locus-tag	class	description
PGA1_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PGA1_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PGA1_RS00030	COG0431	NADPH-dependent FMN reductase
PGA1_RS00100	COG1846	Transcriptional regulator
PGA1_RS00130	COG0582	viral genome integration into host DNA
PGA1_RS00145	COG4176	ABC-type proline glycine betaine transport system permease component
PGA1_RS00160	COG0587	DNA-directed DNA polymerase activity
PGA1_RS00175	COG3046	protein related to deoxyribodipyrimidine photolyase
PGA1_RS00180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PGA1_RS00190	COG0625	glutathione transferase activity
PGA1_RS00215	COG0179	Fumarylacetoacetate (FAA) hydrolase
PGA1_RS00220	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PGA1_RS00245	COG0489	protein tyrosine kinase activity
PGA1_RS00245	COG2151	metal-sulfur cluster biosynthetic enzyme
PGA1_RS00250	COG0254	rRNA binding
PGA1_RS00255	COG0335	large ribosomal subunit rRNA binding
PGA1_RS00260	COG0336	Belongs to the RNA methyltransferase TrmD family
PGA1_RS00270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PGA1_RS00275	COG0778	Nitroreductase
PGA1_RS00280	COG0228	four-way junction DNA binding
PGA1_RS00295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PGA1_RS00305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PGA1_RS00310	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PGA1_RS00345	COG0356	it plays a direct role in the translocation of protons across the membrane
PGA1_RS00350	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGA1_RS00355	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PGA1_RS00360	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PGA1_RS00370	COG2186	Transcriptional regulator
PGA1_RS00400	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PGA1_RS00410	COG0435	Glutathione S-transferase
PGA1_RS00420	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PGA1_RS00425	COG0242	peptide deformylase activity
PGA1_RS00430	COG0242	peptide deformylase activity
PGA1_RS00435	COG0242	peptide deformylase activity
PGA1_RS00440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PGA1_RS00450	COG2860	membrane
PGA1_RS00455	COG0328	RNA-DNA hybrid ribonuclease activity
PGA1_RS00475	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PGA1_RS00485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PGA1_RS00490	COG1758	RNA polymerase activity
PGA1_RS00505	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PGA1_RS00510	COG0736	holo-[acyl-carrier-protein] synthase activity
PGA1_RS00515	COG0681	Belongs to the peptidase S26 family
PGA1_RS00520	COG0571	ribonuclease III activity
PGA1_RS00525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PGA1_RS00535	COG1381	Involved in DNA repair and RecF pathway recombination
PGA1_RS00555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PGA1_RS00560	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PGA1_RS00565	COG0745	RESPONSE REGULATOR receiver
PGA1_RS00570	COG2205	protein histidine kinase activity
PGA1_RS00580	COG1660	Displays ATPase and GTPase activities
PGA1_RS00590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PGA1_RS00600	COG1250	3-hydroxyacyl-CoA dehydrogenase
PGA1_RS00620	COG2096	Adenosyltransferase
PGA1_RS00630	COG0300	oxidoreductase activity
PGA1_RS00640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGA1_RS00650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PGA1_RS00675	COG0250	Participates in transcription elongation, termination and antitermination
PGA1_RS00685	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PGA1_RS00690	COG0081	regulation of translation
PGA1_RS00695	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PGA1_RS00700	COG0222	ribosome binding
PGA1_RS00705	COG0085	RNA polymerase activity
PGA1_RS00710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGA1_RS00730	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PGA1_RS00735	COG0049	tRNA binding
PGA1_RS00740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PGA1_RS00745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PGA1_RS00755	COG0051	transcription antitermination factor activity, RNA binding
PGA1_RS00760	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PGA1_RS00765	COG0088	Forms part of the polypeptide exit tunnel
PGA1_RS00770	COG0089	rRNA binding
PGA1_RS00780	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PGA1_RS00785	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PGA1_RS00790	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PGA1_RS00795	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PGA1_RS00800	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PGA1_RS00825	COG0255	Belongs to the universal ribosomal protein uL29 family
PGA1_RS00830	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PGA1_RS00835	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PGA1_RS00840	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PGA1_RS00845	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PGA1_RS00850	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PGA1_RS00855	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PGA1_RS00860	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PGA1_RS00865	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PGA1_RS00870	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PGA1_RS00875	COG1841	ribosomal large subunit assembly
PGA1_RS00890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGA1_RS00910	COG0200	Binds to the 23S rRNA
PGA1_RS00915	COG0201	protein transport
PGA1_RS00920	COG0563	adenylate kinase activity
PGA1_RS00925	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PGA1_RS00930	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PGA1_RS00935	COG0202	RNA polymerase activity
PGA1_RS00940	COG0203	ribosomal protein L17
PGA1_RS00945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PGA1_RS00950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PGA1_RS00955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PGA1_RS00965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PGA1_RS00975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PGA1_RS00980	COG4597	amino acid ABC transporter
PGA1_RS00985	COG0765	amino acid transport
PGA1_RS00990	COG1126	abc transporter atp-binding protein
PGA1_RS01010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PGA1_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS01020	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PGA1_RS01030	COG0706	membrane insertase activity
PGA1_RS01040	COG0037	tRNA processing
PGA1_RS01050	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PGA1_RS01055	COG0594	ribonuclease P activity
PGA1_RS01060	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PGA1_RS01075	COG4191	Histidine kinase
PGA1_RS01135	COG0668	transmembrane transport
PGA1_RS01140	COG2116	formate transmembrane transporter activity
PGA1_RS01160	COG0789	Transcriptional regulator
PGA1_RS01165	COG2814	Major facilitator Superfamily
PGA1_RS01170	COG3591	Belongs to the peptidase S1B family
PGA1_RS01175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PGA1_RS01180	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
PGA1_RS01195	COG2766	serine protein kinase
PGA1_RS01200	COG2718	Belongs to the UPF0229 family
PGA1_RS01205	COG2719	SpoVR family
PGA1_RS01210	COG1802	Transcriptional regulator
PGA1_RS01215	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PGA1_RS01235	COG3485	protocatechuate 3,4-dioxygenase
PGA1_RS01240	COG3485	protocatechuate 3,4-dioxygenase
PGA1_RS01245	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PGA1_RS01250	COG0583	DNA-binding transcription factor activity
PGA1_RS01260	COG4214	carbohydrate transport
PGA1_RS01275	COG1022	Amp-dependent synthetase and ligase
PGA1_RS01295	COG0604	alcohol dehydrogenase
PGA1_RS01310	COG1609	Transcriptional regulator
PGA1_RS01315	COG1653	transport
PGA1_RS01325	COG0395	ABC-type sugar transport system, permease component
PGA1_RS01330	COG3842	ATPase activity
PGA1_RS01340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PGA1_RS01340	COG2169	Transcriptional regulator
PGA1_RS01345	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PGA1_RS01355	COG0793	Belongs to the peptidase S41A family
PGA1_RS01375	COG1131	(ABC) transporter
PGA1_RS01380	COG0842	Transport permease protein
PGA1_RS01400	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS01405	COG0322	excinuclease ABC activity
PGA1_RS01410	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PGA1_RS01420	COG0314	molybdopterin synthase activity
PGA1_RS01430	COG2885	chlorophyll binding
PGA1_RS01440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PGA1_RS01470	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PGA1_RS01495	COG0540	Belongs to the ATCase OTCase family
PGA1_RS01500	COG1573	uracil-dna glycosylase
PGA1_RS01505	COG0521	Mo-molybdopterin cofactor biosynthetic process
PGA1_RS01515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PGA1_RS01520	COG0494	nUDIX hydrolase
PGA1_RS01530	COG1678	Uncharacterized ACR, COG1678
PGA1_RS01535	COG0009	L-threonylcarbamoyladenylate synthase
PGA1_RS01540	COG1960	acyl-CoA dehydrogenase activity
PGA1_RS01580	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PGA1_RS01585	COG0746	molybdenum cofactor guanylyltransferase activity
PGA1_RS01590	COG1763	Mo-molybdopterin cofactor biosynthetic process
PGA1_RS01600	COG0303	'Molybdopterin
PGA1_RS01610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PGA1_RS01620	COG0789	Transcriptional regulator
PGA1_RS01635	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PGA1_RS01640	COG0142	geranyltranstransferase activity
PGA1_RS01665	COG0583	DNA-binding transcription factor activity
PGA1_RS01670	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS01695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PGA1_RS01700	COG0165	Argininosuccinate lyase
PGA1_RS01710	COG0019	diaminopimelate decarboxylase activity
PGA1_RS01725	COG2884	Cell division ATP-binding protein ftsE
PGA1_RS01770	COG0508	dehydrogenase complex catalyzes the overall conversion of
PGA1_RS01790	COG0045	succinate-CoA ligase (ADP-forming) activity
PGA1_RS01800	COG0039	L-malate dehydrogenase activity
PGA1_RS01830	COG2030	dehydratase
PGA1_RS01875	COG0019	diaminopimelate decarboxylase activity
PGA1_RS01885	COG0813	purine-nucleoside phosphorylase activity
PGA1_RS01895	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PGA1_RS01895	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PGA1_RS01910	COG0604	alcohol dehydrogenase
PGA1_RS01930	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS01940	COG0730	response to heat
PGA1_RS01945	COG1079	Belongs to the binding-protein-dependent transport system permease family
PGA1_RS01950	COG4603	Belongs to the binding-protein-dependent transport system permease family
PGA1_RS01955	COG3845	ABC transporter
PGA1_RS01960	COG1744	ABC transporter substrate-binding protein PnrA-like
PGA1_RS01970	COG1214	PFAM Peptidase M22, glycoprotease
PGA1_RS01975	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PGA1_RS01995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PGA1_RS02000	COG2151	metal-sulfur cluster biosynthetic enzyme
PGA1_RS02005	COG3396	Phenylacetate-CoA oxygenase
PGA1_RS02010	COG3460	Phenylacetate-CoA oxygenase
PGA1_RS02015	COG3396	Phenylacetate-CoA oxygenase
