locus-tag	class	description
EH203_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EH203_RS00010	COG0592	DNA-directed DNA polymerase activity
EH203_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EH203_RS00020	COG0187	DNA topoisomerase II activity
EH203_RS00035	COG0840	transmembrane signaling receptor activity
EH203_RS00040	COG1609	Transcriptional regulator
EH203_RS00045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH203_RS00050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH203_RS00055	COG1447	Phosphotransferase system cellobiose-specific component IIA
EH203_RS00060	COG2723	6-phospho-beta-galactosidase activity
EH203_RS00065	COG0561	phosphatase activity
EH203_RS00075	COG0747	negative chemotaxis
EH203_RS00080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EH203_RS00095	COG0601	transmembrane transport
EH203_RS00100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH203_RS00115	COG1116	anion transmembrane transporter activity
EH203_RS00120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH203_RS00125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH203_RS00130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH203_RS00140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH203_RS00140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH203_RS00145	COG2723	6-phospho-beta-galactosidase activity
EH203_RS00155	COG0823	Involved in the tonB-independent uptake of proteins
EH203_RS00160	COG5645	(Lipo)protein
EH203_RS00165	COG0071	Belongs to the small heat shock protein (HSP20) family
EH203_RS00170	COG0071	Belongs to the small heat shock protein (HSP20) family
EH203_RS00175	COG0569	domain protein
EH203_RS00175	COG2985	domain, Protein
EH203_RS00180	COG0471	metal ion transport
EH203_RS00185	COG3290	protein histidine kinase activity
EH203_RS00190	COG4565	transcriptional regulatory protein
EH203_RS00200	COG3493	citrate carrier protein
EH203_RS00205	COG0747	negative chemotaxis
EH203_RS00210	COG0601	transmembrane transport
EH203_RS00215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH203_RS00220	COG0444	Belongs to the ABC transporter superfamily
EH203_RS00225	COG4608	Belongs to the ABC transporter superfamily
EH203_RS00235	COG4104	PAAR repeat-containing protein
EH203_RS00235	COG3209	COG3209 Rhs family protein
EH203_RS00245	COG4104	PAAR repeat-containing protein
EH203_RS00245	COG3209	COG3209 Rhs family protein
EH203_RS00270	COG3501	Rhs element vgr protein
EH203_RS00280	COG3977	Valine--pyruvate aminotransferase
EH203_RS00305	COG3118	belongs to the thioredoxin family
EH203_RS00305	COG0457	Tetratricopeptide repeat
EH203_RS00310	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EH203_RS00320	COG1215	transferase activity, transferring glycosyl groups
EH203_RS00325	COG1192	Involved in chromosome partitioning
EH203_RS00350	COG2200	EAL domain
EH203_RS00350	COG2199	diguanylate cyclase activity
EH203_RS00355	COG1301	dicarboxylic acid transport
EH203_RS00360	COG0612	Peptidase, M16
EH203_RS00365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH203_RS00370	COG1295	ribonuclease BN
EH203_RS00375	COG0477	Major facilitator Superfamily
EH203_RS00385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EH203_RS00390	COG0425	Belongs to the sulfur carrier protein TusA family
EH203_RS00400	COG3714	YhhN family
EH203_RS00415	COG3776	membrane
EH203_RS00420	COG0742	ribosomal rna small subunit methyltransferase
EH203_RS00425	COG0552	protein localization to endoplasmic reticulum
EH203_RS00430	COG2884	Cell division ATP-binding protein ftsE
EH203_RS00435	COG2177	Part of the ABC transporter FtsEX involved in
EH203_RS00450	COG0683	leucine binding
EH203_RS00455	COG0559	Belongs to the binding-protein-dependent transport system permease family
EH203_RS00460	COG4177	L-phenylalanine transmembrane transporter activity
EH203_RS00465	COG0411	ABC transporter
EH203_RS00470	COG0410	ABC transporter
EH203_RS00475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH203_RS00480	COG0840	transmembrane signaling receptor activity
EH203_RS00485	COG0840	transmembrane signaling receptor activity
EH203_RS00490	COG0840	transmembrane signaling receptor activity
EH203_RS00495	COG0840	transmembrane signaling receptor activity
EH203_RS00500	COG2610	gluconate transmembrane transporter activity
EH203_RS00505	COG3622	Belongs to the hyi family
EH203_RS00510	COG0235	Class ii aldolase
EH203_RS00515	COG3395	kinase activity
EH203_RS00520	COG2084	Dehydrogenase
EH203_RS00525	COG1349	DNA-binding transcription factor activity
EH203_RS00565	COG3609	addiction module antidote protein, CC2985 family
EH203_RS00570	COG1653	transport
EH203_RS00575	COG1175	transmembrane transport
EH203_RS00580	COG0395	ABC-type sugar transport system, permease component
EH203_RS00590	COG0584	glycerophosphoryl diester phosphodiesterase
EH203_RS00605	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EH203_RS00620	COG2205	protein histidine kinase activity
EH203_RS00625	COG0745	RESPONSE REGULATOR receiver
EH203_RS00630	COG3678	ATP-independent chaperone mediated protein folding
EH203_RS00645	COG3831	ATPase activity
EH203_RS00650	COG0714	Associated with various cellular activities
EH203_RS00660	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EH203_RS00670	COG2814	Major facilitator Superfamily
EH203_RS00675	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EH203_RS00680	COG0205	6-phosphofructokinase activity
EH203_RS00685	COG0583	DNA-binding transcription factor activity
EH203_RS00725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH203_RS00730	COG1116	anion transmembrane transporter activity
EH203_RS00735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EH203_RS00740	COG2957	Belongs to the agmatine deiminase family
EH203_RS00755	COG0149	triose-phosphate isomerase activity
EH203_RS00765	COG3152	Membrane
EH203_RS00775	COG1494	fructose-1,6-bisphosphatase
EH203_RS00785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EH203_RS00790	COG3074	FtsZ-dependent cytokinesis
EH203_RS00795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EH203_RS00800	COG1575	Belongs to the MenA family. Type 1 subfamily
EH203_RS00805	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EH203_RS00810	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EH203_RS00815	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EH203_RS00820	COG1609	Transcriptional regulator
EH203_RS00825	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EH203_RS00830	COG0254	rRNA binding
EH203_RS00835	COG1598	PFAM Uncharacterised protein family UPF0150
EH203_RS00855	COG1120	ATPase activity
EH203_RS00860	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
EH203_RS00865	COG0626	cystathionine gamma-synthase activity
EH203_RS00870	COG0527	aspartate kinase activity
EH203_RS00870	COG0460	homoserine dehydrogenase
EH203_RS00875	COG3842	ATPase activity
EH203_RS00890	COG4149	molybdate abc transporter
EH203_RS00895	COG1609	Transcriptional regulator
EH203_RS00900	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EH203_RS00915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH203_RS00930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EH203_RS00935	COG4206	TonB-dependent receptor
EH203_RS00940	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EH203_RS00975	COG1879	ABC-type sugar transport system periplasmic component
EH203_RS00980	COG1129	ABC transporter
EH203_RS00985	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH203_RS00990	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH203_RS00995	COG0583	DNA-binding transcription factor activity
EH203_RS01000	COG3085	chromosome segregation
EH203_RS01020	COG3978	acetolactate synthase activity
EH203_RS01025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EH203_RS01030	COG0129	dihydroxy-acid dehydratase activity
EH203_RS01050	COG0583	DNA-binding transcription factor activity
EH203_RS01055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EH203_RS01070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EH203_RS01070	COG0506	proline dehydrogenase activity
EH203_RS01070	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EH203_RS01075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH203_RS01085	COG0248	Ppx GppA phosphatase
EH203_RS01090	COG0513	Belongs to the DEAD box helicase family
EH203_RS01095	COG3118	belongs to the thioredoxin family
EH203_RS01100	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EH203_RS01105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH203_RS01110	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EH203_RS01115	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EH203_RS01120	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EH203_RS01125	COG1088	dTDP-glucose 4,6-dehydratase activity
EH203_RS01130	COG0456	acetyltransferase
EH203_RS01135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EH203_RS01140	COG2244	polysaccharide biosynthetic process
EH203_RS01145	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EH203_RS01155	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EH203_RS01160	COG1113	amino acid transport
EH203_RS01190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EH203_RS01200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH203_RS01205	COG0765	amino acid transport
EH203_RS01210	COG1126	abc transporter atp-binding protein
EH203_RS01220	COG1126	abc transporter atp-binding protein
EH203_RS01225	COG0765	amino acid transport
EH203_RS01230	COG4597	amino acid ABC transporter
EH203_RS01235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH203_RS01255	COG1802	Transcriptional regulator
EH203_RS01260	COG3071	HemY protein
EH203_RS01265	COG2959	enzyme of heme biosynthesis
EH203_RS01275	COG0181	hydroxymethylbilane synthase activity
EH203_RS01285	COG2814	Major facilitator Superfamily
EH203_RS01290	COG1965	Belongs to the frataxin family
EH203_RS01300	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EH203_RS01315	COG1011	Hydrolase
EH203_RS01320	COG0210	DNA helicase
EH203_RS01325	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EH203_RS01330	COG0598	Magnesium transport protein CorA
EH203_RS01335	COG3180	Ammonia monooxygenase
EH203_RS01345	COG2050	protein possibly involved in aromatic compounds catabolism
EH203_RS01350	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EH203_RS01355	COG0514	ATP-dependent DNA helicase (RecQ)
EH203_RS01360	COG1280	lysine exporter protein (LysE YggA)
EH203_RS01365	COG1280	lysine exporter protein (LysE YggA)
EH203_RS01370	COG2267	carboxylic ester hydrolase activity
EH203_RS01375	COG0561	phosphatase activity
EH203_RS01380	COG0584	glycerophosphoryl diester phosphodiesterase
EH203_RS01385	COG2271	Major facilitator Superfamily
EH203_RS01390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EH203_RS01395	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EH203_RS01400	COG0247	lactate metabolic process
EH203_RS01405	COG1741	Belongs to the pirin family
EH203_RS01410	COG1609	Transcriptional regulator
EH203_RS01415	COG3265	gluconokinase activity
EH203_RS01420	COG2610	gluconate transmembrane transporter activity
EH203_RS01425	COG2095	MarC family integral membrane protein
EH203_RS01430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EH203_RS01440	COG3275	phosphorelay sensor kinase activity
EH203_RS01445	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EH203_RS01450	COG1523	belongs to the glycosyl hydrolase 13 family
EH203_RS01460	COG0297	glycogen (starch) synthase activity
EH203_RS01465	COG0058	SHG alpha-glucan phosphorylase activity
EH203_RS01470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EH203_RS01475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH203_RS01485	COG0705	Rhomboid family
EH203_RS01490	COG1349	DNA-binding transcription factor activity
EH203_RS01495	COG0058	SHG alpha-glucan phosphorylase activity
EH203_RS01500	COG1640	4-alpha-glucanotransferase
EH203_RS01505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EH203_RS01505	COG0316	Belongs to the HesB IscA family
EH203_RS01510	COG1040	competence protein
EH203_RS01515	COG2267	carboxylic ester hydrolase activity
EH203_RS01520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH203_RS01525	COG1335	isochorismatase
EH203_RS01530	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EH203_RS01540	COG1785	Belongs to the alkaline phosphatase family
EH203_RS01570	COG1414	Transcriptional regulator
EH203_RS01575	COG2183	response to ionizing radiation
EH203_RS01585	COG0840	transmembrane signaling receptor activity
EH203_RS01605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EH203_RS01615	COG4264	IucA IucC family
EH203_RS01620	COG4774	siderophore transport
EH203_RS01625	COG0019	diaminopimelate decarboxylase activity
EH203_RS01630	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH203_RS01635	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EH203_RS01640	COG2814	Major facilitator Superfamily
EH203_RS01655	COG0745	RESPONSE REGULATOR receiver
EH203_RS01665	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EH203_RS01670	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EH203_RS01675	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EH203_RS01680	COG1011	Hydrolase
EH203_RS01690	COG0494	nUDIX hydrolase
EH203_RS01700	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EH203_RS01725	COG4796	Type ii and iii secretion system protein
EH203_RS01730	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EH203_RS01735	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EH203_RS01750	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EH203_RS01755	COG0546	phosphoglycolate phosphatase activity
EH203_RS01765	COG1473	amidohydrolase
EH203_RS01790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EH203_RS01790	COG1648	precorrin-2 dehydrogenase activity
EH203_RS01795	COG2146	nitrite reductase [NAD(P)H] activity
EH203_RS01800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EH203_RS01805	COG4948	Mandelate Racemase Muconate Lactonizing
EH203_RS01810	COG0747	negative chemotaxis
EH203_RS01815	COG0601	transmembrane transport
EH203_RS01825	COG0444	Belongs to the ABC transporter superfamily
EH203_RS01830	COG4608	Belongs to the ABC transporter superfamily
EH203_RS01835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EH203_RS01860	COG0582	viral genome integration into host DNA
EH203_RS01880	COG3311	Transcriptional regulator
EH203_RS01905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH203_RS01910	COG1765	OsmC-like protein
EH203_RS01915	COG3954	Phosphoribulokinase
EH203_RS01920	COG3089	Belongs to the UPF0270 family
EH203_RS01925	COG0429	hydrolase of the alpha beta-hydrolase fold
EH203_RS01935	COG0488	(ABC) transporter
EH203_RS01940	COG2249	NAD(P)H dehydrogenase (quinone) activity
EH203_RS01945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EH203_RS01945	COG0475	glutathione-regulated potassium exporter activity
EH203_RS01950	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EH203_RS01955	COG1047	Peptidyl-prolyl cis-trans
EH203_RS01960	COG2900	Belongs to the SlyX family
EH203_RS01965	COG0545	Peptidyl-prolyl cis-trans isomerase
EH203_RS01980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EH203_RS01985	COG0642	Histidine kinase
EH203_RS01990	COG0745	RESPONSE REGULATOR receiver
EH203_RS02000	COG2964	Protein conserved in bacteria
EH203_RS02005	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EH203_RS02010	COG2923	Belongs to the DsrF TusC family
EH203_RS02015	COG2168	tRNA wobble position uridine thiolation
EH203_RS02020	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EH203_RS02025	COG0049	tRNA binding
EH203_RS02030	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EH203_RS02050	COG0051	transcription antitermination factor activity, RNA binding
EH203_RS02055	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EH203_RS02060	COG0088	Forms part of the polypeptide exit tunnel
EH203_RS02070	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EH203_RS02075	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EH203_RS02080	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EH203_RS02085	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EH203_RS02090	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EH203_RS02095	COG0255	Belongs to the universal ribosomal protein uL29 family
EH203_RS02100	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EH203_RS02105	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EH203_RS02110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EH203_RS02115	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EH203_RS02120	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EH203_RS02125	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EH203_RS02130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EH203_RS02135	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EH203_RS02140	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EH203_RS02145	COG1841	ribosomal large subunit assembly
EH203_RS02150	COG0200	Binds to the 23S rRNA
EH203_RS02155	COG0201	protein transport
EH203_RS02160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EH203_RS02165	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EH203_RS02175	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EH203_RS02180	COG0202	RNA polymerase activity
EH203_RS02185	COG0203	ribosomal protein L17
EH203_RS02190	COG3036	rescue of stalled ribosome
EH203_RS02195	COG1970	mechanosensitive ion channel activity
EH203_RS02200	COG0569	domain protein
EH203_RS02205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EH203_RS02205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EH203_RS02210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EH203_RS02215	COG0242	peptide deformylase activity
EH203_RS02220	COG0758	DNA mediated transformation
EH203_RS02225	COG2922	Belongs to the Smg family
EH203_RS02230	COG0551	DNA topoisomerase type I activity
EH203_RS02235	COG0009	L-threonylcarbamoyladenylate synthase
EH203_RS02240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EH203_RS02250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EH203_RS02275	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EH203_RS02280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EH203_RS02290	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EH203_RS02300	COG1410	methionine synthase
EH203_RS02300	COG0646	methionine synthase
EH203_RS02305	COG2207	Transcriptional regulator
EH203_RS02315	COG0471	metal ion transport
EH203_RS02325	COG0527	aspartate kinase activity
EH203_RS02330	COG0166	Belongs to the GPI family
EH203_RS02340	COG1509	lysine 2,3-aminomutase activity
EH203_RS02345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EH203_RS02360	COG3040	lipid binding
EH203_RS02365	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EH203_RS02370	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EH203_RS02375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EH203_RS02380	COG1053	succinate dehydrogenase
EH203_RS02385	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EH203_RS02390	COG3264	Mechanosensitive ion channel
EH203_RS02390	COG1511	domain protein
EH203_RS02395	COG0688	phosphatidylethanolamine metabolic process
EH203_RS02400	COG1162	GTPase activity
EH203_RS02405	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EH203_RS02430	COG2814	Major facilitator Superfamily
EH203_RS02450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH203_RS02455	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EH203_RS02475	COG1064	alcohol dehydrogenase
EH203_RS02485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH203_RS02500	COG1136	(ABC) transporter
EH203_RS02530	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EH203_RS02535	COG0450	alkyl hydroperoxide reductase
EH203_RS02545	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EH203_RS02550	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EH203_RS02550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EH203_RS02555	COG0802	atpase or kinase
EH203_RS02560	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH203_RS02565	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EH203_RS02570	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EH203_RS02575	COG1923	regulation of RNA biosynthetic process
EH203_RS02580	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EH203_RS02585	COG0330	HflC and HflK could
EH203_RS02590	COG0330	HflC and HflK could
EH203_RS02595	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EH203_RS02600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EH203_RS02610	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EH203_RS02615	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EH203_RS02620	COG1678	Uncharacterized ACR, COG1678
EH203_RS02625	COG0189	ligase activity
EH203_RS02630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EH203_RS02635	COG2356	endonuclease I
EH203_RS02640	COG3091	SprT-like family
EH203_RS02645	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EH203_RS02650	COG1166	arginine decarboxylase activity
EH203_RS02660	COG0501	Belongs to the peptidase M48B family
EH203_RS02665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EH203_RS02670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EH203_RS02675	COG0126	phosphoglycerate kinase activity
EH203_RS02680	COG0191	fructose-bisphosphate aldolase activity
EH203_RS02685	COG0668	transmembrane transport
EH203_RS02690	COG1279	arginine transmembrane transporter activity
EH203_RS02700	COG0583	DNA-binding transcription factor activity
EH203_RS02705	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EH203_RS02710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH203_RS02715	COG0604	alcohol dehydrogenase
EH203_RS02720	COG0583	DNA-binding transcription factor activity
EH203_RS02725	COG0840	transmembrane signaling receptor activity
EH203_RS02730	COG0488	(ABC) transporter
EH203_RS02740	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EH203_RS02745	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EH203_RS02755	COG2207	Transcriptional regulator
EH203_RS02755	COG3708	Transcriptional regulator
EH203_RS02760	COG3045	CreA protein
EH203_RS02765	COG0745	RESPONSE REGULATOR receiver
EH203_RS02770	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EH203_RS02785	COG0083	homoserine kinase activity
EH203_RS02795	COG3022	response to hydroperoxide
EH203_RS02800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EH203_RS02805	COG0745	RESPONSE REGULATOR receiver
EH203_RS02805	COG3706	GGDEF domain
EH203_RS02810	COG0521	Mo-molybdopterin cofactor biosynthetic process
EH203_RS02820	COG1584	GPR1 FUN34 yaaH family protein
EH203_RS02825	COG0443	Heat shock 70 kDa protein
EH203_RS02830	COG0484	heat shock protein binding
EH203_RS02835	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EH203_RS02840	COG0583	DNA-binding transcription factor activity
EH203_RS02845	COG0268	Binds directly to 16S ribosomal RNA
EH203_RS02850	COG0196	riboflavin kinase activity
EH203_RS02855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EH203_RS02860	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EH203_RS02865	COG1047	Peptidyl-prolyl cis-trans
EH203_RS02870	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EH203_RS02875	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EH203_RS02880	COG0505	Belongs to the CarA family
EH203_RS02885	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EH203_RS02905	COG2966	Psort location CytoplasmicMembrane, score
EH203_RS02910	COG3610	response to peptide
EH203_RS02915	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EH203_RS02935	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EH203_RS02940	COG2967	ApaG domain
EH203_RS02945	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EH203_RS02950	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EH203_RS02955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH203_RS02960	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EH203_RS02965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EH203_RS02970	COG0564	pseudouridine synthase activity
EH203_RS02975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH203_RS02980	COG0417	DNA replication proofreading
EH203_RS02985	COG3706	GGDEF domain
EH203_RS02990	COG0586	Pfam SNARE associated Golgi protein
EH203_RS02995	COG0440	acetolactate synthase activity
EH203_RS03000	COG0028	Belongs to the TPP enzyme family
EH203_RS03005	COG3507	Belongs to the glycosyl hydrolase 43 family
EH203_RS03010	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EH203_RS03015	COG1178	ABC-type Fe3 transport system permease component
EH203_RS03020	COG4143	(ABC) transporter
EH203_RS03025	COG4533	DNA binding
EH203_RS03035	COG0840	transmembrane signaling receptor activity
EH203_RS03055	COG0066	3-isopropylmalate dehydratase activity
EH203_RS03060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EH203_RS03065	COG0473	3-isopropylmalate dehydrogenase activity
EH203_RS03070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EH203_RS03080	COG0028	Belongs to the TPP enzyme family
EH203_RS03090	COG1609	Transcriptional regulator
EH203_RS03100	COG2001	Belongs to the MraZ family
EH203_RS03105	COG0275	rRNA processing
EH203_RS03110	COG3116	cell division
EH203_RS03115	COG0768	penicillin binding
EH203_RS03125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EH203_RS03130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH203_RS03135	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EH203_RS03140	COG0772	Belongs to the SEDS family
EH203_RS03145	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EH203_RS03150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EH203_RS03155	COG1181	Belongs to the D-alanine--D-alanine ligase family
EH203_RS03160	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EH203_RS03165	COG0849	cell division
EH203_RS03170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EH203_RS03175	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EH203_RS03190	COG0653	protein targeting
EH203_RS03195	COG0494	nUDIX hydrolase
EH203_RS03200	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EH203_RS03205	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EH203_RS03210	COG0237	dephospho-CoA kinase activity
EH203_RS03215	COG0516	GMP reductase activity
EH203_RS03220	COG1459	type II secretion system
EH203_RS03225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EH203_RS03230	COG4969	Belongs to the N-Me-Phe pilin family
EH203_RS03235	COG0157	Belongs to the NadC ModD family
EH203_RS03240	COG3248	Nucleoside-binding outer membrane protein
EH203_RS03245	COG3023	N-Acetylmuramoyl-L-alanine amidase
EH203_RS03250	COG3725	Membrane protein required for beta-lactamase induction
EH203_RS03255	COG3940	Belongs to the glycosyl hydrolase 43 family
EH203_RS03260	COG2211	Major facilitator Superfamily
EH203_RS03265	COG1113	amino acid transport
EH203_RS03270	COG2186	Transcriptional regulator
EH203_RS03275	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EH203_RS03280	COG0508	dehydrogenase complex catalyzes the overall conversion of
EH203_RS03285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH203_RS03300	COG2814	Major facilitator Superfamily
EH203_RS03305	COG1073	alpha beta
EH203_RS03315	COG2079	MmgE PrpD family protein
EH203_RS03320	COG2207	Transcriptional regulator
EH203_RS03330	COG0640	Transcriptional regulator
EH203_RS03350	COG3112	Uncharacterised protein family (UPF0231)
EH203_RS03355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EH203_RS03370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH203_RS03375	COG1609	Transcriptional regulator
EH203_RS03395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EH203_RS03400	COG1882	Formate acetyltransferase
EH203_RS03405	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS03410	COG2731	YhcH YjgK YiaL family protein
EH203_RS03425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EH203_RS03430	COG1454	alcohol dehydrogenase
EH203_RS03435	COG3395	kinase activity
EH203_RS03440	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EH203_RS03445	COG1349	DNA-binding transcription factor activity
EH203_RS03455	COG0803	Belongs to the bacterial solute-binding protein 9 family
EH203_RS03460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH203_RS03465	COG1121	(ABC) transporter
EH203_RS03475	COG2971	BadF BadG BcrA BcrD
EH203_RS03495	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EH203_RS03505	COG1175	transmembrane transport
EH203_RS03510	COG0395	ABC-type sugar transport system, permease component
EH203_RS03530	COG0629	single-stranded DNA binding
EH203_RS03535	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EH203_RS03540	COG0432	Pfam Uncharacterised protein family UPF0047
EH203_RS03575	COG1451	nucleotide metabolic process
EH203_RS03580	COG1448	Aminotransferase
EH203_RS03590	COG1522	sequence-specific DNA binding
EH203_RS03600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EH203_RS03605	COG0305	Participates in initiation and elongation during chromosome replication
EH203_RS03615	COG2124	cytochrome p450
EH203_RS03625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EH203_RS03645	COG0583	DNA-binding transcription factor activity
EH203_RS03650	COG0019	diaminopimelate decarboxylase activity
EH203_RS03670	COG1447	Phosphotransferase system cellobiose-specific component IIA
EH203_RS03675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH203_RS03680	COG2723	6-phospho-beta-galactosidase activity
EH203_RS03685	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH203_RS03690	COG2186	Transcriptional regulator
EH203_RS03700	COG0318	PFAM AMP-dependent synthetase and ligase
EH203_RS03700	COG0204	Acyl-transferase
EH203_RS03705	COG0477	Major facilitator Superfamily
EH203_RS03710	COG2153	protein acetylation
EH203_RS03720	COG0840	transmembrane signaling receptor activity
EH203_RS03725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EH203_RS03730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EH203_RS03735	COG1872	DUF167
EH203_RS03740	COG0762	integral membrane protein
EH203_RS03745	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EH203_RS03750	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EH203_RS03755	COG2805	Type II/IV secretion system protein
EH203_RS03760	COG3706	GGDEF domain
EH203_RS03765	COG0840	transmembrane signaling receptor activity
EH203_RS03770	COG1959	2 iron, 2 sulfur cluster binding
EH203_RS03775	COG0557	exoribonuclease II activity
EH203_RS03780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH203_RS03785	COG0840	transmembrane signaling receptor activity
EH203_RS03790	COG3766	membrane
EH203_RS03810	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EH203_RS03815	COG1690	Belongs to the RtcB family
EH203_RS03820	COG0840	transmembrane signaling receptor activity
EH203_RS03825	COG1073	alpha beta
EH203_RS03830	COG0360	Binds together with S18 to 16S ribosomal RNA
EH203_RS03835	COG2965	DNA replication, synthesis of RNA primer
EH203_RS03840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EH203_RS03845	COG0359	binds to the 23S rRNA
EH203_RS03855	COG3061	Opacity-associated protein A
EH203_RS03860	COG0545	Peptidyl-prolyl cis-trans isomerase
EH203_RS03865	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EH203_RS03870	COG3961	Belongs to the TPP enzyme family
EH203_RS03885	COG1733	regulation of RNA biosynthetic process
EH203_RS03890	COG0737	Belongs to the 5'-nucleotidase family
EH203_RS03895	COG1218	3'(2'),5'-bisphosphate nucleotidase
EH203_RS03900	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EH203_RS03910	COG1253	flavin adenine dinucleotide binding
EH203_RS03915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EH203_RS03920	COG0729	surface antigen
EH203_RS03925	COG2911	Protein conserved in bacteria
EH203_RS03930	COG2105	PFAM AIG2 family protein
EH203_RS03935	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EH203_RS03940	COG0840	transmembrane signaling receptor activity
EH203_RS03945	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EH203_RS03950	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EH203_RS03955	COG1968	undecaprenyl-diphosphatase activity
EH203_RS03960	COG0617	tRNA 3'-terminal CCA addition
EH203_RS03965	COG4991	sh3 domain protein
EH203_RS03970	COG3025	triphosphatase activity
EH203_RS03975	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EH203_RS03980	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EH203_RS03980	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EH203_RS03985	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EH203_RS03990	COG3530	Putative quorum-sensing-regulated virulence factor
EH203_RS04005	COG0840	transmembrane signaling receptor activity
EH203_RS04015	COG2271	Major facilitator Superfamily
EH203_RS04020	COG4948	Mandelate Racemase Muconate Lactonizing
EH203_RS04025	COG4948	Mandelate Racemase Muconate Lactonizing
EH203_RS04035	COG2084	Dehydrogenase
EH203_RS04040	COG1929	Belongs to the glycerate kinase type-1 family
EH203_RS04050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EH203_RS04055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EH203_RS04060	COG3956	TIGRFAM MazG family protein
EH203_RS04065	COG0504	CTP synthase activity
EH203_RS04070	COG0148	phosphopyruvate hydratase activity
EH203_RS04105	COG0583	DNA-binding transcription factor activity
EH203_RS04115	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EH203_RS04120	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS04135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EH203_RS04140	COG0602	queuosine metabolic process
EH203_RS04145	COG0720	synthase
EH203_RS04165	COG2200	EAL domain
EH203_RS04175	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EH203_RS04180	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EH203_RS04185	COG0175	sulfate reduction
EH203_RS04195	COG0444	Belongs to the ABC transporter superfamily
EH203_RS04200	COG4172	Belongs to the ABC transporter superfamily
EH203_RS04210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH203_RS04215	COG0584	glycerophosphoryl diester phosphodiesterase
EH203_RS04220	COG1648	precorrin-2 dehydrogenase activity
EH203_RS04220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EH203_RS04225	COG0175	sulfate reduction
EH203_RS04230	COG2895	sulfate adenylyltransferase (ATP) activity
EH203_RS04235	COG0529	Catalyzes the synthesis of activated sulfate
EH203_RS04245	COG1126	abc transporter atp-binding protein
EH203_RS04250	COG0765	amino acid transport
EH203_RS04260	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EH203_RS04265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EH203_RS04270	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EH203_RS04275	COG0585	pseudouridine synthase activity
EH203_RS04280	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EH203_RS04285	COG4942	peptidase
EH203_RS04285	COG1388	LysM domain
EH203_RS04290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH203_RS04295	COG0442	prolyl-tRNA aminoacylation
EH203_RS04300	COG1720	tRNA m6t6A37 methyltransferase activity
EH203_RS04310	COG1464	Belongs to the NlpA lipoprotein family
EH203_RS04315	COG2011	ABC-type metal ion transport system permease component
EH203_RS04320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EH203_RS04325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EH203_RS04360	COG0477	Major facilitator Superfamily
EH203_RS04365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH203_RS04370	COG0045	succinate-CoA ligase (ADP-forming) activity
EH203_RS04370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH203_RS04370	COG1042	CoA-binding domain protein
EH203_RS04380	COG3118	belongs to the thioredoxin family
EH203_RS04385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH203_RS04395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EH203_RS04400	COG2814	Major facilitator Superfamily
EH203_RS04405	COG1566	PFAM secretion protein HlyD family protein
EH203_RS04410	COG1846	Transcriptional regulator
EH203_RS04420	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EH203_RS04425	COG2814	Major facilitator Superfamily
EH203_RS04430	COG2706	6-phosphogluconolactonase activity
EH203_RS04435	COG2113	Glycine betaine
EH203_RS04440	COG4176	ABC-type proline glycine betaine transport system permease component
EH203_RS04445	COG4175	Glycine betaine
EH203_RS04500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EH203_RS04515	COG0436	Aminotransferase
EH203_RS04520	COG0235	Class ii aldolase
EH203_RS04525	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
EH203_RS04530	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EH203_RS04535	COG3501	Rhs element vgr protein
EH203_RS04565	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EH203_RS04570	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EH203_RS04575	COG1403	HNH endonuclease
EH203_RS04580	COG1960	acyl-CoA dehydrogenase activity
EH203_RS04585	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EH203_RS04590	COG0121	glutamine amidotransferase
EH203_RS04595	COG3034	peptidoglycan biosynthetic process
EH203_RS04600	COG2226	methyltransferase
EH203_RS04610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EH203_RS04615	COG2195	Cleaves the N-terminal amino acid of tripeptides
EH203_RS04620	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EH203_RS04640	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EH203_RS04740	COG2026	Addiction module toxin, RelE StbE family
EH203_RS04820	COG2204	response regulator
EH203_RS04880	COG3209	COG3209 Rhs family protein
EH203_RS04940	COG2999	glutathione oxidoreductase activity
EH203_RS04945	COG0583	DNA-binding transcription factor activity
EH203_RS04950	COG2814	Major facilitator Superfamily
EH203_RS04955	COG0745	RESPONSE REGULATOR receiver
EH203_RS04955	COG3706	GGDEF domain
EH203_RS04980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EH203_RS04985	COG2137	regulation of response to DNA damage stimulus
EH203_RS04990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EH203_RS04995	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EH203_RS05025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH203_RS05030	COG1238	metal cluster binding
EH203_RS05035	COG2918	glutathione biosynthetic process
EH203_RS05040	COG1854	S-ribosylhomocysteine lyase activity
EH203_RS05045	COG4137	Cytochrome C assembly protein
EH203_RS05050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EH203_RS05055	COG0228	four-way junction DNA binding
EH203_RS05060	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EH203_RS05065	COG0336	Belongs to the RNA methyltransferase TrmD family
