locus-tag	class	description
CTV95_RS00005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTV95_RS00015	COG0101	tRNA pseudouridine synthase activity
CTV95_RS00020	COG0586	Pfam SNARE associated Golgi protein
CTV95_RS00035	COG0285	dihydrofolate synthase activity
CTV95_RS00040	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CTV95_RS00045	COG1286	toxin biosynthetic process
CTV95_RS00050	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CTV95_RS00055	COG0163	prenyltransferase activity
CTV95_RS00070	COG4160	amino acid transport
CTV95_RS00075	COG4598	ABC transporter
CTV95_RS00085	COG1090	epimerase
CTV95_RS00090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CTV95_RS00095	COG0625	glutathione transferase activity
CTV95_RS00100	COG0622	Phosphoesterase
CTV95_RS00105	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CTV95_RS00110	COG3739	integral membrane protein
CTV95_RS00115	COG0857	belongs to the CobB CobQ family
CTV95_RS00115	COG0280	phosphate acetyltransferase
CTV95_RS00120	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CTV95_RS00125	COG3092	negative regulation of chromosome organization
CTV95_RS00130	COG3013	Belongs to the UPF0304 family
CTV95_RS00135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTV95_RS00140	COG0490	domain, Protein
CTV95_RS00140	COG0471	metal ion transport
CTV95_RS00145	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CTV95_RS00150	COG0436	Aminotransferase
CTV95_RS00155	COG0583	DNA-binding transcription factor activity
CTV95_RS00165	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTV95_RS00170	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTV95_RS00170	COG0649	NAD binding
CTV95_RS00175	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CTV95_RS00190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CTV95_RS00195	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTV95_RS00200	COG0839	Belongs to the complex I subunit 6 family
CTV95_RS00205	COG0713	ATP synthesis coupled electron transport
CTV95_RS00210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTV95_RS00215	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTV95_RS00220	COG1007	ATP synthesis coupled electron transport
CTV95_RS00225	COG4575	ribosome binding
CTV95_RS00230	COG0366	Alpha amylase catalytic
CTV95_RS00235	COG1263	PTS System
CTV95_RS00235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTV95_RS00250	COG0488	(ABC) transporter
CTV95_RS00260	COG4771	TonB-dependent receptor
CTV95_RS00295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTV95_RS00295	COG0519	Catalyzes the synthesis of GMP from XMP
CTV95_RS00300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTV95_RS00305	COG3058	Necessary for formate dehydrogenase activity
CTV95_RS00315	COG2149	membrane
CTV95_RS00320	COG4890	Cyd operon protein YbgT
CTV95_RS00325	COG1294	oxidase, subunit
CTV95_RS00330	COG1271	oxidase subunit
CTV95_RS00335	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CTV95_RS00350	COG3707	response regulator
CTV95_RS00365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTV95_RS00375	COG1116	anion transmembrane transporter activity
CTV95_RS00380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTV95_RS00380	COG2146	nitrite reductase [NAD(P)H] activity
CTV95_RS00385	COG0243	molybdopterin cofactor binding
CTV95_RS00390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTV95_RS00390	COG1648	precorrin-2 dehydrogenase activity
CTV95_RS00395	COG5464	transposase or invertase
CTV95_RS00400	COG4807	Protein conserved in bacteria
CTV95_RS00405	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CTV95_RS00415	COG1129	ABC transporter
CTV95_RS00420	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTV95_RS00425	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTV95_RS00435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTV95_RS00440	COG1070	Carbohydrate kinase
CTV95_RS00445	COG0640	Transcriptional regulator
CTV95_RS00450	COG1902	pentaerythritol trinitrate reductase activity
CTV95_RS00505	COG0745	RESPONSE REGULATOR receiver
CTV95_RS00560	COG0765	amino acid transport
CTV95_RS00565	COG0765	amino acid transport
CTV95_RS00580	COG5000	phosphorelay sensor kinase activity
CTV95_RS00580	COG5002	protein histidine kinase activity
CTV95_RS00585	COG0745	RESPONSE REGULATOR receiver
CTV95_RS00605	COG4948	Mandelate Racemase Muconate Lactonizing
CTV95_RS00615	COG0659	secondary active sulfate transmembrane transporter activity
CTV95_RS00620	COG0481	GTPase activity
CTV95_RS00630	COG2951	lytic endotransglycosylase activity
CTV95_RS00650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTV95_RS00655	COG2814	Major facilitator Superfamily
CTV95_RS00680	COG0656	L-ascorbic acid biosynthetic process
CTV95_RS00695	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CTV95_RS00725	COG2814	Major facilitator Superfamily
CTV95_RS00740	COG0667	Aldo Keto reductase
CTV95_RS00750	COG1560	Kdo2-lipid A biosynthetic process
CTV95_RS00760	COG3459	Glycosyltransferase 36 associated
CTV95_RS00765	COG1278	Cold shock
CTV95_RS00770	COG1278	Cold shock
CTV95_RS00785	COG2207	Transcriptional regulator
CTV95_RS00790	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTV95_RS00795	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTV95_RS00800	COG0667	Aldo Keto reductase
CTV95_RS00815	COG1902	pentaerythritol trinitrate reductase activity
CTV95_RS00830	COG1073	alpha beta
CTV95_RS00840	COG5002	protein histidine kinase activity
CTV95_RS00865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CTV95_RS00875	COG0582	viral genome integration into host DNA
CTV95_RS00895	COG1113	amino acid transport
CTV95_RS00915	COG2197	response regulator
CTV95_RS00920	COG0322	excinuclease ABC activity
CTV95_RS00925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTV95_RS00980	COG3706	GGDEF domain
CTV95_RS00990	COG0840	transmembrane signaling receptor activity
CTV95_RS00995	COG0697	spore germination
CTV95_RS01020	COG2198	Histidine kinase
CTV95_RS01020	COG0643	Histidine kinase
CTV95_RS01025	COG0835	chemotaxis
CTV95_RS01030	COG0840	transmembrane signaling receptor activity
CTV95_RS01035	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CTV95_RS01040	COG2201	protein-glutamate methylesterase activity
CTV95_RS01045	COG0745	RESPONSE REGULATOR receiver
CTV95_RS01055	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CTV95_RS01060	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CTV95_RS01075	COG2747	anti-sigma28 factor FlgM
CTV95_RS01085	COG1815	bacterial-type flagellum-dependent cell motility
CTV95_RS01090	COG1558	bacterial-type flagellum-dependent cell motility
CTV95_RS01095	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CTV95_RS01100	COG1749	Flagellar hook protein flgE
CTV95_RS01105	COG4787	bacterial-type flagellum-dependent cell motility
CTV95_RS01115	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CTV95_RS01120	COG1706	bacterial-type flagellum-dependent cell motility
CTV95_RS01170	COG1580	Controls the rotational direction of flagella during chemotaxis
CTV95_RS01190	COG1317	bacterial-type flagellum organization
CTV95_RS01205	COG1677	Flagellar hook-basal body complex protein FliE
CTV95_RS01230	COG0500	methyltransferase
CTV95_RS01270	COG1191	sigma factor activity
CTV95_RS01280	COG1702	phosphate starvation-inducible protein PhoH
CTV95_RS01295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTV95_RS01300	COG1309	transcriptional regulator
CTV95_RS01305	COG1012	belongs to the aldehyde dehydrogenase family
CTV95_RS01310	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CTV95_RS01315	COG2979	Protein of unknown function (DUF533)
CTV95_RS01320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CTV95_RS01325	COG1067	ATP-dependent peptidase activity
CTV95_RS01340	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
CTV95_RS01345	COG3070	regulator of competence-specific genes
CTV95_RS01350	COG1289	transmembrane transporter activity
CTV95_RS01355	COG3304	Inner membrane component domain
CTV95_RS01360	COG0210	DNA helicase
CTV95_RS01365	COG1803	Methylglyoxal synthase
CTV95_RS01375	COG1832	CoA-binding protein
CTV95_RS01380	COG3785	DNA binding
CTV95_RS01385	COG1254	Belongs to the acylphosphatase family
CTV95_RS01390	COG2920	part of a sulfur-relay system
CTV95_RS01395	COG0670	Belongs to the BI1 family
CTV95_RS01425	COG0589	response to stress
CTV95_RS01445	COG0840	transmembrane signaling receptor activity
CTV95_RS01460	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CTV95_RS01465	COG2943	transferase activity, transferring hexosyl groups
CTV95_RS01470	COG1560	Kdo2-lipid A biosynthetic process
CTV95_RS01475	COG1902	pentaerythritol trinitrate reductase activity
CTV95_RS01480	COG1054	Belongs to the UPF0176 family
CTV95_RS01485	COG2353	YceI-like domain
CTV95_RS01490	COG3038	cytochrome b561
CTV95_RS01510	COG0418	dihydroorotase activity
CTV95_RS01520	COG1530	ribonuclease E activity
CTV95_RS01520	COG1530	ribonuclease E activity
CTV95_RS01525	COG0564	pseudouridine synthase activity
CTV95_RS01530	COG0424	maF-like protein
CTV95_RS01535	COG1399	metal-binding, possibly nucleic acid-binding protein
CTV95_RS01540	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CTV95_RS01545	COG0416	fatty acid biosynthetic process
CTV95_RS01550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CTV95_RS01555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CTV95_RS01565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTV95_RS01570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTV95_RS01575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CTV95_RS01580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CTV95_RS01585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CTV95_RS01590	COG0470	DNA polymerase III
CTV95_RS01595	COG0084	hydrolase, TatD family'
CTV95_RS01600	COG1263	PTS System
CTV95_RS01600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTV95_RS01610	COG0477	Major facilitator Superfamily
CTV95_RS01615	COG0537	adenosine 5'-monophosphoramidase activity
CTV95_RS01625	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CTV95_RS01635	COG1472	Belongs to the glycosyl hydrolase 3 family
CTV95_RS01640	COG3150	esterase
CTV95_RS01645	COG1252	NADH dehydrogenase
CTV95_RS01650	COG3134	Outer membrane lipoprotein
CTV95_RS01665	COG1309	transcriptional regulator
CTV95_RS01670	COG0443	Heat shock 70 kDa protein
CTV95_RS01675	COG3547	Transposase (IS116 IS110 IS902 family)
CTV95_RS01680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CTV95_RS01685	COG4591	ABC-type transport system involved in lipoprotein release permease component
CTV95_RS01690	COG1136	(ABC) transporter
CTV95_RS01695	COG4591	ABC-type transport system involved in lipoprotein release permease component
CTV95_RS01700	COG1940	carbohydrate kinase activity
CTV95_RS01725	COG2226	methyltransferase
CTV95_RS01730	COG4139	cobalamin transport
CTV95_RS01735	COG0386	Belongs to the glutathione peroxidase family
CTV95_RS01740	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CTV95_RS01745	COG0791	NLP P60 protein
CTV95_RS01750	COG0095	Lipoate-protein ligase
CTV95_RS01755	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CTV95_RS01760	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CTV95_RS01765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTV95_RS01770	COG4558	Periplasmic binding protein
CTV95_RS01775	COG3720	iron ion transport
CTV95_RS01780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTV95_RS01785	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CTV95_RS01790	COG0574	Belongs to the PEP-utilizing enzyme family
CTV95_RS01790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CTV95_RS01795	COG1477	protein flavinylation
CTV95_RS01805	COG0628	permease
CTV95_RS01810	COG0247	lactate metabolic process
CTV95_RS01810	COG0277	FAD linked oxidase domain protein
CTV95_RS01815	COG2050	protein possibly involved in aromatic compounds catabolism
CTV95_RS01825	COG0316	Belongs to the HesB IscA family
CTV95_RS01830	COG0719	Fe-S assembly protein
CTV95_RS01835	COG0396	ATPase activity
CTV95_RS01840	COG0719	Fe-S assembly protein
CTV95_RS01845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTV95_RS01850	COG2166	iron-sulfur cluster assembly
CTV95_RS01855	COG1388	LysM domain
CTV95_RS01855	COG1376	ErfK ybiS ycfS ynhG family protein
CTV95_RS01860	COG4238	major outer membrane lipoprotein
CTV95_RS01895	COG2382	esterase
CTV95_RS01905	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CTV95_RS01910	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CTV95_RS01915	COG0437	4 iron, 4 sulfur cluster binding
CTV95_RS01920	COG3301	Polysulphide reductase, NrfD
CTV95_RS01925	COG1138	Cytochrome C-type biogenesis protein
CTV95_RS01930	COG3088	subunit of a heme lyase
CTV95_RS01935	COG4235	cytochrome complex assembly
CTV95_RS01940	COG4133	protoheme IX ABC transporter activity
CTV95_RS01945	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CTV95_RS01950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CTV95_RS01955	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CTV95_RS01960	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CTV95_RS01965	COG1138	Cytochrome C-type biogenesis protein
CTV95_RS01970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTV95_RS01975	COG4235	cytochrome complex assembly
CTV95_RS01975	COG3088	subunit of a heme lyase
CTV95_RS01980	COG3088	subunit of a heme lyase
CTV95_RS01980	COG4235	cytochrome complex assembly
CTV95_RS01985	COG3005	denitrification pathway
CTV95_RS01990	COG3043	anaerobic respiration
CTV95_RS01995	COG0348	domain, Protein
CTV95_RS02000	COG0437	4 iron, 4 sulfur cluster binding
CTV95_RS02005	COG0243	molybdopterin cofactor binding
CTV95_RS02010	COG3062	negative regulation of establishment of protein localization
CTV95_RS02015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTV95_RS02015	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTV95_RS02025	COG3850	Histidine kinase
CTV95_RS02030	COG2197	response regulator
CTV95_RS02055	COG2076	Multidrug Resistance protein
CTV95_RS02060	COG0561	phosphatase activity
CTV95_RS02070	COG1408	metallophosphoesterase
CTV95_RS02075	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CTV95_RS02100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTV95_RS02105	COG1116	anion transmembrane transporter activity
CTV95_RS02110	COG3665	Urea carboxylase-associated protein
CTV95_RS02120	COG0439	Biotin carboxylase
CTV95_RS02135	COG0534	Mate efflux family protein
CTV95_RS02140	COG0307	riboflavin synthase, alpha
CTV95_RS02145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTV95_RS02150	COG1609	Transcriptional regulator
CTV95_RS02160	COG0791	NLP P60 protein
CTV95_RS02165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CTV95_RS02170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTV95_RS02175	COG0346	lactoylglutathione lyase activity
CTV95_RS02180	COG3313	Fe-S protein
CTV95_RS02195	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CTV95_RS02200	COG3895	Periplasmic Protein
CTV95_RS02205	COG0259	pyridoxamine-phosphate oxidase activity
CTV95_RS02210	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CTV95_RS02215	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CTV95_RS02220	COG0625	glutathione transferase activity
CTV95_RS02225	COG1301	dicarboxylic acid transport
CTV95_RS02235	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CTV95_RS02245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTV95_RS02250	COG0671	phosphoesterase, PA-phosphatase related
CTV95_RS02255	COG1879	ABC-type sugar transport system periplasmic component
CTV95_RS02265	COG1129	ABC transporter
CTV95_RS02270	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTV95_RS02275	COG3959	Transketolase, thiamine diphosphate binding domain
CTV95_RS02280	COG3958	Transketolase
CTV95_RS02285	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTV95_RS02290	COG1082	Xylose isomerase domain protein TIM barrel
CTV95_RS02300	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CTV95_RS02305	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CTV95_RS02310	COG0284	orotidine-5'-phosphate decarboxylase activity
CTV95_RS02315	COG0023	Translation Initiation Factor
CTV95_RS02325	COG0235	Class ii aldolase
CTV95_RS02330	COG1966	Carbon starvation protein
CTV95_RS02335	COG4989	oxidoreductase activity
CTV95_RS02340	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CTV95_RS02345	COG0243	molybdopterin cofactor binding
CTV95_RS02350	COG0583	DNA-binding transcription factor activity
CTV95_RS02360	COG2271	Major facilitator Superfamily
CTV95_RS02400	COG4171	peptide transport system, permease
CTV95_RS02410	COG4166	transmembrane transport
CTV95_RS02430	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CTV95_RS02435	COG1842	Phage shock protein A
CTV95_RS02445	COG1983	PspC domain protein
CTV95_RS02460	COG3210	domain, Protein
CTV95_RS02470	COG2831	hemolysin activation secretion protein
CTV95_RS02475	COG3106	COG3106 Predicted ATPase
CTV95_RS02480	COG3768	UPF0283 membrane protein
CTV95_RS02495	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CTV95_RS02500	COG2866	Carboxypeptidase
CTV95_RS02505	COG4166	transmembrane transport
CTV95_RS02510	COG0598	Magnesium transport protein CorA
CTV95_RS02515	COG0037	tRNA processing
CTV95_RS02545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CTV95_RS02550	COG0840	transmembrane signaling receptor activity
CTV95_RS02555	COG0840	transmembrane signaling receptor activity
CTV95_RS02560	COG2911	Protein conserved in bacteria
CTV95_RS02570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTV95_RS02575	COG1643	Atp-dependent helicase
CTV95_RS02585	COG5001	Diguanylate cyclase
CTV95_RS02585	COG3300	MHYT domain
CTV95_RS02590	COG3591	Belongs to the peptidase S1B family
CTV95_RS02605	COG2205	protein histidine kinase activity
CTV95_RS02610	COG0745	RESPONSE REGULATOR receiver
CTV95_RS02640	COG1028	Short-chain dehydrogenase reductase Sdr
CTV95_RS02650	COG0659	secondary active sulfate transmembrane transporter activity
CTV95_RS02655	COG0387	Pfam Sodium calcium exchanger
CTV95_RS02670	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CTV95_RS02685	COG2197	response regulator
CTV95_RS02690	COG3850	Histidine kinase
CTV95_RS02695	COG2223	nitrite transmembrane transporter activity
CTV95_RS02700	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CTV95_RS02705	COG1140	nitrate reductase beta subunit
CTV95_RS02710	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CTV95_RS02715	COG2181	nitrate reductase activity
CTV95_RS02720	COG0697	spore germination
CTV95_RS02725	COG1846	Transcriptional regulator
CTV95_RS02765	COG3328	transposase activity
CTV95_RS02795	COG2261	transglycosylase associated protein
CTV95_RS02810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTV95_RS02825	COG1028	Short-chain dehydrogenase reductase Sdr
CTV95_RS02830	COG3842	ATPase activity
CTV95_RS02840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTV95_RS02845	COG1012	belongs to the aldehyde dehydrogenase family
CTV95_RS02855	COG1176	ABC-type spermidine putrescine transport system, permease component I
CTV95_RS02865	COG1028	Short-chain dehydrogenase reductase Sdr
CTV95_RS02875	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTV95_RS02885	COG0671	phosphoesterase, PA-phosphatase related
CTV95_RS02890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTV95_RS02895	COG2011	ABC-type metal ion transport system permease component
CTV95_RS02900	COG4948	Mandelate Racemase Muconate Lactonizing
CTV95_RS02905	COG1464	Belongs to the NlpA lipoprotein family
CTV95_RS02925	COG0583	DNA-binding transcription factor activity
CTV95_RS02930	COG4792	protein secretion
CTV95_RS02940	COG4794	Type iii secretion
CTV95_RS02965	COG1157	protein secretion by the type III secretion system
CTV95_RS02990	COG3850	Histidine kinase
CTV95_RS02995	COG2197	response regulator
CTV95_RS03005	COG2200	EAL domain
CTV95_RS03020	COG4669	(LipO)protein
CTV95_RS03065	COG3501	Rhs element vgr protein
CTV95_RS03135	COG1802	Transcriptional regulator
CTV95_RS03140	COG2831	hemolysin activation secretion protein
CTV95_RS03175	COG3210	domain, Protein
CTV95_RS03255	COG1802	Transcriptional regulator
CTV95_RS03275	COG1129	ABC transporter
CTV95_RS03295	COG0640	Transcriptional regulator
CTV95_RS03300	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CTV95_RS03310	COG1126	abc transporter atp-binding protein
CTV95_RS03315	COG0765	amino acid transport
CTV95_RS03325	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CTV95_RS03335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTV95_RS03345	COG3547	Transposase (IS116 IS110 IS902 family)
CTV95_RS03350	COG1473	amidohydrolase
CTV95_RS03355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTV95_RS03370	COG2234	aminopeptidase activity
CTV95_RS03375	COG1609	Transcriptional regulator
CTV95_RS03380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTV95_RS03380	COG1263	PTS System
CTV95_RS03385	COG2723	6-phospho-beta-galactosidase activity
CTV95_RS03390	COG0483	inositol monophosphate 1-phosphatase activity
CTV95_RS03395	COG0346	lactoylglutathione lyase activity
CTV95_RS03400	COG3443	Belongs to the bacterial solute-binding protein 9 family
CTV95_RS03405	COG0523	cobalamin synthesis protein
CTV95_RS03425	COG2755	lipolytic protein G-D-S-L family
CTV95_RS03440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTV95_RS03475	COG3958	Transketolase
CTV95_RS03480	COG3959	Transketolase, thiamine diphosphate binding domain
CTV95_RS03485	COG1028	Short-chain dehydrogenase reductase Sdr
CTV95_RS03490	COG2271	Major facilitator Superfamily
CTV95_RS03495	COG0583	DNA-binding transcription factor activity
CTV95_RS03500	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CTV95_RS03510	COG0582	viral genome integration into host DNA
CTV95_RS03685	COG3451	type IV secretory pathway VirB4
CTV95_RS03725	COG2977	Belongs to the P-Pant transferase superfamily
CTV95_RS03730	COG2814	Major facilitator Superfamily
CTV95_RS03755	COG1028	Short-chain dehydrogenase reductase Sdr
CTV95_RS03790	COG1309	transcriptional regulator
CTV95_RS03805	COG0582	viral genome integration into host DNA
CTV95_RS03810	COG0012	GTP binding
CTV95_RS03815	COG0193	aminoacyl-tRNA hydrolase activity
CTV95_RS03825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTV95_RS03830	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CTV95_RS03835	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CTV95_RS03840	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CTV95_RS03845	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CTV95_RS03850	COG2890	protein-(glutamine-N5) methyltransferase activity
CTV95_RS03860	COG2912	Transglutaminase-like superfamily
CTV95_RS03865	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CTV95_RS03875	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CTV95_RS03880	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CTV95_RS03890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTV95_RS03895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTV95_RS03900	COG0673	inositol 2-dehydrogenase activity
CTV95_RS03915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTV95_RS03950	COG4305	rare lipoprotein A
CTV95_RS03955	COG1764	response to oxidative stress
CTV95_RS03960	COG3783	Cytochrome b(562)
CTV95_RS03970	COG0738	Major facilitator superfamily
CTV95_RS03975	COG0456	acetyltransferase
CTV95_RS04010	COG1028	Short-chain dehydrogenase reductase Sdr
CTV95_RS04035	COG4628	conserved protein (DUF2132)
CTV95_RS04040	COG1649	PFAM Uncharacterised BCR, COG1649
CTV95_RS04050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTV95_RS04055	COG0076	glutamate decarboxylase activity
CTV95_RS04065	COG1942	4-Oxalocrotonate Tautomerase
CTV95_RS04080	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CTV95_RS04095	COG1215	transferase activity, transferring glycosyl groups
CTV95_RS04100	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CTV95_RS04105	COG4221	oxidoreductase activity
CTV95_RS04125	COG0477	Major facilitator Superfamily
CTV95_RS04130	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CTV95_RS04135	COG1940	carbohydrate kinase activity
CTV95_RS04140	COG0583	DNA-binding transcription factor activity
CTV95_RS04145	COG2814	Major facilitator Superfamily
CTV95_RS04155	COG0114	fumarate hydratase activity
CTV95_RS04160	COG1482	cell wall glycoprotein biosynthetic process
CTV95_RS04165	COG5339	Protein conserved in bacteria
CTV95_RS04175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTV95_RS04185	COG0385	Bile acid
CTV95_RS04190	COG0673	inositol 2-dehydrogenase activity
CTV95_RS04205	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTV95_RS04210	COG1129	ABC transporter
CTV95_RS04215	COG1879	ABC-type sugar transport system periplasmic component
CTV95_RS04220	COG1069	ribulokinase activity
CTV95_RS04225	COG2160	L-arabinose isomerase activity
CTV95_RS04235	COG4657	Part of a membrane complex involved in electron transport
CTV95_RS04240	COG2878	Part of a membrane complex involved in electron transport
CTV95_RS04245	COG4656	Part of a membrane complex involved in electron transport
CTV95_RS04250	COG4658	electron transport chain
CTV95_RS04255	COG4659	FMN binding
CTV95_RS04265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CTV95_RS04270	COG3104	oligopeptide transport
CTV95_RS04290	COG0616	signal peptide processing
CTV95_RS04295	COG1028	Short-chain dehydrogenase reductase Sdr
CTV95_RS04300	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CTV95_RS04305	COG1187	pseudouridine synthase activity
CTV95_RS04310	COG0009	L-threonylcarbamoyladenylate synthase
CTV95_RS04315	COG0613	PHP domain protein
CTV95_RS04325	COG0512	Glutamine amidotransferase of anthranilate synthase
CTV95_RS04330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTV95_RS04335	COG0135	phosphoribosylanthranilate isomerase activity
CTV95_RS04335	COG0134	indole-3-glycerol-phosphate synthase activity
CTV95_RS04340	COG0133	tryptophan synthase activity
CTV95_RS04345	COG0159	tryptophan synthase activity
CTV95_RS04350	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CTV95_RS04355	COG3047	cAMP biosynthetic process
CTV95_RS04365	COG2917	probably involved in intracellular septation
CTV95_RS04370	COG1607	acyl-coa hydrolase
CTV95_RS04380	COG2350	Protein conserved in bacteria
CTV95_RS04395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTV95_RS04400	COG3099	Belongs to the UPF0263 family
CTV95_RS04410	COG0444	Belongs to the ABC transporter superfamily
CTV95_RS04415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTV95_RS04420	COG0601	transmembrane transport
CTV95_RS04435	COG1012	belongs to the aldehyde dehydrogenase family
CTV95_RS04435	COG1454	alcohol dehydrogenase
CTV95_RS04440	COG1435	thymidine kinase activity
CTV95_RS04450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTV95_RS04455	COG0745	RESPONSE REGULATOR receiver
CTV95_RS04460	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTV95_RS04465	COG3012	SEC-C Motif Domain Protein
CTV95_RS04470	COG0788	formyltetrahydrofolate deformylase activity
CTV95_RS04490	COG2860	membrane
CTV95_RS04495	COG0708	Exodeoxyribonuclease III
CTV95_RS04505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CTV95_RS04510	COG0778	Nitroreductase
CTV95_RS04515	COG0616	signal peptide processing
CTV95_RS04520	COG0252	asparaginase activity
CTV95_RS04525	COG1335	isochorismatase
CTV95_RS04530	COG3139	Protein of unknown function (DUF1315)
CTV95_RS04535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CTV95_RS04550	COG0656	L-ascorbic acid biosynthetic process
CTV95_RS04555	COG3713	MltA-interacting MipA family protein
CTV95_RS04560	COG2766	serine protein kinase
CTV95_RS04565	COG2718	Belongs to the UPF0229 family
CTV95_RS04580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTV95_RS04585	COG0205	6-phosphofructokinase activity
CTV95_RS04605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTV95_RS04615	COG3684	Belongs to the aldolase LacD family
CTV95_RS04620	COG2719	SpoVR family
CTV95_RS04625	COG2186	Transcriptional regulator
CTV95_RS04630	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CTV95_RS04635	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CTV95_RS04645	COG2983	Belongs to the UPF0260 family
CTV95_RS04650	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTV95_RS04655	COG3100	YcgL domain-containing protein
CTV95_RS04660	COG0850	regulation of cytokinetic process
CTV95_RS04665	COG2894	cell division
CTV95_RS04670	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CTV95_RS04675	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CTV95_RS04680	COG0318	PFAM AMP-dependent synthetase and ligase
CTV95_RS04685	COG3065	identical protein binding
CTV95_RS04695	COG1199	ATP-dependent helicase activity
CTV95_RS04700	COG0251	oxidation-reduction process
CTV95_RS04705	COG3140	Belongs to the UPF0181 family
CTV95_RS04715	COG0494	nUDIX hydrolase
CTV95_RS04720	COG1760	l-serine dehydratase
CTV95_RS04725	COG1253	flavin adenine dinucleotide binding
CTV95_RS04730	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTV95_RS04730	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTV95_RS04735	COG3715	PTS system
CTV95_RS04740	COG3716	PTS system mannose fructose sorbose family IID component
CTV95_RS04745	COG4811	Protein of unknown function (DUF986)
CTV95_RS04750	COG1971	Probably functions as a manganese efflux pump
CTV95_RS04755	COG2226	methyltransferase
CTV95_RS04770	COG0803	Belongs to the bacterial solute-binding protein 9 family
CTV95_RS04775	COG1121	(ABC) transporter
CTV95_RS04780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTV95_RS04785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTV95_RS04790	COG3001	Fructosamine kinase
CTV95_RS04800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTV95_RS04805	COG1917	Cupin 2, conserved barrel domain protein
CTV95_RS04810	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CTV95_RS04815	COG1028	Short-chain dehydrogenase reductase Sdr
CTV95_RS04825	COG1175	transmembrane transport
CTV95_RS04830	COG0395	ABC-type sugar transport system, permease component
CTV95_RS04835	COG3842	ATPase activity
CTV95_RS04845	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CTV95_RS04850	COG2755	lipolytic protein G-D-S-L family
CTV95_RS04850	COG0657	acetylesterase activity
CTV95_RS04855	COG1988	membrane-bound metal-dependent
CTV95_RS04860	COG1823	symporter activity
CTV95_RS04865	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTV95_RS04870	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTV95_RS04880	COG1132	(ABC) transporter
CTV95_RS04890	COG0776	regulation of translation
CTV95_RS04895	COG0072	phenylalanine-tRNA ligase activity
CTV95_RS04895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTV95_RS04900	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CTV95_RS04905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CTV95_RS04910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CTV95_RS04915	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CTV95_RS04920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CTV95_RS04925	COG1113	amino acid transport
CTV95_RS04940	COG0823	Involved in the tonB-independent uptake of proteins
CTV95_RS04945	COG0501	Belongs to the peptidase M48B family
CTV95_RS04955	COG1653	transport
CTV95_RS04960	COG2223	nitrite transmembrane transporter activity
CTV95_RS04965	COG3279	Response regulator of the LytR AlgR family
CTV95_RS04970	COG3275	phosphorelay sensor kinase activity
CTV95_RS04995	COG0348	domain, Protein
CTV95_RS05000	COG0538	isocitrate dehydrogenase activity
CTV95_RS05005	COG1187	pseudouridine synthase activity
CTV95_RS05015	COG0482	sulfurtransferase activity
CTV95_RS05020	COG2915	High frequency lysogenization protein hflD homolog
CTV95_RS05025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CTV95_RS05045	COG2850	peptidyl-arginine hydroxylation
CTV95_RS05050	COG2195	Cleaves the N-terminal amino acid of tripeptides
CTV95_RS05055	COG3842	ATPase activity
CTV95_RS05065	COG1177	transmembrane transport
CTV95_RS05075	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTV95_RS05080	COG2223	nitrite transmembrane transporter activity
CTV95_RS05095	COG2207	Transcriptional regulator
CTV95_RS05105	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CTV95_RS05110	COG1956	GAF domain-containing protein
CTV95_RS05115	COG2995	paraquat-inducible protein a
CTV95_RS05120	COG3008	intermembrane lipid transfer
CTV95_RS05125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CTV95_RS05125	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CTV95_RS05140	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CTV95_RS05150	COG1278	Cold shock
CTV95_RS05160	COG1528	Iron-storage protein
CTV95_RS05170	COG1770	oligopeptidase
CTV95_RS05175	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CTV95_RS05180	COG0800	Aldolase
CTV95_RS05185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CTV95_RS05190	COG1737	Transcriptional regulator
CTV95_RS05195	COG0469	pyruvate kinase activity
CTV95_RS05200	COG1560	Kdo2-lipid A biosynthetic process
CTV95_RS05205	COG0739	heme binding
CTV95_RS05210	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CTV95_RS05215	COG1121	(ABC) transporter
CTV95_RS05220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTV95_RS05225	COG1609	Transcriptional regulator
CTV95_RS05230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTV95_RS05235	COG1447	Phosphotransferase system cellobiose-specific component IIA
CTV95_RS05240	COG4580	involved in the transport of maltose and maltodextrins
CTV95_RS05245	COG2255	four-way junction helicase activity
CTV95_RS05250	COG0632	four-way junction helicase activity
CTV95_RS05255	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CTV95_RS05260	COG0217	transcriptional regulatory protein
CTV95_RS05265	COG0494	nUDIX hydrolase
CTV95_RS05270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CTV95_RS05275	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CTV95_RS05280	COG1801	Protein of unknown function DUF72
CTV95_RS05285	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CTV95_RS05290	COG2226	methyltransferase
CTV95_RS05295	COG0500	methyltransferase
CTV95_RS05300	COG3142	Participates in the control of copper homeostasis
CTV95_RS05305	COG3102	Protein conserved in bacteria
CTV95_RS05310	COG0018	arginyl-trna synthetase
CTV95_RS05315	COG0728	peptidoglycan biosynthetic process
CTV95_RS05325	COG3132	Protein of unknown function, DUF480
CTV95_RS05330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTV95_RS05335	COG0477	Major facilitator Superfamily
CTV95_RS05340	COG2999	glutathione oxidoreductase activity
CTV95_RS05350	COG3381	protein complex oligomerization
CTV95_RS05355	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CTV95_RS05395	COG0840	transmembrane signaling receptor activity
CTV95_RS05400	COG3130	regulation of translation
CTV95_RS05405	COG3009	Protein conserved in bacteria
CTV95_RS05410	COG3008	intermembrane lipid transfer
CTV95_RS05410	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CTV95_RS05415	COG2995	paraquat-inducible protein a
CTV95_RS05420	COG0488	(ABC) transporter
CTV95_RS05425	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CTV95_RS05425	COG0116	Belongs to the methyltransferase superfamily
CTV95_RS05430	COG3217	Mosc domain protein beta barrel domain protein
CTV95_RS05430	COG0633	Ferredoxin
CTV95_RS05440	COG0167	dihydroorotate dehydrogenase activity
CTV95_RS05445	COG0308	aminopeptidase N
CTV95_RS05450	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CTV95_RS05455	COG0017	Asparaginyl-tRNA synthetase
CTV95_RS05465	COG1448	Aminotransferase
CTV95_RS05470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTV95_RS05475	COG3108	Peptidase M15
CTV95_RS05480	COG2989	Protein conserved in bacteria
CTV95_RS05485	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CTV95_RS05490	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CTV95_RS05495	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CTV95_RS05500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTV95_RS05505	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CTV95_RS05510	COG3173	Aminoglycoside phosphotransferase
CTV95_RS05520	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CTV95_RS05525	COG2835	tetraacyldisaccharide 4'-kinase activity
CTV95_RS05535	COG1663	tetraacyldisaccharide 4'-kinase activity
CTV95_RS05540	COG1132	(ABC) transporter
CTV95_RS05545	COG2333	competence protein COMEC
CTV95_RS05545	COG0658	competence protein
CTV95_RS05550	COG2926	Belongs to the UPF0265 family
CTV95_RS05555	COG4604	ABC transporter, ATP-binding protein
CTV95_RS05560	COG4605	iron ion homeostasis
CTV95_RS05570	COG4607	ABC-type enterochelin transport system periplasmic component
CTV95_RS05575	COG2925	Exonuclease
CTV95_RS05580	COG0531	amino acid
CTV95_RS05590	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CTV95_RS05595	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CTV95_RS05615	COG3052	prosthetic group binding
CTV95_RS05620	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CTV95_RS05625	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTV95_RS05630	COG3493	citrate carrier protein
CTV95_RS05640	COG4565	transcriptional regulatory protein
CTV95_RS05645	COG0840	transmembrane signaling receptor activity
CTV95_RS05650	COG0840	transmembrane signaling receptor activity
CTV95_RS05655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTV95_RS05660	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CTV95_RS05665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CTV95_RS05670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CTV95_RS05675	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CTV95_RS05675	COG0131	Imidazoleglycerol-phosphate dehydratase
CTV95_RS05680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CTV95_RS05685	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CTV95_RS05690	COG0107	imidazoleglycerol-phosphate synthase activity
CTV95_RS05695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CTV95_RS05695	COG0140	phosphoribosyl-ATP diphosphatase activity
CTV95_RS05700	COG0776	regulation of translation
CTV95_RS05705	COG0539	negative regulation of cytoplasmic translation
CTV95_RS05710	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CTV95_RS05715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CTV95_RS05720	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CTV95_RS05725	COG1944	ATP diphosphatase activity
CTV95_RS05730	COG2116	formate transmembrane transporter activity
CTV95_RS05735	COG1882	Formate acetyltransferase
CTV95_RS05740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CTV95_RS05765	COG2814	Major facilitator Superfamily
CTV95_RS05770	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CTV95_RS05775	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTV95_RS05780	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CTV95_RS05785	COG1674	ftsk spoiiie
CTV95_RS05785	COG3107	peptidoglycan biosynthetic process
CTV95_RS05795	COG0492	ferredoxin-NADP+ reductase activity
CTV95_RS05800	COG4988	ABC transporter
CTV95_RS05805	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CTV95_RS05810	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CTV95_RS05815	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CTV95_RS05825	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTV95_RS05830	COG0542	response to heat
CTV95_RS05835	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CTV95_RS05845	COG1278	Cold shock
CTV95_RS05850	COG3593	DNA synthesis involved in DNA repair
CTV95_RS05855	COG2431	L-lysine efflux transmembrane transporter activity
CTV95_RS05860	COG1151	hydroxylamine reductase activity
CTV95_RS05865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTV95_RS05870	COG0702	epimerase
CTV95_RS05875	COG3023	N-Acetylmuramoyl-L-alanine amidase
CTV95_RS05880	COG0393	Putative heavy-metal-binding
CTV95_RS05885	COG1126	abc transporter atp-binding protein
CTV95_RS05890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTV95_RS05895	COG4215	(ABC) transporter
CTV95_RS05900	COG4160	amino acid transport
CTV95_RS05905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTV95_RS05915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CTV95_RS05925	COG1177	transmembrane transport
CTV95_RS05930	COG1176	ABC-type spermidine putrescine transport system, permease component I
CTV95_RS05935	COG3842	ATPase activity
CTV95_RS05940	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CTV95_RS05950	COG0189	ligase activity
CTV95_RS05955	COG0778	Nitroreductase
CTV95_RS05970	COG2985	domain, Protein
CTV95_RS05970	COG0569	domain protein
CTV95_RS05980	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CTV95_RS05985	COG1349	DNA-binding transcription factor activity
CTV95_RS05990	COG1686	Belongs to the peptidase S11 family
CTV95_RS05995	COG2011	ABC-type metal ion transport system permease component
CTV95_RS06000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTV95_RS06010	COG0625	glutathione transferase activity
CTV95_RS06015	COG2133	pyrroloquinoline quinone binding
CTV95_RS06020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CTV95_RS06025	COG2949	membrane
CTV95_RS06030	COG2311	Membrane
CTV95_RS06035	COG0302	gtp cyclohydrolase
CTV95_RS06040	COG0840	transmembrane signaling receptor activity
CTV95_RS06045	COG0583	DNA-binding transcription factor activity
CTV95_RS06070	COG0371	Dehydrogenase
CTV95_RS06075	COG1129	ABC transporter
CTV95_RS06080	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTV95_RS06085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CTV95_RS06090	COG4771	TonB-dependent receptor
CTV95_RS06095	COG0833	amino acid
CTV95_RS06100	COG0583	DNA-binding transcription factor activity
CTV95_RS06105	COG2855	membrane
CTV95_RS06115	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CTV95_RS06120	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CTV95_RS06120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTV95_RS06120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTV95_RS06125	COG1105	Belongs to the carbohydrate kinase PfkB family
CTV95_RS06130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTV95_RS06130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTV95_RS06145	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CTV95_RS06150	COG0523	cobalamin synthesis protein
CTV95_RS06155	COG0671	phosphoesterase, PA-phosphatase related
CTV95_RS06160	COG0791	NLP P60 protein
CTV95_RS06165	COG4166	transmembrane transport
CTV95_RS06170	COG4174	ABC transporter (Permease)
CTV95_RS06175	COG4239	(ABC) transporter, permease
CTV95_RS06180	COG4172	Belongs to the ABC transporter superfamily
CTV95_RS06190	COG2814	Major facilitator Superfamily
CTV95_RS06205	COG1061	Type III restriction enzyme res subunit
CTV95_RS06210	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CTV95_RS06220	COG3081	Nucleoid-associated protein
CTV95_RS06225	COG3082	Protein of unknown function (DUF1414)
CTV95_RS06230	COG3083	sulfuric ester hydrolase activity
CTV95_RS06240	COG0582	viral genome integration into host DNA
CTV95_RS06320	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CTV95_RS06330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CTV95_RS06335	COG0534	Mate efflux family protein
CTV95_RS06340	COG2807	transmembrane transport
CTV95_RS06345	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CTV95_RS06355	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CTV95_RS06355	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CTV95_RS06360	COG0783	Belongs to the Dps family
CTV95_RS06365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTV95_RS06370	COG0765	amino acid transport
CTV95_RS06375	COG1126	abc transporter atp-binding protein
CTV95_RS06385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTV95_RS06460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTV95_RS06555	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CTV95_RS06570	COG1686	Belongs to the peptidase S11 family
CTV95_RS06595	COG2040	homocysteine
CTV95_RS06600	COG0833	amino acid
CTV95_RS06605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTV95_RS06610	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CTV95_RS06615	COG0747	negative chemotaxis
CTV95_RS06620	COG2195	Cleaves the N-terminal amino acid of tripeptides
CTV95_RS06625	COG2207	Transcriptional regulator
CTV95_RS06625	COG3708	Transcriptional regulator
CTV95_RS06635	COG0513	Belongs to the DEAD box helicase family
CTV95_RS06645	COG1120	ATPase activity
CTV95_RS06650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTV95_RS06655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTV95_RS06660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTV95_RS06675	COG1131	(ABC) transporter
CTV95_RS06680	COG0842	Transport permease protein
CTV95_RS06685	COG0842	Transport permease protein
CTV95_RS06690	COG0670	Belongs to the BI1 family
CTV95_RS06695	COG0314	molybdopterin synthase activity
CTV95_RS06700	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CTV95_RS06705	COG0315	cyclic pyranopterin monophosphate synthase activity
CTV95_RS06710	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTV95_RS06715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CTV95_RS06730	COG0556	nucleotide-excision repair
CTV95_RS06735	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CTV95_RS06740	COG2226	methyltransferase
CTV95_RS06745	COG0156	8-amino-7-oxononanoate synthase activity
CTV95_RS06750	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CTV95_RS06760	COG5297	Belongs to the glycosyl hydrolase family 6
CTV95_RS06765	COG1380	Effector of murein hydrolase LrgA
CTV95_RS06770	COG1346	cytolysis
CTV95_RS06775	COG0295	cytidine deaminase activity
CTV95_RS06780	COG0281	malic enzyme
CTV95_RS06785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTV95_RS06790	COG0601	transmembrane transport
CTV95_RS06795	COG0747	negative chemotaxis
CTV95_RS06800	COG4172	Belongs to the ABC transporter superfamily
CTV95_RS06805	COG0303	'Molybdopterin
CTV95_RS06810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CTV95_RS06830	COG0401	homolog of Blt101
CTV95_RS06850	COG3228	Belongs to the MtfA family
CTV95_RS06880	COG4227	nucleotidyltransferase activity
CTV95_RS06885	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CTV95_RS06885	COG0517	IMP dehydrogenase activity
CTV95_RS06890	COG2723	6-phospho-beta-galactosidase activity
CTV95_RS06900	COG3226	Transcriptional regulator
CTV95_RS06905	COG0738	Major facilitator superfamily
CTV95_RS06925	COG0582	viral genome integration into host DNA
CTV95_RS06945	COG3272	Protein of unknown function (DUF1722)
CTV95_RS06965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTV95_RS06980	COG0300	oxidoreductase activity
CTV95_RS06990	COG0789	Transcriptional regulator
CTV95_RS07020	COG3122	Protein conserved in bacteria
CTV95_RS07030	COG2723	6-phospho-beta-galactosidase activity
CTV95_RS07035	COG0789	Transcriptional regulator
CTV95_RS07035	COG4978	Transcriptional regulator
CTV95_RS07040	COG2814	Major facilitator Superfamily
CTV95_RS07045	COG0640	Transcriptional regulator
CTV95_RS07050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTV95_RS07065	COG1733	regulation of RNA biosynthetic process
CTV95_RS07070	COG2910	NAD(P)H-binding
CTV95_RS07075	COG0625	glutathione transferase activity
CTV95_RS07080	COG2814	Major facilitator Superfamily
CTV95_RS07085	COG3226	Transcriptional regulator
CTV95_RS07095	COG0835	chemotaxis
CTV95_RS07095	COG0784	Response regulator, receiver
CTV95_RS07110	COG2995	paraquat-inducible protein a
CTV95_RS07115	COG3008	intermembrane lipid transfer
CTV95_RS07115	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CTV95_RS07135	COG1132	(ABC) transporter
CTV95_RS07140	COG2375	cellular response to nickel ion
CTV95_RS07140	COG1132	(ABC) transporter
CTV95_RS07160	COG4771	TonB-dependent receptor
CTV95_RS07180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTV95_RS07195	COG5464	transposase or invertase
CTV95_RS07200	COG0444	Belongs to the ABC transporter superfamily
CTV95_RS07215	COG0747	negative chemotaxis
CTV95_RS07220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTV95_RS07225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CTV95_RS07235	COG0477	Major facilitator Superfamily
CTV95_RS07245	COG2226	methyltransferase
CTV95_RS07255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTV95_RS07260	COG1012	belongs to the aldehyde dehydrogenase family
CTV95_RS07300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CTV95_RS07305	COG0371	Dehydrogenase
CTV95_RS07310	COG1301	dicarboxylic acid transport
CTV95_RS07325	COG0697	spore germination
CTV95_RS07330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTV95_RS07335	COG1136	(ABC) transporter
CTV95_RS07335	COG0577	efflux transmembrane transporter activity
CTV95_RS07345	COG1136	(ABC) transporter
CTV95_RS07345	COG0577	efflux transmembrane transporter activity
CTV95_RS07360	COG0672	)-iron permease
CTV95_RS07370	COG3383	formate dehydrogenase (NAD+) activity
CTV95_RS07375	COG2851	Citrate transporter
CTV95_RS07385	COG1301	dicarboxylic acid transport
CTV95_RS07390	COG0583	DNA-binding transcription factor activity
CTV95_RS07405	COG1464	Belongs to the NlpA lipoprotein family
CTV95_RS07420	COG2271	Major facilitator Superfamily
CTV95_RS07425	COG1840	ABC-type Fe3 transport system, periplasmic component
CTV95_RS07435	COG3842	ATPase activity
CTV95_RS07440	COG1609	Transcriptional regulator
CTV95_RS07445	COG3250	beta-galactosidase activity
CTV95_RS07450	COG2223	nitrite transmembrane transporter activity
CTV95_RS07460	COG0582	viral genome integration into host DNA
CTV95_RS07475	COG3423	Transcriptional regulator
CTV95_RS07495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CTV95_RS07545	COG3736	Type IV secretory pathway, component VirB8
CTV95_RS07550	COG3504	Conjugal transfer protein
CTV95_RS07560	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CTV95_RS07610	COG1074	ATP-dependent DNA helicase activity
CTV95_RS07630	COG0582	viral genome integration into host DNA
CTV95_RS07645	COG4227	nucleotidyltransferase activity
CTV95_RS07655	COG0582	viral genome integration into host DNA
CTV95_RS07675	COG2910	NAD(P)H-binding
CTV95_RS07680	COG0583	DNA-binding transcription factor activity
CTV95_RS07690	COG0583	DNA-binding transcription factor activity
CTV95_RS07700	COG3615	Tellurite resistance protein tehB
CTV95_RS07710	COG2199	diguanylate cyclase activity
CTV95_RS07710	COG2203	Gaf domain
CTV95_RS07715	COG2190	(PTS) system
CTV95_RS07715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTV95_RS07715	COG1263	PTS System
CTV95_RS07720	COG2723	6-phospho-beta-galactosidase activity
CTV95_RS07730	COG1840	ABC-type Fe3 transport system, periplasmic component
CTV95_RS07735	COG4208	sulfate ABC transporter
CTV95_RS07740	COG3842	ATPase activity
CTV95_RS07755	COG3718	enzyme involved in inositol metabolism
CTV95_RS07765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTV95_RS07775	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTV95_RS07790	COG0673	inositol 2-dehydrogenase activity
CTV95_RS07795	COG3962	Belongs to the TPP enzyme family
CTV95_RS07820	COG3706	GGDEF domain
CTV95_RS07825	COG3711	transcriptional antiterminator
CTV95_RS07830	COG2723	6-phospho-beta-galactosidase activity
CTV95_RS07840	COG1605	Chorismate mutase
CTV95_RS07845	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTV95_RS07870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTV95_RS07880	COG1215	transferase activity, transferring glycosyl groups
CTV95_RS07890	COG1051	belongs to the nudix hydrolase family
CTV95_RS07895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTV95_RS07900	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CTV95_RS07920	COG0110	maltose O-acetyltransferase activity
CTV95_RS07930	COG1216	Glycosyl transferase, family 2
CTV95_RS07930	COG0463	Glycosyl transferase, family 2
CTV95_RS07935	COG2244	polysaccharide biosynthetic process
CTV95_RS07945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CTV95_RS07955	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CTV95_RS07975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CTV95_RS07980	COG1253	flavin adenine dinucleotide binding
CTV95_RS07985	COG3069	C4-dicarboxylate transmembrane transporter activity
CTV95_RS07990	COG2982	Protein involved in outer membrane biogenesis
CTV95_RS07995	COG0717	Belongs to the dCTP deaminase family
CTV95_RS08000	COG0572	uridine kinase
CTV95_RS08005	COG0489	protein tyrosine kinase activity
CTV95_RS08010	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTV95_RS08010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTV95_RS08015	COG3383	formate dehydrogenase (NAD+) activity
CTV95_RS08015	COG0243	molybdopterin cofactor binding
CTV95_RS08020	COG0437	4 iron, 4 sulfur cluster binding
CTV95_RS08025	COG2864	formate dehydrogenase
CTV95_RS08040	COG2706	6-phosphogluconolactonase activity
CTV95_RS08050	COG0561	phosphatase activity
CTV95_RS08055	COG0837	glucose binding
CTV95_RS08060	COG2211	Major facilitator Superfamily
CTV95_RS08085	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CTV95_RS08090	COG4149	molybdate abc transporter
CTV95_RS08095	COG0725	ABC transporter, periplasmic molybdate-binding protein
CTV95_RS08105	COG2005	Transcriptional regulator
CTV95_RS08105	COG3585	molybdate ion transport
CTV95_RS08110	COG1119	ATPase activity
CTV95_RS08115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTV95_RS08120	COG2017	converts alpha-aldose to the beta-anomer
CTV95_RS08140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTV95_RS08145	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTV95_RS08150	COG0588	phosphoglycerate mutase activity
CTV95_RS08155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTV95_RS08160	COG1230	cation diffusion facilitator family transporter
CTV95_RS08170	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CTV95_RS08180	COG1811	Na channel or pump
CTV95_RS08195	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CTV95_RS08200	COG2885	chlorophyll binding
CTV95_RS08205	COG0823	Involved in the tonB-independent uptake of proteins
CTV95_RS08210	COG3064	Membrane
CTV95_RS08215	COG0848	biopolymer transport protein
CTV95_RS08220	COG0811	peptide transport
CTV95_RS08225	COG0824	Thioesterase
CTV95_RS08230	COG3790	cyd operon protein YbgE
CTV95_RS08235	COG4890	Cyd operon protein YbgT
CTV95_RS08240	COG1294	oxidase, subunit
CTV95_RS08245	COG1271	oxidase subunit
CTV95_RS08255	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CTV95_RS08260	COG0045	succinate-CoA ligase (ADP-forming) activity
CTV95_RS08265	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTV95_RS08270	COG0567	Dehydrogenase, E1 component
CTV95_RS08275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTV95_RS08280	COG1053	succinate dehydrogenase
CTV95_RS08285	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CTV95_RS08310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CTV95_RS08315	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CTV95_RS08320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CTV95_RS08325	COG1984	allophanate hydrolase subunit 2
CTV95_RS08330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CTV95_RS08335	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTV95_RS08340	COG0415	Belongs to the DNA photolyase family
CTV95_RS08345	COG3272	Protein of unknown function (DUF1722)
CTV95_RS08350	COG3842	ATPase activity
CTV95_RS08355	COG1840	ABC-type Fe3 transport system, periplasmic component
CTV95_RS08375	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CTV95_RS08380	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CTV95_RS08385	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CTV95_RS08390	COG2205	protein histidine kinase activity
CTV95_RS08395	COG0745	RESPONSE REGULATOR receiver
CTV95_RS08405	COG0033	Phosphoglucomutase
CTV95_RS08410	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CTV95_RS08415	COG0596	Alpha beta hydrolase
CTV95_RS08425	COG0840	transmembrane signaling receptor activity
CTV95_RS08430	COG0716	FMN binding
CTV95_RS08435	COG0735	belongs to the Fur family
CTV95_RS08440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTV95_RS08445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTV95_RS08445	COG2190	(PTS) system
CTV95_RS08445	COG1263	PTS System
CTV95_RS08450	COG0363	glucosamine-6-phosphate deaminase activity
CTV95_RS08455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CTV95_RS08460	COG1940	carbohydrate kinase activity
CTV95_RS08460	COG1846	Transcriptional regulator
CTV95_RS08465	COG0367	asparagine synthase
CTV95_RS08510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTV95_RS08515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CTV95_RS08520	COG1702	phosphate starvation-inducible protein PhoH
CTV95_RS08525	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CTV95_RS08535	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CTV95_RS08545	COG0765	amino acid transport
CTV95_RS08550	COG0765	amino acid transport
CTV95_RS08555	COG1126	abc transporter atp-binding protein
CTV95_RS08560	COG3547	Transposase (IS116 IS110 IS902 family)
CTV95_RS08565	COG2888	peptidyl-tyrosine sulfation
CTV95_RS08570	COG0495	leucyl-tRNA aminoacylation
CTV95_RS08575	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CTV95_RS08580	COG1466	dna polymerase III delta subunit
CTV95_RS08585	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CTV95_RS08590	COG0799	negative regulation of ribosome biogenesis
CTV95_RS08595	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CTV95_RS08600	COG0768	penicillin binding
CTV95_RS08605	COG0772	Belongs to the SEDS family
CTV95_RS08610	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CTV95_RS08615	COG1686	Belongs to the peptidase S11 family
CTV95_RS08620	COG2921	Belongs to the UPF0250 family
CTV95_RS08625	COG0321	lipoyl(octanoyl) transferase activity
CTV95_RS08630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTV95_RS08635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CTV95_RS08640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CTV95_RS08650	COG1794	racemase activity, acting on amino acids and derivatives
CTV95_RS08655	COG1393	Belongs to the ArsC family
CTV95_RS08660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTV95_RS08665	COG1876	peptidase activity
CTV95_RS08680	COG0400	carboxylic ester hydrolase activity
CTV95_RS08685	COG3813	Protein conserved in bacteria
CTV95_RS08695	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CTV95_RS08705	COG4178	(ABC) transporter
CTV95_RS08710	COG4774	siderophore transport
CTV95_RS08715	COG1595	DNA-templated transcription, initiation
CTV95_RS08720	COG3712	iron ion homeostasis
CTV95_RS08725	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CTV95_RS08740	COG0312	modulator of DNA gyrase
CTV95_RS08745	COG0312	modulator of DNA gyrase
CTV95_RS08750	COG3118	belongs to the thioredoxin family
CTV95_RS08755	COG1444	tRNA N-acetyltransferase activity
CTV95_RS08760	COG2707	UPF0756 membrane protein
CTV95_RS08765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CTV95_RS08770	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CTV95_RS08780	COG2716	regulation of RNA biosynthetic process
CTV95_RS08785	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CTV95_RS08790	COG4783	chaperone-mediated protein folding
CTV95_RS08795	COG1393	Belongs to the ArsC family
CTV95_RS08800	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CTV95_RS08805	COG2233	PERMEase
CTV95_RS08815	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CTV95_RS08820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CTV95_RS08825	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CTV95_RS08830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTV95_RS08840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTV95_RS08850	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CTV95_RS08855	COG4181	ATPase activity
CTV95_RS08860	COG2755	lipolytic protein G-D-S-L family
CTV95_RS08865	COG0300	oxidoreductase activity
CTV95_RS08870	COG3118	belongs to the thioredoxin family
CTV95_RS08885	COG0814	amino acid
CTV95_RS08905	COG1441	menaquinone biosynthetic process
CTV95_RS08910	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CTV95_RS08915	COG0596	Alpha beta hydrolase
CTV95_RS08920	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CTV95_RS08925	COG1169	isochorismate synthase
CTV95_RS08930	COG2223	nitrite transmembrane transporter activity
CTV95_RS08935	COG2198	Histidine kinase
CTV95_RS08935	COG0642	Histidine kinase
CTV95_RS08940	COG2197	response regulator
CTV95_RS08945	COG2205	protein histidine kinase activity
CTV95_RS08945	COG0784	Response regulator, receiver
CTV95_RS08955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTV95_RS08960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTV95_RS08965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTV95_RS08970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTV95_RS08975	COG0330	HflC and HflK could
CTV95_RS08980	COG1585	Membrane protein implicated in regulation of membrane protease activity
CTV95_RS08990	COG2217	Heavy metal translocating P-type atpase
CTV95_RS09005	COG3735	TraB family
CTV95_RS09020	COG5434	Belongs to the glycosyl hydrolase 28 family
CTV95_RS09025	COG0523	cobalamin synthesis protein
CTV95_RS09030	COG2879	small protein
CTV95_RS09035	COG1966	Carbon starvation protein
CTV95_RS09045	COG0737	Belongs to the 5'-nucleotidase family
CTV95_RS09050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTV95_RS09050	COG4651	solute:proton antiporter activity
CTV95_RS09055	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CTV95_RS09060	COG0563	adenylate kinase activity
CTV95_RS09065	COG0326	Molecular chaperone. Has ATPase activity
CTV95_RS09070	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CTV95_RS09075	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CTV95_RS09080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CTV95_RS09085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CTV95_RS09090	COG2832	Protein of unknown function (DUF454)
CTV95_RS09105	COG1309	transcriptional regulator
CTV95_RS09110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTV95_RS09115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTV95_RS09120	COG0254	rRNA binding
CTV95_RS09125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CTV95_RS09145	COG3695	enzyme binding
CTV95_RS09150	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CTV95_RS09155	COG1946	Acyl-CoA thioesterase
CTV95_RS09160	COG0004	ammonium transporteR
CTV95_RS09165	COG0347	Belongs to the P(II) protein family
CTV95_RS09170	COG1132	(ABC) transporter
CTV95_RS09175	COG1132	(ABC) transporter
CTV95_RS09180	COG1522	sequence-specific DNA binding
CTV95_RS09185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTV95_RS09190	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CTV95_RS09195	COG0824	Thioesterase
CTV95_RS09200	COG1555	photosystem II stabilization
CTV95_RS09205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTV95_RS09210	COG0776	regulation of translation
CTV95_RS09215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CTV95_RS09220	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CTV95_RS09225	COG0740	serine-type endopeptidase activity
CTV95_RS09230	COG0544	peptidyl-prolyl cis-trans isomerase activity
CTV95_RS09235	COG0271	Belongs to the BolA IbaG family
CTV95_RS09240	COG3056	Lipoprotein
CTV95_RS09245	COG2223	nitrite transmembrane transporter activity
CTV95_RS09250	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CTV95_RS09255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTV95_RS09260	COG1845	cytochrome c oxidase, subunit III
CTV95_RS09265	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CTV95_RS09270	COG0109	protoheme IX farnesyltransferase activity
CTV95_RS09280	COG2814	Major facilitator Superfamily
CTV95_RS09285	COG1666	GTP binding
CTV95_RS09290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CTV95_RS09300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CTV95_RS09300	COG0301	tRNA thio-modification
CTV95_RS09305	COG1722	exodeoxyribonuclease VII activity
CTV95_RS09310	COG0142	geranyltranstransferase activity
CTV95_RS09315	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CTV95_RS09320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CTV95_RS09325	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CTV95_RS09330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CTV95_RS09335	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CTV95_RS09340	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTV95_RS09340	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTV95_RS09345	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CTV95_RS09350	COG4238	major outer membrane lipoprotein
CTV95_RS09355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTV95_RS09360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTV95_RS09365	COG1862	Preprotein translocase
CTV95_RS09370	COG0343	queuine tRNA-ribosyltransferase activity
CTV95_RS09375	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CTV95_RS09380	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CTV95_RS09385	COG0450	alkyl hydroperoxide reductase
CTV95_RS09390	COG0668	transmembrane transport
CTV95_RS09400	COG1114	Component of the transport system for branched-chain amino acids
CTV95_RS09405	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CTV95_RS09430	COG0420	3'-5' exonuclease activity
CTV95_RS09435	COG0419	ATPase involved in DNA repair
CTV95_RS09440	COG1940	carbohydrate kinase activity
CTV95_RS09445	COG2974	May be involved in recombination
CTV95_RS09455	COG2188	Transcriptional regulator
CTV95_RS09460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTV95_RS09465	COG1397	ADP-ribosylglycohydrolase
CTV95_RS09470	COG2211	Major facilitator Superfamily
CTV95_RS09475	COG3123	guanosine phosphorylase activity
CTV95_RS09480	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CTV95_RS09490	COG4615	Cyclic peptide transporter
CTV95_RS09520	COG5297	Belongs to the glycosyl hydrolase family 6
CTV95_RS09525	COG1312	Catalyzes the dehydration of D-mannonate
CTV95_RS09535	COG2186	Transcriptional regulator
CTV95_RS09565	COG0583	DNA-binding transcription factor activity
CTV95_RS09575	COG2951	lytic endotransglycosylase activity
CTV95_RS09580	COG2824	Alkylphosphonate utilization operon protein PhnA
CTV95_RS09585	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CTV95_RS09590	COG1595	DNA-templated transcription, initiation
CTV95_RS09595	COG3712	iron ion homeostasis
CTV95_RS09600	COG4772	TonB-dependent receptor
CTV95_RS09605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CTV95_RS09610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTV95_RS09615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTV95_RS09620	COG1120	ATPase activity
CTV95_RS09655	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CTV95_RS09660	COG3015	lipoprotein NlpE involved in copper resistance
CTV95_RS09675	COG4568	rho-dependent transcription termination
CTV95_RS09680	COG0037	tRNA processing
CTV95_RS09685	COG0346	lactoylglutathione lyase activity
CTV95_RS09690	COG0825	malonyl-CoA metabolic process
CTV95_RS09695	COG0587	DNA-directed DNA polymerase activity
CTV95_RS09700	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CTV95_RS09705	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTV95_RS09710	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTV95_RS09715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CTV95_RS09720	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTV95_RS09725	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CTV95_RS09730	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTV95_RS09735	COG0750	zinc metalloprotease
CTV95_RS09740	COG0575	Belongs to the CDS family
CTV95_RS09745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CTV95_RS09750	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CTV95_RS09755	COG0233	cytoplasmic translational termination
CTV95_RS09760	COG0528	UMP kinase activity
CTV95_RS09765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CTV95_RS09770	COG0052	Belongs to the universal ribosomal protein uS2 family
CTV95_RS09780	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CTV95_RS09825	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CTV95_RS09825	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CTV95_RS09835	COG1611	Belongs to the LOG family
CTV95_RS09840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTV95_RS09845	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CTV95_RS09850	COG2363	Small membrane protein
CTV95_RS09855	COG0583	DNA-binding transcription factor activity
CTV95_RS09865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTV95_RS09870	COG2166	iron-sulfur cluster assembly
CTV95_RS09875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CTV95_RS09885	COG0747	negative chemotaxis
CTV95_RS09895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTV95_RS09900	COG4172	Belongs to the ABC transporter superfamily
CTV95_RS09905	COG1473	amidohydrolase
CTV95_RS09915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTV95_RS09920	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CTV95_RS09940	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTV95_RS09945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CTV95_RS09945	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CTV95_RS09955	COG1609	Transcriptional regulator
CTV95_RS09960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTV95_RS09965	COG1074	ATP-dependent DNA helicase activity
CTV95_RS09970	COG1025	Belongs to the peptidase M16 family
CTV95_RS09975	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CTV95_RS10005	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CTV95_RS10010	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CTV95_RS10020	COG0494	nUDIX hydrolase
CTV95_RS10030	COG3066	DNA modification
CTV95_RS10035	COG0861	Integral membrane protein TerC family
CTV95_RS10050	COG0667	Aldo Keto reductase
CTV95_RS10055	COG3639	organic phosphonate transmembrane transporter activity
CTV95_RS10065	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CTV95_RS10075	COG3454	Phosphonate metabolism
CTV95_RS10080	COG4778	phosphonate C-P lyase system protein PhnL
CTV95_RS10085	COG4107	phosphonate C-P lyase system protein PhnK
CTV95_RS10090	COG3627	carbon phosphorus lyase activity
CTV95_RS10095	COG3626	phosphonate metabolism
CTV95_RS10100	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CTV95_RS10105	COG3624	Phosphonate C-P lyase system protein PhnG
CTV95_RS10110	COG2188	Transcriptional regulator
CTV95_RS10115	COG1404	Belongs to the peptidase S8 family
CTV95_RS10125	COG3171	Protein conserved in bacteria
CTV95_RS10130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CTV95_RS10140	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CTV95_RS10145	COG0741	lytic transglycosylase activity
CTV95_RS10150	COG1917	Cupin 2, conserved barrel domain protein
CTV95_RS10150	COG2169	Transcriptional regulator
CTV95_RS10165	COG5564	TIM-barrel signal transduction protein
CTV95_RS10170	COG5441	Belongs to the UPF0261 family
CTV95_RS10190	COG1982	Orn Lys Arg decarboxylase major
CTV95_RS10205	COG0582	viral genome integration into host DNA
CTV95_RS10280	COG1045	serine acetyltransferase
CTV95_RS10295	COG0438	transferase activity, transferring glycosyl groups
CTV95_RS10300	COG0297	glycogen (starch) synthase activity
CTV95_RS10355	COG2207	Transcriptional regulator
CTV95_RS10360	COG2814	Major facilitator Superfamily
CTV95_RS10365	COG1846	Transcriptional regulator
CTV95_RS10410	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTV95_RS10475	COG3121	Chaperone
CTV95_RS10490	COG3550	peptidyl-serine autophosphorylation
CTV95_RS10505	COG4948	Mandelate Racemase Muconate Lactonizing
CTV95_RS10520	COG0583	DNA-binding transcription factor activity
CTV95_RS10540	COG2814	Major facilitator Superfamily
CTV95_RS10560	COG0811	peptide transport
CTV95_RS10575	COG1802	Transcriptional regulator
CTV95_RS10580	COG0246	Mannitol dehydrogenase
CTV95_RS10585	COG0477	Major facilitator Superfamily
CTV95_RS10595	COG1063	alcohol dehydrogenase
CTV95_RS10600	COG4948	Mandelate Racemase Muconate Lactonizing
CTV95_RS10610	COG4104	PAAR repeat-containing protein
CTV95_RS10620	COG0583	DNA-binding transcription factor activity
CTV95_RS10630	COG0437	4 iron, 4 sulfur cluster binding
CTV95_RS10635	COG3301	Polysulphide reductase, NrfD
CTV95_RS10640	COG0477	Major facilitator Superfamily
CTV95_RS10645	COG0431	NADPH-dependent FMN reductase
CTV95_RS10645	COG1053	succinate dehydrogenase
CTV95_RS10645	COG3976	FMN-binding domain protein
CTV95_RS10660	COG2169	Transcriptional regulator
CTV95_RS10660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTV95_RS10685	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTV95_RS10685	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTV95_RS10690	COG3604	Transcriptional regulator
CTV95_RS10695	COG0426	domain, Protein
CTV95_RS10695	COG1773	rubredoxin
CTV95_RS10700	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTV95_RS10710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTV95_RS10720	COG0531	amino acid
CTV95_RS10725	COG3115	cell septum assembly
CTV95_RS10730	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CTV95_RS10745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTV95_RS10755	COG2190	(PTS) system
CTV95_RS10760	COG2205	protein histidine kinase activity
CTV95_RS10765	COG0745	RESPONSE REGULATOR receiver
CTV95_RS10770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTV95_RS10775	COG1136	(ABC) transporter
CTV95_RS10775	COG0577	efflux transmembrane transporter activity
CTV95_RS10780	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTV95_RS10785	COG4208	sulfate ABC transporter
CTV95_RS10790	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CTV95_RS10795	COG4150	thiosulfate binding
CTV95_RS10800	COG2837	iron assimilation
CTV95_RS10810	COG4178	(ABC) transporter
CTV95_RS10815	COG0612	Peptidase, M16
CTV95_RS10820	COG4771	TonB-dependent receptor
CTV95_RS10830	COG0456	acetyltransferase
CTV95_RS10835	COG0408	coproporphyrinogen oxidase activity
CTV95_RS10840	COG1671	Belongs to the UPF0178 family
CTV95_RS10845	COG0814	amino acid
CTV95_RS10860	COG2084	Dehydrogenase
CTV95_RS10865	COG1082	Xylose isomerase domain protein TIM barrel
CTV95_RS10870	COG0149	triose-phosphate isomerase activity
CTV95_RS10875	COG2376	Dihydroxyacetone kinase
CTV95_RS10885	COG0698	ribose 5-phosphate isomerase
CTV95_RS10890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTV95_RS10895	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTV95_RS10900	COG2190	(PTS) system
CTV95_RS10900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTV95_RS10900	COG1263	PTS System
CTV95_RS10905	COG2723	6-phospho-beta-galactosidase activity
CTV95_RS10910	COG3711	transcriptional antiterminator
CTV95_RS10915	COG1609	Transcriptional regulator
CTV95_RS10945	COG0494	nUDIX hydrolase
CTV95_RS10960	COG0477	Major facilitator Superfamily
CTV95_RS10965	COG1942	4-Oxalocrotonate Tautomerase
CTV95_RS10970	COG1914	H( )-stimulated, divalent metal cation uptake system
CTV95_RS10975	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CTV95_RS10980	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CTV95_RS10985	COG0497	DNA recombination
CTV95_RS10995	COG2914	Belongs to the UPF0125 (RnfH) family
CTV95_RS11000	COG2867	negative regulation of translational initiation
CTV95_RS11005	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CTV95_RS11040	COG4453	Protein conserved in bacteria
CTV95_RS11060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTV95_RS11065	COG1280	lysine exporter protein (LysE YggA)
CTV95_RS11085	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTV95_RS11085	COG1013	pyruvate-flavodoxin oxidoreductase activity
CTV95_RS11085	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CTV95_RS11085	COG0674	pyruvate-flavodoxin oxidoreductase activity
CTV95_RS11090	COG3038	cytochrome b561
CTV95_RS11095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTV95_RS11100	COG1376	ErfK ybiS ycfS ynhG family protein
CTV95_RS11105	COG2873	o-acetylhomoserine
CTV95_RS11110	COG0246	Mannitol dehydrogenase
CTV95_RS11130	COG3712	iron ion homeostasis
CTV95_RS11140	COG4774	siderophore transport
CTV95_RS11155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTV95_RS11160	COG3162	membrane
CTV95_RS11165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTV95_RS11250	COG4964	Belongs to the GSP D family
CTV95_RS11270	COG5002	protein histidine kinase activity
CTV95_RS11270	COG3850	Histidine kinase
CTV95_RS11280	COG0025	NhaP-type Na H and K H
CTV95_RS11290	COG2252	PERMEase
CTV95_RS11315	COG1953	Uracil, thiamine, allantoin
CTV95_RS11320	COG1560	Kdo2-lipid A biosynthetic process
CTV95_RS11340	COG3157	Type VI secretion system effector, Hcp
CTV95_RS11380	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CTV95_RS11390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTV95_RS11395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTV95_RS11400	COG4974	Belongs to the 'phage' integrase family
CTV95_RS11405	COG0477	Major facilitator Superfamily
CTV95_RS11415	COG0716	FMN binding
CTV95_RS11425	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CTV95_RS11435	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CTV95_RS11440	COG0354	folic acid binding
CTV95_RS11445	COG1272	protein, Hemolysin III
CTV95_RS11465	COG2211	Major facilitator Superfamily
CTV95_RS11470	COG1653	transport
CTV95_RS11475	COG3842	ATPase activity
CTV95_RS11480	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTV95_RS11490	COG1175	transmembrane transport
CTV95_RS11500	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CTV95_RS11500	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CTV95_RS11505	COG0509	glycine decarboxylation via glycine cleavage system
CTV95_RS11510	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CTV95_RS11515	COG1454	alcohol dehydrogenase
CTV95_RS11565	COG0656	L-ascorbic acid biosynthetic process
CTV95_RS11570	COG2813	Specifically methylates the guanine in position
CTV95_RS11575	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CTV95_RS11580	COG0456	acetyltransferase
CTV95_RS11590	COG1595	DNA-templated transcription, initiation
CTV95_RS11595	COG3712	iron ion homeostasis
CTV95_RS11605	COG4178	(ABC) transporter
CTV95_RS11610	COG0813	purine-nucleoside phosphorylase activity
CTV95_RS11615	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CTV95_RS11620	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CTV95_RS11625	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CTV95_RS11630	COG1473	amidohydrolase
CTV95_RS11635	COG2827	Endonuclease containing a URI domain
CTV95_RS11640	COG3153	acetyltransferase
CTV95_RS11645	COG3154	lipid carrier protein
CTV95_RS11650	COG0826	peptidase U32
CTV95_RS11655	COG0826	peptidase U32
CTV95_RS11660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTV95_RS11665	COG0513	Belongs to the DEAD box helicase family
CTV95_RS11680	COG1185	polyribonucleotide nucleotidyltransferase activity
CTV95_RS11685	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CTV95_RS11690	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CTV95_RS11695	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CTV95_RS11700	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CTV95_RS11710	COG0779	Required for maturation of 30S ribosomal subunits
CTV95_RS11720	COG2197	response regulator
CTV95_RS11785	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CTV95_RS11790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTV95_RS11795	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CTV95_RS11800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTV95_RS11805	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CTV95_RS11810	COG1534	Rna-binding protein
CTV95_RS11820	COG2027	D-alanyl-D-alanine carboxypeptidase
CTV95_RS11825	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CTV95_RS11830	COG0697	spore germination
CTV95_RS11835	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CTV95_RS11840	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CTV95_RS11845	COG0142	geranyltranstransferase activity
CTV95_RS11860	COG3423	Transcriptional regulator
CTV95_RS11865	COG0039	L-malate dehydrogenase activity
CTV95_RS11870	COG1438	arginine binding
CTV95_RS11875	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CTV95_RS11880	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CTV95_RS11885	COG0358	DNA primase activity
CTV95_RS11895	COG3663	DNA glycosylase
CTV95_RS11905	COG2755	lipolytic protein G-D-S-L family
CTV95_RS11905	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CTV95_RS11910	COG0583	DNA-binding transcription factor activity
CTV95_RS11940	COG2199	diguanylate cyclase activity
CTV95_RS11945	COG3678	ATP-independent chaperone mediated protein folding
CTV95_RS11955	COG1902	pentaerythritol trinitrate reductase activity
CTV95_RS11955	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTV95_RS11960	COG2813	Specifically methylates the guanine in position
CTV95_RS11965	COG0673	inositol 2-dehydrogenase activity
CTV95_RS11970	COG0861	Integral membrane protein TerC family
CTV95_RS11975	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CTV95_RS11985	COG2721	sulfolactate sulfo-lyase activity
CTV95_RS11990	COG0246	Mannitol dehydrogenase
CTV95_RS11995	COG1904	glucuronate isomerase
CTV95_RS12000	COG2271	Major facilitator Superfamily
CTV95_RS12010	COG0586	Pfam SNARE associated Golgi protein
CTV95_RS12025	COG4575	ribosome binding
CTV95_RS12030	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CTV95_RS12040	COG2259	Doxx family
CTV95_RS12045	COG0435	Glutathione S-transferase
CTV95_RS12050	COG0583	DNA-binding transcription factor activity
CTV95_RS12055	COG1741	Belongs to the pirin family
CTV95_RS12060	COG0735	belongs to the Fur family
CTV95_RS12065	COG3237	CsbD-like
CTV95_RS12070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTV95_RS12075	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CTV95_RS12080	COG2937	Belongs to the GPAT DAPAT family
CTV95_RS12085	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CTV95_RS12095	COG0459	protein refolding
CTV95_RS12100	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CTV95_RS12115	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CTV95_RS12120	COG1324	tolerance protein
CTV95_RS12125	COG4232	protein-disulfide reductase activity
CTV95_RS12130	COG1309	transcriptional regulator
CTV95_RS12150	COG0582	viral genome integration into host DNA
CTV95_RS12220	COG3423	Transcriptional regulator
CTV95_RS12250	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CTV95_RS12255	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CTV95_RS12305	COG0300	oxidoreductase activity
CTV95_RS12305	COG0318	PFAM AMP-dependent synthetase and ligase
CTV95_RS12305	COG1028	Short-chain dehydrogenase reductase Sdr
CTV95_RS12305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTV95_RS12305	COG3321	synthase
CTV95_RS12315	COG1028	Short-chain dehydrogenase reductase Sdr
CTV95_RS12320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTV95_RS12325	COG1535	isochorismatase
CTV95_RS12325	COG3433	isochorismatase activity
CTV95_RS12330	COG1021	2,3-dihydroxybenzoate-AMP ligase
CTV95_RS12335	COG1169	isochorismate synthase
CTV95_RS12345	COG4771	TonB-dependent receptor
CTV95_RS12355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CTV95_RS12360	COG0084	hydrolase, TatD family'
CTV95_RS12370	COG5487	UPF0391 membrane protein
CTV95_RS12375	COG2823	Periplasmic or secreted lipoprotein
CTV95_RS12380	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CTV95_RS12390	COG3726	membrane protein affecting hemolysin expression
CTV95_RS12395	COG0560	Phosphoserine phosphatase
CTV95_RS12410	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTV95_RS12420	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CTV95_RS12425	COG3079	Belongs to the UPF0149 family
CTV95_RS12430	COG0006	proline dipeptidase activity
CTV95_RS12435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTV95_RS12440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTV95_RS12445	COG3157	Type VI secretion system effector, Hcp
CTV95_RS12475	COG2130	NADP-dependent
CTV95_RS12480	COG2862	Uncharacterized protein family, UPF0114
CTV95_RS12500	COG3477	response to acidic pH
CTV95_RS12505	COG0747	negative chemotaxis
CTV95_RS12510	COG0601	transmembrane transport
CTV95_RS12515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTV95_RS12535	COG4977	sequence-specific DNA binding
CTV95_RS12535	COG1917	Cupin 2, conserved barrel domain protein
CTV95_RS12540	COG1917	Cupin 2, conserved barrel domain protein
CTV95_RS12540	COG2169	Transcriptional regulator
CTV95_RS12545	COG1070	Carbohydrate kinase
CTV95_RS12550	COG4806	L-rhamnose isomerase
CTV95_RS12555	COG0235	Class ii aldolase
CTV95_RS12560	COG3254	rhamnose metabolic process
CTV95_RS12570	COG0840	transmembrane signaling receptor activity
CTV95_RS12580	COG0840	transmembrane signaling receptor activity
CTV95_RS12585	COG0288	reversible hydration of carbon dioxide
CTV95_RS12590	COG0659	secondary active sulfate transmembrane transporter activity
CTV95_RS12610	COG1690	Belongs to the RtcB family
CTV95_RS12615	COG4650	regulator
CTV95_RS12640	COG0583	DNA-binding transcription factor activity
CTV95_RS12660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTV95_RS12680	COG2850	peptidyl-arginine hydroxylation
CTV95_RS12760	COG0582	viral genome integration into host DNA
CTV95_RS12770	COG0795	lipopolysaccharide-transporting ATPase activity
CTV95_RS12775	COG0795	lipopolysaccharide-transporting ATPase activity
CTV95_RS12780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CTV95_RS12785	COG2927	DNA polymerase III (CHI subunit)
CTV95_RS12790	COG0525	valine-tRNA ligase activity
CTV95_RS12795	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CTV95_RS12800	COG0840	transmembrane signaling receptor activity
CTV95_RS12805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTV95_RS12810	COG0501	Belongs to the peptidase M48B family
CTV95_RS12830	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CTV95_RS12835	COG2731	YhcH YjgK YiaL family protein
CTV95_RS12840	COG0540	Belongs to the ATCase OTCase family
CTV95_RS12845	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CTV95_RS12865	COG0702	epimerase
CTV95_RS12870	COG3787	Belongs to the UPF0306 family
CTV95_RS12880	COG2814	Major facilitator Superfamily
CTV95_RS12885	COG0076	glutamate decarboxylase activity
CTV95_RS12895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTV95_RS12900	COG1518	maintenance of DNA repeat elements
CTV95_RS12915	COG1857	crispr-associated protein
CTV95_RS12935	COG1203	CRISPR-associated helicase, Cas3
CTV95_RS12970	COG0848	biopolymer transport protein
CTV95_RS12980	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CTV95_RS12995	COG0626	cystathionine gamma-synthase activity
CTV95_RS13000	COG0586	Pfam SNARE associated Golgi protein
CTV95_RS13005	COG2207	Transcriptional regulator
CTV95_RS13010	COG0778	Nitroreductase
CTV95_RS13015	COG1979	alcohol dehydrogenase
CTV95_RS13020	COG0656	L-ascorbic acid biosynthetic process
CTV95_RS13030	COG2132	Multicopper oxidase
CTV95_RS13035	COG0204	Acyl-transferase
CTV95_RS13040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CTV95_RS13050	COG1629	transport
CTV95_RS13050	COG4771	TonB-dependent receptor
CTV95_RS13055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTV95_RS13055	COG3711	transcriptional antiterminator
CTV95_RS13060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTV95_RS13060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTV95_RS13060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTV95_RS13065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTV95_RS13070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTV95_RS13070	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTV95_RS13090	COG0187	DNA topoisomerase II activity
CTV95_RS13095	COG3150	esterase
CTV95_RS13100	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTV95_RS13105	COG3151	Protein conserved in bacteria
CTV95_RS13110	COG0494	nUDIX hydrolase
CTV95_RS13125	COG5463	Belongs to the UPF0441 family
CTV95_RS13130	COG0754	glutathionylspermidine amidase activity
CTV95_RS13140	COG3384	dioxygenase
CTV95_RS13155	COG3385	transposase activity
CTV95_RS13165	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CTV95_RS13170	COG3107	peptidoglycan biosynthetic process
CTV95_RS13175	COG0792	nuclease activity
CTV95_RS13180	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CTV95_RS13185	COG2823	Periplasmic or secreted lipoprotein
CTV95_RS13195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTV95_RS13200	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CTV95_RS13205	COG5002	protein histidine kinase activity
CTV95_RS13205	COG0784	Response regulator, receiver
CTV95_RS13205	COG2198	Histidine kinase
CTV95_RS13210	COG1242	4 iron, 4 sulfur cluster binding
CTV95_RS13215	COG0070	glutamate synthase
CTV95_RS13215	COG0069	glutamate synthase activity
CTV95_RS13215	COG0067	glutamate synthase
CTV95_RS13220	COG0493	'glutamate synthase
CTV95_RS13235	COG2969	positive regulation of protein catabolic process
CTV95_RS13240	COG0625	glutathione transferase activity
CTV95_RS13245	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CTV95_RS13250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CTV95_RS13255	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CTV95_RS13260	COG3105	Protein conserved in bacteria
CTV95_RS13265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTV95_RS13270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTV95_RS13275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CTV95_RS13280	COG5007	Belongs to the BolA IbaG family
CTV95_RS13285	COG3113	response to antibiotic
CTV95_RS13290	COG2854	intermembrane phospholipid transfer
CTV95_RS13295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CTV95_RS13300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CTV95_RS13305	COG1127	ABC transporter
CTV95_RS13310	COG0530	calcium, potassium:sodium antiporter activity
CTV95_RS13315	COG0517	IMP dehydrogenase activity
CTV95_RS13315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CTV95_RS13320	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CTV95_RS13325	COG3117	lipopolysaccharide transmembrane transporter activity
CTV95_RS13330	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CTV95_RS13335	COG1137	ATPase activity
CTV95_RS13340	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CTV95_RS13345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CTV95_RS13350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTV95_RS13355	COG1660	Displays ATPase and GTPase activities
CTV95_RS13360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTV95_RS13365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTV95_RS13370	COG0312	modulator of DNA gyrase
CTV95_RS13375	COG3028	Belongs to the UPF0307 family
CTV95_RS13385	COG1289	transmembrane transporter activity
CTV95_RS13390	COG1566	PFAM secretion protein HlyD family protein
CTV95_RS13400	COG0583	DNA-binding transcription factor activity
CTV95_RS13415	COG0312	modulator of DNA gyrase
CTV95_RS13420	COG3164	Protein of unknown function
CTV95_RS13425	COG1530	ribonuclease E activity
CTV95_RS13430	COG0424	maF-like protein
CTV95_RS13435	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CTV95_RS13440	COG1792	Involved in formation and maintenance of cell shape
CTV95_RS13445	COG1077	Cell shape determining protein MreB Mrl
CTV95_RS13450	COG2200	EAL domain
CTV95_RS13450	COG2199	diguanylate cyclase activity
CTV95_RS13460	COG0604	alcohol dehydrogenase
CTV95_RS13465	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CTV95_RS13470	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CTV95_RS13475	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CTV95_RS13480	COG0511	ligase activity, forming carbon-carbon bonds
CTV95_RS13485	COG0439	Biotin carboxylase
CTV95_RS13490	COG2207	Transcriptional regulator
CTV95_RS13495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTV95_RS13505	COG3924	membrane
CTV95_RS13510	COG4145	pantothenate transmembrane transporter activity
CTV95_RS13515	COG2264	protein methyltransferase activity
CTV95_RS13530	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CTV95_RS13645	COG4964	Belongs to the GSP D family
CTV95_RS13680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTV95_RS13685	COG0765	amino acid transport
CTV95_RS13690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTV95_RS13695	COG4597	amino acid ABC transporter
CTV95_RS13700	COG0765	amino acid transport
CTV95_RS13705	COG1126	abc transporter atp-binding protein
CTV95_RS13735	COG0138	bifunctional purine biosynthesis protein purh
CTV95_RS13740	COG0151	Belongs to the GarS family
CTV95_RS13760	COG1515	deoxyribonuclease V activity
CTV95_RS13765	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CTV95_RS13770	COG2816	NAD+ diphosphatase activity
CTV95_RS13775	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CTV95_RS13780	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CTV95_RS13785	COG0352	thiamine-phosphate diphosphorylase activity
CTV95_RS13790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CTV95_RS13795	COG2104	thiamine diphosphate biosynthetic process
CTV95_RS13800	COG2022	thiamine diphosphate biosynthetic process
CTV95_RS13810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTV95_RS13815	COG5457	Domain of unknown function (DUF1127)
CTV95_RS13820	COG0477	Major facilitator Superfamily
CTV95_RS13825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CTV95_RS13830	COG0085	RNA polymerase activity
CTV95_RS13835	COG0222	ribosome binding
CTV95_RS13840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CTV95_RS13845	COG0081	regulation of translation
CTV95_RS13850	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CTV95_RS13855	COG0250	Participates in transcription elongation, termination and antitermination
CTV95_RS13900	COG1072	(Pantothenic acid kinase))
CTV95_RS13905	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CTV95_RS13905	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CTV95_RS13910	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CTV95_RS13955	COG1739	Uncharacterized protein family UPF0029
CTV95_RS13960	COG0006	proline dipeptidase activity
CTV95_RS13965	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTV95_RS13965	COG1024	Enoyl-CoA hydratase
CTV95_RS13970	COG0183	Belongs to the thiolase family
CTV95_RS13980	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CTV95_RS13985	COG0250	Participates in transcription elongation, termination and antitermination
CTV95_RS13995	COG0084	hydrolase, TatD family'
CTV95_RS14000	COG0805	protein transport
CTV95_RS14005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CTV95_RS14010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CTV95_RS14015	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTV95_RS14025	COG2226	methyltransferase
CTV95_RS14030	COG1322	Protein conserved in bacteria
CTV95_RS14035	COG0165	Argininosuccinate lyase
CTV95_RS14040	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CTV95_RS14045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CTV95_RS14050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTV95_RS14055	COG2188	Transcriptional regulator
CTV95_RS14060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTV95_RS14065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CTV95_RS14090	COG4948	Mandelate Racemase Muconate Lactonizing
CTV95_RS14095	COG2190	(PTS) system
CTV95_RS14095	COG1263	PTS System
CTV95_RS14095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTV95_RS14100	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CTV95_RS14125	COG0412	Dienelactone hydrolase
CTV95_RS14130	COG0840	transmembrane signaling receptor activity
CTV95_RS14135	COG0840	transmembrane signaling receptor activity
CTV95_RS14140	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CTV95_RS14145	COG0583	DNA-binding transcription factor activity
CTV95_RS14160	COG1045	serine acetyltransferase
CTV95_RS14165	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CTV95_RS14170	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CTV95_RS14175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CTV95_RS14180	COG4942	peptidase
CTV95_RS14185	COG2861	carbohydrate metabolic process
CTV95_RS14190	COG1063	alcohol dehydrogenase
CTV95_RS14195	COG0156	8-amino-7-oxononanoate synthase activity
CTV95_RS14200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTV95_RS14210	COG0859	PFAM glycosyl transferase family 9
CTV95_RS14215	COG0859	PFAM glycosyl transferase family 9
CTV95_RS14230	COG1519	Transferase
CTV95_RS14235	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CTV95_RS14240	COG0859	PFAM glycosyl transferase family 9
CTV95_RS14245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CTV95_RS14255	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CTV95_RS14260	COG2003	Belongs to the UPF0758 family
CTV95_RS14265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTV95_RS14270	COG0756	dUTP diphosphatase activity
CTV95_RS14275	COG1309	transcriptional regulator
CTV95_RS14280	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CTV95_RS14285	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CTV95_RS14290	COG4948	Mandelate Racemase Muconate Lactonizing
CTV95_RS14295	COG4172	Belongs to the ABC transporter superfamily
CTV95_RS14300	COG0747	negative chemotaxis
CTV95_RS14305	COG0601	transmembrane transport
CTV95_RS14310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTV95_RS14325	COG1446	asparaginase
CTV95_RS14330	COG0583	DNA-binding transcription factor activity
CTV95_RS14335	COG1561	YicC-like family, N-terminal region
CTV95_RS14340	COG0582	viral genome integration into host DNA
CTV95_RS14350	COG2856	Zn peptidase
CTV95_RS14405	COG3423	Transcriptional regulator
CTV95_RS14435	COG0628	permease
CTV95_RS14440	COG1304	FMN binding
CTV95_RS14445	COG1012	belongs to the aldehyde dehydrogenase family
CTV95_RS14455	COG3239	Fatty acid desaturase
CTV95_RS14485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTV95_RS14490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CTV95_RS14495	COG3136	membrane protein required for alginate biosynthesis
CTV95_RS14510	COG4677	pectinesterase activity
CTV95_RS14515	COG2771	luxR family
CTV95_RS14525	COG0137	argininosuccinate synthase activity
CTV95_RS14535	COG2207	Transcriptional regulator
CTV95_RS14535	COG1609	Transcriptional regulator
CTV95_RS14540	COG4214	carbohydrate transport
CTV95_RS14545	COG1129	ABC transporter
CTV95_RS14550	COG4213	ABC transporter substrate-binding protein
CTV95_RS14555	COG2115	Belongs to the xylose isomerase family
CTV95_RS14560	COG1070	Carbohydrate kinase
CTV95_RS14565	COG3274	enterobacterial common antigen metabolic process
CTV95_RS14570	COG1012	belongs to the aldehyde dehydrogenase family
CTV95_RS14575	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CTV95_RS14580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CTV95_RS14585	COG0840	transmembrane signaling receptor activity
CTV95_RS14595	COG3722	fumarate hydratase activity
CTV95_RS14600	COG0246	Mannitol dehydrogenase
CTV95_RS14605	COG2213	PTS system mannitol-specific
CTV95_RS14605	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTV95_RS14615	COG0751	glycine-tRNA ligase activity
CTV95_RS14620	COG0752	glycyl-tRNA synthetase alpha subunit
CTV95_RS14625	COG0730	response to heat
CTV95_RS14630	COG2818	Glycosylase
CTV95_RS14635	COG0456	acetyltransferase
CTV95_RS14640	COG0840	transmembrane signaling receptor activity
CTV95_RS14645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CTV95_RS14660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTV95_RS14665	COG4172	Belongs to the ABC transporter superfamily
CTV95_RS14670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTV95_RS14680	COG3479	Phenolic acid decarboxylase
CTV95_RS14690	COG1280	lysine exporter protein (LysE YggA)
CTV95_RS14695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTV95_RS14715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTV95_RS14720	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CTV95_RS14740	COG2214	Heat shock protein DnaJ domain protein
CTV95_RS14745	COG0443	Heat shock 70 kDa protein
CTV95_RS14760	COG3712	iron ion homeostasis
CTV95_RS14765	COG1595	DNA-templated transcription, initiation
CTV95_RS14770	COG1629	transport
CTV95_RS14780	COG0742	ribosomal rna small subunit methyltransferase
CTV95_RS14785	COG0737	Belongs to the 5'-nucleotidase family
CTV95_RS14795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTV95_RS14800	COG0589	response to stress
CTV95_RS14810	COG0306	phosphate transporter
CTV95_RS14815	COG2081	HI0933 family
CTV95_RS14820	COG2200	EAL domain
CTV95_RS14835	COG2194	sulfuric ester hydrolase activity
CTV95_RS14840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CTV95_RS14845	COG0194	GDP metabolic process
CTV95_RS14850	COG1758	RNA polymerase activity
CTV95_RS14855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTV95_RS14860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTV95_RS14865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CTV95_RS14870	COG2233	PERMEase
CTV95_RS14875	COG2982	Protein involved in outer membrane biogenesis
CTV95_RS14880	COG0456	acetyltransferase
CTV95_RS14885	COG1490	D-aminoacyl-tRNA deacylase activity
CTV95_RS14890	COG1011	Hydrolase
CTV95_RS14910	COG3852	Histidine kinase
CTV95_RS14920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTV95_RS14925	COG3078	GTPase activator activity
CTV95_RS14935	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CTV95_RS14940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTV95_RS14940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTV95_RS14950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CTV95_RS14955	COG3084	Protein conserved in bacteria
CTV95_RS14960	COG0746	molybdenum cofactor guanylyltransferase activity
CTV95_RS14965	COG1763	Mo-molybdopterin cofactor biosynthetic process
CTV95_RS14990	COG1609	Transcriptional regulator
CTV95_RS14995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTV95_RS15005	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTV95_RS15010	COG1129	ABC transporter
CTV95_RS15015	COG1869	D-ribose catabolic process
CTV95_RS15020	COG3111	PFAM Bacterial OB fold (BOF) protein
CTV95_RS15030	COG0642	Histidine kinase
CTV95_RS15035	COG3158	transport of potassium into the cell
CTV95_RS15040	COG0714	Associated with various cellular activities
CTV95_RS15045	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CTV95_RS15050	COG2502	aspartate--ammonia ligase
CTV95_RS15055	COG1522	sequence-specific DNA binding
CTV95_RS15060	COG0716	FMN binding
CTV95_RS15065	COG0445	tRNA wobble uridine modification
CTV95_RS15070	COG0357	Ribosomal RNA small subunit methyltransferase G
CTV95_RS15075	COG3312	ion transport
CTV95_RS15080	COG0356	it plays a direct role in the translocation of protons across the membrane
CTV95_RS15090	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CTV95_RS15095	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CTV95_RS15100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CTV95_RS15105	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CTV95_RS15110	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CTV95_RS15115	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CTV95_RS15125	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CTV95_RS15130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTV95_RS15140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CTV95_RS15145	COG0573	inorganic phosphate transmembrane transporter activity
CTV95_RS15150	COG0581	inorganic phosphate transmembrane transporter activity
CTV95_RS15155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CTV95_RS15165	COG1396	sequence-specific DNA binding
CTV95_RS15170	COG3135	benzoate transporter
CTV95_RS15185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTV95_RS15190	COG0765	amino acid transport
CTV95_RS15195	COG0765	amino acid transport
CTV95_RS15200	COG3547	Transposase (IS116 IS110 IS902 family)
CTV95_RS15205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTV95_RS15210	COG2252	PERMEase
CTV95_RS15215	COG2091	lysine biosynthetic process via aminoadipic acid
CTV95_RS15220	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTV95_RS15225	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTV95_RS15225	COG0493	'glutamate synthase
CTV95_RS15260	COG0457	Tetratricopeptide repeat
CTV95_RS15265	COG1649	PFAM Uncharacterised BCR, COG1649
CTV95_RS15265	COG0726	polysaccharide deacetylase
CTV95_RS15270	COG1215	transferase activity, transferring glycosyl groups
CTV95_RS15280	COG1733	regulation of RNA biosynthetic process
CTV95_RS15285	COG0702	epimerase
CTV95_RS15295	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CTV95_RS15300	COG0706	membrane insertase activity
CTV95_RS15310	COG0594	ribonuclease P activity
CTV95_RS15315	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CTV95_RS15320	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CTV95_RS15325	COG0592	DNA-directed DNA polymerase activity
CTV95_RS15330	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CTV95_RS15350	COG0840	transmembrane signaling receptor activity
CTV95_RS15355	COG1609	Transcriptional regulator
CTV95_RS15360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTV95_RS15365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTV95_RS15370	COG1447	Phosphotransferase system cellobiose-specific component IIA
CTV95_RS15375	COG2723	6-phospho-beta-galactosidase activity
CTV95_RS15380	COG0561	phosphatase activity
CTV95_RS15390	COG0747	negative chemotaxis
CTV95_RS15395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTV95_RS15410	COG0601	transmembrane transport
CTV95_RS15415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTV95_RS15425	COG2186	Transcriptional regulator
CTV95_RS15430	COG3734	2-keto-3-deoxy-galactonokinase
CTV95_RS15435	COG0800	Aldolase
CTV95_RS15440	COG4948	Mandelate Racemase Muconate Lactonizing
CTV95_RS15445	COG2271	Major facilitator Superfamily
CTV95_RS15455	COG1116	anion transmembrane transporter activity
CTV95_RS15460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTV95_RS15465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTV95_RS15470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTV95_RS15485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTV95_RS15485	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTV95_RS15490	COG2723	6-phospho-beta-galactosidase activity
CTV95_RS15500	COG0823	Involved in the tonB-independent uptake of proteins
CTV95_RS15505	COG5645	(Lipo)protein
CTV95_RS15510	COG0071	Belongs to the small heat shock protein (HSP20) family
CTV95_RS15515	COG0071	Belongs to the small heat shock protein (HSP20) family
CTV95_RS15520	COG2985	domain, Protein
CTV95_RS15520	COG0569	domain protein
CTV95_RS15525	COG0471	metal ion transport
CTV95_RS15530	COG3290	protein histidine kinase activity
CTV95_RS15535	COG4565	transcriptional regulatory protein
CTV95_RS15585	COG3493	citrate carrier protein
CTV95_RS15595	COG0747	negative chemotaxis
CTV95_RS15600	COG0601	transmembrane transport
CTV95_RS15605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTV95_RS15610	COG0444	Belongs to the ABC transporter superfamily
CTV95_RS15615	COG4608	Belongs to the ABC transporter superfamily
CTV95_RS15645	COG4104	PAAR repeat-containing protein
CTV95_RS15645	COG3209	COG3209 Rhs family protein
CTV95_RS15660	COG4104	PAAR repeat-containing protein
CTV95_RS15660	COG3209	COG3209 Rhs family protein
CTV95_RS15670	COG3501	Rhs element vgr protein
CTV95_RS15680	COG3977	Valine--pyruvate aminotransferase
CTV95_RS15700	COG0028	Belongs to the TPP enzyme family
CTV95_RS15710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CTV95_RS15715	COG3118	belongs to the thioredoxin family
CTV95_RS15715	COG0457	Tetratricopeptide repeat
CTV95_RS15720	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CTV95_RS15730	COG1215	transferase activity, transferring glycosyl groups
CTV95_RS15735	COG1192	Involved in chromosome partitioning
CTV95_RS15755	COG2194	sulfuric ester hydrolase activity
CTV95_RS15760	COG2200	EAL domain
CTV95_RS15760	COG2199	diguanylate cyclase activity
CTV95_RS15765	COG1301	dicarboxylic acid transport
CTV95_RS15770	COG0612	Peptidase, M16
CTV95_RS15775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTV95_RS15780	COG1295	ribonuclease BN
CTV95_RS15785	COG0477	Major facilitator Superfamily
CTV95_RS15795	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CTV95_RS15800	COG0425	Belongs to the sulfur carrier protein TusA family
CTV95_RS15810	COG3714	YhhN family
CTV95_RS15820	COG3776	membrane
CTV95_RS15825	COG0742	ribosomal rna small subunit methyltransferase
CTV95_RS15830	COG0552	protein localization to endoplasmic reticulum
CTV95_RS15835	COG2884	Cell division ATP-binding protein ftsE
CTV95_RS15840	COG2177	Part of the ABC transporter FtsEX involved in
CTV95_RS15855	COG0683	leucine binding
CTV95_RS15860	COG0559	Belongs to the binding-protein-dependent transport system permease family
CTV95_RS15865	COG4177	L-phenylalanine transmembrane transporter activity
CTV95_RS15870	COG0411	ABC transporter
CTV95_RS15875	COG0410	ABC transporter
CTV95_RS15880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTV95_RS15885	COG0840	transmembrane signaling receptor activity
CTV95_RS15890	COG0840	transmembrane signaling receptor activity
CTV95_RS15895	COG0840	transmembrane signaling receptor activity
CTV95_RS15900	COG0840	transmembrane signaling receptor activity
CTV95_RS15905	COG2610	gluconate transmembrane transporter activity
CTV95_RS15910	COG3622	Belongs to the hyi family
CTV95_RS15915	COG0235	Class ii aldolase
CTV95_RS15920	COG3395	kinase activity
CTV95_RS15925	COG2084	Dehydrogenase
CTV95_RS15930	COG1349	DNA-binding transcription factor activity
CTV95_RS15950	COG3609	addiction module antidote protein, CC2985 family
CTV95_RS15955	COG1653	transport
CTV95_RS15960	COG1175	transmembrane transport
CTV95_RS15965	COG0395	ABC-type sugar transport system, permease component
CTV95_RS15970	COG3842	ATPase activity
CTV95_RS15975	COG0584	glycerophosphoryl diester phosphodiesterase
CTV95_RS15990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CTV95_RS16005	COG2205	protein histidine kinase activity
CTV95_RS16010	COG0745	RESPONSE REGULATOR receiver
CTV95_RS16015	COG3678	ATP-independent chaperone mediated protein folding
CTV95_RS16030	COG2814	Major facilitator Superfamily
CTV95_RS16035	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CTV95_RS16040	COG0205	6-phosphofructokinase activity
CTV95_RS16045	COG0583	DNA-binding transcription factor activity
CTV95_RS16085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTV95_RS16090	COG1116	anion transmembrane transporter activity
CTV95_RS16095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTV95_RS16100	COG2957	Belongs to the agmatine deiminase family
CTV95_RS16105	COG0149	triose-phosphate isomerase activity
CTV95_RS16115	COG3152	Membrane
CTV95_RS16125	COG1494	fructose-1,6-bisphosphatase
CTV95_RS16135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CTV95_RS16145	COG3074	FtsZ-dependent cytokinesis
CTV95_RS16150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTV95_RS16155	COG1575	Belongs to the MenA family. Type 1 subfamily
CTV95_RS16160	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CTV95_RS16165	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CTV95_RS16170	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CTV95_RS16175	COG1609	Transcriptional regulator
CTV95_RS16180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTV95_RS16185	COG0254	rRNA binding
CTV95_RS16190	COG1598	PFAM Uncharacterised protein family UPF0150
CTV95_RS16195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTV95_RS16205	COG1120	ATPase activity
CTV95_RS16210	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
CTV95_RS16215	COG0626	cystathionine gamma-synthase activity
CTV95_RS16220	COG0460	homoserine dehydrogenase
CTV95_RS16220	COG0527	aspartate kinase activity
CTV95_RS16225	COG3842	ATPase activity
CTV95_RS16240	COG0395	ABC-type sugar transport system, permease component
CTV95_RS16245	COG1609	Transcriptional regulator
CTV95_RS16250	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTV95_RS16265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTV95_RS16270	COG1309	transcriptional regulator
CTV95_RS16280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CTV95_RS16285	COG4206	TonB-dependent receptor
CTV95_RS16290	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTV95_RS16330	COG1879	ABC-type sugar transport system periplasmic component
CTV95_RS16335	COG1129	ABC transporter
CTV95_RS16340	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTV95_RS16345	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTV95_RS16350	COG0583	DNA-binding transcription factor activity
CTV95_RS16355	COG3085	chromosome segregation
CTV95_RS16375	COG3978	acetolactate synthase activity
CTV95_RS16385	COG0129	dihydroxy-acid dehydratase activity
CTV95_RS16425	COG0583	DNA-binding transcription factor activity
CTV95_RS16430	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CTV95_RS16440	COG0583	DNA-binding transcription factor activity
CTV95_RS16450	COG0506	proline dehydrogenase activity
CTV95_RS16450	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTV95_RS16450	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTV95_RS16455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTV95_RS16460	COG0210	DNA helicase
CTV95_RS16465	COG0248	Ppx GppA phosphatase
CTV95_RS16470	COG0513	Belongs to the DEAD box helicase family
CTV95_RS16475	COG3118	belongs to the thioredoxin family
CTV95_RS16480	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CTV95_RS16485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CTV95_RS16490	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CTV95_RS16495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CTV95_RS16500	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CTV95_RS16505	COG1088	dTDP-glucose 4,6-dehydratase activity
CTV95_RS16510	COG0456	acetyltransferase
CTV95_RS16515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CTV95_RS16520	COG2244	polysaccharide biosynthetic process
CTV95_RS16525	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTV95_RS16535	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CTV95_RS16570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CTV95_RS16575	COG0456	acetyltransferase
CTV95_RS16580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTV95_RS16585	COG0765	amino acid transport
CTV95_RS16590	COG1126	abc transporter atp-binding protein
CTV95_RS16595	COG1473	amidohydrolase
CTV95_RS16600	COG1126	abc transporter atp-binding protein
CTV95_RS16605	COG0765	amino acid transport
CTV95_RS16610	COG4597	amino acid ABC transporter
CTV95_RS16615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTV95_RS16635	COG1802	Transcriptional regulator
CTV95_RS16640	COG3071	HemY protein
CTV95_RS16645	COG2959	enzyme of heme biosynthesis
CTV95_RS16655	COG0181	hydroxymethylbilane synthase activity
CTV95_RS16665	COG2814	Major facilitator Superfamily
CTV95_RS16670	COG1965	Belongs to the frataxin family
CTV95_RS16680	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CTV95_RS16695	COG1011	Hydrolase
CTV95_RS16700	COG0210	DNA helicase
CTV95_RS16705	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CTV95_RS16710	COG0598	Magnesium transport protein CorA
CTV95_RS16715	COG3180	Ammonia monooxygenase
CTV95_RS16725	COG2050	protein possibly involved in aromatic compounds catabolism
CTV95_RS16735	COG0514	ATP-dependent DNA helicase (RecQ)
CTV95_RS16740	COG1280	lysine exporter protein (LysE YggA)
CTV95_RS16745	COG1280	lysine exporter protein (LysE YggA)
CTV95_RS16750	COG2267	carboxylic ester hydrolase activity
CTV95_RS16755	COG0561	phosphatase activity
CTV95_RS16760	COG0584	glycerophosphoryl diester phosphodiesterase
CTV95_RS16765	COG2271	Major facilitator Superfamily
CTV95_RS16770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CTV95_RS16775	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CTV95_RS16780	COG0247	lactate metabolic process
CTV95_RS16790	COG1741	Belongs to the pirin family
CTV95_RS16795	COG1609	Transcriptional regulator
CTV95_RS16800	COG3265	gluconokinase activity
CTV95_RS16805	COG2610	gluconate transmembrane transporter activity
CTV95_RS16815	COG2095	MarC family integral membrane protein
CTV95_RS16820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CTV95_RS16830	COG3275	phosphorelay sensor kinase activity
CTV95_RS16835	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CTV95_RS16840	COG1523	belongs to the glycosyl hydrolase 13 family
CTV95_RS16845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CTV95_RS16850	COG0297	glycogen (starch) synthase activity
CTV95_RS16855	COG0058	SHG alpha-glucan phosphorylase activity
CTV95_RS16880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CTV95_RS16885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CTV95_RS16890	COG0705	Rhomboid family
CTV95_RS16895	COG1349	DNA-binding transcription factor activity
CTV95_RS16900	COG0058	SHG alpha-glucan phosphorylase activity
CTV95_RS16905	COG1640	4-alpha-glucanotransferase
CTV95_RS16910	COG0316	Belongs to the HesB IscA family
CTV95_RS16910	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CTV95_RS16915	COG1040	competence protein
CTV95_RS16920	COG2267	carboxylic ester hydrolase activity
CTV95_RS16925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTV95_RS16930	COG3157	Type VI secretion system effector, Hcp
CTV95_RS16960	COG1785	Belongs to the alkaline phosphatase family
CTV95_RS16980	COG0515	serine threonine protein kinase
CTV95_RS16980	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CTV95_RS17005	COG1414	Transcriptional regulator
CTV95_RS17010	COG2183	response to ionizing radiation
CTV95_RS17020	COG0840	transmembrane signaling receptor activity
CTV95_RS17030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTV95_RS17040	COG4264	IucA IucC family
CTV95_RS17045	COG4774	siderophore transport
CTV95_RS17050	COG0019	diaminopimelate decarboxylase activity
CTV95_RS17055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTV95_RS17060	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CTV95_RS17065	COG2814	Major facilitator Superfamily
CTV95_RS17090	COG3547	Transposase (IS116 IS110 IS902 family)
CTV95_RS17095	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CTV95_RS17100	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CTV95_RS17105	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTV95_RS17110	COG1011	Hydrolase
CTV95_RS17125	COG0494	nUDIX hydrolase
CTV95_RS17135	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CTV95_RS17160	COG4796	Type ii and iii secretion system protein
CTV95_RS17170	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CTV95_RS17175	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CTV95_RS17190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTV95_RS17195	COG0546	phosphoglycolate phosphatase activity
CTV95_RS17205	COG1473	amidohydrolase
CTV95_RS17230	COG1648	precorrin-2 dehydrogenase activity
CTV95_RS17230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTV95_RS17240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTV95_RS17250	COG4948	Mandelate Racemase Muconate Lactonizing
CTV95_RS17255	COG0747	negative chemotaxis
CTV95_RS17260	COG0601	transmembrane transport
CTV95_RS17265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTV95_RS17270	COG0444	Belongs to the ABC transporter superfamily
CTV95_RS17275	COG4608	Belongs to the ABC transporter superfamily
CTV95_RS17280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTV95_RS17300	COG3866	Pectate lyase
CTV95_RS17350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTV95_RS17355	COG1765	OsmC-like protein
CTV95_RS17360	COG3954	Phosphoribulokinase
CTV95_RS17365	COG3089	Belongs to the UPF0270 family
CTV95_RS17370	COG0429	hydrolase of the alpha beta-hydrolase fold
CTV95_RS17385	COG3853	Toxic anion resistance protein (TelA)
CTV95_RS17390	COG0488	(ABC) transporter
CTV95_RS17395	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTV95_RS17400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTV95_RS17400	COG0475	glutathione-regulated potassium exporter activity
CTV95_RS17405	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CTV95_RS17410	COG1047	Peptidyl-prolyl cis-trans
CTV95_RS17415	COG2900	Belongs to the SlyX family
CTV95_RS17420	COG0545	Peptidyl-prolyl cis-trans isomerase
CTV95_RS17435	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CTV95_RS17440	COG0642	Histidine kinase
CTV95_RS17445	COG0745	RESPONSE REGULATOR receiver
CTV95_RS17455	COG2964	Protein conserved in bacteria
CTV95_RS17460	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CTV95_RS17465	COG2923	Belongs to the DsrF TusC family
CTV95_RS17470	COG2168	tRNA wobble position uridine thiolation
CTV95_RS17475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CTV95_RS17480	COG0049	tRNA binding
CTV95_RS17485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CTV95_RS17500	COG2193	ferroxidase activity
CTV95_RS17505	COG0051	transcription antitermination factor activity, RNA binding
CTV95_RS17510	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CTV95_RS17515	COG0088	Forms part of the polypeptide exit tunnel
CTV95_RS17525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CTV95_RS17530	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CTV95_RS17535	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CTV95_RS17540	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CTV95_RS17545	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CTV95_RS17550	COG0255	Belongs to the universal ribosomal protein uL29 family
CTV95_RS17555	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CTV95_RS17565	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CTV95_RS17570	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CTV95_RS17575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CTV95_RS17580	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CTV95_RS17585	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CTV95_RS17590	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CTV95_RS17595	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CTV95_RS17600	COG1841	ribosomal large subunit assembly
CTV95_RS17605	COG0200	Binds to the 23S rRNA
CTV95_RS17610	COG0201	protein transport
CTV95_RS17615	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CTV95_RS17620	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CTV95_RS17630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CTV95_RS17635	COG0202	RNA polymerase activity
CTV95_RS17640	COG0203	ribosomal protein L17
CTV95_RS17645	COG3036	rescue of stalled ribosome
CTV95_RS17650	COG1970	mechanosensitive ion channel activity
CTV95_RS17655	COG0569	domain protein
CTV95_RS17660	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CTV95_RS17660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CTV95_RS17665	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CTV95_RS17670	COG0242	peptide deformylase activity
CTV95_RS17675	COG0758	DNA mediated transformation
CTV95_RS17680	COG2922	Belongs to the Smg family
CTV95_RS17685	COG0551	DNA topoisomerase type I activity
CTV95_RS17690	COG0009	L-threonylcarbamoyladenylate synthase
CTV95_RS17695	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CTV95_RS17705	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTV95_RS17735	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CTV95_RS17740	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CTV95_RS17750	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CTV95_RS17755	COG3547	Transposase (IS116 IS110 IS902 family)
CTV95_RS17765	COG1410	methionine synthase
CTV95_RS17765	COG0646	methionine synthase
CTV95_RS17780	COG2207	Transcriptional regulator
CTV95_RS17790	COG0471	metal ion transport
CTV95_RS17800	COG0527	aspartate kinase activity
CTV95_RS17805	COG0166	Belongs to the GPI family
CTV95_RS17815	COG1509	lysine 2,3-aminomutase activity
CTV95_RS17820	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CTV95_RS17840	COG3040	lipid binding
CTV95_RS17845	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CTV95_RS17850	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CTV95_RS17855	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTV95_RS17860	COG1053	succinate dehydrogenase
CTV95_RS17865	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CTV95_RS17870	COG1511	domain protein
CTV95_RS17870	COG3264	Mechanosensitive ion channel
CTV95_RS17875	COG0688	phosphatidylethanolamine metabolic process
CTV95_RS17880	COG1162	GTPase activity
CTV95_RS17885	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CTV95_RS17925	COG1011	Hydrolase
CTV95_RS17935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTV95_RS17940	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CTV95_RS17960	COG1064	alcohol dehydrogenase
CTV95_RS17965	COG1704	LemA family
CTV95_RS17980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTV95_RS18000	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CTV95_RS18015	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CTV95_RS18020	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CTV95_RS18020	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CTV95_RS18025	COG0802	atpase or kinase
CTV95_RS18035	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CTV95_RS18040	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CTV95_RS18045	COG1923	regulation of RNA biosynthetic process
CTV95_RS18050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTV95_RS18055	COG0330	HflC and HflK could
CTV95_RS18060	COG0330	HflC and HflK could
CTV95_RS18065	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CTV95_RS18070	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CTV95_RS18075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTV95_RS18080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CTV95_RS18085	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CTV95_RS18090	COG1678	Uncharacterized ACR, COG1678
CTV95_RS18095	COG0189	ligase activity
CTV95_RS18100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTV95_RS18105	COG2356	endonuclease I
CTV95_RS18110	COG3091	SprT-like family
CTV95_RS18115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CTV95_RS18120	COG1166	arginine decarboxylase activity
CTV95_RS18130	COG0501	Belongs to the peptidase M48B family
CTV95_RS18135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTV95_RS18140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CTV95_RS18145	COG0126	phosphoglycerate kinase activity
CTV95_RS18150	COG0191	fructose-bisphosphate aldolase activity
CTV95_RS18155	COG0668	transmembrane transport
CTV95_RS18160	COG1279	arginine transmembrane transporter activity
CTV95_RS18170	COG0583	DNA-binding transcription factor activity
CTV95_RS18175	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CTV95_RS18180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTV95_RS18185	COG0604	alcohol dehydrogenase
CTV95_RS18190	COG0583	DNA-binding transcription factor activity
CTV95_RS18195	COG0840	transmembrane signaling receptor activity
CTV95_RS18200	COG0488	(ABC) transporter
CTV95_RS18210	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CTV95_RS18215	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CTV95_RS18225	COG2207	Transcriptional regulator
CTV95_RS18225	COG3708	Transcriptional regulator
CTV95_RS18230	COG3045	CreA protein
CTV95_RS18235	COG0745	RESPONSE REGULATOR receiver
CTV95_RS18240	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CTV95_RS18255	COG0083	homoserine kinase activity
CTV95_RS18265	COG3022	response to hydroperoxide
CTV95_RS18270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTV95_RS18280	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTV95_RS18290	COG1584	GPR1 FUN34 yaaH family protein
CTV95_RS18295	COG0443	Heat shock 70 kDa protein
CTV95_RS18300	COG0484	heat shock protein binding
CTV95_RS18305	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CTV95_RS18310	COG0583	DNA-binding transcription factor activity
CTV95_RS18315	COG0268	Binds directly to 16S ribosomal RNA
CTV95_RS18320	COG0196	riboflavin kinase activity
CTV95_RS18325	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CTV95_RS18335	COG1047	Peptidyl-prolyl cis-trans
CTV95_RS18340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CTV95_RS18345	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CTV95_RS18350	COG0505	Belongs to the CarA family
CTV95_RS18355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CTV95_RS18365	COG2966	Psort location CytoplasmicMembrane, score
CTV95_RS18370	COG3610	response to peptide
CTV95_RS18375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CTV95_RS18395	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CTV95_RS18400	COG2967	ApaG domain
CTV95_RS18405	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CTV95_RS18410	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CTV95_RS18415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTV95_RS18420	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CTV95_RS18425	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CTV95_RS18430	COG0564	pseudouridine synthase activity
CTV95_RS18435	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CTV95_RS18440	COG0417	DNA replication proofreading
CTV95_RS18445	COG3706	GGDEF domain
CTV95_RS18450	COG0586	Pfam SNARE associated Golgi protein
CTV95_RS18455	COG0440	acetolactate synthase activity
CTV95_RS18460	COG0028	Belongs to the TPP enzyme family
CTV95_RS18475	COG3507	Belongs to the glycosyl hydrolase 43 family
CTV95_RS18480	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CTV95_RS18485	COG1178	ABC-type Fe3 transport system permease component
CTV95_RS18490	COG4143	(ABC) transporter
CTV95_RS18495	COG4533	DNA binding
CTV95_RS18515	COG3033	Beta-eliminating lyase
CTV95_RS18525	COG0840	transmembrane signaling receptor activity
CTV95_RS18545	COG0066	3-isopropylmalate dehydratase activity
CTV95_RS18550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CTV95_RS18555	COG0473	3-isopropylmalate dehydrogenase activity
CTV95_RS18560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTV95_RS18565	COG1022	Amp-dependent synthetase and ligase
CTV95_RS18570	COG0028	Belongs to the TPP enzyme family
CTV95_RS18590	COG2001	Belongs to the MraZ family
CTV95_RS18595	COG0275	rRNA processing
CTV95_RS18600	COG3116	cell division
CTV95_RS18605	COG0768	penicillin binding
CTV95_RS18610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CTV95_RS18615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTV95_RS18620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CTV95_RS18625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CTV95_RS18630	COG0772	Belongs to the SEDS family
CTV95_RS18635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CTV95_RS18640	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTV95_RS18645	COG1181	Belongs to the D-alanine--D-alanine ligase family
CTV95_RS18650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CTV95_RS18655	COG0849	cell division
CTV95_RS18660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CTV95_RS18665	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CTV95_RS18680	COG0653	protein targeting
CTV95_RS18685	COG0494	nUDIX hydrolase
CTV95_RS18690	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CTV95_RS18695	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CTV95_RS18700	COG0237	dephospho-CoA kinase activity
CTV95_RS18705	COG0516	GMP reductase activity
CTV95_RS18710	COG1459	type II secretion system
CTV95_RS18715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CTV95_RS18720	COG4969	Belongs to the N-Me-Phe pilin family
CTV95_RS18725	COG0157	Belongs to the NadC ModD family
CTV95_RS18730	COG3248	Nucleoside-binding outer membrane protein
CTV95_RS18735	COG3023	N-Acetylmuramoyl-L-alanine amidase
CTV95_RS18740	COG3725	Membrane protein required for beta-lactamase induction
CTV95_RS18745	COG3940	Belongs to the glycosyl hydrolase 43 family
CTV95_RS18750	COG2211	Major facilitator Superfamily
CTV95_RS18755	COG1113	amino acid transport
CTV95_RS18765	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CTV95_RS18770	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTV95_RS18775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTV95_RS18780	COG0583	DNA-binding transcription factor activity
CTV95_RS18790	COG2814	Major facilitator Superfamily
CTV95_RS18800	COG1073	alpha beta
CTV95_RS18810	COG2079	MmgE PrpD family protein
CTV95_RS18815	COG2207	Transcriptional regulator
CTV95_RS18825	COG0640	Transcriptional regulator
CTV95_RS18840	COG3112	Uncharacterised protein family (UPF0231)
CTV95_RS18845	COG0765	amino acid transport
CTV95_RS18855	COG0765	amino acid transport
CTV95_RS18860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTV95_RS18865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTV95_RS18880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTV95_RS18885	COG1609	Transcriptional regulator
CTV95_RS18905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CTV95_RS18910	COG1882	Formate acetyltransferase
CTV95_RS18915	COG1028	Short-chain dehydrogenase reductase Sdr
CTV95_RS18920	COG2731	YhcH YjgK YiaL family protein
CTV95_RS18935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTV95_RS18940	COG1454	alcohol dehydrogenase
CTV95_RS18945	COG3395	kinase activity
CTV95_RS18950	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CTV95_RS18955	COG1349	DNA-binding transcription factor activity
CTV95_RS18965	COG0803	Belongs to the bacterial solute-binding protein 9 family
CTV95_RS18970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTV95_RS18975	COG1121	(ABC) transporter
CTV95_RS18985	COG2971	BadF BadG BcrA BcrD
CTV95_RS19005	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CTV95_RS19010	COG3842	ATPase activity
CTV95_RS19015	COG1175	transmembrane transport
CTV95_RS19020	COG0395	ABC-type sugar transport system, permease component
CTV95_RS19040	COG0629	single-stranded DNA binding
CTV95_RS19050	COG0432	Pfam Uncharacterised protein family UPF0047
CTV95_RS19075	COG1203	CRISPR-associated helicase, Cas3
CTV95_RS19080	COG1518	maintenance of DNA repeat elements
CTV95_RS19115	COG1451	nucleotide metabolic process
CTV95_RS19120	COG1448	Aminotransferase
CTV95_RS19130	COG1522	sequence-specific DNA binding
CTV95_RS19150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CTV95_RS19165	COG2124	cytochrome p450
CTV95_RS19175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTV95_RS19195	COG0583	DNA-binding transcription factor activity
CTV95_RS19200	COG0583	DNA-binding transcription factor activity
CTV95_RS19215	COG1396	sequence-specific DNA binding
CTV95_RS19220	COG1609	Transcriptional regulator
CTV95_RS19225	COG1447	Phosphotransferase system cellobiose-specific component IIA
CTV95_RS19230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTV95_RS19235	COG2723	6-phospho-beta-galactosidase activity
CTV95_RS19240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTV95_RS19245	COG2186	Transcriptional regulator
CTV95_RS19255	COG0204	Acyl-transferase
CTV95_RS19255	COG0318	PFAM AMP-dependent synthetase and ligase
CTV95_RS19260	COG0477	Major facilitator Superfamily
CTV95_RS19265	COG2153	protein acetylation
CTV95_RS19285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTV95_RS19290	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CTV95_RS19295	COG1872	DUF167
CTV95_RS19300	COG0762	integral membrane protein
CTV95_RS19305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CTV95_RS19310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CTV95_RS19315	COG2805	Type II/IV secretion system protein
CTV95_RS19325	COG0840	transmembrane signaling receptor activity
CTV95_RS19330	COG1959	2 iron, 2 sulfur cluster binding
CTV95_RS19335	COG0557	exoribonuclease II activity
CTV95_RS19340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTV95_RS19345	COG0840	transmembrane signaling receptor activity
CTV95_RS19350	COG3766	membrane
CTV95_RS19365	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CTV95_RS19370	COG1690	Belongs to the RtcB family
CTV95_RS19375	COG0840	transmembrane signaling receptor activity
CTV95_RS19380	COG1073	alpha beta
CTV95_RS19390	COG0360	Binds together with S18 to 16S ribosomal RNA
CTV95_RS19395	COG2965	DNA replication, synthesis of RNA primer
CTV95_RS19400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CTV95_RS19405	COG0359	binds to the 23S rRNA
CTV95_RS19415	COG3061	Opacity-associated protein A
CTV95_RS19420	COG0545	Peptidyl-prolyl cis-trans isomerase
CTV95_RS19425	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CTV95_RS19430	COG3961	Belongs to the TPP enzyme family
CTV95_RS19445	COG1733	regulation of RNA biosynthetic process
CTV95_RS19450	COG0737	Belongs to the 5'-nucleotidase family
CTV95_RS19455	COG1218	3'(2'),5'-bisphosphate nucleotidase
CTV95_RS19460	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CTV95_RS19470	COG1253	flavin adenine dinucleotide binding
CTV95_RS19475	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CTV95_RS19485	COG0729	surface antigen
CTV95_RS19490	COG2911	Protein conserved in bacteria
CTV95_RS19495	COG2105	PFAM AIG2 family protein
CTV95_RS19500	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CTV95_RS19505	COG0840	transmembrane signaling receptor activity
CTV95_RS19510	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CTV95_RS19515	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CTV95_RS19520	COG1968	undecaprenyl-diphosphatase activity
CTV95_RS19525	COG0617	tRNA 3'-terminal CCA addition
CTV95_RS19530	COG4991	sh3 domain protein
CTV95_RS19535	COG3025	triphosphatase activity
CTV95_RS19540	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CTV95_RS19545	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CTV95_RS19545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CTV95_RS19550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CTV95_RS19555	COG3530	Putative quorum-sensing-regulated virulence factor
CTV95_RS19570	COG0840	transmembrane signaling receptor activity
CTV95_RS19580	COG2721	sulfolactate sulfo-lyase activity
CTV95_RS19585	COG2271	Major facilitator Superfamily
CTV95_RS19590	COG4948	Mandelate Racemase Muconate Lactonizing
CTV95_RS19595	COG4948	Mandelate Racemase Muconate Lactonizing
CTV95_RS19605	COG2084	Dehydrogenase
CTV95_RS19610	COG1929	Belongs to the glycerate kinase type-1 family
CTV95_RS19620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CTV95_RS19625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTV95_RS19635	COG3956	TIGRFAM MazG family protein
CTV95_RS19640	COG0504	CTP synthase activity
CTV95_RS19645	COG0148	phosphopyruvate hydratase activity
CTV95_RS19665	COG0583	DNA-binding transcription factor activity
CTV95_RS19675	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CTV95_RS19680	COG1028	Short-chain dehydrogenase reductase Sdr
CTV95_RS19685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTV95_RS19690	COG0602	queuosine metabolic process
CTV95_RS19695	COG0720	synthase
CTV95_RS19715	COG2200	EAL domain
CTV95_RS19725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CTV95_RS19730	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTV95_RS19735	COG0175	sulfate reduction
CTV95_RS19745	COG0444	Belongs to the ABC transporter superfamily
CTV95_RS19760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTV95_RS19765	COG0584	glycerophosphoryl diester phosphodiesterase
CTV95_RS19770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTV95_RS19770	COG1648	precorrin-2 dehydrogenase activity
CTV95_RS19775	COG0175	sulfate reduction
CTV95_RS19780	COG2895	sulfate adenylyltransferase (ATP) activity
CTV95_RS19785	COG0529	Catalyzes the synthesis of activated sulfate
CTV95_RS19795	COG1126	abc transporter atp-binding protein
CTV95_RS19800	COG0765	amino acid transport
CTV95_RS19810	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CTV95_RS19815	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CTV95_RS19820	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CTV95_RS19825	COG0585	pseudouridine synthase activity
CTV95_RS19830	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTV95_RS19835	COG4942	peptidase
CTV95_RS19835	COG1388	LysM domain
CTV95_RS19845	COG0442	prolyl-tRNA aminoacylation
CTV95_RS19850	COG1720	tRNA m6t6A37 methyltransferase activity
CTV95_RS19860	COG1464	Belongs to the NlpA lipoprotein family
CTV95_RS19865	COG2011	ABC-type metal ion transport system permease component
CTV95_RS19870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTV95_RS19875	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CTV95_RS19915	COG0477	Major facilitator Superfamily
CTV95_RS19920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTV95_RS19925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTV95_RS19925	COG0045	succinate-CoA ligase (ADP-forming) activity
CTV95_RS19925	COG1042	CoA-binding domain protein
CTV95_RS19930	COG3148	PFAM DTW domain containing protein
CTV95_RS19935	COG3118	belongs to the thioredoxin family
CTV95_RS19940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTV95_RS19950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CTV95_RS19955	COG2814	Major facilitator Superfamily
CTV95_RS19960	COG1566	PFAM secretion protein HlyD family protein
CTV95_RS19965	COG1846	Transcriptional regulator
CTV95_RS19975	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTV95_RS19980	COG2814	Major facilitator Superfamily
CTV95_RS19985	COG2706	6-phosphogluconolactonase activity
CTV95_RS19990	COG2113	Glycine betaine
CTV95_RS19995	COG4176	ABC-type proline glycine betaine transport system permease component
CTV95_RS20000	COG4175	Glycine betaine
CTV95_RS20045	COG0765	amino acid transport
CTV95_RS20055	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CTV95_RS20070	COG0436	Aminotransferase
CTV95_RS20075	COG0235	Class ii aldolase
CTV95_RS20080	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CTV95_RS20085	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CTV95_RS20095	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CTV95_RS20100	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CTV95_RS20110	COG1960	acyl-CoA dehydrogenase activity
CTV95_RS20115	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CTV95_RS20120	COG0121	glutamine amidotransferase
CTV95_RS20125	COG3034	peptidoglycan biosynthetic process
CTV95_RS20130	COG2226	methyltransferase
CTV95_RS20140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTV95_RS20145	COG2195	Cleaves the N-terminal amino acid of tripeptides
CTV95_RS20150	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CTV95_RS20155	COG1073	alpha beta
CTV95_RS20170	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CTV95_RS20175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CTV95_RS20190	COG0582	viral genome integration into host DNA
CTV95_RS20205	COG4974	Belongs to the 'phage' integrase family
CTV95_RS20210	COG4974	Belongs to the 'phage' integrase family
CTV95_RS20250	COG1196	nuclear chromosome segregation
CTV95_RS20305	COG0582	viral genome integration into host DNA
CTV95_RS20320	COG3727	T/G mismatch-specific endonuclease activity
CTV95_RS20395	COG3829	transcription factor binding
CTV95_RS20430	COG3501	Rhs element vgr protein
CTV95_RS20455	COG3209	COG3209 Rhs family protein
CTV95_RS20475	COG3209	COG3209 Rhs family protein
CTV95_RS20495	COG2999	glutathione oxidoreductase activity
CTV95_RS20500	COG0583	DNA-binding transcription factor activity
CTV95_RS20505	COG2814	Major facilitator Superfamily
CTV95_RS20530	COG1546	Belongs to the CinA family
CTV95_RS20535	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CTV95_RS20540	COG2137	regulation of response to DNA damage stimulus
CTV95_RS20545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CTV95_RS20550	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CTV95_RS20575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTV95_RS20580	COG1238	metal cluster binding
CTV95_RS20585	COG2918	glutathione biosynthetic process
CTV95_RS20590	COG1854	S-ribosylhomocysteine lyase activity
CTV95_RS20595	COG4137	Cytochrome C assembly protein
CTV95_RS20600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTV95_RS20605	COG0228	four-way junction DNA binding
CTV95_RS20610	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CTV95_RS20615	COG0336	Belongs to the RNA methyltransferase TrmD family
CTV95_RS20620	COG0335	large ribosomal subunit rRNA binding
CTV95_RS20630	COG2264	protein methyltransferase activity
CTV95_RS20640	COG3279	Response regulator of the LytR AlgR family
CTV95_RS20645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTV95_RS20650	COG1605	Chorismate mutase
CTV95_RS20650	COG0287	Prephenate dehydrogenase
CTV95_RS20655	COG0077	Prephenate dehydratase
CTV95_RS20655	COG1605	Chorismate mutase
CTV95_RS20660	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CTV95_RS20665	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTV95_RS20675	COG0564	pseudouridine synthase activity
CTV95_RS20685	COG0542	response to heat
CTV95_RS20720	COG3021	interspecies interaction between organisms
CTV95_RS20725	COG1388	LysM domain
CTV95_RS20725	COG0741	lytic transglycosylase activity
CTV95_RS20730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTV95_RS20735	COG2226	methyltransferase
CTV95_RS20740	COG0328	RNA-DNA hybrid ribonuclease activity
CTV95_RS20755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTV95_RS20765	COG1780	Probably involved in ribonucleotide reductase function
CTV95_RS20770	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTV95_RS20775	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CTV95_RS20780	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CTV95_RS20790	COG1177	transmembrane transport
CTV95_RS20795	COG3842	ATPase activity
CTV95_RS20810	COG0288	reversible hydration of carbon dioxide
CTV95_RS20815	COG1131	(ABC) transporter
CTV95_RS20820	COG0842	Transport permease protein
CTV95_RS20825	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CTV95_RS20830	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CTV95_RS20835	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CTV95_RS20840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTV95_RS20850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTV95_RS20860	COG1489	DNA binding
CTV95_RS20865	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CTV95_RS20870	COG1643	Atp-dependent helicase
CTV95_RS20875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTV95_RS20880	COG1120	ATPase activity
CTV95_RS20885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTV95_RS20890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTV95_RS20900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTV95_RS20905	COG0625	glutathione transferase activity
CTV95_RS20910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CTV95_RS20915	COG0316	Belongs to the HesB IscA family
CTV95_RS20925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTV95_RS20930	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CTV95_RS20935	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CTV95_RS20940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTV95_RS20945	COG3835	regulator
CTV95_RS20950	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTV95_RS20960	COG4208	sulfate ABC transporter
CTV95_RS20965	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CTV95_RS20980	COG0667	Aldo Keto reductase
CTV95_RS20985	COG1902	pentaerythritol trinitrate reductase activity
CTV95_RS21010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTV95_RS21015	COG2819	hydrolase of the alpha beta superfamily
CTV95_RS21030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CTV95_RS21035	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CTV95_RS21040	COG0513	Belongs to the DEAD box helicase family
CTV95_RS21045	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CTV95_RS21050	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CTV95_RS21065	COG3026	antisigma factor binding
CTV95_RS21070	COG3086	response to oxidative stress
CTV95_RS21080	COG0481	GTPase activity
CTV95_RS21090	COG0571	ribonuclease III activity
CTV95_RS21095	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CTV95_RS21100	COG1381	Involved in DNA repair and RecF pathway recombination
CTV95_RS21105	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CTV95_RS21110	COG0736	holo-[acyl-carrier-protein] synthase activity
CTV95_RS21115	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTV95_RS21120	COG2200	EAL domain
CTV95_RS21130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTV95_RS21135	COG2274	protein secretion by the type I secretion system
CTV95_RS21155	COG3287	FIST C domain
CTV95_RS21155	COG2200	EAL domain
CTV95_RS21155	COG2199	diguanylate cyclase activity
CTV95_RS21165	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CTV95_RS21170	COG0560	Phosphoserine phosphatase
CTV95_RS21180	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CTV95_RS21185	COG0047	phosphoribosylformylglycinamidine synthase activity
CTV95_RS21185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTV95_RS21190	COG2205	protein histidine kinase activity
CTV95_RS21195	COG3170	Tfp pilus assembly protein FimV
CTV95_RS21200	COG2204	response regulator
CTV95_RS21205	COG0347	Belongs to the P(II) protein family
CTV95_RS21210	COG4677	pectinesterase activity
CTV95_RS21220	COG1017	nitric oxide dioxygenase activity
CTV95_RS21220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTV95_RS21225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CTV95_RS21230	COG2814	Major facilitator Superfamily
CTV95_RS21235	COG3683	transport system, periplasmic component
CTV95_RS21240	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CTV95_RS21250	COG0840	transmembrane signaling receptor activity
CTV95_RS21260	COG1120	ATPase activity
CTV95_RS21265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTV95_RS21275	COG0483	inositol monophosphate 1-phosphatase activity
CTV95_RS21280	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CTV95_RS21285	COG1959	2 iron, 2 sulfur cluster binding
CTV95_RS21290	COG1104	cysteine desulfurase activity
CTV95_RS21295	COG0822	iron-sulfur transferase activity
CTV95_RS21300	COG0316	Belongs to the HesB IscA family
CTV95_RS21305	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CTV95_RS21310	COG0443	Heat shock 70 kDa protein
CTV95_RS21315	COG0633	Ferredoxin
CTV95_RS21320	COG2975	iron-sulfur cluster assembly
CTV95_RS21325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CTV95_RS21335	COG1737	Transcriptional regulator
CTV95_RS21340	COG2897	thiosulfate sulfurtransferase activity
CTV95_RS21345	COG1486	melibiose metabolic process
CTV95_RS21355	COG0105	UTP biosynthetic process
CTV95_RS21360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CTV95_RS21370	COG1426	Protein conserved in bacteria
CTV95_RS21375	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CTV95_RS21380	COG0124	histidyl-tRNA synthetase
CTV95_RS21385	COG2976	Protein conserved in bacteria
CTV95_RS21390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTV95_RS21395	COG1160	GTP binding
CTV95_RS21410	COG1645	bacterial-type flagellum-dependent swarming motility
CTV95_RS21425	COG1570	exodeoxyribonuclease VII activity
CTV95_RS21435	COG0517	IMP dehydrogenase activity
CTV95_RS21435	COG0516	GMP reductase activity
CTV95_RS21440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTV95_RS21440	COG0519	Catalyzes the synthesis of GMP from XMP
CTV95_RS21470	COG3423	Transcriptional regulator
CTV95_RS21500	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTV95_RS21540	COG3706	GGDEF domain
CTV95_RS21545	COG1064	alcohol dehydrogenase
CTV95_RS21560	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
CTV95_RS21565	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CTV95_RS21570	COG0351	phosphomethylpyrimidine kinase
CTV95_RS21575	COG3223	Belongs to the PsiE family
CTV95_RS21580	COG1597	lipid kinase activity
CTV95_RS21585	COG0826	peptidase U32
CTV95_RS21590	COG0435	Glutathione S-transferase
CTV95_RS21605	COG0745	RESPONSE REGULATOR receiver
CTV95_RS21610	COG2205	protein histidine kinase activity
CTV95_RS21615	COG0477	Major facilitator Superfamily
CTV95_RS21625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTV95_RS21630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTV95_RS21635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTV95_RS21640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CTV95_RS21655	COG1874	Beta-galactosidase
CTV95_RS21660	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CTV95_RS21665	COG3833	ABC-type maltose transport systems, permease component
CTV95_RS21670	COG1175	transmembrane transport
CTV95_RS21675	COG2182	Extracellular solute-binding protein
CTV95_RS21680	COG3842	ATPase activity
CTV95_RS21690	COG4580	involved in the transport of maltose and maltodextrins
CTV95_RS21695	COG1609	Transcriptional regulator
CTV95_RS21705	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CTV95_RS21710	COG2239	Acts as a magnesium transporter
CTV95_RS21715	COG1846	Transcriptional regulator
CTV95_RS21720	COG1764	response to oxidative stress
CTV95_RS21740	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CTV95_RS21745	COG0573	inorganic phosphate transmembrane transporter activity
CTV95_RS21750	COG0581	inorganic phosphate transmembrane transporter activity
CTV95_RS21755	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CTV95_RS21765	COG1760	l-serine dehydratase
CTV95_RS21770	COG0814	amino acid
CTV95_RS21775	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CTV95_RS21780	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CTV95_RS21785	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTV95_RS21790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTV95_RS21800	COG0215	cysteine-tRNA ligase activity
CTV95_RS21805	COG2501	S4 domain
CTV95_RS21810	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CTV95_RS21815	COG5001	Diguanylate cyclase
CTV95_RS21815	COG2203	Gaf domain
CTV95_RS21815	COG3706	GGDEF domain
CTV95_RS21815	COG4251	negative regulation of phosphorylation
CTV95_RS21820	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CTV95_RS21825	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CTV95_RS21830	COG0463	Glycosyl transferase, family 2
CTV95_RS21835	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CTV95_RS21835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTV95_RS21840	COG0726	polysaccharide deacetylase
CTV95_RS21845	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CTV95_RS21850	COG2076	Multidrug Resistance protein
CTV95_RS21855	COG2076	Multidrug Resistance protein
CTV95_RS21860	COG3842	ATPase activity
CTV95_RS21875	COG1447	Phosphotransferase system cellobiose-specific component IIA
CTV95_RS21905	COG1696	Membrane protein involved in D-alanine export
CTV95_RS21910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTV95_RS21925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTV95_RS21935	COG1902	pentaerythritol trinitrate reductase activity
CTV95_RS21955	COG0604	alcohol dehydrogenase
CTV95_RS21955	COG3321	synthase
CTV95_RS21970	COG3264	Mechanosensitive ion channel
CTV95_RS21970	COG1511	domain protein
CTV95_RS21980	COG4948	Mandelate Racemase Muconate Lactonizing
CTV95_RS21985	COG0436	Aminotransferase
CTV95_RS21995	COG3266	domain, Protein
CTV95_RS22000	COG3866	Pectate lyase
CTV95_RS22080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTV95_RS22085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTV95_RS22090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTV95_RS22095	COG1120	ATPase activity
CTV95_RS22105	COG0513	Belongs to the DEAD box helicase family
CTV95_RS22230	COG0582	viral genome integration into host DNA
CTV95_RS22240	COG2116	formate transmembrane transporter activity
CTV95_RS22250	COG0579	oxidoreductase
CTV95_RS22255	COG0583	DNA-binding transcription factor activity
CTV95_RS22260	COG1028	Short-chain dehydrogenase reductase Sdr
CTV95_RS22265	COG2067	long-chain fatty acid transport protein
CTV95_RS22270	COG3691	Protein conserved in bacteria
CTV95_RS22275	COG4106	trans-aconitate 2-methyltransferase activity
CTV95_RS22285	COG0183	Belongs to the thiolase family
CTV95_RS22290	COG1024	Enoyl-CoA hydratase
CTV95_RS22290	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTV95_RS22300	COG3188	usher protein
CTV95_RS22320	COG2062	phosphohistidine phosphatase, SixA
CTV95_RS22325	COG2840	Smr protein MutS2
CTV95_RS22330	COG2890	protein-(glutamine-N5) methyltransferase activity
CTV95_RS22335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CTV95_RS22340	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CTV95_RS22345	COG0730	response to heat
CTV95_RS22350	COG3101	peptidyl-lysine hydroxylation
CTV95_RS22365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTV95_RS22365	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CTV95_RS22370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTV95_RS22380	COG0697	spore germination