locus-tag	class	description
PhaeoP66_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PhaeoP66_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PhaeoP66_RS00030	COG0431	NADPH-dependent FMN reductase
PhaeoP66_RS00050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PhaeoP66_RS00055	COG0473	3-isopropylmalate dehydrogenase activity
PhaeoP66_RS00060	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS00065	COG1522	sequence-specific DNA binding
PhaeoP66_RS00105	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PhaeoP66_RS00105	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PhaeoP66_RS00120	COG0277	FAD linked oxidase domain protein
PhaeoP66_RS00125	COG0754	glutathionylspermidine amidase activity
PhaeoP66_RS00250	COG3448	diguanylate cyclase activity
PhaeoP66_RS00250	COG4175	Glycine betaine
PhaeoP66_RS00255	COG4176	ABC-type proline glycine betaine transport system permease component
PhaeoP66_RS00270	COG0587	DNA-directed DNA polymerase activity
PhaeoP66_RS00285	COG3046	protein related to deoxyribodipyrimidine photolyase
PhaeoP66_RS00290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PhaeoP66_RS00300	COG0625	glutathione transferase activity
PhaeoP66_RS00305	COG0346	lactoylglutathione lyase activity
PhaeoP66_RS00325	COG0179	Fumarylacetoacetate (FAA) hydrolase
PhaeoP66_RS00330	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PhaeoP66_RS00355	COG0489	protein tyrosine kinase activity
PhaeoP66_RS00355	COG2151	metal-sulfur cluster biosynthetic enzyme
PhaeoP66_RS00360	COG0254	rRNA binding
PhaeoP66_RS00365	COG0335	large ribosomal subunit rRNA binding
PhaeoP66_RS00370	COG0336	Belongs to the RNA methyltransferase TrmD family
PhaeoP66_RS00380	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PhaeoP66_RS00385	COG0778	Nitroreductase
PhaeoP66_RS00390	COG0228	four-way junction DNA binding
PhaeoP66_RS00405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PhaeoP66_RS00415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PhaeoP66_RS00455	COG0356	it plays a direct role in the translocation of protons across the membrane
PhaeoP66_RS00460	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PhaeoP66_RS00465	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PhaeoP66_RS00470	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PhaeoP66_RS00480	COG2186	Transcriptional regulator
PhaeoP66_RS00510	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PhaeoP66_RS00520	COG0435	Glutathione S-transferase
PhaeoP66_RS00530	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PhaeoP66_RS00535	COG0242	peptide deformylase activity
PhaeoP66_RS00540	COG0242	peptide deformylase activity
PhaeoP66_RS00545	COG0242	peptide deformylase activity
PhaeoP66_RS00550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PhaeoP66_RS00560	COG2860	membrane
PhaeoP66_RS00565	COG0328	RNA-DNA hybrid ribonuclease activity
PhaeoP66_RS00585	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PhaeoP66_RS00595	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PhaeoP66_RS00600	COG1758	RNA polymerase activity
PhaeoP66_RS00615	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PhaeoP66_RS00620	COG0736	holo-[acyl-carrier-protein] synthase activity
PhaeoP66_RS00625	COG0681	Belongs to the peptidase S26 family
PhaeoP66_RS00630	COG0571	ribonuclease III activity
PhaeoP66_RS00635	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PhaeoP66_RS00645	COG1381	Involved in DNA repair and RecF pathway recombination
PhaeoP66_RS00665	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PhaeoP66_RS00670	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PhaeoP66_RS00675	COG0745	RESPONSE REGULATOR receiver
PhaeoP66_RS00680	COG2205	protein histidine kinase activity
PhaeoP66_RS00685	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PhaeoP66_RS00690	COG1660	Displays ATPase and GTPase activities
PhaeoP66_RS00700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PhaeoP66_RS00710	COG1250	3-hydroxyacyl-CoA dehydrogenase
PhaeoP66_RS00730	COG2096	Adenosyltransferase
PhaeoP66_RS00740	COG0300	oxidoreductase activity
PhaeoP66_RS00750	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PhaeoP66_RS00760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PhaeoP66_RS00785	COG0250	Participates in transcription elongation, termination and antitermination
PhaeoP66_RS00795	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PhaeoP66_RS00800	COG0081	regulation of translation
PhaeoP66_RS00805	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PhaeoP66_RS00810	COG0222	ribosome binding
PhaeoP66_RS00815	COG0085	RNA polymerase activity
PhaeoP66_RS00820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PhaeoP66_RS00835	COG0435	Glutathione S-transferase
PhaeoP66_RS00840	COG1335	isochorismatase
PhaeoP66_RS00850	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS00875	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PhaeoP66_RS00880	COG0049	tRNA binding
PhaeoP66_RS00885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PhaeoP66_RS00890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PhaeoP66_RS00900	COG0051	transcription antitermination factor activity, RNA binding
PhaeoP66_RS00905	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PhaeoP66_RS00910	COG0088	Forms part of the polypeptide exit tunnel
PhaeoP66_RS00915	COG0089	rRNA binding
PhaeoP66_RS00925	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PhaeoP66_RS00930	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PhaeoP66_RS00935	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PhaeoP66_RS00940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PhaeoP66_RS00945	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PhaeoP66_RS00970	COG0255	Belongs to the universal ribosomal protein uL29 family
PhaeoP66_RS00975	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PhaeoP66_RS00980	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PhaeoP66_RS00985	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PhaeoP66_RS00990	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PhaeoP66_RS00995	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PhaeoP66_RS01000	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PhaeoP66_RS01005	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PhaeoP66_RS01010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PhaeoP66_RS01015	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PhaeoP66_RS01020	COG1841	ribosomal large subunit assembly
PhaeoP66_RS01035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PhaeoP66_RS01050	COG0200	Binds to the 23S rRNA
PhaeoP66_RS01055	COG0201	protein transport
PhaeoP66_RS01060	COG0563	adenylate kinase activity
PhaeoP66_RS01065	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PhaeoP66_RS01070	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PhaeoP66_RS01075	COG0202	RNA polymerase activity
PhaeoP66_RS01080	COG0203	ribosomal protein L17
PhaeoP66_RS01085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PhaeoP66_RS01090	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PhaeoP66_RS01095	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PhaeoP66_RS01105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PhaeoP66_RS01115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PhaeoP66_RS01120	COG4597	amino acid ABC transporter
PhaeoP66_RS01125	COG0765	amino acid transport
PhaeoP66_RS01130	COG1126	abc transporter atp-binding protein
PhaeoP66_RS01150	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PhaeoP66_RS01155	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS01160	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PhaeoP66_RS01170	COG0706	membrane insertase activity
PhaeoP66_RS01180	COG0037	tRNA processing
PhaeoP66_RS01190	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PhaeoP66_RS01195	COG0594	ribonuclease P activity
PhaeoP66_RS01200	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PhaeoP66_RS01220	COG4191	Histidine kinase
PhaeoP66_RS01235	COG0477	Major facilitator Superfamily
PhaeoP66_RS01250	COG0189	ligase activity
PhaeoP66_RS01250	COG4067	protein conserved in archaea
PhaeoP66_RS01255	COG0189	ligase activity
PhaeoP66_RS01295	COG0411	ABC transporter
PhaeoP66_RS01315	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS01325	COG2207	Transcriptional regulator
PhaeoP66_RS01365	COG0825	malonyl-CoA metabolic process
PhaeoP66_RS01390	COG2301	Belongs to the HpcH HpaI aldolase family
PhaeoP66_RS01400	COG4948	Mandelate Racemase Muconate Lactonizing
PhaeoP66_RS01415	COG2130	NADP-dependent
PhaeoP66_RS01420	COG1309	transcriptional regulator
PhaeoP66_RS01425	COG0686	Belongs to the AlaDH PNT family
PhaeoP66_RS01430	COG1522	sequence-specific DNA binding
PhaeoP66_RS01440	COG2326	polyphosphate kinase activity
PhaeoP66_RS01445	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PhaeoP66_RS01455	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS01455	COG0604	alcohol dehydrogenase
PhaeoP66_RS01455	COG3321	synthase
PhaeoP66_RS01480	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PhaeoP66_RS01515	COG0737	Belongs to the 5'-nucleotidase family
PhaeoP66_RS01520	COG2816	NAD+ diphosphatase activity
PhaeoP66_RS01530	COG1605	Chorismate mutase
PhaeoP66_RS01530	COG0077	Prephenate dehydratase
PhaeoP66_RS01540	COG4166	transmembrane transport
PhaeoP66_RS01545	COG4174	ABC transporter (Permease)
PhaeoP66_RS01550	COG4239	(ABC) transporter, permease
PhaeoP66_RS01555	COG4172	Belongs to the ABC transporter superfamily
PhaeoP66_RS01560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PhaeoP66_RS01585	COG2010	Cytochrome c
PhaeoP66_RS01595	COG0348	domain, Protein
PhaeoP66_RS01615	COG1686	Belongs to the peptidase S11 family
PhaeoP66_RS01630	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PhaeoP66_RS01645	COG0408	coproporphyrinogen oxidase activity
PhaeoP66_RS01655	COG0181	hydroxymethylbilane synthase activity
PhaeoP66_RS01660	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PhaeoP66_RS01665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PhaeoP66_RS01670	COG2217	Heavy metal translocating P-type atpase
PhaeoP66_RS01680	COG0124	histidyl-tRNA synthetase
PhaeoP66_RS01690	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PhaeoP66_RS01705	COG0697	spore germination
PhaeoP66_RS01710	COG0473	3-isopropylmalate dehydrogenase activity
PhaeoP66_RS01730	COG0066	3-isopropylmalate dehydratase activity
PhaeoP66_RS01735	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PhaeoP66_RS01745	COG3264	Mechanosensitive ion channel
PhaeoP66_RS01745	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PhaeoP66_RS01750	COG0799	negative regulation of ribosome biogenesis
PhaeoP66_RS01755	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PhaeoP66_RS01770	COG0277	FAD linked oxidase domain protein
PhaeoP66_RS01775	COG0277	FAD linked oxidase domain protein
PhaeoP66_RS01780	COG0247	lactate metabolic process
PhaeoP66_RS01785	COG3591	Belongs to the peptidase S1B family
PhaeoP66_RS01790	COG3591	Belongs to the peptidase S1B family
PhaeoP66_RS01795	COG0071	Belongs to the small heat shock protein (HSP20) family
PhaeoP66_RS01820	COG1183	phosphatidylcholine synthase activity
PhaeoP66_RS01885	COG0129	dihydroxy-acid dehydratase activity
PhaeoP66_RS01890	COG3135	benzoate transporter
PhaeoP66_RS01895	COG1396	sequence-specific DNA binding
PhaeoP66_RS01905	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PhaeoP66_RS01915	COG2897	thiosulfate sulfurtransferase activity
PhaeoP66_RS01925	COG0004	ammonium transporteR
PhaeoP66_RS01930	COG0347	Belongs to the P(II) protein family
PhaeoP66_RS01935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PhaeoP66_RS01960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PhaeoP66_RS01980	COG2154	pterin-4-alpha-carbinolamine dehydratase
PhaeoP66_RS01985	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PhaeoP66_RS01985	COG0678	peroxiredoxin activity
PhaeoP66_RS01995	COG0742	ribosomal rna small subunit methyltransferase
PhaeoP66_RS02000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PhaeoP66_RS02005	COG0024	Methionine aminopeptidase
PhaeoP66_RS02010	COG0668	transmembrane transport
PhaeoP66_RS02015	COG1489	DNA binding
PhaeoP66_RS02020	COG1546	Belongs to the CinA family
PhaeoP66_RS02020	COG1058	Belongs to the CinA family
PhaeoP66_RS02035	COG2885	chlorophyll binding
PhaeoP66_RS02040	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS02055	COG2329	Antibiotic biosynthesis monooxygenase
PhaeoP66_RS02065	COG0693	protein deglycase activity
PhaeoP66_RS02070	COG1902	pentaerythritol trinitrate reductase activity
PhaeoP66_RS02070	COG0446	pyridine nucleotide-disulphide oxidoreductase
PhaeoP66_RS02075	COG1051	belongs to the nudix hydrolase family
PhaeoP66_RS02085	COG0697	spore germination
PhaeoP66_RS02090	COG1846	Transcriptional regulator
PhaeoP66_RS02095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PhaeoP66_RS02100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PhaeoP66_RS02150	COG0741	lytic transglycosylase activity
PhaeoP66_RS02155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PhaeoP66_RS02165	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PhaeoP66_RS02170	COG3302	dmso reductase anchor subunit
PhaeoP66_RS02175	COG0437	4 iron, 4 sulfur cluster binding
PhaeoP66_RS02180	COG0243	molybdopterin cofactor binding
PhaeoP66_RS02185	COG0372	Belongs to the citrate synthase family
PhaeoP66_RS02190	COG0280	phosphate acetyltransferase
PhaeoP66_RS02195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PhaeoP66_RS02205	COG0028	Belongs to the TPP enzyme family
PhaeoP66_RS02210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PhaeoP66_RS02230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PhaeoP66_RS02240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PhaeoP66_RS02250	COG0121	glutamine amidotransferase
PhaeoP66_RS02260	COG1984	allophanate hydrolase subunit 2
PhaeoP66_RS02265	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PhaeoP66_RS02275	COG4251	negative regulation of phosphorylation
PhaeoP66_RS02315	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS02320	COG0625	glutathione transferase activity
PhaeoP66_RS02330	COG1942	4-Oxalocrotonate Tautomerase
PhaeoP66_RS02340	COG1309	transcriptional regulator
PhaeoP66_RS02345	COG0784	Response regulator, receiver
PhaeoP66_RS02345	COG4191	Histidine kinase
PhaeoP66_RS02350	COG0745	RESPONSE REGULATOR receiver
PhaeoP66_RS02360	COG0747	negative chemotaxis
PhaeoP66_RS02370	COG0601	transmembrane transport
PhaeoP66_RS02375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PhaeoP66_RS02380	COG0444	Belongs to the ABC transporter superfamily
PhaeoP66_RS02410	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PhaeoP66_RS02420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PhaeoP66_RS02460	COG0405	Gamma-glutamyltransferase
PhaeoP66_RS02465	COG0277	FAD linked oxidase domain protein
PhaeoP66_RS02495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PhaeoP66_RS02505	COG1079	Belongs to the binding-protein-dependent transport system permease family
PhaeoP66_RS02515	COG4603	Belongs to the binding-protein-dependent transport system permease family
PhaeoP66_RS02520	COG3845	ABC transporter
PhaeoP66_RS02530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PhaeoP66_RS02570	COG1072	(Pantothenic acid kinase))
PhaeoP66_RS02580	COG0800	Aldolase
PhaeoP66_RS02585	COG0129	dihydroxy-acid dehydratase activity
PhaeoP66_RS02590	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PhaeoP66_RS02595	COG0166	Belongs to the GPI family
PhaeoP66_RS02605	COG0673	inositol 2-dehydrogenase activity
PhaeoP66_RS02610	COG0395	ABC-type sugar transport system, permease component
PhaeoP66_RS02615	COG1175	transmembrane transport
PhaeoP66_RS02625	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PhaeoP66_RS02635	COG2188	Transcriptional regulator
PhaeoP66_RS02640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PhaeoP66_RS02645	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PhaeoP66_RS02650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PhaeoP66_RS02685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PhaeoP66_RS02690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PhaeoP66_RS02700	COG3842	ATPase activity
PhaeoP66_RS02720	COG0489	protein tyrosine kinase activity
PhaeoP66_RS02755	COG3383	formate dehydrogenase (NAD+) activity
PhaeoP66_RS02755	COG0243	molybdopterin cofactor binding
PhaeoP66_RS02760	COG0437	4 iron, 4 sulfur cluster binding
PhaeoP66_RS02775	COG2204	response regulator
PhaeoP66_RS02780	COG3852	Histidine kinase
PhaeoP66_RS02785	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS02790	COG4221	oxidoreductase activity
PhaeoP66_RS02810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PhaeoP66_RS02825	COG1595	DNA-templated transcription, initiation
PhaeoP66_RS02830	COG3806	Anti-sigma factor
PhaeoP66_RS02845	COG0840	transmembrane signaling receptor activity
PhaeoP66_RS02860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PhaeoP66_RS02875	COG1609	Transcriptional regulator
PhaeoP66_RS02880	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS02890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PhaeoP66_RS02900	COG0395	ABC-type sugar transport system, permease component
PhaeoP66_RS02905	COG1175	transmembrane transport
PhaeoP66_RS02930	COG2197	response regulator
PhaeoP66_RS02935	COG4251	negative regulation of phosphorylation
PhaeoP66_RS02945	COG5002	protein histidine kinase activity
PhaeoP66_RS02950	COG0745	RESPONSE REGULATOR receiver
PhaeoP66_RS02960	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS02965	COG2175	clavaminate synthase activity
PhaeoP66_RS02980	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS02985	COG0174	glutamine synthetase
PhaeoP66_RS03030	COG0784	Response regulator, receiver
PhaeoP66_RS03050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PhaeoP66_RS03075	COG3237	CsbD-like
PhaeoP66_RS03110	COG0402	S-adenosylhomocysteine deaminase activity
PhaeoP66_RS03115	COG1079	Belongs to the binding-protein-dependent transport system permease family
PhaeoP66_RS03120	COG4603	Belongs to the binding-protein-dependent transport system permease family
PhaeoP66_RS03125	COG3845	ABC transporter
PhaeoP66_RS03135	COG0251	oxidation-reduction process
PhaeoP66_RS03140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PhaeoP66_RS03150	COG1120	ATPase activity
PhaeoP66_RS03160	COG3327	negative regulation of DNA-templated transcription, initiation
PhaeoP66_RS03165	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS03165	COG2030	dehydratase
PhaeoP66_RS03170	COG1024	Enoyl-CoA hydratase
PhaeoP66_RS03175	COG2050	protein possibly involved in aromatic compounds catabolism
PhaeoP66_RS03185	COG1309	transcriptional regulator
PhaeoP66_RS03190	COG1278	Cold shock
PhaeoP66_RS03195	COG0180	Tryptophanyl-tRNA synthetase
PhaeoP66_RS03210	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PhaeoP66_RS03220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PhaeoP66_RS03225	COG0792	nuclease activity
PhaeoP66_RS03235	COG0606	chelatase, subunit chli
PhaeoP66_RS03265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PhaeoP66_RS03270	COG0756	dUTP diphosphatase activity
PhaeoP66_RS03275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PhaeoP66_RS03280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PhaeoP66_RS03285	COG0765	amino acid transport
PhaeoP66_RS03290	COG0339	signal peptide processing
PhaeoP66_RS03300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PhaeoP66_RS03315	COG0772	Belongs to the SEDS family
PhaeoP66_RS03320	COG0768	penicillin binding
PhaeoP66_RS03340	COG2957	Belongs to the agmatine deiminase family
PhaeoP66_RS03345	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PhaeoP66_RS03350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PhaeoP66_RS03365	COG3706	GGDEF domain
PhaeoP66_RS03370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PhaeoP66_RS03385	COG1959	2 iron, 2 sulfur cluster binding
PhaeoP66_RS03395	COG4181	ATPase activity
PhaeoP66_RS03405	COG1278	Cold shock
PhaeoP66_RS03410	COG1376	ErfK ybiS ycfS ynhG family protein
PhaeoP66_RS03450	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PhaeoP66_RS03475	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
PhaeoP66_RS03520	COG0556	nucleotide-excision repair
PhaeoP66_RS03590	COG1404	Belongs to the peptidase S8 family
PhaeoP66_RS03595	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PhaeoP66_RS03690	COG1846	Transcriptional regulator
PhaeoP66_RS03695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PhaeoP66_RS03700	COG4774	siderophore transport
PhaeoP66_RS03720	COG0811	peptide transport
PhaeoP66_RS03730	COG1120	ATPase activity
PhaeoP66_RS03735	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PhaeoP66_RS03740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PhaeoP66_RS03760	COG0488	(ABC) transporter
PhaeoP66_RS03775	COG0840	transmembrane signaling receptor activity
PhaeoP66_RS03785	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS03790	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
PhaeoP66_RS03795	COG3383	formate dehydrogenase (NAD+) activity
PhaeoP66_RS03810	COG0446	pyridine nucleotide-disulphide oxidoreductase
PhaeoP66_RS03810	COG1902	pentaerythritol trinitrate reductase activity
PhaeoP66_RS03855	COG0179	Fumarylacetoacetate (FAA) hydrolase
PhaeoP66_RS03885	COG3713	MltA-interacting MipA family protein
PhaeoP66_RS03890	COG0179	Fumarylacetoacetate (FAA) hydrolase
PhaeoP66_RS03905	COG1902	pentaerythritol trinitrate reductase activity
PhaeoP66_RS03905	COG0446	pyridine nucleotide-disulphide oxidoreductase
PhaeoP66_RS03915	COG0543	2 iron, 2 sulfur cluster binding
PhaeoP66_RS03915	COG0633	Ferredoxin
PhaeoP66_RS03920	COG0318	PFAM AMP-dependent synthetase and ligase
PhaeoP66_RS03930	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS03935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PhaeoP66_RS03940	COG4597	amino acid ABC transporter
PhaeoP66_RS03945	COG0765	amino acid transport
PhaeoP66_RS03950	COG1126	abc transporter atp-binding protein
PhaeoP66_RS03960	COG4172	Belongs to the ABC transporter superfamily
PhaeoP66_RS03965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PhaeoP66_RS03975	COG0747	negative chemotaxis
PhaeoP66_RS04000	COG3048	D-serine ammonia-lyase activity
PhaeoP66_RS04005	COG1846	Transcriptional regulator
PhaeoP66_RS04010	COG0753	catalase activity
PhaeoP66_RS04065	COG1959	2 iron, 2 sulfur cluster binding
PhaeoP66_RS04075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PhaeoP66_RS04090	COG2116	formate transmembrane transporter activity
PhaeoP66_RS04110	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PhaeoP66_RS04120	COG1522	sequence-specific DNA binding
PhaeoP66_RS04125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PhaeoP66_RS04130	COG0287	Prephenate dehydrogenase
PhaeoP66_RS04145	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
PhaeoP66_RS04175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PhaeoP66_RS04185	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PhaeoP66_RS04190	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PhaeoP66_RS04195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PhaeoP66_RS04200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PhaeoP66_RS04205	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PhaeoP66_RS04225	COG0596	Alpha beta hydrolase
PhaeoP66_RS04245	COG2983	Belongs to the UPF0260 family
PhaeoP66_RS04250	COG0196	riboflavin kinase activity
PhaeoP66_RS04255	COG2030	dehydratase
PhaeoP66_RS04270	COG1227	inorganic diphosphatase activity
PhaeoP66_RS04280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PhaeoP66_RS04285	COG0459	protein refolding
PhaeoP66_RS04290	COG3153	acetyltransferase
PhaeoP66_RS04305	COG3454	Phosphonate metabolism
PhaeoP66_RS04310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PhaeoP66_RS04315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PhaeoP66_RS04325	COG0071	Belongs to the small heat shock protein (HSP20) family
PhaeoP66_RS04335	COG0384	phenazine biosynthesis protein PhzF
PhaeoP66_RS04345	COG0529	Catalyzes the synthesis of activated sulfate
PhaeoP66_RS04345	COG2046	Belongs to the sulfate adenylyltransferase family
PhaeoP66_RS04355	COG0492	ferredoxin-NADP+ reductase activity
PhaeoP66_RS04360	COG1522	sequence-specific DNA binding
PhaeoP66_RS04370	COG1496	oxidoreductase activity
PhaeoP66_RS04380	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PhaeoP66_RS04400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PhaeoP66_RS04410	COG1435	thymidine kinase activity
PhaeoP66_RS04420	COG0431	NADPH-dependent FMN reductase
PhaeoP66_RS04430	COG1846	Transcriptional regulator
PhaeoP66_RS04445	COG3591	Belongs to the peptidase S1B family
PhaeoP66_RS04450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PhaeoP66_RS04460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PhaeoP66_RS04465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PhaeoP66_RS04465	COG0512	Glutamine amidotransferase of anthranilate synthase
PhaeoP66_RS04475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PhaeoP66_RS04500	COG0346	lactoylglutathione lyase activity
PhaeoP66_RS04515	COG0778	Nitroreductase
PhaeoP66_RS04520	COG1872	DUF167
PhaeoP66_RS04535	COG1739	Uncharacterized protein family UPF0029
PhaeoP66_RS04560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PhaeoP66_RS04575	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PhaeoP66_RS04600	COG0625	glutathione transferase activity
PhaeoP66_RS04615	COG0842	Transport permease protein
PhaeoP66_RS04630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PhaeoP66_RS04635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PhaeoP66_RS04640	COG0306	phosphate transporter
PhaeoP66_RS04650	COG1643	Atp-dependent helicase
PhaeoP66_RS04655	COG1703	isobutyryl-CoA mutase activity
PhaeoP66_RS04660	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PhaeoP66_RS04675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PhaeoP66_RS04680	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS04700	COG0481	GTPase activity
PhaeoP66_RS04710	COG5510	response to toxic substance
PhaeoP66_RS04715	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PhaeoP66_RS04720	COG2824	Alkylphosphonate utilization operon protein PhnA
PhaeoP66_RS04725	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PhaeoP66_RS04740	COG1492	cobalamin metabolic process
PhaeoP66_RS04750	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PhaeoP66_RS04760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PhaeoP66_RS04765	COG1132	(ABC) transporter
PhaeoP66_RS04770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PhaeoP66_RS04775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PhaeoP66_RS04780	COG1024	Enoyl-CoA hydratase
PhaeoP66_RS04785	COG3588	fructose-bisphosphate aldolase
PhaeoP66_RS04790	COG0504	CTP synthase activity
PhaeoP66_RS04825	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS04835	COG0642	Histidine kinase
PhaeoP66_RS04840	COG0745	RESPONSE REGULATOR receiver
PhaeoP66_RS04875	COG2207	Transcriptional regulator
PhaeoP66_RS04915	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PhaeoP66_RS04940	COG1760	l-serine dehydratase
PhaeoP66_RS04945	COG0625	glutathione transferase activity
PhaeoP66_RS04955	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PhaeoP66_RS04975	COG0330	HflC and HflK could
PhaeoP66_RS05015	COG3781	membrane
PhaeoP66_RS05025	COG1570	exodeoxyribonuclease VII activity
PhaeoP66_RS05040	COG0552	protein localization to endoplasmic reticulum
PhaeoP66_RS05050	COG2917	probably involved in intracellular septation
PhaeoP66_RS05060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PhaeoP66_RS05315	COG1469	GTP cyclohydrolase I activity
PhaeoP66_RS05325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PhaeoP66_RS05330	COG0527	aspartate kinase activity
PhaeoP66_RS05335	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PhaeoP66_RS05345	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS05355	COG1024	Enoyl-CoA hydratase
PhaeoP66_RS05385	COG1349	DNA-binding transcription factor activity
PhaeoP66_RS05405	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS05410	COG0174	glutamine synthetase
PhaeoP66_RS05445	COG4175	Glycine betaine
PhaeoP66_RS05445	COG3448	diguanylate cyclase activity
PhaeoP66_RS05455	COG1349	DNA-binding transcription factor activity
PhaeoP66_RS05475	COG0784	Response regulator, receiver
PhaeoP66_RS05475	COG2198	Histidine kinase
PhaeoP66_RS05475	COG5002	protein histidine kinase activity
PhaeoP66_RS05500	COG1132	(ABC) transporter
PhaeoP66_RS05505	COG0318	PFAM AMP-dependent synthetase and ligase
PhaeoP66_RS05530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PhaeoP66_RS05535	COG0601	transmembrane transport