PGA1_RS02030	COG1250	3-hydroxyacyl-CoA dehydrogenase
PGA1_RS02030	COG1024	Enoyl-CoA hydratase
PGA1_RS02035	COG0183	Belongs to the thiolase family
PGA1_RS02040	COG1960	acyl-CoA dehydrogenase activity
PGA1_RS02045	COG1960	acyl-CoA dehydrogenase activity
PGA1_RS02055	COG0318	PFAM AMP-dependent synthetase and ligase
PGA1_RS02065	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PGA1_RS02070	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PGA1_RS02075	COG3639	organic phosphonate transmembrane transporter activity
PGA1_RS02080	COG3639	organic phosphonate transmembrane transporter activity
PGA1_RS02085	COG0110	maltose O-acetyltransferase activity
PGA1_RS02090	COG2188	Transcriptional regulator
PGA1_RS02095	COG3624	Phosphonate C-P lyase system protein PhnG
PGA1_RS02105	COG3626	phosphonate metabolism
PGA1_RS02115	COG3627	carbon phosphorus lyase activity
PGA1_RS02120	COG4107	phosphonate C-P lyase system protein PhnK
PGA1_RS02125	COG4778	phosphonate C-P lyase system protein PhnL
PGA1_RS02140	COG3454	Phosphonate metabolism
PGA1_RS02160	COG0588	phosphoglycerate mutase activity
PGA1_RS02165	COG0438	transferase activity, transferring glycosyl groups
PGA1_RS02180	COG0668	transmembrane transport
PGA1_RS02185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PGA1_RS02190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGA1_RS02195	COG0601	transmembrane transport
PGA1_RS02230	COG1522	sequence-specific DNA binding
PGA1_RS02240	COG1132	(ABC) transporter
PGA1_RS02250	COG4948	Mandelate Racemase Muconate Lactonizing
PGA1_RS02265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PGA1_RS02290	COG1047	Peptidyl-prolyl cis-trans
PGA1_RS02295	COG2070	2-Nitropropane dioxygenase
PGA1_RS02300	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PGA1_RS02305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PGA1_RS02310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PGA1_RS02320	COG0583	DNA-binding transcription factor activity
PGA1_RS02335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PGA1_RS02350	COG1702	phosphate starvation-inducible protein PhoH
PGA1_RS02355	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PGA1_RS02360	COG1253	flavin adenine dinucleotide binding
PGA1_RS02365	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PGA1_RS02370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PGA1_RS02380	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PGA1_RS02385	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PGA1_RS02390	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PGA1_RS02395	COG0539	negative regulation of cytoplasmic translation
PGA1_RS02400	COG0776	regulation of translation
PGA1_RS02410	COG0135	phosphoribosylanthranilate isomerase activity
PGA1_RS02415	COG0133	tryptophan synthase activity
PGA1_RS02430	COG0193	aminoacyl-tRNA hydrolase activity
PGA1_RS02435	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PGA1_RS02445	COG0159	tryptophan synthase activity
PGA1_RS02455	COG0012	GTP binding
PGA1_RS02485	COG4638	Rieske (2fe-2S)
PGA1_RS02540	COG1012	belongs to the aldehyde dehydrogenase family
PGA1_RS02545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PGA1_RS02550	COG0840	transmembrane signaling receptor activity
PGA1_RS02570	COG0395	ABC-type sugar transport system, permease component
PGA1_RS02575	COG1175	transmembrane transport
PGA1_RS02580	COG3842	ATPase activity
PGA1_RS02585	COG3842	ATPase activity
PGA1_RS02595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PGA1_RS02595	COG0116	Belongs to the methyltransferase superfamily
PGA1_RS02620	COG2244	polysaccharide biosynthetic process
PGA1_RS02625	COG0438	transferase activity, transferring glycosyl groups
PGA1_RS02670	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PGA1_RS02685	COG0837	glucose binding
PGA1_RS02710	COG2351	hydroxyisourate hydrolase activity
PGA1_RS02720	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
PGA1_RS02740	COG3257	ureidoglycine aminohydrolase activity
PGA1_RS02760	COG0509	glycine decarboxylation via glycine cleavage system
PGA1_RS02775	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PGA1_RS02780	COG0720	synthase
PGA1_RS02785	COG0602	queuosine metabolic process
PGA1_RS02790	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PGA1_RS02800	COG0101	tRNA pseudouridine synthase activity
PGA1_RS02805	COG3106	COG3106 Predicted ATPase
PGA1_RS02815	COG3768	UPF0283 membrane protein
PGA1_RS02835	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PGA1_RS02845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PGA1_RS02850	COG1183	phosphatidylcholine synthase activity
PGA1_RS02860	COG4974	Belongs to the 'phage' integrase family
PGA1_RS02870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PGA1_RS02880	COG2391	methyltransferase activity
PGA1_RS02890	COG2264	protein methyltransferase activity
PGA1_RS02905	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PGA1_RS02910	COG0632	four-way junction helicase activity
PGA1_RS02915	COG2255	four-way junction helicase activity
PGA1_RS02925	COG0824	Thioesterase
PGA1_RS02945	COG0823	Involved in the tonB-independent uptake of proteins
PGA1_RS02950	COG2885	chlorophyll binding
PGA1_RS02960	COG0037	tRNA processing
PGA1_RS02965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PGA1_RS02975	COG2759	Belongs to the formate--tetrahydrofolate ligase family
PGA1_RS02980	COG0287	Prephenate dehydrogenase
PGA1_RS02980	COG1605	Chorismate mutase
PGA1_RS02985	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PGA1_RS03000	COG1201	RNA secondary structure unwinding
PGA1_RS03045	COG2885	chlorophyll binding
PGA1_RS03050	COG4964	Belongs to the GSP D family
PGA1_RS03065	COG0741	lytic transglycosylase activity
PGA1_RS03085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGA1_RS03090	COG0758	DNA mediated transformation
PGA1_RS03095	COG0312	modulator of DNA gyrase
PGA1_RS03105	COG0109	protoheme IX farnesyltransferase activity
PGA1_RS03115	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PGA1_RS03135	COG0612	Peptidase, M16
PGA1_RS03150	COG2271	Major facilitator Superfamily
PGA1_RS03155	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PGA1_RS03160	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PGA1_RS03165	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PGA1_RS03170	COG0659	secondary active sulfate transmembrane transporter activity
PGA1_RS03180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PGA1_RS03210	COG0752	glycyl-tRNA synthetase alpha subunit
PGA1_RS03220	COG0786	glutamate:sodium symporter activity
PGA1_RS03225	COG0751	glycine-tRNA ligase activity
PGA1_RS03230	COG0574	Belongs to the PEP-utilizing enzyme family
PGA1_RS03230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PGA1_RS03240	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PGA1_RS03245	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PGA1_RS03250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PGA1_RS03265	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PGA1_RS03275	COG1522	sequence-specific DNA binding
PGA1_RS03300	COG1802	Transcriptional regulator
PGA1_RS03310	COG0505	Belongs to the CarA family
PGA1_RS03335	COG0537	adenosine 5'-monophosphoramidase activity
PGA1_RS03345	COG0321	lipoyl(octanoyl) transferase activity
PGA1_RS03370	COG0601	transmembrane transport
PGA1_RS03375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGA1_RS03380	COG0444	Belongs to the ABC transporter superfamily
PGA1_RS03385	COG4608	Belongs to the ABC transporter superfamily
PGA1_RS03390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PGA1_RS03455	COG0469	pyruvate kinase activity
PGA1_RS03465	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PGA1_RS03470	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PGA1_RS03475	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PGA1_RS03485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGA1_RS03485	COG0072	phenylalanine-tRNA ligase activity
PGA1_RS03510	COG0668	transmembrane transport
PGA1_RS03515	COG1970	mechanosensitive ion channel activity
PGA1_RS03525	COG1115	amino acid carrier protein
PGA1_RS03540	COG1858	cytochrome C peroxidase
PGA1_RS03550	COG3391	amine dehydrogenase activity
PGA1_RS03575	COG0673	inositol 2-dehydrogenase activity
PGA1_RS03590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PGA1_RS03595	COG3962	Belongs to the TPP enzyme family
PGA1_RS03600	COG0673	inositol 2-dehydrogenase activity
PGA1_RS03610	COG0673	inositol 2-dehydrogenase activity
PGA1_RS03625	COG4214	carbohydrate transport
PGA1_RS03645	COG0800	Aldolase
PGA1_RS03655	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS03660	COG0129	dihydroxy-acid dehydratase activity
PGA1_RS03670	COG0395	ABC-type sugar transport system, permease component
PGA1_RS03675	COG1175	transmembrane transport
PGA1_RS03705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PGA1_RS03735	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PGA1_RS03740	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PGA1_RS03745	COG1329	Transcriptional regulator
PGA1_RS03755	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PGA1_RS03760	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PGA1_RS03795	COG2873	o-acetylhomoserine
PGA1_RS03815	COG3916	Acyl-homoserine-lactone synthase
PGA1_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS03850	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PGA1_RS03855	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PGA1_RS03855	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PGA1_RS03860	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PGA1_RS03880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PGA1_RS03885	COG0006	proline dipeptidase activity
PGA1_RS03895	COG2723	6-phospho-beta-galactosidase activity
PGA1_RS03900	COG1609	Transcriptional regulator
PGA1_RS03905	COG1653	transport
PGA1_RS03910	COG1175	transmembrane transport
PGA1_RS03915	COG0395	ABC-type sugar transport system, permease component
PGA1_RS03920	COG0366	Alpha amylase catalytic
PGA1_RS03925	COG3842	ATPase activity
PGA1_RS03965	COG1234	tRNA 3'-trailer cleavage
PGA1_RS03970	COG0084	hydrolase, TatD family'
PGA1_RS03980	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PGA1_RS03985	COG1686	Belongs to the peptidase S11 family
PGA1_RS04010	COG1648	precorrin-2 dehydrogenase activity
PGA1_RS04010	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PGA1_RS04015	COG1797	cobyrinic acid a,c-diamide synthase activity
PGA1_RS04020	COG2875	Belongs to the precorrin methyltransferase family
PGA1_RS04035	COG2099	Precorrin-6x reductase
PGA1_RS04135	COG0583	DNA-binding transcription factor activity
PGA1_RS04145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGA1_RS04165	COG0667	Aldo Keto reductase
PGA1_RS04175	COG3246	L-lysine catabolic process to acetate
PGA1_RS04185	COG1250	3-hydroxyacyl-CoA dehydrogenase
PGA1_RS04185	COG0824	Thioesterase
PGA1_RS04190	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS04230	COG1595	DNA-templated transcription, initiation
PGA1_RS04245	COG3706	GGDEF domain
PGA1_RS04265	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
PGA1_RS04290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PGA1_RS04315	COG1741	Belongs to the pirin family
