locus-tag	class	description
PBPR_RS00005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PBPR_RS00010	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PBPR_RS00015	COG0706	membrane insertase activity
PBPR_RS00020	COG0594	ribonuclease P activity
PBPR_RS00025	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PBPR_RS00030	COG1126	abc transporter atp-binding protein
PBPR_RS00045	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PBPR_RS00050	COG0592	DNA-directed DNA polymerase activity
PBPR_RS00055	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PBPR_RS00060	COG0187	DNA topoisomerase II activity
PBPR_RS00080	COG1987	bacterial-type flagellum assembly
PBPR_RS00110	COG1677	Flagellar hook-basal body complex protein FliE
PBPR_RS00120	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PBPR_RS00155	COG1815	bacterial-type flagellum-dependent cell motility
PBPR_RS00160	COG1558	bacterial-type flagellum-dependent cell motility
PBPR_RS00175	COG4786	Flagellar basal body rod
PBPR_RS00180	COG4786	Flagellar basal body rod
PBPR_RS00185	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PBPR_RS00190	COG1706	bacterial-type flagellum-dependent cell motility
PBPR_RS00205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PBPR_RS00215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PBPR_RS00220	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PBPR_RS00225	COG1516	flagellar protein fliS
PBPR_RS00240	COG1580	Controls the rotational direction of flagella during chemotaxis
PBPR_RS00245	COG1191	sigma factor activity
PBPR_RS00250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PBPR_RS00255	COG1360	Flagellar Motor Protein
PBPR_RS00280	COG3977	Valine--pyruvate aminotransferase
PBPR_RS00285	COG0751	glycine-tRNA ligase activity
PBPR_RS00290	COG0752	glycyl-tRNA synthetase alpha subunit
PBPR_RS00295	COG2885	chlorophyll binding
PBPR_RS00300	COG2119	membrane
PBPR_RS00310	COG0425	Belongs to the sulfur carrier protein TusA family
PBPR_RS00325	COG0604	alcohol dehydrogenase
PBPR_RS00330	COG0183	Belongs to the thiolase family
PBPR_RS00335	COG1024	Enoyl-CoA hydratase
PBPR_RS00335	COG1250	3-hydroxyacyl-CoA dehydrogenase
PBPR_RS00340	COG1739	Uncharacterized protein family UPF0029
PBPR_RS00345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PBPR_RS00405	COG3335	DDE superfamily endonuclease
PBPR_RS00420	COG3335	DDE superfamily endonuclease
PBPR_RS00435	COG0583	DNA-binding transcription factor activity
PBPR_RS00440	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PBPR_RS00445	COG2960	long-chain fatty acid transporting porin activity
PBPR_RS00450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PBPR_RS00460	COG1309	transcriptional regulator
PBPR_RS00505	COG0747	negative chemotaxis
PBPR_RS00510	COG0601	transmembrane transport
PBPR_RS00515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PBPR_RS00525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PBPR_RS00535	COG0589	response to stress
PBPR_RS00540	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PBPR_RS00545	COG0352	thiamine-phosphate diphosphorylase activity
PBPR_RS00550	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PBPR_RS00560	COG2022	thiamine diphosphate biosynthetic process
PBPR_RS00570	COG0006	proline dipeptidase activity
PBPR_RS00570	COG0006	proline dipeptidase activity
PBPR_RS00590	COG1322	Protein conserved in bacteria
PBPR_RS00595	COG2226	methyltransferase
PBPR_RS00600	COG3165	ubiquinone biosynthetic process from chorismate
PBPR_RS00605	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PBPR_RS00610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PBPR_RS00615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PBPR_RS00620	COG0805	protein transport
PBPR_RS00635	COG0697	spore germination
PBPR_RS00640	COG0589	response to stress
PBPR_RS00645	COG1528	Iron-storage protein
PBPR_RS00655	COG0668	transmembrane transport
PBPR_RS00660	COG2081	HI0933 family
PBPR_RS00680	COG3148	PFAM DTW domain containing protein
PBPR_RS00695	COG0561	phosphatase activity
PBPR_RS00700	COG2267	carboxylic ester hydrolase activity
PBPR_RS00705	COG1280	lysine exporter protein (LysE YggA)
PBPR_RS00710	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
PBPR_RS00720	COG0583	DNA-binding transcription factor activity
PBPR_RS00725	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
PBPR_RS00730	COG4221	oxidoreductase activity
PBPR_RS00750	COG3714	YhhN family
PBPR_RS00765	COG2095	MarC family integral membrane protein
PBPR_RS00775	COG0742	ribosomal rna small subunit methyltransferase
PBPR_RS00780	COG0552	protein localization to endoplasmic reticulum
PBPR_RS00780	COG0552	protein localization to endoplasmic reticulum
PBPR_RS00785	COG2884	Cell division ATP-binding protein ftsE
PBPR_RS00790	COG2177	Part of the ABC transporter FtsEX involved in
PBPR_RS00800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBPR_RS00810	COG2271	Major facilitator Superfamily
PBPR_RS00815	COG1349	DNA-binding transcription factor activity
PBPR_RS00820	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PBPR_RS00830	COG3161	chorismate lyase activity
PBPR_RS00835	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PBPR_RS00845	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PBPR_RS00855	COG1565	acr, cog1565
PBPR_RS00855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PBPR_RS00860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PBPR_RS00865	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PBPR_RS00895	COG0109	protoheme IX farnesyltransferase activity
PBPR_RS00900	COG0534	Mate efflux family protein
PBPR_RS00910	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PBPR_RS00910	COG0316	Belongs to the HesB IscA family
PBPR_RS00920	COG0596	Alpha beta hydrolase
PBPR_RS00935	COG2183	response to ionizing radiation
PBPR_RS00940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PBPR_RS00955	COG2233	PERMEase
PBPR_RS00960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PBPR_RS00965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PBPR_RS00970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PBPR_RS00975	COG1758	RNA polymerase activity
PBPR_RS00980	COG0194	GDP metabolic process
PBPR_RS00995	COG0653	protein targeting
PBPR_RS01015	COG1561	YicC-like family, N-terminal region
PBPR_RS01020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PBPR_RS01025	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PBPR_RS01030	COG1309	transcriptional regulator
PBPR_RS01035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PBPR_RS01040	COG2003	Belongs to the UPF0758 family
PBPR_RS01045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PBPR_RS01050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PBPR_RS01060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PBPR_RS01070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PBPR_RS01075	COG0859	PFAM glycosyl transferase family 9
PBPR_RS01080	COG3642	lipopolysaccharide core region biosynthetic process
PBPR_RS01085	COG1519	Transferase
PBPR_RS01095	COG0463	Glycosyl transferase, family 2
PBPR_RS01110	COG0438	transferase activity, transferring glycosyl groups
PBPR_RS01125	COG1560	Kdo2-lipid A biosynthetic process
PBPR_RS01145	COG4942	peptidase
PBPR_RS01150	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PBPR_RS01155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBPR_RS01160	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PBPR_RS01165	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PBPR_RS01170	COG1045	serine acetyltransferase
PBPR_RS01175	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PBPR_RS01180	COG2205	protein histidine kinase activity
PBPR_RS01195	COG0205	6-phosphofructokinase activity
PBPR_RS01200	COG0149	triose-phosphate isomerase activity
PBPR_RS01225	COG1494	fructose-1,6-bisphosphatase
PBPR_RS01265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PBPR_RS01270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PBPR_RS01275	COG3074	FtsZ-dependent cytokinesis
PBPR_RS01280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PBPR_RS01285	COG1575	Belongs to the MenA family. Type 1 subfamily
PBPR_RS01290	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PBPR_RS01295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PBPR_RS01305	COG1609	Transcriptional regulator
PBPR_RS01310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PBPR_RS01315	COG0254	rRNA binding
PBPR_RS01320	COG0281	malic enzyme
PBPR_RS01325	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
PBPR_RS01330	COG0626	cystathionine gamma-synthase activity
PBPR_RS01335	COG0460	homoserine dehydrogenase
PBPR_RS01335	COG0527	aspartate kinase activity
PBPR_RS01340	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PBPR_RS01345	COG1695	Transcriptional regulator
PBPR_RS01350	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PBPR_RS01360	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PBPR_RS01365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PBPR_RS01370	COG0137	argininosuccinate synthase activity
PBPR_RS01375	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PBPR_RS01375	COG0165	Argininosuccinate lyase
PBPR_RS01390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PBPR_RS01390	COG0678	peroxiredoxin activity
PBPR_RS01400	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PBPR_RS01430	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PBPR_RS01435	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PBPR_RS01445	COG0338	D12 class N6 adenine-specific DNA methyltransferase
PBPR_RS01455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PBPR_RS01460	COG0546	phosphoglycolate phosphatase activity
PBPR_RS01465	COG0180	Tryptophanyl-tRNA synthetase
PBPR_RS01480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PBPR_RS01490	COG1012	belongs to the aldehyde dehydrogenase family
PBPR_RS01510	COG1765	OsmC-like protein
PBPR_RS01515	COG3954	Phosphoribulokinase
PBPR_RS01525	COG0429	hydrolase of the alpha beta-hydrolase fold
PBPR_RS01530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PBPR_RS01545	COG0488	(ABC) transporter
PBPR_RS01550	COG2249	NAD(P)H dehydrogenase (quinone) activity
PBPR_RS01560	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
PBPR_RS01565	COG1047	Peptidyl-prolyl cis-trans
PBPR_RS01570	COG2900	Belongs to the SlyX family
PBPR_RS01580	COG0545	Peptidyl-prolyl cis-trans isomerase
PBPR_RS01585	COG2964	Protein conserved in bacteria
PBPR_RS01590	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PBPR_RS01595	COG2923	Belongs to the DsrF TusC family
PBPR_RS01605	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PBPR_RS01610	COG0049	tRNA binding
PBPR_RS01615	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PBPR_RS01620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PBPR_RS01635	COG0051	transcription antitermination factor activity, RNA binding
PBPR_RS01640	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PBPR_RS01645	COG0088	Forms part of the polypeptide exit tunnel
PBPR_RS01650	COG0089	rRNA binding
PBPR_RS01655	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PBPR_RS01660	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PBPR_RS01665	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PBPR_RS01670	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PBPR_RS01675	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PBPR_RS01680	COG0255	Belongs to the universal ribosomal protein uL29 family
PBPR_RS01685	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PBPR_RS01690	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PBPR_RS01695	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PBPR_RS01700	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PBPR_RS01705	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PBPR_RS01710	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PBPR_RS01715	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PBPR_RS01720	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PBPR_RS01725	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PBPR_RS01730	COG1841	ribosomal large subunit assembly
PBPR_RS01735	COG0200	Binds to the 23S rRNA
PBPR_RS01740	COG0201	protein transport
PBPR_RS01745	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PBPR_RS01750	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PBPR_RS01755	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PBPR_RS01760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PBPR_RS01765	COG0202	RNA polymerase activity
PBPR_RS01770	COG0203	ribosomal protein L17
PBPR_RS01775	COG0438	transferase activity, transferring glycosyl groups
PBPR_RS01800	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PBPR_RS01880	COG3335	DDE superfamily endonuclease
PBPR_RS01890	COG3335	DDE superfamily endonuclease
PBPR_RS01900	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
PBPR_RS01920	COG1136	(ABC) transporter
PBPR_RS01930	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
PBPR_RS01940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PBPR_RS01945	COG0729	surface antigen
PBPR_RS01965	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PBPR_RS01970	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PBPR_RS01975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PBPR_RS01980	COG0163	prenyltransferase activity
PBPR_RS01995	COG2358	TRAP transporter, solute receptor (TAXI family
PBPR_RS02000	COG1438	arginine binding
PBPR_RS02005	COG0039	L-malate dehydrogenase activity
PBPR_RS02020	COG0142	geranyltranstransferase activity
PBPR_RS02025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PBPR_RS02030	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PBPR_RS02035	COG0697	spore germination
PBPR_RS02040	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PBPR_RS02045	COG2966	Psort location CytoplasmicMembrane, score
PBPR_RS02050	COG3610	response to peptide
PBPR_RS02060	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PBPR_RS02065	COG2967	ApaG domain
PBPR_RS02070	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PBPR_RS02075	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PBPR_RS02080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PBPR_RS02085	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PBPR_RS02090	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PBPR_RS02095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PBPR_RS02100	COG0564	pseudouridine synthase activity
PBPR_RS02105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PBPR_RS02110	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PBPR_RS02115	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
PBPR_RS02125	COG4143	(ABC) transporter
PBPR_RS02140	COG0066	3-isopropylmalate dehydratase activity
PBPR_RS02145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PBPR_RS02150	COG0473	3-isopropylmalate dehydrogenase activity