PhaeoP66_RS05545	COG1490	D-aminoacyl-tRNA deacylase activity
PhaeoP66_RS05550	COG0778	Nitroreductase
PhaeoP66_RS05575	COG3853	Toxic anion resistance protein (TelA)
PhaeoP66_RS05585	COG1187	pseudouridine synthase activity
PhaeoP66_RS05590	COG0590	tRNA wobble adenosine to inosine editing
PhaeoP66_RS05595	COG2818	Glycosylase
PhaeoP66_RS05600	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PhaeoP66_RS05605	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PhaeoP66_RS05610	COG0154	amidase activity
PhaeoP66_RS05630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PhaeoP66_RS05640	COG0670	Belongs to the BI1 family
PhaeoP66_RS05655	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS05660	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS05660	COG3321	synthase
PhaeoP66_RS05660	COG0604	alcohol dehydrogenase
PhaeoP66_RS05665	COG1396	sequence-specific DNA binding
PhaeoP66_RS05670	COG0483	inositol monophosphate 1-phosphatase activity
PhaeoP66_RS05680	COG0402	S-adenosylhomocysteine deaminase activity
PhaeoP66_RS05685	COG2239	Acts as a magnesium transporter
PhaeoP66_RS05690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PhaeoP66_RS05695	COG1692	metallophosphoesterase
PhaeoP66_RS05700	COG3273	potassium ion transport
PhaeoP66_RS05700	COG0471	metal ion transport
PhaeoP66_RS05710	COG3273	potassium ion transport
PhaeoP66_RS05710	COG0471	metal ion transport
PhaeoP66_RS05715	COG0217	transcriptional regulatory protein
PhaeoP66_RS05720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PhaeoP66_RS05720	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PhaeoP66_RS05740	COG0697	spore germination
PhaeoP66_RS05750	COG1309	transcriptional regulator
PhaeoP66_RS05760	COG3119	arylsulfatase activity
PhaeoP66_RS05785	COG3800	Transcriptional regulator
PhaeoP66_RS05785	COG1396	sequence-specific DNA binding
PhaeoP66_RS05795	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
PhaeoP66_RS05800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PhaeoP66_RS05825	COG4770	biotin carboxylase activity
PhaeoP66_RS05845	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PhaeoP66_RS05845	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PhaeoP66_RS05860	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PhaeoP66_RS05875	COG0248	Ppx GppA phosphatase
PhaeoP66_RS05885	COG0628	permease
PhaeoP66_RS05890	COG0442	prolyl-tRNA aminoacylation
PhaeoP66_RS05900	COG1136	(ABC) transporter
PhaeoP66_RS05910	COG0243	molybdopterin cofactor binding
PhaeoP66_RS05930	COG0187	DNA topoisomerase II activity
PhaeoP66_RS05950	COG0534	Mate efflux family protein
PhaeoP66_RS05955	COG0183	Belongs to the thiolase family
PhaeoP66_RS05960	COG1024	Enoyl-CoA hydratase
PhaeoP66_RS05960	COG1250	3-hydroxyacyl-CoA dehydrogenase
PhaeoP66_RS05970	COG0318	PFAM AMP-dependent synthetase and ligase
PhaeoP66_RS05975	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS05980	COG4175	Glycine betaine
PhaeoP66_RS05980	COG0517	IMP dehydrogenase activity
PhaeoP66_RS05985	COG4176	ABC-type proline glycine betaine transport system permease component
PhaeoP66_RS05995	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PhaeoP66_RS06000	COG0252	asparaginase activity
PhaeoP66_RS06005	COG2423	ornithine cyclodeaminase activity
PhaeoP66_RS06015	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS06025	COG1280	lysine exporter protein (LysE YggA)
PhaeoP66_RS06035	COG1349	DNA-binding transcription factor activity
PhaeoP66_RS06040	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS06085	COG1846	Transcriptional regulator
PhaeoP66_RS06090	COG0346	lactoylglutathione lyase activity
PhaeoP66_RS06105	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PhaeoP66_RS06135	COG1802	Transcriptional regulator
PhaeoP66_RS06145	COG2267	carboxylic ester hydrolase activity
PhaeoP66_RS06155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PhaeoP66_RS06160	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS06165	COG1278	Cold shock
PhaeoP66_RS06170	COG1393	Belongs to the ArsC family
PhaeoP66_RS06190	COG3220	belongs to the UPF0276 family
PhaeoP66_RS06200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PhaeoP66_RS06235	COG3243	poly(R)-hydroxyalkanoic acid synthase
PhaeoP66_RS06250	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PhaeoP66_RS06275	COG0840	transmembrane signaling receptor activity
PhaeoP66_RS06280	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PhaeoP66_RS06290	COG3443	Belongs to the bacterial solute-binding protein 9 family
PhaeoP66_RS06315	COG0175	sulfate reduction
PhaeoP66_RS06320	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PhaeoP66_RS06330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PhaeoP66_RS06330	COG1648	precorrin-2 dehydrogenase activity
PhaeoP66_RS06335	COG1522	sequence-specific DNA binding
PhaeoP66_RS06355	COG2204	response regulator
PhaeoP66_RS06360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PhaeoP66_RS06365	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PhaeoP66_RS06370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PhaeoP66_RS06375	COG0149	triose-phosphate isomerase activity
PhaeoP66_RS06380	COG0316	Belongs to the HesB IscA family
PhaeoP66_RS06390	COG2151	metal-sulfur cluster biosynthetic enzyme
PhaeoP66_RS06395	COG0523	cobalamin synthesis protein
PhaeoP66_RS06415	COG0343	queuine tRNA-ribosyltransferase activity
PhaeoP66_RS06430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PhaeoP66_RS06460	COG1522	sequence-specific DNA binding
PhaeoP66_RS06575	COG0406	alpha-ribazole phosphatase activity
PhaeoP66_RS06610	COG0156	8-amino-7-oxononanoate synthase activity
PhaeoP66_RS06620	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PhaeoP66_RS06635	COG0436	Aminotransferase
PhaeoP66_RS06640	COG0860	N-Acetylmuramoyl-L-alanine amidase
PhaeoP66_RS06645	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PhaeoP66_RS06650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PhaeoP66_RS06675	COG0440	acetolactate synthase activity
PhaeoP66_RS06680	COG0028	Belongs to the TPP enzyme family
PhaeoP66_RS06705	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PhaeoP66_RS06710	COG0346	lactoylglutathione lyase activity
PhaeoP66_RS06715	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PhaeoP66_RS06760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PhaeoP66_RS06785	COG0277	FAD linked oxidase domain protein
PhaeoP66_RS06790	COG1177	transmembrane transport
PhaeoP66_RS06795	COG1176	ABC-type spermidine putrescine transport system, permease component I
PhaeoP66_RS06805	COG3842	ATPase activity
PhaeoP66_RS06810	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS06820	COG0523	cobalamin synthesis protein
PhaeoP66_RS06830	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PhaeoP66_RS06840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PhaeoP66_RS06850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PhaeoP66_RS06860	COG3956	TIGRFAM MazG family protein
PhaeoP66_RS06865	COG1473	amidohydrolase
PhaeoP66_RS06870	COG0010	Belongs to the arginase family
PhaeoP66_RS06890	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PhaeoP66_RS06895	COG2890	protein-(glutamine-N5) methyltransferase activity
PhaeoP66_RS06905	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PhaeoP66_RS06910	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PhaeoP66_RS06915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PhaeoP66_RS06935	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PhaeoP66_RS06950	COG2095	MarC family integral membrane protein
PhaeoP66_RS06955	COG0488	(ABC) transporter
PhaeoP66_RS06960	COG0105	UTP biosynthetic process
PhaeoP66_RS06970	COG0401	homolog of Blt101
PhaeoP66_RS07000	COG1271	oxidase subunit
PhaeoP66_RS07005	COG1294	oxidase, subunit
PhaeoP66_RS07015	COG2197	response regulator
PhaeoP66_RS07040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PhaeoP66_RS07045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PhaeoP66_RS07050	COG0730	response to heat
PhaeoP66_RS07065	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PhaeoP66_RS07070	COG4235	cytochrome complex assembly
PhaeoP66_RS07075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PhaeoP66_RS07085	COG0446	pyridine nucleotide-disulphide oxidoreductase
PhaeoP66_RS07085	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PhaeoP66_RS07130	COG5265	(ABC) transporter
PhaeoP66_RS07140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PhaeoP66_RS07160	COG1160	GTP binding
PhaeoP66_RS07165	COG3239	Fatty acid desaturase
PhaeoP66_RS07175	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PhaeoP66_RS07185	COG1862	Preprotein translocase
PhaeoP66_RS07190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PhaeoP66_RS07195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PhaeoP66_RS07200	COG3737	Protein of unknown function (DUF498/DUF598)
PhaeoP66_RS07205	COG4133	protoheme IX ABC transporter activity
PhaeoP66_RS07210	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PhaeoP66_RS07215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PhaeoP66_RS07225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PhaeoP66_RS07260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PhaeoP66_RS07275	COG0006	proline dipeptidase activity
PhaeoP66_RS07300	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PhaeoP66_RS07310	COG0840	transmembrane signaling receptor activity
PhaeoP66_RS07320	COG0544	peptidyl-prolyl cis-trans isomerase activity
PhaeoP66_RS07330	COG0737	Belongs to the 5'-nucleotidase family
PhaeoP66_RS07345	COG0359	binds to the 23S rRNA
PhaeoP66_RS07350	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PhaeoP66_RS07355	COG0360	Binds together with S18 to 16S ribosomal RNA
PhaeoP66_RS07370	COG2353	YceI-like domain
PhaeoP66_RS07385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PhaeoP66_RS07395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PhaeoP66_RS07400	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PhaeoP66_RS07410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PhaeoP66_RS07415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PhaeoP66_RS07430	COG4695	Portal protein
PhaeoP66_RS07525	COG0508	dehydrogenase complex catalyzes the overall conversion of
PhaeoP66_RS07530	COG0508	dehydrogenase complex catalyzes the overall conversion of
PhaeoP66_RS07530	COG0022	dehydrogenase e1 component
PhaeoP66_RS07535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PhaeoP66_RS07540	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PhaeoP66_RS07545	COG0126	phosphoglycerate kinase activity
PhaeoP66_RS07580	COG0739	heme binding
PhaeoP66_RS07585	COG2833	Protein of unknown function (DUF455)
PhaeoP66_RS07590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PhaeoP66_RS07600	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PhaeoP66_RS07615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PhaeoP66_RS07625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PhaeoP66_RS07655	COG3239	Fatty acid desaturase
PhaeoP66_RS07670	COG0517	IMP dehydrogenase activity
PhaeoP66_RS07670	COG0516	GMP reductase activity
PhaeoP66_RS07675	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PhaeoP66_RS07690	COG2354	Protein conserved in bacteria
PhaeoP66_RS07700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PhaeoP66_RS07725	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PhaeoP66_RS07740	COG1357	PFAM Pentapeptide repeats (8 copies)
PhaeoP66_RS07745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PhaeoP66_RS07755	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS07770	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PhaeoP66_RS07775	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PhaeoP66_RS07780	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PhaeoP66_RS07795	COG1138	Cytochrome C-type biogenesis protein
PhaeoP66_RS07800	COG3088	subunit of a heme lyase
PhaeoP66_RS07805	COG1024	Enoyl-CoA hydratase
PhaeoP66_RS07815	COG0372	Belongs to the citrate synthase family
PhaeoP66_RS07820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PhaeoP66_RS07825	COG2333	competence protein COMEC
PhaeoP66_RS07825	COG0658	competence protein
PhaeoP66_RS07830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PhaeoP66_RS07835	COG0303	'Molybdopterin
PhaeoP66_RS07840	COG0315	cyclic pyranopterin monophosphate synthase activity
PhaeoP66_RS07850	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PhaeoP66_RS07855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PhaeoP66_RS07870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PhaeoP66_RS07875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PhaeoP66_RS07880	COG0436	Aminotransferase
PhaeoP66_RS07890	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
PhaeoP66_RS07900	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PhaeoP66_RS07905	COG0259	pyridoxamine-phosphate oxidase activity
PhaeoP66_RS07910	COG1278	Cold shock
PhaeoP66_RS07925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PhaeoP66_RS07930	COG0738	Major facilitator superfamily
PhaeoP66_RS07935	COG0004	ammonium transporteR
PhaeoP66_RS07945	COG0626	cystathionine gamma-synthase activity
PhaeoP66_RS07960	COG0395	ABC-type sugar transport system, permease component
PhaeoP66_RS07965	COG3842	ATPase activity
PhaeoP66_RS07995	COG1522	sequence-specific DNA binding
PhaeoP66_RS08065	COG0215	cysteine-tRNA ligase activity
PhaeoP66_RS08070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PhaeoP66_RS08080	COG2814	Major facilitator Superfamily
PhaeoP66_RS08115	COG0010	Belongs to the arginase family
PhaeoP66_RS08130	COG1238	metal cluster binding
PhaeoP66_RS08140	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PhaeoP66_RS08145	COG4608	Belongs to the ABC transporter superfamily
PhaeoP66_RS08150	COG0444	Belongs to the ABC transporter superfamily
PhaeoP66_RS08155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PhaeoP66_RS08160	COG0601	transmembrane transport
PhaeoP66_RS08165	COG0747	negative chemotaxis
PhaeoP66_RS08180	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PhaeoP66_RS08200	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PhaeoP66_RS08225	COG0577	efflux transmembrane transporter activity
PhaeoP66_RS08230	COG1136	(ABC) transporter
PhaeoP66_RS08260	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PhaeoP66_RS08265	COG0248	Ppx GppA phosphatase
PhaeoP66_RS08275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PhaeoP66_RS08290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PhaeoP66_RS08380	COG3750	Belongs to the UPF0335 family
PhaeoP66_RS08430	COG4695	Portal protein
PhaeoP66_RS08495	COG3561	AntA/AntB antirepressor
PhaeoP66_RS08600	COG3108	Peptidase M15
PhaeoP66_RS08605	COG2989	Protein conserved in bacteria
PhaeoP66_RS08610	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PhaeoP66_RS08630	COG0433	COG0433 Predicted ATPase
PhaeoP66_RS08660	COG2133	pyrroloquinoline quinone binding
PhaeoP66_RS08670	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PhaeoP66_RS08680	COG1561	YicC-like family, N-terminal region
PhaeoP66_RS08685	COG0194	GDP metabolic process
PhaeoP66_RS08695	COG0626	cystathionine gamma-synthase activity
PhaeoP66_RS08700	COG5002	protein histidine kinase activity
PhaeoP66_RS08710	COG0573	inorganic phosphate transmembrane transporter activity
PhaeoP66_RS08720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PhaeoP66_RS08725	COG0704	Plays a role in the regulation of phosphate uptake
PhaeoP66_RS08730	COG0745	RESPONSE REGULATOR receiver
PhaeoP66_RS08735	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS08740	COG1960	acyl-CoA dehydrogenase activity
PhaeoP66_RS08745	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS08750	COG1946	Acyl-CoA thioesterase
PhaeoP66_RS08755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PhaeoP66_RS08760	COG1024	Enoyl-CoA hydratase
PhaeoP66_RS08785	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PhaeoP66_RS08790	COG2771	luxR family
PhaeoP66_RS08795	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PhaeoP66_RS08800	COG0052	Belongs to the universal ribosomal protein uS2 family
PhaeoP66_RS08825	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PhaeoP66_RS08830	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PhaeoP66_RS08835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PhaeoP66_RS08845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PhaeoP66_RS08850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PhaeoP66_RS08850	COG3743	rRNA binding
PhaeoP66_RS08870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PhaeoP66_RS08885	COG0719	Fe-S assembly protein
PhaeoP66_RS08890	COG0396	ATPase activity
PhaeoP66_RS08895	COG0393	Putative heavy-metal-binding
PhaeoP66_RS08905	COG0719	Fe-S assembly protein
PhaeoP66_RS08915	COG1959	2 iron, 2 sulfur cluster binding
PhaeoP66_RS08920	COG2945	thiolester hydrolase activity
PhaeoP66_RS08940	COG1217	gtp-binding protein TYPA
PhaeoP66_RS08955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PhaeoP66_RS08960	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PhaeoP66_RS08980	COG0516	GMP reductase activity
PhaeoP66_RS08980	COG0517	IMP dehydrogenase activity
PhaeoP66_RS08985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PhaeoP66_RS09010	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PhaeoP66_RS09015	COG5425	PFAM Usg family protein
PhaeoP66_RS09020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PhaeoP66_RS09035	COG1612	heme a metabolic process
PhaeoP66_RS09065	COG2313	pseudouridylate synthase activity
PhaeoP66_RS09080	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS09085	COG4166	transmembrane transport
PhaeoP66_RS09125	COG2814	Major facilitator Superfamily
PhaeoP66_RS09130	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PhaeoP66_RS09150	COG2084	Dehydrogenase
PhaeoP66_RS09155	COG2366	antibiotic biosynthetic process
PhaeoP66_RS09160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PhaeoP66_RS09165	COG1923	regulation of RNA biosynthetic process
PhaeoP66_RS09170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PhaeoP66_RS09175	COG0569	domain protein
PhaeoP66_RS09185	COG2204	response regulator
PhaeoP66_RS09190	COG5000	phosphorelay sensor kinase activity
PhaeoP66_RS09195	COG2204	response regulator
PhaeoP66_RS09200	COG3852	Histidine kinase
PhaeoP66_RS09205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PhaeoP66_RS09210	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PhaeoP66_RS09210	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PhaeoP66_RS09215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PhaeoP66_RS09220	COG1546	Belongs to the CinA family
PhaeoP66_RS09220	COG1058	Belongs to the CinA family
PhaeoP66_RS09225	COG0004	ammonium transporteR
PhaeoP66_RS09230	COG2867	negative regulation of translational initiation
PhaeoP66_RS09235	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PhaeoP66_RS09245	COG1473	amidohydrolase
PhaeoP66_RS09250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PhaeoP66_RS09270	COG5598	trimethylamine methyltransferase
PhaeoP66_RS09275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PhaeoP66_RS09275	COG0519	Catalyzes the synthesis of GMP from XMP
PhaeoP66_RS09300	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
PhaeoP66_RS09310	COG2326	polyphosphate kinase activity
PhaeoP66_RS09315	COG1309	transcriptional regulator
PhaeoP66_RS09325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PhaeoP66_RS09375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PhaeoP66_RS09385	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PhaeoP66_RS09390	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PhaeoP66_RS09405	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PhaeoP66_RS09410	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PhaeoP66_RS09420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PhaeoP66_RS09425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PhaeoP66_RS09435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PhaeoP66_RS09440	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PhaeoP66_RS09455	COG0482	sulfurtransferase activity
PhaeoP66_RS09460	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PhaeoP66_RS09465	COG3494	Protein of unknown function (DUF1009)
PhaeoP66_RS09470	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PhaeoP66_RS09475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PhaeoP66_RS09485	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PhaeoP66_RS09490	COG0750	zinc metalloprotease
PhaeoP66_RS09495	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PhaeoP66_RS09505	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PhaeoP66_RS09510	COG0233	cytoplasmic translational termination
PhaeoP66_RS09515	COG0528	UMP kinase activity
PhaeoP66_RS09520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PhaeoP66_RS09535	COG0601	transmembrane transport
PhaeoP66_RS09540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PhaeoP66_RS09545	COG4172	Belongs to the ABC transporter superfamily
PhaeoP66_RS09555	COG0741	lytic transglycosylase activity
PhaeoP66_RS09555	COG0739	heme binding
PhaeoP66_RS09555	COG1196	nuclear chromosome segregation
PhaeoP66_RS09560	COG0629	single-stranded DNA binding
PhaeoP66_RS09565	COG0840	transmembrane signaling receptor activity
PhaeoP66_RS09570	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PhaeoP66_RS09575	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PhaeoP66_RS09585	COG4974	Belongs to the 'phage' integrase family
PhaeoP66_RS09590	COG4536	flavin adenine dinucleotide binding
PhaeoP66_RS09610	COG1070	Carbohydrate kinase
PhaeoP66_RS09615	COG2115	Belongs to the xylose isomerase family
PhaeoP66_RS09630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PhaeoP66_RS09635	COG3264	Mechanosensitive ion channel
PhaeoP66_RS09635	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PhaeoP66_RS09645	COG0494	nUDIX hydrolase
PhaeoP66_RS09655	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PhaeoP66_RS09660	COG0415	Belongs to the DNA photolyase family
PhaeoP66_RS09665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PhaeoP66_RS09675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PhaeoP66_RS09680	COG0604	alcohol dehydrogenase
PhaeoP66_RS09685	COG2186	Transcriptional regulator
PhaeoP66_RS09700	COG1917	Cupin 2, conserved barrel domain protein
PhaeoP66_RS09700	COG2207	Transcriptional regulator
PhaeoP66_RS09710	COG2091	lysine biosynthetic process via aminoadipic acid
PhaeoP66_RS09715	COG1960	acyl-CoA dehydrogenase activity
PhaeoP66_RS09725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PhaeoP66_RS09730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PhaeoP66_RS09750	COG0318	PFAM AMP-dependent synthetase and ligase
PhaeoP66_RS09815	COG0577	efflux transmembrane transporter activity
PhaeoP66_RS09815	COG1136	(ABC) transporter
PhaeoP66_RS09835	COG2059	Chromate
PhaeoP66_RS09850	COG0114	fumarate hydratase activity
PhaeoP66_RS09870	COG2124	cytochrome p450
PhaeoP66_RS09880	COG0785	Cytochrome C biogenesis protein
PhaeoP66_RS09885	COG0425	Belongs to the sulfur carrier protein TusA family
PhaeoP66_RS09895	COG1530	ribonuclease E activity
PhaeoP66_RS09900	COG2204	response regulator
PhaeoP66_RS09910	COG0047	phosphoribosylformylglycinamidine synthase activity
PhaeoP66_RS09915	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PhaeoP66_RS09920	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PhaeoP66_RS09935	COG1410	methionine synthase
PhaeoP66_RS09935	COG0646	methionine synthase
PhaeoP66_RS09945	COG5012	cobalamin binding
PhaeoP66_RS09965	COG2166	iron-sulfur cluster assembly
PhaeoP66_RS09975	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PhaeoP66_RS09985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PhaeoP66_RS09990	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PhaeoP66_RS10000	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS10010	COG1609	Transcriptional regulator
PhaeoP66_RS10020	COG1175	transmembrane transport
PhaeoP66_RS10055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PhaeoP66_RS10075	COG4989	oxidoreductase activity
PhaeoP66_RS10085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PhaeoP66_RS10090	COG0673	inositol 2-dehydrogenase activity
PhaeoP66_RS10120	COG0745	RESPONSE REGULATOR receiver
PhaeoP66_RS10150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PhaeoP66_RS10155	COG0563	adenylate kinase activity
PhaeoP66_RS10175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PhaeoP66_RS10180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PhaeoP66_RS10185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PhaeoP66_RS10190	COG1116	anion transmembrane transporter activity
PhaeoP66_RS10205	COG1309	transcriptional regulator
PhaeoP66_RS10225	COG3750	Belongs to the UPF0335 family
PhaeoP66_RS10245	COG2391	methyltransferase activity
PhaeoP66_RS10275	COG0745	RESPONSE REGULATOR receiver
PhaeoP66_RS10305	COG0410	ABC transporter
PhaeoP66_RS10320	COG0439	Biotin carboxylase
PhaeoP66_RS10325	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PhaeoP66_RS10355	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PhaeoP66_RS10360	COG0740	serine-type endopeptidase activity
PhaeoP66_RS10390	COG0737	Belongs to the 5'-nucleotidase family
PhaeoP66_RS10395	COG3258	Cytochrome c
PhaeoP66_RS10420	COG0785	Cytochrome C biogenesis protein
PhaeoP66_RS10435	COG2391	methyltransferase activity
PhaeoP66_RS10450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PhaeoP66_RS10465	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PhaeoP66_RS10470	COG2943	transferase activity, transferring hexosyl groups
PhaeoP66_RS10485	COG2111	Na H antiporter
PhaeoP66_RS10485	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PhaeoP66_RS10490	COG1006	Multisubunit Na H antiporter MnhC subunit
PhaeoP66_RS10495	COG0651	ATP synthesis coupled electron transport
PhaeoP66_RS10505	COG2212	antiporter activity
PhaeoP66_RS10510	COG1320	monovalent cation:proton antiporter activity
PhaeoP66_RS10515	COG0709	Synthesizes selenophosphate from selenide and ATP
PhaeoP66_RS10520	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PhaeoP66_RS10535	COG0737	Belongs to the 5'-nucleotidase family
PhaeoP66_RS10555	COG0534	Mate efflux family protein
PhaeoP66_RS10575	COG0789	Transcriptional regulator
PhaeoP66_RS10580	COG1960	acyl-CoA dehydrogenase activity
PhaeoP66_RS10590	COG1960	acyl-CoA dehydrogenase activity
PhaeoP66_RS10600	COG0625	glutathione transferase activity
PhaeoP66_RS10605	COG0183	Belongs to the thiolase family
PhaeoP66_RS10610	COG1024	Enoyl-CoA hydratase
PhaeoP66_RS10610	COG1250	3-hydroxyacyl-CoA dehydrogenase
PhaeoP66_RS10625	COG0318	PFAM AMP-dependent synthetase and ligase
PhaeoP66_RS10640	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PhaeoP66_RS10645	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PhaeoP66_RS10650	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PhaeoP66_RS10655	COG0295	cytidine deaminase activity
PhaeoP66_RS10665	COG0281	malic enzyme
PhaeoP66_RS10665	COG0280	phosphate acetyltransferase
PhaeoP66_RS10680	COG0154	amidase activity
PhaeoP66_RS10685	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PhaeoP66_RS10690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PhaeoP66_RS10755	COG1522	sequence-specific DNA binding
PhaeoP66_RS10775	COG0483	inositol monophosphate 1-phosphatase activity
PhaeoP66_RS10780	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS10785	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PhaeoP66_RS10820	COG0525	valine-tRNA ligase activity
PhaeoP66_RS10855	COG4215	(ABC) transporter
PhaeoP66_RS10865	COG0174	glutamine synthetase
PhaeoP66_RS10870	COG0519	Catalyzes the synthesis of GMP from XMP
PhaeoP66_RS10870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PhaeoP66_RS10875	COG0174	glutamine synthetase
PhaeoP66_RS10880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PhaeoP66_RS10885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PhaeoP66_RS10890	COG1957	nucleoside hydrolase
PhaeoP66_RS10895	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PhaeoP66_RS10895	COG0456	acetyltransferase
PhaeoP66_RS10920	COG0148	phosphopyruvate hydratase activity
PhaeoP66_RS10925	COG0697	spore germination
PhaeoP66_RS10935	COG0513	Belongs to the DEAD box helicase family
PhaeoP66_RS10950	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PhaeoP66_RS10960	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PhaeoP66_RS10965	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PhaeoP66_RS10990	COG0488	(ABC) transporter
PhaeoP66_RS11010	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PhaeoP66_RS11015	COG0416	fatty acid biosynthetic process
PhaeoP66_RS11020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PhaeoP66_RS11025	COG0776	regulation of translation
PhaeoP66_RS11040	COG0717	Belongs to the dCTP deaminase family
PhaeoP66_RS11050	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PhaeoP66_RS11070	COG0018	arginyl-trna synthetase
PhaeoP66_RS11080	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PhaeoP66_RS11085	COG0316	Belongs to the HesB IscA family
PhaeoP66_RS11110	COG1278	Cold shock
PhaeoP66_RS11115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PhaeoP66_RS11125	COG0542	response to heat
PhaeoP66_RS11155	COG1162	GTPase activity
PhaeoP66_RS11185	COG0418	dihydroorotase activity
PhaeoP66_RS11190	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PhaeoP66_RS11195	COG0305	Participates in initiation and elongation during chromosome replication
PhaeoP66_RS11200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PhaeoP66_RS11205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PhaeoP66_RS11210	COG1127	ABC transporter
PhaeoP66_RS11240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PhaeoP66_RS11255	COG4221	oxidoreductase activity
PhaeoP66_RS11260	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PhaeoP66_RS11265	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PhaeoP66_RS11280	COG0698	ribose 5-phosphate isomerase
PhaeoP66_RS11285	COG0805	protein transport
PhaeoP66_RS11290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PhaeoP66_RS11295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PhaeoP66_RS11310	COG3842	ATPase activity
PhaeoP66_RS11315	COG4335	DNA alkylation repair
PhaeoP66_RS11320	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS11340	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PhaeoP66_RS11355	COG0513	Belongs to the DEAD box helicase family
PhaeoP66_RS11365	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PhaeoP66_RS11390	COG0713	ATP synthesis coupled electron transport
PhaeoP66_RS11405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PhaeoP66_RS11410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PhaeoP66_RS11450	COG0649	NAD binding
PhaeoP66_RS11455	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PhaeoP66_RS11460	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PhaeoP66_RS11470	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PhaeoP66_RS11485	COG4770	biotin carboxylase activity
PhaeoP66_RS11490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PhaeoP66_RS11500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PhaeoP66_RS11505	COG3047	cAMP biosynthetic process
PhaeoP66_RS11510	COG1960	acyl-CoA dehydrogenase activity
PhaeoP66_RS11530	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PhaeoP66_RS11550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PhaeoP66_RS11555	COG1519	Transferase
PhaeoP66_RS11565	COG1473	amidohydrolase
PhaeoP66_RS11570	COG1473	amidohydrolase
PhaeoP66_RS11575	COG1473	amidohydrolase
PhaeoP66_RS11580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PhaeoP66_RS11585	COG4172	Belongs to the ABC transporter superfamily
PhaeoP66_RS11595	COG0601	transmembrane transport
PhaeoP66_RS11600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PhaeoP66_RS11605	COG2391	methyltransferase activity
PhaeoP66_RS11630	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PhaeoP66_RS11650	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS11665	COG3483	tryptophan 2,3-dioxygenase activity
PhaeoP66_RS11670	COG1309	transcriptional regulator
PhaeoP66_RS11680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PhaeoP66_RS11680	COG2010	Cytochrome c
PhaeoP66_RS11685	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PhaeoP66_RS11695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PhaeoP66_RS11705	COG0308	aminopeptidase N
PhaeoP66_RS11720	COG2183	response to ionizing radiation
PhaeoP66_RS11725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PhaeoP66_RS11795	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PhaeoP66_RS11805	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PhaeoP66_RS11810	COG0849	cell division
PhaeoP66_RS11815	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PhaeoP66_RS11820	COG1181	Belongs to the D-alanine--D-alanine ligase family
PhaeoP66_RS11825	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PhaeoP66_RS11840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PhaeoP66_RS11845	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PhaeoP66_RS11855	COG2081	HI0933 family
PhaeoP66_RS11865	COG1846	Transcriptional regulator
PhaeoP66_RS11870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PhaeoP66_RS11875	COG2066	Belongs to the glutaminase family
PhaeoP66_RS11880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PhaeoP66_RS11890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PhaeoP66_RS11905	COG0275	rRNA processing
PhaeoP66_RS11910	COG2001	Belongs to the MraZ family
PhaeoP66_RS11915	COG0489	protein tyrosine kinase activity
PhaeoP66_RS11925	COG0210	DNA helicase
PhaeoP66_RS11940	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PhaeoP66_RS11975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PhaeoP66_RS11985	COG0131	Imidazoleglycerol-phosphate dehydratase
PhaeoP66_RS11990	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PhaeoP66_RS12015	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PhaeoP66_RS12030	COG0107	imidazoleglycerol-phosphate synthase activity
PhaeoP66_RS12035	COG0140	phosphoribosyl-ATP diphosphatase activity
PhaeoP66_RS12040	COG1832	CoA-binding protein
PhaeoP66_RS12050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PhaeoP66_RS12055	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PhaeoP66_RS12055	COG1618	nucleotide phosphatase activity, acting on free nucleotides
PhaeoP66_RS12060	COG4106	trans-aconitate 2-methyltransferase activity
PhaeoP66_RS12075	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PhaeoP66_RS12085	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PhaeoP66_RS12090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PhaeoP66_RS12115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PhaeoP66_RS12125	COG0840	transmembrane signaling receptor activity
PhaeoP66_RS12135	COG0564	pseudouridine synthase activity
PhaeoP66_RS12165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PhaeoP66_RS12170	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PhaeoP66_RS12205	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PhaeoP66_RS12205	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PhaeoP66_RS12210	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PhaeoP66_RS12215	COG0432	Pfam Uncharacterised protein family UPF0047
PhaeoP66_RS12230	COG4221	oxidoreductase activity
PhaeoP66_RS12240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PhaeoP66_RS12245	COG0358	DNA primase activity
PhaeoP66_RS12260	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PhaeoP66_RS12260	COG0446	pyridine nucleotide-disulphide oxidoreductase
PhaeoP66_RS12270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PhaeoP66_RS12275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PhaeoP66_RS12300	COG1741	Belongs to the pirin family
PhaeoP66_RS12325	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PhaeoP66_RS12350	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
PhaeoP66_RS12370	COG3706	GGDEF domain
PhaeoP66_RS12385	COG1595	DNA-templated transcription, initiation
PhaeoP66_RS12425	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS12430	COG0824	Thioesterase
PhaeoP66_RS12430	COG1250	3-hydroxyacyl-CoA dehydrogenase
PhaeoP66_RS12440	COG3246	L-lysine catabolic process to acetate
PhaeoP66_RS12450	COG0667	Aldo Keto reductase
PhaeoP66_RS12465	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PhaeoP66_RS12475	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS12575	COG2099	Precorrin-6x reductase
PhaeoP66_RS12590	COG2875	Belongs to the precorrin methyltransferase family
PhaeoP66_RS12595	COG1797	cobyrinic acid a,c-diamide synthase activity
PhaeoP66_RS12600	COG1648	precorrin-2 dehydrogenase activity
PhaeoP66_RS12600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PhaeoP66_RS12625	COG1686	Belongs to the peptidase S11 family
PhaeoP66_RS12630	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PhaeoP66_RS12640	COG0084	hydrolase, TatD family'
PhaeoP66_RS12645	COG1234	tRNA 3'-trailer cleavage
PhaeoP66_RS12685	COG3842	ATPase activity
PhaeoP66_RS12690	COG0366	Alpha amylase catalytic
PhaeoP66_RS12695	COG0395	ABC-type sugar transport system, permease component
PhaeoP66_RS12700	COG1175	transmembrane transport
PhaeoP66_RS12705	COG1653	transport
PhaeoP66_RS12710	COG1609	Transcriptional regulator
PhaeoP66_RS12715	COG2723	6-phospho-beta-galactosidase activity
PhaeoP66_RS12725	COG0006	proline dipeptidase activity
PhaeoP66_RS12730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PhaeoP66_RS12750	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PhaeoP66_RS12755	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PhaeoP66_RS12755	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PhaeoP66_RS12760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PhaeoP66_RS12765	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS12770	COG1063	alcohol dehydrogenase
PhaeoP66_RS12795	COG3916	Acyl-homoserine-lactone synthase
PhaeoP66_RS12850	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PhaeoP66_RS12855	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PhaeoP66_RS12865	COG1329	Transcriptional regulator
PhaeoP66_RS12870	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PhaeoP66_RS12875	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PhaeoP66_RS12905	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PhaeoP66_RS12935	COG1175	transmembrane transport
PhaeoP66_RS12940	COG0395	ABC-type sugar transport system, permease component
PhaeoP66_RS12950	COG0129	dihydroxy-acid dehydratase activity
PhaeoP66_RS12955	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS12965	COG0800	Aldolase
PhaeoP66_RS12985	COG4214	carbohydrate transport
PhaeoP66_RS13000	COG0673	inositol 2-dehydrogenase activity
PhaeoP66_RS13010	COG0673	inositol 2-dehydrogenase activity
PhaeoP66_RS13015	COG3962	Belongs to the TPP enzyme family
PhaeoP66_RS13020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PhaeoP66_RS13035	COG0673	inositol 2-dehydrogenase activity
PhaeoP66_RS13045	COG1609	Transcriptional regulator
PhaeoP66_RS13060	COG3391	amine dehydrogenase activity
PhaeoP66_RS13070	COG1858	cytochrome C peroxidase
PhaeoP66_RS13085	COG1115	amino acid carrier protein
PhaeoP66_RS13095	COG1970	mechanosensitive ion channel activity
PhaeoP66_RS13100	COG0668	transmembrane transport
PhaeoP66_RS13125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PhaeoP66_RS13125	COG0072	phenylalanine-tRNA ligase activity
PhaeoP66_RS13135	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PhaeoP66_RS13140	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PhaeoP66_RS13145	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PhaeoP66_RS13155	COG0469	pyruvate kinase activity
PhaeoP66_RS13180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PhaeoP66_RS13185	COG4608	Belongs to the ABC transporter superfamily
PhaeoP66_RS13190	COG0444	Belongs to the ABC transporter superfamily
PhaeoP66_RS13195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PhaeoP66_RS13200	COG0601	transmembrane transport
PhaeoP66_RS13225	COG0321	lipoyl(octanoyl) transferase activity
PhaeoP66_RS13235	COG0537	adenosine 5'-monophosphoramidase activity
PhaeoP66_RS13260	COG0505	Belongs to the CarA family
PhaeoP66_RS13270	COG1802	Transcriptional regulator
PhaeoP66_RS13295	COG1522	sequence-specific DNA binding
PhaeoP66_RS13305	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PhaeoP66_RS13320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PhaeoP66_RS13325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PhaeoP66_RS13330	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PhaeoP66_RS13340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PhaeoP66_RS13340	COG0574	Belongs to the PEP-utilizing enzyme family
PhaeoP66_RS13345	COG0751	glycine-tRNA ligase activity
PhaeoP66_RS13350	COG0786	glutamate:sodium symporter activity
PhaeoP66_RS13360	COG0752	glycyl-tRNA synthetase alpha subunit
PhaeoP66_RS13390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PhaeoP66_RS13400	COG0659	secondary active sulfate transmembrane transporter activity
PhaeoP66_RS13405	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PhaeoP66_RS13410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PhaeoP66_RS13415	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PhaeoP66_RS13420	COG2271	Major facilitator Superfamily
PhaeoP66_RS13435	COG0612	Peptidase, M16
PhaeoP66_RS13455	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PhaeoP66_RS13465	COG0109	protoheme IX farnesyltransferase activity
PhaeoP66_RS13475	COG0312	modulator of DNA gyrase
PhaeoP66_RS13480	COG0758	DNA mediated transformation
PhaeoP66_RS13485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PhaeoP66_RS13505	COG0741	lytic transglycosylase activity
PhaeoP66_RS13520	COG4964	Belongs to the GSP D family
PhaeoP66_RS13525	COG2885	chlorophyll binding
PhaeoP66_RS13570	COG1201	RNA secondary structure unwinding
PhaeoP66_RS13585	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PhaeoP66_RS13590	COG0287	Prephenate dehydrogenase
PhaeoP66_RS13590	COG1605	Chorismate mutase
PhaeoP66_RS13595	COG2759	Belongs to the formate--tetrahydrofolate ligase family
PhaeoP66_RS13605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PhaeoP66_RS13610	COG0037	tRNA processing
PhaeoP66_RS13620	COG2885	chlorophyll binding
PhaeoP66_RS13625	COG0823	Involved in the tonB-independent uptake of proteins
PhaeoP66_RS13645	COG0824	Thioesterase
PhaeoP66_RS13655	COG2255	four-way junction helicase activity
PhaeoP66_RS13660	COG0632	four-way junction helicase activity
PhaeoP66_RS13665	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PhaeoP66_RS13680	COG2264	protein methyltransferase activity
PhaeoP66_RS13690	COG2391	methyltransferase activity
PhaeoP66_RS13700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PhaeoP66_RS13710	COG4974	Belongs to the 'phage' integrase family
PhaeoP66_RS13720	COG1183	phosphatidylcholine synthase activity
PhaeoP66_RS13725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PhaeoP66_RS13735	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PhaeoP66_RS13750	COG3768	UPF0283 membrane protein
