L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 598 4.7E-290 T 09-03-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 PRINTS PR00301 70kDa heat shock protein signature 327 343 2.9E-77 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 PRINTS PR00301 70kDa heat shock protein signature 383 402 2.9E-77 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.9E-77 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.9E-77 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.9E-77 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 PRINTS PR00301 70kDa heat shock protein signature 195 205 2.9E-77 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 PRINTS PR00301 70kDa heat shock protein signature 464 480 2.9E-77 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 PRINTS PR00301 70kDa heat shock protein signature 358 378 2.9E-77 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 PRINTS PR00301 70kDa heat shock protein signature 136 156 2.9E-77 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 642 36.639 T 09-03-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 Gene3D G3DSA:3.30.420.40 4 52 5.1E-61 T 09-03-2017 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 Gene3D G3DSA:3.30.420.40 117 189 5.1E-61 T 09-03-2017 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 Gene3D G3DSA:2.60.34.10 385 526 3.1E-72 T 09-03-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 Gene3D G3DSA:3.30.420.40 312 354 3.3E-34 T 09-03-2017 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 Gene3D G3DSA:3.30.420.40 190 222 3.3E-34 T 09-03-2017 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 Gene3D G3DSA:1.20.1270.10 527 598 7.2E-29 T 09-03-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 Gene3D G3DSA:3.90.640.10 223 307 2.6E-29 T 09-03-2017 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 Gene3D G3DSA:3.30.30.30 53 102 6.4E-19 T 09-03-2017 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 330 344 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 Pfam PF00012 Hsp70 protein 4 598 2.5E-257 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 189 202 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 SUPERFAMILY SSF53067 4 182 2.85E-60 T 09-03-2017 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 SUPERFAMILY SSF100920 379 535 1.29E-62 T 09-03-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 SUPERFAMILY SSF100934 502 600 2.49E-21 T 09-03-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 L21SP3_RS06650 e36f995256930e5893cb9c94ecbe54cf 643 SUPERFAMILY SSF53067 183 375 2.18E-63 T 09-03-2017 L21SP3_RS03610 441fa8748486f592922b24d3f1b798e9 653 Pfam PF14509 Glycosyl-hydrolase 97 C-terminal, oligomerisation 555 650 1.7E-31 T 09-03-2017 IPR029483 Glycosyl-hydrolase 97, C-terminal oligomerisation domain L21SP3_RS03610 441fa8748486f592922b24d3f1b798e9 653 Pfam PF10566 Glycoside hydrolase 97 292 553 4.1E-108 T 09-03-2017 IPR019563 Glycosyl-hydrolase 97, catalytic domain L21SP3_RS03610 441fa8748486f592922b24d3f1b798e9 653 Gene3D G3DSA:3.20.20.70 301 439 1.3E-9 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS03610 441fa8748486f592922b24d3f1b798e9 653 Pfam PF14508 Glycosyl-hydrolase 97 N-terminal 26 287 3.0E-51 T 09-03-2017 IPR029486 Glycosyl-hydrolase 97, N-terminal domain L21SP3_RS03610 441fa8748486f592922b24d3f1b798e9 653 SUPERFAMILY SSF51445 290 540 2.21E-28 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS09920 dc25d93837560c87789a15965d7bab27 1080 Pfam PF00754 F5/8 type C domain 950 1074 5.1E-14 T 09-03-2017 IPR000421 Coagulation factor 5/8 C-terminal domain L21SP3_RS09920 dc25d93837560c87789a15965d7bab27 1080 Gene3D G3DSA:2.60.40.320 206 320 2.4E-8 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS09920 dc25d93837560c87789a15965d7bab27 1080 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 322 494 4.6E-8 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS09920 dc25d93837560c87789a15965d7bab27 1080 SUPERFAMILY SSF51445 316 632 3.45E-54 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS09920 dc25d93837560c87789a15965d7bab27 1080 SUPERFAMILY SSF49303 217 319 7.77E-5 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS09920 dc25d93837560c87789a15965d7bab27 1080 Gene3D G3DSA:2.60.120.260 947 1077 8.1E-24 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09920 dc25d93837560c87789a15965d7bab27 1080 SUPERFAMILY SSF49785 17 69 1.7E-31 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09920 dc25d93837560c87789a15965d7bab27 1080 SUPERFAMILY SSF49785 108 213 1.7E-31 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09920 dc25d93837560c87789a15965d7bab27 1080 Pfam PF00703 Glycosyl hydrolases family 2 217 319 5.7E-11 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS09920 dc25d93837560c87789a15965d7bab27 1080 SUPERFAMILY SSF49785 944 1076 2.41E-23 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09920 dc25d93837560c87789a15965d7bab27 1080 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 23 200 5.7E-15 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS09920 dc25d93837560c87789a15965d7bab27 1080 Gene3D G3DSA:3.20.20.80 322 632 3.3E-39 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS09920 dc25d93837560c87789a15965d7bab27 1080 Gene3D G3DSA:2.60.120.260 19 205 3.9E-33 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS02965 17302f3a9a0127f19e42811597cb20db 469 Pfam PF02321 Outer membrane efflux protein 69 249 8.6E-19 T 09-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP3_RS02965 17302f3a9a0127f19e42811597cb20db 469 Pfam PF02321 Outer membrane efflux protein 278 459 7.2E-23 T 09-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP3_RS02965 17302f3a9a0127f19e42811597cb20db 469 Gene3D G3DSA:1.20.1600.10 57 464 4.7E-80 T 09-03-2017 L21SP3_RS02965 17302f3a9a0127f19e42811597cb20db 469 SUPERFAMILY SSF56954 59 463 9.94E-87 T 09-03-2017 L21SP3_RS02965 17302f3a9a0127f19e42811597cb20db 469 SUPERFAMILY SSF56954 2 32 9.94E-87 T 09-03-2017 L21SP3_RS02965 17302f3a9a0127f19e42811597cb20db 469 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 460 2.8E-78 T 09-03-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 L21SP3_RS08495 574978a4983a658752a82a0fa4cfc89e 261 Pfam PF01695 IstB-like ATP binding protein 59 235 4.3E-62 T 09-03-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 L21SP3_RS08495 574978a4983a658752a82a0fa4cfc89e 261 SMART SM00382 103 238 4.5E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS08495 574978a4983a658752a82a0fa4cfc89e 261 PIRSF PIRSF003073 4 257 5.6E-78 T 09-03-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein L21SP3_RS08495 574978a4983a658752a82a0fa4cfc89e 261 Gene3D G3DSA:3.40.50.300 75 234 2.5E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08495 574978a4983a658752a82a0fa4cfc89e 261 SUPERFAMILY SSF52540 74 234 2.46E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 454 3.8E-142 T 09-03-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 272 8.1E-34 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 8.1E-34 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 8.1E-34 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 8.1E-34 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 8.1E-34 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 444 1.4E-25 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PIRSF PIRSF000350 1 447 2.7E-71 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 Gene3D G3DSA:3.50.50.60 254 329 1.9E-15 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 Gene3D G3DSA:3.50.50.60 2 144 1.2E-39 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 3.6E-57 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.6E-57 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 3.6E-57 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 3.6E-57 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 3.6E-57 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 3.6E-57 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 306 3.6E-57 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 3.6E-57 T 09-03-2017 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 316 9.0E-61 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 Gene3D G3DSA:3.30.390.30 330 454 4.6E-33 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 SUPERFAMILY SSF51905 2 328 8.1E-54 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 Gene3D G3DSA:3.50.50.60 147 253 1.5E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 SUPERFAMILY SSF55424 335 456 1.63E-32 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 L21SP3_RS06435 6a496474e2a574dfdbeb225e89bc1ac6 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 09-03-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 L21SP3_RS10560 3b5056f3cc8acf05fcc1d4e8c6097eec 366 Gene3D G3DSA:3.40.50.1110 184 363 1.3E-15 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS10560 3b5056f3cc8acf05fcc1d4e8c6097eec 366 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 183 359 3.4E-47 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS10560 3b5056f3cc8acf05fcc1d4e8c6097eec 366 Pfam PF14607 N-terminus of Esterase_SGNH_hydro-type 20 171 2.7E-30 T 09-03-2017 IPR032740 SGNH hydrolase-type esterase, N-terminal L21SP3_RS10560 3b5056f3cc8acf05fcc1d4e8c6097eec 366 SUPERFAMILY SSF52266 178 360 5.8E-22 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 SUPERFAMILY SSF52374 3 138 4.16E-102 T 09-03-2017 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 SUPERFAMILY SSF52374 173 381 4.16E-102 T 09-03-2017 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 Gene3D G3DSA:3.40.50.620 180 374 3.9E-93 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 Gene3D G3DSA:3.40.50.620 4 141 3.9E-93 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 Hamap MF_00098 Methionine--tRNA ligase [metG]. 3 540 39.638 T 09-03-2017 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 530 1.6E-175 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 Gene3D G3DSA:2.20.28.20 142 173 2.1E-17 T 09-03-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 SUPERFAMILY SSF47323 381 585 3.92E-37 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.1E-22 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 PRINTS PR01041 Methionyl-tRNA synthetase signature 286 301 1.1E-22 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 1.1E-22 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 PRINTS PR01041 Methionyl-tRNA synthetase signature 379 390 1.1E-22 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 PRINTS PR01041 Methionyl-tRNA synthetase signature 248 259 1.1E-22 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.1E-22 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 SUPERFAMILY SSF50249 569 673 4.9E-30 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 Gene3D G3DSA:2.40.50.140 567 673 1.6E-38 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 SUPERFAMILY SSF57770 139 173 1.14E-11 T 09-03-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 Pfam PF01588 Putative tRNA binding domain 579 671 5.5E-22 T 09-03-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 Pfam PF08264 Anticodon-binding domain of tRNA 411 501 1.2E-6 T 09-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 Gene3D G3DSA:1.10.730.10 375 529 2.9E-39 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 Pfam PF09334 tRNA synthetases class I (M) 5 391 4.1E-157 T 09-03-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS01355 88097a4879817ca6f263d5842d5172db 674 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 536 673 1.8E-44 T 09-03-2017 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 L21SP3_RS04005 379d2cbd1297c459af4b1d810526f6b3 1409 Gene3D G3DSA:3.20.20.80 66 486 3.4E-49 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS04005 379d2cbd1297c459af4b1d810526f6b3 1409 SUPERFAMILY SSF48208 1326 1404 9.35E-44 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS04005 379d2cbd1297c459af4b1d810526f6b3 1409 SUPERFAMILY SSF48208 936 1288 9.35E-44 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS04005 379d2cbd1297c459af4b1d810526f6b3 1409 Pfam PF12439 Glycogen debranching enzyme N terminal 764 986 3.2E-18 T 09-03-2017 IPR024742 Glycogen debranching enzyme, bacterial and archaeal type, N-terminal L21SP3_RS04005 379d2cbd1297c459af4b1d810526f6b3 1409 SMART SM00642 131 472 2.1E-6 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP3_RS04005 379d2cbd1297c459af4b1d810526f6b3 1409 Pfam PF00128 Alpha amylase, catalytic domain 231 375 3.6E-7 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP3_RS04005 379d2cbd1297c459af4b1d810526f6b3 1409 SUPERFAMILY SSF51445 126 489 1.28E-49 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS04005 379d2cbd1297c459af4b1d810526f6b3 1409 Pfam PF06202 Amylo-alpha-1,6-glucosidase 1033 1402 3.3E-75 T 09-03-2017 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25+3.2.1.33|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 L21SP3_RS02405 b881686f6aba8d352bb01a66c4374860 275 Pfam PF00793 DAHP synthetase I family 8 260 3.1E-65 T 09-03-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 L21SP3_RS02405 b881686f6aba8d352bb01a66c4374860 275 Gene3D G3DSA:3.20.20.70 15 271 4.4E-105 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS02405 b881686f6aba8d352bb01a66c4374860 275 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 16 271 1.3E-109 T 09-03-2017 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 L21SP3_RS02405 b881686f6aba8d352bb01a66c4374860 275 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 11 273 47.653 T 09-03-2017 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 L21SP3_RS02405 b881686f6aba8d352bb01a66c4374860 275 SUPERFAMILY SSF51569 3 272 3.57E-98 T 09-03-2017 L21SP3_RS05010 e7b828d2e5d1813d3fb807d78c30f155 183 Pfam PF01965 DJ-1/PfpI family 3 165 2.1E-45 T 09-03-2017 IPR002818 DJ-1/PfpI L21SP3_RS05010 e7b828d2e5d1813d3fb807d78c30f155 183 SUPERFAMILY SSF52317 3 182 7.77E-48 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS05010 e7b828d2e5d1813d3fb807d78c30f155 183 Gene3D G3DSA:3.40.50.880 1 182 5.7E-57 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS05010 e7b828d2e5d1813d3fb807d78c30f155 183 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 5 178 5.3E-61 T 09-03-2017 IPR006287 Protein deglycase DJ-1 GO:0006517|GO:0030091 L21SP3_RS04435 e1cf048bcef59234b8f5844b2908eca4 205 Hamap MF_01398 ATP synthase subunit b [atpF]. 14 196 11.037 T 09-03-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 L21SP3_RS04435 e1cf048bcef59234b8f5844b2908eca4 205 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 51 196 2.2E-22 T 09-03-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 L21SP3_RS04435 e1cf048bcef59234b8f5844b2908eca4 205 Pfam PF00430 ATP synthase B/B' CF(0) 48 171 9.8E-22 T 09-03-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 L21SP3_RS08635 72ff6c5a3e2883fc7218cc1fdd36cc55 389 PIRSF PIRSF005096 39 389 3.4E-135 T 09-03-2017 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 L21SP3_RS08635 72ff6c5a3e2883fc7218cc1fdd36cc55 389 Pfam PF01263 Aldose 1-epimerase 59 385 1.8E-95 T 09-03-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 L21SP3_RS08635 72ff6c5a3e2883fc7218cc1fdd36cc55 389 Gene3D G3DSA:2.70.98.10 41 388 1.1E-142 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS08635 72ff6c5a3e2883fc7218cc1fdd36cc55 389 SUPERFAMILY SSF74650 46 386 3.68E-117 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP3_RS02040 a141001a39818b9f199be22743f0e0ec 329 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 34 179 3.5E-37 T 09-03-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 L21SP3_RS02040 a141001a39818b9f199be22743f0e0ec 329 Pfam PF13242 HAD-hyrolase-like 138 208 1.6E-12 T 09-03-2017 L21SP3_RS02040 a141001a39818b9f199be22743f0e0ec 329 SUPERFAMILY SSF56784 32 212 1.54E-44 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS02040 a141001a39818b9f199be22743f0e0ec 329 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 34 181 8.1E-33 T 09-03-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 L21SP3_RS02040 a141001a39818b9f199be22743f0e0ec 329 Gene3D G3DSA:3.40.50.1000 23 212 2.2E-56 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS11435 3b0d521e51975a22a0caf94a47af9f22 263 PRINTS PR00394 RHS protein signature 83 103 1.7E-7 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11435 3b0d521e51975a22a0caf94a47af9f22 263 PRINTS PR00394 RHS protein signature 106 125 1.7E-7 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11435 3b0d521e51975a22a0caf94a47af9f22 263 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 55 139 9.8E-26 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 L21SP3_RS01930 58b87f1987dc8f8b9609719458798020 550 Gene3D G3DSA:2.60.120.200 291 497 2.9E-30 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS01930 58b87f1987dc8f8b9609719458798020 550 Gene3D G3DSA:2.60.40.10 204 290 1.4E-10 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS01930 58b87f1987dc8f8b9609719458798020 550 SMART SM00560 358 490 0.0028 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS01930 58b87f1987dc8f8b9609719458798020 550 Pfam PF13927 Immunoglobulin domain 205 278 4.9E-8 T 09-03-2017 L21SP3_RS01930 58b87f1987dc8f8b9609719458798020 550 SUPERFAMILY SSF49899 295 497 8.01E-30 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS01930 58b87f1987dc8f8b9609719458798020 550 SMART SM00409 209 294 1.7E-12 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS01930 58b87f1987dc8f8b9609719458798020 550 SUPERFAMILY SSF48726 203 294 3.04E-12 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS01930 58b87f1987dc8f8b9609719458798020 550 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 344 486 3.2E-21 T 09-03-2017 L21SP3_RS00250 c6669934e29abbc5189a0f87aa33b8b2 626 SUPERFAMILY SSF48371 481 582 1.19E-11 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 L21SP3_RS00250 c6669934e29abbc5189a0f87aa33b8b2 626 Gene3D G3DSA:3.30.1120.10 406 452 3.1E-12 T 09-03-2017 L21SP3_RS00250 c6669934e29abbc5189a0f87aa33b8b2 626 Gene3D G3DSA:3.30.1120.10 336 367 3.1E-12 T 09-03-2017 L21SP3_RS00250 c6669934e29abbc5189a0f87aa33b8b2 626 Gene3D G3DSA:1.25.10.10 495 589 1.7E-7 T 09-03-2017 IPR011989 Armadillo-like helical L21SP3_RS00250 c6669934e29abbc5189a0f87aa33b8b2 626 Pfam PF00884 Sulfatase 31 311 2.1E-39 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS00250 c6669934e29abbc5189a0f87aa33b8b2 626 SUPERFAMILY SSF53649 404 448 3.2E-82 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS00250 c6669934e29abbc5189a0f87aa33b8b2 626 SUPERFAMILY SSF53649 29 365 3.2E-82 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS00250 c6669934e29abbc5189a0f87aa33b8b2 626 Gene3D G3DSA:3.40.720.10 125 324 1.4E-32 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS00250 c6669934e29abbc5189a0f87aa33b8b2 626 Gene3D G3DSA:3.40.720.10 29 124 2.4E-27 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS11115 512a4c70bec757a0f0cc9913ea270949 271 Pfam PF12849 PBP superfamily domain 20 254 7.3E-35 T 09-03-2017 IPR024370 PBP domain L21SP3_RS11115 512a4c70bec757a0f0cc9913ea270949 271 SUPERFAMILY SSF53850 21 270 6.72E-69 T 09-03-2017 L21SP3_RS11115 512a4c70bec757a0f0cc9913ea270949 271 Gene3D G3DSA:3.40.190.10 102 228 7.1E-41 T 09-03-2017 L21SP3_RS11115 512a4c70bec757a0f0cc9913ea270949 271 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 19 268 1.9E-72 T 09-03-2017 IPR011862 Phosphate binding protein GO:0006810 L21SP3_RS10960 e5a7149283352a077ddd6900d794bbed 647 Gene3D G3DSA:3.30.1120.10 405 450 5.0E-15 T 09-03-2017 L21SP3_RS10960 e5a7149283352a077ddd6900d794bbed 647 Gene3D G3DSA:3.30.1120.10 351 367 5.0E-15 T 09-03-2017 L21SP3_RS10960 e5a7149283352a077ddd6900d794bbed 647 SUPERFAMILY SSF53649 403 448 7.85E-80 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS10960 e5a7149283352a077ddd6900d794bbed 647 SUPERFAMILY SSF53649 33 365 7.85E-80 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS10960 e5a7149283352a077ddd6900d794bbed 647 Gene3D G3DSA:3.40.720.10 148 350 7.1E-30 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS10960 e5a7149283352a077ddd6900d794bbed 647 Gene3D G3DSA:3.40.720.10 31 143 4.1E-28 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS10960 e5a7149283352a077ddd6900d794bbed 647 Pfam PF00884 Sulfatase 155 310 2.4E-18 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS10960 e5a7149283352a077ddd6900d794bbed 647 Pfam PF00884 Sulfatase 33 138 4.7E-19 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS09115 9e6cf82bcaf81b663c25de43e71f631a 1002 SUPERFAMILY SSF63446 946 996 6.93E-6 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS09115 9e6cf82bcaf81b663c25de43e71f631a 1002 Gene3D G3DSA:2.60.120.260 812 942 1.3E-15 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09115 9e6cf82bcaf81b663c25de43e71f631a 1002 Pfam PF00754 F5/8 type C domain 825 930 9.2E-10 T 09-03-2017 IPR000421 Coagulation factor 5/8 C-terminal domain L21SP3_RS09115 9e6cf82bcaf81b663c25de43e71f631a 1002 SUPERFAMILY SSF51445 65 378 1.19E-20 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS09115 9e6cf82bcaf81b663c25de43e71f631a 1002 ProSitePatterns PS00018 EF-hand calcium-binding domain. 944 956 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS09115 9e6cf82bcaf81b663c25de43e71f631a 1002 Gene3D G3DSA:3.20.20.80 48 370 8.6E-18 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS09115 9e6cf82bcaf81b663c25de43e71f631a 1002 Pfam PF02057 Glycosyl hydrolase family 59 36 401 3.2E-58 T 09-03-2017 IPR001286 Glycoside hydrolase, family 59 GO:0004336|GO:0006683 KEGG: 00600+3.2.1.46|Reactome: R-HSA-1660662 L21SP3_RS09115 9e6cf82bcaf81b663c25de43e71f631a 1002 Pfam PF02057 Glycosyl hydrolase family 59 441 677 2.0E-11 T 09-03-2017 IPR001286 Glycoside hydrolase, family 59 GO:0004336|GO:0006683 KEGG: 00600+3.2.1.46|Reactome: R-HSA-1660662 L21SP3_RS09115 9e6cf82bcaf81b663c25de43e71f631a 1002 SUPERFAMILY SSF49785 815 940 5.27E-18 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09115 9e6cf82bcaf81b663c25de43e71f631a 1002 Gene3D G3DSA:1.10.1330.10 944 999 3.4E-6 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS09115 9e6cf82bcaf81b663c25de43e71f631a 1002 Gene3D G3DSA:2.60.40.1180 371 466 1.8E-4 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta L21SP3_RS01415 85b94b68bc8f31c3069a036bdf9db3f2 73 Gene3D G3DSA:3.40.50.300 1 69 1.1E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01415 85b94b68bc8f31c3069a036bdf9db3f2 73 SUPERFAMILY SSF52540 2 63 1.78E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01415 85b94b68bc8f31c3069a036bdf9db3f2 73 Pfam PF00005 ABC transporter 19 61 8.2E-10 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS06795 553590209ccb7fcfd0ecf88c9400a33d 477 SUPERFAMILY SSF63418 7 89 1.31E-17 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 L21SP3_RS06795 553590209ccb7fcfd0ecf88c9400a33d 477 SUPERFAMILY SSF53244 324 475 1.07E-41 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS06795 553590209ccb7fcfd0ecf88c9400a33d 477 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 97 120 - T 09-03-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 L21SP3_RS06795 553590209ccb7fcfd0ecf88c9400a33d 477 Gene3D G3DSA:3.40.1390.10 12 84 1.6E-15 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 L21SP3_RS06795 553590209ccb7fcfd0ecf88c9400a33d 477 Gene3D G3DSA:3.90.190.20 327 468 1.2E-49 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS06795 553590209ccb7fcfd0ecf88c9400a33d 477 Pfam PF08245 Mur ligase middle domain 99 302 3.2E-48 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS06795 553590209ccb7fcfd0ecf88c9400a33d 477 Pfam PF02875 Mur ligase family, glutamate ligase domain 324 407 2.7E-19 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS06795 553590209ccb7fcfd0ecf88c9400a33d 477 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 475 31.836 T 09-03-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 L21SP3_RS06795 553590209ccb7fcfd0ecf88c9400a33d 477 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 17 475 3.6E-145 T 09-03-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 L21SP3_RS06795 553590209ccb7fcfd0ecf88c9400a33d 477 SUPERFAMILY SSF53623 90 320 1.7E-64 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS06795 553590209ccb7fcfd0ecf88c9400a33d 477 Gene3D G3DSA:3.40.1190.10 90 326 2.0E-75 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS06795 553590209ccb7fcfd0ecf88c9400a33d 477 Pfam PF01225 Mur ligase family, catalytic domain 18 62 1.7E-7 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 L21SP3_RS06780 7d95eb8e98c85f1acb865b504b4ed423 293 Gene3D G3DSA:3.40.50.150 5 110 6.1E-44 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS06780 7d95eb8e98c85f1acb865b504b4ed423 293 Gene3D G3DSA:3.40.50.150 215 291 6.1E-44 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS06780 7d95eb8e98c85f1acb865b504b4ed423 293 Pfam PF01795 MraW methylase family 3 291 1.6E-97 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS06780 7d95eb8e98c85f1acb865b504b4ed423 293 Gene3D G3DSA:1.10.150.170 113 214 5.3E-34 T 09-03-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS06780 7d95eb8e98c85f1acb865b504b4ed423 293 SUPERFAMILY SSF81799 114 212 6.67E-33 T 09-03-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS06780 7d95eb8e98c85f1acb865b504b4ed423 293 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 5 293 34.624 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS06780 7d95eb8e98c85f1acb865b504b4ed423 293 SUPERFAMILY SSF53335 212 290 1.52E-38 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS06780 7d95eb8e98c85f1acb865b504b4ed423 293 SUPERFAMILY SSF53335 5 113 1.52E-38 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS06780 7d95eb8e98c85f1acb865b504b4ed423 293 PIRSF PIRSF004486 1 293 1.7E-101 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS06780 7d95eb8e98c85f1acb865b504b4ed423 293 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 291 9.1E-91 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS09830 1a66bb7eef90e8710c0971705c8a1fce 127 Gene3D G3DSA:3.30.460.10 15 119 2.2E-30 T 09-03-2017 L21SP3_RS09830 1a66bb7eef90e8710c0971705c8a1fce 127 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 15 117 21.027 T 09-03-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS L21SP3_RS09830 1a66bb7eef90e8710c0971705c8a1fce 127 Pfam PF02410 Ribosomal silencing factor during starvation 21 116 1.5E-22 T 09-03-2017 L21SP3_RS09830 1a66bb7eef90e8710c0971705c8a1fce 127 SUPERFAMILY SSF81301 16 125 5.89E-32 T 09-03-2017 L21SP3_RS09830 1a66bb7eef90e8710c0971705c8a1fce 127 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 22 116 2.5E-28 T 09-03-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 Pfam PF08206 Ribonuclease B OB domain 72 123 1.9E-7 T 09-03-2017 IPR013223 Ribonuclease B, N-terminal OB domain L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 SMART SM00316 623 706 0.0042 T 09-03-2017 IPR022967 RNA-binding domain, S1 L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 59 703 3.2E-137 T 09-03-2017 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 SUPERFAMILY SSF50249 211 622 7.71E-113 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 Pfam PF00773 RNB domain 251 574 8.7E-98 T 09-03-2017 L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 TIGRFAM TIGR02063 RNase_R: ribonuclease R 4 702 4.7E-180 T 09-03-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 SMART SM00955 249 575 1.0E-117 T 09-03-2017 L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 Hamap MF_01895 Ribonuclease R [rnr]. 23 706 44.02 T 09-03-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 SUPERFAMILY SSF50249 129 226 1.41E-7 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 Gene3D G3DSA:2.40.50.140 625 704 2.9E-10 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 Pfam PF00575 S1 RNA binding domain 622 699 1.4E-4 T 09-03-2017 IPR003029 S1 domain GO:0003676 L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 SUPERFAMILY SSF50249 623 697 2.73E-11 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 SUPERFAMILY SSF50249 57 137 2.89E-8 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS09465 46e6a000723036d553a87d9cc692e5b3 748 ProSitePatterns PS01175 Ribonuclease II family signature. 542 566 - T 09-03-2017 IPR022966 Ribonuclease II/R, conserved site L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 Hamap MF_00456 Glutamate 5-kinase [proB]. 8 262 35.128 T 09-03-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 Gene3D G3DSA:3.40.1160.10 4 264 1.2E-55 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 TIGRFAM TIGR01027 proB: glutamate 5-kinase 8 362 1.6E-114 T 09-03-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 PRINTS PR00474 Glutamate 5-kinase family signature 44 58 1.5E-47 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 PRINTS PR00474 Glutamate 5-kinase family signature 213 233 1.5E-47 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 PRINTS PR00474 Glutamate 5-kinase family signature 78 106 1.5E-47 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 PRINTS PR00474 Glutamate 5-kinase family signature 152 179 1.5E-47 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 PRINTS PR00474 Glutamate 5-kinase family signature 118 139 1.5E-47 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 Pfam PF00696 Amino acid kinase family 8 239 1.0E-39 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 SMART SM00359 279 356 2.1E-8 T 09-03-2017 IPR002478 PUA domain GO:0003723 L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 PIRSF PIRSF000729 3 365 2.0E-119 T 09-03-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 SUPERFAMILY SSF88697 279 361 1.74E-13 T 09-03-2017 IPR015947 PUA-like domain L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 Gene3D G3DSA:2.30.130.10 277 343 8.7E-15 T 09-03-2017 IPR015947 PUA-like domain L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 Pfam PF01472 PUA domain 279 347 4.0E-15 T 09-03-2017 IPR002478 PUA domain GO:0003723 L21SP3_RS10150 cbca77ea29bda0f46d8842fc5f80ec3c 366 SUPERFAMILY SSF53633 8 261 1.27E-66 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase L21SP3_RS00800 540eea8260787a253da0001cd4b06402 748 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 538 677 3.3E-14 T 09-03-2017 L21SP3_RS00800 540eea8260787a253da0001cd4b06402 748 SUPERFAMILY SSF49899 471 688 4.65E-22 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00800 540eea8260787a253da0001cd4b06402 748 SUPERFAMILY SSF48726 379 465 3.28E-12 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS00800 540eea8260787a253da0001cd4b06402 748 Gene3D G3DSA:2.60.120.200 514 690 1.8E-15 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00800 540eea8260787a253da0001cd4b06402 748 SMART SM00409 388 473 2.1E-8 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS00800 540eea8260787a253da0001cd4b06402 748 SMART SM00408 394 461 0.0013 T 09-03-2017 IPR003598 Immunoglobulin subtype 2 L21SP3_RS00800 540eea8260787a253da0001cd4b06402 748 Pfam PF13927 Immunoglobulin domain 382 458 2.5E-10 T 09-03-2017 L21SP3_RS00800 540eea8260787a253da0001cd4b06402 748 Gene3D G3DSA:2.60.40.10 382 475 3.2E-12 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 Gene3D G3DSA:2.60.120.260 25 230 6.7E-78 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 Gene3D G3DSA:3.20.20.80 361 640 5.0E-106 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 Pfam PF02929 Beta galactosidase small chain 774 1045 5.2E-79 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 Gene3D G3DSA:2.60.40.320 231 359 4.4E-31 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 71 241 8.4E-42 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 Gene3D G3DSA:2.70.98.10 758 1048 7.2E-94 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 SUPERFAMILY SSF49303 639 748 1.44E-28 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 361 646 1.3E-101 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 SUPERFAMILY SSF49303 243 359 5.76E-26 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 411 436 - T 09-03-2017 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 Pfam PF00703 Glycosyl hydrolases family 2 243 359 7.0E-18 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 475 489 - T 09-03-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 Gene3D G3DSA:2.60.40.320 650 749 5.5E-31 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 PRINTS PR00132 Glycosyl hydrolase family 2 signature 169 184 5.2E-35 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 PRINTS PR00132 Glycosyl hydrolase family 2 signature 475 490 5.2E-35 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 PRINTS PR00132 Glycosyl hydrolase family 2 signature 370 384 5.2E-35 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 PRINTS PR00132 Glycosyl hydrolase family 2 signature 549 564 5.2E-35 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 PRINTS PR00132 Glycosyl hydrolase family 2 signature 401 419 5.2E-35 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 Pfam PF16353 Domain of unknown function(DUF4981) 657 746 9.0E-27 T 09-03-2017 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 SUPERFAMILY SSF49785 30 242 1.82E-61 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 SUPERFAMILY SSF51445 361 643 3.97E-93 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 SUPERFAMILY SSF74650 758 1047 2.09E-83 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP3_RS00765 fcddb1d6e3b782a66794c1e50c2d1b73 1060 SMART SM01038 772 1046 9.2E-114 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS07700 fdd2ff2585dbb46911955479357b8666 708 SUPERFAMILY SSF51445 346 503 3.42E-32 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS07700 fdd2ff2585dbb46911955479357b8666 708 SUPERFAMILY SSF51445 207 306 3.42E-32 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS07700 fdd2ff2585dbb46911955479357b8666 708 Gene3D G3DSA:3.20.20.70 204 501 1.3E-34 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS07700 fdd2ff2585dbb46911955479357b8666 708 Pfam PF05691 Raffinose synthase or seed imbibition protein Sip1 176 525 1.6E-28 T 09-03-2017 IPR008811 Glycosyl hydrolases 36 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 Gene3D G3DSA:2.60.40.320 608 707 5.4E-21 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 SUPERFAMILY SSF49303 604 708 5.61E-20 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 Gene3D G3DSA:2.70.98.10 727 1009 3.8E-64 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 444 458 - T 09-03-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 Gene3D G3DSA:3.20.20.80 334 607 3.7E-83 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 SUPERFAMILY SSF74650 729 1009 1.73E-55 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 63 223 2.6E-24 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 SMART SM01038 726 1009 3.1E-51 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 Pfam PF00703 Glycosyl hydrolases family 2 225 333 8.2E-13 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 SUPERFAMILY SSF49785 36 224 2.13E-45 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 Gene3D G3DSA:2.60.40.320 213 333 4.8E-26 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 335 611 5.2E-73 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 PRINTS PR00132 Glycosyl hydrolase family 2 signature 151 166 1.7E-27 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 PRINTS PR00132 Glycosyl hydrolase family 2 signature 514 529 1.7E-27 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 PRINTS PR00132 Glycosyl hydrolase family 2 signature 375 393 1.7E-27 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 PRINTS PR00132 Glycosyl hydrolase family 2 signature 444 459 1.7E-27 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 PRINTS PR00132 Glycosyl hydrolase family 2 signature 344 358 1.7E-27 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 SUPERFAMILY SSF49303 225 333 9.21E-17 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 385 410 - T 09-03-2017 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 Gene3D G3DSA:2.60.120.260 23 212 5.4E-54 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 SUPERFAMILY SSF51445 335 608 7.04E-70 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 Pfam PF16353 Domain of unknown function(DUF4981) 622 706 9.2E-16 T 09-03-2017 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS01740 0f65d7abcbec93c715c45325890f5465 1013 Pfam PF02929 Beta galactosidase small chain 728 1008 9.8E-56 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS06165 4594fada9d34cf35b7ff71764146cf5b 86 Gene3D G3DSA:2.40.50.140 7 83 1.1E-28 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS06165 4594fada9d34cf35b7ff71764146cf5b 86 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 77 7.0E-17 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06165 4594fada9d34cf35b7ff71764146cf5b 86 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 77 4.4E-28 T 09-03-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06165 4594fada9d34cf35b7ff71764146cf5b 86 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 1 82 20.734 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06165 4594fada9d34cf35b7ff71764146cf5b 86 ProSitePatterns PS00056 Ribosomal protein S17 signature. 57 69 - T 09-03-2017 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06165 4594fada9d34cf35b7ff71764146cf5b 86 Pfam PF00366 Ribosomal protein S17 11 77 2.5E-27 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06165 4594fada9d34cf35b7ff71764146cf5b 86 SUPERFAMILY SSF50249 7 84 9.42E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS06165 4594fada9d34cf35b7ff71764146cf5b 86 PRINTS PR00973 Ribosomal protein S17 family signature 25 48 6.0E-12 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06165 4594fada9d34cf35b7ff71764146cf5b 86 PRINTS PR00973 Ribosomal protein S17 family signature 67 74 6.0E-12 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06165 4594fada9d34cf35b7ff71764146cf5b 86 PRINTS PR00973 Ribosomal protein S17 family signature 57 67 6.0E-12 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS11360 98d3710c063b13f6cec2dc50789a25c5 431 SMART SM00984 314 416 1.2E-40 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS11360 98d3710c063b13f6cec2dc50789a25c5 431 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 179 1.9E-62 T 09-03-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS11360 98d3710c063b13f6cec2dc50789a25c5 431 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 412 7.4E-131 T 09-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS11360 98d3710c063b13f6cec2dc50789a25c5 431 SUPERFAMILY SSF48179 199 293 5.44E-29 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP3_RS11360 98d3710c063b13f6cec2dc50789a25c5 431 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 415 1.2E-28 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS11360 98d3710c063b13f6cec2dc50789a25c5 431 SUPERFAMILY SSF52413 312 426 1.7E-30 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS11360 98d3710c063b13f6cec2dc50789a25c5 431 SUPERFAMILY SSF51735 2 189 9.28E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS11360 98d3710c063b13f6cec2dc50789a25c5 431 Gene3D G3DSA:3.40.50.720 230 431 3.3E-66 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS11360 98d3710c063b13f6cec2dc50789a25c5 431 Gene3D G3DSA:3.40.50.720 2 202 3.7E-72 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS11360 98d3710c063b13f6cec2dc50789a25c5 431 Gene3D G3DSA:1.20.5.100 203 228 5.6E-17 T 09-03-2017 L21SP3_RS11360 98d3710c063b13f6cec2dc50789a25c5 431 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 200 290 9.4E-35 T 09-03-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS11360 98d3710c063b13f6cec2dc50789a25c5 431 PIRSF PIRSF000124 1 431 3.7E-139 T 09-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS11360 98d3710c063b13f6cec2dc50789a25c5 431 PIRSF PIRSF500134 1 431 2.5E-170 T 09-03-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 L21SP3_RS03715 30dfafe3c0562235632f2d1997d90b23 465 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 218 250 1.5E-4 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS03715 30dfafe3c0562235632f2d1997d90b23 465 SUPERFAMILY SSF53448 219 275 5.09E-14 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS03715 30dfafe3c0562235632f2d1997d90b23 465 SUPERFAMILY SSF53448 27 186 5.09E-14 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS03715 30dfafe3c0562235632f2d1997d90b23 465 Gene3D G3DSA:3.90.550.10 27 125 1.9E-8 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS03715 30dfafe3c0562235632f2d1997d90b23 465 Gene3D G3DSA:2.160.10.10 194 279 5.1E-13 T 09-03-2017 L21SP3_RS03715 30dfafe3c0562235632f2d1997d90b23 465 Pfam PF02397 Bacterial sugar transferase 316 458 3.0E-6 T 09-03-2017 IPR003362 Bacterial sugar transferase L21SP3_RS03715 30dfafe3c0562235632f2d1997d90b23 465 SUPERFAMILY SSF51161 189 273 7.9E-15 T 09-03-2017 IPR011004 Trimeric LpxA-like L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 Gene3D G3DSA:2.70.98.10 872 972 5.2E-6 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 Gene3D G3DSA:2.60.120.260 44 181 2.8E-39 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 SUPERFAMILY SSF74650 874 983 1.88E-9 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 59 190 4.6E-22 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 PRINTS PR00132 Glycosyl hydrolase family 2 signature 334 352 4.0E-8 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 PRINTS PR00132 Glycosyl hydrolase family 2 signature 303 317 4.0E-8 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 Pfam PF02929 Beta galactosidase small chain 687 973 1.3E-6 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 294 518 1.1E-33 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 SUPERFAMILY SSF49785 23 191 1.01E-38 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 SUPERFAMILY SSF51445 294 550 5.16E-57 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 SUPERFAMILY SSF49303 202 292 6.04E-11 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 SUPERFAMILY SSF49303 552 632 2.37E-5 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 Pfam PF00703 Glycosyl hydrolases family 2 203 292 1.2E-10 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 Gene3D G3DSA:3.20.20.80 291 553 1.3E-57 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 Gene3D G3DSA:2.60.40.320 561 635 1.2E-7 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS00820 757d3ce9c447ab47e66ae627d44f9b99 1050 Gene3D G3DSA:2.60.40.320 182 290 1.1E-19 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS00970 392c4a5d3ec80bceffcb7eafcff9c387 171 Gene3D G3DSA:3.30.1330.50 8 165 3.3E-61 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 L21SP3_RS00970 392c4a5d3ec80bceffcb7eafcff9c387 171 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 11 164 6.9E-55 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 L21SP3_RS00970 392c4a5d3ec80bceffcb7eafcff9c387 171 SUPERFAMILY SSF69765 9 165 1.03E-56 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 L21SP3_RS00970 392c4a5d3ec80bceffcb7eafcff9c387 171 Pfam PF02542 YgbB family 11 163 4.9E-59 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 L21SP3_RS00970 392c4a5d3ec80bceffcb7eafcff9c387 171 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 10 165 31.615 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 L21SP3_RS00970 392c4a5d3ec80bceffcb7eafcff9c387 171 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 44 59 - T 09-03-2017 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 Gene3D G3DSA:1.10.150.20 499 578 5.2E-27 T 09-03-2017 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 SUPERFAMILY SSF50249 313 395 2.91E-25 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 Gene3D G3DSA:1.10.287.610 3 66 1.1E-26 T 09-03-2017 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 Hamap MF_01588 DNA ligase [ligA]. 1 660 51.177 T 09-03-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 SUPERFAMILY SSF52113 584 659 1.22E-19 T 09-03-2017 IPR001357 BRCT domain L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 Pfam PF14520 Helix-hairpin-helix domain 445 495 7.5E-5 T 09-03-2017 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 113 142 - T 09-03-2017 IPR018239 NAD-dependent DNA ligase, active site L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 3 314 2.5E-120 T 09-03-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 Pfam PF12826 Helix-hairpin-helix motif 505 568 1.3E-20 T 09-03-2017 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 SMART SM00278 539 558 240.0 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 SMART SM00278 475 494 0.32 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 SMART SM00292 586 660 9.1E-14 T 09-03-2017 IPR001357 BRCT domain L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 SUPERFAMILY SSF56091 2 311 2.24E-112 T 09-03-2017 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 PIRSF PIRSF001604 1 661 3.6E-251 T 09-03-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 Gene3D G3DSA:2.40.50.140 316 386 4.0E-31 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 327 342 - T 09-03-2017 IPR033136 NAD-dependent DNA ligase, conserved site L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 Gene3D G3DSA:3.30.470.30 117 248 3.7E-46 T 09-03-2017 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 SUPERFAMILY SSF47781 401 577 8.9E-56 T 09-03-2017 IPR010994 RuvA domain 2-like L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 586 658 3.0E-17 T 09-03-2017 IPR001357 BRCT domain L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 10 656 1.7E-247 T 09-03-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 SMART SM00532 2 443 1.1E-230 T 09-03-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 Gene3D G3DSA:3.40.50.10190 584 660 5.3E-26 T 09-03-2017 IPR001357 BRCT domain L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 317 394 3.8E-33 T 09-03-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 Gene3D G3DSA:1.10.150.20 430 498 6.6E-24 T 09-03-2017 L21SP3_RS05260 8627d2daa8f4aff9932094c7f3aa73db 661 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 403 429 3.7E-7 T 09-03-2017 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 Gene3D G3DSA:3.40.50.1260 1 188 1.3E-70 T 09-03-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 Gene3D G3DSA:3.40.50.1270 195 399 1.4E-80 T 09-03-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 SUPERFAMILY SSF53748 1 411 3.06E-148 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 Pfam PF00162 Phosphoglycerate kinase 6 401 1.2E-153 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 PIRSF PIRSF000724 1 412 1.1E-142 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 411 39.892 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 PRINTS PR00477 Phosphoglycerate kinase family signature 364 375 8.1E-87 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 8.1E-87 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 PRINTS PR00477 Phosphoglycerate kinase family signature 151 173 8.1E-87 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 PRINTS PR00477 Phosphoglycerate kinase family signature 207 226 8.1E-87 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 PRINTS PR00477 Phosphoglycerate kinase family signature 184 206 8.1E-87 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 PRINTS PR00477 Phosphoglycerate kinase family signature 328 353 8.1E-87 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 8.1E-87 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 8.1E-87 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 PRINTS PR00477 Phosphoglycerate kinase family signature 387 404 8.1E-87 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02760 552a5aa784c78d20be14129d6d0210f4 412 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 09-03-2017 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS03825 8a4be04e3a43b772313d52e76d1d56aa 344 SUPERFAMILY SSF52540 25 275 1.55E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03825 8a4be04e3a43b772313d52e76d1d56aa 344 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 255 320 1.1E-18 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 L21SP3_RS03825 8a4be04e3a43b772313d52e76d1d56aa 344 ProSitePatterns PS00211 ABC transporters family signature. 176 190 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS03825 8a4be04e3a43b772313d52e76d1d56aa 344 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 253 342 4.8E-27 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 L21SP3_RS03825 8a4be04e3a43b772313d52e76d1d56aa 344 Gene3D G3DSA:3.40.50.300 21 279 9.2E-80 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03825 8a4be04e3a43b772313d52e76d1d56aa 344 SMART SM00382 61 253 2.5E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS03825 8a4be04e3a43b772313d52e76d1d56aa 344 Pfam PF00005 ABC transporter 53 203 1.0E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS08720 6c5825cce00246881cdde0b14db6b7d9 432 SUPERFAMILY SSF53649 2 391 3.93E-38 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS08720 6c5825cce00246881cdde0b14db6b7d9 432 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 6 372 1.4E-43 T 09-03-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 L21SP3_RS08720 6c5825cce00246881cdde0b14db6b7d9 432 Gene3D G3DSA:3.40.720.10 4 309 1.1E-40 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS05700 0a332566c834d0f556785faf2c930139 88 Gene3D G3DSA:3.30.70.20 5 77 3.5E-11 T 09-03-2017 L21SP3_RS05700 0a332566c834d0f556785faf2c930139 88 Pfam PF12838 4Fe-4S dicluster domain 18 65 3.4E-7 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS05700 0a332566c834d0f556785faf2c930139 88 SUPERFAMILY SSF54862 9 72 9.3E-11 T 09-03-2017 L21SP3_RS09510 8917797c3752c048325d04ab0623a392 343 SUPERFAMILY SSF52980 201 315 2.28E-14 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 L21SP3_RS09510 8917797c3752c048325d04ab0623a392 343 Pfam PF04471 Restriction endonuclease 198 311 9.3E-22 T 09-03-2017 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 L21SP3_RS09510 8917797c3752c048325d04ab0623a392 343 PIRSF PIRSF031853 1 338 6.3E-108 T 09-03-2017 IPR016984 Uncharacterised conserved protein UCP031853 L21SP3_RS09510 8917797c3752c048325d04ab0623a392 343 Gene3D G3DSA:3.40.1350.10 199 305 1.4E-11 T 09-03-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 L21SP3_RS05970 ca99ed4529d46a7c2a80216731f3c693 565 SMART SM00382 315 467 0.0034 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS05970 ca99ed4529d46a7c2a80216731f3c693 565 SUPERFAMILY SSF160246 10 141 3.27E-16 T 09-03-2017 L21SP3_RS05970 ca99ed4529d46a7c2a80216731f3c693 565 Pfam PF00437 Type II/IV secretion system protein 191 454 2.5E-78 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS05970 ca99ed4529d46a7c2a80216731f3c693 565 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 77 560 7.3E-193 T 09-03-2017 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 L21SP3_RS05970 ca99ed4529d46a7c2a80216731f3c693 565 SUPERFAMILY SSF52540 171 560 5.74E-101 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05970 ca99ed4529d46a7c2a80216731f3c693 565 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 45 145 1.7E-8 T 09-03-2017 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 L21SP3_RS05970 ca99ed4529d46a7c2a80216731f3c693 565 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 382 396 - T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS05970 ca99ed4529d46a7c2a80216731f3c693 565 Gene3D G3DSA:3.40.50.300 292 561 1.1E-98 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05970 ca99ed4529d46a7c2a80216731f3c693 565 Gene3D G3DSA:3.30.450.90 157 287 1.3E-47 T 09-03-2017 L21SP3_RS02025 7503fe3a2e7c2741ef843fbf6e5c1ea1 740 Gene3D G3DSA:3.40.718.10 168 280 1.7E-32 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 L21SP3_RS02025 7503fe3a2e7c2741ef843fbf6e5c1ea1 740 Gene3D G3DSA:3.40.718.10 538 646 1.7E-32 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 L21SP3_RS02025 7503fe3a2e7c2741ef843fbf6e5c1ea1 740 Gene3D G3DSA:3.40.718.10 339 362 1.7E-32 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 L21SP3_RS02025 7503fe3a2e7c2741ef843fbf6e5c1ea1 740 Pfam PF03971 Monomeric isocitrate dehydrogenase 3 738 0.0 T 09-03-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 L21SP3_RS02025 7503fe3a2e7c2741ef843fbf6e5c1ea1 740 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 2 739 0.0 T 09-03-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 L21SP3_RS02025 7503fe3a2e7c2741ef843fbf6e5c1ea1 740 PIRSF PIRSF009407 1 740 0.0 T 09-03-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 L21SP3_RS02025 7503fe3a2e7c2741ef843fbf6e5c1ea1 740 SUPERFAMILY SSF53659 3 738 0.0 T 09-03-2017 L21SP3_RS11570 4ea260146067d7eb75a1a6d2626f1d84 128 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 7 103 1.6E-20 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 L21SP3_RS11570 4ea260146067d7eb75a1a6d2626f1d84 128 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 120 1.0E-18 T 09-03-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 L21SP3_RS11570 4ea260146067d7eb75a1a6d2626f1d84 128 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 7 121 5.8E-27 T 09-03-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 L21SP3_RS11570 4ea260146067d7eb75a1a6d2626f1d84 128 SUPERFAMILY SSF56214 7 122 1.7E-26 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 L21SP3_RS11570 4ea260146067d7eb75a1a6d2626f1d84 128 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 7 120 1.4E-23 T 09-03-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 L21SP3_RS11570 4ea260146067d7eb75a1a6d2626f1d84 128 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 126 22.11 T 09-03-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 L21SP3_RS11570 4ea260146067d7eb75a1a6d2626f1d84 128 Gene3D G3DSA:3.90.470.20 6 122 6.8E-36 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 L21SP3_RS05475 dea06a64926eb6af4fbcaf843b81ab51 295 SUPERFAMILY SSF54523 8 87 5.1E-16 T 09-03-2017 L21SP3_RS05475 dea06a64926eb6af4fbcaf843b81ab51 295 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 4 27 5.5E-9 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS05475 dea06a64926eb6af4fbcaf843b81ab51 295 PRINTS PR00813 Bacterial general secretion pathway protein G signature 7 32 6.7E-7 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS05475 dea06a64926eb6af4fbcaf843b81ab51 295 PRINTS PR00813 Bacterial general secretion pathway protein G signature 43 61 6.7E-7 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS05475 dea06a64926eb6af4fbcaf843b81ab51 295 Pfam PF07596 Protein of unknown function (DUF1559) 33 67 2.9E-5 T 09-03-2017 IPR011453 Protein of unknown function DUF1559 L21SP3_RS05475 dea06a64926eb6af4fbcaf843b81ab51 295 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS05475 dea06a64926eb6af4fbcaf843b81ab51 295 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 4.6E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS05475 dea06a64926eb6af4fbcaf843b81ab51 295 Gene3D G3DSA:3.30.700.10 8 62 1.1E-5 T 09-03-2017 L21SP3_RS00205 24d881a1d560df7400bb41e406be913b 246 Pfam PF00849 RNA pseudouridylate synthase 65 195 4.2E-22 T 09-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS00205 24d881a1d560df7400bb41e406be913b 246 Pfam PF01479 S4 domain 4 38 1.9E-8 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS00205 24d881a1d560df7400bb41e406be913b 246 SUPERFAMILY SSF55120 50 233 7.84E-41 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS00205 24d881a1d560df7400bb41e406be913b 246 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 101 115 - T 09-03-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 L21SP3_RS00205 24d881a1d560df7400bb41e406be913b 246 SMART SM00363 4 83 2.4E-5 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS00205 24d881a1d560df7400bb41e406be913b 246 SUPERFAMILY SSF55174 3 70 1.39E-11 T 09-03-2017 L21SP3_RS00205 24d881a1d560df7400bb41e406be913b 246 Gene3D G3DSA:3.10.290.10 3 67 4.6E-18 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS00205 24d881a1d560df7400bb41e406be913b 246 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 69 226 1.7E-46 T 09-03-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 L21SP3_RS09805 6c833db24f38cefab4190baf226ebab6 596 Gene3D G3DSA:3.40.1360.10 246 367 8.8E-38 T 09-03-2017 L21SP3_RS09805 6c833db24f38cefab4190baf226ebab6 596 TIGRFAM TIGR01391 dnaG: DNA primase 6 404 4.4E-116 T 09-03-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 L21SP3_RS09805 6c833db24f38cefab4190baf226ebab6 596 SUPERFAMILY SSF57783 7 101 8.33E-28 T 09-03-2017 L21SP3_RS09805 6c833db24f38cefab4190baf226ebab6 596 SMART SM00493 264 335 1.1E-16 T 09-03-2017 IPR006171 Toprim domain L21SP3_RS09805 6c833db24f38cefab4190baf226ebab6 596 PIRSF PIRSF002811 2 595 3.7E-145 T 09-03-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 L21SP3_RS09805 6c833db24f38cefab4190baf226ebab6 596 Pfam PF01807 CHC2 zinc finger 8 102 1.3E-27 T 09-03-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 L21SP3_RS09805 6c833db24f38cefab4190baf226ebab6 596 Pfam PF08275 DNA primase catalytic core, N-terminal domain 137 257 5.4E-37 T 09-03-2017 IPR013264 DNA primase, catalytic core, N-terminal L21SP3_RS09805 6c833db24f38cefab4190baf226ebab6 596 Pfam PF13155 Toprim-like 267 352 1.0E-14 T 09-03-2017 L21SP3_RS09805 6c833db24f38cefab4190baf226ebab6 596 SMART SM00400 38 92 1.9E-22 T 09-03-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 L21SP3_RS09805 6c833db24f38cefab4190baf226ebab6 596 SUPERFAMILY SSF56731 120 403 8.89E-86 T 09-03-2017 L21SP3_RS09805 6c833db24f38cefab4190baf226ebab6 596 Gene3D G3DSA:3.90.980.10 119 245 8.6E-38 T 09-03-2017 IPR013264 DNA primase, catalytic core, N-terminal L21SP3_RS09805 6c833db24f38cefab4190baf226ebab6 596 Gene3D G3DSA:3.90.580.10 5 103 8.4E-31 T 09-03-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 L21SP3_RS09805 6c833db24f38cefab4190baf226ebab6 596 Hamap MF_00974 DNA primase [dnaG]. 