PGA1_RS04340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PGA1_RS04345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PGA1_RS04355	COG0446	pyridine nucleotide-disulphide oxidoreductase
PGA1_RS04355	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PGA1_RS04370	COG0358	DNA primase activity
PGA1_RS04375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGA1_RS04385	COG4221	oxidoreductase activity
PGA1_RS04405	COG0432	Pfam Uncharacterised protein family UPF0047
PGA1_RS04410	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PGA1_RS04415	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PGA1_RS04415	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PGA1_RS04445	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PGA1_RS04450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PGA1_RS04480	COG0564	pseudouridine synthase activity
PGA1_RS04490	COG0840	transmembrane signaling receptor activity
PGA1_RS04495	COG0351	phosphomethylpyrimidine kinase
PGA1_RS04500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PGA1_RS04525	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PGA1_RS04530	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PGA1_RS04540	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PGA1_RS04555	COG4106	trans-aconitate 2-methyltransferase activity
PGA1_RS04560	COG1618	nucleotide phosphatase activity, acting on free nucleotides
PGA1_RS04560	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PGA1_RS04565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGA1_RS04575	COG1832	CoA-binding protein
PGA1_RS04580	COG0140	phosphoribosyl-ATP diphosphatase activity
PGA1_RS04585	COG0107	imidazoleglycerol-phosphate synthase activity
PGA1_RS04600	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PGA1_RS04625	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PGA1_RS04630	COG0131	Imidazoleglycerol-phosphate dehydratase
PGA1_RS04640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PGA1_RS04675	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PGA1_RS04680	COG1304	FMN binding
PGA1_RS04690	COG0210	DNA helicase
PGA1_RS04700	COG0489	protein tyrosine kinase activity
PGA1_RS04705	COG2001	Belongs to the MraZ family
PGA1_RS04710	COG0275	rRNA processing
PGA1_RS04725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PGA1_RS04735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PGA1_RS04740	COG2066	Belongs to the glutaminase family
PGA1_RS04745	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PGA1_RS04750	COG1846	Transcriptional regulator
PGA1_RS04760	COG2081	HI0933 family
PGA1_RS04770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PGA1_RS04775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PGA1_RS04790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PGA1_RS04795	COG1181	Belongs to the D-alanine--D-alanine ligase family
PGA1_RS04800	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PGA1_RS04805	COG0849	cell division
PGA1_RS04810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PGA1_RS04820	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PGA1_RS04845	COG0006	proline dipeptidase activity
PGA1_RS04890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGA1_RS04895	COG2183	response to ionizing radiation
PGA1_RS04910	COG0308	aminopeptidase N
PGA1_RS04920	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PGA1_RS04930	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PGA1_RS04935	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PGA1_RS04935	COG2010	Cytochrome c
PGA1_RS04945	COG1309	transcriptional regulator
PGA1_RS04950	COG3483	tryptophan 2,3-dioxygenase activity
PGA1_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS04985	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PGA1_RS05010	COG2391	methyltransferase activity
PGA1_RS05015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGA1_RS05020	COG0601	transmembrane transport
PGA1_RS05030	COG4172	Belongs to the ABC transporter superfamily
PGA1_RS05040	COG1473	amidohydrolase
PGA1_RS05045	COG1473	amidohydrolase
PGA1_RS05050	COG1473	amidohydrolase
PGA1_RS05060	COG1519	Transferase
PGA1_RS05065	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PGA1_RS05085	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PGA1_RS05105	COG1960	acyl-CoA dehydrogenase activity
PGA1_RS05110	COG3047	cAMP biosynthetic process
PGA1_RS05115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PGA1_RS05125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PGA1_RS05130	COG4770	biotin carboxylase activity
PGA1_RS05145	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PGA1_RS05155	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PGA1_RS05160	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PGA1_RS05165	COG0649	NAD binding
PGA1_RS05205	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PGA1_RS05210	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PGA1_RS05225	COG0713	ATP synthesis coupled electron transport
PGA1_RS05250	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PGA1_RS05260	COG0513	Belongs to the DEAD box helicase family
PGA1_RS05275	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PGA1_RS05290	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS05295	COG4335	DNA alkylation repair
PGA1_RS05300	COG3842	ATPase activity
PGA1_RS05315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PGA1_RS05320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PGA1_RS05325	COG0805	protein transport
PGA1_RS05330	COG0698	ribose 5-phosphate isomerase
PGA1_RS05345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PGA1_RS05350	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PGA1_RS05355	COG4221	oxidoreductase activity
PGA1_RS05370	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PGA1_RS05400	COG1127	ABC transporter
PGA1_RS05405	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PGA1_RS05410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PGA1_RS05415	COG0305	Participates in initiation and elongation during chromosome replication
PGA1_RS05420	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PGA1_RS05425	COG0418	dihydroorotase activity
PGA1_RS05455	COG1162	GTPase activity
PGA1_RS05490	COG0542	response to heat
PGA1_RS05500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PGA1_RS05505	COG1278	Cold shock
PGA1_RS05530	COG0316	Belongs to the HesB IscA family
PGA1_RS05535	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PGA1_RS05545	COG0018	arginyl-trna synthetase
PGA1_RS05565	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PGA1_RS05575	COG0717	Belongs to the dCTP deaminase family
PGA1_RS05590	COG0776	regulation of translation
PGA1_RS05595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PGA1_RS05600	COG0416	fatty acid biosynthetic process
PGA1_RS05605	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PGA1_RS05625	COG0488	(ABC) transporter
PGA1_RS05650	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PGA1_RS05655	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PGA1_RS05665	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PGA1_RS05680	COG0513	Belongs to the DEAD box helicase family
PGA1_RS05690	COG0697	spore germination
PGA1_RS05695	COG0148	phosphopyruvate hydratase activity
PGA1_RS05715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PGA1_RS05715	COG0456	acetyltransferase
PGA1_RS05720	COG1957	nucleoside hydrolase
PGA1_RS05725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PGA1_RS05730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PGA1_RS05735	COG0174	glutamine synthetase
PGA1_RS05740	COG0519	Catalyzes the synthesis of GMP from XMP
PGA1_RS05740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PGA1_RS05745	COG0174	glutamine synthetase
PGA1_RS05755	COG4215	(ABC) transporter
PGA1_RS05790	COG0525	valine-tRNA ligase activity
PGA1_RS05830	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PGA1_RS05835	COG0583	DNA-binding transcription factor activity
PGA1_RS05840	COG0483	inositol monophosphate 1-phosphatase activity
PGA1_RS05860	COG1522	sequence-specific DNA binding
PGA1_RS05915	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PGA1_RS05920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PGA1_RS05925	COG0154	amidase activity
PGA1_RS05935	COG0280	phosphate acetyltransferase
PGA1_RS05935	COG0281	malic enzyme
PGA1_RS05945	COG0295	cytidine deaminase activity
PGA1_RS05950	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PGA1_RS05955	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PGA1_RS05960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PGA1_RS05975	COG0318	PFAM AMP-dependent synthetase and ligase
PGA1_RS05990	COG1024	Enoyl-CoA hydratase
PGA1_RS05990	COG1250	3-hydroxyacyl-CoA dehydrogenase
PGA1_RS05995	COG0183	Belongs to the thiolase family
PGA1_RS06000	COG0625	glutathione transferase activity
PGA1_RS06005	COG1960	acyl-CoA dehydrogenase activity
PGA1_RS06015	COG1960	acyl-CoA dehydrogenase activity
PGA1_RS06020	COG0789	Transcriptional regulator
PGA1_RS06040	COG0534	Mate efflux family protein
PGA1_RS06060	COG0737	Belongs to the 5'-nucleotidase family
PGA1_RS06075	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PGA1_RS06080	COG0709	Synthesizes selenophosphate from selenide and ATP
PGA1_RS06085	COG1320	monovalent cation:proton antiporter activity
PGA1_RS06090	COG2212	antiporter activity
PGA1_RS06100	COG0651	ATP synthesis coupled electron transport
PGA1_RS06105	COG1006	Multisubunit Na H antiporter MnhC subunit
PGA1_RS06110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PGA1_RS06110	COG2111	Na H antiporter
PGA1_RS06125	COG2943	transferase activity, transferring hexosyl groups
PGA1_RS06130	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PGA1_RS06145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PGA1_RS06160	COG2391	methyltransferase activity
PGA1_RS06175	COG0785	Cytochrome C biogenesis protein
PGA1_RS06200	COG3258	Cytochrome c
PGA1_RS06205	COG0737	Belongs to the 5'-nucleotidase family
PGA1_RS06235	COG0740	serine-type endopeptidase activity
PGA1_RS06240	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PGA1_RS06270	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PGA1_RS06275	COG0439	Biotin carboxylase
PGA1_RS06290	COG0410	ABC transporter
PGA1_RS06350	COG2391	methyltransferase activity
PGA1_RS06370	COG3750	Belongs to the UPF0335 family
PGA1_RS06390	COG1309	transcriptional regulator
PGA1_RS06405	COG1116	anion transmembrane transporter activity
PGA1_RS06410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PGA1_RS06415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PGA1_RS06420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PGA1_RS06440	COG0563	adenylate kinase activity
PGA1_RS06445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PGA1_RS06475	COG0745	RESPONSE REGULATOR receiver
PGA1_RS06480	COG2205	protein histidine kinase activity
PGA1_RS06505	COG0673	inositol 2-dehydrogenase activity
PGA1_RS06510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGA1_RS06520	COG4989	oxidoreductase activity
PGA1_RS06540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PGA1_RS06575	COG1175	transmembrane transport
PGA1_RS06595	COG0583	DNA-binding transcription factor activity
PGA1_RS06605	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PGA1_RS06610	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PGA1_RS06620	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PGA1_RS06630	COG2166	iron-sulfur cluster assembly