PhaeoP66_RS13760	COG3106	COG3106 Predicted ATPase
PhaeoP66_RS13765	COG0101	tRNA pseudouridine synthase activity
PhaeoP66_RS13775	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PhaeoP66_RS13780	COG0602	queuosine metabolic process
PhaeoP66_RS13785	COG0720	synthase
PhaeoP66_RS13790	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PhaeoP66_RS13800	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PhaeoP66_RS13800	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PhaeoP66_RS13805	COG0509	glycine decarboxylation via glycine cleavage system
PhaeoP66_RS13825	COG3257	ureidoglycine aminohydrolase activity
PhaeoP66_RS13845	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
PhaeoP66_RS13855	COG2351	hydroxyisourate hydrolase activity
PhaeoP66_RS13880	COG0837	glucose binding
PhaeoP66_RS13895	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PhaeoP66_RS13940	COG0438	transferase activity, transferring glycosyl groups
PhaeoP66_RS13940	COG0297	glycogen (starch) synthase activity
PhaeoP66_RS13970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PhaeoP66_RS13970	COG0116	Belongs to the methyltransferase superfamily
PhaeoP66_RS13980	COG3842	ATPase activity
PhaeoP66_RS13985	COG3842	ATPase activity
PhaeoP66_RS13990	COG1175	transmembrane transport
PhaeoP66_RS13995	COG0395	ABC-type sugar transport system, permease component
PhaeoP66_RS14015	COG0840	transmembrane signaling receptor activity
PhaeoP66_RS14020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PhaeoP66_RS14025	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS14065	COG0582	viral genome integration into host DNA
PhaeoP66_RS14180	COG4638	Rieske (2fe-2S)
PhaeoP66_RS14200	COG0012	GTP binding
PhaeoP66_RS14210	COG0159	tryptophan synthase activity
PhaeoP66_RS14220	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PhaeoP66_RS14225	COG0193	aminoacyl-tRNA hydrolase activity
PhaeoP66_RS14240	COG0133	tryptophan synthase activity
PhaeoP66_RS14245	COG0135	phosphoribosylanthranilate isomerase activity
PhaeoP66_RS14255	COG0776	regulation of translation
PhaeoP66_RS14260	COG0539	negative regulation of cytoplasmic translation
PhaeoP66_RS14265	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PhaeoP66_RS14270	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PhaeoP66_RS14275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PhaeoP66_RS14285	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PhaeoP66_RS14290	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PhaeoP66_RS14295	COG1253	flavin adenine dinucleotide binding
PhaeoP66_RS14300	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PhaeoP66_RS14305	COG1702	phosphate starvation-inducible protein PhoH
PhaeoP66_RS14315	COG2885	chlorophyll binding
PhaeoP66_RS14320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PhaeoP66_RS14335	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS14345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PhaeoP66_RS14350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PhaeoP66_RS14355	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PhaeoP66_RS14360	COG2070	2-Nitropropane dioxygenase
PhaeoP66_RS14365	COG1047	Peptidyl-prolyl cis-trans
PhaeoP66_RS14390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PhaeoP66_RS14405	COG4948	Mandelate Racemase Muconate Lactonizing
PhaeoP66_RS14415	COG1132	(ABC) transporter
PhaeoP66_RS14425	COG1522	sequence-specific DNA binding
PhaeoP66_RS14460	COG0601	transmembrane transport
PhaeoP66_RS14465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PhaeoP66_RS14470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PhaeoP66_RS14475	COG0668	transmembrane transport
PhaeoP66_RS14490	COG0438	transferase activity, transferring glycosyl groups
PhaeoP66_RS14495	COG0588	phosphoglycerate mutase activity
PhaeoP66_RS14515	COG3454	Phosphonate metabolism
PhaeoP66_RS14530	COG4778	phosphonate C-P lyase system protein PhnL
PhaeoP66_RS14535	COG4107	phosphonate C-P lyase system protein PhnK
PhaeoP66_RS14540	COG3627	carbon phosphorus lyase activity
PhaeoP66_RS14545	COG3626	phosphonate metabolism
PhaeoP66_RS14555	COG3624	Phosphonate C-P lyase system protein PhnG
PhaeoP66_RS14560	COG2188	Transcriptional regulator
PhaeoP66_RS14565	COG0110	maltose O-acetyltransferase activity
PhaeoP66_RS14570	COG3639	organic phosphonate transmembrane transporter activity
PhaeoP66_RS14575	COG3639	organic phosphonate transmembrane transporter activity
PhaeoP66_RS14580	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PhaeoP66_RS14585	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PhaeoP66_RS14595	COG0318	PFAM AMP-dependent synthetase and ligase
PhaeoP66_RS14605	COG1960	acyl-CoA dehydrogenase activity
PhaeoP66_RS14610	COG1960	acyl-CoA dehydrogenase activity
PhaeoP66_RS14615	COG0183	Belongs to the thiolase family
PhaeoP66_RS14620	COG1024	Enoyl-CoA hydratase
PhaeoP66_RS14620	COG1250	3-hydroxyacyl-CoA dehydrogenase
PhaeoP66_RS14635	COG3396	Phenylacetate-CoA oxygenase
PhaeoP66_RS14640	COG3460	Phenylacetate-CoA oxygenase
PhaeoP66_RS14645	COG3396	Phenylacetate-CoA oxygenase
PhaeoP66_RS14650	COG2151	metal-sulfur cluster biosynthetic enzyme
PhaeoP66_RS14655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PhaeoP66_RS14675	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PhaeoP66_RS14680	COG1214	PFAM Peptidase M22, glycoprotease
PhaeoP66_RS14690	COG1744	ABC transporter substrate-binding protein PnrA-like
PhaeoP66_RS14695	COG3845	ABC transporter
PhaeoP66_RS14700	COG4603	Belongs to the binding-protein-dependent transport system permease family
PhaeoP66_RS14705	COG1079	Belongs to the binding-protein-dependent transport system permease family
PhaeoP66_RS14710	COG0730	response to heat
PhaeoP66_RS14720	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS14740	COG0604	alcohol dehydrogenase
PhaeoP66_RS14745	COG2937	Belongs to the GPAT DAPAT family
PhaeoP66_RS14755	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PhaeoP66_RS14755	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PhaeoP66_RS14765	COG0813	purine-nucleoside phosphorylase activity
PhaeoP66_RS14775	COG0019	diaminopimelate decarboxylase activity
PhaeoP66_RS14825	COG2030	dehydratase
PhaeoP66_RS14855	COG0039	L-malate dehydrogenase activity
PhaeoP66_RS14865	COG0045	succinate-CoA ligase (ADP-forming) activity
PhaeoP66_RS14885	COG0508	dehydrogenase complex catalyzes the overall conversion of
PhaeoP66_RS14920	COG2884	Cell division ATP-binding protein ftsE
PhaeoP66_RS14935	COG0019	diaminopimelate decarboxylase activity
PhaeoP66_RS14945	COG0165	Argininosuccinate lyase
PhaeoP66_RS14950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PhaeoP66_RS14980	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS15005	COG0142	geranyltranstransferase activity
PhaeoP66_RS15010	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PhaeoP66_RS15025	COG0789	Transcriptional regulator
PhaeoP66_RS15040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PhaeoP66_RS15050	COG0303	'Molybdopterin
PhaeoP66_RS15055	COG1763	Mo-molybdopterin cofactor biosynthetic process
PhaeoP66_RS15060	COG0746	molybdenum cofactor guanylyltransferase activity
PhaeoP66_RS15065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PhaeoP66_RS15105	COG1960	acyl-CoA dehydrogenase activity
PhaeoP66_RS15110	COG0009	L-threonylcarbamoyladenylate synthase
PhaeoP66_RS15115	COG1678	Uncharacterized ACR, COG1678
PhaeoP66_RS15125	COG0494	nUDIX hydrolase
PhaeoP66_RS15130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PhaeoP66_RS15140	COG0521	Mo-molybdopterin cofactor biosynthetic process
PhaeoP66_RS15145	COG1573	uracil-dna glycosylase
PhaeoP66_RS15150	COG0540	Belongs to the ATCase OTCase family
PhaeoP66_RS15170	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PhaeoP66_RS15200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PhaeoP66_RS15210	COG2885	chlorophyll binding
PhaeoP66_RS15220	COG0314	molybdopterin synthase activity
PhaeoP66_RS15230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PhaeoP66_RS15235	COG0322	excinuclease ABC activity
PhaeoP66_RS15240	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS15260	COG0842	Transport permease protein
PhaeoP66_RS15265	COG1131	(ABC) transporter
PhaeoP66_RS15285	COG0793	Belongs to the peptidase S41A family
PhaeoP66_RS15295	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PhaeoP66_RS15300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PhaeoP66_RS15300	COG2169	Transcriptional regulator
PhaeoP66_RS15310	COG3842	ATPase activity
PhaeoP66_RS15315	COG0395	ABC-type sugar transport system, permease component
PhaeoP66_RS15325	COG1653	transport
PhaeoP66_RS15330	COG1609	Transcriptional regulator
PhaeoP66_RS15345	COG0604	alcohol dehydrogenase
PhaeoP66_RS15365	COG1022	Amp-dependent synthetase and ligase
PhaeoP66_RS15380	COG4214	carbohydrate transport
PhaeoP66_RS15390	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS15395	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PhaeoP66_RS15400	COG3485	protocatechuate 3,4-dioxygenase
PhaeoP66_RS15405	COG3485	protocatechuate 3,4-dioxygenase
PhaeoP66_RS15420	COG2217	Heavy metal translocating P-type atpase
PhaeoP66_RS15425	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PhaeoP66_RS15430	COG1802	Transcriptional regulator
PhaeoP66_RS15435	COG2719	SpoVR family
PhaeoP66_RS15440	COG2718	Belongs to the UPF0229 family
PhaeoP66_RS15445	COG2766	serine protein kinase
PhaeoP66_RS15460	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
PhaeoP66_RS15465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PhaeoP66_RS15470	COG3591	Belongs to the peptidase S1B family
PhaeoP66_RS15475	COG2814	Major facilitator Superfamily
PhaeoP66_RS15480	COG0789	Transcriptional regulator
PhaeoP66_RS15505	COG2116	formate transmembrane transporter activity
PhaeoP66_RS15530	COG0463	Glycosyl transferase, family 2
PhaeoP66_RS15565	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS15575	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS15580	COG2814	Major facilitator Superfamily
PhaeoP66_RS15585	COG1902	pentaerythritol trinitrate reductase activity
PhaeoP66_RS15635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PhaeoP66_RS15670	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PhaeoP66_RS15675	COG1530	ribonuclease E activity
PhaeoP66_RS15685	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PhaeoP66_RS15690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PhaeoP66_RS15715	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PhaeoP66_RS15730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PhaeoP66_RS15965	COG3750	Belongs to the UPF0335 family
PhaeoP66_RS16005	COG2189	Belongs to the N(4) N(6)-methyltransferase family
PhaeoP66_RS16075	COG3842	ATPase activity
PhaeoP66_RS16090	COG1283	sodium-dependent phosphate transmembrane transporter activity
PhaeoP66_RS16095	COG1349	DNA-binding transcription factor activity
PhaeoP66_RS16105	COG2379	hydroxypyruvate reductase
PhaeoP66_RS16130	COG0411	ABC transporter
PhaeoP66_RS16160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PhaeoP66_RS16175	COG0288	reversible hydration of carbon dioxide
PhaeoP66_RS16185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PhaeoP66_RS16190	COG0791	NLP P60 protein
PhaeoP66_RS16210	COG1309	transcriptional regulator
PhaeoP66_RS16220	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PhaeoP66_RS16230	COG1671	Belongs to the UPF0178 family
PhaeoP66_RS16245	COG2423	ornithine cyclodeaminase activity
PhaeoP66_RS16250	COG2271	Major facilitator Superfamily
PhaeoP66_RS16255	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PhaeoP66_RS16265	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PhaeoP66_RS16295	COG1131	(ABC) transporter
PhaeoP66_RS16305	COG5001	Diguanylate cyclase
PhaeoP66_RS16305	COG3300	MHYT domain
PhaeoP66_RS16310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PhaeoP66_RS16310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PhaeoP66_RS16320	COG3622	Belongs to the hyi family
PhaeoP66_RS16330	COG0714	Associated with various cellular activities
PhaeoP66_RS16350	COG4953	penicillin-binding protein 1C
PhaeoP66_RS16355	COG2373	Large extracellular alpha-helical protein
PhaeoP66_RS16360	COG5002	protein histidine kinase activity
PhaeoP66_RS16360	COG2205	protein histidine kinase activity
PhaeoP66_RS16360	COG0784	Response regulator, receiver
PhaeoP66_RS16365	COG3022	response to hydroperoxide
PhaeoP66_RS16370	COG0514	ATP-dependent DNA helicase (RecQ)
PhaeoP66_RS16385	COG2270	Major facilitator Superfamily
PhaeoP66_RS16390	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
PhaeoP66_RS16415	COG3191	aminopeptidase activity
PhaeoP66_RS16420	COG3474	cytochrome
PhaeoP66_RS16425	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
PhaeoP66_RS16435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PhaeoP66_RS16440	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PhaeoP66_RS16445	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PhaeoP66_RS16465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PhaeoP66_RS16485	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PhaeoP66_RS16490	COG2205	protein histidine kinase activity
PhaeoP66_RS16490	COG0784	Response regulator, receiver
PhaeoP66_RS16490	COG2198	Histidine kinase
PhaeoP66_RS16495	COG1335	isochorismatase
PhaeoP66_RS16500	COG1054	Belongs to the UPF0176 family
PhaeoP66_RS16515	COG3971	2-oxopent-4-enoate hydratase activity
PhaeoP66_RS16520	COG0179	Fumarylacetoacetate (FAA) hydrolase
PhaeoP66_RS16530	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS16540	COG5441	Belongs to the UPF0261 family
PhaeoP66_RS16545	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS16570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PhaeoP66_RS16610	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PhaeoP66_RS16615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PhaeoP66_RS16620	COG0069	glutamate synthase activity
PhaeoP66_RS16635	COG0542	response to heat
PhaeoP66_RS16640	COG0284	orotidine-5'-phosphate decarboxylase activity
PhaeoP66_RS16650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PhaeoP66_RS16665	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PhaeoP66_RS16670	COG1840	ABC-type Fe3 transport system, periplasmic component
PhaeoP66_RS16680	COG0523	cobalamin synthesis protein
PhaeoP66_RS16685	COG1178	ABC-type Fe3 transport system permease component
PhaeoP66_RS16690	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
PhaeoP66_RS16735	COG4191	Histidine kinase
PhaeoP66_RS16755	COG0625	glutathione transferase activity
PhaeoP66_RS16790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PhaeoP66_RS16795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PhaeoP66_RS16795	COG1321	iron dependent repressor
PhaeoP66_RS16800	COG1121	(ABC) transporter
PhaeoP66_RS16805	COG0803	Belongs to the bacterial solute-binding protein 9 family
PhaeoP66_RS16815	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS16820	COG0612	Peptidase, M16
PhaeoP66_RS16825	COG0612	Peptidase, M16
PhaeoP66_RS16845	COG0138	bifunctional purine biosynthesis protein purh
PhaeoP66_RS16855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PhaeoP66_RS16870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PhaeoP66_RS16875	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PhaeoP66_RS16885	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PhaeoP66_RS16900	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PhaeoP66_RS16910	COG1185	polyribonucleotide nucleotidyltransferase activity
PhaeoP66_RS16920	COG0450	alkyl hydroperoxide reductase
PhaeoP66_RS16945	COG0564	pseudouridine synthase activity
PhaeoP66_RS16985	COG1280	lysine exporter protein (LysE YggA)
PhaeoP66_RS17000	COG0183	Belongs to the thiolase family
PhaeoP66_RS17010	COG2172	sigma factor antagonist activity
PhaeoP66_RS17015	COG0405	Gamma-glutamyltransferase
PhaeoP66_RS17025	COG3118	belongs to the thioredoxin family
PhaeoP66_RS17035	COG2835	tetraacyldisaccharide 4'-kinase activity
PhaeoP66_RS17040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PhaeoP66_RS17045	COG0154	amidase activity
PhaeoP66_RS17050	COG0436	Aminotransferase
PhaeoP66_RS17055	COG1674	ftsk spoiiie
PhaeoP66_RS17075	COG0745	RESPONSE REGULATOR receiver
PhaeoP66_RS17105	COG0495	leucyl-tRNA aminoacylation
PhaeoP66_RS17120	COG0625	glutathione transferase activity
PhaeoP66_RS17125	COG2081	HI0933 family
PhaeoP66_RS17135	COG1024	Enoyl-CoA hydratase
PhaeoP66_RS17150	COG0312	modulator of DNA gyrase
PhaeoP66_RS17165	COG1663	tetraacyldisaccharide 4'-kinase activity
PhaeoP66_RS17180	COG1194	a g-specific adenine glycosylase
PhaeoP66_RS17185	COG3239	Fatty acid desaturase
PhaeoP66_RS17200	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PhaeoP66_RS17230	COG0022	dehydrogenase e1 component
PhaeoP66_RS17235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PhaeoP66_RS17250	COG1172	Belongs to the binding-protein-dependent transport system permease family
PhaeoP66_RS17255	COG0559	Belongs to the binding-protein-dependent transport system permease family
PhaeoP66_RS17265	COG0829	nickel cation binding
PhaeoP66_RS17270	COG0831	urea catabolic process
PhaeoP66_RS17280	COG0832	Belongs to the urease beta subunit family
PhaeoP66_RS17285	COG0804	urea catabolic process
PhaeoP66_RS17290	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PhaeoP66_RS17295	COG0830	nickel cation binding
PhaeoP66_RS17300	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PhaeoP66_RS17310	COG2994	toxin metabolic process
PhaeoP66_RS17330	COG3620	sequence-specific DNA binding
PhaeoP66_RS17390	COG1609	Transcriptional regulator
PhaeoP66_RS17395	COG3214	Protein conserved in bacteria
PhaeoP66_RS17415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PhaeoP66_RS17430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PhaeoP66_RS17435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PhaeoP66_RS17460	COG0625	glutathione transferase activity
PhaeoP66_RS17470	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
PhaeoP66_RS17475	COG1178	ABC-type Fe3 transport system permease component
PhaeoP66_RS17480	COG4143	(ABC) transporter
PhaeoP66_RS17485	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PhaeoP66_RS17490	COG0318	PFAM AMP-dependent synthetase and ligase
PhaeoP66_RS17495	COG0697	spore germination
PhaeoP66_RS17500	COG1846	Transcriptional regulator
PhaeoP66_RS17505	COG1764	response to oxidative stress
PhaeoP66_RS17510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PhaeoP66_RS17515	COG1846	Transcriptional regulator
PhaeoP66_RS17520	COG0745	RESPONSE REGULATOR receiver
PhaeoP66_RS17530	COG1722	exodeoxyribonuclease VII activity
PhaeoP66_RS17535	COG0142	geranyltranstransferase activity
PhaeoP66_RS17540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PhaeoP66_RS17565	COG1960	acyl-CoA dehydrogenase activity
PhaeoP66_RS17575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PhaeoP66_RS17580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PhaeoP66_RS17585	COG0776	regulation of translation
PhaeoP66_RS17595	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PhaeoP66_RS17600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PhaeoP66_RS17610	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PhaeoP66_RS17615	COG1063	alcohol dehydrogenase
PhaeoP66_RS17620	COG0156	8-amino-7-oxononanoate synthase activity
PhaeoP66_RS17625	COG1396	sequence-specific DNA binding
PhaeoP66_RS17630	COG0183	Belongs to the thiolase family
PhaeoP66_RS17640	COG1176	ABC-type spermidine putrescine transport system, permease component I
PhaeoP66_RS17650	COG3842	ATPase activity
PhaeoP66_RS17660	COG1802	Transcriptional regulator
PhaeoP66_RS17670	COG3842	ATPase activity
PhaeoP66_RS17675	COG1176	ABC-type spermidine putrescine transport system, permease component I
PhaeoP66_RS17680	COG1177	transmembrane transport
PhaeoP66_RS17690	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PhaeoP66_RS17700	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PhaeoP66_RS17720	COG0443	Heat shock 70 kDa protein
PhaeoP66_RS17725	COG0484	heat shock protein binding
PhaeoP66_RS17730	COG2003	Belongs to the UPF0758 family
PhaeoP66_RS17745	COG0653	protein targeting
PhaeoP66_RS17750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PhaeoP66_RS17755	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PhaeoP66_RS17760	COG0494	nUDIX hydrolase
PhaeoP66_RS17765	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PhaeoP66_RS17780	COG0779	Required for maturation of 30S ribosomal subunits
PhaeoP66_RS17795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PhaeoP66_RS17805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PhaeoP66_RS17815	COG1040	competence protein
PhaeoP66_RS17830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PhaeoP66_RS17850	COG3034	peptidoglycan biosynthetic process
PhaeoP66_RS17860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PhaeoP66_RS17865	COG1132	(ABC) transporter
PhaeoP66_RS17870	COG1132	(ABC) transporter
PhaeoP66_RS17875	COG0617	tRNA 3'-terminal CCA addition
PhaeoP66_RS17880	COG0494	nUDIX hydrolase
PhaeoP66_RS17895	COG0745	RESPONSE REGULATOR receiver
PhaeoP66_RS17905	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PhaeoP66_RS17915	COG0137	argininosuccinate synthase activity
PhaeoP66_RS17940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PhaeoP66_RS17950	COG0281	malic enzyme
PhaeoP66_RS17950	COG0280	phosphate acetyltransferase
PhaeoP66_RS17955	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PhaeoP66_RS17960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PhaeoP66_RS17970	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PhaeoP66_RS17975	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PhaeoP66_RS17980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PhaeoP66_RS18000	COG0357	Ribosomal RNA small subunit methyltransferase G
PhaeoP66_RS18005	COG0445	tRNA wobble uridine modification
PhaeoP66_RS18010	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PhaeoP66_RS18015	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PhaeoP66_RS18020	COG1981	membrane
PhaeoP66_RS18025	COG0424	maF-like protein
PhaeoP66_RS18030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PhaeoP66_RS18035	COG0237	dephospho-CoA kinase activity
PhaeoP66_RS18040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PhaeoP66_RS18045	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PhaeoP66_RS18075	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PhaeoP66_RS18085	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PhaeoP66_RS18110	COG1074	ATP-dependent DNA helicase activity
PhaeoP66_RS18120	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PhaeoP66_RS18125	COG3178	'Phosphotransferase
PhaeoP66_RS18130	COG0802	atpase or kinase
PhaeoP66_RS18145	COG1999	signal sequence binding
PhaeoP66_RS18150	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PhaeoP66_RS18155	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
PhaeoP66_RS18165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PhaeoP66_RS18195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PhaeoP66_RS18200	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PhaeoP66_RS18255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PhaeoP66_RS18285	COG3668	Plasmid stabilization system
PhaeoP66_RS18290	COG3609	addiction module antidote protein, CC2985 family
PhaeoP66_RS18330	COG0318	PFAM AMP-dependent synthetase and ligase
PhaeoP66_RS18355	COG1706	bacterial-type flagellum-dependent cell motility
PhaeoP66_RS18360	COG1338	Plays a role in the flagellum-specific transport system
PhaeoP66_RS18365	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PhaeoP66_RS18375	COG1766	The M ring may be actively involved in energy transduction
PhaeoP66_RS18395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PhaeoP66_RS18410	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PhaeoP66_RS18420	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PhaeoP66_RS18435	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PhaeoP66_RS18445	COG4786	Flagellar basal body rod
PhaeoP66_RS18450	COG4786	Flagellar basal body rod
PhaeoP66_RS18455	COG1987	bacterial-type flagellum assembly
PhaeoP66_RS18460	COG1677	Flagellar hook-basal body complex protein FliE
PhaeoP66_RS18465	COG1558	bacterial-type flagellum-dependent cell motility
PhaeoP66_RS18470	COG1815	bacterial-type flagellum-dependent cell motility
PhaeoP66_RS18480	COG5443	negative regulation of bacterial-type flagellum assembly
PhaeoP66_RS18490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PhaeoP66_RS18510	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PhaeoP66_RS18535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PhaeoP66_RS18540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PhaeoP66_RS18545	COG1137	ATPase activity
PhaeoP66_RS18560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PhaeoP66_RS18560	COG0517	IMP dehydrogenase activity
PhaeoP66_RS18565	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PhaeoP66_RS18590	COG1968	undecaprenyl-diphosphatase activity
PhaeoP66_RS18605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PhaeoP66_RS18615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PhaeoP66_RS18620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PhaeoP66_RS18625	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PhaeoP66_RS18630	COG0560	Phosphoserine phosphatase
PhaeoP66_RS18630	COG3830	Belongs to the UPF0237 family
PhaeoP66_RS18670	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PhaeoP66_RS18695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PhaeoP66_RS18705	COG2171	N-acyltransferase activity
PhaeoP66_RS18710	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PhaeoP66_RS18720	COG2986	histidine ammonia-lyase
PhaeoP66_RS18725	COG1228	amidohydrolase
PhaeoP66_RS18745	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PhaeoP66_RS18760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PhaeoP66_RS18765	COG0557	exoribonuclease II activity
PhaeoP66_RS18780	COG2951	lytic endotransglycosylase activity
PhaeoP66_RS18790	COG2226	methyltransferase
PhaeoP66_RS18795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PhaeoP66_RS18800	COG1024	Enoyl-CoA hydratase
PhaeoP66_RS18805	COG0268	Binds directly to 16S ribosomal RNA
PhaeoP66_RS18820	COG1192	Involved in chromosome partitioning
PhaeoP66_RS18840	COG1215	transferase activity, transferring glycosyl groups
PhaeoP66_RS18845	COG1215	transferase activity, transferring glycosyl groups
PhaeoP66_RS18865	COG1215	transferase activity, transferring glycosyl groups
PhaeoP66_RS18870	COG1215	transferase activity, transferring glycosyl groups
PhaeoP66_RS18875	COG0438	transferase activity, transferring glycosyl groups
PhaeoP66_RS18890	COG0840	transmembrane signaling receptor activity
PhaeoP66_RS18905	COG1522	sequence-specific DNA binding
PhaeoP66_RS18925	COG4948	Mandelate Racemase Muconate Lactonizing
PhaeoP66_RS18930	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS18940	COG0783	Belongs to the Dps family
PhaeoP66_RS18950	COG1802	Transcriptional regulator
PhaeoP66_RS18955	COG3938	Belongs to the proline racemase family
PhaeoP66_RS18965	COG0747	negative chemotaxis
PhaeoP66_RS18970	COG0601	transmembrane transport
PhaeoP66_RS18975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PhaeoP66_RS18985	COG4608	Belongs to the ABC transporter superfamily
PhaeoP66_RS18995	COG0840	transmembrane signaling receptor activity
PhaeoP66_RS19000	COG2244	polysaccharide biosynthetic process
PhaeoP66_RS19010	COG2017	converts alpha-aldose to the beta-anomer
PhaeoP66_RS19015	COG1858	cytochrome C peroxidase
PhaeoP66_RS19030	COG4213	ABC transporter substrate-binding protein
PhaeoP66_RS19035	COG4214	carbohydrate transport
PhaeoP66_RS19040	COG1129	ABC transporter
PhaeoP66_RS19045	COG0789	Transcriptional regulator
PhaeoP66_RS19065	COG1793	dna ligase
PhaeoP66_RS19075	COG0534	Mate efflux family protein
PhaeoP66_RS19085	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS19115	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PhaeoP66_RS19120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PhaeoP66_RS19140	COG2951	lytic endotransglycosylase activity
PhaeoP66_RS19145	COG0740	serine-type endopeptidase activity
PhaeoP66_RS19155	COG1285	pathogenesis
PhaeoP66_RS19160	COG1366	Belongs to the anti-sigma-factor antagonist family
PhaeoP66_RS19165	COG1366	Belongs to the anti-sigma-factor antagonist family
PhaeoP66_RS19175	COG2172	sigma factor antagonist activity
PhaeoP66_RS19185	COG1473	amidohydrolase
PhaeoP66_RS19190	COG0133	tryptophan synthase activity
PhaeoP66_RS19195	COG1522	sequence-specific DNA binding
PhaeoP66_RS19210	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS19240	COG1720	tRNA m6t6A37 methyltransferase activity
PhaeoP66_RS19245	COG0747	negative chemotaxis
PhaeoP66_RS19250	COG0601	transmembrane transport
PhaeoP66_RS19260	COG0444	Belongs to the ABC transporter superfamily
PhaeoP66_RS19265	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
PhaeoP66_RS19280	COG1960	acyl-CoA dehydrogenase activity
PhaeoP66_RS19300	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS19305	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS19310	COG4608	Belongs to the ABC transporter superfamily
PhaeoP66_RS19315	COG0444	Belongs to the ABC transporter superfamily
PhaeoP66_RS19320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PhaeoP66_RS19325	COG0601	transmembrane transport
PhaeoP66_RS19330	COG0747	negative chemotaxis
PhaeoP66_RS19380	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PhaeoP66_RS19385	COG1176	ABC-type spermidine putrescine transport system, permease component I
PhaeoP66_RS19400	COG0588	phosphoglycerate mutase activity
PhaeoP66_RS19425	COG0435	Glutathione S-transferase
PhaeoP66_RS19470	COG0714	Associated with various cellular activities
PhaeoP66_RS19480	COG2010	Cytochrome c
PhaeoP66_RS19495	COG2132	Multicopper oxidase
PhaeoP66_RS19500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PhaeoP66_RS19510	COG2207	Transcriptional regulator
PhaeoP66_RS19545	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS19570	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PhaeoP66_RS19585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PhaeoP66_RS19595	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS19605	COG2207	Transcriptional regulator
PhaeoP66_RS19615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PhaeoP66_RS19615	COG0446	pyridine nucleotide-disulphide oxidoreductase
PhaeoP66_RS19620	COG4311	Sarcosine oxidase, delta subunit
PhaeoP66_RS19625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PhaeoP66_RS19635	COG1024	Enoyl-CoA hydratase
PhaeoP66_RS19640	COG1960	acyl-CoA dehydrogenase activity
PhaeoP66_RS19655	COG0735	belongs to the Fur family
PhaeoP66_RS19665	COG0577	efflux transmembrane transporter activity
PhaeoP66_RS19665	COG1136	(ABC) transporter
PhaeoP66_RS19670	COG0577	efflux transmembrane transporter activity
PhaeoP66_RS19670	COG1136	(ABC) transporter
PhaeoP66_RS19700	COG0745	RESPONSE REGULATOR receiver
PhaeoP66_RS19705	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PhaeoP66_RS19720	COG0745	RESPONSE REGULATOR receiver
PhaeoP66_RS19730	COG0840	transmembrane signaling receptor activity
PhaeoP66_RS19735	COG2201	protein-glutamate methylesterase activity
PhaeoP66_RS19745	COG0725	ABC transporter, periplasmic molybdate-binding protein
PhaeoP66_RS19750	COG4149	molybdate abc transporter
PhaeoP66_RS19755	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PhaeoP66_RS19775	COG0735	belongs to the Fur family
PhaeoP66_RS19785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PhaeoP66_RS19800	COG0574	Belongs to the PEP-utilizing enzyme family
PhaeoP66_RS19800	COG3848	Pyruvate phosphate dikinase
PhaeoP66_RS19810	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PhaeoP66_RS19840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PhaeoP66_RS19855	COG1192	Involved in chromosome partitioning
PhaeoP66_RS19885	COG4974	Belongs to the 'phage' integrase family
PhaeoP66_RS19890	COG0582	viral genome integration into host DNA
PhaeoP66_RS19895	COG4974	Belongs to the 'phage' integrase family
PhaeoP66_RS19970	COG0420	3'-5' exonuclease activity
PhaeoP66_RS20005	COG3843	relaxase mobilization nuclease domain protein
PhaeoP66_RS20010	COG3505	Type IV secretory pathway VirD4
PhaeoP66_RS20045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PhaeoP66_RS20065	COG4962	Type ii secretion system protein e
PhaeoP66_RS20070	COG2948	multi-organism process
PhaeoP66_RS20090	COG1196	nuclear chromosome segregation
PhaeoP66_RS20090	COG0741	lytic transglycosylase activity
PhaeoP66_RS20090	COG0739	heme binding
PhaeoP66_RS20110	COG0739	heme binding
PhaeoP66_RS20110	COG1196	nuclear chromosome segregation
PhaeoP66_RS20110	COG0741	lytic transglycosylase activity
PhaeoP66_RS20150	COG3474	cytochrome
PhaeoP66_RS20210	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PhaeoP66_RS20240	COG2132	Multicopper oxidase
PhaeoP66_RS20265	COG2217	Heavy metal translocating P-type atpase
PhaeoP66_RS20275	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PhaeoP66_RS20275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PhaeoP66_RS20285	COG2132	Multicopper oxidase
PhaeoP66_RS20290	COG2010	Cytochrome c
PhaeoP66_RS20320	COG4235	cytochrome complex assembly
PhaeoP66_RS20325	COG3088	subunit of a heme lyase
PhaeoP66_RS20330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PhaeoP66_RS20335	COG1138	Cytochrome C-type biogenesis protein
PhaeoP66_RS20370	COG0398	Pfam SNARE associated Golgi protein
PhaeoP66_RS20375	COG1230	cation diffusion facilitator family transporter
PhaeoP66_RS20435	COG1742	UPF0060 membrane protein
PhaeoP66_RS20440	COG0789	Transcriptional regulator
PhaeoP66_RS20445	COG1999	signal sequence binding
PhaeoP66_RS20455	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PhaeoP66_RS20455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PhaeoP66_RS20465	COG1999	signal sequence binding
PhaeoP66_RS20485	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PhaeoP66_RS20490	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PhaeoP66_RS20495	COG3034	peptidoglycan biosynthetic process
PhaeoP66_RS20520	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PhaeoP66_RS20525	COG1192	Involved in chromosome partitioning
PhaeoP66_RS20530	COG1475	DNA binding
PhaeoP66_RS20535	COG1414	Transcriptional regulator
PhaeoP66_RS20545	COG1309	transcriptional regulator
PhaeoP66_RS20625	COG4974	Belongs to the 'phage' integrase family
PhaeoP66_RS20630	COG0582	viral genome integration into host DNA
PhaeoP66_RS20635	COG4974	Belongs to the 'phage' integrase family
PhaeoP66_RS20690	COG1073	alpha beta
PhaeoP66_RS20740	COG0811	peptide transport
PhaeoP66_RS20750	COG1629	transport
PhaeoP66_RS20755	COG3720	iron ion transport
PhaeoP66_RS20760	COG4558	Periplasmic binding protein
PhaeoP66_RS20765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PhaeoP66_RS20770	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PhaeoP66_RS20790	COG0464	growth
PhaeoP66_RS20800	COG0784	Response regulator, receiver
PhaeoP66_RS20805	COG3920	Histidine kinase
PhaeoP66_RS20845	COG1017	nitric oxide dioxygenase activity
PhaeoP66_RS20845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PhaeoP66_RS20850	COG2423	ornithine cyclodeaminase activity
PhaeoP66_RS20875	COG2226	methyltransferase
PhaeoP66_RS20875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PhaeoP66_RS20875	COG0596	Alpha beta hydrolase
PhaeoP66_RS20880	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PhaeoP66_RS20890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PhaeoP66_RS20895	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS20900	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS20905	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PhaeoP66_RS20910	COG2855	membrane
PhaeoP66_RS20925	COG2826	transposase and inactivated derivatives, IS30 family
PhaeoP66_RS20975	COG1917	Cupin 2, conserved barrel domain protein
PhaeoP66_RS21010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PhaeoP66_RS21020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PhaeoP66_RS21030	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
PhaeoP66_RS21075	COG1192	Involved in chromosome partitioning
PhaeoP66_RS21080	COG1475	DNA binding
PhaeoP66_RS21085	COG1414	Transcriptional regulator
PhaeoP66_RS21115	COG0297	glycogen (starch) synthase activity
PhaeoP66_RS21120	COG0297	glycogen (starch) synthase activity
PhaeoP66_RS21135	COG4227	nucleotidyltransferase activity
PhaeoP66_RS21180	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS21185	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PhaeoP66_RS21205	COG2267	carboxylic ester hydrolase activity
PhaeoP66_RS21240	COG0318	PFAM AMP-dependent synthetase and ligase
PhaeoP66_RS21250	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
PhaeoP66_RS21265	COG3736	Type IV secretory pathway, component VirB8
PhaeoP66_RS21285	COG0741	lytic transglycosylase activity
PhaeoP66_RS21285	COG0739	heme binding
PhaeoP66_RS21285	COG1196	nuclear chromosome segregation
PhaeoP66_RS21295	COG3451	type IV secretory pathway VirB4
PhaeoP66_RS21330	COG1012	belongs to the aldehyde dehydrogenase family
PhaeoP66_RS21335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PhaeoP66_RS21340	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS21345	COG3842	ATPase activity
PhaeoP66_RS21350	COG0395	ABC-type sugar transport system, permease component
PhaeoP66_RS21355	COG1176	ABC-type spermidine putrescine transport system, permease component I
PhaeoP66_RS21365	COG0579	oxidoreductase
PhaeoP66_RS21385	COG2814	Major facilitator Superfamily
PhaeoP66_RS21405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PhaeoP66_RS21415	COG3246	L-lysine catabolic process to acetate
PhaeoP66_RS21420	COG3485	protocatechuate 3,4-dioxygenase
PhaeoP66_RS21425	COG3485	protocatechuate 3,4-dioxygenase
PhaeoP66_RS21430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PhaeoP66_RS21435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PhaeoP66_RS21445	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS21450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PhaeoP66_RS21460	COG0318	PFAM AMP-dependent synthetase and ligase
PhaeoP66_RS21500	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS21515	COG0433	COG0433 Predicted ATPase
PhaeoP66_RS21540	COG0419	ATPase involved in DNA repair
PhaeoP66_RS21615	COG1192	Involved in chromosome partitioning
PhaeoP66_RS21620	COG1475	DNA binding
PhaeoP66_RS21630	COG2205	protein histidine kinase activity
PhaeoP66_RS21680	COG2197	response regulator
PhaeoP66_RS21685	COG3177	Filamentation induced by cAMP protein fic
PhaeoP66_RS21695	COG1132	(ABC) transporter
PhaeoP66_RS21700	COG1082	Xylose isomerase domain protein TIM barrel
PhaeoP66_RS21710	COG0318	PFAM AMP-dependent synthetase and ligase
PhaeoP66_RS21715	COG4264	IucA IucC family
PhaeoP66_RS21730	COG4607	ABC-type enterochelin transport system periplasmic component
PhaeoP66_RS21735	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PhaeoP66_RS21740	COG4605	iron ion homeostasis
PhaeoP66_RS21745	COG4604	ABC transporter, ATP-binding protein
PhaeoP66_RS21750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PhaeoP66_RS21770	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PhaeoP66_RS21770	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PhaeoP66_RS21775	COG0509	glycine decarboxylation via glycine cleavage system
PhaeoP66_RS21780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PhaeoP66_RS21785	COG1115	amino acid carrier protein
PhaeoP66_RS21790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PhaeoP66_RS21805	COG3002	Belongs to the UPF0753 family
PhaeoP66_RS21810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PhaeoP66_RS21820	COG0673	inositol 2-dehydrogenase activity
PhaeoP66_RS21830	COG3842	ATPase activity
PhaeoP66_RS21840	COG1175	transmembrane transport
PhaeoP66_RS21845	COG1653	transport
PhaeoP66_RS21860	COG0673	inositol 2-dehydrogenase activity
PhaeoP66_RS21910	COG0583	DNA-binding transcription factor activity
PhaeoP66_RS21915	COG2132	Multicopper oxidase
PhaeoP66_RS21920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PhaeoP66_RS21930	COG1192	Involved in chromosome partitioning
PhaeoP66_RS21940	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PhaeoP66_RS21945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PhaeoP66_RS21950	COG1216	Glycosyl transferase, family 2
PhaeoP66_RS22005	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
PhaeoP66_RS22010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PhaeoP66_RS22020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PhaeoP66_RS22040	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
PhaeoP66_RS22090	COG1086	Polysaccharide biosynthesis protein
PhaeoP66_RS22095	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PhaeoP66_RS22110	COG1126	abc transporter atp-binding protein
PhaeoP66_RS22190	COG0739	heme binding
PhaeoP66_RS22190	COG0741	lytic transglycosylase activity
PhaeoP66_RS22190	COG1196	nuclear chromosome segregation
PhaeoP66_RS22205	COG3451	type IV secretory pathway VirB4
PhaeoP66_RS22240	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
PhaeoP66_RS22245	COG3505	Type IV secretory pathway VirD4
PhaeoP66_RS22300	COG4423	Transcription factor
PhaeoP66_RS22305	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
PhaeoP66_RS22360	COG1475	DNA binding
PhaeoP66_RS22370	COG1396	sequence-specific DNA binding
PhaeoP66_RS22405	COG1129	ABC transporter
PhaeoP66_RS22415	COG1172	Belongs to the binding-protein-dependent transport system permease family
PhaeoP66_RS22420	COG1028	Short-chain dehydrogenase reductase Sdr
PhaeoP66_RS22425	COG1879	ABC-type sugar transport system periplasmic component
PhaeoP66_RS22440	COG0006	proline dipeptidase activity
PhaeoP66_RS22445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PhaeoP66_RS22450	COG0022	dehydrogenase e1 component
PhaeoP66_RS22455	COG0508	dehydrogenase complex catalyzes the overall conversion of
PhaeoP66_RS22470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PhaeoP66_RS22530	COG0739	heme binding
PhaeoP66_RS22530	COG1196	nuclear chromosome segregation
PhaeoP66_RS22530	COG0741	lytic transglycosylase activity
PhaeoP66_RS22555	COG0741	lytic transglycosylase activity
PhaeoP66_RS22555	COG0739	heme binding
PhaeoP66_RS22555	COG1196	nuclear chromosome segregation
PhaeoP66_RS22575	COG2948	multi-organism process
PhaeoP66_RS22580	COG4962	Type ii secretion system protein e
PhaeoP66_RS22645	COG4974	Belongs to the 'phage' integrase family
PhaeoP66_RS22650	COG0582	viral genome integration into host DNA
PhaeoP66_RS22655	COG4974	Belongs to the 'phage' integrase family
PhaeoP66_RS22665	COG0659	secondary active sulfate transmembrane transporter activity
PhaeoP66_RS22670	COG0589	response to stress
PhaeoP66_RS22695	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
PhaeoP66_RS22790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PhaeoP66_RS22890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs