locus-tag	class	description
T256_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
T256_RS00010	COG0592	DNA-directed DNA polymerase activity
T256_RS00015	COG2501	S4 domain
T256_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
T256_RS00025	COG0187	DNA topoisomerase II activity
T256_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
T256_RS00040	COG0629	single-stranded DNA binding
T256_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
T256_RS00055	COG0359	binds to the 23S rRNA
T256_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
T256_RS00065	COG2814	Major facilitator Superfamily
T256_RS00080	COG0488	(ABC) transporter
T256_RS00095	COG1136	(ABC) transporter
T256_RS00115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
T256_RS00120	COG1733	regulation of RNA biosynthetic process
T256_RS00125	COG0656	L-ascorbic acid biosynthetic process
T256_RS00135	COG0431	NADPH-dependent FMN reductase
T256_RS00140	COG0640	Transcriptional regulator
T256_RS00160	COG2076	Multidrug Resistance protein
T256_RS00170	COG0446	pyridine nucleotide-disulphide oxidoreductase
T256_RS00175	COG2200	EAL domain
T256_RS00185	COG1272	protein, Hemolysin III
T256_RS00195	COG1301	dicarboxylic acid transport
T256_RS00200	COG0584	glycerophosphoryl diester phosphodiesterase
T256_RS00225	COG1914	H( )-stimulated, divalent metal cation uptake system
T256_RS00235	COG1597	lipid kinase activity
T256_RS00240	COG0583	DNA-binding transcription factor activity
T256_RS00245	COG0110	maltose O-acetyltransferase activity
T256_RS00250	COG4221	oxidoreductase activity
T256_RS00255	COG0656	L-ascorbic acid biosynthetic process
T256_RS00265	COG1131	(ABC) transporter
T256_RS00270	COG1725	Transcriptional regulator
T256_RS00305	COG0667	Aldo Keto reductase
T256_RS00310	COG0653	protein targeting
T256_RS00325	COG1073	alpha beta
T256_RS00370	COG1028	Short-chain dehydrogenase reductase Sdr
T256_RS00380	COG0656	L-ascorbic acid biosynthetic process
T256_RS00385	COG1063	alcohol dehydrogenase
T256_RS00405	COG2217	Heavy metal translocating P-type atpase
T256_RS00430	COG0673	inositol 2-dehydrogenase activity
T256_RS00435	COG0673	inositol 2-dehydrogenase activity
T256_RS00455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
T256_RS00455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
T256_RS00465	COG0110	maltose O-acetyltransferase activity
T256_RS00560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
T256_RS00585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
T256_RS00600	COG1215	transferase activity, transferring glycosyl groups
T256_RS00605	COG2723	6-phospho-beta-galactosidase activity
T256_RS00630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
T256_RS00635	COG0667	Aldo Keto reductase
T256_RS00640	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
T256_RS00700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
T256_RS00710	COG1388	LysM domain
T256_RS00710	COG4932	domain protein
T256_RS00715	COG2814	Major facilitator Superfamily
T256_RS00720	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
T256_RS00725	COG0436	Aminotransferase
T256_RS00730	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
T256_RS00735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
T256_RS00740	COG1473	amidohydrolase
T256_RS00745	COG2171	N-acyltransferase activity
T256_RS00755	COG0527	aspartate kinase activity
T256_RS00760	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
T256_RS00770	COG1737	Transcriptional regulator
T256_RS00780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
T256_RS00780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
T256_RS00780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
T256_RS00785	COG3684	Belongs to the aldolase LacD family
T256_RS00790	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
T256_RS00800	COG1028	Short-chain dehydrogenase reductase Sdr
T256_RS00815	COG1285	pathogenesis
T256_RS00830	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
T256_RS00840	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
T256_RS00855	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
T256_RS00870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
T256_RS00875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
T256_RS00885	COG1609	Transcriptional regulator
T256_RS00890	COG2188	Transcriptional regulator
T256_RS00925	COG2160	L-arabinose isomerase activity
T256_RS00940	COG1297	OPT oligopeptide transporter protein
T256_RS00965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
T256_RS00985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
T256_RS00990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
T256_RS00995	COG3711	transcriptional antiterminator
T256_RS01000	COG1263	PTS System
T256_RS01000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
T256_RS01000	COG2190	(PTS) system
T256_RS01005	COG2723	6-phospho-beta-galactosidase activity
T256_RS01020	COG1846	Transcriptional regulator
T256_RS01020	COG1940	carbohydrate kinase activity
T256_RS01025	COG2115	Belongs to the xylose isomerase family
T256_RS01035	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
T256_RS01040	COG0531	amino acid
T256_RS01045	COG2957	Belongs to the agmatine deiminase family
T256_RS01065	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
T256_RS01065	COG3933	PFAM sigma-54 factor interaction domain-containing protein
T256_RS01080	COG3715	PTS system
T256_RS01085	COG3716	PTS system mannose fructose sorbose family IID component
T256_RS01090	COG2222	sugar isomerase
T256_RS01100	COG1609	Transcriptional regulator
T256_RS01105	COG2017	converts alpha-aldose to the beta-anomer
T256_RS01110	COG2211	Major facilitator Superfamily
T256_RS01110	COG2190	(PTS) system
T256_RS01125	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
T256_RS01130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
T256_RS01135	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
T256_RS01140	COG0114	fumarate hydratase activity
T256_RS01155	COG0477	Major facilitator Superfamily
T256_RS01160	COG1827	regulation of RNA biosynthetic process
T256_RS01165	COG1442	glycosyl transferase family 8
T256_RS01190	COG2017	converts alpha-aldose to the beta-anomer
T256_RS01195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
T256_RS01200	COG0697	spore germination
T256_RS01205	COG0438	transferase activity, transferring glycosyl groups
T256_RS01225	COG0351	phosphomethylpyrimidine kinase
T256_RS01240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
T256_RS01260	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
T256_RS01290	COG0402	S-adenosylhomocysteine deaminase activity
T256_RS01295	COG1174	glycine betaine transport
T256_RS01300	COG1125	glycine betaine transport
T256_RS01300	COG0517	IMP dehydrogenase activity
T256_RS01305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
T256_RS01315	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
T256_RS01325	COG1811	Na channel or pump
T256_RS01335	COG3321	synthase
T256_RS01335	COG0604	alcohol dehydrogenase
T256_RS01345	COG3973	AAA domain
T256_RS01370	COG1983	PspC domain protein
T256_RS01380	COG1801	Protein of unknown function DUF72
T256_RS01385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
T256_RS01385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
T256_RS01390	COG0084	hydrolase, TatD family'
T256_RS01400	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
T256_RS01405	COG4466	Protein conserved in bacteria
T256_RS01410	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
T256_RS01430	COG0477	Major facilitator Superfamily
T256_RS01440	COG3842	ATPase activity
T256_RS01445	COG4120	Belongs to the binding-protein-dependent transport system permease family
T256_RS01455	COG2188	Transcriptional regulator
T256_RS01460	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
T256_RS01465	COG1447	Phosphotransferase system cellobiose-specific component IIA
T256_RS01470	COG2723	6-phospho-beta-galactosidase activity
T256_RS01480	COG0446	pyridine nucleotide-disulphide oxidoreductase
T256_RS01490	COG1573	uracil-dna glycosylase
T256_RS01500	COG0803	Belongs to the bacterial solute-binding protein 9 family
T256_RS01505	COG1121	(ABC) transporter
T256_RS01515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
T256_RS01520	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
T256_RS01530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
T256_RS01550	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
T256_RS01555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
T256_RS01565	COG3590	peptidase
T256_RS01570	COG2252	PERMEase
T256_RS01595	COG2855	membrane
T256_RS01610	COG0561	phosphatase activity
T256_RS01615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
T256_RS01620	COG0540	Belongs to the ATCase OTCase family
T256_RS01625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
T256_RS01630	COG0505	Belongs to the CarA family
T256_RS01635	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
T256_RS01640	COG0167	dihydroorotate dehydrogenase activity
T256_RS01650	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
T256_RS01665	COG1215	transferase activity, transferring glycosyl groups
T256_RS01690	COG1309	transcriptional regulator
T256_RS01695	COG1033	growth of symbiont in host cell
T256_RS01695	COG2409	Drug exporters of the RND superfamily
T256_RS01700	COG2910	NAD(P)H-binding
T256_RS01710	COG1116	anion transmembrane transporter activity
T256_RS01720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
T256_RS01730	COG0363	glucosamine-6-phosphate deaminase activity
T256_RS01735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
T256_RS01740	COG0280	phosphate acetyltransferase
T256_RS01745	COG0735	belongs to the Fur family
T256_RS01755	COG1295	ribonuclease BN
T256_RS01765	COG2365	Tyrosine phosphatase family
T256_RS01770	COG2365	Tyrosine phosphatase family
T256_RS01780	COG0561	phosphatase activity
T256_RS01785	COG1253	flavin adenine dinucleotide binding
T256_RS01790	COG4989	oxidoreductase activity
T256_RS01810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
T256_RS01815	COG2188	Transcriptional regulator
T256_RS01820	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
T256_RS01825	COG0564	pseudouridine synthase activity
T256_RS01835	COG2084	Dehydrogenase
T256_RS01845	COG1376	ErfK ybiS ycfS ynhG family protein
T256_RS01855	COG0586	Pfam SNARE associated Golgi protein
T256_RS01875	COG0025	NhaP-type Na H and K H
T256_RS01885	COG0492	ferredoxin-NADP+ reductase activity
T256_RS01890	COG1368	sulfuric ester hydrolase activity
T256_RS01915	COG0861	Integral membrane protein TerC family
T256_RS01920	COG3118	belongs to the thioredoxin family
T256_RS01940	COG0488	(ABC) transporter
T256_RS01945	COG0656	L-ascorbic acid biosynthetic process
T256_RS01950	COG2267	carboxylic ester hydrolase activity
T256_RS01955	COG2936	dipeptidyl-peptidase activity
T256_RS01965	COG0531	amino acid
T256_RS01975	COG0194	GDP metabolic process
T256_RS01980	COG0735	belongs to the Fur family
T256_RS01995	COG1126	abc transporter atp-binding protein
T256_RS02000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
T256_RS02005	COG0765	amino acid transport
T256_RS02010	COG0765	amino acid transport
T256_RS02025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
T256_RS02030	COG4166	transmembrane transport
T256_RS02035	COG0601	transmembrane transport
T256_RS02040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
T256_RS02045	COG0444	Belongs to the ABC transporter superfamily
T256_RS02050	COG4608	Belongs to the ABC transporter superfamily
T256_RS02055	COG0588	phosphoglycerate mutase activity
T256_RS02060	COG0531	amino acid
T256_RS02065	COG0588	phosphoglycerate mutase activity
T256_RS02070	COG3973	AAA domain
T256_RS02075	COG0028	Belongs to the TPP enzyme family
T256_RS02085	COG1072	(Pantothenic acid kinase))
T256_RS02095	COG2217	Heavy metal translocating P-type atpase
T256_RS02110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
T256_RS02110	COG0519	Catalyzes the synthesis of GMP from XMP
T256_RS02130	COG2814	Major facilitator Superfamily
T256_RS02135	COG0308	aminopeptidase N
T256_RS02145	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
T256_RS02150	COG1518	maintenance of DNA repeat elements
T256_RS02170	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
T256_RS02175	COG0459	protein refolding
T256_RS02180	COG0531	amino acid
T256_RS02185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
T256_RS02190	COG1739	Uncharacterized protein family UPF0029
T256_RS02195	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
T256_RS02200	COG1040	competence protein
T256_RS02210	COG0653	protein targeting
T256_RS02215	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
T256_RS02220	COG0745	RESPONSE REGULATOR receiver
T256_RS02225	COG5002	protein histidine kinase activity
T256_RS02235	COG0573	inorganic phosphate transmembrane transporter activity
T256_RS02240	COG0581	inorganic phosphate transmembrane transporter activity
T256_RS02250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
T256_RS02255	COG0704	Plays a role in the regulation of phosphate uptake
T256_RS02265	COG1950	PFAM Membrane protein of
T256_RS02270	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
T256_RS02275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
T256_RS02280	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
T256_RS02285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
T256_RS02290	COG0492	ferredoxin-NADP+ reductase activity
T256_RS02295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
T256_RS02305	COG0556	nucleotide-excision repair
T256_RS02310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
T256_RS02315	COG1660	Displays ATPase and GTPase activities
T256_RS02320	COG0391	Required for morphogenesis under gluconeogenic growth conditions
T256_RS02325	COG1481	regulation of sporulation
T256_RS02330	COG1388	LysM domain
T256_RS02330	COG1705	Flagellar rod assembly protein muramidase FlgJ
T256_RS02340	COG0740	serine-type endopeptidase activity
T256_RS02425	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
T256_RS02620	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
T256_RS02625	COG2390	Transcriptional regulator
T256_RS02635	COG0126	phosphoglycerate kinase activity
T256_RS02640	COG0149	triose-phosphate isomerase activity
T256_RS02645	COG0148	phosphopyruvate hydratase activity
T256_RS02650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
T256_RS02655	COG0557	exoribonuclease II activity
T256_RS02660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
T256_RS02675	COG0561	phosphatase activity
T256_RS02680	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
T256_RS02685	COG0802	atpase or kinase
T256_RS02705	COG0812	UDP-N-acetylmuramate dehydrogenase activity
T256_RS02710	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
T256_RS02720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
T256_RS02725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
T256_RS02755	COG1328	CTP reductase activity
T256_RS02765	COG0396	ATPase activity
T256_RS02770	COG0719	Fe-S assembly protein
T256_RS02775	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
T256_RS02780	COG0822	iron-sulfur transferase activity
T256_RS02785	COG0719	Fe-S assembly protein
T256_RS02790	COG3479	Phenolic acid decarboxylase
T256_RS02795	COG1695	Transcriptional regulator
T256_RS02820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
T256_RS02820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
T256_RS02835	COG4690	dipeptidase activity
T256_RS02860	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
T256_RS02865	COG2252	PERMEase
T256_RS02870	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
T256_RS02900	COG3475	LICD family
T256_RS02910	COG4221	oxidoreductase activity
T256_RS02915	COG0789	Transcriptional regulator
T256_RS02925	COG2095	MarC family integral membrane protein
T256_RS02945	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
T256_RS02950	COG0351	phosphomethylpyrimidine kinase
T256_RS02955	COG0352	thiamine-phosphate diphosphorylase activity
T256_RS02960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
T256_RS02965	COG0514	ATP-dependent DNA helicase (RecQ)
T256_RS02985	COG0489	protein tyrosine kinase activity
T256_RS02990	COG4464	protein tyrosine phosphatase activity
T256_RS02995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
T256_RS03005	COG1442	glycosyl transferase family 8
T256_RS03005	COG1216	Glycosyl transferase, family 2
T256_RS03010	COG0438	transferase activity, transferring glycosyl groups
T256_RS03015	COG0438	transferase activity, transferring glycosyl groups
T256_RS03025	COG0562	UDP-galactopyranose mutase
T256_RS03050	COG0531	amino acid
T256_RS03060	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
T256_RS03075	COG0673	inositol 2-dehydrogenase activity
T256_RS03080	COG0513	Belongs to the DEAD box helicase family
T256_RS03085	COG1316	TRANSCRIPTIONal
T256_RS03105	COG0516	GMP reductase activity
T256_RS03110	COG2309	aminopeptidase activity
T256_RS03115	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
T256_RS03120	COG0716	FMN binding
T256_RS03125	COG2137	regulation of response to DNA damage stimulus
T256_RS03130	COG3557	Belongs to the UPF0374 family
T256_RS03135	COG0628	permease
T256_RS03140	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
T256_RS03145	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
T256_RS03150	COG1368	sulfuric ester hydrolase activity
T256_RS03155	COG0730	response to heat
T256_RS03165	COG0542	response to heat
T256_RS03185	COG0596	Alpha beta hydrolase
T256_RS03190	COG0438	transferase activity, transferring glycosyl groups
T256_RS03195	COG0438	transferase activity, transferring glycosyl groups
T256_RS03315	COG0028	Belongs to the TPP enzyme family
T256_RS03325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
T256_RS03330	COG2814	Major facilitator Superfamily
T256_RS03335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
T256_RS03340	COG0671	phosphoesterase, PA-phosphatase related
T256_RS03345	COG0495	leucyl-tRNA aminoacylation
T256_RS03350	COG2244	polysaccharide biosynthetic process
T256_RS03355	COG1187	pseudouridine synthase activity
T256_RS03360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
T256_RS03365	COG0589	response to stress
T256_RS03370	COG1428	Deoxynucleoside kinase
T256_RS03415	COG0367	asparagine synthase
T256_RS03440	COG0531	amino acid
T256_RS03455	COG0561	phosphatase activity
T256_RS03460	COG0667	Aldo Keto reductase
T256_RS03465	COG0018	arginyl-trna synthetase
T256_RS03475	COG1438	arginine binding
T256_RS03480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
T256_RS03485	COG3679	Belongs to the UPF0342 family
T256_RS03490	COG0420	3'-5' exonuclease activity
T256_RS03495	COG4717	serine-type aminopeptidase activity
T256_RS03500	COG3481	metal-dependent phosphohydrolase, HD sub domain
T256_RS03505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
T256_RS03515	COG0537	adenosine 5'-monophosphoramidase activity
T256_RS03520	COG1131	(ABC) transporter
T256_RS03525	COG4473	ABC transporter
T256_RS03530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
T256_RS03540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
T256_RS03545	COG1674	ftsk spoiiie
T256_RS03550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
T256_RS03555	COG0670	Belongs to the BI1 family
T256_RS03560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
T256_RS03560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
T256_RS03565	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
T256_RS03570	COG0237	dephospho-CoA kinase activity
T256_RS03575	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
T256_RS03585	COG1484	DNA-dependent DNA replication
T256_RS03590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
T256_RS03595	COG3275	phosphorelay sensor kinase activity
T256_RS03600	COG3279	Response regulator of the LytR AlgR family
T256_RS03610	COG1346	cytolysis
T256_RS03615	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
T256_RS03620	COG0291	Belongs to the bacterial ribosomal protein bL35 family
T256_RS03625	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
T256_RS03640	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
T256_RS03645	COG1534	Rna-binding protein
T256_RS03650	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
T256_RS03655	COG1713	HD superfamily hydrolase involved in NAD metabolism
T256_RS03660	COG0799	negative regulation of ribosome biogenesis
T256_RS03665	COG2226	methyltransferase
T256_RS03670	COG1323	Belongs to the UPF0348 family
T256_RS03675	COG1399	metal-binding, possibly nucleic acid-binding protein
T256_RS03680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
T256_RS03685	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
T256_RS03690	COG0745	RESPONSE REGULATOR receiver
T256_RS03695	COG5002	protein histidine kinase activity
T256_RS03700	COG0706	membrane insertase activity
T256_RS03705	COG1254	Belongs to the acylphosphatase family
T256_RS03710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
T256_RS03720	COG1733	regulation of RNA biosynthetic process
T256_RS03725	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
T256_RS03730	COG0072	phenylalanine-tRNA ligase activity
T256_RS03730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
T256_RS03735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
T256_RS03740	COG0572	uridine kinase
T256_RS03745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
T256_RS03755	COG0768	penicillin binding
T256_RS03760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
T256_RS03765	COG0705	Rhomboid family
T256_RS03775	COG1940	carbohydrate kinase activity
T256_RS03780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
T256_RS03785	COG0584	glycerophosphoryl diester phosphodiesterase
T256_RS03790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
T256_RS03795	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
T256_RS03800	COG0789	Transcriptional regulator
T256_RS03850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
T256_RS03860	COG0211	Belongs to the bacterial ribosomal protein bL27 family
T256_RS03865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
T256_RS03870	COG1302	Protein conserved in bacteria
T256_RS03875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
T256_RS03880	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
T256_RS03885	COG1570	exodeoxyribonuclease VII activity
T256_RS03890	COG1722	exodeoxyribonuclease VII activity
T256_RS03900	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
T256_RS03905	COG1438	arginine binding
T256_RS03910	COG0497	DNA recombination
T256_RS03920	COG0194	GDP metabolic process
T256_RS03925	COG1758	RNA polymerase activity
T256_RS03930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
T256_RS03935	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
T256_RS03940	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
T256_RS03945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
T256_RS03945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
T256_RS03950	COG0631	protein serine/threonine phosphatase activity
T256_RS03960	COG1162	GTPase activity
T256_RS03965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
T256_RS03970	COG1564	THIamine pyrophosphokinase
T256_RS03975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
T256_RS03980	COG1302	Protein conserved in bacteria
T256_RS03990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
T256_RS03995	COG0416	fatty acid biosynthetic process
T256_RS04000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
T256_RS04005	COG0571	ribonuclease III activity
T256_RS04010	COG1196	nuclear chromosome segregation
T256_RS04015	COG0552	protein localization to endoplasmic reticulum
T256_RS04020	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
T256_RS04025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
T256_RS04030	COG0228	four-way junction DNA binding
T256_RS04035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
T256_RS04040	COG0336	Belongs to the RNA methyltransferase TrmD family
T256_RS04045	COG0335	large ribosomal subunit rRNA binding
T256_RS04050	COG0393	Putative heavy-metal-binding
T256_RS04060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
T256_RS04065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
T256_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
T256_RS04085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
T256_RS04090	COG0511	ligase activity, forming carbon-carbon bonds
T256_RS04100	COG0439	Biotin carboxylase
T256_RS04105	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
T256_RS04110	COG0825	malonyl-CoA metabolic process
T256_RS04115	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
T256_RS04120	COG1113	amino acid transport
T256_RS04125	COG3425	synthase
T256_RS04135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
T256_RS04140	COG4224	UPF0291 protein
T256_RS04145	COG3763	UPF0154 protein
T256_RS04150	COG0204	Acyl-transferase
T256_RS04155	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
T256_RS04160	COG2827	Endonuclease containing a URI domain
T256_RS04170	COG0052	Belongs to the universal ribosomal protein uS2 family
T256_RS04175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
T256_RS04180	COG0528	UMP kinase activity
T256_RS04185	COG0233	cytoplasmic translational termination
T256_RS04190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
T256_RS04195	COG4589	Belongs to the CDS family
T256_RS04200	COG0750	zinc metalloprotease
T256_RS04205	COG0442	prolyl-tRNA aminoacylation
T256_RS04210	COG2176	DNA-directed DNA polymerase activity
T256_RS04215	COG0779	Required for maturation of 30S ribosomal subunits
T256_RS04220	COG0195	Participates in both transcription termination and antitermination
T256_RS04225	COG2740	Nucleic-acid-binding protein implicated in transcription termination
T256_RS04235	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
T256_RS04240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
T256_RS04245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
T256_RS04250	COG0196	riboflavin kinase activity
T256_RS04255	COG1420	regulation of RNA biosynthetic process
T256_RS04260	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
T256_RS04265	COG0443	Heat shock 70 kDa protein
T256_RS04270	COG0484	heat shock protein binding
T256_RS04275	COG2155	Conserved Protein
T256_RS04295	COG1028	Short-chain dehydrogenase reductase Sdr
T256_RS04305	COG2261	transglycosylase associated protein
T256_RS04330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
T256_RS04340	COG1942	4-Oxalocrotonate Tautomerase
T256_RS04345	COG0561	phosphatase activity
T256_RS04350	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
T256_RS04350	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
T256_RS04380	COG1304	FMN binding
T256_RS04390	COG1304	FMN binding
T256_RS04420	COG3935	DnaD domain protein
T256_RS04425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
T256_RS04430	COG3331	DNA recombination
T256_RS04435	COG4474	Belongs to the UPF0398 family
T256_RS04440	COG3599	regulation of cell shape
T256_RS04445	COG0116	Belongs to the methyltransferase superfamily
T256_RS04460	COG2759	Belongs to the formate--tetrahydrofolate ligase family
T256_RS04465	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
T256_RS04470	COG0564	pseudouridine synthase activity
T256_RS04475	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
T256_RS04490	COG1293	RNA-binding protein homologous to eukaryotic snRNP
T256_RS04500	COG1307	EDD domain protein, DegV family
T256_RS04505	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
T256_RS04510	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
T256_RS04535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
T256_RS04540	COG1929	Belongs to the glycerate kinase type-1 family
T256_RS04545	COG1227	inorganic diphosphatase activity
T256_RS04550	COG0583	DNA-binding transcription factor activity
T256_RS04560	COG0187	DNA topoisomerase II activity
T256_RS04575	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
T256_RS04580	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
T256_RS04585	COG4974	Belongs to the 'phage' integrase family
T256_RS04590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
T256_RS04595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
T256_RS04610	COG1609	Transcriptional regulator
T256_RS04615	COG0758	DNA mediated transformation
T256_RS04620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
T256_RS04925	COG0582	viral genome integration into host DNA
T256_RS04960	COG0367	asparagine synthase
T256_RS04975	COG0583	DNA-binding transcription factor activity
T256_RS05005	COG0105	UTP biosynthetic process
T256_RS05010	COG0519	Catalyzes the synthesis of GMP from XMP
T256_RS05015	COG0531	amino acid
T256_RS05020	COG1393	Belongs to the ArsC family
T256_RS05025	COG1757	Na H antiporter
T256_RS05030	COG3409	Peptidoglycan-binding domain 1 protein
T256_RS05030	COG0793	Belongs to the peptidase S41A family
T256_RS05035	COG4479	Belongs to the UPF0346 family
T256_RS05045	COG2755	lipolytic protein G-D-S-L family
T256_RS05050	COG1307	EDD domain protein, DegV family
T256_RS05055	COG1126	abc transporter atp-binding protein
T256_RS05060	COG0765	amino acid transport
T256_RS05065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
T256_RS05070	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
T256_RS05075	COG0488	(ABC) transporter
T256_RS05080	COG0617	tRNA 3'-terminal CCA addition
T256_RS05085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
T256_RS05100	COG0457	Tetratricopeptide repeat
T256_RS05115	COG0539	negative regulation of cytoplasmic translation
T256_RS05120	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
T256_RS05130	COG0514	ATP-dependent DNA helicase (RecQ)
T256_RS05140	COG1187	pseudouridine synthase activity
T256_RS05145	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
T256_RS05150	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
T256_RS05165	COG2996	Protein conserved in bacteria
T256_RS05170	COG2707	UPF0756 membrane protein
T256_RS05185	COG0205	6-phosphofructokinase activity
T256_RS05190	COG0587	DNA-directed DNA polymerase activity
T256_RS05200	COG0542	response to heat
T256_RS05205	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
T256_RS05210	COG2384	SAM-dependent methyltransferase
T256_RS05215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
T256_RS05220	COG0358	DNA primase activity
T256_RS05225	COG0751	glycine-tRNA ligase activity
T256_RS05230	COG0752	glycyl-tRNA synthetase alpha subunit
T256_RS05235	COG1381	Involved in DNA repair and RecF pathway recombination
T256_RS05240	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
T256_RS05250	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
T256_RS05255	COG1702	phosphate starvation-inducible protein PhoH
T256_RS05260	COG1610	YqeY-like protein
T256_RS05265	COG0828	Belongs to the bacterial ribosomal protein bS21 family
T256_RS05270	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
T256_RS05275	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
T256_RS05290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
T256_RS05295	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
T256_RS05300	COG0124	histidyl-tRNA synthetase
T256_RS05310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
T256_RS05310	COG0131	Imidazoleglycerol-phosphate dehydratase
T256_RS05315	COG1490	D-aminoacyl-tRNA deacylase activity
T256_RS05320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
T256_RS05330	COG1385	rRNA (uridine-N3-)-methyltransferase activity
T256_RS05335	COG2264	protein methyltransferase activity
T256_RS05340	COG2233	PERMEase
T256_RS05350	COG0697	spore germination
T256_RS05365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
T256_RS05370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
T256_RS05370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
T256_RS05375	COG0300	oxidoreductase activity
T256_RS05380	COG1234	tRNA 3'-trailer cleavage
T256_RS05390	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
T256_RS05395	COG0322	excinuclease ABC activity
T256_RS05400	COG1126	abc transporter atp-binding protein
T256_RS05405	COG0765	amino acid transport
T256_RS05415	COG0218	Necessary for normal cell division and for the maintenance of normal septation
T256_RS05420	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
T256_RS05425	COG0544	peptidyl-prolyl cis-trans isomerase activity
T256_RS05430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
T256_RS05445	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
T256_RS05450	COG0268	Binds directly to 16S ribosomal RNA
T256_RS05455	COG1466	dna polymerase III delta subunit
T256_RS05460	COG2333	competence protein COMEC
T256_RS05460	COG0658	competence protein
T256_RS05465	COG2131	deaminase
T256_RS05470	COG1555	photosystem II stabilization
T256_RS05470	COG1596	polysaccharide export
T256_RS05475	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
T256_RS05480	COG0742	ribosomal rna small subunit methyltransferase
T256_RS05485	COG4471	UPF0298 protein
T256_RS05490	COG0772	Belongs to the SEDS family
T256_RS05495	COG1217	gtp-binding protein TYPA
T256_RS05500	COG0483	inositol monophosphate 1-phosphatase activity
T256_RS05510	COG0242	peptide deformylase activity
T256_RS05520	COG5503	Protein of unknown function (DUF1447)
T256_RS05535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
T256_RS05535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
T256_RS05535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
T256_RS05540	COG1105	Belongs to the carbohydrate kinase PfkB family
T256_RS05545	COG1349	DNA-binding transcription factor activity
T256_RS05550	COG0628	permease
T256_RS05555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
T256_RS05560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
T256_RS05575	COG0482	sulfurtransferase activity
T256_RS05585	COG1104	cysteine desulfurase activity
T256_RS05590	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
T256_RS05600	COG0494	nUDIX hydrolase
T256_RS05610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
T256_RS05615	COG3599	regulation of cell shape
T256_RS05630	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
T256_RS05635	COG0849	cell division
T256_RS05640	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
T256_RS05645	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
T256_RS05650	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
T256_RS05655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
T256_RS05660	COG0768	penicillin binding
T256_RS05670	COG0275	rRNA processing
T256_RS05675	COG2001	Belongs to the MraZ family
T256_RS05680	COG1674	ftsk spoiiie
T256_RS05690	COG0628	permease
T256_RS05700	COG2706	6-phosphogluconolactonase activity
T256_RS05705	COG3142	Participates in the control of copper homeostasis
T256_RS05710	COG2239	Acts as a magnesium transporter
T256_RS05715	COG0564	pseudouridine synthase activity
T256_RS05720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
T256_RS05725	COG2357	RelA SpoT domain protein
T256_RS05740	COG4862	establishment of competence for transformation
T256_RS05745	COG1393	Belongs to the ArsC family
T256_RS05750	COG1234	tRNA 3'-trailer cleavage
T256_RS05835	COG0586	Pfam SNARE associated Golgi protein
T256_RS05845	COG0647	UMP catabolic process
T256_RS05850	COG4470	Protein conserved in bacteria
T256_RS05860	COG1113	amino acid transport
T256_RS05865	COG0827	DNA restriction-modification system
T256_RS05890	COG4537	Required for transformation and DNA binding
T256_RS05895	COG1459	type II secretion system
T256_RS05900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
T256_RS05910	COG0217	transcriptional regulatory protein
T256_RS05925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
T256_RS05930	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
T256_RS05935	COG1335	isochorismatase
T256_RS05940	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
T256_RS05945	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
T256_RS05955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
T256_RS05960	COG1609	Transcriptional regulator
T256_RS05965	COG0006	proline dipeptidase activity
T256_RS05970	COG0028	Belongs to the TPP enzyme family
T256_RS05985	COG0668	transmembrane transport
T256_RS05990	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
T256_RS05995	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
T256_RS06000	COG3118	belongs to the thioredoxin family
T256_RS06005	COG1193	negative regulation of DNA recombination
T256_RS06010	COG3906	Belongs to the UPF0473 family
T256_RS06015	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
T256_RS06020	COG4472	Bacterial protein of unknown function (DUF965)
T256_RS06025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
T256_RS06030	COG0513	Belongs to the DEAD box helicase family
T256_RS06035	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
T256_RS06040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
T256_RS06045	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
T256_RS06050	COG1862	Preprotein translocase
T256_RS06055	COG0343	queuine tRNA-ribosyltransferase activity
T256_RS06060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
T256_RS06065	COG2255	four-way junction helicase activity
T256_RS06070	COG0632	four-way junction helicase activity
T256_RS06075	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
T256_RS06080	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
T256_RS06085	COG1418	mRNA catabolic process
T256_RS06095	COG1546	Belongs to the CinA family
T256_RS06095	COG1058	Belongs to the CinA family
T256_RS06100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
T256_RS06110	COG0300	oxidoreductase activity
T256_RS06115	COG0612	Peptidase, M16
T256_RS06120	COG0612	Peptidase, M16
T256_RS06125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
T256_RS06130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
T256_RS06135	COG1126	abc transporter atp-binding protein
T256_RS06140	COG0765	amino acid transport
T256_RS06160	COG0285	dihydrofolate synthase activity
T256_RS06165	COG0525	valine-tRNA ligase activity
T256_RS06170	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
T256_RS06175	COG0301	tRNA thio-modification
T256_RS06180	COG1104	cysteine desulfurase activity
T256_RS06185	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
T256_RS06190	COG1956	GAF domain-containing protein
T256_RS06195	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
T256_RS06200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
T256_RS06210	COG0589	response to stress
T256_RS06220	COG1181	Belongs to the D-alanine--D-alanine ligase family
T256_RS06230	COG0531	amino acid
T256_RS06245	COG1131	(ABC) transporter
T256_RS06250	COG1725	Transcriptional regulator
T256_RS06255	COG1464	Belongs to the NlpA lipoprotein family
T256_RS06260	COG2011	ABC-type metal ion transport system permease component
T256_RS06265	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
T256_RS06270	COG0772	Belongs to the SEDS family
T256_RS06280	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
T256_RS06290	COG0355	proton-transporting ATP synthase activity, rotational mechanism
T256_RS06295	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
T256_RS06300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
T256_RS06305	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
T256_RS06310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
T256_RS06315	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
T256_RS06320	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
T256_RS06325	COG0356	it plays a direct role in the translocation of protons across the membrane
T256_RS06340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
T256_RS06345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
T256_RS06350	COG0009	L-threonylcarbamoyladenylate synthase
T256_RS06355	COG2890	protein-(glutamine-N5) methyltransferase activity
T256_RS06360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
T256_RS06365	COG1435	thymidine kinase activity
T256_RS06370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
T256_RS06375	COG3442	glutamine amidotransferase
T256_RS06380	COG1482	cell wall glycoprotein biosynthetic process
T256_RS06385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
T256_RS06390	COG1132	(ABC) transporter
T256_RS06410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
T256_RS06430	COG0330	HflC and HflK could
T256_RS06440	COG0431	NADPH-dependent FMN reductase
T256_RS06440	COG1053	succinate dehydrogenase
T256_RS06440	COG3976	FMN-binding domain protein
T256_RS06445	COG3976	FMN-binding domain protein
T256_RS06445	COG1053	succinate dehydrogenase
T256_RS06445	COG0431	NADPH-dependent FMN reductase
T256_RS06455	COG0166	Belongs to the GPI family
T256_RS06465	COG4975	Glucose uptake
T256_RS06470	COG0191	fructose-bisphosphate aldolase activity
T256_RS06475	COG5002	protein histidine kinase activity
T256_RS06475	COG3850	Histidine kinase
T256_RS06480	COG0745	RESPONSE REGULATOR receiver
T256_RS06490	COG0741	lytic transglycosylase activity
T256_RS06495	COG1247	-acetyltransferase
T256_RS06510	COG2610	gluconate transmembrane transporter activity
T256_RS06520	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
T256_RS06525	COG1737	Transcriptional regulator
T256_RS06550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
T256_RS06555	COG1597	lipid kinase activity
T256_RS06560	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
T256_RS06565	COG0154	amidase activity
T256_RS06575	COG4851	CamS sex pheromone cAM373 precursor
T256_RS06585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
T256_RS06590	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
T256_RS06595	COG1705	Flagellar rod assembly protein muramidase FlgJ
T256_RS06605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
T256_RS06625	COG0783	Belongs to the Dps family
T256_RS06640	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
T256_RS06645	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
T256_RS06660	COG1122	ATPase activity
T256_RS06665	COG1122	ATPase activity
T256_RS06670	COG0203	ribosomal protein L17
T256_RS06675	COG0202	RNA polymerase activity
T256_RS06680	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
T256_RS06685	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
T256_RS06690	COG0257	Belongs to the bacterial ribosomal protein bL36 family
T256_RS06695	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
T256_RS06710	COG0200	Binds to the 23S rRNA
T256_RS06715	COG1841	ribosomal large subunit assembly
T256_RS06720	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
T256_RS06725	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
T256_RS06730	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
T256_RS06735	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
T256_RS06740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
T256_RS06745	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
T256_RS06750	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
T256_RS06755	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
T256_RS06765	COG0255	Belongs to the universal ribosomal protein uL29 family
T256_RS06770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
T256_RS06775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
T256_RS06780	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
T256_RS06785	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
T256_RS06790	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
T256_RS06795	COG0089	rRNA binding
T256_RS06800	COG0088	Forms part of the polypeptide exit tunnel
T256_RS06805	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
T256_RS06810	COG0051	transcription antitermination factor activity, RNA binding
T256_RS06815	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
T256_RS06820	COG0049	tRNA binding
T256_RS06825	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
T256_RS06835	COG1957	nucleoside hydrolase
T256_RS06840	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
T256_RS06845	COG0085	RNA polymerase activity
T256_RS06850	COG0542	response to heat
T256_RS06855	COG4463	regulation of RNA biosynthetic process
T256_RS06890	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
T256_RS06895	COG1428	Deoxynucleoside kinase
T256_RS06900	COG0833	amino acid
T256_RS06910	COG2755	lipolytic protein G-D-S-L family
T256_RS06910	COG0657	acetylesterase activity
T256_RS06915	COG1316	TRANSCRIPTIONal
T256_RS06920	COG1940	carbohydrate kinase activity
T256_RS06935	COG1278	Cold shock
T256_RS06945	COG1418	mRNA catabolic process
T256_RS06950	COG1418	mRNA catabolic process
T256_RS06960	COG0564	pseudouridine synthase activity
T256_RS06980	COG4690	dipeptidase activity
T256_RS06990	COG0151	Belongs to the GarS family
T256_RS06995	COG0138	bifunctional purine biosynthesis protein purh
T256_RS07000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
T256_RS07005	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
T256_RS07010	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
T256_RS07015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
T256_RS07020	COG0047	phosphoribosylformylglycinamidine synthase activity
T256_RS07025	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
T256_RS07030	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
T256_RS07035	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
T256_RS07040	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
T256_RS07045	COG2502	aspartate--ammonia ligase
T256_RS07050	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
T256_RS07060	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
T256_RS07065	COG1214	PFAM Peptidase M22, glycoprotease
T256_RS07065	COG0456	acetyltransferase
T256_RS07070	COG1214	PFAM Peptidase M22, glycoprotease
T256_RS07075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
T256_RS07085	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
T256_RS07090	COG4467	Involved in initiation control of chromosome replication
T256_RS07095	COG0470	DNA polymerase III
T256_RS07100	COG3870	Protein conserved in bacteria
T256_RS07105	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
T256_RS07110	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
T256_RS07115	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
T256_RS07120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
T256_RS07130	COG2813	Specifically methylates the guanine in position
T256_RS07135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
T256_RS07145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
T256_RS07150	COG0222	ribosome binding
T256_RS07155	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
T256_RS07160	COG0081	regulation of translation
T256_RS07165	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
T256_RS07170	COG0250	Participates in transcription elongation, termination and antitermination
T256_RS07180	COG0267	Belongs to the bacterial ribosomal protein bL33 family
T256_RS07190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
T256_RS07195	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
T256_RS07200	COG0215	cysteine-tRNA ligase activity
T256_RS07205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
T256_RS07210	COG4956	integral membrane protein (PIN domain superfamily)
T256_RS07215	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
T256_RS07220	COG0756	dUTP diphosphatase activity
T256_RS07230	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
T256_RS07240	COG1733	regulation of RNA biosynthetic process
T256_RS07245	COG2814	Major facilitator Superfamily
T256_RS07250	COG0588	phosphoglycerate mutase activity
T256_RS07255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
T256_RS07270	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
T256_RS07270	COG3933	PFAM sigma-54 factor interaction domain-containing protein
T256_RS07280	COG3716	PTS system mannose fructose sorbose family IID component
T256_RS07285	COG3715	PTS system
T256_RS07300	COG3091	SprT-like family
T256_RS07305	COG2183	response to ionizing radiation
T256_RS07325	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
T256_RS07335	COG2188	Transcriptional regulator
T256_RS07345	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
T256_RS07365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
T256_RS07370	COG3104	oligopeptide transport
T256_RS07400	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
T256_RS07405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
T256_RS07410	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
T256_RS07425	COG0037	tRNA processing
T256_RS07430	COG1098	S1 RNA binding domain
T256_RS07440	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
T256_RS07445	COG2244	polysaccharide biosynthetic process
T256_RS07450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
T256_RS07455	COG0193	aminoacyl-tRNA hydrolase activity
T256_RS07460	COG0039	L-malate dehydrogenase activity
T256_RS07475	COG2337	Toxic component of a toxin-antitoxin (TA) module
T256_RS07485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
T256_RS07490	COG0736	holo-[acyl-carrier-protein] synthase activity
T256_RS07500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
T256_RS07510	COG0501	Belongs to the peptidase M48B family
T256_RS07515	COG1704	LemA family
T256_RS07520	COG3764	Sortase (surface protein transpeptidase)
T256_RS07530	COG0254	rRNA binding
T256_RS07535	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
T256_RS07540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
T256_RS07545	COG0504	CTP synthase activity
T256_RS07550	COG3343	RNA polymerase activity
T256_RS07560	COG1078	dGTPase activity
T256_RS07610	COG4166	transmembrane transport
T256_RS07620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
T256_RS07625	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
T256_RS07630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
T256_RS07635	COG1696	Membrane protein involved in D-alanine export
T256_RS07640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
T256_RS07650	COG1268	BioY protein
T256_RS07655	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
T256_RS07665	COG2814	Major facilitator Superfamily
T256_RS07675	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
T256_RS07690	COG1134	teichoic acid transport
T256_RS07695	COG1682	transport, permease protein
T256_RS07710	COG0463	Glycosyl transferase, family 2
T256_RS07715	COG2246	polysaccharide biosynthetic process
T256_RS07720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
T256_RS07725	COG0708	Exodeoxyribonuclease III
T256_RS07755	COG0446	pyridine nucleotide-disulphide oxidoreductase
T256_RS07760	COG0667	Aldo Keto reductase
T256_RS07775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
T256_RS07785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
T256_RS07790	COG1288	antiporter activity
T256_RS07805	COG2235	arginine
T256_RS07810	COG0549	Belongs to the carbamate kinase family
T256_RS07815	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
T256_RS07825	COG1164	Oligoendopeptidase f
T256_RS07835	COG2814	Major facilitator Superfamily
T256_RS07845	COG1268	BioY protein
T256_RS07850	COG1854	S-ribosylhomocysteine lyase activity
T256_RS07855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
T256_RS07860	COG0110	maltose O-acetyltransferase activity
T256_RS07865	COG0446	pyridine nucleotide-disulphide oxidoreductase
T256_RS07880	COG0105	UTP biosynthetic process
T256_RS07895	COG0697	spore germination
T256_RS07905	COG0488	(ABC) transporter
T256_RS07910	COG1136	(ABC) transporter
T256_RS07910	COG0577	efflux transmembrane transporter activity
T256_RS07915	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
T256_RS07920	COG1174	glycine betaine transport
T256_RS07945	COG0673	inositol 2-dehydrogenase activity
T256_RS07950	COG1132	(ABC) transporter
T256_RS07955	COG1846	Transcriptional regulator
T256_RS07960	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
T256_RS07965	COG1461	Dihydroxyacetone kinase
T256_RS07970	COG2376	Dihydroxyacetone kinase
T256_RS07975	COG2357	RelA SpoT domain protein
T256_RS07985	COG2249	NAD(P)H dehydrogenase (quinone) activity
T256_RS07995	COG1302	Protein conserved in bacteria
T256_RS08010	COG2261	transglycosylase associated protein
T256_RS08015	COG0561	phosphatase activity
T256_RS08020	COG0284	orotidine-5'-phosphate decarboxylase activity
T256_RS08025	COG0242	peptide deformylase activity
T256_RS08035	COG1846	Transcriptional regulator
T256_RS08040	COG1309	transcriptional regulator
T256_RS08050	COG1131	(ABC) transporter
T256_RS08070	COG0583	DNA-binding transcription factor activity
T256_RS08080	COG2814	Major facilitator Superfamily
T256_RS08090	COG1606	tRNA processing
T256_RS08095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
T256_RS08100	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
T256_RS08105	COG1691	(AIR) carboxylase
T256_RS08110	COG3875	lactate racemase activity
T256_RS08115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
T256_RS08120	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
T256_RS08125	COG4975	Glucose uptake
T256_RS08130	COG1869	D-ribose catabolic process
T256_RS08140	COG1609	Transcriptional regulator
T256_RS08145	COG1914	H( )-stimulated, divalent metal cation uptake system
T256_RS08165	COG0406	alpha-ribazole phosphatase activity
T256_RS08190	COG0588	phosphoglycerate mutase activity
T256_RS08200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
T256_RS08215	COG1686	Belongs to the peptidase S11 family
T256_RS08225	COG0745	RESPONSE REGULATOR receiver
T256_RS08230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
T256_RS08235	COG0517	IMP dehydrogenase activity
T256_RS08235	COG0516	GMP reductase activity
T256_RS08245	COG0012	GTP binding
T256_RS08250	COG4481	Protein conserved in bacteria
T256_RS08255	COG1475	DNA binding
T256_RS08260	COG0357	Ribosomal RNA small subunit methyltransferase G
T256_RS08275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
T256_RS08285	COG0791	NLP P60 protein
T256_RS08295	COG2814	Major facilitator Superfamily
T256_RS08300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
T256_RS08305	COG2197	response regulator
T256_RS08310	COG4585	Histidine kinase
T256_RS08320	COG1131	(ABC) transporter
T256_RS08325	COG0586	Pfam SNARE associated Golgi protein
T256_RS08340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
T256_RS08340	COG2755	lipolytic protein G-D-S-L family
T256_RS08355	COG1136	(ABC) transporter
T256_RS08365	COG3048	D-serine ammonia-lyase activity
T256_RS08420	COG2222	sugar isomerase
T256_RS08425	COG2188	Transcriptional regulator
T256_RS08430	COG3716	PTS system mannose fructose sorbose family IID component
T256_RS08435	COG3715	PTS system
T256_RS08440	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
T256_RS08465	COG4708	membrane
T256_RS08480	COG1959	2 iron, 2 sulfur cluster binding
T256_RS08515	COG0095	Lipoate-protein ligase
T256_RS08520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
T256_RS08525	COG2723	6-phospho-beta-galactosidase activity
T256_RS08530	COG2188	Transcriptional regulator
T256_RS08550	COG1511	domain protein
T256_RS08550	COG1511	domain protein
T256_RS08555	COG0640	Transcriptional regulator
T256_RS08565	COG1307	EDD domain protein, DegV family
T256_RS08585	COG3546	catalase activity
T256_RS08595	COG3706	GGDEF domain
T256_RS08600	COG2814	Major facilitator Superfamily
T256_RS08605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
T256_RS08610	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
T256_RS08630	COG0745	RESPONSE REGULATOR receiver
T256_RS08645	COG0583	DNA-binding transcription factor activity
T256_RS08660	COG0561	phosphatase activity
T256_RS08665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
T256_RS08665	COG1263	PTS System
T256_RS08665	COG2190	(PTS) system
T256_RS08670	COG2188	Transcriptional regulator
T256_RS08675	COG0366	Alpha amylase catalytic
T256_RS08690	COG0025	NhaP-type Na H and K H
T256_RS08700	COG1970	mechanosensitive ion channel activity
T256_RS08705	COG0577	efflux transmembrane transporter activity
T256_RS08705	COG1136	(ABC) transporter
T256_RS08705	COG0577	efflux transmembrane transporter activity
T256_RS08705	COG1136	(ABC) transporter
T256_RS08720	COG1263	PTS System
T256_RS08720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
T256_RS08720	COG2190	(PTS) system
T256_RS08725	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
T256_RS08730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
T256_RS08730	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
T256_RS08740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
T256_RS08740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
T256_RS08745	COG1012	belongs to the aldehyde dehydrogenase family
T256_RS08750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
T256_RS08755	COG1695	Transcriptional regulator
T256_RS08795	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
T256_RS08800	COG1074	ATP-dependent DNA helicase activity
T256_RS08805	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
T256_RS08820	COG0519	Catalyzes the synthesis of GMP from XMP
T256_RS08825	COG2755	lipolytic protein G-D-S-L family
T256_RS08825	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
T256_RS08830	COG1757	Na H antiporter
T256_RS08835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
T256_RS08840	COG0537	adenosine 5'-monophosphoramidase activity
T256_RS08850	COG3022	response to hydroperoxide
T256_RS08855	COG0445	tRNA wobble uridine modification
T256_RS08860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
T256_RS08865	COG0706	membrane insertase activity
T256_RS08870	COG0594	ribonuclease P activity
T256_RS08875	COG0230	Belongs to the bacterial ribosomal protein bL34 family
T256_RS08910	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC