locus-tag	class	description
Ga0080574_RS00050	COG0542	response to heat
Ga0080574_RS00095	COG0517	IMP dehydrogenase activity
Ga0080574_RS00630	COG0398	Pfam SNARE associated Golgi protein
Ga0080574_RS01060	COG1196	nuclear chromosome segregation
Ga0080574_RS01355	COG1129	ABC transporter
Ga0080574_RS01355	COG0842	Transport permease protein
Ga0080574_RS02195	COG0842	Transport permease protein
Ga0080574_RS02195	COG1129	ABC transporter
Ga0080574_RS02740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Ga0080574_RS03280	COG2132	Multicopper oxidase
Ga0080574_RS03550	COG4962	Type ii secretion system protein e
Ga0080574_RS03575	COG0071	Belongs to the small heat shock protein (HSP20) family
Ga0080574_RS03580	COG0542	response to heat
Ga0080574_RS03600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Ga0080574_RS03605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Ga0080574_RS03610	COG0501	Belongs to the peptidase M48B family
Ga0080574_RS03625	COG4974	Belongs to the 'phage' integrase family
Ga0080574_RS03645	COG0741	lytic transglycosylase activity
Ga0080574_RS03670	COG1192	Involved in chromosome partitioning
Ga0080574_RS03705	COG5489	Protein of unknown function (DUF736)
Ga0080574_RS03730	COG4974	Belongs to the 'phage' integrase family
Ga0080574_RS03735	COG0517	IMP dehydrogenase activity
Ga0080574_RS03745	COG1230	cation diffusion facilitator family transporter
Ga0080574_RS03870	COG1431	PFAM Stem cell self-renewal protein Piwi
Ga0080574_RS03930	COG1104	cysteine desulfurase activity
Ga0080574_RS03955	COG1196	nuclear chromosome segregation
Ga0080574_RS04050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Ga0080574_RS04050	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Ga0080574_RS04060	COG2132	Multicopper oxidase
Ga0080574_RS04065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Ga0080574_RS04065	COG2010	Cytochrome c
Ga0080574_RS04110	COG1230	cation diffusion facilitator family transporter
Ga0080574_RS04115	COG4235	cytochrome complex assembly
Ga0080574_RS04120	COG3088	subunit of a heme lyase
Ga0080574_RS04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Ga0080574_RS04130	COG1138	Cytochrome C-type biogenesis protein
Ga0080574_RS04165	COG0398	Pfam SNARE associated Golgi protein
Ga0080574_RS04210	COG1027	Aspartate ammonia-lyase
Ga0080574_RS04215	COG1129	ABC transporter
Ga0080574_RS04220	COG1172	Belongs to the binding-protein-dependent transport system permease family
Ga0080574_RS04225	COG1879	ABC-type sugar transport system periplasmic component
Ga0080574_RS04230	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
Ga0080574_RS04240	COG0028	Belongs to the TPP enzyme family
Ga0080574_RS04245	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080574_RS04260	COG0583	DNA-binding transcription factor activity
Ga0080574_RS04265	COG0842	Transport permease protein
Ga0080574_RS04270	COG1129	ABC transporter
Ga0080574_RS04270	COG0842	Transport permease protein
Ga0080574_RS04275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ga0080574_RS04290	COG0583	DNA-binding transcription factor activity
Ga0080574_RS04325	COG1960	acyl-CoA dehydrogenase activity
Ga0080574_RS04335	COG1522	sequence-specific DNA binding
Ga0080574_RS04345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080574_RS04370	COG0251	oxidation-reduction process
Ga0080574_RS04375	COG0436	Aminotransferase
Ga0080574_RS04380	COG2186	Transcriptional regulator
Ga0080574_RS04385	COG0372	Belongs to the citrate synthase family
Ga0080574_RS04390	COG0372	Belongs to the citrate synthase family
Ga0080574_RS04420	COG5002	protein histidine kinase activity
Ga0080574_RS04420	COG3850	Histidine kinase
Ga0080574_RS04435	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Ga0080574_RS04440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Ga0080574_RS04455	COG0356	it plays a direct role in the translocation of protons across the membrane
Ga0080574_RS04465	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Ga0080574_RS04465	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Ga0080574_RS04475	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Ga0080574_RS04490	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Ga0080574_RS04505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Ga0080574_RS04525	COG3750	Belongs to the UPF0335 family
Ga0080574_RS04535	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Ga0080574_RS04560	COG3179	chitinase
Ga0080574_RS04675	COG4695	Portal protein
Ga0080574_RS04840	COG2801	Transposase and inactivated derivatives
Ga0080574_RS04855	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ga0080574_RS04855	COG1024	Enoyl-CoA hydratase
Ga0080574_RS04900	COG5002	protein histidine kinase activity
Ga0080574_RS04910	COG0745	RESPONSE REGULATOR receiver
Ga0080574_RS04940	COG0410	ABC transporter
Ga0080574_RS04945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Ga0080574_RS04955	COG0511	ligase activity, forming carbon-carbon bonds
Ga0080574_RS04960	COG0439	Biotin carboxylase
Ga0080574_RS04965	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Ga0080574_RS04990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Ga0080574_RS04995	COG0564	pseudouridine synthase activity
Ga0080574_RS05010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Ga0080574_RS05020	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Ga0080574_RS05020	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Ga0080574_RS05025	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Ga0080574_RS05030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Ga0080574_RS05060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Ga0080574_RS05060	COG2124	cytochrome p450
Ga0080574_RS05075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Ga0080574_RS05080	COG0789	Transcriptional regulator
Ga0080574_RS05085	COG0583	DNA-binding transcription factor activity
Ga0080574_RS05100	COG0789	Transcriptional regulator
Ga0080574_RS05105	COG2258	MOSC domain
Ga0080574_RS05110	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
Ga0080574_RS05115	COG3485	protocatechuate 3,4-dioxygenase
Ga0080574_RS05120	COG1172	Belongs to the binding-protein-dependent transport system permease family
Ga0080574_RS05125	COG1129	ABC transporter
Ga0080574_RS05140	COG0402	S-adenosylhomocysteine deaminase activity
Ga0080574_RS05150	COG1454	alcohol dehydrogenase
Ga0080574_RS05160	COG0583	DNA-binding transcription factor activity
Ga0080574_RS05180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Ga0080574_RS05195	COG0719	Fe-S assembly protein
Ga0080574_RS05200	COG0396	ATPase activity
Ga0080574_RS05210	COG0393	Putative heavy-metal-binding
Ga0080574_RS05220	COG0719	Fe-S assembly protein
Ga0080574_RS05230	COG1959	2 iron, 2 sulfur cluster binding
Ga0080574_RS05235	COG2945	thiolester hydrolase activity
Ga0080574_RS05255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Ga0080574_RS05265	COG0477	Major facilitator Superfamily
Ga0080574_RS05270	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Ga0080574_RS05280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Ga0080574_RS05285	COG2833	Protein of unknown function (DUF455)
Ga0080574_RS05290	COG0739	heme binding
Ga0080574_RS05300	COG3842	ATPase activity
Ga0080574_RS05305	COG1840	ABC-type Fe3 transport system, periplasmic component
Ga0080574_RS05310	COG1178	ABC-type Fe3 transport system permease component
Ga0080574_RS05315	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Ga0080574_RS05335	COG3639	organic phosphonate transmembrane transporter activity
Ga0080574_RS05340	COG3639	organic phosphonate transmembrane transporter activity
Ga0080574_RS05350	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Ga0080574_RS05360	COG4106	trans-aconitate 2-methyltransferase activity
Ga0080574_RS05365	COG0489	protein tyrosine kinase activity
Ga0080574_RS05375	COG0525	valine-tRNA ligase activity
Ga0080574_RS05385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Ga0080574_RS05395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Ga0080574_RS05400	COG1121	(ABC) transporter
Ga0080574_RS05405	COG0735	belongs to the Fur family
Ga0080574_RS05420	COG0133	tryptophan synthase activity
Ga0080574_RS05425	COG1305	Transglutaminase-like
Ga0080574_RS05435	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Ga0080574_RS05440	COG1984	allophanate hydrolase subunit 2
Ga0080574_RS05445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Ga0080574_RS05455	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Ga0080574_RS05460	COG1530	ribonuclease E activity
Ga0080574_RS05465	COG0424	maF-like protein
Ga0080574_RS05475	COG3153	acetyltransferase
Ga0080574_RS05475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Ga0080574_RS05505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Ga0080574_RS05515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Ga0080574_RS05530	COG1902	pentaerythritol trinitrate reductase activity
Ga0080574_RS05530	COG0446	pyridine nucleotide-disulphide oxidoreductase
Ga0080574_RS05540	COG0028	Belongs to the TPP enzyme family
Ga0080574_RS05550	COG0745	RESPONSE REGULATOR receiver
Ga0080574_RS05560	COG0835	chemotaxis
Ga0080574_RS05565	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Ga0080574_RS05570	COG0745	RESPONSE REGULATOR receiver
Ga0080574_RS05580	COG2201	protein-glutamate methylesterase activity
Ga0080574_RS05585	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Ga0080574_RS05605	COG2308	Evidence 4 Homologs of previously reported genes of
Ga0080574_RS05615	COG0559	Belongs to the binding-protein-dependent transport system permease family
Ga0080574_RS05645	COG0395	ABC-type sugar transport system, permease component
Ga0080574_RS05650	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
Ga0080574_RS05665	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Ga0080574_RS05685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Ga0080574_RS05690	COG1120	ATPase activity
Ga0080574_RS05695	COG0811	peptide transport
Ga0080574_RS05715	COG0084	hydrolase, TatD family'
Ga0080574_RS05735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Ga0080574_RS05750	COG0069	glutamate synthase activity
Ga0080574_RS05755	COG2218	PFAM glutamate synthase alpha subunit domain protein
Ga0080574_RS05760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Ga0080574_RS05795	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Ga0080574_RS05800	COG0513	Belongs to the DEAD box helicase family
Ga0080574_RS05805	COG0154	amidase activity
Ga0080574_RS05815	COG4172	Belongs to the ABC transporter superfamily
Ga0080574_RS05820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080574_RS05825	COG0601	transmembrane transport
Ga0080574_RS05830	COG0747	negative chemotaxis
Ga0080574_RS05835	COG0235	Class ii aldolase
Ga0080574_RS05850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080574_RS05855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Ga0080574_RS05880	COG0747	negative chemotaxis
Ga0080574_RS05885	COG0601	transmembrane transport
Ga0080574_RS05890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080574_RS05895	COG0444	Belongs to the ABC transporter superfamily
Ga0080574_RS05915	COG3707	response regulator
Ga0080574_RS05920	COG1116	anion transmembrane transporter activity
Ga0080574_RS05920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ga0080574_RS05925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ga0080574_RS05925	COG1116	anion transmembrane transporter activity
Ga0080574_RS05930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ga0080574_RS05935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ga0080574_RS05935	COG1116	anion transmembrane transporter activity
Ga0080574_RS05945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Ga0080574_RS05950	COG2146	nitrite reductase [NAD(P)H] activity
Ga0080574_RS05955	COG0243	molybdopterin cofactor binding
Ga0080574_RS05980	COG2801	Transposase and inactivated derivatives
Ga0080574_RS06015	COG0587	DNA-directed DNA polymerase activity
Ga0080574_RS06025	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Ga0080574_RS06035	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Ga0080574_RS06040	COG0849	cell division
Ga0080574_RS06045	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Ga0080574_RS06050	COG1181	Belongs to the D-alanine--D-alanine ligase family
Ga0080574_RS06055	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Ga0080574_RS06065	COG0531	amino acid
Ga0080574_RS06070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Ga0080574_RS06075	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Ga0080574_RS06085	COG2081	HI0933 family
Ga0080574_RS06095	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Ga0080574_RS06100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Ga0080574_RS06110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Ga0080574_RS06125	COG0275	rRNA processing
Ga0080574_RS06130	COG2001	Belongs to the MraZ family
Ga0080574_RS06140	COG1519	Transferase
Ga0080574_RS06150	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080574_RS06165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Ga0080574_RS06190	COG0659	secondary active sulfate transmembrane transporter activity
Ga0080574_RS06195	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Ga0080574_RS06215	COG3243	poly(R)-hydroxyalkanoic acid synthase
Ga0080574_RS06235	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Ga0080574_RS06245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Ga0080574_RS06250	COG0758	DNA mediated transformation
Ga0080574_RS06260	COG0312	modulator of DNA gyrase
Ga0080574_RS06270	COG0109	protoheme IX farnesyltransferase activity
Ga0080574_RS06275	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Ga0080574_RS06290	COG0686	Belongs to the AlaDH PNT family
Ga0080574_RS06310	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Ga0080574_RS06315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Ga0080574_RS06340	COG1366	Belongs to the anti-sigma-factor antagonist family
Ga0080574_RS06345	COG0183	Belongs to the thiolase family
Ga0080574_RS06360	COG0564	pseudouridine synthase activity
Ga0080574_RS06370	COG0450	alkyl hydroperoxide reductase
Ga0080574_RS06390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Ga0080574_RS06395	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Ga0080574_RS06400	COG3237	CsbD-like
Ga0080574_RS06405	COG0346	lactoylglutathione lyase activity
Ga0080574_RS06420	COG0280	phosphate acetyltransferase
Ga0080574_RS06420	COG0281	malic enzyme
Ga0080574_RS06430	COG1227	inorganic diphosphatase activity
Ga0080574_RS06440	COG0659	secondary active sulfate transmembrane transporter activity
Ga0080574_RS06445	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080574_RS06450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Ga0080574_RS06465	COG0321	lipoyl(octanoyl) transferase activity
Ga0080574_RS06500	COG1610	YqeY-like protein
Ga0080574_RS06505	COG0505	Belongs to the CarA family
Ga0080574_RS06515	COG1802	Transcriptional regulator
Ga0080574_RS06560	COG1346	cytolysis
Ga0080574_RS06570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Ga0080574_RS06575	COG0752	glycyl-tRNA synthetase alpha subunit
Ga0080574_RS06580	COG0751	glycine-tRNA ligase activity
Ga0080574_RS06585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Ga0080574_RS06585	COG0574	Belongs to the PEP-utilizing enzyme family
Ga0080574_RS06590	COG3773	Cell wall hydrolase
Ga0080574_RS06590	COG3409	Peptidoglycan-binding domain 1 protein
Ga0080574_RS06600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Ga0080574_RS06605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Ga0080574_RS06615	COG0442	prolyl-tRNA aminoacylation
Ga0080574_RS06620	COG0628	permease
Ga0080574_RS06630	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Ga0080574_RS06640	COG0248	Ppx GppA phosphatase
Ga0080574_RS06650	COG0116	Belongs to the methyltransferase superfamily
Ga0080574_RS06655	COG0107	imidazoleglycerol-phosphate synthase activity
Ga0080574_RS06660	COG0140	phosphoribosyl-ATP diphosphatase activity
Ga0080574_RS06665	COG1832	CoA-binding protein
Ga0080574_RS06705	COG0504	CTP synthase activity
Ga0080574_RS06710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Ga0080574_RS06720	COG1253	flavin adenine dinucleotide binding
Ga0080574_RS06725	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Ga0080574_RS06730	COG1702	phosphate starvation-inducible protein PhoH
Ga0080574_RS06745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Ga0080574_RS06770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Ga0080574_RS06775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Ga0080574_RS06780	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Ga0080574_RS06785	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Ga0080574_RS06790	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Ga0080574_RS06800	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Ga0080574_RS06815	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Ga0080574_RS06815	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Ga0080574_RS06830	COG4770	biotin carboxylase activity
Ga0080574_RS06855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Ga0080574_RS06860	COG2814	Major facilitator Superfamily
Ga0080574_RS06865	COG1396	sequence-specific DNA binding
Ga0080574_RS06865	COG3800	Transcriptional regulator
Ga0080574_RS06870	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Ga0080574_RS06875	COG0154	amidase activity
Ga0080574_RS06890	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Ga0080574_RS06900	COG2873	o-acetylhomoserine
Ga0080574_RS06910	COG2968	Membrane
Ga0080574_RS06920	COG0210	DNA helicase
Ga0080574_RS06930	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Ga0080574_RS06960	COG0811	peptide transport
Ga0080574_RS06980	COG1629	transport
Ga0080574_RS06985	COG3720	iron ion transport
Ga0080574_RS06995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Ga0080574_RS07000	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Ga0080574_RS07005	COG2329	Antibiotic biosynthesis monooxygenase
Ga0080574_RS07010	COG0435	Glutathione S-transferase
Ga0080574_RS07015	COG3384	dioxygenase
Ga0080574_RS07030	COG0583	DNA-binding transcription factor activity
Ga0080574_RS07035	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Ga0080574_RS07065	COG4215	(ABC) transporter
Ga0080574_RS07070	COG4160	amino acid transport
Ga0080574_RS07075	COG0174	glutamine synthetase
Ga0080574_RS07080	COG0519	Catalyzes the synthesis of GMP from XMP
Ga0080574_RS07080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Ga0080574_RS07085	COG0174	glutamine synthetase
Ga0080574_RS07090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080574_RS07095	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Ga0080574_RS07105	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Ga0080574_RS07110	COG0740	serine-type endopeptidase activity
Ga0080574_RS07140	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Ga0080574_RS07145	COG0737	Belongs to the 5'-nucleotidase family
Ga0080574_RS07150	COG3258	Cytochrome c
Ga0080574_RS07175	COG0785	Cytochrome C biogenesis protein
Ga0080574_RS07190	COG2391	methyltransferase activity
Ga0080574_RS07215	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Ga0080574_RS07220	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Ga0080574_RS07225	COG0783	Belongs to the Dps family
Ga0080574_RS07265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Ga0080574_RS07270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Ga0080574_RS07275	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Ga0080574_RS07280	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Ga0080574_RS07295	COG1194	a g-specific adenine glycosylase
Ga0080574_RS07305	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Ga0080574_RS07310	COG3346	SURF1 family
Ga0080574_RS07320	COG0612	Peptidase, M16
Ga0080574_RS07325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Ga0080574_RS07350	COG0739	heme binding
Ga0080574_RS07350	COG0741	lytic transglycosylase activity
Ga0080574_RS07350	COG1196	nuclear chromosome segregation
Ga0080574_RS07370	COG4964	Belongs to the GSP D family
Ga0080574_RS07380	COG2894	cell division
Ga0080574_RS07465	COG2099	Precorrin-6x reductase
Ga0080574_RS07480	COG2875	Belongs to the precorrin methyltransferase family
Ga0080574_RS07485	COG1797	cobyrinic acid a,c-diamide synthase activity
Ga0080574_RS07490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Ga0080574_RS07490	COG1648	precorrin-2 dehydrogenase activity
Ga0080574_RS07515	COG0310	cobalt ion transport
Ga0080574_RS07535	COG1535	isochorismatase
Ga0080574_RS07535	COG3433	isochorismatase activity
Ga0080574_RS07540	COG1021	2,3-dihydroxybenzoate-AMP ligase
Ga0080574_RS07550	COG2819	hydrolase of the alpha beta superfamily
Ga0080574_RS07555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Ga0080574_RS07560	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080574_RS07575	COG0529	Catalyzes the synthesis of activated sulfate
Ga0080574_RS07575	COG2046	Belongs to the sulfate adenylyltransferase family
Ga0080574_RS07580	COG0492	ferredoxin-NADP+ reductase activity
Ga0080574_RS07585	COG1522	sequence-specific DNA binding
Ga0080574_RS07595	COG1496	oxidoreductase activity
Ga0080574_RS07605	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Ga0080574_RS07615	COG0200	Binds to the 23S rRNA
Ga0080574_RS07620	COG0201	protein transport
Ga0080574_RS07625	COG0563	adenylate kinase activity
Ga0080574_RS07640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Ga0080574_RS07645	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Ga0080574_RS07650	COG0202	RNA polymerase activity
Ga0080574_RS07670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Ga0080574_RS07675	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Ga0080574_RS07685	COG0564	pseudouridine synthase activity
Ga0080574_RS07690	COG0546	phosphoglycolate phosphatase activity
Ga0080574_RS07700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Ga0080574_RS07705	COG4597	amino acid ABC transporter
Ga0080574_RS07710	COG0765	amino acid transport
Ga0080574_RS07715	COG1126	abc transporter atp-binding protein
Ga0080574_RS07720	COG1841	ribosomal large subunit assembly
Ga0080574_RS07725	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Ga0080574_RS07730	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Ga0080574_RS07735	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Ga0080574_RS07740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Ga0080574_RS07745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Ga0080574_RS07750	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Ga0080574_RS07755	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Ga0080574_RS07765	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Ga0080574_RS07770	COG0255	Belongs to the universal ribosomal protein uL29 family
Ga0080574_RS07790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Ga0080574_RS07795	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Ga0080574_RS07800	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Ga0080574_RS07805	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Ga0080574_RS07810	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Ga0080574_RS07820	COG0089	rRNA binding
Ga0080574_RS07825	COG0088	Forms part of the polypeptide exit tunnel
Ga0080574_RS07830	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Ga0080574_RS07835	COG0051	transcription antitermination factor activity, RNA binding
Ga0080574_RS07840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Ga0080574_RS07845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Ga0080574_RS07850	COG0049	tRNA binding
Ga0080574_RS07855	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Ga0080574_RS07875	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Ga0080574_RS07880	COG0085	RNA polymerase activity
Ga0080574_RS07885	COG0222	ribosome binding
Ga0080574_RS07890	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Ga0080574_RS07895	COG0081	regulation of translation
Ga0080574_RS07900	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Ga0080574_RS07905	COG3214	Protein conserved in bacteria
Ga0080574_RS07910	COG0250	Participates in transcription elongation, termination and antitermination
Ga0080574_RS07945	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Ga0080574_RS07965	COG0745	RESPONSE REGULATOR receiver
Ga0080574_RS07990	COG0688	phosphatidylethanolamine metabolic process
Ga0080574_RS07995	COG1183	phosphatidylcholine synthase activity
Ga0080574_RS08000	COG2824	Alkylphosphonate utilization operon protein PhnA
Ga0080574_RS08025	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Ga0080574_RS08035	COG4143	(ABC) transporter
Ga0080574_RS08040	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Ga0080574_RS08045	COG0840	transmembrane signaling receptor activity
Ga0080574_RS08060	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Ga0080574_RS08065	COG0459	protein refolding
Ga0080574_RS08070	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Ga0080574_RS08075	COG0697	spore germination
Ga0080574_RS08090	COG0339	signal peptide processing
Ga0080574_RS08095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Ga0080574_RS08100	COG0756	dUTP diphosphatase activity
Ga0080574_RS08105	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Ga0080574_RS08125	COG0606	chelatase, subunit chli
Ga0080574_RS08130	COG0657	acetylesterase activity
Ga0080574_RS08140	COG0792	nuclease activity
Ga0080574_RS08145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Ga0080574_RS08155	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Ga0080574_RS08180	COG0180	Tryptophanyl-tRNA synthetase
Ga0080574_RS08185	COG1686	Belongs to the peptidase S11 family
Ga0080574_RS08195	COG0697	spore germination
Ga0080574_RS08200	COG2391	methyltransferase activity
Ga0080574_RS08205	COG0662	Cupin 2, conserved barrel domain protein
Ga0080574_RS08215	COG2264	protein methyltransferase activity
Ga0080574_RS08235	COG0632	four-way junction helicase activity
Ga0080574_RS08240	COG2255	four-way junction helicase activity
Ga0080574_RS08245	COG1686	Belongs to the peptidase S11 family
Ga0080574_RS08255	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Ga0080574_RS08270	COG0408	coproporphyrinogen oxidase activity
Ga0080574_RS08285	COG0784	Response regulator, receiver
Ga0080574_RS08285	COG2205	protein histidine kinase activity
Ga0080574_RS08285	COG5002	protein histidine kinase activity
Ga0080574_RS08300	COG0840	transmembrane signaling receptor activity
Ga0080574_RS08320	COG0745	RESPONSE REGULATOR receiver
Ga0080574_RS08325	COG0435	Glutathione S-transferase
Ga0080574_RS08340	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Ga0080574_RS08345	COG1079	Belongs to the binding-protein-dependent transport system permease family
Ga0080574_RS08355	COG4603	Belongs to the binding-protein-dependent transport system permease family
Ga0080574_RS08360	COG3845	ABC transporter
Ga0080574_RS08365	COG1744	ABC transporter substrate-binding protein PnrA-like
Ga0080574_RS08375	COG1214	PFAM Peptidase M22, glycoprotease
Ga0080574_RS08380	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Ga0080574_RS08400	COG0322	excinuclease ABC activity
Ga0080574_RS08420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Ga0080574_RS08420	COG0616	signal peptide processing
Ga0080574_RS08430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Ga0080574_RS08445	COG1192	Involved in chromosome partitioning
Ga0080574_RS08475	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Ga0080574_RS08490	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Ga0080574_RS08495	COG0840	transmembrane signaling receptor activity
Ga0080574_RS08500	COG0488	(ABC) transporter
Ga0080574_RS08505	COG1278	Cold shock
Ga0080574_RS08515	COG0644	oxidoreductase
Ga0080574_RS08520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Ga0080574_RS08530	COG0725	ABC transporter, periplasmic molybdate-binding protein
Ga0080574_RS08535	COG4149	molybdate abc transporter
Ga0080574_RS08540	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Ga0080574_RS08545	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Ga0080574_RS08560	COG0463	Glycosyl transferase, family 2
Ga0080574_RS08585	COG0842	Transport permease protein
Ga0080574_RS08590	COG1131	(ABC) transporter
Ga0080574_RS08605	COG3243	poly(R)-hydroxyalkanoic acid synthase
Ga0080574_RS08625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Ga0080574_RS08635	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Ga0080574_RS08640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Ga0080574_RS08650	COG0469	pyruvate kinase activity
Ga0080574_RS08675	COG0457	Tetratricopeptide repeat
Ga0080574_RS08685	COG0196	riboflavin kinase activity
Ga0080574_RS08690	COG2983	Belongs to the UPF0260 family
Ga0080574_RS08725	COG1674	ftsk spoiiie
Ga0080574_RS08730	COG0436	Aminotransferase
Ga0080574_RS08740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Ga0080574_RS08750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Ga0080574_RS08765	COG1024	Enoyl-CoA hydratase
Ga0080574_RS08780	COG0667	Aldo Keto reductase
Ga0080574_RS08785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Ga0080574_RS08795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Ga0080574_RS08810	COG1047	Peptidyl-prolyl cis-trans
Ga0080574_RS08815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Ga0080574_RS08820	COG0596	Alpha beta hydrolase
Ga0080574_RS08825	COG0640	Transcriptional regulator
Ga0080574_RS08830	COG0318	PFAM AMP-dependent synthetase and ligase
Ga0080574_RS08835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Ga0080574_RS08850	COG1846	Transcriptional regulator
Ga0080574_RS08860	COG0737	Belongs to the 5'-nucleotidase family
Ga0080574_RS08875	COG1309	transcriptional regulator
Ga0080574_RS08890	COG0167	dihydroorotate dehydrogenase activity
Ga0080574_RS08900	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Ga0080574_RS08905	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Ga0080574_RS08940	COG1022	Amp-dependent synthetase and ligase
Ga0080574_RS08955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080574_RS08970	COG0730	response to heat
Ga0080574_RS08985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ga0080574_RS08990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Ga0080574_RS08995	COG0583	DNA-binding transcription factor activity
Ga0080574_RS09000	COG0450	alkyl hydroperoxide reductase
Ga0080574_RS09005	COG0783	Belongs to the Dps family
Ga0080574_RS09010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Ga0080574_RS09010	COG3453	Protein conserved in bacteria
Ga0080574_RS09015	COG0765	amino acid transport
Ga0080574_RS09020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Ga0080574_RS09025	COG0765	amino acid transport
Ga0080574_RS09030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Ga0080574_RS09030	COG0072	phenylalanine-tRNA ligase activity
Ga0080574_RS09035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Ga0080574_RS09050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Ga0080574_RS09060	COG0681	Belongs to the peptidase S26 family
Ga0080574_RS09065	COG0571	ribonuclease III activity
Ga0080574_RS09070	COG0697	spore germination
Ga0080574_RS09075	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Ga0080574_RS09090	COG4106	trans-aconitate 2-methyltransferase activity
Ga0080574_RS09095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Ga0080574_RS09100	COG0037	tRNA processing
Ga0080574_RS09110	COG2885	chlorophyll binding
Ga0080574_RS09115	COG0823	Involved in the tonB-independent uptake of proteins
Ga0080574_RS09135	COG0824	Thioesterase
Ga0080574_RS09145	COG0495	leucyl-tRNA aminoacylation
Ga0080574_RS09170	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Ga0080574_RS09175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Ga0080574_RS09180	COG0181	hydroxymethylbilane synthase activity
Ga0080574_RS09205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Ga0080574_RS09215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Ga0080574_RS09220	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Ga0080574_RS09305	COG2197	response regulator
Ga0080574_RS09310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Ga0080574_RS09335	COG1216	Glycosyl transferase, family 2
Ga0080574_RS09340	COG1216	Glycosyl transferase, family 2
Ga0080574_RS09345	COG0438	transferase activity, transferring glycosyl groups
Ga0080574_RS09350	COG0730	response to heat
Ga0080574_RS09355	COG1802	Transcriptional regulator
Ga0080574_RS09365	COG0601	transmembrane transport
Ga0080574_RS09370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080574_RS09375	COG0444	Belongs to the ABC transporter superfamily
Ga0080574_RS09380	COG4608	Belongs to the ABC transporter superfamily
Ga0080574_RS09385	COG0405	Gamma-glutamyltransferase
Ga0080574_RS09390	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
Ga0080574_RS09400	COG2943	transferase activity, transferring hexosyl groups
Ga0080574_RS09415	COG1177	transmembrane transport
Ga0080574_RS09420	COG1176	ABC-type spermidine putrescine transport system, permease component I
Ga0080574_RS09425	COG3842	ATPase activity
Ga0080574_RS09430	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Ga0080574_RS09435	COG1414	Transcriptional regulator
Ga0080574_RS09445	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080574_RS09455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Ga0080574_RS09460	COG1803	Methylglyoxal synthase
Ga0080574_RS09465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080574_RS09470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Ga0080574_RS09475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Ga0080574_RS09480	COG1121	(ABC) transporter
Ga0080574_RS09495	COG1492	cobalamin metabolic process
Ga0080574_RS09505	COG4607	ABC-type enterochelin transport system periplasmic component
Ga0080574_RS09510	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Ga0080574_RS09515	COG4605	iron ion homeostasis
Ga0080574_RS09520	COG4604	ABC transporter, ATP-binding protein
Ga0080574_RS09525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080574_RS09535	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080574_RS09545	COG4221	oxidoreductase activity
Ga0080574_RS09560	COG3436	PFAM IS66 Orf2 family protein
Ga0080574_RS09565	COG2433	Pfam Transposase IS66
Ga0080574_RS09585	COG0318	PFAM AMP-dependent synthetase and ligase
Ga0080574_RS09630	COG1960	acyl-CoA dehydrogenase activity
Ga0080574_RS09635	COG1024	Enoyl-CoA hydratase
Ga0080574_RS09635	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ga0080574_RS09640	COG0318	PFAM AMP-dependent synthetase and ligase
Ga0080574_RS09645	COG0183	Belongs to the thiolase family
Ga0080574_RS09660	COG2963	transposase activity
Ga0080574_RS09665	COG3436	PFAM IS66 Orf2 family protein
Ga0080574_RS09670	COG4372	Transposase
Ga0080574_RS09675	COG3012	SEC-C Motif Domain Protein
Ga0080574_RS09685	COG2433	Pfam Transposase IS66
Ga0080574_RS09690	COG3436	PFAM IS66 Orf2 family protein
Ga0080574_RS09750	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080574_RS09755	COG2814	Major facilitator Superfamily
Ga0080574_RS09760	COG2207	Transcriptional regulator
Ga0080574_RS09775	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080574_RS09790	COG4221	oxidoreductase activity
Ga0080574_RS09820	COG3328	transposase activity
Ga0080574_RS09830	COG0583	DNA-binding transcription factor activity
Ga0080574_RS09840	COG2948	multi-organism process
Ga0080574_RS09855	COG3846	protein secretion by the type IV secretion system
Ga0080574_RS09885	COG4962	Type ii secretion system protein e
Ga0080574_RS09925	COG0741	lytic transglycosylase activity
Ga0080574_RS09950	COG1192	Involved in chromosome partitioning
Ga0080574_RS09985	COG5489	Protein of unknown function (DUF736)
Ga0080574_RS09995	COG2223	nitrite transmembrane transporter activity
Ga0080574_RS10000	COG0583	DNA-binding transcription factor activity
Ga0080574_RS10010	COG4221	oxidoreductase activity
Ga0080574_RS10170	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Ga0080574_RS10175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Ga0080574_RS10180	COG0069	glutamate synthase activity
Ga0080574_RS10190	COG0542	response to heat
Ga0080574_RS10195	COG0284	orotidine-5'-phosphate decarboxylase activity
Ga0080574_RS10210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Ga0080574_RS10225	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Ga0080574_RS10235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Ga0080574_RS10245	COG1802	Transcriptional regulator
Ga0080574_RS10255	COG3842	ATPase activity
Ga0080574_RS10260	COG1176	ABC-type spermidine putrescine transport system, permease component I
Ga0080574_RS10265	COG1177	transmembrane transport
Ga0080574_RS10270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080574_RS10275	COG3046	protein related to deoxyribodipyrimidine photolyase
Ga0080574_RS10295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Ga0080574_RS10325	COG1253	flavin adenine dinucleotide binding
Ga0080574_RS10375	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Ga0080574_RS10380	COG0285	dihydrofolate synthase activity
Ga0080574_RS10395	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Ga0080574_RS10400	COG2271	Major facilitator Superfamily
Ga0080574_RS10405	COG2423	ornithine cyclodeaminase activity
Ga0080574_RS10415	COG1671	Belongs to the UPF0178 family
Ga0080574_RS10420	COG0679	Auxin Efflux Carrier
Ga0080574_RS10430	COG1131	(ABC) transporter
Ga0080574_RS10455	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
Ga0080574_RS10465	COG0714	Associated with various cellular activities
Ga0080574_RS10485	COG0791	NLP P60 protein
Ga0080574_RS10490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Ga0080574_RS10500	COG0288	reversible hydration of carbon dioxide
Ga0080574_RS10515	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Ga0080574_RS10530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Ga0080574_RS10550	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Ga0080574_RS10555	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Ga0080574_RS10570	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Ga0080574_RS10580	COG0346	lactoylglutathione lyase activity
Ga0080574_RS10595	COG0778	Nitroreductase
Ga0080574_RS10605	COG1872	DUF167
Ga0080574_RS10705	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080574_RS10715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Ga0080574_RS10785	COG1414	Transcriptional regulator
Ga0080574_RS10795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Ga0080574_RS10805	COG0583	DNA-binding transcription factor activity
Ga0080574_RS10810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Ga0080574_RS10815	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Ga0080574_RS10820	COG3485	protocatechuate 3,4-dioxygenase
Ga0080574_RS10825	COG3485	protocatechuate 3,4-dioxygenase
Ga0080574_RS10835	COG0737	Belongs to the 5'-nucleotidase family
Ga0080574_RS10860	COG0277	FAD linked oxidase domain protein
Ga0080574_RS10865	COG0277	FAD linked oxidase domain protein
Ga0080574_RS10875	COG0247	lactate metabolic process
Ga0080574_RS10880	COG3591	Belongs to the peptidase S1B family
Ga0080574_RS10890	COG0071	Belongs to the small heat shock protein (HSP20) family
Ga0080574_RS10945	COG0437	4 iron, 4 sulfur cluster binding
Ga0080574_RS10950	COG0243	molybdopterin cofactor binding
Ga0080574_RS10965	COG0438	transferase activity, transferring glycosyl groups
Ga0080574_RS10970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Ga0080574_RS10970	COG2755	lipolytic protein G-D-S-L family
Ga0080574_RS10975	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Ga0080574_RS10980	COG4221	oxidoreductase activity
Ga0080574_RS10990	COG0673	inositol 2-dehydrogenase activity
Ga0080574_RS11000	COG0297	glycogen (starch) synthase activity
Ga0080574_RS11000	COG0438	transferase activity, transferring glycosyl groups
Ga0080574_RS11010	COG0673	inositol 2-dehydrogenase activity
Ga0080574_RS11015	COG0489	protein tyrosine kinase activity
Ga0080574_RS11055	COG0438	transferase activity, transferring glycosyl groups
Ga0080574_RS11060	COG4608	Belongs to the ABC transporter superfamily
Ga0080574_RS11065	COG0444	Belongs to the ABC transporter superfamily
Ga0080574_RS11075	COG0747	negative chemotaxis
Ga0080574_RS11100	COG0463	Glycosyl transferase, family 2
Ga0080574_RS11120	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Ga0080574_RS11120	COG0517	IMP dehydrogenase activity
Ga0080574_RS11125	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Ga0080574_RS11130	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Ga0080574_RS11135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Ga0080574_RS11170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Ga0080574_RS11175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Ga0080574_RS11180	COG2350	Protein conserved in bacteria
Ga0080574_RS11200	COG1115	amino acid carrier protein
Ga0080574_RS11215	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Ga0080574_RS11225	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Ga0080574_RS11240	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Ga0080574_RS11245	COG1999	signal sequence binding
Ga0080574_RS11255	COG2205	protein histidine kinase activity
Ga0080574_RS11260	COG0802	atpase or kinase
Ga0080574_RS11265	COG3178	'Phosphotransferase
Ga0080574_RS11270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Ga0080574_RS11280	COG1074	ATP-dependent DNA helicase activity
Ga0080574_RS11290	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Ga0080574_RS11290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Ga0080574_RS11295	COG0509	glycine decarboxylation via glycine cleavage system
Ga0080574_RS11300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Ga0080574_RS11305	COG1959	2 iron, 2 sulfur cluster binding
Ga0080574_RS11320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Ga0080574_RS11330	COG1234	tRNA 3'-trailer cleavage
Ga0080574_RS11355	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Ga0080574_RS11365	COG1597	lipid kinase activity
Ga0080574_RS11370	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Ga0080574_RS11400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Ga0080574_RS11410	COG0488	(ABC) transporter
Ga0080574_RS11415	COG1278	Cold shock
Ga0080574_RS11435	COG2226	methyltransferase
Ga0080574_RS11460	COG3034	peptidoglycan biosynthetic process
Ga0080574_RS11465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Ga0080574_RS11475	COG1132	(ABC) transporter
Ga0080574_RS11480	COG1132	(ABC) transporter
Ga0080574_RS11505	COG0494	nUDIX hydrolase
Ga0080574_RS11520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Ga0080574_RS11530	COG0137	argininosuccinate synthase activity
Ga0080574_RS11555	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Ga0080574_RS11560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Ga0080574_RS11565	COG0280	phosphate acetyltransferase
Ga0080574_RS11565	COG0281	malic enzyme
Ga0080574_RS11570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Ga0080574_RS11575	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Ga0080574_RS11580	COG1420	regulation of RNA biosynthetic process
Ga0080574_RS11585	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Ga0080574_RS11590	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Ga0080574_RS11595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Ga0080574_RS11610	COG0357	Ribosomal RNA small subunit methyltransferase G
Ga0080574_RS11615	COG0445	tRNA wobble uridine modification
Ga0080574_RS11620	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Ga0080574_RS11625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Ga0080574_RS11630	COG0424	maF-like protein
Ga0080574_RS11635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Ga0080574_RS11640	COG0237	dephospho-CoA kinase activity
Ga0080574_RS11645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Ga0080574_RS11650	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Ga0080574_RS11655	COG3030	protein affecting phage T7 exclusion by the F plasmid
Ga0080574_RS11670	COG2840	Smr protein MutS2
Ga0080574_RS11675	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Ga0080574_RS11680	COG3474	cytochrome
Ga0080574_RS11700	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Ga0080574_RS11705	COG1360	Flagellar Motor Protein
Ga0080574_RS11725	COG1706	bacterial-type flagellum-dependent cell motility
Ga0080574_RS11730	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Ga0080574_RS11745	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Ga0080574_RS11755	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Ga0080574_RS11775	COG4786	Flagellar basal body rod
Ga0080574_RS11780	COG4786	Flagellar basal body rod
Ga0080574_RS11785	COG1987	bacterial-type flagellum assembly
Ga0080574_RS11790	COG1677	Flagellar hook-basal body complex protein FliE
Ga0080574_RS11795	COG1558	bacterial-type flagellum-dependent cell motility
Ga0080574_RS11800	COG1815	bacterial-type flagellum-dependent cell motility
Ga0080574_RS11815	COG5443	negative regulation of bacterial-type flagellum assembly
Ga0080574_RS11845	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Ga0080574_RS11850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Ga0080574_RS11860	COG2226	methyltransferase
Ga0080574_RS11865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Ga0080574_RS11870	COG1024	Enoyl-CoA hydratase
Ga0080574_RS11880	COG0268	Binds directly to 16S ribosomal RNA
Ga0080574_RS11885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Ga0080574_RS11895	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Ga0080574_RS11920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Ga0080574_RS11935	COG0628	permease
Ga0080574_RS11940	COG1295	ribonuclease BN
Ga0080574_RS11970	COG0438	transferase activity, transferring glycosyl groups
Ga0080574_RS11975	COG0483	inositol monophosphate 1-phosphatase activity
Ga0080574_RS11985	COG4181	ATPase activity
Ga0080574_RS12000	COG1376	ErfK ybiS ycfS ynhG family protein
Ga0080574_RS12005	COG3118	belongs to the thioredoxin family
Ga0080574_RS12025	COG1766	The M ring may be actively involved in energy transduction
Ga0080574_RS12035	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Ga0080574_RS12040	COG1338	Plays a role in the flagellum-specific transport system
Ga0080574_RS12045	COG1054	Belongs to the UPF0176 family
Ga0080574_RS12050	COG1335	isochorismatase
Ga0080574_RS12055	COG5002	protein histidine kinase activity
Ga0080574_RS12055	COG2198	Histidine kinase
Ga0080574_RS12055	COG0784	Response regulator, receiver
Ga0080574_RS12060	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Ga0080574_RS12065	COG5310	Homospermidine synthase
Ga0080574_RS12070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Ga0080574_RS12075	COG0287	Prephenate dehydrogenase
Ga0080574_RS12090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Ga0080574_RS12095	COG0165	Argininosuccinate lyase
Ga0080574_RS12120	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Ga0080574_RS12140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Ga0080574_RS12145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Ga0080574_RS12150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Ga0080574_RS12160	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Ga0080574_RS12170	COG0793	Belongs to the peptidase S41A family
Ga0080574_RS12175	COG1051	belongs to the nudix hydrolase family
Ga0080574_RS12185	COG2951	lytic endotransglycosylase activity
Ga0080574_RS12190	COG0557	exoribonuclease II activity
Ga0080574_RS12195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Ga0080574_RS12200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080574_RS12225	COG2171	N-acyltransferase activity
Ga0080574_RS12230	COG0840	transmembrane signaling receptor activity
Ga0080574_RS12235	COG0779	Required for maturation of 30S ribosomal subunits
Ga0080574_RS12250	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Ga0080574_RS12255	COG0494	nUDIX hydrolase
Ga0080574_RS12260	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Ga0080574_RS12265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Ga0080574_RS12270	COG0653	protein targeting
Ga0080574_RS12280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Ga0080574_RS12285	COG2003	Belongs to the UPF0758 family
Ga0080574_RS12295	COG0443	Heat shock 70 kDa protein
Ga0080574_RS12330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Ga0080574_RS12330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Ga0080574_RS12340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Ga0080574_RS12345	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Ga0080574_RS12350	COG2169	Transcriptional regulator
Ga0080574_RS12350	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Ga0080574_RS12355	COG2885	chlorophyll binding
Ga0080574_RS12365	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Ga0080574_RS12380	COG1137	ATPase activity
Ga0080574_RS12385	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Ga0080574_RS12390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Ga0080574_RS12420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Ga0080574_RS12425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Ga0080574_RS12460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Ga0080574_RS12470	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Ga0080574_RS12475	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Ga0080574_RS12480	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Ga0080574_RS12485	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Ga0080574_RS12490	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Ga0080574_RS12505	COG0840	transmembrane signaling receptor activity
Ga0080574_RS12525	COG1917	Cupin 2, conserved barrel domain protein
Ga0080574_RS12525	COG4977	sequence-specific DNA binding
Ga0080574_RS12530	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Ga0080574_RS12550	COG0540	Belongs to the ATCase OTCase family
Ga0080574_RS12555	COG1573	uracil-dna glycosylase
Ga0080574_RS12560	COG0521	Mo-molybdopterin cofactor biosynthetic process
Ga0080574_RS12570	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Ga0080574_RS12580	COG1678	Uncharacterized ACR, COG1678
Ga0080574_RS12585	COG0009	L-threonylcarbamoyladenylate synthase
Ga0080574_RS12590	COG1960	acyl-CoA dehydrogenase activity
Ga0080574_RS12620	COG0746	molybdenum cofactor guanylyltransferase activity
Ga0080574_RS12625	COG1763	Mo-molybdopterin cofactor biosynthetic process
Ga0080574_RS12635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Ga0080574_RS12655	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Ga0080574_RS12660	COG1473	amidohydrolase
Ga0080574_RS12665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Ga0080574_RS12675	COG3842	ATPase activity
Ga0080574_RS12680	COG0395	ABC-type sugar transport system, permease component
Ga0080574_RS12685	COG1176	ABC-type spermidine putrescine transport system, permease component I
Ga0080574_RS12695	COG1609	Transcriptional regulator
Ga0080574_RS12700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Ga0080574_RS12705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Ga0080574_RS12710	COG1845	cytochrome c oxidase, subunit III
Ga0080574_RS12715	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Ga0080574_RS12735	COG0446	pyridine nucleotide-disulphide oxidoreductase
Ga0080574_RS12735	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Ga0080574_RS12740	COG4311	Sarcosine oxidase, delta subunit
Ga0080574_RS12745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080574_RS12750	COG4977	sequence-specific DNA binding
Ga0080574_RS12760	COG1309	transcriptional regulator
Ga0080574_RS12765	COG1116	anion transmembrane transporter activity
Ga0080574_RS12765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ga0080574_RS12770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ga0080574_RS12775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ga0080574_RS12790	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
Ga0080574_RS12885	COG1132	(ABC) transporter
Ga0080574_RS12895	COG2826	transposase and inactivated derivatives, IS30 family
Ga0080574_RS12905	COG2132	Multicopper oxidase
Ga0080574_RS12935	COG2963	transposase activity
Ga0080574_RS12945	COG3328	transposase activity
Ga0080574_RS12960	COG1522	sequence-specific DNA binding
Ga0080574_RS12970	COG0747	negative chemotaxis
Ga0080574_RS12980	COG0444	Belongs to the ABC transporter superfamily
Ga0080574_RS12990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080574_RS13005	COG2072	flavoprotein involved in K transport
Ga0080574_RS13055	COG1176	ABC-type spermidine putrescine transport system, permease component I
Ga0080574_RS13060	COG1176	ABC-type spermidine putrescine transport system, permease component I
Ga0080574_RS13090	COG0583	DNA-binding transcription factor activity
Ga0080574_RS13095	COG0277	FAD linked oxidase domain protein
Ga0080574_RS13100	COG3273	potassium ion transport
Ga0080574_RS13100	COG0471	metal ion transport
Ga0080574_RS13105	COG2963	transposase activity
Ga0080574_RS13140	COG2433	Pfam Transposase IS66
Ga0080574_RS13145	COG3436	PFAM IS66 Orf2 family protein
Ga0080574_RS13190	COG5002	protein histidine kinase activity
Ga0080574_RS13200	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Ga0080574_RS13235	COG3328	transposase activity
Ga0080574_RS13260	COG2801	Transposase and inactivated derivatives
Ga0080574_RS13275	COG1203	CRISPR-associated helicase, Cas3
Ga0080574_RS13290	COG1857	crispr-associated protein
Ga0080574_RS13305	COG1518	maintenance of DNA repeat elements
Ga0080574_RS13310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Ga0080574_RS13315	COG3328	transposase activity
Ga0080574_RS13320	COG3328	transposase activity
Ga0080574_RS13350	COG0825	malonyl-CoA metabolic process
Ga0080574_RS13370	COG4067	protein conserved in archaea
Ga0080574_RS13370	COG0189	ligase activity
Ga0080574_RS13380	COG2823	Periplasmic or secreted lipoprotein
Ga0080574_RS13380	COG1652	LysM domain
Ga0080574_RS13385	COG2301	Belongs to the HpcH HpaI aldolase family
Ga0080574_RS13395	COG4948	Mandelate Racemase Muconate Lactonizing
Ga0080574_RS13415	COG1403	HNH endonuclease
Ga0080574_RS13420	COG0798	PFAM Bile acid sodium symporter
Ga0080574_RS13425	COG0438	transferase activity, transferring glycosyl groups
Ga0080574_RS13430	COG0254	rRNA binding
Ga0080574_RS13435	COG0335	large ribosomal subunit rRNA binding
Ga0080574_RS13455	COG0336	Belongs to the RNA methyltransferase TrmD family
Ga0080574_RS13465	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Ga0080574_RS13475	COG0228	four-way junction DNA binding
Ga0080574_RS13490	COG0519	Catalyzes the synthesis of GMP from XMP
Ga0080574_RS13510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Ga0080574_RS13540	COG0356	it plays a direct role in the translocation of protons across the membrane
Ga0080574_RS13545	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Ga0080574_RS13550	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Ga0080574_RS13555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Ga0080574_RS13560	COG0489	protein tyrosine kinase activity
Ga0080574_RS13560	COG2151	metal-sulfur cluster biosynthetic enzyme
Ga0080574_RS13590	COG0402	S-adenosylhomocysteine deaminase activity
Ga0080574_RS13595	COG1079	Belongs to the binding-protein-dependent transport system permease family
Ga0080574_RS13600	COG4603	Belongs to the binding-protein-dependent transport system permease family
Ga0080574_RS13605	COG3845	ABC transporter
Ga0080574_RS13630	COG2897	thiosulfate sulfurtransferase activity
Ga0080574_RS13635	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Ga0080574_RS13640	COG0513	Belongs to the DEAD box helicase family
Ga0080574_RS13645	COG2351	hydroxyisourate hydrolase activity
Ga0080574_RS13655	COG4266	Belongs to the allantoicase family
Ga0080574_RS13660	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
Ga0080574_RS13690	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Ga0080574_RS13695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Ga0080574_RS13700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Ga0080574_RS13715	COG0583	DNA-binding transcription factor activity
Ga0080574_RS13760	COG1058	Belongs to the CinA family
Ga0080574_RS13760	COG1546	Belongs to the CinA family
Ga0080574_RS13765	COG1489	DNA binding
Ga0080574_RS13770	COG0668	transmembrane transport
Ga0080574_RS13775	COG0024	Methionine aminopeptidase
Ga0080574_RS13785	COG0742	ribosomal rna small subunit methyltransferase
Ga0080574_RS13795	COG0678	peroxiredoxin activity
Ga0080574_RS13805	COG2853	Lipoprotein
Ga0080574_RS13810	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
Ga0080574_RS13815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ga0080574_RS13835	COG2154	pterin-4-alpha-carbinolamine dehydratase
Ga0080574_RS13845	COG0523	cobalamin synthesis protein
Ga0080574_RS13855	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Ga0080574_RS13860	COG0142	geranyltranstransferase activity
Ga0080574_RS13880	COG0583	DNA-binding transcription factor activity
Ga0080574_RS13885	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080574_RS13895	COG2200	EAL domain
Ga0080574_RS13900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Ga0080574_RS13905	COG0493	'glutamate synthase
Ga0080574_RS13920	COG1309	transcriptional regulator
Ga0080574_RS13950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ga0080574_RS13955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ga0080574_RS13970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Ga0080574_RS13975	COG1609	Transcriptional regulator
Ga0080574_RS14120	COG0305	Participates in initiation and elongation during chromosome replication
Ga0080574_RS14225	COG3617	BRO family, N-terminal domain
Ga0080574_RS14330	COG2951	lytic endotransglycosylase activity
Ga0080574_RS14340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Ga0080574_RS14350	COG0242	peptide deformylase activity
Ga0080574_RS14360	COG0242	peptide deformylase activity
Ga0080574_RS14365	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Ga0080574_RS14370	COG2860	membrane
Ga0080574_RS14375	COG0328	RNA-DNA hybrid ribonuclease activity
Ga0080574_RS14380	COG4106	trans-aconitate 2-methyltransferase activity
Ga0080574_RS14395	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Ga0080574_RS14420	COG0747	negative chemotaxis
Ga0080574_RS14425	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Ga0080574_RS14430	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Ga0080574_RS14445	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
Ga0080574_RS14460	COG0560	Phosphoserine phosphatase
Ga0080574_RS14480	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Ga0080574_RS14490	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
Ga0080574_RS14510	COG0514	ATP-dependent DNA helicase (RecQ)
Ga0080574_RS14515	COG3022	response to hydroperoxide
Ga0080574_RS14520	COG2205	protein histidine kinase activity
Ga0080574_RS14520	COG0784	Response regulator, receiver
Ga0080574_RS14520	COG5002	protein histidine kinase activity
Ga0080574_RS14525	COG2373	Large extracellular alpha-helical protein
Ga0080574_RS14535	COG4953	penicillin-binding protein 1C
Ga0080574_RS14540	COG0183	Belongs to the thiolase family
Ga0080574_RS14545	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Ga0080574_RS14545	COG3264	Mechanosensitive ion channel
Ga0080574_RS14550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Ga0080574_RS14555	COG0066	3-isopropylmalate dehydratase activity
Ga0080574_RS14565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Ga0080574_RS14585	COG1283	sodium-dependent phosphate transmembrane transporter activity
Ga0080574_RS14590	COG0697	spore germination
Ga0080574_RS14605	COG2801	Transposase and inactivated derivatives
Ga0080574_RS14615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080574_RS14625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Ga0080574_RS14630	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Ga0080574_RS14660	COG0642	Histidine kinase
Ga0080574_RS14670	COG3773	Cell wall hydrolase
Ga0080574_RS14675	COG1309	transcriptional regulator
Ga0080574_RS14690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ga0080574_RS14695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Ga0080574_RS14715	COG1968	undecaprenyl-diphosphatase activity
Ga0080574_RS14720	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Ga0080574_RS14725	COG0799	negative regulation of ribosome biogenesis
Ga0080574_RS14730	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080574_RS14740	COG0347	Belongs to the P(II) protein family
Ga0080574_RS14745	COG0004	ammonium transporteR
Ga0080574_RS14755	COG0314	molybdopterin synthase activity
Ga0080574_RS14765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Ga0080574_RS14770	COG1381	Involved in DNA repair and RecF pathway recombination
Ga0080574_RS14780	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Ga0080574_RS14790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Ga0080574_RS14805	COG1201	RNA secondary structure unwinding
Ga0080574_RS14810	COG0517	IMP dehydrogenase activity
Ga0080574_RS14830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Ga0080574_RS14835	COG0625	glutathione transferase activity
Ga0080574_RS14840	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Ga0080574_RS14845	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Ga0080574_RS14850	COG3454	Phosphonate metabolism
Ga0080574_RS14860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080574_RS14865	COG4172	Belongs to the ABC transporter superfamily
Ga0080574_RS14870	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080574_RS14890	COG1573	uracil-dna glycosylase
Ga0080574_RS14930	COG0501	Belongs to the peptidase M48B family
Ga0080574_RS14940	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Ga0080574_RS14950	COG0300	oxidoreductase activity
Ga0080574_RS14960	COG2096	Adenosyltransferase
Ga0080574_RS14965	COG0736	holo-[acyl-carrier-protein] synthase activity
Ga0080574_RS14970	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Ga0080574_RS14995	COG0596	Alpha beta hydrolase
Ga0080574_RS15000	COG3246	L-lysine catabolic process to acetate
Ga0080574_RS15005	COG4988	ABC transporter
Ga0080574_RS15010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Ga0080574_RS15015	COG1271	oxidase subunit
Ga0080574_RS15020	COG1294	oxidase, subunit
Ga0080574_RS15080	COG1132	(ABC) transporter
Ga0080574_RS15085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ga0080574_RS15095	COG0842	Transport permease protein
Ga0080574_RS15105	COG0456	acetyltransferase
Ga0080574_RS15125	COG1435	thymidine kinase activity
Ga0080574_RS15130	COG1183	phosphatidylcholine synthase activity
Ga0080574_RS15135	COG2808	Putative FMN-binding domain
Ga0080574_RS15140	COG3896	Chloramphenicol phosphotransferase-like protein
Ga0080574_RS15145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Ga0080574_RS15150	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Ga0080574_RS15200	COG0577	efflux transmembrane transporter activity
Ga0080574_RS15200	COG1136	(ABC) transporter
Ga0080574_RS15210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Ga0080574_RS15215	COG3383	formate dehydrogenase (NAD+) activity
Ga0080574_RS15230	COG0583	DNA-binding transcription factor activity
Ga0080574_RS15235	COG2111	Na H antiporter
Ga0080574_RS15235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Ga0080574_RS15240	COG1006	Multisubunit Na H antiporter MnhC subunit
Ga0080574_RS15245	COG0651	ATP synthesis coupled electron transport
Ga0080574_RS15255	COG2212	antiporter activity
Ga0080574_RS15260	COG1320	monovalent cation:proton antiporter activity
Ga0080574_RS15275	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Ga0080574_RS15280	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Ga0080574_RS15290	COG0706	membrane insertase activity
Ga0080574_RS15295	COG5001	Diguanylate cyclase
Ga0080574_RS15300	COG0037	tRNA processing
Ga0080574_RS15305	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Ga0080574_RS15310	COG0594	ribonuclease P activity
Ga0080574_RS15315	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Ga0080574_RS15330	COG4191	Histidine kinase
Ga0080574_RS15355	COG1376	ErfK ybiS ycfS ynhG family protein
Ga0080574_RS15360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Ga0080574_RS15360	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Ga0080574_RS15390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Ga0080574_RS15400	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Ga0080574_RS15410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Ga0080574_RS15430	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ga0080574_RS15440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Ga0080574_RS15455	COG2205	protein histidine kinase activity
Ga0080574_RS15460	COG0745	RESPONSE REGULATOR receiver
Ga0080574_RS15465	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Ga0080574_RS15485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Ga0080574_RS15495	COG1490	D-aminoacyl-tRNA deacylase activity
Ga0080574_RS15505	COG0071	Belongs to the small heat shock protein (HSP20) family
Ga0080574_RS15535	COG3853	Toxic anion resistance protein (TelA)
Ga0080574_RS15555	COG1187	pseudouridine synthase activity
Ga0080574_RS15560	COG0590	tRNA wobble adenosine to inosine editing
Ga0080574_RS15580	COG0708	Exodeoxyribonuclease III
Ga0080574_RS15585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Ga0080574_RS15600	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Ga0080574_RS15605	COG2835	tetraacyldisaccharide 4'-kinase activity
Ga0080574_RS15625	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Ga0080574_RS15640	COG1185	polyribonucleotide nucleotidyltransferase activity
Ga0080574_RS15650	COG0745	RESPONSE REGULATOR receiver
Ga0080574_RS15675	COG0006	proline dipeptidase activity
Ga0080574_RS15680	COG3842	ATPase activity
Ga0080574_RS15700	COG0840	transmembrane signaling receptor activity
Ga0080574_RS15750	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080574_RS15760	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Ga0080574_RS15765	COG0142	geranyltranstransferase activity
Ga0080574_RS15770	COG1722	exodeoxyribonuclease VII activity
Ga0080574_RS15775	COG0123	including yeast histone deacetylase and acetoin utilization protein
Ga0080574_RS15780	COG0745	RESPONSE REGULATOR receiver
Ga0080574_RS15785	COG1846	Transcriptional regulator
Ga0080574_RS15790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Ga0080574_RS15795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Ga0080574_RS15815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Ga0080574_RS15825	COG2884	Cell division ATP-binding protein ftsE
Ga0080574_RS15865	COG0508	dehydrogenase complex catalyzes the overall conversion of
Ga0080574_RS15870	COG0567	Dehydrogenase, E1 component
Ga0080574_RS15885	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Ga0080574_RS15895	COG0045	succinate-CoA ligase (ADP-forming) activity
Ga0080574_RS15905	COG0039	L-malate dehydrogenase activity
Ga0080574_RS15930	COG2030	dehydratase
Ga0080574_RS16035	COG0813	purine-nucleoside phosphorylase activity
Ga0080574_RS16045	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Ga0080574_RS16045	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Ga0080574_RS16050	COG0604	alcohol dehydrogenase
Ga0080574_RS16080	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Ga0080574_RS16085	COG1970	mechanosensitive ion channel activity
Ga0080574_RS16090	COG0625	glutathione transferase activity
Ga0080574_RS16120	COG0768	penicillin binding
Ga0080574_RS16125	COG0772	Belongs to the SEDS family
Ga0080574_RS16130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Ga0080574_RS16135	COG0686	Belongs to the AlaDH PNT family
Ga0080574_RS16165	COG0348	domain, Protein
Ga0080574_RS16170	COG0583	DNA-binding transcription factor activity
Ga0080574_RS16175	COG2010	Cytochrome c
Ga0080574_RS16200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Ga0080574_RS16205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Ga0080574_RS16210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Ga0080574_RS16215	COG1846	Transcriptional regulator
Ga0080574_RS16220	COG0697	spore germination
Ga0080574_RS16225	COG4172	Belongs to the ABC transporter superfamily
Ga0080574_RS16230	COG4239	(ABC) transporter, permease
Ga0080574_RS16235	COG4174	ABC transporter (Permease)
Ga0080574_RS16240	COG4166	transmembrane transport
Ga0080574_RS16275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Ga0080574_RS16290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Ga0080574_RS16305	COG0432	Pfam Uncharacterised protein family UPF0047
Ga0080574_RS16310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Ga0080574_RS16315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Ga0080574_RS16315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Ga0080574_RS16340	COG0039	L-malate dehydrogenase activity
Ga0080574_RS16345	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Ga0080574_RS16350	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Ga0080574_RS16355	COG0124	histidyl-tRNA synthetase
Ga0080574_RS16380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Ga0080574_RS16390	COG3845	ABC transporter
Ga0080574_RS16395	COG4603	Belongs to the binding-protein-dependent transport system permease family
Ga0080574_RS16400	COG1079	Belongs to the binding-protein-dependent transport system permease family
Ga0080574_RS16425	COG2801	Transposase and inactivated derivatives
Ga0080574_RS16435	COG0210	DNA helicase
Ga0080574_RS16470	COG0543	2 iron, 2 sulfur cluster binding
Ga0080574_RS16475	COG1802	Transcriptional regulator
Ga0080574_RS16480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080574_RS16485	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Ga0080574_RS16490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Ga0080574_RS16490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080574_RS16495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080574_RS16520	COG0778	Nitroreductase
Ga0080574_RS16540	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Ga0080574_RS16575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ga0080574_RS16585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ga0080574_RS16600	COG2186	Transcriptional regulator
Ga0080574_RS16605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Ga0080574_RS16610	COG0583	DNA-binding transcription factor activity
Ga0080574_RS16640	COG3350	monooxygenase activity
Ga0080574_RS16660	COG1063	alcohol dehydrogenase
Ga0080574_RS16675	COG0459	protein refolding
Ga0080574_RS16690	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080574_RS16695	COG1715	Restriction endonuclease
Ga0080574_RS16770	COG2307	Protein conserved in bacteria
Ga0080574_RS16770	COG2308	Evidence 4 Homologs of previously reported genes of
Ga0080574_RS16780	COG0583	DNA-binding transcription factor activity
Ga0080574_RS16790	COG0670	Belongs to the BI1 family
Ga0080574_RS16800	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Ga0080574_RS16800	COG0512	Glutamine amidotransferase of anthranilate synthase
Ga0080574_RS16810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Ga0080574_RS16840	COG1175	transmembrane transport
Ga0080574_RS16855	COG1720	tRNA m6t6A37 methyltransferase activity
Ga0080574_RS16860	COG0829	nickel cation binding
Ga0080574_RS16865	COG0831	urea catabolic process
Ga0080574_RS16875	COG0832	Belongs to the urease beta subunit family
Ga0080574_RS16900	COG0804	urea catabolic process
Ga0080574_RS16915	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Ga0080574_RS16925	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Ga0080574_RS16930	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Ga0080574_RS16975	COG0483	inositol monophosphate 1-phosphatase activity
Ga0080574_RS16995	COG1522	sequence-specific DNA binding
Ga0080574_RS17015	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Ga0080574_RS17100	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Ga0080574_RS17270	COG3179	chitinase
Ga0080574_RS17325	COG0131	Imidazoleglycerol-phosphate dehydratase
Ga0080574_RS17340	COG1648	precorrin-2 dehydrogenase activity
Ga0080574_RS17340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Ga0080574_RS17360	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Ga0080574_RS17370	COG3768	UPF0283 membrane protein
Ga0080574_RS17380	COG3106	COG3106 Predicted ATPase
Ga0080574_RS17390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080574_RS17390	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Ga0080574_RS17400	COG2030	dehydratase
Ga0080574_RS17415	COG1522	sequence-specific DNA binding
Ga0080574_RS17420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Ga0080574_RS17425	COG2423	ornithine cyclodeaminase activity
Ga0080574_RS17440	COG0729	surface antigen
Ga0080574_RS17460	COG2321	neutral zinc metallopeptidase
Ga0080574_RS17475	COG0737	Belongs to the 5'-nucleotidase family
Ga0080574_RS17480	COG2816	NAD+ diphosphatase activity
Ga0080574_RS17490	COG4136	ATPase activity
Ga0080574_RS17495	COG4135	transport system, permease component
Ga0080574_RS17500	COG4134	Bacterial extracellular solute-binding protein
Ga0080574_RS17505	COG4106	trans-aconitate 2-methyltransferase activity
Ga0080574_RS17535	COG4451	ribulose bisphosphate carboxylase, small
Ga0080574_RS17540	COG1850	ribulose-bisphosphate carboxylase activity
Ga0080574_RS17550	COG0126	phosphoglycerate kinase activity
Ga0080574_RS17570	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Ga0080574_RS17580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080574_RS17590	COG0577	efflux transmembrane transporter activity
Ga0080574_RS17590	COG1136	(ABC) transporter
Ga0080574_RS17595	COG1136	(ABC) transporter
Ga0080574_RS17595	COG0577	efflux transmembrane transporter activity
Ga0080574_RS17615	COG3436	PFAM IS66 Orf2 family protein
Ga0080574_RS17620	COG2433	Pfam Transposase IS66
Ga0080574_RS17625	COG2801	Transposase and inactivated derivatives
Ga0080574_RS17645	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Ga0080574_RS17680	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Ga0080574_RS17700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Ga0080574_RS17710	COG3001	Fructosamine kinase
Ga0080574_RS17720	COG1132	(ABC) transporter
Ga0080574_RS17730	COG3328	transposase activity
Ga0080574_RS17735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Ga0080574_RS17745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Ga0080574_RS17760	COG1136	(ABC) transporter
Ga0080574_RS17775	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080574_RS17795	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080574_RS17800	COG1172	Belongs to the binding-protein-dependent transport system permease family
Ga0080574_RS17810	COG1129	ABC transporter
Ga0080574_RS17850	COG1943	Transposase
Ga0080574_RS17855	COG0556	nucleotide-excision repair
Ga0080574_RS17865	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Ga0080574_RS17870	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Ga0080574_RS17875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Ga0080574_RS17895	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Ga0080574_RS17900	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Ga0080574_RS17915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Ga0080574_RS17920	COG0308	aminopeptidase N
Ga0080574_RS17935	COG3454	Phosphonate metabolism
Ga0080574_RS17940	COG2188	Transcriptional regulator
Ga0080574_RS17945	COG3624	Phosphonate C-P lyase system protein PhnG
Ga0080574_RS17955	COG3626	phosphonate metabolism
Ga0080574_RS17960	COG2852	Protein conserved in bacteria
Ga0080574_RS17965	COG3627	carbon phosphorus lyase activity
Ga0080574_RS17970	COG4107	phosphonate C-P lyase system protein PhnK
Ga0080574_RS17975	COG4778	phosphonate C-P lyase system protein PhnL
Ga0080574_RS17985	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Ga0080574_RS17990	COG3454	Phosphonate metabolism
Ga0080574_RS18020	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Ga0080574_RS18040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Ga0080574_RS18060	COG1793	dna ligase
Ga0080574_RS18080	COG0457	Tetratricopeptide repeat
Ga0080574_RS18095	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Ga0080574_RS18100	COG1329	Transcriptional regulator
Ga0080574_RS18105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Ga0080574_RS18105	COG0475	glutathione-regulated potassium exporter activity
Ga0080574_RS18135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Ga0080574_RS18140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Ga0080574_RS18145	COG0741	lytic transglycosylase activity
Ga0080574_RS18160	COG5265	(ABC) transporter
Ga0080574_RS18165	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Ga0080574_RS18175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Ga0080574_RS18205	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080574_RS18210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Ga0080574_RS18225	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080574_RS18235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Ga0080574_RS18250	COG4221	oxidoreductase activity
Ga0080574_RS18265	COG0601	transmembrane transport
Ga0080574_RS18270	COG0747	negative chemotaxis
Ga0080574_RS18310	COG4608	Belongs to the ABC transporter superfamily
Ga0080574_RS18320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080574_RS18355	COG3627	carbon phosphorus lyase activity
Ga0080574_RS18360	COG4107	phosphonate C-P lyase system protein PhnK
Ga0080574_RS18365	COG4778	phosphonate C-P lyase system protein PhnL
Ga0080574_RS18370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Ga0080574_RS18380	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Ga0080574_RS18400	COG3238	Protein conserved in bacteria
Ga0080574_RS18425	COG2358	TRAP transporter, solute receptor (TAXI family
Ga0080574_RS18430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Ga0080574_RS18440	COG2176	DNA-directed DNA polymerase activity
Ga0080574_RS18440	COG5002	protein histidine kinase activity
Ga0080574_RS18455	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Ga0080574_RS18465	COG0563	adenylate kinase activity
Ga0080574_RS18470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Ga0080574_RS18505	COG0784	Response regulator, receiver
Ga0080574_RS18525	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Ga0080574_RS18540	COG3487	Iron-regulated protein
Ga0080574_RS18595	COG0163	prenyltransferase activity
Ga0080574_RS18605	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Ga0080574_RS18615	COG2358	TRAP transporter, solute receptor (TAXI family
Ga0080574_RS18630	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080574_RS18655	COG1024	Enoyl-CoA hydratase
Ga0080574_RS18670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Ga0080574_RS18725	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Ga0080574_RS18775	COG1780	Probably involved in ribonucleotide reductase function
Ga0080574_RS18780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Ga0080574_RS18785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Ga0080574_RS18790	COG0583	DNA-binding transcription factor activity
Ga0080574_RS18795	COG1176	ABC-type spermidine putrescine transport system, permease component I
Ga0080574_RS18810	COG3842	ATPase activity
Ga0080574_RS18815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Ga0080574_RS18820	COG3246	L-lysine catabolic process to acetate
Ga0080574_RS18835	COG1024	Enoyl-CoA hydratase
Ga0080574_RS18835	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ga0080574_RS18840	COG0183	Belongs to the thiolase family
Ga0080574_RS18845	COG0625	glutathione transferase activity
Ga0080574_RS18855	COG1960	acyl-CoA dehydrogenase activity
Ga0080574_RS18890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Ga0080574_RS18915	COG0159	tryptophan synthase activity
Ga0080574_RS18940	COG0534	Mate efflux family protein
Ga0080574_RS18945	COG0012	GTP binding
Ga0080574_RS18950	COG0277	FAD linked oxidase domain protein
Ga0080574_RS19080	COG4387	Mu-like prophage protein GP36
Ga0080574_RS19090	COG4397	Mu-like prophage major head subunit gpT
Ga0080574_RS19225	COG2801	Transposase and inactivated derivatives
Ga0080574_RS19310	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Ga0080574_RS19315	COG0667	Aldo Keto reductase
Ga0080574_RS19320	COG2207	Transcriptional regulator
Ga0080574_RS19375	COG1349	DNA-binding transcription factor activity
Ga0080574_RS19380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Ga0080574_RS19395	COG1335	isochorismatase
Ga0080574_RS19440	COG0546	phosphoglycolate phosphatase activity
Ga0080574_RS19505	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Ga0080574_RS19535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Ga0080574_RS19540	COG0840	transmembrane signaling receptor activity
Ga0080574_RS19560	COG3293	Transposase
Ga0080574_RS19575	COG1994	Peptidase M50
Ga0080574_RS19575	COG0517	IMP dehydrogenase activity
Ga0080574_RS19610	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Ga0080574_RS19625	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080574_RS19630	COG4335	DNA alkylation repair
Ga0080574_RS19635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Ga0080574_RS19655	COG1160	GTP binding
Ga0080574_RS19670	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Ga0080574_RS19685	COG1862	Preprotein translocase
Ga0080574_RS19690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Ga0080574_RS19695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Ga0080574_RS19705	COG3737	Protein of unknown function (DUF498/DUF598)
Ga0080574_RS19710	COG4133	protoheme IX ABC transporter activity
Ga0080574_RS19715	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Ga0080574_RS19720	COG0569	domain protein
Ga0080574_RS19725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Ga0080574_RS19730	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Ga0080574_RS19740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Ga0080574_RS19745	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Ga0080574_RS19750	COG0126	phosphoglycerate kinase activity
Ga0080574_RS19770	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Ga0080574_RS19775	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Ga0080574_RS19780	COG0488	(ABC) transporter
Ga0080574_RS19790	COG0123	including yeast histone deacetylase and acetoin utilization protein
Ga0080574_RS19810	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Ga0080574_RS19820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Ga0080574_RS19825	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Ga0080574_RS19835	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Ga0080574_RS19855	COG0175	sulfate reduction
Ga0080574_RS19860	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Ga0080574_RS19870	COG1648	precorrin-2 dehydrogenase activity
Ga0080574_RS19870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Ga0080574_RS19875	COG1522	sequence-specific DNA binding
Ga0080574_RS19905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Ga0080574_RS19910	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Ga0080574_RS19915	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080574_RS19925	COG0149	triose-phosphate isomerase activity
Ga0080574_RS19930	COG0316	Belongs to the HesB IscA family
Ga0080574_RS19945	COG2151	metal-sulfur cluster biosynthetic enzyme
Ga0080574_RS19970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Ga0080574_RS19975	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Ga0080574_RS19980	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Ga0080574_RS20020	COG1612	heme a metabolic process
Ga0080574_RS20025	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Ga0080574_RS20040	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Ga0080574_RS20060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Ga0080574_RS20065	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Ga0080574_RS20075	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Ga0080574_RS20115	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Ga0080574_RS20125	COG3842	ATPase activity
Ga0080574_RS20135	COG1177	transmembrane transport
Ga0080574_RS20150	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Ga0080574_RS20155	COG1741	Belongs to the pirin family
Ga0080574_RS20170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Ga0080574_RS20180	COG0166	Belongs to the GPI family
Ga0080574_RS20210	COG3088	subunit of a heme lyase
Ga0080574_RS20220	COG1024	Enoyl-CoA hydratase
Ga0080574_RS20225	COG2814	Major facilitator Superfamily
Ga0080574_RS20245	COG0482	sulfurtransferase activity
Ga0080574_RS20260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Ga0080574_RS20280	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Ga0080574_RS20290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Ga0080574_RS20300	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Ga0080574_RS20310	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Ga0080574_RS20320	COG3909	cytochrome
Ga0080574_RS20325	COG2010	Cytochrome c
Ga0080574_RS20330	COG1546	Belongs to the CinA family
Ga0080574_RS20340	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Ga0080574_RS20340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Ga0080574_RS20345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Ga0080574_RS20350	COG3852	Histidine kinase
Ga0080574_RS20355	COG2204	response regulator
Ga0080574_RS20360	COG5000	phosphorelay sensor kinase activity
Ga0080574_RS20365	COG2204	response regulator
Ga0080574_RS20375	COG1923	regulation of RNA biosynthetic process
Ga0080574_RS20380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Ga0080574_RS20395	COG2084	Dehydrogenase
Ga0080574_RS20410	COG1764	response to oxidative stress
Ga0080574_RS20415	COG1530	ribonuclease E activity
Ga0080574_RS20420	COG0425	Belongs to the sulfur carrier protein TusA family
Ga0080574_RS20425	COG0785	Cytochrome C biogenesis protein
Ga0080574_RS20435	COG2124	cytochrome p450
Ga0080574_RS20440	COG3588	fructose-bisphosphate aldolase
Ga0080574_RS20460	COG0538	isocitrate dehydrogenase activity
Ga0080574_RS20465	COG2814	Major facilitator Superfamily
Ga0080574_RS20470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Ga0080574_RS20475	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Ga0080574_RS20490	COG1024	Enoyl-CoA hydratase
Ga0080574_RS20490	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ga0080574_RS20495	COG1960	acyl-CoA dehydrogenase activity
Ga0080574_RS20500	COG0438	transferase activity, transferring glycosyl groups
Ga0080574_RS20505	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Ga0080574_RS20525	COG0583	DNA-binding transcription factor activity
Ga0080574_RS20530	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Ga0080574_RS20535	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Ga0080574_RS20550	COG2161	toxin-antitoxin pair type II binding
Ga0080574_RS20555	COG4115	mRNA cleavage
Ga0080574_RS20565	COG0343	queuine tRNA-ribosyltransferase activity
Ga0080574_RS20570	COG1902	pentaerythritol trinitrate reductase activity
Ga0080574_RS20585	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Ga0080574_RS20590	COG4191	Histidine kinase
Ga0080574_RS20595	COG4566	intracellular signal transduction
Ga0080574_RS20620	COG2801	Transposase and inactivated derivatives
Ga0080574_RS20640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ga0080574_RS20645	COG1129	ABC transporter
Ga0080574_RS20645	COG0842	Transport permease protein
Ga0080574_RS20650	COG0842	Transport permease protein
Ga0080574_RS20660	COG0277	FAD linked oxidase domain protein
Ga0080574_RS20670	COG2095	MarC family integral membrane protein
Ga0080574_RS20675	COG0488	(ABC) transporter
Ga0080574_RS20680	COG0105	UTP biosynthetic process
Ga0080574_RS20745	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Ga0080574_RS20750	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080574_RS20760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Ga0080574_RS20775	COG0604	alcohol dehydrogenase
Ga0080574_RS20785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Ga0080574_RS20800	COG0415	Belongs to the DNA photolyase family
Ga0080574_RS20810	COG0494	nUDIX hydrolase
Ga0080574_RS20820	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Ga0080574_RS20820	COG3264	Mechanosensitive ion channel
Ga0080574_RS20825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Ga0080574_RS20830	COG1217	gtp-binding protein TYPA
Ga0080574_RS20840	COG0840	transmembrane signaling receptor activity
Ga0080574_RS20850	COG0018	arginyl-trna synthetase
Ga0080574_RS20860	COG1472	Belongs to the glycosyl hydrolase 3 family
Ga0080574_RS20865	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Ga0080574_RS20870	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Ga0080574_RS20885	COG0717	Belongs to the dCTP deaminase family
Ga0080574_RS20900	COG0776	regulation of translation
Ga0080574_RS20905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Ga0080574_RS20910	COG0416	fatty acid biosynthetic process
Ga0080574_RS20915	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Ga0080574_RS20970	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Ga0080574_RS21010	COG4536	flavin adenine dinucleotide binding
Ga0080574_RS21015	COG4974	Belongs to the 'phage' integrase family
Ga0080574_RS21025	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Ga0080574_RS21030	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Ga0080574_RS21045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Ga0080574_RS21060	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Ga0080574_RS21065	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Ga0080574_RS21070	COG0047	phosphoribosylformylglycinamidine synthase activity
Ga0080574_RS21080	COG2204	response regulator
Ga0080574_RS21100	COG0544	peptidyl-prolyl cis-trans isomerase activity
Ga0080574_RS21105	COG0359	binds to the 23S rRNA
Ga0080574_RS21110	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Ga0080574_RS21115	COG0360	Binds together with S18 to 16S ribosomal RNA
Ga0080574_RS21125	COG2353	YceI-like domain
Ga0080574_RS21130	COG2378	regulation of single-species biofilm formation
Ga0080574_RS21135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Ga0080574_RS21140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Ga0080574_RS21145	COG0805	protein transport
Ga0080574_RS21165	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Ga0080574_RS21170	COG4221	oxidoreductase activity
Ga0080574_RS21185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Ga0080574_RS21215	COG1127	ABC transporter
Ga0080574_RS21220	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Ga0080574_RS21225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Ga0080574_RS21235	COG0305	Participates in initiation and elongation during chromosome replication
Ga0080574_RS21240	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Ga0080574_RS21245	COG0418	dihydroorotase activity
Ga0080574_RS21255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Ga0080574_RS21265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Ga0080574_RS21270	COG1840	ABC-type Fe3 transport system, periplasmic component
Ga0080574_RS21275	COG3956	TIGRFAM MazG family protein
Ga0080574_RS21280	COG1473	amidohydrolase
Ga0080574_RS21285	COG1473	amidohydrolase
Ga0080574_RS21290	COG0010	Belongs to the arginase family
Ga0080574_RS21300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Ga0080574_RS21305	COG2890	protein-(glutamine-N5) methyltransferase activity
Ga0080574_RS21315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Ga0080574_RS21320	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Ga0080574_RS21330	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Ga0080574_RS21345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Ga0080574_RS21425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080574_RS21430	COG0601	transmembrane transport
Ga0080574_RS21440	COG4172	Belongs to the ABC transporter superfamily
Ga0080574_RS21445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080574_RS21450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080574_RS21455	COG1473	amidohydrolase
Ga0080574_RS21460	COG3909	cytochrome
Ga0080574_RS21480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Ga0080574_RS21485	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Ga0080574_RS21495	COG0215	cysteine-tRNA ligase activity
Ga0080574_RS21500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Ga0080574_RS21515	COG0372	Belongs to the citrate synthase family
Ga0080574_RS21520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Ga0080574_RS21525	COG2333	competence protein COMEC
Ga0080574_RS21525	COG0658	competence protein
Ga0080574_RS21530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Ga0080574_RS21535	COG0303	'Molybdopterin
Ga0080574_RS21540	COG0315	cyclic pyranopterin monophosphate synthase activity
Ga0080574_RS21545	COG0134	indole-3-glycerol-phosphate synthase activity
Ga0080574_RS21550	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Ga0080574_RS21555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Ga0080574_RS21575	COG5012	cobalamin binding
Ga0080574_RS21590	COG0646	methionine synthase
Ga0080574_RS21590	COG1410	methionine synthase
Ga0080574_RS21600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Ga0080574_RS21605	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Ga0080574_RS21620	COG0248	Ppx GppA phosphatase
Ga0080574_RS21625	COG0629	single-stranded DNA binding
Ga0080574_RS21630	COG0739	heme binding
Ga0080574_RS21630	COG0741	lytic transglycosylase activity
Ga0080574_RS21630	COG1196	nuclear chromosome segregation
Ga0080574_RS21635	COG1858	cytochrome C peroxidase
Ga0080574_RS21655	COG0528	UMP kinase activity
Ga0080574_RS21660	COG0233	cytoplasmic translational termination
Ga0080574_RS21665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Ga0080574_RS21675	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Ga0080574_RS21680	COG0750	zinc metalloprotease
Ga0080574_RS21695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Ga0080574_RS21700	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Ga0080574_RS21710	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Ga0080574_RS21735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Ga0080574_RS21750	COG1733	regulation of RNA biosynthetic process
Ga0080574_RS21755	COG0702	epimerase
Ga0080574_RS21760	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Ga0080574_RS21765	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Ga0080574_RS21770	COG0259	pyridoxamine-phosphate oxidase activity
Ga0080574_RS21775	COG1278	Cold shock
Ga0080574_RS21790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Ga0080574_RS21855	COG2133	pyrroloquinoline quinone binding
Ga0080574_RS21865	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Ga0080574_RS21875	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Ga0080574_RS21885	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Ga0080574_RS21900	COG1561	YicC-like family, N-terminal region
Ga0080574_RS21905	COG0194	GDP metabolic process
Ga0080574_RS21935	COG0573	inorganic phosphate transmembrane transporter activity
Ga0080574_RS21945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Ga0080574_RS21950	COG0704	Plays a role in the regulation of phosphate uptake
Ga0080574_RS21955	COG0745	RESPONSE REGULATOR receiver
Ga0080574_RS21965	COG0052	Belongs to the universal ribosomal protein uS2 family
Ga0080574_RS21970	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Ga0080574_RS21980	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Ga0080574_RS22000	COG2313	pseudouridylate synthase activity
Ga0080574_RS22025	COG3811	Belongs to the UPF0386 family
Ga0080574_RS22035	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080574_RS22040	COG4166	transmembrane transport
Ga0080574_RS22060	COG5002	protein histidine kinase activity
Ga0080574_RS22065	COG0433	COG0433 Predicted ATPase
Ga0080574_RS22080	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Ga0080574_RS22100	COG5425	PFAM Usg family protein
Ga0080574_RS22105	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Ga0080574_RS22125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Ga0080574_RS22135	COG3220	belongs to the UPF0276 family
Ga0080574_RS22150	COG1393	Belongs to the ArsC family
Ga0080574_RS22155	COG1278	Cold shock
Ga0080574_RS22160	COG0583	DNA-binding transcription factor activity
Ga0080574_RS22165	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Ga0080574_RS22175	COG1215	transferase activity, transferring glycosyl groups
Ga0080574_RS22180	COG0800	Aldolase
Ga0080574_RS22220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Ga0080574_RS22220	COG0519	Catalyzes the synthesis of GMP from XMP
Ga0080574_RS22230	COG0697	spore germination
Ga0080574_RS22250	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Ga0080574_RS22260	COG2326	polyphosphate kinase activity
Ga0080574_RS22265	COG1309	transcriptional regulator
Ga0080574_RS22280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Ga0080574_RS22285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Ga0080574_RS22300	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Ga0080574_RS22315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Ga0080574_RS22320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Ga0080574_RS22325	COG3842	ATPase activity
Ga0080574_RS22330	COG0366	Alpha amylase catalytic
Ga0080574_RS22335	COG0395	ABC-type sugar transport system, permease component
Ga0080574_RS22340	COG1175	transmembrane transport
Ga0080574_RS22345	COG1653	transport
Ga0080574_RS22350	COG1609	Transcriptional regulator
Ga0080574_RS22355	COG2723	6-phospho-beta-galactosidase activity
Ga0080574_RS22365	COG0058	SHG alpha-glucan phosphorylase activity
Ga0080574_RS22370	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Ga0080574_RS22375	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Ga0080574_RS22380	COG0297	glycogen (starch) synthase activity
Ga0080574_RS22395	COG0033	Phosphoglucomutase
Ga0080574_RS22425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Ga0080574_RS22435	COG2354	Protein conserved in bacteria
Ga0080574_RS22445	COG0431	NADPH-dependent FMN reductase
Ga0080574_RS22460	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Ga0080574_RS22470	COG3108	Peptidase M15
Ga0080574_RS22480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Ga0080574_RS22485	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Ga0080574_RS22485	COG3743	rRNA binding
Ga0080574_RS22505	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Ga0080574_RS22510	COG1653	transport
Ga0080574_RS22515	COG0395	ABC-type sugar transport system, permease component
Ga0080574_RS22520	COG1175	transmembrane transport
Ga0080574_RS22525	COG3842	ATPase activity
Ga0080574_RS22530	COG0583	DNA-binding transcription factor activity
Ga0080574_RS22535	COG2166	iron-sulfur cluster assembly
Ga0080574_RS22545	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Ga0080574_RS22555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Ga0080574_RS22560	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Ga0080574_RS22585	COG3963	phosphatidate phosphatase activity
Ga0080574_RS22590	COG0114	fumarate hydratase activity
Ga0080574_RS22610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Ga0080574_RS22630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Ga0080574_RS22635	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Ga0080574_RS22660	COG0010	Belongs to the arginase family
Ga0080574_RS22675	COG1238	metal cluster binding
Ga0080574_RS22710	COG0513	Belongs to the DEAD box helicase family
Ga0080574_RS22715	COG3842	ATPase activity
Ga0080574_RS22720	COG1177	transmembrane transport
Ga0080574_RS22750	COG2072	flavoprotein involved in K transport
Ga0080574_RS22765	COG1522	sequence-specific DNA binding
Ga0080574_RS22785	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Ga0080574_RS22795	COG3008	intermembrane lipid transfer
Ga0080574_RS22795	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Ga0080574_RS22800	COG2995	paraquat-inducible protein a
Ga0080574_RS22810	COG1063	alcohol dehydrogenase
Ga0080574_RS22815	COG0156	8-amino-7-oxononanoate synthase activity
Ga0080574_RS22830	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Ga0080574_RS22840	COG1007	ATP synthesis coupled electron transport
Ga0080574_RS22855	COG0713	ATP synthesis coupled electron transport
Ga0080574_RS22880	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Ga0080574_RS22945	COG0649	NAD binding
Ga0080574_RS22950	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Ga0080574_RS22955	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Ga0080574_RS22970	COG1024	Enoyl-CoA hydratase
Ga0080574_RS22980	COG0625	glutathione transferase activity
Ga0080574_RS22995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Ga0080574_RS23000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Ga0080574_RS23010	COG1960	acyl-CoA dehydrogenase activity
Ga0080574_RS23025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Ga0080574_RS23045	COG3842	ATPase activity
Ga0080574_RS23065	COG0129	dihydroxy-acid dehydratase activity
Ga0080574_RS23070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080574_RS23080	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Ga0080574_RS23100	COG0028	Belongs to the TPP enzyme family
Ga0080574_RS23105	COG0457	Tetratricopeptide repeat
Ga0080574_RS23145	COG0346	lactoylglutathione lyase activity
Ga0080574_RS23150	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Ga0080574_RS23155	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Ga0080574_RS23160	COG0860	N-Acetylmuramoyl-L-alanine amidase
Ga0080574_RS23165	COG0436	Aminotransferase
Ga0080574_RS23175	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Ga0080574_RS23175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Ga0080574_RS23185	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Ga0080574_RS23195	COG0156	8-amino-7-oxononanoate synthase activity
Ga0080574_RS23205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080574_RS23295	COG1846	Transcriptional regulator
Ga0080574_RS23305	COG0596	Alpha beta hydrolase
Ga0080574_RS23310	COG0583	DNA-binding transcription factor activity
Ga0080574_RS23325	COG0481	GTPase activity
Ga0080574_RS23350	COG0187	DNA topoisomerase II activity
Ga0080574_RS23400	COG1846	Transcriptional regulator
Ga0080574_RS23405	COG0456	acetyltransferase
Ga0080574_RS23410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Ga0080574_RS23415	COG1917	Cupin 2, conserved barrel domain protein
Ga0080574_RS23420	COG0527	aspartate kinase activity
Ga0080574_RS23435	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Ga0080574_RS23450	COG2917	probably involved in intracellular septation
Ga0080574_RS23460	COG1238	metal cluster binding
Ga0080574_RS23470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Ga0080574_RS23475	COG1758	RNA polymerase activity
Ga0080574_RS23480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Ga0080574_RS23495	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Ga0080574_RS23510	COG1570	exodeoxyribonuclease VII activity
Ga0080574_RS23515	COG0151	Belongs to the GarS family
Ga0080574_RS23525	COG0783	Belongs to the Dps family
Ga0080574_RS23535	COG2239	Acts as a magnesium transporter
Ga0080574_RS23540	COG0402	S-adenosylhomocysteine deaminase activity
Ga0080574_RS23560	COG0483	inositol monophosphate 1-phosphatase activity
Ga0080574_RS23565	COG1396	sequence-specific DNA binding
Ga0080574_RS23575	COG2267	carboxylic ester hydrolase activity
Ga0080574_RS23595	COG0217	transcriptional regulatory protein
Ga0080574_RS23600	COG0519	Catalyzes the synthesis of GMP from XMP
Ga0080574_RS23600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Ga0080574_RS23605	COG3273	potassium ion transport
Ga0080574_RS23605	COG0471	metal ion transport
Ga0080574_RS23610	COG1692	metallophosphoesterase
Ga0080574_RS23630	COG2124	cytochrome p450
Ga0080574_RS23640	COG0004	ammonium transporteR
Ga0080574_RS23650	COG0330	HflC and HflK could
Ga0080574_RS23655	COG0330	HflC and HflK could
Ga0080574_RS23665	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Ga0080574_RS23685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Ga0080574_RS23690	COG0508	dehydrogenase complex catalyzes the overall conversion of
Ga0080574_RS23690	COG0022	dehydrogenase e1 component
Ga0080574_RS23700	COG0508	dehydrogenase complex catalyzes the overall conversion of
Ga0080574_RS23705	COG2814	Major facilitator Superfamily
Ga0080574_RS23710	COG1045	serine acetyltransferase
Ga0080574_RS23790	COG4695	Portal protein
Ga0080574_RS23810	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Ga0080574_RS23835	COG0612	Peptidase, M16
Ga0080574_RS23840	COG0612	Peptidase, M16
Ga0080574_RS23850	COG0138	bifunctional purine biosynthesis protein purh
Ga0080574_RS23860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Ga0080574_RS23860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Ga0080574_RS23875	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Ga0080574_RS23880	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Ga0080574_RS23885	COG3698	Phosphodiester glycosidase
Ga0080574_RS23890	COG0312	modulator of DNA gyrase
Ga0080574_RS23905	COG1519	Transferase
Ga0080574_RS23910	COG1663	tetraacyldisaccharide 4'-kinase activity
Ga0080574_RS23925	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Ga0080574_RS23935	COG0135	phosphoribosylanthranilate isomerase activity
Ga0080574_RS23945	COG0776	regulation of translation
Ga0080574_RS23950	COG0539	negative regulation of cytoplasmic translation
Ga0080574_RS23955	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Ga0080574_RS23960	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Ga0080574_RS23965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Ga0080574_RS23980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Ga0080574_RS23985	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Ga0080574_RS24000	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Ga0080574_RS24010	COG1703	isobutyryl-CoA mutase activity
Ga0080574_RS24015	COG1643	Atp-dependent helicase
Ga0080574_RS24020	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Ga0080574_RS24025	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Ga0080574_RS24030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Ga0080574_RS24040	COG0101	tRNA pseudouridine synthase activity
Ga0080574_RS24050	COG0306	phosphate transporter
Ga0080574_RS24065	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Ga0080574_RS24065	COG0446	pyridine nucleotide-disulphide oxidoreductase
Ga0080574_RS24090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080574_RS24095	COG4235	cytochrome complex assembly
Ga0080574_RS24100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Ga0080574_RS24110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Ga0080574_RS24135	COG0071	Belongs to the small heat shock protein (HSP20) family
Ga0080574_RS24150	COG0438	transferase activity, transferring glycosyl groups
Ga0080574_RS24165	COG0542	response to heat
Ga0080574_RS24175	COG0501	Belongs to the peptidase M48B family
Ga0080574_RS24185	COG0071	Belongs to the small heat shock protein (HSP20) family
Ga0080574_RS24190	COG0071	Belongs to the small heat shock protein (HSP20) family
Ga0080574_RS24195	COG0583	DNA-binding transcription factor activity
Ga0080574_RS24205	COG2948	multi-organism process
Ga0080574_RS24220	COG3846	protein secretion by the type IV secretion system
Ga0080574_RS24255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Ga0080574_RS24270	COG0542	response to heat
Ga0080574_RS24490	COG1431	PFAM Stem cell self-renewal protein Piwi
Ga0080574_RS24540	COG0542	response to heat
Ga0080574_RS24835	COG1104	cysteine desulfurase activity
Ga0080574_RS25275	COG0741	lytic transglycosylase activity