locus-tag	class	description
DTO10_RS00030	COG1388	LysM domain
DTO10_RS00030	COG3942	CHAP domain
DTO10_RS00055	COG2244	polysaccharide biosynthetic process
DTO10_RS00085	COG0583	DNA-binding transcription factor activity
DTO10_RS00095	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DTO10_RS00100	COG1174	glycine betaine transport
DTO10_RS00105	COG1732	Glycine betaine
DTO10_RS00110	COG1174	glycine betaine transport
DTO10_RS00115	COG1125	glycine betaine transport
DTO10_RS00115	COG0517	IMP dehydrogenase activity
DTO10_RS00120	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS00125	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DTO10_RS00130	COG2801	Transposase and inactivated derivatives
DTO10_RS00135	COG2259	Doxx family
DTO10_RS00140	COG0501	Belongs to the peptidase M48B family
DTO10_RS00160	COG0702	epimerase
DTO10_RS00165	COG0406	alpha-ribazole phosphatase activity
DTO10_RS00185	COG0708	Exodeoxyribonuclease III
DTO10_RS00190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DTO10_RS00195	COG0297	glycogen (starch) synthase activity
DTO10_RS00200	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DTO10_RS00205	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DTO10_RS00210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DTO10_RS00230	COG3663	DNA glycosylase
DTO10_RS00235	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DTO10_RS00240	COG0791	NLP P60 protein
DTO10_RS00240	COG1388	LysM domain
DTO10_RS00255	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS00260	COG3835	regulator
DTO10_RS00265	COG0730	response to heat
DTO10_RS00290	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DTO10_RS00295	COG0529	Catalyzes the synthesis of activated sulfate
DTO10_RS00300	COG2046	Belongs to the sulfate adenylyltransferase family
DTO10_RS00305	COG0175	sulfate reduction
DTO10_RS00315	COG0431	NADPH-dependent FMN reductase
DTO10_RS00330	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DTO10_RS00335	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DTO10_RS00340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_RS00355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DTO10_RS00360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DTO10_RS00370	COG1164	Oligoendopeptidase f
DTO10_RS00380	COG3403	YqcI/YcgG family
DTO10_RS00395	COG2197	response regulator
DTO10_RS00405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DTO10_RS00410	COG2223	nitrite transmembrane transporter activity
DTO10_RS00415	COG2116	formate transmembrane transporter activity
DTO10_RS00420	COG0628	permease
DTO10_RS00430	COG1376	ErfK ybiS ycfS ynhG family protein
DTO10_RS00450	COG0765	amino acid transport
DTO10_RS00455	COG0765	amino acid transport
DTO10_RS00460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_RS00465	COG1126	abc transporter atp-binding protein
DTO10_RS00475	COG2323	membrane
DTO10_RS00485	COG0679	Auxin Efflux Carrier
DTO10_RS00490	COG0590	tRNA wobble adenosine to inosine editing
DTO10_RS00500	COG2706	6-phosphogluconolactonase activity
DTO10_RS00505	COG2356	endonuclease I
DTO10_RS00510	COG0494	nUDIX hydrolase
DTO10_RS00515	COG0737	Belongs to the 5'-nucleotidase family
DTO10_RS00525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DTO10_RS00530	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS00535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DTO10_RS00540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DTO10_RS00545	COG1278	Cold shock
DTO10_RS00550	COG1024	Enoyl-CoA hydratase
DTO10_RS00555	COG4608	Belongs to the ABC transporter superfamily
DTO10_RS00560	COG0444	Belongs to the ABC transporter superfamily
DTO10_RS00565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DTO10_RS00570	COG0601	transmembrane transport
DTO10_RS00575	COG4166	transmembrane transport
DTO10_RS00600	COG2176	DNA-directed DNA polymerase activity
DTO10_RS00605	COG1511	domain protein
DTO10_RS00615	COG0561	phosphatase activity
DTO10_RS00620	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DTO10_RS00630	COG1113	amino acid transport
DTO10_RS00645	COG3852	Histidine kinase
DTO10_RS00655	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS00660	COG1335	isochorismatase
DTO10_RS00670	COG0861	Integral membrane protein TerC family
DTO10_RS00675	COG0246	Mannitol dehydrogenase
DTO10_RS00680	COG1063	alcohol dehydrogenase
DTO10_RS00685	COG2721	sulfolactate sulfo-lyase activity
DTO10_RS00690	COG2207	Transcriptional regulator
DTO10_RS00695	COG2271	Major facilitator Superfamily
DTO10_RS00700	COG1609	Transcriptional regulator
DTO10_RS00705	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS00715	COG1063	alcohol dehydrogenase
DTO10_RS00720	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DTO10_RS00735	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS00740	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DTO10_RS00745	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DTO10_RS00750	COG1691	(AIR) carboxylase
DTO10_RS00755	COG1606	tRNA processing
DTO10_RS00765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DTO10_RS00770	COG0179	Fumarylacetoacetate (FAA) hydrolase
DTO10_RS00785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DTO10_RS00790	COG4948	Mandelate Racemase Muconate Lactonizing
DTO10_RS00795	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS00800	COG2721	sulfolactate sulfo-lyase activity
DTO10_RS00815	COG1414	Transcriptional regulator
DTO10_RS00820	COG0129	dihydroxy-acid dehydratase activity
DTO10_RS00830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DTO10_RS00835	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DTO10_RS00840	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DTO10_RS00845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DTO10_RS00855	COG1132	(ABC) transporter
DTO10_RS00870	COG1388	LysM domain
DTO10_RS00870	COG3858	chitin binding
DTO10_RS00875	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS00880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DTO10_RS00885	COG1937	Protein conserved in bacteria
DTO10_RS00895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DTO10_RS00900	COG0400	carboxylic ester hydrolase activity
DTO10_RS00905	COG0346	lactoylglutathione lyase activity
DTO10_RS00910	COG0346	lactoylglutathione lyase activity
DTO10_RS00925	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS00930	COG1764	response to oxidative stress
DTO10_RS00960	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DTO10_RS00965	COG1733	regulation of RNA biosynthetic process
DTO10_RS00970	COG0492	ferredoxin-NADP+ reductase activity
DTO10_RS00985	COG0823	Involved in the tonB-independent uptake of proteins
DTO10_RS00985	COG1506	peptidase
DTO10_RS00985	COG4946	Tricorn protease homolog
DTO10_RS00990	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DTO10_RS00995	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DTO10_RS01000	COG1131	(ABC) transporter
DTO10_RS01010	COG2814	Major facilitator Superfamily
DTO10_RS01015	COG5002	protein histidine kinase activity
DTO10_RS01020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_RS01035	COG0514	ATP-dependent DNA helicase (RecQ)
DTO10_RS01040	COG1388	LysM domain
DTO10_RS01040	COG3584	3D domain protein
DTO10_RS01055	COG3546	catalase activity
DTO10_RS01060	COG2996	Protein conserved in bacteria
DTO10_RS01065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DTO10_RS01080	COG1247	-acetyltransferase
DTO10_RS01085	COG3973	AAA domain
DTO10_RS01090	COG0488	(ABC) transporter
DTO10_RS01100	COG0477	Major facilitator Superfamily
DTO10_RS01105	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS01110	COG1309	transcriptional regulator
DTO10_RS01115	COG2268	Band 7 protein
DTO10_RS01120	COG1585	Membrane protein implicated in regulation of membrane protease activity
DTO10_RS01125	COG1268	BioY protein
DTO10_RS01135	COG1272	protein, Hemolysin III
DTO10_RS01140	COG3773	Cell wall hydrolase
DTO10_RS01145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DTO10_RS01150	COG0432	Pfam Uncharacterised protein family UPF0047
DTO10_RS01160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DTO10_RS01160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DTO10_RS01160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DTO10_RS01165	COG1105	Belongs to the carbohydrate kinase PfkB family
DTO10_RS01170	COG1349	DNA-binding transcription factor activity
DTO10_RS01175	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_RS01180	COG0567	Dehydrogenase, E1 component
DTO10_RS01185	COG3384	dioxygenase
DTO10_RS01195	COG1410	methionine synthase
DTO10_RS01195	COG0646	methionine synthase
DTO10_RS01200	COG0646	methionine synthase
DTO10_RS01200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DTO10_RS01205	COG2258	MOSC domain
DTO10_RS01210	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DTO10_RS01215	COG1793	dna ligase
DTO10_RS01215	COG3285	dna ligase
DTO10_RS01230	COG0288	reversible hydration of carbon dioxide
DTO10_RS01260	COG1346	cytolysis
DTO10_RS01290	COG0668	transmembrane transport
DTO10_RS01295	COG0534	Mate efflux family protein
DTO10_RS01300	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS01310	COG2340	Cysteine-rich secretory protein family
DTO10_RS01325	COG5002	protein histidine kinase activity
DTO10_RS01330	COG0745	RESPONSE REGULATOR receiver
DTO10_RS01350	COG0523	cobalamin synthesis protein
DTO10_RS01355	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DTO10_RS01360	COG0235	Class ii aldolase
DTO10_RS01365	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
DTO10_RS01370	COG1850	ribulose-bisphosphate carboxylase activity
DTO10_RS01375	COG0436	Aminotransferase
DTO10_RS01380	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
DTO10_RS01385	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DTO10_RS01390	COG1316	TRANSCRIPTIONal
DTO10_RS01395	COG0793	Belongs to the peptidase S41A family
DTO10_RS01395	COG3409	Peptidoglycan-binding domain 1 protein
DTO10_RS01400	COG0813	purine-nucleoside phosphorylase activity
DTO10_RS01415	COG4191	Histidine kinase
DTO10_RS01420	COG4479	Belongs to the UPF0346 family
DTO10_RS01425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DTO10_RS01450	COG1509	lysine 2,3-aminomutase activity
DTO10_RS01455	COG3829	transcription factor binding
DTO10_RS01460	COG0456	acetyltransferase
DTO10_RS01465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_RS01470	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DTO10_RS01475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DTO10_RS01480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DTO10_RS01490	COG1619	proteins homologs of microcin C7 resistance protein MccF
DTO10_RS01505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DTO10_RS01525	COG2755	lipolytic protein G-D-S-L family
DTO10_RS01530	COG1999	signal sequence binding
DTO10_RS01545	COG0805	protein transport
DTO10_RS01550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DTO10_RS01555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DTO10_RS01560	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DTO10_RS01580	COG0861	Integral membrane protein TerC family
DTO10_RS01590	COG0405	Gamma-glutamyltransferase
DTO10_RS01595	COG2136	Putative SAM-dependent methyltransferase
DTO10_RS01595	COG2521	methyltransferase
DTO10_RS01605	COG0129	dihydroxy-acid dehydratase activity
DTO10_RS01610	COG1413	lyase activity
DTO10_RS01615	COG0488	(ABC) transporter
DTO10_RS01620	COG1418	mRNA catabolic process
DTO10_RS01625	COG1307	EDD domain protein, DegV family
DTO10_RS01630	COG0386	Belongs to the glutathione peroxidase family
DTO10_RS01640	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DTO10_RS01650	COG2226	methyltransferase
DTO10_RS01655	COG1321	iron dependent repressor
DTO10_RS01710	COG1876	peptidase activity
DTO10_RS01715	COG2132	Multicopper oxidase
DTO10_RS01760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DTO10_RS01795	COG0753	catalase activity
DTO10_RS01805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DTO10_RS01810	COG3739	integral membrane protein
DTO10_RS01815	COG3655	Transcriptional regulator
DTO10_RS01835	COG2124	cytochrome p450
DTO10_RS01845	COG0666	response to abiotic stimulus
DTO10_RS01850	COG0590	tRNA wobble adenosine to inosine editing
DTO10_RS01855	COG0745	RESPONSE REGULATOR receiver
DTO10_RS01860	COG5002	protein histidine kinase activity
DTO10_RS01900	COG1511	domain protein
DTO10_RS01905	COG1309	transcriptional regulator
DTO10_RS01930	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DTO10_RS01940	COG1959	2 iron, 2 sulfur cluster binding
DTO10_RS01945	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DTO10_RS01955	COG0328	RNA-DNA hybrid ribonuclease activity
DTO10_RS01960	COG0328	RNA-DNA hybrid ribonuclease activity
DTO10_RS01975	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DTO10_RS01990	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DTO10_RS01995	COG1755	Isoprenylcysteine carboxyl methyltransferase
DTO10_RS02000	COG3424	synthase
DTO10_RS02005	COG2233	PERMEase
DTO10_RS02010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DTO10_RS02020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DTO10_RS02025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DTO10_RS02030	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DTO10_RS02035	COG1199	ATP-dependent helicase activity
DTO10_RS02040	COG1278	Cold shock
DTO10_RS02045	COG0116	Belongs to the methyltransferase superfamily
DTO10_RS02060	COG3599	regulation of cell shape
DTO10_RS02065	COG4474	Belongs to the UPF0398 family
DTO10_RS02075	COG3359	exonuclease
DTO10_RS02080	COG1205	dead DEAH box helicase
DTO10_RS02080	COG1111	helicase
DTO10_RS02085	COG2267	carboxylic ester hydrolase activity
DTO10_RS02115	COG3331	DNA recombination
DTO10_RS02120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DTO10_RS02120	COG4499	WXG100 protein secretion system (Wss), protein YukC
DTO10_RS02130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DTO10_RS02135	COG3935	DnaD domain protein
DTO10_RS02140	COG0017	Asparaginyl-tRNA synthetase
DTO10_RS02145	COG0436	Aminotransferase
DTO10_RS02160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DTO10_RS02160	COG1199	ATP-dependent helicase activity
DTO10_RS02165	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DTO10_RS02175	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DTO10_RS02185	COG0617	tRNA 3'-terminal CCA addition
DTO10_RS02190	COG0438	transferase activity, transferring glycosyl groups
DTO10_RS02195	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DTO10_RS02200	COG1803	Methylglyoxal synthase
DTO10_RS02205	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DTO10_RS02210	COG1694	Mazg nucleotide pyrophosphohydrolase
DTO10_RS02215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_RS02220	COG2738	Putative neutral zinc metallopeptidase
DTO10_RS02230	COG4347	Protein of unknown function (DUF1405)
DTO10_RS02255	COG5582	Belongs to the UPF0302 family
DTO10_RS02260	COG0457	Tetratricopeptide repeat
DTO10_RS02270	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DTO10_RS02275	COG0287	Prephenate dehydrogenase
DTO10_RS02280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DTO10_RS02285	COG4401	Chorismate mutase type I
DTO10_RS02290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DTO10_RS02295	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DTO10_RS02300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DTO10_RS02305	COG0105	UTP biosynthetic process
DTO10_RS02310	COG0142	geranyltranstransferase activity
DTO10_RS02315	COG2226	methyltransferase
DTO10_RS02320	COG0142	geranyltranstransferase activity
DTO10_RS02330	COG0302	gtp cyclohydrolase
DTO10_RS02335	COG0776	regulation of translation
DTO10_RS02340	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DTO10_RS02360	COG3829	transcription factor binding
DTO10_RS02360	COG3290	protein histidine kinase activity
DTO10_RS02365	COG0531	amino acid
DTO10_RS02390	COG1304	FMN binding
DTO10_RS02395	COG0539	negative regulation of cytoplasmic translation
DTO10_RS02405	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DTO10_RS02420	COG2959	enzyme of heme biosynthesis
DTO10_RS02425	COG3409	Peptidoglycan-binding domain 1 protein
DTO10_RS02425	COG3773	Cell wall hydrolase
DTO10_RS02430	COG2339	peptidase activity
DTO10_RS02440	COG0492	ferredoxin-NADP+ reductase activity
DTO10_RS02445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DTO10_RS02450	COG4862	establishment of competence for transformation
DTO10_RS02460	COG1408	metallophosphoesterase
DTO10_RS02475	COG1266	CAAX protease self-immunity
DTO10_RS02480	COG0514	ATP-dependent DNA helicase (RecQ)
DTO10_RS02485	COG4955	Helix-turn-helix domain
DTO10_RS02495	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DTO10_RS02500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DTO10_RS02510	COG1595	DNA-templated transcription, initiation
DTO10_RS02515	COG5002	protein histidine kinase activity
DTO10_RS02520	COG0745	RESPONSE REGULATOR receiver
DTO10_RS02525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DTO10_RS02530	COG1333	cytochrome c biogenesis protein
DTO10_RS02535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_RS02540	COG1187	pseudouridine synthase activity
DTO10_RS02550	COG2715	membrane protein required for spore maturation
DTO10_RS02555	COG1686	Belongs to the peptidase S11 family
DTO10_RS02570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DTO10_RS02585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DTO10_RS02600	COG1547	Domain of unknown function (DUF309)
DTO10_RS02610	COG4086	secreted protein
DTO10_RS02620	COG0697	spore germination
DTO10_RS02640	COG2252	PERMEase
DTO10_RS02650	COG2172	sigma factor antagonist activity
DTO10_RS02660	COG1686	Belongs to the peptidase S11 family
DTO10_RS02680	COG4974	Belongs to the 'phage' integrase family
DTO10_RS02690	COG0735	belongs to the Fur family
DTO10_RS02695	COG1300	Membrane
DTO10_RS02705	COG1379	DNA repair
DTO10_RS02720	COG0667	Aldo Keto reductase
DTO10_RS02725	COG1764	response to oxidative stress
DTO10_RS02730	COG1846	Transcriptional regulator
DTO10_RS02740	COG1073	alpha beta
DTO10_RS02745	COG4918	Iron-sulphur cluster biosynthesis
DTO10_RS02760	COG1309	transcriptional regulator
DTO10_RS02770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DTO10_RS02775	COG1388	LysM domain
DTO10_RS02775	COG0791	NLP P60 protein
DTO10_RS02785	COG0300	oxidoreductase activity
DTO10_RS02790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DTO10_RS02795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DTO10_RS02805	COG0789	Transcriptional regulator
DTO10_RS02810	COG1116	anion transmembrane transporter activity
DTO10_RS02810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DTO10_RS02830	COG1234	tRNA 3'-trailer cleavage
DTO10_RS02835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DTO10_RS02840	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DTO10_RS02845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DTO10_RS02850	COG2195	Cleaves the N-terminal amino acid of tripeptides
DTO10_RS02855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DTO10_RS02860	COG0346	lactoylglutathione lyase activity
DTO10_RS02865	COG1376	ErfK ybiS ycfS ynhG family protein
DTO10_RS02870	COG4129	membrane
DTO10_RS02875	COG1126	abc transporter atp-binding protein
DTO10_RS02880	COG0765	amino acid transport
DTO10_RS02885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_RS02900	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DTO10_RS02900	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DTO10_RS02910	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_RS02915	COG0022	dehydrogenase e1 component
DTO10_RS02920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DTO10_RS02925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DTO10_RS02935	COG3829	transcription factor binding
DTO10_RS02935	COG3290	protein histidine kinase activity
DTO10_RS02945	COG0584	glycerophosphoryl diester phosphodiesterase
DTO10_RS02955	COG0745	RESPONSE REGULATOR receiver
DTO10_RS02960	COG0750	zinc metalloprotease
DTO10_RS02965	COG0497	DNA recombination
DTO10_RS02970	COG1438	arginine binding
DTO10_RS02975	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DTO10_RS02980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DTO10_RS02990	COG1722	exodeoxyribonuclease VII activity
DTO10_RS02995	COG1570	exodeoxyribonuclease VII activity
DTO10_RS03000	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DTO10_RS03005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DTO10_RS03010	COG1302	Protein conserved in bacteria
DTO10_RS03015	COG0439	Biotin carboxylase
DTO10_RS03020	COG0511	ligase activity, forming carbon-carbon bonds
DTO10_RS03060	COG3854	ATPases associated with a variety of cellular activities
DTO10_RS03065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DTO10_RS03070	COG0006	proline dipeptidase activity
DTO10_RS03085	COG3872	metal-dependent enzyme
DTO10_RS03095	COG1752	Esterase of the alpha-beta hydrolase superfamily
DTO10_RS03110	COG2814	Major facilitator Superfamily
DTO10_RS03115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DTO10_RS03120	COG0095	Lipoate-protein ligase
DTO10_RS03125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DTO10_RS03135	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DTO10_RS03140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DTO10_RS03145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DTO10_RS03180	COG4537	Required for transformation and DNA binding
DTO10_RS03185	COG1459	type II secretion system
DTO10_RS03190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DTO10_RS03195	COG1393	Belongs to the ArsC family
DTO10_RS03215	COG1473	amidohydrolase
DTO10_RS03220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DTO10_RS03240	COG1368	sulfuric ester hydrolase activity
DTO10_RS03245	COG1940	carbohydrate kinase activity
DTO10_RS03260	COG0457	Tetratricopeptide repeat
DTO10_RS03260	COG0705	Rhomboid family
DTO10_RS03275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DTO10_RS03280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DTO10_RS03300	COG0704	Plays a role in the regulation of phosphate uptake
DTO10_RS03310	COG0581	inorganic phosphate transmembrane transporter activity
DTO10_RS03315	COG0573	inorganic phosphate transmembrane transporter activity
DTO10_RS03320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DTO10_RS03330	COG0477	Major facilitator Superfamily
DTO10_RS03340	COG2839	Protein conserved in bacteria
DTO10_RS03345	COG5521	maltodextrose utilization protein MalA
DTO10_RS03355	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DTO10_RS03360	COG4709	membrane
DTO10_RS03365	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
DTO10_RS03370	COG0735	belongs to the Fur family
DTO10_RS03375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DTO10_RS03380	COG1121	(ABC) transporter
DTO10_RS03390	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DTO10_RS03395	COG0513	Belongs to the DEAD box helicase family
DTO10_RS03410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DTO10_RS03415	COG2384	SAM-dependent methyltransferase
DTO10_RS03430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DTO10_RS03435	COG0358	DNA primase activity
DTO10_RS03440	COG1671	Belongs to the UPF0178 family
DTO10_RS03445	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DTO10_RS03450	COG0517	IMP dehydrogenase activity
DTO10_RS03455	COG0751	glycine-tRNA ligase activity
DTO10_RS03460	COG0752	glycyl-tRNA synthetase alpha subunit
DTO10_RS03465	COG1381	Involved in DNA repair and RecF pathway recombination
DTO10_RS03475	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DTO10_RS03480	COG0295	cytidine deaminase activity
DTO10_RS03485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DTO10_RS03490	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DTO10_RS03495	COG1480	7TM receptor with intracellular HD hydrolase
DTO10_RS03500	COG1702	phosphate starvation-inducible protein PhoH
DTO10_RS03520	COG4864	UPF0365 protein
DTO10_RS03525	COG1030	water channel activity
DTO10_RS03530	COG1610	YqeY-like protein
DTO10_RS03535	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DTO10_RS03540	COG1283	sodium-dependent phosphate transmembrane transporter activity
DTO10_RS03545	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DTO10_RS03550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DTO10_RS03555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DTO10_RS03560	COG2264	protein methyltransferase activity
DTO10_RS03565	COG0484	heat shock protein binding
DTO10_RS03570	COG0443	Heat shock 70 kDa protein
DTO10_RS03575	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DTO10_RS03580	COG1420	regulation of RNA biosynthetic process
DTO10_RS03585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DTO10_RS03600	COG0860	N-Acetylmuramoyl-L-alanine amidase
DTO10_RS03610	COG0268	Binds directly to 16S ribosomal RNA
DTO10_RS03615	COG1466	dna polymerase III delta subunit
DTO10_RS03625	COG2333	competence protein COMEC
DTO10_RS03625	COG0658	competence protein
DTO10_RS03630	COG2131	deaminase
DTO10_RS03635	COG1555	photosystem II stabilization
DTO10_RS03635	COG1596	polysaccharide export
DTO10_RS03640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DTO10_RS03645	COG2226	methyltransferase
DTO10_RS03650	COG0799	negative regulation of ribosome biogenesis
DTO10_RS03655	COG1713	HD superfamily hydrolase involved in NAD metabolism
DTO10_RS03660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DTO10_RS03665	COG1534	Rna-binding protein
DTO10_RS03675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DTO10_RS03680	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DTO10_RS03690	COG0688	phosphatidylethanolamine metabolic process
DTO10_RS03695	COG1183	phosphatidylcholine synthase activity
DTO10_RS03730	COG0626	cystathionine gamma-synthase activity
DTO10_RS03735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DTO10_RS03760	COG0768	penicillin binding
DTO10_RS03765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DTO10_RS03770	COG0572	uridine kinase
DTO10_RS03785	COG4122	O-methyltransferase activity
DTO10_RS03790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DTO10_RS03795	COG3906	Belongs to the UPF0473 family
DTO10_RS03800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DTO10_RS03815	COG0628	permease
DTO10_RS03825	COG3881	PFAM PRC-barrel domain
DTO10_RS03835	COG1704	LemA family
DTO10_RS03840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DTO10_RS03850	COG0482	sulfurtransferase activity
DTO10_RS03855	COG1104	cysteine desulfurase activity
DTO10_RS03860	COG1959	2 iron, 2 sulfur cluster binding
DTO10_RS03870	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DTO10_RS03885	COG1131	(ABC) transporter
DTO10_RS03890	COG1725	Transcriptional regulator
DTO10_RS03900	COG1316	TRANSCRIPTIONal
DTO10_RS03925	COG3944	biosynthesis protein
DTO10_RS03930	COG0489	protein tyrosine kinase activity
DTO10_RS03935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DTO10_RS03940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DTO10_RS03955	COG1215	transferase activity, transferring glycosyl groups
DTO10_RS03980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DTO10_RS04000	COG0438	transferase activity, transferring glycosyl groups
DTO10_RS04000	COG0297	glycogen (starch) synthase activity
DTO10_RS04020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DTO10_RS04030	COG4464	protein tyrosine phosphatase activity
DTO10_RS04035	COG0489	protein tyrosine kinase activity
DTO10_RS04040	COG3944	biosynthesis protein
DTO10_RS04065	COG2814	Major facilitator Superfamily
DTO10_RS04095	COG0411	ABC transporter
DTO10_RS04120	COG0411	ABC transporter
DTO10_RS04140	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DTO10_RS04165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DTO10_RS04170	COG0124	histidyl-tRNA synthetase
DTO10_RS04175	COG4991	sh3 domain protein
DTO10_RS04175	COG0860	N-Acetylmuramoyl-L-alanine amidase
DTO10_RS04175	COG3103	Sh3 type 3 domain protein
DTO10_RS04180	COG1490	D-aminoacyl-tRNA deacylase activity
DTO10_RS04185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DTO10_RS04190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DTO10_RS04195	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DTO10_RS04195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DTO10_RS04200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DTO10_RS04200	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DTO10_RS04210	COG2244	polysaccharide biosynthetic process
DTO10_RS04215	COG2323	membrane
DTO10_RS04225	COG1862	Preprotein translocase
DTO10_RS04235	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DTO10_RS04250	COG0632	four-way junction helicase activity
DTO10_RS04295	COG1122	ATPase activity
DTO10_RS04300	COG1129	ABC transporter
DTO10_RS04305	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DTO10_RS04315	COG2188	Transcriptional regulator
DTO10_RS04335	COG0157	Belongs to the NadC ModD family
DTO10_RS04340	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DTO10_RS04345	COG1104	cysteine desulfurase activity
DTO10_RS04350	COG1827	regulation of RNA biosynthetic process
DTO10_RS04355	COG0077	Prephenate dehydratase
DTO10_RS04360	COG4492	Belongs to the UPF0735 family
DTO10_RS04365	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DTO10_RS04370	COG3290	protein histidine kinase activity
DTO10_RS04380	COG2868	ribosomal protein
DTO10_RS04385	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DTO10_RS04390	COG1530	ribonuclease E activity
DTO10_RS04395	COG1994	Peptidase M50
DTO10_RS04400	COG0739	heme binding
DTO10_RS04405	COG1098	S1 RNA binding domain
DTO10_RS04410	COG2894	cell division
DTO10_RS04425	COG1792	Involved in formation and maintenance of cell shape
DTO10_RS04430	COG1077	Cell shape determining protein MreB Mrl
DTO10_RS04435	COG2003	Belongs to the UPF0758 family
DTO10_RS04440	COG0424	maF-like protein
DTO10_RS04450	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DTO10_RS04455	COG0285	dihydrofolate synthase activity
DTO10_RS04460	COG0189	ligase activity
DTO10_RS04470	COG0525	valine-tRNA ligase activity
DTO10_RS04480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DTO10_RS04485	COG1388	LysM domain
DTO10_RS04485	COG1388	LysM domain
DTO10_RS04490	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DTO10_RS04495	COG0113	porphobilinogen synthase activity
DTO10_RS04505	COG0181	hydroxymethylbilane synthase activity
DTO10_RS04510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DTO10_RS04525	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DTO10_RS04530	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DTO10_RS04535	COG0470	DNA polymerase III
DTO10_RS04535	COG1067	ATP-dependent peptidase activity
DTO10_RS04545	COG0544	peptidyl-prolyl cis-trans isomerase activity
DTO10_RS04555	COG0066	3-isopropylmalate dehydratase activity
DTO10_RS04560	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DTO10_RS04570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DTO10_RS04575	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DTO10_RS04580	COG0440	acetolactate synthase activity
DTO10_RS04585	COG0028	Belongs to the TPP enzyme family
DTO10_RS04595	COG0772	Belongs to the SEDS family
DTO10_RS04655	COG0622	Phosphoesterase
DTO10_RS04660	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DTO10_RS04680	COG5401	PFAM Sporulation and spore germination
DTO10_RS04695	COG1846	Transcriptional regulator
DTO10_RS04700	COG2197	response regulator
DTO10_RS04705	COG0824	Thioesterase
DTO10_RS04735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DTO10_RS04740	COG1053	succinate dehydrogenase
DTO10_RS04745	COG2009	succinate dehydrogenase
DTO10_RS04750	COG1719	4-vinyl reductase, 4VR
DTO10_RS04765	COG3118	belongs to the thioredoxin family
DTO10_RS04770	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DTO10_RS04775	COG2086	electron transfer activity
DTO10_RS04780	COG1024	Enoyl-CoA hydratase
DTO10_RS04785	COG1309	transcriptional regulator
DTO10_RS04790	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS04800	COG3766	membrane
DTO10_RS04805	COG1193	negative regulation of DNA recombination
DTO10_RS04810	COG1796	DNA polymerase
DTO10_RS04810	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DTO10_RS04815	COG1286	toxin biosynthetic process
DTO10_RS04820	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DTO10_RS04825	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DTO10_RS04835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DTO10_RS04835	COG0072	phenylalanine-tRNA ligase activity
DTO10_RS04840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DTO10_RS04845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DTO10_RS04870	COG0247	lactate metabolic process
DTO10_RS04875	COG0277	FAD linked oxidase domain protein
DTO10_RS04880	COG3835	regulator
DTO10_RS04885	COG1620	l-lactate permease
DTO10_RS04890	COG2186	Transcriptional regulator
DTO10_RS04895	COG0247	lactate metabolic process
DTO10_RS04900	COG1139	Iron-sulfur cluster binding protein
DTO10_RS04905	COG1556	Lactate utilization protein
DTO10_RS04910	COG1363	Peptidase, m42
DTO10_RS04930	COG3326	Membrane
DTO10_RS04935	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DTO10_RS04945	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DTO10_RS04955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DTO10_RS04965	COG1484	DNA-dependent DNA replication
DTO10_RS04970	COG3611	Membrane attachment protein
DTO10_RS04975	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DTO10_RS04980	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DTO10_RS04985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DTO10_RS04995	COG1971	Probably functions as a manganese efflux pump
DTO10_RS05000	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DTO10_RS05005	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DTO10_RS05005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DTO10_RS05010	COG0330	HflC and HflK could
DTO10_RS05015	COG0330	HflC and HflK could
DTO10_RS05020	COG5002	protein histidine kinase activity
DTO10_RS05025	COG0745	RESPONSE REGULATOR receiver
DTO10_RS05035	COG0538	isocitrate dehydrogenase activity
DTO10_RS05040	COG0372	Belongs to the citrate synthase family
DTO10_RS05045	COG2707	UPF0756 membrane protein
DTO10_RS05050	COG0628	permease
DTO10_RS05055	COG2224	Isocitrate lyase
DTO10_RS05060	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DTO10_RS05075	COG0205	6-phosphofructokinase activity
DTO10_RS05080	COG0825	malonyl-CoA metabolic process
DTO10_RS05085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DTO10_RS05090	COG2186	Transcriptional regulator
DTO10_RS05095	COG0281	malic enzyme
DTO10_RS05100	COG0587	DNA-directed DNA polymerase activity
DTO10_RS05115	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DTO10_RS05125	COG4109	DRTGG domain
DTO10_RS05135	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DTO10_RS05140	COG0006	proline dipeptidase activity
DTO10_RS05145	COG0589	response to stress
DTO10_RS05150	COG0165	Argininosuccinate lyase
DTO10_RS05155	COG0137	argininosuccinate synthase activity
DTO10_RS05165	COG0521	Mo-molybdopterin cofactor biosynthetic process
DTO10_RS05170	COG2217	Heavy metal translocating P-type atpase
DTO10_RS05175	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DTO10_RS05180	COG0827	DNA restriction-modification system
DTO10_RS05185	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DTO10_RS05190	COG3874	Sporulation protein YtfJ
DTO10_RS05200	COG1714	RDD family
DTO10_RS05205	COG0616	signal peptide processing
DTO10_RS05210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DTO10_RS05215	COG0084	hydrolase, TatD family'
DTO10_RS05220	COG1116	anion transmembrane transporter activity
DTO10_RS05225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DTO10_RS05235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DTO10_RS05245	COG2962	Rard protein
DTO10_RS05250	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DTO10_RS05255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DTO10_RS05265	COG0301	tRNA thio-modification
DTO10_RS05270	COG1104	cysteine desulfurase activity
DTO10_RS05275	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DTO10_RS05280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DTO10_RS05290	COG1956	GAF domain-containing protein
DTO10_RS05295	COG2203	Gaf domain
DTO10_RS05295	COG2199	diguanylate cyclase activity
DTO10_RS05300	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DTO10_RS05315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DTO10_RS05320	COG0454	-acetyltransferase
DTO10_RS05325	COG0517	IMP dehydrogenase activity
DTO10_RS05330	COG0123	including yeast histone deacetylase and acetoin utilization protein
DTO10_RS05335	COG1609	Transcriptional regulator
DTO10_RS05340	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DTO10_RS05340	COG1605	Chorismate mutase
DTO10_RS05350	COG3118	belongs to the thioredoxin family
DTO10_RS05355	COG4980	gas vesicle protein
DTO10_RS05365	COG2309	aminopeptidase activity
DTO10_RS05370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DTO10_RS05375	COG1674	ftsk spoiiie
DTO10_RS05380	COG1473	amidohydrolase
DTO10_RS05385	COG4848	Belongs to the UPF0354 family
DTO10_RS05390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_RS05405	COG2207	Transcriptional regulator
DTO10_RS05405	COG3708	Transcriptional regulator
DTO10_RS05410	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
DTO10_RS05415	COG1363	Peptidase, m42
DTO10_RS05425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DTO10_RS05430	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DTO10_RS05440	COG0510	thiamine kinase activity
DTO10_RS05445	COG1597	lipid kinase activity
DTO10_RS05465	COG1914	H( )-stimulated, divalent metal cation uptake system
DTO10_RS05470	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DTO10_RS05475	COG1122	ATPase activity
DTO10_RS05480	COG1122	ATPase activity
DTO10_RS05485	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS05490	COG0183	Belongs to the thiolase family
DTO10_RS05495	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS05500	COG1268	BioY protein
DTO10_RS05510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_RS05515	COG0534	Mate efflux family protein
DTO10_RS05525	COG0586	Pfam SNARE associated Golgi protein
DTO10_RS05560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DTO10_RS05560	COG1587	Uroporphyrinogen-III synthase
DTO10_RS05565	COG1587	Uroporphyrinogen-III synthase
DTO10_RS05570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DTO10_RS05580	COG0697	spore germination
DTO10_RS05585	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DTO10_RS05590	COG0124	histidyl-tRNA synthetase
DTO10_RS05600	COG0701	Predicted permease
DTO10_RS05630	COG2824	Alkylphosphonate utilization operon protein PhnA
DTO10_RS05635	COG0745	RESPONSE REGULATOR receiver
DTO10_RS05640	COG0642	Histidine kinase
DTO10_RS05645	COG1136	(ABC) transporter
DTO10_RS05650	COG0577	efflux transmembrane transporter activity
DTO10_RS05675	COG1349	DNA-binding transcription factor activity
DTO10_RS05680	COG1187	pseudouridine synthase activity
DTO10_RS05685	COG2244	polysaccharide biosynthetic process
DTO10_RS05690	COG2081	HI0933 family
DTO10_RS05710	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS05720	COG0473	3-isopropylmalate dehydrogenase activity
DTO10_RS05725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DTO10_RS05730	COG1902	pentaerythritol trinitrate reductase activity
DTO10_RS05740	COG0656	L-ascorbic acid biosynthetic process
DTO10_RS05745	COG2814	Major facilitator Superfamily
DTO10_RS05750	COG1733	regulation of RNA biosynthetic process
DTO10_RS05765	COG1309	transcriptional regulator
DTO10_RS05780	COG1647	Serine aminopeptidase, S33
DTO10_RS05785	COG1695	Transcriptional regulator
DTO10_RS05805	COG1309	transcriptional regulator
DTO10_RS05820	COG0720	synthase
