locus-tag	class	description
HN015_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HN015_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HN015_RS00015	ENOG410848D	S4 domain protein YaaA
HN015_RS00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HN015_RS00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HN015_RS00035	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HN015_RS00040	ENOG4108UUM	single-stranded DNA-binding protein
HN015_RS00045	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HN015_RS00055	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HN015_RS00060	ENOG4105CDU	Replicative dna helicase
HN015_RS00065	ENOG410605W	Major Facilitator
HN015_RS00080	ENOG4105C5H	ABC transporter
HN015_RS00095	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HN015_RS00105	ENOG4105CK1	PTS System
HN015_RS00120	ENOG4108YYH	Nadph-dependent fmn reductase
HN015_RS00130	ENOG4105DBV	ornithine carbamoyltransferase
HN015_RS00145	ENOG4105D5Q	Arginine ornithine antiporter
HN015_RS00170	ENOG4105KPY	Small multidrug resistance protein
HN015_RS00180	ENOG4108UT2	hemolysin iii
HN015_RS00215	ENOG4105E4P	ATPase (AAA
HN015_RS00265	ENOG4106P55	Transcriptional regulator
HN015_RS00270	ENOG4108UW5	maltose o-acetyltransferase
HN015_RS00280	ENOG4105CV8	reductase
HN015_RS00300	ENOG4105DA5	(ABC) transporter
HN015_RS00305	ENOG4105CZE	histidine utilization repressor
HN015_RS00345	ENOG4108KB2	LysR family Transcriptional regulator
HN015_RS00405	ENOG4105CND	Glycosyl transferase, family 2
HN015_RS00410	ENOG4105CS2	ec 3.2.1.21
HN015_RS00435	ENOG4105CPC	Aldo Keto reductase
HN015_RS00440	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HN015_RS00450	ENOG4105WEF	catalase
HN015_RS00485	ENOG4108A04	Beta-lactamase
HN015_RS00500	ENOG4108M1Z	surface protein
HN015_RS00510	ENOG4105DT3	PTS system, galactitol-specific IIc component
HN015_RS00525	ENOG4105E98	transcriptional regulator DeoR family
HN015_RS00540	ENOG4105D2M	Aldolase
HN015_RS00555	ENOG4108Q3X	Transcriptional regulator
HN015_RS00560	ENOG4105DE4	1-phosphofructokinase
HN015_RS00565	ENOG4105DM4	PTS System
HN015_RS00570	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HN015_RS00580	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN015_RS00585	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
HN015_RS00600	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HN015_RS00615	ENOG4105KT7	mgtC SapB transporter
HN015_RS00620	ENOG4108UZY	PTS System
HN015_RS00625	ENOG4105ETZ	PTS System
HN015_RS00630	ENOG4105F3R	pts system mannose fructose sorbose family iid
HN015_RS00645	ENOG4108TZY	GntR Family Transcriptional Regulator
HN015_RS00655	ENOG4105CK1	PTS System
HN015_RS00670	ENOG41066F8	ROK family
HN015_RS00675	ENOG4105CS2	ec 3.2.1.21
HN015_RS00680	ENOG4105C7K	acetolactate synthase
HN015_RS00715	ENOG4105ETZ	PTS System
HN015_RS00720	ENOG4105F3R	pts system mannose fructose sorbose family iid
HN015_RS00725	ENOG4107R1S	catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine
HN015_RS00755	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HN015_RS00760	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HN015_RS00765	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HN015_RS00780	ENOG4107RHR	regulatoR
HN015_RS00785	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HN015_RS00795	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HN015_RS00815	ENOG4105X1N	Glycosyl transferase family 8
HN015_RS00830	ENOG4105BZW	Glycerate kinase
HN015_RS00835	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HN015_RS00840	ENOG4108TVT	permease
HN015_RS00855	ENOG4108TVJ	Nitroreductase
HN015_RS00865	ENOG4105DWF	phosphomethylpyrimidine kinase
HN015_RS00880	ENOG4105CK1	PTS System
HN015_RS00910	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HN015_RS00915	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN015_RS00945	ENOG4105DZC	cytosine deaminase
HN015_RS00950	ENOG4105E90	ABC transporter
HN015_RS00955	ENOG4108IJ8	ABC transporter
HN015_RS00970	ENOG4105EEM	helicase
HN015_RS01005	ENOG4105I3N	Conserved Protein
HN015_RS01010	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HN015_RS01015	ENOG4105F8V	Hydrolase, tatD family
HN015_RS01020	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
HN015_RS01025	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HN015_RS01030	ENOG4105W42	Veg protein
HN015_RS01035	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HN015_RS01045	ENOG4107YZX	Universal stress protein
HN015_RS01055	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN015_RS01070	ENOG4105C7J	ABC transporter, permease
HN015_RS01085	ENOG4105VZJ	PTS System
HN015_RS01090	ENOG4105VCP	PTS System
HN015_RS01095	ENOG4105CS2	ec 3.2.1.21
HN015_RS01105	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HN015_RS01110	ENOG4105CHR	reductase
HN015_RS01115	ENOG4105D5Q	Arginine ornithine antiporter
HN015_RS01125	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HN015_RS01130	ENOG4108RG0	uracil-dna glycosylase
HN015_RS01135	ENOG4105DSE	periplasmic solute binding protein
HN015_RS01140	ENOG4105FDK	ABC transporter
HN015_RS01145	ENOG4105CC5	ABC transporter
HN015_RS01150	ENOG4105DFT	pur operon repressor
HN015_RS01155	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HN015_RS01185	ENOG4105KTW	ethanolamine utilization protein
HN015_RS01190	ENOG4105KNY	Microcompartments protein
HN015_RS01195	ENOG4105EHR	propanediol utilization protein pduB
HN015_RS01200	ENOG4105DMB	glycerol dehydratase
HN015_RS01205	ENOG4105YCI	dehydratase medium subunit
HN015_RS01210	ENOG4108ZFT	Dehydratase small subunit
HN015_RS01215	ENOG41084PW	diol glycerol dehydratase reactivating factor large subunit
HN015_RS01230	ENOG4105KNY	Microcompartments protein
HN015_RS01235	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
HN015_RS01245	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HN015_RS01260	ENOG4108EKI	Dehydrogenase
HN015_RS01270	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HN015_RS01275	ENOG4105M3W	utilization protein
HN015_RS01280	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN015_RS01285	ENOG4105M2Z	protein tyrosine serine phosphatase
HN015_RS01290	ENOG4105RKW	reductase (By
HN015_RS01295	ENOG4107XVH	Transcriptional regulator
HN015_RS01315	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HN015_RS01320	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HN015_RS01340	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HN015_RS01345	ENOG4105EYW	Ion transport protein
HN015_RS01350	ENOG4105HDK	L-asparaginase
HN015_RS01355	ENOG4105C9K	Endothelin-converting enzyme 1
HN015_RS01360	ENOG4105CU9	asparagine synthetase A
HN015_RS01365	ENOG4105C7N	Xanthine uracil vitamin C permease
HN015_RS01385	ENOG4105DUM	transcriptional regulator, lysR family
HN015_RS01390	ENOG4105HMI	Membrane
HN015_RS01405	ENOG4108HCJ	Hydrolase
HN015_RS01410	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HN015_RS01415	ENOG4105CXT	aspartate transcarbamylase
HN015_RS01420	ENOG4105CD3	dihydroorotase
HN015_RS01425	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HN015_RS01430	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HN015_RS01435	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
HN015_RS01440	ENOG4107EFR	Flavocytochrome c
HN015_RS01455	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HN015_RS01465	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HN015_RS01475	ENOG4108IJ2	phosphate acetyltransferase
HN015_RS01480	ENOG4105G5W	regulator Fur family
HN015_RS01485	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN015_RS01490	ENOG4107U9T	Pfam:Ribonuclease_BN
HN015_RS01500	ENOG4105M2Z	protein tyrosine serine phosphatase
HN015_RS01505	ENOG4105M2Z	protein tyrosine serine phosphatase
HN015_RS01510	ENOG4105MTF	NrdI protein
HN015_RS01515	ENOG4108X4Q	Hydrolase
HN015_RS01520	ENOG4105CIG	ABC transporter
HN015_RS01525	ENOG4105DIM	ABC transporter
HN015_RS01530	ENOG4105C37	(CBS) domain
HN015_RS01535	ENOG4107QM2	Aldo Keto reductase
HN015_RS01555	ENOG4105CI1	PTS System
HN015_RS01560	ENOG4105C87	Aminotransferase class I and II
HN015_RS01565	ENOG4108Z66	YbaK ebsC protein
HN015_RS01570	ENOG4108TZY	GntR Family Transcriptional Regulator
HN015_RS01575	ENOG4107QRI	Phosphoketolase
HN015_RS01580	ENOG4108Z4K	mutator MutT protein
HN015_RS01585	ENOG4108YBP	pseudouridine synthase
HN015_RS01595	ENOG4105EVU	fructokinase
HN015_RS01600	ENOG4108UQV	Membrane
HN015_RS01605	ENOG4108WAV	Transcriptional regulator
HN015_RS01610	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HN015_RS01620	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
HN015_RS01630	ENOG4105DQR	SNARE associated Golgi
HN015_RS01650	ENOG4107SUZ	Sodium/hydrogen exchanger family
HN015_RS01660	ENOG4105CAY	ferredoxin--nadp reductase
HN015_RS01665	ENOG4105E0M	Sulfatase
HN015_RS01690	ENOG4107TS3	membrane protein, TerC
HN015_RS01695	ENOG4105K63	Thioredoxin
HN015_RS01715	ENOG4105C5H	ABC transporter
HN015_RS01725	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
HN015_RS01735	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
HN015_RS01740	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HN015_RS01750	ENOG4105CPN	adenine deaminase
HN015_RS01755	ENOG4105CUB	amino acid
HN015_RS01770	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HN015_RS01775	ENOG4105N80	Ferric uptake regulator, Fur family
HN015_RS01795	ENOG4105CT1	(ABC) transporter
HN015_RS01800	ENOG4105EAD	ABC transporter
HN015_RS01805	ENOG4105DRP	amino acid AbC transporter
HN015_RS01810	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HN015_RS01815	ENOG4105CVJ	phosphoglycerate mutase
HN015_RS01820	ENOG4105E5D	amino acid
HN015_RS01825	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HN015_RS01830	ENOG4105EEM	helicase
HN015_RS01840	ENOG4107FQX	Alpha-acetolactate decarboxylase
HN015_RS01845	ENOG4105CS9	pantothenic acid kinase
HN015_RS01855	ENOG4105IJJ	transcriptional regulator, crp fnr family
HN015_RS01875	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HN015_RS01885	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN015_RS01890	ENOG4105CD8	aminopeptidase N
HN015_RS01900	ENOG4107SFZ	crispr-associated protein
HN015_RS01910	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
HN015_RS01925	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HN015_RS01930	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HN015_RS01935	ENOG4105C0X	amino acid
HN015_RS01940	ENOG4105ESV	Glycosyl transferase, family 4
HN015_RS01945	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HN015_RS01965	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HN015_RS01975	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HN015_RS01980	ENOG4105BZU	Histidine kinase
HN015_RS01990	ENOG4105C8U	phosphate abc transporter
HN015_RS01995	ENOG4105E2Z	phosphate ABC transporter (Permease
HN015_RS02000	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HN015_RS02005	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HN015_RS02010	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HN015_RS02020	ENOG41086DT	Membrane protein of unknown function
HN015_RS02025	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
HN015_RS02030	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HN015_RS02035	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HN015_RS02045	ENOG4105C3M	thioredoxin reductase
HN015_RS02060	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HN015_RS02065	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HN015_RS02070	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HN015_RS02075	ENOG4105CHW	UPF0052 protein
HN015_RS02080	ENOG4105CIE	May be required for sporulation (By similarity)
HN015_RS02095	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HN015_RS02105	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HN015_RS02115	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HN015_RS02120	ENOG4105BZA	Phosphoglycerate kinase
HN015_RS02125	ENOG4105CP7	Triose-phosphate isomerase
HN015_RS02130	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HN015_RS02135	ENOG4105XZU	Preprotein translocase, subunit SecG
HN015_RS02140	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HN015_RS02145	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HN015_RS02160	ENOG410667J	hydrolase
HN015_RS02165	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HN015_RS02170	ENOG4105K8N	protein family UPF0079, ATPase
HN015_RS02175	ENOG4108MK9	spermidine N(1)-acetyltransferase
HN015_RS02180	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HN015_RS02185	ENOG4105EP9	oxidoreductase
HN015_RS02190	ENOG4105D4A	Cell wall formation (By similarity)
HN015_RS02195	ENOG4105C8B	TIGR00159 family
HN015_RS02205	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HN015_RS02210	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HN015_RS02240	ENOG4108TZY	GntR Family Transcriptional Regulator
HN015_RS02250	ENOG4105ETZ	PTS System
HN015_RS02255	ENOG4105F3R	pts system mannose fructose sorbose family iid
HN015_RS02260	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HN015_RS02265	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HN015_RS02275	ENOG4105PY6	Phenolic acid decarboxylase
HN015_RS02280	ENOG4105U3E	Transcriptional regulator
HN015_RS02285	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HN015_RS02295	ENOG4105C5S	asparaginyl-tRNA synthetase
HN015_RS02300	ENOG4105DZW	Dipeptidase
HN015_RS02305	ENOG4105WZW	rhodanese family
HN015_RS02315	ENOG4108JJB	ABC transporter
HN015_RS02325	ENOG4105V9V	Short-chain dehydrogenase reductase Sdr
HN015_RS02350	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HN015_RS02355	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HN015_RS02360	ENOG4105C3K	feS assembly ATPase SufC
HN015_RS02365	ENOG4105JRK	feS assembly protein SufD
HN015_RS02375	ENOG4107YH3	SUF system FeS assembly protein, NifU family
HN015_RS02380	ENOG4105DIW	FeS assembly protein SUFB
HN015_RS02385	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HN015_RS02395	ENOG4105C4R	Atp-dependent dna helicase
HN015_RS02400	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
HN015_RS02405	ENOG4107PP3	Acetylornithine deacetylase
HN015_RS02410	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HN015_RS02415	ENOG4105E2A	Dehydrogenase
HN015_RS02445	ENOG4107QNK	)-transporter
HN015_RS02450	ENOG4107BMA	Transglycosylase associated protein
HN015_RS02460	ENOG4105X1N	Glycosyl transferase family 8
HN015_RS02485	ENOG4105DQ6	Transposase
HN015_RS02495	ENOG4105DC8	reductase
HN015_RS02555	ENOG4105KPE	licD family
HN015_RS02565	ENOG4108M1A	Chitin-binding protein
HN015_RS02575	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
HN015_RS02580	ENOG4105DWF	phosphomethylpyrimidine kinase
HN015_RS02585	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HN015_RS02595	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HN015_RS02605	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
HN015_RS02615	ENOG4105HTX	biosynthesis protein
HN015_RS02620	ENOG4108QV3	biosynthesis protein
HN015_RS02625	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
HN015_RS02630	ENOG4105D3Q	Sugar transferase
HN015_RS02640	ENOG4107SJB	teichoic acid biosynthesis
HN015_RS02660	ENOG4105D5D	udp-galactopyranose mutase
HN015_RS02680	ENOG4108TZY	GntR Family Transcriptional Regulator
HN015_RS02690	ENOG4108UZY	PTS System
HN015_RS02695	ENOG4105ETZ	PTS System
HN015_RS02700	ENOG4105F3R	pts system mannose fructose sorbose family iid
HN015_RS02705	ENOG4107R1S	catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine
HN015_RS02730	ENOG4105NA0	Transcriptional regulator
HN015_RS02745	ENOG4105C59	p-type ATPase
HN015_RS02750	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HN015_RS02765	ENOG4107R7I	amino acid
HN015_RS02780	ENOG4105EE0	oxidoreductase
HN015_RS02785	ENOG4105FDU	atp-dependent rna helicase
HN015_RS02810	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
HN015_RS02815	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HN015_RS02825	ENOG4105KRI	phosphocarrier protein (HPr
HN015_RS02830	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HN015_RS02835	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
HN015_RS02840	ENOG4105BZF	Glycosyl transferase (Group 1
HN015_RS02845	ENOG4105W2C	Glycosyl transferase
HN015_RS02980	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HN015_RS02985	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN015_RS02995	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HN015_RS03000	ENOG4105C8T	Leucyl-tRNA synthetase
HN015_RS03015	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HN015_RS03020	ENOG4107YZX	Universal stress protein
HN015_RS03035	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HN015_RS03040	ENOG4105CG3	alpha amylase, catalytic region
HN015_RS03045	ENOG4107414	GntR family transcriptional regulator
HN015_RS03050	ENOG4105C5Y	PTS System
HN015_RS03055	ENOG4105ZMH	deoxynucleoside kinase
HN015_RS03080	ENOG4105CAQ	asparagine synthetase
HN015_RS03085	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HN015_RS03095	ENOG4105CG9	aspartate racemase
HN015_RS03100	ENOG4105ZT7	DNA-entry nuclease
HN015_RS03105	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HN015_RS03110	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HN015_RS03115	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
HN015_RS03140	ENOG4108IMY	Transcriptional regulator
HN015_RS03190	ENOG4108UUM	single-stranded DNA-binding protein
HN015_RS03215	ENOG4106CVF	DNA replication protein
HN015_RS03385	ENOG41066F8	ROK family
HN015_RS03395	ENOG4107RJ1	sodium solute
HN015_RS03430	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HN015_RS03435	ENOG4108QVC	Component IIC
HN015_RS03445	ENOG4105CS2	ec 3.2.1.21
HN015_RS03470	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HN015_RS03475	ENOG4105DM4	PTS System
HN015_RS03495	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HN015_RS03505	ENOG4107QNK	)-transporter
HN015_RS03520	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
HN015_RS03525	ENOG4105DCF	alanine dehydrogenase
HN015_RS03535	ENOG4107R7I	amino acid
HN015_RS03540	ENOG4105EPD	Oligopeptide transporter, Opt family
HN015_RS03550	ENOG4105DZW	Dipeptidase
HN015_RS03575	ENOG4105CK1	PTS System
HN015_RS03600	ENOG4105DET	Rhamnulokinase
HN015_RS03605	ENOG4105C54	Major Facilitator superfamily
HN015_RS03620	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HN015_RS03625	ENOG4105C72	UPF0176 protein
HN015_RS03630	ENOG4105VPX	protein, conserved in bacteria
HN015_RS03655	ENOG4105CQ4	Transcriptional regulator
HN015_RS03660	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HN015_RS03665	ENOG4107RBJ	symporter
HN015_RS03680	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HN015_RS03685	ENOG4105CMR	udp-glucose 4-epimerase
HN015_RS03690	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
HN015_RS03700	ENOG4105E5D	amino acid
HN015_RS03730	ENOG4107S5I	aldo keto reductase
HN015_RS03735	ENOG4105C75	arginyL-tRNA synthetase
HN015_RS03745	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HN015_RS03750	ENOG4105BZ4	penicillin-binding protein
HN015_RS03755	ENOG4105WZB	UPF0342 protein
HN015_RS03760	ENOG4107VRP	DNA repair exonuclease
HN015_RS03765	ENOG4106D4I	domain protein
HN015_RS03775	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HN015_RS03785	ENOG4105K59	histidine triad (HIT) protein
HN015_RS03800	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HN015_RS03810	ENOG4108VDD	TRNA binding domain protein
HN015_RS03820	ENOG4105DFU	Cell wall formation (By similarity)
HN015_RS03825	ENOG4105HFZ	Membrane
HN015_RS03830	ENOG4105C2M	dna polymerase I
HN015_RS03835	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HN015_RS03845	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HN015_RS03860	ENOG4105C22	threonyL-tRNA synthetase
HN015_RS03865	ENOG4108HRK	Histidine kinase
HN015_RS03870	ENOG4105DY9	regulatoR
HN015_RS03875	ENOG4105VAW	lrga family
HN015_RS03885	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HN015_RS03890	ENOG4105VJV	50s ribosomal protein L35
HN015_RS03895	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HN015_RS03900	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
HN015_RS03905	ENOG4105CQW	ribosome biogenesis GTPase YqeH
HN015_RS03910	ENOG410812S	Rna-binding protein
HN015_RS03915	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HN015_RS03920	ENOG4108WF2	Metal Dependent Phosphohydrolase
HN015_RS03925	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HN015_RS03930	ENOG4105DXX	methyltransferase
HN015_RS03935	ENOG4105CDE	UPF0348 protein
HN015_RS03940	ENOG4105KNH	Nucleic acid-binding protein
HN015_RS03945	ENOG41067VY	50S ribosomal protein L32
HN015_RS03950	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HN015_RS03955	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN015_RS03960	ENOG4105GR3	Histidine kinase
HN015_RS03975	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
HN015_RS03980	ENOG410855V	Acylphosphatase
HN015_RS03985	ENOG4108RWN	rrna methyltransferase
HN015_RS04000	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HN015_RS04005	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HN015_RS04020	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HN015_RS04025	ENOG4105EJV	Membrane
HN015_RS04030	ENOG4107RF6	penicillin-binding protein
HN015_RS04035	ENOG4105WDJ	50S ribosomal protein L33
HN015_RS04040	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HN015_RS04055	ENOG4105DKQ	ROK family
HN015_RS04060	ENOG4105WZW	rhodanese family
HN015_RS04070	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HN015_RS04075	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HN015_RS04080	ENOG4105CXI	aluminum resistance protein
HN015_RS04085	ENOG4105KV4	Transcriptional regulator
HN015_RS04090	ENOG4105C5F	glutamine synthetase
HN015_RS04130	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HN015_RS04140	ENOG4105K46	50S ribosomal protein l27
HN015_RS04145	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HN015_RS04150	ENOG4105VBF	alkaline shock protein
HN015_RS04155	ENOG4105M7K	Involved in the transcription termination process (By similarity)
HN015_RS04160	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HN015_RS04165	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HN015_RS04170	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HN015_RS04180	ENOG4105DX0	Hemolysin A
HN015_RS04185	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HN015_RS04190	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HN015_RS04200	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HN015_RS04205	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HN015_RS04210	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HN015_RS04215	ENOG4105C25	Primosomal protein n'
HN015_RS04220	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HN015_RS04225	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HN015_RS04235	ENOG4105D9P	serine threonine protein kinase
HN015_RS04240	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HN015_RS04245	ENOG4105DJV	ribulose-phosphate 3-epimerase
HN015_RS04255	ENOG4105VB9	50S ribosomal protein l28
HN015_RS04270	ENOG4105CB5	ATP-dependent DNA helicase recG
HN015_RS04275	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HN015_RS04280	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HN015_RS04285	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HN015_RS04290	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HN015_RS04295	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HN015_RS04300	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
HN015_RS04305	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HN015_RS04310	ENOG4105K5M	30s ribosomal protein S16
HN015_RS04315	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HN015_RS04320	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HN015_RS04325	ENOG41083J0	(ABC) transporter
HN015_RS04330	ENOG4105C4B	ABC transporter, permease
HN015_RS04335	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HN015_RS04355	ENOG4105K8R	UPF0145 protein
HN015_RS04365	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HN015_RS04370	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HN015_RS04380	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HN015_RS04385	ENOG4105CHR	reductase
HN015_RS04390	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HN015_RS04395	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HN015_RS04405	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HN015_RS04410	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HN015_RS04415	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HN015_RS04420	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HN015_RS04425	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN015_RS04460	ENOG4108IMY	Transcriptional regulator
HN015_RS04545	ENOG4108UUM	single-stranded DNA-binding protein
HN015_RS04590	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
HN015_RS04600	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HN015_RS04605	ENOG4105VPS	UPF0291 protein
HN015_RS04610	ENOG4105VXM	UPF0154 protein
HN015_RS04615	ENOG4105F6E	Acyl-transferase
HN015_RS04620	ENOG41060K3	Methyltransferase
HN015_RS04625	ENOG4105VC4	domain protein
HN015_RS04630	ENOG4105C5I	Dehydrogenase
HN015_RS04635	ENOG4105CE9	30S ribosomal protein S2
HN015_RS04640	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HN015_RS04645	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HN015_RS04650	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HN015_RS04655	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HN015_RS04660	ENOG4105KNE	Phosphatidate cytidylyltransferase
HN015_RS04665	ENOG4105DZP	Membrane-associated zinc metalloprotease
HN015_RS04670	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HN015_RS04675	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HN015_RS04680	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HN015_RS04685	ENOG4105CHV	Transcription elongation factor NusA
HN015_RS04690	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
HN015_RS04700	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HN015_RS04705	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HN015_RS04710	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HN015_RS04715	ENOG4105DTN	riboflavin biosynthesis protein ribF
HN015_RS04720	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HN015_RS04725	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HN015_RS04730	ENOG4105CFG	Acts as a chaperone (By similarity)
HN015_RS04735	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HN015_RS04740	ENOG4105KAV	tspo and mbr like protein
HN015_RS04745	ENOG4105WG9	Conserved Protein
HN015_RS04755	ENOG4105CJ1	ABC, transporter
HN015_RS04770	ENOG4107RSM	transcriptional regulator
HN015_RS04775	ENOG4105FCD	Major Facilitator
HN015_RS04780	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HN015_RS04785	ENOG410807C	QueT transporter
HN015_RS04800	ENOG4108URH	decarboxylase
HN015_RS04810	ENOG4105E5D	amino acid
HN015_RS04815	ENOG4105CNT	hydrolase family 2
HN015_RS04830	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HN015_RS04835	ENOG4105DZW	Dipeptidase
HN015_RS04840	ENOG41069HH	4-oxalocrotonate tautomerase
HN015_RS04845	ENOG4108KP7	hydrolase
HN015_RS04850	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HN015_RS04855	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HN015_RS04870	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HN015_RS04875	ENOG4105DVT	helicase
HN015_RS04890	ENOG4105BZ4	penicillin-binding protein
HN015_RS04895	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
HN015_RS04900	ENOG4108UKS	UPF0398 protein
HN015_RS04905	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
HN015_RS04915	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HN015_RS04920	ENOG4107VFR	oxidoreductase
HN015_RS04930	ENOG4105CKU	formyltetrahydrofolate synthetase
HN015_RS04935	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HN015_RS04940	ENOG4105C34	Pseudouridine synthase
HN015_RS04945	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HN015_RS04955	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HN015_RS04970	ENOG4105EPR	degv family
HN015_RS04975	ENOG4106A8V	Protein CrcB homolog
HN015_RS04980	ENOG4105WMR	Protein CrcB homolog
HN015_RS05000	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HN015_RS05005	ENOG4108KGH	TRANSCRIPTIONal
HN015_RS05010	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HN015_RS05015	ENOG4105C2C	drug resistance transporter, Bcr CflA
HN015_RS05025	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HN015_RS05030	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HN015_RS05040	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HN015_RS05045	ENOG4105EEI	dihydropteroate synthase
HN015_RS05050	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HN015_RS05055	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HN015_RS05060	ENOG4105EUJ	GTP cyclohydrolase i
HN015_RS05065	ENOG4105EUJ	GTP cyclohydrolase i
HN015_RS05075	ENOG4107SC7	Inner membrane transporter yjeM
HN015_RS05080	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HN015_RS05085	ENOG4105E0X	reductase
HN015_RS05090	ENOG4105BZW	Glycerate kinase
HN015_RS05095	ENOG4107QQ0	gntp family
HN015_RS05100	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HN015_RS05105	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
HN015_RS05110	ENOG4105DND	Transcriptional regulator
HN015_RS05115	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HN015_RS05120	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HN015_RS05125	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HN015_RS05135	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HN015_RS05140	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HN015_RS05145	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN015_RS05150	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HN015_RS05155	ENOG4105C79	DNA protecting protein DprA
HN015_RS05160	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HN015_RS05200	ENOG4108R6W	Transcriptional regulator, ARAC family
HN015_RS05205	ENOG4107HQ7	repeat protein
HN015_RS05210	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HN015_RS05215	ENOG4105CI1	PTS System
HN015_RS05220	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HN015_RS05225	ENOG4105CHU	acetyl-coa acetyltransferase
HN015_RS05245	ENOG4105DA5	(ABC) transporter
HN015_RS05275	ENOG4108IG5	Transcriptional regulator
HN015_RS05280	ENOG4105C12	Phosphoribosylglycinamide synthetase
HN015_RS05285	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HN015_RS05290	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HN015_RS05295	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HN015_RS05300	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HN015_RS05305	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
HN015_RS05310	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HN015_RS05315	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
HN015_RS05320	ENOG4105C8V	SAICAR synthetase
HN015_RS05325	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HN015_RS05330	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HN015_RS05355	ENOG4105DA5	(ABC) transporter
HN015_RS05360	ENOG41067QW	Transcriptional regulator
HN015_RS05370	ENOG4108WCX	response regulator
HN015_RS05380	ENOG4105BZ1	(ABC) transporter
HN015_RS05400	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HN015_RS05410	ENOG4105D06	uba thif-type nad fad binding protein
HN015_RS05415	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HN015_RS05425	ENOG4105CK2	sodium dicarboxylate symporter
HN015_RS05430	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HN015_RS05480	ENOG4105CS2	ec 3.2.1.21
HN015_RS05485	ENOG4105C5Y	PTS System
HN015_RS05505	ENOG4107QTZ	amino acid
HN015_RS05510	ENOG41080E8	Transcriptional regulator, Spx MgsR family
HN015_RS05520	ENOG4105VSD	UPF0346 protein
HN015_RS05530	ENOG41090WU	lipolytic protein G-D-S-L family
HN015_RS05535	ENOG4108RCR	degv family
HN015_RS05540	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HN015_RS05545	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HN015_RS05550	ENOG4105C5H	ABC transporter
HN015_RS05555	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HN015_RS05560	ENOG4108JYZ	YitT family
HN015_RS05575	ENOG41068YB	TPR repeat-containing protein
HN015_RS05585	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HN015_RS05590	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HN015_RS05595	ENOG4105CAT	Cytidine monophosphate kinase
HN015_RS05605	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HN015_RS05615	ENOG4105FE9	pseudouridine synthase
HN015_RS05620	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HN015_RS05625	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HN015_RS05645	ENOG4108VMM	UPF0756 membrane protein
HN015_RS05650	ENOG4105CA9	Pyruvate kinase
HN015_RS05655	ENOG4105CTQ	phosphohexokinase
HN015_RS05660	ENOG4105C0B	DNA polymerase III (alpha subunit)
HN015_RS05670	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HN015_RS05675	ENOG4105EGD	dinuclear metal center protein, YbgI family
HN015_RS05685	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HN015_RS05690	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HN015_RS05695	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HN015_RS05700	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HN015_RS05705	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
HN015_RS05710	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HN015_RS05720	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HN015_RS05725	ENOG4105C9A	Phoh family
HN015_RS05735	ENOG4105VCC	30S ribosomal protein S21
HN015_RS05740	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HN015_RS05750	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HN015_RS05755	ENOG4107SJB	teichoic acid biosynthesis
HN015_RS05770	ENOG4105C9M	aspartyl-trna synthetase
HN015_RS05775	ENOG4105CUT	histidyl-tRNA synthetase
HN015_RS05780	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HN015_RS05785	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
HN015_RS05790	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HN015_RS05795	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HN015_RS05805	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HN015_RS05810	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HN015_RS05835	ENOG4105CHM	Aminotransferase
HN015_RS05850	ENOG4107YB6	acetyltransferase, (GNAT) family
HN015_RS05855	ENOG4105BZ1	(ABC) transporter
HN015_RS05865	ENOG4108DBC	nitroreductase
HN015_RS05910	ENOG4107BMA	Transglycosylase associated protein
HN015_RS05925	ENOG4107PP3	Acetylornithine deacetylase
HN015_RS05940	ENOG4105CH6	catalase
HN015_RS05950	ENOG4105DA5	(ABC) transporter
HN015_RS05965	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HN015_RS05970	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HN015_RS05975	ENOG4108IXY	short-chain dehydrogenase reductase
HN015_RS05980	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HN015_RS05990	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HN015_RS05995	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HN015_RS06000	ENOG4105CDA	abc transporter atp-binding protein
HN015_RS06005	ENOG4105E5Q	amino acid AbC transporter
HN015_RS06020	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HN015_RS06025	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HN015_RS06030	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HN015_RS06035	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HN015_RS06050	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HN015_RS06055	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HN015_RS06070	ENOG4108UK2	deaminase
HN015_RS06075	ENOG4105KQC	Competence protein
HN015_RS06080	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HN015_RS06085	ENOG4106H78	methyltransferase
HN015_RS06090	ENOG4105WUC	UPF0298 protein
HN015_RS06095	ENOG4105CNI	cell division protein FtsW
HN015_RS06100	ENOG4105CI3	gtp-binding protein typa
HN015_RS06105	ENOG4105ECY	inositol monophosphatase
HN015_RS06110	ENOG4105WBI	UPF0223 protein
HN015_RS06115	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HN015_RS06140	ENOG4105DM4	PTS System
HN015_RS06145	ENOG4105DE4	1-phosphofructokinase
HN015_RS06150	ENOG4105E98	transcriptional regulator DeoR family
HN015_RS06155	ENOG4106F5Q	Membrane
HN015_RS06160	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HN015_RS06165	ENOG4105C7H	Helicase, RecD TraA family
HN015_RS06180	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HN015_RS06190	ENOG4105C3J	Cysteine desulfurase
HN015_RS06195	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HN015_RS06205	ENOG4108YZ4	nudix hydrolase
HN015_RS06210	ENOG4105VEQ	Cold shock protein
HN015_RS06215	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HN015_RS06225	ENOG4105DBK	s4 domain protein
HN015_RS06240	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HN015_RS06245	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
HN015_RS06250	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HN015_RS06255	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HN015_RS06260	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HN015_RS06265	ENOG4105CJN	penicillin-binding protein
HN015_RS06275	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HN015_RS06280	ENOG4108V6E	Cell division protein mraZ
HN015_RS06290	ENOG4105CNU	cell division protein FtsK
HN015_RS06295	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HN015_RS06310	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HN015_RS06315	ENOG4106N3A	copper homeostasis protein cutc
HN015_RS06320	ENOG4105CJW	magnesium transporter
HN015_RS06325	ENOG4105EMS	pseudouridine synthase
HN015_RS06330	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HN015_RS06350	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HN015_RS06355	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
HN015_RS06360	ENOG4108RQ5	Beta-lactamase domain-containing protein
HN015_RS06435	ENOG4107QUF	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HN015_RS06440	ENOG4105DQR	SNARE associated Golgi
HN015_RS06450	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
HN015_RS06455	ENOG4105MMD	transcriptional regulator
HN015_RS06490	ENOG4106855	Competence protein
HN015_RS06510	ENOG4105CDY	transcriptional regulatory protein
HN015_RS06515	ENOG4107STQ	Multicopper oxidase
HN015_RS06525	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HN015_RS06535	ENOG4105C83	adenylosuccinate lyase
HN015_RS06540	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HN015_RS06545	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HN015_RS06550	ENOG4105CV8	reductase
HN015_RS06555	ENOG4105KVH	Transcriptional regulator
HN015_RS06565	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HN015_RS06570	ENOG4105ETE	Transcriptional regulator (LacI family
HN015_RS06575	ENOG4105DC7	peptidase M24
HN015_RS06590	ENOG4105D8X	mechanosensitive ion channel
HN015_RS06595	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HN015_RS06600	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HN015_RS06610	ENOG4105K63	Thioredoxin
HN015_RS06615	ENOG4105C98	muts2 protein
HN015_RS06620	ENOG4105VPH	UPF0473 protein
HN015_RS06625	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HN015_RS06630	ENOG4105VBH	UPF0297 protein
HN015_RS06635	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HN015_RS06640	ENOG4105C1J	atp-dependent rna helicase
HN015_RS06650	ENOG4105SFS	phosphoesterase RecJ domain protein
HN015_RS06655	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HN015_RS06660	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HN015_RS06665	ENOG4105VIE	preprotein translocase, subunit YajC
HN015_RS06670	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HN015_RS06675	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HN015_RS06680	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HN015_RS06685	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HN015_RS06690	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HN015_RS06695	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HN015_RS06700	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HN015_RS06710	ENOG4105CEV	competence damage-inducible protein
HN015_RS06715	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HN015_RS06725	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
HN015_RS06740	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HN015_RS06745	ENOG4107R0W	ABC transporter
HN015_RS06750	ENOG4105CDA	abc transporter atp-binding protein
HN015_RS06755	ENOG4105E5Q	amino acid AbC transporter
HN015_RS06770	ENOG4105W5Q	DNA repair protein (RadC
HN015_RS06775	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HN015_RS06780	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HN015_RS06790	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HN015_RS06795	ENOG4105C3J	Cysteine desulfurase
HN015_RS06800	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
HN015_RS06805	ENOG4108ZGC	gaf domain protein
HN015_RS06810	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HN015_RS06815	ENOG4105D1H	recombination factor protein RarA
HN015_RS06830	ENOG4107YZX	Universal stress protein
HN015_RS06840	ENOG4105CPF	Cell wall formation (By similarity)
HN015_RS06850	ENOG4105CUB	amino acid
HN015_RS06865	ENOG4105DVE	abc transporter atp-binding protein
HN015_RS06870	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
HN015_RS06875	ENOG4105D01	(LipO)protein
HN015_RS06880	ENOG4108UMI	ABC transporter, permease
HN015_RS06885	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HN015_RS06890	ENOG4105CNI	cell division protein FtsW
HN015_RS06900	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HN015_RS06905	ENOG4106778	Protein of unknown function (DUF1146)
HN015_RS06910	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HN015_RS06915	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HN015_RS06920	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HN015_RS06925	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HN015_RS06930	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HN015_RS06935	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
HN015_RS06940	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HN015_RS06945	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
HN015_RS06960	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HN015_RS06965	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HN015_RS06970	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HN015_RS06975	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HN015_RS06985	ENOG4107104	thymidine kinase
HN015_RS06990	ENOG4105DMS	mur ligase
HN015_RS06995	ENOG4105F1K	Glutamine amidotransferase
HN015_RS07000	ENOG4105DG6	mannose-6-phosphate isomerase
HN015_RS07010	ENOG4105BZ1	(ABC) transporter
HN015_RS07030	ENOG4105KP9	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HN015_RS07050	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HN015_RS07055	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HN015_RS07065	ENOG4107QYV	phosphohexose isomerase
HN015_RS07070	ENOG4105CSC	Glucose uptake protein
HN015_RS07080	ENOG4105BZU	Histidine kinase
HN015_RS07085	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN015_RS07095	ENOG41068KG	domain protein
HN015_RS07100	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
HN015_RS07110	ENOG4105C6Z	Gluconate
HN015_RS07115	ENOG4105CMG	Carbohydrate kinase
HN015_RS07125	ENOG4106KNT	transcriptional regulator
HN015_RS07150	ENOG41089G2	accessory Sec system protein Asp2
HN015_RS07160	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HN015_RS07165	ENOG4108MGR	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity)
HN015_RS07185	ENOG4105E0M	Sulfatase
HN015_RS07190	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HN015_RS07195	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
HN015_RS07200	ENOG4105C02	permease
HN015_RS07205	ENOG4105EVI	UPF0374 protein
HN015_RS07210	ENOG410902V	Modulates RecA activity (By similarity)
HN015_RS07240	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN015_RS07255	ENOG41082EK	Restriction modification system DNA (Specificity
HN015_RS07305	ENOG4105C2M	dna polymerase I
HN015_RS07360	ENOG4105CAR	Terminase, large subunit
HN015_RS07375	ENOG4105EFC	phage portal protein HK97 family
HN015_RS07400	ENOG4105XSJ	toxin secretion phage lysis holin
HN015_RS07430	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HN015_RS07435	ENOG4105CBD	Diacylglycerol kinase
HN015_RS07440	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HN015_RS07445	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HN015_RS07450	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HN015_RS07460	ENOG4105C4R	Atp-dependent dna helicase
HN015_RS07465	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HN015_RS07470	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
HN015_RS07475	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HN015_RS07510	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HN015_RS07525	ENOG4105CUB	amino acid
HN015_RS07550	ENOG4108UJD	30S ribosomal protein S9
HN015_RS07555	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HN015_RS07560	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HN015_RS07570	ENOG4108JJB	ABC transporter
HN015_RS07575	ENOG4108JJB	ABC transporter
HN015_RS07580	ENOG4108ZT0	50S ribosomal protein l17
HN015_RS07585	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HN015_RS07590	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HN015_RS07595	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HN015_RS07600	ENOG41067V7	50S ribosomal protein L36
HN015_RS07605	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HN015_RS07615	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HN015_RS07620	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HN015_RS07625	ENOG41084KY	50S ribosomal protein L30
HN015_RS07630	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HN015_RS07635	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HN015_RS07640	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HN015_RS07645	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HN015_RS07650	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HN015_RS07655	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HN015_RS07660	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HN015_RS07665	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HN015_RS07670	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HN015_RS07675	ENOG41082SA	50s ribosomal protein l29
HN015_RS07680	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HN015_RS07685	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HN015_RS07690	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HN015_RS07695	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HN015_RS07700	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HN015_RS07705	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HN015_RS07710	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HN015_RS07715	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HN015_RS07720	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HN015_RS07725	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HN015_RS07730	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HN015_RS07735	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HN015_RS07745	ENOG4105DU0	nucleoside hydrolase
HN015_RS07750	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HN015_RS07755	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HN015_RS07760	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HN015_RS07765	ENOG4105KEX	transcriptional regulator, ctsr
HN015_RS07770	ENOG4105C7K	acetolactate synthase
HN015_RS07810	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HN015_RS07815	ENOG4105ZMH	deoxynucleoside kinase
HN015_RS07820	ENOG4108IQI	permease
HN015_RS07835	ENOG4108KGH	TRANSCRIPTIONal
HN015_RS07845	ENOG4105DWK	Membrane
HN015_RS07850	ENOG4105VEQ	Cold shock protein
HN015_RS07855	ENOG4105PGM	cation diffusion facilitator family transporter
HN015_RS07870	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HN015_RS07880	ENOG4105EMS	pseudouridine synthase
HN015_RS07900	ENOG4105DZW	Dipeptidase
HN015_RS07910	ENOG4108IUX	(ABC) transporter
HN015_RS07920	ENOG4105T6C	Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps
HN015_RS07940	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
HN015_RS07950	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HN015_RS07960	ENOG41072GX	Peptidase M22 Glycoprotease
HN015_RS07965	ENOG4105CMR	udp-glucose 4-epimerase
HN015_RS07980	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
HN015_RS07985	ENOG4105FA2	dna polymerase iii
HN015_RS07990	ENOG4105X0R	protein from nitrogen regulatory protein P-II
HN015_RS07995	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HN015_RS08000	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HN015_RS08005	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HN015_RS08010	ENOG4105C6E	dna polymerase iii
HN015_RS08025	ENOG4107Y49	methyltransferase
HN015_RS08030	ENOG41067VN	Glutaredoxin
HN015_RS08035	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HN015_RS08040	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HN015_RS08045	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HN015_RS08050	ENOG4108VZM	50s ribosomal protein L10
HN015_RS08055	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HN015_RS08060	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HN015_RS08065	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HN015_RS08075	ENOG4107FTN	50S ribosomal protein L33
HN015_RS08085	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HN015_RS08090	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HN015_RS08095	ENOG4105C8N	cysteinyl-tRNA synthetase
HN015_RS08100	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HN015_RS08105	ENOG4105CTP	PilT protein domain protein
HN015_RS08110	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HN015_RS08125	ENOG4105E66	phosphoriboisomerase A
HN015_RS08130	ENOG4105CTZ	aminopeptidase c
HN015_RS08135	ENOG4108K79	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HN015_RS08150	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HN015_RS08155	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HN015_RS08160	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HN015_RS08175	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HN015_RS08185	ENOG4105F3R	pts system mannose fructose sorbose family iid
HN015_RS08190	ENOG4105ETZ	PTS System
HN015_RS08205	ENOG410906U	SprT-like
HN015_RS08225	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
HN015_RS08230	ENOG4105DAP	Nicotinate phosphoribosyltransferase
HN015_RS08245	ENOG4105CE4	GlcNAc 6-P deacetylase
HN015_RS08275	ENOG4105DUX	Transporter
HN015_RS08315	ENOG4105CRK	lysyL-tRNA synthetase
HN015_RS08320	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HN015_RS08325	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HN015_RS08340	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HN015_RS08345	ENOG41060GV	RNA binding s1 domain protein
HN015_RS08355	ENOG41082I2	s4 domain protein
HN015_RS08365	ENOG4108JA2	transcriptioN-repair coupling factor
HN015_RS08370	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HN015_RS08375	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HN015_RS08390	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
HN015_RS08410	ENOG4105C1J	atp-dependent rna helicase
HN015_RS08415	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HN015_RS08425	ENOG4105D0M	Protease HtpX homolog
HN015_RS08430	ENOG4108V0P	LemA family
HN015_RS08435	ENOG4108Z6X	(sortase) family
HN015_RS08445	ENOG41082DI	50s ribosomal protein l31
HN015_RS08450	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HN015_RS08455	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HN015_RS08460	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HN015_RS08465	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
HN015_RS08475	ENOG4105DCI	Phosphohydrolase
HN015_RS08495	ENOG4105E2R	ROK family
HN015_RS08540	ENOG4107XGZ	Hydrolase
HN015_RS08555	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
HN015_RS08565	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HN015_RS08570	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
HN015_RS08580	ENOG41080Y5	BioY family
HN015_RS08590	ENOG4108SAX	Membrane
HN015_RS08610	ENOG4107SJB	teichoic acid biosynthesis
HN015_RS08615	ENOG4108A04	Beta-lactamase
HN015_RS08625	ENOG4105CKK	Glycosyl transferase, family 2
HN015_RS08635	ENOG4105EY8	ABC transporter
HN015_RS08645	ENOG4107SJB	teichoic acid biosynthesis
HN015_RS08650	ENOG4105CKK	Glycosyl transferase, family 2
HN015_RS08655	ENOG4105WH5	Teichoic acid glycosylation protein
HN015_RS08660	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HN015_RS08665	ENOG4105CGK	Exodeoxyribonuclease III
HN015_RS08675	ENOG4105C98	muts2 protein
HN015_RS08680	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
HN015_RS08695	ENOG4105C9Q	fumarate hydratase class II
HN015_RS08700	ENOG4105C6K	Malic enzyme
HN015_RS08705	ENOG4105C5Q	Transcriptional regulator
HN015_RS08715	ENOG4105CPC	Aldo Keto reductase
HN015_RS08720	ENOG4105CMQ	Chloride channel
HN015_RS08740	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HN015_RS08745	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HN015_RS08750	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HN015_RS08810	ENOG4105DPN	Oligoendopeptidase f
HN015_RS08825	ENOG4105CT4	transporter
HN015_RS08835	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HN015_RS08840	ENOG4105C94	Transporter
HN015_RS08845	ENOG4108UW5	maltose o-acetyltransferase
HN015_RS08850	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HN015_RS08865	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HN015_RS08870	ENOG4108UZ3	Transporter
HN015_RS08880	ENOG4105C5H	ABC transporter
HN015_RS08890	ENOG4107QUY	Guanine deaminase
HN015_RS08895	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HN015_RS08910	ENOG4105R40	Glycine betaine carnitine choline
HN015_RS08915	ENOG4108HQR	Glycine betaine
HN015_RS08930	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HN015_RS08935	ENOG4105D9R	oxidoreductase
HN015_RS08940	ENOG4105BZ1	(ABC) transporter
HN015_RS08950	ENOG4105VDH	Dihydroxyacetone kinase
HN015_RS08955	ENOG4108UTZ	Dihydroxyacetone kinase
HN015_RS08960	ENOG4105CMT	Dihydroxyacetone kinase
HN015_RS08975	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HN015_RS09005	ENOG4107BMA	Transglycosylase associated protein
HN015_RS09010	ENOG4108FN7	Aldo keto reductase
HN015_RS09015	ENOG4108KP7	hydrolase
HN015_RS09020	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HN015_RS09025	ENOG4107YDN	peptide deformylase
HN015_RS09035	ENOG4108U05	Transcriptional regulator
HN015_RS09055	ENOG4107TXC	Transcriptional regulator
HN015_RS09060	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HN015_RS09070	ENOG4105C5Q	Transcriptional regulator
HN015_RS09080	ENOG4105EV1	Ribose uptake protein RbsU
HN015_RS09085	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HN015_RS09095	ENOG4105ETE	Transcriptional regulator (LacI family
HN015_RS09100	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HN015_RS09135	ENOG4105ECR	NmrA family
HN015_RS09160	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HN015_RS09175	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HN015_RS09200	ENOG4105BZU	Histidine kinase
HN015_RS09205	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN015_RS09210	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HN015_RS09225	ENOG4105C3G	gtp-binding protein
HN015_RS09230	ENOG4105VDK	protein, conserved in bacteria
HN015_RS09235	ENOG4105FA0	parb-like partition protein
HN015_RS09240	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HN015_RS09250	ENOG4105DU0	nucleoside hydrolase
HN015_RS09265	ENOG4105K4H	Nlp p60 protein
HN015_RS09275	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HN015_RS09280	ENOG4108S01	response regulator
HN015_RS09285	ENOG4105BZU	Histidine kinase
HN015_RS09290	ENOG4108KYE	ABC-2 type transporter
HN015_RS09300	ENOG4107T5V	SNARE associated Golgi
HN015_RS09315	ENOG4105EXC	Acyl-transferase
HN015_RS09320	ENOG4108URH	decarboxylase
HN015_RS09330	ENOG4105C19	ABC transporter
HN015_RS09345	ENOG4105DZW	Dipeptidase
HN015_RS09350	ENOG4105BZU	Histidine kinase
HN015_RS09365	ENOG4105DSG	hydrolase family 43
HN015_RS09370	ENOG4105CT4	transporter
HN015_RS09380	ENOG4105CMG	Carbohydrate kinase
HN015_RS09385	ENOG4105C93	Xylose Isomerase
HN015_RS09395	ENOG4107QNK	)-transporter
HN015_RS09400	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HN015_RS09415	ENOG4105CE4	GlcNAc 6-P deacetylase
HN015_RS09420	ENOG4105E70	isomerase
HN015_RS09430	ENOG4105F3R	pts system mannose fructose sorbose family iid
HN015_RS09440	ENOG4108UZY	PTS System
HN015_RS09470	ENOG410807C	QueT transporter
HN015_RS09475	ENOG4105CIS	alcohol dehydrogenase
HN015_RS09500	ENOG4105DF9	Lipoate-protein, ligase
HN015_RS09505	ENOG4105CK1	PTS System
HN015_RS09510	ENOG4105CS2	ec 3.2.1.21
HN015_RS09515	ENOG4108TZY	GntR Family Transcriptional Regulator
HN015_RS09525	ENOG4105ECB	domain protein
HN015_RS09525	ENOG4105ECB	domain protein
HN015_RS09530	ENOG4107YCR	Transcriptional regulator, ARSR family
HN015_RS09550	ENOG4107KJX	Transcriptional regulator
HN015_RS09565	ENOG4105DY9	regulatoR
HN015_RS09595	ENOG4105CMG	Carbohydrate kinase
HN015_RS09600	ENOG4105C5I	Dehydrogenase
HN015_RS09610	ENOG4105D2H	Uronic isomerase
HN015_RS09620	ENOG4105CT4	transporter
HN015_RS09625	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HN015_RS09630	ENOG4105C0H	protease
HN015_RS09635	ENOG4105Q2H	domain protein
HN015_RS09655	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN015_RS09670	ENOG4105CPC	Aldo Keto reductase
HN015_RS09695	ENOG4105DU0	nucleoside hydrolase
HN015_RS09710	ENOG4107414	GntR family transcriptional regulator
HN015_RS09720	ENOG4105DQ4	alcohol dehydrogenase
HN015_RS09725	ENOG41082BM	Transcriptional regulator, arsr family
HN015_RS09775	ENOG4105CK1	PTS System
HN015_RS09780	ENOG4105CK1	PTS System
HN015_RS09785	ENOG4105ETE	Transcriptional regulator (LacI family
HN015_RS09800	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HN015_RS09810	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HN015_RS09830	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HN015_RS09850	ENOG4105WD1	Membrane
HN015_RS09855	ENOG4105CS2	ec 3.2.1.21
HN015_RS09865	ENOG4105CID	antiterminator
HN015_RS09870	ENOG4105CS2	ec 3.2.1.21
HN015_RS09885	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HN015_RS09890	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HN015_RS09895	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HN015_RS09910	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HN015_RS09920	ENOG4105DFD	Na H antiporter
HN015_RS09925	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HN015_RS09930	ENOG4105K59	histidine triad (HIT) protein
HN015_RS09935	ENOG4105C3F	Signal peptidase i
HN015_RS09940	ENOG4105CK1	PTS System
HN015_RS09955	ENOG4107QSE	Dipeptidase
HN015_RS09965	ENOG4105D1Q	UPF0246 protein
HN015_RS09970	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HN015_RS09975	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HN015_RS09980	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HN015_RS09985	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HN015_RS09990	ENOG4105VG0	50S ribosomal protein l34