PBPR_RS02155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PBPR_RS02165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBPR_RS02175	COG0583	DNA-binding transcription factor activity
PBPR_RS02180	COG1022	Amp-dependent synthetase and ligase
PBPR_RS02185	COG0028	Belongs to the TPP enzyme family
PBPR_RS02205	COG0469	pyruvate kinase activity
PBPR_RS02220	COG0358	DNA primase activity
PBPR_RS02225	COG1610	YqeY-like protein
PBPR_RS02230	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PBPR_RS02235	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PBPR_RS02240	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PBPR_RS02245	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PBPR_RS02250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PBPR_RS02255	COG1968	undecaprenyl-diphosphatase activity
PBPR_RS02260	COG0617	tRNA 3'-terminal CCA addition
PBPR_RS02265	COG3267	Type II secretory pathway component ExeA
PBPR_RS02265	COG3409	Peptidoglycan-binding domain 1 protein
PBPR_RS02275	COG4991	sh3 domain protein
PBPR_RS02280	COG0306	phosphate transporter
PBPR_RS02285	COG1392	Phosphate transport regulator
PBPR_RS02290	COG3025	triphosphatase activity
PBPR_RS02295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PBPR_RS02305	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PBPR_RS02310	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PBPR_RS02310	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PBPR_RS02315	COG1538	Outer membrane efflux protein
PBPR_RS02320	COG0494	nUDIX hydrolase
PBPR_RS02325	COG3151	Protein conserved in bacteria
PBPR_RS02335	COG3150	esterase
PBPR_RS02345	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PBPR_RS02350	COG2115	Belongs to the xylose isomerase family
PBPR_RS02355	COG2211	Major facilitator Superfamily
PBPR_RS02360	COG2017	converts alpha-aldose to the beta-anomer
PBPR_RS02375	COG4213	ABC transporter substrate-binding protein
PBPR_RS02380	COG1129	ABC transporter
PBPR_RS02385	COG4214	carbohydrate transport
PBPR_RS02395	COG1070	Carbohydrate kinase
PBPR_RS02400	COG0204	Acyl-transferase
PBPR_RS02405	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
PBPR_RS02410	COG0251	oxidation-reduction process
PBPR_RS02415	COG1438	arginine binding
PBPR_RS02420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PBPR_RS02425	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
PBPR_RS02430	COG0540	Belongs to the ATCase OTCase family
PBPR_RS02435	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PBPR_RS02450	COG1288	antiporter activity
PBPR_RS02455	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
PBPR_RS02460	COG3250	beta-galactosidase activity
PBPR_RS02465	COG0456	acetyltransferase
PBPR_RS02475	COG0525	valine-tRNA ligase activity
PBPR_RS02480	COG2927	DNA polymerase III (CHI subunit)
PBPR_RS02485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PBPR_RS02490	COG0795	lipopolysaccharide-transporting ATPase activity
PBPR_RS02495	COG0795	lipopolysaccharide-transporting ATPase activity
PBPR_RS02530	COG0726	polysaccharide deacetylase
PBPR_RS02540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PBPR_RS02545	COG1486	melibiose metabolic process
PBPR_RS02550	COG3394	polysaccharide catabolic process
PBPR_RS02560	COG2979	Protein of unknown function (DUF533)
PBPR_RS02605	COG2801	Transposase and inactivated derivatives
PBPR_RS02615	COG3335	DDE superfamily endonuclease
PBPR_RS02635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PBPR_RS02650	COG2971	BadF BadG BcrA BcrD
PBPR_RS02660	COG4608	Belongs to the ABC transporter superfamily
PBPR_RS02665	COG0444	Belongs to the ABC transporter superfamily
PBPR_RS02670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PBPR_RS02685	COG0784	Response regulator, receiver
PBPR_RS02685	COG2205	protein histidine kinase activity
PBPR_RS02690	COG2813	Specifically methylates the guanine in position
PBPR_RS02695	COG0628	permease
PBPR_RS02700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PBPR_RS02705	COG0038	chloride channel
PBPR_RS02710	COG0316	Belongs to the HesB IscA family
PBPR_RS02715	COG0739	heme binding
PBPR_RS02720	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PBPR_RS02730	COG2860	membrane
PBPR_RS02735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PBPR_RS02745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PBPR_RS02750	COG0493	'glutamate synthase
PBPR_RS02755	COG0067	glutamate synthase
PBPR_RS02755	COG0070	glutamate synthase
PBPR_RS02755	COG0069	glutamate synthase activity
PBPR_RS02765	COG0069	glutamate synthase activity
PBPR_RS02765	COG0070	glutamate synthase
PBPR_RS02765	COG0067	glutamate synthase
PBPR_RS02770	COG1242	4 iron, 4 sulfur cluster binding
PBPR_RS02775	COG5001	Diguanylate cyclase
PBPR_RS02775	COG4251	negative regulation of phosphorylation
PBPR_RS02775	COG3706	GGDEF domain
PBPR_RS02775	COG2203	Gaf domain
PBPR_RS02780	COG5002	protein histidine kinase activity
PBPR_RS02780	COG2198	Histidine kinase
PBPR_RS02780	COG0784	Response regulator, receiver
PBPR_RS02790	COG0745	RESPONSE REGULATOR receiver
PBPR_RS02800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PBPR_RS02810	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PBPR_RS02820	COG0083	homoserine kinase activity
PBPR_RS02825	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PBPR_RS02835	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
PBPR_RS02840	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PBPR_RS02860	COG1115	amino acid carrier protein
PBPR_RS02865	COG3022	response to hydroperoxide
PBPR_RS02870	COG0513	Belongs to the DEAD box helicase family
PBPR_RS02875	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PBPR_RS02890	COG4974	Belongs to the 'phage' integrase family
PBPR_RS02895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PBPR_RS02900	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PBPR_RS02905	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PBPR_RS02910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PBPR_RS02915	COG1301	dicarboxylic acid transport
PBPR_RS02920	COG2204	response regulator
PBPR_RS02930	COG0667	Aldo Keto reductase
PBPR_RS02940	COG3066	DNA modification
PBPR_RS02945	COG0494	nUDIX hydrolase
PBPR_RS02955	COG0730	response to heat
PBPR_RS02960	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PBPR_RS02965	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PBPR_RS02970	COG1283	sodium-dependent phosphate transmembrane transporter activity
PBPR_RS02975	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PBPR_RS02985	COG0583	DNA-binding transcription factor activity
PBPR_RS02990	COG0640	Transcriptional regulator
PBPR_RS02995	COG0268	Binds directly to 16S ribosomal RNA
PBPR_RS03005	COG0196	riboflavin kinase activity
PBPR_RS03010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PBPR_RS03015	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PBPR_RS03020	COG1047	Peptidyl-prolyl cis-trans
PBPR_RS03025	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PBPR_RS03030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PBPR_RS03035	COG0505	Belongs to the CarA family
PBPR_RS03040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PBPR_RS03045	COG2239	Acts as a magnesium transporter
PBPR_RS03050	COG2027	D-alanyl-D-alanine carboxypeptidase
PBPR_RS03055	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PBPR_RS03060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PBPR_RS03065	COG1534	Rna-binding protein
PBPR_RS03070	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PBPR_RS03075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PBPR_RS03080	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PBPR_RS03090	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PBPR_RS03105	COG0779	Required for maturation of 30S ribosomal subunits
PBPR_RS03110	COG0195	Participates in both transcription termination and antitermination
PBPR_RS03115	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PBPR_RS03120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PBPR_RS03125	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PBPR_RS03130	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PBPR_RS03135	COG1185	polyribonucleotide nucleotidyltransferase activity
PBPR_RS03145	COG0826	peptidase U32
PBPR_RS03150	COG0826	peptidase U32
PBPR_RS03160	COG3154	lipid carrier protein
PBPR_RS03175	COG0456	acetyltransferase
PBPR_RS03195	COG0084	hydrolase, TatD family'
PBPR_RS03200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PBPR_RS03205	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PBPR_RS03210	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PBPR_RS03215	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PBPR_RS03220	COG0813	purine-nucleoside phosphorylase activity
PBPR_RS03225	COG3726	membrane protein affecting hemolysin expression
PBPR_RS03230	COG0560	Phosphoserine phosphatase
PBPR_RS03240	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PBPR_RS03245	COG0739	heme binding
PBPR_RS03255	COG0488	(ABC) transporter
PBPR_RS03260	COG0741	lytic transglycosylase activity
PBPR_RS03265	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
PBPR_RS03270	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
PBPR_RS03280	COG3279	Response regulator of the LytR AlgR family
PBPR_RS03285	COG3275	phosphorelay sensor kinase activity
PBPR_RS03305	COG1136	(ABC) transporter
PBPR_RS03325	COG0739	heme binding
PBPR_RS03340	COG2815	serine threonine protein kinase
PBPR_RS03340	COG0515	serine threonine protein kinase
PBPR_RS03375	COG0631	protein serine/threonine phosphatase activity
PBPR_RS03445	COG3209	COG3209 Rhs family protein
PBPR_RS03510	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PBPR_RS03515	COG2867	negative regulation of translational initiation
PBPR_RS03520	COG2914	Belongs to the UPF0125 (RnfH) family
PBPR_RS03525	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PBPR_RS03530	COG0497	DNA recombination
PBPR_RS03535	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PBPR_RS03540	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PBPR_RS03545	COG0443	Heat shock 70 kDa protein
PBPR_RS03550	COG0484	heat shock protein binding
PBPR_RS03625	COG3335	DDE superfamily endonuclease
PBPR_RS03635	COG2390	Transcriptional regulator
PBPR_RS03645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PBPR_RS03650	COG0826	peptidase U32
PBPR_RS03655	COG2974	May be involved in recombination
PBPR_RS03660	COG0420	3'-5' exonuclease activity
PBPR_RS03675	COG5002	protein histidine kinase activity
PBPR_RS03690	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PBPR_RS03705	COG0581	inorganic phosphate transmembrane transporter activity
PBPR_RS03710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PBPR_RS03715	COG0704	Plays a role in the regulation of phosphate uptake
PBPR_RS03730	COG3142	Participates in the control of copper homeostasis
PBPR_RS03735	COG0450	alkyl hydroperoxide reductase
PBPR_RS03740	COG0583	DNA-binding transcription factor activity
PBPR_RS03745	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PBPR_RS03755	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
PBPR_RS03760	COG0516	GMP reductase activity
PBPR_RS03760	COG0517	IMP dehydrogenase activity
PBPR_RS03770	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PBPR_RS03775	COG0343	queuine tRNA-ribosyltransferase activity
PBPR_RS03780	COG1862	Preprotein translocase
PBPR_RS03785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PBPR_RS03790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PBPR_RS03795	COG0483	inositol monophosphate 1-phosphatase activity
PBPR_RS03805	COG1959	2 iron, 2 sulfur cluster binding
PBPR_RS03810	COG1104	cysteine desulfurase activity
PBPR_RS03815	COG0822	iron-sulfur transferase activity
PBPR_RS03820	COG0316	Belongs to the HesB IscA family
PBPR_RS03825	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PBPR_RS03830	COG0443	Heat shock 70 kDa protein
PBPR_RS03840	COG2975	iron-sulfur cluster assembly
PBPR_RS03845	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PBPR_RS03855	COG0105	UTP biosynthetic process
PBPR_RS03860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PBPR_RS03865	COG3063	Type IV pilus biogenesis stability protein PilW
PBPR_RS03875	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PBPR_RS03880	COG0124	histidyl-tRNA synthetase
PBPR_RS03885	COG2976	Protein conserved in bacteria
PBPR_RS03890	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PBPR_RS03895	COG1160	GTP binding
PBPR_RS03905	COG1609	Transcriptional regulator
PBPR_RS03925	COG0643	Histidine kinase
PBPR_RS03925	COG2198	Histidine kinase
PBPR_RS03930	COG0835	chemotaxis
PBPR_RS03940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PBPR_RS03945	COG2201	protein-glutamate methylesterase activity
PBPR_RS03950	COG1570	exodeoxyribonuclease VII activity
PBPR_RS03955	COG0517	IMP dehydrogenase activity
PBPR_RS03955	COG0516	GMP reductase activity
PBPR_RS03960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PBPR_RS03960	COG0519	Catalyzes the synthesis of GMP from XMP
PBPR_RS03965	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
PBPR_RS03985	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PBPR_RS03990	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PBPR_RS03990	COG0047	phosphoribosylformylglycinamidine synthase activity
PBPR_RS04025	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PBPR_RS04030	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PBPR_RS04035	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PBPR_RS04035	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PBPR_RS04050	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PBPR_RS04055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PBPR_RS04065	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PBPR_RS04075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PBPR_RS04080	COG0142	geranyltranstransferase activity
PBPR_RS04085	COG1722	exodeoxyribonuclease VII activity
PBPR_RS04090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PBPR_RS04095	COG1360	Flagellar Motor Protein
PBPR_RS04095	COG1360	Flagellar Motor Protein
PBPR_RS04100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBPR_RS04100	COG0301	tRNA thio-modification
PBPR_RS04110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PBPR_RS04120	COG3248	Nucleoside-binding outer membrane protein
PBPR_RS04125	COG2211	Major facilitator Superfamily
PBPR_RS04135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PBPR_RS04145	COG2813	Specifically methylates the guanine in position
PBPR_RS04150	COG0271	Belongs to the BolA IbaG family
PBPR_RS04155	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PBPR_RS04165	COG1805	sodium ion transport
PBPR_RS04175	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PBPR_RS04180	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PBPR_RS04185	COG2871	sodium ion transport