DTO10_RS05830	COG0840	transmembrane signaling receptor activity
DTO10_RS05860	COG4195	phage-related replication protein
DTO10_RS05865	COG0791	NLP P60 protein
DTO10_RS05870	COG1595	DNA-templated transcription, initiation
DTO10_RS05880	COG1733	regulation of RNA biosynthetic process
DTO10_RS05890	COG2318	DinB family
DTO10_RS05900	COG0456	acetyltransferase
DTO10_RS05905	COG2002	toxin-antitoxin pair type II binding
DTO10_RS05910	COG0697	spore germination
DTO10_RS05915	COG2076	Multidrug Resistance protein
DTO10_RS05920	COG2076	Multidrug Resistance protein
DTO10_RS05930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DTO10_RS05940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DTO10_RS05950	COG0697	spore germination
DTO10_RS05955	COG0586	Pfam SNARE associated Golgi protein
DTO10_RS05960	COG0671	phosphoesterase, PA-phosphatase related
DTO10_RS05965	COG2226	methyltransferase
DTO10_RS05980	COG0583	DNA-binding transcription factor activity
DTO10_RS05985	COG2807	transmembrane transport
DTO10_RS05995	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DTO10_RS06005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DTO10_RS06010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DTO10_RS06015	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS06020	COG3829	transcription factor binding
DTO10_RS06030	COG2514	catechol 2,3-dioxygenase activity
DTO10_RS06035	COG2259	Doxx family
DTO10_RS06040	COG1668	transmembrane transport
DTO10_RS06045	COG4152	abc transporter atp-binding protein
DTO10_RS06055	COG0534	Mate efflux family protein
DTO10_RS06060	COG4608	Belongs to the ABC transporter superfamily
DTO10_RS06065	COG0444	Belongs to the ABC transporter superfamily
DTO10_RS06090	COG1126	abc transporter atp-binding protein
DTO10_RS06105	COG1309	transcriptional regulator
DTO10_RS06110	COG0246	Mannitol dehydrogenase
DTO10_RS06115	COG3711	transcriptional antiterminator
DTO10_RS06120	COG2213	PTS system mannitol-specific
DTO10_RS06120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DTO10_RS06125	COG2851	Citrate transporter
DTO10_RS06130	COG4565	transcriptional regulatory protein
DTO10_RS06135	COG3290	protein histidine kinase activity
DTO10_RS06150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DTO10_RS06165	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS06170	COG2169	Transcriptional regulator
DTO10_RS06175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DTO10_RS06185	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DTO10_RS06205	COG0346	lactoylglutathione lyase activity
DTO10_RS06220	COG0697	spore germination
DTO10_RS06245	COG1823	symporter activity
DTO10_RS06255	COG1113	amino acid transport
DTO10_RS06265	COG0785	Cytochrome C biogenesis protein
DTO10_RS06285	COG2197	response regulator
DTO10_RS06290	COG4585	Histidine kinase
DTO10_RS06310	COG1309	transcriptional regulator
DTO10_RS06315	COG3844	kynureninase activity
DTO10_RS06320	COG1113	amino acid transport
DTO10_RS06325	COG3483	tryptophan 2,3-dioxygenase activity
DTO10_RS06330	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DTO10_RS06335	COG1280	lysine exporter protein (LysE YggA)
DTO10_RS06350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DTO10_RS06370	COG0583	DNA-binding transcription factor activity
DTO10_RS06375	COG1511	domain protein
DTO10_RS06380	COG2814	Major facilitator Superfamily
DTO10_RS06385	COG1309	transcriptional regulator
DTO10_RS06405	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DTO10_RS06410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DTO10_RS06420	COG0833	amino acid
DTO10_RS06430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_RS06435	COG0183	Belongs to the thiolase family
DTO10_RS06440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DTO10_RS06445	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DTO10_RS06450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DTO10_RS06455	COG1141	Ferredoxin
DTO10_RS06470	COG1509	lysine 2,3-aminomutase activity
DTO10_RS06475	COG3829	transcription factor binding
DTO10_RS06495	COG3011	Protein conserved in bacteria
DTO10_RS06540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DTO10_RS06565	COG4989	oxidoreductase activity
DTO10_RS06570	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_RS06660	COG5444	nuclease activity
DTO10_RS06670	COG0477	Major facilitator Superfamily
DTO10_RS06705	COG3973	AAA domain
DTO10_RS06720	COG0579	oxidoreductase
DTO10_RS06725	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS06735	COG2610	gluconate transmembrane transporter activity
DTO10_RS06740	COG0583	DNA-binding transcription factor activity
DTO10_RS06780	COG0346	lactoylglutathione lyase activity
DTO10_RS06785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DTO10_RS06790	COG2814	Major facilitator Superfamily
DTO10_RS06795	COG4154	Belongs to the RbsD FucU family
DTO10_RS06800	COG0179	Fumarylacetoacetate (FAA) hydrolase
DTO10_RS06805	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS06810	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS06845	COG4319	ketosteroid isomerase
DTO10_RS06870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DTO10_RS06875	COG2318	DinB family
DTO10_RS06890	COG1114	Component of the transport system for branched-chain amino acids
DTO10_RS06895	COG1113	amino acid transport
DTO10_RS06900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DTO10_RS06905	COG0156	8-amino-7-oxononanoate synthase activity
DTO10_RS06915	COG1280	lysine exporter protein (LysE YggA)
DTO10_RS06930	COG1694	Mazg nucleotide pyrophosphohydrolase
DTO10_RS06945	COG1396	sequence-specific DNA binding
DTO10_RS06985	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DTO10_RS06990	COG0251	oxidation-reduction process
DTO10_RS06995	COG0833	amino acid
DTO10_RS07005	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DTO10_RS07015	COG0446	pyridine nucleotide-disulphide oxidoreductase
DTO10_RS07030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_RS07040	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
DTO10_RS07045	COG0640	Transcriptional regulator
DTO10_RS07050	COG2801	Transposase and inactivated derivatives
DTO10_RS07060	COG2323	membrane
DTO10_RS07070	COG2261	transglycosylase associated protein
DTO10_RS07080	COG0574	Belongs to the PEP-utilizing enzyme family
DTO10_RS07080	COG3848	Pyruvate phosphate dikinase
DTO10_RS07135	COG1595	DNA-templated transcription, initiation
DTO10_RS07165	COG1846	Transcriptional regulator
DTO10_RS07170	COG0778	Nitroreductase
DTO10_RS07195	COG0531	amino acid
DTO10_RS07200	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DTO10_RS07220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_RS07225	COG2602	Beta-lactamase
DTO10_RS07230	COG2197	response regulator
DTO10_RS07235	COG3239	Fatty acid desaturase
DTO10_RS07240	COG1027	Aspartate ammonia-lyase
DTO10_RS07245	COG0252	asparaginase activity
DTO10_RS07250	COG1396	sequence-specific DNA binding
DTO10_RS07255	COG1120	ATPase activity
DTO10_RS07260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_RS07265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_RS07270	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DTO10_RS07275	COG0561	phosphatase activity
DTO10_RS07305	COG1335	isochorismatase
DTO10_RS07325	COG0477	Major facilitator Superfamily
DTO10_RS07330	COG1309	transcriptional regulator
DTO10_RS07340	COG4122	O-methyltransferase activity
DTO10_RS07350	COG1966	Carbon starvation protein
DTO10_RS07355	COG3279	Response regulator of the LytR AlgR family
DTO10_RS07360	COG3275	phosphorelay sensor kinase activity
DTO10_RS07365	COG0583	DNA-binding transcription factor activity
DTO10_RS07370	COG0697	spore germination
DTO10_RS07380	COG1193	negative regulation of DNA recombination
DTO10_RS07385	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DTO10_RS07390	COG3842	ATPase activity
DTO10_RS07395	COG1176	ABC-type spermidine putrescine transport system, permease component I
DTO10_RS07400	COG1176	ABC-type spermidine putrescine transport system, permease component I
DTO10_RS07430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DTO10_RS07435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_RS07465	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS07475	COG2233	PERMEase
DTO10_RS07485	COG0402	S-adenosylhomocysteine deaminase activity
DTO10_RS07490	COG0402	S-adenosylhomocysteine deaminase activity
DTO10_RS07495	COG0402	S-adenosylhomocysteine deaminase activity
DTO10_RS07500	COG0747	negative chemotaxis
DTO10_RS07505	COG0402	S-adenosylhomocysteine deaminase activity
DTO10_RS07510	COG0402	S-adenosylhomocysteine deaminase activity
DTO10_RS07515	COG0747	negative chemotaxis
DTO10_RS07530	COG0444	Belongs to the ABC transporter superfamily
DTO10_RS07535	COG4608	Belongs to the ABC transporter superfamily
DTO10_RS07540	COG2972	Histidine kinase
DTO10_RS07545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DTO10_RS07545	COG2207	Transcriptional regulator
DTO10_RS07555	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DTO10_RS07565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DTO10_RS07615	COG0778	Nitroreductase
DTO10_RS07665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DTO10_RS07670	COG0697	spore germination
DTO10_RS07680	COG1366	Belongs to the anti-sigma-factor antagonist family
DTO10_RS07695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DTO10_RS07700	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DTO10_RS07710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DTO10_RS07720	COG1609	Transcriptional regulator
DTO10_RS07725	COG2318	DinB family
DTO10_RS07735	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DTO10_RS07735	COG0456	acetyltransferase
DTO10_RS07760	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DTO10_RS07765	COG1131	(ABC) transporter
DTO10_RS07790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DTO10_RS07795	COG3583	domain protein
DTO10_RS07795	COG3584	3D domain protein
DTO10_RS07825	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DTO10_RS07830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DTO10_RS07840	COG0384	phenazine biosynthesis protein PhzF
DTO10_RS07855	COG1595	DNA-templated transcription, initiation
DTO10_RS07865	COG2195	Cleaves the N-terminal amino acid of tripeptides
DTO10_RS07895	COG1231	oxidoreductase activity
DTO10_RS07905	COG0697	spore germination
DTO10_RS07910	COG0531	amino acid
DTO10_RS07925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DTO10_RS07930	COG0569	domain protein
DTO10_RS07940	COG1366	Belongs to the anti-sigma-factor antagonist family
DTO10_RS07945	COG2890	protein-(glutamine-N5) methyltransferase activity
DTO10_RS07955	COG2226	methyltransferase
DTO10_RS07975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DTO10_RS07980	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DTO10_RS07980	COG0463	Glycosyl transferase, family 2
DTO10_RS07985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DTO10_RS07990	COG2910	NAD(P)H-binding
DTO10_RS07995	COG1959	2 iron, 2 sulfur cluster binding
DTO10_RS08000	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DTO10_RS08005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DTO10_RS08010	COG1959	2 iron, 2 sulfur cluster binding
DTO10_RS08015	COG4193	domain, Protein
DTO10_RS08020	COG2112	serine threonine protein kinase
DTO10_RS08030	COG3832	glyoxalase III activity
DTO10_RS08035	COG0640	Transcriptional regulator
DTO10_RS08040	COG1511	domain protein
DTO10_RS08045	COG1959	2 iron, 2 sulfur cluster binding
DTO10_RS08050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_RS08065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DTO10_RS08080	COG0346	lactoylglutathione lyase activity
DTO10_RS08100	COG1846	Transcriptional regulator
DTO10_RS08105	COG2814	Major facilitator Superfamily
DTO10_RS08120	COG1131	(ABC) transporter
DTO10_RS08140	COG1609	Transcriptional regulator
DTO10_RS08145	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DTO10_RS08145	COG0456	acetyltransferase
DTO10_RS08165	COG0586	Pfam SNARE associated Golgi protein
DTO10_RS08170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DTO10_RS08180	COG0726	polysaccharide deacetylase
DTO10_RS08185	COG5002	protein histidine kinase activity
DTO10_RS08185	COG3850	Histidine kinase
DTO10_RS08190	COG0745	RESPONSE REGULATOR receiver
DTO10_RS08205	COG0725	ABC transporter, periplasmic molybdate-binding protein
DTO10_RS08210	COG1910	domain protein
DTO10_RS08235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DTO10_RS08240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DTO10_RS08265	COG3104	oligopeptide transport
DTO10_RS08280	COG1595	DNA-templated transcription, initiation
DTO10_RS08285	COG0726	polysaccharide deacetylase
DTO10_RS08305	COG4302	ethanolamine ammonia-lyase activity
DTO10_RS08310	COG4303	Ethanolamine ammonia lyase large subunit
DTO10_RS08355	COG4548	von Willebrand factor, type A
DTO10_RS08360	COG0714	Associated with various cellular activities
DTO10_RS08365	COG1114	Component of the transport system for branched-chain amino acids
DTO10_RS08370	COG0110	maltose O-acetyltransferase activity
DTO10_RS08375	COG0702	epimerase
DTO10_RS08380	COG5566	PFAM Mor transcription activator
DTO10_RS08390	COG0493	'glutamate synthase
DTO10_RS08395	COG0070	glutamate synthase
DTO10_RS08395	COG0069	glutamate synthase activity
DTO10_RS08395	COG0067	glutamate synthase
DTO10_RS08400	COG0583	DNA-binding transcription factor activity
DTO10_RS08405	COG5577	PFAM Coat F domain
DTO10_RS08415	COG1404	Belongs to the peptidase S8 family
DTO10_RS08420	COG0495	leucyl-tRNA aminoacylation
DTO10_RS08435	COG1242	4 iron, 4 sulfur cluster binding
DTO10_RS08440	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DTO10_RS08450	COG2267	carboxylic ester hydrolase activity
DTO10_RS08455	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DTO10_RS08460	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DTO10_RS08495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DTO10_RS08500	COG0840	transmembrane signaling receptor activity
DTO10_RS08530	COG1683	Conserved Protein
DTO10_RS08540	COG1506	peptidase
DTO10_RS08545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DTO10_RS08550	COG1116	anion transmembrane transporter activity
DTO10_RS08555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DTO10_RS08575	COG0783	Belongs to the Dps family
DTO10_RS08585	COG1854	S-ribosylhomocysteine lyase activity
DTO10_RS08590	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DTO10_RS08595	COG0803	Belongs to the bacterial solute-binding protein 9 family
DTO10_RS08595	COG3443	Belongs to the bacterial solute-binding protein 9 family
DTO10_RS08600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DTO10_RS08605	COG3290	protein histidine kinase activity
DTO10_RS08610	COG4565	transcriptional regulatory protein
DTO10_RS08615	COG4948	Mandelate Racemase Muconate Lactonizing
DTO10_RS08620	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS08625	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DTO10_RS08635	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DTO10_RS08640	COG1169	isochorismate synthase
DTO10_RS08645	COG1575	Belongs to the MenA family. Type 1 subfamily
DTO10_RS08650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DTO10_RS08775	COG0697	spore germination
DTO10_RS08780	COG1285	pathogenesis
DTO10_RS08795	COG0506	proline dehydrogenase activity
DTO10_RS08800	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS08805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_RS08810	COG2508	Transcriptional regulator
DTO10_RS08820	COG1309	transcriptional regulator
DTO10_RS08825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DTO10_RS08840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DTO10_RS08865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DTO10_RS08870	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DTO10_RS08880	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DTO10_RS08900	COG0833	amino acid
DTO10_RS08920	COG1472	Belongs to the glycosyl hydrolase 3 family
DTO10_RS08935	COG1378	Sugar-specific transcriptional regulator TrmB
DTO10_RS08950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DTO10_RS08955	COG0604	alcohol dehydrogenase
DTO10_RS08960	COG4191	Histidine kinase
DTO10_RS08965	COG3773	Cell wall hydrolase
DTO10_RS08970	COG3906	Belongs to the UPF0473 family
DTO10_RS08975	COG0346	lactoylglutathione lyase activity
DTO10_RS08990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DTO10_RS08995	COG0523	cobalamin synthesis protein
DTO10_RS09000	COG0322	excinuclease ABC activity
DTO10_RS09015	COG1785	Belongs to the alkaline phosphatase family
DTO10_RS09025	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DTO10_RS09030	COG0196	riboflavin kinase activity
DTO10_RS09040	COG0753	catalase activity
DTO10_RS09050	COG1950	PFAM Membrane protein of
DTO10_RS09055	COG0640	Transcriptional regulator
DTO10_RS09060	COG2814	Major facilitator Superfamily
DTO10_RS09065	COG2356	endonuclease I
DTO10_RS09070	COG1113	amino acid transport
DTO10_RS09080	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DTO10_RS09095	COG0697	spore germination
DTO10_RS09100	COG0737	Belongs to the 5'-nucleotidase family
DTO10_RS09105	COG2318	DinB family
DTO10_RS09110	COG0456	acetyltransferase
DTO10_RS09120	COG1191	sigma factor activity
DTO10_RS09150	COG2814	Major facilitator Superfamily
DTO10_RS09155	COG0531	amino acid
DTO10_RS09160	COG1968	undecaprenyl-diphosphatase activity
DTO10_RS09165	COG0584	glycerophosphoryl diester phosphodiesterase
DTO10_RS09175	COG3858	chitin binding
DTO10_RS09175	COG1388	LysM domain
DTO10_RS09185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DTO10_RS09200	COG1979	alcohol dehydrogenase
DTO10_RS09205	COG2155	Conserved Protein
DTO10_RS09210	COG1098	S1 RNA binding domain
DTO10_RS09220	COG0436	Aminotransferase
DTO10_RS09225	COG1522	sequence-specific DNA binding
DTO10_RS09230	COG2267	carboxylic ester hydrolase activity
DTO10_RS09240	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DTO10_RS09245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DTO10_RS09255	COG0456	acetyltransferase
DTO10_RS09265	COG1309	transcriptional regulator
DTO10_RS09275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DTO10_RS09285	COG5018	Exonuclease
DTO10_RS09290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DTO10_RS09295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DTO10_RS09300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DTO10_RS09300	COG2111	Na H antiporter
DTO10_RS09305	COG2111	Na H antiporter
DTO10_RS09310	COG1006	Multisubunit Na H antiporter MnhC subunit
DTO10_RS09315	COG0651	ATP synthesis coupled electron transport
DTO10_RS09320	COG1863	multisubunit Na H antiporter MnhE subunit
DTO10_RS09325	COG2212	antiporter activity
DTO10_RS09340	COG2050	protein possibly involved in aromatic compounds catabolism
DTO10_RS09355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DTO10_RS09355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DTO10_RS09360	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DTO10_RS09360	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DTO10_RS09370	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DTO10_RS09375	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DTO10_RS09385	COG3584	3D domain protein
DTO10_RS09400	COG1252	NADH dehydrogenase
DTO10_RS09415	COG0316	Belongs to the HesB IscA family
DTO10_RS09420	COG4844	belongs to the
DTO10_RS09425	COG1252	NADH dehydrogenase
DTO10_RS09430	COG4837	Protein of unknown function (DUF1462)
DTO10_RS09435	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DTO10_RS09440	COG0083	homoserine kinase activity
DTO10_RS09445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DTO10_RS09450	COG0460	homoserine dehydrogenase
DTO10_RS09460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DTO10_RS09465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DTO10_RS09470	COG0647	UMP catabolic process
DTO10_RS09475	COG2445	Protein of unknown function DUF86
DTO10_RS09490	COG4470	Protein conserved in bacteria
DTO10_RS09500	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DTO10_RS09505	COG0739	heme binding
DTO10_RS09520	COG3377	Domain of unknown function (DUF1805)
DTO10_RS09525	COG0737	Belongs to the 5'-nucleotidase family
DTO10_RS09530	COG0730	response to heat
DTO10_RS09535	COG1801	Protein of unknown function DUF72
DTO10_RS09540	COG0719	Fe-S assembly protein
DTO10_RS09545	COG0822	iron-sulfur transferase activity
DTO10_RS09550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DTO10_RS09555	COG0719	Fe-S assembly protein
DTO10_RS09560	COG0396	ATPase activity
DTO10_RS09575	COG1464	Belongs to the NlpA lipoprotein family
DTO10_RS09580	COG2011	ABC-type metal ion transport system permease component
DTO10_RS09585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DTO10_RS09590	COG2873	o-acetylhomoserine
DTO10_RS09595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_RS09600	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DTO10_RS09605	COG0509	glycine decarboxylation via glycine cleavage system
DTO10_RS09610	COG1393	Belongs to the ArsC family
DTO10_RS09615	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS09620	COG0183	Belongs to the thiolase family
DTO10_RS09625	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_RS09625	COG1024	Enoyl-CoA hydratase
DTO10_RS09635	COG0506	proline dehydrogenase activity
DTO10_RS09645	COG5577	PFAM Coat F domain
DTO10_RS09650	COG0772	Belongs to the SEDS family
DTO10_RS09655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DTO10_RS09660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DTO10_RS09660	COG1321	iron dependent repressor
DTO10_RS09665	COG1121	(ABC) transporter
DTO10_RS09670	COG0803	Belongs to the bacterial solute-binding protein 9 family
DTO10_RS09680	COG1609	Transcriptional regulator
DTO10_RS09685	COG0833	amino acid
DTO10_RS09690	COG0366	Alpha amylase catalytic
DTO10_RS09730	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DTO10_RS09735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DTO10_RS09740	COG1368	sulfuric ester hydrolase activity
DTO10_RS09745	COG4607	ABC-type enterochelin transport system periplasmic component
DTO10_RS09750	COG4604	ABC transporter, ATP-binding protein
DTO10_RS09755	COG4605	iron ion homeostasis
DTO10_RS09760	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_RS09765	COG4844	belongs to the
DTO10_RS09775	COG1657	PFAM Prenyltransferase squalene oxidase
DTO10_RS09790	COG3850	Histidine kinase
DTO10_RS09790	COG5002	protein histidine kinase activity
DTO10_RS09795	COG0745	RESPONSE REGULATOR receiver
DTO10_RS09800	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DTO10_RS09805	COG2197	response regulator
DTO10_RS09810	COG4585	Histidine kinase
DTO10_RS09815	COG3239	Fatty acid desaturase
DTO10_RS09825	COG3290	protein histidine kinase activity
DTO10_RS09850	COG0583	DNA-binding transcription factor activity
DTO10_RS09855	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DTO10_RS09860	COG5609	conserved protein (DUF2294)
DTO10_RS09865	COG3383	formate dehydrogenase (NAD+) activity
DTO10_RS09870	COG2427	Protein of unknown function (DUF1641)
DTO10_RS09875	COG0489	protein tyrosine kinase activity
DTO10_RS09885	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DTO10_RS09895	COG2814	Major facilitator Superfamily
DTO10_RS09910	COG0557	exoribonuclease II activity
DTO10_RS09915	COG1647	Serine aminopeptidase, S33
DTO10_RS09920	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DTO10_RS09930	COG1876	peptidase activity
DTO10_RS09950	COG0126	phosphoglycerate kinase activity
DTO10_RS09955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DTO10_RS09970	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DTO10_RS09980	COG0740	serine-type endopeptidase activity
DTO10_RS09985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DTO10_RS09995	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DTO10_RS10000	COG1660	Displays ATPase and GTPase activities
DTO10_RS10005	COG1051	belongs to the nudix hydrolase family
DTO10_RS10010	COG0492	ferredoxin-NADP+ reductase activity
DTO10_RS10015	COG0457	Tetratricopeptide repeat
DTO10_RS10020	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DTO10_RS10020	COG0140	phosphoribosyl-ATP diphosphatase activity
DTO10_RS10025	COG0107	imidazoleglycerol-phosphate synthase activity
DTO10_RS10030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DTO10_RS10035	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DTO10_RS10040	COG0131	Imidazoleglycerol-phosphate dehydratase
DTO10_RS10045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DTO10_RS10050	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DTO10_RS10055	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DTO10_RS10065	COG3764	Sortase (surface protein transpeptidase)
DTO10_RS10070	COG0110	maltose O-acetyltransferase activity
DTO10_RS10075	COG0546	phosphoglycolate phosphatase activity
DTO10_RS10080	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DTO10_RS10100	COG3595	metallopeptidase activity
DTO10_RS10105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DTO10_RS10110	COG0556	nucleotide-excision repair
DTO10_RS10115	COG4897	Protein conserved in bacteria
DTO10_RS10120	COG0753	catalase activity
DTO10_RS10130	COG2353	YceI-like domain
DTO10_RS10135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_RS10140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_RS10145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DTO10_RS10150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DTO10_RS10155	COG0793	Belongs to the peptidase S41A family
DTO10_RS10155	COG3409	Peptidoglycan-binding domain 1 protein
DTO10_RS10160	COG0791	NLP P60 protein
DTO10_RS10160	COG3883	PFAM NLP P60 protein
DTO10_RS10165	COG2177	Part of the ABC transporter FtsEX involved in
DTO10_RS10170	COG2884	Cell division ATP-binding protein ftsE
DTO10_RS10180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_RS10190	COG0653	protein targeting
DTO10_RS10195	COG1396	sequence-specific DNA binding
DTO10_RS10210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DTO10_RS10220	COG1516	flagellar protein fliS
DTO10_RS10225	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DTO10_RS10230	COG1334	flagellar protein FlaG
DTO10_RS10235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DTO10_RS10240	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DTO10_RS10245	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DTO10_RS10255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DTO10_RS10260	COG1256	bacterial-type flagellum assembly
DTO10_RS10260	COG4786	Flagellar basal body rod
DTO10_RS10285	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DTO10_RS10290	COG1307	EDD domain protein, DegV family
DTO10_RS10295	COG2197	response regulator
DTO10_RS10300	COG4585	Histidine kinase
DTO10_RS10305	COG1739	Uncharacterized protein family UPF0029
DTO10_RS10310	COG1316	TRANSCRIPTIONal
DTO10_RS10315	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DTO10_RS10315	COG1215	transferase activity, transferring glycosyl groups
DTO10_RS10320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DTO10_RS10325	COG0438	transferase activity, transferring glycosyl groups
DTO10_RS10330	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DTO10_RS10340	COG0728	peptidoglycan biosynthetic process
DTO10_RS10345	COG0438	transferase activity, transferring glycosyl groups
DTO10_RS10355	COG1682	transport, permease protein
DTO10_RS10360	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DTO10_RS10365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DTO10_RS10370	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DTO10_RS10375	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DTO10_RS10385	COG1388	LysM domain
DTO10_RS10385	COG0791	NLP P60 protein
DTO10_RS10400	COG1368	sulfuric ester hydrolase activity
DTO10_RS10410	COG0653	protein targeting
DTO10_RS10415	COG1785	Belongs to the alkaline phosphatase family
DTO10_RS10420	COG2247	cell wall binding repeat
DTO10_RS10420	COG2385	sporulation resulting in formation of a cellular spore
DTO10_RS10425	COG2356	endonuclease I
DTO10_RS10430	COG0737	Belongs to the 5'-nucleotidase family
DTO10_RS10435	COG0768	penicillin binding
DTO10_RS10465	COG4715	Zinc finger, swim domain protein
DTO10_RS10480	COG1279	arginine transmembrane transporter activity
DTO10_RS10485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_RS10510	COG0747	negative chemotaxis
DTO10_RS10515	COG4608	Belongs to the ABC transporter superfamily
DTO10_RS10520	COG0444	Belongs to the ABC transporter superfamily
DTO10_RS10525	COG0629	single-stranded DNA binding
DTO10_RS10550	COG4786	Flagellar basal body rod
DTO10_RS10555	COG4786	Flagellar basal body rod
DTO10_RS10560	COG1077	Cell shape determining protein MreB Mrl
DTO10_RS10565	COG1609	Transcriptional regulator
DTO10_RS10570	COG0739	heme binding
DTO10_RS10580	COG2385	sporulation resulting in formation of a cellular spore
DTO10_RS10595	COG4836	Membrane
DTO10_RS10600	COG1007	ATP synthesis coupled electron transport
DTO10_RS10605	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DTO10_RS10610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DTO10_RS10615	COG0713	ATP synthesis coupled electron transport
DTO10_RS10620	COG0839	Belongs to the complex I subunit 6 family
DTO10_RS10625	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DTO10_RS10645	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DTO10_RS10650	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DTO10_RS10660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DTO10_RS10675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DTO10_RS10685	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DTO10_RS10690	COG0356	it plays a direct role in the translocation of protons across the membrane
DTO10_RS10705	COG1404	Belongs to the peptidase S8 family
DTO10_RS10710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DTO10_RS10715	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DTO10_RS10730	COG0698	ribose 5-phosphate isomerase
DTO10_RS10735	COG0840	transmembrane signaling receptor activity
DTO10_RS10745	COG1971	Probably functions as a manganese efflux pump
DTO10_RS10750	COG0009	L-threonylcarbamoyladenylate synthase
DTO10_RS10760	COG2890	protein-(glutamine-N5) methyltransferase activity
DTO10_RS10765	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DTO10_RS10780	COG0832	Belongs to the urease beta subunit family
DTO10_RS10785	COG0804	urea catabolic process
DTO10_RS10790	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DTO10_RS10795	COG0830	nickel cation binding
DTO10_RS10800	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DTO10_RS10805	COG0829	nickel cation binding
DTO10_RS10825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DTO10_RS10830	COG0601	transmembrane transport
DTO10_RS10840	COG1435	thymidine kinase activity
DTO10_RS10850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DTO10_RS10855	COG1494	fructose-1,6-bisphosphatase
DTO10_RS10865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DTO10_RS10875	COG2204	response regulator
DTO10_RS10880	COG4821	SIS domain
DTO10_RS10885	COG0504	CTP synthase activity
DTO10_RS10890	COG3343	RNA polymerase activity
DTO10_RS10895	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DTO10_RS10895	COG1703	isobutyryl-CoA mutase activity
DTO10_RS10895	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DTO10_RS10905	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS10910	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS10915	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_RS10920	COG0183	Belongs to the thiolase family
DTO10_RS10925	COG0247	lactate metabolic process
DTO10_RS10925	COG2181	nitrate reductase activity
DTO10_RS10930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DTO10_RS10940	COG0018	arginyl-trna synthetase
DTO10_RS10950	COG0010	Belongs to the arginase family
DTO10_RS10955	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DTO10_RS10960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DTO10_RS10970	COG1994	Peptidase M50
DTO10_RS10980	COG3465	dGTPase activity
DTO10_RS10985	COG1078	dGTPase activity
DTO10_RS10990	COG4844	belongs to the
DTO10_RS11000	COG0095	Lipoate-protein ligase
DTO10_RS11005	COG0280	phosphate acetyltransferase
DTO10_RS11020	COG2363	Small membrane protein
DTO10_RS11035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DTO10_RS11050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DTO10_RS11055	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DTO10_RS11060	COG0314	molybdopterin synthase activity
DTO10_RS11065	COG0746	molybdenum cofactor guanylyltransferase activity
DTO10_RS11070	COG0351	phosphomethylpyrimidine kinase
DTO10_RS11075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DTO10_RS11085	COG2814	Major facilitator Superfamily
DTO10_RS11090	COG1846	Transcriptional regulator
DTO10_RS11100	COG0561	phosphatase activity
DTO10_RS11110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DTO10_RS11135	COG2096	Adenosyltransferase
DTO10_RS11150	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DTO10_RS11160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DTO10_RS11165	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DTO10_RS11170	COG1120	ATPase activity
DTO10_RS11175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_RS11180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DTO10_RS11185	COG0726	polysaccharide deacetylase
DTO10_RS11190	COG1120	ATPase activity
DTO10_RS11220	COG0778	Nitroreductase
DTO10_RS11225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DTO10_RS11225	COG0551	DNA topoisomerase type I activity
DTO10_RS11230	COG0488	(ABC) transporter
DTO10_RS11255	COG2252	PERMEase
DTO10_RS11280	COG0723	plastoquinol--plastocyanin reductase activity
DTO10_RS11280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DTO10_RS11285	COG4895	conserved protein (DUF2196)
DTO10_RS11295	COG0788	formyltetrahydrofolate deformylase activity
DTO10_RS11310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_RS11325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DTO10_RS11335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DTO10_RS11335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DTO10_RS11340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DTO10_RS11350	COG5002	protein histidine kinase activity
DTO10_RS11355	COG0745	RESPONSE REGULATOR receiver
DTO10_RS11360	COG0577	efflux transmembrane transporter activity
DTO10_RS11365	COG1136	(ABC) transporter
DTO10_RS11375	COG3162	membrane
DTO10_RS11380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_RS11395	COG2267	carboxylic ester hydrolase activity
DTO10_RS11400	COG1301	dicarboxylic acid transport
DTO10_RS11410	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DTO10_RS11420	COG0583	DNA-binding transcription factor activity
DTO10_RS11425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DTO10_RS11430	COG1879	ABC-type sugar transport system periplasmic component
DTO10_RS11435	COG1172	Belongs to the binding-protein-dependent transport system permease family
DTO10_RS11440	COG1129	ABC transporter
DTO10_RS11445	COG1869	D-ribose catabolic process
DTO10_RS11450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DTO10_RS11455	COG1609	Transcriptional regulator
DTO10_RS11475	COG4264	IucA IucC family
DTO10_RS11480	COG0076	glutamate decarboxylase activity
DTO10_RS11505	COG2195	Cleaves the N-terminal amino acid of tripeptides
DTO10_RS11520	COG0583	DNA-binding transcription factor activity
DTO10_RS11535	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DTO10_RS11540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DTO10_RS11550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DTO10_RS11555	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DTO10_RS11560	COG4853	Protein conserved in bacteria
DTO10_RS11570	COG5002	protein histidine kinase activity
DTO10_RS11575	COG0745	RESPONSE REGULATOR receiver
DTO10_RS11610	COG0305	Participates in initiation and elongation during chromosome replication
DTO10_RS11615	COG0359	binds to the 23S rRNA
DTO10_RS11620	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DTO10_RS11630	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DTO10_RS11635	COG0629	single-stranded DNA binding
DTO10_RS11640	COG0360	Binds together with S18 to 16S ribosomal RNA
DTO10_RS11645	COG0012	GTP binding
DTO10_RS11650	COG4481	Protein conserved in bacteria
DTO10_RS11655	COG0668	transmembrane transport
DTO10_RS11665	COG1811	Na channel or pump
DTO10_RS11670	COG1475	DNA binding
DTO10_RS11675	COG1192	Involved in chromosome partitioning
DTO10_RS11680	COG1475	DNA binding
DTO10_RS11685	COG0357	Ribosomal RNA small subunit methyltransferase G
DTO10_RS11690	COG0445	tRNA wobble uridine modification
DTO10_RS11700	COG1847	R3H domain protein
DTO10_RS11705	COG0706	membrane insertase activity
DTO10_RS11710	COG0594	ribonuclease P activity
DTO10_RS11720	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DTO10_RS11725	COG0592	DNA-directed DNA polymerase activity
DTO10_RS11730	COG2501	S4 domain
DTO10_RS11735	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DTO10_RS11745	COG0187	DNA topoisomerase II activity
DTO10_RS11750	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DTO10_RS11755	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DTO10_RS11790	COG0517	IMP dehydrogenase activity
DTO10_RS11790	COG0516	GMP reductase activity
DTO10_RS11810	COG1428	Deoxynucleoside kinase
DTO10_RS11815	COG1428	Deoxynucleoside kinase
DTO10_RS11820	COG1335	isochorismatase
DTO10_RS11825	COG0590	tRNA wobble adenosine to inosine editing
DTO10_RS11835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DTO10_RS11840	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DTO10_RS11845	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DTO10_RS11890	COG1982	Orn Lys Arg decarboxylase major
DTO10_RS11895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DTO10_RS11900	COG3870	Protein conserved in bacteria
DTO10_RS11905	COG1728	Protein conserved in bacteria
DTO10_RS11910	COG0470	DNA polymerase III
DTO10_RS11915	COG1774	PSP1 C-terminal conserved region
DTO10_RS11920	COG4467	Involved in initiation control of chromosome replication
DTO10_RS11925	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DTO10_RS11935	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DTO10_RS11940	COG2002	toxin-antitoxin pair type II binding
DTO10_RS11950	COG0084	hydrolase, TatD family'
DTO10_RS11955	COG3584	3D domain protein
DTO10_RS11955	COG3583	domain protein
DTO10_RS11975	COG4466	Protein conserved in bacteria
DTO10_RS11990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DTO10_RS11995	COG0251	oxidation-reduction process
DTO10_RS12000	COG2088	sporulation resulting in formation of a cellular spore
DTO10_RS12005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DTO10_RS12015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DTO10_RS12020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DTO10_RS12025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DTO10_RS12030	COG1116	anion transmembrane transporter activity
DTO10_RS12035	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DTO10_RS12050	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DTO10_RS12055	COG2002	toxin-antitoxin pair type II binding
DTO10_RS12060	COG2244	polysaccharide biosynthetic process
DTO10_RS12065	COG3956	TIGRFAM MazG family protein
DTO10_RS12070	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DTO10_RS12085	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DTO10_RS12090	COG1098	S1 RNA binding domain
DTO10_RS12105	COG2208	phosphoserine phosphatase activity
DTO10_RS12110	COG2304	oxidoreductase activity
DTO10_RS12115	COG0515	serine threonine protein kinase
DTO10_RS12120	COG0037	tRNA processing
DTO10_RS12130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DTO10_RS12135	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DTO10_RS12140	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DTO10_RS12145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DTO10_RS12150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DTO10_RS12155	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DTO10_RS12160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DTO10_RS12165	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DTO10_RS12170	COG1396	sequence-specific DNA binding
DTO10_RS12175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DTO10_RS12180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DTO10_RS12205	COG3880	PFAM UvrB UvrC protein
DTO10_RS12210	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DTO10_RS12215	COG0542	response to heat
DTO10_RS12220	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DTO10_RS12230	COG4956	integral membrane protein (PIN domain superfamily)
DTO10_RS12240	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DTO10_RS12245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DTO10_RS12250	COG1045	serine acetyltransferase
DTO10_RS12255	COG0215	cysteine-tRNA ligase activity
DTO10_RS12265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DTO10_RS12270	COG3688	RNA-binding protein containing a PIN domain
DTO10_RS12280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DTO10_RS12285	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DTO10_RS12290	COG0250	Participates in transcription elongation, termination and antitermination
DTO10_RS12295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DTO10_RS12300	COG0081	regulation of translation
DTO10_RS12310	COG0222	ribosome binding
DTO10_RS12315	COG2813	Specifically methylates the guanine in position
DTO10_RS12320	COG0085	RNA polymerase activity
DTO10_RS12325	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DTO10_RS12330	COG1358	cellular component organization or biogenesis
DTO10_RS12335	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DTO10_RS12340	COG0049	tRNA binding
DTO10_RS12345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DTO10_RS12350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DTO10_RS12355	COG0051	transcription antitermination factor activity, RNA binding
DTO10_RS12360	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DTO10_RS12365	COG0088	Forms part of the polypeptide exit tunnel
DTO10_RS12375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DTO10_RS12380	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DTO10_RS12385	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DTO10_RS12390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DTO10_RS12395	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DTO10_RS12400	COG0255	Belongs to the universal ribosomal protein uL29 family
DTO10_RS12405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DTO10_RS12410	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DTO10_RS12415	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DTO10_RS12425	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DTO10_RS12430	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DTO10_RS12435	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DTO10_RS12440	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DTO10_RS12445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DTO10_RS12450	COG1841	ribosomal large subunit assembly
DTO10_RS12460	COG0201	protein transport
DTO10_RS12465	COG0563	adenylate kinase activity
DTO10_RS12470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DTO10_RS12475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DTO10_RS12480	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DTO10_RS12485	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DTO10_RS12490	COG0202	RNA polymerase activity
DTO10_RS12495	COG0203	ribosomal protein L17
DTO10_RS12500	COG1122	ATPase activity
DTO10_RS12505	COG1122	ATPase activity
DTO10_RS12510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DTO10_RS12520	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DTO10_RS12535	COG0383	alpha-mannosidase activity
DTO10_RS12550	COG5578	integral membrane protein
DTO10_RS12560	COG2972	Histidine kinase
DTO10_RS12565	COG4753	response regulator
DTO10_RS12565	COG2207	Transcriptional regulator
DTO10_RS12570	COG4209	transmembrane transport
DTO10_RS12575	COG0395	ABC-type sugar transport system, permease component
DTO10_RS12585	COG2723	6-phospho-beta-galactosidase activity
DTO10_RS12590	COG1940	carbohydrate kinase activity
DTO10_RS12595	COG1940	carbohydrate kinase activity
DTO10_RS12600	COG1482	cell wall glycoprotein biosynthetic process
DTO10_RS12615	COG0860	N-Acetylmuramoyl-L-alanine amidase
DTO10_RS12620	COG0489	protein tyrosine kinase activity
DTO10_RS12630	COG2194	sulfuric ester hydrolase activity
DTO10_RS12635	COG0726	polysaccharide deacetylase
DTO10_RS12715	COG1595	DNA-templated transcription, initiation
DTO10_RS12720	COG5662	AntiSigma factor
DTO10_RS12725	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DTO10_RS12730	COG4856	YbbR-like protein
DTO10_RS12735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DTO10_RS12740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DTO10_RS12745	COG5646	InterPro IPR014922
DTO10_RS12760	COG0840	transmembrane signaling receptor activity
DTO10_RS12765	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS12775	COG1278	Cold shock
DTO10_RS12795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DTO10_RS12800	COG0493	'glutamate synthase
DTO10_RS12805	COG0167	dihydroorotate dehydrogenase activity
DTO10_RS12825	COG3835	regulator
DTO10_RS12865	COG1597	lipid kinase activity
DTO10_RS12870	COG0025	NhaP-type Na H and K H
DTO10_RS12890	COG3842	ATPase activity
DTO10_RS12895	COG1176	ABC-type spermidine putrescine transport system, permease component I
DTO10_RS12905	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DTO10_RS12910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DTO10_RS12920	COG4821	SIS domain
DTO10_RS12925	COG2188	Transcriptional regulator
DTO10_RS12930	COG0363	glucosamine-6-phosphate deaminase activity
DTO10_RS12935	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DTO10_RS12940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DTO10_RS12940	COG2190	(PTS) system
DTO10_RS12940	COG1263	PTS System
DTO10_RS12945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DTO10_RS12960	COG2814	Major facilitator Superfamily
DTO10_RS12965	COG1846	Transcriptional regulator
DTO10_RS12970	COG2822	iron ion transport
DTO10_RS12975	COG2837	iron assimilation
DTO10_RS12980	COG0672	)-iron permease
DTO10_RS12990	COG0789	Transcriptional regulator
DTO10_RS12995	COG1253	flavin adenine dinucleotide binding
DTO10_RS13000	COG2205	protein histidine kinase activity
DTO10_RS13000	COG0784	Response regulator, receiver
DTO10_RS13000	COG2198	Histidine kinase
DTO10_RS13005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DTO10_RS13010	COG2208	phosphoserine phosphatase activity
DTO10_RS13065	COG4974	Belongs to the 'phage' integrase family
DTO10_RS13070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DTO10_RS13115	COG1181	Belongs to the D-alanine--D-alanine ligase family
DTO10_RS13120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DTO10_RS13125	COG2208	phosphoserine phosphatase activity
DTO10_RS13130	COG0513	Belongs to the DEAD box helicase family
DTO10_RS13135	COG3402	PFAM membrane-flanked domain
DTO10_RS13140	COG3428	Bacterial PH domain
DTO10_RS13145	COG0705	Rhomboid family
DTO10_RS13150	COG0736	holo-[acyl-carrier-protein] synthase activity
DTO10_RS13155	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DTO10_RS13165	COG0864	Transcriptional regulator
DTO10_RS13170	COG2337	Toxic component of a toxin-antitoxin (TA) module
DTO10_RS13175	COG1366	Belongs to the anti-sigma-factor antagonist family
DTO10_RS13180	COG1366	Belongs to the anti-sigma-factor antagonist family
DTO10_RS13185	COG2172	sigma factor antagonist activity
DTO10_RS13190	COG2208	phosphoserine phosphatase activity
DTO10_RS13195	COG1366	Belongs to the anti-sigma-factor antagonist family
DTO10_RS13200	COG2172	sigma factor antagonist activity
DTO10_RS13205	COG1191	sigma factor activity
DTO10_RS13210	COG2208	phosphoserine phosphatase activity
DTO10_RS13215	COG2183	response to ionizing radiation
DTO10_RS13305	COG0802	atpase or kinase
DTO10_RS13310	COG1214	PFAM Peptidase M22, glycoprotease
DTO10_RS13315	COG0456	acetyltransferase
DTO10_RS13325	COG0488	(ABC) transporter
DTO10_RS13330	COG0315	cyclic pyranopterin monophosphate synthase activity
DTO10_RS13335	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DTO10_RS13345	COG1266	CAAX protease self-immunity
DTO10_RS13355	COG0459	protein refolding
DTO10_RS13380	COG0747	negative chemotaxis
DTO10_RS13385	COG0601	transmembrane transport
DTO10_RS13395	COG0444	Belongs to the ABC transporter superfamily
DTO10_RS13400	COG4608	Belongs to the ABC transporter superfamily
DTO10_RS13405	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DTO10_RS13415	COG1940	carbohydrate kinase activity
DTO10_RS13420	COG3142	Participates in the control of copper homeostasis
DTO10_RS13440	COG1136	(ABC) transporter
DTO10_RS13455	COG1070	Carbohydrate kinase
DTO10_RS13465	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DTO10_RS13475	COG4585	Histidine kinase
DTO10_RS13480	COG2197	response regulator
DTO10_RS13485	COG1404	Belongs to the peptidase S8 family
DTO10_RS13500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DTO10_RS13505	COG2011	ABC-type metal ion transport system permease component
DTO10_RS13510	COG1464	Belongs to the NlpA lipoprotein family
DTO10_RS13520	COG1686	Belongs to the peptidase S11 family
DTO10_RS13525	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS13530	COG0028	Belongs to the TPP enzyme family
DTO10_RS13535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DTO10_RS13540	COG1288	antiporter activity
DTO10_RS13570	COG1228	amidohydrolase
DTO10_RS13580	COG4175	Glycine betaine
DTO10_RS13580	COG0517	IMP dehydrogenase activity
DTO10_RS13585	COG2113	Glycine betaine
DTO10_RS13600	COG4842	Belongs to the WXG100 family
DTO10_RS13605	COG5417	Belongs to the EsaB family
DTO10_RS13610	COG4499	WXG100 protein secretion system (Wss), protein YukC
DTO10_RS13615	COG1674	ftsk spoiiie
DTO10_RS13620	COG1511	domain protein
DTO10_RS13630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DTO10_RS13640	COG0714	Associated with various cellular activities
DTO10_RS13645	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DTO10_RS13650	COG1305	Transglutaminase-like
DTO10_RS13655	COG0519	Catalyzes the synthesis of GMP from XMP
DTO10_RS13655	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DTO10_RS13660	COG2252	PERMEase
DTO10_RS13665	COG3711	transcriptional antiterminator
DTO10_RS13670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DTO10_RS13670	COG2190	(PTS) system
DTO10_RS13670	COG1263	PTS System
DTO10_RS13705	COG2814	Major facilitator Superfamily
DTO10_RS13715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DTO10_RS13720	COG2814	Major facilitator Superfamily
DTO10_RS13730	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DTO10_RS13755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DTO10_RS13760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DTO10_RS13765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DTO10_RS13775	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DTO10_RS13780	COG0047	phosphoribosylformylglycinamidine synthase activity
DTO10_RS13790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DTO10_RS13800	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DTO10_RS13810	COG0151	Belongs to the GarS family
DTO10_RS13825	COG1470	cell adhesion involved in biofilm formation
DTO10_RS13830	COG4496	protein, YerC YecD
DTO10_RS13835	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DTO10_RS13840	COG0210	DNA helicase
DTO10_RS13845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DTO10_RS13850	COG4851	CamS sex pheromone cAM373 precursor
DTO10_RS13855	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS13860	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DTO10_RS13865	COG0154	amidase activity
DTO10_RS13870	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DTO10_RS13875	COG1595	DNA-templated transcription, initiation
DTO10_RS13895	COG1597	lipid kinase activity
DTO10_RS13900	COG0456	acetyltransferase
DTO10_RS13915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_RS13920	COG2323	membrane
DTO10_RS13935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DTO10_RS13960	COG0004	ammonium transporteR
DTO10_RS13985	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
DTO10_RS13990	COG3853	Toxic anion resistance protein (TelA)
DTO10_RS13995	COG0778	Nitroreductase
DTO10_RS14005	COG1404	Belongs to the peptidase S8 family
DTO10_RS14010	COG4549	nuclear export factor GLE1
DTO10_RS14015	COG1276	copper resistance
DTO10_RS14015	COG2372	response to copper ion
DTO10_RS14020	COG2514	catechol 2,3-dioxygenase activity
DTO10_RS14030	COG5002	protein histidine kinase activity
DTO10_RS14035	COG0398	Pfam SNARE associated Golgi protein
DTO10_RS14040	COG4708	membrane
DTO10_RS14045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DTO10_RS14065	COG2204	response regulator
DTO10_RS14070	COG5002	protein histidine kinase activity
DTO10_RS14080	COG2234	aminopeptidase activity
DTO10_RS14095	COG5444	nuclease activity
DTO10_RS14115	COG2733	membrane
DTO10_RS14130	COG5002	protein histidine kinase activity
DTO10_RS14130	COG3850	Histidine kinase
DTO10_RS14135	COG0577	efflux transmembrane transporter activity
DTO10_RS14140	COG1136	(ABC) transporter
DTO10_RS14150	COG0596	Alpha beta hydrolase
DTO10_RS14160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_RS14185	COG1609	Transcriptional regulator
DTO10_RS14195	COG0673	inositol 2-dehydrogenase activity
DTO10_RS14200	COG0673	inositol 2-dehydrogenase activity
DTO10_RS14210	COG1187	pseudouridine synthase activity
DTO10_RS14215	COG0697	spore germination
DTO10_RS14225	COG0667	Aldo Keto reductase
DTO10_RS14230	COG1114	Component of the transport system for branched-chain amino acids
DTO10_RS14245	COG1129	ABC transporter
DTO10_RS14250	COG1172	Belongs to the binding-protein-dependent transport system permease family
DTO10_RS14265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DTO10_RS14275	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DTO10_RS14285	COG1845	cytochrome c oxidase, subunit III
DTO10_RS14310	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DTO10_RS14315	COG0527	aspartate kinase activity
DTO10_RS14320	COG1668	transmembrane transport
DTO10_RS14330	COG0778	Nitroreductase
DTO10_RS14335	COG1132	(ABC) transporter
DTO10_RS14340	COG1132	(ABC) transporter
DTO10_RS14345	COG1966	Carbon starvation protein
DTO10_RS14350	COG2879	small protein
DTO10_RS14355	COG0004	ammonium transporteR
DTO10_RS14360	COG0347	Belongs to the P(II) protein family
DTO10_RS14370	COG3279	Response regulator of the LytR AlgR family
DTO10_RS14375	COG0427	acetyl-CoA hydrolase
DTO10_RS14380	COG0628	permease
DTO10_RS14385	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS14390	COG1301	dicarboxylic acid transport
DTO10_RS14395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DTO10_RS14400	COG1263	PTS System
DTO10_RS14400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DTO10_RS14405	COG0366	Alpha amylase catalytic
DTO10_RS14410	COG2188	Transcriptional regulator
DTO10_RS14415	COG3583	domain protein
DTO10_RS14415	COG3584	3D domain protein
DTO10_RS14420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_RS14425	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
DTO10_RS14440	COG2027	D-alanyl-D-alanine carboxypeptidase
DTO10_RS14445	COG0546	phosphoglycolate phosphatase activity
DTO10_RS14455	COG1335	isochorismatase
DTO10_RS14460	COG0778	Nitroreductase
DTO10_RS14465	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DTO10_RS14475	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS14480	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS14485	COG0243	molybdopterin cofactor binding
DTO10_RS14490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_RS14495	COG5002	protein histidine kinase activity
DTO10_RS14500	COG0513	Belongs to the DEAD box helicase family
DTO10_RS14515	COG0626	cystathionine gamma-synthase activity
DTO10_RS14525	COG0307	riboflavin synthase, alpha
DTO10_RS14530	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DTO10_RS14530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DTO10_RS14540	COG2404	hydrolase activity, acting on ester bonds
DTO10_RS14545	COG1295	ribonuclease BN
DTO10_RS14555	COG0475	glutathione-regulated potassium exporter activity
DTO10_RS14560	COG0490	domain, Protein
DTO10_RS14565	COG0582	viral genome integration into host DNA
DTO10_RS14570	COG1077	Cell shape determining protein MreB Mrl
DTO10_RS14575	COG3180	Ammonia monooxygenase
DTO10_RS14580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DTO10_RS14585	COG1360	Flagellar Motor Protein
DTO10_RS14595	COG0693	protein deglycase activity
DTO10_RS14600	COG0024	Methionine aminopeptidase
DTO10_RS14610	COG1763	Mo-molybdopterin cofactor biosynthetic process
DTO10_RS14615	COG0303	'Molybdopterin
DTO10_RS14620	COG4840	Belongs to the UPF0435 family
DTO10_RS14630	COG1295	ribonuclease BN
DTO10_RS14635	COG2217	Heavy metal translocating P-type atpase
DTO10_RS14640	COG0477	Major facilitator Superfamily
DTO10_RS14645	COG0387	Pfam Sodium calcium exchanger
DTO10_RS14655	COG0535	radical SAM domain protein
DTO10_RS14680	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DTO10_RS14685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DTO10_RS14690	COG4807	Protein conserved in bacteria
DTO10_RS14695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_RS14700	COG0765	amino acid transport
DTO10_RS14705	COG1126	abc transporter atp-binding protein
DTO10_RS14720	COG1840	ABC-type Fe3 transport system, periplasmic component
DTO10_RS14735	COG0165	Argininosuccinate lyase
DTO10_RS14745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_RS14755	COG1113	amino acid transport
DTO10_RS14765	COG1113	amino acid transport
DTO10_RS14770	COG0531	amino acid
DTO10_RS14820	COG1131	(ABC) transporter
DTO10_RS14825	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DTO10_RS14835	COG2235	arginine
DTO10_RS14845	COG4187	Peptidase family M20/M25/M40
DTO10_RS14855	COG0833	amino acid
DTO10_RS14860	COG3069	C4-dicarboxylate transmembrane transporter activity
DTO10_RS14890	COG1136	(ABC) transporter
DTO10_RS14895	COG0577	efflux transmembrane transporter activity
DTO10_RS14905	COG2205	protein histidine kinase activity
DTO10_RS14910	COG0745	RESPONSE REGULATOR receiver
DTO10_RS14925	COG1126	abc transporter atp-binding protein
DTO10_RS14930	COG0765	amino acid transport
DTO10_RS14935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_RS14945	COG1090	epimerase
DTO10_RS14950	COG0436	Aminotransferase
DTO10_RS14980	COG1388	LysM domain
DTO10_RS14980	COG0791	NLP P60 protein
DTO10_RS14995	COG1695	Transcriptional regulator
DTO10_RS15010	COG0385	Bile acid
DTO10_RS15020	COG2814	Major facilitator Superfamily
DTO10_RS15040	COG0166	Belongs to the GPI family
DTO10_RS15045	COG0628	permease
DTO10_RS15055	COG0765	amino acid transport
DTO10_RS15070	COG0583	DNA-binding transcription factor activity
DTO10_RS15090	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS15095	COG0183	Belongs to the thiolase family
DTO10_RS15115	COG1090	epimerase
DTO10_RS15140	COG1988	membrane-bound metal-dependent
DTO10_RS15145	COG1194	a g-specific adenine glycosylase
DTO10_RS15160	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS15175	COG3557	Belongs to the UPF0374 family
DTO10_RS15180	COG1132	(ABC) transporter
DTO10_RS15195	COG0655	NAD(P)H dehydrogenase (quinone) activity
DTO10_RS15200	COG2814	Major facilitator Superfamily
DTO10_RS15205	COG1566	PFAM secretion protein HlyD family protein
DTO10_RS15210	COG1846	Transcriptional regulator
DTO10_RS15215	COG4129	membrane
DTO10_RS15220	COG0067	glutamate synthase
DTO10_RS15220	COG0069	glutamate synthase activity
DTO10_RS15220	COG0070	glutamate synthase
DTO10_RS15225	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DTO10_RS15235	COG4555	ABC transporter
DTO10_RS15250	COG1607	acyl-coa hydrolase
DTO10_RS15255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DTO10_RS15265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DTO10_RS15285	COG0735	belongs to the Fur family
DTO10_RS15390	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DTO10_RS15490	COG4974	Belongs to the 'phage' integrase family
DTO10_RS15570	COG2066	Belongs to the glutaminase family
DTO10_RS15580	COG0582	viral genome integration into host DNA
DTO10_RS15595	COG2814	Major facilitator Superfamily
DTO10_RS15605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DTO10_RS15615	COG5002	protein histidine kinase activity
DTO10_RS15620	COG0584	glycerophosphoryl diester phosphodiesterase
DTO10_RS15640	COG1011	Hydrolase
DTO10_RS15645	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DTO10_RS15650	COG5577	PFAM Coat F domain
DTO10_RS15675	COG1388	LysM domain
DTO10_RS15680	COG4129	membrane
DTO10_RS15710	COG0745	RESPONSE REGULATOR receiver
DTO10_RS15745	COG0179	Fumarylacetoacetate (FAA) hydrolase
DTO10_RS15755	COG1247	-acetyltransferase
DTO10_RS15765	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DTO10_RS15790	COG0346	lactoylglutathione lyase activity
DTO10_RS15810	COG0393	Putative heavy-metal-binding
DTO10_RS15835	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
DTO10_RS15840	COG3048	D-serine ammonia-lyase activity
DTO10_RS15850	COG3773	Cell wall hydrolase
DTO10_RS15890	COG3773	Cell wall hydrolase
DTO10_RS15905	COG0456	acetyltransferase
DTO10_RS15905	COG1846	Transcriptional regulator
DTO10_RS15920	COG0697	spore germination
DTO10_RS15925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_RS15935	COG0114	fumarate hydratase activity
DTO10_RS15940	COG0697	spore germination
DTO10_RS15955	COG0531	amino acid
DTO10_RS15960	COG0531	amino acid
DTO10_RS15975	COG2610	gluconate transmembrane transporter activity
DTO10_RS15990	COG1802	Transcriptional regulator
DTO10_RS15995	COG2084	Dehydrogenase
DTO10_RS16010	COG2610	gluconate transmembrane transporter activity
DTO10_RS16030	COG1141	Ferredoxin
DTO10_RS16035	COG4638	Rieske (2fe-2S)
DTO10_RS16040	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS16045	COG0473	3-isopropylmalate dehydrogenase activity
DTO10_RS16050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DTO10_RS16055	COG1011	Hydrolase
DTO10_RS16060	COG3290	protein histidine kinase activity
DTO10_RS16060	COG3829	transcription factor binding
DTO10_RS16080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DTO10_RS16090	COG1984	allophanate hydrolase subunit 2
DTO10_RS16100	COG0439	Biotin carboxylase
DTO10_RS16105	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DTO10_RS16110	COG3829	transcription factor binding
DTO10_RS16110	COG3290	protein histidine kinase activity
DTO10_RS16125	COG1309	transcriptional regulator
DTO10_RS16130	COG0477	Major facilitator Superfamily
DTO10_RS16140	COG0640	Transcriptional regulator
DTO10_RS16150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_RS16155	COG0697	spore germination
DTO10_RS16175	COG1473	amidohydrolase
DTO10_RS16190	COG0586	Pfam SNARE associated Golgi protein
DTO10_RS16200	COG1473	amidohydrolase
DTO10_RS16210	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DTO10_RS16240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DTO10_RS16245	COG1280	lysine exporter protein (LysE YggA)
DTO10_RS16280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_RS16290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DTO10_RS16295	COG0805	protein transport
DTO10_RS16305	COG2205	protein histidine kinase activity
DTO10_RS16310	COG2723	6-phospho-beta-galactosidase activity
DTO10_RS16315	COG2188	Transcriptional regulator
DTO10_RS16320	COG2814	Major facilitator Superfamily
DTO10_RS16340	COG2076	Multidrug Resistance protein
DTO10_RS16345	COG2076	Multidrug Resistance protein
DTO10_RS16360	COG1132	(ABC) transporter
DTO10_RS16365	COG2130	NADP-dependent
DTO10_RS16370	COG1289	transmembrane transporter activity
DTO10_RS16385	COG3382	B3 4 domain protein
DTO10_RS16390	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DTO10_RS16400	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DTO10_RS16405	COG0778	Nitroreductase
DTO10_RS16410	COG1120	ATPase activity
DTO10_RS16415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DTO10_RS16420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_RS16425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_RS16430	COG0784	Response regulator, receiver
DTO10_RS16435	COG4191	Histidine kinase
DTO10_RS16445	COG0531	amino acid
DTO10_RS16450	COG1115	amino acid carrier protein
DTO10_RS16455	COG2766	serine protein kinase
DTO10_RS16475	COG2718	Belongs to the UPF0229 family
DTO10_RS16580	COG0322	excinuclease ABC activity
DTO10_RS16620	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DTO10_RS16650	COG1702	phosphate starvation-inducible protein PhoH
DTO10_RS16660	COG0756	dUTP diphosphatase activity
DTO10_RS16670	COG3584	3D domain protein
DTO10_RS16815	COG1652	LysM domain
DTO10_RS16830	COG3628	GPW Gp25 family protein
DTO10_RS16835	COG3299	homolog of phage Mu protein gp47
DTO10_RS16880	COG1876	peptidase activity
DTO10_RS16915	COG1674	ftsk spoiiie
DTO10_RS16945	COG2807	transmembrane transport
DTO10_RS16955	COG1113	amino acid transport
DTO10_RS16995	COG0531	amino acid
DTO10_RS17025	COG0385	Bile acid
DTO10_RS17035	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DTO10_RS17050	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DTO10_RS17055	COG2068	MobA-Related Protein
DTO10_RS17060	COG2094	Belongs to the DNA glycosylase MPG family
DTO10_RS17065	COG0477	Major facilitator Superfamily
DTO10_RS17070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DTO10_RS17075	COG0277	FAD linked oxidase domain protein
DTO10_RS17080	COG0412	Dienelactone hydrolase
DTO10_RS17085	COG0686	Belongs to the AlaDH PNT family
DTO10_RS17090	COG2217	Heavy metal translocating P-type atpase
DTO10_RS17095	COG2508	Transcriptional regulator
DTO10_RS17095	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DTO10_RS17100	COG0306	phosphate transporter
DTO10_RS17105	COG1392	Phosphate transport regulator
DTO10_RS17110	COG0306	phosphate transporter
DTO10_RS17115	COG0656	L-ascorbic acid biosynthetic process
DTO10_RS17120	COG2261	transglycosylase associated protein
DTO10_RS17125	COG0564	pseudouridine synthase activity
DTO10_RS17140	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DTO10_RS17145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DTO10_RS17145	COG3153	acetyltransferase
DTO10_RS17150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DTO10_RS17160	COG0431	NADPH-dependent FMN reductase
DTO10_RS17180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DTO10_RS17190	COG1473	amidohydrolase
DTO10_RS17200	COG4948	Mandelate Racemase Muconate Lactonizing
DTO10_RS17205	COG3949	Membrane
DTO10_RS17210	COG2719	SpoVR family
DTO10_RS17215	COG2329	Antibiotic biosynthesis monooxygenase
DTO10_RS17220	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DTO10_RS17245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_RS17295	COG3655	Transcriptional regulator
DTO10_RS17310	COG0640	Transcriptional regulator
DTO10_RS17315	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DTO10_RS17320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DTO10_RS17325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DTO10_RS17330	COG0840	transmembrane signaling receptor activity
DTO10_RS17335	COG0784	Response regulator, receiver
DTO10_RS17335	COG3437	response regulator, receiver
DTO10_RS17345	COG0398	Pfam SNARE associated Golgi protein
DTO10_RS17350	COG0745	RESPONSE REGULATOR receiver
DTO10_RS17355	COG3850	Histidine kinase
DTO10_RS17355	COG5002	protein histidine kinase activity
DTO10_RS17360	COG1522	sequence-specific DNA binding
DTO10_RS17365	COG2059	Chromate
DTO10_RS17370	COG2059	Chromate
DTO10_RS17380	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DTO10_RS17395	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_RS17400	COG3162	membrane
DTO10_RS17405	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DTO10_RS17410	COG0492	ferredoxin-NADP+ reductase activity
DTO10_RS17415	COG1141	Ferredoxin
DTO10_RS17420	COG3396	Phenylacetate-CoA oxygenase
DTO10_RS17445	COG1024	Enoyl-CoA hydratase
DTO10_RS17450	COG1024	Enoyl-CoA hydratase
DTO10_RS17455	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS17460	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_RS17465	COG0183	Belongs to the thiolase family
DTO10_RS17470	COG1024	Enoyl-CoA hydratase
DTO10_RS17475	COG3327	negative regulation of DNA-templated transcription, initiation
DTO10_RS17505	COG0745	RESPONSE REGULATOR receiver
DTO10_RS17510	COG5002	protein histidine kinase activity
DTO10_RS17515	COG1393	Belongs to the ArsC family
DTO10_RS17525	COG1393	Belongs to the ArsC family
DTO10_RS17535	COG1393	Belongs to the ArsC family
DTO10_RS17545	COG4149	molybdate abc transporter
DTO10_RS17565	COG1278	Cold shock
DTO10_RS17570	COG0716	FMN binding
DTO10_RS17575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DTO10_RS17580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DTO10_RS17585	COG1227	inorganic diphosphatase activity
DTO10_RS17590	COG0659	secondary active sulfate transmembrane transporter activity
DTO10_RS17605	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS17610	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_RS17615	COG1024	Enoyl-CoA hydratase
DTO10_RS17620	COG0183	Belongs to the thiolase family
DTO10_RS17625	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS17635	COG2271	Major facilitator Superfamily
DTO10_RS17655	COG2814	Major facilitator Superfamily
DTO10_RS17660	COG2851	Citrate transporter
DTO10_RS17680	COG0456	acetyltransferase
DTO10_RS17690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_RS17710	COG1253	flavin adenine dinucleotide binding
DTO10_RS17715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_RS17725	COG0586	Pfam SNARE associated Golgi protein
DTO10_RS17730	COG1253	flavin adenine dinucleotide binding
DTO10_RS17735	COG3852	Histidine kinase
DTO10_RS17740	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DTO10_RS17745	COG0589	response to stress
DTO10_RS17750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DTO10_RS17760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DTO10_RS17775	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_RS17785	COG1113	amino acid transport
DTO10_RS17790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DTO10_RS17795	COG1522	sequence-specific DNA binding
DTO10_RS17805	COG1522	sequence-specific DNA binding
DTO10_RS17815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DTO10_RS17820	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DTO10_RS17885	COG0753	catalase activity
DTO10_RS17890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DTO10_RS17900	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS17915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DTO10_RS17920	COG0516	GMP reductase activity
DTO10_RS17920	COG0517	IMP dehydrogenase activity
DTO10_RS17940	COG1132	(ABC) transporter
DTO10_RS17945	COG1132	(ABC) transporter
DTO10_RS17950	COG0254	rRNA binding
DTO10_RS17955	COG0626	cystathionine gamma-synthase activity
DTO10_RS17960	COG0626	cystathionine gamma-synthase activity
DTO10_RS17965	COG0114	fumarate hydratase activity
DTO10_RS17975	COG3842	ATPase activity
DTO10_RS17980	COG2508	Transcriptional regulator
DTO10_RS17990	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DTO10_RS18005	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DTO10_RS18015	COG1464	Belongs to the NlpA lipoprotein family
DTO10_RS18020	COG2011	ABC-type metal ion transport system permease component
DTO10_RS18025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DTO10_RS18035	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DTO10_RS18060	COG0463	Glycosyl transferase, family 2
DTO10_RS18090	COG0189	ligase activity
DTO10_RS18095	COG0189	ligase activity
DTO10_RS18100	COG0189	ligase activity
DTO10_RS18105	COG0189	ligase activity
DTO10_RS18115	COG3679	Belongs to the UPF0342 family
DTO10_RS18120	COG0561	phosphatase activity
DTO10_RS18145	COG0832	Belongs to the urease beta subunit family
DTO10_RS18170	COG1834	amidinotransferase
DTO10_RS18175	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS18180	COG1024	Enoyl-CoA hydratase
DTO10_RS18195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DTO10_RS18200	COG0420	3'-5' exonuclease activity
DTO10_RS18205	COG4717	serine-type aminopeptidase activity
DTO10_RS18220	COG1120	ATPase activity
DTO10_RS18240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DTO10_RS18270	COG1846	Transcriptional regulator
DTO10_RS18275	COG4980	gas vesicle protein
DTO10_RS18295	COG0537	adenosine 5'-monophosphoramidase activity
DTO10_RS18300	COG1131	(ABC) transporter
DTO10_RS18305	COG4473	ABC transporter
DTO10_RS18315	COG1473	amidohydrolase
DTO10_RS18320	COG0671	phosphoesterase, PA-phosphatase related
DTO10_RS18325	COG2329	Antibiotic biosynthesis monooxygenase
DTO10_RS18330	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DTO10_RS18340	COG1309	transcriptional regulator
DTO10_RS18350	COG1234	tRNA 3'-trailer cleavage
DTO10_RS18355	COG0095	Lipoate-protein ligase
DTO10_RS18360	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS18365	COG1418	mRNA catabolic process
DTO10_RS18375	COG0501	Belongs to the peptidase M48B family
DTO10_RS18380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_RS18390	COG4903	ComK protein
DTO10_RS18400	COG2333	competence protein COMEC
DTO10_RS18400	COG0658	competence protein
DTO10_RS18410	COG0398	Pfam SNARE associated Golgi protein
DTO10_RS18420	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DTO10_RS18465	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS18475	COG2311	Membrane
DTO10_RS18490	COG0367	asparagine synthase
DTO10_RS18500	COG2182	Extracellular solute-binding protein
DTO10_RS18510	COG0366	Alpha amylase catalytic
DTO10_RS18515	COG1609	Transcriptional regulator
DTO10_RS18525	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS18530	COG1666	GTP binding
DTO10_RS18540	COG1307	EDD domain protein, DegV family
DTO10_RS18545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_RS18550	COG3729	General stress protein
DTO10_RS18560	COG0561	phosphatase activity
DTO10_RS18565	COG1073	alpha beta
DTO10_RS18570	COG2151	metal-sulfur cluster biosynthetic enzyme
DTO10_RS18575	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DTO10_RS18580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DTO10_RS18585	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DTO10_RS18590	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DTO10_RS18595	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DTO10_RS18605	COG0505	Belongs to the CarA family
DTO10_RS18615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DTO10_RS18630	COG0179	Fumarylacetoacetate (FAA) hydrolase
DTO10_RS18645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DTO10_RS18650	COG0542	response to heat
DTO10_RS18660	COG2267	carboxylic ester hydrolase activity
DTO10_RS18680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DTO10_RS18685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DTO10_RS18690	COG5504	Zn-dependent protease
DTO10_RS18700	COG0180	Tryptophanyl-tRNA synthetase
DTO10_RS18715	COG0456	acetyltransferase
DTO10_RS18720	COG1393	Belongs to the ArsC family
DTO10_RS18725	COG4862	establishment of competence for transformation
DTO10_RS18730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DTO10_RS18735	COG4469	Competence protein
DTO10_RS18740	COG1164	Oligoendopeptidase f
DTO10_RS18755	COG2346	COG2346, Truncated hemoglobins
DTO10_RS18760	COG0741	lytic transglycosylase activity
DTO10_RS18765	COG4116	CYTH
DTO10_RS18770	COG2357	RelA SpoT domain protein
DTO10_RS18780	COG0564	pseudouridine synthase activity
DTO10_RS18790	COG2239	Acts as a magnesium transporter
DTO10_RS18795	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DTO10_RS18840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DTO10_RS18860	COG0210	DNA helicase
DTO10_RS18875	COG2153	protein acetylation
DTO10_RS18880	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DTO10_RS18885	COG2382	esterase
DTO10_RS18890	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DTO10_RS18905	COG0693	protein deglycase activity
DTO10_RS18930	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DTO10_RS18935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DTO10_RS18940	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS18955	COG5337	Spore coat protein CotH
DTO10_RS18965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DTO10_RS18970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DTO10_RS18985	COG2814	Major facilitator Superfamily
DTO10_RS18990	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS18995	COG0673	inositol 2-dehydrogenase activity
DTO10_RS19005	COG1902	pentaerythritol trinitrate reductase activity
DTO10_RS19010	COG2272	Belongs to the type-B carboxylesterase lipase family
DTO10_RS19015	COG3844	kynureninase activity
DTO10_RS19020	COG1113	amino acid transport
DTO10_RS19025	COG3483	tryptophan 2,3-dioxygenase activity
DTO10_RS19030	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DTO10_RS19035	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DTO10_RS19040	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DTO10_RS19050	COG4208	sulfate ABC transporter
DTO10_RS19060	COG2239	Acts as a magnesium transporter
DTO10_RS19075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DTO10_RS19090	COG0791	NLP P60 protein
DTO10_RS19090	COG3883	PFAM NLP P60 protein
DTO10_RS19105	COG2017	converts alpha-aldose to the beta-anomer
DTO10_RS19110	COG0531	amino acid
DTO10_RS19115	COG5583	Uncharacterized small protein (DUF2292)
DTO10_RS19130	COG1278	Cold shock
DTO10_RS19140	COG2309	aminopeptidase activity
DTO10_RS19145	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS19150	COG0477	Major facilitator Superfamily
DTO10_RS19155	COG0352	thiamine-phosphate diphosphorylase activity
DTO10_RS19160	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DTO10_RS19165	COG0351	phosphomethylpyrimidine kinase
DTO10_RS19165	COG0352	thiamine-phosphate diphosphorylase activity
DTO10_RS19175	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DTO10_RS19190	COG1247	-acetyltransferase
DTO10_RS19200	COG1132	(ABC) transporter
DTO10_RS19205	COG2318	DinB family
DTO10_RS19210	COG1876	peptidase activity
DTO10_RS19215	COG1607	acyl-coa hydrolase
DTO10_RS19220	COG0670	Belongs to the BI1 family
DTO10_RS19230	COG4608	Belongs to the ABC transporter superfamily
DTO10_RS19235	COG0601	transmembrane transport
DTO10_RS19240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DTO10_RS19250	COG1363	Peptidase, m42
DTO10_RS19255	COG3871	stress protein (general stress protein 26)
DTO10_RS19265	COG0189	ligase activity
DTO10_RS19265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DTO10_RS19270	COG4412	M6 family metalloprotease domain protein
DTO10_RS19270	COG1404	Belongs to the peptidase S8 family
DTO10_RS19290	COG0584	glycerophosphoryl diester phosphodiesterase
DTO10_RS19300	COG1764	response to oxidative stress
DTO10_RS19305	COG1725	Transcriptional regulator
DTO10_RS19310	COG1131	(ABC) transporter
DTO10_RS19330	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DTO10_RS19340	COG0772	Belongs to the SEDS family
DTO10_RS19355	COG0861	Integral membrane protein TerC family
DTO10_RS19360	COG1191	sigma factor activity
DTO10_RS19375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DTO10_RS19380	COG3852	Histidine kinase
DTO10_RS19385	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS19390	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS19395	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS19400	COG1309	transcriptional regulator
DTO10_RS19405	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_RS19410	COG1024	Enoyl-CoA hydratase
DTO10_RS19425	COG2045	Belongs to the ComB family
DTO10_RS19430	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS19435	COG1024	Enoyl-CoA hydratase
DTO10_RS19455	COG3594	Acyltransferase
DTO10_RS19460	COG5002	protein histidine kinase activity
DTO10_RS19475	COG2223	nitrite transmembrane transporter activity
DTO10_RS19480	COG3852	Histidine kinase
DTO10_RS19485	COG1846	Transcriptional regulator
DTO10_RS19495	COG3949	Membrane
DTO10_RS19505	COG4873	Protein conserved in bacteria
DTO10_RS19525	COG1525	nuclease
DTO10_RS19535	COG0390	transport system, permease component
DTO10_RS19545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DTO10_RS19555	COG2084	Dehydrogenase
DTO10_RS19565	COG0436	Aminotransferase
DTO10_RS19570	COG0598	Magnesium transport protein CorA
DTO10_RS19575	COG1714	RDD family
DTO10_RS19580	COG0784	Response regulator, receiver
DTO10_RS19580	COG0835	chemotaxis
DTO10_RS19595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DTO10_RS19600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DTO10_RS19605	COG1408	metallophosphoesterase
DTO10_RS19610	COG0490	domain, Protein
DTO10_RS19610	COG0471	metal ion transport
DTO10_RS19615	COG2200	EAL domain
DTO10_RS19640	COG4703	Protein of unknown function (DUF1797)
DTO10_RS19645	COG0517	IMP dehydrogenase activity
DTO10_RS19650	COG0477	Major facilitator Superfamily
DTO10_RS19655	COG0583	DNA-binding transcription factor activity
DTO10_RS19660	COG2171	N-acyltransferase activity
DTO10_RS19665	COG1473	amidohydrolase
DTO10_RS19670	COG0569	domain protein
DTO10_RS19675	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DTO10_RS19690	COG0561	phosphatase activity
DTO10_RS19715	COG0022	dehydrogenase e1 component
DTO10_RS19720	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_RS19735	COG0726	polysaccharide deacetylase
DTO10_RS19765	COG1982	Orn Lys Arg decarboxylase major
DTO10_RS19775	COG4476	Belongs to the UPF0223 family
DTO10_RS19785	COG0512	Glutamine amidotransferase of anthranilate synthase
DTO10_RS19795	COG0134	indole-3-glycerol-phosphate synthase activity
DTO10_RS19825	COG0483	inositol monophosphate 1-phosphatase activity
DTO10_RS19855	COG4896	Protein conserved in bacteria
DTO10_RS19865	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DTO10_RS19870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DTO10_RS19875	COG4838	Belongs to the UPF0358 family
DTO10_RS19880	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DTO10_RS19885	COG1612	heme a metabolic process
DTO10_RS19890	COG0109	protoheme IX farnesyltransferase activity
DTO10_RS19915	COG3336	cytochrome c oxidase
DTO10_RS19930	COG2340	Cysteine-rich secretory protein family
DTO10_RS19955	COG3679	Belongs to the UPF0342 family
DTO10_RS19965	COG4471	UPF0298 protein
DTO10_RS19975	COG0742	ribosomal rna small subunit methyltransferase
DTO10_RS19980	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DTO10_RS19985	COG3314	Sporulation integral membrane protein YlbJ
DTO10_RS19990	COG1752	Esterase of the alpha-beta hydrolase superfamily
DTO10_RS19995	COG3480	Lon protease (S16) C-terminal proteolytic domain
DTO10_RS20000	COG1323	Belongs to the UPF0348 family
DTO10_RS20005	COG1399	metal-binding, possibly nucleic acid-binding protein
DTO10_RS20010	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DTO10_RS20015	COG1024	Enoyl-CoA hydratase
DTO10_RS20025	COG0454	-acetyltransferase
DTO10_RS20030	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DTO10_RS20040	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DTO10_RS20045	COG2001	Belongs to the MraZ family
DTO10_RS20065	COG0768	penicillin binding
DTO10_RS20075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DTO10_RS20080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DTO10_RS20085	COG0772	Belongs to the SEDS family
DTO10_RS20090	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DTO10_RS20095	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DTO10_RS20100	COG3879	Bacterial protein of unknown function (DUF881)
DTO10_RS20105	COG3879	Bacterial protein of unknown function (DUF881)
DTO10_RS20110	COG3856	small basic protein
DTO10_RS20115	COG0849	cell division
DTO10_RS20120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DTO10_RS20130	COG1191	sigma factor activity
DTO10_RS20135	COG1191	sigma factor activity
DTO10_RS20140	COG1873	PFAM PRC-barrel domain
DTO10_RS20150	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DTO10_RS20155	COG1799	cell septum assembly
DTO10_RS20160	COG0762	integral membrane protein
DTO10_RS20165	COG2302	S4 RNA-binding domain
DTO10_RS20170	COG3599	regulation of cell shape
DTO10_RS20180	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DTO10_RS20185	COG0564	pseudouridine synthase activity
DTO10_RS20190	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DTO10_RS20200	COG0540	Belongs to the ATCase OTCase family
DTO10_RS20215	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DTO10_RS20225	COG0167	dihydroorotate dehydrogenase activity
DTO10_RS20230	COG0284	orotidine-5'-phosphate decarboxylase activity
DTO10_RS20235	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DTO10_RS20245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DTO10_RS20250	COG1561	YicC-like family, N-terminal region
DTO10_RS20260	COG0194	GDP metabolic process
DTO10_RS20270	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DTO10_RS20275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DTO10_RS20285	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DTO10_RS20290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DTO10_RS20290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DTO10_RS20300	COG0631	protein serine/threonine phosphatase activity
DTO10_RS20305	COG2815	serine threonine protein kinase
DTO10_RS20305	COG0515	serine threonine protein kinase
DTO10_RS20310	COG1162	GTPase activity
DTO10_RS20315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DTO10_RS20320	COG1564	THIamine pyrophosphokinase
DTO10_RS20330	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DTO10_RS20335	COG1302	Protein conserved in bacteria
DTO10_RS20340	COG1461	Dihydroxyacetone kinase
DTO10_RS20345	COG1760	l-serine dehydratase
DTO10_RS20350	COG1760	l-serine dehydratase
DTO10_RS20355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DTO10_RS20360	COG1349	DNA-binding transcription factor activity
DTO10_RS20370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DTO10_RS20375	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS20380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DTO10_RS20385	COG0571	ribonuclease III activity
DTO10_RS20390	COG1196	nuclear chromosome segregation
DTO10_RS20395	COG0552	protein localization to endoplasmic reticulum
DTO10_RS20405	COG1131	(ABC) transporter
DTO10_RS20420	COG0714	Associated with various cellular activities
DTO10_RS20445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DTO10_RS20450	COG0228	four-way junction DNA binding
DTO10_RS20455	COG1837	Belongs to the UPF0109 family
DTO10_RS20465	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DTO10_RS20470	COG0336	Belongs to the RNA methyltransferase TrmD family
DTO10_RS20475	COG0335	large ribosomal subunit rRNA binding
DTO10_RS20485	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DTO10_RS20490	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DTO10_RS20515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DTO10_RS20525	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DTO10_RS20530	COG0758	DNA mediated transformation
DTO10_RS20535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DTO10_RS20540	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DTO10_RS20545	COG4974	Belongs to the 'phage' integrase family
DTO10_RS20555	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DTO10_RS20560	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DTO10_RS20565	COG1815	bacterial-type flagellum-dependent cell motility
DTO10_RS20570	COG1558	bacterial-type flagellum-dependent cell motility
DTO10_RS20575	COG1677	Flagellar hook-basal body complex protein FliE
DTO10_RS20580	COG1766	The M ring may be actively involved in energy transduction
DTO10_RS20585	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DTO10_RS20590	COG1317	bacterial-type flagellum organization
DTO10_RS20595	COG1157	protein secretion by the type III secretion system
DTO10_RS20600	COG2882	bacterial-type flagellum organization
DTO10_RS20615	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DTO10_RS20630	COG1582	Flagellar protein (FlbD)
DTO10_RS20635	COG1580	Controls the rotational direction of flagella during chemotaxis
DTO10_RS20640	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DTO10_RS20645	COG1776	CheC inhibitor of MCP methylation
DTO10_RS20645	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DTO10_RS20650	COG2201	protein-glutamate methylesterase activity
DTO10_RS20655	COG3190	flagellar
DTO10_RS20660	COG1338	Plays a role in the flagellum-specific transport system
DTO10_RS20665	COG1987	bacterial-type flagellum assembly
DTO10_RS20670	COG1684	flagellar biosynthetic protein fliR
DTO10_RS20675	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DTO10_RS20680	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DTO10_RS20685	COG1419	protein localization to endoplasmic reticulum
DTO10_RS20690	COG0455	bacterial-type flagellum organization
DTO10_RS20695	COG2201	protein-glutamate methylesterase activity
DTO10_RS20700	COG2201	protein-glutamate methylesterase activity
DTO10_RS20705	COG0643	Histidine kinase
DTO10_RS20705	COG2198	Histidine kinase
DTO10_RS20710	COG0835	chemotaxis
DTO10_RS20715	COG1776	CheC inhibitor of MCP methylation
DTO10_RS20720	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DTO10_RS20725	COG1191	sigma factor activity
DTO10_RS20750	COG0528	UMP kinase activity
DTO10_RS20765	COG4589	Belongs to the CDS family
DTO10_RS20770	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DTO10_RS20775	COG0750	zinc metalloprotease
DTO10_RS20785	COG2176	DNA-directed DNA polymerase activity
DTO10_RS20790	COG0779	Required for maturation of 30S ribosomal subunits
DTO10_RS20795	COG0195	Participates in both transcription termination and antitermination
DTO10_RS20800	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DTO10_RS20805	COG1358	cellular component organization or biogenesis
DTO10_RS20810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DTO10_RS20815	COG1550	Protein conserved in bacteria
DTO10_RS20820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DTO10_RS20825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DTO10_RS20830	COG0196	riboflavin kinase activity
DTO10_RS20840	COG1185	polyribonucleotide nucleotidyltransferase activity
DTO10_RS20845	COG0726	polysaccharide deacetylase
DTO10_RS20850	COG0612	Peptidase, M16
DTO10_RS20855	COG1873	PFAM PRC-barrel domain
DTO10_RS20860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DTO10_RS20865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DTO10_RS20870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DTO10_RS20875	COG0527	aspartate kinase activity
DTO10_RS20880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DTO10_RS20885	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DTO10_RS20890	COG0740	serine-type endopeptidase activity
DTO10_RS20900	COG1674	ftsk spoiiie
DTO10_RS20900	COG4980	gas vesicle protein
DTO10_RS20910	COG2188	Transcriptional regulator
DTO10_RS20935	COG0612	Peptidase, M16
DTO10_RS20940	COG0612	Peptidase, M16
DTO10_RS20945	COG0300	oxidoreductase activity
DTO10_RS20960	COG1426	Protein conserved in bacteria
DTO10_RS20965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DTO10_RS20970	COG1058	Belongs to the CinA family
DTO10_RS20970	COG1546	Belongs to the CinA family
DTO10_RS20975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DTO10_RS20985	COG1692	metallophosphoesterase
DTO10_RS20990	COG2359	stage V sporulation protein S
DTO10_RS21000	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DTO10_RS21000	COG0674	pyruvate-flavodoxin oxidoreductase activity
DTO10_RS21005	COG1013	pyruvate-flavodoxin oxidoreductase activity
DTO10_RS21020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DTO10_RS21025	COG4550	Control of competence regulator ComK, YlbF/YmcA
DTO10_RS21035	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DTO10_RS21045	COG0582	viral genome integration into host DNA
DTO10_RS21050	COG2856	Zn peptidase
DTO10_RS21085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_RS21090	COG0582	viral genome integration into host DNA
DTO10_RS21100	COG2132	Multicopper oxidase
DTO10_RS21110	COG1297	OPT oligopeptide transporter protein
DTO10_RS21120	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS21130	COG2223	nitrite transmembrane transporter activity
DTO10_RS21135	COG2188	Transcriptional regulator
DTO10_RS21140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DTO10_RS21145	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DTO10_RS21150	COG1447	Phosphotransferase system cellobiose-specific component IIA
DTO10_RS21155	COG1486	melibiose metabolic process
DTO10_RS21160	COG3394	polysaccharide catabolic process
DTO10_RS21165	COG1252	NADH dehydrogenase
DTO10_RS21175	COG0604	alcohol dehydrogenase
DTO10_RS21185	COG1396	sequence-specific DNA binding
DTO10_RS21190	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DTO10_RS21205	COG0745	RESPONSE REGULATOR receiver
DTO10_RS21210	COG5002	protein histidine kinase activity
DTO10_RS21215	COG1136	(ABC) transporter
DTO10_RS21220	COG0577	efflux transmembrane transporter activity
DTO10_RS21235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DTO10_RS21240	COG1923	regulation of RNA biosynthetic process
DTO10_RS21245	COG0464	growth
DTO10_RS21250	COG2860	membrane
DTO10_RS21255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DTO10_RS21260	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DTO10_RS21265	COG0789	Transcriptional regulator
DTO10_RS21270	COG0174	glutamine synthetase
DTO10_RS21370	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DTO10_RS21410	COG0860	N-Acetylmuramoyl-L-alanine amidase
DTO10_RS21465	COG2323	membrane
DTO10_RS21480	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DTO10_RS21525	COG1902	pentaerythritol trinitrate reductase activity
DTO10_RS21580	COG0531	amino acid
DTO10_RS21640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DTO10_RS21645	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DTO10_RS21650	COG0778	Nitroreductase
DTO10_RS21655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DTO10_RS21660	COG0716	FMN binding
DTO10_RS21680	COG0010	Belongs to the arginase family
DTO10_RS21685	COG0583	DNA-binding transcription factor activity
DTO10_RS21710	COG2720	vancomycin resistance protein
DTO10_RS21725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_RS21740	COG0583	DNA-binding transcription factor activity
DTO10_RS21780	COG0028	Belongs to the TPP enzyme family
DTO10_RS21795	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DTO10_RS21815	COG1522	sequence-specific DNA binding
DTO10_RS21820	COG0405	Gamma-glutamyltransferase
DTO10_RS21830	COG2271	Major facilitator Superfamily
DTO10_RS21840	COG0626	cystathionine gamma-synthase activity
DTO10_RS21860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_RS21865	COG0765	amino acid transport
DTO10_RS21870	COG1126	abc transporter atp-binding protein
DTO10_RS21875	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DTO10_RS21900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_RS21910	COG1051	belongs to the nudix hydrolase family
DTO10_RS21925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DTO10_RS21930	COG1388	LysM domain
DTO10_RS21935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DTO10_RS21940	COG4224	UPF0291 protein
DTO10_RS21955	COG3763	UPF0154 protein
DTO10_RS21960	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DTO10_RS21965	COG2271	Major facilitator Superfamily
DTO10_RS21970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DTO10_RS21990	COG3118	belongs to the thioredoxin family
DTO10_RS21995	COG1902	pentaerythritol trinitrate reductase activity
DTO10_RS22000	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DTO10_RS22010	COG2259	Doxx family
DTO10_RS22025	COG0785	Cytochrome C biogenesis protein
DTO10_RS22030	COG2201	protein-glutamate methylesterase activity
DTO10_RS22035	COG4846	Membrane protein involved in cytochrome C biogenesis
DTO10_RS22055	COG0419	ATPase involved in DNA repair
DTO10_RS22060	COG0071	Belongs to the small heat shock protein (HSP20) family
DTO10_RS22075	COG4187	Peptidase family M20/M25/M40
DTO10_RS22080	COG1288	antiporter activity
DTO10_RS22090	COG1024	Enoyl-CoA hydratase
DTO10_RS22105	COG1024	Enoyl-CoA hydratase
DTO10_RS22120	COG2151	metal-sulfur cluster biosynthetic enzyme
DTO10_RS22135	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_RS22140	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_RS22145	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS22165	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS22175	COG0183	Belongs to the thiolase family
DTO10_RS22180	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS22185	COG0183	Belongs to the thiolase family
DTO10_RS22225	COG0346	lactoylglutathione lyase activity
DTO10_RS22230	COG4257	antibiotic catabolic process
DTO10_RS22275	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DTO10_RS22285	COG1414	Transcriptional regulator
DTO10_RS22290	COG1414	Transcriptional regulator
DTO10_RS22295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DTO10_RS22300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DTO10_RS22305	COG0183	Belongs to the thiolase family
DTO10_RS22330	COG1414	Transcriptional regulator
DTO10_RS22340	COG0824	Thioesterase
DTO10_RS22350	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DTO10_RS22365	COG1522	sequence-specific DNA binding
DTO10_RS22385	COG1473	amidohydrolase
DTO10_RS22430	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS22440	COG2986	histidine ammonia-lyase
DTO10_RS22445	COG0833	amino acid
DTO10_RS22450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DTO10_RS22535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_RS22540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DTO10_RS22555	COG1116	anion transmembrane transporter activity
DTO10_RS22560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DTO10_RS22565	COG4521	taurine ABC transporter
DTO10_RS22570	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS22570	COG0604	alcohol dehydrogenase
DTO10_RS22570	COG3321	synthase
DTO10_RS22575	COG1525	nuclease
DTO10_RS22575	COG0737	Belongs to the 5'-nucleotidase family
DTO10_RS22575	COG4085	toxin activity
DTO10_RS22585	COG0346	lactoylglutathione lyase activity
DTO10_RS22590	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DTO10_RS22610	COG1819	glycosyl
DTO10_RS22620	COG1309	transcriptional regulator
DTO10_RS22625	COG0456	acetyltransferase
DTO10_RS22625	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DTO10_RS22650	COG0247	lactate metabolic process
DTO10_RS22655	COG0277	FAD linked oxidase domain protein
DTO10_RS22660	COG2186	Transcriptional regulator
DTO10_RS22680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DTO10_RS22685	COG2814	Major facilitator Superfamily
DTO10_RS22700	COG0697	spore germination
DTO10_RS22705	COG2364	Membrane
DTO10_RS22720	COG0596	Alpha beta hydrolase
DTO10_RS22745	COG1024	Enoyl-CoA hydratase
DTO10_RS22750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DTO10_RS22755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DTO10_RS22760	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS22760	COG0604	alcohol dehydrogenase
DTO10_RS22760	COG3321	synthase
DTO10_RS22770	COG1802	Transcriptional regulator
DTO10_RS22775	COG1024	Enoyl-CoA hydratase
DTO10_RS22780	COG1119	ATPase activity
DTO10_RS22810	COG1072	(Pantothenic acid kinase))
DTO10_RS22820	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DTO10_RS22825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DTO10_RS22825	COG2190	(PTS) system
DTO10_RS22825	COG1263	PTS System
DTO10_RS22835	COG2890	protein-(glutamine-N5) methyltransferase activity
DTO10_RS22855	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DTO10_RS22860	COG2271	Major facilitator Superfamily
DTO10_RS22865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DTO10_RS22875	COG1388	LysM domain
DTO10_RS22875	COG3858	chitin binding
DTO10_RS22895	COG0531	amino acid
DTO10_RS22900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DTO10_RS22915	COG1388	LysM domain
DTO10_RS22915	COG3584	3D domain protein
DTO10_RS22940	COG1937	Protein conserved in bacteria
DTO10_RS22950	COG2210	Belongs to the sulfur carrier protein TusA family
DTO10_RS22960	COG0425	Belongs to the sulfur carrier protein TusA family
DTO10_RS22960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DTO10_RS22965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DTO10_RS22965	COG0425	Belongs to the sulfur carrier protein TusA family
DTO10_RS22975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DTO10_RS22975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DTO10_RS22980	COG0425	Belongs to the sulfur carrier protein TusA family
DTO10_RS22985	COG0730	response to heat
DTO10_RS23015	COG1024	Enoyl-CoA hydratase
DTO10_RS23025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DTO10_RS23030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DTO10_RS23040	COG0583	DNA-binding transcription factor activity
DTO10_RS23050	COG0733	neurotransmitter:sodium symporter activity
DTO10_RS23060	COG0583	DNA-binding transcription factor activity
DTO10_RS23065	COG2610	gluconate transmembrane transporter activity
DTO10_RS23075	COG0577	efflux transmembrane transporter activity
DTO10_RS23080	COG1136	(ABC) transporter
DTO10_RS23095	COG5002	protein histidine kinase activity
DTO10_RS23100	COG0745	RESPONSE REGULATOR receiver
DTO10_RS23135	COG1116	anion transmembrane transporter activity
DTO10_RS23140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DTO10_RS23155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_RS23175	COG3361	conserved protein (COG2071)
DTO10_RS23180	COG0069	glutamate synthase activity
DTO10_RS23180	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DTO10_RS23190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DTO10_RS23195	COG3689	TIGRFAM TIGR03943 family protein
DTO10_RS23200	COG0701	Predicted permease
DTO10_RS23205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DTO10_RS23210	COG1937	Protein conserved in bacteria
DTO10_RS23215	COG2608	mercury ion transmembrane transporter activity
DTO10_RS23220	COG2217	Heavy metal translocating P-type atpase
DTO10_RS23230	COG0747	negative chemotaxis
DTO10_RS23235	COG0601	transmembrane transport
DTO10_RS23240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DTO10_RS23245	COG0444	Belongs to the ABC transporter superfamily
DTO10_RS23250	COG4608	Belongs to the ABC transporter superfamily
DTO10_RS23265	COG3540	Alkaline phosphatase
DTO10_RS23270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DTO10_RS23275	COG0805	protein transport
DTO10_RS23280	COG4974	Belongs to the 'phage' integrase family
DTO10_RS23295	COG3378	Phage plasmid primase P4 family
DTO10_RS23300	COG5297	Belongs to the glycosyl hydrolase family 6
DTO10_RS23300	COG4733	cellulase activity
DTO10_RS23345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DTO10_RS23375	COG2329	Antibiotic biosynthesis monooxygenase
DTO10_RS23420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DTO10_RS23460	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DTO10_RS23485	COG0582	viral genome integration into host DNA
DTO10_RS23505	COG2832	Protein of unknown function (DUF454)
DTO10_RS23510	COG2323	membrane
DTO10_RS23520	COG3829	transcription factor binding
DTO10_RS23520	COG3290	protein histidine kinase activity
DTO10_RS23535	COG1113	amino acid transport
DTO10_RS23545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DTO10_RS23555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DTO10_RS23575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DTO10_RS23580	COG2364	Membrane
DTO10_RS23585	COG2153	protein acetylation
DTO10_RS23590	COG1846	Transcriptional regulator
DTO10_RS23595	COG1132	(ABC) transporter
DTO10_RS23605	COG1846	Transcriptional regulator
DTO10_RS23615	COG0531	amino acid
DTO10_RS23625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DTO10_RS23630	COG0022	dehydrogenase e1 component
DTO10_RS23635	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_RS23650	COG0346	lactoylglutathione lyase activity
DTO10_RS23660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_RS23665	COG0697	spore germination
DTO10_RS23685	COG2271	Major facilitator Superfamily
DTO10_RS23690	COG0277	FAD linked oxidase domain protein
DTO10_RS23695	COG1309	transcriptional regulator
DTO10_RS23710	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DTO10_RS23715	COG1228	amidohydrolase
DTO10_RS23725	COG2271	Major facilitator Superfamily
DTO10_RS23735	COG0477	Major facilitator Superfamily
DTO10_RS23740	COG2986	histidine ammonia-lyase
DTO10_RS23750	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DTO10_RS23755	COG1914	H( )-stimulated, divalent metal cation uptake system
DTO10_RS23760	COG4336	lyase activity
DTO10_RS23765	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DTO10_RS23770	COG1984	allophanate hydrolase subunit 2
DTO10_RS23780	COG0243	molybdopterin cofactor binding
DTO10_RS23810	COG2223	nitrite transmembrane transporter activity
DTO10_RS23820	COG2197	response regulator
DTO10_RS23830	COG4585	Histidine kinase
DTO10_RS23835	COG1414	Transcriptional regulator
DTO10_RS23850	COG0583	DNA-binding transcription factor activity
DTO10_RS23855	COG2358	TRAP transporter, solute receptor (TAXI family
DTO10_RS23870	COG0405	Gamma-glutamyltransferase
DTO10_RS23875	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS23880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_RS23885	COG0765	amino acid transport
DTO10_RS23890	COG0765	amino acid transport
DTO10_RS23895	COG1126	abc transporter atp-binding protein
DTO10_RS23900	COG2135	peptidase activity
DTO10_RS23910	COG1115	amino acid carrier protein
DTO10_RS23920	COG0861	Integral membrane protein TerC family
DTO10_RS23935	COG1122	ATPase activity
DTO10_RS23950	COG0310	cobalt ion transport
DTO10_RS24015	COG0778	Nitroreductase
DTO10_RS24025	COG1492	cobalamin metabolic process
DTO10_RS24040	COG0515	serine threonine protein kinase
DTO10_RS24045	COG3878	Protein conserved in bacteria
DTO10_RS24065	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS24075	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DTO10_RS24080	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS24090	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS24095	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DTO10_RS24100	COG4721	ABC-type cobalt transport system, permease component
DTO10_RS24105	COG1122	ATPase activity
DTO10_RS24115	COG0352	thiamine-phosphate diphosphorylase activity
DTO10_RS24120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DTO10_RS24130	COG2022	thiamine diphosphate biosynthetic process
DTO10_RS24135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DTO10_RS24155	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DTO10_RS24160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_RS24180	COG0824	Thioesterase
DTO10_RS24190	COG4841	protein insertion into membrane
DTO10_RS24195	COG2816	NAD+ diphosphatase activity
DTO10_RS24200	COG1695	Transcriptional regulator
DTO10_RS24205	COG3093	addiction module antidote protein HigA
DTO10_RS24210	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DTO10_RS24215	COG1832	CoA-binding protein
DTO10_RS24220	COG0187	DNA topoisomerase II activity
DTO10_RS24225	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DTO10_RS24230	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS24235	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS24240	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS24265	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS24280	COG0559	Belongs to the binding-protein-dependent transport system permease family
DTO10_RS24315	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DTO10_RS24320	COG1737	Transcriptional regulator
DTO10_RS24325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DTO10_RS24325	COG1263	PTS System
DTO10_RS24335	COG1472	Belongs to the glycosyl hydrolase 3 family
DTO10_RS24340	COG3876	Protein conserved in bacteria
DTO10_RS24345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DTO10_RS24345	COG1263	PTS System
DTO10_RS24355	COG0673	inositol 2-dehydrogenase activity
DTO10_RS24365	COG2814	Major facilitator Superfamily
DTO10_RS24375	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS24380	COG3964	amidohydrolase
DTO10_RS24400	COG2188	Transcriptional regulator
DTO10_RS24425	COG1414	Transcriptional regulator
DTO10_RS24440	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS24445	COG0028	Belongs to the TPP enzyme family
DTO10_RS24450	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS24460	COG4638	Rieske (2fe-2S)
DTO10_RS24470	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS24480	COG1141	Ferredoxin
DTO10_RS24495	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS24500	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_RS24505	COG0183	Belongs to the thiolase family
DTO10_RS24510	COG3290	protein histidine kinase activity
DTO10_RS24510	COG3829	transcription factor binding
DTO10_RS24515	COG2610	gluconate transmembrane transporter activity
DTO10_RS24520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DTO10_RS24525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DTO10_RS24550	COG1607	acyl-coa hydrolase
DTO10_RS24555	COG1271	oxidase subunit
DTO10_RS24560	COG1294	oxidase, subunit
DTO10_RS24570	COG1309	transcriptional regulator
DTO10_RS24575	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS24580	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS24585	COG0439	Biotin carboxylase
DTO10_RS24590	COG0511	ligase activity, forming carbon-carbon bonds
DTO10_RS24595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DTO10_RS24600	COG1024	Enoyl-CoA hydratase
DTO10_RS24605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DTO10_RS24610	COG0494	nUDIX hydrolase
DTO10_RS24615	COG1335	isochorismatase
DTO10_RS24620	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DTO10_RS24670	COG1876	peptidase activity
DTO10_RS24705	COG1404	Belongs to the peptidase S8 family
DTO10_RS24710	COG1714	RDD family
DTO10_RS24740	COG1335	isochorismatase
DTO10_RS24755	COG0531	amino acid
DTO10_RS24760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DTO10_RS24770	COG2814	Major facilitator Superfamily
DTO10_RS24780	COG2814	Major facilitator Superfamily
DTO10_RS24785	COG1742	UPF0060 membrane protein
DTO10_RS24790	COG0697	spore germination
DTO10_RS24805	COG2267	carboxylic ester hydrolase activity
DTO10_RS24815	COG2267	carboxylic ester hydrolase activity
DTO10_RS24820	COG0596	Alpha beta hydrolase
DTO10_RS24820	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_RS24835	COG3290	protein histidine kinase activity
DTO10_RS24835	COG3829	transcription factor binding
DTO10_RS24840	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS24845	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS24850	COG2271	Major facilitator Superfamily
DTO10_RS24865	COG3243	poly(R)-hydroxyalkanoic acid synthase
DTO10_RS24870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_RS24930	COG0583	DNA-binding transcription factor activity
DTO10_RS24935	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS24960	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS24970	COG2271	Major facilitator Superfamily
DTO10_RS24980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DTO10_RS24985	COG0583	DNA-binding transcription factor activity
DTO10_RS24990	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS25000	COG0300	oxidoreductase activity
DTO10_RS25005	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS25015	COG0183	Belongs to the thiolase family
DTO10_RS25050	COG0542	response to heat
DTO10_RS25055	COG1523	belongs to the glycosyl hydrolase 13 family
DTO10_RS25075	COG4294	response to UV
DTO10_RS25080	COG0582	viral genome integration into host DNA
DTO10_RS25090	COG1802	Transcriptional regulator
DTO10_RS25095	COG0579	oxidoreductase
DTO10_RS25115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DTO10_RS25130	COG0069	glutamate synthase activity
DTO10_RS25135	COG3835	regulator
DTO10_RS25140	COG1929	Belongs to the glycerate kinase type-1 family
DTO10_RS25145	COG2610	gluconate transmembrane transporter activity
DTO10_RS25180	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DTO10_RS25195	COG3852	Histidine kinase
DTO10_RS25200	COG2204	response regulator
DTO10_RS25210	COG1840	ABC-type Fe3 transport system, periplasmic component
DTO10_RS25215	COG3842	ATPase activity
DTO10_RS25220	COG1176	ABC-type spermidine putrescine transport system, permease component I
DTO10_RS25260	COG0596	Alpha beta hydrolase
DTO10_RS25265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DTO10_RS25290	COG3284	Transcriptional regulator
DTO10_RS25295	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS25300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DTO10_RS25305	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_RS25310	COG0022	dehydrogenase e1 component
DTO10_RS25315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DTO10_RS25320	COG1309	transcriptional regulator
DTO10_RS25330	COG2814	Major facilitator Superfamily
DTO10_RS25335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DTO10_RS25340	COG5002	protein histidine kinase activity
DTO10_RS25345	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS25350	COG1160	GTP binding
DTO10_RS25360	COG0024	Methionine aminopeptidase
DTO10_RS25380	COG1309	transcriptional regulator
DTO10_RS25435	COG2207	Transcriptional regulator
DTO10_RS25435	COG1917	Cupin 2, conserved barrel domain protein
DTO10_RS25440	COG0697	spore germination
DTO10_RS25445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DTO10_RS25450	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS25455	COG1070	Carbohydrate kinase
DTO10_RS25460	COG3775	system Galactitol-specific IIC component
DTO10_RS25470	COG1830	Aldolase
DTO10_RS25480	COG1301	dicarboxylic acid transport
DTO10_RS25485	COG0028	Belongs to the TPP enzyme family
DTO10_RS25490	COG0436	Aminotransferase
DTO10_RS25505	COG1414	Transcriptional regulator
DTO10_RS25510	COG1011	Hydrolase
DTO10_RS25535	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DTO10_RS25540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DTO10_RS25555	COG0668	transmembrane transport
DTO10_RS25575	COG2234	aminopeptidase activity
DTO10_RS25615	COG0583	DNA-binding transcription factor activity
DTO10_RS25640	COG2234	aminopeptidase activity
DTO10_RS25660	COG2271	Major facilitator Superfamily
DTO10_RS25665	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS25675	COG0583	DNA-binding transcription factor activity
DTO10_RS25680	COG4191	Histidine kinase
DTO10_RS25685	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DTO10_RS25690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DTO10_RS25695	COG0583	DNA-binding transcription factor activity
DTO10_RS25700	COG0741	lytic transglycosylase activity
DTO10_RS25745	COG2301	Belongs to the HpcH HpaI aldolase family
DTO10_RS25755	COG2851	Citrate transporter
DTO10_RS25760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DTO10_RS25765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DTO10_RS25770	COG1802	Transcriptional regulator
DTO10_RS25775	COG1473	amidohydrolase
DTO10_RS25780	COG1288	antiporter activity
DTO10_RS25795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_RS25810	COG4608	Belongs to the ABC transporter superfamily
DTO10_RS25815	COG0444	Belongs to the ABC transporter superfamily
DTO10_RS25825	COG0601	transmembrane transport
DTO10_RS25845	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS25850	COG0473	3-isopropylmalate dehydrogenase activity
DTO10_RS25855	COG3290	protein histidine kinase activity
DTO10_RS25855	COG3829	transcription factor binding
DTO10_RS25885	COG2205	protein histidine kinase activity
DTO10_RS25895	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DTO10_RS25900	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DTO10_RS25910	COG5609	conserved protein (DUF2294)
DTO10_RS25920	COG3409	Peptidoglycan-binding domain 1 protein
DTO10_RS25920	COG3773	Cell wall hydrolase
DTO10_RS25930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_RS25960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_RS25975	COG3540	Alkaline phosphatase
DTO10_RS25980	COG3540	Alkaline phosphatase
DTO10_RS25985	COG0584	glycerophosphoryl diester phosphodiesterase
DTO10_RS26015	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DTO10_RS26020	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS26035	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS26065	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DTO10_RS26075	COG3344	reverse transcriptase
DTO10_RS26095	COG0584	glycerophosphoryl diester phosphodiesterase
DTO10_RS26140	COG1164	Oligoendopeptidase f
DTO10_RS26155	COG0788	formyltetrahydrofolate deformylase activity
DTO10_RS26160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DTO10_RS26170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DTO10_RS26175	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DTO10_RS26180	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DTO10_RS26185	COG0509	glycine decarboxylation via glycine cleavage system
DTO10_RS26195	COG1760	l-serine dehydratase
DTO10_RS26200	COG1760	l-serine dehydratase
DTO10_RS26210	COG1113	amino acid transport
DTO10_RS26215	COG2076	Multidrug Resistance protein
DTO10_RS26220	COG2076	Multidrug Resistance protein
DTO10_RS26225	COG0561	phosphatase activity
DTO10_RS26230	COG1349	DNA-binding transcription factor activity
DTO10_RS26270	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS26280	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS26285	COG0531	amino acid
DTO10_RS26290	COG0789	Transcriptional regulator
DTO10_RS26290	COG4978	Transcriptional regulator
DTO10_RS26380	COG3321	synthase
DTO10_RS26380	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_RS26380	COG0604	alcohol dehydrogenase
DTO10_RS26410	COG1695	Transcriptional regulator
DTO10_RS26415	COG2132	Multicopper oxidase
DTO10_RS26450	COG0656	L-ascorbic acid biosynthetic process
DTO10_RS26455	COG0789	Transcriptional regulator
DTO10_RS26495	COG0590	tRNA wobble adenosine to inosine editing
DTO10_RS26525	COG2329	Antibiotic biosynthesis monooxygenase
DTO10_RS26530	COG0024	Methionine aminopeptidase
DTO10_RS26535	COG2808	Putative FMN-binding domain
DTO10_RS26540	COG0456	acetyltransferase
DTO10_RS26545	COG1846	Transcriptional regulator
DTO10_RS26565	COG2843	Capsule synthesis protein
DTO10_RS26620	COG0179	Fumarylacetoacetate (FAA) hydrolase
DTO10_RS26625	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS26630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DTO10_RS26660	COG3858	chitin binding
DTO10_RS26685	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_RS26690	COG1957	nucleoside hydrolase
DTO10_RS26695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DTO10_RS26705	COG1522	sequence-specific DNA binding
DTO10_RS26705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DTO10_RS26715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DTO10_RS26725	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_RS26730	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS26735	COG1960	acyl-CoA dehydrogenase activity
DTO10_RS26755	COG2030	dehydratase
DTO10_RS27020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DTO10_RS27375	COG2610	gluconate transmembrane transporter activity