PGA1_RS06650	COG5012	cobalamin binding
PGA1_RS06660	COG1410	methionine synthase
PGA1_RS06660	COG0646	methionine synthase
PGA1_RS06675	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PGA1_RS06680	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGA1_RS06685	COG0047	phosphoribosylformylglycinamidine synthase activity
PGA1_RS06695	COG2204	response regulator
PGA1_RS06700	COG1530	ribonuclease E activity
PGA1_RS06710	COG0425	Belongs to the sulfur carrier protein TusA family
PGA1_RS06715	COG0785	Cytochrome C biogenesis protein
PGA1_RS06725	COG2124	cytochrome p450
PGA1_RS06740	COG0114	fumarate hydratase activity
PGA1_RS06755	COG2059	Chromate
PGA1_RS06775	COG1136	(ABC) transporter
PGA1_RS06775	COG0577	efflux transmembrane transporter activity
PGA1_RS06840	COG0318	PFAM AMP-dependent synthetase and ligase
PGA1_RS06850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PGA1_RS06860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PGA1_RS06865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PGA1_RS06875	COG1960	acyl-CoA dehydrogenase activity
PGA1_RS06880	COG2091	lysine biosynthetic process via aminoadipic acid
PGA1_RS06890	COG1917	Cupin 2, conserved barrel domain protein
PGA1_RS06890	COG2207	Transcriptional regulator
PGA1_RS06900	COG2186	Transcriptional regulator
PGA1_RS06905	COG0604	alcohol dehydrogenase
PGA1_RS06910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PGA1_RS06920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PGA1_RS06925	COG0415	Belongs to the DNA photolyase family
PGA1_RS06930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PGA1_RS06940	COG0494	nUDIX hydrolase
PGA1_RS06950	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PGA1_RS06950	COG3264	Mechanosensitive ion channel
PGA1_RS06955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PGA1_RS06970	COG2115	Belongs to the xylose isomerase family
PGA1_RS06975	COG1070	Carbohydrate kinase
PGA1_RS06995	COG4536	flavin adenine dinucleotide binding
PGA1_RS07000	COG4974	Belongs to the 'phage' integrase family
PGA1_RS07010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PGA1_RS07015	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PGA1_RS07020	COG0840	transmembrane signaling receptor activity
PGA1_RS07025	COG0629	single-stranded DNA binding
PGA1_RS07030	COG0741	lytic transglycosylase activity
PGA1_RS07030	COG0739	heme binding
PGA1_RS07030	COG1196	nuclear chromosome segregation
PGA1_RS07040	COG4172	Belongs to the ABC transporter superfamily
PGA1_RS07050	COG0601	transmembrane transport
PGA1_RS07065	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PGA1_RS07070	COG0528	UMP kinase activity
PGA1_RS07075	COG0233	cytoplasmic translational termination
PGA1_RS07080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PGA1_RS07090	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PGA1_RS07095	COG0750	zinc metalloprotease
PGA1_RS07100	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PGA1_RS07110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PGA1_RS07115	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PGA1_RS07120	COG3494	Protein of unknown function (DUF1009)
PGA1_RS07125	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PGA1_RS07130	COG0482	sulfurtransferase activity
PGA1_RS07145	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PGA1_RS07150	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PGA1_RS07160	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PGA1_RS07165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PGA1_RS07175	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PGA1_RS07180	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PGA1_RS07195	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PGA1_RS07200	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PGA1_RS07210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGA1_RS07215	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PGA1_RS07225	COG1309	transcriptional regulator
PGA1_RS07230	COG2326	polyphosphate kinase activity
PGA1_RS07240	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
PGA1_RS07255	COG2962	Rard protein
PGA1_RS07265	COG0519	Catalyzes the synthesis of GMP from XMP
PGA1_RS07265	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PGA1_RS07270	COG5598	trimethylamine methyltransferase
PGA1_RS07290	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PGA1_RS07295	COG1473	amidohydrolase
PGA1_RS07305	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PGA1_RS07310	COG2867	negative regulation of translational initiation
PGA1_RS07315	COG0004	ammonium transporteR
PGA1_RS07320	COG1058	Belongs to the CinA family
PGA1_RS07320	COG1546	Belongs to the CinA family
PGA1_RS07325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PGA1_RS07330	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PGA1_RS07330	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PGA1_RS07335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PGA1_RS07340	COG3852	Histidine kinase
PGA1_RS07345	COG2204	response regulator
PGA1_RS07350	COG5000	phosphorelay sensor kinase activity
PGA1_RS07355	COG2204	response regulator
PGA1_RS07365	COG0569	domain protein
PGA1_RS07370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PGA1_RS07375	COG1923	regulation of RNA biosynthetic process
PGA1_RS07380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PGA1_RS07385	COG2366	antibiotic biosynthetic process
PGA1_RS07390	COG2084	Dehydrogenase
PGA1_RS07410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PGA1_RS07415	COG2814	Major facilitator Superfamily
PGA1_RS07455	COG4166	transmembrane transport
PGA1_RS07460	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS07475	COG2313	pseudouridylate synthase activity
PGA1_RS07505	COG1612	heme a metabolic process
PGA1_RS07520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGA1_RS07525	COG5425	PFAM Usg family protein
PGA1_RS07530	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PGA1_RS07555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PGA1_RS07560	COG0516	GMP reductase activity
PGA1_RS07560	COG0517	IMP dehydrogenase activity
PGA1_RS07580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PGA1_RS07585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PGA1_RS07600	COG1217	gtp-binding protein TYPA
PGA1_RS07620	COG2945	thiolester hydrolase activity
PGA1_RS07625	COG1959	2 iron, 2 sulfur cluster binding
PGA1_RS07635	COG0719	Fe-S assembly protein
PGA1_RS07645	COG0393	Putative heavy-metal-binding
PGA1_RS07650	COG0396	ATPase activity
PGA1_RS07655	COG0719	Fe-S assembly protein
PGA1_RS07670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PGA1_RS07690	COG3743	rRNA binding
PGA1_RS07690	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PGA1_RS07695	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PGA1_RS07705	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PGA1_RS07710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PGA1_RS07715	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PGA1_RS07740	COG0052	Belongs to the universal ribosomal protein uS2 family
PGA1_RS07745	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PGA1_RS07750	COG2771	luxR family
PGA1_RS07755	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PGA1_RS07780	COG1024	Enoyl-CoA hydratase
PGA1_RS07785	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PGA1_RS07790	COG1946	Acyl-CoA thioesterase
PGA1_RS07795	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS07800	COG1960	acyl-CoA dehydrogenase activity
PGA1_RS07805	COG0583	DNA-binding transcription factor activity
PGA1_RS07810	COG0745	RESPONSE REGULATOR receiver
PGA1_RS07815	COG0704	Plays a role in the regulation of phosphate uptake
PGA1_RS07820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PGA1_RS07830	COG0573	inorganic phosphate transmembrane transporter activity
PGA1_RS07840	COG5002	protein histidine kinase activity
PGA1_RS07845	COG0626	cystathionine gamma-synthase activity
PGA1_RS07855	COG0194	GDP metabolic process
PGA1_RS07860	COG1561	YicC-like family, N-terminal region
PGA1_RS07870	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PGA1_RS07880	COG2133	pyrroloquinoline quinone binding
PGA1_RS07915	COG0433	COG0433 Predicted ATPase
PGA1_RS07935	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PGA1_RS07940	COG2989	Protein conserved in bacteria
PGA1_RS07945	COG3108	Peptidase M15
PGA1_RS07960	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PGA1_RS07970	COG0248	Ppx GppA phosphatase
PGA1_RS07975	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PGA1_RS08010	COG0577	efflux transmembrane transporter activity
PGA1_RS08040	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PGA1_RS08060	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PGA1_RS08065	COG0235	Class ii aldolase
PGA1_RS08075	COG0747	negative chemotaxis
PGA1_RS08080	COG0601	transmembrane transport
PGA1_RS08085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGA1_RS08090	COG0444	Belongs to the ABC transporter superfamily
PGA1_RS08095	COG4608	Belongs to the ABC transporter superfamily
PGA1_RS08100	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PGA1_RS08110	COG1238	metal cluster binding
PGA1_RS08125	COG0010	Belongs to the arginase family
PGA1_RS08160	COG2814	Major facilitator Superfamily
PGA1_RS08170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PGA1_RS08175	COG0215	cysteine-tRNA ligase activity
PGA1_RS08245	COG1522	sequence-specific DNA binding
PGA1_RS08275	COG3842	ATPase activity
PGA1_RS08280	COG0395	ABC-type sugar transport system, permease component
PGA1_RS08305	COG0004	ammonium transporteR
PGA1_RS08310	COG0738	Major facilitator superfamily
PGA1_RS08315	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGA1_RS08330	COG1278	Cold shock
PGA1_RS08335	COG0259	pyridoxamine-phosphate oxidase activity
PGA1_RS08340	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PGA1_RS08350	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
PGA1_RS08360	COG0436	Aminotransferase
PGA1_RS08365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PGA1_RS08370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PGA1_RS08385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PGA1_RS08390	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PGA1_RS08400	COG0315	cyclic pyranopterin monophosphate synthase activity
PGA1_RS08405	COG0303	'Molybdopterin
PGA1_RS08410	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PGA1_RS08420	COG2333	competence protein COMEC
PGA1_RS08420	COG0658	competence protein
PGA1_RS08425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PGA1_RS08430	COG0372	Belongs to the citrate synthase family
PGA1_RS08440	COG1024	Enoyl-CoA hydratase
PGA1_RS08445	COG3088	subunit of a heme lyase
PGA1_RS08450	COG1138	Cytochrome C-type biogenesis protein
PGA1_RS08465	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PGA1_RS08470	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PGA1_RS08475	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PGA1_RS08490	COG0583	DNA-binding transcription factor activity
PGA1_RS08505	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGA1_RS08515	COG1357	PFAM Pentapeptide repeats (8 copies)
PGA1_RS08530	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PGA1_RS08555	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PGA1_RS08560	COG2354	Protein conserved in bacteria
PGA1_RS08575	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PGA1_RS08580	COG0516	GMP reductase activity
PGA1_RS08580	COG0517	IMP dehydrogenase activity
PGA1_RS08595	COG3239	Fatty acid desaturase
PGA1_RS08625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PGA1_RS08635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PGA1_RS08650	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PGA1_RS08660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PGA1_RS08665	COG2833	Protein of unknown function (DUF455)
PGA1_RS08670	COG0739	heme binding
PGA1_RS08705	COG0126	phosphoglycerate kinase activity
PGA1_RS08710	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PGA1_RS08715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PGA1_RS08720	COG0508	dehydrogenase complex catalyzes the overall conversion of
PGA1_RS08720	COG0022	dehydrogenase e1 component
PGA1_RS08725	COG0508	dehydrogenase complex catalyzes the overall conversion of
PGA1_RS08775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PGA1_RS08865	COG4695	Portal protein
PGA1_RS08880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PGA1_RS08885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PGA1_RS08895	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PGA1_RS08900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGA1_RS08910	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PGA1_RS08930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGA1_RS08935	COG0473	3-isopropylmalate dehydrogenase activity
PGA1_RS08965	COG2353	YceI-like domain
PGA1_RS08980	COG0360	Binds together with S18 to 16S ribosomal RNA
PGA1_RS08985	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PGA1_RS08990	COG0359	binds to the 23S rRNA
PGA1_RS09005	COG0737	Belongs to the 5'-nucleotidase family
PGA1_RS09015	COG0544	peptidyl-prolyl cis-trans isomerase activity
PGA1_RS09025	COG0840	transmembrane signaling receptor activity
PGA1_RS09200	COG3750	Belongs to the UPF0335 family
PGA1_RS09290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PGA1_RS09315	COG0006	proline dipeptidase activity
PGA1_RS09330	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PGA1_RS09365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PGA1_RS09375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PGA1_RS09380	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PGA1_RS09385	COG4133	protoheme IX ABC transporter activity
PGA1_RS09390	COG3737	Protein of unknown function (DUF498/DUF598)
PGA1_RS09395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PGA1_RS09400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PGA1_RS09405	COG1862	Preprotein translocase
PGA1_RS09415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PGA1_RS09425	COG3239	Fatty acid desaturase
PGA1_RS09430	COG1160	GTP binding
PGA1_RS09450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PGA1_RS09460	COG5265	(ABC) transporter
PGA1_RS09505	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PGA1_RS09505	COG0446	pyridine nucleotide-disulphide oxidoreductase
PGA1_RS09515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PGA1_RS09520	COG4235	cytochrome complex assembly
PGA1_RS09525	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PGA1_RS09540	COG0730	response to heat
PGA1_RS09545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PGA1_RS09580	COG1475	DNA binding
PGA1_RS09600	COG1012	belongs to the aldehyde dehydrogenase family
PGA1_RS09605	COG0028	Belongs to the TPP enzyme family
PGA1_RS09615	COG4974	Belongs to the 'phage' integrase family
PGA1_RS09625	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PGA1_RS09640	COG2186	Transcriptional regulator
PGA1_RS09655	COG1175	transmembrane transport
PGA1_RS09660	COG1653	transport
PGA1_RS09690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PGA1_RS09715	COG2197	response regulator
PGA1_RS09720	COG1294	oxidase, subunit
PGA1_RS09725	COG1271	oxidase subunit
PGA1_RS09765	COG0105	UTP biosynthetic process
PGA1_RS09770	COG0488	(ABC) transporter
PGA1_RS09775	COG2095	MarC family integral membrane protein
PGA1_RS09790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PGA1_RS09810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PGA1_RS09815	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PGA1_RS09820	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PGA1_RS09830	COG2890	protein-(glutamine-N5) methyltransferase activity
PGA1_RS09835	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PGA1_RS09855	COG0010	Belongs to the arginase family
PGA1_RS09860	COG1473	amidohydrolase
PGA1_RS09865	COG3956	TIGRFAM MazG family protein
PGA1_RS09875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGA1_RS09885	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PGA1_RS09895	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PGA1_RS09955	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PGA1_RS09960	COG0346	lactoylglutathione lyase activity
PGA1_RS09965	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PGA1_RS09990	COG0028	Belongs to the TPP enzyme family
PGA1_RS09995	COG0440	acetolactate synthase activity
PGA1_RS10020	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PGA1_RS10025	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PGA1_RS10030	COG0860	N-Acetylmuramoyl-L-alanine amidase
PGA1_RS10035	COG0436	Aminotransferase
PGA1_RS10050	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PGA1_RS10060	COG0156	8-amino-7-oxononanoate synthase activity
PGA1_RS10095	COG0406	alpha-ribazole phosphatase activity
PGA1_RS10130	COG1522	sequence-specific DNA binding
PGA1_RS10160	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PGA1_RS10180	COG0343	queuine tRNA-ribosyltransferase activity
PGA1_RS10200	COG0523	cobalamin synthesis protein
PGA1_RS10205	COG2151	metal-sulfur cluster biosynthetic enzyme
PGA1_RS10215	COG0316	Belongs to the HesB IscA family
PGA1_RS10220	COG0149	triose-phosphate isomerase activity
PGA1_RS10225	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PGA1_RS10230	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PGA1_RS10235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PGA1_RS10240	COG2204	response regulator
PGA1_RS10250	COG2124	cytochrome p450
PGA1_RS10260	COG1522	sequence-specific DNA binding
PGA1_RS10265	COG1648	precorrin-2 dehydrogenase activity
PGA1_RS10265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PGA1_RS10275	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PGA1_RS10280	COG0175	sulfate reduction
PGA1_RS10305	COG3443	Belongs to the bacterial solute-binding protein 9 family
PGA1_RS10315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PGA1_RS10320	COG0840	transmembrane signaling receptor activity
PGA1_RS10345	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PGA1_RS10360	COG3243	poly(R)-hydroxyalkanoic acid synthase
PGA1_RS10395	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PGA1_RS10405	COG3220	belongs to the UPF0276 family
PGA1_RS10425	COG1393	Belongs to the ArsC family
PGA1_RS10430	COG1278	Cold shock
PGA1_RS10435	COG1012	belongs to the aldehyde dehydrogenase family
PGA1_RS10440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGA1_RS10450	COG2267	carboxylic ester hydrolase activity
PGA1_RS10460	COG1802	Transcriptional regulator
PGA1_RS10490	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PGA1_RS10505	COG0346	lactoylglutathione lyase activity
PGA1_RS10510	COG1846	Transcriptional regulator
PGA1_RS10555	COG0534	Mate efflux family protein
PGA1_RS10575	COG0187	DNA topoisomerase II activity
PGA1_RS10590	COG0243	molybdopterin cofactor binding
PGA1_RS10600	COG1136	(ABC) transporter
PGA1_RS10610	COG0442	prolyl-tRNA aminoacylation
PGA1_RS10615	COG0628	permease
PGA1_RS10625	COG0248	Ppx GppA phosphatase
PGA1_RS10640	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PGA1_RS10655	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PGA1_RS10655	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PGA1_RS10675	COG4770	biotin carboxylase activity
PGA1_RS10695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PGA1_RS10700	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
PGA1_RS10710	COG3800	Transcriptional regulator
PGA1_RS10710	COG1396	sequence-specific DNA binding
PGA1_RS10735	COG3119	arylsulfatase activity
PGA1_RS10745	COG1309	transcriptional regulator
PGA1_RS10755	COG0697	spore germination
PGA1_RS10780	COG0217	transcriptional regulatory protein
PGA1_RS10785	COG3273	potassium ion transport
PGA1_RS10785	COG0471	metal ion transport
PGA1_RS10795	COG0471	metal ion transport
PGA1_RS10795	COG3273	potassium ion transport
PGA1_RS10800	COG1692	metallophosphoesterase
PGA1_RS10805	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PGA1_RS10810	COG2239	Acts as a magnesium transporter
PGA1_RS10815	COG0402	S-adenosylhomocysteine deaminase activity
PGA1_RS10825	COG0483	inositol monophosphate 1-phosphatase activity
PGA1_RS10830	COG1396	sequence-specific DNA binding
PGA1_RS10835	COG3321	synthase
PGA1_RS10835	COG0604	alcohol dehydrogenase
PGA1_RS10835	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS10840	COG0583	DNA-binding transcription factor activity
PGA1_RS10855	COG0670	Belongs to the BI1 family
PGA1_RS10865	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PGA1_RS10880	COG0154	amidase activity
PGA1_RS10885	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGA1_RS10890	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PGA1_RS10895	COG2818	Glycosylase
PGA1_RS10900	COG0590	tRNA wobble adenosine to inosine editing
PGA1_RS10905	COG1187	pseudouridine synthase activity
PGA1_RS10915	COG3853	Toxic anion resistance protein (TelA)
PGA1_RS10945	COG1490	D-aminoacyl-tRNA deacylase activity
PGA1_RS10955	COG0601	transmembrane transport
PGA1_RS10960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGA1_RS10985	COG0318	PFAM AMP-dependent synthetase and ligase
PGA1_RS10990	COG1132	(ABC) transporter
PGA1_RS11015	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PGA1_RS11135	COG4626	Terminase
PGA1_RS11135	COG1802	Transcriptional regulator
PGA1_RS11250	COG0784	Response regulator, receiver
PGA1_RS11250	COG2198	Histidine kinase
PGA1_RS11250	COG5002	protein histidine kinase activity
PGA1_RS11295	COG1960	acyl-CoA dehydrogenase activity
PGA1_RS11305	COG0183	Belongs to the thiolase family
PGA1_RS11310	COG1024	Enoyl-CoA hydratase
PGA1_RS11310	COG1250	3-hydroxyacyl-CoA dehydrogenase
PGA1_RS11320	COG0318	PFAM AMP-dependent synthetase and ligase
PGA1_RS11325	COG0583	DNA-binding transcription factor activity
PGA1_RS11330	COG4175	Glycine betaine
PGA1_RS11330	COG0517	IMP dehydrogenase activity
PGA1_RS11335	COG4176	ABC-type proline glycine betaine transport system permease component
PGA1_RS11350	COG0741	lytic transglycosylase activity
PGA1_RS11365	COG3451	type IV secretory pathway VirB4
PGA1_RS11370	COG0741	lytic transglycosylase activity
PGA1_RS11370	COG0739	heme binding
PGA1_RS11370	COG1196	nuclear chromosome segregation
PGA1_RS11450	COG4227	nucleotidyltransferase activity
PGA1_RS11460	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PGA1_RS11465	COG1129	ABC transporter
PGA1_RS11475	COG1172	Belongs to the binding-protein-dependent transport system permease family
PGA1_RS11480	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS11485	COG1879	ABC-type sugar transport system periplasmic component
PGA1_RS11500	COG0006	proline dipeptidase activity
PGA1_RS11505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PGA1_RS11510	COG0022	dehydrogenase e1 component
PGA1_RS11515	COG0508	dehydrogenase complex catalyzes the overall conversion of
PGA1_RS11530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PGA1_RS11545	COG3550	peptidyl-serine autophosphorylation
PGA1_RS11565	COG1349	DNA-binding transcription factor activity
PGA1_RS11570	COG2113	Glycine betaine
PGA1_RS11575	COG4175	Glycine betaine
PGA1_RS11575	COG3448	diguanylate cyclase activity
PGA1_RS11610	COG0174	glutamine synthetase
PGA1_RS11635	COG1349	DNA-binding transcription factor activity
PGA1_RS11665	COG1024	Enoyl-CoA hydratase
PGA1_RS11675	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS11685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PGA1_RS11690	COG0527	aspartate kinase activity
PGA1_RS11695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PGA1_RS11705	COG1469	GTP cyclohydrolase I activity
PGA1_RS11715	COG2917	probably involved in intracellular septation
PGA1_RS11725	COG0552	protein localization to endoplasmic reticulum
PGA1_RS11740	COG1570	exodeoxyribonuclease VII activity
PGA1_RS11750	COG3781	membrane
PGA1_RS11795	COG0330	HflC and HflK could
PGA1_RS11800	COG0330	HflC and HflK could
PGA1_RS11815	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PGA1_RS11825	COG0625	glutathione transferase activity
PGA1_RS11830	COG1760	l-serine dehydratase
PGA1_RS11855	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PGA1_RS11890	COG0504	CTP synthase activity
PGA1_RS11895	COG3588	fructose-bisphosphate aldolase
PGA1_RS11900	COG1024	Enoyl-CoA hydratase
PGA1_RS11905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PGA1_RS11910	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PGA1_RS11915	COG1132	(ABC) transporter
PGA1_RS11920	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PGA1_RS11930	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PGA1_RS11940	COG1492	cobalamin metabolic process
PGA1_RS11955	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PGA1_RS11960	COG2824	Alkylphosphonate utilization operon protein PhnA
PGA1_RS11965	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PGA1_RS11970	COG5510	response to toxic substance
PGA1_RS11985	COG0481	GTPase activity
PGA1_RS12005	COG0583	DNA-binding transcription factor activity
PGA1_RS12010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PGA1_RS12025	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PGA1_RS12030	COG1703	isobutyryl-CoA mutase activity
PGA1_RS12035	COG1643	Atp-dependent helicase
PGA1_RS12045	COG0306	phosphate transporter
PGA1_RS12050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PGA1_RS12055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PGA1_RS12065	COG0842	Transport permease protein
PGA1_RS12080	COG0625	glutathione transferase activity
PGA1_RS12105	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PGA1_RS12125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PGA1_RS12150	COG1739	Uncharacterized protein family UPF0029
PGA1_RS12165	COG1872	DUF167
PGA1_RS12170	COG0778	Nitroreductase
PGA1_RS12185	COG0346	lactoylglutathione lyase activity
PGA1_RS12210	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PGA1_RS12220	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PGA1_RS12220	COG0512	Glutamine amidotransferase of anthranilate synthase
PGA1_RS12225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PGA1_RS12235	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PGA1_RS12240	COG3591	Belongs to the peptidase S1B family
PGA1_RS12255	COG1846	Transcriptional regulator
PGA1_RS12265	COG0431	NADPH-dependent FMN reductase
PGA1_RS12275	COG1435	thymidine kinase activity
PGA1_RS12285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGA1_RS12305	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PGA1_RS12315	COG1496	oxidoreductase activity
PGA1_RS12325	COG1522	sequence-specific DNA binding
PGA1_RS12330	COG0492	ferredoxin-NADP+ reductase activity
PGA1_RS12340	COG0529	Catalyzes the synthesis of activated sulfate
PGA1_RS12340	COG2046	Belongs to the sulfate adenylyltransferase family
PGA1_RS12350	COG0384	phenazine biosynthesis protein PhzF
PGA1_RS12360	COG0071	Belongs to the small heat shock protein (HSP20) family
PGA1_RS12370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PGA1_RS12375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PGA1_RS12380	COG3454	Phosphonate metabolism
PGA1_RS12395	COG3153	acetyltransferase
PGA1_RS12400	COG0459	protein refolding
PGA1_RS12405	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PGA1_RS12415	COG1227	inorganic diphosphatase activity
PGA1_RS12430	COG2030	dehydratase
PGA1_RS12435	COG0196	riboflavin kinase activity
PGA1_RS12440	COG2983	Belongs to the UPF0260 family
PGA1_RS12460	COG0596	Alpha beta hydrolase
PGA1_RS12480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PGA1_RS12485	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PGA1_RS12490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PGA1_RS12495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PGA1_RS12500	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGA1_RS12510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PGA1_RS12540	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
PGA1_RS12555	COG0287	Prephenate dehydrogenase
PGA1_RS12560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PGA1_RS12565	COG1522	sequence-specific DNA binding
PGA1_RS12575	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PGA1_RS12585	COG0318	PFAM AMP-dependent synthetase and ligase
PGA1_RS12590	COG0543	2 iron, 2 sulfur cluster binding
PGA1_RS12590	COG0633	Ferredoxin
PGA1_RS12600	COG1902	pentaerythritol trinitrate reductase activity
PGA1_RS12600	COG0446	pyridine nucleotide-disulphide oxidoreductase
PGA1_RS12645	COG0154	amidase activity
PGA1_RS12655	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PGA1_RS12670	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PGA1_RS12690	COG0583	DNA-binding transcription factor activity
PGA1_RS12700	COG4176	ABC-type proline glycine betaine transport system permease component
PGA1_RS12705	COG0517	IMP dehydrogenase activity
PGA1_RS12705	COG4175	Glycine betaine
PGA1_RS12765	COG0446	pyridine nucleotide-disulphide oxidoreductase
PGA1_RS12765	COG1902	pentaerythritol trinitrate reductase activity
PGA1_RS12780	COG3383	formate dehydrogenase (NAD+) activity
PGA1_RS12785	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
PGA1_RS12790	COG0583	DNA-binding transcription factor activity
PGA1_RS12800	COG0840	transmembrane signaling receptor activity
PGA1_RS12810	COG0488	(ABC) transporter
PGA1_RS12835	COG4695	Portal protein
PGA1_RS12860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGA1_RS12865	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGA1_RS12870	COG1120	ATPase activity
PGA1_RS12880	COG0811	peptide transport
PGA1_RS12900	COG4774	siderophore transport
PGA1_RS12915	COG1846	Transcriptional regulator
PGA1_RS12985	COG0556	nucleotide-excision repair
PGA1_RS13030	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
PGA1_RS13055	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PGA1_RS13090	COG1376	ErfK ybiS ycfS ynhG family protein
PGA1_RS13095	COG1278	Cold shock
PGA1_RS13105	COG4181	ATPase activity
PGA1_RS13115	COG1959	2 iron, 2 sulfur cluster binding
PGA1_RS13130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PGA1_RS13135	COG3706	GGDEF domain
PGA1_RS13150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PGA1_RS13155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PGA1_RS13160	COG2957	Belongs to the agmatine deiminase family
PGA1_RS13180	COG0768	penicillin binding
PGA1_RS13185	COG0772	Belongs to the SEDS family
PGA1_RS13190	COG0583	DNA-binding transcription factor activity
PGA1_RS13200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PGA1_RS13210	COG0339	signal peptide processing
PGA1_RS13215	COG0765	amino acid transport
PGA1_RS13220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PGA1_RS13225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PGA1_RS13230	COG0756	dUTP diphosphatase activity
PGA1_RS13235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PGA1_RS13265	COG0606	chelatase, subunit chli
PGA1_RS13275	COG0792	nuclease activity
PGA1_RS13280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PGA1_RS13290	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PGA1_RS13305	COG0180	Tryptophanyl-tRNA synthetase
PGA1_RS13310	COG1278	Cold shock
PGA1_RS13315	COG1309	transcriptional regulator
PGA1_RS13325	COG2050	protein possibly involved in aromatic compounds catabolism
PGA1_RS13330	COG1024	Enoyl-CoA hydratase
PGA1_RS13335	COG1012	belongs to the aldehyde dehydrogenase family
PGA1_RS13335	COG2030	dehydratase
PGA1_RS13340	COG3327	negative regulation of DNA-templated transcription, initiation
PGA1_RS13350	COG1120	ATPase activity
PGA1_RS13360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGA1_RS13365	COG0251	oxidation-reduction process
PGA1_RS13375	COG3845	ABC transporter
PGA1_RS13380	COG4603	Belongs to the binding-protein-dependent transport system permease family
PGA1_RS13385	COG1079	Belongs to the binding-protein-dependent transport system permease family
PGA1_RS13390	COG0402	S-adenosylhomocysteine deaminase activity
PGA1_RS13425	COG3237	CsbD-like
PGA1_RS13450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGA1_RS13470	COG0784	Response regulator, receiver
PGA1_RS13480	COG5487	UPF0391 membrane protein
PGA1_RS13515	COG0174	glutamine synthetase
PGA1_RS13535	COG2175	clavaminate synthase activity
PGA1_RS13540	COG0583	DNA-binding transcription factor activity
PGA1_RS13550	COG0745	RESPONSE REGULATOR receiver
PGA1_RS13555	COG5002	protein histidine kinase activity
PGA1_RS13565	COG4251	negative regulation of phosphorylation
PGA1_RS13570	COG2197	response regulator
PGA1_RS13595	COG1175	transmembrane transport
PGA1_RS13600	COG0395	ABC-type sugar transport system, permease component
PGA1_RS13610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PGA1_RS13620	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS13625	COG1609	Transcriptional regulator
PGA1_RS13640	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PGA1_RS13655	COG0840	transmembrane signaling receptor activity
PGA1_RS13675	COG3806	Anti-sigma factor
PGA1_RS13680	COG1595	DNA-templated transcription, initiation
PGA1_RS13695	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PGA1_RS13720	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS13725	COG3852	Histidine kinase
PGA1_RS13745	COG0437	4 iron, 4 sulfur cluster binding
PGA1_RS13750	COG3383	formate dehydrogenase (NAD+) activity
PGA1_RS13750	COG0243	molybdopterin cofactor binding
PGA1_RS13785	COG0489	protein tyrosine kinase activity
PGA1_RS13805	COG1126	abc transporter atp-binding protein
PGA1_RS13815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PGA1_RS13820	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PGA1_RS13845	COG0463	Glycosyl transferase, family 2
PGA1_RS13855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PGA1_RS13860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PGA1_RS13865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PGA1_RS13870	COG2188	Transcriptional regulator
PGA1_RS13880	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PGA1_RS13890	COG1175	transmembrane transport
PGA1_RS13895	COG0395	ABC-type sugar transport system, permease component
PGA1_RS13900	COG0673	inositol 2-dehydrogenase activity
PGA1_RS13910	COG0166	Belongs to the GPI family
PGA1_RS13915	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PGA1_RS13920	COG0129	dihydroxy-acid dehydratase activity
PGA1_RS13925	COG0800	Aldolase
PGA1_RS13940	COG1072	(Pantothenic acid kinase))
PGA1_RS13980	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PGA1_RS13990	COG3845	ABC transporter
PGA1_RS13995	COG4603	Belongs to the binding-protein-dependent transport system permease family
PGA1_RS14005	COG1079	Belongs to the binding-protein-dependent transport system permease family
PGA1_RS14015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PGA1_RS14045	COG0277	FAD linked oxidase domain protein
PGA1_RS14050	COG0405	Gamma-glutamyltransferase
PGA1_RS14090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PGA1_RS14100	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PGA1_RS14110	COG1280	lysine exporter protein (LysE YggA)
PGA1_RS14130	COG0444	Belongs to the ABC transporter superfamily
PGA1_RS14135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGA1_RS14140	COG0601	transmembrane transport
PGA1_RS14150	COG0747	negative chemotaxis
PGA1_RS14160	COG0745	RESPONSE REGULATOR receiver
PGA1_RS14165	COG0784	Response regulator, receiver
PGA1_RS14165	COG4191	Histidine kinase
PGA1_RS14170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PGA1_RS14190	COG0673	inositol 2-dehydrogenase activity
PGA1_RS14245	COG4251	negative regulation of phosphorylation
PGA1_RS14255	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PGA1_RS14260	COG1984	allophanate hydrolase subunit 2
PGA1_RS14270	COG0121	glutamine amidotransferase
PGA1_RS14280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PGA1_RS14290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PGA1_RS14310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGA1_RS14315	COG0028	Belongs to the TPP enzyme family
PGA1_RS14325	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PGA1_RS14330	COG0280	phosphate acetyltransferase
PGA1_RS14335	COG0372	Belongs to the citrate synthase family
PGA1_RS14340	COG0243	molybdopterin cofactor binding
PGA1_RS14350	COG0437	4 iron, 4 sulfur cluster binding
PGA1_RS14355	COG3302	dmso reductase anchor subunit
PGA1_RS14360	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PGA1_RS14370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PGA1_RS14375	COG0741	lytic transglycosylase activity
PGA1_RS14385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PGA1_RS14385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PGA1_RS14425	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PGA1_RS14430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PGA1_RS14435	COG1846	Transcriptional regulator
PGA1_RS14440	COG0697	spore germination
PGA1_RS14450	COG1051	belongs to the nudix hydrolase family
PGA1_RS14455	COG0446	pyridine nucleotide-disulphide oxidoreductase
PGA1_RS14455	COG1902	pentaerythritol trinitrate reductase activity
PGA1_RS14460	COG0693	protein deglycase activity
PGA1_RS14470	COG2329	Antibiotic biosynthesis monooxygenase
PGA1_RS14485	COG0583	DNA-binding transcription factor activity
PGA1_RS14490	COG2885	chlorophyll binding
PGA1_RS14505	COG1058	Belongs to the CinA family
PGA1_RS14505	COG1546	Belongs to the CinA family
PGA1_RS14510	COG1489	DNA binding
PGA1_RS14515	COG0668	transmembrane transport
PGA1_RS14520	COG0024	Methionine aminopeptidase
PGA1_RS14530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PGA1_RS14535	COG0742	ribosomal rna small subunit methyltransferase
PGA1_RS14545	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PGA1_RS14545	COG0678	peroxiredoxin activity
PGA1_RS14550	COG2154	pterin-4-alpha-carbinolamine dehydratase
PGA1_RS14570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PGA1_RS14595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PGA1_RS14600	COG0347	Belongs to the P(II) protein family
PGA1_RS14605	COG0004	ammonium transporteR
PGA1_RS14615	COG2897	thiosulfate sulfurtransferase activity
PGA1_RS14625	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PGA1_RS14635	COG1396	sequence-specific DNA binding
PGA1_RS14640	COG3135	benzoate transporter
PGA1_RS14645	COG0129	dihydroxy-acid dehydratase activity
PGA1_RS14715	COG1183	phosphatidylcholine synthase activity
PGA1_RS14740	COG0071	Belongs to the small heat shock protein (HSP20) family
PGA1_RS14745	COG3591	Belongs to the peptidase S1B family
PGA1_RS14750	COG3591	Belongs to the peptidase S1B family
PGA1_RS14755	COG0247	lactate metabolic process
PGA1_RS14760	COG0277	FAD linked oxidase domain protein
PGA1_RS14765	COG0277	FAD linked oxidase domain protein
PGA1_RS14780	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PGA1_RS14785	COG0799	negative regulation of ribosome biogenesis
PGA1_RS14790	COG3264	Mechanosensitive ion channel
PGA1_RS14790	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PGA1_RS14800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PGA1_RS14805	COG0066	3-isopropylmalate dehydratase activity
PGA1_RS14825	COG0473	3-isopropylmalate dehydrogenase activity
PGA1_RS14830	COG0697	spore germination
PGA1_RS14845	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PGA1_RS14855	COG0124	histidyl-tRNA synthetase
PGA1_RS14865	COG2217	Heavy metal translocating P-type atpase
PGA1_RS14870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PGA1_RS14880	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PGA1_RS14885	COG0181	hydroxymethylbilane synthase activity
PGA1_RS14895	COG0408	coproporphyrinogen oxidase activity
PGA1_RS14910	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PGA1_RS14925	COG1686	Belongs to the peptidase S11 family
PGA1_RS14945	COG0348	domain, Protein
PGA1_RS14955	COG2010	Cytochrome c
PGA1_RS14980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PGA1_RS14985	COG4172	Belongs to the ABC transporter superfamily
PGA1_RS14990	COG4239	(ABC) transporter, permease
PGA1_RS14995	COG4174	ABC transporter (Permease)
PGA1_RS15000	COG4166	transmembrane transport
PGA1_RS15010	COG1605	Chorismate mutase
PGA1_RS15010	COG0077	Prephenate dehydratase
PGA1_RS15020	COG2816	NAD+ diphosphatase activity
PGA1_RS15025	COG0737	Belongs to the 5'-nucleotidase family
PGA1_RS15055	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PGA1_RS15080	COG0604	alcohol dehydrogenase
PGA1_RS15080	COG1028	Short-chain dehydrogenase reductase Sdr
PGA1_RS15080	COG3321	synthase
PGA1_RS15090	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PGA1_RS15095	COG2326	polyphosphate kinase activity
PGA1_RS15105	COG1522	sequence-specific DNA binding
PGA1_RS15110	COG0686	Belongs to the AlaDH PNT family
PGA1_RS15115	COG1309	transcriptional regulator
PGA1_RS15120	COG2130	NADP-dependent
PGA1_RS15135	COG4948	Mandelate Racemase Muconate Lactonizing
PGA1_RS15145	COG2301	Belongs to the HpcH HpaI aldolase family
PGA1_RS15170	COG0825	malonyl-CoA metabolic process
PGA1_RS15230	COG3093	addiction module antidote protein HigA
PGA1_RS15245	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
PGA1_RS15255	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PGA1_RS15305	COG1175	transmembrane transport
PGA1_RS15310	COG0395	ABC-type sugar transport system, permease component
PGA1_RS15315	COG1653	transport
PGA1_RS15325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PGA1_RS15370	COG2442	InterPro IPR007367
PGA1_RS15405	COG0484	heat shock protein binding
PGA1_RS15455	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PGA1_RS15460	COG1530	ribonuclease E activity
PGA1_RS15470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PGA1_RS15475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PGA1_RS15500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PGA1_RS15515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PGA1_RS15555	COG3842	ATPase activity
PGA1_RS15575	COG1349	DNA-binding transcription factor activity
PGA1_RS15585	COG2379	hydroxypyruvate reductase
PGA1_RS15640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PGA1_RS15655	COG0288	reversible hydration of carbon dioxide
PGA1_RS15665	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PGA1_RS15670	COG0791	NLP P60 protein
PGA1_RS15690	COG1309	transcriptional regulator
PGA1_RS15700	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PGA1_RS15710	COG1671	Belongs to the UPF0178 family
PGA1_RS15725	COG2423	ornithine cyclodeaminase activity
PGA1_RS15730	COG2271	Major facilitator Superfamily
PGA1_RS15735	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PGA1_RS15745	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PGA1_RS15775	COG1131	(ABC) transporter
PGA1_RS15785	COG5001	Diguanylate cyclase
PGA1_RS15785	COG3300	MHYT domain
PGA1_RS15790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PGA1_RS15790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PGA1_RS15800	COG3622	Belongs to the hyi family
PGA1_RS15810	COG0714	Associated with various cellular activities
PGA1_RS15830	COG4953	penicillin-binding protein 1C
PGA1_RS15835	COG2373	Large extracellular alpha-helical protein
PGA1_RS15840	COG0784	Response regulator, receiver
PGA1_RS15840	COG2205	protein histidine kinase activity
PGA1_RS15840	COG5002	protein histidine kinase activity
PGA1_RS15845	COG3022	response to hydroperoxide
PGA1_RS15850	COG0514	ATP-dependent DNA helicase (RecQ)
PGA1_RS15865	COG2270	Major facilitator Superfamily
PGA1_RS15870	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
PGA1_RS15895	COG3191	aminopeptidase activity
PGA1_RS15900	COG3474	cytochrome
PGA1_RS15905	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
PGA1_RS15915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PGA1_RS15920	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PGA1_RS15925	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PGA1_RS15945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGA1_RS15965	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PGA1_RS15970	COG2205	protein histidine kinase activity
PGA1_RS15970	COG2198	Histidine kinase
PGA1_RS15970	COG0784	Response regulator, receiver
PGA1_RS15975	COG1335	isochorismatase
PGA1_RS15980	COG1054	Belongs to the UPF0176 family
PGA1_RS15995	COG3971	2-oxopent-4-enoate hydratase activity
PGA1_RS16000	COG0179	Fumarylacetoacetate (FAA) hydrolase
PGA1_RS16010	COG1012	belongs to the aldehyde dehydrogenase family
PGA1_RS16020	COG5441	Belongs to the UPF0261 family
PGA1_RS16025	COG1012	belongs to the aldehyde dehydrogenase family
PGA1_RS16050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PGA1_RS16090	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PGA1_RS16095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PGA1_RS16100	COG0069	glutamate synthase activity
PGA1_RS16115	COG0542	response to heat
PGA1_RS16120	COG0284	orotidine-5'-phosphate decarboxylase activity
PGA1_RS16130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PGA1_RS16145	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PGA1_RS16150	COG1840	ABC-type Fe3 transport system, periplasmic component
PGA1_RS16160	COG0523	cobalamin synthesis protein
PGA1_RS16165	COG1178	ABC-type Fe3 transport system permease component
PGA1_RS16170	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
PGA1_RS16215	COG4191	Histidine kinase
PGA1_RS16235	COG0625	glutathione transferase activity
PGA1_RS16270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PGA1_RS16275	COG1321	iron dependent repressor
PGA1_RS16275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PGA1_RS16280	COG1121	(ABC) transporter
PGA1_RS16285	COG0803	Belongs to the bacterial solute-binding protein 9 family
PGA1_RS16295	COG1012	belongs to the aldehyde dehydrogenase family
PGA1_RS16300	COG0612	Peptidase, M16
PGA1_RS16305	COG0612	Peptidase, M16
PGA1_RS16315	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PGA1_RS16320	COG0138	bifunctional purine biosynthesis protein purh
PGA1_RS16345	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PGA1_RS16350	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PGA1_RS16360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PGA1_RS16375	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PGA1_RS16380	COG0500	methyltransferase
PGA1_RS16385	COG1185	polyribonucleotide nucleotidyltransferase activity
PGA1_RS16395	COG0450	alkyl hydroperoxide reductase
PGA1_RS16420	COG0564	pseudouridine synthase activity
PGA1_RS16455	COG1280	lysine exporter protein (LysE YggA)
PGA1_RS16470	COG0183	Belongs to the thiolase family
PGA1_RS16480	COG2172	sigma factor antagonist activity
PGA1_RS16485	COG0405	Gamma-glutamyltransferase
PGA1_RS16495	COG3118	belongs to the thioredoxin family
PGA1_RS16505	COG2835	tetraacyldisaccharide 4'-kinase activity
PGA1_RS16510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PGA1_RS16515	COG0154	amidase activity
PGA1_RS16520	COG0436	Aminotransferase
PGA1_RS16525	COG1674	ftsk spoiiie
PGA1_RS16545	COG0745	RESPONSE REGULATOR receiver
PGA1_RS16575	COG0495	leucyl-tRNA aminoacylation
PGA1_RS16590	COG0625	glutathione transferase activity
PGA1_RS16595	COG2081	HI0933 family
PGA1_RS16600	COG1024	Enoyl-CoA hydratase
PGA1_RS16615	COG0312	modulator of DNA gyrase
PGA1_RS16630	COG1663	tetraacyldisaccharide 4'-kinase activity
PGA1_RS16645	COG1194	a g-specific adenine glycosylase
PGA1_RS16650	COG3239	Fatty acid desaturase
PGA1_RS16665	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGA1_RS16695	COG0022	dehydrogenase e1 component
PGA1_RS16700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PGA1_RS16730	COG0583	DNA-binding transcription factor activity
PGA1_RS16735	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PGA1_RS16745	COG0583	DNA-binding transcription factor activity
PGA1_RS16755	COG3448	diguanylate cyclase activity
PGA1_RS16755	COG4175	Glycine betaine
PGA1_RS16760	COG4176	ABC-type proline glycine betaine transport system permease component
PGA1_RS16765	COG2267	carboxylic ester hydrolase activity
PGA1_RS16775	COG0235	Class ii aldolase
PGA1_RS16780	COG3119	arylsulfatase activity
PGA1_RS16815	COG1609	Transcriptional regulator
PGA1_RS16820	COG3214	Protein conserved in bacteria
PGA1_RS16840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PGA1_RS16855	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PGA1_RS16860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PGA1_RS16885	COG0625	glutathione transferase activity
PGA1_RS16895	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
PGA1_RS16900	COG1178	ABC-type Fe3 transport system permease component
PGA1_RS16905	COG4143	(ABC) transporter
PGA1_RS16910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PGA1_RS16915	COG0318	PFAM AMP-dependent synthetase and ligase
PGA1_RS16920	COG0697	spore germination
PGA1_RS16925	COG1846	Transcriptional regulator
PGA1_RS16930	COG1764	response to oxidative stress
PGA1_RS16935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PGA1_RS16940	COG1846	Transcriptional regulator
PGA1_RS16945	COG0745	RESPONSE REGULATOR receiver
PGA1_RS16955	COG1722	exodeoxyribonuclease VII activity
PGA1_RS16960	COG0142	geranyltranstransferase activity
PGA1_RS16965	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PGA1_RS16990	COG1960	acyl-CoA dehydrogenase activity
PGA1_RS17000	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PGA1_RS17005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PGA1_RS17010	COG0776	regulation of translation
PGA1_RS17020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGA1_RS17025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGA1_RS17035	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PGA1_RS17040	COG1063	alcohol dehydrogenase
PGA1_RS17045	COG0156	8-amino-7-oxononanoate synthase activity
PGA1_RS17050	COG1396	sequence-specific DNA binding
PGA1_RS17055	COG0183	Belongs to the thiolase family
PGA1_RS17065	COG1176	ABC-type spermidine putrescine transport system, permease component I
PGA1_RS17075	COG3842	ATPase activity
PGA1_RS17085	COG1802	Transcriptional regulator
PGA1_RS17095	COG3842	ATPase activity
PGA1_RS17100	COG1176	ABC-type spermidine putrescine transport system, permease component I
PGA1_RS17105	COG1177	transmembrane transport
PGA1_RS17115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PGA1_RS17125	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PGA1_RS17130	COG1218	3'(2'),5'-bisphosphate nucleotidase
PGA1_RS17145	COG0443	Heat shock 70 kDa protein
PGA1_RS17150	COG0484	heat shock protein binding
PGA1_RS17155	COG2003	Belongs to the UPF0758 family
PGA1_RS17170	COG0653	protein targeting
PGA1_RS17175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PGA1_RS17180	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PGA1_RS17185	COG0494	nUDIX hydrolase
PGA1_RS17190	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PGA1_RS17205	COG0779	Required for maturation of 30S ribosomal subunits
PGA1_RS17220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PGA1_RS17230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PGA1_RS17240	COG1040	competence protein
PGA1_RS17255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PGA1_RS17275	COG3034	peptidoglycan biosynthetic process
PGA1_RS17285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGA1_RS17290	COG1132	(ABC) transporter
PGA1_RS17295	COG1132	(ABC) transporter
PGA1_RS17300	COG0617	tRNA 3'-terminal CCA addition
PGA1_RS17305	COG0494	nUDIX hydrolase
PGA1_RS17320	COG0745	RESPONSE REGULATOR receiver
PGA1_RS17330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PGA1_RS17340	COG0137	argininosuccinate synthase activity
PGA1_RS17365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGA1_RS17375	COG0280	phosphate acetyltransferase
PGA1_RS17375	COG0281	malic enzyme
PGA1_RS17380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PGA1_RS17385	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PGA1_RS17395	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PGA1_RS17400	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PGA1_RS17405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PGA1_RS17425	COG0357	Ribosomal RNA small subunit methyltransferase G
PGA1_RS17430	COG0445	tRNA wobble uridine modification
PGA1_RS17435	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PGA1_RS17440	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PGA1_RS17445	COG1981	membrane
PGA1_RS17450	COG0424	maF-like protein
PGA1_RS17455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PGA1_RS17460	COG0237	dephospho-CoA kinase activity
PGA1_RS17465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PGA1_RS17470	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PGA1_RS17500	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PGA1_RS17510	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PGA1_RS17545	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PGA1_RS17550	COG3178	'Phosphotransferase
PGA1_RS17555	COG0802	atpase or kinase
PGA1_RS17570	COG1999	signal sequence binding
PGA1_RS17575	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PGA1_RS17580	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
PGA1_RS17590	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PGA1_RS17620	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PGA1_RS17625	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PGA1_RS17655	COG0318	PFAM AMP-dependent synthetase and ligase
PGA1_RS17680	COG1706	bacterial-type flagellum-dependent cell motility
PGA1_RS17685	COG1338	Plays a role in the flagellum-specific transport system
PGA1_RS17690	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PGA1_RS17700	COG1766	The M ring may be actively involved in energy transduction
PGA1_RS17720	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PGA1_RS17735	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PGA1_RS17745	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PGA1_RS17760	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PGA1_RS17770	COG4786	Flagellar basal body rod
PGA1_RS17775	COG4786	Flagellar basal body rod
PGA1_RS17780	COG1987	bacterial-type flagellum assembly
PGA1_RS17785	COG1677	Flagellar hook-basal body complex protein FliE
PGA1_RS17790	COG1558	bacterial-type flagellum-dependent cell motility
PGA1_RS17795	COG1815	bacterial-type flagellum-dependent cell motility
PGA1_RS17805	COG5443	negative regulation of bacterial-type flagellum assembly
PGA1_RS17815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PGA1_RS17835	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PGA1_RS17860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PGA1_RS17865	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PGA1_RS17870	COG1137	ATPase activity
PGA1_RS17885	COG0517	IMP dehydrogenase activity
PGA1_RS17885	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PGA1_RS17890	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PGA1_RS17915	COG1968	undecaprenyl-diphosphatase activity
PGA1_RS17930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PGA1_RS17940	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PGA1_RS17945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PGA1_RS17950	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PGA1_RS17955	COG0560	Phosphoserine phosphatase
PGA1_RS17955	COG3830	Belongs to the UPF0237 family
PGA1_RS17995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PGA1_RS18015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PGA1_RS18025	COG2171	N-acyltransferase activity
PGA1_RS18030	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PGA1_RS18040	COG2986	histidine ammonia-lyase
PGA1_RS18045	COG1228	amidohydrolase
PGA1_RS18065	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PGA1_RS18080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PGA1_RS18085	COG0557	exoribonuclease II activity
PGA1_RS18100	COG2951	lytic endotransglycosylase activity
PGA1_RS18110	COG2226	methyltransferase
PGA1_RS18115	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PGA1_RS18125	COG0268	Binds directly to 16S ribosomal RNA
PGA1_RS18135	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PGA1_RS18555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PGA1_RS18910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PGA1_RS18990	COG0037	tRNA processing
PGA1_RS19195	COG2217	Heavy metal translocating P-type atpase
PGA1_RS19300	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PGA1_RS19610	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PGA1_RS19750	COG0587	DNA-directed DNA polymerase activity
PGA1_RS19845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY