locus-tag	class	description
BCS7_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BCS7_RS00010	COG0592	DNA-directed DNA polymerase activity
BCS7_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCS7_RS00035	COG0840	transmembrane signaling receptor activity
BCS7_RS00040	COG1609	Transcriptional regulator
BCS7_RS00045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCS7_RS00050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCS7_RS00055	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCS7_RS00060	COG2723	6-phospho-beta-galactosidase activity
BCS7_RS00070	COG0737	Belongs to the 5'-nucleotidase family
BCS7_RS00075	COG0742	ribosomal rna small subunit methyltransferase
BCS7_RS00080	COG0339	signal peptide processing
BCS7_RS00085	COG1629	transport
BCS7_RS00090	COG1595	DNA-templated transcription, initiation
BCS7_RS00095	COG3712	iron ion homeostasis
BCS7_RS00110	COG0443	Heat shock 70 kDa protein
BCS7_RS00115	COG2214	Heat shock protein DnaJ domain protein
BCS7_RS00125	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BCS7_RS00130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCS7_RS00150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCS7_RS00155	COG1280	lysine exporter protein (LysE YggA)
BCS7_RS00170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCS7_RS00175	COG4172	Belongs to the ABC transporter superfamily
BCS7_RS00180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCS7_RS00195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCS7_RS00210	COG2818	Glycosylase
BCS7_RS00215	COG0730	response to heat
BCS7_RS00220	COG0752	glycyl-tRNA synthetase alpha subunit
BCS7_RS00225	COG0751	glycine-tRNA ligase activity
BCS7_RS00235	COG2213	PTS system mannitol-specific
BCS7_RS00235	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCS7_RS00240	COG0246	Mannitol dehydrogenase
BCS7_RS00245	COG3722	fumarate hydratase activity
BCS7_RS00260	COG0840	transmembrane signaling receptor activity
BCS7_RS00265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCS7_RS00270	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BCS7_RS00275	COG1012	belongs to the aldehyde dehydrogenase family
BCS7_RS00280	COG3274	enterobacterial common antigen metabolic process
BCS7_RS00285	COG1070	Carbohydrate kinase
BCS7_RS00290	COG2115	Belongs to the xylose isomerase family
BCS7_RS00295	COG4213	ABC transporter substrate-binding protein
BCS7_RS00300	COG1129	ABC transporter
BCS7_RS00305	COG4214	carbohydrate transport
BCS7_RS00310	COG2207	Transcriptional regulator
BCS7_RS00310	COG1609	Transcriptional regulator
BCS7_RS00320	COG0137	argininosuccinate synthase activity
BCS7_RS00330	COG2771	luxR family
BCS7_RS00335	COG4677	pectinesterase activity
BCS7_RS00340	COG3136	membrane protein required for alginate biosynthesis
BCS7_RS00350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCS7_RS00380	COG3239	Fatty acid desaturase
BCS7_RS00390	COG1012	belongs to the aldehyde dehydrogenase family
BCS7_RS00395	COG1304	FMN binding
BCS7_RS00400	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCS7_RS00400	COG0456	acetyltransferase
BCS7_RS00405	COG0628	permease
BCS7_RS00440	COG3423	Transcriptional regulator
BCS7_RS00470	COG1561	YicC-like family, N-terminal region
BCS7_RS00475	COG0583	DNA-binding transcription factor activity
BCS7_RS00480	COG1446	asparaginase
BCS7_RS00485	COG2362	D-Aminopeptidase
BCS7_RS00495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCS7_RS00500	COG0601	transmembrane transport
BCS7_RS00505	COG0747	negative chemotaxis
BCS7_RS00510	COG4172	Belongs to the ABC transporter superfamily
BCS7_RS00515	COG4948	Mandelate Racemase Muconate Lactonizing
BCS7_RS00520	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BCS7_RS00525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BCS7_RS00530	COG1309	transcriptional regulator
BCS7_RS00535	COG0756	dUTP diphosphatase activity
BCS7_RS00540	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCS7_RS00545	COG2003	Belongs to the UPF0758 family
BCS7_RS00550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BCS7_RS00565	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCS7_RS00570	COG0859	PFAM glycosyl transferase family 9
BCS7_RS00575	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BCS7_RS00580	COG1519	Transferase
BCS7_RS00595	COG0562	UDP-galactopyranose mutase
BCS7_RS00625	COG0438	transferase activity, transferring glycosyl groups
BCS7_RS00630	COG0859	PFAM glycosyl transferase family 9
BCS7_RS00635	COG3307	-O-antigen
BCS7_RS00640	COG0859	PFAM glycosyl transferase family 9
BCS7_RS00650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCS7_RS00655	COG0156	8-amino-7-oxononanoate synthase activity
BCS7_RS00665	COG2861	carbohydrate metabolic process
BCS7_RS00670	COG4942	peptidase
BCS7_RS00675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCS7_RS00680	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BCS7_RS00685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BCS7_RS00690	COG1045	serine acetyltransferase
BCS7_RS00705	COG0583	DNA-binding transcription factor activity
BCS7_RS00710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BCS7_RS00715	COG0840	transmembrane signaling receptor activity
BCS7_RS00720	COG0840	transmembrane signaling receptor activity
BCS7_RS00725	COG0412	Dienelactone hydrolase
BCS7_RS00740	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BCS7_RS00745	COG2190	(PTS) system
BCS7_RS00745	COG1263	PTS System
BCS7_RS00745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCS7_RS00755	COG4948	Mandelate Racemase Muconate Lactonizing
BCS7_RS00760	COG2188	Transcriptional regulator
BCS7_RS00765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCS7_RS00770	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BCS7_RS00775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BCS7_RS00780	COG0165	Argininosuccinate lyase
BCS7_RS00785	COG1322	Protein conserved in bacteria
BCS7_RS00790	COG2226	methyltransferase
BCS7_RS00800	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BCS7_RS00805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCS7_RS00810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCS7_RS00815	COG0805	protein transport
BCS7_RS00820	COG0084	hydrolase, TatD family'
BCS7_RS00830	COG0250	Participates in transcription elongation, termination and antitermination
BCS7_RS00835	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BCS7_RS00845	COG0183	Belongs to the thiolase family
BCS7_RS00850	COG1024	Enoyl-CoA hydratase
BCS7_RS00850	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCS7_RS00855	COG0006	proline dipeptidase activity
BCS7_RS00860	COG1739	Uncharacterized protein family UPF0029
BCS7_RS00900	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BCS7_RS00905	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BCS7_RS00905	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BCS7_RS00910	COG1072	(Pantothenic acid kinase))
BCS7_RS00950	COG0250	Participates in transcription elongation, termination and antitermination
BCS7_RS00955	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BCS7_RS00960	COG0081	regulation of translation
BCS7_RS00965	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BCS7_RS00970	COG0222	ribosome binding
BCS7_RS00975	COG0085	RNA polymerase activity
BCS7_RS00980	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BCS7_RS00990	COG5457	Domain of unknown function (DUF1127)
BCS7_RS00995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCS7_RS01005	COG2022	thiamine diphosphate biosynthetic process
BCS7_RS01010	COG2104	thiamine diphosphate biosynthetic process
BCS7_RS01015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCS7_RS01020	COG0352	thiamine-phosphate diphosphorylase activity
BCS7_RS01025	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BCS7_RS01030	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BCS7_RS01035	COG2816	NAD+ diphosphatase activity
BCS7_RS01040	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BCS7_RS01045	COG1515	deoxyribonuclease V activity
BCS7_RS01065	COG0151	Belongs to the GarS family
BCS7_RS01070	COG0138	bifunctional purine biosynthesis protein purh
BCS7_RS01095	COG1126	abc transporter atp-binding protein
BCS7_RS01100	COG0765	amino acid transport
BCS7_RS01105	COG4597	amino acid ABC transporter
BCS7_RS01110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCS7_RS01115	COG0765	amino acid transport
BCS7_RS01120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCS7_RS01155	COG4964	Belongs to the GSP D family
BCS7_RS01245	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BCS7_RS01265	COG2264	protein methyltransferase activity
BCS7_RS01270	COG4145	pantothenate transmembrane transporter activity
BCS7_RS01275	COG3924	membrane
BCS7_RS01280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCS7_RS01285	COG2207	Transcriptional regulator
BCS7_RS01290	COG0439	Biotin carboxylase
BCS7_RS01295	COG0511	ligase activity, forming carbon-carbon bonds
BCS7_RS01300	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BCS7_RS01305	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BCS7_RS01310	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BCS7_RS01315	COG0604	alcohol dehydrogenase
BCS7_RS01325	COG1077	Cell shape determining protein MreB Mrl
BCS7_RS01330	COG1792	Involved in formation and maintenance of cell shape
BCS7_RS01335	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BCS7_RS01340	COG0424	maF-like protein
BCS7_RS01345	COG1530	ribonuclease E activity
BCS7_RS01350	COG3164	Protein of unknown function
BCS7_RS01355	COG0312	modulator of DNA gyrase
BCS7_RS01370	COG0583	DNA-binding transcription factor activity
BCS7_RS01380	COG1566	PFAM secretion protein HlyD family protein
BCS7_RS01385	COG1289	transmembrane transporter activity
BCS7_RS01395	COG3028	Belongs to the UPF0307 family
BCS7_RS01400	COG0312	modulator of DNA gyrase
BCS7_RS01405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCS7_RS01410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCS7_RS01415	COG1660	Displays ATPase and GTPase activities
BCS7_RS01420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCS7_RS01425	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BCS7_RS01430	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BCS7_RS01435	COG1137	ATPase activity
BCS7_RS01440	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BCS7_RS01445	COG3117	lipopolysaccharide transmembrane transporter activity
BCS7_RS01450	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BCS7_RS01455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BCS7_RS01455	COG0517	IMP dehydrogenase activity
BCS7_RS01460	COG0530	calcium, potassium:sodium antiporter activity
BCS7_RS01465	COG1127	ABC transporter
BCS7_RS01470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BCS7_RS01475	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BCS7_RS01485	COG3113	response to antibiotic
BCS7_RS01495	COG5007	Belongs to the BolA IbaG family
BCS7_RS01500	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BCS7_RS01505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCS7_RS01510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCS7_RS01515	COG3105	Protein conserved in bacteria
BCS7_RS01520	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BCS7_RS01525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BCS7_RS01530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BCS7_RS01535	COG0625	glutathione transferase activity
BCS7_RS01540	COG2969	positive regulation of protein catabolic process
BCS7_RS01550	COG0493	'glutamate synthase
BCS7_RS01555	COG0067	glutamate synthase
BCS7_RS01555	COG0069	glutamate synthase activity
BCS7_RS01555	COG0070	glutamate synthase
BCS7_RS01560	COG1242	4 iron, 4 sulfur cluster binding
BCS7_RS01565	COG5002	protein histidine kinase activity
BCS7_RS01565	COG2198	Histidine kinase
BCS7_RS01565	COG0784	Response regulator, receiver
BCS7_RS01570	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BCS7_RS01575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCS7_RS01585	COG2823	Periplasmic or secreted lipoprotein
BCS7_RS01590	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BCS7_RS01595	COG0792	nuclease activity
BCS7_RS01600	COG3107	peptidoglycan biosynthetic process
BCS7_RS01605	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BCS7_RS01625	COG3384	dioxygenase
BCS7_RS01630	COG0754	glutathionylspermidine amidase activity
BCS7_RS01635	COG5463	Belongs to the UPF0441 family
BCS7_RS01640	COG1538	Outer membrane efflux protein
BCS7_RS01645	COG0494	nUDIX hydrolase
BCS7_RS01650	COG3151	Protein conserved in bacteria
BCS7_RS01655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BCS7_RS01660	COG3150	esterase
BCS7_RS01675	COG2368	4-hydroxyphenylacetate
BCS7_RS01680	COG0494	nUDIX hydrolase
BCS7_RS01695	COG0167	dihydroorotate dehydrogenase activity
BCS7_RS01700	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BCS7_RS01715	COG0583	DNA-binding transcription factor activity
BCS7_RS01720	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCS7_RS01725	COG1629	transport
BCS7_RS01725	COG4771	TonB-dependent receptor
BCS7_RS01745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCS7_RS01750	COG0204	Acyl-transferase
BCS7_RS01755	COG2132	Multicopper oxidase
BCS7_RS01760	COG2188	Transcriptional regulator
BCS7_RS01765	COG0656	L-ascorbic acid biosynthetic process
BCS7_RS01770	COG1979	alcohol dehydrogenase
BCS7_RS01775	COG0778	Nitroreductase
BCS7_RS01780	COG2207	Transcriptional regulator
BCS7_RS01785	COG0586	Pfam SNARE associated Golgi protein
BCS7_RS01805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BCS7_RS01815	COG0848	biopolymer transport protein
BCS7_RS01855	COG1203	CRISPR-associated helicase, Cas3
BCS7_RS01880	COG1857	crispr-associated protein
BCS7_RS01895	COG1518	maintenance of DNA repeat elements
BCS7_RS01900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCS7_RS01910	COG0076	glutamate decarboxylase activity
BCS7_RS01915	COG2814	Major facilitator Superfamily
BCS7_RS01925	COG3787	Belongs to the UPF0306 family
BCS7_RS01930	COG0702	epimerase
BCS7_RS01960	COG2308	Evidence 4 Homologs of previously reported genes of
BCS7_RS01970	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BCS7_RS01975	COG0540	Belongs to the ATCase OTCase family
BCS7_RS01980	COG2731	YhcH YjgK YiaL family protein
BCS7_RS01985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BCS7_RS01990	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BCS7_RS02005	COG0501	Belongs to the peptidase M48B family
BCS7_RS02010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCS7_RS02015	COG0840	transmembrane signaling receptor activity
BCS7_RS02020	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BCS7_RS02025	COG0525	valine-tRNA ligase activity
BCS7_RS02030	COG2927	DNA polymerase III (CHI subunit)
BCS7_RS02035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCS7_RS02040	COG0795	lipopolysaccharide-transporting ATPase activity
BCS7_RS02045	COG0795	lipopolysaccharide-transporting ATPase activity
BCS7_RS02055	COG0582	viral genome integration into host DNA
BCS7_RS02125	COG2026	Addiction module toxin, RelE StbE family
BCS7_RS02135	COG2850	peptidyl-arginine hydroxylation
BCS7_RS02155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCS7_RS02175	COG0583	DNA-binding transcription factor activity
BCS7_RS02210	COG4650	regulator
BCS7_RS02215	COG1690	Belongs to the RtcB family
BCS7_RS02220	COG3541	Predicted nucleotidyltransferase
BCS7_RS02240	COG1396	sequence-specific DNA binding
BCS7_RS02245	COG3550	peptidyl-serine autophosphorylation
BCS7_RS02250	COG0659	secondary active sulfate transmembrane transporter activity
BCS7_RS02255	COG0288	reversible hydration of carbon dioxide
BCS7_RS02260	COG0840	transmembrane signaling receptor activity
BCS7_RS02275	COG3254	rhamnose metabolic process
BCS7_RS02280	COG0235	Class ii aldolase
BCS7_RS02285	COG4806	L-rhamnose isomerase
BCS7_RS02290	COG1070	Carbohydrate kinase
BCS7_RS02295	COG1917	Cupin 2, conserved barrel domain protein
BCS7_RS02295	COG2169	Transcriptional regulator
BCS7_RS02300	COG1917	Cupin 2, conserved barrel domain protein
BCS7_RS02300	COG4977	sequence-specific DNA binding
BCS7_RS02320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCS7_RS02330	COG0747	negative chemotaxis
BCS7_RS02335	COG3477	response to acidic pH
BCS7_RS02365	COG2862	Uncharacterized protein family, UPF0114
BCS7_RS02370	COG2130	NADP-dependent
BCS7_RS02400	COG3157	Type VI secretion system effector, Hcp
BCS7_RS02405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCS7_RS02410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCS7_RS02415	COG0006	proline dipeptidase activity
BCS7_RS02425	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BCS7_RS02435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCS7_RS02450	COG0560	Phosphoserine phosphatase
BCS7_RS02455	COG3726	membrane protein affecting hemolysin expression
BCS7_RS02465	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BCS7_RS02470	COG2823	Periplasmic or secreted lipoprotein
BCS7_RS02475	COG5487	UPF0391 membrane protein
BCS7_RS02485	COG0084	hydrolase, TatD family'
BCS7_RS02490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCS7_RS02500	COG4771	TonB-dependent receptor
BCS7_RS02510	COG1169	isochorismate synthase
BCS7_RS02515	COG1021	2,3-dihydroxybenzoate-AMP ligase
BCS7_RS02520	COG1535	isochorismatase
BCS7_RS02520	COG3433	isochorismatase activity
BCS7_RS02525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCS7_RS02530	COG1028	Short-chain dehydrogenase reductase Sdr
BCS7_RS02580	COG4107	phosphonate C-P lyase system protein PhnK
BCS7_RS02610	COG3423	Transcriptional regulator
BCS7_RS02630	COG1309	transcriptional regulator
BCS7_RS02635	COG4232	protein-disulfide reductase activity
BCS7_RS02640	COG1324	tolerance protein
BCS7_RS02645	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BCS7_RS02660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BCS7_RS02665	COG0459	protein refolding
BCS7_RS02675	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BCS7_RS02680	COG2937	Belongs to the GPAT DAPAT family
BCS7_RS02685	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCS7_RS02695	COG3237	CsbD-like
BCS7_RS02700	COG0735	belongs to the Fur family
BCS7_RS02705	COG1741	Belongs to the pirin family
BCS7_RS02710	COG0583	DNA-binding transcription factor activity
BCS7_RS02715	COG0435	Glutathione S-transferase
BCS7_RS02720	COG2259	Doxx family
BCS7_RS02730	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BCS7_RS02735	COG4575	ribosome binding
BCS7_RS02740	COG1422	Protein of unknown function (DUF1090)
BCS7_RS02750	COG0586	Pfam SNARE associated Golgi protein
BCS7_RS02760	COG2271	Major facilitator Superfamily
BCS7_RS02765	COG1904	glucuronate isomerase
BCS7_RS02770	COG0246	Mannitol dehydrogenase
BCS7_RS02775	COG2721	sulfolactate sulfo-lyase activity
BCS7_RS02785	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BCS7_RS02790	COG0861	Integral membrane protein TerC family
BCS7_RS02795	COG0673	inositol 2-dehydrogenase activity
BCS7_RS02800	COG2813	Specifically methylates the guanine in position
BCS7_RS02805	COG0446	pyridine nucleotide-disulphide oxidoreductase
BCS7_RS02805	COG1902	pentaerythritol trinitrate reductase activity
BCS7_RS02815	COG3678	ATP-independent chaperone mediated protein folding
BCS7_RS02820	COG2199	diguanylate cyclase activity
BCS7_RS02870	COG3663	DNA glycosylase
BCS7_RS02880	COG0358	DNA primase activity
BCS7_RS02885	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BCS7_RS02890	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BCS7_RS02895	COG1438	arginine binding
BCS7_RS02900	COG0039	L-malate dehydrogenase activity
BCS7_RS02910	COG3423	Transcriptional regulator
BCS7_RS02925	COG0142	geranyltranstransferase activity
BCS7_RS02930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BCS7_RS02935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BCS7_RS02940	COG0697	spore germination
BCS7_RS02945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BCS7_RS02950	COG2027	D-alanyl-D-alanine carboxypeptidase
BCS7_RS02960	COG1534	Rna-binding protein
BCS7_RS02965	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BCS7_RS02970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCS7_RS02975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCS7_RS02980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCS7_RS02990	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCS7_RS03000	COG2130	NADP-dependent
BCS7_RS03060	COG2197	response regulator
BCS7_RS03070	COG0779	Required for maturation of 30S ribosomal subunits
BCS7_RS03080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BCS7_RS03085	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BCS7_RS03090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BCS7_RS03095	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BCS7_RS03100	COG1185	polyribonucleotide nucleotidyltransferase activity
BCS7_RS03110	COG0513	Belongs to the DEAD box helicase family
BCS7_RS03115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCS7_RS03125	COG0826	peptidase U32
BCS7_RS03130	COG0826	peptidase U32
BCS7_RS03135	COG3154	lipid carrier protein
BCS7_RS03140	COG3153	acetyltransferase
BCS7_RS03145	COG2827	Endonuclease containing a URI domain
BCS7_RS03150	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BCS7_RS03155	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BCS7_RS03160	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BCS7_RS03165	COG0813	purine-nucleoside phosphorylase activity
BCS7_RS03170	COG4178	(ABC) transporter
BCS7_RS03180	COG3712	iron ion homeostasis
BCS7_RS03185	COG1595	DNA-templated transcription, initiation
BCS7_RS03200	COG0456	acetyltransferase
BCS7_RS03205	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BCS7_RS03210	COG2813	Specifically methylates the guanine in position
BCS7_RS03215	COG0656	L-ascorbic acid biosynthetic process
BCS7_RS03265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BCS7_RS03270	COG0509	glycine decarboxylation via glycine cleavage system
BCS7_RS03275	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCS7_RS03275	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCS7_RS03280	COG1733	regulation of RNA biosynthetic process
BCS7_RS03285	COG1028	Short-chain dehydrogenase reductase Sdr
BCS7_RS03300	COG1272	protein, Hemolysin III
BCS7_RS03305	COG0354	folic acid binding
BCS7_RS03310	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BCS7_RS03320	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BCS7_RS03325	COG0716	FMN binding
BCS7_RS03330	COG0477	Major facilitator Superfamily
BCS7_RS03340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCS7_RS03345	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCS7_RS03355	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BCS7_RS03375	COG0582	viral genome integration into host DNA
BCS7_RS03385	COG3157	Type VI secretion system effector, Hcp
BCS7_RS03415	COG4319	ketosteroid isomerase
BCS7_RS03425	COG1560	Kdo2-lipid A biosynthetic process
BCS7_RS03435	COG2252	PERMEase
BCS7_RS03440	COG0025	NhaP-type Na H and K H
BCS7_RS03450	COG3850	Histidine kinase
BCS7_RS03450	COG5002	protein histidine kinase activity
BCS7_RS03470	COG4964	Belongs to the GSP D family
BCS7_RS03550	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCS7_RS03555	COG3162	membrane
BCS7_RS03560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCS7_RS03570	COG4774	siderophore transport
BCS7_RS03580	COG3712	iron ion homeostasis
BCS7_RS03600	COG0246	Mannitol dehydrogenase
BCS7_RS03605	COG2873	o-acetylhomoserine
BCS7_RS03610	COG1376	ErfK ybiS ycfS ynhG family protein
BCS7_RS03615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCS7_RS03620	COG3038	cytochrome b561
BCS7_RS03625	COG0674	pyruvate-flavodoxin oxidoreductase activity
BCS7_RS03625	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BCS7_RS03625	COG1013	pyruvate-flavodoxin oxidoreductase activity
BCS7_RS03625	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCS7_RS03640	COG1280	lysine exporter protein (LysE YggA)
BCS7_RS03670	COG4453	Protein conserved in bacteria
BCS7_RS03760	COG3423	Transcriptional regulator
BCS7_RS03775	COG0582	viral genome integration into host DNA
BCS7_RS03785	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BCS7_RS03790	COG2867	negative regulation of translational initiation
BCS7_RS03795	COG2914	Belongs to the UPF0125 (RnfH) family
BCS7_RS03805	COG0497	DNA recombination
BCS7_RS03810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BCS7_RS03815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BCS7_RS03820	COG1914	H( )-stimulated, divalent metal cation uptake system
BCS7_RS03830	COG0477	Major facilitator Superfamily
BCS7_RS03840	COG0494	nUDIX hydrolase
BCS7_RS03875	COG1609	Transcriptional regulator
BCS7_RS03880	COG1126	abc transporter atp-binding protein
BCS7_RS03885	COG0765	amino acid transport
BCS7_RS03895	COG3711	transcriptional antiterminator
BCS7_RS03900	COG2723	6-phospho-beta-galactosidase activity
BCS7_RS03905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCS7_RS03905	COG1263	PTS System
BCS7_RS03905	COG2190	(PTS) system
BCS7_RS03910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCS7_RS03915	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCS7_RS03920	COG0698	ribose 5-phosphate isomerase
BCS7_RS03940	COG1082	Xylose isomerase domain protein TIM barrel
BCS7_RS03945	COG2084	Dehydrogenase
BCS7_RS03965	COG0814	amino acid
BCS7_RS03970	COG1671	Belongs to the UPF0178 family
BCS7_RS03975	COG0408	coproporphyrinogen oxidase activity
BCS7_RS03980	COG0456	acetyltransferase
BCS7_RS03990	COG4771	TonB-dependent receptor
BCS7_RS03995	COG0612	Peptidase, M16
BCS7_RS04000	COG4178	(ABC) transporter
BCS7_RS04010	COG2837	iron assimilation
BCS7_RS04015	COG4150	thiosulfate binding
BCS7_RS04020	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BCS7_RS04025	COG4208	sulfate ABC transporter
BCS7_RS04030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCS7_RS04035	COG0577	efflux transmembrane transporter activity
BCS7_RS04035	COG1136	(ABC) transporter
BCS7_RS04040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCS7_RS04045	COG0745	RESPONSE REGULATOR receiver
BCS7_RS04050	COG2205	protein histidine kinase activity
BCS7_RS04055	COG2190	(PTS) system
BCS7_RS04065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCS7_RS04075	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BCS7_RS04080	COG3115	cell septum assembly
BCS7_RS04085	COG0531	amino acid
BCS7_RS04095	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCS7_RS04105	COG0446	pyridine nucleotide-disulphide oxidoreductase
BCS7_RS04115	COG3604	Transcriptional regulator
BCS7_RS04120	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BCS7_RS04120	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BCS7_RS04150	COG0583	DNA-binding transcription factor activity
BCS7_RS04165	COG1522	sequence-specific DNA binding
BCS7_RS04180	COG3976	FMN-binding domain protein
BCS7_RS04180	COG1053	succinate dehydrogenase
BCS7_RS04180	COG0431	NADPH-dependent FMN reductase
BCS7_RS04185	COG0477	Major facilitator Superfamily
BCS7_RS04190	COG3301	Polysulphide reductase, NrfD
BCS7_RS04195	COG0437	4 iron, 4 sulfur cluster binding
BCS7_RS04210	COG0583	DNA-binding transcription factor activity
BCS7_RS04225	COG4948	Mandelate Racemase Muconate Lactonizing
BCS7_RS04230	COG1063	alcohol dehydrogenase
BCS7_RS04235	COG0477	Major facilitator Superfamily
BCS7_RS04240	COG0246	Mannitol dehydrogenase
BCS7_RS04245	COG1802	Transcriptional regulator
BCS7_RS04260	COG0811	peptide transport
BCS7_RS04310	COG0583	DNA-binding transcription factor activity
BCS7_RS04325	COG4948	Mandelate Racemase Muconate Lactonizing
BCS7_RS04335	COG1129	ABC transporter
BCS7_RS04390	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCS7_RS04410	COG2814	Major facilitator Superfamily
BCS7_RS04430	COG2801	Transposase and inactivated derivatives
BCS7_RS04580	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCS7_RS04585	COG3118	belongs to the thioredoxin family
BCS7_RS04590	COG1902	pentaerythritol trinitrate reductase activity
BCS7_RS04600	COG1028	Short-chain dehydrogenase reductase Sdr
BCS7_RS04625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCS7_RS04770	COG0297	glycogen (starch) synthase activity
BCS7_RS04790	COG1045	serine acetyltransferase
BCS7_RS04810	COG3423	Transcriptional regulator
BCS7_RS04825	COG0583	DNA-binding transcription factor activity
BCS7_RS04840	COG0583	DNA-binding transcription factor activity
BCS7_RS04850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BCS7_RS04850	COG0473	3-isopropylmalate dehydrogenase activity
BCS7_RS04865	COG2267	carboxylic ester hydrolase activity
BCS7_RS04890	COG1982	Orn Lys Arg decarboxylase major
BCS7_RS04895	COG1113	amino acid transport
BCS7_RS04910	COG5441	Belongs to the UPF0261 family
BCS7_RS04915	COG5564	TIM-barrel signal transduction protein
BCS7_RS04925	COG2169	Transcriptional regulator
BCS7_RS04925	COG1917	Cupin 2, conserved barrel domain protein
BCS7_RS04930	COG0741	lytic transglycosylase activity
BCS7_RS04935	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BCS7_RS04945	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BCS7_RS04950	COG3171	Protein conserved in bacteria
BCS7_RS04960	COG0667	Aldo Keto reductase
BCS7_RS04975	COG0861	Integral membrane protein TerC family
BCS7_RS04980	COG3066	DNA modification
BCS7_RS04985	COG0494	nUDIX hydrolase
BCS7_RS04995	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BCS7_RS05000	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BCS7_RS05005	COG4969	Belongs to the N-Me-Phe pilin family
BCS7_RS05010	COG4795	General secretion pathway protein
BCS7_RS05025	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BCS7_RS05030	COG1025	Belongs to the peptidase M16 family
BCS7_RS05045	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BCS7_RS05045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BCS7_RS05070	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BCS7_RS05075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCS7_RS05085	COG1473	amidohydrolase
BCS7_RS05090	COG4172	Belongs to the ABC transporter superfamily
BCS7_RS05095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCS7_RS05105	COG0747	negative chemotaxis
BCS7_RS05115	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCS7_RS05120	COG2166	iron-sulfur cluster assembly
BCS7_RS05125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCS7_RS05135	COG0583	DNA-binding transcription factor activity
BCS7_RS05140	COG2363	Small membrane protein
BCS7_RS05145	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BCS7_RS05150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCS7_RS05155	COG1611	Belongs to the LOG family
BCS7_RS05160	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCS7_RS05160	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCS7_RS05190	COG2171	N-acyltransferase activity
BCS7_RS05195	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BCS7_RS05205	COG0052	Belongs to the universal ribosomal protein uS2 family
BCS7_RS05210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BCS7_RS05215	COG0528	UMP kinase activity
BCS7_RS05220	COG0233	cytoplasmic translational termination
BCS7_RS05230	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BCS7_RS05235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BCS7_RS05240	COG0575	Belongs to the CDS family
BCS7_RS05245	COG0750	zinc metalloprotease
BCS7_RS05250	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCS7_RS05255	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BCS7_RS05260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCS7_RS05265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCS7_RS05270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCS7_RS05275	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCS7_RS05280	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BCS7_RS05285	COG0587	DNA-directed DNA polymerase activity
BCS7_RS05290	COG0825	malonyl-CoA metabolic process
BCS7_RS05295	COG0346	lactoylglutathione lyase activity
BCS7_RS05300	COG0037	tRNA processing
BCS7_RS05305	COG4568	rho-dependent transcription termination
BCS7_RS05320	COG3015	lipoprotein NlpE involved in copper resistance
BCS7_RS05325	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BCS7_RS05335	COG2848	UPF0210 protein
BCS7_RS05345	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BCS7_RS05350	COG2824	Alkylphosphonate utilization operon protein PhnA
BCS7_RS05355	COG2951	lytic endotransglycosylase activity
BCS7_RS05365	COG0583	DNA-binding transcription factor activity
BCS7_RS05395	COG2186	Transcriptional regulator
BCS7_RS05400	COG1312	Catalyzes the dehydration of D-mannonate
BCS7_RS05405	COG5297	Belongs to the glycosyl hydrolase family 6
BCS7_RS05420	COG1132	(ABC) transporter
BCS7_RS05440	COG4615	Cyclic peptide transporter
BCS7_RS05450	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BCS7_RS05455	COG3123	guanosine phosphorylase activity
BCS7_RS05470	COG2974	May be involved in recombination
BCS7_RS05475	COG1940	carbohydrate kinase activity
BCS7_RS05505	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BCS7_RS05525	COG0668	transmembrane transport
BCS7_RS05530	COG0450	alkyl hydroperoxide reductase
BCS7_RS05535	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BCS7_RS05540	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BCS7_RS05545	COG0343	queuine tRNA-ribosyltransferase activity
BCS7_RS05550	COG1862	Preprotein translocase
BCS7_RS05555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCS7_RS05565	COG4238	major outer membrane lipoprotein
BCS7_RS05570	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BCS7_RS05575	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCS7_RS05575	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCS7_RS05580	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BCS7_RS05585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCS7_RS05590	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BCS7_RS05595	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BCS7_RS05600	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BCS7_RS05605	COG0142	geranyltranstransferase activity
BCS7_RS05615	COG0301	tRNA thio-modification
BCS7_RS05615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCS7_RS05630	COG1666	GTP binding
BCS7_RS05635	COG2814	Major facilitator Superfamily
BCS7_RS05640	COG0109	protoheme IX farnesyltransferase activity
BCS7_RS05645	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCS7_RS05650	COG1845	cytochrome c oxidase, subunit III
BCS7_RS05655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCS7_RS05660	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCS7_RS05665	COG2223	nitrite transmembrane transporter activity
BCS7_RS05670	COG3056	Lipoprotein
BCS7_RS05675	COG0271	Belongs to the BolA IbaG family
BCS7_RS05680	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCS7_RS05685	COG0740	serine-type endopeptidase activity
BCS7_RS05690	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BCS7_RS05695	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BCS7_RS05700	COG0776	regulation of translation
BCS7_RS05710	COG1555	photosystem II stabilization
BCS7_RS05715	COG0824	Thioesterase
BCS7_RS05720	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BCS7_RS05725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCS7_RS05735	COG1522	sequence-specific DNA binding
BCS7_RS05740	COG1132	(ABC) transporter
BCS7_RS05745	COG1132	(ABC) transporter
BCS7_RS05755	COG0347	Belongs to the P(II) protein family
BCS7_RS05760	COG0004	ammonium transporteR
BCS7_RS05765	COG1946	Acyl-CoA thioesterase
BCS7_RS05770	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BCS7_RS05775	COG3695	enzyme binding
BCS7_RS05795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BCS7_RS05800	COG0254	rRNA binding
BCS7_RS05805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCS7_RS05810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCS7_RS05815	COG1309	transcriptional regulator
BCS7_RS05830	COG2832	Protein of unknown function (DUF454)
BCS7_RS05835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCS7_RS05840	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BCS7_RS05845	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BCS7_RS05850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BCS7_RS05855	COG0326	Molecular chaperone. Has ATPase activity
BCS7_RS05860	COG0563	adenylate kinase activity
BCS7_RS05865	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BCS7_RS05875	COG0737	Belongs to the 5'-nucleotidase family
BCS7_RS05895	COG1966	Carbon starvation protein
BCS7_RS05900	COG2879	small protein
BCS7_RS05905	COG0523	cobalamin synthesis protein
BCS7_RS05910	COG5434	Belongs to the glycosyl hydrolase 28 family
BCS7_RS05920	COG3735	TraB family
BCS7_RS05935	COG1585	Membrane protein implicated in regulation of membrane protease activity
BCS7_RS05940	COG0330	HflC and HflK could
BCS7_RS05945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCS7_RS05950	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCS7_RS05955	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCS7_RS05960	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCS7_RS05970	COG0784	Response regulator, receiver
BCS7_RS05970	COG2205	protein histidine kinase activity
BCS7_RS05975	COG2197	response regulator
BCS7_RS05980	COG2198	Histidine kinase
BCS7_RS05980	COG0642	Histidine kinase
BCS7_RS05985	COG2223	nitrite transmembrane transporter activity
BCS7_RS05990	COG1169	isochorismate synthase
BCS7_RS05995	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BCS7_RS06000	COG0596	Alpha beta hydrolase
BCS7_RS06005	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BCS7_RS06010	COG1441	menaquinone biosynthetic process
BCS7_RS06030	COG0814	amino acid
BCS7_RS06045	COG3118	belongs to the thioredoxin family
BCS7_RS06050	COG0300	oxidoreductase activity
BCS7_RS06055	COG2755	lipolytic protein G-D-S-L family
BCS7_RS06060	COG4181	ATPase activity
BCS7_RS06065	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BCS7_RS06070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCS7_RS06075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCS7_RS06080	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BCS7_RS06085	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BCS7_RS06090	COG2233	PERMEase
BCS7_RS06095	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BCS7_RS06100	COG1393	Belongs to the ArsC family
BCS7_RS06105	COG4783	chaperone-mediated protein folding
BCS7_RS06120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BCS7_RS06125	COG2716	regulation of RNA biosynthetic process
BCS7_RS06135	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BCS7_RS06140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BCS7_RS06145	COG2707	UPF0756 membrane protein
BCS7_RS06150	COG1444	tRNA N-acetyltransferase activity
BCS7_RS06160	COG3118	belongs to the thioredoxin family
BCS7_RS06185	COG1595	DNA-templated transcription, initiation
BCS7_RS06195	COG4774	siderophore transport
BCS7_RS06200	COG4178	(ABC) transporter
BCS7_RS06215	COG3813	Protein conserved in bacteria
BCS7_RS06220	COG0400	carboxylic ester hydrolase activity
BCS7_RS06235	COG1876	peptidase activity
BCS7_RS06240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCS7_RS06245	COG1393	Belongs to the ArsC family
BCS7_RS06250	COG1794	racemase activity, acting on amino acids and derivatives
BCS7_RS06260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BCS7_RS06270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCS7_RS06275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BCS7_RS06280	COG0321	lipoyl(octanoyl) transferase activity
BCS7_RS06285	COG2921	Belongs to the UPF0250 family
BCS7_RS06290	COG1686	Belongs to the peptidase S11 family
BCS7_RS06295	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BCS7_RS06300	COG0772	Belongs to the SEDS family
BCS7_RS06305	COG0768	penicillin binding
BCS7_RS06310	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BCS7_RS06315	COG0799	negative regulation of ribosome biogenesis
BCS7_RS06320	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BCS7_RS06325	COG1466	dna polymerase III delta subunit
BCS7_RS06330	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BCS7_RS06335	COG0495	leucyl-tRNA aminoacylation
BCS7_RS06340	COG2888	peptidyl-tyrosine sulfation
BCS7_RS06345	COG1126	abc transporter atp-binding protein
BCS7_RS06350	COG0765	amino acid transport
BCS7_RS06355	COG0765	amino acid transport
BCS7_RS06370	COG4535	Mg2 and Co2 transporter CorC
BCS7_RS06375	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BCS7_RS06380	COG1702	phosphate starvation-inducible protein PhoH
BCS7_RS06385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCS7_RS06390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCS7_RS06435	COG0367	asparagine synthase
BCS7_RS06440	COG1940	carbohydrate kinase activity
BCS7_RS06440	COG1846	Transcriptional regulator
BCS7_RS06445	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCS7_RS06450	COG0363	glucosamine-6-phosphate deaminase activity
BCS7_RS06455	COG2190	(PTS) system
BCS7_RS06455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCS7_RS06455	COG1263	PTS System
BCS7_RS06460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCS7_RS06465	COG0735	belongs to the Fur family
BCS7_RS06470	COG0716	FMN binding
BCS7_RS06490	COG0596	Alpha beta hydrolase
BCS7_RS06495	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BCS7_RS06500	COG0033	Phosphoglucomutase
BCS7_RS06515	COG2205	protein histidine kinase activity
BCS7_RS06520	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BCS7_RS06525	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BCS7_RS06530	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BCS7_RS06545	COG3272	Protein of unknown function (DUF1722)
BCS7_RS06550	COG0415	Belongs to the DNA photolyase family
BCS7_RS06560	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BCS7_RS06570	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BCS7_RS06575	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BCS7_RS06580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCS7_RS06600	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BCS7_RS06605	COG1053	succinate dehydrogenase
BCS7_RS06610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCS7_RS06615	COG0567	Dehydrogenase, E1 component
BCS7_RS06620	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCS7_RS06625	COG0045	succinate-CoA ligase (ADP-forming) activity
BCS7_RS06630	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCS7_RS06640	COG1271	oxidase subunit
BCS7_RS06645	COG1294	oxidase, subunit
BCS7_RS06650	COG4890	Cyd operon protein YbgT
BCS7_RS06655	COG3790	cyd operon protein YbgE
BCS7_RS06660	COG0824	Thioesterase
BCS7_RS06665	COG0811	peptide transport
BCS7_RS06670	COG0848	biopolymer transport protein
BCS7_RS06680	COG0823	Involved in the tonB-independent uptake of proteins
BCS7_RS06685	COG2885	chlorophyll binding
BCS7_RS06690	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BCS7_RS06710	COG1811	Na channel or pump
BCS7_RS06720	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BCS7_RS06735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCS7_RS06740	COG0588	phosphoglycerate mutase activity
BCS7_RS06745	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCS7_RS06750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCS7_RS06770	COG2017	converts alpha-aldose to the beta-anomer
BCS7_RS06775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCS7_RS06785	COG2005	Transcriptional regulator
BCS7_RS06785	COG3585	molybdate ion transport
BCS7_RS06795	COG0725	ABC transporter, periplasmic molybdate-binding protein
BCS7_RS06800	COG4149	molybdate abc transporter
BCS7_RS06805	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BCS7_RS06825	COG2211	Major facilitator Superfamily
BCS7_RS06835	COG0561	phosphatase activity
BCS7_RS06845	COG2706	6-phosphogluconolactonase activity
BCS7_RS06860	COG0437	4 iron, 4 sulfur cluster binding
BCS7_RS06865	COG3383	formate dehydrogenase (NAD+) activity
BCS7_RS06865	COG0243	molybdopterin cofactor binding
BCS7_RS06870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCS7_RS06870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCS7_RS06885	COG0572	uridine kinase
BCS7_RS06890	COG0717	Belongs to the dCTP deaminase family
BCS7_RS06900	COG3069	C4-dicarboxylate transmembrane transporter activity
BCS7_RS06905	COG1253	flavin adenine dinucleotide binding
BCS7_RS06910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCS7_RS06930	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BCS7_RS06970	COG0438	transferase activity, transferring glycosyl groups
BCS7_RS06980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCS7_RS07000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCS7_RS07030	COG1605	Chorismate mutase
BCS7_RS07045	COG3711	transcriptional antiterminator
BCS7_RS07050	COG3706	GGDEF domain
BCS7_RS07070	COG3962	Belongs to the TPP enzyme family
BCS7_RS07080	COG0673	inositol 2-dehydrogenase activity
BCS7_RS07115	COG3718	enzyme involved in inositol metabolism
BCS7_RS07130	COG1840	ABC-type Fe3 transport system, periplasmic component
BCS7_RS07140	COG2723	6-phospho-beta-galactosidase activity
BCS7_RS07145	COG2190	(PTS) system
BCS7_RS07145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCS7_RS07145	COG1263	PTS System
BCS7_RS07150	COG2203	Gaf domain
BCS7_RS07150	COG2199	diguanylate cyclase activity
BCS7_RS07160	COG3615	Tellurite resistance protein tehB
BCS7_RS07175	COG2223	nitrite transmembrane transporter activity
BCS7_RS07185	COG3250	beta-galactosidase activity
BCS7_RS07190	COG1609	Transcriptional regulator
BCS7_RS07195	COG3842	ATPase activity
BCS7_RS07205	COG1840	ABC-type Fe3 transport system, periplasmic component
BCS7_RS07210	COG2271	Major facilitator Superfamily
BCS7_RS07225	COG1464	Belongs to the NlpA lipoprotein family
BCS7_RS07240	COG0583	DNA-binding transcription factor activity
BCS7_RS07245	COG1301	dicarboxylic acid transport
BCS7_RS07255	COG2851	Citrate transporter
BCS7_RS07260	COG3383	formate dehydrogenase (NAD+) activity
BCS7_RS07265	COG0840	transmembrane signaling receptor activity
BCS7_RS07270	COG0672	)-iron permease
BCS7_RS07285	COG0577	efflux transmembrane transporter activity
BCS7_RS07285	COG1136	(ABC) transporter
BCS7_RS07300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCS7_RS07305	COG0697	spore germination
BCS7_RS07320	COG1301	dicarboxylic acid transport
BCS7_RS07325	COG0371	Dehydrogenase
BCS7_RS07345	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BCS7_RS07355	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BCS7_RS07400	COG1012	belongs to the aldehyde dehydrogenase family
BCS7_RS07405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCS7_RS07410	COG0840	transmembrane signaling receptor activity
BCS7_RS07415	COG2226	methyltransferase
BCS7_RS07425	COG0477	Major facilitator Superfamily
BCS7_RS07440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BCS7_RS07445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCS7_RS07450	COG0747	negative chemotaxis
BCS7_RS07485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCS7_RS07525	COG0784	Response regulator, receiver
BCS7_RS07525	COG0835	chemotaxis
BCS7_RS07530	COG0625	glutathione transferase activity
BCS7_RS07535	COG2910	NAD(P)H-binding
BCS7_RS07540	COG1733	regulation of RNA biosynthetic process
BCS7_RS07550	COG0640	Transcriptional regulator
BCS7_RS07560	COG2814	Major facilitator Superfamily
BCS7_RS07565	COG4978	Transcriptional regulator
BCS7_RS07565	COG0789	Transcriptional regulator
BCS7_RS07570	COG2723	6-phospho-beta-galactosidase activity
BCS7_RS07580	COG3122	Protein conserved in bacteria
BCS7_RS07590	COG2169	Transcriptional regulator
BCS7_RS07590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCS7_RS07675	COG4227	nucleotidyltransferase activity
BCS7_RS07700	COG3228	Belongs to the MtfA family
BCS7_RS07725	COG0401	homolog of Blt101
BCS7_RS07730	COG0471	metal ion transport
BCS7_RS07740	COG2188	Transcriptional regulator
BCS7_RS07745	COG3706	GGDEF domain
BCS7_RS07760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCS7_RS07765	COG0303	'Molybdopterin
BCS7_RS07770	COG4172	Belongs to the ABC transporter superfamily
BCS7_RS07780	COG0601	transmembrane transport
BCS7_RS07785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCS7_RS07795	COG0295	cytidine deaminase activity
BCS7_RS07800	COG1346	cytolysis
BCS7_RS07805	COG1380	Effector of murein hydrolase LrgA
BCS7_RS07810	COG5297	Belongs to the glycosyl hydrolase family 6
BCS7_RS07825	COG0156	8-amino-7-oxononanoate synthase activity
BCS7_RS07830	COG2226	methyltransferase
BCS7_RS07835	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BCS7_RS07860	COG0556	nucleotide-excision repair
BCS7_RS07875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BCS7_RS07880	COG0521	Mo-molybdopterin cofactor biosynthetic process
BCS7_RS07885	COG0315	cyclic pyranopterin monophosphate synthase activity
BCS7_RS07890	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BCS7_RS07895	COG0314	molybdopterin synthase activity
BCS7_RS07900	COG0670	Belongs to the BI1 family
BCS7_RS07905	COG0842	Transport permease protein
BCS7_RS07910	COG0842	Transport permease protein
BCS7_RS07915	COG1131	(ABC) transporter
BCS7_RS07930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCS7_RS07935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCS7_RS07940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCS7_RS07945	COG1120	ATPase activity
BCS7_RS07960	COG0513	Belongs to the DEAD box helicase family
BCS7_RS07975	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCS7_RS07980	COG0747	negative chemotaxis
BCS7_RS07985	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCS7_RS07990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCS7_RS08000	COG0833	amino acid
BCS7_RS08005	COG2040	homocysteine
BCS7_RS08020	COG3976	FMN-binding domain protein
BCS7_RS08020	COG0431	NADPH-dependent FMN reductase
BCS7_RS08020	COG1053	succinate dehydrogenase
BCS7_RS08030	COG1686	Belongs to the peptidase S11 family
BCS7_RS08045	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BCS7_RS08195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCS7_RS08205	COG1126	abc transporter atp-binding protein
BCS7_RS08210	COG0765	amino acid transport
BCS7_RS08215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCS7_RS08220	COG0783	Belongs to the Dps family
BCS7_RS08225	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BCS7_RS08225	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BCS7_RS08235	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BCS7_RS08240	COG2807	transmembrane transport
BCS7_RS08245	COG0534	Mate efflux family protein
BCS7_RS08290	COG0582	viral genome integration into host DNA
BCS7_RS08335	COG0741	lytic transglycosylase activity
BCS7_RS08405	COG3561	AntA/AntB antirepressor
BCS7_RS08430	COG0582	viral genome integration into host DNA
BCS7_RS08440	COG3083	sulfuric ester hydrolase activity
BCS7_RS08445	COG3082	Protein of unknown function (DUF1414)
BCS7_RS08450	COG3081	Nucleoid-associated protein
BCS7_RS08460	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BCS7_RS08480	COG2814	Major facilitator Superfamily
BCS7_RS08490	COG4172	Belongs to the ABC transporter superfamily
BCS7_RS08495	COG4239	(ABC) transporter, permease
BCS7_RS08500	COG4174	ABC transporter (Permease)
BCS7_RS08505	COG4166	transmembrane transport
BCS7_RS08515	COG0625	glutathione transferase activity
BCS7_RS08530	COG0791	NLP P60 protein
BCS7_RS08535	COG0671	phosphoesterase, PA-phosphatase related
BCS7_RS08540	COG0523	cobalamin synthesis protein
BCS7_RS08545	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BCS7_RS08560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCS7_RS08560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCS7_RS08570	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BCS7_RS08570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCS7_RS08570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCS7_RS08575	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BCS7_RS08580	COG2855	membrane
BCS7_RS08585	COG0583	DNA-binding transcription factor activity
BCS7_RS08590	COG0833	amino acid
BCS7_RS08595	COG4771	TonB-dependent receptor
BCS7_RS08600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCS7_RS08605	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCS7_RS08610	COG1129	ABC transporter
BCS7_RS08615	COG0371	Dehydrogenase
BCS7_RS08640	COG0583	DNA-binding transcription factor activity
BCS7_RS08645	COG0840	transmembrane signaling receptor activity
BCS7_RS08650	COG0302	gtp cyclohydrolase
BCS7_RS08660	COG2949	membrane
BCS7_RS08665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCS7_RS08670	COG2133	pyrroloquinoline quinone binding
BCS7_RS08675	COG0625	glutathione transferase activity
BCS7_RS08685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCS7_RS08690	COG2011	ABC-type metal ion transport system permease component
BCS7_RS08695	COG1686	Belongs to the peptidase S11 family
BCS7_RS08700	COG1349	DNA-binding transcription factor activity
BCS7_RS08705	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BCS7_RS08710	COG2985	domain, Protein
BCS7_RS08710	COG0569	domain protein
BCS7_RS08725	COG0778	Nitroreductase
BCS7_RS08740	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BCS7_RS08750	COG1176	ABC-type spermidine putrescine transport system, permease component I
BCS7_RS08755	COG1177	transmembrane transport
BCS7_RS08765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCS7_RS08770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCS7_RS08775	COG4160	amino acid transport
BCS7_RS08780	COG4215	(ABC) transporter
BCS7_RS08785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCS7_RS08790	COG1126	abc transporter atp-binding protein
BCS7_RS08795	COG0393	Putative heavy-metal-binding
BCS7_RS08815	COG3023	N-Acetylmuramoyl-L-alanine amidase
BCS7_RS08825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCS7_RS08830	COG1151	hydroxylamine reductase activity
BCS7_RS08835	COG2431	L-lysine efflux transmembrane transporter activity
BCS7_RS08840	COG3593	DNA synthesis involved in DNA repair
BCS7_RS08845	COG1278	Cold shock
BCS7_RS08855	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BCS7_RS08860	COG0542	response to heat
BCS7_RS08865	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCS7_RS08875	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BCS7_RS08880	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BCS7_RS08885	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BCS7_RS08890	COG4988	ABC transporter
BCS7_RS08895	COG0492	ferredoxin-NADP+ reductase activity
BCS7_RS08905	COG1674	ftsk spoiiie
BCS7_RS08905	COG3107	peptidoglycan biosynthetic process
BCS7_RS08910	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BCS7_RS08915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCS7_RS08920	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BCS7_RS08925	COG0477	Major facilitator Superfamily
BCS7_RS08950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCS7_RS08955	COG1882	Formate acetyltransferase
BCS7_RS08960	COG2116	formate transmembrane transporter activity
BCS7_RS08965	COG1944	ATP diphosphatase activity
BCS7_RS08970	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BCS7_RS08975	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BCS7_RS08980	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BCS7_RS08985	COG0539	negative regulation of cytoplasmic translation
BCS7_RS08990	COG0776	regulation of translation
BCS7_RS08995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BCS7_RS08995	COG0140	phosphoribosyl-ATP diphosphatase activity
BCS7_RS09000	COG0107	imidazoleglycerol-phosphate synthase activity
BCS7_RS09005	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BCS7_RS09010	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BCS7_RS09015	COG0131	Imidazoleglycerol-phosphate dehydratase
BCS7_RS09015	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BCS7_RS09020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BCS7_RS09025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BCS7_RS09030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BCS7_RS09035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCS7_RS09040	COG0840	transmembrane signaling receptor activity
BCS7_RS09050	COG4565	transcriptional regulatory protein
BCS7_RS09060	COG3493	citrate carrier protein
BCS7_RS09070	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCS7_RS09075	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BCS7_RS09080	COG3052	prosthetic group binding
BCS7_RS09100	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BCS7_RS09105	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BCS7_RS09115	COG0531	amino acid
BCS7_RS09120	COG2925	Exonuclease
BCS7_RS09125	COG4607	ABC-type enterochelin transport system periplasmic component
BCS7_RS09135	COG4605	iron ion homeostasis
BCS7_RS09140	COG4604	ABC transporter, ATP-binding protein
BCS7_RS09145	COG2926	Belongs to the UPF0265 family
BCS7_RS09150	COG0658	competence protein
BCS7_RS09150	COG2333	competence protein COMEC
BCS7_RS09155	COG1132	(ABC) transporter
BCS7_RS09160	COG1663	tetraacyldisaccharide 4'-kinase activity
BCS7_RS09165	COG2835	tetraacyldisaccharide 4'-kinase activity
BCS7_RS09170	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BCS7_RS09180	COG3173	Aminoglycoside phosphotransferase
BCS7_RS09185	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BCS7_RS09190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCS7_RS09195	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
BCS7_RS09200	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BCS7_RS09205	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BCS7_RS09210	COG2989	Protein conserved in bacteria
BCS7_RS09215	COG3108	Peptidase M15
BCS7_RS09220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCS7_RS09225	COG1448	Aminotransferase
BCS7_RS09235	COG0017	Asparaginyl-tRNA synthetase
BCS7_RS09240	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BCS7_RS09245	COG0308	aminopeptidase N
BCS7_RS09250	COG0167	dihydroorotate dehydrogenase activity
BCS7_RS09260	COG3217	Mosc domain protein beta barrel domain protein
BCS7_RS09260	COG0633	Ferredoxin
BCS7_RS09265	COG0116	Belongs to the methyltransferase superfamily
BCS7_RS09265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCS7_RS09285	COG3009	Protein conserved in bacteria
BCS7_RS09295	COG3130	regulation of translation
BCS7_RS09300	COG0840	transmembrane signaling receptor activity
BCS7_RS09315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BCS7_RS09320	COG3381	protein complex oligomerization
BCS7_RS09330	COG2999	glutathione oxidoreductase activity
BCS7_RS09335	COG0477	Major facilitator Superfamily
BCS7_RS09340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCS7_RS09345	COG3132	Protein of unknown function, DUF480
BCS7_RS09355	COG0728	peptidoglycan biosynthetic process
BCS7_RS09360	COG0018	arginyl-trna synthetase
BCS7_RS09365	COG3102	Protein conserved in bacteria
BCS7_RS09370	COG3142	Participates in the control of copper homeostasis
BCS7_RS09375	COG0500	methyltransferase
BCS7_RS09380	COG2226	methyltransferase
BCS7_RS09385	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BCS7_RS09390	COG1801	Protein of unknown function DUF72
BCS7_RS09395	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BCS7_RS09400	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BCS7_RS09405	COG0494	nUDIX hydrolase
BCS7_RS09410	COG0217	transcriptional regulatory protein
BCS7_RS09415	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BCS7_RS09420	COG0632	four-way junction helicase activity
BCS7_RS09425	COG2255	four-way junction helicase activity
BCS7_RS09430	COG4580	involved in the transport of maltose and maltodextrins
BCS7_RS09435	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCS7_RS09440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCS7_RS09445	COG1609	Transcriptional regulator
BCS7_RS09450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCS7_RS09455	COG1121	(ABC) transporter
BCS7_RS09460	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BCS7_RS09465	COG0739	heme binding
BCS7_RS09470	COG1560	Kdo2-lipid A biosynthetic process
BCS7_RS09475	COG0469	pyruvate kinase activity
BCS7_RS09480	COG1737	Transcriptional regulator
BCS7_RS09485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCS7_RS09490	COG0800	Aldolase
BCS7_RS09495	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BCS7_RS09510	COG1528	Iron-storage protein
BCS7_RS09580	COG3756	Protein conserved in bacteria
BCS7_RS09675	COG3567	Phage-associated protein, HI1409 family
BCS7_RS09685	COG3566	protein conserved in bacteria
BCS7_RS09835	COG1278	Cold shock
BCS7_RS09860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BCS7_RS09860	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BCS7_RS09865	COG3008	intermembrane lipid transfer
BCS7_RS09870	COG2995	paraquat-inducible protein a
BCS7_RS09875	COG1956	GAF domain-containing protein
BCS7_RS09880	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BCS7_RS09890	COG2207	Transcriptional regulator
BCS7_RS09905	COG1177	transmembrane transport
BCS7_RS09915	COG3842	ATPase activity
BCS7_RS09920	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCS7_RS09925	COG2850	peptidyl-arginine hydroxylation
BCS7_RS09950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BCS7_RS09955	COG2915	High frequency lysogenization protein hflD homolog
BCS7_RS09960	COG0482	sulfurtransferase activity
BCS7_RS09970	COG1187	pseudouridine synthase activity
BCS7_RS09975	COG0538	isocitrate dehydrogenase activity
BCS7_RS10015	COG0348	domain, Protein
BCS7_RS10035	COG3300	MHYT domain
BCS7_RS10035	COG5001	Diguanylate cyclase
BCS7_RS10040	COG3275	phosphorelay sensor kinase activity
BCS7_RS10045	COG3279	Response regulator of the LytR AlgR family
BCS7_RS10050	COG2223	nitrite transmembrane transporter activity
BCS7_RS10065	COG0501	Belongs to the peptidase M48B family
BCS7_RS10070	COG0823	Involved in the tonB-independent uptake of proteins
BCS7_RS10085	COG1113	amino acid transport
BCS7_RS10090	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCS7_RS10095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BCS7_RS10100	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BCS7_RS10105	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BCS7_RS10110	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BCS7_RS10115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCS7_RS10115	COG0072	phenylalanine-tRNA ligase activity
BCS7_RS10120	COG0776	regulation of translation
BCS7_RS10130	COG1132	(ABC) transporter
BCS7_RS10140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BCS7_RS10145	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCS7_RS10150	COG1823	symporter activity
BCS7_RS10160	COG1988	membrane-bound metal-dependent
BCS7_RS10165	COG0657	acetylesterase activity
BCS7_RS10165	COG2755	lipolytic protein G-D-S-L family
BCS7_RS10170	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BCS7_RS10180	COG3842	ATPase activity
BCS7_RS10185	COG0395	ABC-type sugar transport system, permease component
BCS7_RS10190	COG1175	transmembrane transport
BCS7_RS10200	COG1028	Short-chain dehydrogenase reductase Sdr
BCS7_RS10210	COG1917	Cupin 2, conserved barrel domain protein
BCS7_RS10215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCS7_RS10225	COG3001	Fructosamine kinase
BCS7_RS10230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCS7_RS10235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCS7_RS10240	COG1121	(ABC) transporter
BCS7_RS10245	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCS7_RS10260	COG2226	methyltransferase
BCS7_RS10265	COG1971	Probably functions as a manganese efflux pump
BCS7_RS10270	COG4811	Protein of unknown function (DUF986)
BCS7_RS10275	COG3716	PTS system mannose fructose sorbose family IID component
BCS7_RS10280	COG3715	PTS system
BCS7_RS10285	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCS7_RS10285	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCS7_RS10290	COG1253	flavin adenine dinucleotide binding
BCS7_RS10295	COG1760	l-serine dehydratase
BCS7_RS10300	COG0494	nUDIX hydrolase
BCS7_RS10310	COG3140	Belongs to the UPF0181 family
BCS7_RS10315	COG0251	oxidation-reduction process
BCS7_RS10320	COG1199	ATP-dependent helicase activity
BCS7_RS10325	COG1214	PFAM Peptidase M22, glycoprotease
BCS7_RS10330	COG3065	identical protein binding
BCS7_RS10340	COG0318	PFAM AMP-dependent synthetase and ligase
BCS7_RS10345	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BCS7_RS10350	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BCS7_RS10355	COG2894	cell division
BCS7_RS10360	COG0850	regulation of cytokinetic process
BCS7_RS10365	COG3100	YcgL domain-containing protein
BCS7_RS10375	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCS7_RS10380	COG2983	Belongs to the UPF0260 family
BCS7_RS10390	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BCS7_RS10400	COG2186	Transcriptional regulator
BCS7_RS10405	COG2719	SpoVR family
BCS7_RS10440	COG0205	6-phosphofructokinase activity
BCS7_RS10445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCS7_RS10460	COG2718	Belongs to the UPF0229 family
BCS7_RS10465	COG2766	serine protein kinase
BCS7_RS10470	COG3713	MltA-interacting MipA family protein
BCS7_RS10475	COG0656	L-ascorbic acid biosynthetic process
BCS7_RS10495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCS7_RS10500	COG3139	Protein of unknown function (DUF1315)
BCS7_RS10505	COG1335	isochorismatase
BCS7_RS10510	COG0252	asparaginase activity
BCS7_RS10515	COG0616	signal peptide processing
BCS7_RS10525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCS7_RS10535	COG0708	Exodeoxyribonuclease III
BCS7_RS10540	COG2860	membrane
BCS7_RS10555	COG0788	formyltetrahydrofolate deformylase activity
BCS7_RS10560	COG3012	SEC-C Motif Domain Protein
BCS7_RS10565	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCS7_RS10570	COG0745	RESPONSE REGULATOR receiver
BCS7_RS10575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCS7_RS10590	COG1435	thymidine kinase activity
BCS7_RS10595	COG1454	alcohol dehydrogenase
BCS7_RS10595	COG1012	belongs to the aldehyde dehydrogenase family
BCS7_RS10615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCS7_RS10620	COG0444	Belongs to the ABC transporter superfamily
BCS7_RS10635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCS7_RS10650	COG2350	Protein conserved in bacteria
BCS7_RS10660	COG1607	acyl-coa hydrolase
BCS7_RS10665	COG2917	probably involved in intracellular septation
BCS7_RS10675	COG3047	cAMP biosynthetic process
BCS7_RS10680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BCS7_RS10685	COG0159	tryptophan synthase activity
BCS7_RS10690	COG0133	tryptophan synthase activity
BCS7_RS10700	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCS7_RS10705	COG0512	Glutamine amidotransferase of anthranilate synthase
BCS7_RS10715	COG0613	PHP domain protein
BCS7_RS10720	COG0009	L-threonylcarbamoyladenylate synthase
BCS7_RS10725	COG1187	pseudouridine synthase activity
BCS7_RS10730	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BCS7_RS10735	COG1028	Short-chain dehydrogenase reductase Sdr
BCS7_RS10740	COG0616	signal peptide processing
BCS7_RS10765	COG3104	oligopeptide transport
BCS7_RS10770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCS7_RS10780	COG4659	FMN binding
BCS7_RS10785	COG4658	electron transport chain
BCS7_RS10790	COG4656	Part of a membrane complex involved in electron transport
BCS7_RS10795	COG2878	Part of a membrane complex involved in electron transport
BCS7_RS10800	COG4657	Part of a membrane complex involved in electron transport
BCS7_RS10810	COG2160	L-arabinose isomerase activity
BCS7_RS10815	COG1069	ribulokinase activity
BCS7_RS10820	COG1879	ABC-type sugar transport system periplasmic component
BCS7_RS10845	COG0385	Bile acid
BCS7_RS10850	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BCS7_RS10860	COG5339	Protein conserved in bacteria
BCS7_RS10865	COG1482	cell wall glycoprotein biosynthetic process
BCS7_RS10870	COG0114	fumarate hydratase activity
BCS7_RS10880	COG2814	Major facilitator Superfamily
BCS7_RS10885	COG0583	DNA-binding transcription factor activity
BCS7_RS10890	COG1940	carbohydrate kinase activity
BCS7_RS10895	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BCS7_RS10900	COG0477	Major facilitator Superfamily
BCS7_RS10920	COG4221	oxidoreductase activity
BCS7_RS10925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BCS7_RS10930	COG1215	transferase activity, transferring glycosyl groups
BCS7_RS10950	COG1942	4-Oxalocrotonate Tautomerase
BCS7_RS10955	COG0076	glutamate decarboxylase activity
BCS7_RS10960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCS7_RS10970	COG1649	PFAM Uncharacterised BCR, COG1649
BCS7_RS10975	COG4628	conserved protein (DUF2132)
BCS7_RS10980	COG1349	DNA-binding transcription factor activity
BCS7_RS10985	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCS7_RS10990	COG1028	Short-chain dehydrogenase reductase Sdr
BCS7_RS11040	COG0456	acetyltransferase
BCS7_RS11045	COG0738	Major facilitator superfamily
BCS7_RS11055	COG3783	Cytochrome b(562)
BCS7_RS11060	COG1764	response to oxidative stress
BCS7_RS11065	COG4305	rare lipoprotein A
BCS7_RS11090	COG1028	Short-chain dehydrogenase reductase Sdr
BCS7_RS11105	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BCS7_RS11120	COG0673	inositol 2-dehydrogenase activity
BCS7_RS11125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCS7_RS11130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCS7_RS11140	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BCS7_RS11145	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BCS7_RS11155	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BCS7_RS11160	COG2912	Transglutaminase-like superfamily
BCS7_RS11170	COG2890	protein-(glutamine-N5) methyltransferase activity
BCS7_RS11175	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BCS7_RS11180	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BCS7_RS11185	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BCS7_RS11190	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BCS7_RS11195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BCS7_RS11205	COG0193	aminoacyl-tRNA hydrolase activity
BCS7_RS11210	COG0012	GTP binding
BCS7_RS11225	COG4571	Outer membrane protease
BCS7_RS11265	COG0483	inositol monophosphate 1-phosphatase activity
BCS7_RS11275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCS7_RS11275	COG1263	PTS System
BCS7_RS11280	COG1609	Transcriptional regulator
BCS7_RS11285	COG2234	aminopeptidase activity
BCS7_RS11300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCS7_RS11305	COG1473	amidohydrolase
BCS7_RS11315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCS7_RS11325	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BCS7_RS11335	COG0765	amino acid transport
BCS7_RS11340	COG1126	abc transporter atp-binding protein
BCS7_RS11455	COG3210	domain, Protein
BCS7_RS11470	COG3210	domain, Protein
BCS7_RS11485	COG3210	domain, Protein
BCS7_RS11500	COG3210	domain, Protein
BCS7_RS11520	COG3210	domain, Protein
BCS7_RS11675	COG2200	EAL domain
BCS7_RS11740	COG4794	Type iii secretion
BCS7_RS11750	COG4792	protein secretion
BCS7_RS11765	COG1464	Belongs to the NlpA lipoprotein family
BCS7_RS11770	COG4948	Mandelate Racemase Muconate Lactonizing
BCS7_RS11775	COG2011	ABC-type metal ion transport system permease component
BCS7_RS11780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCS7_RS11795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCS7_RS11805	COG1028	Short-chain dehydrogenase reductase Sdr
BCS7_RS11815	COG1176	ABC-type spermidine putrescine transport system, permease component I
BCS7_RS11825	COG1012	belongs to the aldehyde dehydrogenase family
BCS7_RS11830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCS7_RS11840	COG3842	ATPase activity
BCS7_RS11845	COG1028	Short-chain dehydrogenase reductase Sdr
BCS7_RS11860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCS7_RS11870	COG2255	four-way junction helicase activity
BCS7_RS11875	COG2261	transglycosylase associated protein
BCS7_RS11935	COG1846	Transcriptional regulator
BCS7_RS11940	COG0697	spore germination
BCS7_RS11950	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BCS7_RS11955	COG1140	nitrate reductase beta subunit
BCS7_RS11960	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BCS7_RS11965	COG2223	nitrite transmembrane transporter activity
BCS7_RS11970	COG3850	Histidine kinase
BCS7_RS11975	COG2197	response regulator
BCS7_RS11990	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BCS7_RS12000	COG0387	Pfam Sodium calcium exchanger
BCS7_RS12015	COG1028	Short-chain dehydrogenase reductase Sdr
BCS7_RS12025	COG0745	RESPONSE REGULATOR receiver
BCS7_RS12040	COG3591	Belongs to the peptidase S1B family
BCS7_RS12045	COG5001	Diguanylate cyclase
BCS7_RS12045	COG3300	MHYT domain
BCS7_RS12055	COG1643	Atp-dependent helicase
BCS7_RS12060	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BCS7_RS12070	COG2911	Protein conserved in bacteria
BCS7_RS12075	COG0840	transmembrane signaling receptor activity
BCS7_RS12080	COG0840	transmembrane signaling receptor activity
BCS7_RS12085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCS7_RS12120	COG0037	tRNA processing
BCS7_RS12125	COG0598	Magnesium transport protein CorA
BCS7_RS12130	COG4166	transmembrane transport
BCS7_RS12135	COG2866	Carboxypeptidase
BCS7_RS12140	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BCS7_RS12170	COG3768	UPF0283 membrane protein
BCS7_RS12175	COG3106	COG3106 Predicted ATPase
BCS7_RS12180	COG2831	hemolysin activation secretion protein
BCS7_RS12215	COG1983	PspC domain protein
BCS7_RS12225	COG1842	Phage shock protein A
BCS7_RS12245	COG4166	transmembrane transport
BCS7_RS12255	COG4171	peptide transport system, permease
BCS7_RS12295	COG0583	DNA-binding transcription factor activity
BCS7_RS12300	COG0243	molybdopterin cofactor binding
BCS7_RS12310	COG4989	oxidoreductase activity
BCS7_RS12330	COG0023	Translation Initiation Factor
BCS7_RS12335	COG0284	orotidine-5'-phosphate decarboxylase activity
BCS7_RS12340	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BCS7_RS12355	COG0671	phosphoesterase, PA-phosphatase related
BCS7_RS12360	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCS7_RS12380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCS7_RS12385	COG1301	dicarboxylic acid transport
BCS7_RS12390	COG0625	glutathione transferase activity
BCS7_RS12395	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BCS7_RS12400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BCS7_RS12405	COG0259	pyridoxamine-phosphate oxidase activity
BCS7_RS12410	COG3895	Periplasmic Protein
BCS7_RS12415	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BCS7_RS12430	COG3313	Fe-S protein
BCS7_RS12435	COG0346	lactoylglutathione lyase activity
BCS7_RS12440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCS7_RS12445	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BCS7_RS12450	COG0791	NLP P60 protein
BCS7_RS12460	COG1609	Transcriptional regulator
BCS7_RS12470	COG0307	riboflavin synthase, alpha
BCS7_RS12475	COG0534	Mate efflux family protein
BCS7_RS12500	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BCS7_RS12505	COG1408	metallophosphoesterase
BCS7_RS12530	COG0604	alcohol dehydrogenase
BCS7_RS12540	COG0604	alcohol dehydrogenase
BCS7_RS12555	COG2197	response regulator
BCS7_RS12565	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCS7_RS12565	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCS7_RS12570	COG3062	negative regulation of establishment of protein localization
BCS7_RS12575	COG0243	molybdopterin cofactor binding
BCS7_RS12580	COG0437	4 iron, 4 sulfur cluster binding
BCS7_RS12590	COG3043	anaerobic respiration
BCS7_RS12600	COG4235	cytochrome complex assembly
BCS7_RS12600	COG3088	subunit of a heme lyase
BCS7_RS12605	COG4235	cytochrome complex assembly
BCS7_RS12605	COG3088	subunit of a heme lyase
BCS7_RS12610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCS7_RS12625	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCS7_RS12635	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCS7_RS12640	COG4133	protoheme IX ABC transporter activity
BCS7_RS12645	COG4235	cytochrome complex assembly
BCS7_RS12650	COG3088	subunit of a heme lyase
BCS7_RS12660	COG3301	Polysulphide reductase, NrfD
BCS7_RS12665	COG0437	4 iron, 4 sulfur cluster binding
BCS7_RS12670	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BCS7_RS12675	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BCS7_RS12685	COG2382	esterase
BCS7_RS12725	COG4238	major outer membrane lipoprotein
BCS7_RS12730	COG1388	LysM domain
BCS7_RS12730	COG1376	ErfK ybiS ycfS ynhG family protein
BCS7_RS12735	COG2166	iron-sulfur cluster assembly
BCS7_RS12740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCS7_RS12745	COG0719	Fe-S assembly protein
BCS7_RS12750	COG0396	ATPase activity
BCS7_RS12755	COG0719	Fe-S assembly protein
BCS7_RS12760	COG0316	Belongs to the HesB IscA family
BCS7_RS12770	COG2050	protein possibly involved in aromatic compounds catabolism
BCS7_RS12775	COG0247	lactate metabolic process
BCS7_RS12775	COG0277	FAD linked oxidase domain protein
BCS7_RS12780	COG0628	permease
BCS7_RS12790	COG1477	protein flavinylation
BCS7_RS12795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCS7_RS12795	COG0574	Belongs to the PEP-utilizing enzyme family
BCS7_RS12800	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BCS7_RS12805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCS7_RS12810	COG0366	Alpha amylase catalytic
BCS7_RS12815	COG2188	Transcriptional regulator
BCS7_RS12840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCS7_RS12845	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BCS7_RS12850	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BCS7_RS12855	COG0095	Lipoate-protein ligase
BCS7_RS12860	COG0791	NLP P60 protein
BCS7_RS12865	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BCS7_RS12870	COG0386	Belongs to the glutathione peroxidase family
BCS7_RS12875	COG4139	cobalamin transport
BCS7_RS12880	COG2226	methyltransferase
BCS7_RS12900	COG1940	carbohydrate kinase activity
BCS7_RS12910	COG1136	(ABC) transporter
BCS7_RS12915	COG4591	ABC-type transport system involved in lipoprotein release permease component
BCS7_RS12920	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCS7_RS12925	COG0443	Heat shock 70 kDa protein
BCS7_RS12930	COG1309	transcriptional regulator
BCS7_RS12940	COG2814	Major facilitator Superfamily
BCS7_RS12945	COG3134	Outer membrane lipoprotein
BCS7_RS12950	COG1252	NADH dehydrogenase
BCS7_RS12960	COG1472	Belongs to the glycosyl hydrolase 3 family
BCS7_RS12980	COG0537	adenosine 5'-monophosphoramidase activity
BCS7_RS12985	COG0477	Major facilitator Superfamily
BCS7_RS12995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCS7_RS12995	COG1263	PTS System
BCS7_RS13000	COG0084	hydrolase, TatD family'
BCS7_RS13005	COG0470	DNA polymerase III
BCS7_RS13010	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BCS7_RS13015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCS7_RS13020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCS7_RS13025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCS7_RS13030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCS7_RS13040	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCS7_RS13045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCS7_RS13050	COG0416	fatty acid biosynthetic process
BCS7_RS13055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BCS7_RS13060	COG1399	metal-binding, possibly nucleic acid-binding protein
BCS7_RS13065	COG0424	maF-like protein
BCS7_RS13070	COG0564	pseudouridine synthase activity
BCS7_RS13075	COG1530	ribonuclease E activity
BCS7_RS13075	COG1530	ribonuclease E activity
BCS7_RS13085	COG0418	dihydroorotase activity
BCS7_RS13105	COG3038	cytochrome b561
BCS7_RS13110	COG2353	YceI-like domain
BCS7_RS13115	COG1054	Belongs to the UPF0176 family
BCS7_RS13120	COG1902	pentaerythritol trinitrate reductase activity
BCS7_RS13125	COG1560	Kdo2-lipid A biosynthetic process
BCS7_RS13130	COG2943	transferase activity, transferring hexosyl groups
BCS7_RS13135	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BCS7_RS13150	COG0840	transmembrane signaling receptor activity
BCS7_RS13175	COG0589	response to stress
BCS7_RS13205	COG0670	Belongs to the BI1 family
BCS7_RS13210	COG2920	part of a sulfur-relay system
BCS7_RS13220	COG3785	DNA binding
BCS7_RS13225	COG1832	CoA-binding protein
BCS7_RS13235	COG1803	Methylglyoxal synthase
BCS7_RS13240	COG0210	DNA helicase
BCS7_RS13245	COG3304	Inner membrane component domain
BCS7_RS13250	COG1289	transmembrane transporter activity
BCS7_RS13255	COG3070	regulator of competence-specific genes
BCS7_RS13260	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
BCS7_RS13275	COG1067	ATP-dependent peptidase activity
BCS7_RS13280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCS7_RS13285	COG2979	Protein of unknown function (DUF533)
BCS7_RS13290	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BCS7_RS13300	COG1309	transcriptional regulator
BCS7_RS13305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCS7_RS13320	COG1702	phosphate starvation-inducible protein PhoH
BCS7_RS13330	COG1191	sigma factor activity
BCS7_RS13365	COG0500	methyltransferase
BCS7_RS13390	COG1677	Flagellar hook-basal body complex protein FliE
BCS7_RS13405	COG1317	bacterial-type flagellum organization
BCS7_RS13425	COG1580	Controls the rotational direction of flagella during chemotaxis
BCS7_RS13475	COG1706	bacterial-type flagellum-dependent cell motility
BCS7_RS13480	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BCS7_RS13490	COG4787	bacterial-type flagellum-dependent cell motility
BCS7_RS13495	COG1749	Flagellar hook protein flgE
BCS7_RS13500	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BCS7_RS13505	COG1558	bacterial-type flagellum-dependent cell motility
BCS7_RS13510	COG1815	bacterial-type flagellum-dependent cell motility
BCS7_RS13520	COG2747	anti-sigma28 factor FlgM
BCS7_RS13535	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCS7_RS13550	COG0745	RESPONSE REGULATOR receiver
BCS7_RS13555	COG2201	protein-glutamate methylesterase activity
BCS7_RS13560	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BCS7_RS13565	COG0840	transmembrane signaling receptor activity
BCS7_RS13570	COG0835	chemotaxis
BCS7_RS13575	COG2198	Histidine kinase
BCS7_RS13575	COG0643	Histidine kinase
BCS7_RS13600	COG0697	spore germination
BCS7_RS13605	COG0840	transmembrane signaling receptor activity
BCS7_RS13615	COG3706	GGDEF domain
BCS7_RS13625	COG3459	Glycosyltransferase 36 associated
BCS7_RS13630	COG1560	Kdo2-lipid A biosynthetic process
BCS7_RS13650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BCS7_RS13685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCS7_RS13700	COG0582	viral genome integration into host DNA
BCS7_RS13705	COG4974	Belongs to the 'phage' integrase family
BCS7_RS13775	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BCS7_RS13790	COG4695	Portal protein
BCS7_RS13830	COG3772	lysozyme
BCS7_RS13940	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCS7_RS13945	COG0322	excinuclease ABC activity
BCS7_RS13950	COG2197	response regulator
BCS7_RS13975	COG1113	amino acid transport
BCS7_RS14010	COG0745	RESPONSE REGULATOR receiver
BCS7_RS14040	COG2814	Major facilitator Superfamily
BCS7_RS14060	COG0519	Catalyzes the synthesis of GMP from XMP
BCS7_RS14110	COG1960	acyl-CoA dehydrogenase activity
BCS7_RS14125	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCS7_RS14135	COG2197	response regulator
BCS7_RS14170	COG1902	pentaerythritol trinitrate reductase activity
BCS7_RS14175	COG4221	oxidoreductase activity
BCS7_RS14180	COG1902	pentaerythritol trinitrate reductase activity
BCS7_RS14185	COG1309	transcriptional regulator
BCS7_RS14195	COG1309	transcriptional regulator
BCS7_RS14200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BCS7_RS14210	COG0702	epimerase
BCS7_RS14215	COG0702	epimerase
BCS7_RS14235	COG0398	Pfam SNARE associated Golgi protein
BCS7_RS14245	COG4221	oxidoreductase activity
BCS7_RS14245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCS7_RS14245	COG0604	alcohol dehydrogenase
BCS7_RS14245	COG3321	synthase
BCS7_RS14255	COG2814	Major facilitator Superfamily
BCS7_RS14295	COG4948	Mandelate Racemase Muconate Lactonizing
BCS7_RS14315	COG0745	RESPONSE REGULATOR receiver
BCS7_RS14320	COG5002	protein histidine kinase activity
BCS7_RS14320	COG5000	phosphorelay sensor kinase activity
BCS7_RS14345	COG1126	abc transporter atp-binding protein
BCS7_RS14360	COG0745	RESPONSE REGULATOR receiver
BCS7_RS14370	COG0640	Transcriptional regulator
BCS7_RS14380	COG0583	DNA-binding transcription factor activity
BCS7_RS14395	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BCS7_RS14410	COG0626	cystathionine gamma-synthase activity
BCS7_RS14415	COG1902	pentaerythritol trinitrate reductase activity
BCS7_RS14420	COG0640	Transcriptional regulator
BCS7_RS14425	COG1070	Carbohydrate kinase
BCS7_RS14430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCS7_RS14445	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCS7_RS14450	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCS7_RS14455	COG1129	ABC transporter
BCS7_RS14465	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BCS7_RS14470	COG4807	Protein conserved in bacteria
BCS7_RS14480	COG1648	precorrin-2 dehydrogenase activity
BCS7_RS14480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BCS7_RS14485	COG0243	molybdopterin cofactor binding
BCS7_RS14490	COG2146	nitrite reductase [NAD(P)H] activity
BCS7_RS14490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCS7_RS14495	COG1116	anion transmembrane transporter activity
BCS7_RS14505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCS7_RS14515	COG3707	response regulator
BCS7_RS14530	COG1271	oxidase subunit
BCS7_RS14535	COG1294	oxidase, subunit
BCS7_RS14540	COG4890	Cyd operon protein YbgT
BCS7_RS14545	COG2149	membrane
BCS7_RS14555	COG3058	Necessary for formate dehydrogenase activity
BCS7_RS14560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCS7_RS14565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCS7_RS14565	COG0519	Catalyzes the synthesis of GMP from XMP
BCS7_RS14595	COG0488	(ABC) transporter
BCS7_RS14610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCS7_RS14610	COG1263	PTS System
BCS7_RS14615	COG0366	Alpha amylase catalytic
BCS7_RS14620	COG4575	ribosome binding
BCS7_RS14625	COG1007	ATP synthesis coupled electron transport
BCS7_RS14630	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCS7_RS14635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCS7_RS14640	COG0713	ATP synthesis coupled electron transport
BCS7_RS14645	COG0839	Belongs to the complex I subunit 6 family
BCS7_RS14650	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCS7_RS14655	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BCS7_RS14670	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BCS7_RS14675	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCS7_RS14675	COG0649	NAD binding
BCS7_RS14680	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCS7_RS14695	COG0583	DNA-binding transcription factor activity
BCS7_RS14700	COG0436	Aminotransferase
BCS7_RS14705	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BCS7_RS14710	COG0471	metal ion transport
BCS7_RS14710	COG0490	domain, Protein
BCS7_RS14715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCS7_RS14720	COG3013	Belongs to the UPF0304 family
BCS7_RS14725	COG3092	negative regulation of chromosome organization
BCS7_RS14730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCS7_RS14735	COG0857	belongs to the CobB CobQ family
BCS7_RS14735	COG0280	phosphate acetyltransferase
BCS7_RS14745	COG3739	integral membrane protein
BCS7_RS14750	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BCS7_RS14760	COG0622	Phosphoesterase
BCS7_RS14765	COG0625	glutathione transferase activity
BCS7_RS14770	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCS7_RS14775	COG1090	epimerase
BCS7_RS14780	COG4598	ABC transporter
BCS7_RS14785	COG4160	amino acid transport
BCS7_RS14800	COG0163	prenyltransferase activity
BCS7_RS14805	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BCS7_RS14810	COG1286	toxin biosynthetic process
BCS7_RS14815	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BCS7_RS14820	COG0285	dihydrofolate synthase activity
BCS7_RS14825	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BCS7_RS14835	COG0586	Pfam SNARE associated Golgi protein
BCS7_RS14840	COG0101	tRNA pseudouridine synthase activity
BCS7_RS14845	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCS7_RS14850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCS7_RS14855	COG0697	spore germination
BCS7_RS14865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCS7_RS14870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCS7_RS14870	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BCS7_RS14880	COG3101	peptidyl-lysine hydroxylation
BCS7_RS14885	COG0730	response to heat
BCS7_RS14890	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BCS7_RS14895	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BCS7_RS14900	COG2890	protein-(glutamine-N5) methyltransferase activity
BCS7_RS14905	COG2840	Smr protein MutS2
BCS7_RS14910	COG2062	phosphohistidine phosphatase, SixA
BCS7_RS14940	COG1024	Enoyl-CoA hydratase
BCS7_RS14940	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCS7_RS14945	COG0183	Belongs to the thiolase family
BCS7_RS14955	COG1464	Belongs to the NlpA lipoprotein family
BCS7_RS14970	COG3691	Protein conserved in bacteria
BCS7_RS14975	COG2067	long-chain fatty acid transport protein
BCS7_RS14980	COG1028	Short-chain dehydrogenase reductase Sdr
BCS7_RS14990	COG0579	oxidoreductase
BCS7_RS15000	COG2116	formate transmembrane transporter activity
BCS7_RS15010	COG2801	Transposase and inactivated derivatives
BCS7_RS15115	COG1388	LysM domain
BCS7_RS15140	COG2885	chlorophyll binding
BCS7_RS15165	COG2801	Transposase and inactivated derivatives
BCS7_RS15195	COG0513	Belongs to the DEAD box helicase family
BCS7_RS15210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCS7_RS15215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCS7_RS15220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCS7_RS15300	COG3266	domain, Protein
BCS7_RS15310	COG0436	Aminotransferase
BCS7_RS15320	COG4948	Mandelate Racemase Muconate Lactonizing
BCS7_RS15330	COG1511	domain protein
BCS7_RS15330	COG3264	Mechanosensitive ion channel
BCS7_RS15345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCS7_RS15360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCS7_RS15365	COG1696	Membrane protein involved in D-alanine export
BCS7_RS15395	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCS7_RS15410	COG3842	ATPase activity
BCS7_RS15415	COG2076	Multidrug Resistance protein
BCS7_RS15420	COG2076	Multidrug Resistance protein
BCS7_RS15425	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BCS7_RS15430	COG0726	polysaccharide deacetylase
BCS7_RS15435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCS7_RS15435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCS7_RS15440	COG0463	Glycosyl transferase, family 2
BCS7_RS15445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BCS7_RS15450	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCS7_RS15460	COG5001	Diguanylate cyclase
BCS7_RS15460	COG3706	GGDEF domain
BCS7_RS15460	COG2203	Gaf domain
BCS7_RS15460	COG4251	negative regulation of phosphorylation
BCS7_RS15465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BCS7_RS15470	COG2501	S4 domain
BCS7_RS15475	COG0215	cysteine-tRNA ligase activity
BCS7_RS15485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCS7_RS15490	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCS7_RS15495	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BCS7_RS15500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BCS7_RS15505	COG0814	amino acid
BCS7_RS15520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BCS7_RS15525	COG0581	inorganic phosphate transmembrane transporter activity
BCS7_RS15530	COG0573	inorganic phosphate transmembrane transporter activity
BCS7_RS15535	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BCS7_RS15555	COG1764	response to oxidative stress
BCS7_RS15560	COG1846	Transcriptional regulator
BCS7_RS15565	COG2239	Acts as a magnesium transporter
BCS7_RS15580	COG1609	Transcriptional regulator
BCS7_RS15585	COG4580	involved in the transport of maltose and maltodextrins
BCS7_RS15595	COG3842	ATPase activity
BCS7_RS15600	COG2182	Extracellular solute-binding protein
BCS7_RS15605	COG1175	transmembrane transport
BCS7_RS15610	COG3833	ABC-type maltose transport systems, permease component
BCS7_RS15615	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BCS7_RS15635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCS7_RS15640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCS7_RS15645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCS7_RS15650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCS7_RS15655	COG0477	Major facilitator Superfamily
BCS7_RS15660	COG2205	protein histidine kinase activity
BCS7_RS15665	COG0745	RESPONSE REGULATOR receiver
BCS7_RS15680	COG0435	Glutathione S-transferase
BCS7_RS15690	COG1597	lipid kinase activity
BCS7_RS15695	COG3223	Belongs to the PsiE family
BCS7_RS15705	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BCS7_RS15715	COG1064	alcohol dehydrogenase
BCS7_RS15720	COG2203	Gaf domain
BCS7_RS15720	COG2199	diguanylate cyclase activity
BCS7_RS15725	COG1064	alcohol dehydrogenase
BCS7_RS15765	COG3423	Transcriptional regulator
BCS7_RS15780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCS7_RS15780	COG0519	Catalyzes the synthesis of GMP from XMP
BCS7_RS15790	COG1570	exodeoxyribonuclease VII activity
BCS7_RS15805	COG1645	bacterial-type flagellum-dependent swarming motility
BCS7_RS15815	COG1160	GTP binding
BCS7_RS15820	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCS7_RS15825	COG2976	Protein conserved in bacteria
BCS7_RS15830	COG0124	histidyl-tRNA synthetase
BCS7_RS15835	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BCS7_RS15840	COG1426	Protein conserved in bacteria
BCS7_RS15850	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BCS7_RS15855	COG0105	UTP biosynthetic process
BCS7_RS15860	COG2190	(PTS) system
BCS7_RS15860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCS7_RS15860	COG1263	PTS System
BCS7_RS15865	COG1486	melibiose metabolic process
BCS7_RS15870	COG2897	thiosulfate sulfurtransferase activity
BCS7_RS15885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCS7_RS15895	COG2975	iron-sulfur cluster assembly
BCS7_RS15900	COG0633	Ferredoxin
BCS7_RS15905	COG0443	Heat shock 70 kDa protein
BCS7_RS15910	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BCS7_RS15915	COG0316	Belongs to the HesB IscA family
BCS7_RS15920	COG0822	iron-sulfur transferase activity
BCS7_RS15925	COG1104	cysteine desulfurase activity
BCS7_RS15930	COG1959	2 iron, 2 sulfur cluster binding
BCS7_RS15935	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BCS7_RS15940	COG0483	inositol monophosphate 1-phosphatase activity
BCS7_RS15950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCS7_RS15955	COG1120	ATPase activity
BCS7_RS15965	COG0840	transmembrane signaling receptor activity
BCS7_RS15975	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BCS7_RS15980	COG3683	transport system, periplasmic component
BCS7_RS15985	COG2814	Major facilitator Superfamily
BCS7_RS15990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BCS7_RS15995	COG1017	nitric oxide dioxygenase activity
BCS7_RS15995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCS7_RS16005	COG4677	pectinesterase activity
BCS7_RS16015	COG0347	Belongs to the P(II) protein family
BCS7_RS16020	COG2204	response regulator
BCS7_RS16025	COG3170	Tfp pilus assembly protein FimV
BCS7_RS16030	COG2205	protein histidine kinase activity
BCS7_RS16035	COG0047	phosphoribosylformylglycinamidine synthase activity
BCS7_RS16035	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCS7_RS16040	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BCS7_RS16050	COG0560	Phosphoserine phosphatase
BCS7_RS16055	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BCS7_RS16065	COG3287	FIST C domain
BCS7_RS16065	COG2200	EAL domain
BCS7_RS16065	COG2199	diguanylate cyclase activity
BCS7_RS16090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCS7_RS16100	COG2200	EAL domain
BCS7_RS16105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCS7_RS16110	COG0736	holo-[acyl-carrier-protein] synthase activity
BCS7_RS16115	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BCS7_RS16120	COG1381	Involved in DNA repair and RecF pathway recombination
BCS7_RS16125	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BCS7_RS16130	COG0571	ribonuclease III activity
BCS7_RS16140	COG0481	GTPase activity
BCS7_RS16145	COG3086	response to oxidative stress
BCS7_RS16150	COG3026	antisigma factor binding
BCS7_RS16165	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BCS7_RS16170	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BCS7_RS16175	COG0513	Belongs to the DEAD box helicase family
BCS7_RS16180	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
BCS7_RS16185	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BCS7_RS16200	COG2819	hydrolase of the alpha beta superfamily
BCS7_RS16205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCS7_RS16235	COG1902	pentaerythritol trinitrate reductase activity
BCS7_RS16240	COG0667	Aldo Keto reductase
BCS7_RS16255	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BCS7_RS16260	COG4208	sulfate ABC transporter
BCS7_RS16270	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BCS7_RS16275	COG3835	regulator
BCS7_RS16285	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BCS7_RS16290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BCS7_RS16295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCS7_RS16305	COG0316	Belongs to the HesB IscA family
BCS7_RS16310	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCS7_RS16320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCS7_RS16330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCS7_RS16340	COG1120	ATPase activity
BCS7_RS16345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCS7_RS16350	COG1643	Atp-dependent helicase
BCS7_RS16355	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BCS7_RS16360	COG1489	DNA binding
BCS7_RS16370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCS7_RS16380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCS7_RS16385	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BCS7_RS16390	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BCS7_RS16395	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BCS7_RS16400	COG0842	Transport permease protein
BCS7_RS16405	COG1131	(ABC) transporter
BCS7_RS16410	COG0288	reversible hydration of carbon dioxide
BCS7_RS16425	COG3842	ATPase activity
BCS7_RS16440	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BCS7_RS16445	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BCS7_RS16450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BCS7_RS16455	COG1780	Probably involved in ribonucleotide reductase function
BCS7_RS16465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCS7_RS16480	COG0328	RNA-DNA hybrid ribonuclease activity
BCS7_RS16485	COG2226	methyltransferase
BCS7_RS16490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCS7_RS16540	COG0542	response to heat
BCS7_RS16550	COG0564	pseudouridine synthase activity
BCS7_RS16560	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCS7_RS16565	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BCS7_RS16570	COG1605	Chorismate mutase
BCS7_RS16570	COG0077	Prephenate dehydratase
BCS7_RS16575	COG0287	Prephenate dehydrogenase
BCS7_RS16575	COG1605	Chorismate mutase
BCS7_RS16580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCS7_RS16585	COG3279	Response regulator of the LytR AlgR family
BCS7_RS16595	COG2264	protein methyltransferase activity
BCS7_RS16605	COG0335	large ribosomal subunit rRNA binding
BCS7_RS16610	COG0336	Belongs to the RNA methyltransferase TrmD family
BCS7_RS16615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BCS7_RS16620	COG0228	four-way junction DNA binding
BCS7_RS16625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCS7_RS16630	COG4137	Cytochrome C assembly protein
BCS7_RS16635	COG1854	S-ribosylhomocysteine lyase activity
BCS7_RS16640	COG2918	glutathione biosynthetic process
BCS7_RS16645	COG1238	metal cluster binding
BCS7_RS16650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCS7_RS16680	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BCS7_RS16685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCS7_RS16690	COG2137	regulation of response to DNA damage stimulus
BCS7_RS16695	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BCS7_RS16700	COG1546	Belongs to the CinA family
BCS7_RS16720	COG3706	GGDEF domain
BCS7_RS16730	COG0583	DNA-binding transcription factor activity
BCS7_RS16735	COG2999	glutathione oxidoreductase activity
BCS7_RS16795	COG3209	COG3209 Rhs family protein
BCS7_RS16865	COG3501	Rhs element vgr protein
BCS7_RS16925	COG4221	oxidoreductase activity
BCS7_RS16930	COG1309	transcriptional regulator
BCS7_RS17030	COG1070	Carbohydrate kinase
BCS7_RS17040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCS7_RS17045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCS7_RS17050	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCS7_RS17105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BCS7_RS17110	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BCS7_RS17120	COG1073	alpha beta
BCS7_RS17125	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BCS7_RS17130	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCS7_RS17135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCS7_RS17145	COG2226	methyltransferase
BCS7_RS17150	COG3034	peptidoglycan biosynthetic process
BCS7_RS17155	COG0121	glutamine amidotransferase
BCS7_RS17160	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BCS7_RS17165	COG1960	acyl-CoA dehydrogenase activity
BCS7_RS17175	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BCS7_RS17180	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BCS7_RS17235	COG3501	Rhs element vgr protein
BCS7_RS17240	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BCS7_RS17245	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BCS7_RS17250	COG0235	Class ii aldolase
BCS7_RS17255	COG0436	Aminotransferase
BCS7_RS17265	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCS7_RS17275	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BCS7_RS17285	COG0765	amino acid transport
BCS7_RS17335	COG4175	Glycine betaine
BCS7_RS17340	COG4176	ABC-type proline glycine betaine transport system permease component
BCS7_RS17345	COG2113	Glycine betaine
BCS7_RS17350	COG0596	Alpha beta hydrolase
BCS7_RS17360	COG2706	6-phosphogluconolactonase activity
BCS7_RS17365	COG2814	Major facilitator Superfamily
BCS7_RS17370	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BCS7_RS17380	COG1846	Transcriptional regulator
BCS7_RS17385	COG1566	PFAM secretion protein HlyD family protein
BCS7_RS17390	COG2814	Major facilitator Superfamily
BCS7_RS17395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCS7_RS17405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCS7_RS17410	COG3118	belongs to the thioredoxin family
BCS7_RS17415	COG3148	PFAM DTW domain containing protein
BCS7_RS17420	COG0045	succinate-CoA ligase (ADP-forming) activity
BCS7_RS17420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCS7_RS17420	COG1042	CoA-binding domain protein
BCS7_RS17425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCS7_RS17430	COG0477	Major facilitator Superfamily
BCS7_RS17465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BCS7_RS17470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCS7_RS17475	COG2011	ABC-type metal ion transport system permease component
BCS7_RS17480	COG1464	Belongs to the NlpA lipoprotein family
BCS7_RS17490	COG1720	tRNA m6t6A37 methyltransferase activity
BCS7_RS17495	COG0442	prolyl-tRNA aminoacylation
BCS7_RS17510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BCS7_RS17515	COG0585	pseudouridine synthase activity
BCS7_RS17520	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BCS7_RS17525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BCS7_RS17530	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BCS7_RS17540	COG0765	amino acid transport
BCS7_RS17545	COG1126	abc transporter atp-binding protein
BCS7_RS17555	COG0529	Catalyzes the synthesis of activated sulfate
BCS7_RS17560	COG2895	sulfate adenylyltransferase (ATP) activity
BCS7_RS17565	COG0175	sulfate reduction
BCS7_RS17570	COG1648	precorrin-2 dehydrogenase activity
BCS7_RS17570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BCS7_RS17580	COG2207	Transcriptional regulator
BCS7_RS17585	COG1064	alcohol dehydrogenase
BCS7_RS17595	COG0175	sulfate reduction
BCS7_RS17600	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCS7_RS17625	COG0720	synthase
BCS7_RS17630	COG0602	queuosine metabolic process
BCS7_RS17640	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BCS7_RS17650	COG0583	DNA-binding transcription factor activity
BCS7_RS17670	COG0148	phosphopyruvate hydratase activity
BCS7_RS17675	COG0504	CTP synthase activity
BCS7_RS17680	COG3956	TIGRFAM MazG family protein
BCS7_RS17685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCS7_RS17690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCS7_RS17700	COG1929	Belongs to the glycerate kinase type-1 family
BCS7_RS17705	COG2084	Dehydrogenase
BCS7_RS17715	COG4948	Mandelate Racemase Muconate Lactonizing
BCS7_RS17720	COG4948	Mandelate Racemase Muconate Lactonizing
BCS7_RS17725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BCS7_RS17740	COG2271	Major facilitator Superfamily
BCS7_RS17750	COG0840	transmembrane signaling receptor activity
BCS7_RS17765	COG3530	Putative quorum-sensing-regulated virulence factor
BCS7_RS17775	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BCS7_RS17775	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BCS7_RS17785	COG3025	triphosphatase activity
BCS7_RS17790	COG4991	sh3 domain protein
BCS7_RS17795	COG0617	tRNA 3'-terminal CCA addition
BCS7_RS17800	COG1968	undecaprenyl-diphosphatase activity
BCS7_RS17805	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCS7_RS17810	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BCS7_RS17815	COG0840	transmembrane signaling receptor activity
BCS7_RS17820	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BCS7_RS17825	COG2105	PFAM AIG2 family protein
BCS7_RS17830	COG2911	Protein conserved in bacteria
BCS7_RS17835	COG0729	surface antigen
BCS7_RS17840	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCS7_RS17845	COG1253	flavin adenine dinucleotide binding
BCS7_RS17855	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BCS7_RS17860	COG1218	3'(2'),5'-bisphosphate nucleotidase
BCS7_RS17865	COG0737	Belongs to the 5'-nucleotidase family
BCS7_RS17875	COG3961	Belongs to the TPP enzyme family
BCS7_RS17880	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BCS7_RS17885	COG0545	Peptidyl-prolyl cis-trans isomerase
BCS7_RS17890	COG3061	Opacity-associated protein A
BCS7_RS17900	COG0359	binds to the 23S rRNA
BCS7_RS17905	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BCS7_RS17910	COG2965	DNA replication, synthesis of RNA primer
BCS7_RS17915	COG0360	Binds together with S18 to 16S ribosomal RNA
BCS7_RS17920	COG1073	alpha beta
BCS7_RS17925	COG0840	transmembrane signaling receptor activity
BCS7_RS17930	COG1690	Belongs to the RtcB family
BCS7_RS17935	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCS7_RS17955	COG3766	membrane
BCS7_RS17960	COG0840	transmembrane signaling receptor activity
BCS7_RS17965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCS7_RS17970	COG0557	exoribonuclease II activity
BCS7_RS17975	COG1959	2 iron, 2 sulfur cluster binding
BCS7_RS17980	COG0840	transmembrane signaling receptor activity
BCS7_RS17990	COG2805	Type II/IV secretion system protein
BCS7_RS17995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCS7_RS18000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCS7_RS18005	COG0762	integral membrane protein
BCS7_RS18010	COG1872	DUF167
BCS7_RS18015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BCS7_RS18020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCS7_RS18025	COG0840	transmembrane signaling receptor activity
BCS7_RS18035	COG2153	protein acetylation
BCS7_RS18040	COG0477	Major facilitator Superfamily
BCS7_RS18045	COG0318	PFAM AMP-dependent synthetase and ligase
BCS7_RS18045	COG0204	Acyl-transferase
BCS7_RS18055	COG2186	Transcriptional regulator
BCS7_RS18060	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCS7_RS18065	COG2723	6-phospho-beta-galactosidase activity
BCS7_RS18070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCS7_RS18075	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCS7_RS18080	COG1609	Transcriptional regulator
BCS7_RS18085	COG1396	sequence-specific DNA binding
BCS7_RS18100	COG0583	DNA-binding transcription factor activity
BCS7_RS18105	COG0583	DNA-binding transcription factor activity
BCS7_RS18130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCS7_RS18150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCS7_RS18170	COG1522	sequence-specific DNA binding
BCS7_RS18180	COG1448	Aminotransferase
BCS7_RS18185	COG1451	nucleotide metabolic process
BCS7_RS18220	COG0432	Pfam Uncharacterised protein family UPF0047
BCS7_RS18230	COG0629	single-stranded DNA binding
BCS7_RS18265	COG2211	Major facilitator Superfamily
BCS7_RS18290	COG0395	ABC-type sugar transport system, permease component
BCS7_RS18295	COG1175	transmembrane transport
BCS7_RS18300	COG3842	ATPase activity
BCS7_RS18305	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BCS7_RS18330	COG2971	BadF BadG BcrA BcrD
BCS7_RS18340	COG1121	(ABC) transporter
BCS7_RS18345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCS7_RS18350	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCS7_RS18355	COG1349	DNA-binding transcription factor activity
BCS7_RS18360	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BCS7_RS18365	COG3395	kinase activity
BCS7_RS18370	COG1454	alcohol dehydrogenase
BCS7_RS18375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCS7_RS18390	COG2731	YhcH YjgK YiaL family protein
BCS7_RS18400	COG1028	Short-chain dehydrogenase reductase Sdr
BCS7_RS18405	COG1882	Formate acetyltransferase
BCS7_RS18410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCS7_RS18435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCS7_RS18450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCS7_RS18455	COG3112	Uncharacterised protein family (UPF0231)
BCS7_RS18475	COG0640	Transcriptional regulator
BCS7_RS18485	COG2207	Transcriptional regulator
BCS7_RS18490	COG2079	MmgE PrpD family protein
BCS7_RS18500	COG1073	alpha beta
BCS7_RS18505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCS7_RS18510	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCS7_RS18515	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BCS7_RS18525	COG1113	amino acid transport
BCS7_RS18535	COG3023	N-Acetylmuramoyl-L-alanine amidase
BCS7_RS18540	COG3248	Nucleoside-binding outer membrane protein
BCS7_RS18545	COG0157	Belongs to the NadC ModD family
BCS7_RS18550	COG4969	Belongs to the N-Me-Phe pilin family
BCS7_RS18555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCS7_RS18560	COG1459	type II secretion system
BCS7_RS18565	COG0516	GMP reductase activity
BCS7_RS18570	COG0237	dephospho-CoA kinase activity
BCS7_RS18575	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BCS7_RS18580	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BCS7_RS18585	COG0494	nUDIX hydrolase
BCS7_RS18605	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BCS7_RS18610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCS7_RS18615	COG0849	cell division
BCS7_RS18620	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BCS7_RS18625	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCS7_RS18630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCS7_RS18635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCS7_RS18640	COG0772	Belongs to the SEDS family
BCS7_RS18645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BCS7_RS18650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCS7_RS18655	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCS7_RS18660	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BCS7_RS18665	COG0768	penicillin binding
BCS7_RS18670	COG3116	cell division
BCS7_RS18675	COG0275	rRNA processing
BCS7_RS18680	COG2001	Belongs to the MraZ family
BCS7_RS18690	COG1609	Transcriptional regulator
BCS7_RS18700	COG0028	Belongs to the TPP enzyme family
BCS7_RS18710	COG1022	Amp-dependent synthetase and ligase
BCS7_RS18715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCS7_RS18720	COG0473	3-isopropylmalate dehydrogenase activity
BCS7_RS18725	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BCS7_RS18730	COG0066	3-isopropylmalate dehydratase activity
BCS7_RS18750	COG0840	transmembrane signaling receptor activity
BCS7_RS18770	COG4533	DNA binding
BCS7_RS18775	COG4143	(ABC) transporter
BCS7_RS18785	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BCS7_RS18790	COG3507	Belongs to the glycosyl hydrolase 43 family
BCS7_RS18805	COG0028	Belongs to the TPP enzyme family
BCS7_RS18810	COG0440	acetolactate synthase activity
BCS7_RS18815	COG0586	Pfam SNARE associated Golgi protein
BCS7_RS18820	COG3706	GGDEF domain
BCS7_RS18825	COG0417	DNA replication proofreading
BCS7_RS18830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCS7_RS18835	COG0564	pseudouridine synthase activity
BCS7_RS18840	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BCS7_RS18845	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BCS7_RS18850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCS7_RS18860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BCS7_RS18865	COG2967	ApaG domain
BCS7_RS18890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BCS7_RS18895	COG3610	response to peptide
BCS7_RS18900	COG2966	Psort location CytoplasmicMembrane, score
BCS7_RS18920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BCS7_RS18925	COG0505	Belongs to the CarA family
BCS7_RS18930	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BCS7_RS18940	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BCS7_RS18945	COG1047	Peptidyl-prolyl cis-trans
BCS7_RS18955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BCS7_RS18960	COG0196	riboflavin kinase activity
BCS7_RS18970	COG0268	Binds directly to 16S ribosomal RNA
BCS7_RS18975	COG0583	DNA-binding transcription factor activity
BCS7_RS18980	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BCS7_RS18985	COG0484	heat shock protein binding
BCS7_RS18990	COG0443	Heat shock 70 kDa protein
BCS7_RS18995	COG1584	GPR1 FUN34 yaaH family protein
BCS7_RS19005	COG0521	Mo-molybdopterin cofactor biosynthetic process
BCS7_RS19015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCS7_RS19020	COG3022	response to hydroperoxide
BCS7_RS19030	COG0083	homoserine kinase activity
BCS7_RS19045	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BCS7_RS19050	COG0745	RESPONSE REGULATOR receiver
BCS7_RS19055	COG3045	CreA protein
BCS7_RS19060	COG2207	Transcriptional regulator
BCS7_RS19060	COG3708	Transcriptional regulator
BCS7_RS19070	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BCS7_RS19075	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
BCS7_RS19085	COG0488	(ABC) transporter
BCS7_RS19095	COG0840	transmembrane signaling receptor activity
BCS7_RS19100	COG0583	DNA-binding transcription factor activity
BCS7_RS19105	COG0604	alcohol dehydrogenase
BCS7_RS19110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCS7_RS19115	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BCS7_RS19120	COG0583	DNA-binding transcription factor activity
BCS7_RS19130	COG1279	arginine transmembrane transporter activity
BCS7_RS19135	COG0668	transmembrane transport
BCS7_RS19140	COG0191	fructose-bisphosphate aldolase activity
BCS7_RS19145	COG0126	phosphoglycerate kinase activity
BCS7_RS19150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCS7_RS19155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCS7_RS19165	COG0501	Belongs to the peptidase M48B family
BCS7_RS19175	COG1166	arginine decarboxylase activity
BCS7_RS19180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BCS7_RS19185	COG3091	SprT-like family
BCS7_RS19190	COG2356	endonuclease I
BCS7_RS19195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BCS7_RS19200	COG0189	ligase activity
BCS7_RS19205	COG1678	Uncharacterized ACR, COG1678
BCS7_RS19210	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BCS7_RS19215	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BCS7_RS19220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCS7_RS19225	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BCS7_RS19230	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BCS7_RS19235	COG0330	HflC and HflK could
BCS7_RS19240	COG0330	HflC and HflK could
BCS7_RS19245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCS7_RS19250	COG1923	regulation of RNA biosynthetic process
BCS7_RS19255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCS7_RS19260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BCS7_RS19265	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCS7_RS19270	COG0802	atpase or kinase
BCS7_RS19275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BCS7_RS19275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BCS7_RS19280	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCS7_RS19310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCS7_RS19320	COG1064	alcohol dehydrogenase
BCS7_RS19340	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BCS7_RS19345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCS7_RS19360	COG1011	Hydrolase
BCS7_RS19385	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BCS7_RS19390	COG1162	GTPase activity
BCS7_RS19395	COG0688	phosphatidylethanolamine metabolic process
BCS7_RS19400	COG1511	domain protein
BCS7_RS19400	COG3264	Mechanosensitive ion channel
BCS7_RS19405	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BCS7_RS19410	COG1053	succinate dehydrogenase
BCS7_RS19415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCS7_RS19420	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BCS7_RS19425	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BCS7_RS19435	COG3040	lipid binding
BCS7_RS19460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BCS7_RS19465	COG1509	lysine 2,3-aminomutase activity
BCS7_RS19475	COG0166	Belongs to the GPI family
BCS7_RS19480	COG0527	aspartate kinase activity
BCS7_RS19490	COG0471	metal ion transport
BCS7_RS19505	COG1410	methionine synthase
BCS7_RS19505	COG0646	methionine synthase
BCS7_RS19515	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BCS7_RS19525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BCS7_RS19530	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BCS7_RS19560	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCS7_RS19570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BCS7_RS19575	COG0009	L-threonylcarbamoyladenylate synthase
BCS7_RS19580	COG0551	DNA topoisomerase type I activity
BCS7_RS19585	COG2922	Belongs to the Smg family
BCS7_RS19590	COG0758	DNA mediated transformation
BCS7_RS19595	COG0242	peptide deformylase activity
BCS7_RS19600	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCS7_RS19605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BCS7_RS19605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCS7_RS19610	COG0569	domain protein
BCS7_RS19615	COG1970	mechanosensitive ion channel activity
BCS7_RS19620	COG3036	rescue of stalled ribosome
BCS7_RS19625	COG0203	ribosomal protein L17
BCS7_RS19630	COG0202	RNA polymerase activity
BCS7_RS19635	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BCS7_RS19645	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BCS7_RS19650	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BCS7_RS19655	COG0201	protein transport
BCS7_RS19660	COG0200	Binds to the 23S rRNA
BCS7_RS19665	COG1841	ribosomal large subunit assembly
BCS7_RS19670	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BCS7_RS19675	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BCS7_RS19680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BCS7_RS19685	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BCS7_RS19690	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BCS7_RS19695	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BCS7_RS19700	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BCS7_RS19710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BCS7_RS19715	COG0255	Belongs to the universal ribosomal protein uL29 family
BCS7_RS19720	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BCS7_RS19725	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BCS7_RS19730	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BCS7_RS19735	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BCS7_RS19740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BCS7_RS19750	COG0088	Forms part of the polypeptide exit tunnel
BCS7_RS19755	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BCS7_RS19760	COG0051	transcription antitermination factor activity, RNA binding
BCS7_RS19780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BCS7_RS19785	COG0049	tRNA binding
BCS7_RS19790	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BCS7_RS19795	COG2168	tRNA wobble position uridine thiolation
BCS7_RS19800	COG2923	Belongs to the DsrF TusC family
BCS7_RS19805	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BCS7_RS19810	COG2964	Protein conserved in bacteria
BCS7_RS19820	COG0745	RESPONSE REGULATOR receiver
BCS7_RS19825	COG0642	Histidine kinase
BCS7_RS19830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BCS7_RS19845	COG0545	Peptidyl-prolyl cis-trans isomerase
BCS7_RS19850	COG2900	Belongs to the SlyX family
BCS7_RS19855	COG1047	Peptidyl-prolyl cis-trans
BCS7_RS19860	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BCS7_RS19865	COG0475	glutathione-regulated potassium exporter activity
BCS7_RS19865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCS7_RS19870	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCS7_RS19875	COG0488	(ABC) transporter
BCS7_RS19880	COG3853	Toxic anion resistance protein (TelA)
BCS7_RS19895	COG0429	hydrolase of the alpha beta-hydrolase fold
BCS7_RS19900	COG3089	Belongs to the UPF0270 family
BCS7_RS19905	COG3954	Phosphoribulokinase
BCS7_RS19910	COG1765	OsmC-like protein
BCS7_RS19960	COG0582	viral genome integration into host DNA
BCS7_RS19985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCS7_RS19990	COG4608	Belongs to the ABC transporter superfamily
BCS7_RS19995	COG0444	Belongs to the ABC transporter superfamily
BCS7_RS20000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCS7_RS20005	COG0601	transmembrane transport
BCS7_RS20010	COG0747	negative chemotaxis
BCS7_RS20015	COG4948	Mandelate Racemase Muconate Lactonizing
BCS7_RS20020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCS7_RS20030	COG1648	precorrin-2 dehydrogenase activity
BCS7_RS20030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BCS7_RS20055	COG1473	amidohydrolase
BCS7_RS20060	COG0180	Tryptophanyl-tRNA synthetase
BCS7_RS20065	COG0546	phosphoglycolate phosphatase activity
BCS7_RS20070	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCS7_RS20085	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BCS7_RS20090	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BCS7_RS20095	COG4796	Type ii and iii secretion system protein
BCS7_RS20120	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BCS7_RS20125	COG0494	nUDIX hydrolase
BCS7_RS20140	COG1011	Hydrolase
BCS7_RS20145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BCS7_RS20150	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BCS7_RS20155	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BCS7_RS20180	COG2814	Major facilitator Superfamily
BCS7_RS20185	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BCS7_RS20190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCS7_RS20195	COG0019	diaminopimelate decarboxylase activity
BCS7_RS20200	COG4774	siderophore transport
BCS7_RS20205	COG4264	IucA IucC family
BCS7_RS20215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCS7_RS20225	COG0840	transmembrane signaling receptor activity
BCS7_RS20235	COG2183	response to ionizing radiation
BCS7_RS20240	COG1414	Transcriptional regulator
BCS7_RS20270	COG1785	Belongs to the alkaline phosphatase family
BCS7_RS20275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCS7_RS20290	COG3157	Type VI secretion system effector, Hcp
BCS7_RS20295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCS7_RS20300	COG2267	carboxylic ester hydrolase activity
BCS7_RS20305	COG1040	competence protein
BCS7_RS20310	COG0316	Belongs to the HesB IscA family
BCS7_RS20310	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BCS7_RS20315	COG1640	4-alpha-glucanotransferase
BCS7_RS20325	COG1349	DNA-binding transcription factor activity
BCS7_RS20330	COG0705	Rhomboid family
BCS7_RS20335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCS7_RS20385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BCS7_RS20390	COG3501	Rhs element vgr protein
BCS7_RS20425	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BCS7_RS20430	COG3275	phosphorelay sensor kinase activity
BCS7_RS20440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCS7_RS20445	COG2095	MarC family integral membrane protein
BCS7_RS20450	COG2610	gluconate transmembrane transporter activity
BCS7_RS20455	COG3265	gluconokinase activity
BCS7_RS20460	COG1609	Transcriptional regulator
BCS7_RS20465	COG1741	Belongs to the pirin family
BCS7_RS20470	COG0247	lactate metabolic process
BCS7_RS20475	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BCS7_RS20480	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BCS7_RS20490	COG2271	Major facilitator Superfamily
BCS7_RS20495	COG0584	glycerophosphoryl diester phosphodiesterase
BCS7_RS20500	COG0561	phosphatase activity
BCS7_RS20505	COG2267	carboxylic ester hydrolase activity
BCS7_RS20510	COG1280	lysine exporter protein (LysE YggA)
BCS7_RS20515	COG1280	lysine exporter protein (LysE YggA)
BCS7_RS20520	COG0514	ATP-dependent DNA helicase (RecQ)
BCS7_RS20530	COG2050	protein possibly involved in aromatic compounds catabolism
BCS7_RS20540	COG3180	Ammonia monooxygenase
BCS7_RS20545	COG0598	Magnesium transport protein CorA
BCS7_RS20550	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BCS7_RS20555	COG0210	DNA helicase
BCS7_RS20565	COG1011	Hydrolase
BCS7_RS20580	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BCS7_RS20590	COG1965	Belongs to the frataxin family
BCS7_RS20595	COG2814	Major facilitator Superfamily
BCS7_RS20605	COG0181	hydroxymethylbilane synthase activity
BCS7_RS20610	COG1587	Uroporphyrinogen-III synthase
BCS7_RS20615	COG2959	enzyme of heme biosynthesis
BCS7_RS20620	COG3071	HemY protein
BCS7_RS20625	COG1802	Transcriptional regulator
BCS7_RS20645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCS7_RS20650	COG4597	amino acid ABC transporter
BCS7_RS20655	COG0765	amino acid transport
BCS7_RS20660	COG1126	abc transporter atp-binding protein
BCS7_RS20665	COG1473	amidohydrolase
BCS7_RS20670	COG1126	abc transporter atp-binding protein
BCS7_RS20675	COG0765	amino acid transport
BCS7_RS20680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCS7_RS20685	COG0456	acetyltransferase
BCS7_RS20690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BCS7_RS20720	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BCS7_RS20730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BCS7_RS20735	COG2244	polysaccharide biosynthetic process
BCS7_RS20740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BCS7_RS20745	COG0456	acetyltransferase
BCS7_RS20750	COG1088	dTDP-glucose 4,6-dehydratase activity
BCS7_RS20755	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BCS7_RS20760	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BCS7_RS20770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCS7_RS20775	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BCS7_RS20780	COG3118	belongs to the thioredoxin family
BCS7_RS20785	COG0513	Belongs to the DEAD box helicase family
BCS7_RS20790	COG0248	Ppx GppA phosphatase
BCS7_RS20800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCS7_RS20815	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BCS7_RS20820	COG0583	DNA-binding transcription factor activity
BCS7_RS20865	COG0129	dihydroxy-acid dehydratase activity
BCS7_RS20875	COG3978	acetolactate synthase activity
BCS7_RS20895	COG3085	chromosome segregation
BCS7_RS20900	COG0583	DNA-binding transcription factor activity
BCS7_RS20905	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCS7_RS20910	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCS7_RS20915	COG1129	ABC transporter
BCS7_RS20920	COG1879	ABC-type sugar transport system periplasmic component
BCS7_RS20960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BCS7_RS20965	COG4206	TonB-dependent receptor
BCS7_RS20970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCS7_RS20980	COG1309	transcriptional regulator
BCS7_RS20985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCS7_RS21000	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BCS7_RS21010	COG0395	ABC-type sugar transport system, permease component
BCS7_RS21025	COG3842	ATPase activity
BCS7_RS21030	COG0527	aspartate kinase activity
BCS7_RS21030	COG0460	homoserine dehydrogenase
BCS7_RS21035	COG0626	cystathionine gamma-synthase activity
BCS7_RS21040	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
BCS7_RS21045	COG1120	ATPase activity
BCS7_RS21065	COG1598	PFAM Uncharacterised protein family UPF0150
BCS7_RS21070	COG0254	rRNA binding
BCS7_RS21075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCS7_RS21080	COG1609	Transcriptional regulator
BCS7_RS21085	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BCS7_RS21090	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BCS7_RS21095	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BCS7_RS21100	COG1575	Belongs to the MenA family. Type 1 subfamily
BCS7_RS21105	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BCS7_RS21110	COG3074	FtsZ-dependent cytokinesis
BCS7_RS21120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BCS7_RS21130	COG1494	fructose-1,6-bisphosphatase
BCS7_RS21140	COG3152	Membrane
BCS7_RS21150	COG0149	triose-phosphate isomerase activity
BCS7_RS21155	COG2957	Belongs to the agmatine deiminase family
BCS7_RS21160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCS7_RS21165	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCS7_RS21200	COG3188	usher protein
BCS7_RS21220	COG2205	protein histidine kinase activity
BCS7_RS21225	COG0745	RESPONSE REGULATOR receiver
BCS7_RS21230	COG3678	ATP-independent chaperone mediated protein folding
BCS7_RS21245	COG3831	ATPase activity
BCS7_RS21250	COG0714	Associated with various cellular activities
BCS7_RS21255	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BCS7_RS21260	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BCS7_RS21270	COG2814	Major facilitator Superfamily
BCS7_RS21275	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BCS7_RS21280	COG0205	6-phosphofructokinase activity
BCS7_RS21285	COG0583	DNA-binding transcription factor activity
BCS7_RS21325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCS7_RS21330	COG1116	anion transmembrane transporter activity
BCS7_RS21350	COG0584	glycerophosphoryl diester phosphodiesterase
BCS7_RS21355	COG3842	ATPase activity
BCS7_RS21360	COG0395	ABC-type sugar transport system, permease component
BCS7_RS21365	COG1175	transmembrane transport
BCS7_RS21370	COG1653	transport
BCS7_RS21390	COG1349	DNA-binding transcription factor activity
BCS7_RS21395	COG2084	Dehydrogenase
BCS7_RS21400	COG3395	kinase activity
BCS7_RS21405	COG0235	Class ii aldolase
BCS7_RS21410	COG3622	Belongs to the hyi family
BCS7_RS21415	COG2610	gluconate transmembrane transporter activity
BCS7_RS21420	COG0840	transmembrane signaling receptor activity
BCS7_RS21425	COG0840	transmembrane signaling receptor activity
BCS7_RS21430	COG0840	transmembrane signaling receptor activity
BCS7_RS21435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCS7_RS21440	COG0410	ABC transporter
BCS7_RS21445	COG0411	ABC transporter
BCS7_RS21455	COG0559	Belongs to the binding-protein-dependent transport system permease family
BCS7_RS21460	COG0683	leucine binding
BCS7_RS21475	COG2177	Part of the ABC transporter FtsEX involved in
BCS7_RS21480	COG2884	Cell division ATP-binding protein ftsE
BCS7_RS21485	COG0552	protein localization to endoplasmic reticulum
BCS7_RS21490	COG0742	ribosomal rna small subunit methyltransferase
BCS7_RS21495	COG3776	membrane
BCS7_RS21505	COG3714	YhhN family
BCS7_RS21520	COG0425	Belongs to the sulfur carrier protein TusA family
BCS7_RS21525	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BCS7_RS21540	COG1295	ribonuclease BN
BCS7_RS21545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCS7_RS21550	COG0612	Peptidase, M16
BCS7_RS21555	COG1301	dicarboxylic acid transport
BCS7_RS21565	COG2194	sulfuric ester hydrolase activity
BCS7_RS21590	COG1215	transferase activity, transferring glycosyl groups
BCS7_RS21600	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BCS7_RS21610	COG2831	hemolysin activation secretion protein
BCS7_RS21675	COG3977	Valine--pyruvate aminotransferase
BCS7_RS21685	COG3501	Rhs element vgr protein
BCS7_RS21720	COG3209	COG3209 Rhs family protein
BCS7_RS21720	COG4104	PAAR repeat-containing protein
BCS7_RS21740	COG3209	COG3209 Rhs family protein
BCS7_RS21740	COG4104	PAAR repeat-containing protein
BCS7_RS21745	COG4608	Belongs to the ABC transporter superfamily
BCS7_RS21750	COG0444	Belongs to the ABC transporter superfamily
BCS7_RS21755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCS7_RS21760	COG0601	transmembrane transport
BCS7_RS21765	COG0747	negative chemotaxis
BCS7_RS21775	COG3493	citrate carrier protein
BCS7_RS21800	COG4565	transcriptional regulatory protein
BCS7_RS21805	COG3290	protein histidine kinase activity
BCS7_RS21810	COG0471	metal ion transport
BCS7_RS21815	COG2985	domain, Protein
BCS7_RS21815	COG0569	domain protein
BCS7_RS21825	COG0071	Belongs to the small heat shock protein (HSP20) family
BCS7_RS21830	COG0071	Belongs to the small heat shock protein (HSP20) family
BCS7_RS21835	COG5645	(Lipo)protein
BCS7_RS21840	COG0823	Involved in the tonB-independent uptake of proteins
BCS7_RS21850	COG2723	6-phospho-beta-galactosidase activity
BCS7_RS21870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCS7_RS21875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCS7_RS21880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCS7_RS21885	COG1116	anion transmembrane transporter activity
BCS7_RS21900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCS7_RS21905	COG0601	transmembrane transport
BCS7_RS21920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCS7_RS21935	COG0561	phosphatase activity
BCS7_RS21945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCS7_RS21950	COG0589	response to stress
BCS7_RS21960	COG0306	phosphate transporter
BCS7_RS21965	COG2081	HI0933 family
BCS7_RS21970	COG2801	Transposase and inactivated derivatives
BCS7_RS21975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCS7_RS21980	COG0415	Belongs to the DNA photolyase family
BCS7_RS21990	COG1902	pentaerythritol trinitrate reductase activity
BCS7_RS22000	COG0300	oxidoreductase activity
BCS7_RS22020	COG1486	melibiose metabolic process
BCS7_RS22030	COG2200	EAL domain
BCS7_RS22045	COG2194	sulfuric ester hydrolase activity
BCS7_RS22050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BCS7_RS22055	COG0194	GDP metabolic process
BCS7_RS22060	COG1758	RNA polymerase activity
BCS7_RS22065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCS7_RS22070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCS7_RS22075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCS7_RS22085	COG2982	Protein involved in outer membrane biogenesis
BCS7_RS22095	COG0765	amino acid transport
BCS7_RS22100	COG0765	amino acid transport
BCS7_RS22105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCS7_RS22110	COG3135	benzoate transporter
BCS7_RS22115	COG1396	sequence-specific DNA binding
BCS7_RS22125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BCS7_RS22130	COG0581	inorganic phosphate transmembrane transporter activity
BCS7_RS22140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCS7_RS22150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCS7_RS22155	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BCS7_RS22165	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BCS7_RS22170	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BCS7_RS22175	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BCS7_RS22180	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BCS7_RS22185	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCS7_RS22190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BCS7_RS22200	COG0356	it plays a direct role in the translocation of protons across the membrane
BCS7_RS22205	COG3312	ion transport
BCS7_RS22210	COG0357	Ribosomal RNA small subunit methyltransferase G
BCS7_RS22215	COG0445	tRNA wobble uridine modification
BCS7_RS22220	COG0716	FMN binding
BCS7_RS22225	COG1522	sequence-specific DNA binding
BCS7_RS22230	COG2502	aspartate--ammonia ligase
BCS7_RS22235	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BCS7_RS22240	COG0714	Associated with various cellular activities
BCS7_RS22245	COG3158	transport of potassium into the cell
BCS7_RS22250	COG0642	Histidine kinase
BCS7_RS22260	COG3111	PFAM Bacterial OB fold (BOF) protein
BCS7_RS22265	COG1869	D-ribose catabolic process
BCS7_RS22270	COG1129	ABC transporter
BCS7_RS22275	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCS7_RS22285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCS7_RS22290	COG1609	Transcriptional regulator
BCS7_RS22315	COG1763	Mo-molybdopterin cofactor biosynthetic process
BCS7_RS22320	COG0746	molybdenum cofactor guanylyltransferase activity
BCS7_RS22325	COG3084	Protein conserved in bacteria
BCS7_RS22330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCS7_RS22340	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCS7_RS22340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCS7_RS22345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BCS7_RS22355	COG3078	GTPase activator activity
BCS7_RS22360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCS7_RS22370	COG3852	Histidine kinase
BCS7_RS22390	COG1011	Hydrolase
BCS7_RS22395	COG1490	D-aminoacyl-tRNA deacylase activity
BCS7_RS22400	COG0456	acetyltransferase
BCS7_RS22405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCS7_RS22410	COG2252	PERMEase
BCS7_RS22415	COG2091	lysine biosynthetic process via aminoadipic acid
BCS7_RS22420	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCS7_RS22425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCS7_RS22425	COG0493	'glutamate synthase
BCS7_RS22455	COG1733	regulation of RNA biosynthetic process
BCS7_RS22460	COG0702	epimerase
BCS7_RS22470	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCS7_RS22475	COG0706	membrane insertase activity
BCS7_RS22480	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BCS7_RS22485	COG0594	ribonuclease P activity
BCS7_RS22490	COG0230	Belongs to the bacterial ribosomal protein bL34 family