PBPR_RS04190	COG1477	protein flavinylation
PBPR_RS04205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PBPR_RS04210	COG2195	Cleaves the N-terminal amino acid of tripeptides
PBPR_RS04220	COG2252	PERMEase
PBPR_RS04225	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
PBPR_RS04230	COG1073	alpha beta
PBPR_RS04240	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PBPR_RS04245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PBPR_RS04265	COG1876	peptidase activity
PBPR_RS04270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PBPR_RS04275	COG1393	Belongs to the ArsC family
PBPR_RS04295	COG2197	response regulator
PBPR_RS04300	COG3850	Histidine kinase
PBPR_RS04305	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PBPR_RS04315	COG0243	molybdopterin cofactor binding
PBPR_RS04325	COG3005	denitrification pathway
PBPR_RS04355	COG2837	iron assimilation
PBPR_RS04360	COG2190	(PTS) system
PBPR_RS04365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PBPR_RS04370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PBPR_RS04385	COG3115	cell septum assembly
PBPR_RS04390	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PBPR_RS04405	COG5433	transposase activity
PBPR_RS04430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PBPR_RS04445	COG0582	viral genome integration into host DNA
PBPR_RS04520	COG1162	GTPase activity
PBPR_RS04555	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
PBPR_RS04560	COG0835	chemotaxis
PBPR_RS04560	COG0784	Response regulator, receiver
PBPR_RS04565	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PBPR_RS04570	COG1815	bacterial-type flagellum-dependent cell motility
PBPR_RS04575	COG1558	bacterial-type flagellum-dependent cell motility
PBPR_RS04585	COG1749	Flagellar hook protein flgE
PBPR_RS04590	COG4787	bacterial-type flagellum-dependent cell motility
PBPR_RS04600	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PBPR_RS04605	COG1706	bacterial-type flagellum-dependent cell motility
PBPR_RS04610	COG1705	Flagellar rod assembly protein muramidase FlgJ
PBPR_RS04610	COG3951	Flagellar rod assembly protein muramidase FlgJ
PBPR_RS04620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PBPR_RS04630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PBPR_RS04635	COG1334	flagellar protein FlaG
PBPR_RS04640	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PBPR_RS04650	COG1516	flagellar protein fliS
PBPR_RS04675	COG1677	Flagellar hook-basal body complex protein FliE
PBPR_RS04680	COG1766	The M ring may be actively involved in energy transduction
PBPR_RS04685	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PBPR_RS04710	COG1580	Controls the rotational direction of flagella during chemotaxis
PBPR_RS04735	COG1987	bacterial-type flagellum assembly
PBPR_RS04740	COG1684	flagellar biosynthetic protein fliR
PBPR_RS04745	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PBPR_RS04775	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PBPR_RS04780	COG0643	Histidine kinase
PBPR_RS04780	COG2198	Histidine kinase
PBPR_RS04780	COG0784	Response regulator, receiver
PBPR_RS04785	COG2201	protein-glutamate methylesterase activity
PBPR_RS04790	COG1192	Involved in chromosome partitioning
PBPR_RS04800	COG0835	chemotaxis
PBPR_RS04810	COG4133	protoheme IX ABC transporter activity
PBPR_RS04815	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PBPR_RS04820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PBPR_RS04830	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PBPR_RS04835	COG1138	Cytochrome C-type biogenesis protein
PBPR_RS04840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBPR_RS04850	COG4235	cytochrome complex assembly
PBPR_RS04850	COG3088	subunit of a heme lyase
PBPR_RS04855	COG2853	Lipoprotein
PBPR_RS04860	COG2067	long-chain fatty acid transport protein
PBPR_RS04865	COG2067	long-chain fatty acid transport protein
PBPR_RS04880	COG0183	Belongs to the thiolase family
PBPR_RS04885	COG1024	Enoyl-CoA hydratase
PBPR_RS04885	COG1250	3-hydroxyacyl-CoA dehydrogenase
PBPR_RS04895	COG2062	phosphohistidine phosphatase, SixA
PBPR_RS04905	COG2840	Smr protein MutS2
PBPR_RS04910	COG2890	protein-(glutamine-N5) methyltransferase activity
PBPR_RS04915	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PBPR_RS04920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PBPR_RS04925	COG1522	sequence-specific DNA binding
PBPR_RS04930	COG1132	(ABC) transporter
PBPR_RS04935	COG1132	(ABC) transporter
PBPR_RS04940	COG1946	Acyl-CoA thioesterase
PBPR_RS04990	COG2132	Multicopper oxidase
PBPR_RS05010	COG5002	protein histidine kinase activity
PBPR_RS05080	COG2205	protein histidine kinase activity
PBPR_RS05095	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PBPR_RS05120	COG1846	Transcriptional regulator
PBPR_RS05130	COG1199	ATP-dependent helicase activity
PBPR_RS05135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PBPR_RS05140	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
PBPR_RS05155	COG2832	Protein of unknown function (DUF454)
PBPR_RS05160	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PBPR_RS05165	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PBPR_RS05170	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PBPR_RS05175	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PBPR_RS05190	COG3710	Transcriptional regulator
PBPR_RS05195	COG0326	Molecular chaperone. Has ATPase activity
PBPR_RS05200	COG0563	adenylate kinase activity
PBPR_RS05205	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PBPR_RS05210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PBPR_RS05215	COG0367	asparagine synthase
PBPR_RS05225	COG1846	Transcriptional regulator
PBPR_RS05225	COG1940	carbohydrate kinase activity
PBPR_RS05230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PBPR_RS05235	COG0363	glucosamine-6-phosphate deaminase activity
PBPR_RS05240	COG1263	PTS System
PBPR_RS05240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PBPR_RS05250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PBPR_RS05270	COG0596	Alpha beta hydrolase
PBPR_RS05275	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
PBPR_RS05280	COG0033	Phosphoglucomutase
PBPR_RS05295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PBPR_RS05305	COG2009	succinate dehydrogenase
PBPR_RS05310	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PBPR_RS05315	COG1053	succinate dehydrogenase
PBPR_RS05325	COG0567	Dehydrogenase, E1 component
PBPR_RS05330	COG0508	dehydrogenase complex catalyzes the overall conversion of
PBPR_RS05335	COG0045	succinate-CoA ligase (ADP-forming) activity
PBPR_RS05350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PBPR_RS05355	COG1121	(ABC) transporter
PBPR_RS05365	COG0739	heme binding
PBPR_RS05395	COG3706	GGDEF domain
PBPR_RS05400	COG0018	arginyl-trna synthetase
PBPR_RS05405	COG3102	Protein conserved in bacteria
PBPR_RS05410	COG0788	formyltetrahydrofolate deformylase activity
PBPR_RS05430	COG1199	ATP-dependent helicase activity
PBPR_RS05435	COG1214	PFAM Peptidase M22, glycoprotease
PBPR_RS05455	COG0318	PFAM AMP-dependent synthetase and ligase
PBPR_RS05460	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PBPR_RS05465	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PBPR_RS05470	COG2894	cell division
PBPR_RS05475	COG0850	regulation of cytokinetic process
PBPR_RS05480	COG3100	YcgL domain-containing protein
PBPR_RS05485	COG2951	lytic endotransglycosylase activity
PBPR_RS05490	COG2916	Histone family protein nucleoid-structuring protein H-NS
PBPR_RS05495	COG1757	Na H antiporter
PBPR_RS05500	COG1435	thymidine kinase activity
PBPR_RS05505	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PBPR_RS05505	COG0140	phosphoribosyl-ATP diphosphatase activity
PBPR_RS05510	COG0107	imidazoleglycerol-phosphate synthase activity
PBPR_RS05515	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PBPR_RS05520	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PBPR_RS05525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PBPR_RS05525	COG0131	Imidazoleglycerol-phosphate dehydratase
PBPR_RS05530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PBPR_RS05535	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PBPR_RS05540	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PBPR_RS05550	COG3012	SEC-C Motif Domain Protein
PBPR_RS05555	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
PBPR_RS05565	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBPR_RS05570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PBPR_RS05575	COG0215	cysteine-tRNA ligase activity
PBPR_RS05580	COG0584	glycerophosphoryl diester phosphodiesterase
PBPR_RS05585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PBPR_RS05590	COG2095	MarC family integral membrane protein
PBPR_RS05595	COG1454	alcohol dehydrogenase
PBPR_RS05595	COG1012	belongs to the aldehyde dehydrogenase family
PBPR_RS05600	COG1028	Short-chain dehydrogenase reductase Sdr
PBPR_RS05620	COG4067	protein conserved in archaea
PBPR_RS05620	COG0189	ligase activity
PBPR_RS05625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PBPR_RS05630	COG2226	methyltransferase
PBPR_RS05635	COG1801	Protein of unknown function DUF72
PBPR_RS05640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PBPR_RS05645	COG0217	transcriptional regulatory protein
PBPR_RS05650	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PBPR_RS05655	COG0840	transmembrane signaling receptor activity
PBPR_RS05660	COG0632	four-way junction helicase activity
PBPR_RS05665	COG2255	four-way junction helicase activity
PBPR_RS05670	COG0556	nucleotide-excision repair
PBPR_RS05675	COG2204	response regulator
PBPR_RS05680	COG2198	Histidine kinase
PBPR_RS05685	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PBPR_RS05705	COG0315	cyclic pyranopterin monophosphate synthase activity
PBPR_RS05710	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PBPR_RS05715	COG0314	molybdopterin synthase activity
PBPR_RS05720	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PBPR_RS05725	COG0789	Transcriptional regulator
PBPR_RS05735	COG0601	transmembrane transport
PBPR_RS05740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PBPR_RS05755	COG0840	transmembrane signaling receptor activity
PBPR_RS05760	COG2199	diguanylate cyclase activity
PBPR_RS05770	COG2850	peptidyl-arginine hydroxylation
PBPR_RS05785	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PBPR_RS05785	COG2885	chlorophyll binding
PBPR_RS05790	COG0446	pyridine nucleotide-disulphide oxidoreductase
PBPR_RS05795	COG1773	rubredoxin
PBPR_RS05795	COG0426	domain, Protein
PBPR_RS05800	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PBPR_RS05805	COG2915	High frequency lysogenization protein hflD homolog
PBPR_RS05810	COG0482	sulfurtransferase activity
PBPR_RS05815	COG1187	pseudouridine synthase activity
PBPR_RS05820	COG0538	isocitrate dehydrogenase activity
PBPR_RS05825	COG1278	Cold shock
PBPR_RS05830	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PBPR_RS05835	COG0542	response to heat
PBPR_RS05840	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PBPR_RS05845	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PBPR_RS05850	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PBPR_RS05860	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PBPR_RS05865	COG4988	ABC transporter
PBPR_RS05870	COG0492	ferredoxin-NADP+ reductase activity
PBPR_RS05875	COG0686	Belongs to the AlaDH PNT family
PBPR_RS05890	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PBPR_RS05895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PBPR_RS05900	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PBPR_RS05910	COG1301	dicarboxylic acid transport
PBPR_RS05915	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBPR_RS05915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBPR_RS05950	COG1295	ribonuclease BN
PBPR_RS05970	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PBPR_RS05980	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
PBPR_RS05985	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PBPR_RS05990	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PBPR_RS06000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PBPR_RS06005	COG0659	secondary active sulfate transmembrane transporter activity
PBPR_RS06010	COG1530	ribonuclease E activity
PBPR_RS06015	COG0564	pseudouridine synthase activity
PBPR_RS06025	COG0424	maF-like protein
PBPR_RS06030	COG1399	metal-binding, possibly nucleic acid-binding protein
PBPR_RS06035	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PBPR_RS06040	COG0416	fatty acid biosynthetic process
PBPR_RS06045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PBPR_RS06060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PBPR_RS06065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PBPR_RS06070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PBPR_RS06075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PBPR_RS06080	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PBPR_RS06085	COG0470	DNA polymerase III
PBPR_RS06090	COG0084	hydrolase, TatD family'
PBPR_RS06100	COG2431	L-lysine efflux transmembrane transporter activity
PBPR_RS06115	COG3070	regulator of competence-specific genes
PBPR_RS06120	COG0583	DNA-binding transcription factor activity
PBPR_RS06130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PBPR_RS06140	COG3852	Histidine kinase
PBPR_RS06140	COG3852	Histidine kinase
PBPR_RS06150	COG0517	IMP dehydrogenase activity
PBPR_RS06150	COG0617	tRNA 3'-terminal CCA addition
PBPR_RS06150	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PBPR_RS06160	COG0471	metal ion transport
PBPR_RS06165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PBPR_RS06165	COG4191	Histidine kinase
PBPR_RS06175	COG4467	Involved in initiation control of chromosome replication
PBPR_RS06180	COG2217	Heavy metal translocating P-type atpase
PBPR_RS06205	COG1263	PTS System
PBPR_RS06205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PBPR_RS06210	COG0366	Alpha amylase catalytic
PBPR_RS06215	COG1280	lysine exporter protein (LysE YggA)
PBPR_RS06220	COG1289	transmembrane transporter activity
PBPR_RS06225	COG0210	DNA helicase
PBPR_RS06235	COG1803	Methylglyoxal synthase
PBPR_RS06240	COG1879	ABC-type sugar transport system periplasmic component
PBPR_RS06245	COG2205	protein histidine kinase activity
PBPR_RS06245	COG2198	Histidine kinase
PBPR_RS06245	COG0784	Response regulator, receiver
PBPR_RS06255	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PBPR_RS06265	COG2501	S4 domain
PBPR_RS06280	COG4989	oxidoreductase activity
PBPR_RS06285	COG2897	thiosulfate sulfurtransferase activity
PBPR_RS06320	COG0372	Belongs to the citrate synthase family
PBPR_RS06340	COG1355	regulation of microtubule-based process
PBPR_RS06350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PBPR_RS06370	COG2258	MOSC domain
PBPR_RS06375	COG4235	cytochrome complex assembly
PBPR_RS06385	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
PBPR_RS06390	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
PBPR_RS06395	COG0437	4 iron, 4 sulfur cluster binding
PBPR_RS06400	COG3301	Polysulphide reductase, NrfD
PBPR_RS06405	COG1138	Cytochrome C-type biogenesis protein
PBPR_RS06415	COG3088	subunit of a heme lyase
PBPR_RS06415	COG4235	cytochrome complex assembly
PBPR_RS06420	COG2015	COG2015, Alkyl sulfatase and related hydrolases
PBPR_RS06425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PBPR_RS06430	COG4520	surface antigen
PBPR_RS06440	COG3525	Glycosyl hydrolase, family 20, catalytic domain
PBPR_RS06455	COG1737	Transcriptional regulator
PBPR_RS06460	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PBPR_RS06470	COG4145	pantothenate transmembrane transporter activity
PBPR_RS06475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PBPR_RS06480	COG0800	Aldolase
PBPR_RS06490	COG1115	amino acid carrier protein
PBPR_RS06525	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PBPR_RS06530	COG1984	allophanate hydrolase subunit 2
PBPR_RS06550	COG0318	PFAM AMP-dependent synthetase and ligase
PBPR_RS06580	COG0366	Alpha amylase catalytic
PBPR_RS06585	COG0494	nUDIX hydrolase
PBPR_RS06590	COG0247	lactate metabolic process
PBPR_RS06590	COG0277	FAD linked oxidase domain protein
PBPR_RS06595	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PBPR_RS06635	COG1032	radical SAM domain protein
PBPR_RS06640	COG0582	viral genome integration into host DNA
PBPR_RS06680	COG0305	Participates in initiation and elongation during chromosome replication
PBPR_RS06715	COG2433	Pfam Transposase IS66
PBPR_RS06810	COG4974	Belongs to the 'phage' integrase family
PBPR_RS06835	COG2433	Pfam Transposase IS66
PBPR_RS06845	COG3033	Beta-eliminating lyase
PBPR_RS06865	COG3969	phosphoadenosine phosphosulfate
PBPR_RS06870	COG1475	DNA binding
PBPR_RS06905	COG0740	serine-type endopeptidase activity
PBPR_RS06940	COG1280	lysine exporter protein (LysE YggA)
PBPR_RS06950	COG3335	DDE superfamily endonuclease
PBPR_RS06965	COG3069	C4-dicarboxylate transmembrane transporter activity
PBPR_RS06970	COG0583	DNA-binding transcription factor activity
PBPR_RS06985	COG0247	lactate metabolic process
PBPR_RS06990	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
PBPR_RS06995	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PBPR_RS07005	COG3335	DDE superfamily endonuclease
PBPR_RS07025	COG0583	DNA-binding transcription factor activity
PBPR_RS07030	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PBPR_RS07040	COG0668	transmembrane transport
PBPR_RS07075	COG4467	Involved in initiation control of chromosome replication
PBPR_RS07100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PBPR_RS07105	COG0581	inorganic phosphate transmembrane transporter activity
PBPR_RS07110	COG0573	inorganic phosphate transmembrane transporter activity
PBPR_RS07125	COG0583	DNA-binding transcription factor activity
PBPR_RS07130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PBPR_RS07155	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PBPR_RS07165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PBPR_RS07190	COG1139	Iron-sulfur cluster binding protein
PBPR_RS07200	COG1620	l-lactate permease
PBPR_RS07205	COG0583	DNA-binding transcription factor activity
PBPR_RS07270	COG2116	formate transmembrane transporter activity
PBPR_RS07280	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PBPR_RS07305	COG0814	amino acid
PBPR_RS07320	COG1388	LysM domain
PBPR_RS07320	COG0791	NLP P60 protein
PBPR_RS07330	COG1653	transport
PBPR_RS07335	COG2199	diguanylate cyclase activity
PBPR_RS07345	COG0653	protein targeting
PBPR_RS07350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PBPR_RS07355	COG0363	glucosamine-6-phosphate deaminase activity
PBPR_RS07360	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PBPR_RS07365	COG1115	amino acid carrier protein
PBPR_RS07420	COG2070	2-Nitropropane dioxygenase
PBPR_RS07420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PBPR_RS07435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PBPR_RS07435	COG3321	synthase
PBPR_RS07450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PBPR_RS07455	COG0596	Alpha beta hydrolase
PBPR_RS07460	COG0318	PFAM AMP-dependent synthetase and ligase
PBPR_RS07465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBPR_RS07480	COG3005	denitrification pathway
PBPR_RS07490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PBPR_RS07505	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PBPR_RS07520	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PBPR_RS07525	COG0765	amino acid transport
PBPR_RS07530	COG1126	abc transporter atp-binding protein
PBPR_RS07540	COG1301	dicarboxylic acid transport
PBPR_RS07545	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PBPR_RS07550	COG0531	amino acid
PBPR_RS07560	COG0443	Heat shock 70 kDa protein
PBPR_RS07590	COG4467	Involved in initiation control of chromosome replication
PBPR_RS07605	COG3381	protein complex oligomerization
PBPR_RS07615	COG3005	denitrification pathway
PBPR_RS07620	COG0745	RESPONSE REGULATOR receiver
PBPR_RS07625	COG0076	glutamate decarboxylase activity
PBPR_RS07690	COG0733	neurotransmitter:sodium symporter activity
PBPR_RS07705	COG4667	esterase of the alpha-beta hydrolase superfamily
PBPR_RS07710	COG1227	inorganic diphosphatase activity
PBPR_RS07740	COG2814	Major facilitator Superfamily
PBPR_RS07745	COG3099	Belongs to the UPF0263 family
PBPR_RS07750	COG2200	EAL domain
PBPR_RS07765	COG1901	pseudouridine methyltransferase
PBPR_RS07790	COG0417	DNA replication proofreading
PBPR_RS07800	COG3313	Fe-S protein
PBPR_RS07805	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PBPR_RS07810	COG4771	TonB-dependent receptor
PBPR_RS07815	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PBPR_RS07825	COG3335	DDE superfamily endonuclease
PBPR_RS07830	COG1061	Type III restriction enzyme res subunit
PBPR_RS07835	COG0798	PFAM Bile acid sodium symporter
PBPR_RS07860	COG2814	Major facilitator Superfamily
PBPR_RS07885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PBPR_RS07890	COG0702	epimerase
PBPR_RS07895	COG0534	Mate efflux family protein
PBPR_RS07915	COG1473	amidohydrolase
PBPR_RS07925	COG1538	Outer membrane efflux protein
PBPR_RS07935	COG1566	PFAM secretion protein HlyD family protein
PBPR_RS07945	COG0628	permease
PBPR_RS07960	COG1120	ATPase activity
PBPR_RS07965	COG4774	siderophore transport
PBPR_RS07970	COG1132	(ABC) transporter
PBPR_RS07980	COG4467	Involved in initiation control of chromosome replication
PBPR_RS07995	COG3596	GTP binding
PBPR_RS08000	COG1609	Transcriptional regulator
PBPR_RS08010	COG1105	Belongs to the carbohydrate kinase PfkB family
PBPR_RS08015	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PBPR_RS08015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PBPR_RS08015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PBPR_RS08025	COG0531	amino acid
PBPR_RS08075	COG5433	transposase activity
PBPR_RS08085	COG2433	Pfam Transposase IS66
PBPR_RS08125	COG1201	RNA secondary structure unwinding
PBPR_RS08165	COG0535	radical SAM domain protein
PBPR_RS08185	COG2433	Pfam Transposase IS66
PBPR_RS08195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PBPR_RS08215	COG0561	phosphatase activity
PBPR_RS08270	COG5433	transposase activity
PBPR_RS08280	COG3344	reverse transcriptase
PBPR_RS08300	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBPR_RS08300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBPR_RS08350	COG0653	protein targeting
PBPR_RS08370	COG1757	Na H antiporter
PBPR_RS08375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PBPR_RS08420	COG0488	(ABC) transporter
PBPR_RS08435	COG1288	antiporter activity
PBPR_RS08440	COG1132	(ABC) transporter
PBPR_RS08445	COG1132	(ABC) transporter
PBPR_RS08450	COG1021	2,3-dihydroxybenzoate-AMP ligase
PBPR_RS08455	COG1169	isochorismate synthase
PBPR_RS08480	COG2226	methyltransferase
PBPR_RS08480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PBPR_RS08480	COG3433	isochorismatase activity
PBPR_RS08485	COG2814	Major facilitator Superfamily
PBPR_RS08490	COG4771	TonB-dependent receptor
PBPR_RS08560	COG0500	methyltransferase
PBPR_RS08565	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PBPR_RS08580	COG0697	spore germination
PBPR_RS08585	COG0295	cytidine deaminase activity
PBPR_RS08590	COG1346	cytolysis
PBPR_RS08595	COG1380	Effector of murein hydrolase LrgA
PBPR_RS08605	COG2925	Exonuclease
PBPR_RS08640	COG4467	Involved in initiation control of chromosome replication
PBPR_RS08650	COG3335	DDE superfamily endonuclease
PBPR_RS08660	COG2801	Transposase and inactivated derivatives
PBPR_RS08675	COG1643	Atp-dependent helicase
PBPR_RS08700	COG3335	DDE superfamily endonuclease
PBPR_RS08720	COG2194	sulfuric ester hydrolase activity
PBPR_RS08745	COG1215	transferase activity, transferring glycosyl groups
PBPR_RS08750	COG1215	transferase activity, transferring glycosyl groups
PBPR_RS08755	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
PBPR_RS08760	COG0457	Tetratricopeptide repeat
PBPR_RS08770	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PBPR_RS08775	COG0366	Alpha amylase catalytic
PBPR_RS08790	COG0156	8-amino-7-oxononanoate synthase activity
PBPR_RS08795	COG1063	alcohol dehydrogenase
PBPR_RS08810	COG0438	transferase activity, transferring glycosyl groups
PBPR_RS08815	COG0463	Glycosyl transferase, family 2
PBPR_RS08815	COG1216	Glycosyl transferase, family 2
PBPR_RS08830	COG0488	(ABC) transporter
PBPR_RS08835	COG1671	Belongs to the UPF0178 family
PBPR_RS08860	COG2201	protein-glutamate methylesterase activity
PBPR_RS08865	COG3706	GGDEF domain
PBPR_RS08875	COG3148	PFAM DTW domain containing protein
PBPR_RS08880	COG1940	carbohydrate kinase activity
PBPR_RS08885	COG0513	Belongs to the DEAD box helicase family
PBPR_RS08895	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PBPR_RS08900	COG0574	Belongs to the PEP-utilizing enzyme family
PBPR_RS08900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PBPR_RS08910	COG2207	Transcriptional regulator
PBPR_RS08920	COG4467	Involved in initiation control of chromosome replication
PBPR_RS08925	COG0534	Mate efflux family protein
PBPR_RS08930	COG1643	Atp-dependent helicase
PBPR_RS08935	COG0826	peptidase U32
PBPR_RS08950	COG1263	PTS System
PBPR_RS08950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PBPR_RS08960	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PBPR_RS08965	COG0308	aminopeptidase N
PBPR_RS08970	COG2902	Dehydrogenase
PBPR_RS08975	COG0167	dihydroorotate dehydrogenase activity
PBPR_RS08985	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PBPR_RS08985	COG0116	Belongs to the methyltransferase superfamily
PBPR_RS08995	COG0488	(ABC) transporter
PBPR_RS09010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PBPR_RS09015	COG1067	ATP-dependent peptidase activity
PBPR_RS09020	COG3120	sequence-specific DNA binding
PBPR_RS09030	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PBPR_RS09050	COG3710	Transcriptional regulator
PBPR_RS09100	COG1162	GTPase activity
PBPR_RS09140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PBPR_RS09235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PBPR_RS09250	COG4467	Involved in initiation control of chromosome replication
PBPR_RS09285	COG0784	Response regulator, receiver
PBPR_RS09285	COG5002	protein histidine kinase activity
PBPR_RS09305	COG3278	Belongs to the heme-copper respiratory oxidase family
PBPR_RS09320	COG2010	Cytochrome c
PBPR_RS09330	COG2217	Heavy metal translocating P-type atpase
PBPR_RS09345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PBPR_RS09350	COG0589	response to stress
PBPR_RS09360	COG0037	tRNA processing
PBPR_RS09365	COG1686	Belongs to the peptidase S11 family
PBPR_RS09370	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PBPR_RS09380	COG5654	RES domain protein
PBPR_RS09385	COG5642	Protein of unknown function (DUF2384)
PBPR_RS09395	COG2195	Cleaves the N-terminal amino acid of tripeptides
PBPR_RS09415	COG3842	ATPase activity
PBPR_RS09425	COG1177	transmembrane transport
PBPR_RS09435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PBPR_RS09445	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PBPR_RS09455	COG0437	4 iron, 4 sulfur cluster binding
PBPR_RS09460	COG3383	formate dehydrogenase (NAD+) activity
PBPR_RS09470	COG3381	protein complex oligomerization
PBPR_RS09490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PBPR_RS09500	COG4221	oxidoreductase activity
PBPR_RS09520	COG2315	Protein conserved in bacteria
PBPR_RS09525	COG1686	Belongs to the peptidase S11 family
PBPR_RS09530	COG0328	RNA-DNA hybrid ribonuclease activity
PBPR_RS09530	COG3341	Caulimovirus viroplasmin
PBPR_RS09565	COG0741	lytic transglycosylase activity
PBPR_RS09565	COG1388	LysM domain
PBPR_RS09575	COG4467	Involved in initiation control of chromosome replication
PBPR_RS09580	COG0477	Major facilitator Superfamily
PBPR_RS09585	COG3852	Histidine kinase
PBPR_RS09600	COG4662	Binding-protein-dependent transport system inner membrane component
PBPR_RS09605	COG3842	ATPase activity
PBPR_RS09610	COG0746	molybdenum cofactor guanylyltransferase activity
PBPR_RS09635	COG4948	Mandelate Racemase Muconate Lactonizing
PBPR_RS09655	COG0671	phosphoesterase, PA-phosphatase related
PBPR_RS09685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PBPR_RS09690	COG1278	Cold shock
PBPR_RS09695	COG0784	Response regulator, receiver
PBPR_RS09695	COG0835	chemotaxis
PBPR_RS09710	COG1418	mRNA catabolic process
PBPR_RS09715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PBPR_RS09730	COG0346	lactoylglutathione lyase activity
PBPR_RS09750	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
PBPR_RS09755	COG1956	GAF domain-containing protein
PBPR_RS09760	COG1132	(ABC) transporter
PBPR_RS09765	COG2995	paraquat-inducible protein a
PBPR_RS09770	COG3008	intermembrane lipid transfer
PBPR_RS09775	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
PBPR_RS09775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PBPR_RS09785	COG2252	PERMEase
PBPR_RS09790	COG0402	S-adenosylhomocysteine deaminase activity
PBPR_RS09800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PBPR_RS09800	COG2080	2 iron, 2 sulfur cluster binding
PBPR_RS09805	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PBPR_RS09810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PBPR_RS09820	COG0488	(ABC) transporter
PBPR_RS09825	COG4467	Involved in initiation control of chromosome replication
PBPR_RS09830	COG4221	oxidoreductase activity
PBPR_RS09835	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PBPR_RS09850	COG0402	S-adenosylhomocysteine deaminase activity
PBPR_RS09855	COG0493	'glutamate synthase
PBPR_RS09855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PBPR_RS09915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBPR_RS09915	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBPR_RS09930	COG4467	Involved in initiation control of chromosome replication
PBPR_RS09940	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PBPR_RS09955	COG2926	Belongs to the UPF0265 family
PBPR_RS09960	COG1278	Cold shock
PBPR_RS09965	COG1278	Cold shock
PBPR_RS09970	COG1181	Belongs to the D-alanine--D-alanine ligase family
PBPR_RS10000	COG3706	GGDEF domain
PBPR_RS10020	COG4467	Involved in initiation control of chromosome replication
PBPR_RS10035	COG0789	Transcriptional regulator
PBPR_RS10080	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PBPR_RS10080	COG3608	succinylglutamate desuccinylase aspartoacylase
PBPR_RS10085	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PBPR_RS10090	COG2068	MobA-Related Protein
PBPR_RS10095	COG1013	pyruvate-flavodoxin oxidoreductase activity
PBPR_RS10095	COG0674	pyruvate-flavodoxin oxidoreductase activity
PBPR_RS10095	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PBPR_RS10095	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PBPR_RS10100	COG0493	'glutamate synthase
PBPR_RS10105	COG0549	Belongs to the carbamate kinase family
PBPR_RS10115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PBPR_RS10120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PBPR_RS10125	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PBPR_RS10130	COG3829	transcription factor binding
PBPR_RS10135	COG0281	malic enzyme
PBPR_RS10140	COG2949	membrane
PBPR_RS10145	COG0471	metal ion transport
PBPR_RS10150	COG0673	inositol 2-dehydrogenase activity
PBPR_RS10155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PBPR_RS10160	COG0861	Integral membrane protein TerC family
PBPR_RS10170	COG2989	Protein conserved in bacteria
PBPR_RS10180	COG1328	CTP reductase activity
PBPR_RS10185	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PBPR_RS10190	COG0583	DNA-binding transcription factor activity
PBPR_RS10195	COG0302	gtp cyclohydrolase
PBPR_RS10210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PBPR_RS10220	COG4166	transmembrane transport
PBPR_RS10240	COG0840	transmembrane signaling receptor activity
PBPR_RS10250	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PBPR_RS10265	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PBPR_RS10270	COG1666	GTP binding
PBPR_RS10280	COG1741	Belongs to the pirin family
PBPR_RS10285	COG1560	Kdo2-lipid A biosynthetic process
PBPR_RS10290	COG3005	denitrification pathway
PBPR_RS10295	COG3043	anaerobic respiration
PBPR_RS10300	COG0243	molybdopterin cofactor binding
PBPR_RS10345	COG1131	(ABC) transporter
PBPR_RS10350	COG2188	Transcriptional regulator
PBPR_RS10380	COG2801	Transposase and inactivated derivatives
PBPR_RS10395	COG1115	amino acid carrier protein
PBPR_RS10415	COG1280	lysine exporter protein (LysE YggA)
PBPR_RS10430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PBPR_RS10460	COG0242	peptide deformylase activity
PBPR_RS10465	COG1957	nucleoside hydrolase
PBPR_RS10490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PBPR_RS10520	COG1126	abc transporter atp-binding protein
PBPR_RS10525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PBPR_RS10530	COG4215	(ABC) transporter
PBPR_RS10535	COG4160	amino acid transport
PBPR_RS10550	COG2017	converts alpha-aldose to the beta-anomer
PBPR_RS10565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PBPR_RS10570	COG1609	Transcriptional regulator
PBPR_RS10575	COG3250	beta-galactosidase activity
PBPR_RS10580	COG2731	YhcH YjgK YiaL family protein
PBPR_RS10585	COG0531	amino acid
PBPR_RS10600	COG0786	glutamate:sodium symporter activity
PBPR_RS10610	COG1192	Involved in chromosome partitioning
PBPR_RS10645	COG2801	Transposase and inactivated derivatives
PBPR_RS10655	COG0748	coenzyme F420 binding
PBPR_RS10660	COG3721	Heme iron utilization protein
PBPR_RS10670	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PBPR_RS10675	COG0811	peptide transport
PBPR_RS10680	COG0848	biopolymer transport protein
PBPR_RS10690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBPR_RS10695	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PBPR_RS10700	COG1609	Transcriptional regulator
PBPR_RS10705	COG3070	regulator of competence-specific genes
PBPR_RS10715	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PBPR_RS10725	COG4134	Bacterial extracellular solute-binding protein
PBPR_RS10730	COG4135	transport system, permease component
PBPR_RS10735	COG4136	ATPase activity
PBPR_RS10740	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PBPR_RS10750	COG0583	DNA-binding transcription factor activity
PBPR_RS10755	COG0583	DNA-binding transcription factor activity
PBPR_RS10760	COG2814	Major facilitator Superfamily
PBPR_RS10805	COG0484	heat shock protein binding
PBPR_RS10815	COG1115	amino acid carrier protein
PBPR_RS10835	COG0443	Heat shock 70 kDa protein
PBPR_RS10845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PBPR_RS10860	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PBPR_RS10870	COG2985	domain, Protein
PBPR_RS10880	COG1609	Transcriptional regulator
PBPR_RS10885	COG1757	Na H antiporter
PBPR_RS10890	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PBPR_RS10895	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PBPR_RS10895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PBPR_RS10905	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
PBPR_RS10910	COG4139	cobalamin transport
PBPR_RS10915	COG2988	succinylglutamate desuccinylase activity
PBPR_RS10920	COG0776	regulation of translation
PBPR_RS10925	COG0072	phenylalanine-tRNA ligase activity
PBPR_RS10925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBPR_RS10930	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PBPR_RS10935	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PBPR_RS10945	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PBPR_RS10990	COG3097	Belongs to the UPF0267 family
PBPR_RS11000	COG1228	amidohydrolase
PBPR_RS11005	COG0010	Belongs to the arginase family
PBPR_RS11010	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PBPR_RS11015	COG2986	histidine ammonia-lyase
PBPR_RS11020	COG3001	Fructosamine kinase
PBPR_RS11025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PBPR_RS11035	COG0307	riboflavin synthase, alpha
PBPR_RS11060	COG0534	Mate efflux family protein
PBPR_RS11070	COG1858	cytochrome C peroxidase
PBPR_RS11085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PBPR_RS11090	COG4597	amino acid ABC transporter
PBPR_RS11095	COG0765	amino acid transport
PBPR_RS11100	COG1126	abc transporter atp-binding protein
PBPR_RS11105	COG0670	Belongs to the BI1 family
PBPR_RS11110	COG2920	part of a sulfur-relay system
PBPR_RS11115	COG1254	Belongs to the acylphosphatase family
PBPR_RS11120	COG0840	transmembrane signaling receptor activity
PBPR_RS11125	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PBPR_RS11135	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
PBPR_RS11155	COG0686	Belongs to the AlaDH PNT family
PBPR_RS11160	COG1213	nucleotidyl transferase
PBPR_RS11170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PBPR_RS11185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PBPR_RS11195	COG0640	Transcriptional regulator
PBPR_RS11210	COG4221	oxidoreductase activity
PBPR_RS11265	COG0583	DNA-binding transcription factor activity
PBPR_RS11270	COG1620	l-lactate permease
PBPR_RS11275	COG0277	FAD linked oxidase domain protein
PBPR_RS11345	COG0322	excinuclease ABC activity
PBPR_RS11350	COG2197	response regulator
PBPR_RS11355	COG4720	Psort location CytoplasmicMembrane, score
PBPR_RS11360	COG1122	ATPase activity
PBPR_RS11380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PBPR_RS11390	COG0402	S-adenosylhomocysteine deaminase activity
PBPR_RS11405	COG0789	Transcriptional regulator
PBPR_RS11440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PBPR_RS11455	COG4580	involved in the transport of maltose and maltodextrins
PBPR_RS11485	COG4266	Belongs to the allantoicase family
PBPR_RS11505	COG2252	PERMEase
PBPR_RS11525	COG4667	esterase of the alpha-beta hydrolase superfamily
PBPR_RS11545	COG2084	Dehydrogenase
PBPR_RS11550	COG3622	Belongs to the hyi family
PBPR_RS11555	COG3960	tartronate-semialdehyde synthase activity
PBPR_RS11560	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PBPR_RS11575	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PBPR_RS11580	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PBPR_RS11585	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PBPR_RS11590	COG2731	YhcH YjgK YiaL family protein
PBPR_RS11595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBPR_RS11605	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PBPR_RS11610	COG1737	Transcriptional regulator
PBPR_RS11615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PBPR_RS11630	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
PBPR_RS11645	COG2301	Belongs to the HpcH HpaI aldolase family
PBPR_RS11665	COG3630	sodium ion export across plasma membrane
PBPR_RS11670	COG0511	ligase activity, forming carbon-carbon bonds
PBPR_RS11670	COG5016	pyruvate
PBPR_RS11675	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
PBPR_RS11685	COG4565	transcriptional regulatory protein
PBPR_RS11695	COG0840	transmembrane signaling receptor activity
PBPR_RS11720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PBPR_RS11735	COG0842	Transport permease protein
PBPR_RS11740	COG1131	(ABC) transporter
PBPR_RS11745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBPR_RS11750	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PBPR_RS11765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PBPR_RS11770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBPR_RS11785	COG0501	Belongs to the peptidase M48B family
PBPR_RS11810	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PBPR_RS11815	COG2226	methyltransferase
PBPR_RS11820	COG0156	8-amino-7-oxononanoate synthase activity
PBPR_RS11825	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PBPR_RS11830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PBPR_RS11840	COG1940	carbohydrate kinase activity
PBPR_RS11845	COG0602	queuosine metabolic process
PBPR_RS11855	COG0017	Asparaginyl-tRNA synthetase
PBPR_RS11865	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PBPR_RS11870	COG0352	thiamine-phosphate diphosphorylase activity
PBPR_RS11875	COG4807	Protein conserved in bacteria
PBPR_RS11880	COG1024	Enoyl-CoA hydratase
PBPR_RS11890	COG1448	Aminotransferase
PBPR_RS11910	COG2271	Major facilitator Superfamily
PBPR_RS11920	COG2197	response regulator
PBPR_RS11930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PBPR_RS11935	COG3108	Peptidase M15
PBPR_RS11940	COG2989	Protein conserved in bacteria
PBPR_RS11950	COG0583	DNA-binding transcription factor activity
PBPR_RS11955	COG0730	response to heat
PBPR_RS11960	COG0583	DNA-binding transcription factor activity
PBPR_RS11970	COG1620	l-lactate permease
PBPR_RS11975	COG0247	lactate metabolic process
PBPR_RS11980	COG1139	Iron-sulfur cluster binding protein
PBPR_RS11985	COG1556	Lactate utilization protein
PBPR_RS11990	COG0583	DNA-binding transcription factor activity
PBPR_RS12000	COG0243	molybdopterin cofactor binding
PBPR_RS12005	COG3005	denitrification pathway
PBPR_RS12010	COG4459	periplasmic nitrate reductase
PBPR_RS12015	COG0739	heme binding
PBPR_RS12060	COG2801	Transposase and inactivated derivatives
PBPR_RS12070	COG3335	DDE superfamily endonuclease
PBPR_RS12085	COG2433	Pfam Transposase IS66
PBPR_RS12095	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
PBPR_RS12100	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
PBPR_RS12105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PBPR_RS12110	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PBPR_RS12120	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PBPR_RS12125	COG2835	tetraacyldisaccharide 4'-kinase activity
PBPR_RS12130	COG1663	tetraacyldisaccharide 4'-kinase activity
PBPR_RS12135	COG1132	(ABC) transporter
PBPR_RS12140	COG0658	competence protein
PBPR_RS12140	COG2333	competence protein COMEC
PBPR_RS12150	COG4591	ABC-type transport system involved in lipoprotein release permease component
PBPR_RS12155	COG1136	(ABC) transporter
PBPR_RS12160	COG4591	ABC-type transport system involved in lipoprotein release permease component
PBPR_RS12170	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PBPR_RS12185	COG0545	Peptidyl-prolyl cis-trans isomerase
PBPR_RS12190	COG1252	NADH dehydrogenase
PBPR_RS12195	COG3150	esterase
PBPR_RS12225	COG0537	adenosine 5'-monophosphoramidase activity
PBPR_RS12235	COG0418	dihydroorotase activity
PBPR_RS12260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PBPR_RS12270	COG0814	amino acid
PBPR_RS12275	COG1760	l-serine dehydratase
PBPR_RS12285	COG1584	GPR1 FUN34 yaaH family protein
PBPR_RS12295	COG0778	Nitroreductase
PBPR_RS12310	COG2985	domain, Protein
PBPR_RS12310	COG0569	domain protein
PBPR_RS12325	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PBPR_RS12330	COG1960	acyl-CoA dehydrogenase activity
PBPR_RS12355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBPR_RS12360	COG1737	Transcriptional regulator
PBPR_RS12365	COG0469	pyruvate kinase activity
PBPR_RS12370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PBPR_RS12375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PBPR_RS12385	COG3768	UPF0283 membrane protein
PBPR_RS12390	COG3106	COG3106 Predicted ATPase
PBPR_RS12405	COG1842	Phage shock protein A
PBPR_RS12410	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PBPR_RS12420	COG4168	peptide transport system, permease
PBPR_RS12435	COG4172	Belongs to the ABC transporter superfamily
PBPR_RS12440	COG0284	orotidine-5'-phosphate decarboxylase activity
PBPR_RS12445	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PBPR_RS12450	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
PBPR_RS12455	COG0776	regulation of translation
PBPR_RS12460	COG0539	negative regulation of cytoplasmic translation
PBPR_RS12465	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PBPR_RS12470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PBPR_RS12475	COG0494	nUDIX hydrolase
PBPR_RS12485	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PBPR_RS12500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PBPR_RS12510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PBPR_RS12520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PBPR_RS12530	COG1058	Belongs to the CinA family
PBPR_RS12530	COG1546	Belongs to the CinA family
PBPR_RS12535	COG0814	amino acid
PBPR_RS12545	COG5001	Diguanylate cyclase
PBPR_RS12560	COG0583	DNA-binding transcription factor activity
PBPR_RS12595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PBPR_RS12605	COG3152	Membrane
PBPR_RS12610	COG0616	signal peptide processing
PBPR_RS12615	COG1028	Short-chain dehydrogenase reductase Sdr
PBPR_RS12625	COG0009	L-threonylcarbamoyladenylate synthase
PBPR_RS12630	COG0613	PHP domain protein
PBPR_RS12635	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PBPR_RS12640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PBPR_RS12645	COG0512	Glutamine amidotransferase of anthranilate synthase
PBPR_RS12650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PBPR_RS12655	COG0134	indole-3-glycerol-phosphate synthase activity
PBPR_RS12655	COG0135	phosphoribosylanthranilate isomerase activity
PBPR_RS12660	COG0133	tryptophan synthase activity
PBPR_RS12665	COG0159	tryptophan synthase activity
PBPR_RS12670	COG1301	dicarboxylic acid transport
PBPR_RS12675	COG0583	DNA-binding transcription factor activity
PBPR_RS12695	COG4964	Belongs to the GSP D family
PBPR_RS12705	COG0455	bacterial-type flagellum organization
PBPR_RS12750	COG2917	probably involved in intracellular septation
PBPR_RS12755	COG1607	acyl-coa hydrolase
PBPR_RS12760	COG2350	Protein conserved in bacteria
PBPR_RS12770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PBPR_RS12770	COG0116	Belongs to the methyltransferase superfamily
PBPR_RS12775	COG0564	pseudouridine synthase activity
PBPR_RS12780	COG0733	neurotransmitter:sodium symporter activity
PBPR_RS12795	COG5001	Diguanylate cyclase
PBPR_RS12795	COG3300	MHYT domain
PBPR_RS12800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PBPR_RS12815	COG1454	alcohol dehydrogenase
PBPR_RS12820	COG2815	serine threonine protein kinase
PBPR_RS12820	COG0515	serine threonine protein kinase
PBPR_RS12825	COG2223	nitrite transmembrane transporter activity
PBPR_RS12830	COG2146	nitrite reductase [NAD(P)H] activity
PBPR_RS12835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PBPR_RS12840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PBPR_RS12840	COG1648	precorrin-2 dehydrogenase activity
PBPR_RS12845	COG0243	molybdopterin cofactor binding
PBPR_RS12850	COG0657	acetylesterase activity
PBPR_RS12855	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PBPR_RS12880	COG3264	Mechanosensitive ion channel
PBPR_RS12880	COG1511	domain protein
PBPR_RS12885	COG3033	Beta-eliminating lyase
PBPR_RS12890	COG0814	amino acid
PBPR_RS12895	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
PBPR_RS12960	COG0385	Bile acid
PBPR_RS12965	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PBPR_RS12970	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PBPR_RS12975	COG2885	chlorophyll binding
PBPR_RS12980	COG0823	Involved in the tonB-independent uptake of proteins
PBPR_RS12990	COG0848	biopolymer transport protein
PBPR_RS12995	COG0811	peptide transport
PBPR_RS13000	COG0824	Thioesterase
PBPR_RS13015	COG1294	oxidase, subunit
PBPR_RS13020	COG1271	oxidase subunit
PBPR_RS13030	COG4657	Part of a membrane complex involved in electron transport
PBPR_RS13040	COG4656	Part of a membrane complex involved in electron transport
PBPR_RS13045	COG4658	electron transport chain
PBPR_RS13050	COG4659	FMN binding
PBPR_RS13055	COG4660	Part of a membrane complex involved in electron transport
PBPR_RS13060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PBPR_RS13065	COG0346	lactoylglutathione lyase activity
PBPR_RS13090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PBPR_RS13095	COG2067	long-chain fatty acid transport protein
PBPR_RS13100	COG2267	carboxylic ester hydrolase activity
PBPR_RS13105	COG0450	alkyl hydroperoxide reductase
PBPR_RS13110	COG2056	Na+-H+ antiporter family
PBPR_RS13115	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PBPR_RS13125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PBPR_RS13130	COG1757	Na H antiporter
PBPR_RS13135	COG3366	ferrous iron transmembrane transporter activity
PBPR_RS13140	COG0700	Nucleoside recognition
PBPR_RS13145	COG2195	Cleaves the N-terminal amino acid of tripeptides
PBPR_RS13155	COG3081	Nucleoid-associated protein
PBPR_RS13160	COG3082	Protein of unknown function (DUF1414)
PBPR_RS13175	COG2203	Gaf domain
PBPR_RS13175	COG3706	GGDEF domain
PBPR_RS13175	COG4251	negative regulation of phosphorylation
PBPR_RS13175	COG5001	Diguanylate cyclase
PBPR_RS13180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PBPR_RS13185	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PBPR_RS13190	COG0709	Synthesizes selenophosphate from selenide and ATP
PBPR_RS13195	COG0778	Nitroreductase
PBPR_RS13200	COG0446	pyridine nucleotide-disulphide oxidoreductase
PBPR_RS13200	COG1902	pentaerythritol trinitrate reductase activity
PBPR_RS13205	COG0616	signal peptide processing
PBPR_RS13210	COG0252	asparaginase activity
PBPR_RS13220	COG3139	Protein of unknown function (DUF1315)
PBPR_RS13235	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PBPR_RS13240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PBPR_RS13245	COG0676	glucose-6-phosphate 1-epimerase activity
PBPR_RS13255	COG2766	serine protein kinase
PBPR_RS13260	COG2718	Belongs to the UPF0229 family
PBPR_RS13265	COG2719	SpoVR family
PBPR_RS13270	COG2186	Transcriptional regulator
PBPR_RS13275	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PBPR_RS13280	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PBPR_RS13295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PBPR_RS13300	COG2983	Belongs to the UPF0260 family
PBPR_RS13330	COG0477	Major facilitator Superfamily
PBPR_RS13340	COG1441	menaquinone biosynthetic process
PBPR_RS13350	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PBPR_RS13355	COG1169	isochorismate synthase
PBPR_RS13360	COG0436	Aminotransferase
PBPR_RS13365	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
PBPR_RS13395	COG1555	photosystem II stabilization
PBPR_RS13400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PBPR_RS13405	COG0776	regulation of translation
PBPR_RS13410	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PBPR_RS13415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PBPR_RS13420	COG0740	serine-type endopeptidase activity
PBPR_RS13425	COG0544	peptidyl-prolyl cis-trans isomerase activity
PBPR_RS13440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PBPR_RS13445	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PBPR_RS13455	COG3104	oligopeptide transport
PBPR_RS13460	COG0745	RESPONSE REGULATOR receiver
PBPR_RS13465	COG0583	DNA-binding transcription factor activity
PBPR_RS13475	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PBPR_RS13480	COG1286	toxin biosynthetic process
PBPR_RS13485	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
PBPR_RS13490	COG0285	dihydrofolate synthase activity
PBPR_RS13495	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PBPR_RS13500	COG0101	tRNA pseudouridine synthase activity
PBPR_RS13510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PBPR_RS13515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PBPR_RS13525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PBPR_RS13530	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PBPR_RS13530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PBPR_RS13540	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PBPR_RS13545	COG4467	Involved in initiation control of chromosome replication
PBPR_RS13550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PBPR_RS13565	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PBPR_RS13590	COG2336	PFAM SpoVT AbrB
PBPR_RS13595	COG2337	Toxic component of a toxin-antitoxin (TA) module
PBPR_RS13600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PBPR_RS13605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PBPR_RS13610	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PBPR_RS13625	COG0438	transferase activity, transferring glycosyl groups
PBPR_RS13665	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PBPR_RS13700	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PBPR_RS13720	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PBPR_RS13755	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PBPR_RS13760	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PBPR_RS13780	COG2089	acid synthase
PBPR_RS13790	COG1083	cytidylyl-transferase
PBPR_RS13795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PBPR_RS13800	COG1086	Polysaccharide biosynthesis protein
PBPR_RS13805	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PBPR_RS13810	COG2860	membrane
PBPR_RS13815	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PBPR_RS13820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PBPR_RS13820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PBPR_RS13820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PBPR_RS13830	COG2207	Transcriptional regulator
PBPR_RS13840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PBPR_RS13840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PBPR_RS13840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PBPR_RS13845	COG1187	pseudouridine synthase activity
PBPR_RS13850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PBPR_RS13895	COG0435	Glutathione S-transferase
PBPR_RS13900	COG3457	Alanine racemase
PBPR_RS13925	COG1757	Na H antiporter
PBPR_RS13930	COG0708	Exodeoxyribonuclease III
PBPR_RS13935	COG2999	glutathione oxidoreductase activity
PBPR_RS13940	COG4160	amino acid transport
PBPR_RS13945	COG4215	(ABC) transporter
PBPR_RS13970	COG1288	antiporter activity
PBPR_RS13975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PBPR_RS13985	COG1944	ATP diphosphatase activity
PBPR_RS13995	COG1882	Formate acetyltransferase
PBPR_RS14005	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PBPR_RS14045	COG1979	alcohol dehydrogenase
PBPR_RS14055	COG0583	DNA-binding transcription factor activity
PBPR_RS14060	COG4565	transcriptional regulatory protein
PBPR_RS14065	COG3290	protein histidine kinase activity
PBPR_RS14070	COG2759	Belongs to the formate--tetrahydrofolate ligase family
PBPR_RS14075	COG0583	DNA-binding transcription factor activity
PBPR_RS14080	COG2116	formate transmembrane transporter activity
PBPR_RS14090	COG3013	Belongs to the UPF0304 family
PBPR_RS14120	COG1735	metal-dependent hydrolase with the TIM-barrel fold
PBPR_RS14125	COG2188	Transcriptional regulator
PBPR_RS14135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PBPR_RS14140	COG1447	Phosphotransferase system cellobiose-specific component IIA
PBPR_RS14160	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PBPR_RS14165	COG3457	Alanine racemase
PBPR_RS14180	COG1735	metal-dependent hydrolase with the TIM-barrel fold
PBPR_RS14190	COG2188	Transcriptional regulator
PBPR_RS14195	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
PBPR_RS14200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PBPR_RS14205	COG2226	methyltransferase
PBPR_RS14220	COG4120	Belongs to the binding-protein-dependent transport system permease family
PBPR_RS14235	COG3092	negative regulation of chromosome organization
PBPR_RS14240	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PBPR_RS14245	COG0857	belongs to the CobB CobQ family
PBPR_RS14245	COG0280	phosphate acetyltransferase
PBPR_RS14275	COG4467	Involved in initiation control of chromosome replication
PBPR_RS14280	COG2116	formate transmembrane transporter activity
PBPR_RS14285	COG0622	Phosphoesterase
PBPR_RS14310	COG1090	epimerase
PBPR_RS14315	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PBPR_RS14320	COG4181	ATPase activity
PBPR_RS14335	COG0300	oxidoreductase activity
PBPR_RS14340	COG3118	belongs to the thioredoxin family
PBPR_RS14355	COG3710	Transcriptional regulator
PBPR_RS14370	COG2217	Heavy metal translocating P-type atpase
PBPR_RS14410	COG2840	Smr protein MutS2
PBPR_RS14420	COG0583	DNA-binding transcription factor activity
PBPR_RS14425	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PBPR_RS14445	COG0840	transmembrane signaling receptor activity
PBPR_RS14450	COG0814	amino acid
PBPR_RS14455	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PBPR_RS14460	COG2912	Transglutaminase-like superfamily
PBPR_RS14470	COG2890	protein-(glutamine-N5) methyltransferase activity
PBPR_RS14475	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PBPR_RS14480	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PBPR_RS14485	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PBPR_RS14490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PBPR_RS14495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PBPR_RS14500	COG0193	aminoacyl-tRNA hydrolase activity
PBPR_RS14630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PBPR_RS14635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PBPR_RS14640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PBPR_RS14645	COG1702	phosphate starvation-inducible protein PhoH
PBPR_RS14650	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PBPR_RS14655	COG4535	Mg2 and Co2 transporter CorC
PBPR_RS14660	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PBPR_RS14670	COG2888	peptidyl-tyrosine sulfation
PBPR_RS14675	COG0495	leucyl-tRNA aminoacylation
PBPR_RS14680	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
PBPR_RS14685	COG1466	dna polymerase III delta subunit
PBPR_RS14690	COG0799	negative regulation of ribosome biogenesis
PBPR_RS14695	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PBPR_RS14700	COG0768	penicillin binding
PBPR_RS14705	COG0772	Belongs to the SEDS family
PBPR_RS14710	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PBPR_RS14715	COG1686	Belongs to the peptidase S11 family
PBPR_RS14725	COG0321	lipoyl(octanoyl) transferase activity
PBPR_RS14730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PBPR_RS14735	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PBPR_RS14740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PBPR_RS14745	COG2716	regulation of RNA biosynthetic process
PBPR_RS14750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PBPR_RS14765	COG4783	chaperone-mediated protein folding
PBPR_RS14770	COG1393	Belongs to the ArsC family
PBPR_RS14800	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PBPR_RS14805	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PBPR_RS14810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PBPR_RS14815	COG0121	glutamine amidotransferase
PBPR_RS14820	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PBPR_RS14825	COG0659	secondary active sulfate transmembrane transporter activity
PBPR_RS14830	COG1960	acyl-CoA dehydrogenase activity
PBPR_RS14845	COG0328	RNA-DNA hybrid ribonuclease activity
PBPR_RS14850	COG2226	methyltransferase
PBPR_RS14855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PBPR_RS14860	COG1388	LysM domain
PBPR_RS14860	COG0741	lytic transglycosylase activity
PBPR_RS14925	COG4608	Belongs to the ABC transporter superfamily
PBPR_RS14930	COG0444	Belongs to the ABC transporter superfamily
PBPR_RS14940	COG4239	(ABC) transporter, permease
PBPR_RS14945	COG4174	ABC transporter (Permease)
PBPR_RS14950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PBPR_RS14955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PBPR_RS14960	COG2011	ABC-type metal ion transport system permease component
PBPR_RS14965	COG1464	Belongs to the NlpA lipoprotein family
PBPR_RS14970	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PBPR_RS14975	COG1720	tRNA m6t6A37 methyltransferase activity
PBPR_RS14980	COG0442	prolyl-tRNA aminoacylation
PBPR_RS15005	COG0733	neurotransmitter:sodium symporter activity
PBPR_RS15015	COG0037	tRNA processing
PBPR_RS15020	COG0825	malonyl-CoA metabolic process
PBPR_RS15025	COG0587	DNA-directed DNA polymerase activity
PBPR_RS15030	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PBPR_RS15035	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBPR_RS15045	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PBPR_RS15050	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBPR_RS15055	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
PBPR_RS15060	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PBPR_RS15065	COG0750	zinc metalloprotease
PBPR_RS15070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PBPR_RS15075	COG0575	Belongs to the CDS family
PBPR_RS15080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PBPR_RS15085	COG0233	cytoplasmic translational termination
PBPR_RS15090	COG0528	UMP kinase activity
PBPR_RS15095	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PBPR_RS15100	COG0052	Belongs to the universal ribosomal protein uS2 family
PBPR_RS15105	COG0024	Methionine aminopeptidase
PBPR_RS15110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PBPR_RS15120	COG0716	FMN binding
PBPR_RS15125	COG0564	pseudouridine synthase activity
PBPR_RS15130	COG3098	single-species biofilm formation
PBPR_RS15165	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
PBPR_RS15175	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PBPR_RS15175	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PBPR_RS15190	COG1611	Belongs to the LOG family
PBPR_RS15195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PBPR_RS15200	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PBPR_RS15205	COG2363	Small membrane protein
PBPR_RS15215	COG0583	DNA-binding transcription factor activity
PBPR_RS15220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PBPR_RS15225	COG2166	iron-sulfur cluster assembly
PBPR_RS15230	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PBPR_RS15235	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PBPR_RS15245	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PBPR_RS15245	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PBPR_RS15250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PBPR_RS15255	COG1074	ATP-dependent DNA helicase activity
PBPR_RS15260	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PBPR_RS15280	COG3141	response to X-ray
PBPR_RS15285	COG2171	N-acyltransferase activity
PBPR_RS15295	COG2814	Major facilitator Superfamily
PBPR_RS15310	COG2801	Transposase and inactivated derivatives
PBPR_RS15320	COG3335	DDE superfamily endonuclease
PBPR_RS15360	COG0542	response to heat
PBPR_RS15370	COG1496	oxidoreductase activity
PBPR_RS15380	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PBPR_RS15385	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PBPR_RS15390	COG0077	Prephenate dehydratase
PBPR_RS15390	COG1605	Chorismate mutase
PBPR_RS15395	COG0287	Prephenate dehydrogenase
PBPR_RS15395	COG1605	Chorismate mutase
PBPR_RS15400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PBPR_RS15405	COG3275	phosphorelay sensor kinase activity
PBPR_RS15410	COG2964	Protein conserved in bacteria
PBPR_RS15420	COG0251	oxidation-reduction process
PBPR_RS15425	COG2271	Major facilitator Superfamily
PBPR_RS15440	COG3279	Response regulator of the LytR AlgR family
PBPR_RS15450	COG1966	Carbon starvation protein
PBPR_RS15455	COG0335	large ribosomal subunit rRNA binding
PBPR_RS15460	COG0336	Belongs to the RNA methyltransferase TrmD family
PBPR_RS15465	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PBPR_RS15470	COG0228	four-way junction DNA binding
PBPR_RS15475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PBPR_RS15480	COG4137	Cytochrome C assembly protein
PBPR_RS15485	COG4536	flavin adenine dinucleotide binding
PBPR_RS15490	COG1854	S-ribosylhomocysteine lyase activity
PBPR_RS15500	COG2918	glutathione biosynthetic process
PBPR_RS15505	COG0612	Peptidase, M16
PBPR_RS15510	COG1238	metal cluster binding
PBPR_RS15515	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
PBPR_RS15520	COG5016	pyruvate
PBPR_RS15520	COG0511	ligase activity, forming carbon-carbon bonds
PBPR_RS15525	COG3630	sodium ion export across plasma membrane
PBPR_RS15595	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PBPR_RS15600	COG0527	aspartate kinase activity
PBPR_RS15605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PBPR_RS15610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PBPR_RS15615	COG1546	Belongs to the CinA family
PBPR_RS15620	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PBPR_RS15625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PBPR_RS15635	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PBPR_RS15640	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PBPR_RS15645	COG0585	pseudouridine synthase activity
PBPR_RS15650	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PBPR_RS15655	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PBPR_RS15660	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PBPR_RS15665	COG0148	phosphopyruvate hydratase activity
PBPR_RS15670	COG0504	CTP synthase activity
PBPR_RS15675	COG3956	TIGRFAM MazG family protein
PBPR_RS15680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PBPR_RS15685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PBPR_RS15690	COG3437	response regulator, receiver
PBPR_RS15690	COG4999	Histidine kinase
PBPR_RS15690	COG2205	protein histidine kinase activity
PBPR_RS15690	COG3850	Histidine kinase
PBPR_RS15695	COG0736	holo-[acyl-carrier-protein] synthase activity
PBPR_RS15700	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PBPR_RS15705	COG1381	Involved in DNA repair and RecF pathway recombination
PBPR_RS15710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PBPR_RS15715	COG0571	ribonuclease III activity
PBPR_RS15725	COG0481	GTPase activity
PBPR_RS15730	COG3086	response to oxidative stress
PBPR_RS15735	COG3026	antisigma factor binding
PBPR_RS15745	COG1595	DNA-templated transcription, initiation
PBPR_RS15755	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PBPR_RS15765	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PBPR_RS15770	COG0354	folic acid binding
PBPR_RS15830	COG0583	DNA-binding transcription factor activity
PBPR_RS15835	COG2991	Protein conserved in bacteria
PBPR_RS15845	COG1342	Belongs to the UPF0251 family
PBPR_RS15855	COG0509	glycine decarboxylation via glycine cleavage system
PBPR_RS15860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PBPR_RS15865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PBPR_RS15875	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PBPR_RS15880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PBPR_RS15885	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PBPR_RS15900	COG0583	DNA-binding transcription factor activity
PBPR_RS15915	COG0668	transmembrane transport
PBPR_RS15920	COG0191	fructose-bisphosphate aldolase activity
PBPR_RS15925	COG0126	phosphoglycerate kinase activity
PBPR_RS15930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PBPR_RS15935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PBPR_RS15940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PBPR_RS15950	COG2356	endonuclease I
PBPR_RS15955	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PBPR_RS15960	COG0189	ligase activity
PBPR_RS15965	COG1678	Uncharacterized ACR, COG1678
PBPR_RS15970	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PBPR_RS15990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PBPR_RS15995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PBPR_RS16005	COG1872	DUF167
PBPR_RS16015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PBPR_RS16020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PBPR_RS16030	COG2066	Belongs to the glutaminase family
PBPR_RS16035	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PBPR_RS16040	COG1194	a g-specific adenine glycosylase
PBPR_RS16045	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PBPR_RS16050	COG0741	lytic transglycosylase activity
PBPR_RS16100	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PBPR_RS16105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PBPR_RS16110	COG1643	Atp-dependent helicase
PBPR_RS16120	COG1489	DNA binding
PBPR_RS16125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PBPR_RS16130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PBPR_RS16140	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PBPR_RS16145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PBPR_RS16150	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PBPR_RS16155	COG0842	Transport permease protein
PBPR_RS16160	COG1131	(ABC) transporter
PBPR_RS16165	COG0288	reversible hydration of carbon dioxide
PBPR_RS16180	COG3842	ATPase activity
PBPR_RS16190	COG1840	ABC-type Fe3 transport system, periplasmic component
PBPR_RS16195	COG0004	ammonium transporteR
PBPR_RS16200	COG0347	Belongs to the P(II) protein family
PBPR_RS16205	COG3112	Uncharacterised protein family (UPF0231)
PBPR_RS16210	COG3835	regulator
PBPR_RS16215	COG2610	gluconate transmembrane transporter activity
PBPR_RS16220	COG1929	Belongs to the glycerate kinase type-1 family
PBPR_RS16230	COG1752	Esterase of the alpha-beta hydrolase superfamily
PBPR_RS16235	COG0840	transmembrane signaling receptor activity
PBPR_RS16240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PBPR_RS16245	COG0508	dehydrogenase complex catalyzes the overall conversion of
PBPR_RS16250	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PBPR_RS16255	COG2186	Transcriptional regulator
PBPR_RS16265	COG0157	Belongs to the NadC ModD family
PBPR_RS16275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PBPR_RS16280	COG1459	type II secretion system
PBPR_RS16290	COG0237	dephospho-CoA kinase activity
PBPR_RS16295	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
PBPR_RS16300	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PBPR_RS16305	COG0494	nUDIX hydrolase
PBPR_RS16310	COG0653	protein targeting
PBPR_RS16320	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PBPR_RS16325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PBPR_RS16330	COG0849	cell division
PBPR_RS16335	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PBPR_RS16340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PBPR_RS16345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PBPR_RS16350	COG0772	Belongs to the SEDS family
PBPR_RS16355	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PBPR_RS16360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PBPR_RS16365	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PBPR_RS16370	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PBPR_RS16375	COG0768	penicillin binding
PBPR_RS16380	COG3116	cell division
PBPR_RS16385	COG0275	rRNA processing
PBPR_RS16390	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PBPR_RS16395	COG3107	peptidoglycan biosynthetic process
PBPR_RS16400	COG0792	nuclease activity
PBPR_RS16415	COG2969	positive regulation of protein catabolic process
PBPR_RS16420	COG0625	glutathione transferase activity
PBPR_RS16425	COG2857	Cytochrome c1
PBPR_RS16430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PBPR_RS16435	COG0723	plastoquinol--plastocyanin reductase activity
PBPR_RS16440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PBPR_RS16445	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PBPR_RS16450	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PBPR_RS16455	COG3105	Protein conserved in bacteria
PBPR_RS16465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PBPR_RS16470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PBPR_RS16475	COG5007	Belongs to the BolA IbaG family
PBPR_RS16480	COG3113	response to antibiotic
PBPR_RS16485	COG2854	intermembrane phospholipid transfer
PBPR_RS16490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PBPR_RS16495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PBPR_RS16500	COG1127	ABC transporter
PBPR_RS16510	COG0517	IMP dehydrogenase activity
PBPR_RS16510	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PBPR_RS16515	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PBPR_RS16520	COG3117	lipopolysaccharide transmembrane transporter activity
PBPR_RS16525	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PBPR_RS16530	COG1137	ATPase activity
PBPR_RS16540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PBPR_RS16550	COG1660	Displays ATPase and GTPase activities
PBPR_RS16555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PBPR_RS16560	COG2239	Acts as a magnesium transporter
PBPR_RS16565	COG0312	modulator of DNA gyrase
PBPR_RS16575	COG0312	modulator of DNA gyrase
PBPR_RS16580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PBPR_RS16585	COG3164	Protein of unknown function
PBPR_RS16590	COG1530	ribonuclease E activity
PBPR_RS16595	COG0424	maF-like protein
PBPR_RS16600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PBPR_RS16605	COG1792	Involved in formation and maintenance of cell shape
PBPR_RS16610	COG1077	Cell shape determining protein MreB Mrl
PBPR_RS16645	COG2165	general secretion pathway protein
PBPR_RS16655	COG1459	type II secretion system
PBPR_RS16660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PBPR_RS16670	COG3409	Peptidoglycan-binding domain 1 protein
PBPR_RS16670	COG3267	Type II secretory pathway component ExeA
PBPR_RS16695	COG2199	diguanylate cyclase activity
PBPR_RS16695	COG2200	EAL domain
PBPR_RS16705	COG0629	single-stranded DNA binding
PBPR_RS16710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PBPR_RS16720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PBPR_RS16725	COG0527	aspartate kinase activity
PBPR_RS16730	COG1410	methionine synthase
PBPR_RS16730	COG0646	methionine synthase
PBPR_RS16745	COG3335	DDE superfamily endonuclease
PBPR_RS16755	COG3335	DDE superfamily endonuclease
PBPR_RS16795	COG1218	3'(2'),5'-bisphosphate nucleotidase
PBPR_RS16800	COG0529	Catalyzes the synthesis of activated sulfate
PBPR_RS16805	COG0471	metal ion transport
PBPR_RS16805	COG3273	potassium ion transport
PBPR_RS16810	COG2895	sulfate adenylyltransferase (ATP) activity
PBPR_RS16815	COG0175	sulfate reduction
PBPR_RS16820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PBPR_RS16820	COG1648	precorrin-2 dehydrogenase activity
PBPR_RS16825	COG0737	Belongs to the 5'-nucleotidase family
PBPR_RS16835	COG2153	protein acetylation
PBPR_RS16840	COG3061	Opacity-associated protein A
PBPR_RS16845	COG0545	Peptidyl-prolyl cis-trans isomerase
PBPR_RS16855	COG0175	sulfate reduction
PBPR_RS16860	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PBPR_RS16865	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PBPR_RS16890	COG0735	belongs to the Fur family
PBPR_RS16900	COG0166	Belongs to the GPI family
PBPR_RS16910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PBPR_RS16940	COG0359	binds to the 23S rRNA
PBPR_RS16945	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PBPR_RS16950	COG2965	DNA replication, synthesis of RNA primer
PBPR_RS16955	COG0360	Binds together with S18 to 16S ribosomal RNA
PBPR_RS16960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PBPR_RS16965	COG0557	exoribonuclease II activity
PBPR_RS16970	COG1959	2 iron, 2 sulfur cluster binding
PBPR_RS16975	COG1017	nitric oxide dioxygenase activity
PBPR_RS16975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PBPR_RS16980	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
PBPR_RS16985	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PBPR_RS16990	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
PBPR_RS16995	COG0330	HflC and HflK could
PBPR_RS17000	COG0330	HflC and HflK could
PBPR_RS17005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PBPR_RS17010	COG1923	regulation of RNA biosynthetic process
PBPR_RS17015	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PBPR_RS17020	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PBPR_RS17025	COG0860	N-Acetylmuramoyl-L-alanine amidase
PBPR_RS17030	COG0802	atpase or kinase
PBPR_RS17035	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PBPR_RS17035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PBPR_RS17040	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PBPR_RS17110	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PBPR_RS17115	COG1162	GTPase activity
PBPR_RS17120	COG0688	phosphatidylethanolamine metabolic process
PBPR_RS17125	COG0471	metal ion transport
PBPR_RS17140	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
PBPR_RS17145	COG1053	succinate dehydrogenase
PBPR_RS17150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PBPR_RS17155	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
PBPR_RS17160	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
PBPR_RS17165	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PBPR_RS17170	COG1509	lysine 2,3-aminomutase activity
PBPR_RS17180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PBPR_RS17185	COG0189	ligase activity
PBPR_RS17190	COG0459	protein refolding
PBPR_RS17195	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PBPR_RS17200	COG0534	Mate efflux family protein
PBPR_RS17210	COG1027	Aspartate ammonia-lyase
PBPR_RS17215	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PBPR_RS17225	COG4232	protein-disulfide reductase activity
PBPR_RS17235	COG2095	MarC family integral membrane protein
PBPR_RS17245	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBPR_RS17250	COG0784	Response regulator, receiver
PBPR_RS17250	COG2205	protein histidine kinase activity
PBPR_RS17255	COG2814	Major facilitator Superfamily
PBPR_RS17270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PBPR_RS17275	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PBPR_RS17280	COG0511	ligase activity, forming carbon-carbon bonds
PBPR_RS17285	COG0439	Biotin carboxylase
PBPR_RS17290	COG3924	membrane
PBPR_RS17295	COG4145	pantothenate transmembrane transporter activity
PBPR_RS17300	COG2264	protein methyltransferase activity
PBPR_RS17310	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
PBPR_RS17330	COG3123	guanosine phosphorylase activity
PBPR_RS17350	COG0151	Belongs to the GarS family
PBPR_RS17365	COG1253	flavin adenine dinucleotide binding
PBPR_RS17380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PBPR_RS17385	COG1573	uracil-dna glycosylase
PBPR_RS17390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PBPR_RS17395	COG2816	NAD+ diphosphatase activity
PBPR_RS17400	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
PBPR_RS17405	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PBPR_RS17410	COG0085	RNA polymerase activity
PBPR_RS17415	COG0222	ribosome binding
PBPR_RS17420	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PBPR_RS17425	COG0081	regulation of translation
PBPR_RS17430	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PBPR_RS17440	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PBPR_RS17445	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PBPR_RS17480	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PBPR_RS17490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PBPR_RS17510	COG3547	Transposase (IS116 IS110 IS902 family)
PBPR_RS17565	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PBPR_RS17575	COG4206	TonB-dependent receptor
PBPR_RS17580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PBPR_RS17595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PBPR_RS17600	COG1218	3'(2'),5'-bisphosphate nucleotidase
PBPR_RS17605	COG0494	nUDIX hydrolase
PBPR_RS17615	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
PBPR_RS17620	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
PBPR_RS17625	COG3156	type II secretion system protein K
PBPR_RS17630	COG4795	General secretion pathway protein
PBPR_RS17635	COG2165	general secretion pathway protein
PBPR_RS17640	COG2165	general secretion pathway protein
PBPR_RS17645	COG2165	general secretion pathway protein
PBPR_RS17650	COG1459	type II secretion system
PBPR_RS17655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PBPR_RS17665	COG3031	protein transport across the cell outer membrane
PBPR_RS17670	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PBPR_RS17675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PBPR_RS17680	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PBPR_RS17690	COG0456	acetyltransferase
PBPR_RS17695	COG1490	D-aminoacyl-tRNA deacylase activity
PBPR_RS17700	COG1295	ribonuclease BN
PBPR_RS17710	COG1217	gtp-binding protein TYPA
PBPR_RS17715	COG0174	glutamine synthetase
PBPR_RS17725	COG3852	Histidine kinase
PBPR_RS17750	COG3078	GTPase activator activity
PBPR_RS17765	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PBPR_RS17770	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PBPR_RS17770	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PBPR_RS17775	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PBPR_RS17785	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PBPR_RS17795	COG0514	ATP-dependent DNA helicase (RecQ)
PBPR_RS17800	COG2962	Rard protein
PBPR_RS17805	COG3708	Transcriptional regulator
PBPR_RS17805	COG2207	Transcriptional regulator
PBPR_RS17810	COG1280	lysine exporter protein (LysE YggA)
PBPR_RS17820	COG0210	DNA helicase
PBPR_RS17835	COG3220	belongs to the UPF0276 family
PBPR_RS17850	COG1011	Hydrolase
PBPR_RS17855	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PBPR_RS17865	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PBPR_RS17870	COG0019	diaminopimelate decarboxylase activity
PBPR_RS17875	COG1965	Belongs to the frataxin family
PBPR_RS17880	COG4467	Involved in initiation control of chromosome replication
PBPR_RS17895	COG1587	Uroporphyrinogen-III synthase
PBPR_RS17900	COG2959	enzyme of heme biosynthesis
PBPR_RS17905	COG3071	HemY protein
PBPR_RS17915	COG0742	ribosomal rna small subunit methyltransferase
PBPR_RS17920	COG5001	Diguanylate cyclase
PBPR_RS17920	COG5002	protein histidine kinase activity
PBPR_RS17925	COG1522	sequence-specific DNA binding
PBPR_RS17940	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PBPR_RS17955	COG3118	belongs to the thioredoxin family
PBPR_RS17960	COG0513	Belongs to the DEAD box helicase family
PBPR_RS17965	COG0248	Ppx GppA phosphatase
PBPR_RS17975	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PBPR_RS17980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PBPR_RS17985	COG3314	Sporulation integral membrane protein YlbJ
PBPR_RS18010	COG4467	Involved in initiation control of chromosome replication
PBPR_RS18020	COG3335	DDE superfamily endonuclease
PBPR_RS18095	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PBPR_RS18105	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PBPR_RS18110	COG0408	coproporphyrinogen oxidase activity
PBPR_RS18115	COG0009	L-threonylcarbamoyladenylate synthase
PBPR_RS18125	COG0551	DNA topoisomerase type I activity
PBPR_RS18130	COG2922	Belongs to the Smg family
PBPR_RS18135	COG0758	DNA mediated transformation
PBPR_RS18140	COG1652	LysM domain
PBPR_RS18145	COG0242	peptide deformylase activity
PBPR_RS18150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PBPR_RS18155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PBPR_RS18155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PBPR_RS18160	COG0569	domain protein
PBPR_RS18165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PBPR_RS18170	COG1272	protein, Hemolysin III
PBPR_RS18180	COG2186	Transcriptional regulator
PBPR_RS18185	COG3084	Protein conserved in bacteria
PBPR_RS18195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PBPR_RS18200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PBPR_RS18205	COG1683	Conserved Protein
PBPR_RS18210	COG0606	chelatase, subunit chli
PBPR_RS18220	COG3978	acetolactate synthase activity
PBPR_RS18225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PBPR_RS18230	COG0129	dihydroxy-acid dehydratase activity
PBPR_RS18250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PBPR_RS18255	COG1349	DNA-binding transcription factor activity
PBPR_RS18260	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PBPR_RS18265	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PBPR_RS18270	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PBPR_RS18275	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PBPR_RS18280	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PBPR_RS18285	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PBPR_RS18290	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PBPR_RS18300	COG0356	it plays a direct role in the translocation of protons across the membrane
PBPR_RS18305	COG3312	ion transport
PBPR_RS18310	COG1475	DNA binding
PBPR_RS18315	COG1192	Involved in chromosome partitioning
PBPR_RS18320	COG0357	Ribosomal RNA small subunit methyltransferase G
PBPR_RS18325	COG0445	tRNA wobble uridine modification
PBPR_RS18355	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PBPR_RS18590	COG1024	Enoyl-CoA hydratase
PBPR_RS18590	COG1250	3-hydroxyacyl-CoA dehydrogenase
PBPR_RS19020	COG0552	protein localization to endoplasmic reticulum
PBPR_RS19215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PBPR_RS19230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PBPR_RS19340	COG0859	PFAM glycosyl transferase family 9
PBPR_RS19550	COG0527	aspartate kinase activity
PBPR_RS19550	COG0460	homoserine dehydrogenase
PBPR_RS20460	COG4213	ABC transporter substrate-binding protein
PBPR_RS20615	COG0726	polysaccharide deacetylase
PBPR_RS20855	COG0069	glutamate synthase activity
PBPR_RS20855	COG0067	glutamate synthase
PBPR_RS20855	COG0070	glutamate synthase
PBPR_RS20860	COG0070	glutamate synthase
PBPR_RS20860	COG0069	glutamate synthase activity
PBPR_RS20860	COG0067	glutamate synthase
PBPR_RS20865	COG0070	glutamate synthase
PBPR_RS20865	COG0069	glutamate synthase activity
PBPR_RS20865	COG0067	glutamate synthase
PBPR_RS20905	COG0070	glutamate synthase
PBPR_RS20905	COG0067	glutamate synthase
PBPR_RS20905	COG0069	glutamate synthase activity
PBPR_RS20950	COG0527	aspartate kinase activity
PBPR_RS20950	COG0460	homoserine dehydrogenase
PBPR_RS21035	COG4974	Belongs to the 'phage' integrase family
PBPR_RS21160	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PBPR_RS21270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PBPR_RS21290	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PBPR_RS21805	COG5002	protein histidine kinase activity
PBPR_RS21840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PBPR_RS22145	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PBPR_RS22200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PBPR_RS22400	COG1073	alpha beta
PBPR_RS22410	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PBPR_RS22415	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PBPR_RS22850	COG1766	The M ring may be actively involved in energy transduction
PBPR_RS22975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PBPR_RS23090	COG2890	protein-(glutamine-N5) methyltransferase activity
PBPR_RS23120	COG1132	(ABC) transporter
PBPR_RS23145	COG1946	Acyl-CoA thioesterase
PBPR_RS23445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PBPR_RS23475	COG1846	Transcriptional regulator
PBPR_RS23475	COG1940	carbohydrate kinase activity
PBPR_RS23785	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PBPR_RS23895	COG2226	methyltransferase
PBPR_RS24255	COG1674	ftsk spoiiie
PBPR_RS24425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PBPR_RS24515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PBPR_RS24695	COG4690	dipeptidase activity
PBPR_RS24740	COG2897	thiosulfate sulfurtransferase activity
PBPR_RS25265	COG3969	phosphoadenosine phosphosulfate
PBPR_RS25480	COG4467	Involved in initiation control of chromosome replication
PBPR_RS25520	COG0840	transmembrane signaling receptor activity
PBPR_RS25835	COG1115	amino acid carrier protein
PBPR_RS25960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PBPR_RS26045	COG0243	molybdopterin cofactor binding
PBPR_RS26255	COG0076	glutamate decarboxylase activity
PBPR_RS26980	COG2433	Pfam Transposase IS66
PBPR_RS27230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PBPR_RS27230	COG1028	Short-chain dehydrogenase reductase Sdr
PBPR_RS27230	COG3321	synthase
PBPR_RS27230	COG4221	oxidoreductase activity
PBPR_RS27640	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PBPR_RS27650	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PBPR_RS27655	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PBPR_RS27705	COG1643	Atp-dependent helicase
PBPR_RS27715	COG0826	peptidase U32
PBPR_RS28170	COG1686	Belongs to the peptidase S11 family
PBPR_RS28420	COG2204	response regulator
PBPR_RS28675	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PBPR_RS28705	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PBPR_RS29030	COG0438	transferase activity, transferring glycosyl groups
PBPR_RS29045	COG1366	Belongs to the anti-sigma-factor antagonist family
PBPR_RS29050	COG3209	COG3209 Rhs family protein
PBPR_RS29055	COG0840	transmembrane signaling receptor activity
PBPR_RS29065	COG1763	Mo-molybdopterin cofactor biosynthetic process
PBPR_RS29220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PBPR_RS29310	COG4890	Cyd operon protein YbgT