locus-tag	class	description
CDM120_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDM120_RS00010	COG0592	DNA-directed DNA polymerase activity
CDM120_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDM120_RS00025	COG0187	DNA topoisomerase II activity
CDM120_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDM120_RS00045	COG1366	Belongs to the anti-sigma-factor antagonist family
CDM120_RS00055	COG1191	sigma factor activity
CDM120_RS00105	COG1827	regulation of RNA biosynthetic process
CDM120_RS00110	COG0668	transmembrane transport
CDM120_RS00115	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDM120_RS00120	COG0590	tRNA wobble adenosine to inosine editing
CDM120_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDM120_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDM120_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDM120_RS00150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDM120_RS00390	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CDM120_RS00395	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDM120_RS00400	COG4463	regulation of RNA biosynthetic process
CDM120_RS00405	COG3880	PFAM UvrB UvrC protein
CDM120_RS00410	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CDM120_RS00415	COG0542	response to heat
CDM120_RS00420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CDM120_RS00425	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CDM120_RS00430	COG4956	integral membrane protein (PIN domain superfamily)
CDM120_RS00450	COG3507	Belongs to the glycosyl hydrolase 43 family
CDM120_RS00460	COG2205	protein histidine kinase activity
CDM120_RS00465	COG0745	RESPONSE REGULATOR receiver
CDM120_RS00475	COG2390	Transcriptional regulator
CDM120_RS00480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDM120_RS00485	COG0022	dehydrogenase e1 component
CDM120_RS00490	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDM120_RS00495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDM120_RS00500	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDM120_RS00500	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDM120_RS00510	COG3414	Phosphotransferase system galactitol-specific IIB component
CDM120_RS00515	COG3775	system Galactitol-specific IIC component
CDM120_RS00530	COG0095	Lipoate-protein ligase
CDM120_RS00535	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CDM120_RS00540	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CDM120_RS00545	COG0442	prolyl-tRNA aminoacylation
CDM120_RS00550	COG0442	prolyl-tRNA aminoacylation
CDM120_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDM120_RS00565	COG0215	cysteine-tRNA ligase activity
CDM120_RS00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDM120_RS00585	COG3688	RNA-binding protein containing a PIN domain
CDM120_RS00595	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDM120_RS00600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDM120_RS00610	COG0250	Participates in transcription elongation, termination and antitermination
CDM120_RS00615	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDM120_RS00620	COG0081	regulation of translation
CDM120_RS00625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDM120_RS00630	COG0222	ribosome binding
CDM120_RS00640	COG0085	RNA polymerase activity
CDM120_RS00645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDM120_RS00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDM120_RS00655	COG0049	tRNA binding
CDM120_RS00660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDM120_RS00665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDM120_RS00670	COG0051	transcription antitermination factor activity, RNA binding
CDM120_RS00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDM120_RS00680	COG0088	Forms part of the polypeptide exit tunnel
CDM120_RS00685	COG0089	rRNA binding
CDM120_RS00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDM120_RS00695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDM120_RS00700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDM120_RS00705	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDM120_RS00710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDM120_RS00715	COG0255	Belongs to the universal ribosomal protein uL29 family
CDM120_RS00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDM120_RS00725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDM120_RS00730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CDM120_RS00735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDM120_RS00740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDM120_RS00745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDM120_RS00750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDM120_RS00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDM120_RS00760	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDM120_RS00765	COG1841	ribosomal large subunit assembly
CDM120_RS00770	COG0200	Binds to the 23S rRNA
CDM120_RS00780	COG0563	adenylate kinase activity
CDM120_RS00785	COG0024	Methionine aminopeptidase
CDM120_RS00795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDM120_RS00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDM120_RS00805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDM120_RS00810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDM120_RS00815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDM120_RS00820	COG0202	RNA polymerase activity
CDM120_RS00825	COG0203	ribosomal protein L17
CDM120_RS00830	COG1122	ATPase activity
CDM120_RS00835	COG1122	ATPase activity
CDM120_RS00840	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CDM120_RS00845	COG0101	tRNA pseudouridine synthase activity
CDM120_RS00850	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDM120_RS00855	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDM120_RS00860	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDM120_RS01075	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CDM120_RS01090	COG0280	phosphate acetyltransferase
CDM120_RS01125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDM120_RS01130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDM120_RS01135	COG2897	thiosulfate sulfurtransferase activity
CDM120_RS01145	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDM120_RS01150	COG2385	sporulation resulting in formation of a cellular spore
CDM120_RS01160	COG1609	Transcriptional regulator
CDM120_RS01165	COG1077	Cell shape determining protein MreB Mrl
CDM120_RS01170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDM120_RS01180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDM120_RS01185	COG3949	Membrane
CDM120_RS01190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDM120_RS01195	COG1040	competence protein
CDM120_RS01200	COG3711	transcriptional antiterminator
CDM120_RS01200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS01205	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDM120_RS01210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDM120_RS01215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDM120_RS01225	COG1446	asparaginase
CDM120_RS01230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDM120_RS01240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CDM120_RS01245	COG0653	protein targeting
CDM120_RS01250	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CDM120_RS01255	COG2183	response to ionizing radiation
CDM120_RS01260	COG1228	amidohydrolase
CDM120_RS01275	COG0802	atpase or kinase
CDM120_RS01280	COG1214	PFAM Peptidase M22, glycoprotease
CDM120_RS01285	COG0456	acetyltransferase
CDM120_RS01290	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDM120_RS01295	COG1882	Formate acetyltransferase
CDM120_RS01305	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CDM120_RS01345	COG0534	Mate efflux family protein
CDM120_RS01350	COG0488	(ABC) transporter
CDM120_RS01355	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CDM120_RS01365	COG2221	Nitrite and sulphite reductase 4Fe-4S
CDM120_RS01375	COG1151	hydroxylamine reductase activity
CDM120_RS01390	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDM120_RS01425	COG0540	Belongs to the ATCase OTCase family
CDM120_RS01430	COG0543	2 iron, 2 sulfur cluster binding
CDM120_RS01435	COG0167	dihydroorotate dehydrogenase activity
CDM120_RS01450	COG0583	DNA-binding transcription factor activity
CDM120_RS01465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDM120_RS01470	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDM120_RS01475	COG0459	protein refolding
CDM120_RS01480	COG1691	(AIR) carboxylase
CDM120_RS01485	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CDM120_RS01490	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CDM120_RS01495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDM120_RS01495	COG0519	Catalyzes the synthesis of GMP from XMP
CDM120_RS01550	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDM120_RS01555	COG2200	EAL domain
CDM120_RS01555	COG2771	luxR family
CDM120_RS01570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS01575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS01585	COG1011	Hydrolase
CDM120_RS01600	COG0778	Nitroreductase
CDM120_RS01605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CDM120_RS01610	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDM120_RS01615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CDM120_RS01620	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDM120_RS01625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDM120_RS01630	COG0138	bifunctional purine biosynthesis protein purh
CDM120_RS01635	COG0151	Belongs to the GarS family
CDM120_RS01640	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDM120_RS01650	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CDM120_RS01660	COG1088	dTDP-glucose 4,6-dehydratase activity
CDM120_RS01665	COG0741	lytic transglycosylase activity
CDM120_RS01700	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CDM120_RS01705	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CDM120_RS01720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CDM120_RS01730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDM120_RS01740	COG1215	transferase activity, transferring glycosyl groups
CDM120_RS01780	COG1454	alcohol dehydrogenase
CDM120_RS01785	COG1533	DNA photolyase activity
CDM120_RS01800	COG1733	regulation of RNA biosynthetic process
CDM120_RS01815	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDM120_RS01820	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDM120_RS01820	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDM120_RS01825	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDM120_RS01825	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDM120_RS01850	COG3716	PTS system mannose fructose sorbose family IID component
CDM120_RS01860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDM120_RS01875	COG1131	(ABC) transporter
CDM120_RS01895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDM120_RS01905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDM120_RS01910	COG1879	ABC-type sugar transport system periplasmic component
CDM120_RS01915	COG1129	ABC transporter
CDM120_RS01920	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDM120_RS01925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDM120_RS01935	COG1473	amidohydrolase
CDM120_RS01975	COG2217	Heavy metal translocating P-type atpase
CDM120_RS01995	COG0586	Pfam SNARE associated Golgi protein
CDM120_RS02015	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CDM120_RS02025	COG1122	ATPase activity
CDM120_RS02030	COG0210	DNA helicase
CDM120_RS02035	COG1362	aminopeptidase activity
CDM120_RS02045	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDM120_RS02060	COG1012	belongs to the aldehyde dehydrogenase family
CDM120_RS02060	COG1454	alcohol dehydrogenase
CDM120_RS02070	COG1136	(ABC) transporter
CDM120_RS02100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDM120_RS02105	COG2357	RelA SpoT domain protein
CDM120_RS02125	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CDM120_RS02150	COG2190	(PTS) system
CDM120_RS02150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS02150	COG1263	PTS System
CDM120_RS02155	COG2723	6-phospho-beta-galactosidase activity
CDM120_RS02160	COG3711	transcriptional antiterminator
CDM120_RS02170	COG0367	asparagine synthase
CDM120_RS02185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDM120_RS02210	COG1960	acyl-CoA dehydrogenase activity
CDM120_RS02215	COG2086	electron transfer activity
CDM120_RS02220	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDM120_RS02225	COG3829	transcription factor binding
CDM120_RS02230	COG0191	fructose-bisphosphate aldolase activity
CDM120_RS02240	COG1187	pseudouridine synthase activity
CDM120_RS02270	COG1401	restriction endodeoxyribonuclease activity
CDM120_RS02355	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDM120_RS02390	COG1802	Transcriptional regulator
CDM120_RS02390	COG4626	Terminase
CDM120_RS02480	COG4824	toxin secretion phage lysis holin
CDM120_RS02505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDM120_RS02520	COG2226	methyltransferase
CDM120_RS02530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDM120_RS02550	COG1484	DNA-dependent DNA replication
CDM120_RS02610	COG1484	DNA-dependent DNA replication
CDM120_RS02750	COG3843	relaxase mobilization nuclease domain protein
CDM120_RS02840	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDM120_RS02845	COG0745	RESPONSE REGULATOR receiver
CDM120_RS02860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDM120_RS02880	COG3254	rhamnose metabolic process
CDM120_RS02910	COG3829	transcription factor binding
CDM120_RS02915	COG3804	dihydrodipicolinate reductase
CDM120_RS02925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDM120_RS02935	COG5012	cobalamin binding
CDM120_RS02945	COG3457	Alanine racemase
CDM120_RS02950	COG1757	Na H antiporter
CDM120_RS02965	COG1051	belongs to the nudix hydrolase family
CDM120_RS02975	COG3973	AAA domain
CDM120_RS02985	COG1136	(ABC) transporter
CDM120_RS02995	COG5002	protein histidine kinase activity
CDM120_RS03000	COG0745	RESPONSE REGULATOR receiver
CDM120_RS03020	COG1131	(ABC) transporter
CDM120_RS03110	COG1595	DNA-templated transcription, initiation
CDM120_RS03190	COG0768	penicillin binding
CDM120_RS03215	COG1131	(ABC) transporter
CDM120_RS03230	COG0745	RESPONSE REGULATOR receiver
CDM120_RS03235	COG5002	protein histidine kinase activity
CDM120_RS03240	COG1136	(ABC) transporter
CDM120_RS03240	COG0577	efflux transmembrane transporter activity
CDM120_RS03245	COG1136	(ABC) transporter
CDM120_RS03250	COG5002	protein histidine kinase activity
CDM120_RS03255	COG0745	RESPONSE REGULATOR receiver
CDM120_RS03260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDM120_RS03275	COG1063	alcohol dehydrogenase
CDM120_RS03285	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS03295	COG3716	PTS system mannose fructose sorbose family IID component
CDM120_RS03305	COG5002	protein histidine kinase activity
CDM120_RS03315	COG1686	Belongs to the peptidase S11 family
CDM120_RS03320	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDM120_RS03320	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDM120_RS03340	COG2205	protein histidine kinase activity
CDM120_RS03365	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDM120_RS03370	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CDM120_RS03390	COG2378	regulation of single-species biofilm formation
CDM120_RS03400	COG2201	protein-glutamate methylesterase activity
CDM120_RS03405	COG1776	CheC inhibitor of MCP methylation
CDM120_RS03410	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CDM120_RS03415	COG0835	chemotaxis
CDM120_RS03425	COG0840	transmembrane signaling receptor activity
CDM120_RS03430	COG0643	Histidine kinase
CDM120_RS03430	COG2198	Histidine kinase
CDM120_RS03435	COG0835	chemotaxis
CDM120_RS03445	COG2201	protein-glutamate methylesterase activity
CDM120_RS03495	COG2339	peptidase activity
CDM120_RS03500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDM120_RS03500	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CDM120_RS03505	COG0681	Belongs to the peptidase S26 family
CDM120_RS03520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDM120_RS03525	COG2066	Belongs to the glutaminase family
CDM120_RS03535	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CDM120_RS03550	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDM120_RS03555	COG1067	ATP-dependent peptidase activity
CDM120_RS03560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDM120_RS03565	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDM120_RS03575	COG1744	ABC transporter substrate-binding protein PnrA-like
CDM120_RS03605	COG4399	Belongs to the UPF0754 family
CDM120_RS03605	COG4399	Belongs to the UPF0754 family
CDM120_RS03610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDM120_RS03655	COG1309	transcriptional regulator
CDM120_RS03660	COG0574	Belongs to the PEP-utilizing enzyme family
CDM120_RS03660	COG3848	Pyruvate phosphate dikinase
CDM120_RS03670	COG1716	ATPase activity
CDM120_RS03670	COG5001	Diguanylate cyclase
CDM120_RS03675	COG2199	diguanylate cyclase activity
CDM120_RS03720	COG3969	phosphoadenosine phosphosulfate
CDM120_RS03725	COG1475	DNA binding
CDM120_RS03740	COG3546	catalase activity
CDM120_RS03755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDM120_RS03770	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CDM120_RS03770	COG0456	acetyltransferase
CDM120_RS03805	COG0789	Transcriptional regulator
CDM120_RS03805	COG4978	Transcriptional regulator
CDM120_RS03850	COG0305	Participates in initiation and elongation during chromosome replication
CDM120_RS03870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDM120_RS03925	COG1131	(ABC) transporter
CDM120_RS03930	COG1802	Transcriptional regulator
CDM120_RS03935	COG0823	Involved in the tonB-independent uptake of proteins
CDM120_RS03935	COG4946	Tricorn protease homolog
CDM120_RS03935	COG1506	peptidase
CDM120_RS03940	COG1506	peptidase
CDM120_RS03940	COG4946	Tricorn protease homolog
CDM120_RS03940	COG0823	Involved in the tonB-independent uptake of proteins
CDM120_RS03950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDM120_RS03970	COG0038	chloride channel
CDM120_RS04050	COG0745	RESPONSE REGULATOR receiver
CDM120_RS04055	COG0745	RESPONSE REGULATOR receiver
CDM120_RS04055	COG3292	Two component regulator propeller
CDM120_RS04055	COG2205	protein histidine kinase activity
CDM120_RS04095	COG1595	DNA-templated transcription, initiation
CDM120_RS04105	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CDM120_RS04110	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CDM120_RS04115	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDM120_RS04155	COG0789	Transcriptional regulator
CDM120_RS04175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDM120_RS04180	COG0569	domain protein
CDM120_RS04185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDM120_RS04190	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDM120_RS04195	COG0072	phenylalanine-tRNA ligase activity
CDM120_RS04195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDM120_RS04215	COG0826	peptidase U32
CDM120_RS04225	COG1051	belongs to the nudix hydrolase family
CDM120_RS04235	COG3706	GGDEF domain
CDM120_RS04240	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDM120_RS04245	COG1193	negative regulation of DNA recombination
CDM120_RS04250	COG1683	Conserved Protein
CDM120_RS04255	COG0018	arginyl-trna synthetase
CDM120_RS04280	COG0583	DNA-binding transcription factor activity
CDM120_RS04285	COG0110	maltose O-acetyltransferase activity
CDM120_RS04290	COG0280	phosphate acetyltransferase
CDM120_RS04295	COG1151	hydroxylamine reductase activity
CDM120_RS04305	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CDM120_RS04310	COG3404	Formiminotransferase-cyclodeaminase
CDM120_RS04315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDM120_RS04325	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CDM120_RS04325	COG0646	methionine synthase
CDM120_RS04330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDM120_RS04360	COG0509	glycine decarboxylation via glycine cleavage system
CDM120_RS04380	COG0095	Lipoate-protein ligase
CDM120_RS04400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDM120_RS04415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDM120_RS04415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDM120_RS04430	COG1349	DNA-binding transcription factor activity
CDM120_RS04440	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDM120_RS04445	COG1360	Flagellar Motor Protein
CDM120_RS04465	COG0210	DNA helicase
CDM120_RS04470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDM120_RS04475	COG0765	amino acid transport
CDM120_RS04480	COG1126	abc transporter atp-binding protein
CDM120_RS04490	COG0301	tRNA thio-modification
CDM120_RS04500	COG0778	Nitroreductase
CDM120_RS04505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CDM120_RS04515	COG0530	calcium, potassium:sodium antiporter activity
CDM120_RS04520	COG0513	Belongs to the DEAD box helicase family
CDM120_RS04550	COG1028	Short-chain dehydrogenase reductase Sdr
CDM120_RS04555	COG0243	molybdopterin cofactor binding
CDM120_RS04560	COG1366	Belongs to the anti-sigma-factor antagonist family
CDM120_RS04565	COG2172	sigma factor antagonist activity
CDM120_RS04570	COG1191	sigma factor activity
CDM120_RS04580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDM120_RS04605	COG1473	amidohydrolase
CDM120_RS04615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDM120_RS04625	COG0750	zinc metalloprotease
CDM120_RS04630	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDM120_RS04635	COG0488	(ABC) transporter
CDM120_RS04650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDM120_RS04665	COG1739	Uncharacterized protein family UPF0029
CDM120_RS04675	COG0730	response to heat
CDM120_RS04680	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDM120_RS04685	COG0217	transcriptional regulatory protein
CDM120_RS04690	COG1024	Enoyl-CoA hydratase
CDM120_RS04695	COG2610	gluconate transmembrane transporter activity
CDM120_RS04710	COG2086	electron transfer activity
CDM120_RS04715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDM120_RS04760	COG2186	Transcriptional regulator
CDM120_RS04765	COG2814	Major facilitator Superfamily
CDM120_RS04770	COG1263	PTS System
CDM120_RS04770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS04770	COG2190	(PTS) system
CDM120_RS04775	COG2723	6-phospho-beta-galactosidase activity
CDM120_RS04785	COG0745	RESPONSE REGULATOR receiver
CDM120_RS04790	COG5002	protein histidine kinase activity
CDM120_RS04810	COG1592	Rubrerythrin
CDM120_RS04820	COG2033	superoxide reductase activity
CDM120_RS04825	COG0069	glutamate synthase activity
CDM120_RS04855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDM120_RS04865	COG0473	3-isopropylmalate dehydrogenase activity
CDM120_RS04870	COG1846	Transcriptional regulator
CDM120_RS04895	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDM120_RS04900	COG0138	bifunctional purine biosynthesis protein purh
CDM120_RS04910	COG0297	glycogen (starch) synthase activity
CDM120_RS04910	COG0438	transferase activity, transferring glycosyl groups
CDM120_RS04950	COG1473	amidohydrolase
CDM120_RS04965	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CDM120_RS04980	COG0601	transmembrane transport
CDM120_RS04985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDM120_RS04995	COG0444	Belongs to the ABC transporter superfamily
CDM120_RS05000	COG4608	Belongs to the ABC transporter superfamily
CDM120_RS05005	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDM120_RS05005	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDM120_RS05020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDM120_RS05030	COG1486	melibiose metabolic process
CDM120_RS05040	COG1073	alpha beta
CDM120_RS05050	COG1910	domain protein
CDM120_RS05055	COG0725	ABC transporter, periplasmic molybdate-binding protein
CDM120_RS05060	COG4149	molybdate abc transporter
CDM120_RS05065	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDM120_RS05070	COG0110	maltose O-acetyltransferase activity
CDM120_RS05085	COG4120	Belongs to the binding-protein-dependent transport system permease family
CDM120_RS05090	COG2984	ABC transporter substrate binding protein
CDM120_RS05100	COG4120	Belongs to the binding-protein-dependent transport system permease family
CDM120_RS05105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDM120_RS05105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDM120_RS05120	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDM120_RS05125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDM120_RS05130	COG0297	glycogen (starch) synthase activity
CDM120_RS05135	COG0058	SHG alpha-glucan phosphorylase activity
CDM120_RS05145	COG1802	Transcriptional regulator
CDM120_RS05150	COG1982	Orn Lys Arg decarboxylase major
CDM120_RS05155	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CDM120_RS05160	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CDM120_RS05165	COG0010	Belongs to the arginase family
CDM120_RS05200	COG4868	Belongs to the UPF0371 family
CDM120_RS05205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDM120_RS05215	COG1174	glycine betaine transport
CDM120_RS05220	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDM120_RS05250	COG0534	Mate efflux family protein
CDM120_RS05255	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDM120_RS05255	COG0539	negative regulation of cytoplasmic translation
CDM120_RS05260	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDM120_RS05270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDM120_RS05275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDM120_RS05280	COG0066	3-isopropylmalate dehydratase activity
CDM120_RS05285	COG0473	3-isopropylmalate dehydrogenase activity
CDM120_RS05300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDM120_RS05315	COG5002	protein histidine kinase activity
CDM120_RS05315	COG3447	MASE1 domain protein
CDM120_RS05315	COG5001	Diguanylate cyclase
CDM120_RS05340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDM120_RS05345	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CDM120_RS05355	COG0281	malic enzyme
CDM120_RS05370	COG0745	RESPONSE REGULATOR receiver
CDM120_RS05375	COG5002	protein histidine kinase activity
CDM120_RS05380	COG0577	efflux transmembrane transporter activity
CDM120_RS05380	COG1136	(ABC) transporter
CDM120_RS05400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDM120_RS05405	COG0363	glucosamine-6-phosphate deaminase activity
