locus-tag	class	description
H9N25_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H9N25_RS00010	COG0494	nUDIX hydrolase
H9N25_RS00035	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
H9N25_RS00090	COG0726	polysaccharide deacetylase
H9N25_RS00095	COG0463	Glycosyl transferase, family 2
H9N25_RS00115	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H9N25_RS00125	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
H9N25_RS00140	COG2205	protein histidine kinase activity
H9N25_RS00145	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS00175	COG2378	regulation of single-species biofilm formation
H9N25_RS00185	COG1733	regulation of RNA biosynthetic process
H9N25_RS00190	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS00195	COG2909	trisaccharide binding
H9N25_RS00220	COG5002	protein histidine kinase activity
H9N25_RS00225	COG0745	RESPONSE REGULATOR receiver
H9N25_RS00255	COG3275	phosphorelay sensor kinase activity
H9N25_RS00260	COG3279	Response regulator of the LytR AlgR family
H9N25_RS00265	COG3118	belongs to the thioredoxin family
H9N25_RS00265	COG0492	ferredoxin-NADP+ reductase activity
H9N25_RS00375	COG0673	inositol 2-dehydrogenase activity
H9N25_RS00415	COG1629	transport
H9N25_RS00415	COG4206	TonB-dependent receptor
H9N25_RS00425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS00435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS00440	COG3279	Response regulator of the LytR AlgR family
H9N25_RS00445	COG3275	phosphorelay sensor kinase activity
H9N25_RS00470	COG1301	dicarboxylic acid transport
H9N25_RS00475	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H9N25_RS00480	COG1301	dicarboxylic acid transport
H9N25_RS00485	COG0579	oxidoreductase
H9N25_RS00500	COG1733	regulation of RNA biosynthetic process
H9N25_RS00505	COG4221	oxidoreductase activity
H9N25_RS00545	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
H9N25_RS00570	COG4206	TonB-dependent receptor
H9N25_RS00570	COG1629	transport
H9N25_RS00580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS00590	COG1846	Transcriptional regulator
H9N25_RS00590	COG0456	acetyltransferase
H9N25_RS00615	COG0745	RESPONSE REGULATOR receiver
H9N25_RS00615	COG2205	protein histidine kinase activity
H9N25_RS00615	COG3292	Two component regulator propeller
H9N25_RS00620	COG3292	Two component regulator propeller
H9N25_RS00620	COG2205	protein histidine kinase activity
H9N25_RS00620	COG0745	RESPONSE REGULATOR receiver
H9N25_RS00625	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H9N25_RS00630	COG4771	TonB-dependent receptor
H9N25_RS00635	COG0702	epimerase
H9N25_RS00650	COG3119	arylsulfatase activity
H9N25_RS00700	COG1733	regulation of RNA biosynthetic process
H9N25_RS00725	COG0673	inositol 2-dehydrogenase activity
H9N25_RS00730	COG0464	growth
H9N25_RS00815	COG0582	viral genome integration into host DNA
H9N25_RS00830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9N25_RS00830	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9N25_RS00840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H9N25_RS00855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9N25_RS00860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9N25_RS00870	COG2132	Multicopper oxidase
H9N25_RS00895	COG2814	Major facilitator Superfamily
H9N25_RS00935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9N25_RS00985	COG3292	Two component regulator propeller
H9N25_RS00985	COG0745	RESPONSE REGULATOR receiver
H9N25_RS00985	COG2205	protein histidine kinase activity
H9N25_RS00990	COG1629	transport
H9N25_RS00995	COG0702	epimerase
H9N25_RS01005	COG5492	domain, Protein
H9N25_RS01010	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H9N25_RS01020	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
H9N25_RS01025	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS01030	COG0288	reversible hydration of carbon dioxide
H9N25_RS01100	COG4771	TonB-dependent receptor
H9N25_RS01105	COG0702	epimerase
H9N25_RS01120	COG1733	regulation of RNA biosynthetic process
H9N25_RS01145	COG4771	TonB-dependent receptor
H9N25_RS01150	COG0702	epimerase
H9N25_RS01180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS01185	COG4771	TonB-dependent receptor
H9N25_RS01205	COG3507	Belongs to the glycosyl hydrolase 43 family
H9N25_RS01210	COG2382	esterase
H9N25_RS01230	COG3693	PFAM glycoside hydrolase, family 10
H9N25_RS01230	COG3507	Belongs to the glycosyl hydrolase 43 family
H9N25_RS01230	COG2382	esterase
H9N25_RS01240	COG1082	Xylose isomerase domain protein TIM barrel
H9N25_RS01245	COG3661	Belongs to the glycosyl hydrolase 67 family
H9N25_RS01250	COG3507	Belongs to the glycosyl hydrolase 43 family
H9N25_RS01265	COG0745	RESPONSE REGULATOR receiver
H9N25_RS01265	COG3292	Two component regulator propeller
H9N25_RS01265	COG2205	protein histidine kinase activity
H9N25_RS01275	COG4771	TonB-dependent receptor
H9N25_RS01285	COG4771	TonB-dependent receptor
H9N25_RS01305	COG3507	Belongs to the glycosyl hydrolase 43 family
H9N25_RS01315	COG1629	transport
H9N25_RS01355	COG4771	TonB-dependent receptor
H9N25_RS01365	COG1629	transport
H9N25_RS01370	COG4771	TonB-dependent receptor
H9N25_RS01375	COG0702	epimerase
H9N25_RS01390	COG4948	Mandelate Racemase Muconate Lactonizing
H9N25_RS01400	COG0745	RESPONSE REGULATOR receiver
H9N25_RS01400	COG3292	Two component regulator propeller
H9N25_RS01400	COG2205	protein histidine kinase activity
H9N25_RS01405	COG2205	protein histidine kinase activity
H9N25_RS01405	COG0745	RESPONSE REGULATOR receiver
H9N25_RS01405	COG3292	Two component regulator propeller
H9N25_RS01410	COG1595	DNA-templated transcription, initiation
H9N25_RS01450	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
H9N25_RS01455	COG4771	TonB-dependent receptor
H9N25_RS01460	COG0702	epimerase
H9N25_RS01480	COG4166	transmembrane transport
H9N25_RS01490	COG2204	response regulator
H9N25_RS01500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9N25_RS01510	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9N25_RS01535	COG4335	DNA alkylation repair
H9N25_RS01540	COG2084	Dehydrogenase
H9N25_RS01550	COG2204	response regulator
H9N25_RS01580	COG2610	gluconate transmembrane transporter activity
H9N25_RS01595	COG4181	ATPase activity
H9N25_RS01605	COG1858	cytochrome C peroxidase
H9N25_RS01675	COG0702	epimerase
H9N25_RS01680	COG4771	TonB-dependent receptor
H9N25_RS01690	COG4771	TonB-dependent receptor
H9N25_RS01735	COG4191	Histidine kinase
H9N25_RS01740	COG0745	RESPONSE REGULATOR receiver
H9N25_RS01770	COG3278	Belongs to the heme-copper respiratory oxidase family
H9N25_RS01800	COG2989	Protein conserved in bacteria
H9N25_RS01820	COG1629	transport
H9N25_RS01825	COG4771	TonB-dependent receptor
H9N25_RS01830	COG4771	TonB-dependent receptor
H9N25_RS01875	COG1609	Transcriptional regulator
H9N25_RS01910	COG3437	response regulator, receiver
H9N25_RS01915	COG3292	Two component regulator propeller
H9N25_RS01915	COG2205	protein histidine kinase activity
H9N25_RS01915	COG0745	RESPONSE REGULATOR receiver
H9N25_RS01920	COG4771	TonB-dependent receptor
H9N25_RS01940	COG3940	Belongs to the glycosyl hydrolase 43 family
H9N25_RS01960	COG3264	Mechanosensitive ion channel
H9N25_RS01960	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
H9N25_RS01970	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
H9N25_RS01975	COG4251	negative regulation of phosphorylation
H9N25_RS01980	COG4251	negative regulation of phosphorylation
H9N25_RS01985	COG5002	protein histidine kinase activity
H9N25_RS02000	COG3340	Belongs to the peptidase S51 family
H9N25_RS02015	COG0110	maltose O-acetyltransferase activity
H9N25_RS02030	COG0463	Glycosyl transferase, family 2
H9N25_RS02045	COG1216	Glycosyl transferase, family 2
H9N25_RS02055	COG0438	transferase activity, transferring glycosyl groups
H9N25_RS02075	COG0438	transferase activity, transferring glycosyl groups
H9N25_RS02085	COG0297	glycogen (starch) synthase activity
H9N25_RS02090	COG1216	Glycosyl transferase, family 2
H9N25_RS02120	COG1216	Glycosyl transferase, family 2
H9N25_RS02145	COG0438	transferase activity, transferring glycosyl groups
H9N25_RS02150	COG0367	asparagine synthase
H9N25_RS02160	COG0489	protein tyrosine kinase activity
H9N25_RS02185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9N25_RS02190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9N25_RS02240	COG0702	epimerase
H9N25_RS02255	COG2001	Belongs to the MraZ family
H9N25_RS02260	COG0275	rRNA processing
H9N25_RS02270	COG0768	penicillin binding
H9N25_RS02275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9N25_RS02280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9N25_RS02285	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H9N25_RS02290	COG0772	Belongs to the SEDS family
H9N25_RS02300	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H9N25_RS02305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9N25_RS02320	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H9N25_RS02325	COG0156	8-amino-7-oxononanoate synthase activity
H9N25_RS02355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9N25_RS02360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9N25_RS02375	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9N25_RS02390	COG3275	phosphorelay sensor kinase activity
H9N25_RS02400	COG0523	cobalamin synthesis protein
H9N25_RS02415	COG1136	(ABC) transporter
H9N25_RS02445	COG0735	belongs to the Fur family
H9N25_RS02475	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H9N25_RS02515	COG1349	DNA-binding transcription factor activity
H9N25_RS02535	COG0205	6-phosphofructokinase activity
H9N25_RS02565	COG3408	Glycogen debranching enzyme
H9N25_RS02655	COG0629	single-stranded DNA binding
H9N25_RS02730	COG0360	Binds together with S18 to 16S ribosomal RNA
H9N25_RS02735	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H9N25_RS02740	COG0359	binds to the 23S rRNA
H9N25_RS02745	COG4221	oxidoreductase activity
H9N25_RS02755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9N25_RS02790	COG2181	nitrate reductase activity
H9N25_RS02790	COG0247	lactate metabolic process
H9N25_RS02795	COG0247	lactate metabolic process
H9N25_RS02795	COG2181	nitrate reductase activity
H9N25_RS02835	COG2972	Histidine kinase
H9N25_RS02840	COG3279	Response regulator of the LytR AlgR family
H9N25_RS02870	COG3347	Dehydrogenase
H9N25_RS02870	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS02875	COG4952	isomerase
H9N25_RS02880	COG1070	Carbohydrate kinase
H9N25_RS02895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9N25_RS02910	COG1435	thymidine kinase activity
H9N25_RS02920	COG0772	Belongs to the SEDS family
H9N25_RS02925	COG0768	penicillin binding
H9N25_RS02940	COG1077	Cell shape determining protein MreB Mrl
H9N25_RS02945	COG0138	bifunctional purine biosynthesis protein purh
H9N25_RS02950	COG1733	regulation of RNA biosynthetic process
H9N25_RS02955	COG0477	Major facilitator Superfamily
H9N25_RS02960	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H9N25_RS02965	COG0268	Binds directly to 16S ribosomal RNA
H9N25_RS02970	COG2003	Belongs to the UPF0758 family
H9N25_RS02985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H9N25_RS03015	COG1418	mRNA catabolic process
H9N25_RS03070	COG1960	acyl-CoA dehydrogenase activity
H9N25_RS03085	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H9N25_RS03090	COG4974	Belongs to the 'phage' integrase family
H9N25_RS03140	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H9N25_RS03145	COG0081	regulation of translation
H9N25_RS03150	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H9N25_RS03155	COG0222	ribosome binding
H9N25_RS03160	COG0085	RNA polymerase activity
H9N25_RS03165	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9N25_RS03175	COG3119	arylsulfatase activity
H9N25_RS03195	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H9N25_RS03205	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H9N25_RS03205	COG0617	tRNA 3'-terminal CCA addition
H9N25_RS03205	COG0517	IMP dehydrogenase activity
H9N25_RS03210	COG0009	L-threonylcarbamoyladenylate synthase
H9N25_RS03220	COG0438	transferase activity, transferring glycosyl groups
H9N25_RS03225	COG2171	N-acyltransferase activity
H9N25_RS03240	COG3118	belongs to the thioredoxin family
H9N25_RS03245	COG0590	tRNA wobble adenosine to inosine editing
H9N25_RS03265	COG1695	Transcriptional regulator
H9N25_RS03280	COG3781	membrane
H9N25_RS03290	COG2205	protein histidine kinase activity
H9N25_RS03295	COG0745	RESPONSE REGULATOR receiver
H9N25_RS03320	COG0039	L-malate dehydrogenase activity
H9N25_RS03335	COG3118	belongs to the thioredoxin family