EH203_RS05070	COG0335	large ribosomal subunit rRNA binding
EH203_RS05190	COG4695	Portal protein
EH203_RS05250	COG4974	Belongs to the 'phage' integrase family
EH203_RS05260	COG2264	protein methyltransferase activity
EH203_RS05270	COG3279	Response regulator of the LytR AlgR family
EH203_RS05275	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EH203_RS05280	COG1605	Chorismate mutase
EH203_RS05280	COG0287	Prephenate dehydrogenase
EH203_RS05285	COG1605	Chorismate mutase
EH203_RS05285	COG0077	Prephenate dehydratase
EH203_RS05290	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EH203_RS05295	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH203_RS05300	COG0564	pseudouridine synthase activity
EH203_RS05345	COG3021	interspecies interaction between organisms
EH203_RS05350	COG1388	LysM domain
EH203_RS05350	COG0741	lytic transglycosylase activity
EH203_RS05355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EH203_RS05360	COG2226	methyltransferase
EH203_RS05365	COG0328	RNA-DNA hybrid ribonuclease activity
EH203_RS05370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EH203_RS05380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EH203_RS05390	COG1780	Probably involved in ribonucleotide reductase function
EH203_RS05395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EH203_RS05400	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EH203_RS05405	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EH203_RS05420	COG3842	ATPase activity
EH203_RS05435	COG0288	reversible hydration of carbon dioxide
EH203_RS05440	COG1131	(ABC) transporter
EH203_RS05450	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EH203_RS05455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EH203_RS05460	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EH203_RS05465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EH203_RS05475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH203_RS05480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EH203_RS05485	COG1489	DNA binding
EH203_RS05490	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EH203_RS05495	COG1643	Atp-dependent helicase
EH203_RS05500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EH203_RS05505	COG1120	ATPase activity
EH203_RS05510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH203_RS05525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH203_RS05530	COG0625	glutathione transferase activity
EH203_RS05535	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EH203_RS05540	COG0316	Belongs to the HesB IscA family
EH203_RS05550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH203_RS05555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EH203_RS05560	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EH203_RS05565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH203_RS05570	COG3835	regulator
EH203_RS05575	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EH203_RS05585	COG4208	sulfate ABC transporter
EH203_RS05590	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EH203_RS05600	COG1309	transcriptional regulator
EH203_RS05605	COG0667	Aldo Keto reductase
EH203_RS05610	COG1902	pentaerythritol trinitrate reductase activity
EH203_RS05635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH203_RS05640	COG2819	hydrolase of the alpha beta superfamily
EH203_RS05655	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EH203_RS05660	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
EH203_RS05665	COG0513	Belongs to the DEAD box helicase family
EH203_RS05670	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EH203_RS05675	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EH203_RS05690	COG3026	antisigma factor binding
EH203_RS05695	COG3086	response to oxidative stress
EH203_RS05705	COG0481	GTPase activity
EH203_RS05710	COG0681	Belongs to the peptidase S26 family
EH203_RS05715	COG0571	ribonuclease III activity
EH203_RS05720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EH203_RS05730	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EH203_RS05735	COG0736	holo-[acyl-carrier-protein] synthase activity
EH203_RS05740	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH203_RS05745	COG2200	EAL domain
EH203_RS05755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH203_RS05780	COG2199	diguanylate cyclase activity
EH203_RS05780	COG3287	FIST C domain
EH203_RS05780	COG2200	EAL domain
EH203_RS05790	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EH203_RS05795	COG0560	Phosphoserine phosphatase
EH203_RS05800	COG0590	tRNA wobble adenosine to inosine editing
EH203_RS05805	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EH203_RS05810	COG0047	phosphoribosylformylglycinamidine synthase activity
EH203_RS05810	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EH203_RS05815	COG2205	protein histidine kinase activity
EH203_RS05820	COG3170	Tfp pilus assembly protein FimV
EH203_RS05825	COG2204	response regulator
EH203_RS05830	COG0347	Belongs to the P(II) protein family
EH203_RS05835	COG4677	pectinesterase activity
EH203_RS05845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH203_RS05845	COG1017	nitric oxide dioxygenase activity
EH203_RS05850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EH203_RS05855	COG2814	Major facilitator Superfamily
EH203_RS05860	COG3683	transport system, periplasmic component
EH203_RS05865	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EH203_RS05885	COG1120	ATPase activity
EH203_RS05890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH203_RS05900	COG0483	inositol monophosphate 1-phosphatase activity
EH203_RS05905	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EH203_RS05910	COG1959	2 iron, 2 sulfur cluster binding
EH203_RS05915	COG1104	cysteine desulfurase activity
EH203_RS05920	COG0822	iron-sulfur transferase activity
EH203_RS05925	COG0316	Belongs to the HesB IscA family
EH203_RS05930	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EH203_RS05935	COG0443	Heat shock 70 kDa protein
EH203_RS05940	COG0633	Ferredoxin
EH203_RS05945	COG2975	iron-sulfur cluster assembly
EH203_RS05950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EH203_RS05960	COG1737	Transcriptional regulator
EH203_RS05965	COG2897	thiosulfate sulfurtransferase activity
EH203_RS05970	COG1486	melibiose metabolic process
EH203_RS05975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH203_RS05975	COG1263	PTS System
EH203_RS05975	COG2190	(PTS) system
EH203_RS05980	COG0105	UTP biosynthetic process
EH203_RS05985	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EH203_RS05995	COG1426	Protein conserved in bacteria
EH203_RS06000	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EH203_RS06005	COG0124	histidyl-tRNA synthetase
EH203_RS06010	COG2976	Protein conserved in bacteria
EH203_RS06015	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH203_RS06020	COG1160	GTP binding
EH203_RS06035	COG1645	bacterial-type flagellum-dependent swarming motility
EH203_RS06050	COG1570	exodeoxyribonuclease VII activity
EH203_RS06055	COG0516	GMP reductase activity
EH203_RS06055	COG0517	IMP dehydrogenase activity
EH203_RS06060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EH203_RS06060	COG0519	Catalyzes the synthesis of GMP from XMP
EH203_RS06080	COG3423	Transcriptional regulator
EH203_RS06100	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EH203_RS06155	COG5001	Diguanylate cyclase
EH203_RS06160	COG1064	alcohol dehydrogenase
EH203_RS06165	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EH203_RS06170	COG0351	phosphomethylpyrimidine kinase
EH203_RS06175	COG3223	Belongs to the PsiE family
EH203_RS06180	COG1597	lipid kinase activity
EH203_RS06190	COG0435	Glutathione S-transferase
EH203_RS06205	COG0745	RESPONSE REGULATOR receiver
EH203_RS06210	COG2205	protein histidine kinase activity
EH203_RS06215	COG0477	Major facilitator Superfamily
EH203_RS06220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH203_RS06225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH203_RS06230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH203_RS06235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EH203_RS06250	COG1874	Beta-galactosidase
EH203_RS06255	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EH203_RS06260	COG3833	ABC-type maltose transport systems, permease component
EH203_RS06265	COG1175	transmembrane transport
EH203_RS06270	COG2182	Extracellular solute-binding protein
EH203_RS06275	COG3842	ATPase activity
EH203_RS06280	COG4580	involved in the transport of maltose and maltodextrins
EH203_RS06285	COG1609	Transcriptional regulator
EH203_RS06290	COG1085	galactose-1-phosphate uridylyltransferase
EH203_RS06300	COG2239	Acts as a magnesium transporter
EH203_RS06305	COG1846	Transcriptional regulator
EH203_RS06310	COG1764	response to oxidative stress
EH203_RS06325	COG0248	Ppx GppA phosphatase
EH203_RS06330	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EH203_RS06335	COG0573	inorganic phosphate transmembrane transporter activity
EH203_RS06340	COG0581	inorganic phosphate transmembrane transporter activity
EH203_RS06345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EH203_RS06365	COG1760	l-serine dehydratase
EH203_RS06370	COG0814	amino acid
EH203_RS06375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EH203_RS06380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EH203_RS06385	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH203_RS06390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EH203_RS06400	COG0215	cysteine-tRNA ligase activity
EH203_RS06405	COG2501	S4 domain
EH203_RS06410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EH203_RS06415	COG3706	GGDEF domain
EH203_RS06415	COG5001	Diguanylate cyclase
EH203_RS06415	COG4251	negative regulation of phosphorylation
EH203_RS06415	COG2203	Gaf domain
EH203_RS06420	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EH203_RS06425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EH203_RS06430	COG0463	Glycosyl transferase, family 2
EH203_RS06435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EH203_RS06435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH203_RS06440	COG0726	polysaccharide deacetylase
EH203_RS06445	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EH203_RS06450	COG2076	Multidrug Resistance protein
EH203_RS06455	COG2076	Multidrug Resistance protein
EH203_RS06460	COG3842	ATPase activity
EH203_RS06475	COG1447	Phosphotransferase system cellobiose-specific component IIA
EH203_RS06500	COG1696	Membrane protein involved in D-alanine export
EH203_RS06505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH203_RS06520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH203_RS06545	COG1511	domain protein
EH203_RS06545	COG3264	Mechanosensitive ion channel
EH203_RS06550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EH203_RS06555	COG4948	Mandelate Racemase Muconate Lactonizing
EH203_RS06560	COG0436	Aminotransferase
EH203_RS06570	COG3266	domain, Protein
EH203_RS06575	COG3866	Pectate lyase
EH203_RS06655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH203_RS06680	COG0513	Belongs to the DEAD box helicase family
EH203_RS06755	COG2116	formate transmembrane transporter activity
EH203_RS06765	COG0579	oxidoreductase
EH203_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS06780	COG2067	long-chain fatty acid transport protein
EH203_RS06785	COG3691	Protein conserved in bacteria
EH203_RS06790	COG0183	Belongs to the thiolase family
EH203_RS06795	COG1250	3-hydroxyacyl-CoA dehydrogenase
EH203_RS06795	COG1024	Enoyl-CoA hydratase
EH203_RS06805	COG3188	usher protein
EH203_RS06825	COG2062	phosphohistidine phosphatase, SixA
EH203_RS06830	COG2840	Smr protein MutS2
EH203_RS06835	COG2890	protein-(glutamine-N5) methyltransferase activity
EH203_RS06840	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EH203_RS06845	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
EH203_RS06850	COG0730	response to heat
EH203_RS06855	COG3101	peptidyl-lysine hydroxylation
EH203_RS06865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EH203_RS06865	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EH203_RS06870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EH203_RS06880	COG0697	spore germination
EH203_RS06885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH203_RS06890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EH203_RS06895	COG0101	tRNA pseudouridine synthase activity
EH203_RS06900	COG0586	Pfam SNARE associated Golgi protein
EH203_RS06910	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EH203_RS06915	COG0285	dihydrofolate synthase activity
EH203_RS06920	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EH203_RS06925	COG1286	toxin biosynthetic process
EH203_RS06930	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EH203_RS06935	COG0163	prenyltransferase activity
EH203_RS06945	COG4215	(ABC) transporter
EH203_RS06950	COG4160	amino acid transport
EH203_RS06955	COG4598	ABC transporter
EH203_RS06960	COG1090	epimerase
EH203_RS06965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EH203_RS06970	COG0625	glutathione transferase activity
EH203_RS06975	COG0622	Phosphoesterase
EH203_RS06980	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EH203_RS06985	COG3739	integral membrane protein
EH203_RS06990	COG0857	belongs to the CobB CobQ family
EH203_RS06990	COG0280	phosphate acetyltransferase
EH203_RS06995	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EH203_RS07000	COG3092	negative regulation of chromosome organization
EH203_RS07005	COG3013	Belongs to the UPF0304 family
EH203_RS07010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH203_RS07015	COG0471	metal ion transport
EH203_RS07015	COG0490	domain, Protein
EH203_RS07020	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EH203_RS07025	COG0436	Aminotransferase
EH203_RS07030	COG0583	DNA-binding transcription factor activity
EH203_RS07040	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH203_RS07045	COG0649	NAD binding
EH203_RS07045	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH203_RS07050	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EH203_RS07060	COG1034	ATP synthesis coupled electron transport
EH203_RS07065	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EH203_RS07070	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH203_RS07075	COG0839	Belongs to the complex I subunit 6 family
EH203_RS07080	COG0713	ATP synthesis coupled electron transport
EH203_RS07085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EH203_RS07090	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH203_RS07095	COG1007	ATP synthesis coupled electron transport
EH203_RS07100	COG4575	ribosome binding
EH203_RS07105	COG0366	Alpha amylase catalytic
EH203_RS07110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH203_RS07110	COG1263	PTS System
EH203_RS07125	COG0488	(ABC) transporter
EH203_RS07135	COG4771	TonB-dependent receptor
EH203_RS07160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EH203_RS07160	COG0519	Catalyzes the synthesis of GMP from XMP
EH203_RS07165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH203_RS07170	COG3058	Necessary for formate dehydrogenase activity
EH203_RS07180	COG2149	membrane
EH203_RS07185	COG4890	Cyd operon protein YbgT
EH203_RS07190	COG1294	oxidase, subunit
EH203_RS07195	COG1271	oxidase subunit
EH203_RS07200	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EH203_RS07215	COG3707	response regulator
EH203_RS07225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH203_RS07235	COG1116	anion transmembrane transporter activity
EH203_RS07240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EH203_RS07240	COG2146	nitrite reductase [NAD(P)H] activity
EH203_RS07245	COG0243	molybdopterin cofactor binding
EH203_RS07250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EH203_RS07250	COG1648	precorrin-2 dehydrogenase activity
EH203_RS07255	COG5464	transposase or invertase
EH203_RS07265	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EH203_RS07275	COG1129	ABC transporter
EH203_RS07280	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH203_RS07285	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH203_RS07295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH203_RS07300	COG1070	Carbohydrate kinase
EH203_RS07305	COG0640	Transcriptional regulator
EH203_RS07310	COG1902	pentaerythritol trinitrate reductase activity
EH203_RS07315	COG0626	cystathionine gamma-synthase activity
EH203_RS07330	COG2076	Multidrug Resistance protein
EH203_RS07350	COG0745	RESPONSE REGULATOR receiver
EH203_RS07370	COG0765	amino acid transport
EH203_RS07375	COG0765	amino acid transport
EH203_RS07390	COG5000	phosphorelay sensor kinase activity
EH203_RS07390	COG5002	protein histidine kinase activity
EH203_RS07395	COG0745	RESPONSE REGULATOR receiver
EH203_RS07415	COG4948	Mandelate Racemase Muconate Lactonizing
EH203_RS07425	COG0659	secondary active sulfate transmembrane transporter activity
EH203_RS07455	COG2814	Major facilitator Superfamily
EH203_RS07480	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EH203_RS07485	COG0732	type I restriction modification DNA specificity domain
EH203_RS07490	COG0419	ATPase involved in DNA repair
EH203_RS07535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EH203_RS07550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EH203_RS07560	COG0386	Belongs to the glutathione peroxidase family
EH203_RS07570	COG4227	nucleotidyltransferase activity
EH203_RS07655	COG3451	type IV secretory pathway VirB4
EH203_RS07675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EH203_RS07715	COG1733	regulation of RNA biosynthetic process
EH203_RS07720	COG4221	oxidoreductase activity
EH203_RS07725	COG4221	oxidoreductase activity
EH203_RS07735	COG2207	Transcriptional regulator
EH203_RS07745	COG0667	Aldo Keto reductase
EH203_RS07760	COG0656	L-ascorbic acid biosynthetic process
EH203_RS07775	COG2814	Major facilitator Superfamily
EH203_RS07780	COG0582	viral genome integration into host DNA
EH203_RS07805	COG1113	amino acid transport
EH203_RS07825	COG2197	response regulator
EH203_RS07830	COG0322	excinuclease ABC activity
EH203_RS07835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EH203_RS07940	COG3772	lysozyme
EH203_RS07980	COG4695	Portal protein
EH203_RS08060	COG4974	Belongs to the 'phage' integrase family
EH203_RS08065	COG1403	HNH endonuclease
EH203_RS08070	COG0582	viral genome integration into host DNA
EH203_RS08110	COG1104	cysteine desulfurase activity
EH203_RS08140	COG1560	Kdo2-lipid A biosynthetic process
EH203_RS08145	COG3459	Glycosyltransferase 36 associated
EH203_RS08155	COG3706	GGDEF domain
EH203_RS08165	COG0840	transmembrane signaling receptor activity
EH203_RS08170	COG0697	spore germination
EH203_RS08195	COG2198	Histidine kinase
EH203_RS08195	COG0643	Histidine kinase
EH203_RS08200	COG0835	chemotaxis
EH203_RS08205	COG0840	transmembrane signaling receptor activity
EH203_RS08210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EH203_RS08215	COG2201	protein-glutamate methylesterase activity
EH203_RS08220	COG0745	RESPONSE REGULATOR receiver
EH203_RS08230	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EH203_RS08235	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EH203_RS08250	COG2747	anti-sigma28 factor FlgM
EH203_RS08260	COG1815	bacterial-type flagellum-dependent cell motility
EH203_RS08265	COG1558	bacterial-type flagellum-dependent cell motility
EH203_RS08270	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EH203_RS08275	COG1749	Flagellar hook protein flgE
EH203_RS08280	COG4787	bacterial-type flagellum-dependent cell motility
EH203_RS08285	COG4786	Flagellar basal body rod
EH203_RS08290	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EH203_RS08295	COG1706	bacterial-type flagellum-dependent cell motility
EH203_RS08305	COG1256	bacterial-type flagellum assembly
EH203_RS08345	COG1580	Controls the rotational direction of flagella during chemotaxis
EH203_RS08355	COG2882	bacterial-type flagellum organization
EH203_RS08365	COG1317	bacterial-type flagellum organization
EH203_RS08370	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EH203_RS08380	COG1677	Flagellar hook-basal body complex protein FliE
EH203_RS08405	COG0500	methyltransferase
EH203_RS08445	COG1191	sigma factor activity
EH203_RS08455	COG1702	phosphate starvation-inducible protein PhoH
EH203_RS08470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EH203_RS08475	COG1309	transcriptional regulator
EH203_RS08480	COG1012	belongs to the aldehyde dehydrogenase family
EH203_RS08485	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EH203_RS08490	COG2979	Protein of unknown function (DUF533)
EH203_RS08495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EH203_RS08500	COG1067	ATP-dependent peptidase activity
EH203_RS08515	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
EH203_RS08520	COG3070	regulator of competence-specific genes
EH203_RS08525	COG1289	transmembrane transporter activity
EH203_RS08530	COG3304	Inner membrane component domain
EH203_RS08535	COG0210	DNA helicase
EH203_RS08540	COG1803	Methylglyoxal synthase
EH203_RS08550	COG1832	CoA-binding protein
EH203_RS08555	COG3785	DNA binding
EH203_RS08560	COG1254	Belongs to the acylphosphatase family
EH203_RS08565	COG2920	part of a sulfur-relay system
EH203_RS08570	COG0670	Belongs to the BI1 family
EH203_RS08600	COG0589	response to stress
EH203_RS08605	COG1683	Conserved Protein
EH203_RS08625	COG0840	transmembrane signaling receptor activity
EH203_RS08640	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EH203_RS08645	COG2943	transferase activity, transferring hexosyl groups
EH203_RS08650	COG1560	Kdo2-lipid A biosynthetic process
EH203_RS08655	COG1902	pentaerythritol trinitrate reductase activity
EH203_RS08665	COG2353	YceI-like domain
EH203_RS08670	COG3038	cytochrome b561
EH203_RS08690	COG0418	dihydroorotase activity
EH203_RS08700	COG1530	ribonuclease E activity
EH203_RS08700	COG1530	ribonuclease E activity
EH203_RS08705	COG0564	pseudouridine synthase activity
EH203_RS08710	COG0424	maF-like protein
EH203_RS08715	COG1399	metal-binding, possibly nucleic acid-binding protein
EH203_RS08720	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EH203_RS08725	COG0416	fatty acid biosynthetic process
EH203_RS08730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EH203_RS08735	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EH203_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS08745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH203_RS08750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EH203_RS08755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EH203_RS08760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EH203_RS08765	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EH203_RS08770	COG0470	DNA polymerase III
EH203_RS08775	COG0084	hydrolase, TatD family'
EH203_RS08780	COG1263	PTS System
EH203_RS08780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH203_RS08795	COG0537	adenosine 5'-monophosphoramidase activity
EH203_RS08805	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
EH203_RS08815	COG1472	Belongs to the glycosyl hydrolase 3 family
EH203_RS08820	COG3150	esterase
EH203_RS08825	COG1252	NADH dehydrogenase
EH203_RS08830	COG3134	Outer membrane lipoprotein
EH203_RS08835	COG2814	Major facilitator Superfamily
EH203_RS08845	COG1309	transcriptional regulator
EH203_RS08850	COG0443	Heat shock 70 kDa protein
EH203_RS08860	COG0300	oxidoreductase activity
EH203_RS08865	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EH203_RS08870	COG4591	ABC-type transport system involved in lipoprotein release permease component
EH203_RS08875	COG1136	(ABC) transporter
EH203_RS08880	COG4591	ABC-type transport system involved in lipoprotein release permease component
EH203_RS08885	COG1940	carbohydrate kinase activity
EH203_RS08890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EH203_RS08905	COG2226	methyltransferase
EH203_RS08910	COG4139	cobalamin transport
EH203_RS08915	COG0386	Belongs to the glutathione peroxidase family
EH203_RS08920	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EH203_RS08925	COG0791	NLP P60 protein
EH203_RS08930	COG0095	Lipoate-protein ligase
EH203_RS08940	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EH203_RS08945	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EH203_RS08950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH203_RS08955	COG4558	Periplasmic binding protein
EH203_RS08960	COG3720	iron ion transport
EH203_RS08965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EH203_RS08970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EH203_RS08975	COG0574	Belongs to the PEP-utilizing enzyme family
EH203_RS08975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EH203_RS08980	COG1477	protein flavinylation
EH203_RS08990	COG0628	permease
EH203_RS08995	COG0277	FAD linked oxidase domain protein
EH203_RS08995	COG0247	lactate metabolic process
EH203_RS09000	COG2050	protein possibly involved in aromatic compounds catabolism
EH203_RS09010	COG0316	Belongs to the HesB IscA family
EH203_RS09015	COG0719	Fe-S assembly protein
EH203_RS09020	COG0396	ATPase activity
EH203_RS09025	COG0719	Fe-S assembly protein
EH203_RS09030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH203_RS09035	COG2166	iron-sulfur cluster assembly
EH203_RS09040	COG1376	ErfK ybiS ycfS ynhG family protein
EH203_RS09040	COG1388	LysM domain
EH203_RS09045	COG4238	major outer membrane lipoprotein
EH203_RS09080	COG2382	esterase
EH203_RS09085	COG1957	nucleoside hydrolase
EH203_RS09090	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EH203_RS09095	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EH203_RS09100	COG0437	4 iron, 4 sulfur cluster binding
EH203_RS09105	COG3301	Polysulphide reductase, NrfD
EH203_RS09110	COG1138	Cytochrome C-type biogenesis protein
EH203_RS09115	COG3088	subunit of a heme lyase
EH203_RS09120	COG4235	cytochrome complex assembly
EH203_RS09125	COG4133	protoheme IX ABC transporter activity
EH203_RS09130	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EH203_RS09135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EH203_RS09140	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EH203_RS09145	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EH203_RS09150	COG1138	Cytochrome C-type biogenesis protein
EH203_RS09155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EH203_RS09160	COG3088	subunit of a heme lyase
EH203_RS09160	COG4235	cytochrome complex assembly
EH203_RS09165	COG4235	cytochrome complex assembly
EH203_RS09165	COG3088	subunit of a heme lyase
EH203_RS09170	COG3005	denitrification pathway
EH203_RS09175	COG3043	anaerobic respiration
EH203_RS09180	COG0348	domain, Protein
EH203_RS09185	COG0437	4 iron, 4 sulfur cluster binding
EH203_RS09190	COG0243	molybdopterin cofactor binding
EH203_RS09195	COG3062	negative regulation of establishment of protein localization
EH203_RS09200	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH203_RS09200	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH203_RS09205	COG3850	Histidine kinase
EH203_RS09210	COG2197	response regulator
EH203_RS09235	COG1301	dicarboxylic acid transport
EH203_RS09240	COG2076	Multidrug Resistance protein
EH203_RS09245	COG0561	phosphatase activity
EH203_RS09255	COG1408	metallophosphoesterase
EH203_RS09260	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EH203_RS09275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH203_RS09285	COG1116	anion transmembrane transporter activity
EH203_RS09290	COG3665	Urea carboxylase-associated protein
EH203_RS09300	COG0439	Biotin carboxylase
EH203_RS09310	COG0534	Mate efflux family protein
EH203_RS09315	COG0307	riboflavin synthase, alpha
EH203_RS09320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EH203_RS09325	COG1609	Transcriptional regulator
EH203_RS09335	COG0791	NLP P60 protein
EH203_RS09340	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EH203_RS09345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EH203_RS09350	COG0346	lactoylglutathione lyase activity
EH203_RS09355	COG3313	Fe-S protein
EH203_RS09365	COG3133	Outer membrane lipoprotein
EH203_RS09370	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EH203_RS09375	COG3895	Periplasmic Protein
EH203_RS09380	COG0259	pyridoxamine-phosphate oxidase activity
EH203_RS09385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EH203_RS09390	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EH203_RS09395	COG0625	glutathione transferase activity
EH203_RS09400	COG1301	dicarboxylic acid transport
EH203_RS09405	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EH203_RS09425	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EH203_RS09430	COG0671	phosphoesterase, PA-phosphatase related
EH203_RS09445	COG1129	ABC transporter
EH203_RS09450	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH203_RS09455	COG3959	Transketolase, thiamine diphosphate binding domain
EH203_RS09460	COG3958	Transketolase
EH203_RS09465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EH203_RS09470	COG1082	Xylose isomerase domain protein TIM barrel
EH203_RS09480	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EH203_RS09485	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EH203_RS09490	COG0284	orotidine-5'-phosphate decarboxylase activity
EH203_RS09495	COG0023	Translation Initiation Factor
EH203_RS09505	COG0235	Class ii aldolase
EH203_RS09510	COG1966	Carbon starvation protein
EH203_RS09515	COG4989	oxidoreductase activity
EH203_RS09520	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EH203_RS09525	COG0243	molybdopterin cofactor binding
EH203_RS09530	COG0583	DNA-binding transcription factor activity
EH203_RS09535	COG1609	Transcriptional regulator
EH203_RS09540	COG2271	Major facilitator Superfamily
EH203_RS09550	COG1053	succinate dehydrogenase
EH203_RS09580	COG4171	peptide transport system, permease
EH203_RS09585	COG4168	peptide transport system, permease
EH203_RS09590	COG4166	transmembrane transport
EH203_RS09610	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EH203_RS09615	COG1842	Phage shock protein A
EH203_RS09625	COG1983	PspC domain protein
EH203_RS09640	COG3210	domain, Protein
EH203_RS09650	COG2831	hemolysin activation secretion protein
EH203_RS09655	COG3106	COG3106 Predicted ATPase
EH203_RS09660	COG3768	UPF0283 membrane protein
EH203_RS09675	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EH203_RS09680	COG2866	Carboxypeptidase
EH203_RS09685	COG4166	transmembrane transport
EH203_RS09690	COG0598	Magnesium transport protein CorA
EH203_RS09695	COG0037	tRNA processing
EH203_RS09720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH203_RS09730	COG0840	transmembrane signaling receptor activity
EH203_RS09735	COG2911	Protein conserved in bacteria
EH203_RS09745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EH203_RS09750	COG1643	Atp-dependent helicase
EH203_RS09760	COG3300	MHYT domain
EH203_RS09760	COG5001	Diguanylate cyclase
EH203_RS09765	COG3591	Belongs to the peptidase S1B family
EH203_RS09780	COG2205	protein histidine kinase activity
EH203_RS09785	COG0745	RESPONSE REGULATOR receiver
EH203_RS09810	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS09820	COG0659	secondary active sulfate transmembrane transporter activity
EH203_RS09825	COG0387	Pfam Sodium calcium exchanger
EH203_RS09835	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EH203_RS09855	COG2197	response regulator
EH203_RS09860	COG3850	Histidine kinase
EH203_RS09865	COG2223	nitrite transmembrane transporter activity
EH203_RS09870	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EH203_RS09875	COG1140	nitrate reductase beta subunit
EH203_RS09880	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EH203_RS09885	COG2181	nitrate reductase activity
EH203_RS09890	COG0697	spore germination
EH203_RS09895	COG1846	Transcriptional regulator
EH203_RS09930	COG2261	transglycosylase associated protein
EH203_RS09935	COG2255	four-way junction helicase activity
EH203_RS09945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EH203_RS09960	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS09965	COG3842	ATPase activity
EH203_RS09975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EH203_RS09980	COG1012	belongs to the aldehyde dehydrogenase family
EH203_RS09995	COG1176	ABC-type spermidine putrescine transport system, permease component I
EH203_RS10005	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS10015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EH203_RS10020	COG0840	transmembrane signaling receptor activity
EH203_RS10025	COG0671	phosphoesterase, PA-phosphatase related
EH203_RS10030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EH203_RS10035	COG2011	ABC-type metal ion transport system permease component
EH203_RS10040	COG4948	Mandelate Racemase Muconate Lactonizing
EH203_RS10045	COG1464	Belongs to the NlpA lipoprotein family
EH203_RS10055	COG0583	DNA-binding transcription factor activity
EH203_RS10060	COG4792	protein secretion
EH203_RS10070	COG4794	Type iii secretion
EH203_RS10095	COG1157	protein secretion by the type III secretion system
EH203_RS10125	COG2197	response regulator
EH203_RS10135	COG2200	EAL domain
EH203_RS10195	COG3501	Rhs element vgr protein
EH203_RS10240	COG1802	Transcriptional regulator
EH203_RS10245	COG2831	hemolysin activation secretion protein
EH203_RS10310	COG2211	Major facilitator Superfamily
EH203_RS10315	COG3507	Belongs to the glycosyl hydrolase 43 family
EH203_RS10330	COG1802	Transcriptional regulator
EH203_RS10340	COG0559	Belongs to the binding-protein-dependent transport system permease family
EH203_RS10350	COG0411	ABC transporter
EH203_RS10365	COG0640	Transcriptional regulator
EH203_RS10380	COG1126	abc transporter atp-binding protein
EH203_RS10385	COG0765	amino acid transport
EH203_RS10395	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EH203_RS10405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH203_RS10420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH203_RS10445	COG1609	Transcriptional regulator
EH203_RS10450	COG1263	PTS System
EH203_RS10450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH203_RS10460	COG0483	inositol monophosphate 1-phosphatase activity
EH203_RS10465	COG0346	lactoylglutathione lyase activity
EH203_RS10475	COG0523	cobalamin synthesis protein
EH203_RS10500	COG0583	DNA-binding transcription factor activity
EH203_RS10510	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EH203_RS10515	COG0012	GTP binding
EH203_RS10520	COG0193	aminoacyl-tRNA hydrolase activity
EH203_RS10530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EH203_RS10535	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EH203_RS10540	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EH203_RS10545	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EH203_RS10550	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EH203_RS10555	COG2890	protein-(glutamine-N5) methyltransferase activity
EH203_RS10560	COG3094	Invasion gene expression up-regulator, SirB
EH203_RS10565	COG2912	Transglutaminase-like superfamily
EH203_RS10570	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EH203_RS10580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EH203_RS10585	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EH203_RS10595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH203_RS10600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EH203_RS10610	COG0673	inositol 2-dehydrogenase activity
EH203_RS10625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EH203_RS10665	COG4305	rare lipoprotein A
EH203_RS10670	COG1764	response to oxidative stress
EH203_RS10675	COG3783	Cytochrome b(562)
EH203_RS10685	COG0738	Major facilitator superfamily
EH203_RS10690	COG0456	acetyltransferase
EH203_RS10715	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EH203_RS10720	COG4628	conserved protein (DUF2132)
EH203_RS10740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EH203_RS10745	COG0076	glutamate decarboxylase activity
EH203_RS10750	COG1942	4-Oxalocrotonate Tautomerase
EH203_RS10775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EH203_RS10780	COG4221	oxidoreductase activity
EH203_RS10810	COG0477	Major facilitator Superfamily
EH203_RS10815	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EH203_RS10820	COG1940	carbohydrate kinase activity
EH203_RS10825	COG0583	DNA-binding transcription factor activity
EH203_RS10830	COG2814	Major facilitator Superfamily
EH203_RS10840	COG0114	fumarate hydratase activity
EH203_RS10845	COG1482	cell wall glycoprotein biosynthetic process
EH203_RS10850	COG5339	Protein conserved in bacteria
EH203_RS10860	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EH203_RS10870	COG0385	Bile acid
EH203_RS10875	COG0673	inositol 2-dehydrogenase activity
EH203_RS10885	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH203_RS10895	COG1879	ABC-type sugar transport system periplasmic component
EH203_RS10900	COG1069	ribulokinase activity
EH203_RS10905	COG2160	L-arabinose isomerase activity
EH203_RS10915	COG4657	Part of a membrane complex involved in electron transport
EH203_RS10920	COG2878	Part of a membrane complex involved in electron transport
EH203_RS10925	COG4656	Part of a membrane complex involved in electron transport
EH203_RS10930	COG4658	electron transport chain
EH203_RS10935	COG4659	FMN binding
EH203_RS10945	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EH203_RS10950	COG3104	oligopeptide transport
EH203_RS10960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EH203_RS10970	COG0616	signal peptide processing
EH203_RS10975	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS10980	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EH203_RS10985	COG1187	pseudouridine synthase activity
EH203_RS10990	COG0009	L-threonylcarbamoyladenylate synthase
EH203_RS10995	COG0613	PHP domain protein
EH203_RS11005	COG0512	Glutamine amidotransferase of anthranilate synthase
EH203_RS11010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EH203_RS11015	COG0135	phosphoribosylanthranilate isomerase activity
EH203_RS11015	COG0134	indole-3-glycerol-phosphate synthase activity
EH203_RS11020	COG0133	tryptophan synthase activity
EH203_RS11025	COG0159	tryptophan synthase activity
EH203_RS11030	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EH203_RS11035	COG3047	cAMP biosynthetic process
EH203_RS11045	COG2917	probably involved in intracellular septation
EH203_RS11050	COG1607	acyl-coa hydrolase
EH203_RS11060	COG2350	Protein conserved in bacteria
EH203_RS11075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH203_RS11080	COG3099	Belongs to the UPF0263 family
EH203_RS11090	COG0444	Belongs to the ABC transporter superfamily
EH203_RS11095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH203_RS11115	COG1454	alcohol dehydrogenase
EH203_RS11115	COG1012	belongs to the aldehyde dehydrogenase family
EH203_RS11120	COG1435	thymidine kinase activity
EH203_RS11135	COG0745	RESPONSE REGULATOR receiver
EH203_RS11140	COG1752	Esterase of the alpha-beta hydrolase superfamily
EH203_RS11145	COG3012	SEC-C Motif Domain Protein
EH203_RS11150	COG0788	formyltetrahydrofolate deformylase activity
EH203_RS11165	COG2860	membrane
EH203_RS11170	COG0708	Exodeoxyribonuclease III
EH203_RS11180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EH203_RS11185	COG0778	Nitroreductase
EH203_RS11190	COG0616	signal peptide processing
EH203_RS11195	COG0252	asparaginase activity
EH203_RS11200	COG1335	isochorismatase
EH203_RS11205	COG3139	Protein of unknown function (DUF1315)
EH203_RS11210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EH203_RS11225	COG0656	L-ascorbic acid biosynthetic process
EH203_RS11230	COG3713	MltA-interacting MipA family protein
EH203_RS11235	COG2766	serine protein kinase
EH203_RS11240	COG2718	Belongs to the UPF0229 family
EH203_RS11255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EH203_RS11260	COG0205	6-phosphofructokinase activity
EH203_RS11290	COG3684	Belongs to the aldolase LacD family
EH203_RS11295	COG2719	SpoVR family
EH203_RS11300	COG2186	Transcriptional regulator
EH203_RS11305	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EH203_RS11310	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EH203_RS11325	COG2983	Belongs to the UPF0260 family
EH203_RS11330	COG0179	Fumarylacetoacetate (FAA) hydrolase
EH203_RS11335	COG3100	YcgL domain-containing protein
EH203_RS11340	COG0850	regulation of cytokinetic process
EH203_RS11345	COG2894	cell division
EH203_RS11350	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EH203_RS11355	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EH203_RS11360	COG0318	PFAM AMP-dependent synthetase and ligase
EH203_RS11365	COG3065	identical protein binding
EH203_RS11375	COG1199	ATP-dependent helicase activity
EH203_RS11380	COG0251	oxidation-reduction process
EH203_RS11385	COG3140	Belongs to the UPF0181 family
EH203_RS11395	COG0494	nUDIX hydrolase
EH203_RS11400	COG1760	l-serine dehydratase
EH203_RS11405	COG1253	flavin adenine dinucleotide binding
EH203_RS11410	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH203_RS11410	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH203_RS11415	COG3715	PTS system
EH203_RS11420	COG3716	PTS system mannose fructose sorbose family IID component
EH203_RS11425	COG4811	Protein of unknown function (DUF986)
EH203_RS11430	COG1971	Probably functions as a manganese efflux pump
EH203_RS11435	COG2226	methyltransferase
EH203_RS11440	COG1278	Cold shock
EH203_RS11450	COG0803	Belongs to the bacterial solute-binding protein 9 family
EH203_RS11455	COG1121	(ABC) transporter
EH203_RS11460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH203_RS11465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH203_RS11480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH203_RS11485	COG1917	Cupin 2, conserved barrel domain protein
EH203_RS11495	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS11505	COG1175	transmembrane transport
EH203_RS11510	COG0395	ABC-type sugar transport system, permease component
EH203_RS11515	COG3842	ATPase activity
EH203_RS11525	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EH203_RS11530	COG2755	lipolytic protein G-D-S-L family
EH203_RS11530	COG0657	acetylesterase activity
EH203_RS11535	COG1988	membrane-bound metal-dependent
EH203_RS11545	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH203_RS11550	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EH203_RS11560	COG1132	(ABC) transporter
EH203_RS11570	COG0776	regulation of translation
EH203_RS11575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH203_RS11575	COG0072	phenylalanine-tRNA ligase activity
EH203_RS11580	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EH203_RS11590	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EH203_RS11595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EH203_RS11600	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EH203_RS11605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EH203_RS11610	COG1113	amino acid transport
EH203_RS11625	COG0823	Involved in the tonB-independent uptake of proteins
EH203_RS11630	COG0501	Belongs to the peptidase M48B family
EH203_RS11640	COG1653	transport
EH203_RS11645	COG2223	nitrite transmembrane transporter activity
EH203_RS11650	COG3279	Response regulator of the LytR AlgR family
EH203_RS11655	COG3275	phosphorelay sensor kinase activity
EH203_RS11660	COG5001	Diguanylate cyclase
EH203_RS11660	COG3300	MHYT domain
EH203_RS11680	COG0348	domain, Protein
EH203_RS11700	COG1187	pseudouridine synthase activity
EH203_RS11710	COG0482	sulfurtransferase activity
EH203_RS11715	COG2915	High frequency lysogenization protein hflD homolog
EH203_RS11720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EH203_RS11725	COG0745	RESPONSE REGULATOR receiver
EH203_RS11730	COG2205	protein histidine kinase activity
EH203_RS11735	COG2850	peptidyl-arginine hydroxylation
EH203_RS11740	COG2195	Cleaves the N-terminal amino acid of tripeptides
EH203_RS11745	COG3842	ATPase activity
EH203_RS11750	COG1176	ABC-type spermidine putrescine transport system, permease component I
EH203_RS11755	COG1177	transmembrane transport
EH203_RS11760	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EH203_RS11770	COG2207	Transcriptional regulator
EH203_RS11780	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EH203_RS11785	COG1956	GAF domain-containing protein
EH203_RS11790	COG2995	paraquat-inducible protein a
EH203_RS11795	COG3008	intermembrane lipid transfer
EH203_RS11800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EH203_RS11800	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EH203_RS11815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EH203_RS11825	COG1278	Cold shock
EH203_RS11835	COG1528	Iron-storage protein
EH203_RS11845	COG1770	oligopeptidase
EH203_RS11850	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EH203_RS11855	COG0800	Aldolase
EH203_RS11860	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EH203_RS11865	COG1737	Transcriptional regulator
EH203_RS11870	COG0469	pyruvate kinase activity
EH203_RS11875	COG1560	Kdo2-lipid A biosynthetic process
EH203_RS11880	COG0739	heme binding
EH203_RS11885	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EH203_RS11890	COG1121	(ABC) transporter
EH203_RS11895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH203_RS11900	COG1609	Transcriptional regulator
EH203_RS11905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH203_RS11910	COG1447	Phosphotransferase system cellobiose-specific component IIA
EH203_RS11915	COG4580	involved in the transport of maltose and maltodextrins
EH203_RS11920	COG2255	four-way junction helicase activity
EH203_RS11925	COG0632	four-way junction helicase activity
EH203_RS11930	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EH203_RS11935	COG0217	transcriptional regulatory protein
EH203_RS11940	COG0494	nUDIX hydrolase
EH203_RS11945	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EH203_RS11950	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EH203_RS11955	COG1801	Protein of unknown function DUF72
EH203_RS11960	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EH203_RS11965	COG2226	methyltransferase
EH203_RS11970	COG0500	methyltransferase
EH203_RS11975	COG3142	Participates in the control of copper homeostasis
EH203_RS11980	COG3102	Protein conserved in bacteria
EH203_RS11985	COG0018	arginyl-trna synthetase
EH203_RS11990	COG0728	peptidoglycan biosynthetic process
EH203_RS12000	COG3132	Protein of unknown function, DUF480
EH203_RS12005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH203_RS12010	COG0477	Major facilitator Superfamily
EH203_RS12015	COG2999	glutathione oxidoreductase activity
EH203_RS12025	COG3381	protein complex oligomerization
EH203_RS12030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EH203_RS12040	COG0840	transmembrane signaling receptor activity
EH203_RS12045	COG3130	regulation of translation
EH203_RS12050	COG3009	Protein conserved in bacteria
EH203_RS12060	COG2995	paraquat-inducible protein a
EH203_RS12065	COG0488	(ABC) transporter
EH203_RS12070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EH203_RS12070	COG0116	Belongs to the methyltransferase superfamily
EH203_RS12075	COG0633	Ferredoxin
EH203_RS12075	COG3217	Mosc domain protein beta barrel domain protein
EH203_RS12085	COG0167	dihydroorotate dehydrogenase activity
EH203_RS12090	COG0308	aminopeptidase N
EH203_RS12095	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EH203_RS12100	COG0017	Asparaginyl-tRNA synthetase
EH203_RS12110	COG1448	Aminotransferase
EH203_RS12115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EH203_RS12120	COG3108	Peptidase M15
EH203_RS12125	COG2989	Protein conserved in bacteria
EH203_RS12130	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EH203_RS12135	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EH203_RS12140	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EH203_RS12145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EH203_RS12155	COG3173	Aminoglycoside phosphotransferase
EH203_RS12165	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EH203_RS12170	COG2835	tetraacyldisaccharide 4'-kinase activity
EH203_RS12175	COG1663	tetraacyldisaccharide 4'-kinase activity
EH203_RS12180	COG1132	(ABC) transporter
EH203_RS12185	COG2333	competence protein COMEC
EH203_RS12185	COG0658	competence protein
EH203_RS12190	COG2926	Belongs to the UPF0265 family
EH203_RS12195	COG4604	ABC transporter, ATP-binding protein
EH203_RS12200	COG4605	iron ion homeostasis
EH203_RS12210	COG4607	ABC-type enterochelin transport system periplasmic component
EH203_RS12215	COG2925	Exonuclease
EH203_RS12220	COG0531	amino acid
EH203_RS12230	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EH203_RS12235	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EH203_RS12255	COG3052	prosthetic group binding
EH203_RS12260	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EH203_RS12265	COG0179	Fumarylacetoacetate (FAA) hydrolase
EH203_RS12270	COG3493	citrate carrier protein
EH203_RS12280	COG4565	transcriptional regulatory protein
EH203_RS12285	COG0840	transmembrane signaling receptor activity
EH203_RS12290	COG0840	transmembrane signaling receptor activity
EH203_RS12295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH203_RS12305	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EH203_RS12310	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EH203_RS12315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EH203_RS12320	COG0131	Imidazoleglycerol-phosphate dehydratase
EH203_RS12320	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EH203_RS12325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EH203_RS12330	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EH203_RS12335	COG0107	imidazoleglycerol-phosphate synthase activity
EH203_RS12340	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EH203_RS12340	COG0140	phosphoribosyl-ATP diphosphatase activity
EH203_RS12350	COG0776	regulation of translation
EH203_RS12355	COG0539	negative regulation of cytoplasmic translation
EH203_RS12360	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EH203_RS12365	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EH203_RS12370	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EH203_RS12375	COG1944	ATP diphosphatase activity
EH203_RS12380	COG2116	formate transmembrane transporter activity
EH203_RS12385	COG1882	Formate acetyltransferase
EH203_RS12390	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EH203_RS12415	COG2814	Major facilitator Superfamily
EH203_RS12420	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EH203_RS12425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EH203_RS12430	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EH203_RS12435	COG1674	ftsk spoiiie
EH203_RS12435	COG3107	peptidoglycan biosynthetic process
EH203_RS12445	COG0492	ferredoxin-NADP+ reductase activity
EH203_RS12450	COG4988	ABC transporter
EH203_RS12455	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EH203_RS12460	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EH203_RS12465	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EH203_RS12475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EH203_RS12480	COG0542	response to heat
EH203_RS12485	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EH203_RS12495	COG1278	Cold shock
EH203_RS12500	COG3593	DNA synthesis involved in DNA repair
EH203_RS12505	COG2431	L-lysine efflux transmembrane transporter activity
EH203_RS12510	COG1151	hydroxylamine reductase activity
EH203_RS12515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH203_RS12520	COG0702	epimerase
EH203_RS12525	COG3023	N-Acetylmuramoyl-L-alanine amidase
EH203_RS12530	COG0393	Putative heavy-metal-binding
EH203_RS12535	COG1126	abc transporter atp-binding protein
EH203_RS12540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH203_RS12545	COG4215	(ABC) transporter
EH203_RS12550	COG4160	amino acid transport
EH203_RS12555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH203_RS12560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EH203_RS12570	COG1177	transmembrane transport
EH203_RS12575	COG1176	ABC-type spermidine putrescine transport system, permease component I
EH203_RS12580	COG3842	ATPase activity
EH203_RS12585	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EH203_RS12595	COG0189	ligase activity
EH203_RS12600	COG0778	Nitroreductase
EH203_RS12605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EH203_RS12615	COG0569	domain protein
EH203_RS12615	COG2985	domain, Protein
EH203_RS12620	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EH203_RS12625	COG1349	DNA-binding transcription factor activity
EH203_RS12630	COG1686	Belongs to the peptidase S11 family
EH203_RS12635	COG2011	ABC-type metal ion transport system permease component
EH203_RS12640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EH203_RS12650	COG0625	glutathione transferase activity
EH203_RS12655	COG2133	pyrroloquinoline quinone binding
EH203_RS12660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH203_RS12665	COG2949	membrane
EH203_RS12670	COG2311	Membrane
EH203_RS12675	COG0302	gtp cyclohydrolase
EH203_RS12680	COG0840	transmembrane signaling receptor activity
EH203_RS12685	COG0583	DNA-binding transcription factor activity
EH203_RS12710	COG0371	Dehydrogenase
EH203_RS12715	COG1129	ABC transporter
EH203_RS12720	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH203_RS12725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH203_RS12730	COG4771	TonB-dependent receptor
EH203_RS12735	COG0833	amino acid
EH203_RS12740	COG0583	DNA-binding transcription factor activity
EH203_RS12745	COG2855	membrane
EH203_RS12755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH203_RS12755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH203_RS12755	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EH203_RS12760	COG1105	Belongs to the carbohydrate kinase PfkB family
EH203_RS12765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH203_RS12765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH203_RS12780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EH203_RS12785	COG0523	cobalamin synthesis protein
EH203_RS12790	COG0671	phosphoesterase, PA-phosphatase related
EH203_RS12795	COG0791	NLP P60 protein
EH203_RS12810	COG0625	glutathione transferase activity
EH203_RS12820	COG4166	transmembrane transport
EH203_RS12825	COG4174	ABC transporter (Permease)
EH203_RS12830	COG4239	(ABC) transporter, permease
EH203_RS12835	COG4172	Belongs to the ABC transporter superfamily
EH203_RS12845	COG2814	Major facilitator Superfamily
EH203_RS12850	COG1187	pseudouridine synthase activity
EH203_RS12860	COG1061	Type III restriction enzyme res subunit
EH203_RS12865	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EH203_RS12875	COG3081	Nucleoid-associated protein
EH203_RS12880	COG3082	Protein of unknown function (DUF1414)
EH203_RS12885	COG3083	sulfuric ester hydrolase activity
EH203_RS12895	COG0582	viral genome integration into host DNA
EH203_RS12930	COG3077	Addiction module antitoxin, RelB DinJ family
EH203_RS12960	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EH203_RS12975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH203_RS12980	COG0534	Mate efflux family protein
EH203_RS12985	COG2807	transmembrane transport
EH203_RS12990	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EH203_RS13000	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EH203_RS13005	COG0783	Belongs to the Dps family
EH203_RS13010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH203_RS13015	COG0765	amino acid transport
EH203_RS13020	COG1126	abc transporter atp-binding protein
EH203_RS13030	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EH203_RS13190	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EH203_RS13205	COG1686	Belongs to the peptidase S11 family
EH203_RS13230	COG2040	homocysteine
EH203_RS13235	COG0833	amino acid
EH203_RS13240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EH203_RS13245	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EH203_RS13250	COG0747	negative chemotaxis
EH203_RS13255	COG2195	Cleaves the N-terminal amino acid of tripeptides
EH203_RS13260	COG3708	Transcriptional regulator
EH203_RS13260	COG2207	Transcriptional regulator
EH203_RS13270	COG0513	Belongs to the DEAD box helicase family
EH203_RS13280	COG1120	ATPase activity
EH203_RS13285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH203_RS13290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH203_RS13295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH203_RS13310	COG1131	(ABC) transporter
EH203_RS13315	COG0842	Transport permease protein
EH203_RS13320	COG0842	Transport permease protein
EH203_RS13325	COG0670	Belongs to the BI1 family
EH203_RS13330	COG0314	molybdopterin synthase activity
EH203_RS13335	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EH203_RS13340	COG0315	cyclic pyranopterin monophosphate synthase activity
EH203_RS13345	COG0521	Mo-molybdopterin cofactor biosynthetic process
EH203_RS13350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EH203_RS13365	COG0556	nucleotide-excision repair
EH203_RS13385	COG3157	Type VI secretion system effector, Hcp
EH203_RS13390	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EH203_RS13395	COG2226	methyltransferase
EH203_RS13400	COG0156	8-amino-7-oxononanoate synthase activity
EH203_RS13405	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EH203_RS13415	COG5297	Belongs to the glycosyl hydrolase family 6
EH203_RS13420	COG1380	Effector of murein hydrolase LrgA
EH203_RS13425	COG1346	cytolysis
EH203_RS13430	COG0295	cytidine deaminase activity
EH203_RS13435	COG0281	malic enzyme
EH203_RS13440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH203_RS13445	COG0601	transmembrane transport
EH203_RS13450	COG0747	negative chemotaxis
EH203_RS13455	COG4172	Belongs to the ABC transporter superfamily
EH203_RS13460	COG0303	'Molybdopterin
EH203_RS13465	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EH203_RS13480	COG3706	GGDEF domain
EH203_RS13500	COG0401	homolog of Blt101
EH203_RS13525	COG3228	Belongs to the MtfA family
EH203_RS13540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EH203_RS13565	COG5002	protein histidine kinase activity
EH203_RS13575	COG1073	alpha beta
EH203_RS13595	COG0667	Aldo Keto reductase
EH203_RS13600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EH203_RS13610	COG2207	Transcriptional regulator
EH203_RS13660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EH203_RS13675	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EH203_RS13685	COG2199	diguanylate cyclase activity
EH203_RS13700	COG3122	Protein conserved in bacteria
EH203_RS13710	COG2723	6-phospho-beta-galactosidase activity
EH203_RS13725	COG2814	Major facilitator Superfamily
EH203_RS13745	COG1733	regulation of RNA biosynthetic process
EH203_RS13750	COG0640	Transcriptional regulator
EH203_RS13755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EH203_RS13765	COG1733	regulation of RNA biosynthetic process
EH203_RS13770	COG2910	NAD(P)H-binding
EH203_RS13775	COG0625	glutathione transferase activity
EH203_RS13780	COG0784	Response regulator, receiver
EH203_RS13780	COG0835	chemotaxis
EH203_RS13795	COG2995	paraquat-inducible protein a
EH203_RS13800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EH203_RS13800	COG3008	intermembrane lipid transfer
EH203_RS13820	COG1132	(ABC) transporter
EH203_RS13840	COG4771	TonB-dependent receptor
EH203_RS13860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH203_RS13880	COG4172	Belongs to the ABC transporter superfamily
EH203_RS13895	COG0747	negative chemotaxis
EH203_RS13900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH203_RS13930	COG2226	methyltransferase
EH203_RS13935	COG0840	transmembrane signaling receptor activity
EH203_RS13940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EH203_RS13945	COG1012	belongs to the aldehyde dehydrogenase family
EH203_RS13985	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EH203_RS13995	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EH203_RS14000	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EH203_RS14005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH203_RS14030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH203_RS14035	COG0371	Dehydrogenase
EH203_RS14040	COG1301	dicarboxylic acid transport
EH203_RS14060	COG0697	spore germination
EH203_RS14065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EH203_RS14070	COG1136	(ABC) transporter
EH203_RS14070	COG0577	efflux transmembrane transporter activity
EH203_RS14080	COG0577	efflux transmembrane transporter activity
EH203_RS14080	COG1136	(ABC) transporter
EH203_RS14095	COG0672	)-iron permease
EH203_RS14100	COG0840	transmembrane signaling receptor activity
EH203_RS14105	COG3383	formate dehydrogenase (NAD+) activity
EH203_RS14110	COG2851	Citrate transporter
EH203_RS14120	COG1301	dicarboxylic acid transport
EH203_RS14125	COG0583	DNA-binding transcription factor activity
EH203_RS14140	COG1464	Belongs to the NlpA lipoprotein family
EH203_RS14155	COG2271	Major facilitator Superfamily
EH203_RS14160	COG1840	ABC-type Fe3 transport system, periplasmic component
EH203_RS14170	COG3842	ATPase activity
EH203_RS14175	COG1609	Transcriptional regulator
EH203_RS14180	COG3250	beta-galactosidase activity
EH203_RS14185	COG2223	nitrite transmembrane transporter activity
EH203_RS14195	COG0604	alcohol dehydrogenase
EH203_RS14200	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS14210	COG1902	pentaerythritol trinitrate reductase activity
EH203_RS14220	COG0596	Alpha beta hydrolase
EH203_RS14225	COG0583	DNA-binding transcription factor activity
EH203_RS14235	COG3615	Tellurite resistance protein tehB
EH203_RS14245	COG2203	Gaf domain
EH203_RS14245	COG2199	diguanylate cyclase activity
EH203_RS14250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH203_RS14250	COG2190	(PTS) system
EH203_RS14250	COG1263	PTS System
EH203_RS14255	COG2723	6-phospho-beta-galactosidase activity
EH203_RS14265	COG1840	ABC-type Fe3 transport system, periplasmic component
EH203_RS14270	COG4208	sulfate ABC transporter
EH203_RS14275	COG3842	ATPase activity
EH203_RS14290	COG3718	enzyme involved in inositol metabolism
EH203_RS14300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH203_RS14310	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH203_RS14320	COG1879	ABC-type sugar transport system periplasmic component
EH203_RS14325	COG0673	inositol 2-dehydrogenase activity
EH203_RS14330	COG3962	Belongs to the TPP enzyme family
EH203_RS14360	COG3706	GGDEF domain
EH203_RS14365	COG3711	transcriptional antiterminator
EH203_RS14370	COG2723	6-phospho-beta-galactosidase activity
EH203_RS14380	COG1605	Chorismate mutase
EH203_RS14385	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH203_RS14410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EH203_RS14420	COG1215	transferase activity, transferring glycosyl groups
EH203_RS14430	COG1051	belongs to the nudix hydrolase family
EH203_RS14435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH203_RS14440	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EH203_RS14470	COG0463	Glycosyl transferase, family 2
EH203_RS14470	COG1216	Glycosyl transferase, family 2
EH203_RS14475	COG2244	polysaccharide biosynthetic process
EH203_RS14485	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EH203_RS14495	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EH203_RS14515	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH203_RS14520	COG1253	flavin adenine dinucleotide binding
EH203_RS14540	COG2982	Protein involved in outer membrane biogenesis
EH203_RS14545	COG0717	Belongs to the dCTP deaminase family
EH203_RS14550	COG0572	uridine kinase
EH203_RS14555	COG0489	protein tyrosine kinase activity
EH203_RS14560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH203_RS14560	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH203_RS14570	COG0437	4 iron, 4 sulfur cluster binding
EH203_RS14575	COG2864	formate dehydrogenase
EH203_RS14590	COG2706	6-phosphogluconolactonase activity
EH203_RS14735	COG1783	phage Terminase large subunit
EH203_RS14830	COG0305	Participates in initiation and elongation during chromosome replication
EH203_RS14900	COG0561	phosphatase activity
EH203_RS14905	COG0837	glucose binding
EH203_RS14910	COG2211	Major facilitator Superfamily
EH203_RS14935	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EH203_RS14940	COG4149	molybdate abc transporter
EH203_RS14945	COG0725	ABC transporter, periplasmic molybdate-binding protein
EH203_RS14955	COG3585	molybdate ion transport
EH203_RS14955	COG2005	Transcriptional regulator
EH203_RS14960	COG1119	ATPase activity
EH203_RS14965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EH203_RS14970	COG2017	converts alpha-aldose to the beta-anomer
EH203_RS14990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH203_RS14995	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH203_RS15000	COG0588	phosphoglycerate mutase activity
EH203_RS15005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EH203_RS15010	COG1230	cation diffusion facilitator family transporter
EH203_RS15020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EH203_RS15030	COG1811	Na channel or pump
EH203_RS15050	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EH203_RS15055	COG2885	chlorophyll binding
EH203_RS15060	COG0823	Involved in the tonB-independent uptake of proteins
EH203_RS15065	COG3064	Membrane
EH203_RS15070	COG0848	biopolymer transport protein
EH203_RS15075	COG0811	peptide transport
EH203_RS15080	COG0824	Thioesterase
EH203_RS15085	COG3790	cyd operon protein YbgE
EH203_RS15090	COG4890	Cyd operon protein YbgT
EH203_RS15095	COG1294	oxidase, subunit
EH203_RS15100	COG1271	oxidase subunit
EH203_RS15110	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EH203_RS15115	COG0045	succinate-CoA ligase (ADP-forming) activity
EH203_RS15120	COG0508	dehydrogenase complex catalyzes the overall conversion of
EH203_RS15125	COG0567	Dehydrogenase, E1 component
EH203_RS15130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EH203_RS15135	COG1053	succinate dehydrogenase
EH203_RS15140	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EH203_RS15145	COG2009	succinate dehydrogenase
EH203_RS15160	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EH203_RS15165	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EH203_RS15170	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EH203_RS15175	COG1984	allophanate hydrolase subunit 2
EH203_RS15180	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EH203_RS15185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EH203_RS15190	COG0415	Belongs to the DNA photolyase family
EH203_RS15195	COG3272	Protein of unknown function (DUF1722)
EH203_RS15200	COG3842	ATPase activity
EH203_RS15205	COG1840	ABC-type Fe3 transport system, periplasmic component
EH203_RS15225	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EH203_RS15230	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EH203_RS15235	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EH203_RS15240	COG2205	protein histidine kinase activity
EH203_RS15245	COG0745	RESPONSE REGULATOR receiver
EH203_RS15255	COG0033	Phosphoglucomutase
EH203_RS15260	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EH203_RS15265	COG0596	Alpha beta hydrolase
EH203_RS15275	COG0840	transmembrane signaling receptor activity
EH203_RS15280	COG0716	FMN binding
EH203_RS15285	COG0735	belongs to the Fur family
EH203_RS15290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH203_RS15295	COG1263	PTS System
EH203_RS15295	COG2190	(PTS) system
EH203_RS15295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH203_RS15300	COG0363	glucosamine-6-phosphate deaminase activity
EH203_RS15305	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EH203_RS15310	COG1846	Transcriptional regulator
EH203_RS15310	COG1940	carbohydrate kinase activity
EH203_RS15315	COG0367	asparagine synthase
EH203_RS15355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH203_RS15360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH203_RS15365	COG1702	phosphate starvation-inducible protein PhoH
EH203_RS15370	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EH203_RS15375	COG4535	Mg2 and Co2 transporter CorC
EH203_RS15380	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EH203_RS15390	COG0765	amino acid transport
EH203_RS15395	COG0765	amino acid transport
EH203_RS15400	COG1126	abc transporter atp-binding protein
EH203_RS15405	COG2888	peptidyl-tyrosine sulfation
EH203_RS15410	COG0495	leucyl-tRNA aminoacylation
EH203_RS15415	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EH203_RS15420	COG1466	dna polymerase III delta subunit
EH203_RS15425	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EH203_RS15430	COG0799	negative regulation of ribosome biogenesis
EH203_RS15435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EH203_RS15445	COG0772	Belongs to the SEDS family
EH203_RS15450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EH203_RS15455	COG1686	Belongs to the peptidase S11 family
EH203_RS15460	COG2921	Belongs to the UPF0250 family
EH203_RS15465	COG0321	lipoyl(octanoyl) transferase activity
EH203_RS15470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EH203_RS15475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EH203_RS15480	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EH203_RS15485	COG1278	Cold shock
EH203_RS15490	COG1794	racemase activity, acting on amino acids and derivatives
EH203_RS15500	COG1393	Belongs to the ArsC family
EH203_RS15505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EH203_RS15510	COG1876	peptidase activity
EH203_RS15525	COG0400	carboxylic ester hydrolase activity
EH203_RS15530	COG3813	Protein conserved in bacteria
EH203_RS15545	COG4178	(ABC) transporter
EH203_RS15560	COG1595	DNA-templated transcription, initiation
EH203_RS15565	COG3712	iron ion homeostasis
EH203_RS15570	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EH203_RS15585	COG3118	belongs to the thioredoxin family
EH203_RS15595	COG1444	tRNA N-acetyltransferase activity
EH203_RS15600	COG2707	UPF0756 membrane protein
EH203_RS15605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EH203_RS15610	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EH203_RS15620	COG2716	regulation of RNA biosynthetic process
EH203_RS15625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EH203_RS15640	COG4783	chaperone-mediated protein folding
EH203_RS15645	COG1393	Belongs to the ArsC family
EH203_RS15650	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EH203_RS15655	COG2233	PERMEase
EH203_RS15660	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EH203_RS15665	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EH203_RS15670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EH203_RS15685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH203_RS15690	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EH203_RS15695	COG4181	ATPase activity
EH203_RS15700	COG2755	lipolytic protein G-D-S-L family
EH203_RS15705	COG0300	oxidoreductase activity
EH203_RS15710	COG3118	belongs to the thioredoxin family
EH203_RS15720	COG0814	amino acid
EH203_RS15740	COG1441	menaquinone biosynthetic process
EH203_RS15745	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EH203_RS15750	COG0596	Alpha beta hydrolase
EH203_RS15755	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EH203_RS15760	COG1169	isochorismate synthase
EH203_RS15765	COG2223	nitrite transmembrane transporter activity
EH203_RS15770	COG0642	Histidine kinase
EH203_RS15770	COG2198	Histidine kinase
EH203_RS15775	COG2197	response regulator
EH203_RS15780	COG2205	protein histidine kinase activity
EH203_RS15780	COG0784	Response regulator, receiver
EH203_RS15790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EH203_RS15795	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EH203_RS15800	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EH203_RS15805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH203_RS15810	COG0330	HflC and HflK could
EH203_RS15815	COG1585	Membrane protein implicated in regulation of membrane protease activity
EH203_RS15825	COG2217	Heavy metal translocating P-type atpase
EH203_RS15830	COG3735	TraB family
EH203_RS15840	COG5434	Belongs to the glycosyl hydrolase 28 family
EH203_RS15845	COG0523	cobalamin synthesis protein
EH203_RS15850	COG2879	small protein
EH203_RS15855	COG1966	Carbon starvation protein
EH203_RS15870	COG0737	Belongs to the 5'-nucleotidase family
EH203_RS15875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EH203_RS15875	COG4651	solute:proton antiporter activity
EH203_RS15880	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH203_RS15885	COG0563	adenylate kinase activity
EH203_RS15890	COG0326	Molecular chaperone. Has ATPase activity
EH203_RS15895	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EH203_RS15900	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EH203_RS15910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EH203_RS15915	COG2832	Protein of unknown function (DUF454)
EH203_RS15930	COG1309	transcriptional regulator
EH203_RS15935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH203_RS15940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH203_RS15945	COG0254	rRNA binding
EH203_RS15950	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EH203_RS15970	COG3695	enzyme binding
EH203_RS15975	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EH203_RS15980	COG1946	Acyl-CoA thioesterase
EH203_RS15985	COG0004	ammonium transporteR
EH203_RS15990	COG0347	Belongs to the P(II) protein family
EH203_RS15995	COG1132	(ABC) transporter
EH203_RS16000	COG1132	(ABC) transporter
EH203_RS16005	COG1522	sequence-specific DNA binding
EH203_RS16010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH203_RS16015	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EH203_RS16020	COG0824	Thioesterase
EH203_RS16025	COG1555	photosystem II stabilization
EH203_RS16030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH203_RS16035	COG0776	regulation of translation
EH203_RS16040	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EH203_RS16045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EH203_RS16055	COG0544	peptidyl-prolyl cis-trans isomerase activity
EH203_RS16060	COG0271	Belongs to the BolA IbaG family
EH203_RS16065	COG3056	Lipoprotein
EH203_RS16075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EH203_RS16080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EH203_RS16085	COG1845	cytochrome c oxidase, subunit III
EH203_RS16090	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EH203_RS16095	COG0109	protoheme IX farnesyltransferase activity
EH203_RS16100	COG2814	Major facilitator Superfamily
EH203_RS16105	COG1666	GTP binding
EH203_RS16110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EH203_RS16115	COG0693	protein deglycase activity
EH203_RS16120	COG0301	tRNA thio-modification
EH203_RS16120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH203_RS16125	COG1722	exodeoxyribonuclease VII activity
EH203_RS16130	COG0142	geranyltranstransferase activity
EH203_RS16135	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EH203_RS16140	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EH203_RS16145	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EH203_RS16150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EH203_RS16155	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EH203_RS16160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EH203_RS16160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EH203_RS16165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EH203_RS16170	COG4238	major outer membrane lipoprotein
EH203_RS16175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EH203_RS16180	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EH203_RS16185	COG1862	Preprotein translocase
EH203_RS16190	COG0343	queuine tRNA-ribosyltransferase activity
EH203_RS16195	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EH203_RS16200	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EH203_RS16205	COG0450	alkyl hydroperoxide reductase
EH203_RS16210	COG0668	transmembrane transport
EH203_RS16220	COG1114	Component of the transport system for branched-chain amino acids
EH203_RS16225	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EH203_RS16245	COG0420	3'-5' exonuclease activity
EH203_RS16250	COG0419	ATPase involved in DNA repair
EH203_RS16255	COG1940	carbohydrate kinase activity
EH203_RS16260	COG2974	May be involved in recombination
EH203_RS16270	COG2188	Transcriptional regulator
EH203_RS16275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH203_RS16280	COG1397	ADP-ribosylglycohydrolase
EH203_RS16285	COG2211	Major facilitator Superfamily
EH203_RS16290	COG3123	guanosine phosphorylase activity
EH203_RS16295	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EH203_RS16305	COG4615	Cyclic peptide transporter
EH203_RS16335	COG5297	Belongs to the glycosyl hydrolase family 6
EH203_RS16340	COG1312	Catalyzes the dehydration of D-mannonate
EH203_RS16345	COG2186	Transcriptional regulator
EH203_RS16385	COG2951	lytic endotransglycosylase activity
EH203_RS16390	COG2824	Alkylphosphonate utilization operon protein PhnA
EH203_RS16395	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EH203_RS16420	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EH203_RS16425	COG3015	lipoprotein NlpE involved in copper resistance
EH203_RS16430	COG4681	YaeQ
EH203_RS16440	COG4568	rho-dependent transcription termination
EH203_RS16445	COG0037	tRNA processing
EH203_RS16450	COG0346	lactoylglutathione lyase activity
EH203_RS16455	COG0825	malonyl-CoA metabolic process
EH203_RS16460	COG0587	DNA-directed DNA polymerase activity
EH203_RS16465	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EH203_RS16470	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH203_RS16475	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH203_RS16480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EH203_RS16485	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH203_RS16490	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EH203_RS16495	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH203_RS16500	COG0750	zinc metalloprotease
EH203_RS16505	COG0575	Belongs to the CDS family
EH203_RS16510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EH203_RS16515	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EH203_RS16520	COG0233	cytoplasmic translational termination
EH203_RS16525	COG0528	UMP kinase activity
EH203_RS16530	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EH203_RS16535	COG0052	Belongs to the universal ribosomal protein uS2 family
EH203_RS16540	COG0024	Methionine aminopeptidase
EH203_RS16545	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EH203_RS16550	COG2171	N-acyltransferase activity
EH203_RS16590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EH203_RS16590	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EH203_RS16595	COG1611	Belongs to the LOG family
EH203_RS16600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH203_RS16605	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EH203_RS16610	COG2363	Small membrane protein
EH203_RS16615	COG0583	DNA-binding transcription factor activity
EH203_RS16625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH203_RS16630	COG2166	iron-sulfur cluster assembly
EH203_RS16635	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EH203_RS16645	COG0747	negative chemotaxis
EH203_RS16655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH203_RS16660	COG4172	Belongs to the ABC transporter superfamily
EH203_RS16665	COG1473	amidohydrolase
EH203_RS16675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EH203_RS16680	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EH203_RS16700	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH203_RS16705	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EH203_RS16705	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EH203_RS16715	COG1609	Transcriptional regulator
EH203_RS16720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EH203_RS16725	COG1074	ATP-dependent DNA helicase activity
EH203_RS16730	COG1025	Belongs to the peptidase M16 family
EH203_RS16735	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EH203_RS16750	COG4795	General secretion pathway protein
EH203_RS16770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EH203_RS16775	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EH203_RS16790	COG3066	DNA modification
EH203_RS16795	COG0861	Integral membrane protein TerC family
EH203_RS16805	COG0667	Aldo Keto reductase
EH203_RS16815	COG3171	Protein conserved in bacteria
EH203_RS16820	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EH203_RS16830	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EH203_RS16835	COG0741	lytic transglycosylase activity
EH203_RS16840	COG1917	Cupin 2, conserved barrel domain protein
EH203_RS16840	COG2169	Transcriptional regulator
EH203_RS16850	COG5564	TIM-barrel signal transduction protein
EH203_RS16855	COG5441	Belongs to the UPF0261 family
EH203_RS16875	COG1113	amino acid transport
EH203_RS16880	COG1982	Orn Lys Arg decarboxylase major
EH203_RS16890	COG3423	Transcriptional regulator
EH203_RS16900	COG1045	serine acetyltransferase
EH203_RS16920	COG0297	glycogen (starch) synthase activity
EH203_RS16975	COG2814	Major facilitator Superfamily
EH203_RS16980	COG1846	Transcriptional regulator
EH203_RS16995	COG2249	NAD(P)H dehydrogenase (quinone) activity
EH203_RS17060	COG3121	Chaperone
EH203_RS17075	COG1129	ABC transporter
EH203_RS17085	COG4948	Mandelate Racemase Muconate Lactonizing
EH203_RS17090	COG4773	Receptor
EH203_RS17100	COG0583	DNA-binding transcription factor activity
EH203_RS17145	COG0811	peptide transport
EH203_RS17160	COG1802	Transcriptional regulator
EH203_RS17165	COG0246	Mannitol dehydrogenase
EH203_RS17170	COG0477	Major facilitator Superfamily
EH203_RS17175	COG1063	alcohol dehydrogenase
EH203_RS17180	COG4948	Mandelate Racemase Muconate Lactonizing
EH203_RS17185	COG0583	DNA-binding transcription factor activity
EH203_RS17195	COG0437	4 iron, 4 sulfur cluster binding
EH203_RS17200	COG3301	Polysulphide reductase, NrfD
EH203_RS17205	COG0477	Major facilitator Superfamily
EH203_RS17210	COG3976	FMN-binding domain protein
EH203_RS17210	COG1053	succinate dehydrogenase
EH203_RS17210	COG0431	NADPH-dependent FMN reductase
EH203_RS17215	COG1053	succinate dehydrogenase
EH203_RS17225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EH203_RS17225	COG2169	Transcriptional regulator
EH203_RS17250	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EH203_RS17250	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EH203_RS17255	COG3604	Transcriptional regulator
EH203_RS17260	COG1773	rubredoxin
EH203_RS17260	COG0426	domain, Protein
EH203_RS17265	COG0446	pyridine nucleotide-disulphide oxidoreductase
EH203_RS17275	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EH203_RS17285	COG0531	amino acid
EH203_RS17290	COG3115	cell septum assembly
EH203_RS17295	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EH203_RS17300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH203_RS17305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH203_RS17315	COG2190	(PTS) system
EH203_RS17320	COG2205	protein histidine kinase activity
EH203_RS17325	COG0745	RESPONSE REGULATOR receiver
EH203_RS17330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH203_RS17335	COG0577	efflux transmembrane transporter activity
EH203_RS17335	COG1136	(ABC) transporter
EH203_RS17340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH203_RS17345	COG4208	sulfate ABC transporter
EH203_RS17350	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EH203_RS17355	COG4150	thiosulfate binding
EH203_RS17360	COG2837	iron assimilation
EH203_RS17370	COG4178	(ABC) transporter
EH203_RS17375	COG0612	Peptidase, M16
EH203_RS17390	COG0456	acetyltransferase
EH203_RS17395	COG0408	coproporphyrinogen oxidase activity
EH203_RS17400	COG1671	Belongs to the UPF0178 family
EH203_RS17405	COG0814	amino acid
EH203_RS17420	COG2084	Dehydrogenase
EH203_RS17425	COG1082	Xylose isomerase domain protein TIM barrel
EH203_RS17430	COG0149	triose-phosphate isomerase activity
EH203_RS17435	COG2376	Dihydroxyacetone kinase
EH203_RS17445	COG0698	ribose 5-phosphate isomerase
EH203_RS17450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EH203_RS17455	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EH203_RS17460	COG2190	(PTS) system
EH203_RS17460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH203_RS17460	COG1263	PTS System
EH203_RS17465	COG2723	6-phospho-beta-galactosidase activity
EH203_RS17470	COG3711	transcriptional antiterminator
EH203_RS17480	COG0765	amino acid transport
EH203_RS17485	COG1126	abc transporter atp-binding protein
EH203_RS17490	COG1609	Transcriptional regulator
EH203_RS17520	COG0494	nUDIX hydrolase
EH203_RS17525	COG0477	Major facilitator Superfamily
EH203_RS17530	COG1942	4-Oxalocrotonate Tautomerase
EH203_RS17535	COG1914	H( )-stimulated, divalent metal cation uptake system
EH203_RS17540	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EH203_RS17545	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EH203_RS17550	COG0497	DNA recombination
EH203_RS17560	COG2914	Belongs to the UPF0125 (RnfH) family
EH203_RS17565	COG2867	negative regulation of translational initiation
EH203_RS17570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EH203_RS17580	COG0582	viral genome integration into host DNA
EH203_RS17585	COG3012	SEC-C Motif Domain Protein
EH203_RS17635	COG2026	Addiction module toxin, RelE StbE family
EH203_RS17660	COG1280	lysine exporter protein (LysE YggA)
EH203_RS17680	COG3038	cytochrome b561
EH203_RS17685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EH203_RS17690	COG1376	ErfK ybiS ycfS ynhG family protein
EH203_RS17695	COG2873	o-acetylhomoserine
EH203_RS17700	COG0246	Mannitol dehydrogenase
EH203_RS17720	COG3712	iron ion homeostasis
EH203_RS17740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EH203_RS17745	COG3162	membrane
EH203_RS17750	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EH203_RS17840	COG4964	Belongs to the GSP D family
EH203_RS17860	COG5002	protein histidine kinase activity
EH203_RS17860	COG3850	Histidine kinase
EH203_RS17870	COG0025	NhaP-type Na H and K H
EH203_RS17875	COG2252	PERMEase
EH203_RS17900	COG1953	Uracil, thiamine, allantoin
EH203_RS17905	COG1560	Kdo2-lipid A biosynthetic process
EH203_RS17915	COG4319	ketosteroid isomerase
EH203_RS17970	COG2207	Transcriptional regulator
EH203_RS17975	COG1733	regulation of RNA biosynthetic process
EH203_RS17990	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EH203_RS18000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EH203_RS18005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EH203_RS18010	COG4974	Belongs to the 'phage' integrase family
EH203_RS18015	COG0477	Major facilitator Superfamily
EH203_RS18025	COG0716	FMN binding
EH203_RS18035	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EH203_RS18045	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EH203_RS18050	COG0354	folic acid binding
EH203_RS18055	COG1272	protein, Hemolysin III
EH203_RS18075	COG2211	Major facilitator Superfamily
EH203_RS18080	COG1653	transport
EH203_RS18085	COG3842	ATPase activity
EH203_RS18090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EH203_RS18100	COG1175	transmembrane transport
EH203_RS18105	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS18110	COG1733	regulation of RNA biosynthetic process
EH203_RS18115	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EH203_RS18115	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EH203_RS18120	COG0509	glycine decarboxylation via glycine cleavage system
EH203_RS18125	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EH203_RS18130	COG1454	alcohol dehydrogenase
EH203_RS18195	COG0656	L-ascorbic acid biosynthetic process
EH203_RS18200	COG2813	Specifically methylates the guanine in position
EH203_RS18205	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EH203_RS18210	COG0456	acetyltransferase
EH203_RS18220	COG1595	DNA-templated transcription, initiation
EH203_RS18225	COG3712	iron ion homeostasis
EH203_RS18235	COG4178	(ABC) transporter
EH203_RS18240	COG0813	purine-nucleoside phosphorylase activity
EH203_RS18245	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EH203_RS18250	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EH203_RS18255	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EH203_RS18265	COG2827	Endonuclease containing a URI domain
EH203_RS18270	COG3153	acetyltransferase
EH203_RS18290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH203_RS18295	COG0513	Belongs to the DEAD box helicase family
EH203_RS18310	COG1185	polyribonucleotide nucleotidyltransferase activity
EH203_RS18315	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EH203_RS18320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EH203_RS18325	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EH203_RS18330	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EH203_RS18340	COG0779	Required for maturation of 30S ribosomal subunits
EH203_RS18350	COG2197	response regulator
EH203_RS18400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH203_RS18410	COG2130	NADP-dependent
EH203_RS18420	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EH203_RS18425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EH203_RS18430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EH203_RS18435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH203_RS18440	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EH203_RS18445	COG1534	Rna-binding protein
EH203_RS18450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EH203_RS18455	COG2027	D-alanyl-D-alanine carboxypeptidase
EH203_RS18460	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EH203_RS18465	COG0697	spore germination
EH203_RS18470	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EH203_RS18475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EH203_RS18480	COG0142	geranyltranstransferase activity
EH203_RS18500	COG0039	L-malate dehydrogenase activity
EH203_RS18505	COG1438	arginine binding
EH203_RS18510	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EH203_RS18520	COG0358	DNA primase activity
EH203_RS18525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH203_RS18530	COG3663	DNA glycosylase
EH203_RS18540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EH203_RS18540	COG2755	lipolytic protein G-D-S-L family
EH203_RS18545	COG0583	DNA-binding transcription factor activity
EH203_RS18570	COG2199	diguanylate cyclase activity
EH203_RS18575	COG3678	ATP-independent chaperone mediated protein folding
EH203_RS18585	COG1902	pentaerythritol trinitrate reductase activity
EH203_RS18585	COG0446	pyridine nucleotide-disulphide oxidoreductase
EH203_RS18590	COG2813	Specifically methylates the guanine in position
EH203_RS18595	COG0673	inositol 2-dehydrogenase activity
EH203_RS18600	COG0861	Integral membrane protein TerC family
EH203_RS18605	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EH203_RS18615	COG2721	sulfolactate sulfo-lyase activity
EH203_RS18620	COG0246	Mannitol dehydrogenase
EH203_RS18625	COG1904	glucuronate isomerase
EH203_RS18630	COG2271	Major facilitator Superfamily
EH203_RS18640	COG0586	Pfam SNARE associated Golgi protein
EH203_RS18650	COG1422	Protein of unknown function (DUF1090)
EH203_RS18655	COG4575	ribosome binding
EH203_RS18660	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EH203_RS18670	COG2259	Doxx family
EH203_RS18675	COG0435	Glutathione S-transferase
EH203_RS18680	COG0583	DNA-binding transcription factor activity
EH203_RS18685	COG1741	Belongs to the pirin family
EH203_RS18690	COG0735	belongs to the Fur family
EH203_RS18700	COG3237	CsbD-like
EH203_RS18710	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EH203_RS18715	COG2937	Belongs to the GPAT DAPAT family
EH203_RS18720	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EH203_RS18725	COG3161	chorismate lyase activity
EH203_RS18730	COG0459	protein refolding
EH203_RS18735	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EH203_RS18750	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EH203_RS18755	COG1324	tolerance protein
EH203_RS18760	COG4232	protein-disulfide reductase activity
EH203_RS18765	COG1309	transcriptional regulator
EH203_RS18785	COG0582	viral genome integration into host DNA
EH203_RS18790	COG3423	Transcriptional regulator
EH203_RS18805	COG1404	Belongs to the peptidase S8 family
EH203_RS18810	COG2255	four-way junction helicase activity
EH203_RS18840	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EH203_RS18845	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EH203_RS18855	COG4778	phosphonate C-P lyase system protein PhnL
EH203_RS18895	COG0300	oxidoreductase activity
EH203_RS18895	COG0318	PFAM AMP-dependent synthetase and ligase
EH203_RS18895	COG3321	synthase
EH203_RS18895	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS18895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH203_RS18905	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS18910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH203_RS18915	COG3433	isochorismatase activity
EH203_RS18915	COG1535	isochorismatase
EH203_RS18920	COG1021	2,3-dihydroxybenzoate-AMP ligase
EH203_RS18925	COG1169	isochorismate synthase
EH203_RS18935	COG4771	TonB-dependent receptor
EH203_RS18945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EH203_RS18950	COG0084	hydrolase, TatD family'
EH203_RS18960	COG5487	UPF0391 membrane protein
EH203_RS18965	COG2823	Periplasmic or secreted lipoprotein
EH203_RS18970	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EH203_RS18980	COG3726	membrane protein affecting hemolysin expression
EH203_RS18985	COG0560	Phosphoserine phosphatase
EH203_RS19000	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EH203_RS19010	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EH203_RS19020	COG0006	proline dipeptidase activity
EH203_RS19025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH203_RS19030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH203_RS19060	COG2130	NADP-dependent
EH203_RS19065	COG2862	Uncharacterized protein family, UPF0114
EH203_RS19100	COG3477	response to acidic pH
EH203_RS19115	COG0747	negative chemotaxis
EH203_RS19145	COG4977	sequence-specific DNA binding
EH203_RS19145	COG1917	Cupin 2, conserved barrel domain protein
EH203_RS19150	COG1917	Cupin 2, conserved barrel domain protein
EH203_RS19150	COG2169	Transcriptional regulator
EH203_RS19155	COG1070	Carbohydrate kinase
EH203_RS19160	COG4806	L-rhamnose isomerase
EH203_RS19165	COG0235	Class ii aldolase
EH203_RS19170	COG3254	rhamnose metabolic process
EH203_RS19175	COG0840	transmembrane signaling receptor activity
EH203_RS19185	COG0840	transmembrane signaling receptor activity
EH203_RS19190	COG0288	reversible hydration of carbon dioxide
EH203_RS19195	COG0659	secondary active sulfate transmembrane transporter activity
EH203_RS19225	COG1690	Belongs to the RtcB family
EH203_RS19230	COG4650	regulator
EH203_RS19245	COG1401	restriction endodeoxyribonuclease activity
EH203_RS19255	COG0583	DNA-binding transcription factor activity
EH203_RS19270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH203_RS19290	COG2850	peptidyl-arginine hydroxylation
EH203_RS19330	COG0582	viral genome integration into host DNA
EH203_RS19340	COG0795	lipopolysaccharide-transporting ATPase activity
EH203_RS19345	COG0795	lipopolysaccharide-transporting ATPase activity
EH203_RS19350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EH203_RS19355	COG2927	DNA polymerase III (CHI subunit)
EH203_RS19360	COG0525	valine-tRNA ligase activity
EH203_RS19365	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EH203_RS19370	COG0840	transmembrane signaling receptor activity
EH203_RS19375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EH203_RS19380	COG0501	Belongs to the peptidase M48B family
EH203_RS19395	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EH203_RS19400	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EH203_RS19405	COG2731	YhcH YjgK YiaL family protein
EH203_RS19410	COG0540	Belongs to the ATCase OTCase family
EH203_RS19415	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EH203_RS19435	COG0702	epimerase
EH203_RS19440	COG3787	Belongs to the UPF0306 family
EH203_RS19445	COG1733	regulation of RNA biosynthetic process
EH203_RS19450	COG2814	Major facilitator Superfamily
EH203_RS19455	COG0076	glutamate decarboxylase activity
EH203_RS19465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EH203_RS19490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EH203_RS19495	COG1518	maintenance of DNA repeat elements
EH203_RS19510	COG1857	crispr-associated protein
EH203_RS19530	COG1203	CRISPR-associated helicase, Cas3
EH203_RS19565	COG0848	biopolymer transport protein
EH203_RS19570	COG0811	peptide transport
EH203_RS19575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EH203_RS19590	COG0626	cystathionine gamma-synthase activity
EH203_RS19595	COG0586	Pfam SNARE associated Golgi protein
EH203_RS19600	COG2207	Transcriptional regulator
EH203_RS19605	COG0778	Nitroreductase
EH203_RS19610	COG1979	alcohol dehydrogenase
EH203_RS19615	COG0656	L-ascorbic acid biosynthetic process
EH203_RS19620	COG2188	Transcriptional regulator
EH203_RS19625	COG2132	Multicopper oxidase
EH203_RS19630	COG0204	Acyl-transferase
EH203_RS19635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EH203_RS19655	COG1629	transport
EH203_RS19655	COG4771	TonB-dependent receptor
EH203_RS19660	COG3711	transcriptional antiterminator
EH203_RS19660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH203_RS19665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH203_RS19665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH203_RS19665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH203_RS19670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH203_RS19675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH203_RS19675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH203_RS19685	COG0191	fructose-bisphosphate aldolase activity
EH203_RS19690	COG2249	NAD(P)H dehydrogenase (quinone) activity
EH203_RS19695	COG0583	DNA-binding transcription factor activity
EH203_RS19700	COG0187	DNA topoisomerase II activity
EH203_RS19705	COG3150	esterase
EH203_RS19710	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EH203_RS19715	COG3151	Protein conserved in bacteria
EH203_RS19720	COG0494	nUDIX hydrolase
EH203_RS19725	COG1538	Outer membrane efflux protein
EH203_RS19730	COG5463	Belongs to the UPF0441 family
EH203_RS19735	COG0754	glutathionylspermidine amidase activity
EH203_RS19740	COG3384	dioxygenase
EH203_RS19750	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EH203_RS19755	COG3107	peptidoglycan biosynthetic process
EH203_RS19760	COG0792	nuclease activity
EH203_RS19765	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EH203_RS19770	COG2823	Periplasmic or secreted lipoprotein
EH203_RS19780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EH203_RS19785	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EH203_RS19790	COG0784	Response regulator, receiver
EH203_RS19790	COG2198	Histidine kinase
EH203_RS19790	COG5002	protein histidine kinase activity
EH203_RS19795	COG1242	4 iron, 4 sulfur cluster binding
EH203_RS19800	COG0067	glutamate synthase
EH203_RS19800	COG0070	glutamate synthase
EH203_RS19800	COG0069	glutamate synthase activity
EH203_RS19805	COG0493	'glutamate synthase
EH203_RS19820	COG2969	positive regulation of protein catabolic process
EH203_RS19825	COG0625	glutathione transferase activity
EH203_RS19835	COG2186	Transcriptional regulator
EH203_RS19840	COG1028	Short-chain dehydrogenase reductase Sdr
EH203_RS19845	COG1063	alcohol dehydrogenase
EH203_RS19850	COG0477	Major facilitator Superfamily
EH203_RS19855	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EH203_RS19860	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EH203_RS19865	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EH203_RS19870	COG3105	Protein conserved in bacteria
EH203_RS19875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH203_RS19880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH203_RS19885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EH203_RS19890	COG5007	Belongs to the BolA IbaG family
EH203_RS19895	COG3113	response to antibiotic
EH203_RS19900	COG2854	intermembrane phospholipid transfer
EH203_RS19905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EH203_RS19910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EH203_RS19915	COG1127	ABC transporter
EH203_RS19920	COG0530	calcium, potassium:sodium antiporter activity
EH203_RS19925	COG0517	IMP dehydrogenase activity
EH203_RS19925	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EH203_RS19930	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EH203_RS19935	COG3117	lipopolysaccharide transmembrane transporter activity
EH203_RS19940	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EH203_RS19945	COG1137	ATPase activity
EH203_RS19950	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EH203_RS19955	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EH203_RS19960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH203_RS19965	COG1660	Displays ATPase and GTPase activities
EH203_RS19970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH203_RS19975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EH203_RS19980	COG0312	modulator of DNA gyrase
EH203_RS19985	COG3028	Belongs to the UPF0307 family
EH203_RS19995	COG1289	transmembrane transporter activity
EH203_RS20000	COG1566	PFAM secretion protein HlyD family protein
EH203_RS20010	COG0583	DNA-binding transcription factor activity
EH203_RS20030	COG0312	modulator of DNA gyrase
EH203_RS20035	COG3164	Protein of unknown function
EH203_RS20040	COG1530	ribonuclease E activity
EH203_RS20045	COG0424	maF-like protein
EH203_RS20050	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EH203_RS20055	COG1792	Involved in formation and maintenance of cell shape
EH203_RS20060	COG1077	Cell shape determining protein MreB Mrl
EH203_RS20065	COG2200	EAL domain
EH203_RS20065	COG2199	diguanylate cyclase activity
EH203_RS20070	COG0604	alcohol dehydrogenase
EH203_RS20075	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EH203_RS20080	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EH203_RS20085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EH203_RS20090	COG0511	ligase activity, forming carbon-carbon bonds
EH203_RS20095	COG0439	Biotin carboxylase
EH203_RS20100	COG3585	molybdate ion transport
EH203_RS20105	COG3924	membrane
EH203_RS20110	COG4145	pantothenate transmembrane transporter activity
EH203_RS20115	COG2264	protein methyltransferase activity
EH203_RS20130	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EH203_RS20150	COG1162	GTPase activity
EH203_RS20165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH203_RS20170	COG0765	amino acid transport
EH203_RS20175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH203_RS20180	COG4597	amino acid ABC transporter
EH203_RS20185	COG0765	amino acid transport
EH203_RS20190	COG1126	abc transporter atp-binding protein
EH203_RS20220	COG0138	bifunctional purine biosynthesis protein purh
EH203_RS20225	COG0151	Belongs to the GarS family
EH203_RS20240	COG3068	Protein conserved in bacteria
EH203_RS20245	COG1515	deoxyribonuclease V activity
EH203_RS20250	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EH203_RS20255	COG2816	NAD+ diphosphatase activity
EH203_RS20260	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EH203_RS20265	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EH203_RS20270	COG0352	thiamine-phosphate diphosphorylase activity
EH203_RS20275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EH203_RS20280	COG2104	thiamine diphosphate biosynthetic process
EH203_RS20285	COG2022	thiamine diphosphate biosynthetic process
EH203_RS20295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH203_RS20300	COG5457	Domain of unknown function (DUF1127)
EH203_RS20305	COG0477	Major facilitator Superfamily
EH203_RS20310	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EH203_RS20315	COG0085	RNA polymerase activity
EH203_RS20320	COG0222	ribosome binding
EH203_RS20325	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EH203_RS20330	COG0081	regulation of translation
EH203_RS20335	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EH203_RS20340	COG0250	Participates in transcription elongation, termination and antitermination
EH203_RS20345	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EH203_RS20380	COG1072	(Pantothenic acid kinase))
EH203_RS20385	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EH203_RS20385	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EH203_RS20390	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EH203_RS20425	COG1739	Uncharacterized protein family UPF0029
EH203_RS20430	COG0006	proline dipeptidase activity
EH203_RS20435	COG1250	3-hydroxyacyl-CoA dehydrogenase
EH203_RS20435	COG1024	Enoyl-CoA hydratase
EH203_RS20440	COG0183	Belongs to the thiolase family
EH203_RS20450	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EH203_RS20455	COG0250	Participates in transcription elongation, termination and antitermination
EH203_RS20465	COG0084	hydrolase, TatD family'
EH203_RS20470	COG0805	protein transport
EH203_RS20475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EH203_RS20480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EH203_RS20485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EH203_RS20495	COG2226	methyltransferase
EH203_RS20505	COG0165	Argininosuccinate lyase
EH203_RS20510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EH203_RS20515	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EH203_RS20520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EH203_RS20530	COG4948	Mandelate Racemase Muconate Lactonizing
EH203_RS20535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH203_RS20535	COG1263	PTS System
EH203_RS20535	COG2190	(PTS) system
EH203_RS20540	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EH203_RS20550	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EH203_RS20555	COG0412	Dienelactone hydrolase
EH203_RS20560	COG0840	transmembrane signaling receptor activity
EH203_RS20565	COG0840	transmembrane signaling receptor activity
EH203_RS20570	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EH203_RS20575	COG0583	DNA-binding transcription factor activity
EH203_RS20595	COG3157	Type VI secretion system effector, Hcp
EH203_RS20605	COG1045	serine acetyltransferase
EH203_RS20610	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EH203_RS20615	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EH203_RS20620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH203_RS20625	COG4942	peptidase
EH203_RS20630	COG2861	carbohydrate metabolic process
EH203_RS20635	COG1063	alcohol dehydrogenase
EH203_RS20640	COG0156	8-amino-7-oxononanoate synthase activity
EH203_RS20645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH203_RS20655	COG0859	PFAM glycosyl transferase family 9
EH203_RS20660	COG0859	PFAM glycosyl transferase family 9
EH203_RS20675	COG1519	Transferase
EH203_RS20680	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EH203_RS20685	COG0859	PFAM glycosyl transferase family 9
EH203_RS20690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EH203_RS20695	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EH203_RS20700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EH203_RS20705	COG2003	Belongs to the UPF0758 family
EH203_RS20710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EH203_RS20715	COG0756	dUTP diphosphatase activity
EH203_RS20720	COG1309	transcriptional regulator
EH203_RS20725	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EH203_RS20730	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EH203_RS20735	COG4948	Mandelate Racemase Muconate Lactonizing
EH203_RS20740	COG4172	Belongs to the ABC transporter superfamily
EH203_RS20745	COG0747	negative chemotaxis
EH203_RS20750	COG0601	transmembrane transport
EH203_RS20755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH203_RS20770	COG1446	asparaginase
EH203_RS20775	COG0583	DNA-binding transcription factor activity
EH203_RS20780	COG1561	YicC-like family, N-terminal region
EH203_RS20785	COG0582	viral genome integration into host DNA
EH203_RS20845	COG3645	SOS response
EH203_RS20860	COG2226	methyltransferase
EH203_RS20885	COG0628	permease
EH203_RS20890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EH203_RS20890	COG0456	acetyltransferase
EH203_RS20895	COG1304	FMN binding
EH203_RS20900	COG1012	belongs to the aldehyde dehydrogenase family
EH203_RS20910	COG3239	Fatty acid desaturase
EH203_RS20940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH203_RS20945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EH203_RS20950	COG3136	membrane protein required for alginate biosynthesis
EH203_RS20965	COG4677	pectinesterase activity
EH203_RS20970	COG2771	luxR family
EH203_RS20980	COG0137	argininosuccinate synthase activity
EH203_RS20990	COG1609	Transcriptional regulator
EH203_RS20990	COG2207	Transcriptional regulator
EH203_RS20995	COG4214	carbohydrate transport
EH203_RS21000	COG1129	ABC transporter
EH203_RS21005	COG4213	ABC transporter substrate-binding protein
EH203_RS21010	COG2115	Belongs to the xylose isomerase family
EH203_RS21015	COG1070	Carbohydrate kinase
EH203_RS21020	COG3274	enterobacterial common antigen metabolic process
EH203_RS21025	COG1012	belongs to the aldehyde dehydrogenase family
EH203_RS21030	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EH203_RS21035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EH203_RS21050	COG3722	fumarate hydratase activity
EH203_RS21055	COG0246	Mannitol dehydrogenase
EH203_RS21060	COG2213	PTS system mannitol-specific
EH203_RS21060	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH203_RS21070	COG0751	glycine-tRNA ligase activity
EH203_RS21075	COG0752	glycyl-tRNA synthetase alpha subunit
EH203_RS21080	COG0730	response to heat
EH203_RS21085	COG2818	Glycosylase
EH203_RS21090	COG0456	acetyltransferase
EH203_RS21100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH203_RS21120	COG4172	Belongs to the ABC transporter superfamily
EH203_RS21125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH203_RS21140	COG1280	lysine exporter protein (LysE YggA)
EH203_RS21145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EH203_RS21150	COG2375	cellular response to nickel ion
EH203_RS21170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH203_RS21175	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EH203_RS21195	COG2214	Heat shock protein DnaJ domain protein
EH203_RS21200	COG0443	Heat shock 70 kDa protein
EH203_RS21215	COG3712	iron ion homeostasis
EH203_RS21220	COG1595	DNA-templated transcription, initiation
EH203_RS21225	COG1629	transport
EH203_RS21235	COG0742	ribosomal rna small subunit methyltransferase
EH203_RS21240	COG0737	Belongs to the 5'-nucleotidase family
EH203_RS21250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EH203_RS21255	COG0589	response to stress
EH203_RS21265	COG0306	phosphate transporter
EH203_RS21270	COG2081	HI0933 family
EH203_RS21275	COG2207	Transcriptional regulator
EH203_RS21280	COG2200	EAL domain
EH203_RS21295	COG2194	sulfuric ester hydrolase activity
EH203_RS21300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EH203_RS21305	COG0194	GDP metabolic process
EH203_RS21310	COG1758	RNA polymerase activity
EH203_RS21315	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EH203_RS21320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH203_RS21325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EH203_RS21330	COG2233	PERMEase
EH203_RS21335	COG2982	Protein involved in outer membrane biogenesis
EH203_RS21340	COG0456	acetyltransferase
EH203_RS21345	COG1490	D-aminoacyl-tRNA deacylase activity
EH203_RS21350	COG1011	Hydrolase
EH203_RS21360	COG0174	glutamine synthetase
EH203_RS21365	COG3852	Histidine kinase
EH203_RS21380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EH203_RS21385	COG3078	GTPase activator activity
EH203_RS21395	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EH203_RS21400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH203_RS21400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH203_RS21410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EH203_RS21415	COG3084	Protein conserved in bacteria
EH203_RS21420	COG0746	molybdenum cofactor guanylyltransferase activity
EH203_RS21455	COG1609	Transcriptional regulator
EH203_RS21460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH203_RS21465	COG1879	ABC-type sugar transport system periplasmic component
EH203_RS21470	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH203_RS21475	COG1129	ABC transporter
EH203_RS21480	COG1869	D-ribose catabolic process
EH203_RS21485	COG3111	PFAM Bacterial OB fold (BOF) protein
EH203_RS21490	COG0745	RESPONSE REGULATOR receiver
EH203_RS21495	COG0642	Histidine kinase
EH203_RS21500	COG3158	transport of potassium into the cell
EH203_RS21505	COG0714	Associated with various cellular activities
EH203_RS21510	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EH203_RS21515	COG2502	aspartate--ammonia ligase
EH203_RS21520	COG1522	sequence-specific DNA binding
EH203_RS21525	COG0716	FMN binding
EH203_RS21530	COG0445	tRNA wobble uridine modification
EH203_RS21535	COG0357	Ribosomal RNA small subunit methyltransferase G
EH203_RS21540	COG3312	ion transport
EH203_RS21545	COG0356	it plays a direct role in the translocation of protons across the membrane
EH203_RS21555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EH203_RS21560	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EH203_RS21565	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EH203_RS21570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EH203_RS21575	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EH203_RS21580	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EH203_RS21590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EH203_RS21595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EH203_RS21605	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EH203_RS21610	COG0573	inorganic phosphate transmembrane transporter activity
EH203_RS21615	COG0581	inorganic phosphate transmembrane transporter activity
EH203_RS21620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EH203_RS21630	COG1396	sequence-specific DNA binding
EH203_RS21635	COG3135	benzoate transporter
EH203_RS21640	COG0346	lactoylglutathione lyase activity
EH203_RS21650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH203_RS21655	COG0765	amino acid transport
EH203_RS21660	COG0765	amino acid transport
EH203_RS21665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH203_RS21670	COG2252	PERMEase
EH203_RS21675	COG2091	lysine biosynthetic process via aminoadipic acid
EH203_RS21680	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH203_RS21685	COG0493	'glutamate synthase
EH203_RS21685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH203_RS21715	COG1733	regulation of RNA biosynthetic process
EH203_RS21720	COG0702	epimerase
EH203_RS21730	COG1396	sequence-specific DNA binding
EH203_RS21755	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EH203_RS21760	COG0706	membrane insertase activity
EH203_RS21770	COG0594	ribonuclease P activity
EH203_RS21775	COG0230	Belongs to the bacterial ribosomal protein bL34 family