locus-tag	class	description
EH204_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EH204_RS00010	COG0592	DNA-directed DNA polymerase activity
EH204_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EH204_RS00020	COG0187	DNA topoisomerase II activity
EH204_RS00035	COG0840	transmembrane signaling receptor activity
EH204_RS00040	COG1609	Transcriptional regulator
EH204_RS00045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH204_RS00050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH204_RS00055	COG1447	Phosphotransferase system cellobiose-specific component IIA
EH204_RS00060	COG2723	6-phospho-beta-galactosidase activity
EH204_RS00065	COG0561	phosphatase activity
EH204_RS00070	COG3157	Type VI secretion system effector, Hcp
EH204_RS00090	COG0747	negative chemotaxis
EH204_RS00110	COG0601	transmembrane transport
EH204_RS00115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH204_RS00130	COG1116	anion transmembrane transporter activity
EH204_RS00135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH204_RS00140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH204_RS00145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH204_RS00155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH204_RS00155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH204_RS00160	COG2723	6-phospho-beta-galactosidase activity
EH204_RS00170	COG0823	Involved in the tonB-independent uptake of proteins
EH204_RS00175	COG5645	(Lipo)protein
EH204_RS00180	COG0071	Belongs to the small heat shock protein (HSP20) family
EH204_RS00185	COG0071	Belongs to the small heat shock protein (HSP20) family
EH204_RS00190	COG2985	domain, Protein
EH204_RS00190	COG0569	domain protein
EH204_RS00195	COG0471	metal ion transport
EH204_RS00200	COG3290	protein histidine kinase activity
EH204_RS00205	COG4565	transcriptional regulatory protein
EH204_RS00215	COG3493	citrate carrier protein
EH204_RS00220	COG0747	negative chemotaxis
EH204_RS00230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH204_RS00235	COG0444	Belongs to the ABC transporter superfamily
EH204_RS00240	COG4608	Belongs to the ABC transporter superfamily
EH204_RS00280	COG3501	Rhs element vgr protein
EH204_RS00290	COG3977	Valine--pyruvate aminotransferase
EH204_RS00320	COG2831	hemolysin activation secretion protein
EH204_RS00325	COG0457	Tetratricopeptide repeat
EH204_RS00325	COG3118	belongs to the thioredoxin family
EH204_RS00335	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EH204_RS00340	COG1215	transferase activity, transferring glycosyl groups
EH204_RS00345	COG1215	transferase activity, transferring glycosyl groups
EH204_RS00350	COG1192	Involved in chromosome partitioning
EH204_RS00370	COG2194	sulfuric ester hydrolase activity
EH204_RS00375	COG2200	EAL domain
EH204_RS00375	COG2199	diguanylate cyclase activity
EH204_RS00380	COG1301	dicarboxylic acid transport
EH204_RS00385	COG0612	Peptidase, M16
EH204_RS00390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH204_RS00395	COG1295	ribonuclease BN
EH204_RS00400	COG0477	Major facilitator Superfamily
EH204_RS00410	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EH204_RS00415	COG0425	Belongs to the sulfur carrier protein TusA family
EH204_RS00425	COG3714	YhhN family
EH204_RS00440	COG3776	membrane
EH204_RS00445	COG0742	ribosomal rna small subunit methyltransferase
EH204_RS00450	COG0552	protein localization to endoplasmic reticulum
EH204_RS00455	COG2884	Cell division ATP-binding protein ftsE
EH204_RS00460	COG2177	Part of the ABC transporter FtsEX involved in
EH204_RS00475	COG0683	leucine binding
EH204_RS00480	COG0559	Belongs to the binding-protein-dependent transport system permease family
EH204_RS00485	COG4177	L-phenylalanine transmembrane transporter activity
EH204_RS00490	COG0411	ABC transporter
EH204_RS00495	COG0410	ABC transporter
EH204_RS00500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH204_RS00510	COG0840	transmembrane signaling receptor activity
EH204_RS00515	COG0840	transmembrane signaling receptor activity
EH204_RS00520	COG0840	transmembrane signaling receptor activity
EH204_RS00525	COG2610	gluconate transmembrane transporter activity
EH204_RS00530	COG3622	Belongs to the hyi family
EH204_RS00535	COG0235	Class ii aldolase
EH204_RS00545	COG2084	Dehydrogenase
EH204_RS00550	COG1349	DNA-binding transcription factor activity
EH204_RS00590	COG3609	addiction module antidote protein, CC2985 family
EH204_RS00595	COG1653	transport
EH204_RS00600	COG1175	transmembrane transport
EH204_RS00605	COG0395	ABC-type sugar transport system, permease component
EH204_RS00610	COG3842	ATPase activity
EH204_RS00615	COG0584	glycerophosphoryl diester phosphodiesterase
EH204_RS00630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EH204_RS00645	COG2205	protein histidine kinase activity
EH204_RS00650	COG0745	RESPONSE REGULATOR receiver
EH204_RS00655	COG3678	ATP-independent chaperone mediated protein folding
EH204_RS00670	COG3831	ATPase activity
EH204_RS00675	COG0714	Associated with various cellular activities
EH204_RS00680	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EH204_RS00685	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EH204_RS00695	COG2814	Major facilitator Superfamily
EH204_RS00700	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EH204_RS00705	COG0205	6-phosphofructokinase activity
EH204_RS00710	COG0583	DNA-binding transcription factor activity
EH204_RS00750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH204_RS00755	COG1116	anion transmembrane transporter activity
EH204_RS00765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EH204_RS00770	COG2957	Belongs to the agmatine deiminase family
EH204_RS00785	COG0149	triose-phosphate isomerase activity
EH204_RS00795	COG3152	Membrane
EH204_RS00805	COG1494	fructose-1,6-bisphosphatase
EH204_RS00815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EH204_RS00820	COG3074	FtsZ-dependent cytokinesis
EH204_RS00825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EH204_RS00830	COG1575	Belongs to the MenA family. Type 1 subfamily
EH204_RS00835	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EH204_RS00840	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EH204_RS00845	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EH204_RS00850	COG1609	Transcriptional regulator
EH204_RS00855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EH204_RS00860	COG0254	rRNA binding
EH204_RS00865	COG1598	PFAM Uncharacterised protein family UPF0150
EH204_RS00875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH204_RS00885	COG1120	ATPase activity
EH204_RS00890	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
EH204_RS00895	COG0626	cystathionine gamma-synthase activity
EH204_RS00900	COG0460	homoserine dehydrogenase
EH204_RS00900	COG0527	aspartate kinase activity
EH204_RS00905	COG3842	ATPase activity
EH204_RS00920	COG4149	molybdate abc transporter
EH204_RS00925	COG1609	Transcriptional regulator
EH204_RS00930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EH204_RS00945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH204_RS00960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EH204_RS00965	COG4206	TonB-dependent receptor
EH204_RS00970	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EH204_RS00995	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EH204_RS01000	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EH204_RS01000	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EH204_RS01005	COG1072	(Pantothenic acid kinase))
EH204_RS01040	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EH204_RS01045	COG0250	Participates in transcription elongation, termination and antitermination
EH204_RS01050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EH204_RS01055	COG0081	regulation of translation
EH204_RS01060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EH204_RS01065	COG0222	ribosome binding
EH204_RS01070	COG0085	RNA polymerase activity
EH204_RS01075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EH204_RS01080	COG0477	Major facilitator Superfamily
EH204_RS01085	COG5457	Domain of unknown function (DUF1127)
EH204_RS01090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH204_RS01100	COG2022	thiamine diphosphate biosynthetic process
EH204_RS01105	COG2104	thiamine diphosphate biosynthetic process
EH204_RS01110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EH204_RS01115	COG0352	thiamine-phosphate diphosphorylase activity
EH204_RS01120	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EH204_RS01125	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EH204_RS01130	COG2816	NAD+ diphosphatase activity
EH204_RS01135	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EH204_RS01140	COG1515	deoxyribonuclease V activity
EH204_RS01145	COG3068	Protein conserved in bacteria
EH204_RS01160	COG0151	Belongs to the GarS family
EH204_RS01165	COG0138	bifunctional purine biosynthesis protein purh
EH204_RS01195	COG1126	abc transporter atp-binding protein
EH204_RS01200	COG0765	amino acid transport
EH204_RS01205	COG4597	amino acid ABC transporter
EH204_RS01210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH204_RS01215	COG0765	amino acid transport
EH204_RS01220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH204_RS01260	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EH204_RS01275	COG2264	protein methyltransferase activity
EH204_RS01280	COG4145	pantothenate transmembrane transporter activity
EH204_RS01285	COG3924	membrane
EH204_RS01290	COG3585	molybdate ion transport
EH204_RS01295	COG0439	Biotin carboxylase
EH204_RS01300	COG0511	ligase activity, forming carbon-carbon bonds
EH204_RS01305	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EH204_RS01310	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EH204_RS01315	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EH204_RS01320	COG0604	alcohol dehydrogenase
EH204_RS01325	COG2199	diguanylate cyclase activity
EH204_RS01325	COG2200	EAL domain
EH204_RS01330	COG1077	Cell shape determining protein MreB Mrl
EH204_RS01335	COG1792	Involved in formation and maintenance of cell shape
EH204_RS01340	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EH204_RS01345	COG0424	maF-like protein
EH204_RS01350	COG1530	ribonuclease E activity
EH204_RS01355	COG3164	Protein of unknown function
EH204_RS01360	COG0312	modulator of DNA gyrase
EH204_RS01375	COG0583	DNA-binding transcription factor activity
EH204_RS01385	COG1566	PFAM secretion protein HlyD family protein
EH204_RS01390	COG1289	transmembrane transporter activity
EH204_RS01400	COG3028	Belongs to the UPF0307 family
EH204_RS01405	COG0312	modulator of DNA gyrase
EH204_RS01410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EH204_RS01415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH204_RS01420	COG1660	Displays ATPase and GTPase activities
EH204_RS01425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH204_RS01430	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EH204_RS01435	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EH204_RS01440	COG1137	ATPase activity
EH204_RS01445	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EH204_RS01450	COG3117	lipopolysaccharide transmembrane transporter activity
EH204_RS01455	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EH204_RS01460	COG0517	IMP dehydrogenase activity
EH204_RS01460	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EH204_RS01465	COG0530	calcium, potassium:sodium antiporter activity
EH204_RS01470	COG1127	ABC transporter
EH204_RS01475	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EH204_RS01480	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EH204_RS01485	COG2854	intermembrane phospholipid transfer
EH204_RS01490	COG3113	response to antibiotic
EH204_RS01495	COG5007	Belongs to the BolA IbaG family
EH204_RS01500	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EH204_RS01505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH204_RS01510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH204_RS01515	COG3105	Protein conserved in bacteria
EH204_RS01520	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EH204_RS01525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EH204_RS01530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EH204_RS01535	COG0477	Major facilitator Superfamily
EH204_RS01540	COG1063	alcohol dehydrogenase
EH204_RS01545	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS01550	COG2186	Transcriptional regulator
EH204_RS01560	COG0625	glutathione transferase activity
EH204_RS01565	COG2969	positive regulation of protein catabolic process
EH204_RS01580	COG0493	'glutamate synthase
EH204_RS01585	COG0067	glutamate synthase
EH204_RS01585	COG0069	glutamate synthase activity
EH204_RS01585	COG0070	glutamate synthase
EH204_RS01590	COG1242	4 iron, 4 sulfur cluster binding
EH204_RS01595	COG5002	protein histidine kinase activity
EH204_RS01595	COG0784	Response regulator, receiver
EH204_RS01595	COG2198	Histidine kinase
EH204_RS01600	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EH204_RS01605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EH204_RS01615	COG2823	Periplasmic or secreted lipoprotein
EH204_RS01620	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EH204_RS01625	COG0792	nuclease activity
EH204_RS01630	COG3107	peptidoglycan biosynthetic process
EH204_RS01635	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EH204_RS01655	COG3384	dioxygenase
EH204_RS01660	COG0754	glutathionylspermidine amidase activity
EH204_RS01665	COG5463	Belongs to the UPF0441 family
EH204_RS01670	COG1538	Outer membrane efflux protein
EH204_RS01675	COG0494	nUDIX hydrolase
EH204_RS01680	COG3151	Protein conserved in bacteria
EH204_RS01685	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EH204_RS01690	COG3150	esterase
EH204_RS01695	COG0187	DNA topoisomerase II activity
EH204_RS01700	COG0583	DNA-binding transcription factor activity
EH204_RS01705	COG2249	NAD(P)H dehydrogenase (quinone) activity
EH204_RS01710	COG0191	fructose-bisphosphate aldolase activity
EH204_RS01720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH204_RS01720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH204_RS01725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH204_RS01730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH204_RS01730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH204_RS01730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH204_RS01735	COG3711	transcriptional antiterminator
EH204_RS01735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH204_RS01740	COG4771	TonB-dependent receptor
EH204_RS01740	COG1629	transport
EH204_RS01760	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EH204_RS01765	COG0204	Acyl-transferase
EH204_RS01770	COG2132	Multicopper oxidase
EH204_RS01775	COG2188	Transcriptional regulator
EH204_RS01780	COG0656	L-ascorbic acid biosynthetic process
EH204_RS01785	COG1979	alcohol dehydrogenase
EH204_RS01790	COG0778	Nitroreductase
EH204_RS01795	COG2207	Transcriptional regulator
EH204_RS01800	COG0586	Pfam SNARE associated Golgi protein
EH204_RS01805	COG0626	cystathionine gamma-synthase activity
EH204_RS01820	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EH204_RS01825	COG0811	peptide transport
EH204_RS01830	COG0848	biopolymer transport protein
EH204_RS01865	COG1203	CRISPR-associated helicase, Cas3
EH204_RS01875	COG4680	protein conserved in bacteria
EH204_RS01890	COG1857	crispr-associated protein
EH204_RS01905	COG1518	maintenance of DNA repeat elements
EH204_RS01910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EH204_RS01935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EH204_RS01950	COG2814	Major facilitator Superfamily
EH204_RS01955	COG1733	regulation of RNA biosynthetic process
EH204_RS01960	COG3787	Belongs to the UPF0306 family
EH204_RS01965	COG0702	epimerase
EH204_RS01985	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EH204_RS01990	COG0540	Belongs to the ATCase OTCase family
EH204_RS01995	COG2731	YhcH YjgK YiaL family protein
EH204_RS02000	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EH204_RS02005	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EH204_RS02020	COG0501	Belongs to the peptidase M48B family
EH204_RS02025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EH204_RS02030	COG0840	transmembrane signaling receptor activity
EH204_RS02035	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EH204_RS02040	COG0525	valine-tRNA ligase activity
EH204_RS02045	COG2927	DNA polymerase III (CHI subunit)
EH204_RS02050	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EH204_RS02055	COG0795	lipopolysaccharide-transporting ATPase activity
EH204_RS02060	COG0795	lipopolysaccharide-transporting ATPase activity
EH204_RS02080	COG1104	cysteine desulfurase activity
EH204_RS02150	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EH204_RS02160	COG1136	(ABC) transporter
EH204_RS02190	COG2304	oxidoreductase activity
EH204_RS02195	COG2850	peptidyl-arginine hydroxylation
EH204_RS02215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH204_RS02230	COG0583	DNA-binding transcription factor activity
EH204_RS02255	COG4650	regulator
EH204_RS02260	COG1690	Belongs to the RtcB family
EH204_RS02290	COG0659	secondary active sulfate transmembrane transporter activity
EH204_RS02295	COG0288	reversible hydration of carbon dioxide
EH204_RS02300	COG0840	transmembrane signaling receptor activity
EH204_RS02310	COG0840	transmembrane signaling receptor activity
EH204_RS02315	COG3254	rhamnose metabolic process
EH204_RS02320	COG0235	Class ii aldolase
EH204_RS02325	COG4806	L-rhamnose isomerase
EH204_RS02330	COG1070	Carbohydrate kinase
EH204_RS02335	COG2169	Transcriptional regulator
EH204_RS02335	COG1917	Cupin 2, conserved barrel domain protein
EH204_RS02340	COG4977	sequence-specific DNA binding
EH204_RS02340	COG1917	Cupin 2, conserved barrel domain protein
EH204_RS02370	COG0747	negative chemotaxis
EH204_RS02385	COG3477	response to acidic pH
EH204_RS02420	COG2862	Uncharacterized protein family, UPF0114
EH204_RS02425	COG2130	NADP-dependent
EH204_RS02450	COG3157	Type VI secretion system effector, Hcp
EH204_RS02455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH204_RS02460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH204_RS02465	COG0006	proline dipeptidase activity
EH204_RS02475	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EH204_RS02500	COG0560	Phosphoserine phosphatase
EH204_RS02505	COG3726	membrane protein affecting hemolysin expression
EH204_RS02515	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EH204_RS02520	COG2823	Periplasmic or secreted lipoprotein
EH204_RS02525	COG5487	UPF0391 membrane protein
EH204_RS02535	COG0084	hydrolase, TatD family'
EH204_RS02540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EH204_RS02550	COG4771	TonB-dependent receptor
EH204_RS02560	COG1169	isochorismate synthase
EH204_RS02565	COG1021	2,3-dihydroxybenzoate-AMP ligase
EH204_RS02570	COG1535	isochorismatase
EH204_RS02570	COG3433	isochorismatase activity
EH204_RS02575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH204_RS02580	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS02590	COG3321	synthase