CDM120_RS05420	COG5002	protein histidine kinase activity
CDM120_RS05425	COG5001	Diguanylate cyclase
CDM120_RS05435	COG0789	Transcriptional regulator
CDM120_RS05435	COG4978	Transcriptional regulator
CDM120_RS05445	COG1132	(ABC) transporter
CDM120_RS05465	COG2364	Membrane
CDM120_RS05475	COG3842	ATPase activity
CDM120_RS05480	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDM120_RS05485	COG1177	transmembrane transport
CDM120_RS05490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CDM120_RS05500	COG5298	Protein conserved in bacteria
CDM120_RS05505	COG1215	transferase activity, transferring glycosyl groups
CDM120_RS05520	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CDM120_RS05550	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDM120_RS05550	COG2247	cell wall binding repeat
CDM120_RS05560	COG1074	ATP-dependent DNA helicase activity
CDM120_RS05570	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CDM120_RS05575	COG1074	ATP-dependent DNA helicase activity
CDM120_RS05580	COG0420	3'-5' exonuclease activity
CDM120_RS05585	COG0419	ATPase involved in DNA repair
CDM120_RS05590	COG4536	flavin adenine dinucleotide binding
CDM120_RS05600	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDM120_RS05610	COG0622	Phosphoesterase
CDM120_RS05615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDM120_RS05620	COG1131	(ABC) transporter
CDM120_RS05635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDM120_RS05640	COG1960	acyl-CoA dehydrogenase activity
CDM120_RS05645	COG2086	electron transfer activity
CDM120_RS05650	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDM120_RS05665	COG0183	Belongs to the thiolase family
CDM120_RS05670	COG0564	pseudouridine synthase activity
CDM120_RS05680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDM120_RS05730	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDM120_RS05735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDM120_RS05740	COG4224	UPF0291 protein
CDM120_RS05745	COG1362	aminopeptidase activity
CDM120_RS05750	COG2188	Transcriptional regulator
CDM120_RS05770	COG3715	PTS system
CDM120_RS05775	COG3716	PTS system mannose fructose sorbose family IID component
CDM120_RS05780	COG0583	DNA-binding transcription factor activity
CDM120_RS05800	COG3414	Phosphotransferase system galactitol-specific IIB component
CDM120_RS05805	COG1132	(ABC) transporter
CDM120_RS05815	COG1473	amidohydrolase
CDM120_RS05830	COG3279	Response regulator of the LytR AlgR family
CDM120_RS05845	COG1882	Formate acetyltransferase
CDM120_RS05850	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CDM120_RS05855	COG1396	sequence-specific DNA binding
CDM120_RS05880	COG3708	Transcriptional regulator
CDM120_RS05880	COG2207	Transcriptional regulator
CDM120_RS05915	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDM120_RS05915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDM120_RS05920	COG0237	dephospho-CoA kinase activity
CDM120_RS05945	COG0346	lactoylglutathione lyase activity
CDM120_RS05950	COG0791	NLP P60 protein
CDM120_RS05960	COG4656	Part of a membrane complex involved in electron transport
CDM120_RS05965	COG4658	electron transport chain
CDM120_RS05970	COG4659	FMN binding
CDM120_RS05975	COG4660	Part of a membrane complex involved in electron transport
CDM120_RS05980	COG4657	Part of a membrane complex involved in electron transport
CDM120_RS05985	COG2878	Part of a membrane complex involved in electron transport
CDM120_RS05985	COG1245	4Fe-4S binding domain
CDM120_RS05990	COG0424	maF-like protein
CDM120_RS05995	COG2003	Belongs to the UPF0758 family
CDM120_RS06000	COG1077	Cell shape determining protein MreB Mrl
CDM120_RS06020	COG0850	regulation of cytokinetic process
CDM120_RS06025	COG2894	cell division
CDM120_RS06030	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDM120_RS06035	COG0772	Belongs to the SEDS family
CDM120_RS06040	COG1803	Methylglyoxal synthase
CDM120_RS06045	COG1695	Transcriptional regulator
CDM120_RS06060	COG0426	domain, Protein
CDM120_RS06075	COG1530	ribonuclease E activity
CDM120_RS06080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDM120_RS06090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDM120_RS06095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDM120_RS06105	COG0460	homoserine dehydrogenase
CDM120_RS06115	COG3314	Sporulation integral membrane protein YlbJ
CDM120_RS06120	COG2186	Transcriptional regulator
CDM120_RS06125	COG3875	lactate racemase activity
CDM120_RS06130	COG2086	electron transfer activity
CDM120_RS06135	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDM120_RS06140	COG0277	FAD linked oxidase domain protein
CDM120_RS06145	COG1323	Belongs to the UPF0348 family
CDM120_RS06150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDM120_RS06160	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDM120_RS06170	COG0416	fatty acid biosynthetic process
CDM120_RS06175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDM120_RS06185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDM120_RS06190	COG1028	Short-chain dehydrogenase reductase Sdr
CDM120_RS06195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDM120_RS06200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDM120_RS06205	COG3706	GGDEF domain
CDM120_RS06220	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDM120_RS06235	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CDM120_RS06240	COG3854	ATPases associated with a variety of cellular activities
CDM120_RS06280	COG1302	Protein conserved in bacteria
CDM120_RS06285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDM120_RS06290	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDM120_RS06295	COG1570	exodeoxyribonuclease VII activity
CDM120_RS06300	COG1722	exodeoxyribonuclease VII activity
CDM120_RS06310	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CDM120_RS06315	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDM120_RS06320	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CDM120_RS06325	COG0497	DNA recombination
CDM120_RS06335	COG0456	acetyltransferase
CDM120_RS06340	COG0456	acetyltransferase
CDM120_RS06345	COG0750	zinc metalloprotease
CDM120_RS06380	COG0494	nUDIX hydrolase
CDM120_RS06390	COG4974	Belongs to the 'phage' integrase family
CDM120_RS06395	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CDM120_RS06410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDM120_RS06415	COG4122	O-methyltransferase activity
CDM120_RS06420	COG0826	peptidase U32
CDM120_RS06425	COG0768	penicillin binding
CDM120_RS06525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDM120_RS06535	COG0571	ribonuclease III activity
CDM120_RS06545	COG1196	nuclear chromosome segregation
CDM120_RS06550	COG0552	protein localization to endoplasmic reticulum
CDM120_RS06565	COG0228	four-way junction DNA binding
CDM120_RS06575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDM120_RS06580	COG0336	Belongs to the RNA methyltransferase TrmD family
CDM120_RS06585	COG0335	large ribosomal subunit rRNA binding
CDM120_RS06595	COG1114	Component of the transport system for branched-chain amino acids
CDM120_RS06610	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDM120_RS06640	COG1131	(ABC) transporter
CDM120_RS06645	COG2197	response regulator
CDM120_RS06650	COG4585	Histidine kinase
CDM120_RS06655	COG0792	nuclease activity
CDM120_RS06660	COG0606	chelatase, subunit chli
CDM120_RS06665	COG0758	DNA mediated transformation
CDM120_RS06670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDM120_RS06680	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDM120_RS06690	COG1959	2 iron, 2 sulfur cluster binding
CDM120_RS06700	COG0822	iron-sulfur transferase activity
CDM120_RS06705	COG0482	sulfurtransferase activity
CDM120_RS06710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDM120_RS06715	COG4472	Bacterial protein of unknown function (DUF965)
CDM120_RS06725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDM120_RS06730	COG3906	Belongs to the UPF0473 family
CDM120_RS06735	COG0735	belongs to the Fur family
CDM120_RS06745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CDM120_RS06755	COG1686	Belongs to the peptidase S11 family
CDM120_RS06765	COG2207	Transcriptional regulator
CDM120_RS06765	COG1917	Cupin 2, conserved barrel domain protein
CDM120_RS06770	COG1994	Peptidase M50
CDM120_RS06780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDM120_RS06835	COG0779	Required for maturation of 30S ribosomal subunits
CDM120_RS06840	COG0195	Participates in both transcription termination and antitermination
CDM120_RS06845	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CDM120_RS06855	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CDM120_RS06865	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CDM120_RS06870	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDM120_RS06875	COG0196	riboflavin kinase activity
CDM120_RS06885	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDM120_RS06890	COG1307	EDD domain protein, DegV family
CDM120_RS06895	COG1185	polyribonucleotide nucleotidyltransferase activity
CDM120_RS06905	COG0612	Peptidase, M16
CDM120_RS06910	COG1873	PFAM PRC-barrel domain
CDM120_RS06915	COG0527	aspartate kinase activity
CDM120_RS06920	COG0740	serine-type endopeptidase activity
CDM120_RS06930	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CDM120_RS06935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDM120_RS06945	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDM120_RS06950	COG1418	mRNA catabolic process
CDM120_RS06955	COG5001	Diguanylate cyclase
CDM120_RS06975	COG1968	undecaprenyl-diphosphatase activity
CDM120_RS06985	COG0114	fumarate hydratase activity
CDM120_RS06995	COG0436	Aminotransferase
CDM120_RS07005	COG0708	Exodeoxyribonuclease III
CDM120_RS07020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDM120_RS07045	COG1131	(ABC) transporter
CDM120_RS07075	COG1278	Cold shock
CDM120_RS07085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDM120_RS07165	COG3299	homolog of phage Mu protein gp47
CDM120_RS07170	COG3778	Protein conserved in bacteria
CDM120_RS07200	COG1396	sequence-specific DNA binding
CDM120_RS07215	COG1396	sequence-specific DNA binding
CDM120_RS07220	COG2814	Major facilitator Superfamily
CDM120_RS07230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDM120_RS07235	COG3273	potassium ion transport
CDM120_RS07235	COG0471	metal ion transport
CDM120_RS07240	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CDM120_RS07245	COG1914	H( )-stimulated, divalent metal cation uptake system
CDM120_RS07250	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CDM120_RS07255	COG1984	allophanate hydrolase subunit 2
CDM120_RS07260	COG1396	sequence-specific DNA binding
CDM120_RS07265	COG4948	Mandelate Racemase Muconate Lactonizing
CDM120_RS07310	COG1473	amidohydrolase
CDM120_RS07315	COG1619	proteins homologs of microcin C7 resistance protein MccF
CDM120_RS07330	COG0584	glycerophosphoryl diester phosphodiesterase
CDM120_RS07360	COG0488	(ABC) transporter
CDM120_RS07370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDM120_RS07375	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDM120_RS07380	COG1058	Belongs to the CinA family
CDM120_RS07380	COG1546	Belongs to the CinA family
CDM120_RS07395	COG3829	transcription factor binding
CDM120_RS07405	COG1242	4 iron, 4 sulfur cluster binding
CDM120_RS07430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CDM120_RS07435	COG3447	MASE1 domain protein
CDM120_RS07435	COG5001	Diguanylate cyclase
CDM120_RS07435	COG5002	protein histidine kinase activity
CDM120_RS07440	COG2199	diguanylate cyclase activity
CDM120_RS07440	COG2203	Gaf domain
CDM120_RS07450	COG4978	Transcriptional regulator
CDM120_RS07450	COG0789	Transcriptional regulator
CDM120_RS07460	COG1285	pathogenesis
CDM120_RS07475	COG0726	polysaccharide deacetylase
CDM120_RS07490	COG0450	alkyl hydroperoxide reductase
CDM120_RS07505	COG2720	vancomycin resistance protein
CDM120_RS07510	COG3829	transcription factor binding
CDM120_RS07525	COG1346	cytolysis
CDM120_RS07530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDM120_RS07540	COG2340	Cysteine-rich secretory protein family
CDM120_RS07545	COG0726	polysaccharide deacetylase
CDM120_RS07550	COG0512	Glutamine amidotransferase of anthranilate synthase
CDM120_RS07555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDM120_RS07560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDM120_RS07570	COG0302	gtp cyclohydrolase
CDM120_RS07575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDM120_RS07580	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDM120_RS07585	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDM120_RS07590	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CDM120_RS07595	COG0358	DNA primase activity
CDM120_RS07600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDM120_RS07605	COG2384	SAM-dependent methyltransferase
CDM120_RS07610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDM120_RS07615	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDM120_RS07635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDM120_RS07645	COG0745	RESPONSE REGULATOR receiver
CDM120_RS07650	COG3850	Histidine kinase
CDM120_RS07650	COG5002	protein histidine kinase activity
CDM120_RS07655	COG0577	efflux transmembrane transporter activity
CDM120_RS07655	COG1136	(ABC) transporter
CDM120_RS07685	COG1132	(ABC) transporter
CDM120_RS07690	COG1132	(ABC) transporter
CDM120_RS07695	COG1592	Rubrerythrin
CDM120_RS07695	COG1773	rubredoxin
CDM120_RS07735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDM120_RS07770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDM120_RS07775	COG2011	ABC-type metal ion transport system permease component
CDM120_RS07780	COG1464	Belongs to the NlpA lipoprotein family
CDM120_RS07785	COG5002	protein histidine kinase activity
CDM120_RS07790	COG2094	Belongs to the DNA glycosylase MPG family
CDM120_RS07795	COG1396	sequence-specific DNA binding
CDM120_RS07800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDM120_RS07805	COG4086	secreted protein
CDM120_RS07825	COG0803	Belongs to the bacterial solute-binding protein 9 family
CDM120_RS07830	COG1121	(ABC) transporter
CDM120_RS07835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDM120_RS07840	COG0523	cobalamin synthesis protein
CDM120_RS07845	COG0701	Predicted permease
CDM120_RS07860	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDM120_RS07870	COG1131	(ABC) transporter
CDM120_RS07880	COG0534	Mate efflux family protein
CDM120_RS07895	COG3901	Regulator of nitric oxide reductase transcription
CDM120_RS07895	COG0348	domain, Protein
CDM120_RS07920	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDM120_RS07925	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDM120_RS07935	COG5001	Diguanylate cyclase
CDM120_RS07940	COG0789	Transcriptional regulator
CDM120_RS07940	COG4978	Transcriptional regulator
CDM120_RS07945	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CDM120_RS07965	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDM120_RS07970	COG0726	polysaccharide deacetylase
CDM120_RS07980	COG1773	rubredoxin
CDM120_RS07980	COG1592	Rubrerythrin
CDM120_RS07985	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDM120_RS07990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDM120_RS07995	COG0577	efflux transmembrane transporter activity
CDM120_RS08000	COG1136	(ABC) transporter
CDM120_RS08000	COG0577	efflux transmembrane transporter activity
CDM120_RS08010	COG2205	protein histidine kinase activity
CDM120_RS08015	COG0745	RESPONSE REGULATOR receiver
CDM120_RS08020	COG1136	(ABC) transporter
CDM120_RS08025	COG0577	efflux transmembrane transporter activity
CDM120_RS08030	COG0405	Gamma-glutamyltransferase
CDM120_RS08045	COG0493	'glutamate synthase
CDM120_RS08045	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDM120_RS08055	COG1136	(ABC) transporter
CDM120_RS08060	COG0577	efflux transmembrane transporter activity
CDM120_RS08100	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CDM120_RS08105	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDM120_RS08110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDM120_RS08115	COG0131	Imidazoleglycerol-phosphate dehydratase
CDM120_RS08120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDM120_RS08125	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDM120_RS08130	COG0107	imidazoleglycerol-phosphate synthase activity
CDM120_RS08135	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDM120_RS08135	COG0140	phosphoribosyl-ATP diphosphatase activity
CDM120_RS08140	COG0531	amino acid
CDM120_RS08155	COG1595	DNA-templated transcription, initiation
CDM120_RS08170	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDM120_RS08185	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDM120_RS08190	COG0028	Belongs to the TPP enzyme family
CDM120_RS08195	COG3546	catalase activity
CDM120_RS08200	COG1331	Highly conserved protein containing a thioredoxin domain
CDM120_RS08210	COG2267	carboxylic ester hydrolase activity
CDM120_RS08215	COG1136	(ABC) transporter
CDM120_RS08235	COG3584	3D domain protein
CDM120_RS08235	COG1388	LysM domain
CDM120_RS08245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDM120_RS08250	COG1295	ribonuclease BN
CDM120_RS08255	COG5002	protein histidine kinase activity
CDM120_RS08260	COG0460	homoserine dehydrogenase
CDM120_RS08270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDM120_RS08275	COG0596	Alpha beta hydrolase
CDM120_RS08290	COG1940	carbohydrate kinase activity
CDM120_RS08295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDM120_RS08300	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CDM120_RS08305	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CDM120_RS08310	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CDM120_RS08315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDM120_RS08320	COG1045	serine acetyltransferase
CDM120_RS08330	COG0024	Methionine aminopeptidase
CDM120_RS08345	COG0351	phosphomethylpyrimidine kinase
CDM120_RS08350	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CDM120_RS08355	COG0352	thiamine-phosphate diphosphorylase activity
CDM120_RS08360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDM120_RS08380	COG1725	Transcriptional regulator
CDM120_RS08385	COG1131	(ABC) transporter
CDM120_RS08410	COG0402	S-adenosylhomocysteine deaminase activity
CDM120_RS08420	COG4555	ABC transporter
CDM120_RS08425	COG1668	transmembrane transport
CDM120_RS08430	COG3300	MHYT domain
CDM120_RS08430	COG5001	Diguanylate cyclase
CDM120_RS08435	COG1725	Transcriptional regulator
CDM120_RS08440	COG1131	(ABC) transporter
CDM120_RS08455	COG0668	transmembrane transport
CDM120_RS08465	COG0426	domain, Protein
CDM120_RS08485	COG0367	asparagine synthase
CDM120_RS08490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDM120_RS08505	COG2310	stress, protein
CDM120_RS08520	COG3853	Toxic anion resistance protein (TelA)
CDM120_RS08550	COG5505	Protein of unknown function (DUF819)
CDM120_RS08560	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDM120_RS08565	COG4605	iron ion homeostasis
CDM120_RS08570	COG4604	ABC transporter, ATP-binding protein
CDM120_RS08575	COG4607	ABC-type enterochelin transport system periplasmic component
CDM120_RS08595	COG0095	Lipoate-protein ligase
CDM120_RS08600	COG1757	Na H antiporter
CDM120_RS08610	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDM120_RS08615	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDM120_RS08620	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDM120_RS08625	COG3123	guanosine phosphorylase activity
CDM120_RS08650	COG1396	sequence-specific DNA binding
CDM120_RS08660	COG0584	glycerophosphoryl diester phosphodiesterase
CDM120_RS08675	COG1131	(ABC) transporter
CDM120_RS08685	COG0745	RESPONSE REGULATOR receiver
CDM120_RS08690	COG2205	protein histidine kinase activity
CDM120_RS08705	COG1733	regulation of RNA biosynthetic process
CDM120_RS08710	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CDM120_RS08740	COG1309	transcriptional regulator
CDM120_RS08775	COG0745	RESPONSE REGULATOR receiver
CDM120_RS08780	COG5002	protein histidine kinase activity
CDM120_RS08785	COG3118	belongs to the thioredoxin family
CDM120_RS08815	COG1115	amino acid carrier protein
CDM120_RS08830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDM120_RS08830	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDM120_RS08845	COG0514	ATP-dependent DNA helicase (RecQ)
CDM120_RS08850	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDM120_RS08865	COG2022	thiamine diphosphate biosynthetic process
CDM120_RS08880	COG1288	antiporter activity
CDM120_RS08900	COG0393	Putative heavy-metal-binding
CDM120_RS08905	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDM120_RS08915	COG0315	cyclic pyranopterin monophosphate synthase activity
CDM120_RS08985	COG1283	sodium-dependent phosphate transmembrane transporter activity
CDM120_RS08990	COG2207	Transcriptional regulator
CDM120_RS08995	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CDM120_RS09050	COG5012	cobalamin binding
CDM120_RS09055	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDM120_RS09065	COG1011	Hydrolase
CDM120_RS09070	COG1917	Cupin 2, conserved barrel domain protein
CDM120_RS09070	COG1396	sequence-specific DNA binding
CDM120_RS09075	COG2610	gluconate transmembrane transporter activity
CDM120_RS09080	COG5002	protein histidine kinase activity
CDM120_RS09085	COG2204	response regulator
CDM120_RS09100	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CDM120_RS09125	COG0786	glutamate:sodium symporter activity
CDM120_RS09150	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CDM120_RS09155	COG1924	4 iron, 4 sulfur cluster binding
CDM120_RS09170	COG1309	transcriptional regulator
CDM120_RS09195	COG0242	peptide deformylase activity
CDM120_RS09230	COG3326	Membrane
CDM120_RS09240	COG0494	nUDIX hydrolase
CDM120_RS09285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDM120_RS09290	COG0765	amino acid transport
CDM120_RS09300	COG1393	Belongs to the ArsC family
CDM120_RS09310	COG1606	tRNA processing
CDM120_RS09315	COG0116	Belongs to the methyltransferase superfamily
CDM120_RS09330	COG3850	Histidine kinase
CDM120_RS09330	COG5002	protein histidine kinase activity
CDM120_RS09340	COG0137	argininosuccinate synthase activity
CDM120_RS09350	COG0789	Transcriptional regulator
CDM120_RS09360	COG2323	membrane
CDM120_RS09375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDM120_RS09400	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDM120_RS09405	COG0583	DNA-binding transcription factor activity
CDM120_RS09420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDM120_RS09430	COG1609	Transcriptional regulator
CDM120_RS09440	COG1621	beta-fructofuranosidase activity
CDM120_RS09445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDM120_RS09455	COG2814	Major facilitator Superfamily
CDM120_RS09460	COG2814	Major facilitator Superfamily
CDM120_RS09490	COG0406	alpha-ribazole phosphatase activity
CDM120_RS09495	COG2081	HI0933 family
CDM120_RS09500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CDM120_RS09505	COG0204	Acyl-transferase
CDM120_RS09510	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDM120_RS09525	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDM120_RS09530	COG3022	response to hydroperoxide
CDM120_RS09545	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CDM120_RS09550	COG1846	Transcriptional regulator
CDM120_RS09555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDM120_RS09560	COG2205	protein histidine kinase activity
CDM120_RS09570	COG0598	Magnesium transport protein CorA
CDM120_RS09580	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CDM120_RS09585	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDM120_RS09590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDM120_RS09595	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDM120_RS09600	COG1605	Chorismate mutase
CDM120_RS09600	COG0077	Prephenate dehydratase
CDM120_RS09605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDM120_RS09615	COG0287	Prephenate dehydrogenase
CDM120_RS09625	COG5002	protein histidine kinase activity
CDM120_RS09625	COG5001	Diguanylate cyclase
CDM120_RS09645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDM120_RS09650	COG2226	methyltransferase
CDM120_RS09655	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
CDM120_RS09685	COG2131	deaminase
CDM120_RS09720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDM120_RS09725	COG0582	viral genome integration into host DNA
CDM120_RS09730	COG0582	viral genome integration into host DNA
CDM120_RS09735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDM120_RS09775	COG4819	ethanolamine utilization protein
CDM120_RS09780	COG4303	Ethanolamine ammonia lyase large subunit
CDM120_RS09785	COG4302	ethanolamine ammonia-lyase activity
CDM120_RS09800	COG1012	belongs to the aldehyde dehydrogenase family
CDM120_RS09800	COG1454	alcohol dehydrogenase
CDM120_RS09815	COG4869	propanediol catabolic process
CDM120_RS09825	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CDM120_RS09835	COG3192	ethanolamine utilization protein
CDM120_RS09840	COG4766	ethanolamine catabolic process
CDM120_RS09860	COG1116	anion transmembrane transporter activity
CDM120_RS09880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDM120_RS09885	COG4974	Belongs to the 'phage' integrase family
CDM120_RS09900	COG2359	stage V sporulation protein S
CDM120_RS09905	COG0825	malonyl-CoA metabolic process
CDM120_RS09910	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDM120_RS09915	COG0439	Biotin carboxylase
CDM120_RS09920	COG0511	ligase activity, forming carbon-carbon bonds
CDM120_RS09940	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDM120_RS09950	COG1136	(ABC) transporter
CDM120_RS09960	COG2205	protein histidine kinase activity
CDM120_RS09965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDM120_RS09970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDM120_RS09990	COG0577	efflux transmembrane transporter activity
CDM120_RS09990	COG1136	(ABC) transporter
CDM120_RS09995	COG2205	protein histidine kinase activity
CDM120_RS10000	COG0745	RESPONSE REGULATOR receiver
CDM120_RS10010	COG0745	RESPONSE REGULATOR receiver
CDM120_RS10015	COG5002	protein histidine kinase activity
CDM120_RS10020	COG0577	efflux transmembrane transporter activity
CDM120_RS10020	COG1136	(ABC) transporter
CDM120_RS10030	COG2264	protein methyltransferase activity
CDM120_RS10060	COG1811	Na channel or pump
CDM120_RS10065	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
CDM120_RS10080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDM120_RS10085	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CDM120_RS10090	COG1923	regulation of RNA biosynthetic process
CDM120_RS10095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDM120_RS10100	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDM120_RS10105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CDM120_RS10110	COG1116	anion transmembrane transporter activity
CDM120_RS10115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDM120_RS10120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDM120_RS10140	COG1733	regulation of RNA biosynthetic process
CDM120_RS10145	COG0384	phenazine biosynthesis protein PhzF
CDM120_RS10150	COG0494	nUDIX hydrolase
CDM120_RS10160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDM120_RS10165	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDM120_RS10165	COG2247	cell wall binding repeat
CDM120_RS10310	COG2207	Transcriptional regulator
CDM120_RS10315	COG1321	iron dependent repressor
CDM120_RS10320	COG0789	Transcriptional regulator
CDM120_RS10335	COG1404	Belongs to the peptidase S8 family
CDM120_RS10395	COG0741	lytic transglycosylase activity
CDM120_RS10395	COG0791	NLP P60 protein
CDM120_RS10425	COG2946	Replication initiation factor
CDM120_RS10435	COG1674	ftsk spoiiie
CDM120_RS10450	COG0129	dihydroxy-acid dehydratase activity
CDM120_RS10480	COG2207	Transcriptional regulator
CDM120_RS10485	COG2814	Major facilitator Superfamily
CDM120_RS10505	COG1725	Transcriptional regulator
CDM120_RS10530	COG1794	racemase activity, acting on amino acids and derivatives
CDM120_RS10540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDM120_RS10545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDM120_RS10550	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDM120_RS10555	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDM120_RS10565	COG0456	acetyltransferase
CDM120_RS10575	COG1309	transcriptional regulator
CDM120_RS10595	COG3655	Transcriptional regulator
CDM120_RS10615	COG1737	Transcriptional regulator
CDM120_RS10620	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CDM120_RS10625	COG1187	pseudouridine synthase activity
CDM120_RS10630	COG0628	permease
CDM120_RS10640	COG0019	diaminopimelate decarboxylase activity
CDM120_RS10645	COG0527	aspartate kinase activity
CDM120_RS10675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDM120_RS10680	COG1597	lipid kinase activity
CDM120_RS10710	COG0582	viral genome integration into host DNA
CDM120_RS10720	COG0488	(ABC) transporter
CDM120_RS10735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDM120_RS10745	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDM120_RS10745	COG2080	2 iron, 2 sulfur cluster binding
CDM120_RS10755	COG2233	PERMEase
CDM120_RS10765	COG0167	dihydroorotate dehydrogenase activity
CDM120_RS10770	COG0402	S-adenosylhomocysteine deaminase activity
CDM120_RS10790	COG0402	S-adenosylhomocysteine deaminase activity
CDM120_RS10815	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDM120_RS10840	COG3829	transcription factor binding
CDM120_RS10850	COG1401	restriction endodeoxyribonuclease activity
CDM120_RS10865	COG4708	membrane
CDM120_RS10875	COG2080	2 iron, 2 sulfur cluster binding
CDM120_RS10875	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDM120_RS10910	COG1131	(ABC) transporter
CDM120_RS10920	COG2252	PERMEase
CDM120_RS10925	COG0534	Mate efflux family protein
CDM120_RS10935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDM120_RS10940	COG1349	DNA-binding transcription factor activity
CDM120_RS10950	COG5002	protein histidine kinase activity
CDM120_RS10955	COG0745	RESPONSE REGULATOR receiver
CDM120_RS10960	COG2217	Heavy metal translocating P-type atpase
CDM120_RS10975	COG1217	gtp-binding protein TYPA
CDM120_RS10980	COG0492	ferredoxin-NADP+ reductase activity
CDM120_RS11020	COG1247	-acetyltransferase
CDM120_RS11040	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CDM120_RS11045	COG0750	zinc metalloprotease
CDM120_RS11050	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CDM120_RS11060	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CDM120_RS11065	COG1518	maintenance of DNA repeat elements
CDM120_RS11125	COG4589	Belongs to the CDS family
CDM120_RS11140	COG0233	cytoplasmic translational termination
CDM120_RS11145	COG0528	UMP kinase activity
CDM120_RS11150	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDM120_RS11155	COG0052	Belongs to the universal ribosomal protein uS2 family
CDM120_RS11160	COG1686	Belongs to the peptidase S11 family
CDM120_RS11180	COG1193	negative regulation of DNA recombination
CDM120_RS11195	COG2720	vancomycin resistance protein
CDM120_RS11215	COG1363	Peptidase, m42
CDM120_RS11225	COG1160	GTP binding
CDM120_RS11230	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDM120_RS11270	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDM120_RS11285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDM120_RS11285	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDM120_RS11295	COG1151	hydroxylamine reductase activity
CDM120_RS11315	COG1301	dicarboxylic acid transport
CDM120_RS11320	COG1126	abc transporter atp-binding protein
CDM120_RS11345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDM120_RS11350	COG0437	4 iron, 4 sulfur cluster binding
CDM120_RS11355	COG0243	molybdopterin cofactor binding
CDM120_RS11360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDM120_RS11365	COG0596	Alpha beta hydrolase
CDM120_RS11390	COG1705	Flagellar rod assembly protein muramidase FlgJ
CDM120_RS11395	COG1554	hydrolase, family 65, central catalytic
CDM120_RS11400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDM120_RS11415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDM120_RS11435	COG1528	Iron-storage protein
CDM120_RS11455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CDM120_RS11455	COG0674	pyruvate-flavodoxin oxidoreductase activity
CDM120_RS11465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDM120_RS11480	COG1309	transcriptional regulator
CDM120_RS11485	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CDM120_RS11490	COG0628	permease
CDM120_RS11495	COG1012	belongs to the aldehyde dehydrogenase family
CDM120_RS11510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDM120_RS11515	COG1132	(ABC) transporter
CDM120_RS11535	COG0288	reversible hydration of carbon dioxide
CDM120_RS11555	COG0710	3-dehydroquinate dehydratase activity
CDM120_RS11565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDM120_RS11625	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDM120_RS11630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDM120_RS11635	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CDM120_RS11650	COG2203	Gaf domain
CDM120_RS11650	COG3706	GGDEF domain
CDM120_RS11650	COG4251	negative regulation of phosphorylation
CDM120_RS11650	COG5001	Diguanylate cyclase
CDM120_RS11655	COG0017	Asparaginyl-tRNA synthetase
CDM120_RS11670	COG1404	Belongs to the peptidase S8 family
CDM120_RS11680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDM120_RS11695	COG1509	lysine 2,3-aminomutase activity
CDM120_RS11705	COG1794	racemase activity, acting on amino acids and derivatives
CDM120_RS11725	COG0662	Cupin 2, conserved barrel domain protein
CDM120_RS11730	COG3104	oligopeptide transport
CDM120_RS11735	COG0006	proline dipeptidase activity
CDM120_RS11740	COG3104	oligopeptide transport
CDM120_RS11745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDM120_RS11760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDM120_RS11760	COG0723	plastoquinol--plastocyanin reductase activity
CDM120_RS11770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS11770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS11770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS11775	COG1105	Belongs to the carbohydrate kinase PfkB family
CDM120_RS11780	COG3711	transcriptional antiterminator
CDM120_RS11780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS11785	COG2365	Tyrosine phosphatase family
CDM120_RS11805	COG1115	amino acid carrier protein
CDM120_RS11810	COG0235	Class ii aldolase
CDM120_RS11815	COG0235	Class ii aldolase
CDM120_RS11820	COG1063	alcohol dehydrogenase
CDM120_RS11825	COG3775	system Galactitol-specific IIC component
CDM120_RS11830	COG3414	Phosphotransferase system galactitol-specific IIB component
CDM120_RS11835	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS11835	COG2213	PTS system mannitol-specific
CDM120_RS11840	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDM120_RS11840	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDM120_RS11860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDM120_RS11865	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CDM120_RS11875	COG5002	protein histidine kinase activity
CDM120_RS11935	COG3620	sequence-specific DNA binding
CDM120_RS11985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDM120_RS11990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDM120_RS11995	COG0698	ribose 5-phosphate isomerase
CDM120_RS12000	COG3958	Transketolase
CDM120_RS12005	COG3959	Transketolase, thiamine diphosphate binding domain
CDM120_RS12015	COG1063	alcohol dehydrogenase
CDM120_RS12020	COG3775	system Galactitol-specific IIC component
CDM120_RS12025	COG3414	Phosphotransferase system galactitol-specific IIB component
CDM120_RS12035	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDM120_RS12035	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDM120_RS12040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDM120_RS12045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDM120_RS12050	COG0246	Mannitol dehydrogenase
CDM120_RS12055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS12060	COG3711	transcriptional antiterminator
CDM120_RS12070	COG0516	GMP reductase activity
CDM120_RS12070	COG0517	IMP dehydrogenase activity
CDM120_RS12075	COG3853	Toxic anion resistance protein (TelA)
CDM120_RS12085	COG1454	alcohol dehydrogenase
CDM120_RS12090	COG0427	acetyl-CoA hydrolase
CDM120_RS12105	COG1012	belongs to the aldehyde dehydrogenase family
CDM120_RS12110	COG0427	acetyl-CoA hydrolase
CDM120_RS12115	COG0490	domain, Protein
CDM120_RS12115	COG2985	domain, Protein
CDM120_RS12115	COG0490	domain, Protein
CDM120_RS12115	COG2985	domain, Protein
CDM120_RS12120	COG0583	DNA-binding transcription factor activity
CDM120_RS12130	COG0006	proline dipeptidase activity
CDM120_RS12145	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CDM120_RS12170	COG3118	belongs to the thioredoxin family
CDM120_RS12190	COG0561	phosphatase activity
CDM120_RS12205	COG1116	anion transmembrane transporter activity
CDM120_RS12215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDM120_RS12255	COG0157	Belongs to the NadC ModD family
CDM120_RS12265	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDM120_RS12270	COG1966	Carbon starvation protein
CDM120_RS12285	COG0628	permease
CDM120_RS12295	COG2364	Membrane
CDM120_RS12300	COG3426	butyrate kinase activity
CDM120_RS12325	COG2199	diguanylate cyclase activity
CDM120_RS12330	COG2203	Gaf domain
CDM120_RS12330	COG2199	diguanylate cyclase activity
CDM120_RS12385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDM120_RS12385	COG0072	phenylalanine-tRNA ligase activity
CDM120_RS12390	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDM120_RS12395	COG2176	DNA-directed DNA polymerase activity
CDM120_RS12415	COG0037	tRNA processing
CDM120_RS12430	COG3546	catalase activity
CDM120_RS12435	COG1388	LysM domain
CDM120_RS12435	COG3103	Sh3 type 3 domain protein
CDM120_RS12435	COG0791	NLP P60 protein
CDM120_RS12445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDM120_RS12445	COG0551	DNA topoisomerase type I activity
CDM120_RS12475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDM120_RS12475	COG0574	Belongs to the PEP-utilizing enzyme family
CDM120_RS12480	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CDM120_RS12485	COG0517	IMP dehydrogenase activity
CDM120_RS12505	COG3711	transcriptional antiterminator
CDM120_RS12505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS12510	COG3732	PTS system glucitol sorbitol-specific
CDM120_RS12520	COG2207	Transcriptional regulator
CDM120_RS12530	COG1288	antiporter activity
CDM120_RS12540	COG1115	amino acid carrier protein
CDM120_RS12545	COG2223	nitrite transmembrane transporter activity
CDM120_RS12550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDM120_RS12555	COG0280	phosphate acetyltransferase
CDM120_RS12575	COG0674	pyruvate-flavodoxin oxidoreductase activity
CDM120_RS12575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CDM120_RS12585	COG1414	Transcriptional regulator
CDM120_RS12595	COG0751	glycine-tRNA ligase activity
CDM120_RS12600	COG0752	glycyl-tRNA synthetase alpha subunit
CDM120_RS12610	COG1381	Involved in DNA repair and RecF pathway recombination
CDM120_RS12620	COG2239	Acts as a magnesium transporter
CDM120_RS12625	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDM120_RS12630	COG0295	cytidine deaminase activity
CDM120_RS12635	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CDM120_RS12640	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDM120_RS12645	COG1702	phosphate starvation-inducible protein PhoH
CDM120_RS12660	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CDM120_RS12665	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CDM120_RS12670	COG1610	YqeY-like protein
CDM120_RS12675	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDM120_RS12680	COG0537	adenosine 5'-monophosphoramidase activity
CDM120_RS12685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDM120_RS12690	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDM120_RS12695	COG2264	protein methyltransferase activity
CDM120_RS12725	COG3842	ATPase activity
CDM120_RS12730	COG2508	Transcriptional regulator
CDM120_RS12735	COG0477	Major facilitator Superfamily
CDM120_RS12750	COG0484	heat shock protein binding
CDM120_RS12755	COG0443	Heat shock 70 kDa protein
CDM120_RS12760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDM120_RS12765	COG1420	regulation of RNA biosynthetic process
CDM120_RS12770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDM120_RS12775	COG0531	amino acid
CDM120_RS12780	COG0617	tRNA 3'-terminal CCA addition
CDM120_RS12785	COG0481	GTPase activity
CDM120_RS12810	COG0268	Binds directly to 16S ribosomal RNA
CDM120_RS12820	COG0658	competence protein
CDM120_RS12820	COG2333	competence protein COMEC
CDM120_RS12835	COG2333	competence protein COMEC
CDM120_RS12835	COG0658	competence protein
CDM120_RS12840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDM120_RS12845	COG1388	LysM domain
CDM120_RS12845	COG3584	3D domain protein
CDM120_RS12850	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDM120_RS12870	COG1396	sequence-specific DNA binding
CDM120_RS12875	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDM120_RS12880	COG0006	proline dipeptidase activity
CDM120_RS12885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS12890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS12900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS12900	COG3711	transcriptional antiterminator
CDM120_RS12905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDM120_RS12910	COG1482	cell wall glycoprotein biosynthetic process
CDM120_RS12915	COG5002	protein histidine kinase activity
CDM120_RS12930	COG0709	Synthesizes selenophosphate from selenide and ATP
CDM120_RS12940	COG1686	Belongs to the peptidase S11 family
CDM120_RS12950	COG0165	Argininosuccinate lyase
CDM120_RS12955	COG0561	phosphatase activity
CDM120_RS12960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDM120_RS12965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDM120_RS12970	COG1876	peptidase activity
CDM120_RS12975	COG1309	transcriptional regulator
CDM120_RS12980	COG2814	Major facilitator Superfamily
CDM120_RS13000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS13000	COG1263	PTS System
CDM120_RS13005	COG3711	transcriptional antiterminator
CDM120_RS13010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS13010	COG1263	PTS System
CDM120_RS13010	COG2190	(PTS) system
CDM120_RS13015	COG0251	oxidation-reduction process
CDM120_RS13020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDM120_RS13055	COG0495	leucyl-tRNA aminoacylation
CDM120_RS13060	COG0799	negative regulation of ribosome biogenesis
CDM120_RS13065	COG1713	HD superfamily hydrolase involved in NAD metabolism
CDM120_RS13070	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDM120_RS13080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDM120_RS13085	COG1309	transcriptional regulator
CDM120_RS13130	COG0577	efflux transmembrane transporter activity
CDM120_RS13130	COG1136	(ABC) transporter
CDM120_RS13140	COG0745	RESPONSE REGULATOR receiver
CDM120_RS13145	COG0737	Belongs to the 5'-nucleotidase family
CDM120_RS13155	COG1234	tRNA 3'-trailer cleavage
CDM120_RS13160	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDM120_RS13165	COG1823	symporter activity
CDM120_RS13190	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDM120_RS13190	COG4124	Belongs to the glycosyl hydrolase 26 family
CDM120_RS13205	COG0395	ABC-type sugar transport system, permease component
CDM120_RS13230	COG0742	ribosomal rna small subunit methyltransferase
CDM120_RS13235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDM120_RS13240	COG1461	Dihydroxyacetone kinase
CDM120_RS13245	COG1302	Protein conserved in bacteria
CDM120_RS13250	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDM120_RS13265	COG0789	Transcriptional regulator
CDM120_RS13270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS13270	COG3711	transcriptional antiterminator
CDM120_RS13275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS13275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS13275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS13280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS13280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS13280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS13285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS13290	COG0383	alpha-mannosidase activity
CDM120_RS13295	COG5002	protein histidine kinase activity
CDM120_RS13315	COG1564	THIamine pyrophosphokinase
CDM120_RS13320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDM120_RS13325	COG1162	GTPase activity
CDM120_RS13330	COG1028	Short-chain dehydrogenase reductase Sdr
CDM120_RS13335	COG0515	serine threonine protein kinase
CDM120_RS13335	COG2815	serine threonine protein kinase
CDM120_RS13345	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDM120_RS13350	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDM120_RS13350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDM120_RS13355	COG2738	Putative neutral zinc metallopeptidase
CDM120_RS13365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDM120_RS13370	COG0242	peptide deformylase activity
CDM120_RS13375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDM120_RS13380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDM120_RS13385	COG1758	RNA polymerase activity
CDM120_RS13390	COG0194	GDP metabolic process
CDM120_RS13395	COG1561	YicC-like family, N-terminal region
CDM120_RS13400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDM120_RS13410	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CDM120_RS13415	COG0488	(ABC) transporter
CDM120_RS13425	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CDM120_RS13430	COG0564	pseudouridine synthase activity
CDM120_RS13435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDM120_RS13445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDM120_RS13450	COG1966	Carbon starvation protein
CDM120_RS13455	COG3279	Response regulator of the LytR AlgR family
CDM120_RS13460	COG3275	phosphorelay sensor kinase activity
CDM120_RS13490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDM120_RS13495	COG0531	amino acid
CDM120_RS13500	COG0006	proline dipeptidase activity
CDM120_RS13505	COG1307	EDD domain protein, DegV family
CDM120_RS13520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDM120_RS13525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDM120_RS13535	COG2302	S4 RNA-binding domain
CDM120_RS13545	COG1799	cell septum assembly
CDM120_RS13550	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CDM120_RS13570	COG3830	Belongs to the UPF0237 family
CDM120_RS13580	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CDM120_RS13595	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDM120_RS13600	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CDM120_RS13605	COG1160	GTP binding
CDM120_RS13630	COG5002	protein histidine kinase activity
CDM120_RS13635	COG0745	RESPONSE REGULATOR receiver
CDM120_RS13645	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDM120_RS13650	COG1873	PFAM PRC-barrel domain
CDM120_RS13655	COG1191	sigma factor activity
CDM120_RS13660	COG1191	sigma factor activity
CDM120_RS13675	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDM120_RS13680	COG3856	small basic protein
CDM120_RS13700	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDM120_RS13705	COG0772	Belongs to the SEDS family
CDM120_RS13710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDM120_RS13715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDM120_RS13720	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDM120_RS13725	COG0768	penicillin binding
CDM120_RS13735	COG0275	rRNA processing
CDM120_RS13740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDM120_RS13745	COG0612	Peptidase, M16
CDM120_RS13755	COG0012	GTP binding
CDM120_RS13760	COG3300	MHYT domain
CDM120_RS13760	COG5001	Diguanylate cyclase
CDM120_RS13765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDM120_RS13775	COG1263	PTS System
CDM120_RS13775	COG2190	(PTS) system
CDM120_RS13775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS13780	COG3711	transcriptional antiterminator
CDM120_RS13785	COG0025	NhaP-type Na H and K H
CDM120_RS13790	COG4608	Belongs to the ABC transporter superfamily
CDM120_RS13795	COG0444	Belongs to the ABC transporter superfamily
CDM120_RS13805	COG0601	transmembrane transport
CDM120_RS13810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDM120_RS13815	COG0583	DNA-binding transcription factor activity
CDM120_RS13820	COG0183	Belongs to the thiolase family
CDM120_RS13825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDM120_RS13835	COG1028	Short-chain dehydrogenase reductase Sdr
CDM120_RS13840	COG2610	gluconate transmembrane transporter activity
CDM120_RS13845	COG2340	Cysteine-rich secretory protein family
CDM120_RS13855	COG4869	propanediol catabolic process
CDM120_RS13890	COG2081	HI0933 family
CDM120_RS13895	COG0671	phosphoesterase, PA-phosphatase related
CDM120_RS13905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDM120_RS13940	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDM120_RS13940	COG1388	LysM domain
CDM120_RS13960	COG2502	aspartate--ammonia ligase
CDM120_RS13965	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDM120_RS13975	COG3366	ferrous iron transmembrane transporter activity
CDM120_RS13995	COG2252	PERMEase
CDM120_RS14000	COG0402	S-adenosylhomocysteine deaminase activity
CDM120_RS14010	COG2271	Major facilitator Superfamily
CDM120_RS14030	COG0583	DNA-binding transcription factor activity
CDM120_RS14040	COG1376	ErfK ybiS ycfS ynhG family protein
CDM120_RS14045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDM120_RS14050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDM120_RS14070	COG4509	Sortase family
CDM120_RS14090	COG0726	polysaccharide deacetylase
CDM120_RS14095	COG3069	C4-dicarboxylate transmembrane transporter activity
CDM120_RS14100	COG5002	protein histidine kinase activity
CDM120_RS14100	COG0642	Histidine kinase
CDM120_RS14105	COG0745	RESPONSE REGULATOR receiver
CDM120_RS14120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDM120_RS14125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDM120_RS14145	COG1937	Protein conserved in bacteria
CDM120_RS14170	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDM120_RS14175	COG1757	Na H antiporter
CDM120_RS14185	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDM120_RS14185	COG2247	cell wall binding repeat
CDM120_RS14190	COG0583	DNA-binding transcription factor activity
CDM120_RS14195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDM120_RS14205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDM120_RS14210	COG0124	histidyl-tRNA synthetase
CDM120_RS14215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDM120_RS14220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDM120_RS14225	COG1490	D-aminoacyl-tRNA deacylase activity
CDM120_RS14230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDM120_RS14235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDM120_RS14240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CDM120_RS14240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDM120_RS14285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS14310	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDM120_RS14315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDM120_RS14325	COG0561	phosphatase activity
CDM120_RS14330	COG1316	TRANSCRIPTIONal
CDM120_RS14335	COG1316	TRANSCRIPTIONal
CDM120_RS14340	COG1649	PFAM Uncharacterised BCR, COG1649
CDM120_RS14345	COG0791	NLP P60 protein
CDM120_RS14355	COG0438	transferase activity, transferring glycosyl groups
CDM120_RS14360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDM120_RS14365	COG1215	transferase activity, transferring glycosyl groups
CDM120_RS14375	COG1215	transferase activity, transferring glycosyl groups
CDM120_RS14380	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CDM120_RS14380	COG1215	transferase activity, transferring glycosyl groups
CDM120_RS14385	COG1216	Glycosyl transferase, family 2
CDM120_RS14405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDM120_RS14410	COG0728	peptidoglycan biosynthetic process
CDM120_RS14415	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDM120_RS14415	COG2247	cell wall binding repeat
CDM120_RS14420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDM120_RS14425	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDM120_RS14435	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDM120_RS14435	COG2247	cell wall binding repeat
CDM120_RS14445	COG2246	polysaccharide biosynthetic process
CDM120_RS14450	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDM120_RS14450	COG2247	cell wall binding repeat
CDM120_RS14465	COG0653	protein targeting
CDM120_RS14490	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDM120_RS14490	COG2247	cell wall binding repeat
CDM120_RS14510	COG0343	queuine tRNA-ribosyltransferase activity
CDM120_RS14520	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDM120_RS14525	COG2255	four-way junction helicase activity
CDM120_RS14530	COG0632	four-way junction helicase activity
CDM120_RS14535	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CDM120_RS14570	COG2610	gluconate transmembrane transporter activity
CDM120_RS14575	COG2084	Dehydrogenase
CDM120_RS14595	COG1132	(ABC) transporter
CDM120_RS14605	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CDM120_RS14640	COG0436	Aminotransferase
CDM120_RS14645	COG0697	spore germination
CDM120_RS14660	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDM120_RS14670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDM120_RS14675	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CDM120_RS14680	COG1473	amidohydrolase
CDM120_RS14685	COG3949	Membrane
CDM120_RS14700	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDM120_RS14715	COG0604	alcohol dehydrogenase
CDM120_RS14725	COG1592	Rubrerythrin
CDM120_RS14730	COG0789	Transcriptional regulator
CDM120_RS14740	COG1664	Polymer-forming cytoskeletal
CDM120_RS14745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDM120_RS14745	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDM120_RS14750	COG1349	DNA-binding transcription factor activity
CDM120_RS14755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDM120_RS14760	COG1696	Membrane protein involved in D-alanine export
CDM120_RS14765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDM120_RS14775	COG0673	inositol 2-dehydrogenase activity
CDM120_RS14785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDM120_RS14790	COG1253	flavin adenine dinucleotide binding
CDM120_RS14795	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CDM120_RS14815	COG3290	protein histidine kinase activity
CDM120_RS14815	COG3829	transcription factor binding
CDM120_RS14820	COG2267	carboxylic ester hydrolase activity
CDM120_RS14830	COG0312	modulator of DNA gyrase
CDM120_RS14835	COG0312	modulator of DNA gyrase
CDM120_RS14875	COG1120	ATPase activity
CDM120_RS14885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDM120_RS14900	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDM120_RS14905	COG3394	polysaccharide catabolic process
CDM120_RS14910	COG1486	melibiose metabolic process
CDM120_RS14915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDM120_RS14925	COG2188	Transcriptional regulator
CDM120_RS14930	COG0366	Alpha amylase catalytic
CDM120_RS14935	COG1263	PTS System
CDM120_RS14935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS14945	COG2188	Transcriptional regulator
CDM120_RS14950	COG1178	ABC-type Fe3 transport system permease component
CDM120_RS14955	COG3842	ATPase activity
CDM120_RS14960	COG1840	ABC-type Fe3 transport system, periplasmic component
CDM120_RS14965	COG1394	ATPase activity, coupled to movement of substances
CDM120_RS14970	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
CDM120_RS14975	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
CDM120_RS14990	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
CDM120_RS14995	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDM120_RS15000	COG1269	ATP hydrolysis coupled proton transport
CDM120_RS15025	COG5001	Diguanylate cyclase
CDM120_RS15025	COG3300	MHYT domain
CDM120_RS15030	COG1454	alcohol dehydrogenase
CDM120_RS15030	COG1012	belongs to the aldehyde dehydrogenase family
CDM120_RS15040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDM120_RS15060	COG1268	BioY protein
CDM120_RS15075	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CDM120_RS15090	COG1203	CRISPR-associated helicase, Cas3
CDM120_RS15120	COG0577	efflux transmembrane transporter activity
CDM120_RS15125	COG1136	(ABC) transporter
CDM120_RS15130	COG1968	undecaprenyl-diphosphatase activity
CDM120_RS15135	COG2205	protein histidine kinase activity
CDM120_RS15140	COG0745	RESPONSE REGULATOR receiver
CDM120_RS15155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDM120_RS15175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDM120_RS15180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDM120_RS15190	COG1120	ATPase activity
CDM120_RS15195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDM120_RS15205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDM120_RS15210	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDM120_RS15235	COG1454	alcohol dehydrogenase
CDM120_RS15250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDM120_RS15255	COG0785	Cytochrome C biogenesis protein
CDM120_RS15260	COG1733	regulation of RNA biosynthetic process
CDM120_RS15265	COG0383	alpha-mannosidase activity
CDM120_RS15270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS15275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS15280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS15280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS15280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS15285	COG3711	transcriptional antiterminator
CDM120_RS15285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS15290	COG4975	Glucose uptake
CDM120_RS15310	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDM120_RS15330	COG5002	protein histidine kinase activity
CDM120_RS15340	COG0492	ferredoxin-NADP+ reductase activity
CDM120_RS15345	COG3118	belongs to the thioredoxin family
CDM120_RS15355	COG0384	phenazine biosynthesis protein PhzF
CDM120_RS15375	COG0542	response to heat
CDM120_RS15395	COG2267	carboxylic ester hydrolase activity
CDM120_RS15410	COG1737	Transcriptional regulator
CDM120_RS15420	COG2971	BadF BadG BcrA BcrD
CDM120_RS15425	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CDM120_RS15435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDM120_RS15450	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDM120_RS15455	COG0642	Histidine kinase
CDM120_RS15470	COG1136	(ABC) transporter
CDM120_RS15480	COG2190	(PTS) system
CDM120_RS15495	COG1263	PTS System
CDM120_RS15495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS15515	COG1070	Carbohydrate kinase
CDM120_RS15520	COG1940	carbohydrate kinase activity
CDM120_RS15530	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS15530	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS15535	COG3716	PTS system mannose fructose sorbose family IID component
CDM120_RS15560	COG0366	Alpha amylase catalytic
CDM120_RS15565	COG0191	fructose-bisphosphate aldolase activity
CDM120_RS15570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS15570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS15570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS15585	COG2723	6-phospho-beta-galactosidase activity
CDM120_RS15590	COG3394	polysaccharide catabolic process
CDM120_RS15595	COG1263	PTS System
CDM120_RS15595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS15595	COG2190	(PTS) system
CDM120_RS15600	COG2188	Transcriptional regulator
CDM120_RS15605	COG0366	Alpha amylase catalytic
CDM120_RS15615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDM120_RS15625	COG2723	6-phospho-beta-galactosidase activity
CDM120_RS15630	COG2723	6-phospho-beta-galactosidase activity
CDM120_RS15635	COG1263	PTS System
CDM120_RS15635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS15635	COG2190	(PTS) system
CDM120_RS15640	COG3711	transcriptional antiterminator
CDM120_RS15650	COG1288	antiporter activity
CDM120_RS15655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS15655	COG1263	PTS System
CDM120_RS15660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDM120_RS15670	COG1132	(ABC) transporter
CDM120_RS15675	COG1136	(ABC) transporter
CDM120_RS15690	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDM120_RS15700	COG0745	RESPONSE REGULATOR receiver
CDM120_RS15705	COG2190	(PTS) system
CDM120_RS15710	COG0561	phosphatase activity
CDM120_RS15715	COG1454	alcohol dehydrogenase
CDM120_RS15720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDM120_RS15725	COG3711	transcriptional antiterminator
CDM120_RS15725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS15730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDM120_RS15735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDM120_RS15740	COG0205	6-phosphofructokinase activity
CDM120_RS15760	COG1959	2 iron, 2 sulfur cluster binding
CDM120_RS15765	COG0778	Nitroreductase
CDM120_RS15770	COG2723	6-phospho-beta-galactosidase activity
CDM120_RS15775	COG1263	PTS System
CDM120_RS15775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS15775	COG2190	(PTS) system
CDM120_RS15785	COG1136	(ABC) transporter
CDM120_RS15810	COG1819	glycosyl
CDM120_RS15815	COG3620	sequence-specific DNA binding
CDM120_RS15825	COG2223	nitrite transmembrane transporter activity
CDM120_RS15830	COG1695	Transcriptional regulator
CDM120_RS15840	COG0640	Transcriptional regulator
CDM120_RS15850	COG2723	6-phospho-beta-galactosidase activity
CDM120_RS15855	COG2190	(PTS) system
CDM120_RS15855	COG1263	PTS System
CDM120_RS15855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS15860	COG3711	transcriptional antiterminator
CDM120_RS15865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS15865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS15865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS15870	COG3711	transcriptional antiterminator
CDM120_RS15875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS15875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDM120_RS15875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS15880	COG0191	fructose-bisphosphate aldolase activity
CDM120_RS15885	COG1178	ABC-type Fe3 transport system permease component
CDM120_RS15890	COG3842	ATPase activity
CDM120_RS15900	COG1840	ABC-type Fe3 transport system, periplasmic component
CDM120_RS15905	COG2723	6-phospho-beta-galactosidase activity
CDM120_RS15910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS15910	COG1263	PTS System
CDM120_RS15910	COG2190	(PTS) system
CDM120_RS15915	COG3711	transcriptional antiterminator
CDM120_RS15935	COG0693	protein deglycase activity
CDM120_RS15955	COG4509	Sortase family
CDM120_RS15985	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDM120_RS16015	COG0557	exoribonuclease II activity
CDM120_RS16030	COG1881	PFAM PEBP family protein
CDM120_RS16060	COG0148	phosphopyruvate hydratase activity
CDM120_RS16065	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CDM120_RS16070	COG0149	triose-phosphate isomerase activity
CDM120_RS16075	COG0126	phosphoglycerate kinase activity
CDM120_RS16085	COG2390	Transcriptional regulator
CDM120_RS16090	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDM120_RS16095	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDM120_RS16105	COG0167	dihydroorotate dehydrogenase activity
CDM120_RS16115	COG0402	S-adenosylhomocysteine deaminase activity
CDM120_RS16120	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CDM120_RS16135	COG3829	transcription factor binding
CDM120_RS16140	COG0251	oxidation-reduction process
CDM120_RS16155	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDM120_RS16160	COG0789	Transcriptional regulator
CDM120_RS16180	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDM120_RS16180	COG2247	cell wall binding repeat
CDM120_RS16185	COG1136	(ABC) transporter
CDM120_RS16190	COG0577	efflux transmembrane transporter activity
CDM120_RS16215	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDM120_RS16225	COG0789	Transcriptional regulator
CDM120_RS16250	COG2205	protein histidine kinase activity
CDM120_RS16250	COG2770	Histidine kinase
CDM120_RS16255	COG0745	RESPONSE REGULATOR receiver
CDM120_RS16260	COG0706	membrane insertase activity
CDM120_RS16270	COG0778	Nitroreductase
CDM120_RS16280	COG0534	Mate efflux family protein
CDM120_RS16315	COG1732	Glycine betaine
CDM120_RS16320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDM120_RS16330	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDM120_RS16335	COG2226	methyltransferase
CDM120_RS16345	COG1473	amidohydrolase
CDM120_RS16350	COG1760	l-serine dehydratase
CDM120_RS16355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDM120_RS16360	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDM120_RS16365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDM120_RS16370	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDM120_RS16375	COG2171	N-acyltransferase activity
CDM120_RS16385	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDM120_RS16395	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CDM120_RS16400	COG3681	Belongs to the UPF0597 family
CDM120_RS16410	COG3829	transcription factor binding
CDM120_RS16415	COG2226	methyltransferase
CDM120_RS16440	COG0252	asparaginase activity
CDM120_RS16440	COG5275	peptidyl-tyrosine sulfation
CDM120_RS16445	COG0252	asparaginase activity
CDM120_RS16445	COG5275	peptidyl-tyrosine sulfation
CDM120_RS16450	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CDM120_RS16455	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CDM120_RS16465	COG5275	peptidyl-tyrosine sulfation
CDM120_RS16465	COG0252	asparaginase activity
CDM120_RS16480	COG4656	Part of a membrane complex involved in electron transport
CDM120_RS16490	COG0726	polysaccharide deacetylase
CDM120_RS16515	COG0285	dihydrofolate synthase activity
CDM120_RS16525	COG3279	Response regulator of the LytR AlgR family
CDM120_RS16530	COG0525	valine-tRNA ligase activity
CDM120_RS16535	COG0726	polysaccharide deacetylase
CDM120_RS16550	COG0704	Plays a role in the regulation of phosphate uptake
CDM120_RS16555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDM120_RS16560	COG0581	inorganic phosphate transmembrane transporter activity
CDM120_RS16565	COG0573	inorganic phosphate transmembrane transporter activity
CDM120_RS16580	COG0745	RESPONSE REGULATOR receiver
CDM120_RS16585	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDM120_RS16590	COG1164	Oligoendopeptidase f
CDM120_RS16595	COG1285	pathogenesis
CDM120_RS16615	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CDM120_RS16620	COG3716	PTS system mannose fructose sorbose family IID component
CDM120_RS16625	COG3715	PTS system
CDM120_RS16630	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS16630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS16635	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDM120_RS16635	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDM120_RS16645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDM120_RS16660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDM120_RS16665	COG0166	Belongs to the GPI family
CDM120_RS16675	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CDM120_RS16690	COG3012	SEC-C Motif Domain Protein
CDM120_RS16690	COG1405	negative regulation of cell septum assembly
CDM120_RS16715	COG1459	type II secretion system
CDM120_RS16720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDM120_RS16735	COG2814	Major facilitator Superfamily
CDM120_RS16740	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CDM120_RS16745	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDM120_RS16755	COG2059	Chromate
CDM120_RS16760	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDM120_RS16765	COG0740	serine-type endopeptidase activity
CDM120_RS16770	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDM120_RS16785	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDM120_RS16840	COG2946	Replication initiation factor
CDM120_RS16860	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDM120_RS16860	COG0493	'glutamate synthase
CDM120_RS16870	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDM120_RS16880	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDM120_RS16885	COG3383	formate dehydrogenase (NAD+) activity
CDM120_RS16890	COG3383	formate dehydrogenase (NAD+) activity
CDM120_RS16940	COG0463	Glycosyl transferase, family 2
CDM120_RS16940	COG0457	Tetratricopeptide repeat
CDM120_RS16955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDM120_RS16965	COG0778	Nitroreductase
CDM120_RS16970	COG1733	regulation of RNA biosynthetic process
CDM120_RS16985	COG0488	(ABC) transporter
CDM120_RS16990	COG0745	RESPONSE REGULATOR receiver
CDM120_RS17010	COG4555	ABC transporter
CDM120_RS17015	COG2199	diguanylate cyclase activity
CDM120_RS17055	COG0205	6-phosphofructokinase activity
CDM120_RS17065	COG1481	regulation of sporulation
CDM120_RS17080	COG1660	Displays ATPase and GTPase activities
CDM120_RS17090	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDM120_RS17095	COG2116	formate transmembrane transporter activity
CDM120_RS17100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDM120_RS17130	COG0322	excinuclease ABC activity
CDM120_RS17140	COG0556	nucleotide-excision repair
CDM120_RS17150	COG1653	transport
CDM120_RS17160	COG1175	transmembrane transport
CDM120_RS17165	COG3842	ATPase activity
CDM120_RS17185	COG1648	precorrin-2 dehydrogenase activity
CDM120_RS17185	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDM120_RS17190	COG0113	porphobilinogen synthase activity
CDM120_RS17200	COG0181	hydroxymethylbilane synthase activity
CDM120_RS17240	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CDM120_RS17255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDM120_RS17265	COG1797	cobyrinic acid a,c-diamide synthase activity
CDM120_RS17270	COG1492	cobalamin metabolic process
CDM120_RS17280	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CDM120_RS17290	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDM120_RS17310	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDM120_RS17325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDM120_RS17330	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDM120_RS17335	COG1363	Peptidase, m42
CDM120_RS17340	COG3711	transcriptional antiterminator
CDM120_RS17345	COG0191	fructose-bisphosphate aldolase activity
CDM120_RS17350	COG2222	sugar isomerase
CDM120_RS17355	COG0673	inositol 2-dehydrogenase activity
CDM120_RS17365	COG2188	Transcriptional regulator
CDM120_RS17375	COG3409	Peptidoglycan-binding domain 1 protein
CDM120_RS17375	COG0793	Belongs to the peptidase S41A family
CDM120_RS17380	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDM120_RS17390	COG3949	Membrane
CDM120_RS17395	COG3958	Transketolase
CDM120_RS17400	COG3959	Transketolase, thiamine diphosphate binding domain
CDM120_RS17405	COG2337	Toxic component of a toxin-antitoxin (TA) module
CDM120_RS17425	COG0516	GMP reductase activity
CDM120_RS17425	COG0517	IMP dehydrogenase activity
CDM120_RS17430	COG0736	holo-[acyl-carrier-protein] synthase activity
CDM120_RS17435	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDM120_RS17440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDM120_RS17445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDM120_RS17450	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDM120_RS17455	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDM120_RS17460	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDM120_RS17465	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDM120_RS17490	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDM120_RS17490	COG3608	succinylglutamate desuccinylase aspartoacylase
CDM120_RS17495	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDM120_RS17500	COG0698	ribose 5-phosphate isomerase
CDM120_RS17505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDM120_RS17510	COG0009	L-threonylcarbamoyladenylate synthase
CDM120_RS17520	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDM120_RS17525	COG2890	protein-(glutamine-N5) methyltransferase activity
CDM120_RS17530	COG3872	metal-dependent enzyme
CDM120_RS17535	COG0254	rRNA binding
CDM120_RS17540	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDM120_RS17545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDM120_RS17555	COG2208	phosphoserine phosphatase activity
CDM120_RS17560	COG0248	Ppx GppA phosphatase
CDM120_RS17580	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDM120_RS17590	COG3956	TIGRFAM MazG family protein
CDM120_RS17595	COG2244	polysaccharide biosynthetic process
CDM120_RS17600	COG2002	toxin-antitoxin pair type II binding
CDM120_RS17605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDM120_RS17610	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDM120_RS17615	COG0193	aminoacyl-tRNA hydrolase activity
CDM120_RS17665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDM120_RS17680	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDM120_RS17685	COG2088	sporulation resulting in formation of a cellular spore
CDM120_RS17690	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDM120_RS17695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDM120_RS17705	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDM120_RS17710	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDM120_RS17720	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDM120_RS17725	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CDM120_RS17740	COG3842	ATPase activity
CDM120_RS17745	COG0613	PHP domain protein
CDM120_RS17760	COG0084	hydrolase, TatD family'
CDM120_RS17765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDM120_RS17765	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDM120_RS17770	COG0700	Nucleoside recognition
CDM120_RS17780	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDM120_RS17785	COG1522	sequence-specific DNA binding
CDM120_RS17790	COG0617	tRNA 3'-terminal CCA addition
CDM120_RS17795	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CDM120_RS17800	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CDM120_RS17805	COG1774	PSP1 C-terminal conserved region
CDM120_RS17810	COG0470	DNA polymerase III
CDM120_RS17820	COG1982	Orn Lys Arg decarboxylase major
CDM120_RS17825	COG2155	Conserved Protein
CDM120_RS17850	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDM120_RS17855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDM120_RS17865	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CDM120_RS17875	COG3191	aminopeptidase activity
CDM120_RS17885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDM120_RS17890	COG0037	tRNA processing
CDM120_RS17900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDM120_RS17915	COG1802	Transcriptional regulator
CDM120_RS17920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDM120_RS17950	COG0653	protein targeting
CDM120_RS17975	COG2223	nitrite transmembrane transporter activity
CDM120_RS17980	COG0626	cystathionine gamma-synthase activity
CDM120_RS18005	COG0564	pseudouridine synthase activity
CDM120_RS18010	COG4978	Transcriptional regulator
CDM120_RS18010	COG0789	Transcriptional regulator
CDM120_RS18020	COG0577	efflux transmembrane transporter activity
CDM120_RS18020	COG1136	(ABC) transporter
CDM120_RS18025	COG2205	protein histidine kinase activity
CDM120_RS18040	COG1695	Transcriptional regulator
CDM120_RS18055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDM120_RS18065	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDM120_RS18075	COG0284	orotidine-5'-phosphate decarboxylase activity
CDM120_RS18095	COG1410	methionine synthase
CDM120_RS18095	COG0646	methionine synthase
CDM120_RS18105	COG1854	S-ribosylhomocysteine lyase activity
CDM120_RS18120	COG1876	peptidase activity
CDM120_RS18125	COG0037	tRNA processing
CDM120_RS18130	COG1408	metallophosphoesterase
CDM120_RS18145	COG1141	Ferredoxin
CDM120_RS18150	COG3964	amidohydrolase
CDM120_RS18160	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDM120_RS18170	COG0346	lactoylglutathione lyase activity
CDM120_RS18175	COG0534	Mate efflux family protein
CDM120_RS18190	COG0789	Transcriptional regulator
CDM120_RS18190	COG4978	Transcriptional regulator
CDM120_RS18195	COG3263	regulation of cellular component size
CDM120_RS18200	COG5504	Zn-dependent protease
CDM120_RS18210	COG0519	Catalyzes the synthesis of GMP from XMP
CDM120_RS18220	COG1357	PFAM Pentapeptide repeats (8 copies)
CDM120_RS18225	COG2824	Alkylphosphonate utilization operon protein PhnA
CDM120_RS18230	COG0577	efflux transmembrane transporter activity
CDM120_RS18230	COG1136	(ABC) transporter
CDM120_RS18240	COG5001	Diguanylate cyclase
CDM120_RS18240	COG3447	MASE1 domain protein
CDM120_RS18240	COG5002	protein histidine kinase activity
CDM120_RS18250	COG1473	amidohydrolase
CDM120_RS18265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDM120_RS18270	COG0517	IMP dehydrogenase activity
CDM120_RS18270	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDM120_RS18290	COG1335	isochorismatase
CDM120_RS18320	COG0583	DNA-binding transcription factor activity
CDM120_RS18325	COG1522	sequence-specific DNA binding
CDM120_RS18325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDM120_RS18340	COG3964	amidohydrolase
CDM120_RS18350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDM120_RS18355	COG2188	Transcriptional regulator
CDM120_RS18360	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDM120_RS18365	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDM120_RS18370	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDM120_RS18375	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDM120_RS18380	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CDM120_RS18395	COG1484	DNA-dependent DNA replication
CDM120_RS18420	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDM120_RS18430	COG0305	Participates in initiation and elongation during chromosome replication
CDM120_RS18435	COG0359	binds to the 23S rRNA
CDM120_RS18440	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CDM120_RS18455	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDM120_RS18460	COG0629	single-stranded DNA binding
CDM120_RS18465	COG0360	Binds together with S18 to 16S ribosomal RNA
CDM120_RS18470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDM120_RS18485	COG0425	Belongs to the sulfur carrier protein TusA family
CDM120_RS18500	COG1104	cysteine desulfurase activity
CDM120_RS18505	COG1475	DNA binding
CDM120_RS18510	COG1192	Involved in chromosome partitioning
CDM120_RS18515	COG1475	DNA binding
CDM120_RS18520	COG0357	Ribosomal RNA small subunit methyltransferase G
CDM120_RS18525	COG0445	tRNA wobble uridine modification
CDM120_RS18530	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDM120_RS18535	COG1847	R3H domain protein
CDM120_RS18540	COG0706	membrane insertase activity
CDM120_RS18545	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDM120_RS18550	COG0594	ribonuclease P activity
CDM120_RS18555	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CDM120_RS18585	COG1376	ErfK ybiS ycfS ynhG family protein