locus-tag	class	description
AQ505_RS00015	COG1629	transport
AQ505_RS00025	COG4771	TonB-dependent receptor
AQ505_RS00035	COG1629	transport
AQ505_RS00035	COG4206	TonB-dependent receptor
AQ505_RS00045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AQ505_RS00060	COG1774	PSP1 C-terminal conserved region
AQ505_RS00065	COG0470	DNA polymerase III
AQ505_RS00070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AQ505_RS00085	COG1705	Flagellar rod assembly protein muramidase FlgJ
AQ505_RS00085	COG1388	LysM domain
AQ505_RS00105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AQ505_RS00110	COG0606	chelatase, subunit chli
AQ505_RS00165	COG0339	signal peptide processing
AQ505_RS00185	COG0326	Molecular chaperone. Has ATPase activity
AQ505_RS00205	COG0612	Peptidase, M16
AQ505_RS00210	COG0242	peptide deformylase activity
AQ505_RS00220	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AQ505_RS00225	COG0489	protein tyrosine kinase activity
AQ505_RS00230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AQ505_RS00235	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AQ505_RS00240	COG0688	phosphatidylethanolamine metabolic process
AQ505_RS00245	COG0335	large ribosomal subunit rRNA binding
AQ505_RS00265	COG0336	Belongs to the RNA methyltransferase TrmD family
AQ505_RS00270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AQ505_RS00275	COG0228	four-way junction DNA binding
AQ505_RS00280	COG0393	Putative heavy-metal-binding
AQ505_RS00285	COG0205	6-phosphofructokinase activity
AQ505_RS00290	COG4232	protein-disulfide reductase activity
AQ505_RS00300	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AQ505_RS00300	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AQ505_RS00305	COG0799	negative regulation of ribosome biogenesis
AQ505_RS00310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AQ505_RS00315	COG1556	Lactate utilization protein
AQ505_RS00335	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AQ505_RS00350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AQ505_RS00355	COG3530	Putative quorum-sensing-regulated virulence factor
AQ505_RS00375	COG4771	TonB-dependent receptor
AQ505_RS00390	COG1191	sigma factor activity
AQ505_RS00415	COG2967	ApaG domain
AQ505_RS00430	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AQ505_RS00435	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AQ505_RS00440	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AQ505_RS00455	COG0445	tRNA wobble uridine modification
AQ505_RS00460	COG0488	(ABC) transporter
AQ505_RS00465	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AQ505_RS00480	COG1278	Cold shock
AQ505_RS00505	COG0686	Belongs to the AlaDH PNT family
AQ505_RS00510	COG0802	atpase or kinase
AQ505_RS00520	COG1078	dGTPase activity
AQ505_RS00525	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AQ505_RS00530	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AQ505_RS00530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AQ505_RS00535	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AQ505_RS00540	COG3842	ATPase activity
AQ505_RS00550	COG0010	Belongs to the arginase family
AQ505_RS00555	COG1228	amidohydrolase
AQ505_RS00560	COG0708	Exodeoxyribonuclease III
AQ505_RS00585	COG2353	YceI-like domain
AQ505_RS00590	COG3384	dioxygenase
AQ505_RS00600	COG4946	Tricorn protease homolog
AQ505_RS00600	COG1506	peptidase
AQ505_RS00600	COG0823	Involved in the tonB-independent uptake of proteins
AQ505_RS00610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AQ505_RS00625	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AQ505_RS00630	COG2814	Major facilitator Superfamily
AQ505_RS00660	COG1595	DNA-templated transcription, initiation
AQ505_RS00685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AQ505_RS00690	COG2321	neutral zinc metallopeptidase
AQ505_RS00700	COG0784	Response regulator, receiver
AQ505_RS00700	COG5002	protein histidine kinase activity
AQ505_RS00710	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AQ505_RS00720	COG2204	response regulator
AQ505_RS00735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AQ505_RS00740	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AQ505_RS00740	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AQ505_RS00745	COG1024	Enoyl-CoA hydratase
AQ505_RS00775	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AQ505_RS00795	COG0861	Integral membrane protein TerC family
AQ505_RS00820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AQ505_RS00840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AQ505_RS00845	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AQ505_RS00860	COG0519	Catalyzes the synthesis of GMP from XMP
AQ505_RS00870	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AQ505_RS00870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AQ505_RS00875	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AQ505_RS00880	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AQ505_RS00890	COG2234	aminopeptidase activity
AQ505_RS00905	COG0137	argininosuccinate synthase activity
AQ505_RS00910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AQ505_RS00925	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AQ505_RS00935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AQ505_RS00940	COG0823	Involved in the tonB-independent uptake of proteins
AQ505_RS00940	COG1506	peptidase
AQ505_RS00940	COG4946	Tricorn protease homolog
AQ505_RS00945	COG0165	Argininosuccinate lyase
AQ505_RS00955	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AQ505_RS00965	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AQ505_RS00970	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AQ505_RS00975	COG0194	GDP metabolic process
AQ505_RS00980	COG1561	YicC-like family, N-terminal region
AQ505_RS00990	COG0571	ribonuclease III activity
AQ505_RS00995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AQ505_RS01000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AQ505_RS01010	COG0469	pyruvate kinase activity
AQ505_RS01040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AQ505_RS01045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AQ505_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
AQ505_RS01070	COG1074	ATP-dependent DNA helicase activity
AQ505_RS01085	COG0022	dehydrogenase e1 component
AQ505_RS01085	COG0508	dehydrogenase complex catalyzes the overall conversion of
AQ505_RS01090	COG2183	response to ionizing radiation
AQ505_RS01095	COG1522	sequence-specific DNA binding
AQ505_RS01100	COG1228	amidohydrolase
AQ505_RS01105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AQ505_RS01115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AQ505_RS01120	COG0512	Glutamine amidotransferase of anthranilate synthase
AQ505_RS01125	COG0134	indole-3-glycerol-phosphate synthase activity
AQ505_RS01130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AQ505_RS01135	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AQ505_RS01150	COG1597	lipid kinase activity
AQ505_RS01165	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AQ505_RS01180	COG1012	belongs to the aldehyde dehydrogenase family
AQ505_RS01190	COG1809	phosphosulfolactate synthase activity
AQ505_RS01195	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AQ505_RS01210	COG4591	ABC-type transport system involved in lipoprotein release permease component
AQ505_RS01220	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AQ505_RS01235	COG0302	gtp cyclohydrolase
AQ505_RS01240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AQ505_RS01245	COG5000	phosphorelay sensor kinase activity
AQ505_RS01255	COG1649	PFAM Uncharacterised BCR, COG1649
AQ505_RS01260	COG0612	Peptidase, M16
AQ505_RS01265	COG0363	glucosamine-6-phosphate deaminase activity
AQ505_RS01270	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AQ505_RS01280	COG0793	Belongs to the peptidase S41A family
AQ505_RS01290	COG0492	ferredoxin-NADP+ reductase activity
AQ505_RS01295	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AQ505_RS01300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AQ505_RS01360	COG0702	epimerase
AQ505_RS01375	COG4771	TonB-dependent receptor
AQ505_RS01415	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AQ505_RS01430	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AQ505_RS01435	COG1597	lipid kinase activity
AQ505_RS01445	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AQ505_RS01450	COG0811	peptide transport
AQ505_RS01465	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AQ505_RS01485	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AQ505_RS01490	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AQ505_RS01500	COG0649	NAD binding
AQ505_RS01505	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AQ505_RS01515	COG1034	ATP synthesis coupled electron transport
AQ505_RS01520	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AQ505_RS01525	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AQ505_RS01530	COG0839	Belongs to the complex I subunit 6 family
AQ505_RS01535	COG0713	ATP synthesis coupled electron transport
AQ505_RS01540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AQ505_RS01545	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AQ505_RS01550	COG1007	ATP synthesis coupled electron transport
AQ505_RS01555	COG0586	Pfam SNARE associated Golgi protein
AQ505_RS01565	COG1253	flavin adenine dinucleotide binding
AQ505_RS01570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AQ505_RS01580	COG5016	pyruvate
AQ505_RS01580	COG0511	ligase activity, forming carbon-carbon bonds
AQ505_RS01585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AQ505_RS01595	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AQ505_RS01605	COG2353	YceI-like domain
AQ505_RS01630	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AQ505_RS01655	COG1217	gtp-binding protein TYPA
AQ505_RS01660	COG0300	oxidoreductase activity
AQ505_RS01680	COG0705	Rhomboid family
AQ505_RS01690	COG2226	methyltransferase
AQ505_RS01720	COG1011	Hydrolase
AQ505_RS01730	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AQ505_RS01740	COG0556	nucleotide-excision repair
AQ505_RS01745	COG4895	conserved protein (DUF2196)
AQ505_RS01775	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AQ505_RS01790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AQ505_RS01810	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AQ505_RS01820	COG0738	Major facilitator superfamily
AQ505_RS01825	COG3254	rhamnose metabolic process
AQ505_RS01830	COG2721	sulfolactate sulfo-lyase activity
AQ505_RS01835	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS01840	COG0179	Fumarylacetoacetate (FAA) hydrolase
AQ505_RS01850	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS01880	COG1566	PFAM secretion protein HlyD family protein
AQ505_RS01890	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AQ505_RS01890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AQ505_RS01895	COG0529	Catalyzes the synthesis of activated sulfate
AQ505_RS01935	COG1316	TRANSCRIPTIONal
AQ505_RS01940	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AQ505_RS02040	COG1086	Polysaccharide biosynthesis protein
AQ505_RS02045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AQ505_RS02055	COG2089	acid synthase
AQ505_RS02060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AQ505_RS02065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AQ505_RS02070	COG1083	cytidylyl-transferase
AQ505_RS02075	COG0107	imidazoleglycerol-phosphate synthase activity
AQ505_RS02080	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AQ505_RS02090	COG1045	serine acetyltransferase
AQ505_RS02125	COG0438	transferase activity, transferring glycosyl groups
AQ505_RS02135	COG0110	maltose O-acetyltransferase activity
AQ505_RS02150	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AQ505_RS02155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AQ505_RS02160	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AQ505_RS02160	COG0662	Cupin 2, conserved barrel domain protein
AQ505_RS02170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AQ505_RS02190	COG4942	peptidase
AQ505_RS02230	COG1752	Esterase of the alpha-beta hydrolase superfamily
AQ505_RS02245	COG3850	Histidine kinase
AQ505_RS02245	COG2205	protein histidine kinase activity
AQ505_RS02245	COG4999	Histidine kinase
AQ505_RS02245	COG3437	response regulator, receiver
AQ505_RS02255	COG1629	transport
AQ505_RS02260	COG0702	epimerase
AQ505_RS02265	COG1522	sequence-specific DNA binding
AQ505_RS02270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AQ505_RS02275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AQ505_RS02280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AQ505_RS02290	COG2205	protein histidine kinase activity
AQ505_RS02290	COG0784	Response regulator, receiver
AQ505_RS02300	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AQ505_RS02320	COG0402	S-adenosylhomocysteine deaminase activity
AQ505_RS02330	COG1254	Belongs to the acylphosphatase family
AQ505_RS02340	COG0756	dUTP diphosphatase activity
AQ505_RS02360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AQ505_RS02365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AQ505_RS02370	COG0154	amidase activity
AQ505_RS02375	COG4641	Protein conserved in bacteria
AQ505_RS02375	COG1388	LysM domain
AQ505_RS02380	COG0281	malic enzyme
AQ505_RS02380	COG0280	phosphate acetyltransferase
AQ505_RS02385	COG0632	four-way junction helicase activity
AQ505_RS02395	COG0509	glycine decarboxylation via glycine cleavage system
AQ505_RS02425	COG0022	dehydrogenase e1 component
AQ505_RS02430	COG1139	Iron-sulfur cluster binding protein
AQ505_RS02445	COG0698	ribose 5-phosphate isomerase
AQ505_RS02450	COG0805	protein transport
AQ505_RS02455	COG0439	Biotin carboxylase
AQ505_RS02460	COG0511	ligase activity, forming carbon-carbon bonds
AQ505_RS02465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AQ505_RS02470	COG0416	fatty acid biosynthetic process
AQ505_RS02480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AQ505_RS02485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AQ505_RS02495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AQ505_RS02500	COG0537	adenosine 5'-monophosphoramidase activity
AQ505_RS02505	COG0076	glutamate decarboxylase activity
AQ505_RS02515	COG1694	Mazg nucleotide pyrophosphohydrolase
AQ505_RS02520	COG1490	D-aminoacyl-tRNA deacylase activity
AQ505_RS02525	COG1162	GTPase activity
AQ505_RS02530	COG0460	homoserine dehydrogenase
AQ505_RS02530	COG0527	aspartate kinase activity
AQ505_RS02535	COG0083	homoserine kinase activity
AQ505_RS02550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AQ505_RS02565	COG0670	Belongs to the BI1 family
AQ505_RS02575	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AQ505_RS02585	COG1160	GTP binding
AQ505_RS02590	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AQ505_RS02630	COG2855	membrane
AQ505_RS02635	COG2205	protein histidine kinase activity
AQ505_RS02635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AQ505_RS02640	COG2204	response regulator
AQ505_RS02650	COG1959	2 iron, 2 sulfur cluster binding
AQ505_RS02665	COG4464	protein tyrosine phosphatase activity
AQ505_RS02710	COG0438	transferase activity, transferring glycosyl groups
AQ505_RS02720	COG0110	maltose O-acetyltransferase activity
AQ505_RS02815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AQ505_RS02845	COG0463	Glycosyl transferase, family 2
AQ505_RS02860	COG0405	Gamma-glutamyltransferase
AQ505_RS02865	COG2885	chlorophyll binding
AQ505_RS02880	COG1024	Enoyl-CoA hydratase
AQ505_RS02880	COG1250	3-hydroxyacyl-CoA dehydrogenase
AQ505_RS02885	COG0183	Belongs to the thiolase family
AQ505_RS02890	COG1960	acyl-CoA dehydrogenase activity
AQ505_RS02905	COG0415	Belongs to the DNA photolyase family
AQ505_RS02910	COG1090	epimerase
AQ505_RS02915	COG0415	Belongs to the DNA photolyase family
AQ505_RS02925	COG0567	Dehydrogenase, E1 component
AQ505_RS02930	COG0508	dehydrogenase complex catalyzes the overall conversion of
AQ505_RS02950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AQ505_RS02980	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AQ505_RS02985	COG1595	DNA-templated transcription, initiation
AQ505_RS03045	COG3275	phosphorelay sensor kinase activity
AQ505_RS03050	COG3279	Response regulator of the LytR AlgR family
AQ505_RS03075	COG2249	NAD(P)H dehydrogenase (quinone) activity
AQ505_RS03080	COG1741	Belongs to the pirin family
AQ505_RS03090	COG0427	acetyl-CoA hydrolase
AQ505_RS03130	COG3590	peptidase
AQ505_RS03135	COG0517	IMP dehydrogenase activity
AQ505_RS03145	COG1137	ATPase activity
AQ505_RS03150	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AQ505_RS03150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AQ505_RS03155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AQ505_RS03160	COG2198	Histidine kinase
AQ505_RS03160	COG0784	Response regulator, receiver
AQ505_RS03160	COG0643	Histidine kinase
AQ505_RS03180	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AQ505_RS03185	COG3264	Mechanosensitive ion channel
AQ505_RS03185	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AQ505_RS03190	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AQ505_RS03200	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AQ505_RS03230	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AQ505_RS03250	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AQ505_RS03270	COG0101	tRNA pseudouridine synthase activity
AQ505_RS03275	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AQ505_RS03280	COG2027	D-alanyl-D-alanine carboxypeptidase
AQ505_RS03285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AQ505_RS03300	COG2211	Major facilitator Superfamily
AQ505_RS03310	COG0673	inositol 2-dehydrogenase activity
AQ505_RS03315	COG4654	Cytochrome c, class I
AQ505_RS03325	COG0673	inositol 2-dehydrogenase activity
AQ505_RS03340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AQ505_RS03345	COG0217	transcriptional regulatory protein
AQ505_RS03350	COG3693	PFAM glycoside hydrolase, family 10
AQ505_RS03350	COG3507	Belongs to the glycosyl hydrolase 43 family
AQ505_RS03350	COG2382	esterase
AQ505_RS03380	COG0702	epimerase
AQ505_RS03395	COG1054	Belongs to the UPF0176 family
AQ505_RS03400	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS03410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AQ505_RS03435	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AQ505_RS03445	COG1309	transcriptional regulator
AQ505_RS03455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AQ505_RS03470	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AQ505_RS03485	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AQ505_RS03490	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AQ505_RS03505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AQ505_RS03510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AQ505_RS03525	COG1136	(ABC) transporter
AQ505_RS03525	COG0577	efflux transmembrane transporter activity
AQ505_RS03530	COG0316	Belongs to the HesB IscA family
AQ505_RS03540	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AQ505_RS03540	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AQ505_RS03545	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AQ505_RS03570	COG1704	LemA family
AQ505_RS03575	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AQ505_RS03670	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AQ505_RS03670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AQ505_RS03680	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AQ505_RS03690	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AQ505_RS03695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AQ505_RS03725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AQ505_RS03725	COG4651	solute:proton antiporter activity
AQ505_RS03735	COG0196	riboflavin kinase activity
AQ505_RS03740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AQ505_RS03745	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AQ505_RS03750	COG1968	undecaprenyl-diphosphatase activity
AQ505_RS03760	COG2177	Part of the ABC transporter FtsEX involved in
AQ505_RS03770	COG0038	chloride channel
AQ505_RS03775	COG0495	leucyl-tRNA aminoacylation
AQ505_RS03785	COG0747	negative chemotaxis
AQ505_RS03800	COG1192	Involved in chromosome partitioning
AQ505_RS03805	COG1475	DNA binding
AQ505_RS03815	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AQ505_RS03820	COG0681	Belongs to the peptidase S26 family
AQ505_RS03825	COG1940	carbohydrate kinase activity
AQ505_RS03830	COG4206	TonB-dependent receptor
AQ505_RS03830	COG1629	transport
AQ505_RS03840	COG3237	CsbD-like
AQ505_RS03850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AQ505_RS03855	COG3119	arylsulfatase activity
AQ505_RS03860	COG0702	epimerase
AQ505_RS03865	COG1629	transport
AQ505_RS03875	COG1629	transport
AQ505_RS03895	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AQ505_RS03900	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AQ505_RS03905	COG0552	protein localization to endoplasmic reticulum
AQ505_RS03910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AQ505_RS03915	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AQ505_RS03925	COG0612	Peptidase, M16
AQ505_RS03930	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AQ505_RS03940	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AQ505_RS03945	COG4771	TonB-dependent receptor
AQ505_RS03950	COG0702	epimerase
AQ505_RS03955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AQ505_RS03960	COG0666	response to abiotic stimulus
AQ505_RS03965	COG4753	response regulator
AQ505_RS03965	COG2207	Transcriptional regulator
AQ505_RS04005	COG3275	phosphorelay sensor kinase activity
AQ505_RS04015	COG4771	TonB-dependent receptor
AQ505_RS04045	COG1629	transport
AQ505_RS04050	COG0702	epimerase
AQ505_RS04055	COG1073	alpha beta
AQ505_RS04085	COG0745	RESPONSE REGULATOR receiver
AQ505_RS04105	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AQ505_RS04120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AQ505_RS04135	COG0513	Belongs to the DEAD box helicase family
AQ505_RS04145	COG1113	amino acid transport
AQ505_RS04160	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AQ505_RS04200	COG4206	TonB-dependent receptor
AQ505_RS04215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AQ505_RS04220	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AQ505_RS04225	COG3720	iron ion transport
AQ505_RS04230	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AQ505_RS04230	COG0116	Belongs to the methyltransferase superfamily
AQ505_RS04235	COG1127	ABC transporter
AQ505_RS04240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AQ505_RS04245	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS04265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AQ505_RS04280	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AQ505_RS04285	COG0181	hydroxymethylbilane synthase activity
AQ505_RS04290	COG0113	porphobilinogen synthase activity
AQ505_RS04295	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AQ505_RS04300	COG5002	protein histidine kinase activity
AQ505_RS04305	COG0745	RESPONSE REGULATOR receiver
AQ505_RS04315	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AQ505_RS04320	COG1981	membrane
AQ505_RS04340	COG3842	ATPase activity
AQ505_RS04355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AQ505_RS04360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AQ505_RS04365	COG0473	3-isopropylmalate dehydrogenase activity
AQ505_RS04370	COG1119	ATPase activity
AQ505_RS04375	COG0066	3-isopropylmalate dehydratase activity
AQ505_RS04380	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AQ505_RS04385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AQ505_RS04395	COG0440	acetolactate synthase activity
AQ505_RS04400	COG0028	Belongs to the TPP enzyme family
AQ505_RS04415	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AQ505_RS04420	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AQ505_RS04425	COG1091	dTDP-4-dehydrorhamnose reductase activity
AQ505_RS04445	COG1595	DNA-templated transcription, initiation
AQ505_RS04470	COG1704	LemA family
AQ505_RS04485	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AQ505_RS04500	COG0745	RESPONSE REGULATOR receiver
AQ505_RS04505	COG2205	protein histidine kinase activity
AQ505_RS04515	COG3781	membrane
AQ505_RS04530	COG2207	Transcriptional regulator
AQ505_RS04535	COG2814	Major facilitator Superfamily
AQ505_RS04545	COG0563	adenylate kinase activity
AQ505_RS04550	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AQ505_RS04570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AQ505_RS04610	COG4176	ABC-type proline glycine betaine transport system permease component
AQ505_RS04615	COG2113	Glycine betaine
AQ505_RS04620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AQ505_RS04630	COG0126	phosphoglycerate kinase activity
AQ505_RS04635	COG2001	Belongs to the MraZ family
AQ505_RS04640	COG0275	rRNA processing
AQ505_RS04655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AQ505_RS04660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AQ505_RS04665	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AQ505_RS04670	COG0772	Belongs to the SEDS family
AQ505_RS04675	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AQ505_RS04680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AQ505_RS04695	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AQ505_RS04700	COG0156	8-amino-7-oxononanoate synthase activity
AQ505_RS04710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AQ505_RS04715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AQ505_RS04725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AQ505_RS04755	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AQ505_RS04770	COG2814	Major facilitator Superfamily
AQ505_RS04810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AQ505_RS04815	COG0697	spore germination
AQ505_RS04820	COG1522	sequence-specific DNA binding
AQ505_RS04830	COG2197	response regulator
AQ505_RS04875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AQ505_RS04885	COG0205	6-phosphofructokinase activity
AQ505_RS04910	COG0439	Biotin carboxylase
AQ505_RS04950	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AQ505_RS04960	COG0179	Fumarylacetoacetate (FAA) hydrolase
AQ505_RS04975	COG0300	oxidoreductase activity
AQ505_RS04990	COG1368	sulfuric ester hydrolase activity
AQ505_RS04995	COG0069	glutamate synthase activity
AQ505_RS05010	COG1982	Orn Lys Arg decarboxylase major
AQ505_RS05015	COG0531	amino acid
AQ505_RS05040	COG0471	metal ion transport
AQ505_RS05050	COG1053	succinate dehydrogenase
AQ505_RS05055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AQ505_RS05065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AQ505_RS05075	COG0842	Transport permease protein
AQ505_RS05080	COG0423	glycine-tRNA ligase activity
AQ505_RS05085	COG0584	glycerophosphoryl diester phosphodiesterase
AQ505_RS05090	COG1131	(ABC) transporter
AQ505_RS05105	COG1629	transport
AQ505_RS05125	COG0592	DNA-directed DNA polymerase activity
AQ505_RS05130	COG0586	Pfam SNARE associated Golgi protein
AQ505_RS05140	COG0443	Heat shock 70 kDa protein
AQ505_RS05150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AQ505_RS05160	COG0513	Belongs to the DEAD box helicase family
AQ505_RS05180	COG2323	membrane
AQ505_RS05185	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AQ505_RS05210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AQ505_RS05225	COG1138	Cytochrome C-type biogenesis protein
AQ505_RS05255	COG0424	maF-like protein
AQ505_RS05260	COG0248	Ppx GppA phosphatase
AQ505_RS05265	COG1668	transmembrane transport
AQ505_RS05270	COG4152	abc transporter atp-binding protein
AQ505_RS05275	COG0484	heat shock protein binding
AQ505_RS05280	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AQ505_RS05285	COG2884	Cell division ATP-binding protein ftsE
AQ505_RS05300	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AQ505_RS05325	COG0140	phosphoribosyl-ATP diphosphatase activity
AQ505_RS05325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AQ505_RS05330	COG0107	imidazoleglycerol-phosphate synthase activity
AQ505_RS05335	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AQ505_RS05340	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AQ505_RS05345	COG0131	Imidazoleglycerol-phosphate dehydratase
AQ505_RS05345	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AQ505_RS05350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AQ505_RS05355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AQ505_RS05360	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AQ505_RS05365	COG2989	Protein conserved in bacteria
AQ505_RS05390	COG0463	Glycosyl transferase, family 2
AQ505_RS05410	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AQ505_RS05420	COG0484	heat shock protein binding
AQ505_RS05425	COG2814	Major facilitator Superfamily
AQ505_RS05435	COG0724	RNA recognition motif
AQ505_RS05465	COG1858	cytochrome C peroxidase
AQ505_RS05540	COG0339	signal peptide processing
AQ505_RS05555	COG4771	TonB-dependent receptor
AQ505_RS05570	COG3119	arylsulfatase activity
AQ505_RS05590	COG2205	protein histidine kinase activity
AQ505_RS05595	COG2814	Major facilitator Superfamily
AQ505_RS05610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AQ505_RS05630	COG1629	transport
AQ505_RS05630	COG4206	TonB-dependent receptor
AQ505_RS05675	COG1012	belongs to the aldehyde dehydrogenase family
AQ505_RS05680	COG2207	Transcriptional regulator
AQ505_RS05690	COG0583	DNA-binding transcription factor activity
AQ505_RS05695	COG2855	membrane
AQ505_RS05735	COG1104	cysteine desulfurase activity
AQ505_RS05745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AQ505_RS05750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AQ505_RS05750	COG1648	precorrin-2 dehydrogenase activity
AQ505_RS05755	COG0730	response to heat
AQ505_RS05760	COG0175	sulfate reduction
AQ505_RS05770	COG2895	sulfate adenylyltransferase (ATP) activity
AQ505_RS05775	COG0297	glycogen (starch) synthase activity
AQ505_RS05780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AQ505_RS05785	COG4191	Histidine kinase
AQ505_RS05800	COG1136	(ABC) transporter
AQ505_RS05805	COG0577	efflux transmembrane transporter activity
AQ505_RS05810	COG0577	efflux transmembrane transporter activity
AQ505_RS05825	COG0577	efflux transmembrane transporter activity
AQ505_RS05830	COG0577	efflux transmembrane transporter activity
AQ505_RS05830	COG1136	(ABC) transporter
AQ505_RS05835	COG0577	efflux transmembrane transporter activity
AQ505_RS05840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AQ505_RS05855	COG0544	peptidyl-prolyl cis-trans isomerase activity
AQ505_RS05860	COG0740	serine-type endopeptidase activity
AQ505_RS05865	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AQ505_RS05870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AQ505_RS05890	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AQ505_RS05890	COG1796	DNA polymerase
AQ505_RS05895	COG0616	signal peptide processing
AQ505_RS05910	COG1183	phosphatidylcholine synthase activity
AQ505_RS05920	COG0284	orotidine-5'-phosphate decarboxylase activity
AQ505_RS05925	COG0697	spore germination
AQ505_RS05945	COG1674	ftsk spoiiie
AQ505_RS05955	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AQ505_RS05955	COG0321	lipoyl(octanoyl) transferase activity
AQ505_RS05975	COG0367	asparagine synthase
AQ505_RS06000	COG1231	oxidoreductase activity
AQ505_RS06030	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AQ505_RS06040	COG0784	Response regulator, receiver
AQ505_RS06040	COG2205	protein histidine kinase activity
AQ505_RS06040	COG5002	protein histidine kinase activity
AQ505_RS06055	COG0346	lactoylglutathione lyase activity
AQ505_RS06065	COG2151	metal-sulfur cluster biosynthetic enzyme
AQ505_RS06070	COG2166	iron-sulfur cluster assembly
AQ505_RS06075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AQ505_RS06080	COG0719	Fe-S assembly protein
AQ505_RS06090	COG0719	Fe-S assembly protein
AQ505_RS06140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AQ505_RS06150	COG1611	Belongs to the LOG family
AQ505_RS06160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AQ505_RS06165	COG4221	oxidoreductase activity
AQ505_RS06180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AQ505_RS06185	COG0135	phosphoribosylanthranilate isomerase activity
AQ505_RS06190	COG0133	tryptophan synthase activity
AQ505_RS06195	COG0159	tryptophan synthase activity
AQ505_RS06200	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AQ505_RS06205	COG0009	L-threonylcarbamoyladenylate synthase
AQ505_RS06210	COG0069	glutamate synthase activity
AQ505_RS06215	COG0017	Asparaginyl-tRNA synthetase
AQ505_RS06220	COG2205	protein histidine kinase activity
AQ505_RS06225	COG0045	succinate-CoA ligase (ADP-forming) activity
AQ505_RS06230	COG1136	(ABC) transporter
AQ505_RS06255	COG2234	aminopeptidase activity
AQ505_RS06255	COG4935	Belongs to the peptidase S8 family
AQ505_RS06260	COG0667	Aldo Keto reductase
AQ505_RS06270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AQ505_RS06275	COG3655	Transcriptional regulator
AQ505_RS06285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AQ505_RS06290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AQ505_RS06310	COG3059	membrane
AQ505_RS06315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AQ505_RS06315	COG2207	Transcriptional regulator
AQ505_RS06340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AQ505_RS06355	COG4771	TonB-dependent receptor
AQ505_RS06370	COG0583	DNA-binding transcription factor activity
AQ505_RS06380	COG3591	Belongs to the peptidase S1B family
AQ505_RS06385	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AQ505_RS06400	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AQ505_RS06430	COG0328	RNA-DNA hybrid ribonuclease activity
AQ505_RS06435	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AQ505_RS06445	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AQ505_RS06455	COG3279	Response regulator of the LytR AlgR family
AQ505_RS06465	COG3275	phosphorelay sensor kinase activity
AQ505_RS06500	COG1609	Transcriptional regulator
AQ505_RS06520	COG4771	TonB-dependent receptor
AQ505_RS06525	COG0702	epimerase
AQ505_RS06570	COG1914	H( )-stimulated, divalent metal cation uptake system
AQ505_RS06575	COG0047	phosphoribosylformylglycinamidine synthase activity
AQ505_RS06575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AQ505_RS06580	COG3340	Belongs to the peptidase S51 family
AQ505_RS06585	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AQ505_RS06590	COG1984	allophanate hydrolase subunit 2
AQ505_RS06595	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AQ505_RS06600	COG1914	H( )-stimulated, divalent metal cation uptake system
AQ505_RS06620	COG0784	Response regulator, receiver
AQ505_RS06620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AQ505_RS06620	COG2198	Histidine kinase
AQ505_RS06620	COG2205	protein histidine kinase activity
AQ505_RS06625	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AQ505_RS06670	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AQ505_RS06715	COG5002	protein histidine kinase activity
AQ505_RS06725	COG1139	Iron-sulfur cluster binding protein
AQ505_RS06730	COG0247	lactate metabolic process
AQ505_RS06735	COG1609	Transcriptional regulator
AQ505_RS06740	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AQ505_RS06745	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AQ505_RS06750	COG4677	pectinesterase activity
AQ505_RS06755	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS06760	COG3119	arylsulfatase activity
AQ505_RS06765	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AQ505_RS06775	COG0662	Cupin 2, conserved barrel domain protein
AQ505_RS06775	COG2207	Transcriptional regulator
AQ505_RS06780	COG3119	arylsulfatase activity
AQ505_RS06785	COG0163	prenyltransferase activity
AQ505_RS06790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AQ505_RS06800	COG0483	inositol monophosphate 1-phosphatase activity
AQ505_RS06805	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AQ505_RS06830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AQ505_RS06840	COG0450	alkyl hydroperoxide reductase
AQ505_RS06855	COG0527	aspartate kinase activity
AQ505_RS06880	COG1193	negative regulation of DNA recombination
AQ505_RS06885	COG2133	pyrroloquinoline quinone binding
AQ505_RS06890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AQ505_RS06900	COG0572	uridine kinase
AQ505_RS06910	COG0783	Belongs to the Dps family
AQ505_RS06935	COG0442	prolyl-tRNA aminoacylation
AQ505_RS06945	COG0626	cystathionine gamma-synthase activity
AQ505_RS06960	COG0463	Glycosyl transferase, family 2
AQ505_RS06965	COG3104	oligopeptide transport
AQ505_RS06970	COG3104	oligopeptide transport
AQ505_RS06980	COG0183	Belongs to the thiolase family
AQ505_RS06995	COG1480	7TM receptor with intracellular HD hydrolase
AQ505_RS07045	COG2351	hydroxyisourate hydrolase activity
AQ505_RS07120	COG1741	Belongs to the pirin family
AQ505_RS07130	COG4753	response regulator
AQ505_RS07130	COG2207	Transcriptional regulator
AQ505_RS07150	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AQ505_RS07155	COG1027	Aspartate ammonia-lyase
AQ505_RS07160	COG0252	asparaginase activity
AQ505_RS07180	COG4106	trans-aconitate 2-methyltransferase activity
AQ505_RS07225	COG3275	phosphorelay sensor kinase activity
AQ505_RS07235	COG4206	TonB-dependent receptor
AQ505_RS07235	COG1629	transport
AQ505_RS07245	COG3279	Response regulator of the LytR AlgR family
AQ505_RS07250	COG1349	DNA-binding transcription factor activity
AQ505_RS07255	COG0745	RESPONSE REGULATOR receiver
AQ505_RS07255	COG3292	Two component regulator propeller
AQ505_RS07255	COG2205	protein histidine kinase activity
AQ505_RS07265	COG4771	TonB-dependent receptor
AQ505_RS07280	COG3250	beta-galactosidase activity
AQ505_RS07305	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AQ505_RS07330	COG0657	acetylesterase activity
AQ505_RS07330	COG2755	lipolytic protein G-D-S-L family
AQ505_RS07340	COG2217	Heavy metal translocating P-type atpase
AQ505_RS07365	COG0798	PFAM Bile acid sodium symporter
AQ505_RS07370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AQ505_RS07385	COG0659	secondary active sulfate transmembrane transporter activity
AQ505_RS07405	COG0484	heat shock protein binding
AQ505_RS07410	COG0673	inositol 2-dehydrogenase activity
AQ505_RS07420	COG0673	inositol 2-dehydrogenase activity
AQ505_RS07425	COG0673	inositol 2-dehydrogenase activity
AQ505_RS07445	COG0784	Response regulator, receiver
AQ505_RS07445	COG2198	Histidine kinase
AQ505_RS07445	COG2205	protein histidine kinase activity
AQ505_RS07480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AQ505_RS07480	COG1199	ATP-dependent helicase activity
AQ505_RS07495	COG1629	transport
AQ505_RS07505	COG0700	Nucleoside recognition
AQ505_RS07515	COG0706	membrane insertase activity
AQ505_RS07520	COG0504	CTP synthase activity
AQ505_RS07545	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AQ505_RS07550	COG1428	Deoxynucleoside kinase
AQ505_RS07555	COG0180	Tryptophanyl-tRNA synthetase
AQ505_RS07565	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AQ505_RS07570	COG1136	(ABC) transporter
AQ505_RS07575	COG2096	Adenosyltransferase
AQ505_RS07590	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AQ505_RS07595	COG0577	efflux transmembrane transporter activity
AQ505_RS07595	COG1136	(ABC) transporter
AQ505_RS07600	COG0436	Aminotransferase
AQ505_RS07615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AQ505_RS07630	COG1793	dna ligase
AQ505_RS07640	COG1629	transport
AQ505_RS07650	COG0492	ferredoxin-NADP+ reductase activity
AQ505_RS07655	COG5002	protein histidine kinase activity
AQ505_RS07680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AQ505_RS07705	COG1127	ABC transporter
AQ505_RS07710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AQ505_RS07720	COG1368	sulfuric ester hydrolase activity
AQ505_RS07735	COG2333	competence protein COMEC
AQ505_RS07735	COG0658	competence protein
AQ505_RS07750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AQ505_RS07770	COG4251	negative regulation of phosphorylation
AQ505_RS07775	COG5002	protein histidine kinase activity
AQ505_RS07785	COG1522	sequence-specific DNA binding
AQ505_RS07790	COG1136	(ABC) transporter
AQ505_RS07790	COG0577	efflux transmembrane transporter activity
AQ505_RS07795	COG1136	(ABC) transporter
AQ505_RS07800	COG1566	PFAM secretion protein HlyD family protein
AQ505_RS07810	COG3275	phosphorelay sensor kinase activity
AQ505_RS07820	COG1846	Transcriptional regulator
AQ505_RS07825	COG2130	NADP-dependent
AQ505_RS07830	COG1979	alcohol dehydrogenase
AQ505_RS07835	COG0745	RESPONSE REGULATOR receiver
AQ505_RS07840	COG2205	protein histidine kinase activity
AQ505_RS07840	COG2202	Pas domain
AQ505_RS07845	COG1285	pathogenesis
AQ505_RS07855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AQ505_RS07870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AQ505_RS07875	COG0025	NhaP-type Na H and K H
AQ505_RS07880	COG3685	Protein conserved in bacteria
AQ505_RS07885	COG2989	Protein conserved in bacteria
AQ505_RS07915	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AQ505_RS07935	COG2885	chlorophyll binding
AQ505_RS07945	COG4771	TonB-dependent receptor
AQ505_RS07950	COG0702	epimerase
AQ505_RS07960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AQ505_RS08010	COG2815	serine threonine protein kinase
AQ505_RS08010	COG0515	serine threonine protein kinase
AQ505_RS08020	COG0772	Belongs to the SEDS family
AQ505_RS08025	COG0631	protein serine/threonine phosphatase activity
AQ505_RS08050	COG1473	amidohydrolase
AQ505_RS08055	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS08065	COG1484	DNA-dependent DNA replication
AQ505_RS08095	COG4584	PFAM Integrase catalytic
AQ505_RS08100	COG1484	DNA-dependent DNA replication
AQ505_RS08160	COG1484	DNA-dependent DNA replication
AQ505_RS08180	COG1484	DNA-dependent DNA replication
AQ505_RS08190	COG4584	PFAM Integrase catalytic
AQ505_RS08190	COG2390	Transcriptional regulator
AQ505_RS08195	COG1484	DNA-dependent DNA replication
AQ505_RS08285	COG1301	dicarboxylic acid transport
AQ505_RS08290	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AQ505_RS08295	COG0702	epimerase
AQ505_RS08300	COG1629	transport
AQ505_RS08330	COG3292	Two component regulator propeller
AQ505_RS08330	COG2205	protein histidine kinase activity
AQ505_RS08330	COG0745	RESPONSE REGULATOR receiver
AQ505_RS08335	COG5492	domain, Protein
AQ505_RS08340	COG3119	arylsulfatase activity
AQ505_RS08345	COG5492	domain, Protein
AQ505_RS08350	COG4771	TonB-dependent receptor
AQ505_RS08355	COG0702	epimerase
AQ505_RS08365	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AQ505_RS08380	COG4771	TonB-dependent receptor
AQ505_RS08390	COG0477	Major facilitator Superfamily
AQ505_RS08460	COG2310	stress, protein
AQ505_RS08480	COG4771	TonB-dependent receptor
AQ505_RS08510	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AQ505_RS08520	COG3588	fructose-bisphosphate aldolase
AQ505_RS08525	COG1011	Hydrolase
AQ505_RS08560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AQ505_RS08565	COG1131	(ABC) transporter
AQ505_RS08595	COG2070	2-Nitropropane dioxygenase
AQ505_RS08600	COG0577	efflux transmembrane transporter activity
AQ505_RS08610	COG0577	efflux transmembrane transporter activity
AQ505_RS08875	COG2003	Belongs to the UPF0758 family
AQ505_RS08905	COG3275	phosphorelay sensor kinase activity
AQ505_RS08910	COG3279	Response regulator of the LytR AlgR family
AQ505_RS08935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AQ505_RS08945	COG4771	TonB-dependent receptor
AQ505_RS09035	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AQ505_RS09050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AQ505_RS09075	COG4974	Belongs to the 'phage' integrase family
AQ505_RS09090	COG1295	ribonuclease BN
AQ505_RS09095	COG0824	Thioesterase
AQ505_RS09100	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AQ505_RS09110	COG1181	Belongs to the D-alanine--D-alanine ligase family
AQ505_RS09130	COG0824	Thioesterase
AQ505_RS09135	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AQ505_RS09140	COG1185	polyribonucleotide nucleotidyltransferase activity
AQ505_RS09145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AQ505_RS09150	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AQ505_RS09155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AQ505_RS09180	COG1702	phosphate starvation-inducible protein PhoH
AQ505_RS09185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AQ505_RS09205	COG0860	N-Acetylmuramoyl-L-alanine amidase
AQ505_RS09210	COG0860	N-Acetylmuramoyl-L-alanine amidase
AQ505_RS09220	COG1058	Belongs to the CinA family
AQ505_RS09220	COG1546	Belongs to the CinA family
AQ505_RS09225	COG0508	dehydrogenase complex catalyzes the overall conversion of
AQ505_RS09235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AQ505_RS09245	COG0626	cystathionine gamma-synthase activity
AQ505_RS09260	COG1858	cytochrome C peroxidase
AQ505_RS09270	COG0702	epimerase
AQ505_RS09275	COG4771	TonB-dependent receptor
AQ505_RS09300	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AQ505_RS09305	COG0406	alpha-ribazole phosphatase activity
AQ505_RS09315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AQ505_RS09320	COG0791	NLP P60 protein
AQ505_RS09325	COG3387	PFAM Glycoside hydrolase 15-related
AQ505_RS09330	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AQ505_RS09365	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AQ505_RS09375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AQ505_RS09375	COG3153	acetyltransferase
AQ505_RS09380	COG2255	four-way junction helicase activity
AQ505_RS09385	COG1250	3-hydroxyacyl-CoA dehydrogenase
AQ505_RS09390	COG0259	pyridoxamine-phosphate oxidase activity
AQ505_RS09395	COG1678	Uncharacterized ACR, COG1678
AQ505_RS09400	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AQ505_RS09405	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AQ505_RS09410	COG2081	HI0933 family
AQ505_RS09480	COG4771	TonB-dependent receptor
AQ505_RS09505	COG0640	Transcriptional regulator
AQ505_RS09525	COG4584	PFAM Integrase catalytic
AQ505_RS09525	COG2390	Transcriptional regulator
AQ505_RS09530	COG1484	DNA-dependent DNA replication
AQ505_RS09585	COG3275	phosphorelay sensor kinase activity
AQ505_RS09590	COG3279	Response regulator of the LytR AlgR family
AQ505_RS09595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AQ505_RS09600	COG1733	regulation of RNA biosynthetic process
AQ505_RS09620	COG0488	(ABC) transporter
AQ505_RS09635	COG1629	transport
AQ505_RS09655	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AQ505_RS09660	COG0612	Peptidase, M16
AQ505_RS09685	COG4771	TonB-dependent receptor
AQ505_RS09695	COG1228	amidohydrolase
AQ505_RS09700	COG0514	ATP-dependent DNA helicase (RecQ)
AQ505_RS09710	COG2270	Major facilitator Superfamily
AQ505_RS09715	COG0247	lactate metabolic process
AQ505_RS09720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AQ505_RS09725	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AQ505_RS09730	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AQ505_RS09735	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AQ505_RS09740	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AQ505_RS09745	COG0156	8-amino-7-oxononanoate synthase activity
AQ505_RS09760	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AQ505_RS09775	COG4771	TonB-dependent receptor
AQ505_RS09830	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AQ505_RS09835	COG2244	polysaccharide biosynthetic process
AQ505_RS09850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AQ505_RS09865	COG0438	transferase activity, transferring glycosyl groups
AQ505_RS09880	COG0367	asparagine synthase
AQ505_RS09885	COG0367	asparagine synthase
AQ505_RS09925	COG1086	Polysaccharide biosynthesis protein
AQ505_RS09935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AQ505_RS09950	COG0489	protein tyrosine kinase activity
AQ505_RS09950	COG3206	protein involved in exopolysaccharide biosynthesis
AQ505_RS09960	COG2326	polyphosphate kinase activity
AQ505_RS09995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AQ505_RS10025	COG2814	Major facilitator Superfamily
AQ505_RS10030	COG2207	Transcriptional regulator
AQ505_RS10045	COG2310	stress, protein
AQ505_RS10050	COG2310	stress, protein
AQ505_RS10055	COG3853	Toxic anion resistance protein (TelA)
AQ505_RS10075	COG2885	chlorophyll binding
AQ505_RS10080	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AQ505_RS10085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AQ505_RS10090	COG1278	Cold shock
AQ505_RS10105	COG0745	RESPONSE REGULATOR receiver
AQ505_RS10145	COG0438	transferase activity, transferring glycosyl groups
AQ505_RS10150	COG1215	transferase activity, transferring glycosyl groups
AQ505_RS10165	COG1442	glycosyl transferase family 8
AQ505_RS10215	COG1216	Glycosyl transferase, family 2
AQ505_RS10265	COG1215	transferase activity, transferring glycosyl groups
AQ505_RS10270	COG1215	transferase activity, transferring glycosyl groups
AQ505_RS10285	COG3321	synthase
AQ505_RS10285	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS10285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AQ505_RS10285	COG4221	oxidoreductase activity
AQ505_RS10315	COG4717	serine-type aminopeptidase activity
AQ505_RS10320	COG1956	GAF domain-containing protein
AQ505_RS10325	COG2094	Belongs to the DNA glycosylase MPG family
AQ505_RS10330	COG3844	kynureninase activity
AQ505_RS10335	COG3781	membrane
AQ505_RS10340	COG0123	including yeast histone deacetylase and acetoin utilization protein
AQ505_RS10365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AQ505_RS10390	COG2211	Major facilitator Superfamily
AQ505_RS10400	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AQ505_RS10420	COG0305	Participates in initiation and elongation during chromosome replication
AQ505_RS10425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AQ505_RS10430	COG0443	Heat shock 70 kDa protein
AQ505_RS10440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AQ505_RS10440	COG0517	IMP dehydrogenase activity
AQ505_RS10445	COG0514	ATP-dependent DNA helicase (RecQ)
AQ505_RS10450	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AQ505_RS10455	COG3047	cAMP biosynthetic process
AQ505_RS10455	COG2885	chlorophyll binding
AQ505_RS10460	COG0602	queuosine metabolic process
AQ505_RS10470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AQ505_RS10475	COG0481	GTPase activity
AQ505_RS10480	COG3142	Participates in the control of copper homeostasis
AQ505_RS10485	COG1446	asparaginase
AQ505_RS10490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AQ505_RS10495	COG0436	Aminotransferase
AQ505_RS10500	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AQ505_RS10515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AQ505_RS10530	COG0667	Aldo Keto reductase
AQ505_RS10535	COG0076	glutamate decarboxylase activity
AQ505_RS10545	COG3132	Protein of unknown function, DUF480
AQ505_RS10550	COG0028	Belongs to the TPP enzyme family
AQ505_RS10555	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AQ505_RS10560	COG2824	Alkylphosphonate utilization operon protein PhnA
AQ505_RS10565	COG1794	racemase activity, acting on amino acids and derivatives
AQ505_RS10570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AQ505_RS10580	COG0697	spore germination
AQ505_RS10585	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AQ505_RS10610	COG2315	Protein conserved in bacteria
AQ505_RS10630	COG2814	Major facilitator Superfamily
AQ505_RS10635	COG3279	Response regulator of the LytR AlgR family
AQ505_RS10665	COG4206	TonB-dependent receptor
AQ505_RS10665	COG1629	transport
AQ505_RS10700	COG1629	transport
AQ505_RS10725	COG1295	ribonuclease BN
AQ505_RS10725	COG1959	2 iron, 2 sulfur cluster binding
AQ505_RS10745	COG1733	regulation of RNA biosynthetic process
AQ505_RS10750	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS10760	COG1629	transport
AQ505_RS10785	COG1611	Belongs to the LOG family
AQ505_RS10805	COG2819	hydrolase of the alpha beta superfamily
AQ505_RS10815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AQ505_RS10845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AQ505_RS10860	COG2378	regulation of single-species biofilm formation
AQ505_RS10875	COG2755	lipolytic protein G-D-S-L family
AQ505_RS10875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AQ505_RS10885	COG4977	sequence-specific DNA binding
AQ505_RS10885	COG1917	Cupin 2, conserved barrel domain protein
AQ505_RS10985	COG4974	Belongs to the 'phage' integrase family
AQ505_RS11000	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AQ505_RS11010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AQ505_RS11020	COG4912	Dna alkylation repair
AQ505_RS11035	COG3279	Response regulator of the LytR AlgR family
AQ505_RS11060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AQ505_RS11065	COG2972	Histidine kinase
AQ505_RS11105	COG1278	Cold shock
AQ505_RS11120	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS11165	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AQ505_RS11175	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AQ505_RS11215	COG2814	Major facilitator Superfamily
AQ505_RS11235	COG3345	alpha-galactosidase
AQ505_RS11250	COG1629	transport
AQ505_RS11255	COG0702	epimerase
AQ505_RS11270	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AQ505_RS11280	COG0702	epimerase
AQ505_RS11285	COG4771	TonB-dependent receptor
AQ505_RS11290	COG2205	protein histidine kinase activity
AQ505_RS11290	COG3292	Two component regulator propeller
AQ505_RS11290	COG0745	RESPONSE REGULATOR receiver
AQ505_RS11360	COG3119	arylsulfatase activity
AQ505_RS11390	COG3047	cAMP biosynthetic process
AQ505_RS11435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AQ505_RS11465	COG4682	membrane
AQ505_RS11495	COG4771	TonB-dependent receptor
AQ505_RS11500	COG0702	epimerase
AQ505_RS11505	COG3408	Glycogen debranching enzyme
AQ505_RS11505	COG3119	arylsulfatase activity
AQ505_RS11510	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AQ505_RS11515	COG0583	DNA-binding transcription factor activity
AQ505_RS11530	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AQ505_RS11530	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AQ505_RS11570	COG1484	DNA-dependent DNA replication
AQ505_RS11590	COG4977	sequence-specific DNA binding
AQ505_RS11590	COG1917	Cupin 2, conserved barrel domain protein
AQ505_RS11615	COG0604	alcohol dehydrogenase
AQ505_RS11625	COG5002	protein histidine kinase activity
AQ505_RS11630	COG1595	DNA-templated transcription, initiation
AQ505_RS11640	COG1629	transport
AQ505_RS11640	COG4206	TonB-dependent receptor
AQ505_RS11645	COG0702	epimerase
AQ505_RS11675	COG0702	epimerase
AQ505_RS11680	COG4771	TonB-dependent receptor
AQ505_RS11690	COG2271	Major facilitator Superfamily
AQ505_RS11700	COG1917	Cupin 2, conserved barrel domain protein
AQ505_RS11710	COG2186	Transcriptional regulator
AQ505_RS11735	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AQ505_RS11745	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AQ505_RS11765	COG4206	TonB-dependent receptor
AQ505_RS11765	COG1629	transport
AQ505_RS11770	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AQ505_RS11775	COG3537	Alpha-1,2-mannosidase
AQ505_RS11825	COG4771	TonB-dependent receptor
AQ505_RS11830	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AQ505_RS11840	COG3590	peptidase
AQ505_RS11870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AQ505_RS11875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AQ505_RS11885	COG4771	TonB-dependent receptor
AQ505_RS11945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AQ505_RS11950	COG1742	UPF0060 membrane protein
AQ505_RS11965	COG0745	RESPONSE REGULATOR receiver
AQ505_RS11970	COG5002	protein histidine kinase activity
AQ505_RS11970	COG3850	Histidine kinase
AQ505_RS11980	COG0831	urea catabolic process
AQ505_RS11985	COG0832	Belongs to the urease beta subunit family
AQ505_RS11990	COG0804	urea catabolic process
AQ505_RS11995	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AQ505_RS12000	COG0830	nickel cation binding
AQ505_RS12005	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AQ505_RS12010	COG0829	nickel cation binding
AQ505_RS12020	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AQ505_RS12025	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AQ505_RS12035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AQ505_RS12045	COG4774	siderophore transport
AQ505_RS12055	COG1120	ATPase activity
AQ505_RS12060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AQ505_RS12065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AQ505_RS12110	COG4771	TonB-dependent receptor
AQ505_RS12240	COG4771	TonB-dependent receptor
AQ505_RS12245	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AQ505_RS12260	COG2272	Belongs to the type-B carboxylesterase lipase family
AQ505_RS12270	COG4753	response regulator
AQ505_RS12270	COG2207	Transcriptional regulator
AQ505_RS12315	COG1629	transport
AQ505_RS12320	COG0702	epimerase
AQ505_RS12350	COG0673	inositol 2-dehydrogenase activity
AQ505_RS12420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AQ505_RS12465	COG0038	chloride channel
AQ505_RS12470	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AQ505_RS12500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AQ505_RS12510	COG5002	protein histidine kinase activity
AQ505_RS12515	COG0745	RESPONSE REGULATOR receiver
AQ505_RS12520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AQ505_RS12530	COG2823	Periplasmic or secreted lipoprotein
AQ505_RS12535	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS12540	COG0745	RESPONSE REGULATOR receiver
AQ505_RS12545	COG4191	Histidine kinase
AQ505_RS12555	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AQ505_RS12575	COG1012	belongs to the aldehyde dehydrogenase family
AQ505_RS12590	COG0588	phosphoglycerate mutase activity
AQ505_RS12610	COG2205	protein histidine kinase activity
AQ505_RS12610	COG3437	response regulator, receiver
AQ505_RS12610	COG3850	Histidine kinase
AQ505_RS12610	COG4999	Histidine kinase
AQ505_RS12615	COG5002	protein histidine kinase activity
AQ505_RS12615	COG0784	Response regulator, receiver
AQ505_RS12635	COG1127	ABC transporter
AQ505_RS12640	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AQ505_RS12660	COG1611	Belongs to the LOG family
AQ505_RS12700	COG4584	PFAM Integrase catalytic
AQ505_RS12705	COG1484	DNA-dependent DNA replication
AQ505_RS12800	COG4206	TonB-dependent receptor
AQ505_RS12800	COG1629	transport
AQ505_RS12915	COG0484	heat shock protein binding
AQ505_RS12935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AQ505_RS12950	COG2135	peptidase activity
AQ505_RS13050	COG0640	Transcriptional regulator
AQ505_RS13105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AQ505_RS13120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AQ505_RS13125	COG0436	Aminotransferase
AQ505_RS13130	COG2201	protein-glutamate methylesterase activity
AQ505_RS13135	COG4251	negative regulation of phosphorylation
AQ505_RS13210	COG2217	Heavy metal translocating P-type atpase
AQ505_RS13215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AQ505_RS13255	COG0667	Aldo Keto reductase
AQ505_RS13265	COG2378	regulation of single-species biofilm formation
AQ505_RS13305	COG1595	DNA-templated transcription, initiation
AQ505_RS13315	COG4771	TonB-dependent receptor
AQ505_RS13335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AQ505_RS13385	COG1690	Belongs to the RtcB family
AQ505_RS13415	COG1484	DNA-dependent DNA replication
AQ505_RS13435	COG4584	PFAM Integrase catalytic
AQ505_RS13440	COG1484	DNA-dependent DNA replication
AQ505_RS13525	COG0427	acetyl-CoA hydrolase
AQ505_RS13530	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AQ505_RS13545	COG1959	2 iron, 2 sulfur cluster binding
AQ505_RS13560	COG2084	Dehydrogenase
AQ505_RS13570	COG0025	NhaP-type Na H and K H
AQ505_RS13575	COG1132	(ABC) transporter
AQ505_RS13620	COG1609	Transcriptional regulator
AQ505_RS13625	COG3292	Two component regulator propeller
AQ505_RS13625	COG0745	RESPONSE REGULATOR receiver
AQ505_RS13625	COG2205	protein histidine kinase activity
AQ505_RS13630	COG1501	Belongs to the glycosyl hydrolase 31 family
AQ505_RS13635	COG4206	TonB-dependent receptor
AQ505_RS13635	COG1629	transport
AQ505_RS13650	COG3250	beta-galactosidase activity
AQ505_RS13680	COG1695	Transcriptional regulator
AQ505_RS13690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AQ505_RS13705	COG1595	DNA-templated transcription, initiation
AQ505_RS13725	COG0737	Belongs to the 5'-nucleotidase family
AQ505_RS13735	COG0482	sulfurtransferase activity
AQ505_RS13740	COG3537	Alpha-1,2-mannosidase
AQ505_RS13750	COG0813	purine-nucleoside phosphorylase activity
AQ505_RS13755	COG0488	(ABC) transporter
AQ505_RS13765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AQ505_RS13790	COG0513	Belongs to the DEAD box helicase family
AQ505_RS13815	COG4677	pectinesterase activity
AQ505_RS13820	COG0667	Aldo Keto reductase
AQ505_RS13825	COG1733	regulation of RNA biosynthetic process
AQ505_RS13915	COG4974	Belongs to the 'phage' integrase family
AQ505_RS13925	COG2267	carboxylic ester hydrolase activity
AQ505_RS13930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AQ505_RS13935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AQ505_RS13945	COG0069	glutamate synthase activity
AQ505_RS13945	COG0070	glutamate synthase
AQ505_RS13945	COG0067	glutamate synthase
AQ505_RS13955	COG1629	transport
AQ505_RS13970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AQ505_RS13995	COG2972	Histidine kinase
AQ505_RS14000	COG2205	protein histidine kinase activity
AQ505_RS14005	COG0730	response to heat
AQ505_RS14010	COG1764	response to oxidative stress
AQ505_RS14015	COG1289	transmembrane transporter activity
AQ505_RS14030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AQ505_RS14055	COG0534	Mate efflux family protein
AQ505_RS14060	COG2239	Acts as a magnesium transporter
AQ505_RS14065	COG0598	Magnesium transport protein CorA
AQ505_RS14080	COG1215	transferase activity, transferring glycosyl groups
AQ505_RS14090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AQ505_RS14095	COG4974	Belongs to the 'phage' integrase family
AQ505_RS14100	COG2890	protein-(glutamine-N5) methyltransferase activity
AQ505_RS14105	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AQ505_RS14105	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AQ505_RS14110	COG0697	spore germination
AQ505_RS14115	COG1739	Uncharacterized protein family UPF0029
AQ505_RS14130	COG0702	epimerase
AQ505_RS14135	COG1629	transport
AQ505_RS14165	COG0598	Magnesium transport protein CorA
AQ505_RS14180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AQ505_RS14185	COG1846	Transcriptional regulator
AQ505_RS14190	COG1673	EVE domain
AQ505_RS14195	COG0386	Belongs to the glutathione peroxidase family
AQ505_RS14200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AQ505_RS14200	COG1754	DNA topoisomerase type I activity
AQ505_RS14210	COG2373	Large extracellular alpha-helical protein
AQ505_RS14215	COG4953	penicillin-binding protein 1C
AQ505_RS14230	COG0724	RNA recognition motif
AQ505_RS14265	COG0156	8-amino-7-oxononanoate synthase activity
AQ505_RS14275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AQ505_RS14290	COG1570	exodeoxyribonuclease VII activity
AQ505_RS14305	COG1619	proteins homologs of microcin C7 resistance protein MccF
AQ505_RS14325	COG0673	inositol 2-dehydrogenase activity
AQ505_RS14340	COG0477	Major facilitator Superfamily
AQ505_RS14345	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS14350	COG1078	dGTPase activity
AQ505_RS14370	COG4181	ATPase activity
AQ505_RS14380	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AQ505_RS14400	COG2814	Major facilitator Superfamily
AQ505_RS14410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AQ505_RS14420	COG4771	TonB-dependent receptor
AQ505_RS14425	COG2186	Transcriptional regulator
AQ505_RS14430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AQ505_RS14435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AQ505_RS14445	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AQ505_RS14455	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AQ505_RS14455	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AQ505_RS14485	COG2249	NAD(P)H dehydrogenase (quinone) activity
AQ505_RS14515	COG5002	protein histidine kinase activity
AQ505_RS14545	COG3279	Response regulator of the LytR AlgR family
AQ505_RS14555	COG2972	Histidine kinase
AQ505_RS14575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AQ505_RS14585	COG4232	protein-disulfide reductase activity
AQ505_RS14595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AQ505_RS14625	COG1309	transcriptional regulator
AQ505_RS14650	COG1609	Transcriptional regulator
AQ505_RS14655	COG1312	Catalyzes the dehydration of D-mannonate
AQ505_RS14660	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS14665	COG5002	protein histidine kinase activity
AQ505_RS14670	COG0745	RESPONSE REGULATOR receiver
AQ505_RS14675	COG1368	sulfuric ester hydrolase activity
AQ505_RS14690	COG0673	inositol 2-dehydrogenase activity
AQ505_RS14735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AQ505_RS14750	COG1349	DNA-binding transcription factor activity
AQ505_RS14755	COG1012	belongs to the aldehyde dehydrogenase family
AQ505_RS14760	COG2271	Major facilitator Superfamily
AQ505_RS14765	COG0800	Aldolase
AQ505_RS14775	COG1904	glucuronate isomerase
AQ505_RS14780	COG2721	sulfolactate sulfo-lyase activity
AQ505_RS14785	COG0246	Mannitol dehydrogenase
AQ505_RS14800	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AQ505_RS14815	COG4677	pectinesterase activity
AQ505_RS14825	COG2755	lipolytic protein G-D-S-L family
AQ505_RS14830	COG2755	lipolytic protein G-D-S-L family
AQ505_RS14840	COG0702	epimerase
AQ505_RS14845	COG4771	TonB-dependent receptor
AQ505_RS14850	COG1609	Transcriptional regulator
AQ505_RS14860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AQ505_RS14875	COG4771	TonB-dependent receptor
AQ505_RS14900	COG0312	modulator of DNA gyrase
AQ505_RS14935	COG0714	Associated with various cellular activities
AQ505_RS15020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AQ505_RS15025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AQ505_RS15030	COG0673	inositol 2-dehydrogenase activity
AQ505_RS15045	COG0604	alcohol dehydrogenase
AQ505_RS15055	COG1285	pathogenesis
AQ505_RS15070	COG1082	Xylose isomerase domain protein TIM barrel
AQ505_RS15080	COG0456	acetyltransferase
AQ505_RS15095	COG3537	Alpha-1,2-mannosidase
AQ505_RS15105	COG0561	phosphatase activity
AQ505_RS15110	COG1629	transport
AQ505_RS15125	COG0667	Aldo Keto reductase
AQ505_RS15145	COG1333	cytochrome c biogenesis protein
AQ505_RS15145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AQ505_RS15145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AQ505_RS15145	COG1333	cytochrome c biogenesis protein
AQ505_RS15150	COG3507	Belongs to the glycosyl hydrolase 43 family
AQ505_RS15190	COG0604	alcohol dehydrogenase
AQ505_RS15190	COG3321	synthase
AQ505_RS15195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AQ505_RS15200	COG0596	Alpha beta hydrolase
AQ505_RS15210	COG3119	arylsulfatase activity
AQ505_RS15215	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AQ505_RS15220	COG0402	S-adenosylhomocysteine deaminase activity
AQ505_RS15245	COG1063	alcohol dehydrogenase
AQ505_RS15250	COG1733	regulation of RNA biosynthetic process
AQ505_RS15275	COG3250	beta-galactosidase activity
AQ505_RS15285	COG1629	transport
AQ505_RS15305	COG3250	beta-galactosidase activity
AQ505_RS15310	COG5002	protein histidine kinase activity
AQ505_RS15320	COG2323	membrane
AQ505_RS15335	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AQ505_RS15340	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AQ505_RS15350	COG0517	IMP dehydrogenase activity
AQ505_RS15350	COG1125	glycine betaine transport
AQ505_RS15355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AQ505_RS15375	COG3264	Mechanosensitive ion channel
AQ505_RS15375	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AQ505_RS15395	COG1309	transcriptional regulator
AQ505_RS15405	COG2205	protein histidine kinase activity
AQ505_RS15410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AQ505_RS15430	COG4948	Mandelate Racemase Muconate Lactonizing
AQ505_RS15445	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS15465	COG4771	TonB-dependent receptor
AQ505_RS15470	COG0702	epimerase
AQ505_RS15520	COG1733	regulation of RNA biosynthetic process
AQ505_RS15530	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AQ505_RS15555	COG0523	cobalamin synthesis protein
AQ505_RS15565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AQ505_RS15570	COG0025	NhaP-type Na H and K H
AQ505_RS15585	COG4771	TonB-dependent receptor
AQ505_RS15595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AQ505_RS15620	COG0668	transmembrane transport
AQ505_RS15625	COG0693	protein deglycase activity
AQ505_RS15650	COG0702	epimerase
AQ505_RS15655	COG4771	TonB-dependent receptor
AQ505_RS15665	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AQ505_RS15695	COG4977	sequence-specific DNA binding
AQ505_RS15720	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AQ505_RS15720	COG3264	Mechanosensitive ion channel
AQ505_RS15750	COG0612	Peptidase, M16
AQ505_RS15755	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AQ505_RS15765	COG1131	(ABC) transporter
AQ505_RS15775	COG0702	epimerase
AQ505_RS15780	COG4771	TonB-dependent receptor
AQ505_RS15825	COG2132	Multicopper oxidase
AQ505_RS15865	COG0584	glycerophosphoryl diester phosphodiesterase
AQ505_RS15880	COG4206	TonB-dependent receptor
AQ505_RS15880	COG1629	transport
AQ505_RS15895	COG1115	amino acid carrier protein
AQ505_RS15910	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AQ505_RS15915	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AQ505_RS15920	COG1522	sequence-specific DNA binding
AQ505_RS15925	COG1607	acyl-coa hydrolase
AQ505_RS15960	COG0738	Major facilitator superfamily
AQ505_RS15965	COG0246	Mannitol dehydrogenase
AQ505_RS16000	COG0667	Aldo Keto reductase
AQ505_RS16030	COG1858	cytochrome C peroxidase
AQ505_RS16070	COG1166	arginine decarboxylase activity
AQ505_RS16075	COG0784	Response regulator, receiver
AQ505_RS16075	COG2205	protein histidine kinase activity
AQ505_RS16080	COG0708	Exodeoxyribonuclease III
AQ505_RS16110	COG0612	Peptidase, M16
AQ505_RS16115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AQ505_RS16125	COG4206	TonB-dependent receptor
AQ505_RS16125	COG1629	transport
AQ505_RS16140	COG4585	Histidine kinase
AQ505_RS16150	COG1114	Component of the transport system for branched-chain amino acids
AQ505_RS16160	COG3685	Protein conserved in bacteria
AQ505_RS16165	COG0745	RESPONSE REGULATOR receiver
AQ505_RS16170	COG2205	protein histidine kinase activity
AQ505_RS16175	COG3250	beta-galactosidase activity
AQ505_RS16200	COG4206	TonB-dependent receptor
AQ505_RS16200	COG1629	transport
AQ505_RS16205	COG2205	protein histidine kinase activity
AQ505_RS16205	COG0745	RESPONSE REGULATOR receiver
AQ505_RS16205	COG3292	Two component regulator propeller
AQ505_RS16210	COG4297	protein containing double-stranded beta helix domain
AQ505_RS16230	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AQ505_RS16270	COG2205	protein histidine kinase activity
AQ505_RS16275	COG5002	protein histidine kinase activity
AQ505_RS16285	COG1285	pathogenesis
AQ505_RS16295	COG0667	Aldo Keto reductase
AQ505_RS16310	COG0457	Tetratricopeptide repeat
AQ505_RS16315	COG2814	Major facilitator Superfamily
AQ505_RS16335	COG4774	siderophore transport
AQ505_RS16355	COG2351	hydroxyisourate hydrolase activity
AQ505_RS16360	COG4716	Myosin-crossreactive antigen
AQ505_RS16375	COG5002	protein histidine kinase activity
AQ505_RS16410	COG1595	DNA-templated transcription, initiation
AQ505_RS16420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AQ505_RS16425	COG0303	'Molybdopterin
AQ505_RS16445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AQ505_RS16450	COG0314	molybdopterin synthase activity
AQ505_RS16465	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AQ505_RS16470	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AQ505_RS16475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AQ505_RS16480	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AQ505_RS16485	COG1595	DNA-templated transcription, initiation
AQ505_RS16520	COG1629	transport
AQ505_RS16530	COG4206	TonB-dependent receptor
AQ505_RS16530	COG1629	transport
AQ505_RS16555	COG4529	Protein conserved in bacteria
AQ505_RS16590	COG1335	isochorismatase
AQ505_RS16620	COG3046	protein related to deoxyribodipyrimidine photolyase
AQ505_RS16625	COG0415	Belongs to the DNA photolyase family
AQ505_RS16645	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS16660	COG1233	COG1233 Phytoene dehydrogenase and related
AQ505_RS16750	COG2003	Belongs to the UPF0758 family
AQ505_RS16835	COG1629	transport
AQ505_RS16885	COG0456	acetyltransferase
AQ505_RS16885	COG1846	Transcriptional regulator
AQ505_RS16910	COG2351	hydroxyisourate hydrolase activity
AQ505_RS16945	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AQ505_RS16950	COG0745	RESPONSE REGULATOR receiver
AQ505_RS16955	COG5002	protein histidine kinase activity
AQ505_RS16955	COG3850	Histidine kinase
AQ505_RS16965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AQ505_RS17065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AQ505_RS17070	COG1127	ABC transporter
AQ505_RS17085	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AQ505_RS17120	COG1012	belongs to the aldehyde dehydrogenase family
AQ505_RS17135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AQ505_RS17140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AQ505_RS17145	COG4191	Histidine kinase
AQ505_RS17150	COG0745	RESPONSE REGULATOR receiver
AQ505_RS17175	COG0538	isocitrate dehydrogenase activity
AQ505_RS17195	COG0156	8-amino-7-oxononanoate synthase activity
AQ505_RS17200	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AQ505_RS17205	COG0509	glycine decarboxylation via glycine cleavage system
AQ505_RS17240	COG3685	Protein conserved in bacteria
AQ505_RS17250	COG5002	protein histidine kinase activity
AQ505_RS17255	COG5002	protein histidine kinase activity
AQ505_RS17260	COG4191	Histidine kinase
AQ505_RS17300	COG3345	alpha-galactosidase
AQ505_RS17315	COG0402	S-adenosylhomocysteine deaminase activity
AQ505_RS17345	COG5002	protein histidine kinase activity
AQ505_RS17350	COG0784	Response regulator, receiver
AQ505_RS17350	COG5002	protein histidine kinase activity
AQ505_RS17350	COG2198	Histidine kinase
AQ505_RS17355	COG5002	protein histidine kinase activity
AQ505_RS17395	COG2003	Belongs to the UPF0758 family
AQ505_RS17420	COG4974	Belongs to the 'phage' integrase family
AQ505_RS17430	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AQ505_RS17435	COG0628	permease
AQ505_RS17445	COG0018	arginyl-trna synthetase
AQ505_RS17450	COG0010	Belongs to the arginase family
AQ505_RS17455	COG1166	arginine decarboxylase activity
AQ505_RS17460	COG0071	Belongs to the small heat shock protein (HSP20) family
AQ505_RS17470	COG0277	FAD linked oxidase domain protein
AQ505_RS17480	COG1960	acyl-CoA dehydrogenase activity
AQ505_RS17495	COG0019	diaminopimelate decarboxylase activity
AQ505_RS17500	COG0527	aspartate kinase activity
AQ505_RS17505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AQ505_RS17520	COG4251	negative regulation of phosphorylation
AQ505_RS17530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AQ505_RS17535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AQ505_RS17540	COG1764	response to oxidative stress
AQ505_RS17560	COG1064	alcohol dehydrogenase
AQ505_RS17575	COG0579	oxidoreductase
AQ505_RS17585	COG4804	nuclease activity
AQ505_RS17590	COG1012	belongs to the aldehyde dehydrogenase family
AQ505_RS17615	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AQ505_RS17630	COG0671	phosphoesterase, PA-phosphatase related
AQ505_RS17635	COG0671	phosphoesterase, PA-phosphatase related
AQ505_RS17640	COG0668	transmembrane transport
AQ505_RS17645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AQ505_RS17660	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AQ505_RS17675	COG1309	transcriptional regulator
AQ505_RS17695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AQ505_RS17700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AQ505_RS17705	COG2011	ABC-type metal ion transport system permease component
AQ505_RS17710	COG1464	Belongs to the NlpA lipoprotein family
AQ505_RS17715	COG3119	arylsulfatase activity
AQ505_RS17750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AQ505_RS17755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AQ505_RS17760	COG1780	Probably involved in ribonucleotide reductase function
AQ505_RS17775	COG0387	Pfam Sodium calcium exchanger
AQ505_RS17785	COG5002	protein histidine kinase activity
AQ505_RS17790	COG3047	cAMP biosynthetic process
AQ505_RS17790	COG2885	chlorophyll binding
AQ505_RS17805	COG0671	phosphoesterase, PA-phosphatase related
AQ505_RS17810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AQ505_RS17830	COG0640	Transcriptional regulator
AQ505_RS17855	COG2197	response regulator
AQ505_RS17865	COG4585	Histidine kinase
AQ505_RS17870	COG1278	Cold shock
AQ505_RS17885	COG0006	proline dipeptidase activity
AQ505_RS17920	COG3119	arylsulfatase activity
AQ505_RS17935	COG2329	Antibiotic biosynthesis monooxygenase
AQ505_RS17955	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AQ505_RS17960	COG1785	Belongs to the alkaline phosphatase family
AQ505_RS17965	COG0702	epimerase
AQ505_RS17970	COG4771	TonB-dependent receptor
AQ505_RS17980	COG1595	DNA-templated transcription, initiation
AQ505_RS17985	COG0698	ribose 5-phosphate isomerase
AQ505_RS18010	COG0745	RESPONSE REGULATOR receiver
AQ505_RS18015	COG5002	protein histidine kinase activity
AQ505_RS18035	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AQ505_RS18050	COG0494	nUDIX hydrolase
AQ505_RS18065	COG0501	Belongs to the peptidase M48B family
AQ505_RS18085	COG0596	Alpha beta hydrolase
AQ505_RS18085	COG2226	methyltransferase
AQ505_RS18085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AQ505_RS18095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AQ505_RS18105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AQ505_RS18115	COG0577	efflux transmembrane transporter activity
AQ505_RS18125	COG2814	Major facilitator Superfamily
AQ505_RS18155	COG3685	Protein conserved in bacteria
AQ505_RS18165	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AQ505_RS18175	COG0351	phosphomethylpyrimidine kinase
AQ505_RS18180	COG0352	thiamine-phosphate diphosphorylase activity
AQ505_RS18185	COG2022	thiamine diphosphate biosynthetic process
AQ505_RS18190	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AQ505_RS18195	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AQ505_RS18205	COG1131	(ABC) transporter
AQ505_RS18210	COG2996	Protein conserved in bacteria
AQ505_RS18215	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AQ505_RS18230	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AQ505_RS18250	COG3278	Belongs to the heme-copper respiratory oxidase family
AQ505_RS18255	COG2010	Cytochrome c
AQ505_RS18280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AQ505_RS18295	COG3850	Histidine kinase
AQ505_RS18295	COG5002	protein histidine kinase activity
AQ505_RS18320	COG0702	epimerase
AQ505_RS18325	COG4771	TonB-dependent receptor
AQ505_RS18345	COG1858	cytochrome C peroxidase
AQ505_RS18355	COG1858	cytochrome C peroxidase
AQ505_RS18370	COG1999	signal sequence binding
AQ505_RS18385	COG1607	acyl-coa hydrolase
AQ505_RS18390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AQ505_RS18395	COG5002	protein histidine kinase activity
AQ505_RS18400	COG2205	protein histidine kinase activity
AQ505_RS18415	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AQ505_RS18420	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AQ505_RS18425	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AQ505_RS18430	COG2204	response regulator
AQ505_RS18445	COG1999	signal sequence binding
AQ505_RS18480	COG0038	chloride channel
AQ505_RS18490	COG0745	RESPONSE REGULATOR receiver
AQ505_RS18495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AQ505_RS18500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AQ505_RS18505	COG2207	Transcriptional regulator
AQ505_RS18545	COG4771	TonB-dependent receptor
AQ505_RS18550	COG4558	Periplasmic binding protein
AQ505_RS18555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AQ505_RS18560	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AQ505_RS18565	COG3720	iron ion transport
AQ505_RS18575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AQ505_RS18630	COG2072	flavoprotein involved in K transport
AQ505_RS18655	COG2186	Transcriptional regulator
AQ505_RS18690	COG3781	membrane
AQ505_RS18700	COG1131	(ABC) transporter
AQ505_RS18740	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AQ505_RS18750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AQ505_RS18755	COG2814	Major facilitator Superfamily
AQ505_RS18765	COG1309	transcriptional regulator
AQ505_RS18795	COG3537	Alpha-1,2-mannosidase
AQ505_RS18805	COG1629	transport
AQ505_RS18820	COG1629	transport
AQ505_RS18820	COG4206	TonB-dependent receptor
AQ505_RS18840	COG1045	serine acetyltransferase
AQ505_RS18855	COG1278	Cold shock
AQ505_RS18880	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AQ505_RS18880	COG0392	lysyltransferase activity
AQ505_RS18890	COG1733	regulation of RNA biosynthetic process
AQ505_RS18915	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AQ505_RS18950	COG2217	Heavy metal translocating P-type atpase
AQ505_RS18985	COG4771	TonB-dependent receptor
AQ505_RS19015	COG3275	phosphorelay sensor kinase activity
AQ505_RS19020	COG3279	Response regulator of the LytR AlgR family
AQ505_RS19090	COG0346	lactoylglutathione lyase activity
AQ505_RS19100	COG1741	Belongs to the pirin family
AQ505_RS19115	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AQ505_RS19120	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AQ505_RS19125	COG0363	glucosamine-6-phosphate deaminase activity
AQ505_RS19145	COG0644	oxidoreductase
AQ505_RS19160	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AQ505_RS19165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AQ505_RS19170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AQ505_RS19185	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AQ505_RS19200	COG1666	GTP binding
AQ505_RS19215	COG4172	Belongs to the ABC transporter superfamily
AQ505_RS19225	COG0557	exoribonuclease II activity
AQ505_RS19235	COG4565	transcriptional regulatory protein
AQ505_RS19245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AQ505_RS19250	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AQ505_RS19260	COG1301	dicarboxylic acid transport
AQ505_RS19265	COG1595	DNA-templated transcription, initiation
AQ505_RS19280	COG2207	Transcriptional regulator
AQ505_RS19290	COG2205	protein histidine kinase activity
AQ505_RS19290	COG3292	Two component regulator propeller
AQ505_RS19290	COG0745	RESPONSE REGULATOR receiver
AQ505_RS19295	COG2197	response regulator
AQ505_RS19305	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AQ505_RS19310	COG0492	ferredoxin-NADP+ reductase activity
AQ505_RS19315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AQ505_RS19345	COG0517	IMP dehydrogenase activity
AQ505_RS19345	COG0516	GMP reductase activity
AQ505_RS19385	COG0793	Belongs to the peptidase S41A family
AQ505_RS19425	COG4977	sequence-specific DNA binding
AQ505_RS19425	COG1917	Cupin 2, conserved barrel domain protein
AQ505_RS19455	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AQ505_RS19470	COG3279	Response regulator of the LytR AlgR family
AQ505_RS19505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AQ505_RS19510	COG2264	protein methyltransferase activity
AQ505_RS19515	COG0149	triose-phosphate isomerase activity
AQ505_RS19525	COG0254	rRNA binding
AQ505_RS19535	COG0346	lactoylglutathione lyase activity
AQ505_RS19540	COG1104	cysteine desulfurase activity
AQ505_RS19545	COG0822	iron-sulfur transferase activity
AQ505_RS19550	COG0316	Belongs to the HesB IscA family
AQ505_RS19555	COG1022	Amp-dependent synthetase and ligase
AQ505_RS19560	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AQ505_RS19580	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AQ505_RS19590	COG1321	iron dependent repressor
AQ505_RS19590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AQ505_RS19600	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AQ505_RS19605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AQ505_RS19610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AQ505_RS19615	COG2363	Small membrane protein
AQ505_RS19635	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AQ505_RS19640	COG0594	ribonuclease P activity
AQ505_RS19645	COG3279	Response regulator of the LytR AlgR family
AQ505_RS19650	COG3275	phosphorelay sensor kinase activity
AQ505_RS19665	COG1970	mechanosensitive ion channel activity
AQ505_RS19670	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AQ505_RS19675	COG2204	response regulator
AQ505_RS19680	COG2204	response regulator
AQ505_RS19695	COG3852	Histidine kinase
AQ505_RS19700	COG2204	response regulator
AQ505_RS19705	COG2201	protein-glutamate methylesterase activity
AQ505_RS19710	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AQ505_RS19715	COG4206	TonB-dependent receptor
AQ505_RS19720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AQ505_RS19740	COG5002	protein histidine kinase activity
AQ505_RS19750	COG1113	amino acid transport
AQ505_RS19765	COG3258	Cytochrome c
AQ505_RS19780	COG4251	negative regulation of phosphorylation
AQ505_RS19785	COG0784	Response regulator, receiver
AQ505_RS19790	COG2205	protein histidine kinase activity
AQ505_RS19795	COG1192	Involved in chromosome partitioning
AQ505_RS19845	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS19855	COG2354	Protein conserved in bacteria
AQ505_RS19860	COG1733	regulation of RNA biosynthetic process
AQ505_RS19865	COG2249	NAD(P)H dehydrogenase (quinone) activity
AQ505_RS19880	COG1280	lysine exporter protein (LysE YggA)
AQ505_RS19895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AQ505_RS19910	COG2897	thiosulfate sulfurtransferase activity
AQ505_RS19925	COG1349	DNA-binding transcription factor activity
AQ505_RS19930	COG2223	nitrite transmembrane transporter activity
AQ505_RS19965	COG0561	phosphatase activity
AQ505_RS19970	COG4771	TonB-dependent receptor
AQ505_RS19995	COG2205	protein histidine kinase activity
AQ505_RS19995	COG3292	Two component regulator propeller
AQ505_RS19995	COG0745	RESPONSE REGULATOR receiver
AQ505_RS19995	COG3292	Two component regulator propeller
AQ505_RS19995	COG0745	RESPONSE REGULATOR receiver
AQ505_RS19995	COG2205	protein histidine kinase activity
AQ505_RS20005	COG3537	Alpha-1,2-mannosidase
AQ505_RS20015	COG0702	epimerase
AQ505_RS20020	COG4771	TonB-dependent receptor
AQ505_RS20095	COG1629	transport
AQ505_RS20100	COG2814	Major facilitator Superfamily
AQ505_RS20110	COG2188	Transcriptional regulator
AQ505_RS20115	COG3537	Alpha-1,2-mannosidase
AQ505_RS20120	COG1472	Belongs to the glycosyl hydrolase 3 family
AQ505_RS20165	COG0702	epimerase
AQ505_RS20170	COG4771	TonB-dependent receptor
AQ505_RS20180	COG1609	Transcriptional regulator
AQ505_RS20205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AQ505_RS20240	COG4774	siderophore transport
AQ505_RS20275	COG5002	protein histidine kinase activity
AQ505_RS20275	COG2205	protein histidine kinase activity
AQ505_RS20275	COG0784	Response regulator, receiver
AQ505_RS20295	COG3279	Response regulator of the LytR AlgR family
AQ505_RS20300	COG2972	Histidine kinase
AQ505_RS20325	COG1011	Hydrolase
AQ505_RS20350	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AQ505_RS20355	COG1605	Chorismate mutase
AQ505_RS20355	COG0077	Prephenate dehydratase
AQ505_RS20360	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AQ505_RS20365	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AQ505_RS20370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AQ505_RS20385	COG0436	Aminotransferase
AQ505_RS20510	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AQ505_RS20525	COG0531	amino acid
AQ505_RS20535	COG1629	transport
AQ505_RS20550	COG1595	DNA-templated transcription, initiation
AQ505_RS20575	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AQ505_RS20585	COG4977	sequence-specific DNA binding
AQ505_RS20595	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AQ505_RS20610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AQ505_RS20615	COG0494	nUDIX hydrolase
AQ505_RS20620	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AQ505_RS20640	COG0542	response to heat
AQ505_RS20655	COG2223	nitrite transmembrane transporter activity
AQ505_RS20660	COG0438	transferase activity, transferring glycosyl groups
AQ505_RS20670	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AQ505_RS20700	COG1649	PFAM Uncharacterised BCR, COG1649
AQ505_RS20700	COG0726	polysaccharide deacetylase
AQ505_RS20710	COG0778	Nitroreductase
AQ505_RS20720	COG0488	(ABC) transporter
AQ505_RS20735	COG1136	(ABC) transporter
AQ505_RS20740	COG0577	efflux transmembrane transporter activity
AQ505_RS20750	COG0735	belongs to the Fur family
AQ505_RS20770	COG1629	transport
AQ505_RS20770	COG4206	TonB-dependent receptor
AQ505_RS20790	COG4948	Mandelate Racemase Muconate Lactonizing
AQ505_RS20800	COG3757	hydrolase, family 25
AQ505_RS20835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AQ505_RS20845	COG0758	DNA mediated transformation
AQ505_RS20850	COG0357	Ribosomal RNA small subunit methyltransferase G
AQ505_RS20860	COG0343	queuine tRNA-ribosyltransferase activity
AQ505_RS20895	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AQ505_RS20900	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AQ505_RS20905	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AQ505_RS20910	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AQ505_RS20940	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AQ505_RS20960	COG1104	cysteine desulfurase activity
AQ505_RS20965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AQ505_RS20970	COG2226	methyltransferase
AQ505_RS20990	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AQ505_RS20995	COG0237	dephospho-CoA kinase activity
AQ505_RS21005	COG1862	Preprotein translocase
AQ505_RS21015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AQ505_RS21025	COG1132	(ABC) transporter
AQ505_RS21035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AQ505_RS21050	COG1629	transport
AQ505_RS21050	COG4206	TonB-dependent receptor
AQ505_RS21085	COG1271	oxidase subunit
AQ505_RS21120	COG2259	Doxx family
AQ505_RS21140	COG3279	Response regulator of the LytR AlgR family
AQ505_RS21150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AQ505_RS21155	COG3250	beta-galactosidase activity
AQ505_RS21175	COG4771	TonB-dependent receptor
AQ505_RS21180	COG0702	epimerase
AQ505_RS21185	COG1629	transport
AQ505_RS21190	COG2205	protein histidine kinase activity
AQ505_RS21190	COG0745	RESPONSE REGULATOR receiver
AQ505_RS21190	COG3292	Two component regulator propeller
AQ505_RS21200	COG0494	nUDIX hydrolase
AQ505_RS21205	COG0587	DNA-directed DNA polymerase activity
AQ505_RS21230	COG3123	guanosine phosphorylase activity
AQ505_RS21235	COG0484	heat shock protein binding
AQ505_RS21240	COG0745	RESPONSE REGULATOR receiver
AQ505_RS21245	COG2205	protein histidine kinase activity
AQ505_RS21285	COG0012	GTP binding
AQ505_RS21290	COG2239	Acts as a magnesium transporter
AQ505_RS21310	COG1917	Cupin 2, conserved barrel domain protein
AQ505_RS21310	COG2207	Transcriptional regulator
AQ505_RS21320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AQ505_RS21330	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AQ505_RS21345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AQ505_RS21360	COG0167	dihydroorotate dehydrogenase activity
AQ505_RS21365	COG0488	(ABC) transporter
AQ505_RS21375	COG0366	Alpha amylase catalytic
AQ505_RS21380	COG1607	acyl-coa hydrolase
AQ505_RS21435	COG2076	Multidrug Resistance protein
AQ505_RS21455	COG0525	valine-tRNA ligase activity
AQ505_RS21460	COG0823	Involved in the tonB-independent uptake of proteins
AQ505_RS21460	COG1506	peptidase
AQ505_RS21470	COG0702	epimerase
AQ505_RS21475	COG1629	transport
AQ505_RS21500	COG3590	peptidase
AQ505_RS21505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AQ505_RS21505	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AQ505_RS21510	COG0667	Aldo Keto reductase
AQ505_RS21515	COG0628	permease
AQ505_RS21525	COG3956	TIGRFAM MazG family protein
AQ505_RS21540	COG1132	(ABC) transporter
AQ505_RS21545	COG1132	(ABC) transporter
AQ505_RS21550	COG4591	ABC-type transport system involved in lipoprotein release permease component
AQ505_RS21555	COG3876	Protein conserved in bacteria
AQ505_RS21570	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AQ505_RS21580	COG0564	pseudouridine synthase activity
AQ505_RS21585	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AQ505_RS21595	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AQ505_RS21630	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AQ505_RS21645	COG1960	acyl-CoA dehydrogenase activity
AQ505_RS21650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AQ505_RS21655	COG0386	Belongs to the glutathione peroxidase family
AQ505_RS21665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AQ505_RS21675	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AQ505_RS21690	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AQ505_RS21705	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AQ505_RS21730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AQ505_RS21745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AQ505_RS21750	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AQ505_RS21790	COG0745	RESPONSE REGULATOR receiver
AQ505_RS21795	COG5002	protein histidine kinase activity
AQ505_RS21815	COG2153	protein acetylation
AQ505_RS21835	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AQ505_RS21875	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AQ505_RS21880	COG3011	Protein conserved in bacteria
AQ505_RS21885	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AQ505_RS21890	COG0540	Belongs to the ATCase OTCase family
AQ505_RS21910	COG0811	peptide transport
AQ505_RS21935	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AQ505_RS21935	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AQ505_RS21935	COG1703	isobutyryl-CoA mutase activity
AQ505_RS21980	COG3347	Dehydrogenase
AQ505_RS21980	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS22000	COG3940	Belongs to the glycosyl hydrolase 43 family
AQ505_RS22005	COG3408	Glycogen debranching enzyme
AQ505_RS22010	COG3408	Glycogen debranching enzyme
AQ505_RS22080	COG1725	Transcriptional regulator
AQ505_RS22090	COG1131	(ABC) transporter
AQ505_RS22100	COG1472	Belongs to the glycosyl hydrolase 3 family
AQ505_RS22135	COG0497	DNA recombination
AQ505_RS22150	COG3622	Belongs to the hyi family
AQ505_RS22155	COG1477	protein flavinylation
AQ505_RS22160	COG0673	inositol 2-dehydrogenase activity
AQ505_RS22165	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AQ505_RS22175	COG0488	(ABC) transporter
AQ505_RS22180	COG0542	response to heat
AQ505_RS22220	COG0513	Belongs to the DEAD box helicase family
AQ505_RS22245	COG0004	ammonium transporteR
AQ505_RS22255	COG1242	4 iron, 4 sulfur cluster binding
AQ505_RS22270	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AQ505_RS22285	COG1309	transcriptional regulator
AQ505_RS22290	COG4772	TonB-dependent receptor
AQ505_RS22305	COG2195	Cleaves the N-terminal amino acid of tripeptides
AQ505_RS22315	COG1629	transport
AQ505_RS22325	COG1191	sigma factor activity
AQ505_RS22335	COG4133	protoheme IX ABC transporter activity
AQ505_RS22350	COG2610	gluconate transmembrane transporter activity
AQ505_RS22355	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AQ505_RS22365	COG1349	DNA-binding transcription factor activity
AQ505_RS22385	COG0589	response to stress
AQ505_RS22420	COG0531	amino acid
AQ505_RS22425	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AQ505_RS22430	COG0531	amino acid
AQ505_RS22435	COG2095	MarC family integral membrane protein
AQ505_RS22440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AQ505_RS22440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AQ505_RS22450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AQ505_RS22450	COG0519	Catalyzes the synthesis of GMP from XMP
AQ505_RS22480	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AQ505_RS22500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AQ505_RS22510	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AQ505_RS22525	COG1610	YqeY-like protein
AQ505_RS22530	COG4221	oxidoreductase activity
AQ505_RS22540	COG2226	methyltransferase
AQ505_RS22545	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AQ505_RS22550	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AQ505_RS22560	COG0531	amino acid
AQ505_RS22570	COG3158	transport of potassium into the cell
AQ505_RS22580	COG0179	Fumarylacetoacetate (FAA) hydrolase
AQ505_RS22590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AQ505_RS22595	COG2205	protein histidine kinase activity
AQ505_RS22595	COG0784	Response regulator, receiver
AQ505_RS22615	COG1595	DNA-templated transcription, initiation
AQ505_RS22630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AQ505_RS22640	COG3118	belongs to the thioredoxin family
AQ505_RS22665	COG0187	DNA topoisomerase II activity
AQ505_RS22675	COG0590	tRNA wobble adenosine to inosine editing
AQ505_RS22685	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AQ505_RS22690	COG2171	N-acyltransferase activity
AQ505_RS22695	COG0438	transferase activity, transferring glycosyl groups
AQ505_RS22700	COG0009	L-threonylcarbamoyladenylate synthase
AQ505_RS22705	COG0617	tRNA 3'-terminal CCA addition
AQ505_RS22705	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AQ505_RS22705	COG0517	IMP dehydrogenase activity
AQ505_RS22715	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AQ505_RS22725	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AQ505_RS22730	COG0085	RNA polymerase activity
AQ505_RS22735	COG0222	ribosome binding
AQ505_RS22740	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AQ505_RS22745	COG0081	regulation of translation
AQ505_RS22750	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AQ505_RS22800	COG4974	Belongs to the 'phage' integrase family
AQ505_RS22805	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AQ505_RS22815	COG1960	acyl-CoA dehydrogenase activity
AQ505_RS22830	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AQ505_RS22870	COG1418	mRNA catabolic process
AQ505_RS22895	COG2003	Belongs to the UPF0758 family
AQ505_RS22900	COG0268	Binds directly to 16S ribosomal RNA
AQ505_RS22905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AQ505_RS22910	COG0138	bifunctional purine biosynthesis protein purh
AQ505_RS22915	COG1077	Cell shape determining protein MreB Mrl
AQ505_RS22930	COG0768	penicillin binding
AQ505_RS22935	COG0772	Belongs to the SEDS family
AQ505_RS22955	COG3250	beta-galactosidase activity
AQ505_RS22970	COG0702	epimerase
AQ505_RS22975	COG1629	transport
AQ505_RS22980	COG0702	epimerase
AQ505_RS22985	COG1629	transport
AQ505_RS22990	COG3292	Two component regulator propeller
AQ505_RS22990	COG2205	protein histidine kinase activity
AQ505_RS22990	COG0745	RESPONSE REGULATOR receiver
AQ505_RS23010	COG4206	TonB-dependent receptor
AQ505_RS23010	COG1629	transport
AQ505_RS23030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AQ505_RS23060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AQ505_RS23080	COG2181	nitrate reductase activity
AQ505_RS23080	COG0247	lactate metabolic process
AQ505_RS23085	COG0247	lactate metabolic process
AQ505_RS23085	COG2181	nitrate reductase activity
AQ505_RS23090	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AQ505_RS23105	COG1446	asparaginase
AQ505_RS23110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AQ505_RS23115	COG0359	binds to the 23S rRNA
AQ505_RS23120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AQ505_RS23125	COG0360	Binds together with S18 to 16S ribosomal RNA
AQ505_RS23140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AQ505_RS23150	COG4774	siderophore transport
AQ505_RS23155	COG0629	single-stranded DNA binding
AQ505_RS23170	COG2910	NAD(P)H-binding
AQ505_RS23200	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AQ505_RS23210	COG4771	TonB-dependent receptor
AQ505_RS23215	COG0702	epimerase
AQ505_RS23220	COG1472	Belongs to the glycosyl hydrolase 3 family
AQ505_RS23235	COG0564	pseudouridine synthase activity
AQ505_RS23240	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AQ505_RS23245	COG0505	Belongs to the CarA family
AQ505_RS23250	COG1131	(ABC) transporter
AQ505_RS23260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AQ505_RS23275	COG2860	membrane
AQ505_RS23285	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS23300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AQ505_RS23300	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AQ505_RS23310	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AQ505_RS23315	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AQ505_RS23320	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AQ505_RS23330	COG1132	(ABC) transporter
AQ505_RS23335	COG0101	tRNA pseudouridine synthase activity
AQ505_RS23360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AQ505_RS23370	COG0726	polysaccharide deacetylase
AQ505_RS23385	COG2723	6-phospho-beta-galactosidase activity
AQ505_RS23390	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AQ505_RS23395	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AQ505_RS23405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AQ505_RS23420	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AQ505_RS23425	COG1663	tetraacyldisaccharide 4'-kinase activity
AQ505_RS23430	COG1012	belongs to the aldehyde dehydrogenase family
AQ505_RS23435	COG0288	reversible hydration of carbon dioxide
AQ505_RS23440	COG0659	secondary active sulfate transmembrane transporter activity
AQ505_RS23455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AQ505_RS23460	COG2814	Major facilitator Superfamily
AQ505_RS23470	COG1363	Peptidase, m42
AQ505_RS23475	COG0433	COG0433 Predicted ATPase
AQ505_RS23485	COG0443	Heat shock 70 kDa protein
AQ505_RS23500	COG0203	ribosomal protein L17
AQ505_RS23505	COG0202	RNA polymerase activity
AQ505_RS23510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AQ505_RS23515	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AQ505_RS23520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AQ505_RS23525	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AQ505_RS23530	COG0024	Methionine aminopeptidase
AQ505_RS23535	COG0201	protein transport
AQ505_RS23540	COG0200	Binds to the 23S rRNA
AQ505_RS23545	COG1841	ribosomal large subunit assembly
AQ505_RS23550	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AQ505_RS23555	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AQ505_RS23560	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AQ505_RS23565	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AQ505_RS23570	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AQ505_RS23575	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AQ505_RS23580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AQ505_RS23585	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AQ505_RS23590	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AQ505_RS23595	COG0255	Belongs to the universal ribosomal protein uL29 family
AQ505_RS23600	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AQ505_RS23605	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AQ505_RS23610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AQ505_RS23615	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AQ505_RS23620	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AQ505_RS23625	COG0089	rRNA binding
AQ505_RS23630	COG0088	Forms part of the polypeptide exit tunnel
AQ505_RS23635	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AQ505_RS23645	COG0730	response to heat
AQ505_RS23655	COG0051	transcription antitermination factor activity, RNA binding
AQ505_RS23660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AQ505_RS23665	COG0049	tRNA binding
AQ505_RS23670	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AQ505_RS23675	COG4628	conserved protein (DUF2132)
AQ505_RS23690	COG0668	transmembrane transport
AQ505_RS23705	COG1393	Belongs to the ArsC family
AQ505_RS23715	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AQ505_RS23720	COG0784	Response regulator, receiver
AQ505_RS23720	COG2205	protein histidine kinase activity
AQ505_RS23725	COG0193	aminoacyl-tRNA hydrolase activity
AQ505_RS23730	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AQ505_RS23735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AQ505_RS23750	COG0825	malonyl-CoA metabolic process
AQ505_RS23770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AQ505_RS23775	COG0366	Alpha amylase catalytic
AQ505_RS23790	COG1629	transport
AQ505_RS23790	COG4206	TonB-dependent receptor
AQ505_RS23795	COG1609	Transcriptional regulator
AQ505_RS23800	COG3239	Fatty acid desaturase
AQ505_RS23810	COG0584	glycerophosphoryl diester phosphodiesterase
AQ505_RS23815	COG1349	DNA-binding transcription factor activity
AQ505_RS23845	COG0142	geranyltranstransferase activity
AQ505_RS23855	COG0492	ferredoxin-NADP+ reductase activity
AQ505_RS23860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AQ505_RS23860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AQ505_RS23865	COG0252	asparaginase activity
AQ505_RS23870	COG0084	hydrolase, TatD family'
AQ505_RS23885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AQ505_RS23890	COG0105	UTP biosynthetic process
AQ505_RS23895	COG0545	Peptidyl-prolyl cis-trans isomerase
AQ505_RS23910	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AQ505_RS23920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AQ505_RS23935	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AQ505_RS23940	COG1595	DNA-templated transcription, initiation
AQ505_RS23950	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AQ505_RS23950	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AQ505_RS23955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AQ505_RS23970	COG1187	pseudouridine synthase activity
AQ505_RS23975	COG2706	6-phosphogluconolactonase activity
AQ505_RS23980	COG0438	transferase activity, transferring glycosyl groups
AQ505_RS23990	COG0037	tRNA processing
AQ505_RS24000	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AQ505_RS24015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AQ505_RS24020	COG0714	Associated with various cellular activities
AQ505_RS24025	COG0584	glycerophosphoryl diester phosphodiesterase
AQ505_RS24035	COG0215	cysteine-tRNA ligase activity
AQ505_RS24055	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AQ505_RS24060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AQ505_RS24075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AQ505_RS24080	COG3015	lipoprotein NlpE involved in copper resistance
AQ505_RS24095	COG0778	Nitroreductase
AQ505_RS24120	COG4771	TonB-dependent receptor
AQ505_RS24140	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AQ505_RS24145	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AQ505_RS24150	COG1381	Involved in DNA repair and RecF pathway recombination
AQ505_RS24175	COG4335	DNA alkylation repair
AQ505_RS24205	COG2133	pyrroloquinoline quinone binding
AQ505_RS24215	COG3511	phospholipase C
AQ505_RS24225	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AQ505_RS24230	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AQ505_RS24235	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AQ505_RS24250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AQ505_RS24255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AQ505_RS24265	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AQ505_RS24270	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AQ505_RS24270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AQ505_RS24290	COG2045	Belongs to the ComB family
AQ505_RS24295	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AQ505_RS24305	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AQ505_RS24310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AQ505_RS24325	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AQ505_RS24340	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AQ505_RS24345	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AQ505_RS24350	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AQ505_RS24355	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AQ505_RS24360	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AQ505_RS24365	COG0356	it plays a direct role in the translocation of protons across the membrane
AQ505_RS24385	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AQ505_RS24390	COG0322	excinuclease ABC activity
AQ505_RS24410	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AQ505_RS24425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AQ505_RS24430	COG4221	oxidoreductase activity
AQ505_RS24440	COG3250	beta-galactosidase activity
AQ505_RS24450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AQ505_RS24465	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AQ505_RS24490	COG1408	metallophosphoesterase
AQ505_RS24500	COG0745	RESPONSE REGULATOR receiver
AQ505_RS24530	COG1360	Flagellar Motor Protein
AQ505_RS24550	COG2322	membrane
AQ505_RS24555	COG1999	signal sequence binding
AQ505_RS24565	COG1845	cytochrome c oxidase, subunit III
AQ505_RS24570	COG1845	cytochrome c oxidase, subunit III
AQ505_RS24575	COG0109	protoheme IX farnesyltransferase activity
AQ505_RS24580	COG1612	heme a metabolic process
AQ505_RS24585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AQ505_RS24615	COG0437	4 iron, 4 sulfur cluster binding
AQ505_RS24645	COG0657	acetylesterase activity
AQ505_RS24645	COG2755	lipolytic protein G-D-S-L family
AQ505_RS24650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AQ505_RS24660	COG1473	amidohydrolase
AQ505_RS24680	COG0792	nuclease activity
AQ505_RS24685	COG0358	DNA primase activity
AQ505_RS24705	COG1473	amidohydrolase
AQ505_RS24715	COG0653	protein targeting
AQ505_RS24730	COG0151	Belongs to the GarS family
AQ505_RS24760	COG1696	Membrane protein involved in D-alanine export
AQ505_RS24775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AQ505_RS24780	COG0010	Belongs to the arginase family
AQ505_RS24785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AQ505_RS24795	COG3483	tryptophan 2,3-dioxygenase activity
AQ505_RS24800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AQ505_RS24875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AQ505_RS24880	COG2204	response regulator
AQ505_RS24900	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AQ505_RS24905	COG0459	protein refolding
AQ505_RS24910	COG1285	pathogenesis
AQ505_RS24915	COG1760	l-serine dehydratase
AQ505_RS24935	COG0321	lipoyl(octanoyl) transferase activity
AQ505_RS24950	COG1629	transport
AQ505_RS24960	COG1028	Short-chain dehydrogenase reductase Sdr
AQ505_RS24970	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AQ505_RS24985	COG0494	nUDIX hydrolase
AQ505_RS24995	COG3279	Response regulator of the LytR AlgR family
AQ505_RS25000	COG2972	Histidine kinase
AQ505_RS25020	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AQ505_RS25030	COG1053	succinate dehydrogenase
AQ505_RS25040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AQ505_RS25045	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AQ505_RS25050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AQ505_RS25055	COG3119	arylsulfatase activity
AQ505_RS25065	COG4771	TonB-dependent receptor
AQ505_RS25075	COG2197	response regulator
AQ505_RS25105	COG0116	Belongs to the methyltransferase superfamily
AQ505_RS25105	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AQ505_RS25115	COG1418	mRNA catabolic process
AQ505_RS25120	COG5002	protein histidine kinase activity
AQ505_RS25130	COG0306	phosphate transporter
AQ505_RS25145	COG2304	oxidoreductase activity
AQ505_RS25155	COG0513	Belongs to the DEAD box helicase family
AQ505_RS25160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AQ505_RS25170	COG1131	(ABC) transporter
AQ505_RS25185	COG0673	inositol 2-dehydrogenase activity
AQ505_RS25190	COG3228	Belongs to the MtfA family
AQ505_RS25195	COG2267	carboxylic ester hydrolase activity
AQ505_RS25200	COG2986	histidine ammonia-lyase
AQ505_RS25205	COG4771	TonB-dependent receptor
AQ505_RS25210	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AQ505_RS25220	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AQ505_RS25225	COG0702	epimerase
AQ505_RS25230	COG0745	RESPONSE REGULATOR receiver
AQ505_RS25240	COG0124	histidyl-tRNA synthetase
AQ505_RS25245	COG0508	dehydrogenase complex catalyzes the overall conversion of
AQ505_RS25250	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AQ505_RS25255	COG0791	NLP P60 protein
AQ505_RS25285	COG1446	asparaginase
AQ505_RS25305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AQ505_RS25325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AQ505_RS25330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AQ505_RS25340	COG0251	oxidation-reduction process
AQ505_RS25355	COG0463	Glycosyl transferase, family 2
AQ505_RS25365	COG1132	(ABC) transporter
AQ505_RS25375	COG1216	Glycosyl transferase, family 2
AQ505_RS25420	COG5180	pathogenesis
AQ505_RS25420	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AQ505_RS25425	COG0195	Participates in both transcription termination and antitermination
AQ505_RS25430	COG0779	Required for maturation of 30S ribosomal subunits
AQ505_RS25445	COG1960	acyl-CoA dehydrogenase activity
AQ505_RS25450	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AQ505_RS25460	COG0297	glycogen (starch) synthase activity
AQ505_RS25470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AQ505_RS25480	COG1194	a g-specific adenine glycosylase
AQ505_RS25485	COG0776	regulation of translation
AQ505_RS25495	COG1530	ribonuclease E activity
AQ505_RS25500	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AQ505_RS25510	COG1704	LemA family
AQ505_RS25515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AQ505_RS25545	COG0352	thiamine-phosphate diphosphorylase activity
AQ505_RS25555	COG1132	(ABC) transporter
AQ505_RS25560	COG0233	cytoplasmic translational termination
AQ505_RS25565	COG0528	UMP kinase activity
AQ505_RS25570	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AQ505_RS25630	COG0720	synthase
AQ505_RS25635	COG1612	heme a metabolic process
AQ505_RS25640	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AQ505_RS25645	COG0052	Belongs to the universal ribosomal protein uS2 family
AQ505_RS25650	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AQ505_RS25670	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AQ505_RS25675	COG2226	methyltransferase
AQ505_RS25680	COG2195	Cleaves the N-terminal amino acid of tripeptides
AQ505_RS25700	COG4948	Mandelate Racemase Muconate Lactonizing
AQ505_RS25755	COG4206	TonB-dependent receptor
AQ505_RS25755	COG1629	transport
AQ505_RS25765	COG4191	Histidine kinase
AQ505_RS25770	COG2204	response regulator
AQ505_RS25780	COG0577	efflux transmembrane transporter activity
AQ505_RS25785	COG1136	(ABC) transporter
AQ505_RS25800	COG1070	Carbohydrate kinase
AQ505_RS25820	COG4771	TonB-dependent receptor
AQ505_RS25845	COG3275	phosphorelay sensor kinase activity
AQ505_RS25850	COG3279	Response regulator of the LytR AlgR family
AQ505_RS25855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AQ505_RS25890	COG0657	acetylesterase activity
AQ505_RS25895	COG2249	NAD(P)H dehydrogenase (quinone) activity