EH204_RS02590	COG0300	oxidoreductase activity
EH204_RS02590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH204_RS02590	COG0318	PFAM AMP-dependent synthetase and ligase
EH204_RS02590	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS02655	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EH204_RS02660	COG0732	type I restriction modification DNA specificity domain
EH204_RS02670	COG3423	Transcriptional regulator
EH204_RS02690	COG1309	transcriptional regulator
EH204_RS02700	COG1324	tolerance protein
EH204_RS02705	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EH204_RS02720	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EH204_RS02725	COG0459	protein refolding
EH204_RS02730	COG3161	chorismate lyase activity
EH204_RS02735	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EH204_RS02740	COG2937	Belongs to the GPAT DAPAT family
EH204_RS02745	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EH204_RS02755	COG3237	CsbD-like
EH204_RS02765	COG0735	belongs to the Fur family
EH204_RS02770	COG1741	Belongs to the pirin family
EH204_RS02775	COG0583	DNA-binding transcription factor activity
EH204_RS02780	COG0435	Glutathione S-transferase
EH204_RS02785	COG2259	Doxx family
EH204_RS02795	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EH204_RS02800	COG4575	ribosome binding
EH204_RS02805	COG1422	Protein of unknown function (DUF1090)
EH204_RS02815	COG0586	Pfam SNARE associated Golgi protein
EH204_RS02825	COG2271	Major facilitator Superfamily
EH204_RS02830	COG1904	glucuronate isomerase
EH204_RS02835	COG0246	Mannitol dehydrogenase
EH204_RS02840	COG2721	sulfolactate sulfo-lyase activity
EH204_RS02850	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EH204_RS02855	COG0861	Integral membrane protein TerC family
EH204_RS02860	COG0673	inositol 2-dehydrogenase activity
EH204_RS02865	COG2813	Specifically methylates the guanine in position
EH204_RS02870	COG0446	pyridine nucleotide-disulphide oxidoreductase
EH204_RS02870	COG1902	pentaerythritol trinitrate reductase activity
EH204_RS02880	COG3678	ATP-independent chaperone mediated protein folding
EH204_RS02910	COG0583	DNA-binding transcription factor activity
EH204_RS02915	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EH204_RS02915	COG2755	lipolytic protein G-D-S-L family
EH204_RS02925	COG3663	DNA glycosylase
EH204_RS02930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH204_RS02935	COG0358	DNA primase activity
EH204_RS02945	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EH204_RS02950	COG1438	arginine binding
EH204_RS02955	COG0039	L-malate dehydrogenase activity
EH204_RS02975	COG0142	geranyltranstransferase activity
EH204_RS02980	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EH204_RS02985	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EH204_RS02990	COG0697	spore germination
EH204_RS02995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EH204_RS03000	COG2027	D-alanyl-D-alanine carboxypeptidase
EH204_RS03005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EH204_RS03010	COG1534	Rna-binding protein
EH204_RS03015	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EH204_RS03020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH204_RS03025	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EH204_RS03030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EH204_RS03035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EH204_RS03045	COG2130	NADP-dependent
EH204_RS03105	COG2197	response regulator
EH204_RS03115	COG0779	Required for maturation of 30S ribosomal subunits
EH204_RS03125	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EH204_RS03130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EH204_RS03135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EH204_RS03140	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EH204_RS03145	COG1185	polyribonucleotide nucleotidyltransferase activity
EH204_RS03160	COG0513	Belongs to the DEAD box helicase family
EH204_RS03165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH204_RS03185	COG3153	acetyltransferase
EH204_RS03190	COG2827	Endonuclease containing a URI domain
EH204_RS03195	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EH204_RS03200	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EH204_RS03205	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EH204_RS03210	COG0813	purine-nucleoside phosphorylase activity
EH204_RS03215	COG4178	(ABC) transporter
EH204_RS03225	COG3712	iron ion homeostasis
EH204_RS03230	COG1595	DNA-templated transcription, initiation
EH204_RS03240	COG0456	acetyltransferase
EH204_RS03245	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EH204_RS03250	COG2813	Specifically methylates the guanine in position
EH204_RS03255	COG0656	L-ascorbic acid biosynthetic process
EH204_RS03320	COG1454	alcohol dehydrogenase
EH204_RS03325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EH204_RS03330	COG0509	glycine decarboxylation via glycine cleavage system
EH204_RS03335	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EH204_RS03335	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EH204_RS03340	COG1733	regulation of RNA biosynthetic process
EH204_RS03345	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS03350	COG1175	transmembrane transport
EH204_RS03360	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EH204_RS03365	COG3842	ATPase activity
EH204_RS03370	COG1653	transport
EH204_RS03375	COG2211	Major facilitator Superfamily
EH204_RS03395	COG1272	protein, Hemolysin III
EH204_RS03400	COG0354	folic acid binding
EH204_RS03405	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EH204_RS03415	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EH204_RS03425	COG0716	FMN binding
EH204_RS03435	COG0477	Major facilitator Superfamily
EH204_RS03440	COG4974	Belongs to the 'phage' integrase family
EH204_RS03445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EH204_RS03450	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EH204_RS03460	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EH204_RS03470	COG1733	regulation of RNA biosynthetic process
EH204_RS03475	COG2207	Transcriptional regulator
EH204_RS03500	COG4319	ketosteroid isomerase
EH204_RS03510	COG1560	Kdo2-lipid A biosynthetic process
EH204_RS03520	COG2252	PERMEase
EH204_RS03525	COG0025	NhaP-type Na H and K H
EH204_RS03540	COG5002	protein histidine kinase activity
EH204_RS03540	COG3850	Histidine kinase
EH204_RS03560	COG4964	Belongs to the GSP D family
EH204_RS03640	COG5464	transposase or invertase
EH204_RS03645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EH204_RS03650	COG3162	membrane
EH204_RS03655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EH204_RS03665	COG4774	siderophore transport
EH204_RS03675	COG3712	iron ion homeostasis
EH204_RS03695	COG0246	Mannitol dehydrogenase
EH204_RS03700	COG2873	o-acetylhomoserine
EH204_RS03705	COG1376	ErfK ybiS ycfS ynhG family protein
EH204_RS03710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EH204_RS03715	COG3038	cytochrome b561
EH204_RS03720	COG1013	pyruvate-flavodoxin oxidoreductase activity
EH204_RS03720	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EH204_RS03720	COG0674	pyruvate-flavodoxin oxidoreductase activity
EH204_RS03720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH204_RS03735	COG1280	lysine exporter protein (LysE YggA)
EH204_RS03815	COG3012	SEC-C Motif Domain Protein
EH204_RS03820	COG0582	viral genome integration into host DNA
EH204_RS03830	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EH204_RS03835	COG2867	negative regulation of translational initiation
EH204_RS03840	COG2914	Belongs to the UPF0125 (RnfH) family
EH204_RS03850	COG0497	DNA recombination
EH204_RS03855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EH204_RS03860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EH204_RS03865	COG1914	H( )-stimulated, divalent metal cation uptake system
EH204_RS03870	COG1942	4-Oxalocrotonate Tautomerase
EH204_RS03875	COG0477	Major facilitator Superfamily
EH204_RS03880	COG0494	nUDIX hydrolase
EH204_RS03910	COG1609	Transcriptional regulator
EH204_RS03915	COG1126	abc transporter atp-binding protein
EH204_RS03920	COG0765	amino acid transport
EH204_RS03930	COG3711	transcriptional antiterminator
EH204_RS03935	COG2723	6-phospho-beta-galactosidase activity
EH204_RS03940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH204_RS03940	COG2190	(PTS) system
EH204_RS03940	COG1263	PTS System
EH204_RS03945	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EH204_RS03950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EH204_RS03955	COG0698	ribose 5-phosphate isomerase
EH204_RS03965	COG2376	Dihydroxyacetone kinase
EH204_RS03970	COG0149	triose-phosphate isomerase activity
EH204_RS03975	COG1082	Xylose isomerase domain protein TIM barrel
EH204_RS03980	COG2084	Dehydrogenase
EH204_RS04010	COG0814	amino acid
EH204_RS04015	COG1671	Belongs to the UPF0178 family
EH204_RS04020	COG0408	coproporphyrinogen oxidase activity
EH204_RS04025	COG0456	acetyltransferase
EH204_RS04040	COG0612	Peptidase, M16
EH204_RS04045	COG4178	(ABC) transporter
EH204_RS04055	COG2837	iron assimilation
EH204_RS04060	COG4150	thiosulfate binding
EH204_RS04065	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EH204_RS04070	COG4208	sulfate ABC transporter
EH204_RS04075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH204_RS04080	COG1136	(ABC) transporter
EH204_RS04080	COG0577	efflux transmembrane transporter activity
EH204_RS04085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH204_RS04090	COG0745	RESPONSE REGULATOR receiver
EH204_RS04095	COG2205	protein histidine kinase activity
EH204_RS04100	COG2190	(PTS) system
EH204_RS04110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH204_RS04115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH204_RS04120	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EH204_RS04125	COG3115	cell septum assembly
EH204_RS04130	COG0531	amino acid
EH204_RS04140	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EH204_RS04150	COG0446	pyridine nucleotide-disulphide oxidoreductase
EH204_RS04155	COG0426	domain, Protein
EH204_RS04155	COG1773	rubredoxin
EH204_RS04160	COG3604	Transcriptional regulator
EH204_RS04165	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EH204_RS04165	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EH204_RS04190	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EH204_RS04190	COG2169	Transcriptional regulator
EH204_RS04200	COG1053	succinate dehydrogenase
EH204_RS04205	COG3976	FMN-binding domain protein
EH204_RS04205	COG0431	NADPH-dependent FMN reductase
EH204_RS04205	COG1053	succinate dehydrogenase
EH204_RS04210	COG0477	Major facilitator Superfamily
EH204_RS04215	COG3301	Polysulphide reductase, NrfD
EH204_RS04220	COG0437	4 iron, 4 sulfur cluster binding
EH204_RS04230	COG0583	DNA-binding transcription factor activity
EH204_RS04235	COG4948	Mandelate Racemase Muconate Lactonizing
EH204_RS04240	COG1063	alcohol dehydrogenase
EH204_RS04245	COG0477	Major facilitator Superfamily
EH204_RS04250	COG0246	Mannitol dehydrogenase
EH204_RS04255	COG1802	Transcriptional regulator
EH204_RS04270	COG0811	peptide transport
EH204_RS04315	COG0583	DNA-binding transcription factor activity
EH204_RS04325	COG4773	Receptor
EH204_RS04330	COG4948	Mandelate Racemase Muconate Lactonizing
EH204_RS04340	COG1129	ABC transporter
EH204_RS04355	COG3121	Chaperone
EH204_RS04435	COG1846	Transcriptional regulator
EH204_RS04440	COG2814	Major facilitator Superfamily
EH204_RS04495	COG0297	glycogen (starch) synthase activity
EH204_RS04515	COG1045	serine acetyltransferase
EH204_RS04525	COG3423	Transcriptional regulator
EH204_RS04535	COG1982	Orn Lys Arg decarboxylase major
EH204_RS04555	COG5441	Belongs to the UPF0261 family
EH204_RS04560	COG5564	TIM-barrel signal transduction protein
EH204_RS04575	COG1917	Cupin 2, conserved barrel domain protein
EH204_RS04575	COG2169	Transcriptional regulator
EH204_RS04580	COG0741	lytic transglycosylase activity
EH204_RS04585	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EH204_RS04595	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EH204_RS04600	COG3171	Protein conserved in bacteria
EH204_RS04615	COG2188	Transcriptional regulator
EH204_RS04620	COG3624	Phosphonate C-P lyase system protein PhnG
EH204_RS04625	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EH204_RS04630	COG3626	phosphonate metabolism
EH204_RS04635	COG3627	carbon phosphorus lyase activity
EH204_RS04640	COG4107	phosphonate C-P lyase system protein PhnK
EH204_RS04645	COG4778	phosphonate C-P lyase system protein PhnL
EH204_RS04650	COG3454	Phosphonate metabolism
EH204_RS04660	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EH204_RS04670	COG3639	organic phosphonate transmembrane transporter activity
EH204_RS04675	COG0667	Aldo Keto reductase
EH204_RS04685	COG0861	Integral membrane protein TerC family
EH204_RS04690	COG3066	DNA modification
EH204_RS04705	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EH204_RS04710	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EH204_RS04720	COG4795	General secretion pathway protein
EH204_RS04735	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EH204_RS04740	COG1025	Belongs to the peptidase M16 family
EH204_RS04745	COG1074	ATP-dependent DNA helicase activity
EH204_RS04755	COG1609	Transcriptional regulator
EH204_RS04765	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EH204_RS04765	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EH204_RS04770	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH204_RS04790	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EH204_RS04795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EH204_RS04805	COG1473	amidohydrolase
EH204_RS04810	COG4172	Belongs to the ABC transporter superfamily
EH204_RS04815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH204_RS04825	COG0747	negative chemotaxis
EH204_RS04835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EH204_RS04840	COG2166	iron-sulfur cluster assembly
EH204_RS04845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH204_RS04855	COG0583	DNA-binding transcription factor activity
EH204_RS04860	COG2363	Small membrane protein
EH204_RS04865	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EH204_RS04870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH204_RS04875	COG1611	Belongs to the LOG family
EH204_RS04880	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EH204_RS04880	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EH204_RS04920	COG2171	N-acyltransferase activity
EH204_RS04925	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EH204_RS04930	COG0024	Methionine aminopeptidase
EH204_RS04935	COG0052	Belongs to the universal ribosomal protein uS2 family
EH204_RS04940	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EH204_RS04945	COG0528	UMP kinase activity
EH204_RS04950	COG0233	cytoplasmic translational termination
EH204_RS04955	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EH204_RS04960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EH204_RS04965	COG0575	Belongs to the CDS family
EH204_RS04970	COG0750	zinc metalloprotease
EH204_RS04975	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH204_RS04980	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EH204_RS04985	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH204_RS04990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EH204_RS04995	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH204_RS05000	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH204_RS05005	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EH204_RS05010	COG0587	DNA-directed DNA polymerase activity
EH204_RS05015	COG0825	malonyl-CoA metabolic process
EH204_RS05020	COG0346	lactoylglutathione lyase activity
EH204_RS05025	COG0037	tRNA processing
EH204_RS05030	COG4568	rho-dependent transcription termination
EH204_RS05040	COG4681	YaeQ
EH204_RS05045	COG3015	lipoprotein NlpE involved in copper resistance
EH204_RS05050	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EH204_RS05075	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EH204_RS05080	COG2824	Alkylphosphonate utilization operon protein PhnA
EH204_RS05085	COG2951	lytic endotransglycosylase activity
EH204_RS05125	COG2186	Transcriptional regulator
EH204_RS05130	COG1312	Catalyzes the dehydration of D-mannonate
EH204_RS05135	COG5297	Belongs to the glycosyl hydrolase family 6
EH204_RS05165	COG4615	Cyclic peptide transporter
EH204_RS05175	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EH204_RS05180	COG3123	guanosine phosphorylase activity
EH204_RS05200	COG2188	Transcriptional regulator
EH204_RS05210	COG2974	May be involved in recombination
EH204_RS05215	COG1940	carbohydrate kinase activity
EH204_RS05220	COG0419	ATPase involved in DNA repair
EH204_RS05225	COG0420	3'-5' exonuclease activity
EH204_RS05245	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EH204_RS05250	COG1114	Component of the transport system for branched-chain amino acids
EH204_RS05260	COG0668	transmembrane transport
EH204_RS05265	COG0450	alkyl hydroperoxide reductase
EH204_RS05270	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EH204_RS05275	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EH204_RS05280	COG0343	queuine tRNA-ribosyltransferase activity
EH204_RS05285	COG1862	Preprotein translocase
EH204_RS05295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EH204_RS05300	COG4238	major outer membrane lipoprotein
EH204_RS05305	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EH204_RS05310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EH204_RS05310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EH204_RS05315	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EH204_RS05320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EH204_RS05325	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EH204_RS05330	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EH204_RS05335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EH204_RS05340	COG0142	geranyltranstransferase activity
EH204_RS05345	COG1722	exodeoxyribonuclease VII activity
EH204_RS05350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH204_RS05350	COG0301	tRNA thio-modification
EH204_RS05355	COG0693	protein deglycase activity
EH204_RS05360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EH204_RS05365	COG1666	GTP binding
EH204_RS05370	COG2814	Major facilitator Superfamily
EH204_RS05375	COG0109	protoheme IX farnesyltransferase activity
EH204_RS05380	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EH204_RS05385	COG1845	cytochrome c oxidase, subunit III
EH204_RS05390	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EH204_RS05395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EH204_RS05400	COG2223	nitrite transmembrane transporter activity
EH204_RS05405	COG3056	Lipoprotein
EH204_RS05410	COG0271	Belongs to the BolA IbaG family
EH204_RS05415	COG0544	peptidyl-prolyl cis-trans isomerase activity
EH204_RS05420	COG0740	serine-type endopeptidase activity
EH204_RS05425	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EH204_RS05430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EH204_RS05435	COG0776	regulation of translation
EH204_RS05440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH204_RS05445	COG1555	photosystem II stabilization
EH204_RS05450	COG0824	Thioesterase
EH204_RS05455	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EH204_RS05460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH204_RS05465	COG1522	sequence-specific DNA binding
EH204_RS05470	COG1132	(ABC) transporter
EH204_RS05475	COG1132	(ABC) transporter
EH204_RS05480	COG0347	Belongs to the P(II) protein family
EH204_RS05485	COG0004	ammonium transporteR
EH204_RS05490	COG1946	Acyl-CoA thioesterase
EH204_RS05495	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EH204_RS05500	COG3695	enzyme binding
EH204_RS05520	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EH204_RS05525	COG0254	rRNA binding
EH204_RS05535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH204_RS05540	COG1309	transcriptional regulator
EH204_RS05555	COG2832	Protein of unknown function (DUF454)
EH204_RS05560	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EH204_RS05570	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EH204_RS05575	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EH204_RS05580	COG0326	Molecular chaperone. Has ATPase activity
EH204_RS05585	COG0563	adenylate kinase activity
EH204_RS05590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH204_RS05595	COG4651	solute:proton antiporter activity
EH204_RS05595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EH204_RS05600	COG0737	Belongs to the 5'-nucleotidase family
EH204_RS05615	COG1966	Carbon starvation protein
EH204_RS05620	COG2879	small protein
EH204_RS05625	COG0523	cobalamin synthesis protein
EH204_RS05630	COG5434	Belongs to the glycosyl hydrolase 28 family
EH204_RS05640	COG3735	TraB family
EH204_RS05655	COG2217	Heavy metal translocating P-type atpase
EH204_RS05665	COG1585	Membrane protein implicated in regulation of membrane protease activity
EH204_RS05670	COG0330	HflC and HflK could
EH204_RS05675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH204_RS05680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EH204_RS05685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EH204_RS05690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EH204_RS05700	COG0784	Response regulator, receiver
EH204_RS05700	COG2205	protein histidine kinase activity
EH204_RS05705	COG2197	response regulator
EH204_RS05710	COG2198	Histidine kinase
EH204_RS05710	COG0642	Histidine kinase
EH204_RS05715	COG2223	nitrite transmembrane transporter activity
EH204_RS05720	COG1169	isochorismate synthase
EH204_RS05725	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EH204_RS05730	COG0596	Alpha beta hydrolase
EH204_RS05735	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EH204_RS05740	COG1441	menaquinone biosynthetic process
EH204_RS05760	COG0814	amino acid
EH204_RS05770	COG3118	belongs to the thioredoxin family
EH204_RS05775	COG0300	oxidoreductase activity
EH204_RS05780	COG2755	lipolytic protein G-D-S-L family
EH204_RS05785	COG4181	ATPase activity
EH204_RS05790	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EH204_RS05795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH204_RS05810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EH204_RS05815	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EH204_RS05820	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EH204_RS05825	COG2233	PERMEase
EH204_RS05830	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EH204_RS05835	COG1393	Belongs to the ArsC family
EH204_RS05840	COG4783	chaperone-mediated protein folding
EH204_RS05845	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EH204_RS05850	COG2716	regulation of RNA biosynthetic process
EH204_RS05860	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EH204_RS05865	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EH204_RS05880	COG2707	UPF0756 membrane protein
EH204_RS05885	COG1444	tRNA N-acetyltransferase activity
EH204_RS05895	COG3118	belongs to the thioredoxin family
EH204_RS05910	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EH204_RS05915	COG3712	iron ion homeostasis
EH204_RS05920	COG1595	DNA-templated transcription, initiation
EH204_RS05925	COG4774	siderophore transport
EH204_RS05930	COG4178	(ABC) transporter
EH204_RS05945	COG3813	Protein conserved in bacteria
EH204_RS05950	COG0400	carboxylic ester hydrolase activity
EH204_RS05965	COG1876	peptidase activity
EH204_RS05970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EH204_RS05975	COG1393	Belongs to the ArsC family
EH204_RS05985	COG1794	racemase activity, acting on amino acids and derivatives
EH204_RS05990	COG1278	Cold shock
EH204_RS05995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EH204_RS06000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EH204_RS06005	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EH204_RS06010	COG0321	lipoyl(octanoyl) transferase activity
EH204_RS06015	COG2921	Belongs to the UPF0250 family
EH204_RS06020	COG1686	Belongs to the peptidase S11 family
EH204_RS06025	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EH204_RS06030	COG0772	Belongs to the SEDS family
EH204_RS06035	COG0768	penicillin binding
EH204_RS06040	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EH204_RS06045	COG0799	negative regulation of ribosome biogenesis
EH204_RS06050	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EH204_RS06055	COG1466	dna polymerase III delta subunit
EH204_RS06060	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EH204_RS06065	COG0495	leucyl-tRNA aminoacylation
EH204_RS06070	COG2888	peptidyl-tyrosine sulfation
EH204_RS06075	COG1126	abc transporter atp-binding protein
EH204_RS06080	COG0765	amino acid transport
EH204_RS06085	COG0765	amino acid transport
EH204_RS06095	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EH204_RS06100	COG4535	Mg2 and Co2 transporter CorC
EH204_RS06105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EH204_RS06110	COG1702	phosphate starvation-inducible protein PhoH
EH204_RS06115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH204_RS06120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH204_RS06175	COG0367	asparagine synthase
EH204_RS06180	COG1940	carbohydrate kinase activity
EH204_RS06180	COG1846	Transcriptional regulator
EH204_RS06185	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EH204_RS06190	COG0363	glucosamine-6-phosphate deaminase activity
EH204_RS06195	COG1263	PTS System
EH204_RS06195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH204_RS06195	COG2190	(PTS) system
EH204_RS06200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH204_RS06205	COG0735	belongs to the Fur family
EH204_RS06210	COG0716	FMN binding
EH204_RS06215	COG0840	transmembrane signaling receptor activity
EH204_RS06225	COG0596	Alpha beta hydrolase
EH204_RS06230	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EH204_RS06235	COG0033	Phosphoglucomutase
EH204_RS06240	COG3547	Transposase (IS116 IS110 IS902 family)
EH204_RS06250	COG0745	RESPONSE REGULATOR receiver
EH204_RS06255	COG2205	protein histidine kinase activity
EH204_RS06260	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EH204_RS06265	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EH204_RS06270	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EH204_RS06290	COG1840	ABC-type Fe3 transport system, periplasmic component
EH204_RS06295	COG3842	ATPase activity
EH204_RS06300	COG3272	Protein of unknown function (DUF1722)
EH204_RS06305	COG0415	Belongs to the DNA photolyase family
EH204_RS06310	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EH204_RS06315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EH204_RS06320	COG1984	allophanate hydrolase subunit 2
EH204_RS06325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EH204_RS06330	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EH204_RS06335	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EH204_RS06350	COG2009	succinate dehydrogenase
EH204_RS06355	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EH204_RS06360	COG1053	succinate dehydrogenase
EH204_RS06365	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EH204_RS06370	COG0567	Dehydrogenase, E1 component
EH204_RS06375	COG0508	dehydrogenase complex catalyzes the overall conversion of
EH204_RS06380	COG0045	succinate-CoA ligase (ADP-forming) activity
EH204_RS06385	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EH204_RS06395	COG1271	oxidase subunit
EH204_RS06400	COG1294	oxidase, subunit
EH204_RS06405	COG4890	Cyd operon protein YbgT
EH204_RS06410	COG3790	cyd operon protein YbgE
EH204_RS06415	COG0824	Thioesterase
EH204_RS06420	COG0811	peptide transport
EH204_RS06425	COG0848	biopolymer transport protein
EH204_RS06430	COG3064	Membrane
EH204_RS06435	COG0823	Involved in the tonB-independent uptake of proteins
EH204_RS06440	COG2885	chlorophyll binding
EH204_RS06445	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EH204_RS06470	COG1811	Na channel or pump
EH204_RS06480	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EH204_RS06490	COG1230	cation diffusion facilitator family transporter
EH204_RS06495	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EH204_RS06500	COG0588	phosphoglycerate mutase activity
EH204_RS06505	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH204_RS06510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH204_RS06530	COG2017	converts alpha-aldose to the beta-anomer
EH204_RS06535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EH204_RS06540	COG1119	ATPase activity
EH204_RS06545	COG3585	molybdate ion transport
EH204_RS06545	COG2005	Transcriptional regulator
EH204_RS06555	COG0725	ABC transporter, periplasmic molybdate-binding protein
EH204_RS06560	COG4149	molybdate abc transporter
EH204_RS06565	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EH204_RS06590	COG2211	Major facilitator Superfamily
EH204_RS06595	COG0837	glucose binding
EH204_RS06600	COG0561	phosphatase activity
EH204_RS06610	COG2706	6-phosphogluconolactonase activity
EH204_RS06625	COG2864	formate dehydrogenase
EH204_RS06630	COG0437	4 iron, 4 sulfur cluster binding
EH204_RS06640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH204_RS06640	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH204_RS06645	COG0489	protein tyrosine kinase activity
EH204_RS06650	COG0572	uridine kinase
EH204_RS06655	COG0717	Belongs to the dCTP deaminase family
EH204_RS06660	COG2982	Protein involved in outer membrane biogenesis
EH204_RS06665	COG3069	C4-dicarboxylate transmembrane transporter activity
EH204_RS06680	COG1253	flavin adenine dinucleotide binding
EH204_RS06685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH204_RS06705	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EH204_RS06715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EH204_RS06725	COG2244	polysaccharide biosynthetic process
EH204_RS06730	COG0463	Glycosyl transferase, family 2
EH204_RS06730	COG1216	Glycosyl transferase, family 2
EH204_RS06760	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EH204_RS06765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH204_RS06770	COG1051	belongs to the nudix hydrolase family
EH204_RS06780	COG1215	transferase activity, transferring glycosyl groups
EH204_RS06790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EH204_RS06815	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH204_RS06820	COG1605	Chorismate mutase
EH204_RS06830	COG2723	6-phospho-beta-galactosidase activity
EH204_RS06835	COG3711	transcriptional antiterminator
EH204_RS06840	COG3706	GGDEF domain
EH204_RS06860	COG3962	Belongs to the TPP enzyme family
EH204_RS06865	COG0673	inositol 2-dehydrogenase activity
EH204_RS06870	COG1879	ABC-type sugar transport system periplasmic component
EH204_RS06880	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH204_RS06890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH204_RS06900	COG3718	enzyme involved in inositol metabolism
EH204_RS06915	COG3842	ATPase activity
EH204_RS06920	COG4208	sulfate ABC transporter
EH204_RS06925	COG1840	ABC-type Fe3 transport system, periplasmic component
EH204_RS06935	COG2723	6-phospho-beta-galactosidase activity
EH204_RS06940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH204_RS06940	COG2190	(PTS) system
EH204_RS06940	COG1263	PTS System
EH204_RS06945	COG2203	Gaf domain
EH204_RS06945	COG2199	diguanylate cyclase activity
EH204_RS06955	COG3615	Tellurite resistance protein tehB
EH204_RS06965	COG0583	DNA-binding transcription factor activity
EH204_RS06970	COG0596	Alpha beta hydrolase
EH204_RS06980	COG1902	pentaerythritol trinitrate reductase activity
EH204_RS06990	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS06995	COG0604	alcohol dehydrogenase
EH204_RS07035	COG4227	nucleotidyltransferase activity
EH204_RS07065	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EH204_RS07075	COG3504	Conjugal transfer protein
EH204_RS07080	COG3736	Type IV secretory pathway, component VirB8
EH204_RS07130	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EH204_RS07150	COG3423	Transcriptional regulator
EH204_RS07165	COG0582	viral genome integration into host DNA
EH204_RS07190	COG1113	amino acid transport
EH204_RS07210	COG2197	response regulator
EH204_RS07215	COG0322	excinuclease ABC activity
EH204_RS07220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EH204_RS07240	COG0582	viral genome integration into host DNA
EH204_RS07245	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EH204_RS07265	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EH204_RS07300	COG1560	Kdo2-lipid A biosynthetic process
EH204_RS07315	COG3706	GGDEF domain
EH204_RS07325	COG0840	transmembrane signaling receptor activity
EH204_RS07330	COG0697	spore germination
EH204_RS07355	COG2198	Histidine kinase
EH204_RS07355	COG0643	Histidine kinase
EH204_RS07360	COG0835	chemotaxis
EH204_RS07365	COG0840	transmembrane signaling receptor activity
EH204_RS07370	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EH204_RS07380	COG0745	RESPONSE REGULATOR receiver
EH204_RS07390	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EH204_RS07395	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EH204_RS07410	COG2747	anti-sigma28 factor FlgM
EH204_RS07420	COG1815	bacterial-type flagellum-dependent cell motility
EH204_RS07425	COG1558	bacterial-type flagellum-dependent cell motility
EH204_RS07430	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EH204_RS07435	COG1749	Flagellar hook protein flgE
EH204_RS07440	COG4787	bacterial-type flagellum-dependent cell motility
EH204_RS07445	COG4786	Flagellar basal body rod
EH204_RS07450	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EH204_RS07455	COG1706	bacterial-type flagellum-dependent cell motility
EH204_RS07465	COG1256	bacterial-type flagellum assembly
EH204_RS07505	COG1580	Controls the rotational direction of flagella during chemotaxis
EH204_RS07515	COG2882	bacterial-type flagellum organization
EH204_RS07525	COG1317	bacterial-type flagellum organization
EH204_RS07530	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EH204_RS07540	COG1677	Flagellar hook-basal body complex protein FliE
EH204_RS07565	COG0500	methyltransferase
EH204_RS07605	COG1191	sigma factor activity
EH204_RS07615	COG1702	phosphate starvation-inducible protein PhoH
EH204_RS07630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EH204_RS07635	COG1309	transcriptional regulator
EH204_RS07640	COG1012	belongs to the aldehyde dehydrogenase family
EH204_RS07650	COG2979	Protein of unknown function (DUF533)
EH204_RS07655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EH204_RS07660	COG1067	ATP-dependent peptidase activity
EH204_RS07675	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
EH204_RS07680	COG3070	regulator of competence-specific genes
EH204_RS07685	COG1289	transmembrane transporter activity
EH204_RS07690	COG3304	Inner membrane component domain
EH204_RS07695	COG0210	DNA helicase
EH204_RS07700	COG1803	Methylglyoxal synthase
EH204_RS07710	COG1832	CoA-binding protein
EH204_RS07715	COG3785	DNA binding
EH204_RS07720	COG1254	Belongs to the acylphosphatase family
EH204_RS07725	COG2920	part of a sulfur-relay system
EH204_RS07730	COG0670	Belongs to the BI1 family
EH204_RS07760	COG0589	response to stress
EH204_RS07765	COG1683	Conserved Protein
EH204_RS07785	COG0840	transmembrane signaling receptor activity
EH204_RS07800	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EH204_RS07805	COG2943	transferase activity, transferring hexosyl groups
EH204_RS07810	COG1560	Kdo2-lipid A biosynthetic process
EH204_RS07815	COG1902	pentaerythritol trinitrate reductase activity
EH204_RS07825	COG2353	YceI-like domain
EH204_RS07830	COG3038	cytochrome b561
EH204_RS07850	COG0418	dihydroorotase activity
EH204_RS07860	COG1530	ribonuclease E activity
EH204_RS07860	COG1530	ribonuclease E activity
EH204_RS07865	COG0564	pseudouridine synthase activity
EH204_RS07870	COG0424	maF-like protein
EH204_RS07875	COG1399	metal-binding, possibly nucleic acid-binding protein
EH204_RS07880	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EH204_RS07885	COG0416	fatty acid biosynthetic process
EH204_RS07890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EH204_RS07895	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EH204_RS07900	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS07905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH204_RS07910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EH204_RS07915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EH204_RS07920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EH204_RS07925	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EH204_RS07930	COG0470	DNA polymerase III
EH204_RS07935	COG0084	hydrolase, TatD family'
EH204_RS07940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH204_RS07940	COG1263	PTS System
EH204_RS07955	COG0537	adenosine 5'-monophosphoramidase activity
EH204_RS07965	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
EH204_RS07975	COG1472	Belongs to the glycosyl hydrolase 3 family
EH204_RS07980	COG3150	esterase
EH204_RS07985	COG1252	NADH dehydrogenase
EH204_RS07990	COG3134	Outer membrane lipoprotein
EH204_RS07995	COG2814	Major facilitator Superfamily
EH204_RS08005	COG1309	transcriptional regulator
EH204_RS08010	COG0443	Heat shock 70 kDa protein
EH204_RS08020	COG0300	oxidoreductase activity
EH204_RS08030	COG4591	ABC-type transport system involved in lipoprotein release permease component
EH204_RS08035	COG1136	(ABC) transporter
EH204_RS08040	COG4591	ABC-type transport system involved in lipoprotein release permease component
EH204_RS08045	COG1940	carbohydrate kinase activity
EH204_RS08050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EH204_RS08065	COG2226	methyltransferase
EH204_RS08070	COG4139	cobalamin transport
EH204_RS08075	COG0386	Belongs to the glutathione peroxidase family
EH204_RS08080	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EH204_RS08085	COG0791	NLP P60 protein
EH204_RS08090	COG0095	Lipoate-protein ligase
EH204_RS08100	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EH204_RS08105	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EH204_RS08110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH204_RS08115	COG4558	Periplasmic binding protein
EH204_RS08120	COG3720	iron ion transport
EH204_RS08125	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EH204_RS08130	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EH204_RS08135	COG0574	Belongs to the PEP-utilizing enzyme family
EH204_RS08135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EH204_RS08140	COG1477	protein flavinylation
EH204_RS08150	COG0628	permease
EH204_RS08160	COG2050	protein possibly involved in aromatic compounds catabolism
EH204_RS08170	COG0316	Belongs to the HesB IscA family
EH204_RS08175	COG0719	Fe-S assembly protein
EH204_RS08180	COG0396	ATPase activity
EH204_RS08185	COG0719	Fe-S assembly protein
EH204_RS08190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH204_RS08195	COG2166	iron-sulfur cluster assembly
EH204_RS08200	COG1388	LysM domain
EH204_RS08200	COG1376	ErfK ybiS ycfS ynhG family protein
EH204_RS08205	COG4238	major outer membrane lipoprotein
EH204_RS08240	COG2382	esterase
EH204_RS08245	COG1957	nucleoside hydrolase
EH204_RS08250	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EH204_RS08255	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EH204_RS08260	COG0437	4 iron, 4 sulfur cluster binding
EH204_RS08265	COG3301	Polysulphide reductase, NrfD
EH204_RS08270	COG1138	Cytochrome C-type biogenesis protein
EH204_RS08275	COG3088	subunit of a heme lyase
EH204_RS08280	COG4235	cytochrome complex assembly
EH204_RS08285	COG4133	protoheme IX ABC transporter activity
EH204_RS08290	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EH204_RS08295	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EH204_RS08300	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EH204_RS08305	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EH204_RS08310	COG1138	Cytochrome C-type biogenesis protein
EH204_RS08315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EH204_RS08320	COG3088	subunit of a heme lyase
EH204_RS08320	COG4235	cytochrome complex assembly
EH204_RS08325	COG4235	cytochrome complex assembly
EH204_RS08325	COG3088	subunit of a heme lyase
EH204_RS08330	COG3005	denitrification pathway
EH204_RS08335	COG3043	anaerobic respiration
EH204_RS08340	COG0348	domain, Protein
EH204_RS08345	COG0437	4 iron, 4 sulfur cluster binding
EH204_RS08350	COG0243	molybdopterin cofactor binding
EH204_RS08355	COG3062	negative regulation of establishment of protein localization
EH204_RS08360	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH204_RS08360	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH204_RS08365	COG3850	Histidine kinase
EH204_RS08370	COG2197	response regulator
EH204_RS08375	COG0679	Auxin Efflux Carrier
EH204_RS08395	COG1301	dicarboxylic acid transport
EH204_RS08400	COG2076	Multidrug Resistance protein
EH204_RS08405	COG0561	phosphatase activity
EH204_RS08415	COG1408	metallophosphoesterase
EH204_RS08420	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EH204_RS08435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH204_RS08445	COG1116	anion transmembrane transporter activity
EH204_RS08450	COG3665	Urea carboxylase-associated protein
EH204_RS08460	COG0439	Biotin carboxylase
EH204_RS08465	COG1556	Lactate utilization protein
EH204_RS08470	COG1139	Iron-sulfur cluster binding protein
EH204_RS08475	COG0247	lactate metabolic process
EH204_RS08480	COG1620	l-lactate permease
EH204_RS08490	COG0534	Mate efflux family protein
EH204_RS08495	COG0307	riboflavin synthase, alpha
EH204_RS08500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EH204_RS08505	COG1609	Transcriptional regulator
EH204_RS08515	COG0791	NLP P60 protein
EH204_RS08520	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EH204_RS08525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EH204_RS08530	COG0346	lactoylglutathione lyase activity
EH204_RS08535	COG3313	Fe-S protein
EH204_RS08545	COG3133	Outer membrane lipoprotein
EH204_RS08550	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EH204_RS08555	COG3895	Periplasmic Protein
EH204_RS08560	COG0259	pyridoxamine-phosphate oxidase activity
EH204_RS08565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EH204_RS08570	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EH204_RS08575	COG0625	glutathione transferase activity
EH204_RS08580	COG1301	dicarboxylic acid transport
EH204_RS08585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EH204_RS08595	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EH204_RS08600	COG0671	phosphoesterase, PA-phosphatase related
EH204_RS08615	COG1129	ABC transporter
EH204_RS08620	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH204_RS08625	COG3959	Transketolase, thiamine diphosphate binding domain
EH204_RS08630	COG3958	Transketolase
EH204_RS08635	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EH204_RS08640	COG1082	Xylose isomerase domain protein TIM barrel
EH204_RS08650	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EH204_RS08655	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EH204_RS08660	COG0284	orotidine-5'-phosphate decarboxylase activity
EH204_RS08665	COG0023	Translation Initiation Factor
EH204_RS08675	COG0235	Class ii aldolase
EH204_RS08680	COG1966	Carbon starvation protein
EH204_RS08685	COG4989	oxidoreductase activity
EH204_RS08690	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EH204_RS08695	COG0243	molybdopterin cofactor binding
EH204_RS08700	COG0583	DNA-binding transcription factor activity
EH204_RS08705	COG1609	Transcriptional regulator
EH204_RS08710	COG2271	Major facilitator Superfamily
EH204_RS08720	COG1053	succinate dehydrogenase
EH204_RS08750	COG4171	peptide transport system, permease
EH204_RS08755	COG4168	peptide transport system, permease
EH204_RS08760	COG4166	transmembrane transport
EH204_RS08780	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EH204_RS08785	COG1842	Phage shock protein A
EH204_RS08795	COG1983	PspC domain protein
EH204_RS08820	COG2831	hemolysin activation secretion protein
EH204_RS08825	COG3106	COG3106 Predicted ATPase
EH204_RS08830	COG3768	UPF0283 membrane protein
EH204_RS08855	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EH204_RS08860	COG2866	Carboxypeptidase
EH204_RS08865	COG4166	transmembrane transport
EH204_RS08870	COG0598	Magnesium transport protein CorA
EH204_RS08875	COG0037	tRNA processing
EH204_RS08880	COG0582	viral genome integration into host DNA
EH204_RS08950	COG4626	Terminase
EH204_RS08950	COG1802	Transcriptional regulator
EH204_RS08960	COG2974	May be involved in recombination
EH204_RS09150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH204_RS09155	COG0840	transmembrane signaling receptor activity
EH204_RS09160	COG0840	transmembrane signaling receptor activity
EH204_RS09165	COG2911	Protein conserved in bacteria
EH204_RS09175	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EH204_RS09180	COG1643	Atp-dependent helicase
EH204_RS09190	COG3300	MHYT domain
EH204_RS09190	COG5001	Diguanylate cyclase
EH204_RS09195	COG3591	Belongs to the peptidase S1B family
EH204_RS09210	COG2205	protein histidine kinase activity
EH204_RS09215	COG0745	RESPONSE REGULATOR receiver
EH204_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS09250	COG0659	secondary active sulfate transmembrane transporter activity
EH204_RS09255	COG0387	Pfam Sodium calcium exchanger
EH204_RS09265	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EH204_RS09285	COG2197	response regulator
EH204_RS09290	COG3850	Histidine kinase
EH204_RS09295	COG2223	nitrite transmembrane transporter activity
EH204_RS09300	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EH204_RS09305	COG1140	nitrate reductase beta subunit
EH204_RS09310	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EH204_RS09315	COG2181	nitrate reductase activity
EH204_RS09320	COG3547	Transposase (IS116 IS110 IS902 family)
EH204_RS09325	COG0697	spore germination
EH204_RS09330	COG1846	Transcriptional regulator
EH204_RS09360	COG5290	Psort location Cytoplasmic, score
EH204_RS09365	COG2261	transglycosylase associated protein
EH204_RS09370	COG2255	four-way junction helicase activity
EH204_RS09380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EH204_RS09395	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS09400	COG3842	ATPase activity
EH204_RS09410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EH204_RS09415	COG1012	belongs to the aldehyde dehydrogenase family
EH204_RS09430	COG1176	ABC-type spermidine putrescine transport system, permease component I
EH204_RS09440	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS09450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EH204_RS09460	COG0671	phosphoesterase, PA-phosphatase related
EH204_RS09465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EH204_RS09470	COG2011	ABC-type metal ion transport system permease component
EH204_RS09475	COG4948	Mandelate Racemase Muconate Lactonizing
EH204_RS09480	COG1464	Belongs to the NlpA lipoprotein family
EH204_RS09490	COG0583	DNA-binding transcription factor activity
EH204_RS09495	COG4792	protein secretion
EH204_RS09505	COG4794	Type iii secretion
EH204_RS09530	COG1157	protein secretion by the type III secretion system
EH204_RS09560	COG2197	response regulator
EH204_RS09570	COG2200	EAL domain
EH204_RS09650	COG1802	Transcriptional regulator
EH204_RS09670	COG3210	domain, Protein
EH204_RS09675	COG3210	domain, Protein
EH204_RS09755	COG1802	Transcriptional regulator
EH204_RS09765	COG0559	Belongs to the binding-protein-dependent transport system permease family
EH204_RS09775	COG0411	ABC transporter
EH204_RS09790	COG0640	Transcriptional regulator
EH204_RS09795	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EH204_RS09805	COG1126	abc transporter atp-binding protein
EH204_RS09810	COG0765	amino acid transport
EH204_RS09820	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EH204_RS09830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH204_RS09845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH204_RS09855	COG2234	aminopeptidase activity
EH204_RS09860	COG1609	Transcriptional regulator
EH204_RS09865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH204_RS09865	COG1263	PTS System
EH204_RS09870	COG2723	6-phospho-beta-galactosidase activity
EH204_RS09875	COG0483	inositol monophosphate 1-phosphatase activity
EH204_RS09880	COG0346	lactoylglutathione lyase activity
EH204_RS09890	COG0523	cobalamin synthesis protein
EH204_RS09915	COG0583	DNA-binding transcription factor activity
EH204_RS09925	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EH204_RS09930	COG0012	GTP binding
EH204_RS09935	COG0193	aminoacyl-tRNA hydrolase activity
EH204_RS09945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EH204_RS09950	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EH204_RS09955	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EH204_RS09960	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EH204_RS09965	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EH204_RS09970	COG2890	protein-(glutamine-N5) methyltransferase activity
EH204_RS09975	COG3094	Invasion gene expression up-regulator, SirB
EH204_RS09980	COG2912	Transglutaminase-like superfamily
EH204_RS09985	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EH204_RS09995	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EH204_RS10000	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EH204_RS10010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH204_RS10015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EH204_RS10020	COG0673	inositol 2-dehydrogenase activity
EH204_RS10050	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS10075	COG4305	rare lipoprotein A
EH204_RS10080	COG1764	response to oxidative stress
EH204_RS10085	COG3783	Cytochrome b(562)
EH204_RS10095	COG0738	Major facilitator superfamily
EH204_RS10100	COG0456	acetyltransferase
EH204_RS10135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EH204_RS10140	COG4628	conserved protein (DUF2132)
EH204_RS10160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EH204_RS10165	COG0076	glutamate decarboxylase activity
EH204_RS10170	COG1942	4-Oxalocrotonate Tautomerase
EH204_RS10190	COG1215	transferase activity, transferring glycosyl groups
EH204_RS10195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EH204_RS10200	COG4221	oxidoreductase activity
EH204_RS10230	COG0477	Major facilitator Superfamily
EH204_RS10235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EH204_RS10240	COG1940	carbohydrate kinase activity
EH204_RS10245	COG0583	DNA-binding transcription factor activity
EH204_RS10250	COG2814	Major facilitator Superfamily
EH204_RS10260	COG0114	fumarate hydratase activity
EH204_RS10265	COG1482	cell wall glycoprotein biosynthetic process
EH204_RS10270	COG5339	Protein conserved in bacteria
EH204_RS10280	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EH204_RS10290	COG0385	Bile acid
EH204_RS10295	COG0673	inositol 2-dehydrogenase activity
EH204_RS10305	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH204_RS10310	COG1129	ABC transporter
EH204_RS10315	COG1879	ABC-type sugar transport system periplasmic component
EH204_RS10325	COG2160	L-arabinose isomerase activity
EH204_RS10335	COG4657	Part of a membrane complex involved in electron transport
EH204_RS10340	COG2878	Part of a membrane complex involved in electron transport
EH204_RS10350	COG4658	electron transport chain
EH204_RS10355	COG4659	FMN binding
EH204_RS10365	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EH204_RS10370	COG3104	oligopeptide transport
EH204_RS10380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EH204_RS10390	COG0616	signal peptide processing
EH204_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS10400	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EH204_RS10405	COG1187	pseudouridine synthase activity
EH204_RS10410	COG0009	L-threonylcarbamoyladenylate synthase
EH204_RS10415	COG0613	PHP domain protein
EH204_RS10425	COG0512	Glutamine amidotransferase of anthranilate synthase
EH204_RS10430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EH204_RS10435	COG0135	phosphoribosylanthranilate isomerase activity
EH204_RS10435	COG0134	indole-3-glycerol-phosphate synthase activity
EH204_RS10440	COG0133	tryptophan synthase activity
EH204_RS10445	COG0159	tryptophan synthase activity
EH204_RS10450	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EH204_RS10455	COG3047	cAMP biosynthetic process
EH204_RS10465	COG2917	probably involved in intracellular septation
EH204_RS10470	COG1607	acyl-coa hydrolase
EH204_RS10480	COG2350	Protein conserved in bacteria
EH204_RS10495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH204_RS10500	COG3099	Belongs to the UPF0263 family
EH204_RS10510	COG0444	Belongs to the ABC transporter superfamily
EH204_RS10515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH204_RS10520	COG0601	transmembrane transport
EH204_RS10540	COG1435	thymidine kinase activity
EH204_RS10550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EH204_RS10555	COG0745	RESPONSE REGULATOR receiver
EH204_RS10560	COG1752	Esterase of the alpha-beta hydrolase superfamily
EH204_RS10565	COG3012	SEC-C Motif Domain Protein
EH204_RS10570	COG0788	formyltetrahydrofolate deformylase activity
EH204_RS10585	COG2860	membrane
EH204_RS10590	COG0708	Exodeoxyribonuclease III
EH204_RS10600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EH204_RS10605	COG0778	Nitroreductase
EH204_RS10610	COG0616	signal peptide processing
EH204_RS10615	COG0252	asparaginase activity
EH204_RS10620	COG1335	isochorismatase
EH204_RS10625	COG3139	Protein of unknown function (DUF1315)
EH204_RS10630	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EH204_RS10645	COG0656	L-ascorbic acid biosynthetic process
EH204_RS10650	COG3713	MltA-interacting MipA family protein
EH204_RS10655	COG2766	serine protein kinase
EH204_RS10660	COG2718	Belongs to the UPF0229 family
EH204_RS10675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EH204_RS10680	COG0205	6-phosphofructokinase activity
EH204_RS10710	COG3684	Belongs to the aldolase LacD family
EH204_RS10715	COG2719	SpoVR family
EH204_RS10720	COG2186	Transcriptional regulator
EH204_RS10725	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EH204_RS10730	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EH204_RS10745	COG2983	Belongs to the UPF0260 family
EH204_RS10750	COG0179	Fumarylacetoacetate (FAA) hydrolase
EH204_RS10755	COG3100	YcgL domain-containing protein
EH204_RS10760	COG0850	regulation of cytokinetic process
EH204_RS10765	COG2894	cell division
EH204_RS10770	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EH204_RS10775	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EH204_RS10780	COG0318	PFAM AMP-dependent synthetase and ligase
EH204_RS10785	COG3065	identical protein binding
EH204_RS10795	COG1199	ATP-dependent helicase activity
EH204_RS10800	COG0251	oxidation-reduction process
EH204_RS10805	COG3140	Belongs to the UPF0181 family
EH204_RS10815	COG0494	nUDIX hydrolase
EH204_RS10820	COG1760	l-serine dehydratase
EH204_RS10825	COG1253	flavin adenine dinucleotide binding
EH204_RS10830	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH204_RS10830	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH204_RS10835	COG3715	PTS system
EH204_RS10840	COG3716	PTS system mannose fructose sorbose family IID component
EH204_RS10845	COG4811	Protein of unknown function (DUF986)
EH204_RS10850	COG1971	Probably functions as a manganese efflux pump
EH204_RS10855	COG2226	methyltransferase
EH204_RS10860	COG1278	Cold shock
EH204_RS10870	COG0803	Belongs to the bacterial solute-binding protein 9 family
EH204_RS10875	COG1121	(ABC) transporter
EH204_RS10880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH204_RS10885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH204_RS10900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH204_RS10905	COG1917	Cupin 2, conserved barrel domain protein
EH204_RS10915	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS10925	COG1175	transmembrane transport
EH204_RS10930	COG0395	ABC-type sugar transport system, permease component
EH204_RS10935	COG3842	ATPase activity
EH204_RS10945	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EH204_RS10950	COG0657	acetylesterase activity
EH204_RS10950	COG2755	lipolytic protein G-D-S-L family
EH204_RS10955	COG1988	membrane-bound metal-dependent
EH204_RS10965	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH204_RS10970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EH204_RS10980	COG1132	(ABC) transporter
EH204_RS10990	COG0776	regulation of translation
EH204_RS10995	COG0072	phenylalanine-tRNA ligase activity
EH204_RS10995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH204_RS11000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EH204_RS11010	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EH204_RS11015	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EH204_RS11020	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EH204_RS11025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EH204_RS11030	COG1113	amino acid transport
EH204_RS11045	COG0823	Involved in the tonB-independent uptake of proteins
EH204_RS11050	COG0501	Belongs to the peptidase M48B family
EH204_RS11060	COG1653	transport
EH204_RS11070	COG3279	Response regulator of the LytR AlgR family
EH204_RS11075	COG3275	phosphorelay sensor kinase activity
EH204_RS11080	COG3300	MHYT domain
EH204_RS11080	COG5001	Diguanylate cyclase
EH204_RS11100	COG0348	domain, Protein
EH204_RS11115	COG0538	isocitrate dehydrogenase activity
EH204_RS11120	COG1187	pseudouridine synthase activity
EH204_RS11130	COG0482	sulfurtransferase activity
EH204_RS11135	COG2915	High frequency lysogenization protein hflD homolog
EH204_RS11140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EH204_RS11145	COG0745	RESPONSE REGULATOR receiver
EH204_RS11150	COG2205	protein histidine kinase activity
EH204_RS11155	COG2850	peptidyl-arginine hydroxylation
EH204_RS11160	COG2195	Cleaves the N-terminal amino acid of tripeptides
EH204_RS11165	COG3842	ATPase activity
EH204_RS11170	COG1176	ABC-type spermidine putrescine transport system, permease component I
EH204_RS11175	COG1177	transmembrane transport
EH204_RS11180	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EH204_RS11190	COG2207	Transcriptional regulator
EH204_RS11200	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EH204_RS11205	COG1956	GAF domain-containing protein
EH204_RS11215	COG3008	intermembrane lipid transfer
EH204_RS11220	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EH204_RS11220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EH204_RS11235	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EH204_RS11245	COG1278	Cold shock
EH204_RS11410	COG3772	lysozyme
EH204_RS11465	COG3756	Protein conserved in bacteria
EH204_RS11505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EH204_RS11530	COG1528	Iron-storage protein
EH204_RS11545	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EH204_RS11550	COG0800	Aldolase
EH204_RS11555	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EH204_RS11560	COG1737	Transcriptional regulator
EH204_RS11565	COG0469	pyruvate kinase activity
EH204_RS11575	COG0739	heme binding
EH204_RS11580	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EH204_RS11585	COG1121	(ABC) transporter
EH204_RS11590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH204_RS11595	COG1609	Transcriptional regulator
EH204_RS11600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH204_RS11605	COG1447	Phosphotransferase system cellobiose-specific component IIA
EH204_RS11610	COG4580	involved in the transport of maltose and maltodextrins
EH204_RS11615	COG2255	four-way junction helicase activity
EH204_RS11620	COG0632	four-way junction helicase activity
EH204_RS11625	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EH204_RS11630	COG0217	transcriptional regulatory protein
EH204_RS11635	COG0494	nUDIX hydrolase
EH204_RS11640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EH204_RS11645	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EH204_RS11650	COG1801	Protein of unknown function DUF72
EH204_RS11655	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EH204_RS11660	COG2226	methyltransferase
EH204_RS11665	COG0500	methyltransferase
EH204_RS11670	COG3142	Participates in the control of copper homeostasis
EH204_RS11675	COG3102	Protein conserved in bacteria
EH204_RS11680	COG0018	arginyl-trna synthetase
EH204_RS11695	COG3132	Protein of unknown function, DUF480
EH204_RS11700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH204_RS11705	COG0477	Major facilitator Superfamily
EH204_RS11710	COG2999	glutathione oxidoreductase activity
EH204_RS11720	COG3381	protein complex oligomerization
EH204_RS11725	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EH204_RS11735	COG0840	transmembrane signaling receptor activity
EH204_RS11740	COG3130	regulation of translation
EH204_RS11745	COG3009	Protein conserved in bacteria
EH204_RS11750	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EH204_RS11750	COG3008	intermembrane lipid transfer
EH204_RS11755	COG2995	paraquat-inducible protein a
EH204_RS11760	COG0488	(ABC) transporter
EH204_RS11765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EH204_RS11765	COG0116	Belongs to the methyltransferase superfamily
EH204_RS11770	COG0633	Ferredoxin
EH204_RS11770	COG3217	Mosc domain protein beta barrel domain protein
EH204_RS11780	COG0167	dihydroorotate dehydrogenase activity
EH204_RS11785	COG0308	aminopeptidase N
EH204_RS11790	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EH204_RS11795	COG0017	Asparaginyl-tRNA synthetase
EH204_RS11805	COG1448	Aminotransferase
EH204_RS11810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EH204_RS11815	COG3108	Peptidase M15
EH204_RS11820	COG2989	Protein conserved in bacteria
EH204_RS11825	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EH204_RS11830	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EH204_RS11835	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EH204_RS11840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EH204_RS11845	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EH204_RS11850	COG3173	Aminoglycoside phosphotransferase
EH204_RS11865	COG2835	tetraacyldisaccharide 4'-kinase activity
EH204_RS11870	COG1663	tetraacyldisaccharide 4'-kinase activity
EH204_RS11875	COG1132	(ABC) transporter
EH204_RS11880	COG2333	competence protein COMEC
EH204_RS11880	COG0658	competence protein
EH204_RS11885	COG2926	Belongs to the UPF0265 family
EH204_RS11890	COG4604	ABC transporter, ATP-binding protein
EH204_RS11895	COG4605	iron ion homeostasis
EH204_RS11910	COG2925	Exonuclease
EH204_RS11915	COG0531	amino acid
EH204_RS11925	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EH204_RS11950	COG3052	prosthetic group binding
EH204_RS11955	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EH204_RS11960	COG0179	Fumarylacetoacetate (FAA) hydrolase
EH204_RS11965	COG3493	citrate carrier protein
EH204_RS11975	COG4565	transcriptional regulatory protein
EH204_RS11980	COG0840	transmembrane signaling receptor activity
EH204_RS11985	COG0840	transmembrane signaling receptor activity
EH204_RS11990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH204_RS12000	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EH204_RS12005	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EH204_RS12010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EH204_RS12015	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EH204_RS12015	COG0131	Imidazoleglycerol-phosphate dehydratase
EH204_RS12020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EH204_RS12025	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EH204_RS12030	COG0107	imidazoleglycerol-phosphate synthase activity
EH204_RS12035	COG0140	phosphoribosyl-ATP diphosphatase activity
EH204_RS12035	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EH204_RS12045	COG0776	regulation of translation
EH204_RS12050	COG0539	negative regulation of cytoplasmic translation
EH204_RS12055	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EH204_RS12060	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EH204_RS12065	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EH204_RS12070	COG1944	ATP diphosphatase activity
EH204_RS12075	COG2116	formate transmembrane transporter activity
EH204_RS12080	COG1882	Formate acetyltransferase
EH204_RS12085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EH204_RS12110	COG2814	Major facilitator Superfamily
EH204_RS12115	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EH204_RS12120	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EH204_RS12125	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EH204_RS12130	COG1674	ftsk spoiiie
EH204_RS12130	COG3107	peptidoglycan biosynthetic process
EH204_RS12140	COG0492	ferredoxin-NADP+ reductase activity
EH204_RS12145	COG4988	ABC transporter
EH204_RS12150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EH204_RS12155	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EH204_RS12160	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EH204_RS12170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EH204_RS12175	COG0542	response to heat
EH204_RS12180	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EH204_RS12185	COG1278	Cold shock
EH204_RS12190	COG3593	DNA synthesis involved in DNA repair
EH204_RS12195	COG2431	L-lysine efflux transmembrane transporter activity
EH204_RS12200	COG1151	hydroxylamine reductase activity
EH204_RS12205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH204_RS12210	COG0702	epimerase
EH204_RS12215	COG3023	N-Acetylmuramoyl-L-alanine amidase
EH204_RS12220	COG0393	Putative heavy-metal-binding
EH204_RS12225	COG1126	abc transporter atp-binding protein
EH204_RS12230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH204_RS12235	COG4215	(ABC) transporter
EH204_RS12240	COG4160	amino acid transport
EH204_RS12245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH204_RS12250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EH204_RS12260	COG1177	transmembrane transport
EH204_RS12265	COG1176	ABC-type spermidine putrescine transport system, permease component I
EH204_RS12270	COG3842	ATPase activity
EH204_RS12275	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EH204_RS12285	COG0189	ligase activity
EH204_RS12290	COG0778	Nitroreductase
EH204_RS12295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EH204_RS12305	COG2985	domain, Protein
EH204_RS12305	COG0569	domain protein
EH204_RS12310	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EH204_RS12315	COG1349	DNA-binding transcription factor activity
EH204_RS12320	COG1686	Belongs to the peptidase S11 family
EH204_RS12325	COG2011	ABC-type metal ion transport system permease component
EH204_RS12330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EH204_RS12340	COG0625	glutathione transferase activity
EH204_RS12345	COG2133	pyrroloquinoline quinone binding
EH204_RS12350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH204_RS12355	COG2949	membrane
EH204_RS12360	COG2311	Membrane
EH204_RS12365	COG0302	gtp cyclohydrolase
EH204_RS12375	COG0583	DNA-binding transcription factor activity
EH204_RS12400	COG0371	Dehydrogenase
EH204_RS12405	COG1129	ABC transporter
EH204_RS12410	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH204_RS12415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH204_RS12420	COG4771	TonB-dependent receptor
EH204_RS12425	COG0833	amino acid
EH204_RS12430	COG0583	DNA-binding transcription factor activity
EH204_RS12435	COG2855	membrane
EH204_RS12440	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EH204_RS12445	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EH204_RS12445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH204_RS12445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH204_RS12450	COG1105	Belongs to the carbohydrate kinase PfkB family
EH204_RS12455	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH204_RS12455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH204_RS12470	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EH204_RS12475	COG0523	cobalamin synthesis protein
EH204_RS12480	COG0671	phosphoesterase, PA-phosphatase related
EH204_RS12485	COG0791	NLP P60 protein
EH204_RS12500	COG0625	glutathione transferase activity
EH204_RS12505	COG4166	transmembrane transport
EH204_RS12510	COG4174	ABC transporter (Permease)
EH204_RS12515	COG4239	(ABC) transporter, permease
EH204_RS12520	COG4172	Belongs to the ABC transporter superfamily
EH204_RS12530	COG2814	Major facilitator Superfamily
EH204_RS12535	COG1187	pseudouridine synthase activity
EH204_RS12545	COG1061	Type III restriction enzyme res subunit
EH204_RS12550	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EH204_RS12560	COG3081	Nucleoid-associated protein
EH204_RS12565	COG3082	Protein of unknown function (DUF1414)
EH204_RS12570	COG3083	sulfuric ester hydrolase activity
EH204_RS12600	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EH204_RS12615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH204_RS12620	COG0534	Mate efflux family protein
EH204_RS12625	COG2807	transmembrane transport
EH204_RS12630	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EH204_RS12645	COG0783	Belongs to the Dps family
EH204_RS12650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH204_RS12655	COG0765	amino acid transport
EH204_RS12660	COG1126	abc transporter atp-binding protein
EH204_RS12670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EH204_RS12740	COG0633	Ferredoxin
EH204_RS12830	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EH204_RS12845	COG1686	Belongs to the peptidase S11 family
EH204_RS12870	COG2040	homocysteine
EH204_RS12875	COG0833	amino acid
EH204_RS12880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EH204_RS12885	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EH204_RS12890	COG0747	negative chemotaxis
EH204_RS12895	COG2195	Cleaves the N-terminal amino acid of tripeptides
EH204_RS12900	COG2207	Transcriptional regulator
EH204_RS12900	COG3708	Transcriptional regulator
EH204_RS12910	COG0513	Belongs to the DEAD box helicase family
EH204_RS12920	COG1120	ATPase activity
EH204_RS12925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH204_RS12930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH204_RS12935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH204_RS12950	COG1131	(ABC) transporter
EH204_RS12955	COG0842	Transport permease protein
EH204_RS12960	COG0842	Transport permease protein
EH204_RS12970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH204_RS12975	COG1136	(ABC) transporter
EH204_RS12975	COG0577	efflux transmembrane transporter activity
EH204_RS12980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EH204_RS12985	COG0670	Belongs to the BI1 family
EH204_RS12990	COG0314	molybdopterin synthase activity
EH204_RS12995	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EH204_RS13000	COG0315	cyclic pyranopterin monophosphate synthase activity
EH204_RS13005	COG0521	Mo-molybdopterin cofactor biosynthetic process
EH204_RS13010	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EH204_RS13025	COG0556	nucleotide-excision repair
EH204_RS13045	COG3157	Type VI secretion system effector, Hcp
EH204_RS13050	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EH204_RS13055	COG2226	methyltransferase
EH204_RS13060	COG0156	8-amino-7-oxononanoate synthase activity
EH204_RS13065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EH204_RS13075	COG5297	Belongs to the glycosyl hydrolase family 6
EH204_RS13080	COG1380	Effector of murein hydrolase LrgA
EH204_RS13085	COG1346	cytolysis
EH204_RS13090	COG0295	cytidine deaminase activity
EH204_RS13095	COG0281	malic enzyme
EH204_RS13100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH204_RS13105	COG0601	transmembrane transport
EH204_RS13110	COG0747	negative chemotaxis
EH204_RS13115	COG4172	Belongs to the ABC transporter superfamily
EH204_RS13120	COG0303	'Molybdopterin
EH204_RS13125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EH204_RS13140	COG3706	GGDEF domain
EH204_RS13155	COG0471	metal ion transport
EH204_RS13160	COG0401	homolog of Blt101
EH204_RS13180	COG3228	Belongs to the MtfA family
EH204_RS13190	COG0582	viral genome integration into host DNA
EH204_RS13245	COG0210	DNA helicase
EH204_RS13380	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EH204_RS13395	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EH204_RS13405	COG2199	diguanylate cyclase activity
EH204_RS13410	COG3122	Protein conserved in bacteria
EH204_RS13420	COG2723	6-phospho-beta-galactosidase activity
EH204_RS13435	COG2814	Major facilitator Superfamily
EH204_RS13455	COG1733	regulation of RNA biosynthetic process
EH204_RS13460	COG0640	Transcriptional regulator
EH204_RS13470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EH204_RS13480	COG1733	regulation of RNA biosynthetic process
EH204_RS13485	COG2910	NAD(P)H-binding
EH204_RS13490	COG0625	glutathione transferase activity
EH204_RS13495	COG0835	chemotaxis
EH204_RS13495	COG0784	Response regulator, receiver
EH204_RS13510	COG2995	paraquat-inducible protein a
EH204_RS13515	COG3008	intermembrane lipid transfer
EH204_RS13515	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EH204_RS13520	COG3009	Protein conserved in bacteria
EH204_RS13535	COG1132	(ABC) transporter
EH204_RS13555	COG4771	TonB-dependent receptor
EH204_RS13575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH204_RS13595	COG4172	Belongs to the ABC transporter superfamily
EH204_RS13610	COG0747	negative chemotaxis
EH204_RS13615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH204_RS13635	COG0477	Major facilitator Superfamily
EH204_RS13645	COG2226	methyltransferase
EH204_RS13650	COG0840	transmembrane signaling receptor activity
EH204_RS13655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EH204_RS13660	COG1012	belongs to the aldehyde dehydrogenase family
EH204_RS13700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EH204_RS13710	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EH204_RS13715	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EH204_RS13720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH204_RS13745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH204_RS13750	COG0371	Dehydrogenase
EH204_RS13755	COG1301	dicarboxylic acid transport
EH204_RS13770	COG0697	spore germination
EH204_RS13775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EH204_RS13780	COG0577	efflux transmembrane transporter activity
EH204_RS13780	COG1136	(ABC) transporter
EH204_RS13790	COG0577	efflux transmembrane transporter activity
EH204_RS13790	COG1136	(ABC) transporter
EH204_RS13805	COG0672	)-iron permease
EH204_RS13810	COG0840	transmembrane signaling receptor activity
EH204_RS13815	COG3383	formate dehydrogenase (NAD+) activity
EH204_RS13820	COG2851	Citrate transporter
EH204_RS13830	COG1301	dicarboxylic acid transport
EH204_RS13835	COG0583	DNA-binding transcription factor activity
EH204_RS13850	COG1464	Belongs to the NlpA lipoprotein family
EH204_RS13870	COG1840	ABC-type Fe3 transport system, periplasmic component
EH204_RS13880	COG3842	ATPase activity
EH204_RS13885	COG1609	Transcriptional regulator
EH204_RS13890	COG3250	beta-galactosidase activity
EH204_RS13895	COG2223	nitrite transmembrane transporter activity
EH204_RS13910	COG2814	Major facilitator Superfamily
EH204_RS13940	COG0659	secondary active sulfate transmembrane transporter activity
EH204_RS13950	COG4948	Mandelate Racemase Muconate Lactonizing
EH204_RS13970	COG0745	RESPONSE REGULATOR receiver
EH204_RS13975	COG5000	phosphorelay sensor kinase activity
EH204_RS13975	COG5002	protein histidine kinase activity
EH204_RS13990	COG0765	amino acid transport
EH204_RS13995	COG0765	amino acid transport
EH204_RS14015	COG0745	RESPONSE REGULATOR receiver
EH204_RS14025	COG1403	HNH endonuclease
EH204_RS14040	COG0626	cystathionine gamma-synthase activity
EH204_RS14045	COG1902	pentaerythritol trinitrate reductase activity
EH204_RS14050	COG0640	Transcriptional regulator
EH204_RS14055	COG1070	Carbohydrate kinase
EH204_RS14060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH204_RS14070	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH204_RS14075	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH204_RS14080	COG1129	ABC transporter
EH204_RS14090	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EH204_RS14095	COG4807	Protein conserved in bacteria
EH204_RS14105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EH204_RS14105	COG1648	precorrin-2 dehydrogenase activity
EH204_RS14110	COG0243	molybdopterin cofactor binding
EH204_RS14115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EH204_RS14115	COG2146	nitrite reductase [NAD(P)H] activity
EH204_RS14120	COG1116	anion transmembrane transporter activity
EH204_RS14130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH204_RS14135	COG3707	response regulator
EH204_RS14150	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EH204_RS14155	COG1271	oxidase subunit
EH204_RS14160	COG1294	oxidase, subunit
EH204_RS14165	COG4890	Cyd operon protein YbgT
EH204_RS14170	COG2149	membrane
EH204_RS14180	COG3058	Necessary for formate dehydrogenase activity
EH204_RS14185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH204_RS14190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EH204_RS14190	COG0519	Catalyzes the synthesis of GMP from XMP
EH204_RS14215	COG4771	TonB-dependent receptor
EH204_RS14225	COG0488	(ABC) transporter
EH204_RS14240	COG1263	PTS System
EH204_RS14240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH204_RS14245	COG0366	Alpha amylase catalytic
EH204_RS14250	COG4575	ribosome binding
EH204_RS14255	COG1007	ATP synthesis coupled electron transport
EH204_RS14260	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH204_RS14265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EH204_RS14270	COG0713	ATP synthesis coupled electron transport
EH204_RS14275	COG0839	Belongs to the complex I subunit 6 family
EH204_RS14280	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH204_RS14285	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EH204_RS14290	COG1034	ATP synthesis coupled electron transport
EH204_RS14300	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EH204_RS14305	COG0649	NAD binding
EH204_RS14305	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH204_RS14310	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH204_RS14320	COG0583	DNA-binding transcription factor activity
EH204_RS14325	COG0436	Aminotransferase
EH204_RS14330	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EH204_RS14335	COG0490	domain, Protein
EH204_RS14335	COG0471	metal ion transport
EH204_RS14340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH204_RS14345	COG3013	Belongs to the UPF0304 family
EH204_RS14350	COG3092	negative regulation of chromosome organization
EH204_RS14355	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EH204_RS14360	COG0280	phosphate acetyltransferase
EH204_RS14360	COG0857	belongs to the CobB CobQ family
EH204_RS14370	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EH204_RS14375	COG0622	Phosphoesterase
EH204_RS14380	COG0625	glutathione transferase activity
EH204_RS14385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EH204_RS14390	COG1090	epimerase
EH204_RS14395	COG4598	ABC transporter
EH204_RS14400	COG4160	amino acid transport
EH204_RS14405	COG4215	(ABC) transporter
EH204_RS14420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EH204_RS14425	COG1286	toxin biosynthetic process
EH204_RS14430	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EH204_RS14435	COG0285	dihydrofolate synthase activity
EH204_RS14440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EH204_RS14450	COG0586	Pfam SNARE associated Golgi protein
EH204_RS14455	COG0101	tRNA pseudouridine synthase activity
EH204_RS14460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EH204_RS14465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH204_RS14470	COG0697	spore germination
EH204_RS14480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EH204_RS14485	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EH204_RS14485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EH204_RS14495	COG3101	peptidyl-lysine hydroxylation
EH204_RS14500	COG0730	response to heat
EH204_RS14505	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
EH204_RS14510	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EH204_RS14515	COG2890	protein-(glutamine-N5) methyltransferase activity
EH204_RS14520	COG2840	Smr protein MutS2
EH204_RS14525	COG2062	phosphohistidine phosphatase, SixA
EH204_RS14545	COG3188	usher protein
EH204_RS14555	COG1250	3-hydroxyacyl-CoA dehydrogenase
EH204_RS14555	COG1024	Enoyl-CoA hydratase
EH204_RS14565	COG3691	Protein conserved in bacteria
EH204_RS14570	COG2067	long-chain fatty acid transport protein
EH204_RS14575	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS14580	COG0583	DNA-binding transcription factor activity
EH204_RS14595	COG2116	formate transmembrane transporter activity
EH204_RS14670	COG0513	Belongs to the DEAD box helicase family
EH204_RS14695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH204_RS14775	COG3866	Pectate lyase
EH204_RS14780	COG3266	domain, Protein
EH204_RS14790	COG0436	Aminotransferase
EH204_RS14825	COG3267	Type II secretory pathway component ExeA
EH204_RS14825	COG3409	Peptidoglycan-binding domain 1 protein
EH204_RS14880	COG0741	lytic transglycosylase activity
EH204_RS14905	COG4373	Mu-like prophage FluMu protein gp28
EH204_RS14915	COG2369	cell adhesion
EH204_RS15035	COG4948	Mandelate Racemase Muconate Lactonizing
EH204_RS15040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EH204_RS15045	COG1511	domain protein
EH204_RS15045	COG3264	Mechanosensitive ion channel
EH204_RS15060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH204_RS15075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH204_RS15080	COG1696	Membrane protein involved in D-alanine export
EH204_RS15105	COG1447	Phosphotransferase system cellobiose-specific component IIA
EH204_RS15120	COG3842	ATPase activity
EH204_RS15125	COG2076	Multidrug Resistance protein
EH204_RS15130	COG2076	Multidrug Resistance protein
EH204_RS15135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EH204_RS15140	COG0726	polysaccharide deacetylase
EH204_RS15145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EH204_RS15145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH204_RS15150	COG0463	Glycosyl transferase, family 2
EH204_RS15155	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EH204_RS15165	COG4251	negative regulation of phosphorylation
EH204_RS15165	COG5001	Diguanylate cyclase
EH204_RS15165	COG2203	Gaf domain
EH204_RS15165	COG3706	GGDEF domain
EH204_RS15170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EH204_RS15175	COG2501	S4 domain
EH204_RS15180	COG0215	cysteine-tRNA ligase activity
EH204_RS15190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EH204_RS15195	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH204_RS15200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EH204_RS15205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EH204_RS15210	COG0814	amino acid
EH204_RS15215	COG1760	l-serine dehydratase
EH204_RS15235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EH204_RS15240	COG0581	inorganic phosphate transmembrane transporter activity
EH204_RS15250	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EH204_RS15255	COG0248	Ppx GppA phosphatase
EH204_RS15270	COG1764	response to oxidative stress
EH204_RS15275	COG1846	Transcriptional regulator
EH204_RS15280	COG2239	Acts as a magnesium transporter
EH204_RS15295	COG1609	Transcriptional regulator
EH204_RS15300	COG4580	involved in the transport of maltose and maltodextrins
EH204_RS15305	COG3842	ATPase activity
EH204_RS15310	COG2182	Extracellular solute-binding protein
EH204_RS15315	COG1175	transmembrane transport
EH204_RS15320	COG3833	ABC-type maltose transport systems, permease component
EH204_RS15325	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EH204_RS15330	COG1874	Beta-galactosidase
EH204_RS15345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EH204_RS15350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH204_RS15355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH204_RS15360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH204_RS15365	COG0477	Major facilitator Superfamily
EH204_RS15370	COG2205	protein histidine kinase activity
EH204_RS15375	COG0745	RESPONSE REGULATOR receiver
EH204_RS15390	COG0435	Glutathione S-transferase
EH204_RS15400	COG1597	lipid kinase activity
EH204_RS15405	COG3223	Belongs to the PsiE family
EH204_RS15415	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EH204_RS15420	COG1064	alcohol dehydrogenase
EH204_RS15425	COG5001	Diguanylate cyclase
EH204_RS15475	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EH204_RS15500	COG3423	Transcriptional regulator
EH204_RS15520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EH204_RS15520	COG0519	Catalyzes the synthesis of GMP from XMP
EH204_RS15525	COG0517	IMP dehydrogenase activity
EH204_RS15525	COG0516	GMP reductase activity
EH204_RS15530	COG1570	exodeoxyribonuclease VII activity
EH204_RS15545	COG1645	bacterial-type flagellum-dependent swarming motility
EH204_RS15560	COG1160	GTP binding
EH204_RS15565	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH204_RS15570	COG2976	Protein conserved in bacteria
EH204_RS15575	COG0124	histidyl-tRNA synthetase
EH204_RS15580	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EH204_RS15585	COG1426	Protein conserved in bacteria
EH204_RS15595	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EH204_RS15600	COG0105	UTP biosynthetic process
EH204_RS15605	COG1263	PTS System
EH204_RS15605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH204_RS15605	COG2190	(PTS) system
EH204_RS15610	COG1486	melibiose metabolic process
EH204_RS15615	COG2897	thiosulfate sulfurtransferase activity
EH204_RS15630	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EH204_RS15635	COG2975	iron-sulfur cluster assembly
EH204_RS15640	COG0633	Ferredoxin
EH204_RS15645	COG0443	Heat shock 70 kDa protein
EH204_RS15650	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EH204_RS15655	COG0316	Belongs to the HesB IscA family
EH204_RS15660	COG0822	iron-sulfur transferase activity
EH204_RS15665	COG1104	cysteine desulfurase activity
EH204_RS15670	COG1959	2 iron, 2 sulfur cluster binding
EH204_RS15675	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EH204_RS15680	COG0483	inositol monophosphate 1-phosphatase activity
EH204_RS15690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH204_RS15695	COG1120	ATPase activity
EH204_RS15705	COG0840	transmembrane signaling receptor activity
EH204_RS15715	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EH204_RS15720	COG3683	transport system, periplasmic component
EH204_RS15725	COG2814	Major facilitator Superfamily
EH204_RS15730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EH204_RS15735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH204_RS15735	COG1017	nitric oxide dioxygenase activity
EH204_RS15745	COG4677	pectinesterase activity
EH204_RS15750	COG0347	Belongs to the P(II) protein family
EH204_RS15755	COG2204	response regulator
EH204_RS15760	COG3170	Tfp pilus assembly protein FimV
EH204_RS15765	COG2205	protein histidine kinase activity
EH204_RS15770	COG0047	phosphoribosylformylglycinamidine synthase activity
EH204_RS15770	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EH204_RS15775	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EH204_RS15780	COG0590	tRNA wobble adenosine to inosine editing
EH204_RS15785	COG0560	Phosphoserine phosphatase
EH204_RS15790	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EH204_RS15800	COG3287	FIST C domain
EH204_RS15800	COG2199	diguanylate cyclase activity
EH204_RS15800	COG2200	EAL domain
EH204_RS15835	COG2200	EAL domain
EH204_RS15840	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH204_RS15845	COG0736	holo-[acyl-carrier-protein] synthase activity
EH204_RS15850	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EH204_RS15855	COG1381	Involved in DNA repair and RecF pathway recombination
EH204_RS15860	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EH204_RS15865	COG0571	ribonuclease III activity
EH204_RS15870	COG0681	Belongs to the peptidase S26 family
EH204_RS15875	COG0481	GTPase activity
EH204_RS15885	COG3086	response to oxidative stress
EH204_RS15905	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EH204_RS15910	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EH204_RS15915	COG0513	Belongs to the DEAD box helicase family
EH204_RS15920	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
EH204_RS15925	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EH204_RS15940	COG2819	hydrolase of the alpha beta superfamily
EH204_RS15945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH204_RS15975	COG1902	pentaerythritol trinitrate reductase activity
EH204_RS15980	COG0667	Aldo Keto reductase
EH204_RS15995	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EH204_RS16000	COG4208	sulfate ABC transporter
EH204_RS16010	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EH204_RS16015	COG3835	regulator
EH204_RS16025	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EH204_RS16030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EH204_RS16035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH204_RS16045	COG0316	Belongs to the HesB IscA family
EH204_RS16050	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EH204_RS16055	COG0625	glutathione transferase activity
EH204_RS16060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH204_RS16070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH204_RS16075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH204_RS16080	COG1120	ATPase activity
EH204_RS16085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EH204_RS16090	COG1643	Atp-dependent helicase
EH204_RS16095	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EH204_RS16100	COG1489	DNA binding
EH204_RS16105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EH204_RS16110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH204_RS16120	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EH204_RS16125	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EH204_RS16130	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EH204_RS16135	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EH204_RS16140	COG0842	Transport permease protein
EH204_RS16145	COG1131	(ABC) transporter
EH204_RS16150	COG0288	reversible hydration of carbon dioxide
EH204_RS16165	COG3842	ATPase activity
EH204_RS16180	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EH204_RS16185	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EH204_RS16190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EH204_RS16195	COG1780	Probably involved in ribonucleotide reductase function
EH204_RS16205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EH204_RS16215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EH204_RS16220	COG0328	RNA-DNA hybrid ribonuclease activity
EH204_RS16225	COG2226	methyltransferase
EH204_RS16230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EH204_RS16235	COG1388	LysM domain
EH204_RS16235	COG0741	lytic transglycosylase activity
EH204_RS16240	COG3021	interspecies interaction between organisms
EH204_RS16270	COG0542	response to heat
EH204_RS16280	COG0564	pseudouridine synthase activity
EH204_RS16285	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH204_RS16290	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EH204_RS16295	COG1605	Chorismate mutase
EH204_RS16295	COG0077	Prephenate dehydratase
EH204_RS16300	COG1605	Chorismate mutase
EH204_RS16300	COG0287	Prephenate dehydrogenase
EH204_RS16305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EH204_RS16310	COG3279	Response regulator of the LytR AlgR family
EH204_RS16320	COG2264	protein methyltransferase activity
EH204_RS16325	COG0335	large ribosomal subunit rRNA binding
EH204_RS16330	COG0336	Belongs to the RNA methyltransferase TrmD family
EH204_RS16335	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EH204_RS16340	COG0228	four-way junction DNA binding
EH204_RS16345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EH204_RS16350	COG4137	Cytochrome C assembly protein
EH204_RS16355	COG1854	S-ribosylhomocysteine lyase activity
EH204_RS16360	COG2918	glutathione biosynthetic process
EH204_RS16365	COG1238	metal cluster binding
EH204_RS16370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH204_RS16395	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EH204_RS16400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EH204_RS16405	COG2137	regulation of response to DNA damage stimulus
EH204_RS16410	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EH204_RS16415	COG1546	Belongs to the CinA family
EH204_RS16435	COG3706	GGDEF domain
EH204_RS16435	COG0745	RESPONSE REGULATOR receiver
EH204_RS16440	COG2814	Major facilitator Superfamily
EH204_RS16445	COG0583	DNA-binding transcription factor activity
EH204_RS16450	COG2999	glutathione oxidoreductase activity
EH204_RS16465	COG3209	COG3209 Rhs family protein
EH204_RS16535	COG3501	Rhs element vgr protein
EH204_RS16570	COG2204	response regulator
EH204_RS16670	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EH204_RS16675	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EH204_RS16695	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EH204_RS16700	COG2195	Cleaves the N-terminal amino acid of tripeptides
EH204_RS16705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EH204_RS16715	COG2226	methyltransferase
EH204_RS16720	COG3034	peptidoglycan biosynthetic process
EH204_RS16725	COG0121	glutamine amidotransferase
EH204_RS16730	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EH204_RS16735	COG1960	acyl-CoA dehydrogenase activity
EH204_RS16740	COG1403	HNH endonuclease
EH204_RS16745	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EH204_RS16750	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EH204_RS16785	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EH204_RS16790	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
EH204_RS16795	COG0235	Class ii aldolase
EH204_RS16800	COG0436	Aminotransferase
EH204_RS16820	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EH204_RS16875	COG4175	Glycine betaine
EH204_RS16880	COG4176	ABC-type proline glycine betaine transport system permease component
EH204_RS16885	COG2113	Glycine betaine
EH204_RS16890	COG2706	6-phosphogluconolactonase activity
EH204_RS16895	COG2814	Major facilitator Superfamily
EH204_RS16900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EH204_RS16910	COG1846	Transcriptional regulator
EH204_RS16915	COG1566	PFAM secretion protein HlyD family protein
EH204_RS16920	COG2814	Major facilitator Superfamily
EH204_RS16925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EH204_RS16935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH204_RS16940	COG3118	belongs to the thioredoxin family
EH204_RS16950	COG1042	CoA-binding domain protein
EH204_RS16950	COG0045	succinate-CoA ligase (ADP-forming) activity
EH204_RS16950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH204_RS16955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH204_RS16960	COG0477	Major facilitator Superfamily
EH204_RS17000	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EH204_RS17005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EH204_RS17010	COG2011	ABC-type metal ion transport system permease component
EH204_RS17015	COG1464	Belongs to the NlpA lipoprotein family
EH204_RS17025	COG1720	tRNA m6t6A37 methyltransferase activity
EH204_RS17030	COG0442	prolyl-tRNA aminoacylation
EH204_RS17035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH204_RS17040	COG4942	peptidase
EH204_RS17040	COG1388	LysM domain
EH204_RS17045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EH204_RS17050	COG0585	pseudouridine synthase activity
EH204_RS17055	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EH204_RS17060	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EH204_RS17065	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EH204_RS17075	COG0765	amino acid transport
EH204_RS17080	COG1126	abc transporter atp-binding protein
EH204_RS17090	COG0529	Catalyzes the synthesis of activated sulfate
EH204_RS17095	COG2895	sulfate adenylyltransferase (ATP) activity
EH204_RS17100	COG0175	sulfate reduction
EH204_RS17105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EH204_RS17105	COG1648	precorrin-2 dehydrogenase activity
EH204_RS17110	COG0175	sulfate reduction
EH204_RS17115	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EH204_RS17120	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EH204_RS17130	COG2200	EAL domain
EH204_RS17150	COG0720	synthase
EH204_RS17155	COG0602	queuosine metabolic process
EH204_RS17160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EH204_RS17175	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS17180	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EH204_RS17190	COG0583	DNA-binding transcription factor activity
EH204_RS17225	COG0148	phosphopyruvate hydratase activity
EH204_RS17230	COG0504	CTP synthase activity
EH204_RS17235	COG3956	TIGRFAM MazG family protein
EH204_RS17240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EH204_RS17255	COG1929	Belongs to the glycerate kinase type-1 family
EH204_RS17260	COG2084	Dehydrogenase
EH204_RS17270	COG4948	Mandelate Racemase Muconate Lactonizing
EH204_RS17275	COG4948	Mandelate Racemase Muconate Lactonizing
EH204_RS17280	COG2271	Major facilitator Superfamily
EH204_RS17290	COG0840	transmembrane signaling receptor activity
EH204_RS17305	COG3530	Putative quorum-sensing-regulated virulence factor
EH204_RS17310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EH204_RS17315	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EH204_RS17315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EH204_RS17320	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EH204_RS17325	COG3025	triphosphatase activity
EH204_RS17330	COG4991	sh3 domain protein
EH204_RS17335	COG0617	tRNA 3'-terminal CCA addition
EH204_RS17340	COG1968	undecaprenyl-diphosphatase activity
EH204_RS17345	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EH204_RS17350	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EH204_RS17355	COG0840	transmembrane signaling receptor activity
EH204_RS17360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EH204_RS17365	COG2105	PFAM AIG2 family protein
EH204_RS17370	COG2911	Protein conserved in bacteria
EH204_RS17375	COG0729	surface antigen
EH204_RS17380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EH204_RS17385	COG1253	flavin adenine dinucleotide binding
EH204_RS17395	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EH204_RS17400	COG1218	3'(2'),5'-bisphosphate nucleotidase
EH204_RS17405	COG0737	Belongs to the 5'-nucleotidase family
EH204_RS17410	COG1733	regulation of RNA biosynthetic process
EH204_RS17425	COG3961	Belongs to the TPP enzyme family
EH204_RS17430	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EH204_RS17435	COG0545	Peptidyl-prolyl cis-trans isomerase
EH204_RS17440	COG3061	Opacity-associated protein A
EH204_RS17450	COG0359	binds to the 23S rRNA
EH204_RS17455	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EH204_RS17460	COG2965	DNA replication, synthesis of RNA primer
EH204_RS17465	COG0360	Binds together with S18 to 16S ribosomal RNA
EH204_RS17470	COG1073	alpha beta
EH204_RS17475	COG0840	transmembrane signaling receptor activity
EH204_RS17480	COG1690	Belongs to the RtcB family
EH204_RS17485	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EH204_RS17495	COG3766	membrane
EH204_RS17505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH204_RS17510	COG0557	exoribonuclease II activity
EH204_RS17515	COG1959	2 iron, 2 sulfur cluster binding
EH204_RS17520	COG0840	transmembrane signaling receptor activity
EH204_RS17525	COG3706	GGDEF domain
EH204_RS17530	COG2805	Type II/IV secretion system protein
EH204_RS17535	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EH204_RS17540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EH204_RS17545	COG0762	integral membrane protein
EH204_RS17550	COG1872	DUF167
EH204_RS17555	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EH204_RS17560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EH204_RS17565	COG0840	transmembrane signaling receptor activity
EH204_RS17575	COG2153	protein acetylation
EH204_RS17580	COG0477	Major facilitator Superfamily
EH204_RS17595	COG2186	Transcriptional regulator
EH204_RS17600	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH204_RS17605	COG2723	6-phospho-beta-galactosidase activity
EH204_RS17610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH204_RS17615	COG1447	Phosphotransferase system cellobiose-specific component IIA
EH204_RS17635	COG0019	diaminopimelate decarboxylase activity
EH204_RS17640	COG0583	DNA-binding transcription factor activity
EH204_RS17660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EH204_RS17670	COG2124	cytochrome p450
EH204_RS17680	COG0305	Participates in initiation and elongation during chromosome replication
EH204_RS17685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EH204_RS17695	COG1522	sequence-specific DNA binding
EH204_RS17705	COG1448	Aminotransferase
EH204_RS17710	COG1451	nucleotide metabolic process
EH204_RS17750	COG1518	maintenance of DNA repeat elements
EH204_RS17755	COG1203	CRISPR-associated helicase, Cas3
EH204_RS17780	COG0432	Pfam Uncharacterised protein family UPF0047
EH204_RS17785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EH204_RS17790	COG0629	single-stranded DNA binding
EH204_RS17810	COG0395	ABC-type sugar transport system, permease component
EH204_RS17815	COG1175	transmembrane transport
EH204_RS17825	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EH204_RS17845	COG2971	BadF BadG BcrA BcrD
EH204_RS17855	COG1121	(ABC) transporter
EH204_RS17860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH204_RS17865	COG0803	Belongs to the bacterial solute-binding protein 9 family
EH204_RS17875	COG1349	DNA-binding transcription factor activity
EH204_RS17880	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EH204_RS17885	COG3395	kinase activity
EH204_RS17890	COG1454	alcohol dehydrogenase
EH204_RS17895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EH204_RS17910	COG2731	YhcH YjgK YiaL family protein
EH204_RS17915	COG1028	Short-chain dehydrogenase reductase Sdr
EH204_RS17920	COG1882	Formate acetyltransferase
EH204_RS17925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EH204_RS17950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH204_RS17965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EH204_RS17970	COG3112	Uncharacterised protein family (UPF0231)
EH204_RS17990	COG0640	Transcriptional regulator
EH204_RS18000	COG2207	Transcriptional regulator
EH204_RS18005	COG2079	MmgE PrpD family protein
EH204_RS18015	COG1073	alpha beta
EH204_RS18020	COG2814	Major facilitator Superfamily
EH204_RS18030	COG0583	DNA-binding transcription factor activity
EH204_RS18035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH204_RS18040	COG0508	dehydrogenase complex catalyzes the overall conversion of
EH204_RS18045	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EH204_RS18050	COG2186	Transcriptional regulator
EH204_RS18060	COG1113	amino acid transport
EH204_RS18065	COG2211	Major facilitator Superfamily
EH204_RS18070	COG3940	Belongs to the glycosyl hydrolase 43 family
EH204_RS18075	COG3725	Membrane protein required for beta-lactamase induction
EH204_RS18080	COG3023	N-Acetylmuramoyl-L-alanine amidase
EH204_RS18085	COG3248	Nucleoside-binding outer membrane protein
EH204_RS18095	COG4969	Belongs to the N-Me-Phe pilin family
EH204_RS18100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EH204_RS18105	COG1459	type II secretion system
EH204_RS18110	COG0516	GMP reductase activity
EH204_RS18115	COG0237	dephospho-CoA kinase activity
EH204_RS18120	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EH204_RS18125	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EH204_RS18130	COG0494	nUDIX hydrolase
EH204_RS18135	COG0653	protein targeting
EH204_RS18150	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EH204_RS18155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EH204_RS18160	COG0849	cell division
EH204_RS18165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EH204_RS18170	COG1181	Belongs to the D-alanine--D-alanine ligase family
EH204_RS18175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EH204_RS18180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EH204_RS18185	COG0772	Belongs to the SEDS family
EH204_RS18190	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EH204_RS18195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH204_RS18200	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EH204_RS18205	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EH204_RS18210	COG0768	penicillin binding
EH204_RS18215	COG3116	cell division
EH204_RS18220	COG0275	rRNA processing
EH204_RS18225	COG2001	Belongs to the MraZ family
EH204_RS18235	COG1609	Transcriptional regulator
EH204_RS18245	COG0028	Belongs to the TPP enzyme family
EH204_RS18250	COG1022	Amp-dependent synthetase and ligase
EH204_RS18255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EH204_RS18260	COG0473	3-isopropylmalate dehydrogenase activity
EH204_RS18265	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EH204_RS18270	COG0066	3-isopropylmalate dehydratase activity
EH204_RS18290	COG0840	transmembrane signaling receptor activity
EH204_RS18310	COG4533	DNA binding
EH204_RS18315	COG4143	(ABC) transporter
EH204_RS18320	COG1178	ABC-type Fe3 transport system permease component
EH204_RS18325	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EH204_RS18330	COG3507	Belongs to the glycosyl hydrolase 43 family
EH204_RS18335	COG0028	Belongs to the TPP enzyme family
EH204_RS18340	COG0440	acetolactate synthase activity
EH204_RS18345	COG0586	Pfam SNARE associated Golgi protein
EH204_RS18350	COG3706	GGDEF domain
EH204_RS18355	COG0417	DNA replication proofreading
EH204_RS18360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH204_RS18365	COG0564	pseudouridine synthase activity
EH204_RS18370	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EH204_RS18375	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EH204_RS18380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH204_RS18385	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EH204_RS18390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EH204_RS18395	COG2967	ApaG domain
EH204_RS18400	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EH204_RS18420	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EH204_RS18425	COG3610	response to peptide
EH204_RS18430	COG2966	Psort location CytoplasmicMembrane, score
EH204_RS18450	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EH204_RS18455	COG0505	Belongs to the CarA family
EH204_RS18460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EH204_RS18465	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EH204_RS18470	COG1047	Peptidyl-prolyl cis-trans
EH204_RS18475	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EH204_RS18480	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EH204_RS18485	COG0196	riboflavin kinase activity
EH204_RS18490	COG0268	Binds directly to 16S ribosomal RNA
EH204_RS18495	COG0583	DNA-binding transcription factor activity
EH204_RS18500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EH204_RS18505	COG0484	heat shock protein binding
EH204_RS18510	COG0443	Heat shock 70 kDa protein
EH204_RS18515	COG1584	GPR1 FUN34 yaaH family protein
EH204_RS18530	COG3706	GGDEF domain
EH204_RS18530	COG0745	RESPONSE REGULATOR receiver
EH204_RS18535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EH204_RS18540	COG3022	response to hydroperoxide
EH204_RS18550	COG0083	homoserine kinase activity
EH204_RS18565	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EH204_RS18570	COG0745	RESPONSE REGULATOR receiver
EH204_RS18575	COG3045	CreA protein
EH204_RS18580	COG3708	Transcriptional regulator
EH204_RS18580	COG2207	Transcriptional regulator
EH204_RS18590	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EH204_RS18595	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EH204_RS18605	COG0488	(ABC) transporter
EH204_RS18610	COG0840	transmembrane signaling receptor activity
EH204_RS18615	COG0583	DNA-binding transcription factor activity
EH204_RS18620	COG0604	alcohol dehydrogenase
EH204_RS18625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH204_RS18630	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EH204_RS18635	COG0583	DNA-binding transcription factor activity
EH204_RS18645	COG1279	arginine transmembrane transporter activity
EH204_RS18650	COG0668	transmembrane transport
EH204_RS18655	COG0191	fructose-bisphosphate aldolase activity
EH204_RS18660	COG0126	phosphoglycerate kinase activity
EH204_RS18665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EH204_RS18670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EH204_RS18675	COG0501	Belongs to the peptidase M48B family
EH204_RS18685	COG1166	arginine decarboxylase activity
EH204_RS18690	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EH204_RS18695	COG3091	SprT-like family
EH204_RS18700	COG2356	endonuclease I
EH204_RS18705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EH204_RS18710	COG0189	ligase activity
EH204_RS18715	COG1678	Uncharacterized ACR, COG1678
EH204_RS18720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EH204_RS18725	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EH204_RS18730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EH204_RS18735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EH204_RS18740	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EH204_RS18745	COG0330	HflC and HflK could
EH204_RS18750	COG0330	HflC and HflK could
EH204_RS18755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EH204_RS18760	COG1923	regulation of RNA biosynthetic process
EH204_RS18765	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EH204_RS18770	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EH204_RS18775	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH204_RS18780	COG0802	atpase or kinase
EH204_RS18785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EH204_RS18785	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EH204_RS18790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EH204_RS18800	COG0450	alkyl hydroperoxide reductase
EH204_RS18805	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EH204_RS18830	COG1136	(ABC) transporter
EH204_RS18830	COG0577	efflux transmembrane transporter activity
EH204_RS18835	COG1136	(ABC) transporter
EH204_RS18850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH204_RS18860	COG1064	alcohol dehydrogenase
EH204_RS18880	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EH204_RS18885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH204_RS18905	COG2814	Major facilitator Superfamily
EH204_RS18930	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EH204_RS18935	COG1162	GTPase activity
EH204_RS18940	COG0688	phosphatidylethanolamine metabolic process
EH204_RS18945	COG1511	domain protein
EH204_RS18945	COG3264	Mechanosensitive ion channel
EH204_RS18950	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EH204_RS18955	COG1053	succinate dehydrogenase
EH204_RS18960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EH204_RS18965	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EH204_RS18970	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EH204_RS18975	COG3040	lipid binding
EH204_RS18990	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EH204_RS18995	COG1509	lysine 2,3-aminomutase activity
EH204_RS19005	COG0166	Belongs to the GPI family
EH204_RS19010	COG0527	aspartate kinase activity
EH204_RS19020	COG0471	metal ion transport
EH204_RS19030	COG2207	Transcriptional regulator
EH204_RS19035	COG1410	methionine synthase
EH204_RS19035	COG0646	methionine synthase
EH204_RS19045	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EH204_RS19055	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EH204_RS19060	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EH204_RS19085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EH204_RS19095	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EH204_RS19100	COG0009	L-threonylcarbamoyladenylate synthase
EH204_RS19105	COG0551	DNA topoisomerase type I activity
EH204_RS19110	COG2922	Belongs to the Smg family
EH204_RS19115	COG0758	DNA mediated transformation
EH204_RS19120	COG0242	peptide deformylase activity
EH204_RS19125	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EH204_RS19130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EH204_RS19130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EH204_RS19135	COG0569	domain protein
EH204_RS19140	COG1970	mechanosensitive ion channel activity
EH204_RS19145	COG3036	rescue of stalled ribosome
EH204_RS19150	COG0203	ribosomal protein L17
EH204_RS19155	COG0202	RNA polymerase activity
EH204_RS19160	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EH204_RS19170	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EH204_RS19175	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EH204_RS19180	COG0201	protein transport
EH204_RS19185	COG0200	Binds to the 23S rRNA
EH204_RS19190	COG1841	ribosomal large subunit assembly
EH204_RS19195	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EH204_RS19200	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EH204_RS19205	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EH204_RS19210	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EH204_RS19215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EH204_RS19220	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EH204_RS19225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EH204_RS19230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EH204_RS19235	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EH204_RS19240	COG0255	Belongs to the universal ribosomal protein uL29 family
EH204_RS19245	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EH204_RS19250	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EH204_RS19255	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EH204_RS19260	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EH204_RS19265	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EH204_RS19275	COG0088	Forms part of the polypeptide exit tunnel
EH204_RS19280	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EH204_RS19285	COG0051	transcription antitermination factor activity, RNA binding
EH204_RS19305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EH204_RS19310	COG0049	tRNA binding
EH204_RS19315	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EH204_RS19320	COG2168	tRNA wobble position uridine thiolation
EH204_RS19325	COG2923	Belongs to the DsrF TusC family
EH204_RS19330	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EH204_RS19335	COG2964	Protein conserved in bacteria
EH204_RS19345	COG0745	RESPONSE REGULATOR receiver
EH204_RS19350	COG0642	Histidine kinase
EH204_RS19355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EH204_RS19370	COG0545	Peptidyl-prolyl cis-trans isomerase
EH204_RS19375	COG2900	Belongs to the SlyX family
EH204_RS19380	COG1047	Peptidyl-prolyl cis-trans
EH204_RS19385	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EH204_RS19390	COG0475	glutathione-regulated potassium exporter activity
EH204_RS19390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EH204_RS19395	COG2249	NAD(P)H dehydrogenase (quinone) activity
EH204_RS19400	COG0488	(ABC) transporter
EH204_RS19410	COG0429	hydrolase of the alpha beta-hydrolase fold
EH204_RS19415	COG3089	Belongs to the UPF0270 family
EH204_RS19420	COG3954	Phosphoribulokinase
EH204_RS19425	COG1765	OsmC-like protein
EH204_RS19430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH204_RS19465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EH204_RS19470	COG4608	Belongs to the ABC transporter superfamily
EH204_RS19475	COG0444	Belongs to the ABC transporter superfamily
EH204_RS19485	COG0601	transmembrane transport
EH204_RS19490	COG0747	negative chemotaxis
EH204_RS19495	COG4948	Mandelate Racemase Muconate Lactonizing
EH204_RS19505	COG2146	nitrite reductase [NAD(P)H] activity
EH204_RS19535	COG1473	amidohydrolase
EH204_RS19545	COG0546	phosphoglycolate phosphatase activity
EH204_RS19550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EH204_RS19565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EH204_RS19570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EH204_RS19575	COG4796	Type ii and iii secretion system protein
EH204_RS19600	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EH204_RS19610	COG0494	nUDIX hydrolase
EH204_RS19620	COG1011	Hydrolase
EH204_RS19625	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EH204_RS19630	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EH204_RS19635	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EH204_RS19645	COG0745	RESPONSE REGULATOR receiver
EH204_RS19665	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EH204_RS19670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH204_RS19675	COG0019	diaminopimelate decarboxylase activity
EH204_RS19680	COG4774	siderophore transport
EH204_RS19685	COG4264	IucA IucC family
EH204_RS19695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EH204_RS19715	COG0840	transmembrane signaling receptor activity
EH204_RS19725	COG2183	response to ionizing radiation
EH204_RS19730	COG1414	Transcriptional regulator
EH204_RS19760	COG1785	Belongs to the alkaline phosphatase family
EH204_RS19770	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EH204_RS19775	COG1335	isochorismatase
EH204_RS19780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH204_RS19785	COG2267	carboxylic ester hydrolase activity
EH204_RS19790	COG1040	competence protein
EH204_RS19795	COG0316	Belongs to the HesB IscA family
EH204_RS19795	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EH204_RS19800	COG1640	4-alpha-glucanotransferase
EH204_RS19805	COG0058	SHG alpha-glucan phosphorylase activity
EH204_RS19810	COG1349	DNA-binding transcription factor activity
EH204_RS19815	COG0705	Rhomboid family
EH204_RS19825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH204_RS19830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EH204_RS19835	COG3501	Rhs element vgr protein
EH204_RS19855	COG0058	SHG alpha-glucan phosphorylase activity
EH204_RS19860	COG0297	glycogen (starch) synthase activity
EH204_RS19865	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EH204_RS19870	COG1523	belongs to the glycosyl hydrolase 13 family
EH204_RS19875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EH204_RS19880	COG3275	phosphorelay sensor kinase activity
EH204_RS19890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EH204_RS19895	COG2095	MarC family integral membrane protein
EH204_RS19900	COG2610	gluconate transmembrane transporter activity
EH204_RS19905	COG3265	gluconokinase activity
EH204_RS19910	COG1609	Transcriptional regulator
EH204_RS19915	COG1741	Belongs to the pirin family
EH204_RS19920	COG0247	lactate metabolic process
EH204_RS19925	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EH204_RS19930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EH204_RS19935	COG2271	Major facilitator Superfamily
EH204_RS19940	COG0584	glycerophosphoryl diester phosphodiesterase
EH204_RS19945	COG0561	phosphatase activity
EH204_RS19950	COG2267	carboxylic ester hydrolase activity
EH204_RS19955	COG1280	lysine exporter protein (LysE YggA)
EH204_RS19960	COG1280	lysine exporter protein (LysE YggA)
EH204_RS19965	COG0514	ATP-dependent DNA helicase (RecQ)
EH204_RS19970	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EH204_RS19975	COG2050	protein possibly involved in aromatic compounds catabolism
EH204_RS19985	COG3180	Ammonia monooxygenase
EH204_RS19990	COG0598	Magnesium transport protein CorA
EH204_RS19995	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EH204_RS20000	COG0210	DNA helicase
EH204_RS20005	COG1011	Hydrolase
EH204_RS20020	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EH204_RS20030	COG1965	Belongs to the frataxin family
EH204_RS20035	COG2814	Major facilitator Superfamily
EH204_RS20045	COG0181	hydroxymethylbilane synthase activity
EH204_RS20055	COG2959	enzyme of heme biosynthesis
EH204_RS20060	COG3071	HemY protein
EH204_RS20065	COG1802	Transcriptional regulator
EH204_RS20085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH204_RS20090	COG4597	amino acid ABC transporter
EH204_RS20095	COG0765	amino acid transport
EH204_RS20100	COG1126	abc transporter atp-binding protein
EH204_RS20110	COG1126	abc transporter atp-binding protein
EH204_RS20115	COG0765	amino acid transport
EH204_RS20120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH204_RS20130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EH204_RS20160	COG1113	amino acid transport
EH204_RS20165	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EH204_RS20175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EH204_RS20180	COG2244	polysaccharide biosynthetic process
EH204_RS20185	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EH204_RS20190	COG0456	acetyltransferase
EH204_RS20195	COG1088	dTDP-glucose 4,6-dehydratase activity
EH204_RS20200	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EH204_RS20205	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EH204_RS20210	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EH204_RS20215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH204_RS20220	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EH204_RS20225	COG3118	belongs to the thioredoxin family
EH204_RS20230	COG0513	Belongs to the DEAD box helicase family
EH204_RS20235	COG0248	Ppx GppA phosphatase
EH204_RS20245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH204_RS20250	COG0506	proline dehydrogenase activity
EH204_RS20250	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EH204_RS20250	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EH204_RS20265	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EH204_RS20270	COG0583	DNA-binding transcription factor activity
EH204_RS20290	COG0129	dihydroxy-acid dehydratase activity
EH204_RS20295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EH204_RS20300	COG3978	acetolactate synthase activity
EH204_RS20320	COG3085	chromosome segregation
EH204_RS20325	COG0583	DNA-binding transcription factor activity
EH204_RS20330	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH204_RS20335	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH204_RS20340	COG1129	ABC transporter
EH204_RS20345	COG1879	ABC-type sugar transport system periplasmic component
EH204_RS20395	COG1739	Uncharacterized protein family UPF0029
EH204_RS20400	COG0006	proline dipeptidase activity
EH204_RS20405	COG1024	Enoyl-CoA hydratase
EH204_RS20405	COG1250	3-hydroxyacyl-CoA dehydrogenase
EH204_RS20410	COG0183	Belongs to the thiolase family
EH204_RS20420	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EH204_RS20425	COG0250	Participates in transcription elongation, termination and antitermination
EH204_RS20435	COG0084	hydrolase, TatD family'
EH204_RS20440	COG0805	protein transport
EH204_RS20445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EH204_RS20450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EH204_RS20455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EH204_RS20470	COG1322	Protein conserved in bacteria
EH204_RS20475	COG0165	Argininosuccinate lyase
EH204_RS20480	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EH204_RS20485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EH204_RS20490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EH204_RS20500	COG4948	Mandelate Racemase Muconate Lactonizing
EH204_RS20505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH204_RS20505	COG1263	PTS System
EH204_RS20505	COG2190	(PTS) system
EH204_RS20510	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EH204_RS20520	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EH204_RS20525	COG0412	Dienelactone hydrolase
EH204_RS20530	COG0840	transmembrane signaling receptor activity
EH204_RS20535	COG0840	transmembrane signaling receptor activity
EH204_RS20540	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EH204_RS20545	COG0583	DNA-binding transcription factor activity
EH204_RS20560	COG1045	serine acetyltransferase
EH204_RS20565	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EH204_RS20570	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EH204_RS20575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH204_RS20580	COG4942	peptidase
EH204_RS20585	COG2861	carbohydrate metabolic process
EH204_RS20590	COG1063	alcohol dehydrogenase
EH204_RS20595	COG0156	8-amino-7-oxononanoate synthase activity
EH204_RS20600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH204_RS20610	COG0859	PFAM glycosyl transferase family 9
EH204_RS20615	COG0859	PFAM glycosyl transferase family 9
EH204_RS20630	COG1519	Transferase
EH204_RS20635	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EH204_RS20640	COG0859	PFAM glycosyl transferase family 9
EH204_RS20645	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EH204_RS20650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EH204_RS20655	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EH204_RS20660	COG2003	Belongs to the UPF0758 family
EH204_RS20665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EH204_RS20670	COG0756	dUTP diphosphatase activity
EH204_RS20675	COG1309	transcriptional regulator
EH204_RS20680	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EH204_RS20685	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EH204_RS20690	COG4948	Mandelate Racemase Muconate Lactonizing
EH204_RS20695	COG4172	Belongs to the ABC transporter superfamily
EH204_RS20700	COG0747	negative chemotaxis
EH204_RS20705	COG0601	transmembrane transport
EH204_RS20710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH204_RS20725	COG1446	asparaginase
EH204_RS20730	COG0583	DNA-binding transcription factor activity
EH204_RS20735	COG1561	YicC-like family, N-terminal region
EH204_RS20775	COG2226	methyltransferase
EH204_RS20800	COG0628	permease
EH204_RS20805	COG1304	FMN binding
EH204_RS20810	COG1012	belongs to the aldehyde dehydrogenase family
EH204_RS20820	COG3239	Fatty acid desaturase
EH204_RS20850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH204_RS20855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EH204_RS20860	COG3136	membrane protein required for alginate biosynthesis
EH204_RS20875	COG4677	pectinesterase activity
EH204_RS20880	COG2771	luxR family
EH204_RS20890	COG0137	argininosuccinate synthase activity
EH204_RS20900	COG2207	Transcriptional regulator
EH204_RS20900	COG1609	Transcriptional regulator
EH204_RS20910	COG1129	ABC transporter
EH204_RS20915	COG4213	ABC transporter substrate-binding protein
EH204_RS20920	COG2115	Belongs to the xylose isomerase family
EH204_RS20925	COG1070	Carbohydrate kinase
EH204_RS20930	COG3274	enterobacterial common antigen metabolic process
EH204_RS20935	COG1012	belongs to the aldehyde dehydrogenase family
EH204_RS20940	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EH204_RS20945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EH204_RS20950	COG0840	transmembrane signaling receptor activity
EH204_RS20960	COG3722	fumarate hydratase activity
EH204_RS20965	COG0246	Mannitol dehydrogenase
EH204_RS20970	COG2213	PTS system mannitol-specific
EH204_RS20970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH204_RS20980	COG0751	glycine-tRNA ligase activity
EH204_RS20985	COG0752	glycyl-tRNA synthetase alpha subunit
EH204_RS20990	COG0730	response to heat
EH204_RS20995	COG2818	Glycosylase
EH204_RS21000	COG0456	acetyltransferase
EH204_RS21005	COG0840	transmembrane signaling receptor activity
EH204_RS21010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH204_RS21030	COG4172	Belongs to the ABC transporter superfamily
EH204_RS21035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH204_RS21050	COG1280	lysine exporter protein (LysE YggA)
EH204_RS21055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EH204_RS21075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH204_RS21080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EH204_RS21100	COG2214	Heat shock protein DnaJ domain protein
EH204_RS21105	COG0443	Heat shock 70 kDa protein
EH204_RS21120	COG3712	iron ion homeostasis
EH204_RS21125	COG1595	DNA-templated transcription, initiation
EH204_RS21130	COG1629	transport
EH204_RS21140	COG0742	ribosomal rna small subunit methyltransferase
EH204_RS21170	COG2214	Heat shock protein DnaJ domain protein
EH204_RS21175	COG0443	Heat shock 70 kDa protein
EH204_RS21190	COG3712	iron ion homeostasis
EH204_RS21195	COG1595	DNA-templated transcription, initiation
EH204_RS21200	COG1629	transport
EH204_RS21210	COG0742	ribosomal rna small subunit methyltransferase
EH204_RS21215	COG0737	Belongs to the 5'-nucleotidase family
EH204_RS21225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EH204_RS21230	COG0589	response to stress
EH204_RS21240	COG0306	phosphate transporter
EH204_RS21245	COG2081	HI0933 family
EH204_RS21250	COG2207	Transcriptional regulator
EH204_RS21255	COG2200	EAL domain
EH204_RS21270	COG2194	sulfuric ester hydrolase activity
EH204_RS21275	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EH204_RS21280	COG0194	GDP metabolic process
EH204_RS21285	COG1758	RNA polymerase activity
EH204_RS21290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EH204_RS21295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH204_RS21300	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EH204_RS21305	COG2233	PERMEase
EH204_RS21310	COG2982	Protein involved in outer membrane biogenesis
EH204_RS21315	COG0456	acetyltransferase
EH204_RS21320	COG1490	D-aminoacyl-tRNA deacylase activity
EH204_RS21325	COG1011	Hydrolase
EH204_RS21335	COG0174	glutamine synthetase
EH204_RS21340	COG3852	Histidine kinase
EH204_RS21360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EH204_RS21365	COG3078	GTPase activator activity
EH204_RS21375	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EH204_RS21380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH204_RS21380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH204_RS21390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EH204_RS21395	COG3084	Protein conserved in bacteria
EH204_RS21405	COG1763	Mo-molybdopterin cofactor biosynthetic process
EH204_RS21430	COG1609	Transcriptional regulator
EH204_RS21435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH204_RS21440	COG1879	ABC-type sugar transport system periplasmic component
EH204_RS21445	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH204_RS21450	COG1129	ABC transporter
EH204_RS21455	COG1869	D-ribose catabolic process
EH204_RS21460	COG3111	PFAM Bacterial OB fold (BOF) protein
EH204_RS21465	COG0745	RESPONSE REGULATOR receiver
EH204_RS21470	COG0642	Histidine kinase
EH204_RS21475	COG3158	transport of potassium into the cell
EH204_RS21480	COG0714	Associated with various cellular activities
EH204_RS21485	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EH204_RS21490	COG2502	aspartate--ammonia ligase
EH204_RS21495	COG1522	sequence-specific DNA binding
EH204_RS21500	COG0716	FMN binding
EH204_RS21505	COG0445	tRNA wobble uridine modification
EH204_RS21510	COG0357	Ribosomal RNA small subunit methyltransferase G
EH204_RS21515	COG3312	ion transport
EH204_RS21520	COG0356	it plays a direct role in the translocation of protons across the membrane
EH204_RS21530	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EH204_RS21535	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EH204_RS21540	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EH204_RS21545	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EH204_RS21550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EH204_RS21555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EH204_RS21565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EH204_RS21570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EH204_RS21580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EH204_RS21585	COG0573	inorganic phosphate transmembrane transporter activity
EH204_RS21590	COG0581	inorganic phosphate transmembrane transporter activity
EH204_RS21595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EH204_RS21605	COG1396	sequence-specific DNA binding
EH204_RS21610	COG3135	benzoate transporter
EH204_RS21615	COG0346	lactoylglutathione lyase activity
EH204_RS21625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH204_RS21630	COG0765	amino acid transport
EH204_RS21635	COG0765	amino acid transport
EH204_RS21640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH204_RS21645	COG2252	PERMEase
EH204_RS21650	COG2091	lysine biosynthetic process via aminoadipic acid
EH204_RS21655	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH204_RS21660	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH204_RS21660	COG0493	'glutamate synthase
EH204_RS21690	COG1733	regulation of RNA biosynthetic process
EH204_RS21695	COG0702	epimerase
EH204_RS21705	COG1396	sequence-specific DNA binding
EH204_RS21710	COG3550	peptidyl-serine autophosphorylation
EH204_RS21715	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EH204_RS21720	COG0706	membrane insertase activity
EH204_RS21730	COG0594	ribonuclease P activity
EH204_RS21735	COG0230	Belongs to the bacterial ribosomal protein bL34 family