H9N25_RS03340	COG2133	pyrroloquinoline quinone binding
H9N25_RS03355	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H9N25_RS03355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9N25_RS03365	COG0028	Belongs to the TPP enzyme family
H9N25_RS03375	COG3185	4-Hydroxyphenylpyruvate dioxygenase
H9N25_RS03390	COG0179	Fumarylacetoacetate (FAA) hydrolase
H9N25_RS03415	COG4221	oxidoreductase activity
H9N25_RS03435	COG0791	NLP P60 protein
H9N25_RS03440	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS03460	COG0423	glycine-tRNA ligase activity
H9N25_RS03485	COG4585	Histidine kinase
H9N25_RS03490	COG2197	response regulator
H9N25_RS03495	COG0584	glycerophosphoryl diester phosphodiesterase
H9N25_RS03550	COG0586	Pfam SNARE associated Golgi protein
H9N25_RS03585	COG0443	Heat shock 70 kDa protein
H9N25_RS03590	COG4206	TonB-dependent receptor
H9N25_RS03590	COG1629	transport
H9N25_RS03615	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H9N25_RS03645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9N25_RS03665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H9N25_RS03700	COG0633	Ferredoxin
H9N25_RS03725	COG0424	maF-like protein
H9N25_RS03735	COG0248	Ppx GppA phosphatase
H9N25_RS03745	COG0484	heat shock protein binding
H9N25_RS03750	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H9N25_RS03755	COG2884	Cell division ATP-binding protein ftsE
H9N25_RS03775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9N25_RS03780	COG0563	adenylate kinase activity
H9N25_RS03790	COG0791	NLP P60 protein
H9N25_RS03800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H9N25_RS03800	COG0140	phosphoribosyl-ATP diphosphatase activity
H9N25_RS03805	COG0107	imidazoleglycerol-phosphate synthase activity
H9N25_RS03810	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H9N25_RS03815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H9N25_RS03820	COG0131	Imidazoleglycerol-phosphate dehydratase
H9N25_RS03820	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H9N25_RS03825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9N25_RS03835	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H9N25_RS03840	COG2989	Protein conserved in bacteria
H9N25_RS03850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9N25_RS03915	COG0463	Glycosyl transferase, family 2
H9N25_RS03935	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H9N25_RS03940	COG0750	zinc metalloprotease
H9N25_RS03950	COG2814	Major facilitator Superfamily
H9N25_RS03965	COG1846	Transcriptional regulator
H9N25_RS03970	COG5002	protein histidine kinase activity
H9N25_RS03975	COG0561	phosphatase activity
H9N25_RS03980	COG4206	TonB-dependent receptor
H9N25_RS03980	COG1629	transport
H9N25_RS03995	COG0738	Major facilitator superfamily
H9N25_RS04010	COG1063	alcohol dehydrogenase
H9N25_RS04015	COG1082	Xylose isomerase domain protein TIM barrel
H9N25_RS04025	COG1629	transport
H9N25_RS04030	COG0561	phosphatase activity
H9N25_RS04045	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
H9N25_RS04060	COG3250	beta-galactosidase activity
H9N25_RS04065	COG4948	Mandelate Racemase Muconate Lactonizing
H9N25_RS04070	COG3507	Belongs to the glycosyl hydrolase 43 family
H9N25_RS04080	COG2382	esterase
H9N25_RS04080	COG3693	PFAM glycoside hydrolase, family 10
H9N25_RS04080	COG3507	Belongs to the glycosyl hydrolase 43 family
H9N25_RS04100	COG0745	RESPONSE REGULATOR receiver
H9N25_RS04100	COG2205	protein histidine kinase activity
H9N25_RS04100	COG3292	Two component regulator propeller
H9N25_RS04105	COG1501	Belongs to the glycosyl hydrolase 31 family
H9N25_RS04110	COG1472	Belongs to the glycosyl hydrolase 3 family
H9N25_RS04125	COG1309	transcriptional regulator
H9N25_RS04135	COG0402	S-adenosylhomocysteine deaminase activity
H9N25_RS04140	COG0222	ribosome binding
H9N25_RS04170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS04175	COG2353	YceI-like domain
H9N25_RS04185	COG1629	transport
H9N25_RS04185	COG4206	TonB-dependent receptor
H9N25_RS04230	COG0714	Associated with various cellular activities
H9N25_RS04240	COG1522	sequence-specific DNA binding
H9N25_RS04245	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H9N25_RS04270	COG4529	Protein conserved in bacteria
H9N25_RS04280	COG0702	epimerase
H9N25_RS04295	COG4771	TonB-dependent receptor
H9N25_RS04330	COG3250	beta-galactosidase activity
H9N25_RS04335	COG3345	alpha-galactosidase
H9N25_RS04360	COG3486	L-lysine 6-monooxygenase (NADPH) activity
H9N25_RS04370	COG0076	glutamate decarboxylase activity
H9N25_RS04385	COG1959	2 iron, 2 sulfur cluster binding
H9N25_RS04390	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9N25_RS04395	COG1648	precorrin-2 dehydrogenase activity
H9N25_RS04395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H9N25_RS04400	COG0730	response to heat
H9N25_RS04405	COG0175	sulfate reduction
H9N25_RS04415	COG2895	sulfate adenylyltransferase (ATP) activity
H9N25_RS04440	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H9N25_RS04445	COG3387	PFAM Glycoside hydrolase 15-related
H9N25_RS04450	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H9N25_RS04455	COG4191	Histidine kinase
H9N25_RS04460	COG2204	response regulator
H9N25_RS04470	COG1136	(ABC) transporter
H9N25_RS04485	COG0577	efflux transmembrane transporter activity
H9N25_RS04495	COG1136	(ABC) transporter
H9N25_RS04495	COG0577	efflux transmembrane transporter activity
H9N25_RS04500	COG1136	(ABC) transporter
H9N25_RS04500	COG0577	efflux transmembrane transporter activity
H9N25_RS04520	COG4948	Mandelate Racemase Muconate Lactonizing
H9N25_RS04535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9N25_RS04555	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9N25_RS04570	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H9N25_RS04575	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H9N25_RS04580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9N25_RS04595	COG3655	Transcriptional regulator
H9N25_RS04600	COG0045	succinate-CoA ligase (ADP-forming) activity
H9N25_RS04640	COG1136	(ABC) transporter
H9N25_RS04670	COG0758	DNA mediated transformation
H9N25_RS04670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9N25_RS04680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H9N25_RS04705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9N25_RS04705	COG1796	DNA polymerase
H9N25_RS04715	COG0616	signal peptide processing
H9N25_RS04725	COG1183	phosphatidylcholine synthase activity
H9N25_RS04730	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H9N25_RS04735	COG0284	orotidine-5'-phosphate decarboxylase activity
H9N25_RS04770	COG1674	ftsk spoiiie
H9N25_RS04790	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H9N25_RS04790	COG0321	lipoyl(octanoyl) transferase activity
H9N25_RS04830	COG1595	DNA-templated transcription, initiation
H9N25_RS04845	COG0561	phosphatase activity
H9N25_RS04855	COG2207	Transcriptional regulator
H9N25_RS04855	COG4753	response regulator
H9N25_RS04885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9N25_RS04930	COG2207	Transcriptional regulator
H9N25_RS04935	COG2755	lipolytic protein G-D-S-L family
H9N25_RS04935	COG0657	acetylesterase activity
H9N25_RS04980	COG4977	sequence-specific DNA binding
H9N25_RS04980	COG1917	Cupin 2, conserved barrel domain protein
H9N25_RS04985	COG4221	oxidoreductase activity
H9N25_RS05005	COG2205	protein histidine kinase activity
H9N25_RS05015	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS05020	COG2721	sulfolactate sulfo-lyase activity
H9N25_RS05025	COG0738	Major facilitator superfamily
H9N25_RS05035	COG4977	sequence-specific DNA binding
H9N25_RS05075	COG0861	Integral membrane protein TerC family
H9N25_RS05105	COG3279	Response regulator of the LytR AlgR family
H9N25_RS05110	COG3275	phosphorelay sensor kinase activity
H9N25_RS05115	COG1131	(ABC) transporter
H9N25_RS05170	COG4771	TonB-dependent receptor
H9N25_RS05240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9N25_RS05265	COG1611	Belongs to the LOG family
H9N25_RS05270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9N25_RS05275	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H9N25_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS05290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9N25_RS05295	COG0135	phosphoribosylanthranilate isomerase activity
H9N25_RS05300	COG0133	tryptophan synthase activity
H9N25_RS05305	COG0159	tryptophan synthase activity
H9N25_RS05310	COG0702	epimerase
H9N25_RS05315	COG0705	Rhomboid family
H9N25_RS05330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9N25_RS05410	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9N25_RS05415	COG1733	regulation of RNA biosynthetic process
H9N25_RS05420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H9N25_RS05440	COG0009	L-threonylcarbamoyladenylate synthase
H9N25_RS05445	COG0069	glutamate synthase activity
H9N25_RS05455	COG0017	Asparaginyl-tRNA synthetase
H9N25_RS05470	COG2308	Evidence 4 Homologs of previously reported genes of
H9N25_RS05475	COG1528	Iron-storage protein
H9N25_RS05485	COG0456	acetyltransferase
H9N25_RS05490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9N25_RS05495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9N25_RS05515	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H9N25_RS05540	COG0346	lactoylglutathione lyase activity
H9N25_RS05545	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H9N25_RS05560	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H9N25_RS05565	COG0328	RNA-DNA hybrid ribonuclease activity
H9N25_RS05575	COG4977	sequence-specific DNA binding
H9N25_RS05575	COG1917	Cupin 2, conserved barrel domain protein
H9N25_RS05580	COG4771	TonB-dependent receptor
H9N25_RS05585	COG0702	epimerase
H9N25_RS05590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H9N25_RS05600	COG4948	Mandelate Racemase Muconate Lactonizing
H9N25_RS05605	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS05610	COG3386	PFAM SMP-30 Gluconolaconase
H9N25_RS05630	COG1629	transport
H9N25_RS05630	COG4206	TonB-dependent receptor
H9N25_RS05635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9N25_RS05650	COG0366	Alpha amylase catalytic
H9N25_RS05655	COG1609	Transcriptional regulator
H9N25_RS05680	COG1629	transport
H9N25_RS05720	COG4977	sequence-specific DNA binding
H9N25_RS05745	COG1522	sequence-specific DNA binding
H9N25_RS05760	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS05780	COG1629	transport
H9N25_RS05785	COG0702	epimerase
H9N25_RS05795	COG0488	(ABC) transporter
H9N25_RS05815	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
H9N25_RS05835	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H9N25_RS05850	COG1629	transport
H9N25_RS05875	COG1764	response to oxidative stress
H9N25_RS05880	COG0596	Alpha beta hydrolase
H9N25_RS05885	COG3275	phosphorelay sensor kinase activity
H9N25_RS05910	COG2855	membrane
H9N25_RS05940	COG3279	Response regulator of the LytR AlgR family
H9N25_RS05945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9N25_RS05960	COG4771	TonB-dependent receptor
H9N25_RS05970	COG1785	Belongs to the alkaline phosphatase family
H9N25_RS05985	COG0006	proline dipeptidase activity
H9N25_RS06010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9N25_RS06020	COG3938	Belongs to the proline racemase family
H9N25_RS06025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9N25_RS06040	COG0531	amino acid
H9N25_RS06055	COG3279	Response regulator of the LytR AlgR family
H9N25_RS06065	COG3292	Two component regulator propeller
H9N25_RS06065	COG2205	protein histidine kinase activity
H9N25_RS06065	COG0745	RESPONSE REGULATOR receiver
H9N25_RS06065	COG2205	protein histidine kinase activity
H9N25_RS06065	COG3292	Two component regulator propeller
H9N25_RS06065	COG0745	RESPONSE REGULATOR receiver
H9N25_RS06070	COG1629	transport
H9N25_RS06100	COG3279	Response regulator of the LytR AlgR family
H9N25_RS06105	COG3275	phosphorelay sensor kinase activity
H9N25_RS06180	COG0745	RESPONSE REGULATOR receiver
H9N25_RS06185	COG5002	protein histidine kinase activity
H9N25_RS06185	COG3850	Histidine kinase
H9N25_RS06195	COG0671	phosphoesterase, PA-phosphatase related
H9N25_RS06210	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9N25_RS06220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9N25_RS06230	COG0702	epimerase
H9N25_RS06250	COG0673	inositol 2-dehydrogenase activity
H9N25_RS06275	COG4221	oxidoreductase activity
H9N25_RS06335	COG0745	RESPONSE REGULATOR receiver
H9N25_RS06335	COG3292	Two component regulator propeller
H9N25_RS06335	COG2205	protein histidine kinase activity
H9N25_RS06335	COG0745	RESPONSE REGULATOR receiver
H9N25_RS06335	COG2205	protein histidine kinase activity
H9N25_RS06335	COG3292	Two component regulator propeller
H9N25_RS06370	COG4771	TonB-dependent receptor
H9N25_RS06375	COG0702	epimerase
H9N25_RS06380	COG1629	transport
H9N25_RS06405	COG1085	galactose-1-phosphate uridylyltransferase
H9N25_RS06410	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H9N25_RS06420	COG0025	NhaP-type Na H and K H
H9N25_RS06445	COG1360	Flagellar Motor Protein
H9N25_RS06465	COG5002	protein histidine kinase activity
H9N25_RS06470	COG0163	prenyltransferase activity
H9N25_RS06480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9N25_RS06490	COG0483	inositol monophosphate 1-phosphatase activity
H9N25_RS06495	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H9N25_RS06530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9N25_RS06550	COG0527	aspartate kinase activity
H9N25_RS06555	COG1247	-acetyltransferase
H9N25_RS06560	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H9N25_RS06570	COG1193	negative regulation of DNA recombination
H9N25_RS06575	COG2133	pyrroloquinoline quinone binding
H9N25_RS06580	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H9N25_RS06595	COG0572	uridine kinase
H9N25_RS06600	COG0791	NLP P60 protein
H9N25_RS06600	COG1388	LysM domain
H9N25_RS06605	COG0783	Belongs to the Dps family
H9N25_RS06610	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H9N25_RS06625	COG0442	prolyl-tRNA aminoacylation
H9N25_RS06650	COG2197	response regulator
H9N25_RS06680	COG2885	chlorophyll binding
H9N25_RS06690	COG0587	DNA-directed DNA polymerase activity
H9N25_RS06705	COG0463	Glycosyl transferase, family 2
H9N25_RS06710	COG3104	oligopeptide transport
H9N25_RS06715	COG3104	oligopeptide transport
H9N25_RS06725	COG0183	Belongs to the thiolase family
H9N25_RS06745	COG1480	7TM receptor with intracellular HD hydrolase
H9N25_RS06795	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
H9N25_RS06810	COG0673	inositol 2-dehydrogenase activity
H9N25_RS06825	COG3685	Protein conserved in bacteria
H9N25_RS06855	COG4106	trans-aconitate 2-methyltransferase activity
H9N25_RS06980	COG0697	spore germination
H9N25_RS06985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9N25_RS07030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9N25_RS07045	COG0346	lactoylglutathione lyase activity
H9N25_RS07100	COG0667	Aldo Keto reductase
H9N25_RS07110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9N25_RS07155	COG4953	penicillin-binding protein 1C
H9N25_RS07175	COG1754	DNA topoisomerase type I activity
H9N25_RS07175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9N25_RS07180	COG0386	Belongs to the glutathione peroxidase family
H9N25_RS07185	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9N25_RS07190	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H9N25_RS07205	COG1609	Transcriptional regulator
H9N25_RS07215	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS07220	COG1312	Catalyzes the dehydration of D-mannonate
H9N25_RS07250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9N25_RS07260	COG4771	TonB-dependent receptor
H9N25_RS07275	COG1629	transport
H9N25_RS07275	COG4206	TonB-dependent receptor
H9N25_RS07285	COG0700	Nucleoside recognition
H9N25_RS07295	COG0706	membrane insertase activity
H9N25_RS07300	COG0504	CTP synthase activity
H9N25_RS07325	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H9N25_RS07335	COG1428	Deoxynucleoside kinase
H9N25_RS07340	COG0180	Tryptophanyl-tRNA synthetase
H9N25_RS07350	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9N25_RS07355	COG1136	(ABC) transporter
H9N25_RS07380	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H9N25_RS07385	COG0577	efflux transmembrane transporter activity
H9N25_RS07385	COG1136	(ABC) transporter
H9N25_RS07390	COG0436	Aminotransferase
H9N25_RS07405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H9N25_RS07415	COG0640	Transcriptional regulator
H9N25_RS07425	COG1199	ATP-dependent helicase activity
H9N25_RS07425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9N25_RS07435	COG0745	RESPONSE REGULATOR receiver
H9N25_RS07440	COG3279	Response regulator of the LytR AlgR family
H9N25_RS07450	COG3279	Response regulator of the LytR AlgR family
H9N25_RS07470	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
H9N25_RS07500	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
H9N25_RS07540	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9N25_RS07550	COG3153	acetyltransferase
H9N25_RS07550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9N25_RS07555	COG2255	four-way junction helicase activity
H9N25_RS07560	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9N25_RS07570	COG1678	Uncharacterized ACR, COG1678
H9N25_RS07575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H9N25_RS07580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H9N25_RS07585	COG2081	HI0933 family
H9N25_RS07605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H9N25_RS07620	COG2270	Major facilitator Superfamily
H9N25_RS07645	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H9N25_RS07650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H9N25_RS07655	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H9N25_RS07660	COG3422	double-strand break repair
H9N25_RS07680	COG0612	Peptidase, M16
H9N25_RS07690	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9N25_RS07695	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H9N25_RS07705	COG1349	DNA-binding transcription factor activity
H9N25_RS07710	COG0745	RESPONSE REGULATOR receiver
H9N25_RS07725	COG0489	protein tyrosine kinase activity
H9N25_RS07735	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H9N25_RS07740	COG2244	polysaccharide biosynthetic process
H9N25_RS07755	COG0438	transferase activity, transferring glycosyl groups
H9N25_RS07770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H9N25_RS07775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H9N25_RS07785	COG0367	asparagine synthase
H9N25_RS07860	COG0604	alcohol dehydrogenase
H9N25_RS07910	COG1295	ribonuclease BN
H9N25_RS07930	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9N25_RS07945	COG3142	Participates in the control of copper homeostasis
H9N25_RS07955	COG1446	asparaginase
H9N25_RS07960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9N25_RS07965	COG0436	Aminotransferase
H9N25_RS07975	COG1477	protein flavinylation
H9N25_RS07985	COG2814	Major facilitator Superfamily
H9N25_RS07990	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H9N25_RS08005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H9N25_RS08035	COG0406	alpha-ribazole phosphatase activity
H9N25_RS08040	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
H9N25_RS08050	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H9N25_RS08055	COG0791	NLP P60 protein
H9N25_RS08060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS08120	COG4585	Histidine kinase
H9N25_RS08165	COG1304	FMN binding
H9N25_RS08175	COG3254	rhamnose metabolic process
H9N25_RS08180	COG0179	Fumarylacetoacetate (FAA) hydrolase
H9N25_RS08185	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS08225	COG2169	Transcriptional regulator
H9N25_RS08240	COG1629	transport
H9N25_RS08255	COG4771	TonB-dependent receptor
H9N25_RS08265	COG0702	epimerase
H9N25_RS08305	COG3250	beta-galactosidase activity
H9N25_RS08340	COG0673	inositol 2-dehydrogenase activity
H9N25_RS08355	COG1414	Transcriptional regulator
H9N25_RS08360	COG3408	Glycogen debranching enzyme
H9N25_RS08370	COG3250	beta-galactosidase activity
H9N25_RS08385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H9N25_RS08395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H9N25_RS08400	COG1607	acyl-coa hydrolase
H9N25_RS08405	COG0738	Major facilitator superfamily
H9N25_RS08410	COG3940	Belongs to the glycosyl hydrolase 43 family
H9N25_RS08435	COG2160	L-arabinose isomerase activity
H9N25_RS08465	COG1733	regulation of RNA biosynthetic process
H9N25_RS08565	COG4771	TonB-dependent receptor
H9N25_RS08570	COG0702	epimerase
H9N25_RS08590	COG3525	Glycosyl hydrolase, family 20, catalytic domain
H9N25_RS08610	COG3279	Response regulator of the LytR AlgR family
H9N25_RS08630	COG0577	efflux transmembrane transporter activity
H9N25_RS08635	COG1136	(ABC) transporter
H9N25_RS08690	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9N25_RS08700	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H9N25_RS08705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H9N25_RS08715	COG0070	glutamate synthase
H9N25_RS08715	COG0069	glutamate synthase activity
H9N25_RS08715	COG0067	glutamate synthase
H9N25_RS08760	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
H9N25_RS08780	COG0745	RESPONSE REGULATOR receiver
H9N25_RS08785	COG4251	negative regulation of phosphorylation
H9N25_RS08790	COG2197	response regulator
H9N25_RS08810	COG4206	TonB-dependent receptor
H9N25_RS08820	COG1609	Transcriptional regulator
H9N25_RS08840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H9N25_RS08870	COG2211	Major facilitator Superfamily
H9N25_RS08880	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H9N25_RS08885	COG2086	electron transfer activity
H9N25_RS08905	COG0305	Participates in initiation and elongation during chromosome replication
H9N25_RS08910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9N25_RS08920	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H9N25_RS08920	COG0517	IMP dehydrogenase activity
H9N25_RS08925	COG0514	ATP-dependent DNA helicase (RecQ)
H9N25_RS08930	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H9N25_RS08935	COG2080	2 iron, 2 sulfur cluster binding
H9N25_RS08940	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H9N25_RS08945	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H9N25_RS08965	COG1666	GTP binding
H9N25_RS08975	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H9N25_RS08990	COG0363	glucosamine-6-phosphate deaminase activity
H9N25_RS08995	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9N25_RS09000	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H9N25_RS09015	COG1629	transport
H9N25_RS09035	COG0584	glycerophosphoryl diester phosphodiesterase
H9N25_RS09045	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H9N25_RS09050	COG0156	8-amino-7-oxononanoate synthase activity
H9N25_RS09070	COG0823	Involved in the tonB-independent uptake of proteins
H9N25_RS09075	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H9N25_RS09080	COG2326	polyphosphate kinase activity
H9N25_RS09095	COG1999	signal sequence binding
H9N25_RS09115	COG1858	cytochrome C peroxidase
H9N25_RS09130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9N25_RS09135	COG0527	aspartate kinase activity
H9N25_RS09145	COG0019	diaminopimelate decarboxylase activity
H9N25_RS09150	COG1131	(ABC) transporter
H9N25_RS09215	COG1960	acyl-CoA dehydrogenase activity
H9N25_RS09225	COG0277	FAD linked oxidase domain protein
H9N25_RS09250	COG3275	phosphorelay sensor kinase activity
H9N25_RS09255	COG1136	(ABC) transporter
H9N25_RS09255	COG0577	efflux transmembrane transporter activity
H9N25_RS09260	COG1136	(ABC) transporter
H9N25_RS09275	COG1619	proteins homologs of microcin C7 resistance protein MccF
H9N25_RS09285	COG0513	Belongs to the DEAD box helicase family
H9N25_RS09290	COG2885	chlorophyll binding
H9N25_RS09300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9N25_RS09320	COG0813	purine-nucleoside phosphorylase activity
H9N25_RS09325	COG1739	Uncharacterized protein family UPF0029
H9N25_RS09330	COG0697	spore germination
H9N25_RS09335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9N25_RS09335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9N25_RS09340	COG2890	protein-(glutamine-N5) methyltransferase activity
H9N25_RS09350	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H9N25_RS09355	COG1216	Glycosyl transferase, family 2
H9N25_RS09370	COG0598	Magnesium transport protein CorA
H9N25_RS09375	COG2239	Acts as a magnesium transporter
H9N25_RS09385	COG1764	response to oxidative stress
H9N25_RS09390	COG1289	transmembrane transporter activity
H9N25_RS09395	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H9N25_RS09405	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H9N25_RS09425	COG0408	coproporphyrinogen oxidase activity
H9N25_RS09430	COG2814	Major facilitator Superfamily
H9N25_RS09475	COG0123	including yeast histone deacetylase and acetoin utilization protein
H9N25_RS09480	COG3781	membrane
H9N25_RS09485	COG3844	kynureninase activity
H9N25_RS09490	COG2094	Belongs to the DNA glycosylase MPG family
H9N25_RS09495	COG1956	GAF domain-containing protein
H9N25_RS09525	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H9N25_RS09540	COG4206	TonB-dependent receptor
H9N25_RS09560	COG0564	pseudouridine synthase activity
H9N25_RS09565	COG0745	RESPONSE REGULATOR receiver
H9N25_RS09570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS09575	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9N25_RS09650	COG1793	dna ligase
H9N25_RS09670	COG3118	belongs to the thioredoxin family
H9N25_RS09680	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9N25_RS09685	COG1058	Belongs to the CinA family
H9N25_RS09685	COG1546	Belongs to the CinA family
H9N25_RS09695	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9N25_RS09700	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9N25_RS09700	COG1388	LysM domain
H9N25_RS09710	COG1234	tRNA 3'-trailer cleavage
H9N25_RS09720	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H9N25_RS09725	COG1702	phosphate starvation-inducible protein PhoH
H9N25_RS09740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9N25_RS09745	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H9N25_RS09755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H9N25_RS09760	COG1185	polyribonucleotide nucleotidyltransferase activity
H9N25_RS09765	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H9N25_RS09775	COG0824	Thioesterase
H9N25_RS09790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H9N25_RS09800	COG0602	queuosine metabolic process
H9N25_RS09810	COG3132	Protein of unknown function, DUF480
H9N25_RS09815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9N25_RS09820	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
H9N25_RS09840	COG0300	oxidoreductase activity
H9N25_RS09850	COG0798	PFAM Bile acid sodium symporter
H9N25_RS09855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9N25_RS09875	COG3537	Alpha-1,2-mannosidase
H9N25_RS09880	COG0482	sulfurtransferase activity
H9N25_RS09890	COG0745	RESPONSE REGULATOR receiver
H9N25_RS09895	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H9N25_RS09905	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS09915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H9N25_RS09925	COG2146	nitrite reductase [NAD(P)H] activity
H9N25_RS09925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9N25_RS09935	COG2223	nitrite transmembrane transporter activity
H9N25_RS09940	COG0243	molybdopterin cofactor binding
H9N25_RS09950	COG1773	rubredoxin
H9N25_RS09955	COG0746	molybdenum cofactor guanylyltransferase activity
H9N25_RS09985	COG0280	phosphate acetyltransferase
H9N25_RS09985	COG0857	belongs to the CobB CobQ family
H9N25_RS09990	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H9N25_RS10005	COG1914	H( )-stimulated, divalent metal cation uptake system
H9N25_RS10020	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H9N25_RS10030	COG0025	NhaP-type Na H and K H
H9N25_RS10080	COG3239	Fatty acid desaturase
H9N25_RS10100	COG0647	UMP catabolic process
H9N25_RS10115	COG3525	Glycosyl hydrolase, family 20, catalytic domain
H9N25_RS10145	COG4771	TonB-dependent receptor
H9N25_RS10165	COG0745	RESPONSE REGULATOR receiver
H9N25_RS10165	COG2205	protein histidine kinase activity
H9N25_RS10165	COG3292	Two component regulator propeller
H9N25_RS10170	COG3292	Two component regulator propeller
H9N25_RS10170	COG2205	protein histidine kinase activity
H9N25_RS10170	COG0745	RESPONSE REGULATOR receiver
H9N25_RS10175	COG0745	RESPONSE REGULATOR receiver
H9N25_RS10175	COG3292	Two component regulator propeller
H9N25_RS10175	COG2205	protein histidine kinase activity
H9N25_RS10200	COG1629	transport
H9N25_RS10210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9N25_RS10215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS10225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS10245	COG4771	TonB-dependent receptor
H9N25_RS10265	COG1278	Cold shock
H9N25_RS10270	COG3279	Response regulator of the LytR AlgR family
H9N25_RS10295	COG3250	beta-galactosidase activity
H9N25_RS10300	COG3250	beta-galactosidase activity
H9N25_RS10315	COG0628	permease
H9N25_RS10425	COG4974	Belongs to the 'phage' integrase family
H9N25_RS10460	COG0587	DNA-directed DNA polymerase activity
H9N25_RS10500	COG1216	Glycosyl transferase, family 2
H9N25_RS10535	COG0562	UDP-galactopyranose mutase
H9N25_RS10585	COG2003	Belongs to the UPF0758 family
H9N25_RS10595	COG2197	response regulator
H9N25_RS10685	COG0671	phosphoesterase, PA-phosphatase related
H9N25_RS10690	COG0668	transmembrane transport
H9N25_RS10700	COG3279	Response regulator of the LytR AlgR family
H9N25_RS10715	COG0392	lysyltransferase activity
H9N25_RS10715	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H9N25_RS10755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9N25_RS10795	COG3507	Belongs to the glycosyl hydrolase 43 family
H9N25_RS10820	COG0384	phenazine biosynthesis protein PhzF
H9N25_RS10895	COG4771	TonB-dependent receptor
H9N25_RS10920	COG4106	trans-aconitate 2-methyltransferase activity
H9N25_RS10935	COG4771	TonB-dependent receptor
H9N25_RS10945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS10960	COG3291	Pkd domain containing protein
H9N25_RS10975	COG0561	phosphatase activity
H9N25_RS10980	COG4771	TonB-dependent receptor
H9N25_RS10990	COG2197	response regulator
H9N25_RS11000	COG0018	arginyl-trna synthetase
H9N25_RS11025	COG1166	arginine decarboxylase activity
H9N25_RS11070	COG0557	exoribonuclease II activity
H9N25_RS11085	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H9N25_RS11090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H9N25_RS11125	COG1595	DNA-templated transcription, initiation
H9N25_RS11150	COG3525	Glycosyl hydrolase, family 20, catalytic domain
H9N25_RS11155	COG0492	ferredoxin-NADP+ reductase activity
H9N25_RS11165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9N25_RS11200	COG0516	GMP reductase activity
H9N25_RS11200	COG0517	IMP dehydrogenase activity
H9N25_RS11220	COG3123	guanosine phosphorylase activity
H9N25_RS11230	COG0612	Peptidase, M16
H9N25_RS11245	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
H9N25_RS11260	COG3279	Response regulator of the LytR AlgR family
H9N25_RS11265	COG3275	phosphorelay sensor kinase activity
H9N25_RS11285	COG0697	spore germination
H9N25_RS11290	COG1522	sequence-specific DNA binding
H9N25_RS11300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9N25_RS11305	COG2264	protein methyltransferase activity
H9N25_RS11310	COG0149	triose-phosphate isomerase activity
H9N25_RS11325	COG0254	rRNA binding
H9N25_RS11345	COG0346	lactoylglutathione lyase activity
H9N25_RS11355	COG0822	iron-sulfur transferase activity
H9N25_RS11360	COG0316	Belongs to the HesB IscA family
H9N25_RS11380	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H9N25_RS11415	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H9N25_RS11450	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H9N25_RS11455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H9N25_RS11460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H9N25_RS11465	COG2363	Small membrane protein
H9N25_RS11480	COG1214	PFAM Peptidase M22, glycoprotease
H9N25_RS11495	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H9N25_RS11500	COG3279	Response regulator of the LytR AlgR family
H9N25_RS11505	COG3275	phosphorelay sensor kinase activity
H9N25_RS11525	COG1970	mechanosensitive ion channel activity
H9N25_RS11530	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H9N25_RS11550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H9N25_RS11555	COG1078	dGTPase activity
H9N25_RS11595	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H9N25_RS11605	COG1940	carbohydrate kinase activity
H9N25_RS11620	COG1917	Cupin 2, conserved barrel domain protein
H9N25_RS11620	COG2169	Transcriptional regulator
H9N25_RS11645	COG4206	TonB-dependent receptor
H9N25_RS11645	COG1629	transport
H9N25_RS11650	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H9N25_RS11660	COG3781	membrane
H9N25_RS11680	COG0443	Heat shock 70 kDa protein
H9N25_RS11685	COG2837	iron assimilation
H9N25_RS11740	COG1309	transcriptional regulator
H9N25_RS11750	COG1733	regulation of RNA biosynthetic process
H9N25_RS11755	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS11765	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS11925	COG3279	Response regulator of the LytR AlgR family
H9N25_RS11930	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H9N25_RS11935	COG0443	Heat shock 70 kDa protein
H9N25_RS11970	COG1011	Hydrolase
H9N25_RS11990	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H9N25_RS12005	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H9N25_RS12010	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H9N25_RS12015	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H9N25_RS12025	COG3279	Response regulator of the LytR AlgR family
H9N25_RS12030	COG2202	Pas domain
H9N25_RS12030	COG2205	protein histidine kinase activity
H9N25_RS12045	COG0436	Aminotransferase
H9N25_RS12060	COG0671	phosphoesterase, PA-phosphatase related
H9N25_RS12080	COG0673	inositol 2-dehydrogenase activity
H9N25_RS12105	COG1595	DNA-templated transcription, initiation
H9N25_RS12125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H9N25_RS12130	COG0303	'Molybdopterin
H9N25_RS12160	COG0315	cyclic pyranopterin monophosphate synthase activity
H9N25_RS12160	COG0521	Mo-molybdopterin cofactor biosynthetic process
H9N25_RS12175	COG1278	Cold shock
H9N25_RS12190	COG1132	(ABC) transporter
H9N25_RS12195	COG1132	(ABC) transporter
H9N25_RS12205	COG2996	Protein conserved in bacteria
H9N25_RS12260	COG1064	alcohol dehydrogenase
H9N25_RS12275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H9N25_RS12285	COG3408	Glycogen debranching enzyme
H9N25_RS12290	COG0542	response to heat
H9N25_RS12310	COG2223	nitrite transmembrane transporter activity
H9N25_RS12350	COG0726	polysaccharide deacetylase
H9N25_RS12355	COG0726	polysaccharide deacetylase
H9N25_RS12355	COG1649	PFAM Uncharacterised BCR, COG1649
H9N25_RS12375	COG0778	Nitroreductase
H9N25_RS12420	COG1331	Highly conserved protein containing a thioredoxin domain
H9N25_RS12425	COG4948	Mandelate Racemase Muconate Lactonizing
H9N25_RS12430	COG3757	hydrolase, family 25
H9N25_RS12435	COG2814	Major facilitator Superfamily
H9N25_RS12475	COG1733	regulation of RNA biosynthetic process
H9N25_RS12490	COG1196	nuclear chromosome segregation
H9N25_RS12495	COG2234	aminopeptidase activity
H9N25_RS12510	COG0357	Ribosomal RNA small subunit methyltransferase G
H9N25_RS12520	COG0343	queuine tRNA-ribosyltransferase activity
H9N25_RS12555	COG1741	Belongs to the pirin family
H9N25_RS12565	COG3525	Glycosyl hydrolase, family 20, catalytic domain
H9N25_RS12590	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H9N25_RS12600	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H9N25_RS12605	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H9N25_RS12610	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9N25_RS12615	COG1252	NADH dehydrogenase
H9N25_RS12640	COG0191	fructose-bisphosphate aldolase activity
H9N25_RS12645	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H9N25_RS12665	COG1271	oxidase subunit
H9N25_RS12680	COG1104	cysteine desulfurase activity
H9N25_RS12685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9N25_RS12690	COG2226	methyltransferase
H9N25_RS12715	COG0237	dephospho-CoA kinase activity
H9N25_RS12725	COG1862	Preprotein translocase
H9N25_RS12735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9N25_RS12745	COG1132	(ABC) transporter
H9N25_RS12760	COG0012	GTP binding
H9N25_RS12775	COG2239	Acts as a magnesium transporter
H9N25_RS12795	COG0745	RESPONSE REGULATOR receiver
H9N25_RS12810	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
H9N25_RS12850	COG3507	Belongs to the glycosyl hydrolase 43 family
H9N25_RS12875	COG0702	epimerase
H9N25_RS12880	COG4771	TonB-dependent receptor
H9N25_RS12895	COG0702	epimerase
H9N25_RS12900	COG1629	transport
H9N25_RS12905	COG4733	cellulase activity
H9N25_RS12905	COG4447	cellulose binding
H9N25_RS12955	COG3279	Response regulator of the LytR AlgR family
H9N25_RS12985	COG4206	TonB-dependent receptor
H9N25_RS12985	COG1629	transport
H9N25_RS12990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS13000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9N25_RS13025	COG3275	phosphorelay sensor kinase activity
H9N25_RS13100	COG0745	RESPONSE REGULATOR receiver
H9N25_RS13100	COG2205	protein histidine kinase activity
H9N25_RS13100	COG3292	Two component regulator propeller
H9N25_RS13110	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H9N25_RS13130	COG1285	pathogenesis
H9N25_RS13140	COG0745	RESPONSE REGULATOR receiver
H9N25_RS13145	COG0583	DNA-binding transcription factor activity
H9N25_RS13155	COG0793	Belongs to the peptidase S41A family
H9N25_RS13210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H9N25_RS13225	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H9N25_RS13240	COG0456	acetyltransferase
H9N25_RS13275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H9N25_RS13285	COG0702	epimerase
H9N25_RS13290	COG4771	TonB-dependent receptor
H9N25_RS13305	COG1522	sequence-specific DNA binding
H9N25_RS13310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9N25_RS13320	COG4232	protein-disulfide reductase activity
H9N25_RS13325	COG3250	beta-galactosidase activity
H9N25_RS13345	COG3254	rhamnose metabolic process
H9N25_RS13360	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H9N25_RS13370	COG2755	lipolytic protein G-D-S-L family
H9N25_RS13375	COG2755	lipolytic protein G-D-S-L family
H9N25_RS13380	COG3401	FG-GAP repeat protein
H9N25_RS13415	COG0604	alcohol dehydrogenase
H9N25_RS13415	COG3321	synthase
H9N25_RS13420	COG0318	PFAM AMP-dependent synthetase and ligase
H9N25_RS13420	COG3321	synthase
H9N25_RS13420	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS13420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H9N25_RS13420	COG0300	oxidoreductase activity
H9N25_RS13425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9N25_RS13430	COG0596	Alpha beta hydrolase
H9N25_RS13465	COG0596	Alpha beta hydrolase
H9N25_RS13475	COG2234	aminopeptidase activity
H9N25_RS13480	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
H9N25_RS13485	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9N25_RS13505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9N25_RS13520	COG4912	Dna alkylation repair
H9N25_RS13525	COG0167	dihydroorotate dehydrogenase activity
H9N25_RS13535	COG1959	2 iron, 2 sulfur cluster binding
H9N25_RS13550	COG0488	(ABC) transporter
H9N25_RS13560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9N25_RS13560	COG0515	serine threonine protein kinase
H9N25_RS13565	COG0673	inositol 2-dehydrogenase activity
H9N25_RS13570	COG1477	protein flavinylation
H9N25_RS13575	COG3622	Belongs to the hyi family
H9N25_RS13590	COG1607	acyl-coa hydrolase
H9N25_RS13705	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
H9N25_RS13735	COG0673	inositol 2-dehydrogenase activity
H9N25_RS13745	COG0673	inositol 2-dehydrogenase activity
H9N25_RS13750	COG0525	valine-tRNA ligase activity
H9N25_RS13765	COG2217	Heavy metal translocating P-type atpase
H9N25_RS13770	COG3590	peptidase
H9N25_RS13795	COG0667	Aldo Keto reductase
H9N25_RS13800	COG0628	permease
H9N25_RS13815	COG3956	TIGRFAM MazG family protein
H9N25_RS13820	COG3012	SEC-C Motif Domain Protein
H9N25_RS13825	COG0101	tRNA pseudouridine synthase activity
H9N25_RS13845	COG3876	Protein conserved in bacteria
H9N25_RS13855	COG5002	protein histidine kinase activity
H9N25_RS13865	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H9N25_RS13875	COG0564	pseudouridine synthase activity
H9N25_RS13885	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H9N25_RS13895	COG2388	GCN5-related N-acetyl-transferase
H9N25_RS13905	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS13925	COG3604	Transcriptional regulator
H9N25_RS13930	COG3548	integral membrane protein
H9N25_RS13945	COG0346	lactoylglutathione lyase activity
H9N25_RS13960	COG0783	Belongs to the Dps family
H9N25_RS13975	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H9N25_RS13985	COG1335	isochorismatase
H9N25_RS13990	COG3604	Transcriptional regulator
H9N25_RS14000	COG3604	Transcriptional regulator
H9N25_RS14005	COG3604	Transcriptional regulator
H9N25_RS14010	COG0025	NhaP-type Na H and K H
H9N25_RS14045	COG1960	acyl-CoA dehydrogenase activity
H9N25_RS14055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H9N25_RS14060	COG0386	Belongs to the glutathione peroxidase family
H9N25_RS14070	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9N25_RS14080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H9N25_RS14090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H9N25_RS14100	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9N25_RS14115	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H9N25_RS14130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H9N25_RS14145	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H9N25_RS14150	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H9N25_RS14175	COG2183	response to ionizing radiation
H9N25_RS14175	COG0539	negative regulation of cytoplasmic translation
H9N25_RS14180	COG3525	Glycosyl hydrolase, family 20, catalytic domain
H9N25_RS14200	COG2207	Transcriptional regulator
H9N25_RS14205	COG1012	belongs to the aldehyde dehydrogenase family
H9N25_RS14220	COG3011	Protein conserved in bacteria
H9N25_RS14225	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H9N25_RS14230	COG0540	Belongs to the ATCase OTCase family
H9N25_RS14275	COG4206	TonB-dependent receptor
H9N25_RS14275	COG1629	transport
H9N25_RS14290	COG1940	carbohydrate kinase activity
H9N25_RS14295	COG1629	transport
H9N25_RS14315	COG0811	peptide transport
H9N25_RS14320	COG0848	biopolymer transport protein
H9N25_RS14335	COG0285	dihydrofolate synthase activity
H9N25_RS14350	COG1703	isobutyryl-CoA mutase activity
H9N25_RS14350	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H9N25_RS14350	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H9N25_RS14355	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H9N25_RS14420	COG0497	DNA recombination
H9N25_RS14450	COG0542	response to heat
H9N25_RS14475	COG0702	epimerase
H9N25_RS14480	COG1629	transport
H9N25_RS14485	COG0488	(ABC) transporter
H9N25_RS14510	COG4807	Protein conserved in bacteria
H9N25_RS14515	COG0513	Belongs to the DEAD box helicase family
H9N25_RS14545	COG0004	ammonium transporteR
H9N25_RS14550	COG1242	4 iron, 4 sulfur cluster binding
H9N25_RS14560	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
H9N25_RS14565	COG0531	amino acid
H9N25_RS14575	COG2095	MarC family integral membrane protein
H9N25_RS14580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9N25_RS14590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9N25_RS14590	COG0519	Catalyzes the synthesis of GMP from XMP
H9N25_RS14615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H9N25_RS14620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H9N25_RS14625	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
H9N25_RS14640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H9N25_RS14650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H9N25_RS14665	COG1610	YqeY-like protein
H9N25_RS14670	COG4221	oxidoreductase activity
H9N25_RS14680	COG2226	methyltransferase
H9N25_RS14685	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H9N25_RS14690	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H9N25_RS14700	COG2814	Major facilitator Superfamily
H9N25_RS14705	COG0531	amino acid
H9N25_RS14725	COG3158	transport of potassium into the cell
H9N25_RS14735	COG0179	Fumarylacetoacetate (FAA) hydrolase
H9N25_RS14745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H9N25_RS14750	COG3959	Transketolase, thiamine diphosphate binding domain
H9N25_RS14755	COG3958	Transketolase
H9N25_RS14760	COG1595	DNA-templated transcription, initiation
H9N25_RS14775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9N25_RS14780	COG0745	RESPONSE REGULATOR receiver
H9N25_RS14785	COG5002	protein histidine kinase activity
H9N25_RS14795	COG0564	pseudouridine synthase activity
H9N25_RS14800	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H9N25_RS14805	COG0505	Belongs to the CarA family
H9N25_RS14830	COG1309	transcriptional regulator
H9N25_RS14840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H9N25_RS14845	COG0156	8-amino-7-oxononanoate synthase activity
H9N25_RS14855	COG1054	Belongs to the UPF0176 family
H9N25_RS14865	COG4771	TonB-dependent receptor
H9N25_RS14870	COG0702	epimerase
H9N25_RS14900	COG1472	Belongs to the glycosyl hydrolase 3 family
H9N25_RS14910	COG0217	transcriptional regulatory protein
H9N25_RS14915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9N25_RS14950	COG0673	inositol 2-dehydrogenase activity
H9N25_RS14960	COG4654	Cytochrome c, class I
H9N25_RS14965	COG0673	inositol 2-dehydrogenase activity
H9N25_RS14975	COG2211	Major facilitator Superfamily
H9N25_RS14995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9N25_RS15030	COG0148	phosphopyruvate hydratase activity
H9N25_RS15040	COG2860	membrane
H9N25_RS15050	COG3034	peptidoglycan biosynthetic process
H9N25_RS15055	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS15060	COG2827	Endonuclease containing a URI domain
H9N25_RS15085	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H9N25_RS15085	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9N25_RS15095	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H9N25_RS15095	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H9N25_RS15100	COG3119	arylsulfatase activity
H9N25_RS15105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9N25_RS15110	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H9N25_RS15125	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
H9N25_RS15130	COG1301	dicarboxylic acid transport
H9N25_RS15135	COG1446	asparaginase
H9N25_RS15140	COG1132	(ABC) transporter
H9N25_RS15190	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
H9N25_RS15200	COG1472	Belongs to the glycosyl hydrolase 3 family
H9N25_RS15215	COG4206	TonB-dependent receptor
H9N25_RS15215	COG1629	transport
H9N25_RS15220	COG1940	carbohydrate kinase activity
H9N25_RS15220	COG1846	Transcriptional regulator
H9N25_RS15225	COG0681	Belongs to the peptidase S26 family
H9N25_RS15230	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H9N25_RS15240	COG1475	DNA binding
H9N25_RS15245	COG1192	Involved in chromosome partitioning
H9N25_RS15255	COG5002	protein histidine kinase activity
H9N25_RS15265	COG1082	Xylose isomerase domain protein TIM barrel
H9N25_RS15290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9N25_RS15295	COG0563	adenylate kinase activity
H9N25_RS15330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H9N25_RS15335	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H9N25_RS15340	COG2267	carboxylic ester hydrolase activity
H9N25_RS15355	COG0129	dihydroxy-acid dehydratase activity
H9N25_RS15365	COG0028	Belongs to the TPP enzyme family
H9N25_RS15370	COG0440	acetolactate synthase activity
H9N25_RS15385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H9N25_RS15390	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H9N25_RS15395	COG2329	Antibiotic biosynthesis monooxygenase
H9N25_RS15400	COG0066	3-isopropylmalate dehydratase activity
H9N25_RS15405	COG1119	ATPase activity
H9N25_RS15410	COG0473	3-isopropylmalate dehydrogenase activity
H9N25_RS15415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9N25_RS15420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9N25_RS15425	COG1917	Cupin 2, conserved barrel domain protein
H9N25_RS15475	COG1981	membrane
H9N25_RS15480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H9N25_RS15490	COG0745	RESPONSE REGULATOR receiver
H9N25_RS15495	COG5002	protein histidine kinase activity
H9N25_RS15505	COG0113	porphobilinogen synthase activity
H9N25_RS15510	COG0181	hydroxymethylbilane synthase activity
H9N25_RS15515	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H9N25_RS15520	COG0596	Alpha beta hydrolase
H9N25_RS15530	COG0668	transmembrane transport
H9N25_RS15555	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS15560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H9N25_RS15565	COG1127	ABC transporter
H9N25_RS15580	COG0116	Belongs to the methyltransferase superfamily
H9N25_RS15580	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9N25_RS15630	COG1295	ribonuclease BN
H9N25_RS15640	COG0531	amino acid
H9N25_RS15655	COG0702	epimerase
H9N25_RS15660	COG1629	transport
H9N25_RS15665	COG0513	Belongs to the DEAD box helicase family
H9N25_RS15670	COG0495	leucyl-tRNA aminoacylation
H9N25_RS15680	COG2177	Part of the ABC transporter FtsEX involved in
H9N25_RS15690	COG1968	undecaprenyl-diphosphatase activity
H9N25_RS15695	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H9N25_RS15700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9N25_RS15705	COG0196	riboflavin kinase activity
H9N25_RS15710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H9N25_RS15710	COG4651	solute:proton antiporter activity
H9N25_RS15720	COG4804	nuclease activity
H9N25_RS15725	COG0432	Pfam Uncharacterised protein family UPF0047
H9N25_RS15750	COG2169	Transcriptional regulator
H9N25_RS15760	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
H9N25_RS15810	COG1629	transport
H9N25_RS15825	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9N25_RS15840	COG0612	Peptidase, M16
H9N25_RS15860	COG0270	DNA (cytosine-5-)-methyltransferase activity
H9N25_RS15870	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
H9N25_RS15875	COG3237	CsbD-like
H9N25_RS15880	COG4771	TonB-dependent receptor
H9N25_RS15885	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H9N25_RS15895	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H9N25_RS15900	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9N25_RS15910	COG0552	protein localization to endoplasmic reticulum
H9N25_RS15920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9N25_RS15935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H9N25_RS15950	COG0726	polysaccharide deacetylase
H9N25_RS15970	COG2723	6-phospho-beta-galactosidase activity
H9N25_RS16000	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H9N25_RS16010	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H9N25_RS16025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9N25_RS16045	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H9N25_RS16050	COG1663	tetraacyldisaccharide 4'-kinase activity
H9N25_RS16080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9N25_RS16135	COG2972	Histidine kinase
H9N25_RS16140	COG3279	Response regulator of the LytR AlgR family
H9N25_RS16155	COG3119	arylsulfatase activity
H9N25_RS16165	COG0288	reversible hydration of carbon dioxide
H9N25_RS16170	COG0659	secondary active sulfate transmembrane transporter activity
H9N25_RS16180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9N25_RS16185	COG2814	Major facilitator Superfamily
H9N25_RS16195	COG1363	Peptidase, m42
H9N25_RS16205	COG0588	phosphoglycerate mutase activity
H9N25_RS16215	COG0708	Exodeoxyribonuclease III
H9N25_RS16220	COG0745	RESPONSE REGULATOR receiver
H9N25_RS16225	COG1595	DNA-templated transcription, initiation
H9N25_RS16235	COG5002	protein histidine kinase activity
H9N25_RS16250	COG1506	peptidase
H9N25_RS16265	COG0433	COG0433 Predicted ATPase
H9N25_RS16290	COG0443	Heat shock 70 kDa protein
H9N25_RS16320	COG0203	ribosomal protein L17
H9N25_RS16325	COG0202	RNA polymerase activity
H9N25_RS16330	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H9N25_RS16335	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9N25_RS16340	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H9N25_RS16345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H9N25_RS16350	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H9N25_RS16365	COG0200	Binds to the 23S rRNA
H9N25_RS16370	COG1841	ribosomal large subunit assembly
H9N25_RS16375	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H9N25_RS16380	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H9N25_RS16385	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H9N25_RS16390	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H9N25_RS16395	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H9N25_RS16400	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H9N25_RS16405	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H9N25_RS16410	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H9N25_RS16415	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H9N25_RS16420	COG0255	Belongs to the universal ribosomal protein uL29 family
H9N25_RS16425	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H9N25_RS16430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H9N25_RS16435	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H9N25_RS16440	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H9N25_RS16445	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H9N25_RS16450	COG0089	rRNA binding
H9N25_RS16455	COG0088	Forms part of the polypeptide exit tunnel
H9N25_RS16460	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H9N25_RS16470	COG0730	response to heat
H9N25_RS16510	COG0051	transcription antitermination factor activity, RNA binding
H9N25_RS16515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9N25_RS16520	COG0049	tRNA binding
H9N25_RS16525	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H9N25_RS16550	COG0702	epimerase
H9N25_RS16555	COG4771	TonB-dependent receptor
H9N25_RS16560	COG4771	TonB-dependent receptor
H9N25_RS16580	COG4628	conserved protein (DUF2132)
H9N25_RS16585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9N25_RS16605	COG1393	Belongs to the ArsC family
H9N25_RS16610	COG3275	phosphorelay sensor kinase activity
H9N25_RS16615	COG3279	Response regulator of the LytR AlgR family
H9N25_RS16620	COG1629	transport
H9N25_RS16620	COG4206	TonB-dependent receptor
H9N25_RS16635	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H9N25_RS16645	COG0579	oxidoreductase
H9N25_RS16660	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9N25_RS16675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9N25_RS16680	COG1574	metal-dependent hydrolase with the TIM-barrel fold
H9N25_RS16685	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H9N25_RS16705	COG0778	Nitroreductase
H9N25_RS16715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9N25_RS16735	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
H9N25_RS16740	COG5520	Belongs to the glycosyl hydrolase 30 family
H9N25_RS16745	COG0702	epimerase
H9N25_RS16750	COG4771	TonB-dependent receptor
H9N25_RS16800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H9N25_RS16865	COG0531	amino acid
H9N25_RS16890	COG0346	lactoylglutathione lyase activity
H9N25_RS16905	COG1381	Involved in DNA repair and RecF pathway recombination
H9N25_RS16930	COG0300	oxidoreductase activity
H9N25_RS16935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9N25_RS16955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H9N25_RS16960	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H9N25_RS16965	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H9N25_RS16980	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9N25_RS16985	COG0567	Dehydrogenase, E1 component
H9N25_RS16990	COG0415	Belongs to the DNA photolyase family
H9N25_RS16995	COG1090	epimerase
H9N25_RS17000	COG0415	Belongs to the DNA photolyase family
H9N25_RS17005	COG0545	Peptidyl-prolyl cis-trans isomerase
H9N25_RS17015	COG0545	Peptidyl-prolyl cis-trans isomerase
H9N25_RS17020	COG1960	acyl-CoA dehydrogenase activity
H9N25_RS17030	COG0183	Belongs to the thiolase family
H9N25_RS17035	COG1024	Enoyl-CoA hydratase
H9N25_RS17035	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9N25_RS17050	COG2885	chlorophyll binding
H9N25_RS17065	COG0405	Gamma-glutamyltransferase
H9N25_RS17090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9N25_RS17100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9N25_RS17115	COG0745	RESPONSE REGULATOR receiver
H9N25_RS17135	COG5433	transposase activity
H9N25_RS17155	COG0326	Molecular chaperone. Has ATPase activity
H9N25_RS17170	COG3279	Response regulator of the LytR AlgR family
H9N25_RS17175	COG2972	Histidine kinase
H9N25_RS17210	COG1360	Flagellar Motor Protein
H9N25_RS17255	COG1595	DNA-templated transcription, initiation
H9N25_RS17260	COG2322	membrane
H9N25_RS17275	COG1845	cytochrome c oxidase, subunit III
H9N25_RS17280	COG1845	cytochrome c oxidase, subunit III
H9N25_RS17285	COG0109	protoheme IX farnesyltransferase activity
H9N25_RS17295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H9N25_RS17300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H9N25_RS17325	COG0437	4 iron, 4 sulfur cluster binding
H9N25_RS17355	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9N25_RS17360	COG3682	Transcriptional regulator
H9N25_RS17465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9N25_RS17470	COG1215	transferase activity, transferring glycosyl groups
H9N25_RS17480	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H9N25_RS17505	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H9N25_RS17510	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H9N25_RS17515	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9N25_RS17520	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H9N25_RS17530	COG0356	it plays a direct role in the translocation of protons across the membrane
H9N25_RS17555	COG0322	excinuclease ABC activity
H9N25_RS17595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9N25_RS17605	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H9N25_RS17625	COG0110	maltose O-acetyltransferase activity
H9N25_RS17640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9N25_RS17655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H9N25_RS17665	COG0745	RESPONSE REGULATOR receiver
H9N25_RS17695	COG1694	Mazg nucleotide pyrophosphohydrolase
H9N25_RS17725	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H9N25_RS17735	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H9N25_RS17740	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H9N25_RS17760	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H9N25_RS17765	COG0416	fatty acid biosynthetic process
H9N25_RS17770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9N25_RS17775	COG0511	ligase activity, forming carbon-carbon bonds
H9N25_RS17785	COG0805	protein transport
H9N25_RS17790	COG0698	ribose 5-phosphate isomerase
H9N25_RS17800	COG1139	Iron-sulfur cluster binding protein
H9N25_RS17805	COG0022	dehydrogenase e1 component
H9N25_RS17830	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H9N25_RS17835	COG1621	beta-fructofuranosidase activity
H9N25_RS17845	COG0330	HflC and HflK could
H9N25_RS17850	COG1690	Belongs to the RtcB family
H9N25_RS17860	COG0165	Argininosuccinate lyase
H9N25_RS17865	COG4946	Tricorn protease homolog
H9N25_RS17865	COG0823	Involved in the tonB-independent uptake of proteins
H9N25_RS17865	COG1506	peptidase
H9N25_RS17885	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H9N25_RS17890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9N25_RS17900	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H9N25_RS17905	COG0137	argininosuccinate synthase activity
H9N25_RS17940	COG4771	TonB-dependent receptor
H9N25_RS17980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9N25_RS17990	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H9N25_RS18015	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H9N25_RS18035	COG0702	epimerase
H9N25_RS18050	COG3848	Pyruvate phosphate dikinase
H9N25_RS18050	COG0574	Belongs to the PEP-utilizing enzyme family
H9N25_RS18055	COG0300	oxidoreductase activity
H9N25_RS18075	COG0469	pyruvate kinase activity
H9N25_RS18085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9N25_RS18090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9N25_RS18095	COG0571	ribonuclease III activity
H9N25_RS18120	COG1561	YicC-like family, N-terminal region
H9N25_RS18125	COG0194	GDP metabolic process
H9N25_RS18145	COG1472	Belongs to the glycosyl hydrolase 3 family
H9N25_RS18160	COG0084	hydrolase, TatD family'
H9N25_RS18165	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H9N25_RS18170	COG1074	ATP-dependent DNA helicase activity
H9N25_RS18180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9N25_RS18190	COG0022	dehydrogenase e1 component
H9N25_RS18190	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9N25_RS18210	COG2183	response to ionizing radiation
H9N25_RS18230	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H9N25_RS18235	COG0052	Belongs to the universal ribosomal protein uS2 family
H9N25_RS18240	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H9N25_RS18250	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H9N25_RS18270	COG0528	UMP kinase activity
H9N25_RS18275	COG0233	cytoplasmic translational termination
H9N25_RS18280	COG1609	Transcriptional regulator
H9N25_RS18290	COG1522	sequence-specific DNA binding
H9N25_RS18320	COG0509	glycine decarboxylation via glycine cleavage system
H9N25_RS18335	COG0632	four-way junction helicase activity
H9N25_RS18340	COG0280	phosphate acetyltransferase
H9N25_RS18340	COG0281	malic enzyme
H9N25_RS18345	COG4932	domain protein
H9N25_RS18345	COG1388	LysM domain
H9N25_RS18350	COG0154	amidase activity
H9N25_RS18355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H9N25_RS18360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H9N25_RS18380	COG0756	dUTP diphosphatase activity
H9N25_RS18400	COG4753	response regulator
H9N25_RS18400	COG2207	Transcriptional regulator
H9N25_RS18405	COG0667	Aldo Keto reductase
H9N25_RS18440	COG2204	response regulator
H9N25_RS18445	COG2198	Histidine kinase
H9N25_RS18445	COG2205	protein histidine kinase activity
H9N25_RS18445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9N25_RS18445	COG0784	Response regulator, receiver
H9N25_RS18450	COG2378	regulation of single-species biofilm formation
H9N25_RS18460	COG0431	NADPH-dependent FMN reductase
H9N25_RS18465	COG1187	pseudouridine synthase activity
H9N25_RS18470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H9N25_RS18510	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9N25_RS18515	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9N25_RS18520	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H9N25_RS18525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H9N25_RS18540	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
H9N25_RS18540	COG0662	Cupin 2, conserved barrel domain protein
H9N25_RS18560	COG2244	polysaccharide biosynthetic process
H9N25_RS18585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9N25_RS18590	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H9N25_RS18595	COG0489	protein tyrosine kinase activity
H9N25_RS18605	COG4464	protein tyrosine phosphatase activity
H9N25_RS18610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H9N25_RS18655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9N25_RS18675	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H9N25_RS18715	COG1090	epimerase
H9N25_RS18730	COG4895	conserved protein (DUF2196)
H9N25_RS18740	COG0556	nucleotide-excision repair
H9N25_RS18775	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H9N25_RS18785	COG1011	Hydrolase
H9N25_RS18840	COG1446	asparaginase
H9N25_RS18870	COG3590	peptidase
H9N25_RS18890	COG0791	NLP P60 protein
H9N25_RS18895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H9N25_RS18900	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9N25_RS18910	COG4297	protein containing double-stranded beta helix domain
H9N25_RS18915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9N25_RS18920	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H9N25_RS18925	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H9N25_RS18960	COG0519	Catalyzes the synthesis of GMP from XMP
H9N25_RS18990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9N25_RS18995	COG0583	DNA-binding transcription factor activity
H9N25_RS19020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9N25_RS19025	COG1070	Carbohydrate kinase
H9N25_RS19045	COG4591	ABC-type transport system involved in lipoprotein release permease component
H9N25_RS19050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9N25_RS19060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H9N25_RS19065	COG1809	phosphosulfolactate synthase activity
H9N25_RS19120	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H9N25_RS19125	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9N25_RS19130	COG1609	Transcriptional regulator
H9N25_RS19135	COG1629	transport
H9N25_RS19140	COG0702	epimerase
H9N25_RS19155	COG2755	lipolytic protein G-D-S-L family
H9N25_RS19160	COG1012	belongs to the aldehyde dehydrogenase family
H9N25_RS19180	COG1904	glucuronate isomerase
H9N25_RS19185	COG2721	sulfolactate sulfo-lyase activity
H9N25_RS19190	COG0246	Mannitol dehydrogenase
H9N25_RS19220	COG2755	lipolytic protein G-D-S-L family
H9N25_RS19235	COG3781	membrane
H9N25_RS19265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H9N25_RS19290	COG2204	response regulator
H9N25_RS19295	COG1024	Enoyl-CoA hydratase
H9N25_RS19300	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H9N25_RS19300	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H9N25_RS19305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9N25_RS19340	COG0352	thiamine-phosphate diphosphorylase activity
H9N25_RS19360	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H9N25_RS19365	COG1595	DNA-templated transcription, initiation
H9N25_RS19390	COG1054	Belongs to the UPF0176 family
H9N25_RS19400	COG4948	Mandelate Racemase Muconate Lactonizing
H9N25_RS19430	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9N25_RS19455	COG0488	(ABC) transporter
H9N25_RS19460	COG2104	thiamine diphosphate biosynthetic process
H9N25_RS19465	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H9N25_RS19470	COG0352	thiamine-phosphate diphosphorylase activity
H9N25_RS19475	COG0352	thiamine-phosphate diphosphorylase activity
H9N25_RS19480	COG2022	thiamine diphosphate biosynthetic process
H9N25_RS19485	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H9N25_RS19490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H9N25_RS19495	COG4884	unkown
H9N25_RS19495	COG3831	ATPase activity
H9N25_RS19575	COG1525	nuclease
H9N25_RS19585	COG3279	Response regulator of the LytR AlgR family
H9N25_RS19590	COG3275	phosphorelay sensor kinase activity
H9N25_RS19650	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS19700	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9N25_RS19700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9N25_RS19705	COG1619	proteins homologs of microcin C7 resistance protein MccF
H9N25_RS19720	COG4771	TonB-dependent receptor
H9N25_RS19730	COG4771	TonB-dependent receptor
H9N25_RS19735	COG4771	TonB-dependent receptor
H9N25_RS19775	COG4771	TonB-dependent receptor
H9N25_RS19800	COG1629	transport
H9N25_RS19805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9N25_RS19820	COG1774	PSP1 C-terminal conserved region
H9N25_RS19825	COG0470	DNA polymerase III
H9N25_RS19840	COG1388	LysM domain
H9N25_RS19840	COG3942	CHAP domain
H9N25_RS19845	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9N25_RS19880	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9N25_RS19885	COG0606	chelatase, subunit chli
H9N25_RS19920	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H9N25_RS19925	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H9N25_RS19940	COG0612	Peptidase, M16
H9N25_RS19945	COG0242	peptide deformylase activity
H9N25_RS19960	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H9N25_RS19965	COG0489	protein tyrosine kinase activity
H9N25_RS19970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9N25_RS19980	COG0688	phosphatidylethanolamine metabolic process
H9N25_RS19985	COG0668	transmembrane transport
H9N25_RS19990	COG0335	large ribosomal subunit rRNA binding
H9N25_RS19995	COG0336	Belongs to the RNA methyltransferase TrmD family
H9N25_RS20005	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H9N25_RS20010	COG0228	four-way junction DNA binding
H9N25_RS20015	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
H9N25_RS20025	COG0393	Putative heavy-metal-binding
H9N25_RS20030	COG0205	6-phosphofructokinase activity
H9N25_RS20035	COG4232	protein-disulfide reductase activity
H9N25_RS20045	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
H9N25_RS20045	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
H9N25_RS20050	COG0799	negative regulation of ribosome biogenesis
H9N25_RS20055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9N25_RS20060	COG1556	Lactate utilization protein
H9N25_RS20080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9N25_RS20095	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H9N25_RS20110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H9N25_RS20115	COG3530	Putative quorum-sensing-regulated virulence factor
H9N25_RS20120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H9N25_RS20130	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H9N25_RS20135	COG1607	acyl-coa hydrolase
H9N25_RS20140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H9N25_RS20160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9N25_RS20175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9N25_RS20175	COG2022	thiamine diphosphate biosynthetic process
H9N25_RS20180	COG0788	formyltetrahydrofolate deformylase activity
H9N25_RS20200	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H9N25_RS20205	COG1301	dicarboxylic acid transport
H9N25_RS20210	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H9N25_RS20215	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H9N25_RS20220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H9N25_RS20230	COG0445	tRNA wobble uridine modification
H9N25_RS20235	COG0488	(ABC) transporter
H9N25_RS20240	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H9N25_RS20255	COG3511	phospholipase C
H9N25_RS20265	COG2197	response regulator
H9N25_RS20275	COG2207	Transcriptional regulator
H9N25_RS20280	COG4771	TonB-dependent receptor
H9N25_RS20305	COG5297	Belongs to the glycosyl hydrolase family 6
H9N25_RS20305	COG3250	beta-galactosidase activity
H9N25_RS20310	COG1309	transcriptional regulator
H9N25_RS20325	COG2814	Major facilitator Superfamily
H9N25_RS20330	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
H9N25_RS20345	COG0450	alkyl hydroperoxide reductase
H9N25_RS20355	COG0492	ferredoxin-NADP+ reductase activity
H9N25_RS20380	COG3384	dioxygenase
H9N25_RS20385	COG2353	YceI-like domain
H9N25_RS20420	COG0708	Exodeoxyribonuclease III
H9N25_RS20425	COG1228	amidohydrolase
H9N25_RS20430	COG0010	Belongs to the arginase family
H9N25_RS20440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9N25_RS20450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H9N25_RS20455	COG1131	(ABC) transporter
H9N25_RS20465	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9N25_RS20470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9N25_RS20470	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
H9N25_RS20475	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9N25_RS20480	COG1078	dGTPase activity
H9N25_RS20490	COG0802	atpase or kinase
H9N25_RS20495	COG0686	Belongs to the AlaDH PNT family
H9N25_RS20500	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
H9N25_RS20510	COG0156	8-amino-7-oxononanoate synthase activity
H9N25_RS20525	COG3409	Peptidoglycan-binding domain 1 protein
H9N25_RS20525	COG0793	Belongs to the peptidase S41A family
H9N25_RS20560	COG1595	DNA-templated transcription, initiation
H9N25_RS20565	COG2076	Multidrug Resistance protein
H9N25_RS20585	COG2050	protein possibly involved in aromatic compounds catabolism
H9N25_RS20600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9N25_RS20610	COG5002	protein histidine kinase activity
H9N25_RS20615	COG0784	Response regulator, receiver
H9N25_RS20615	COG5002	protein histidine kinase activity
H9N25_RS20625	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H9N25_RS20635	COG0745	RESPONSE REGULATOR receiver
H9N25_RS20645	COG1704	LemA family
H9N25_RS20660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9N25_RS20665	COG2204	response regulator
H9N25_RS20685	COG5002	protein histidine kinase activity
H9N25_RS20695	COG0306	phosphate transporter
H9N25_RS20720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H9N25_RS20755	COG0513	Belongs to the DEAD box helicase family
H9N25_RS20770	COG1760	l-serine dehydratase
H9N25_RS20780	COG1285	pathogenesis
H9N25_RS20795	COG0459	protein refolding
H9N25_RS20800	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H9N25_RS20825	COG1418	mRNA catabolic process
H9N25_RS20840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9N25_RS20840	COG0116	Belongs to the methyltransferase superfamily
H9N25_RS20860	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
H9N25_RS20875	COG0302	gtp cyclohydrolase
H9N25_RS20880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H9N25_RS20885	COG5000	phosphorelay sensor kinase activity
H9N25_RS20895	COG1649	PFAM Uncharacterised BCR, COG1649
H9N25_RS20910	COG0363	glucosamine-6-phosphate deaminase activity
H9N25_RS20915	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H9N25_RS20930	COG1349	DNA-binding transcription factor activity
H9N25_RS20950	COG1629	transport
H9N25_RS20965	COG1629	transport
H9N25_RS20995	COG0793	Belongs to the peptidase S41A family
H9N25_RS21005	COG3537	Alpha-1,2-mannosidase
H9N25_RS21010	COG3250	beta-galactosidase activity
H9N25_RS21030	COG1505	serine-type exopeptidase activity
H9N25_RS21040	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H9N25_RS21145	COG0542	response to heat
H9N25_RS21250	COG3209	COG3209 Rhs family protein
H9N25_RS21265	COG2986	histidine ammonia-lyase
H9N25_RS21270	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H9N25_RS21275	COG0583	DNA-binding transcription factor activity
H9N25_RS21280	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9N25_RS21315	COG2032	superoxide dismutase activity
H9N25_RS21335	COG1132	(ABC) transporter
H9N25_RS21340	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H9N25_RS21345	COG1597	lipid kinase activity
H9N25_RS21365	COG0124	histidyl-tRNA synthetase
H9N25_RS21375	COG0477	Major facilitator Superfamily
H9N25_RS21385	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9N25_RS21395	COG4152	abc transporter atp-binding protein
H9N25_RS21410	COG0673	inositol 2-dehydrogenase activity
H9N25_RS21415	COG3228	Belongs to the MtfA family
H9N25_RS21435	COG1725	Transcriptional regulator
H9N25_RS21445	COG1131	(ABC) transporter
H9N25_RS21460	COG1902	pentaerythritol trinitrate reductase activity
H9N25_RS21465	COG4771	TonB-dependent receptor
H9N25_RS21470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS21545	COG0321	lipoyl(octanoyl) transferase activity
H9N25_RS21565	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9N25_RS21565	COG1024	Enoyl-CoA hydratase
H9N25_RS21570	COG1028	Short-chain dehydrogenase reductase Sdr
H9N25_RS21575	COG0151	Belongs to the GarS family
H9N25_RS21585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS21595	COG0010	Belongs to the arginase family
H9N25_RS21600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9N25_RS21610	COG0038	chloride channel
H9N25_RS21615	COG3483	tryptophan 2,3-dioxygenase activity
H9N25_RS21630	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H9N25_RS21635	COG1530	ribonuclease E activity
H9N25_RS21645	COG0776	regulation of translation
H9N25_RS21665	COG0297	glycogen (starch) synthase activity
H9N25_RS21670	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H9N25_RS21675	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H9N25_RS21685	COG1960	acyl-CoA dehydrogenase activity
H9N25_RS21700	COG0779	Required for maturation of 30S ribosomal subunits
H9N25_RS21705	COG0195	Participates in both transcription termination and antitermination
H9N25_RS21710	COG5180	pathogenesis
H9N25_RS21710	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H9N25_RS21730	COG1216	Glycosyl transferase, family 2
H9N25_RS21735	COG0438	transferase activity, transferring glycosyl groups
H9N25_RS21755	COG1132	(ABC) transporter
H9N25_RS21785	COG0251	oxidation-reduction process
H9N25_RS21795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H9N25_RS21800	COG4771	TonB-dependent receptor
H9N25_RS21820	COG1132	(ABC) transporter
H9N25_RS21840	COG1228	amidohydrolase
H9N25_RS21855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H9N25_RS21860	COG0512	Glutamine amidotransferase of anthranilate synthase
H9N25_RS21865	COG0134	indole-3-glycerol-phosphate synthase activity
H9N25_RS21870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9N25_RS21875	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H9N25_RS21880	COG1272	protein, Hemolysin III
H9N25_RS21900	COG1597	lipid kinase activity
H9N25_RS21930	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H9N25_RS21950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9N25_RS21955	COG1538	Outer membrane efflux protein
H9N25_RS21970	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H9N25_RS21975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9N25_RS21990	COG1278	Cold shock
H9N25_RS22005	COG1053	succinate dehydrogenase
H9N25_RS22020	COG1629	transport
H9N25_RS22025	COG4771	TonB-dependent receptor
H9N25_RS22040	COG4585	Histidine kinase
H9N25_RS22050	COG2197	response regulator
H9N25_RS22080	COG3279	Response regulator of the LytR AlgR family
H9N25_RS22090	COG0494	nUDIX hydrolase
H9N25_RS22105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9N25_RS22125	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9N25_RS22155	COG1741	Belongs to the pirin family
H9N25_RS22160	COG1902	pentaerythritol trinitrate reductase activity
H9N25_RS22165	COG0640	Transcriptional regulator
H9N25_RS22175	COG1733	regulation of RNA biosynthetic process
H9N25_RS22200	COG2267	carboxylic ester hydrolase activity
H9N25_RS22205	COG1940	carbohydrate kinase activity
H9N25_RS22210	COG0673	inositol 2-dehydrogenase activity
H9N25_RS22220	COG0673	inositol 2-dehydrogenase activity
H9N25_RS22225	COG0673	inositol 2-dehydrogenase activity
H9N25_RS22235	COG1733	regulation of RNA biosynthetic process
H9N25_RS22240	COG1162	GTPase activity
H9N25_RS22255	COG0604	alcohol dehydrogenase
H9N25_RS22305	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H9N25_RS22310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS22315	COG1160	GTP binding
H9N25_RS22330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9N25_RS22340	COG0076	glutamate decarboxylase activity
H9N25_RS22345	COG0793	Belongs to the peptidase S41A family
H9N25_RS22350	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H9N25_RS22360	COG0670	Belongs to the BI1 family
H9N25_RS22370	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H9N25_RS22395	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H9N25_RS22400	COG0083	homoserine kinase activity
H9N25_RS22410	COG0527	aspartate kinase activity
H9N25_RS22410	COG0460	homoserine dehydrogenase
H9N25_RS22415	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H9N25_RS22455	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9N25_RS22460	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9N25_RS22470	COG0649	NAD binding
H9N25_RS22475	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
H9N25_RS22485	COG1034	ATP synthesis coupled electron transport
H9N25_RS22490	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
H9N25_RS22495	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9N25_RS22505	COG0713	ATP synthesis coupled electron transport
H9N25_RS22520	COG1007	ATP synthesis coupled electron transport
H9N25_RS22525	COG0586	Pfam SNARE associated Golgi protein
H9N25_RS22535	COG1253	flavin adenine dinucleotide binding
H9N25_RS22540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H9N25_RS22550	COG0511	ligase activity, forming carbon-carbon bonds
H9N25_RS22555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9N25_RS22565	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9N25_RS22585	COG2353	YceI-like domain
H9N25_RS22610	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
H9N25_RS22645	COG1217	gtp-binding protein TYPA
H9N25_RS22655	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9N25_RS22680	COG0693	protein deglycase activity
H9N25_RS22740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9N25_RS22785	COG0653	protein targeting
H9N25_RS22820	COG0358	DNA primase activity
H9N25_RS22825	COG0792	nuclease activity
H9N25_RS22850	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H9N25_RS22860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H9N25_RS22865	COG2045	Belongs to the ComB family
H9N25_RS22895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H9N25_RS22895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9N25_RS22900	COG1764	response to oxidative stress
H9N25_RS22910	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H9N25_RS22930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H9N25_RS22935	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H9N25_RS22950	COG1278	Cold shock
H9N25_RS22960	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H9N25_RS23010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9N25_RS23025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9N25_RS23035	COG0351	phosphomethylpyrimidine kinase
H9N25_RS23040	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H9N25_RS23045	COG2223	nitrite transmembrane transporter activity
H9N25_RS23105	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H9N25_RS23110	COG1595	DNA-templated transcription, initiation
H9N25_RS23150	COG0477	Major facilitator Superfamily
H9N25_RS23165	COG0384	phenazine biosynthesis protein PhzF
H9N25_RS23175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N25_RS23200	COG4206	TonB-dependent receptor
H9N25_RS23200	COG1629	transport
H9N25_RS23215	COG0640	Transcriptional regulator
H9N25_RS23235	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
H9N25_RS23265	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H9N25_RS23280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9N25_RS23310	COG3279	Response regulator of the LytR AlgR family
H9N25_RS23340	COG0300	oxidoreductase activity
H9N25_RS23345	COG0662	Cupin 2, conserved barrel domain protein
H9N25_RS23345	COG2207	Transcriptional regulator
H9N25_RS23350	COG3275	phosphorelay sensor kinase activity
H9N25_RS23355	COG3279	Response regulator of the LytR AlgR family
H9N25_RS23375	COG0659	secondary active sulfate transmembrane transporter activity
H9N25_RS23385	COG0702	epimerase
H9N25_RS23400	COG4771	TonB-dependent receptor
H9N25_RS23430	COG3291	Pkd domain containing protein
H9N25_RS23450	COG0745	RESPONSE REGULATOR receiver
H9N25_RS23455	COG1609	Transcriptional regulator
H9N25_RS23460	COG4206	TonB-dependent receptor
H9N25_RS23460	COG1629	transport
H9N25_RS23465	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H9N25_RS23475	COG0366	Alpha amylase catalytic
H9N25_RS23480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9N25_RS23485	COG1554	hydrolase, family 65, central catalytic
H9N25_RS23540	COG0825	malonyl-CoA metabolic process
H9N25_RS23555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9N25_RS23560	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H9N25_RS23565	COG0193	aminoacyl-tRNA hydrolase activity
H9N25_RS23580	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H9N25_RS23595	COG0545	Peptidyl-prolyl cis-trans isomerase
H9N25_RS23600	COG0105	UTP biosynthetic process
H9N25_RS23605	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H9N25_RS23610	COG0545	Peptidyl-prolyl cis-trans isomerase
H9N25_RS23630	COG2823	Periplasmic or secreted lipoprotein
H9N25_RS23635	COG2954	triphosphatase activity
H9N25_RS23640	COG3525	Glycosyl hydrolase, family 20, catalytic domain
H9N25_RS23650	COG1012	belongs to the aldehyde dehydrogenase family
H9N25_RS23655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H9N25_RS23670	COG0531	amino acid
H9N25_RS23680	COG4682	membrane
H9N25_RS23685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H9N25_RS23685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H9N25_RS23700	COG1595	DNA-templated transcription, initiation
H9N25_RS23705	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H9N25_RS23715	COG0215	cysteine-tRNA ligase activity
H9N25_RS23720	COG1794	racemase activity, acting on amino acids and derivatives
H9N25_RS23725	COG2234	aminopeptidase activity
H9N25_RS23735	COG0584	glycerophosphoryl diester phosphodiesterase
H9N25_RS23770	COG2226	methyltransferase
H9N25_RS23780	COG0714	Associated with various cellular activities
H9N25_RS23785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9N25_RS23800	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H9N25_RS23820	COG0037	tRNA processing
H9N25_RS23830	COG0438	transferase activity, transferring glycosyl groups
H9N25_RS23835	COG0484	heat shock protein binding
H9N25_RS23850	COG2706	6-phosphogluconolactonase activity
H9N25_RS23855	COG1187	pseudouridine synthase activity
H9N25_RS23875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H9N25_RS23880	COG0084	hydrolase, TatD family'
H9N25_RS23885	COG0252	asparaginase activity
H9N25_RS23890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9N25_RS23890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9N25_RS23895	COG0492	ferredoxin-NADP+ reductase activity
H9N25_RS23905	COG0142	geranyltranstransferase activity
H9N25_RS23915	COG1280	lysine exporter protein (LysE YggA)
H9N25_RS23920	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9N25_RS23935	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H9N25_RS23960	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H9N25_RS23995	COG2353	YceI-like domain
H9N25_RS24005	COG3119	arylsulfatase activity
H9N25_RS24010	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H9N25_RS24010	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H9N25_RS24015	COG1137	ATPase activity
H9N25_RS24035	COG3339	Conserved Protein
H9N25_RS24065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H9N25_RS24080	COG0601	transmembrane transport
H9N25_RS24085	COG2318	DinB family
H9N25_RS24090	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H9N25_RS24095	COG1233	COG1233 Phytoene dehydrogenase and related
H9N25_RS24120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9N25_RS24135	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H9N25_RS24145	COG1216	Glycosyl transferase, family 2
H9N25_RS24165	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H9N25_RS24175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H9N25_RS24180	COG3265	gluconokinase activity
H9N25_RS24200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9N25_RS24215	COG1136	(ABC) transporter
H9N25_RS24215	COG0577	efflux transmembrane transporter activity
H9N25_RS24220	COG0316	Belongs to the HesB IscA family
H9N25_RS24230	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H9N25_RS24230	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly