
F126LOC_RS20435	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F126LOC_RS20440	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
F126LOC_RS20445	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F126LOC_RS20450	COG0511	ligase activity, forming carbon-carbon bonds
F126LOC_RS20455	COG0439	Biotin carboxylase
F126LOC_RS20460	COG2207	Transcriptional regulator
F126LOC_RS20465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F126LOC_RS20475	COG3924	membrane
F126LOC_RS20480	COG4145	pantothenate transmembrane transporter activity
F126LOC_RS20485	COG2264	protein methyltransferase activity
F126LOC_RS20500	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F126LOC_RS20520	COG3935	DnaD domain protein
F126LOC_RS20540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F126LOC_RS20545	COG0765	amino acid transport
F126LOC_RS20550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F126LOC_RS20555	COG4597	amino acid ABC transporter
F126LOC_RS20560	COG0765	amino acid transport
F126LOC_RS20565	COG1126	abc transporter atp-binding protein
F126LOC_RS20595	COG0138	bifunctional purine biosynthesis protein purh
F126LOC_RS20600	COG0151	Belongs to the GarS family
F126LOC_RS20620	COG1515	deoxyribonuclease V activity
F126LOC_RS20625	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
F126LOC_RS20630	COG2816	NAD+ diphosphatase activity
F126LOC_RS20635	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
F126LOC_RS20640	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
F126LOC_RS20645	COG0352	thiamine-phosphate diphosphorylase activity
F126LOC_RS20650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F126LOC_RS20655	COG2104	thiamine diphosphate biosynthetic process
F126LOC_RS20660	COG2022	thiamine diphosphate biosynthetic process
F126LOC_RS20670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F126LOC_RS20675	COG5457	Domain of unknown function (DUF1127)
F126LOC_RS20680	COG0477	Major facilitator Superfamily
F126LOC_RS20685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F126LOC_RS20690	COG0085	RNA polymerase activity
F126LOC_RS20695	COG0222	ribosome binding
F126LOC_RS20700	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F126LOC_RS20705	COG0081	regulation of translation
F126LOC_RS20710	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F126LOC_RS20715	COG0250	Participates in transcription elongation, termination and antitermination
F126LOC_RS20755	COG1072	(Pantothenic acid kinase))
F126LOC_RS20760	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
F126LOC_RS20760	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
F126LOC_RS20765	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F126LOC_RS20800	COG1739	Uncharacterized protein family UPF0029
F126LOC_RS20805	COG0006	proline dipeptidase activity
F126LOC_RS20810	COG1024	Enoyl-CoA hydratase
F126LOC_RS20810	COG1250	3-hydroxyacyl-CoA dehydrogenase
F126LOC_RS20815	COG0183	Belongs to the thiolase family
F126LOC_RS20825	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F126LOC_RS20830	COG0250	Participates in transcription elongation, termination and antitermination
F126LOC_RS20840	COG0084	hydrolase, TatD family'
F126LOC_RS20845	COG0805	protein transport
F126LOC_RS20850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F126LOC_RS20855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F126LOC_RS20860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F126LOC_RS20870	COG2226	methyltransferase
F126LOC_RS20875	COG1322	Protein conserved in bacteria
F126LOC_RS20880	COG0165	Argininosuccinate lyase
F126LOC_RS20885	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F126LOC_RS20890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F126LOC_RS20895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F126LOC_RS20900	COG2188	Transcriptional regulator
F126LOC_RS20905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F126LOC_RS20910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F126LOC_RS20935	COG4948	Mandelate Racemase Muconate Lactonizing
F126LOC_RS20940	COG2190	(PTS) system
F126LOC_RS20940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F126LOC_RS20940	COG1263	PTS System
F126LOC_RS20945	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
F126LOC_RS20960	COG0412	Dienelactone hydrolase
F126LOC_RS20965	COG0840	transmembrane signaling receptor activity
F126LOC_RS20970	COG0840	transmembrane signaling receptor activity
F126LOC_RS20975	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F126LOC_RS20980	COG0583	DNA-binding transcription factor activity
F126LOC_RS21000	COG3157	Type VI secretion system effector, Hcp
F126LOC_RS21010	COG1045	serine acetyltransferase
F126LOC_RS21015	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F126LOC_RS21020	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
F126LOC_RS21025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F126LOC_RS21030	COG4942	peptidase
F126LOC_RS21035	COG2861	carbohydrate metabolic process
F126LOC_RS21040	COG1063	alcohol dehydrogenase
F126LOC_RS21045	COG0156	8-amino-7-oxononanoate synthase activity
F126LOC_RS21050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F126LOC_RS21060	COG0859	PFAM glycosyl transferase family 9
F126LOC_RS21065	COG0859	PFAM glycosyl transferase family 9
F126LOC_RS21080	COG1519	Transferase
F126LOC_RS21085	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F126LOC_RS21090	COG0859	PFAM glycosyl transferase family 9
F126LOC_RS21095	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F126LOC_RS21105	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F126LOC_RS21110	COG2003	Belongs to the UPF0758 family
F126LOC_RS21115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F126LOC_RS21120	COG0756	dUTP diphosphatase activity
F126LOC_RS21125	COG1309	transcriptional regulator
F126LOC_RS21130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F126LOC_RS21135	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
F126LOC_RS21140	COG4948	Mandelate Racemase Muconate Lactonizing
F126LOC_RS21145	COG4172	Belongs to the ABC transporter superfamily
F126LOC_RS21150	COG0747	negative chemotaxis
F126LOC_RS21155	COG0601	transmembrane transport
F126LOC_RS21160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F126LOC_RS21175	COG1446	asparaginase
F126LOC_RS21180	COG0583	DNA-binding transcription factor activity
F126LOC_RS21185	COG1561	YicC-like family, N-terminal region
F126LOC_RS21225	COG1396	sequence-specific DNA binding
F126LOC_RS21250	COG3157	Type VI secretion system effector, Hcp
F126LOC_RS21295	COG0628	permease
F126LOC_RS21300	COG1304	FMN binding
F126LOC_RS21305	COG1012	belongs to the aldehyde dehydrogenase family
F126LOC_RS21315	COG3239	Fatty acid desaturase
F126LOC_RS21345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F126LOC_RS21350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F126LOC_RS21355	COG3136	membrane protein required for alginate biosynthesis
F126LOC_RS21380	COG4677	pectinesterase activity
F126LOC_RS21385	COG2771	luxR family
F126LOC_RS21395	COG0137	argininosuccinate synthase activity
F126LOC_RS21405	COG2207	Transcriptional regulator
F126LOC_RS21405	COG1609	Transcriptional regulator
F126LOC_RS21410	COG4214	carbohydrate transport
F126LOC_RS21415	COG1129	ABC transporter
F126LOC_RS21420	COG4213	ABC transporter substrate-binding protein
F126LOC_RS21425	COG2115	Belongs to the xylose isomerase family
F126LOC_RS21430	COG1070	Carbohydrate kinase
F126LOC_RS21435	COG3274	enterobacterial common antigen metabolic process
F126LOC_RS21440	COG1012	belongs to the aldehyde dehydrogenase family
F126LOC_RS21445	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F126LOC_RS21450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F126LOC_RS21455	COG0840	transmembrane signaling receptor activity
F126LOC_RS21465	COG3722	fumarate hydratase activity
F126LOC_RS21470	COG0246	Mannitol dehydrogenase
F126LOC_RS21475	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F126LOC_RS21475	COG2213	PTS system mannitol-specific
F126LOC_RS21485	COG0751	glycine-tRNA ligase activity
F126LOC_RS21490	COG0752	glycyl-tRNA synthetase alpha subunit
F126LOC_RS21495	COG0730	response to heat
F126LOC_RS21500	COG2818	Glycosylase
F126LOC_RS21505	COG0456	acetyltransferase
F126LOC_RS21510	COG0840	transmembrane signaling receptor activity
F126LOC_RS21515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F126LOC_RS21530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F126LOC_RS21535	COG4172	Belongs to the ABC transporter superfamily
F126LOC_RS21540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F126LOC_RS21550	COG3479	Phenolic acid decarboxylase
F126LOC_RS21565	COG3550	peptidyl-serine autophosphorylation
F126LOC_RS21570	COG3550	peptidyl-serine autophosphorylation
F126LOC_RS21575	COG1280	lysine exporter protein (LysE YggA)
F126LOC_RS21580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F126LOC_RS21600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F126LOC_RS21605	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F126LOC_RS21625	COG2214	Heat shock protein DnaJ domain protein
F126LOC_RS21630	COG0443	Heat shock 70 kDa protein
F126LOC_RS21645	COG3712	iron ion homeostasis
F126LOC_RS21650	COG1595	DNA-templated transcription, initiation
F126LOC_RS21655	COG1629	transport
F126LOC_RS21665	COG0742	ribosomal rna small subunit methyltransferase
F126LOC_RS21670	COG0737	Belongs to the 5'-nucleotidase family
F126LOC_RS21680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F126LOC_RS21685	COG0589	response to stress
F126LOC_RS21695	COG0306	phosphate transporter
F126LOC_RS21700	COG2081	HI0933 family
F126LOC_RS21705	COG2200	EAL domain
F126LOC_RS21720	COG2194	sulfuric ester hydrolase activity
F126LOC_RS21725	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F126LOC_RS21730	COG0194	GDP metabolic process
F126LOC_RS21735	COG1758	RNA polymerase activity
F126LOC_RS21740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F126LOC_RS21745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F126LOC_RS21750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F126LOC_RS21755	COG2233	PERMEase
F126LOC_RS21760	COG2982	Protein involved in outer membrane biogenesis
F126LOC_RS21765	COG0456	acetyltransferase
F126LOC_RS21770	COG1490	D-aminoacyl-tRNA deacylase activity
F126LOC_RS21775	COG1011	Hydrolase
F126LOC_RS21790	COG3852	Histidine kinase
F126LOC_RS21810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F126LOC_RS21820	COG3078	GTPase activator activity
F126LOC_RS21825	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F126LOC_RS21830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F126LOC_RS21830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F126LOC_RS21840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F126LOC_RS21845	COG3084	Protein conserved in bacteria
F126LOC_RS21850	COG0746	molybdenum cofactor guanylyltransferase activity
F126LOC_RS21855	COG1763	Mo-molybdopterin cofactor biosynthetic process
F126LOC_RS21880	COG1609	Transcriptional regulator
F126LOC_RS21885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F126LOC_RS21895	COG1172	Belongs to the binding-protein-dependent transport system permease family
F126LOC_RS21900	COG1129	ABC transporter
F126LOC_RS21905	COG1869	D-ribose catabolic process
F126LOC_RS21910	COG3111	PFAM Bacterial OB fold (BOF) protein
F126LOC_RS21920	COG0642	Histidine kinase
F126LOC_RS21925	COG3158	transport of potassium into the cell
F126LOC_RS21930	COG0714	Associated with various cellular activities
F126LOC_RS21935	COG2425	protein containing a von Willebrand factor type A (vWA) domain
F126LOC_RS21940	COG2502	aspartate--ammonia ligase
F126LOC_RS21945	COG1522	sequence-specific DNA binding
F126LOC_RS21950	COG0716	FMN binding
F126LOC_RS21955	COG0445	tRNA wobble uridine modification
F126LOC_RS21960	COG0357	Ribosomal RNA small subunit methyltransferase G
F126LOC_RS21965	COG3312	ion transport
F126LOC_RS21970	COG0356	it plays a direct role in the translocation of protons across the membrane
F126LOC_RS21980	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F126LOC_RS21985	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F126LOC_RS21990	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F126LOC_RS21995	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F126LOC_RS22000	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F126LOC_RS22005	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F126LOC_RS22010	COG3385	transposase activity
F126LOC_RS22020	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F126LOC_RS22025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F126LOC_RS22050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F126LOC_RS22055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F126LOC_RS22065	COG0318	PFAM AMP-dependent synthetase and ligase
F126LOC_RS22070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F126LOC_RS22070	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
F126LOC_RS22075	COG1216	Glycosyl transferase, family 2
F126LOC_RS22110	COG1028	Short-chain dehydrogenase reductase Sdr
F126LOC_RS22125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F126LOC_RS22130	COG0573	inorganic phosphate transmembrane transporter activity
F126LOC_RS22135	COG0581	inorganic phosphate transmembrane transporter activity
F126LOC_RS22140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F126LOC_RS22150	COG1396	sequence-specific DNA binding
F126LOC_RS22155	COG3135	benzoate transporter
F126LOC_RS22160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F126LOC_RS22165	COG0765	amino acid transport
F126LOC_RS22170	COG0765	amino acid transport
F126LOC_RS22175	COG3547	Transposase (IS116 IS110 IS902 family)
F126LOC_RS22180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F126LOC_RS22185	COG2252	PERMEase
F126LOC_RS22190	COG2091	lysine biosynthetic process via aminoadipic acid
F126LOC_RS22195	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F126LOC_RS22200	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F126LOC_RS22200	COG0493	'glutamate synthase
F126LOC_RS22230	COG1733	regulation of RNA biosynthetic process
F126LOC_RS22235	COG0702	epimerase
F126LOC_RS22245	COG1396	sequence-specific DNA binding
F126LOC_RS22250	COG3550	peptidyl-serine autophosphorylation
F126LOC_RS22255	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
F126LOC_RS22260	COG0706	membrane insertase activity
F126LOC_RS22270	COG0594	ribonuclease P activity
F126LOC_RS22275	COG0230	Belongs to the bacterial ribosomal protein bL34 family