4 576 24.367 T 09-03-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 L21SP3_RS03160 a53a649224bc1fa4d1210ef8832a4769 717 SMART SM00409 375 457 9.6E-5 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS03160 a53a649224bc1fa4d1210ef8832a4769 717 Gene3D G3DSA:2.60.120.200 458 672 9.3E-31 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03160 a53a649224bc1fa4d1210ef8832a4769 717 Pfam PF13927 Immunoglobulin domain 369 441 1.1E-9 T 09-03-2017 L21SP3_RS03160 a53a649224bc1fa4d1210ef8832a4769 717 SUPERFAMILY SSF48726 368 448 1.24E-9 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS03160 a53a649224bc1fa4d1210ef8832a4769 717 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 518 669 4.7E-22 T 09-03-2017 L21SP3_RS03160 a53a649224bc1fa4d1210ef8832a4769 717 Gene3D G3DSA:2.60.40.10 369 457 1.0E-9 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS03160 a53a649224bc1fa4d1210ef8832a4769 717 SUPERFAMILY SSF49899 456 673 2.05E-28 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS08460 ea01836004938cba5cb8ee0b073229c5 522 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 184 190 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 L21SP3_RS08460 ea01836004938cba5cb8ee0b073229c5 522 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 49 63 1.4E-8 T 09-03-2017 L21SP3_RS08460 ea01836004938cba5cb8ee0b073229c5 522 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 181 193 1.4E-8 T 09-03-2017 L21SP3_RS08460 ea01836004938cba5cb8ee0b073229c5 522 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 21 37 1.4E-8 T 09-03-2017 L21SP3_RS08460 ea01836004938cba5cb8ee0b073229c5 522 Gene3D G3DSA:3.40.50.150 174 269 1.0E-18 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08460 ea01836004938cba5cb8ee0b073229c5 522 Gene3D G3DSA:3.40.50.150 23 136 1.0E-18 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08460 ea01836004938cba5cb8ee0b073229c5 522 SUPERFAMILY SSF53335 173 274 2.13E-25 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08460 ea01836004938cba5cb8ee0b073229c5 522 SUPERFAMILY SSF53335 19 138 2.13E-25 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08460 ea01836004938cba5cb8ee0b073229c5 522 Pfam PF07669 Eco57I restriction-modification methylase 179 277 8.7E-35 T 09-03-2017 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 L21SP3_RS10800 01eb0a27d59d51f2a10bf2d466d751a6 121 PRINTS PR01034 Ribosomal protein S12 signature 93 109 3.5E-55 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS10800 01eb0a27d59d51f2a10bf2d466d751a6 121 PRINTS PR01034 Ribosomal protein S12 signature 41 56 3.5E-55 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS10800 01eb0a27d59d51f2a10bf2d466d751a6 121 PRINTS PR01034 Ribosomal protein S12 signature 57 76 3.5E-55 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS10800 01eb0a27d59d51f2a10bf2d466d751a6 121 PRINTS PR01034 Ribosomal protein S12 signature 76 93 3.5E-55 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS10800 01eb0a27d59d51f2a10bf2d466d751a6 121 PRINTS PR01034 Ribosomal protein S12 signature 26 41 3.5E-55 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS10800 01eb0a27d59d51f2a10bf2d466d751a6 121 PRINTS PR01034 Ribosomal protein S12 signature 109 121 3.5E-55 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS10800 01eb0a27d59d51f2a10bf2d466d751a6 121 ProSitePatterns PS00055 Ribosomal protein S12 signature. 42 49 - T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS10800 01eb0a27d59d51f2a10bf2d466d751a6 121 PIRSF PIRSF002133 1 121 1.5E-52 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS10800 01eb0a27d59d51f2a10bf2d466d751a6 121 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 121 35.956 T 09-03-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS10800 01eb0a27d59d51f2a10bf2d466d751a6 121 Gene3D G3DSA:2.40.50.140 1 120 3.4E-59 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS10800 01eb0a27d59d51f2a10bf2d466d751a6 121 SUPERFAMILY SSF50249 3 120 1.11E-47 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS10800 01eb0a27d59d51f2a10bf2d466d751a6 121 Pfam PF00164 Ribosomal protein S12/S23 10 120 9.4E-39 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS10800 01eb0a27d59d51f2a10bf2d466d751a6 121 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 120 6.5E-61 T 09-03-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 Gene3D G3DSA:3.20.20.120 129 429 1.6E-138 T 09-03-2017 IPR029065 Enolase C-terminal domain-like L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 Pfam PF00113 Enolase, C-terminal TIM barrel domain 142 423 1.5E-130 T 09-03-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 Pfam PF03952 Enolase, N-terminal domain 5 135 1.7E-61 T 09-03-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 SUPERFAMILY SSF54826 4 139 3.68E-59 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 Gene3D G3DSA:3.30.390.10 4 126 9.5E-58 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 PIRSF PIRSF001400 1 429 6.0E-195 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 PRINTS PR00148 Enolase signature 339 353 8.4E-46 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 PRINTS PR00148 Enolase signature 368 385 8.4E-46 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 PRINTS PR00148 Enolase signature 316 327 8.4E-46 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 PRINTS PR00148 Enolase signature 38 52 8.4E-46 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 PRINTS PR00148 Enolase signature 108 124 8.4E-46 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 PRINTS PR00148 Enolase signature 162 175 8.4E-46 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 SUPERFAMILY SSF51604 140 424 3.68E-128 T 09-03-2017 IPR029065 Enolase C-terminal domain-like L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 5 424 2.5E-210 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 ProSitePatterns PS00164 Enolase signature. 339 352 - T 09-03-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 Hamap MF_00318 Enolase [eno]. 3 416 44.958 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 SMART SM01193 5 135 3.5E-97 T 09-03-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS02785 7918758598edc432b717012e47955ed2 431 SMART SM01192 140 430 7.4E-218 T 09-03-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 SUPERFAMILY SSF46689 406 496 4.48E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 SMART SM00382 213 360 5.7E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 SUPERFAMILY SSF55785 57 161 2.79E-19 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 54 176 5.7E-16 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 Gene3D G3DSA:1.10.8.60 366 438 1.9E-20 T 09-03-2017 L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 Gene3D G3DSA:3.40.50.300 190 364 7.6E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 SUPERFAMILY SSF52540 193 437 1.49E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 Pfam PF13426 PAS domain 63 168 1.0E-16 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 406 415 - T 09-03-2017 IPR025944 Sigma-54 interaction domain, conserved site L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 SMART SM00091 53 121 3.2E-5 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 459 476 2.1E-12 T 09-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 476 496 2.1E-12 T 09-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 Pfam PF00158 Sigma-54 interaction domain 193 359 9.2E-68 T 09-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 Gene3D G3DSA:1.10.10.60 458 496 4.0E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 217 230 - T 09-03-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 Gene3D G3DSA:3.30.450.20 56 168 1.5E-22 T 09-03-2017 L21SP3_RS10370 f30608e325f7c9cebc84375cbe5de95e 498 Pfam PF02954 Bacterial regulatory protein, Fis family 459 493 6.8E-12 T 09-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP3_RS07650 fedb7ea40d493d07d3be55a955fbb5c5 61 SUPERFAMILY SSF158446 19 56 8.11E-6 T 09-03-2017 L21SP3_RS07650 fedb7ea40d493d07d3be55a955fbb5c5 61 TIGRFAM TIGR02436 TIGR02436: four helix bundle protein 19 56 3.8E-6 T 09-03-2017 IPR012657 23S rRNA-intervening sequence protein L21SP3_RS07650 fedb7ea40d493d07d3be55a955fbb5c5 61 Gene3D G3DSA:1.20.1440.60 19 56 1.1E-6 T 09-03-2017 IPR012657 23S rRNA-intervening sequence protein L21SP3_RS00695 c9942989861eb48205f1f29932bb6ea2 328 Pfam PF01595 Domain of unknown function DUF21 7 139 1.4E-32 T 09-03-2017 IPR002550 Domain of unknown function DUF21 L21SP3_RS00695 c9942989861eb48205f1f29932bb6ea2 328 Pfam PF00571 CBS domain 202 257 0.0057 T 09-03-2017 IPR000644 CBS domain L21SP3_RS00695 c9942989861eb48205f1f29932bb6ea2 328 Pfam PF00571 CBS domain 272 321 0.002 T 09-03-2017 IPR000644 CBS domain L21SP3_RS00695 c9942989861eb48205f1f29932bb6ea2 328 Gene3D G3DSA:3.10.580.10 189 326 1.2E-13 T 09-03-2017 L21SP3_RS00695 c9942989861eb48205f1f29932bb6ea2 328 SUPERFAMILY SSF54631 192 325 2.51E-17 T 09-03-2017 L21SP3_RS04590 630d01cc93345a906839fb79b50f0989 281 Pfam PF13633 Prokaryotic N-terminal methylation site 9 33 3.2E-6 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS04590 630d01cc93345a906839fb79b50f0989 281 SUPERFAMILY SSF54523 10 91 2.51E-15 T 09-03-2017 L21SP3_RS04590 630d01cc93345a906839fb79b50f0989 281 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 29 7.3E-5 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS04590 630d01cc93345a906839fb79b50f0989 281 Gene3D G3DSA:3.30.700.10 10 65 9.5E-8 T 09-03-2017 L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 409 631 1.1E-40 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 40 372 4.6E-70 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 PRINTS PR00133 Glycosyl hydrolase family 3 signature 136 155 7.2E-17 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 PRINTS PR00133 Glycosyl hydrolase family 3 signature 220 236 7.2E-17 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 PRINTS PR00133 Glycosyl hydrolase family 3 signature 182 198 7.2E-17 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 PRINTS PR00133 Glycosyl hydrolase family 3 signature 290 308 7.2E-17 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 PRINTS PR00133 Glycosyl hydrolase family 3 signature 112 128 7.2E-17 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 SUPERFAMILY SSF52279 409 634 8.11E-46 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 SMART SM01217 670 739 2.8E-25 T 09-03-2017 IPR026891 Fibronectin type III-like domain L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 Pfam PF14310 Fibronectin type III-like domain 671 736 8.1E-19 T 09-03-2017 IPR026891 Fibronectin type III-like domain L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 Gene3D G3DSA:3.40.50.1700 395 634 2.2E-58 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 SUPERFAMILY SSF51445 26 407 2.53E-99 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 290 307 - T 09-03-2017 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 L21SP3_RS00095 ffbd91897bad908a146a5d134418eb3e 745 Gene3D G3DSA:3.20.20.300 26 389 6.9E-109 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS11575 dc83164ee78045747cbd1c0c3e99e603 361 SUPERFAMILY SSF54534 205 297 2.03E-10 T 09-03-2017 L21SP3_RS11575 dc83164ee78045747cbd1c0c3e99e603 361 Gene3D G3DSA:3.10.50.40 196 321 1.7E-16 T 09-03-2017 L21SP3_RS11575 dc83164ee78045747cbd1c0c3e99e603 361 SUPERFAMILY SSF109998 79 221 4.71E-13 T 09-03-2017 IPR027304 Trigger factor/SurA domain L21SP3_RS11575 dc83164ee78045747cbd1c0c3e99e603 361 Pfam PF13145 PPIC-type PPIASE domain 184 311 3.6E-12 T 09-03-2017 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 L21SP3_RS07805 f81b46a8cbfe408aa2fd7ac2ab31ba15 621 Gene3D G3DSA:3.40.930.10 489 611 4.1E-26 T 09-03-2017 IPR002178 PTS EIIA type-2 domain L21SP3_RS07805 f81b46a8cbfe408aa2fd7ac2ab31ba15 621 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 489 611 1.2E-23 T 09-03-2017 IPR002178 PTS EIIA type-2 domain L21SP3_RS07805 f81b46a8cbfe408aa2fd7ac2ab31ba15 621 Pfam PF13520 Amino acid permease 8 410 3.8E-49 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 L21SP3_RS07805 f81b46a8cbfe408aa2fd7ac2ab31ba15 621 SUPERFAMILY SSF55804 486 611 3.27E-23 T 09-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 L21SP3_RS05045 bf9f6b9bae7e0e27bd045d53999a2255 299 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 67 81 1.0E-29 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS05045 bf9f6b9bae7e0e27bd045d53999a2255 299 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 242 260 1.0E-29 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS05045 bf9f6b9bae7e0e27bd045d53999a2255 299 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 99 119 1.0E-29 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS05045 bf9f6b9bae7e0e27bd045d53999a2255 299 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 223 240 1.0E-29 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS05045 bf9f6b9bae7e0e27bd045d53999a2255 299 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 265 285 1.0E-29 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS05045 bf9f6b9bae7e0e27bd045d53999a2255 299 SUPERFAMILY SSF53335 47 285 1.09E-62 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS05045 bf9f6b9bae7e0e27bd045d53999a2255 299 Pfam PF01555 DNA methylase 69 279 5.1E-47 T 09-03-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 L21SP3_RS05045 bf9f6b9bae7e0e27bd045d53999a2255 299 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 72 77 - T 09-03-2017 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 L21SP3_RS05045 bf9f6b9bae7e0e27bd045d53999a2255 299 Gene3D G3DSA:3.40.50.150 48 292 7.1E-66 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 Pfam PF00342 Phosphoglucose isomerase 52 541 1.2E-249 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 SUPERFAMILY SSF53697 6 545 1.67E-223 T 09-03-2017 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 Gene3D G3DSA:3.40.50.10490 99 290 7.2E-89 T 09-03-2017 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 497 7.7E-55 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 150 169 7.7E-55 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 497 510 7.7E-55 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 465 483 7.7E-55 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 261 279 7.7E-55 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 338 359 7.7E-55 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 497 514 - T 09-03-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 46 524 41.853 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 265 278 - T 09-03-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 Gene3D G3DSA:3.40.50.10490 293 506 4.4E-150 T 09-03-2017 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 Gene3D G3DSA:3.40.50.10490 10 98 4.4E-150 T 09-03-2017 L21SP3_RS05055 26cb259e465d1b0bea488aadf3723e1a 548 Gene3D G3DSA:1.10.1390.10 507 547 1.2E-21 T 09-03-2017 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS06315 30a9a3bc03bd40b680528ccc141a83ff 378 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 196 210 - T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS06315 30a9a3bc03bd40b680528ccc141a83ff 378 Pfam PF00437 Type II/IV secretion system protein 19 265 1.1E-40 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS06315 30a9a3bc03bd40b680528ccc141a83ff 378 Gene3D G3DSA:3.40.50.300 103 345 1.8E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06315 30a9a3bc03bd40b680528ccc141a83ff 378 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 6 347 8.6E-133 T 09-03-2017 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 L21SP3_RS06315 30a9a3bc03bd40b680528ccc141a83ff 378 SUPERFAMILY SSF52540 6 339 1.74E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06315 30a9a3bc03bd40b680528ccc141a83ff 378 SMART SM00382 125 259 0.0041 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS06580 4be08fc09d1ca230201d6e8ea5338ce9 104 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 97 8.4E-17 T 09-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 L21SP3_RS06580 4be08fc09d1ca230201d6e8ea5338ce9 104 Gene3D G3DSA:3.30.160.100 1 98 9.6E-18 T 09-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 L21SP3_RS06580 4be08fc09d1ca230201d6e8ea5338ce9 104 SUPERFAMILY SSF69754 2 102 1.01E-17 T 09-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 L21SP3_RS06580 4be08fc09d1ca230201d6e8ea5338ce9 104 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 99 3.0E-16 T 09-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 L21SP3_RS01760 abe184f3c1ff0c8befdcbe422d8c4f26 405 Gene3D G3DSA:3.20.20.100 48 318 7.6E-37 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain L21SP3_RS01760 abe184f3c1ff0c8befdcbe422d8c4f26 405 Pfam PF00248 Aldo/keto reductase family 81 315 1.5E-21 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain L21SP3_RS01760 abe184f3c1ff0c8befdcbe422d8c4f26 405 SUPERFAMILY SSF51430 48 318 3.54E-35 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain L21SP3_RS01760 abe184f3c1ff0c8befdcbe422d8c4f26 405 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 21 5.0E-4 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal L21SP3_RS01335 694f5eded68a37d349d08e2c0b0d7fab 666 Gene3D G3DSA:2.60.120.200 516 664 5.0E-10 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS01335 694f5eded68a37d349d08e2c0b0d7fab 666 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 549 664 5.2E-10 T 09-03-2017 L21SP3_RS01335 694f5eded68a37d349d08e2c0b0d7fab 666 SUPERFAMILY SSF53649 37 475 9.89E-117 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS01335 694f5eded68a37d349d08e2c0b0d7fab 666 Gene3D G3DSA:3.30.1120.10 389 478 3.5E-19 T 09-03-2017 L21SP3_RS01335 694f5eded68a37d349d08e2c0b0d7fab 666 Gene3D G3DSA:3.40.720.10 36 387 8.0E-94 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS01335 694f5eded68a37d349d08e2c0b0d7fab 666 SUPERFAMILY SSF49899 537 664 3.76E-12 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS01335 694f5eded68a37d349d08e2c0b0d7fab 666 ProSitePatterns PS00149 Sulfatases signature 2. 138 148 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS01335 694f5eded68a37d349d08e2c0b0d7fab 666 Pfam PF00884 Sulfatase 38 367 2.3E-59 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS00740 ec2c844df492a8e950721260132685ff 424 SUPERFAMILY SSF46689 318 368 2.45E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS00740 ec2c844df492a8e950721260132685ff 424 SUPERFAMILY SSF46689 371 418 5.82E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS00740 ec2c844df492a8e950721260132685ff 424 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 386 401 3.0E-6 T 09-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP3_RS00740 ec2c844df492a8e950721260132685ff 424 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 401 417 3.0E-6 T 09-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP3_RS00740 ec2c844df492a8e950721260132685ff 424 Gene3D G3DSA:1.10.10.60 371 418 3.8E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS00740 ec2c844df492a8e950721260132685ff 424 Gene3D G3DSA:1.10.10.60 314 370 8.7E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS00740 ec2c844df492a8e950721260132685ff 424 SMART SM00342 334 417 7.1E-35 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS00740 ec2c844df492a8e950721260132685ff 424 Pfam PF12833 Helix-turn-helix domain 340 417 1.1E-23 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS00740 ec2c844df492a8e950721260132685ff 424 Pfam PF10114 Sensory domain found in PocR 9 165 1.4E-21 T 09-03-2017 IPR018771 PocR domain L21SP3_RS11745 99db9a68476d6fb71d41fcaa6c10ad20 406 Pfam PF14294 Domain of unknown function (DUF4372) 7 73 1.4E-14 T 09-03-2017 IPR025399 Domain of unknown function DUF4372 L21SP3_RS11745 99db9a68476d6fb71d41fcaa6c10ad20 406 Pfam PF01609 Transposase DDE domain 131 346 9.7E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS11745 99db9a68476d6fb71d41fcaa6c10ad20 406 SUPERFAMILY SSF53098 128 370 1.74E-24 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS11745 99db9a68476d6fb71d41fcaa6c10ad20 406 Gene3D G3DSA:3.90.350.10 255 322 2.9E-4 T 09-03-2017 IPR014736 Transposase, Tn5-like, core L21SP3_RS04765 bcd0c452a139c3ad0f6b53b38ec26496 185 Gene3D G3DSA:3.40.630.30 17 47 1.4E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS04765 bcd0c452a139c3ad0f6b53b38ec26496 185 Gene3D G3DSA:3.40.630.30 93 176 1.4E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS04765 bcd0c452a139c3ad0f6b53b38ec26496 185 SUPERFAMILY SSF55729 8 60 8.72E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS04765 bcd0c452a139c3ad0f6b53b38ec26496 185 SUPERFAMILY SSF55729 93 171 8.72E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS04765 bcd0c452a139c3ad0f6b53b38ec26496 185 Pfam PF00583 Acetyltransferase (GNAT) family 98 159 3.7E-8 T 09-03-2017 IPR000182 GNAT domain GO:0008080 L21SP3_RS10545 0bbbebe7974d389b6ff8ef384f021e73 373 SUPERFAMILY SSF47413 22 79 2.65E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS10545 0bbbebe7974d389b6ff8ef384f021e73 373 SUPERFAMILY SSF53822 81 343 1.13E-29 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS10545 0bbbebe7974d389b6ff8ef384f021e73 373 Gene3D G3DSA:1.10.260.40 22 76 2.3E-23 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS10545 0bbbebe7974d389b6ff8ef384f021e73 373 Pfam PF13377 Periplasmic binding protein-like domain 198 368 9.9E-18 T 09-03-2017 L21SP3_RS10545 0bbbebe7974d389b6ff8ef384f021e73 373 Pfam PF00356 Bacterial regulatory proteins, lacI family 23 71 1.9E-17 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 L21SP3_RS10545 0bbbebe7974d389b6ff8ef384f021e73 373 SMART SM00354 21 94 5.1E-24 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 L21SP3_RS10545 0bbbebe7974d389b6ff8ef384f021e73 373 Gene3D G3DSA:3.40.50.2300 77 203 1.7E-23 T 09-03-2017 L21SP3_RS10545 0bbbebe7974d389b6ff8ef384f021e73 373 Gene3D G3DSA:3.40.50.2300 204 340 2.8E-16 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 441 9.5E-36 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 9.5E-36 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 9.5E-36 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 9.5E-36 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 9.5E-36 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 9.5E-36 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 9.5E-36 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 9.5E-36 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 414 9.5E-36 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 Gene3D G3DSA:3.50.50.60 3 143 3.3E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 Gene3D G3DSA:3.50.50.60 270 330 3.3E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 445 1.4E-18 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 310 6.8E-37 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 SUPERFAMILY SSF51905 1 326 8.03E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.0E-15 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 4.0E-15 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 4.0E-15 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 4.0E-15 T 09-03-2017 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 Gene3D G3DSA:3.30.390.30 340 450 2.1E-25 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 Gene3D G3DSA:3.50.50.60 153 269 3.3E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09885 1bfbe6967d7160d75f623bba26999079 475 SUPERFAMILY SSF55424 338 455 1.13E-24 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 166 216 3.3E-14 T 09-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 631 32.872 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 SUPERFAMILY SSF52954 524 629 2.42E-24 T 09-03-2017 IPR004154 Anticodon-binding L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 SUPERFAMILY SSF55186 64 238 1.57E-58 T 09-03-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 320 526 5.2E-38 T 09-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 626 2.1E-214 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 Gene3D G3DSA:3.30.980.10 65 129 7.7E-38 T 09-03-2017 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 Gene3D G3DSA:3.30.980.10 185 220 7.7E-38 T 09-03-2017 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 Pfam PF02824 TGS domain 2 61 6.2E-12 T 09-03-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 SMART SM00863 166 216 1.1E-21 T 09-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 SUPERFAMILY SSF55681 240 523 2.58E-97 T 09-03-2017 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 504 517 2.4E-51 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 326 354 2.4E-51 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 461 489 2.4E-51 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 359 382 2.4E-51 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 531 543 2.4E-51 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 Gene3D G3DSA:3.30.54.20 131 184 2.8E-13 T 09-03-2017 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 Pfam PF03129 Anticodon binding domain 538 627 1.3E-16 T 09-03-2017 IPR004154 Anticodon-binding L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 Gene3D G3DSA:3.30.930.10 239 527 4.2E-119 T 09-03-2017 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 Gene3D G3DSA:3.10.20.30 1 64 2.1E-19 T 09-03-2017 IPR012675 Beta-grasp domain L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 SUPERFAMILY SSF81271 2 61 5.89E-14 T 09-03-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 L21SP3_RS07335 ab0703b84929d4017c506f2004cd1b20 640 Gene3D G3DSA:3.40.50.800 529 634 1.5E-28 T 09-03-2017 IPR004154 Anticodon-binding L21SP3_RS04895 10d5f7d9c8dd7f39005f7c8609e32f02 350 Gene3D G3DSA:3.90.25.10 311 346 6.5E-23 T 09-03-2017 L21SP3_RS04895 10d5f7d9c8dd7f39005f7c8609e32f02 350 Gene3D G3DSA:3.90.25.10 212 246 6.5E-23 T 09-03-2017 L21SP3_RS04895 10d5f7d9c8dd7f39005f7c8609e32f02 350 PRINTS PR01713 Nucleotide sugar epimerase signature 231 246 2.3E-28 T 09-03-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 L21SP3_RS04895 10d5f7d9c8dd7f39005f7c8609e32f02 350 PRINTS PR01713 Nucleotide sugar epimerase signature 310 327 2.3E-28 T 09-03-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 L21SP3_RS04895 10d5f7d9c8dd7f39005f7c8609e32f02 350 PRINTS PR01713 Nucleotide sugar epimerase signature 271 286 2.3E-28 T 09-03-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 L21SP3_RS04895 10d5f7d9c8dd7f39005f7c8609e32f02 350 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 2.3E-28 T 09-03-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 L21SP3_RS04895 10d5f7d9c8dd7f39005f7c8609e32f02 350 SUPERFAMILY SSF51735 1 349 7.3E-88 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04895 10d5f7d9c8dd7f39005f7c8609e32f02 350 Gene3D G3DSA:3.40.50.720 1 211 2.3E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04895 10d5f7d9c8dd7f39005f7c8609e32f02 350 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 339 1.4E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS10095 e8d1b69e18d292ec27b3134b96326d7e 265 PRINTS PR01438 Universal stress protein signature 225 237 7.3E-8 T 09-03-2017 IPR006015 Universal stress protein A L21SP3_RS10095 e8d1b69e18d292ec27b3134b96326d7e 265 PRINTS PR01438 Universal stress protein signature 2 20 7.3E-8 T 09-03-2017 IPR006015 Universal stress protein A L21SP3_RS10095 e8d1b69e18d292ec27b3134b96326d7e 265 PRINTS PR01438 Universal stress protein signature 243 265 7.3E-8 T 09-03-2017 IPR006015 Universal stress protein A L21SP3_RS10095 e8d1b69e18d292ec27b3134b96326d7e 265 SUPERFAMILY SSF52402 1 126 2.43E-15 T 09-03-2017 L21SP3_RS10095 e8d1b69e18d292ec27b3134b96326d7e 265 Pfam PF00582 Universal stress protein family 139 265 1.0E-12 T 09-03-2017 IPR006016 UspA GO:0006950 L21SP3_RS10095 e8d1b69e18d292ec27b3134b96326d7e 265 Pfam PF00582 Universal stress protein family 55 125 6.4E-7 T 09-03-2017 IPR006016 UspA GO:0006950 L21SP3_RS10095 e8d1b69e18d292ec27b3134b96326d7e 265 SUPERFAMILY SSF52402 136 265 2.68E-15 T 09-03-2017 L21SP3_RS10095 e8d1b69e18d292ec27b3134b96326d7e 265 Gene3D G3DSA:3.40.50.620 41 127 1.0E-12 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS10095 e8d1b69e18d292ec27b3134b96326d7e 265 Gene3D G3DSA:3.40.50.620 139 265 5.8E-17 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS08650 f33c03484fda7f81fcc75657cde31c9f 142 Gene3D G3DSA:3.90.1180.10 4 141 5.9E-62 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS08650 f33c03484fda7f81fcc75657cde31c9f 142 SUPERFAMILY SSF52161 1 139 3.66E-57 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS08650 f33c03484fda7f81fcc75657cde31c9f 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.367 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS08650 f33c03484fda7f81fcc75657cde31c9f 142 Pfam PF00572 Ribosomal protein L13 14 138 4.2E-56 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS08650 f33c03484fda7f81fcc75657cde31c9f 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 141 4.8E-60 T 09-03-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS08650 f33c03484fda7f81fcc75657cde31c9f 142 PIRSF PIRSF002181 1 141 4.1E-50 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS04705 c73f686f46876265c1acf91b90ffc6ec 198 Pfam PF08281 Sigma-70, region 4 121 169 4.5E-6 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS04705 c73f686f46876265c1acf91b90ffc6ec 198 SUPERFAMILY SSF88659 111 173 9.72E-8 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS04705 c73f686f46876265c1acf91b90ffc6ec 198 SUPERFAMILY SSF88946 4 104 4.4E-24 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS04705 c73f686f46876265c1acf91b90ffc6ec 198 Gene3D G3DSA:1.10.10.10 111 173 1.4E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS04705 c73f686f46876265c1acf91b90ffc6ec 198 Gene3D G3DSA:1.10.1740.10 7 108 5.8E-26 T 09-03-2017 L21SP3_RS04705 c73f686f46876265c1acf91b90ffc6ec 198 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 50 81 - T 09-03-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS04705 c73f686f46876265c1acf91b90ffc6ec 198 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 173 2.1E-26 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS04705 c73f686f46876265c1acf91b90ffc6ec 198 Pfam PF04542 Sigma-70 region 2 31 92 1.0E-13 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 Gene3D G3DSA:2.60.120.200 1192 1407 2.9E-51 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 Pfam PF14509 Glycosyl-hydrolase 97 C-terminal, oligomerisation 529 622 1.5E-20 T 09-03-2017 IPR029483 Glycosyl-hydrolase 97, C-terminal oligomerisation domain L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 Pfam PF03422 Carbohydrate binding module (family 6) 1001 1108 9.7E-9 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 SUPERFAMILY SSF49899 1192 1409 2.68E-44 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 Gene3D G3DSA:2.160.20.10 1680 1808 1.6E-22 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 Gene3D G3DSA:2.160.20.10 2061 2218 1.6E-22 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 Gene3D G3DSA:2.160.20.10 1894 1987 1.6E-22 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 ProSitePatterns PS00018 EF-hand calcium-binding domain. 913 925 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 Pfam PF00722 Glycosyl hydrolases family 16 1229 1403 3.3E-22 T 09-03-2017 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 Gene3D G3DSA:2.60.120.260 1554 1678 3.4E-5 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 SUPERFAMILY SSF49785 970 1109 7.48E-15 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 SUPERFAMILY SSF51445 289 503 2.26E-12 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 SUPERFAMILY SSF51126 1682 1816 1.63E-28 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 SUPERFAMILY SSF51126 1889 1984 1.63E-28 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 SUPERFAMILY SSF51126 2055 2201 1.63E-28 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 SUPERFAMILY SSF49785 1555 1678 9.78E-5 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 Pfam PF14508 Glycosyl-hydrolase 97 N-terminal 25 273 2.3E-40 T 09-03-2017 IPR029486 Glycosyl-hydrolase 97, N-terminal domain L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 Pfam PF10566 Glycoside hydrolase 97 284 527 9.3E-55 T 09-03-2017 IPR019563 Glycosyl-hydrolase 97, catalytic domain L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 SMART SM00606 957 1110 0.0019 T 09-03-2017 IPR006584 Cellulose binding, type IV GO:0030246 L21SP3_RS09330 ed75988888beded0d092912619ca9d95 2219 Gene3D G3DSA:2.60.120.260 970 1109 5.7E-21 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS03600 59e0f150a30a0d61c30526ee8282e224 451 Pfam PF06439 Domain of Unknown Function (DUF1080) 25 210 4.8E-41 T 09-03-2017 IPR010496 Domain of unknown function DUF1080 L21SP3_RS03600 59e0f150a30a0d61c30526ee8282e224 451 Pfam PF06439 Domain of Unknown Function (DUF1080) 241 448 2.1E-46 T 09-03-2017 IPR010496 Domain of unknown function DUF1080 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 Pfam PF00581 Rhodanese-like domain 466 557 6.9E-15 T 09-03-2017 IPR001763 Rhodanese-like domain L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 SMART SM00450 466 563 8.9E-20 T 09-03-2017 IPR001763 Rhodanese-like domain L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 317 5.1E-65 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 SUPERFAMILY SSF52821 451 557 2.1E-28 T 09-03-2017 IPR001763 Rhodanese-like domain L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 Gene3D G3DSA:3.30.390.30 348 452 1.9E-36 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 187 5.4E-17 T 09-03-2017 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 5.4E-17 T 09-03-2017 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 288 295 5.4E-17 T 09-03-2017 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 398 413 5.4E-17 T 09-03-2017 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 247 261 5.4E-17 T 09-03-2017 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 Gene3D G3DSA:3.50.50.60 119 327 5.4E-60 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 340 446 2.1E-19 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 Gene3D G3DSA:3.40.250.10 453 557 2.9E-27 T 09-03-2017 IPR001763 Rhodanese-like domain L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 SUPERFAMILY SSF51905 5 328 1.98E-47 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 SUPERFAMILY SSF55424 334 458 2.41E-31 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 295 1.0E-23 T 09-03-2017 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.0E-23 T 09-03-2017 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 1.0E-23 T 09-03-2017 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 262 1.0E-23 T 09-03-2017 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 115 133 1.0E-23 T 09-03-2017 L21SP3_RS10380 d724a54fc6dbeaa7025fb5efa8f7b5a1 564 Gene3D G3DSA:3.50.50.60 3 118 6.5E-19 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10540 ae2f0c1a77959fd690f1c1726de899ca 146 Pfam PF12831 FAD dependent oxidoreductase 16 133 6.3E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10540 ae2f0c1a77959fd690f1c1726de899ca 146 SUPERFAMILY SSF51905 13 133 5.74E-11 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10540 ae2f0c1a77959fd690f1c1726de899ca 146 Gene3D G3DSA:3.50.50.60 14 134 1.4E-12 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS01375 6d2e0d2d300201563e3a6f20ea435c48 484 SUPERFAMILY SSF55681 146 478 9.0E-108 T 09-03-2017 L21SP3_RS01375 6d2e0d2d300201563e3a6f20ea435c48 484 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 6 480 4.9E-174 T 09-03-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01375 6d2e0d2d300201563e3a6f20ea435c48 484 Gene3D G3DSA:3.30.930.10 141 476 1.2E-111 T 09-03-2017 L21SP3_RS01375 6d2e0d2d300201563e3a6f20ea435c48 484 Gene3D G3DSA:2.40.50.140 7 139 3.7E-35 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS01375 6d2e0d2d300201563e3a6f20ea435c48 484 PRINTS PR00982 Lysyl-tRNA synthetase signature 183 193 5.0E-36 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01375 6d2e0d2d300201563e3a6f20ea435c48 484 PRINTS PR00982 Lysyl-tRNA synthetase signature 246 263 5.0E-36 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01375 6d2e0d2d300201563e3a6f20ea435c48 484 PRINTS PR00982 Lysyl-tRNA synthetase signature 228 241 5.0E-36 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01375 6d2e0d2d300201563e3a6f20ea435c48 484 PRINTS PR00982 Lysyl-tRNA synthetase signature 365 381 5.0E-36 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01375 6d2e0d2d300201563e3a6f20ea435c48 484 PRINTS PR00982 Lysyl-tRNA synthetase signature 199 215 5.0E-36 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01375 6d2e0d2d300201563e3a6f20ea435c48 484 SUPERFAMILY SSF50249 5 139 5.88E-30 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS01375 6d2e0d2d300201563e3a6f20ea435c48 484 Pfam PF01336 OB-fold nucleic acid binding domain 56 130 2.1E-12 T 09-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 L21SP3_RS01375 6d2e0d2d300201563e3a6f20ea435c48 484 Pfam PF00152 tRNA synthetases class II (D, K and N) 147 477 2.7E-84 T 09-03-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS01375 6d2e0d2d300201563e3a6f20ea435c48 484 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 11 480 39.28 T 09-03-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01175 858b3bba180962f99a22c57599c76fc5 176 Pfam PF05683 Fumarase C-terminus 9 174 2.9E-51 T 09-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 L21SP3_RS01175 858b3bba180962f99a22c57599c76fc5 176 Gene3D G3DSA:3.20.130.10 4 174 5.6E-63 T 09-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 L21SP3_RS01175 858b3bba180962f99a22c57599c76fc5 176 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 14 175 3.8E-48 T 09-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 L21SP3_RS01175 858b3bba180962f99a22c57599c76fc5 176 SUPERFAMILY SSF117457 5 174 2.75E-55 T 09-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 L21SP3_RS08830 49951e7e6e97bc802e1f3808c047b4f0 333 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 25 1.8E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS08830 49951e7e6e97bc802e1f3808c047b4f0 333 PRINTS PR00813 Bacterial general secretion pathway protein G signature 5 30 3.4E-7 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS08830 49951e7e6e97bc802e1f3808c047b4f0 333 PRINTS PR00813 Bacterial general secretion pathway protein G signature 41 59 3.4E-7 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS08830 49951e7e6e97bc802e1f3808c047b4f0 333 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS08830 49951e7e6e97bc802e1f3808c047b4f0 333 SUPERFAMILY SSF54523 6 86 2.51E-13 T 09-03-2017 L21SP3_RS08830 49951e7e6e97bc802e1f3808c047b4f0 333 Gene3D G3DSA:3.30.700.10 6 36 4.0E-6 T 09-03-2017 L21SP3_RS08830 49951e7e6e97bc802e1f3808c047b4f0 333 Pfam PF13633 Prokaryotic N-terminal methylation site 4 29 3.6E-10 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS11800 62a876654ec112f243a7a45f464ac088 444 Gene3D G3DSA:3.30.70.1170 197 251 1.4E-7 T 09-03-2017 L21SP3_RS11800 62a876654ec112f243a7a45f464ac088 444 Pfam PF01029 NusB family 2 119 2.1E-17 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 L21SP3_RS11800 62a876654ec112f243a7a45f464ac088 444 Gene3D G3DSA:3.40.50.150 261 426 4.1E-38 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS11800 62a876654ec112f243a7a45f464ac088 444 Pfam PF01189 16S rRNA methyltransferase RsmB/F 262 434 8.9E-39 T 09-03-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP3_RS11800 62a876654ec112f243a7a45f464ac088 444 SUPERFAMILY SSF53335 160 426 4.26E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS11800 62a876654ec112f243a7a45f464ac088 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 388 404 2.4E-13 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP3_RS11800 62a876654ec112f243a7a45f464ac088 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 338 350 2.4E-13 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP3_RS11800 62a876654ec112f243a7a45f464ac088 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 272 282 2.4E-13 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP3_RS11800 62a876654ec112f243a7a45f464ac088 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 243 257 2.4E-13 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP3_RS11800 62a876654ec112f243a7a45f464ac088 444 SUPERFAMILY SSF48013 1 121 7.19E-18 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 L21SP3_RS11800 62a876654ec112f243a7a45f464ac088 444 Gene3D G3DSA:1.10.940.10 161 171 8.3E-19 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 L21SP3_RS11800 62a876654ec112f243a7a45f464ac088 444 Gene3D G3DSA:1.10.940.10 1 125 8.3E-19 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 SUPERFAMILY SSF55785 120 189 4.01E-6 T 09-03-2017 IPR000014 PAS domain L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 Gene3D G3DSA:3.30.450.20 120 196 2.8E-11 T 09-03-2017 L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 SMART SM00086 145 187 0.03 T 09-03-2017 IPR001610 PAC motif L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 SMART SM00086 273 316 1.7E-9 T 09-03-2017 IPR001610 PAC motif L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 Pfam PF07730 Histidine kinase 352 419 1.3E-7 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 Pfam PF08447 PAS fold 222 309 1.7E-25 T 09-03-2017 IPR013655 PAS fold-3 GO:0005515 L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 SMART SM00387 457 551 5.5E-9 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 461 549 3.3E-9 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 Gene3D G3DSA:3.30.450.20 197 333 9.7E-36 T 09-03-2017 L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 SUPERFAMILY SSF55785 205 317 5.23E-23 T 09-03-2017 IPR000014 PAS domain L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 SUPERFAMILY SSF55874 420 548 2.36E-17 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 SMART SM00091 199 267 0.0016 T 09-03-2017 IPR000014 PAS domain L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 119 194 1.9E-8 T 09-03-2017 IPR000014 PAS domain L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 196 323 5.4E-11 T 09-03-2017 IPR000014 PAS domain L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 Gene3D G3DSA:3.30.565.10 432 549 3.9E-12 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 507 3.2E-5 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 529 3.2E-5 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS00675 3bb35dcad1b8cc33a42c098138d73f95 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 535 548 3.2E-5 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS03755 c6bec77098a79078984cde119fcb143d 540 Gene3D G3DSA:3.40.50.2300 3 130 2.5E-37 T 09-03-2017 L21SP3_RS03755 c6bec77098a79078984cde119fcb143d 540 SMART SM00448 3 115 8.1E-34 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS03755 c6bec77098a79078984cde119fcb143d 540 SMART SM00331 157 381 9.9E-17 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP3_RS03755 c6bec77098a79078984cde119fcb143d 540 Gene3D G3DSA:3.30.565.10 433 519 4.8E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS03755 c6bec77098a79078984cde119fcb143d 540 SUPERFAMILY SSF55874 438 519 9.89E-8 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS03755 c6bec77098a79078984cde119fcb143d 540 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 184 378 2.3E-27 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP3_RS03755 c6bec77098a79078984cde119fcb143d 540 Pfam PF00072 Response regulator receiver domain 6 114 1.5E-29 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS03755 c6bec77098a79078984cde119fcb143d 540 SUPERFAMILY SSF52172 4 141 2.85E-37 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS03755 c6bec77098a79078984cde119fcb143d 540 Pfam PF13581 Histidine kinase-like ATPase domain 413 523 2.0E-9 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS09895 a7bb58c6db2fd4ed702891e85614c68a 449 Gene3D G3DSA:2.60.120.230 222 275 8.0E-5 T 09-03-2017 IPR014784 Copper type II, ascorbate-dependent monooxygenase-like, C-terminal GO:0016715|GO:0055114 L21SP3_RS09895 a7bb58c6db2fd4ed702891e85614c68a 449 SUPERFAMILY SSF49742 314 428 2.72E-13 T 09-03-2017 IPR008977 PHM/PNGase F domain GO:0003824 L21SP3_RS09895 a7bb58c6db2fd4ed702891e85614c68a 449 Gene3D G3DSA:2.60.120.230 291 430 6.2E-14 T 09-03-2017 IPR014784 Copper type II, ascorbate-dependent monooxygenase-like, C-terminal GO:0016715|GO:0055114 L21SP3_RS09895 a7bb58c6db2fd4ed702891e85614c68a 449 Pfam PF09113 Peptide-N-glycosidase F, C terminal 317 425 7.3E-13 T 09-03-2017 IPR015197 Peptide-N-glycosidase F, C-terminal L21SP3_RS08595 357d692b1ecfcb69010e848655cdc45a 552 Gene3D G3DSA:1.10.601.10 166 438 4.5E-26 T 09-03-2017 L21SP3_RS08595 357d692b1ecfcb69010e848655cdc45a 552 Pfam PF02796 Helix-turn-helix domain of resolvase 228 264 1.1E-7 T 09-03-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 L21SP3_RS08595 357d692b1ecfcb69010e848655cdc45a 552 Gene3D G3DSA:1.10.10.10 483 546 2.8E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS08595 357d692b1ecfcb69010e848655cdc45a 552 SUPERFAMILY SSF88946 152 443 3.14E-25 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS08595 357d692b1ecfcb69010e848655cdc45a 552 SUPERFAMILY SSF88659 484 546 3.36E-13 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS08595 357d692b1ecfcb69010e848655cdc45a 552 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 512 538 - T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS08595 357d692b1ecfcb69010e848655cdc45a 552 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 380 542 2.2E-21 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS08595 357d692b1ecfcb69010e848655cdc45a 552 Pfam PF04542 Sigma-70 region 2 382 439 2.4E-9 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS08595 357d692b1ecfcb69010e848655cdc45a 552 PRINTS PR00046 Major sigma-70 factor signature 429 437 4.0E-13 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS08595 357d692b1ecfcb69010e848655cdc45a 552 PRINTS PR00046 Major sigma-70 factor signature 527 538 4.0E-13 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS08595 357d692b1ecfcb69010e848655cdc45a 552 PRINTS PR00046 Major sigma-70 factor signature 405 418 4.0E-13 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS08595 357d692b1ecfcb69010e848655cdc45a 552 PRINTS PR00046 Major sigma-70 factor signature 512 527 4.0E-13 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS08595 357d692b1ecfcb69010e848655cdc45a 552 Pfam PF04545 Sigma-70, region 4 485 540 2.4E-13 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09760 feea9fa5a5a63426a74cf5367141e8ed 570 Pfam PF00664 ABC transporter transmembrane region 16 285 9.4E-52 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 L21SP3_RS09760 feea9fa5a5a63426a74cf5367141e8ed 570 Pfam PF00005 ABC transporter 349 498 2.1E-33 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS09760 feea9fa5a5a63426a74cf5367141e8ed 570 SMART SM00382 358 544 4.4E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS09760 feea9fa5a5a63426a74cf5367141e8ed 570 Gene3D G3DSA:3.40.50.300 332 562 2.6E-82 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09760 feea9fa5a5a63426a74cf5367141e8ed 570 SUPERFAMILY SSF90123 3 321 9.81E-79 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 L21SP3_RS09760 feea9fa5a5a63426a74cf5367141e8ed 570 Gene3D G3DSA:1.20.1560.10 3 315 9.7E-78 T 09-03-2017 L21SP3_RS09760 feea9fa5a5a63426a74cf5367141e8ed 570 SUPERFAMILY SSF52540 323 568 1.74E-91 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09760 feea9fa5a5a63426a74cf5367141e8ed 570 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 Gene3D G3DSA:3.30.70.20 129 194 2.6E-13 T 09-03-2017 L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 SUPERFAMILY SSF54292 1 74 6.17E-19 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 189 200 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 Pfam PF12838 4Fe-4S dicluster domain 145 203 5.2E-7 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 SMART SM00929 83 123 2.0E-19 T 09-03-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 SUPERFAMILY SSF54862 75 211 5.86E-35 T 09-03-2017 L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 Gene3D G3DSA:4.10.260.20 529 587 1.8E-22 T 09-03-2017 IPR003149 Iron hydrogenase, small subunit L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 SUPERFAMILY SSF53920 189 583 1.96E-121 T 09-03-2017 IPR009016 Iron hydrogenase L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 Gene3D G3DSA:3.40.50.1780 305 435 3.0E-78 T 09-03-2017 L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 Gene3D G3DSA:3.40.50.1780 195 247 3.0E-78 T 09-03-2017 L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 222 522 2.0E-92 T 09-03-2017 IPR004108 Iron hydrogenase, large subunit, C-terminal L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 09-03-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 76 3.5E-19 T 09-03-2017 L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 Gene3D G3DSA:3.10.20.30 2 57 1.3E-7 T 09-03-2017 IPR012675 Beta-grasp domain L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 SMART SM00902 527 586 4.1E-20 T 09-03-2017 IPR003149 Iron hydrogenase, small subunit L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 121 2.8E-17 T 09-03-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 139 526 4.0E-156 T 09-03-2017 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 L21SP3_RS00170 08620868c0649b59903ad60ca216e127 590 Pfam PF02256 Iron hydrogenase small subunit 531 584 2.7E-21 T 09-03-2017 IPR003149 Iron hydrogenase, small subunit L21SP3_RS05370 ffac6aaed5dab85a88773934c4911d1f 430 Pfam PF13439 Glycosyltransferase Family 4 14 181 2.6E-35 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 L21SP3_RS05370 ffac6aaed5dab85a88773934c4911d1f 430 Pfam PF00534 Glycosyl transferases group 1 191 350 4.6E-33 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS05370 ffac6aaed5dab85a88773934c4911d1f 430 SUPERFAMILY SSF53756 2 379 1.15E-87 T 09-03-2017 L21SP3_RS05370 ffac6aaed5dab85a88773934c4911d1f 430 Gene3D G3DSA:3.40.50.2000 169 356 4.8E-33 T 09-03-2017 L21SP3_RS10290 efdf28bfb3f5697c223ec9e495315922 404 Pfam PF01609 Transposase DDE domain 208 320 6.5E-10 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 SUPERFAMILY SSF54980 398 476 1.65E-22 T 09-03-2017 IPR009022 Elongation factor G, III-V domain L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 Pfam PF14492 Elongation Factor G, domain II 400 474 9.3E-31 T 09-03-2017 IPR009022 Elongation factor G, III-V domain L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 SMART SM00889 476 599 1.0E-61 T 09-03-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 Pfam PF00679 Elongation factor G C-terminus 602 687 2.3E-24 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 Gene3D G3DSA:3.40.50.300 2 283 3.8E-100 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 PRINTS PR00315 GTP-binding elongation factor signature 127 136 2.4E-15 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 PRINTS PR00315 GTP-binding elongation factor signature 91 102 2.4E-15 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.4E-15 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 PRINTS PR00315 GTP-binding elongation factor signature 55 63 2.4E-15 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 PRINTS PR00315 GTP-binding elongation factor signature 75 85 2.4E-15 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 SUPERFAMILY SSF52540 3 278 2.83E-102 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 TIGRFAM TIGR00484 EF-G: translation elongation factor G 3 689 1.3E-288 T 09-03-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 Pfam PF03144 Elongation factor Tu domain 2 322 387 4.3E-14 T 09-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 SUPERFAMILY SSF54211 475 600 2.78E-39 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 SUPERFAMILY SSF50447 261 400 1.96E-31 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 09-03-2017 IPR031157 Tr-type G domain, conserved site L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 Gene3D G3DSA:3.30.70.240 598 687 1.2E-24 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 Gene3D G3DSA:2.40.30.10 301 401 5.4E-34 T 09-03-2017 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 Gene3D G3DSA:3.30.70.870 402 476 7.4E-32 T 09-03-2017 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 SUPERFAMILY SSF54980 602 689 1.2E-22 T 09-03-2017 IPR009022 Elongation factor G, III-V domain L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 Hamap MF_00054_B Elongation factor G [fusA]. 3 691 96.072 T 09-03-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 Gene3D G3DSA:3.30.230.10 480 597 2.0E-45 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 Pfam PF00009 Elongation factor Tu GTP binding domain 6 278 1.1E-65 T 09-03-2017 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 SMART SM00838 601 688 3.8E-35 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 177 4.1E-36 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP3_RS04025 2e5289054b9c4dbc5379d7dca7e394c5 691 Pfam PF03764 Elongation factor G, domain IV 475 598 5.7E-40 T 09-03-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 L21SP3_RS02900 5773197cc4d603fd81e9aa3a4ff4e9ff 264 Gene3D G3DSA:3.30.2010.10 75 151 1.3E-13 T 09-03-2017 L21SP3_RS02900 5773197cc4d603fd81e9aa3a4ff4e9ff 264 Pfam PF01435 Peptidase family M48 90 247 1.4E-34 T 09-03-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 L21SP3_RS05595 a30dd508d4cffdb1c09a5a357d539b82 568 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 427 446 - T 09-03-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 L21SP3_RS05595 a30dd508d4cffdb1c09a5a357d539b82 568 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 390 537 1.4E-50 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 L21SP3_RS05595 a30dd508d4cffdb1c09a5a357d539b82 568 Gene3D G3DSA:3.40.50.970 9 180 1.7E-70 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS05595 a30dd508d4cffdb1c09a5a357d539b82 568 Gene3D G3DSA:3.40.50.970 353 552 6.5E-76 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS05595 a30dd508d4cffdb1c09a5a357d539b82 568 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 10 560 2.3E-254 T 09-03-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 L21SP3_RS05595 a30dd508d4cffdb1c09a5a357d539b82 568 SUPERFAMILY SSF52518 9 189 1.37E-59 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS05595 a30dd508d4cffdb1c09a5a357d539b82 568 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 333 6.8E-48 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 L21SP3_RS05595 a30dd508d4cffdb1c09a5a357d539b82 568 SUPERFAMILY SSF52467 192 358 4.55E-65 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain L21SP3_RS05595 a30dd508d4cffdb1c09a5a357d539b82 568 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 170 1.8E-55 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 L21SP3_RS05595 a30dd508d4cffdb1c09a5a357d539b82 568 Gene3D G3DSA:3.40.50.1220 192 352 2.1E-70 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain L21SP3_RS05595 a30dd508d4cffdb1c09a5a357d539b82 568 SUPERFAMILY SSF52518 367 559 8.18E-69 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS11160 daeb6a9f4322f044d4cc291f6889c2eb 701 Pfam PF02503 Polyphosphate kinase middle domain 121 319 4.8E-51 T 09-03-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 L21SP3_RS11160 daeb6a9f4322f044d4cc291f6889c2eb 701 SUPERFAMILY SSF140356 8 108 9.55E-35 T 09-03-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 L21SP3_RS11160 daeb6a9f4322f044d4cc291f6889c2eb 701 Hamap MF_00347 Polyphosphate kinase [ppk]. 4 679 30.652 T 09-03-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 L21SP3_RS11160 daeb6a9f4322f044d4cc291f6889c2eb 701 Gene3D G3DSA:3.30.870.10 498 681 1.6E-74 T 09-03-2017 L21SP3_RS11160 daeb6a9f4322f044d4cc291f6889c2eb 701 Pfam PF13090 Polyphosphate kinase C-terminal domain 328 675 5.7E-155 T 09-03-2017 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 L21SP3_RS11160 daeb6a9f4322f044d4cc291f6889c2eb 701 PIRSF PIRSF015589 1 693 1.4E-262 T 09-03-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 L21SP3_RS11160 daeb6a9f4322f044d4cc291f6889c2eb 701 Gene3D G3DSA:3.30.1840.10 113 298 6.8E-48 T 09-03-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 L21SP3_RS11160 daeb6a9f4322f044d4cc291f6889c2eb 701 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 8 675 3.6E-251 T 09-03-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 L21SP3_RS11160 daeb6a9f4322f044d4cc291f6889c2eb 701 SUPERFAMILY SSF56024 313 494 1.02E-53 T 09-03-2017 L21SP3_RS11160 daeb6a9f4322f044d4cc291f6889c2eb 701 SUPERFAMILY SSF143724 114 303 7.85E-44 T 09-03-2017 L21SP3_RS11160 daeb6a9f4322f044d4cc291f6889c2eb 701 Pfam PF13089 Polyphosphate kinase N-terminal domain 8 110 1.8E-35 T 09-03-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 L21SP3_RS11160 daeb6a9f4322f044d4cc291f6889c2eb 701 SUPERFAMILY SSF56024 498 677 1.14E-69 T 09-03-2017 L21SP3_RS11160 daeb6a9f4322f044d4cc291f6889c2eb 701 Gene3D G3DSA:3.30.870.10 313 497 1.0E-72 T 09-03-2017 L21SP3_RS06935 38aa42cff2b800a0601ced0ea41d236f 415 Gene3D G3DSA:2.40.440.10 279 413 3.0E-26 T 09-03-2017 L21SP3_RS06935 38aa42cff2b800a0601ced0ea41d236f 415 SUPERFAMILY SSF141523 278 407 2.62E-22 T 09-03-2017 L21SP3_RS06935 38aa42cff2b800a0601ced0ea41d236f 415 SMART SM00257 232 276 0.0051 T 09-03-2017 IPR018392 LysM domain L21SP3_RS06935 38aa42cff2b800a0601ced0ea41d236f 415 SUPERFAMILY SSF54106 231 275 3.66E-7 T 09-03-2017 IPR018392 LysM domain L21SP3_RS06935 38aa42cff2b800a0601ced0ea41d236f 415 Pfam PF01476 LysM domain 233 275 5.0E-6 T 09-03-2017 IPR018392 LysM domain L21SP3_RS06935 38aa42cff2b800a0601ced0ea41d236f 415 Pfam PF03734 L,D-transpeptidase catalytic domain 282 411 2.4E-17 T 09-03-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 L21SP3_RS06935 38aa42cff2b800a0601ced0ea41d236f 415 Gene3D G3DSA:3.10.350.10 231 275 1.2E-9 T 09-03-2017 IPR018392 LysM domain L21SP3_RS04870 b96f99787321006a7651393fd832f4f0 433 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 10 188 2.1E-44 T 09-03-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS04870 b96f99787321006a7651393fd832f4f0 433 SUPERFAMILY SSF51735 10 200 4.32E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04870 b96f99787321006a7651393fd832f4f0 433 Gene3D G3DSA:3.40.50.720 9 227 1.9E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04870 b96f99787321006a7651393fd832f4f0 433 Gene3D G3DSA:3.40.50.720 237 424 1.1E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04870 b96f99787321006a7651393fd832f4f0 433 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 324 422 6.4E-25 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS04870 b96f99787321006a7651393fd832f4f0 433 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 10 418 3.0E-133 T 09-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS04870 b96f99787321006a7651393fd832f4f0 433 PIRSF PIRSF000124 9 431 4.9E-63 T 09-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS04870 b96f99787321006a7651393fd832f4f0 433 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 207 297 1.9E-28 T 09-03-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS04870 b96f99787321006a7651393fd832f4f0 433 SMART SM00984 324 422 3.8E-33 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS04870 b96f99787321006a7651393fd832f4f0 433 SUPERFAMILY SSF48179 206 299 2.38E-29 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP3_RS04870 b96f99787321006a7651393fd832f4f0 433 SUPERFAMILY SSF52413 311 422 4.19E-28 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 L21SP3_RS04870 b96f99787321006a7651393fd832f4f0 433 PIRSF PIRSF500136 1 433 6.4E-154 T 09-03-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 L21SP3_RS06215 d045a78a897e255018adaf28ad2b743f 104 Pfam PF00338 Ribosomal protein S10p/S20e 9 103 2.4E-35 T 09-03-2017 IPR027486 Ribosomal protein S10 domain L21SP3_RS06215 d045a78a897e255018adaf28ad2b743f 104 SUPERFAMILY SSF54999 7 103 2.09E-36 T 09-03-2017 IPR027486 Ribosomal protein S10 domain L21SP3_RS06215 d045a78a897e255018adaf28ad2b743f 104 PRINTS PR00971 Ribosomal protein S10 family signature 63 77 6.5E-20 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06215 d045a78a897e255018adaf28ad2b743f 104 PRINTS PR00971 Ribosomal protein S10 family signature 7 20 6.5E-20 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06215 d045a78a897e255018adaf28ad2b743f 104 PRINTS PR00971 Ribosomal protein S10 family signature 42 57 6.5E-20 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06215 d045a78a897e255018adaf28ad2b743f 104 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 5 104 25.978 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06215 d045a78a897e255018adaf28ad2b743f 104 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 6 103 2.2E-42 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06215 d045a78a897e255018adaf28ad2b743f 104 Gene3D G3DSA:3.30.70.600 6 103 2.4E-42 T 09-03-2017 IPR027486 Ribosomal protein S10 domain L21SP3_RS06215 d045a78a897e255018adaf28ad2b743f 104 ProSitePatterns PS00361 Ribosomal protein S10 signature. 31 46 - T 09-03-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06215 d045a78a897e255018adaf28ad2b743f 104 SMART SM01403 9 103 6.0E-53 T 09-03-2017 IPR027486 Ribosomal protein S10 domain L21SP3_RS09265 2d75f267a2d20ffcafc283536ce6f0ba 710 SUPERFAMILY SSF52540 185 454 1.05E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09265 2d75f267a2d20ffcafc283536ce6f0ba 710 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 226 359 7.7E-44 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP3_RS09265 2d75f267a2d20ffcafc283536ce6f0ba 710 SMART SM00382 222 362 1.8E-22 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS09265 2d75f267a2d20ffcafc283536ce6f0ba 710 Pfam PF01434 Peptidase family M41 421 626 1.5E-74 T 09-03-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 L21SP3_RS09265 2d75f267a2d20ffcafc283536ce6f0ba 710 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 24 646 34.394 T 09-03-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 L21SP3_RS09265 2d75f267a2d20ffcafc283536ce6f0ba 710 Gene3D G3DSA:3.40.50.300 183 368 1.3E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09265 2d75f267a2d20ffcafc283536ce6f0ba 710 ProSitePatterns PS00674 AAA-protein family signature. 330 348 - T 09-03-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 L21SP3_RS09265 2d75f267a2d20ffcafc283536ce6f0ba 710 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 136 627 1.2E-216 T 09-03-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 L21SP3_RS09265 2d75f267a2d20ffcafc283536ce6f0ba 710 SUPERFAMILY SSF140990 441 631 5.62E-64 T 09-03-2017 L21SP3_RS09265 2d75f267a2d20ffcafc283536ce6f0ba 710 Gene3D G3DSA:1.10.8.60 369 434 5.0E-23 T 09-03-2017 L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 PRINTS PR00415 Aconitase family signature 186 199 6.8E-22 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 PRINTS PR00415 Aconitase family signature 349 362 6.8E-22 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 PRINTS PR00415 Aconitase family signature 200 213 6.8E-22 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 PRINTS PR00415 Aconitase family signature 124 139 6.8E-22 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 PRINTS PR00415 Aconitase family signature 110 123 6.8E-22 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 Gene3D G3DSA:3.40.1060.10 157 262 3.8E-36 T 09-03-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 Pfam PF00330 Aconitase family (aconitate hydratase) 8 407 1.0E-104 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 ProSitePatterns PS01244 Aconitase family signature 2. 349 362 - T 09-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 Gene3D G3DSA:3.30.499.10 270 427 4.8E-54 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 SUPERFAMILY SSF52016 445 649 7.06E-47 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 Pfam PF00694 Aconitase C-terminal domain 511 585 6.7E-23 T 09-03-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 SUPERFAMILY SSF53732 1 429 5.89E-142 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 Gene3D G3DSA:3.20.19.10 466 649 5.4E-46 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 ProSitePatterns PS00450 Aconitase family signature 1. 289 305 - T 09-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 4 652 2.8E-259 T 09-03-2017 IPR006250 Aconitase, putative L21SP3_RS00445 89dc397b1f5120cc2336f1a6faa6cfc3 654 Gene3D G3DSA:3.30.499.10 27 154 1.6E-38 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS10385 0d397d0535231d8ead17745fbb3a9b64 366 SUPERFAMILY SSF53756 49 356 5.76E-31 T 09-03-2017 L21SP3_RS10385 0d397d0535231d8ead17745fbb3a9b64 366 Pfam PF12038 Domain of unknown function (DUF3524) 6 175 1.9E-60 T 09-03-2017 IPR022701 Glycosyltransferase family 1, N-terminal L21SP3_RS10385 0d397d0535231d8ead17745fbb3a9b64 366 Pfam PF00534 Glycosyl transferases group 1 194 340 1.8E-13 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS10385 0d397d0535231d8ead17745fbb3a9b64 366 Gene3D G3DSA:3.40.50.2000 186 341 4.6E-8 T 09-03-2017 L21SP3_RS01045 d08faeecb5082a9962eb5b8728196e02 334 SUPERFAMILY SSF47648 2 68 3.4E-16 T 09-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 L21SP3_RS01045 d08faeecb5082a9962eb5b8728196e02 334 Gene3D G3DSA:3.40.1030.10 74 333 4.2E-102 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 L21SP3_RS01045 d08faeecb5082a9962eb5b8728196e02 334 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 65 1.2E-13 T 09-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 L21SP3_RS01045 d08faeecb5082a9962eb5b8728196e02 334 Pfam PF00591 Glycosyl transferase family, a/b domain 74 323 1.0E-90 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 L21SP3_RS01045 d08faeecb5082a9962eb5b8728196e02 334 SUPERFAMILY SSF52418 75 333 1.22E-91 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 L21SP3_RS01045 d08faeecb5082a9962eb5b8728196e02 334 Gene3D G3DSA:1.20.970.10 1 65 7.2E-21 T 09-03-2017 L21SP3_RS01045 d08faeecb5082a9962eb5b8728196e02 334 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 4 333 37.362 T 09-03-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 L21SP3_RS01045 d08faeecb5082a9962eb5b8728196e02 334 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 332 1.2E-123 T 09-03-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 L21SP3_RS06195 a268203382a293aac14baee69128f5d7 284 Gene3D G3DSA:2.30.30.30 119 195 6.8E-30 T 09-03-2017 IPR014722 Ribosomal protein L2 domain 2 L21SP3_RS06195 a268203382a293aac14baee69128f5d7 284 Gene3D G3DSA:2.40.50.140 1 113 3.0E-42 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS06195 a268203382a293aac14baee69128f5d7 284 PIRSF PIRSF002158 13 277 1.1E-83 T 09-03-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06195 a268203382a293aac14baee69128f5d7 284 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 4.9E-115 T 09-03-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06195 a268203382a293aac14baee69128f5d7 284 SMART SM01383 43 119 5.8E-36 T 09-03-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06195 a268203382a293aac14baee69128f5d7 284 SUPERFAMILY SSF50104 127 273 4.09E-55 T 09-03-2017 IPR008991 Translation protein SH3-like domain L21SP3_RS06195 a268203382a293aac14baee69128f5d7 284 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 127 251 3.7E-49 T 09-03-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06195 a268203382a293aac14baee69128f5d7 284 SMART SM01382 125 253 5.2E-76 T 09-03-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06195 a268203382a293aac14baee69128f5d7 284 SUPERFAMILY SSF50249 2 124 7.2E-40 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS06195 a268203382a293aac14baee69128f5d7 284 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 43.589 T 09-03-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06195 a268203382a293aac14baee69128f5d7 284 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 43 119 7.7E-27 T 09-03-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06195 a268203382a293aac14baee69128f5d7 284 Gene3D G3DSA:4.10.950.10 197 275 4.0E-26 T 09-03-2017 IPR014726 Ribosomal protein L2, domain 3 L21SP3_RS10010 b07b267e52fbe0ab275d7a709f89e4c0 369 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 254 264 - T 09-03-2017 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 L21SP3_RS10010 b07b267e52fbe0ab275d7a709f89e4c0 369 Pfam PF00331 Glycosyl hydrolase family 10 25 366 6.0E-108 T 09-03-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 L21SP3_RS10010 b07b267e52fbe0ab275d7a709f89e4c0 369 PRINTS PR00134 Glycosyl hydrolase family 10 signature 148 159 1.6E-16 T 09-03-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 L21SP3_RS10010 b07b267e52fbe0ab275d7a709f89e4c0 369 PRINTS PR00134 Glycosyl hydrolase family 10 signature 100 112 1.6E-16 T 09-03-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 L21SP3_RS10010 b07b267e52fbe0ab275d7a709f89e4c0 369 PRINTS PR00134 Glycosyl hydrolase family 10 signature 192 203 1.6E-16 T 09-03-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 L21SP3_RS10010 b07b267e52fbe0ab275d7a709f89e4c0 369 PRINTS PR00134 Glycosyl hydrolase family 10 signature 220 232 1.6E-16 T 09-03-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 L21SP3_RS10010 b07b267e52fbe0ab275d7a709f89e4c0 369 SUPERFAMILY SSF51445 23 367 1.77E-108 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS10010 b07b267e52fbe0ab275d7a709f89e4c0 369 SMART SM00633 69 368 7.7E-104 T 09-03-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 L21SP3_RS10010 b07b267e52fbe0ab275d7a709f89e4c0 369 Gene3D G3DSA:3.20.20.80 24 367 7.5E-112 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 Gene3D G3DSA:1.10.40.30 378 433 6.3E-26 T 09-03-2017 L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 PRINTS PR00145 Argininosuccinate lyase family signature 146 166 8.5E-57 T 09-03-2017 L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 PRINTS PR00145 Argininosuccinate lyase family signature 105 127 8.5E-57 T 09-03-2017 L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 PRINTS PR00145 Argininosuccinate lyase family signature 314 333 8.5E-57 T 09-03-2017 L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 PRINTS PR00145 Argininosuccinate lyase family signature 279 295 8.5E-57 T 09-03-2017 L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 PRINTS PR00145 Argininosuccinate lyase family signature 197 213 8.5E-57 T 09-03-2017 L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 PRINTS PR00145 Argininosuccinate lyase family signature 235 259 8.5E-57 T 09-03-2017 L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 Pfam PF00206 Lyase 11 304 2.9E-80 T 09-03-2017 IPR022761 Fumarate lyase, N-terminal L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 Hamap MF_00006 Argininosuccinate lyase [argH]. 6 457 39.135 T 09-03-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 SUPERFAMILY SSF48557 8 459 6.13E-133 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 PRINTS PR00149 Fumarate lyase superfamily signature 106 124 5.4E-25 T 09-03-2017 IPR000362 Fumarate lyase family L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 5.4E-25 T 09-03-2017 IPR000362 Fumarate lyase family L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 PRINTS PR00149 Fumarate lyase superfamily signature 151 169 5.4E-25 T 09-03-2017 IPR000362 Fumarate lyase family L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 PRINTS PR00149 Fumarate lyase superfamily signature 235 262 5.4E-25 T 09-03-2017 IPR000362 Fumarate lyase family L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 Gene3D G3DSA:1.20.200.10 111 377 3.2E-95 T 09-03-2017 L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 Gene3D G3DSA:1.10.275.10 6 110 1.6E-36 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 Pfam PF14698 Argininosuccinate lyase C-terminal 367 432 1.4E-20 T 09-03-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS08780 50296c2ed35bd4a06437dd8f61475515 461 TIGRFAM TIGR00838 argH: argininosuccinate lyase 8 459 4.3E-175 T 09-03-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS07060 49680536177aefb38507fffc506122f7 318 Gene3D G3DSA:3.30.420.40 143 296 1.5E-53 T 09-03-2017 L21SP3_RS07060 49680536177aefb38507fffc506122f7 318 Pfam PF00480 ROK family 5 312 8.9E-59 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 L21SP3_RS07060 49680536177aefb38507fffc506122f7 318 Gene3D G3DSA:3.30.420.40 1 142 4.0E-42 T 09-03-2017 L21SP3_RS07060 49680536177aefb38507fffc506122f7 318 SUPERFAMILY SSF53067 3 314 4.22E-58 T 09-03-2017 L21SP3_RS07060 49680536177aefb38507fffc506122f7 318 ProSitePatterns PS01125 ROK family signature. 138 165 - T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 L21SP3_RS02420 09fbccd966b33f1008eb1e7c81b636a2 306 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 305 1.8E-134 T 09-03-2017 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 L21SP3_RS02420 09fbccd966b33f1008eb1e7c81b636a2 306 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 305 6.9E-130 T 09-03-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 L21SP3_RS02420 09fbccd966b33f1008eb1e7c81b636a2 306 SUPERFAMILY SSF53686 3 305 4.58E-103 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP3_RS02420 09fbccd966b33f1008eb1e7c81b636a2 306 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 294 4.1E-70 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP3_RS02420 09fbccd966b33f1008eb1e7c81b636a2 306 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 09-03-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 L21SP3_RS02420 09fbccd966b33f1008eb1e7c81b636a2 306 Gene3D G3DSA:3.40.50.1100 38 135 1.9E-41 T 09-03-2017 L21SP3_RS02420 09fbccd966b33f1008eb1e7c81b636a2 306 Gene3D G3DSA:3.40.50.1100 136 305 9.1E-76 T 09-03-2017 L21SP3_RS04780 1284ef6ff36e1359d1ff3437e359ae59 369 SUPERFAMILY SSF51182 245 365 6.14E-20 T 09-03-2017 IPR011051 RmlC-like cupin domain L21SP3_RS04780 1284ef6ff36e1359d1ff3437e359ae59 369 Gene3D G3DSA:2.60.120.10 255 360 1.0E-15 T 09-03-2017 IPR014710 RmlC-like jelly roll fold L21SP3_RS04780 1284ef6ff36e1359d1ff3437e359ae59 369 SUPERFAMILY SSF51735 1 249 2.53E-24 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04780 1284ef6ff36e1359d1ff3437e359ae59 369 Gene3D G3DSA:3.40.50.720 1 181 3.8E-19 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04780 1284ef6ff36e1359d1ff3437e359ae59 369 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 166 1.2E-13 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 L21SP3_RS09240 27bf6728206de675b1785b9f456026f6 344 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 39 340 2.7E-61 T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 L21SP3_RS09240 27bf6728206de675b1785b9f456026f6 344 Gene3D G3DSA:3.20.20.210 36 341 2.1E-60 T 09-03-2017 L21SP3_RS09240 27bf6728206de675b1785b9f456026f6 344 SUPERFAMILY SSF51726 33 342 7.06E-57 T 09-03-2017 L21SP3_RS03155 e62e0da0dea60638ad239477ab10bb2d 940 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 565 572 - T 09-03-2017 IPR030458 Glycosyl hydrolases family 31, active site L21SP3_RS03155 e62e0da0dea60638ad239477ab10bb2d 940 SUPERFAMILY SSF51445 411 753 4.74E-88 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS03155 e62e0da0dea60638ad239477ab10bb2d 940 Pfam PF13802 Galactose mutarotase-like 311 376 1.9E-15 T 09-03-2017 IPR025887 Glycoside hydrolase family 31, N-terminal domain L21SP3_RS03155 e62e0da0dea60638ad239477ab10bb2d 940 SUPERFAMILY SSF74650 267 394 3.14E-19 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP3_RS03155 e62e0da0dea60638ad239477ab10bb2d 940 Pfam PF17137 Domain of unknown function (DUF5110) 844 909 3.9E-9 T 09-03-2017 IPR033403 Domain of unknown function DUF5110 L21SP3_RS03155 e62e0da0dea60638ad239477ab10bb2d 940 SUPERFAMILY SSF51011 756 806 2.88E-5 T 09-03-2017 L21SP3_RS03155 e62e0da0dea60638ad239477ab10bb2d 940 Pfam PF01055 Glycosyl hydrolases family 31 396 826 2.2E-129 T 09-03-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 L21SP3_RS03155 e62e0da0dea60638ad239477ab10bb2d 940 Gene3D G3DSA:3.20.20.70 436 591 6.3E-8 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS00950 32f3f83ab5aa8e8026bd87f21038dc10 460 SUPERFAMILY SSF51445 6 142 2.22E-11 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS00950 32f3f83ab5aa8e8026bd87f21038dc10 460 Gene3D G3DSA:3.20.20.80 12 139 1.9E-20 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS00950 32f3f83ab5aa8e8026bd87f21038dc10 460 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 335 390 4.0E-10 T 09-03-2017 IPR000772 Ricin B, lectin domain L21SP3_RS00950 32f3f83ab5aa8e8026bd87f21038dc10 460 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 250 328 9.8E-21 T 09-03-2017 IPR000772 Ricin B, lectin domain L21SP3_RS00950 32f3f83ab5aa8e8026bd87f21038dc10 460 SMART SM00458 250 389 3.4E-13 T 09-03-2017 IPR000772 Ricin B, lectin domain L21SP3_RS00950 32f3f83ab5aa8e8026bd87f21038dc10 460 SUPERFAMILY SSF50370 250 389 5.81E-39 T 09-03-2017 IPR000772 Ricin B, lectin domain L21SP3_RS00950 32f3f83ab5aa8e8026bd87f21038dc10 460 Gene3D G3DSA:2.60.40.1180 140 235 7.8E-13 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta L21SP3_RS00950 32f3f83ab5aa8e8026bd87f21038dc10 460 Gene3D G3DSA:2.80.10.50 253 390 4.9E-35 T 09-03-2017 L21SP3_RS02550 55f3b10cb7b2f3c4c9c44827865ab867 455 Pfam PF10396 GTP-binding protein TrmE N-terminus 7 123 4.5E-18 T 09-03-2017 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 L21SP3_RS02550 55f3b10cb7b2f3c4c9c44827865ab867 455 Gene3D G3DSA:1.20.120.430 125 185 1.2E-29 T 09-03-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 L21SP3_RS02550 55f3b10cb7b2f3c4c9c44827865ab867 455 Gene3D G3DSA:1.20.120.430 250 274 1.2E-29 T 09-03-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 L21SP3_RS02550 55f3b10cb7b2f3c4c9c44827865ab867 455 Gene3D G3DSA:1.20.120.430 385 455 1.2E-29 T 09-03-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 L21SP3_RS02550 55f3b10cb7b2f3c4c9c44827865ab867 455 SUPERFAMILY SSF116878 124 223 2.35E-23 T 09-03-2017 L21SP3_RS02550 55f3b10cb7b2f3c4c9c44827865ab867 455 SUPERFAMILY SSF116878 380 455 2.35E-23 T 09-03-2017 L21SP3_RS02550 55f3b10cb7b2f3c4c9c44827865ab867 455 Pfam PF01926 50S ribosome-binding GTPase 223 334 2.0E-15 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS02550 55f3b10cb7b2f3c4c9c44827865ab867 455 SUPERFAMILY SSF103025 6 123 8.63E-18 T 09-03-2017 L21SP3_RS02550 55f3b10cb7b2f3c4c9c44827865ab867 455 SUPERFAMILY SSF52540 217 377 3.61E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02550 55f3b10cb7b2f3c4c9c44827865ab867 455 Gene3D G3DSA:3.40.50.300 214 249 7.5E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02550 55f3b10cb7b2f3c4c9c44827865ab867 455 Gene3D G3DSA:3.30.1360.120 3 124 9.2E-21 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 L21SP3_RS02550 55f3b10cb7b2f3c4c9c44827865ab867 455 Pfam PF12631 MnmE helical domain 126 452 1.3E-27 T 09-03-2017 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 L21SP3_RS06095 77059fb31ea16b0a2e775312f166206d 38 Pfam PF00444 Ribosomal protein L36 1 38 2.7E-20 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06095 77059fb31ea16b0a2e775312f166206d 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 18.419 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06095 77059fb31ea16b0a2e775312f166206d 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 1.0E-20 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06095 77059fb31ea16b0a2e775312f166206d 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06095 77059fb31ea16b0a2e775312f166206d 38 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 38 1.0E-7 T 09-03-2017 L21SP3_RS06095 77059fb31ea16b0a2e775312f166206d 38 SUPERFAMILY SSF57840 1 38 3.66E-17 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS09080 23fb31705ca4935d9498762ea2c2af6c 366 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 25 348 1.8E-74 T 09-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 L21SP3_RS09080 23fb31705ca4935d9498762ea2c2af6c 366 SUPERFAMILY SSF111369 40 270 2.22E-29 T 09-03-2017 L21SP3_RS09080 23fb31705ca4935d9498762ea2c2af6c 366 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 51 266 1.3E-20 T 09-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain L21SP3_RS09080 23fb31705ca4935d9498762ea2c2af6c 366 Gene3D G3DSA:2.40.50.100 53 83 2.5E-12 T 09-03-2017 L21SP3_RS09080 23fb31705ca4935d9498762ea2c2af6c 366 Gene3D G3DSA:2.40.50.100 158 189 2.5E-12 T 09-03-2017 L21SP3_RS11135 3b0ee0adcc3139684586a8a10d4b1799 406 Gene3D G3DSA:3.40.50.2300 118 282 8.5E-24 T 09-03-2017 L21SP3_RS11135 3b0ee0adcc3139684586a8a10d4b1799 406 Gene3D G3DSA:1.10.10.60 342 389 6.3E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS11135 3b0ee0adcc3139684586a8a10d4b1799 406 Pfam PF12833 Helix-turn-helix domain 312 388 2.8E-15 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS11135 3b0ee0adcc3139684586a8a10d4b1799 406 Pfam PF13377 Periplasmic binding protein-like domain 118 281 8.7E-26 T 09-03-2017 L21SP3_RS11135 3b0ee0adcc3139684586a8a10d4b1799 406 SUPERFAMILY SSF53822 66 305 8.95E-26 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS11135 3b0ee0adcc3139684586a8a10d4b1799 406 Gene3D G3DSA:1.10.10.60 287 337 2.5E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS11135 3b0ee0adcc3139684586a8a10d4b1799 406 Gene3D G3DSA:3.40.50.2300 64 117 7.0E-6 T 09-03-2017 L21SP3_RS11135 3b0ee0adcc3139684586a8a10d4b1799 406 SMART SM00342 305 387 4.3E-21 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS11135 3b0ee0adcc3139684586a8a10d4b1799 406 SUPERFAMILY SSF46689 343 390 2.18E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS04630 dffabe16562c255e74a3d4e73103e6c3 360 Gene3D G3DSA:3.40.350.10 4 130 2.2E-19 T 09-03-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal L21SP3_RS04630 dffabe16562c255e74a3d4e73103e6c3 360 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 132 3.6E-16 T 09-03-2017 IPR000587 Creatinase, N-terminal GO:0016787 L21SP3_RS04630 dffabe16562c255e74a3d4e73103e6c3 360 SUPERFAMILY SSF55920 129 353 1.7E-73 T 09-03-2017 IPR000994 Peptidase M24, structural domain L21SP3_RS04630 dffabe16562c255e74a3d4e73103e6c3 360 Pfam PF00557 Metallopeptidase family M24 140 340 9.6E-65 T 09-03-2017 IPR000994 Peptidase M24, structural domain L21SP3_RS04630 dffabe16562c255e74a3d4e73103e6c3 360 Gene3D G3DSA:3.90.230.10 132 353 5.2E-75 T 09-03-2017 IPR000994 Peptidase M24, structural domain L21SP3_RS04630 dffabe16562c255e74a3d4e73103e6c3 360 SUPERFAMILY SSF53092 13 132 1.74E-18 T 09-03-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 SUPERFAMILY SSF81665 243 328 1.31E-13 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 SUPERFAMILY SSF81665 97 145 1.31E-13 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 Pfam PF00122 E1-E2 ATPase 113 325 9.4E-61 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 Pfam PF00702 haloacid dehalogenase-like hydrolase 334 547 3.4E-33 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 SUPERFAMILY SSF56784 334 352 1.88E-49 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 SUPERFAMILY SSF56784 391 633 1.88E-49 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 PRINTS PR00943 Copper-transporting ATPase signature 265 279 4.3E-5 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 PRINTS PR00943 Copper-transporting ATPase signature 568 582 4.3E-5 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 PRINTS PR00943 Copper-transporting ATPase signature 131 149 4.3E-5 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 PRINTS PR00943 Copper-transporting ATPase signature 510 527 4.3E-5 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 Gene3D G3DSA:3.40.50.1000 458 605 3.4E-39 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 336 342 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 192 206 3.9E-24 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 569 3.9E-24 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 552 3.9E-24 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 480 490 3.9E-24 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 334 348 3.9E-24 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 457 468 3.9E-24 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 Gene3D G3DSA:3.40.1110.10 348 457 7.9E-17 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 Gene3D G3DSA:2.70.150.10 99 242 3.5E-28 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 SUPERFAMILY SSF81653 148 242 2.09E-23 T 09-03-2017 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 91 636 9.4E-169 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 114 612 5.9E-77 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 L21SP3_RS02630 3daf1c65598e9a16eeadb7a5a82187cd 664 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 75 636 5.2E-122 T 09-03-2017 L21SP3_RS05145 3f089770550ac98dd6759e79767b6446 224 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 199 215 - T 09-03-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 L21SP3_RS05145 3f089770550ac98dd6759e79767b6446 224 PIRSF PIRSF001435 13 223 7.8E-50 T 09-03-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 L21SP3_RS05145 3f089770550ac98dd6759e79767b6446 224 Hamap MF_00942 Endonuclease III [nth]. 1 221 30.911 T 09-03-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 L21SP3_RS05145 3f089770550ac98dd6759e79767b6446 224 SMART SM00478 50 197 2.8E-54 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 L21SP3_RS05145 3f089770550ac98dd6759e79767b6446 224 SUPERFAMILY SSF48150 17 216 3.61E-63 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 L21SP3_RS05145 3f089770550ac98dd6759e79767b6446 224 Gene3D G3DSA:1.10.1670.10 135 217 3.1E-32 T 09-03-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 L21SP3_RS05145 3f089770550ac98dd6759e79767b6446 224 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 46 180 1.3E-25 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 L21SP3_RS05145 3f089770550ac98dd6759e79767b6446 224 Pfam PF00633 Helix-hairpin-helix motif 111 138 6.5E-7 T 09-03-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 L21SP3_RS05145 3f089770550ac98dd6759e79767b6446 224 Gene3D G3DSA:1.10.340.30 37 134 6.9E-34 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 L21SP3_RS09740 6d952b89c1f169e48dff372232b27192 301 SUPERFAMILY SSF53474 47 300 5.93E-44 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS09740 6d952b89c1f169e48dff372232b27192 301 Gene3D G3DSA:3.40.50.1820 43 285 1.1E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS09740 6d952b89c1f169e48dff372232b27192 301 Pfam PF00326 Prolyl oligopeptidase family 95 300 4.6E-18 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 L21SP3_RS09035 8d693edce3a8a1900841364338fa811b 611 SMART SM00729 261 483 9.1E-27 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP3_RS09035 8d693edce3a8a1900841364338fa811b 611 Pfam PF04055 Radical SAM superfamily 265 429 1.5E-20 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS09035 8d693edce3a8a1900841364338fa811b 611 SUPERFAMILY SSF102114 229 574 2.49E-38 T 09-03-2017 L21SP3_RS09035 8d693edce3a8a1900841364338fa811b 611 Gene3D G3DSA:3.80.30.20 260 468 6.2E-41 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe L21SP3_RS09035 8d693edce3a8a1900841364338fa811b 611 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 15 589 3.9E-184 T 09-03-2017 IPR023862 Conserved hypothetical protein CHP03960, radical SAM L21SP3_RS02100 ff6d0ae449503cc5c5f7f6f18a7bf3c2 489 SUPERFAMILY SSF52540 222 474 1.61E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02100 ff6d0ae449503cc5c5f7f6f18a7bf3c2 489 SMART SM00382 241 438 2.2E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS02100 ff6d0ae449503cc5c5f7f6f18a7bf3c2 489 Gene3D G3DSA:1.10.860.10 49 153 3.6E-28 T 09-03-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal L21SP3_RS02100 ff6d0ae449503cc5c5f7f6f18a7bf3c2 489 SUPERFAMILY SSF48024 46 161 6.93E-29 T 09-03-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 L21SP3_RS02100 ff6d0ae449503cc5c5f7f6f18a7bf3c2 489 Pfam PF03796 DnaB-like helicase C terminal domain 224 481 2.8E-111 T 09-03-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 L21SP3_RS02100 ff6d0ae449503cc5c5f7f6f18a7bf3c2 489 Pfam PF00772 DnaB-like helicase N terminal domain 48 152 6.6E-26 T 09-03-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 L21SP3_RS02100 ff6d0ae449503cc5c5f7f6f18a7bf3c2 489 Gene3D G3DSA:3.40.50.300 218 483 9.5E-103 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02100 ff6d0ae449503cc5c5f7f6f18a7bf3c2 489 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 49 483 6.6E-163 T 09-03-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 L21SP3_RS00980 da451d6dc184166256ae72d4becfa7f0 352 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 7 349 48.246 T 09-03-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 L21SP3_RS00980 da451d6dc184166256ae72d4becfa7f0 352 Gene3D G3DSA:3.90.1150.10 254 349 1.4E-23 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS00980 da451d6dc184166256ae72d4becfa7f0 352 Gene3D G3DSA:3.40.640.10 41 253 1.4E-55 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS00980 da451d6dc184166256ae72d4becfa7f0 352 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 347 3.1E-92 T 09-03-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 L21SP3_RS00980 da451d6dc184166256ae72d4becfa7f0 352 Pfam PF00155 Aminotransferase class I and II 28 345 4.2E-45 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 L21SP3_RS00980 da451d6dc184166256ae72d4becfa7f0 352 SUPERFAMILY SSF53383 9 347 1.53E-65 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS02815 efc89201e3e135afaca0aeea177b4073 728 SUPERFAMILY SSF75005 416 711 1.71E-60 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS02815 efc89201e3e135afaca0aeea177b4073 728 SUPERFAMILY SSF75005 67 326 2.58E-29 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS02815 efc89201e3e135afaca0aeea177b4073 728 Gene3D G3DSA:2.115.10.20 83 289 1.3E-27 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS02815 efc89201e3e135afaca0aeea177b4073 728 Pfam PF04616 Glycosyl hydrolases family 43 421 710 1.4E-57 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS02815 efc89201e3e135afaca0aeea177b4073 728 Pfam PF04616 Glycosyl hydrolases family 43 85 238 9.8E-12 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS02815 efc89201e3e135afaca0aeea177b4073 728 Gene3D G3DSA:2.115.10.20 417 723 1.8E-66 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS00310 f063eb158223bdadc1777a6749914fe4 290 Gene3D G3DSA:3.30.465.10 82 218 3.1E-31 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 L21SP3_RS00310 f063eb158223bdadc1777a6749914fe4 290 SUPERFAMILY SSF56176 14 197 9.35E-35 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 L21SP3_RS00310 f063eb158223bdadc1777a6749914fe4 290 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 16 289 2.1E-52 T 09-03-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS00310 f063eb158223bdadc1777a6749914fe4 290 Gene3D G3DSA:3.90.78.10 219 289 2.4E-22 T 09-03-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS00310 f063eb158223bdadc1777a6749914fe4 290 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 290 64.72 T 09-03-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS00310 f063eb158223bdadc1777a6749914fe4 290 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 194 288 2.1E-21 T 09-03-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS00310 f063eb158223bdadc1777a6749914fe4 290 SUPERFAMILY SSF56194 189 290 6.8E-26 T 09-03-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS00310 f063eb158223bdadc1777a6749914fe4 290 Gene3D G3DSA:3.30.43.10 14 77 2.5E-17 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 L21SP3_RS00310 f063eb158223bdadc1777a6749914fe4 290 Pfam PF01565 FAD binding domain 30 155 1.1E-18 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 L21SP3_RS05625 8b58ab50a01b15a81fd1278a313cddfe 179 TIGRFAM TIGR02989 Sig-70_gvs1: RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family 15 170 2.0E-40 T 09-03-2017 IPR014331 RNA polymerase sigma-70 ECF-like, Rhodopirellula baltica L21SP3_RS05625 8b58ab50a01b15a81fd1278a313cddfe 179 SUPERFAMILY SSF88946 9 100 3.92E-19 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS05625 8b58ab50a01b15a81fd1278a313cddfe 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 166 1.2E-21 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS05625 8b58ab50a01b15a81fd1278a313cddfe 179 Gene3D G3DSA:1.10.1740.10 9 111 5.9E-21 T 09-03-2017 L21SP3_RS05625 8b58ab50a01b15a81fd1278a313cddfe 179 Pfam PF04542 Sigma-70 region 2 22 86 1.9E-11 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS05625 8b58ab50a01b15a81fd1278a313cddfe 179 Pfam PF04545 Sigma-70, region 4 120 151 6.5E-6 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS05625 8b58ab50a01b15a81fd1278a313cddfe 179 SUPERFAMILY SSF88659 103 172 1.27E-8 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS05625 8b58ab50a01b15a81fd1278a313cddfe 179 Gene3D G3DSA:1.10.10.10 112 170 2.1E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 3 571 35.707 T 09-03-2017 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 SUPERFAMILY SSF55681 432 592 6.97E-107 T 09-03-2017 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 SUPERFAMILY SSF55681 118 297 6.97E-107 T 09-03-2017 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 Pfam PF01336 OB-fold nucleic acid binding domain 20 104 2.8E-14 T 09-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 593 5.1E-233 T 09-03-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 Pfam PF02938 GAD domain 313 413 3.7E-25 T 09-03-2017 IPR029351 GAD domain Reactome: R-HSA-379726 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 Gene3D G3DSA:3.30.1360.30 282 420 2.0E-41 T 09-03-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 PRINTS PR01042 Aspartyl-tRNA synthetase signature 195 207 6.8E-26 T 09-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 PRINTS PR01042 Aspartyl-tRNA synthetase signature 526 540 6.8E-26 T 09-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 PRINTS PR01042 Aspartyl-tRNA synthetase signature 212 225 6.8E-26 T 09-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 PRINTS PR01042 Aspartyl-tRNA synthetase signature 482 498 6.8E-26 T 09-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 SUPERFAMILY SSF55261 294 426 1.96E-36 T 09-03-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 SUPERFAMILY SSF50249 4 108 1.14E-29 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 Gene3D G3DSA:2.40.50.140 3 111 6.2E-33 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 Pfam PF00152 tRNA synthetases class II (D, K and N) 123 566 8.0E-107 T 09-03-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 Gene3D G3DSA:3.30.930.10 136 281 7.9E-115 T 09-03-2017 L21SP3_RS00105 ea0d289ebb0d1b59e71608645c18410d 603 Gene3D G3DSA:3.30.930.10 421 593 7.9E-115 T 09-03-2017 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 SMART SM00387 878 1002 3.2E-26 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 SMART SM00062 48 267 2.7E-30 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 SUPERFAMILY SSF55874 826 1000 1.24E-33 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 Gene3D G3DSA:3.30.450.20 307 426 2.5E-15 T 09-03-2017 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 SUPERFAMILY SSF53850 49 264 8.36E-48 T 09-03-2017 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 SUPERFAMILY SSF55781 422 622 2.42E-9 T 09-03-2017 IPR029016 GAF domain-like L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 SUPERFAMILY SSF55785 306 427 2.42E-14 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 SMART SM00091 637 703 2.2E-4 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 SMART SM00091 318 381 2.4 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 Pfam PF00512 His Kinase A (phospho-acceptor) domain 771 834 1.5E-9 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 PRINTS PR00344 Bacterial sensor protein C-terminal signature 931 945 3.2E-16 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 PRINTS PR00344 Bacterial sensor protein C-terminal signature 986 999 3.2E-16 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 PRINTS PR00344 Bacterial sensor protein C-terminal signature 962 980 3.2E-16 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 PRINTS PR00344 Bacterial sensor protein C-terminal signature 949 959 3.2E-16 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 Gene3D G3DSA:3.30.450.20 637 776 8.2E-14 T 09-03-2017 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 SMART SM00388 771 837 3.2E-10 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 Gene3D G3DSA:3.30.565.10 824 1004 9.2E-38 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 Gene3D G3DSA:3.30.450.40 427 636 6.2E-20 T 09-03-2017 IPR029016 GAF domain-like L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 SUPERFAMILY SSF55785 624 747 1.43E-12 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 SUPERFAMILY SSF47384 765 834 3.14E-11 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 264 1.8E-43 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 878 1000 6.4E-19 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 Gene3D G3DSA:3.40.190.10 227 266 2.8E-25 T 09-03-2017 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 Gene3D G3DSA:3.40.190.10 45 124 2.8E-25 T 09-03-2017 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 633 755 1.6E-15 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 316 436 7.2E-16 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 Gene3D G3DSA:3.40.190.10 125 224 2.1E-16 T 09-03-2017 L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 Pfam PF13426 PAS domain 653 748 2.5E-8 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 Pfam PF13426 PAS domain 330 427 1.2E-5 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01720 cc7de3a5e7285818806b405200568cd1 1006 Gene3D G3DSA:1.10.287.130 777 823 5.7E-7 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS05945 2cab184c0cbae0fc46a881c466806be5 280 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 3 23 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS05945 2cab184c0cbae0fc46a881c466806be5 280 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 21 7.1E-4 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS00430 bc89f7305cf0d57e4304d4fff5b85b5a 171 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 10 154 9.9E-35 T 09-03-2017 IPR011605 NusB antitermination factor GO:0006353 L21SP3_RS00430 bc89f7305cf0d57e4304d4fff5b85b5a 171 Gene3D G3DSA:1.10.940.10 10 160 5.2E-38 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 L21SP3_RS00430 bc89f7305cf0d57e4304d4fff5b85b5a 171 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 2 156 20.665 T 09-03-2017 IPR011605 NusB antitermination factor GO:0006353 L21SP3_RS00430 bc89f7305cf0d57e4304d4fff5b85b5a 171 Pfam PF01029 NusB family 12 153 2.0E-34 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 L21SP3_RS00430 bc89f7305cf0d57e4304d4fff5b85b5a 171 SUPERFAMILY SSF48013 9 157 2.09E-33 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 L21SP3_RS10855 a1d8dfa35e7276def4ce7f429c19375d 372 SUPERFAMILY SSF53822 142 371 9.85E-42 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS10855 a1d8dfa35e7276def4ce7f429c19375d 372 Pfam PF13377 Periplasmic binding protein-like domain 215 371 1.6E-29 T 09-03-2017 L21SP3_RS10855 a1d8dfa35e7276def4ce7f429c19375d 372 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 79 4.6E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP3_RS10855 a1d8dfa35e7276def4ce7f429c19375d 372 SUPERFAMILY SSF46785 12 83 1.89E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS10855 a1d8dfa35e7276def4ce7f429c19375d 372 Gene3D G3DSA:1.10.10.10 13 84 4.4E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS10855 a1d8dfa35e7276def4ce7f429c19375d 372 Gene3D G3DSA:3.40.50.2300 87 213 5.4E-11 T 09-03-2017 L21SP3_RS10855 a1d8dfa35e7276def4ce7f429c19375d 372 SMART SM00345 20 79 3.3E-13 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP3_RS10855 a1d8dfa35e7276def4ce7f429c19375d 372 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 2.3E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP3_RS10855 a1d8dfa35e7276def4ce7f429c19375d 372 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 2.3E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP3_RS10855 a1d8dfa35e7276def4ce7f429c19375d 372 Gene3D G3DSA:3.40.50.2300 214 371 2.5E-38 T 09-03-2017 L21SP3_RS08805 d2051a6a3a1d0bafde83e0d9add49f87 327 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 28 108 6.1E-17 T 09-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 L21SP3_RS08805 d2051a6a3a1d0bafde83e0d9add49f87 327 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 25 320 53.187 T 09-03-2017 IPR023009 Tyrosine recombinase XerC/XerD L21SP3_RS08805 d2051a6a3a1d0bafde83e0d9add49f87 327 Gene3D G3DSA:1.10.443.10 132 313 9.9E-51 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP3_RS08805 d2051a6a3a1d0bafde83e0d9add49f87 327 SUPERFAMILY SSF56349 26 312 1.5E-50 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 L21SP3_RS08805 d2051a6a3a1d0bafde83e0d9add49f87 327 Pfam PF00589 Phage integrase family 132 305 7.4E-41 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP3_RS08805 d2051a6a3a1d0bafde83e0d9add49f87 327 Gene3D G3DSA:1.10.150.130 25 119 2.8E-23 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal L21SP3_RS03285 d02463d823e9ff52e47bcee46eef219d 364 Pfam PF07687 Peptidase dimerisation domain 168 270 1.6E-26 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain L21SP3_RS03285 d02463d823e9ff52e47bcee46eef219d 364 Gene3D G3DSA:3.30.70.360 181 275 1.3E-29 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain L21SP3_RS03285 d02463d823e9ff52e47bcee46eef219d 364 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 62 71 - T 09-03-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 L21SP3_RS03285 d02463d823e9ff52e47bcee46eef219d 364 Gene3D G3DSA:3.40.630.10 2 180 3.0E-61 T 09-03-2017 L21SP3_RS03285 d02463d823e9ff52e47bcee46eef219d 364 Gene3D G3DSA:3.40.630.10 302 360 3.0E-61 T 09-03-2017 L21SP3_RS03285 d02463d823e9ff52e47bcee46eef219d 364 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 3 348 5.4E-67 T 09-03-2017 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase L21SP3_RS03285 d02463d823e9ff52e47bcee46eef219d 364 SUPERFAMILY SSF55031 172 278 2.84E-24 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain L21SP3_RS03285 d02463d823e9ff52e47bcee46eef219d 364 Pfam PF01546 Peptidase family M20/M25/M40 63 357 1.3E-34 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 L21SP3_RS03285 d02463d823e9ff52e47bcee46eef219d 364 SUPERFAMILY SSF53187 284 360 7.43E-53 T 09-03-2017 L21SP3_RS03285 d02463d823e9ff52e47bcee46eef219d 364 SUPERFAMILY SSF53187 2 171 7.43E-53 T 09-03-2017 L21SP3_RS07355 a37b5b0ded1c4a561140979492f68b19 137 Gene3D G3DSA:1.10.1220.10 3 47 3.3E-19 T 09-03-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 L21SP3_RS07355 a37b5b0ded1c4a561140979492f68b19 137 SUPERFAMILY SSF47598 2 47 3.11E-10 T 09-03-2017 IPR010985 Ribbon-helix-helix GO:0006355 L21SP3_RS07355 a37b5b0ded1c4a561140979492f68b19 137 Hamap MF_00476 Putative nickel-responsive regulator [nikR]. 3 133 26.382 T 09-03-2017 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 L21SP3_RS07355 a37b5b0ded1c4a561140979492f68b19 137 Pfam PF08753 NikR C terminal nickel binding domain 55 130 9.9E-29 T 09-03-2017 IPR014864 Transcription factor, NikR, nickel binding C-terminal L21SP3_RS07355 a37b5b0ded1c4a561140979492f68b19 137 SUPERFAMILY SSF55021 53 134 7.78E-24 T 09-03-2017 L21SP3_RS07355 a37b5b0ded1c4a561140979492f68b19 137 Gene3D G3DSA:3.30.70.1150 52 133 8.7E-31 T 09-03-2017 L21SP3_RS07355 a37b5b0ded1c4a561140979492f68b19 137 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 43 1.2E-8 T 09-03-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 L21SP3_RS11180 6197a6fc6347d1f157192ea7d7d2c3fe 383 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 22 376 7.6E-162 T 09-03-2017 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 L21SP3_RS11180 6197a6fc6347d1f157192ea7d7d2c3fe 383 PIRSF PIRSF015658 4 382 1.1E-171 T 09-03-2017 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 L21SP3_RS11180 6197a6fc6347d1f157192ea7d7d2c3fe 383 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 23 380 5.1E-159 T 09-03-2017 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 PRINTS PR00097 Anthranilate synthase component II signature 47 56 2.4E-35 T 09-03-2017 L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 PRINTS PR00097 Anthranilate synthase component II signature 164 177 2.4E-35 T 09-03-2017 L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.4E-35 T 09-03-2017 L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 PRINTS PR00097 Anthranilate synthase component II signature 99 107 2.4E-35 T 09-03-2017 L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 PRINTS PR00097 Anthranilate synthase component II signature 119 131 2.4E-35 T 09-03-2017 L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 PRINTS PR00097 Anthranilate synthase component II signature 74 85 2.4E-35 T 09-03-2017 L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 6.0E-75 T 09-03-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 3.6E-15 T 09-03-2017 L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 3.6E-15 T 09-03-2017 L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 3.6E-15 T 09-03-2017 L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 Pfam PF00117 Glutamine amidotransferase class-I 3 186 6.6E-58 T 09-03-2017 IPR017926 Glutamine amidotransferase L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.5E-8 T 09-03-2017 L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 2.5E-8 T 09-03-2017 L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 SUPERFAMILY SSF52317 1 188 5.11E-56 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS01050 7bbea4606ecec2fb231409b3240bd282 206 Gene3D G3DSA:3.40.50.880 1 188 8.5E-69 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS08630 22725682f3392a8ed901fef476fa083f 1278 Gene3D G3DSA:1.20.1270.50 310 406 7.1E-15 T 09-03-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 L21SP3_RS08630 22725682f3392a8ed901fef476fa083f 1278 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 34 292 2.0E-40 T 09-03-2017 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 L21SP3_RS08630 22725682f3392a8ed901fef476fa083f 1278 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 413 826 2.0E-49 T 09-03-2017 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 L21SP3_RS08630 22725682f3392a8ed901fef476fa083f 1278 SUPERFAMILY SSF88688 310 405 1.73E-17 T 09-03-2017 IPR028995 Glycoside hydrolase families 57/38, central domain L21SP3_RS08630 22725682f3392a8ed901fef476fa083f 1278 Gene3D G3DSA:3.20.110.10 29 265 1.5E-52 T 09-03-2017 IPR027291 Glycoside hydrolase 38/57, N-terminal domain L21SP3_RS08630 22725682f3392a8ed901fef476fa083f 1278 SUPERFAMILY SSF74650 407 849 7.53E-68 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP3_RS08630 22725682f3392a8ed901fef476fa083f 1278 SMART SM00872 306 383 7.0E-21 T 09-03-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 L21SP3_RS08630 22725682f3392a8ed901fef476fa083f 1278 Gene3D G3DSA:2.60.40.1180 408 514 5.3E-8 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta L21SP3_RS08630 22725682f3392a8ed901fef476fa083f 1278 Pfam PF09261 Alpha mannosidase middle domain 310 377 6.1E-16 T 09-03-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 L21SP3_RS08630 22725682f3392a8ed901fef476fa083f 1278 SUPERFAMILY SSF88713 29 220 8.9E-46 T 09-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 L21SP3_RS07495 21a65dd32f30d0d9aa2ffa96f3f8868f 1022 SUPERFAMILY SSF56436 32 274 1.11E-62 T 09-03-2017 IPR016187 C-type lectin fold L21SP3_RS07495 21a65dd32f30d0d9aa2ffa96f3f8868f 1022 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 849 985 9.1E-19 T 09-03-2017 L21SP3_RS07495 21a65dd32f30d0d9aa2ffa96f3f8868f 1022 SUPERFAMILY SSF50939 329 673 6.17E-27 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS07495 21a65dd32f30d0d9aa2ffa96f3f8868f 1022 Pfam PF03781 Sulfatase-modifying factor enzyme 1 35 274 1.6E-51 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS07495 21a65dd32f30d0d9aa2ffa96f3f8868f 1022 Pfam PF13088 BNR repeat-like domain 345 634 1.3E-17 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS07495 21a65dd32f30d0d9aa2ffa96f3f8868f 1022 Gene3D G3DSA:3.90.1580.10 28 277 1.2E-65 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS07495 21a65dd32f30d0d9aa2ffa96f3f8868f 1022 Gene3D G3DSA:2.120.10.10 329 674 5.2E-35 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS07495 21a65dd32f30d0d9aa2ffa96f3f8868f 1022 SUPERFAMILY SSF49899 774 991 3.17E-23 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS07495 21a65dd32f30d0d9aa2ffa96f3f8868f 1022 Gene3D G3DSA:2.60.120.200 779 990 5.9E-21 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS07495 21a65dd32f30d0d9aa2ffa96f3f8868f 1022 ProSitePatterns PS00018 EF-hand calcium-binding domain. 997 1009 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 445 674 4.8E-67 T 09-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 SUPERFAMILY SSF82866 1003 1198 5.75E-35 T 09-03-2017 L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 323 680 3.6E-93 T 09-03-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 705 1203 24.645 T 09-03-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 696 32.155 T 09-03-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 SUPERFAMILY SSF82866 489 685 4.58E-43 T 09-03-2017 L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 Pfam PF02355 Protein export membrane protein 517 684 6.2E-20 T 09-03-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 Pfam PF02355 Protein export membrane protein 1008 1197 6.3E-52 T 09-03-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 913 1192 4.1E-57 T 09-03-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 Gene3D G3DSA:1.20.1640.10 497 684 4.2E-28 T 09-03-2017 L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 Gene3D G3DSA:1.20.1640.10 1020 1206 3.6E-25 T 09-03-2017 L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 PRINTS PR01755 Bacterial translocase SecF protein signature 1140 1155 2.0E-18 T 09-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 PRINTS PR01755 Bacterial translocase SecF protein signature 1109 1127 2.0E-18 T 09-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial L21SP3_RS10415 fcf77d163eff99d67798607cb3c39de3 1209 PRINTS PR01755 Bacterial translocase SecF protein signature 733 748 2.0E-18 T 09-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial L21SP3_RS04010 2b2897eb9f38c42103c79c71e206f444 320 Gene3D G3DSA:3.40.50.620 2 198 3.1E-80 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS04010 2b2897eb9f38c42103c79c71e206f444 320 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 189 199 3.6E-23 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 L21SP3_RS04010 2b2897eb9f38c42103c79c71e206f444 320 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 63 82 3.6E-23 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 L21SP3_RS04010 2b2897eb9f38c42103c79c71e206f444 320 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 138 159 3.6E-23 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 L21SP3_RS04010 2b2897eb9f38c42103c79c71e206f444 320 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 13 29 3.6E-23 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 L21SP3_RS04010 2b2897eb9f38c42103c79c71e206f444 320 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 318 9.3E-96 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 L21SP3_RS04010 2b2897eb9f38c42103c79c71e206f444 320 Gene3D G3DSA:1.10.240.10 199 287 3.6E-34 T 09-03-2017 L21SP3_RS04010 2b2897eb9f38c42103c79c71e206f444 320 Pfam PF00579 tRNA synthetases class I (W and Y) 2 275 3.9E-64 T 09-03-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS04010 2b2897eb9f38c42103c79c71e206f444 320 SUPERFAMILY SSF52374 2 319 1.02E-93 T 09-03-2017 L21SP3_RS04010 2b2897eb9f38c42103c79c71e206f444 320 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 320 37.469 T 09-03-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 L21SP3_RS04010 2b2897eb9f38c42103c79c71e206f444 320 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 18 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SUPERFAMILY SSF55785 1106 1229 2.62E-9 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Pfam PF00072 Response regulator receiver domain 1503 1610 1.1E-12 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00448 1499 1610 4.2E-13 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1363 1479 6.4E-26 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Pfam PF08448 PAS fold 877 979 8.9E-13 T 09-03-2017 IPR013656 PAS fold-4 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SUPERFAMILY SSF47384 1236 1317 5.49E-20 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 283 401 6.0E-17 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 613 739 1.3E-10 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 867 981 4.8E-21 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 986 1115 6.3E-19 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SUPERFAMILY SSF55785 599 729 4.19E-19 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Pfam PF13426 PAS domain 1133 1230 0.57 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Pfam PF13426 PAS domain 302 398 2.6E-10 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00086 692 734 0.0026 T 09-03-2017 IPR001610 PAC motif L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00086 357 399 0.019 T 09-03-2017 IPR001610 PAC motif L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00086 108 150 0.1 T 09-03-2017 IPR001610 PAC motif L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00086 941 978 190.0 T 09-03-2017 IPR001610 PAC motif L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00086 820 858 420.0 T 09-03-2017 IPR001610 PAC motif L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00086 1067 1109 0.044 T 09-03-2017 IPR001610 PAC motif L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Gene3D G3DSA:1.10.287.130 1256 1312 9.1E-14 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SUPERFAMILY SSF55785 731 856 1.71E-8 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Pfam PF00989 PAS fold 620 731 1.6E-12 T 09-03-2017 IPR013767 PAS fold GO:0006355 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Pfam PF00989 PAS fold 995 1106 9.0E-13 T 09-03-2017 IPR013767 PAS fold GO:0006355 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1251 1316 2.6E-15 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00387 1362 1480 3.7E-35 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SUPERFAMILY SSF55785 18 148 2.9E-12 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Gene3D G3DSA:3.30.450.20 582 624 1.1E-4 T 09-03-2017 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Gene3D G3DSA:3.30.450.20 1215 1255 4.1E-8 T 09-03-2017 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Gene3D G3DSA:3.30.565.10 1317 1480 1.1E-39 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SUPERFAMILY SSF55785 270 397 2.26E-21 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Pfam PF08447 PAS fold 56 143 1.1E-11 T 09-03-2017 IPR013655 PAS fold-3 GO:0005515 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Pfam PF08447 PAS fold 769 846 6.8E-6 T 09-03-2017 IPR013655 PAS fold-3 GO:0005515 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00388 1251 1316 2.7E-20 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00091 509 576 68.0 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00091 285 351 4.5E-9 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00091 1121 1193 250.0 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00091 615 681 2.9E-5 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00091 33 100 17.0 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00091 990 1056 5.7E-8 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SMART SM00091 870 936 3.4E-11 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SUPERFAMILY SSF55874 1305 1480 1.03E-39 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SUPERFAMILY SSF55785 166 276 4.57E-5 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Gene3D G3DSA:3.40.50.2300 1495 1615 1.5E-20 T 09-03-2017 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SUPERFAMILY SSF55785 975 1107 4.36E-23 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Gene3D G3DSA:3.30.450.20 278 397 2.1E-21 T 09-03-2017 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Gene3D G3DSA:3.30.450.20 976 1106 5.4E-23 T 09-03-2017 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SUPERFAMILY SSF52172 1497 1616 7.12E-21 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Gene3D G3DSA:3.30.450.20 154 277 6.6E-13 T 09-03-2017 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Gene3D G3DSA:3.30.450.20 3 153 2.3E-22 T 09-03-2017 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Gene3D G3DSA:3.30.450.20 725 861 4.3E-19 T 09-03-2017 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Gene3D G3DSA:3.30.450.20 1107 1214 2.1E-9 T 09-03-2017 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Gene3D G3DSA:3.30.450.20 862 975 1.9E-27 T 09-03-2017 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1440 1458 6.1E-15 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1405 1419 6.1E-15 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1464 1477 6.1E-15 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1423 1433 6.1E-15 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 SUPERFAMILY SSF55785 855 976 1.18E-25 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10445 e966296196eeb2aaf69d42b1ccec0125 1719 Gene3D G3DSA:3.30.450.20 625 724 2.4E-19 T 09-03-2017 L21SP3_RS06820 58966562e9f9f94c313d6bba6310c316 340 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 23 330 6.9E-56 T 09-03-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS06820 58966562e9f9f94c313d6bba6310c316 340 Pfam PF01687 Riboflavin kinase 194 330 2.2E-25 T 09-03-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 L21SP3_RS06820 58966562e9f9f94c313d6bba6310c316 340 SUPERFAMILY SSF82114 184 333 2.62E-28 T 09-03-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 L21SP3_RS06820 58966562e9f9f94c313d6bba6310c316 340 SMART SM00904 192 331 1.6E-28 T 09-03-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 L21SP3_RS06820 58966562e9f9f94c313d6bba6310c316 340 Gene3D G3DSA:3.40.50.620 9 188 8.4E-48 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS06820 58966562e9f9f94c313d6bba6310c316 340 Pfam PF06574 FAD synthetase 16 174 1.5E-38 T 09-03-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS06820 58966562e9f9f94c313d6bba6310c316 340 Gene3D G3DSA:2.40.30.30 189 335 9.3E-28 T 09-03-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 L21SP3_RS06820 58966562e9f9f94c313d6bba6310c316 340 PIRSF PIRSF004491 6 337 3.2E-76 T 09-03-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS06820 58966562e9f9f94c313d6bba6310c316 340 SUPERFAMILY SSF52374 21 184 6.48E-27 T 09-03-2017 L21SP3_RS11095 c015e8c34137ed9edc3653d103f7f797 771 Hamap MF_00983 Probable primosomal protein N' [priA]. 23 770 22.63 T 09-03-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 L21SP3_RS11095 c015e8c34137ed9edc3653d103f7f797 771 SUPERFAMILY SSF52540 538 675 2.26E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11095 c015e8c34137ed9edc3653d103f7f797 771 SUPERFAMILY SSF52540 247 297 2.26E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11095 c015e8c34137ed9edc3653d103f7f797 771 SMART SM00490 535 631 3.3E-10 T 09-03-2017 IPR001650 Helicase, C-terminal L21SP3_RS11095 c015e8c34137ed9edc3653d103f7f797 771 TIGRFAM TIGR00595 priA: primosomal protein N' 249 769 3.9E-166 T 09-03-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 L21SP3_RS11095 c015e8c34137ed9edc3653d103f7f797 771 SUPERFAMILY SSF52540 211 390 5.14E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11095 c015e8c34137ed9edc3653d103f7f797 771 Gene3D G3DSA:3.40.50.300 506 675 3.2E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11095 c015e8c34137ed9edc3653d103f7f797 771 SMART SM00487 220 407 4.8E-19 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain L21SP3_RS11095 c015e8c34137ed9edc3653d103f7f797 771 Pfam PF00270 DEAD/DEAH box helicase 227 388 1.0E-16 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 L21SP3_RS11095 c015e8c34137ed9edc3653d103f7f797 771 Pfam PF00271 Helicase conserved C-terminal domain 541 630 1.4E-9 T 09-03-2017 IPR001650 Helicase, C-terminal L21SP3_RS11095 c015e8c34137ed9edc3653d103f7f797 771 Gene3D G3DSA:3.40.50.300 215 398 1.1E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00395 de71f95a8d391672ca553a4f99d4abaa 1509 SUPERFAMILY SSF51011 1123 1213 8.99E-6 T 09-03-2017 L21SP3_RS00395 de71f95a8d391672ca553a4f99d4abaa 1509 Gene3D G3DSA:2.60.120.200 86 261 2.6E-14 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00395 de71f95a8d391672ca553a4f99d4abaa 1509 Gene3D G3DSA:2.60.120.200 543 621 7.8E-4 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00395 de71f95a8d391672ca553a4f99d4abaa 1509 Pfam PF04616 Glycosyl hydrolases family 43 1263 1462 6.8E-10 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS00395 de71f95a8d391672ca553a4f99d4abaa 1509 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 1037 1207 6.1E-12 T 09-03-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 L21SP3_RS00395 de71f95a8d391672ca553a4f99d4abaa 1509 SUPERFAMILY SSF49899 513 627 1.46E-8 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00395 de71f95a8d391672ca553a4f99d4abaa 1509 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 91 257 3.2E-12 T 09-03-2017 L21SP3_RS00395 de71f95a8d391672ca553a4f99d4abaa 1509 Gene3D G3DSA:2.115.10.20 1263 1495 3.3E-28 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS00395 de71f95a8d391672ca553a4f99d4abaa 1509 SUPERFAMILY SSF49899 72 260 1.19E-13 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00395 de71f95a8d391672ca553a4f99d4abaa 1509 Pfam PF06439 Domain of Unknown Function (DUF1080) 493 639 3.7E-11 T 09-03-2017 IPR010496 Domain of unknown function DUF1080 L21SP3_RS00395 de71f95a8d391672ca553a4f99d4abaa 1509 SUPERFAMILY SSF75005 1264 1498 9.67E-33 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS00395 de71f95a8d391672ca553a4f99d4abaa 1509 SUPERFAMILY SSF51445 771 1108 2.11E-60 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS00395 de71f95a8d391672ca553a4f99d4abaa 1509 SMART SM00813 1035 1207 3.7E-7 T 09-03-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 272 331 1.0E-11 T 09-03-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 31 229 1.2E-23 T 09-03-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 330 34.943 T 09-03-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 SUPERFAMILY SSF55257 181 233 2.35E-29 T 09-03-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 SUPERFAMILY SSF55257 9 55 2.35E-29 T 09-03-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 258 322 1.5E-20 T 09-03-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 SUPERFAMILY SSF47789 264 331 3.14E-21 T 09-03-2017 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 Gene3D G3DSA:3.30.1360.10 14 66 9.9E-12 T 09-03-2017 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 SUPERFAMILY SSF56553 55 180 2.35E-37 T 09-03-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 61 156 2.5E-23 T 09-03-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 Gene3D G3DSA:2.170.120.12 67 179 3.4E-40 T 09-03-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 25 330 1.0E-109 T 09-03-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 Gene3D G3DSA:1.10.150.20 258 330 6.7E-26 T 09-03-2017 L21SP3_RS06080 3c2e9dbdb005bdfe32da9a8594f4edf7 331 SMART SM00662 25 236 4.3E-80 T 09-03-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS04155 f13146375b80abbbb87c1b14579e9e47 325 SMART SM00471 158 295 0.0037 T 09-03-2017 IPR003607 HD/PDEase domain L21SP3_RS04155 f13146375b80abbbb87c1b14579e9e47 325 SUPERFAMILY SSF109604 144 286 4.71E-9 T 09-03-2017 L21SP3_RS04155 f13146375b80abbbb87c1b14579e9e47 325 Pfam PF01336 OB-fold nucleic acid binding domain 37 91 5.6E-8 T 09-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 L21SP3_RS04155 f13146375b80abbbb87c1b14579e9e47 325 Pfam PF01966 HD domain 163 285 3.7E-5 T 09-03-2017 IPR006674 HD domain L21SP3_RS04155 f13146375b80abbbb87c1b14579e9e47 325 Gene3D G3DSA:2.40.50.140 26 93 2.5E-5 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04155 f13146375b80abbbb87c1b14579e9e47 325 SUPERFAMILY SSF50249 26 94 6.85E-5 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04385 65a76f987ea073a2b21c13873a7dd1c4 416 Gene3D G3DSA:3.90.1150.10 277 409 1.9E-54 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS04385 65a76f987ea073a2b21c13873a7dd1c4 416 SUPERFAMILY SSF53383 2 409 1.26E-168 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS04385 65a76f987ea073a2b21c13873a7dd1c4 416 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 216 232 - T 09-03-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 L21SP3_RS04385 65a76f987ea073a2b21c13873a7dd1c4 416 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 1 409 49.313 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 L21SP3_RS04385 65a76f987ea073a2b21c13873a7dd1c4 416 Pfam PF00464 Serine hydroxymethyltransferase 3 378 3.3E-162 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 L21SP3_RS04385 65a76f987ea073a2b21c13873a7dd1c4 416 Gene3D G3DSA:3.40.640.10 31 276 3.9E-97 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS04385 65a76f987ea073a2b21c13873a7dd1c4 416 PIRSF PIRSF000412 1 413 3.0E-173 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 85 123 1.6E-14 T 09-03-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 SUPERFAMILY SSF53920 190 570 2.62E-130 T 09-03-2017 IPR009016 Iron hydrogenase L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 Gene3D G3DSA:3.40.30.10 596 645 1.9E-10 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 SUPERFAMILY SSF52833 587 664 3.13E-12 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 Gene3D G3DSA:3.10.20.30 8 59 3.0E-5 T 09-03-2017 IPR012675 Beta-grasp domain L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 Pfam PF12838 4Fe-4S dicluster domain 147 204 6.8E-7 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 34 51 - T 09-03-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 148 159 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 7 78 1.6E-14 T 09-03-2017 L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 SMART SM00929 85 125 1.5E-13 T 09-03-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 SUPERFAMILY SSF54862 77 215 1.55E-35 T 09-03-2017 L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 191 202 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 224 508 1.8E-96 T 09-03-2017 IPR004108 Iron hydrogenase, large subunit, C-terminal L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 587 662 2.1E-9 T 09-03-2017 L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 141 511 3.5E-151 T 09-03-2017 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 SUPERFAMILY SSF54292 7 75 1.71E-17 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 SMART SM00902 513 573 3.9E-19 T 09-03-2017 IPR003149 Iron hydrogenase, small subunit L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 Gene3D G3DSA:3.30.70.20 95 196 1.4E-13 T 09-03-2017 L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 Gene3D G3DSA:4.10.260.20 515 595 7.8E-24 T 09-03-2017 IPR003149 Iron hydrogenase, small subunit L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 Pfam PF02256 Iron hydrogenase small subunit 517 572 1.4E-19 T 09-03-2017 IPR003149 Iron hydrogenase, small subunit L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 Gene3D G3DSA:3.40.50.1780 301 430 2.6E-72 T 09-03-2017 L21SP3_RS06440 ecf5fa7a86b73f62e09a3ba4f4adfad7 672 Gene3D G3DSA:3.40.50.1780 197 249 2.6E-72 T 09-03-2017 L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 Gene3D G3DSA:3.40.50.300 5 53 4.1E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 Gene3D G3DSA:3.40.50.300 822 942 2.3E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 Gene3D G3DSA:3.40.50.300 604 674 2.3E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 Gene3D G3DSA:3.40.50.300 480 598 4.1E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 SUPERFAMILY SSF52540 6 206 4.12E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 SUPERFAMILY SSF52540 432 571 4.12E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 Gene3D G3DSA:1.20.1580.10 695 821 5.4E-55 T 09-03-2017 L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 941 21.641 T 09-03-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 SUPERFAMILY SSF52540 617 914 1.77E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 Gene3D G3DSA:3.30.1490.20 132 155 1.3E-23 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 Gene3D G3DSA:3.30.1490.20 202 243 1.3E-23 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 ProSitePatterns PS00211 ABC transporters family signature. 831 845 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 Gene3D G3DSA:1.10.8.280 295 408 3.6E-28 T 09-03-2017 L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 Gene3D G3DSA:1.20.1580.10 409 479 1.9E-52 T 09-03-2017 L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 Gene3D G3DSA:1.20.1580.10 93 131 1.9E-52 T 09-03-2017 L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 Gene3D G3DSA:1.20.1580.10 260 293 1.9E-52 T 09-03-2017 L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 6 926 0.0 T 09-03-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 L21SP3_RS06765 762085208a8a33823d5e8448a41d04fd 951 Pfam PF00005 ABC transporter 625 861 5.0E-9 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS10420 ca2e8cd8298698b2f62ab8684b3f348d 154 Pfam PF01476 LysM domain 102 150 1.0E-9 T 09-03-2017 IPR018392 LysM domain L21SP3_RS10420 ca2e8cd8298698b2f62ab8684b3f348d 154 SUPERFAMILY SSF54106 100 150 1.02E-6 T 09-03-2017 IPR018392 LysM domain L21SP3_RS10420 ca2e8cd8298698b2f62ab8684b3f348d 154 SMART SM00257 101 150 3.1E-10 T 09-03-2017 IPR018392 LysM domain L21SP3_RS10420 ca2e8cd8298698b2f62ab8684b3f348d 154 Gene3D G3DSA:3.10.350.10 100 151 9.4E-11 T 09-03-2017 IPR018392 LysM domain L21SP3_RS02495 b86778896042b918b3ff71ba0666f968 225 SMART SM00563 46 157 1.6E-28 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 L21SP3_RS02495 b86778896042b918b3ff71ba0666f968 225 SUPERFAMILY SSF69593 10 209 1.7E-45 T 09-03-2017 L21SP3_RS02495 b86778896042b918b3ff71ba0666f968 225 Gene3D G3DSA:3.40.1130.10 8 208 3.4E-32 T 09-03-2017 L21SP3_RS02495 b86778896042b918b3ff71ba0666f968 225 Pfam PF01553 Acyltransferase 31 154 1.4E-22 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Gene3D G3DSA:1.10.287.130 1033 1090 3.9E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1193 1207 1.0E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1252 1265 1.0E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1228 1246 1.0E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Gene3D G3DSA:3.30.450.20 658 774 1.7E-9 T 09-03-2017 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Gene3D G3DSA:3.30.450.20 895 1018 2.0E-13 T 09-03-2017 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SUPERFAMILY SSF55874 1094 1265 1.02E-41 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1151 1267 2.2E-23 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SUPERFAMILY SSF158472 240 279 7.45E-5 T 09-03-2017 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Gene3D G3DSA:3.30.450.20 540 657 3.3E-6 T 09-03-2017 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Gene3D G3DSA:3.30.450.20 396 536 1.0E-16 T 09-03-2017 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 666 788 2.4E-12 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 903 1027 5.4E-14 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 282 405 6.8E-9 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 795 903 4.5E-16 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Gene3D G3DSA:3.30.450.20 275 395 8.0E-12 T 09-03-2017 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SUPERFAMILY SSF55785 918 1028 7.03E-12 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SMART SM00387 1150 1268 2.0E-31 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SUPERFAMILY SSF52172 1289 1407 1.99E-25 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SMART SM00086 358 400 190.0 T 09-03-2017 IPR001610 PAC motif L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SMART SM00086 979 1020 6.4 T 09-03-2017 IPR001610 PAC motif L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SMART SM00086 856 897 11.0 T 09-03-2017 IPR001610 PAC motif L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SMART SM00086 486 529 260.0 T 09-03-2017 IPR001610 PAC motif L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SMART SM00086 620 657 130.0 T 09-03-2017 IPR001610 PAC motif L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Pfam PF13426 PAS domain 293 396 1.8E-5 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Pfam PF13426 PAS domain 681 772 1.1E-4 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Pfam PF13426 PAS domain 802 896 2.7E-11 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Pfam PF13426 PAS domain 918 1019 2.9E-8 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SUPERFAMILY SSF55785 275 396 5.58E-9 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Gene3D G3DSA:3.40.50.2300 1289 1407 1.8E-24 T 09-03-2017 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Pfam PF00072 Response regulator receiver domain 1294 1401 3.0E-14 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SUPERFAMILY SSF47384 1025 1106 2.94E-20 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SUPERFAMILY SSF55785 401 527 2.62E-7 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Gene3D G3DSA:3.30.450.20 785 894 1.3E-16 T 09-03-2017 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SUPERFAMILY SSF55785 654 777 4.64E-9 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1040 1104 4.6E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SUPERFAMILY SSF55785 793 897 2.44E-16 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SMART SM00388 1040 1105 5.7E-20 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SMART SM00448 1291 1402 1.2E-17 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SMART SM00091 789 854 0.0022 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SMART SM00091 669 734 0.13 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SMART SM00091 412 481 42.0 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SMART SM00091 905 974 2.3 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 SMART SM00091 282 350 6.0E-4 T 09-03-2017 IPR000014 PAS domain L21SP3_RS05405 a5a66324c499c4429baa3ad2cb16ab22 1508 Gene3D G3DSA:3.30.565.10 1091 1265 1.7E-39 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS02810 99e65d24ef4abc771c44da395768e73c 980 ProSitePatterns PS00018 EF-hand calcium-binding domain. 960 972 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS02810 99e65d24ef4abc771c44da395768e73c 980 SUPERFAMILY SSF48230 274 597 1.01E-43 T 09-03-2017 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 L21SP3_RS02810 99e65d24ef4abc771c44da395768e73c 980 Pfam PF05426 Alginate lyase 313 541 6.0E-14 T 09-03-2017 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 L21SP3_RS02810 99e65d24ef4abc771c44da395768e73c 980 Gene3D G3DSA:2.60.40.10 638 710 3.0E-14 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS02810 99e65d24ef4abc771c44da395768e73c 980 SUPERFAMILY SSF49265 636 707 1.95E-5 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 L21SP3_RS02810 99e65d24ef4abc771c44da395768e73c 980 Gene3D G3DSA:2.60.120.200 712 928 1.8E-31 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS02810 99e65d24ef4abc771c44da395768e73c 980 Gene3D G3DSA:1.50.10.110 307 607 5.9E-39 T 09-03-2017 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 L21SP3_RS02810 99e65d24ef4abc771c44da395768e73c 980 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 767 924 2.0E-29 T 09-03-2017 L21SP3_RS02810 99e65d24ef4abc771c44da395768e73c 980 SUPERFAMILY SSF49899 723 929 3.59E-33 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS11375 81ce00fa504e5c94034b41dead0ae28b 187 Pfam PF04542 Sigma-70 region 2 34 97 7.7E-10 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS11375 81ce00fa504e5c94034b41dead0ae28b 187 SUPERFAMILY SSF88946 13 111 2.28E-18 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS11375 81ce00fa504e5c94034b41dead0ae28b 187 Gene3D G3DSA:1.10.10.10 123 184 4.9E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS11375 81ce00fa504e5c94034b41dead0ae28b 187 Gene3D G3DSA:1.10.1740.10 13 122 1.1E-22 T 09-03-2017 L21SP3_RS11375 81ce00fa504e5c94034b41dead0ae28b 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 180 2.7E-29 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS11375 81ce00fa504e5c94034b41dead0ae28b 187 Pfam PF08281 Sigma-70, region 4 128 178 2.6E-14 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS11375 81ce00fa504e5c94034b41dead0ae28b 187 SUPERFAMILY SSF88659 117 183 6.35E-15 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS08260 ace41a98838fbf733cf33c3e494eff53 134 Pfam PF00872 Transposase, Mutator family 15 103 1.8E-22 T 09-03-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 L21SP3_RS11120 af4cbbbd98f332276f41b7583702bc51 343 SUPERFAMILY SSF102114 103 298 1.03E-16 T 09-03-2017 L21SP3_RS11120 af4cbbbd98f332276f41b7583702bc51 343 Pfam PF04055 Radical SAM superfamily 107 273 1.3E-17 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS11120 af4cbbbd98f332276f41b7583702bc51 343 SMART SM00729 102 313 0.0055 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP3_RS11120 af4cbbbd98f332276f41b7583702bc51 343 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 2 341 59.624 T 09-03-2017 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS11120 af4cbbbd98f332276f41b7583702bc51 343 PIRSF PIRSF006004 1 343 7.2E-113 T 09-03-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS11120 af4cbbbd98f332276f41b7583702bc51 343 Pfam PF13394 4Fe-4S single cluster domain 110 208 7.9E-5 T 09-03-2017 L21SP3_RS11120 af4cbbbd98f332276f41b7583702bc51 343 Gene3D G3DSA:3.20.20.70 103 329 3.0E-17 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS11120 af4cbbbd98f332276f41b7583702bc51 343 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 2 338 5.7E-103 T 09-03-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS10805 3af502704feae934293e8311daf4fdb6 157 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 09-03-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS10805 3af502704feae934293e8311daf4fdb6 157 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 5 157 9.1E-56 T 09-03-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 L21SP3_RS10805 3af502704feae934293e8311daf4fdb6 157 Pfam PF00177 Ribosomal protein S7p/S5e 1 150 1.3E-56 T 09-03-2017 IPR023798 Ribosomal protein S7 domain L21SP3_RS10805 3af502704feae934293e8311daf4fdb6 157 SUPERFAMILY SSF47973 6 153 5.49E-51 T 09-03-2017 IPR023798 Ribosomal protein S7 domain L21SP3_RS10805 3af502704feae934293e8311daf4fdb6 157 PIRSF PIRSF002122 2 157 1.3E-54 T 09-03-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 L21SP3_RS10805 3af502704feae934293e8311daf4fdb6 157 Gene3D G3DSA:1.10.455.10 9 157 6.3E-57 T 09-03-2017 IPR023798 Ribosomal protein S7 domain L21SP3_RS10805 3af502704feae934293e8311daf4fdb6 157 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 157 31.404 T 09-03-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 L21SP3_RS11155 1420715b58f9ef1e6b51d1a69b8e0487 517 SUPERFAMILY SSF109604 330 514 1.57E-39 T 09-03-2017 L21SP3_RS11155 1420715b58f9ef1e6b51d1a69b8e0487 517 Gene3D G3DSA:3.30.420.40 10 133 7.7E-33 T 09-03-2017 L21SP3_RS11155 1420715b58f9ef1e6b51d1a69b8e0487 517 Gene3D G3DSA:1.10.3210.10 339 466 9.2E-11 T 09-03-2017 IPR006674 HD domain L21SP3_RS11155 1420715b58f9ef1e6b51d1a69b8e0487 517 SUPERFAMILY SSF53067 12 133 1.37E-27 T 09-03-2017 L21SP3_RS11155 1420715b58f9ef1e6b51d1a69b8e0487 517 Pfam PF01966 HD domain 352 462 1.3E-8 T 09-03-2017 IPR006674 HD domain L21SP3_RS11155 1420715b58f9ef1e6b51d1a69b8e0487 517 SUPERFAMILY SSF53067 145 317 2.05E-20 T 09-03-2017 L21SP3_RS11155 1420715b58f9ef1e6b51d1a69b8e0487 517 Gene3D G3DSA:3.30.420.150 144 316 2.0E-18 T 09-03-2017 L21SP3_RS11155 1420715b58f9ef1e6b51d1a69b8e0487 517 PIRSF PIRSF001267 5 516 4.7E-79 T 09-03-2017 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 L21SP3_RS11155 1420715b58f9ef1e6b51d1a69b8e0487 517 Pfam PF02541 Ppx/GppA phosphatase family 26 316 1.2E-33 T 09-03-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 L21SP3_RS11155 1420715b58f9ef1e6b51d1a69b8e0487 517 SMART SM00471 339 472 3.4E-4 T 09-03-2017 IPR003607 HD/PDEase domain L21SP3_RS03035 7fb637976ce91bf93c228854aa55e61c 250 Gene3D G3DSA:3.40.10.10 175 247 7.6E-10 T 09-03-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 L21SP3_RS03035 7fb637976ce91bf93c228854aa55e61c 250 Pfam PF02805 Metal binding domain of Ada 188 236 5.4E-5 T 09-03-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 L21SP3_RS03035 7fb637976ce91bf93c228854aa55e61c 250 SUPERFAMILY SSF57884 182 237 2.22E-9 T 09-03-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 L21SP3_RS01200 192d918c740d31cb82fea9856e9a504c 808 Gene3D G3DSA:2.60.120.200 613 712 3.5E-4 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS01200 192d918c740d31cb82fea9856e9a504c 808 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 458 799 4.1E-45 T 09-03-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 L21SP3_RS01200 192d918c740d31cb82fea9856e9a504c 808 Pfam PF02018 Carbohydrate binding domain 60 205 1.2E-5 T 09-03-2017 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 L21SP3_RS01200 192d918c740d31cb82fea9856e9a504c 808 SUPERFAMILY SSF51011 715 806 3.06E-8 T 09-03-2017 L21SP3_RS01200 192d918c740d31cb82fea9856e9a504c 808 Gene3D G3DSA:2.60.120.260 61 218 9.7E-9 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01200 192d918c740d31cb82fea9856e9a504c 808 SMART SM00813 458 799 1.5E-43 T 09-03-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 L21SP3_RS01200 192d918c740d31cb82fea9856e9a504c 808 SUPERFAMILY SSF51445 197 534 1.81E-63 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS04715 09b0e5e946db75efad013d2b778aecc2 342 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 256 330 3.4E-30 T 09-03-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 L21SP3_RS04715 09b0e5e946db75efad013d2b778aecc2 342 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 342 143.692 T 09-03-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 L21SP3_RS04715 09b0e5e946db75efad013d2b778aecc2 342 SUPERFAMILY SSF46785 260 331 2.18E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS04715 09b0e5e946db75efad013d2b778aecc2 342 Gene3D G3DSA:3.40.50.300 23 182 3.0E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04715 09b0e5e946db75efad013d2b778aecc2 342 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 10 238 2.8E-101 T 09-03-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 L21SP3_RS04715 09b0e5e946db75efad013d2b778aecc2 342 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 253 331 8.0E-17 T 09-03-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 L21SP3_RS04715 09b0e5e946db75efad013d2b778aecc2 342 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 27 329 3.2E-130 T 09-03-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 L21SP3_RS04715 09b0e5e946db75efad013d2b778aecc2 342 Gene3D G3DSA:1.10.10.10 260 330 3.9E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS04715 09b0e5e946db75efad013d2b778aecc2 342 SMART SM00382 54 181 7.9E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS04715 09b0e5e946db75efad013d2b778aecc2 342 SUPERFAMILY SSF52540 23 253 2.28E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04715 09b0e5e946db75efad013d2b778aecc2 342 Gene3D G3DSA:1.10.8.60 186 258 1.6E-28 T 09-03-2017 L21SP3_RS08350 143cc924fc169ee267201d82cf23e9ed 143 SUPERFAMILY SSF46785 5 108 3.5E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS08350 143cc924fc169ee267201d82cf23e9ed 143 Pfam PF01475 Ferric uptake regulator family 12 121 1.1E-11 T 09-03-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 L21SP3_RS08350 143cc924fc169ee267201d82cf23e9ed 143 Gene3D G3DSA:1.10.10.10 5 79 1.5E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS02120 359b4006de67acbea7b1c903ff64de42 725 SMART SM00560 528 670 0.0063 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS02120 359b4006de67acbea7b1c903ff64de42 725 Pfam PF13927 Immunoglobulin domain 361 445 1.2E-9 T 09-03-2017 L21SP3_RS02120 359b4006de67acbea7b1c903ff64de42 725 Gene3D G3DSA:2.60.40.10 360 460 7.0E-13 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS02120 359b4006de67acbea7b1c903ff64de42 725 SUPERFAMILY SSF49899 462 677 2.16E-24 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS02120 359b4006de67acbea7b1c903ff64de42 725 Gene3D G3DSA:2.60.120.200 461 679 9.3E-21 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS02120 359b4006de67acbea7b1c903ff64de42 725 SMART SM00409 367 460 3.5E-6 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS02120 359b4006de67acbea7b1c903ff64de42 725 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 527 673 3.2E-16 T 09-03-2017 L21SP3_RS02120 359b4006de67acbea7b1c903ff64de42 725 SUPERFAMILY SSF48726 361 460 2.01E-13 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS01315 1c93943658e37f52e5279b84bf5bce45 445 SUPERFAMILY SSF53901 247 442 1.53E-30 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01315 1c93943658e37f52e5279b84bf5bce45 445 Gene3D G3DSA:3.40.47.10 305 442 1.5E-22 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01315 1c93943658e37f52e5279b84bf5bce45 445 SUPERFAMILY SSF53901 13 285 9.69E-42 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01315 1c93943658e37f52e5279b84bf5bce45 445 Gene3D G3DSA:3.40.47.10 12 289 3.9E-40 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01315 1c93943658e37f52e5279b84bf5bce45 445 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 287 398 5.2E-13 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal L21SP3_RS01315 1c93943658e37f52e5279b84bf5bce45 445 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 277 7.0E-27 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 28 39 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 PRINTS PR00987 Glutamyl-tRNA synthetase signature 227 235 2.2E-28 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 PRINTS PR00987 Glutamyl-tRNA synthetase signature 25 37 2.2E-28 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 PRINTS PR00987 Glutamyl-tRNA synthetase signature 39 50 2.2E-28 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 PRINTS PR00987 Glutamyl-tRNA synthetase signature 211 221 2.2E-28 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 PRINTS PR00987 Glutamyl-tRNA synthetase signature 54 67 2.2E-28 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 22 556 31.615 T 09-03-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 Gene3D G3DSA:3.90.800.10 87 212 2.0E-38 T 09-03-2017 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 Gene3D G3DSA:1.10.260.40 278 332 3.3E-5 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 23 313 1.3E-89 T 09-03-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 336 392 1.7E-7 T 09-03-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 SMART SM00530 278 333 3.7E-4 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 23 278 2.2E-105 T 09-03-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 SUPERFAMILY SSF48163 388 556 3.01E-30 T 09-03-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 Gene3D G3DSA:1.10.10.350 459 557 6.8E-26 T 09-03-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 SUPERFAMILY SSF52374 22 274 2.02E-103 T 09-03-2017 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 SUPERFAMILY SSF52374 331 386 2.02E-103 T 09-03-2017 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 Gene3D G3DSA:3.40.50.620 22 86 7.5E-53 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 Gene3D G3DSA:3.40.50.620 213 261 7.5E-53 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 Gene3D G3DSA:1.10.1160.10 266 277 7.4E-23 T 09-03-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 L21SP3_RS08880 983c235a8334585700f9d1180568c4f2 564 Gene3D G3DSA:1.10.1160.10 335 403 7.4E-23 T 09-03-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 L21SP3_RS00575 a5a8889266b9a6316ddc88b1af8c16a0 138 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 12 138 9.4E-34 T 09-03-2017 IPR001602 Uncharacterised protein family UPF0047 L21SP3_RS00575 a5a8889266b9a6316ddc88b1af8c16a0 138 SUPERFAMILY SSF111038 1 138 9.68E-45 T 09-03-2017 IPR001602 Uncharacterised protein family UPF0047 L21SP3_RS00575 a5a8889266b9a6316ddc88b1af8c16a0 138 Gene3D G3DSA:2.60.120.460 1 138 1.4E-47 T 09-03-2017 IPR001602 Uncharacterised protein family UPF0047 L21SP3_RS00575 a5a8889266b9a6316ddc88b1af8c16a0 138 PIRSF PIRSF004681 1 138 4.5E-40 T 09-03-2017 IPR001602 Uncharacterised protein family UPF0047 L21SP3_RS00575 a5a8889266b9a6316ddc88b1af8c16a0 138 Pfam PF01894 Uncharacterised protein family UPF0047 20 135 1.5E-34 T 09-03-2017 IPR001602 Uncharacterised protein family UPF0047 L21SP3_RS09305 5f1288f482149ca162b86481a09eb21d 760 Pfam PF13927 Immunoglobulin domain 395 474 1.5E-10 T 09-03-2017 L21SP3_RS09305 5f1288f482149ca162b86481a09eb21d 760 SUPERFAMILY SSF48726 395 484 2.6E-13 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS09305 5f1288f482149ca162b86481a09eb21d 760 SMART SM00409 401 489 2.6E-8 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS09305 5f1288f482149ca162b86481a09eb21d 760 Gene3D G3DSA:2.60.120.200 528 713 6.7E-26 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS09305 5f1288f482149ca162b86481a09eb21d 760 Gene3D G3DSA:2.60.40.10 394 486 1.1E-14 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS09305 5f1288f482149ca162b86481a09eb21d 760 SUPERFAMILY SSF49899 484 712 2.72E-24 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS09305 5f1288f482149ca162b86481a09eb21d 760 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 555 707 1.2E-19 T 09-03-2017 L21SP3_RS09695 76d1f0c2ce7dc6f1c35ded124b607a0f 367 Pfam PF04616 Glycosyl hydrolases family 43 72 278 2.1E-14 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS09695 76d1f0c2ce7dc6f1c35ded124b607a0f 367 Gene3D G3DSA:2.115.10.20 41 310 1.2E-38 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS09695 76d1f0c2ce7dc6f1c35ded124b607a0f 367 SUPERFAMILY SSF75005 39 308 9.42E-36 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS08915 a847aadc6bdb5bed6c4ee83b738d05e2 508 Pfam PF00005 ABC transporter 277 431 8.3E-20 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS08915 a847aadc6bdb5bed6c4ee83b738d05e2 508 Pfam PF00005 ABC transporter 20 170 2.1E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS08915 a847aadc6bdb5bed6c4ee83b738d05e2 508 SMART SM00382 285 480 9.6E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS08915 a847aadc6bdb5bed6c4ee83b738d05e2 508 SMART SM00382 29 218 2.4E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS08915 a847aadc6bdb5bed6c4ee83b738d05e2 508 Gene3D G3DSA:3.40.50.300 2 236 5.8E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08915 a847aadc6bdb5bed6c4ee83b738d05e2 508 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS08915 a847aadc6bdb5bed6c4ee83b738d05e2 508 SUPERFAMILY SSF52540 4 231 1.2E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08915 a847aadc6bdb5bed6c4ee83b738d05e2 508 Gene3D G3DSA:3.40.50.300 249 501 1.6E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08915 a847aadc6bdb5bed6c4ee83b738d05e2 508 SUPERFAMILY SSF52540 271 494 3.65E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00965 306657849d45725f587c246e5d9c0564 290 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 114 288 2.4E-49 T 09-03-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 L21SP3_RS00965 306657849d45725f587c246e5d9c0564 290 Gene3D G3DSA:3.20.20.70 135 278 9.2E-48 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS00965 306657849d45725f587c246e5d9c0564 290 SUPERFAMILY SSF54675 12 113 3.57E-27 T 09-03-2017 L21SP3_RS00965 306657849d45725f587c246e5d9c0564 290 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 24 112 1.4E-22 T 09-03-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 L21SP3_RS00965 306657849d45725f587c246e5d9c0564 290 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 15 288 9.4E-80 T 09-03-2017 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 L21SP3_RS00965 306657849d45725f587c246e5d9c0564 290 PIRSF PIRSF006250 7 289 4.2E-75 T 09-03-2017 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 L21SP3_RS00965 306657849d45725f587c246e5d9c0564 290 SUPERFAMILY SSF51690 114 288 2.35E-50 T 09-03-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 L21SP3_RS00965 306657849d45725f587c246e5d9c0564 290 Gene3D G3DSA:3.90.1170.20 10 134 9.3E-42 T 09-03-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 L21SP3_RS09480 2794814271e94f05406da7ba4573c0ae 263 PIRSF PIRSF000161 1 263 3.3E-79 T 09-03-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS09480 2794814271e94f05406da7ba4573c0ae 263 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 147 164 - T 09-03-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS09480 2794814271e94f05406da7ba4573c0ae 263 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 122 1.9E-30 T 09-03-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS09480 2794814271e94f05406da7ba4573c0ae 263 SUPERFAMILY SSF51735 1 123 1.13E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS09480 2794814271e94f05406da7ba4573c0ae 263 SUPERFAMILY SSF51735 233 263 1.13E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS09480 2794814271e94f05406da7ba4573c0ae 263 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 2 262 2.8E-81 T 09-03-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS09480 2794814271e94f05406da7ba4573c0ae 263 Gene3D G3DSA:3.40.50.720 1 160 2.6E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS09480 2794814271e94f05406da7ba4573c0ae 263 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 262 31.137 T 09-03-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS09480 2794814271e94f05406da7ba4573c0ae 263 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 125 261 2.2E-40 T 09-03-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS09480 2794814271e94f05406da7ba4573c0ae 263 SUPERFAMILY SSF55347 124 233 4.8E-30 T 09-03-2017 L21SP3_RS00885 ee7ef8076658e8ccf10274eef1d7a508 279 Gene3D G3DSA:3.30.700.10 6 39 3.4E-5 T 09-03-2017 L21SP3_RS00885 ee7ef8076658e8ccf10274eef1d7a508 279 SUPERFAMILY SSF54523 6 87 2.04E-13 T 09-03-2017 L21SP3_RS00885 ee7ef8076658e8ccf10274eef1d7a508 279 Pfam PF13633 Prokaryotic N-terminal methylation site 4 29 1.6E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS00885 ee7ef8076658e8ccf10274eef1d7a508 279 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 25 1.4E-6 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS00885 ee7ef8076658e8ccf10274eef1d7a508 279 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 224 238 0.0017 T 09-03-2017 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP3_RS06750 8aea88a1a118f8f219dce6a5adc27593 252 SUPERFAMILY SSF46785 7 67 2.11E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS06750 8aea88a1a118f8f219dce6a5adc27593 252 Gene3D G3DSA:1.10.10.10 7 78 3.3E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS06750 8aea88a1a118f8f219dce6a5adc27593 252 SUPERFAMILY SSF47979 68 143 6.41E-17 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP3_RS06750 8aea88a1a118f8f219dce6a5adc27593 252 SMART SM00529 29 128 9.5E-29 T 09-03-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 L21SP3_RS06750 8aea88a1a118f8f219dce6a5adc27593 252 SMART SM00899 180 251 1.4E-19 T 09-03-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 L21SP3_RS06750 8aea88a1a118f8f219dce6a5adc27593 252 Gene3D G3DSA:1.10.60.10 79 142 4.4E-16 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP3_RS06750 8aea88a1a118f8f219dce6a5adc27593 252 Pfam PF04023 FeoA domain 181 250 7.3E-17 T 09-03-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 L21SP3_RS06750 8aea88a1a118f8f219dce6a5adc27593 252 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 6 63 1.1E-13 T 09-03-2017 IPR022687 DTXR-type HTH domain GO:0003677 L21SP3_RS06750 8aea88a1a118f8f219dce6a5adc27593 252 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 68 132 1.9E-20 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP3_RS06750 8aea88a1a118f8f219dce6a5adc27593 252 SUPERFAMILY SSF50037 182 251 5.04E-16 T 09-03-2017 IPR008988 Transcriptional repressor, C-terminal L21SP3_RS07750 bd302f0f530d0ea3248037acb3ba94c4 367 SUPERFAMILY SSF55979 1 117 8.64E-17 T 09-03-2017 L21SP3_RS07750 bd302f0f530d0ea3248037acb3ba94c4 367 PIRSF PIRSF000804 1 367 3.2E-96 T 09-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS07750 bd302f0f530d0ea3248037acb3ba94c4 367 Gene3D G3DSA:3.10.150.10 252 366 9.0E-30 T 09-03-2017 L21SP3_RS07750 bd302f0f530d0ea3248037acb3ba94c4 367 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 249 365 5.0E-23 T 09-03-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS07750 bd302f0f530d0ea3248037acb3ba94c4 367 Gene3D G3DSA:3.10.150.10 127 251 7.3E-27 T 09-03-2017 L21SP3_RS07750 bd302f0f530d0ea3248037acb3ba94c4 367 Gene3D G3DSA:3.10.150.10 1 117 1.7E-19 T 09-03-2017 L21SP3_RS07750 bd302f0f530d0ea3248037acb3ba94c4 367 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 245 5.7E-23 T 09-03-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS07750 bd302f0f530d0ea3248037acb3ba94c4 367 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 366 5.0E-79 T 09-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS07750 bd302f0f530d0ea3248037acb3ba94c4 367 SUPERFAMILY SSF55979 249 366 5.5E-27 T 09-03-2017 L21SP3_RS07750 bd302f0f530d0ea3248037acb3ba94c4 367 SMART SM00480 17 363 1.5E-82 T 09-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS07750 bd302f0f530d0ea3248037acb3ba94c4 367 SUPERFAMILY SSF55979 127 247 3.84E-19 T 09-03-2017 L21SP3_RS07750 bd302f0f530d0ea3248037acb3ba94c4 367 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 117 8.7E-22 T 09-03-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS07470 d5e9ccebe0714f0d1d83ffee5591f3fc 367 Gene3D G3DSA:3.20.20.210 92 357 3.5E-8 T 09-03-2017 L21SP3_RS07470 d5e9ccebe0714f0d1d83ffee5591f3fc 367 SUPERFAMILY SSF51726 83 359 6.02E-9 T 09-03-2017 L21SP3_RS02705 849301354191bd651bef45a2b3f165f0 405 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 5 398 51.471 T 09-03-2017 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 L21SP3_RS02705 849301354191bd651bef45a2b3f165f0 405 SUPERFAMILY SSF142695 208 379 1.12E-65 T 09-03-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 L21SP3_RS02705 849301354191bd651bef45a2b3f165f0 405 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 4 206 38.318 T 09-03-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS02705 849301354191bd651bef45a2b3f165f0 405 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 10 201 4.8E-82 T 09-03-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS02705 849301354191bd651bef45a2b3f165f0 405 Pfam PF00925 GTP cyclohydrolase II 211 376 2.6E-69 T 09-03-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 L21SP3_RS02705 849301354191bd651bef45a2b3f165f0 405 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 207 402 40.101 T 09-03-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 L21SP3_RS02705 849301354191bd651bef45a2b3f165f0 405 Gene3D G3DSA:3.90.870.10 2 212 8.3E-95 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain L21SP3_RS02705 849301354191bd651bef45a2b3f165f0 405 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 7 202 2.3E-74 T 09-03-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS02705 849301354191bd651bef45a2b3f165f0 405 PIRSF PIRSF001259 4 405 2.4E-172 T 09-03-2017 L21SP3_RS02705 849301354191bd651bef45a2b3f165f0 405 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 212 400 2.0E-77 T 09-03-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 L21SP3_RS02705 849301354191bd651bef45a2b3f165f0 405 SUPERFAMILY SSF55821 4 205 8.47E-83 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain L21SP3_RS01470 afd170db36710bdacecf8a64b7ee601c 147 Pfam PF07233 Protein of unknown function (DUF1425) 58 142 1.8E-19 T 09-03-2017 IPR010824 Protein of unknown function DUF1425 L21SP3_RS10410 a29d03f21667aa2eb6bbc608e5278f55 143 PRINTS PR01853 Bacterial YajC preprotein translocase signature 94 112 7.9E-7 T 09-03-2017 IPR003849 Preprotein translocase YajC L21SP3_RS10410 a29d03f21667aa2eb6bbc608e5278f55 143 PRINTS PR01853 Bacterial YajC preprotein translocase signature 56 76 7.9E-7 T 09-03-2017 IPR003849 Preprotein translocase YajC L21SP3_RS10410 a29d03f21667aa2eb6bbc608e5278f55 143 SMART SM01323 54 138 5.3E-28 T 09-03-2017 IPR003849 Preprotein translocase YajC L21SP3_RS10410 a29d03f21667aa2eb6bbc608e5278f55 143 Pfam PF02699 Preprotein translocase subunit 58 135 3.5E-23 T 09-03-2017 IPR003849 Preprotein translocase YajC L21SP3_RS10410 a29d03f21667aa2eb6bbc608e5278f55 143 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 58 128 2.5E-18 T 09-03-2017 IPR003849 Preprotein translocase YajC L21SP3_RS03070 353f25a9647af4c9141b53bfdd39ce4d 312 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 20 281 4.2E-17 T 09-03-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 L21SP3_RS03070 353f25a9647af4c9141b53bfdd39ce4d 312 SUPERFAMILY SSF51366 4 295 2.73E-56 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP3_RS03070 353f25a9647af4c9141b53bfdd39ce4d 312 Gene3D G3DSA:3.20.20.70 9 294 2.9E-48 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS03070 353f25a9647af4c9141b53bfdd39ce4d 312 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 103 116 - T 09-03-2017 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 L21SP3_RS03070 353f25a9647af4c9141b53bfdd39ce4d 312 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 5 280 6.6E-66 T 09-03-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 L21SP3_RS03070 353f25a9647af4c9141b53bfdd39ce4d 312 SMART SM00934 19 287 3.9E-9 T 09-03-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 L21SP3_RS08230 71c932bde6c86cf8a45a4bad60ad4709 323 Gene3D G3DSA:3.20.20.70 9 250 3.0E-61 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS08230 71c932bde6c86cf8a45a4bad60ad4709 323 SUPERFAMILY SSF51395 12 321 1.05E-64 T 09-03-2017 L21SP3_RS08230 71c932bde6c86cf8a45a4bad60ad4709 323 Pfam PF01207 Dihydrouridine synthase (Dus) 16 308 6.3E-60 T 09-03-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 L21SP3_RS08230 71c932bde6c86cf8a45a4bad60ad4709 323 Gene3D G3DSA:1.10.1200.80 255 321 1.6E-6 T 09-03-2017 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 L21SP3_RS08230 71c932bde6c86cf8a45a4bad60ad4709 323 PIRSF PIRSF006621 1 322 1.6E-70 T 09-03-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 L21SP3_RS05915 b6ab51783197b49668b62bf55df15d27 291 Pfam PF01040 UbiA prenyltransferase family 43 224 2.5E-27 T 09-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 L21SP3_RS05885 40388dabba7e5b7e2e3a1c8f4b0dc012 431 Gene3D G3DSA:3.65.10.10 235 422 1.7E-56 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 L21SP3_RS05885 40388dabba7e5b7e2e3a1c8f4b0dc012 431 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 09-03-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 L21SP3_RS05885 40388dabba7e5b7e2e3a1c8f4b0dc012 431 SUPERFAMILY SSF55205 2 423 2.06E-108 T 09-03-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 L21SP3_RS05885 40388dabba7e5b7e2e3a1c8f4b0dc012 431 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 422 7.4E-117 T 09-03-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 L21SP3_RS05885 40388dabba7e5b7e2e3a1c8f4b0dc012 431 Gene3D G3DSA:3.65.10.10 20 234 1.5E-42 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 L21SP3_RS05885 40388dabba7e5b7e2e3a1c8f4b0dc012 431 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 416 4.1E-98 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 L21SP3_RS05885 40388dabba7e5b7e2e3a1c8f4b0dc012 431 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 424 30.876 T 09-03-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 L21SP3_RS05885 40388dabba7e5b7e2e3a1c8f4b0dc012 431 PIRSF PIRSF000505 1 427 1.4E-125 T 09-03-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 L21SP3_RS07085 a2015198f56422f7c53f265ecd678936 170 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 1 170 19.373 T 09-03-2017 IPR022929 Putative manganese efflux pump MntP L21SP3_RS07085 a2015198f56422f7c53f265ecd678936 170 Pfam PF02659 Putative manganese efflux pump 18 167 1.1E-40 T 09-03-2017 IPR003810 Putative manganese efflux pump L21SP3_RS11640 050d2a889bb2c6f861d97b8f89876d60 381 SMART SM00382 177 315 0.0034 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS11640 050d2a889bb2c6f861d97b8f89876d60 381 Gene3D G3DSA:3.30.1360.120 2 101 2.9E-6 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 L21SP3_RS11640 050d2a889bb2c6f861d97b8f89876d60 381 Pfam PF01926 50S ribosome-binding GTPase 180 277 4.3E-19 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS11640 050d2a889bb2c6f861d97b8f89876d60 381 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 181 201 6.9E-6 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS11640 050d2a889bb2c6f861d97b8f89876d60 381 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 249 267 6.9E-6 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS11640 050d2a889bb2c6f861d97b8f89876d60 381 SUPERFAMILY SSF52540 180 329 9.66E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11640 050d2a889bb2c6f861d97b8f89876d60 381 SUPERFAMILY SSF103025 2 104 6.28E-7 T 09-03-2017 L21SP3_RS11640 050d2a889bb2c6f861d97b8f89876d60 381 Pfam PF10396 GTP-binding protein TrmE N-terminus 2 104 5.9E-5 T 09-03-2017 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 L21SP3_RS11640 050d2a889bb2c6f861d97b8f89876d60 381 Gene3D G3DSA:3.40.50.300 178 329 3.9E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11640 050d2a889bb2c6f861d97b8f89876d60 381 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 180 305 7.5E-17 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP3_RS09445 e34013c58bca7119fac1d9c3e48f1e4a 397 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 6 395 2.6E-119 T 09-03-2017 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS09445 e34013c58bca7119fac1d9c3e48f1e4a 397 PIRSF PIRSF006392 1 397 9.8E-128 T 09-03-2017 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS09445 e34013c58bca7119fac1d9c3e48f1e4a 397 SUPERFAMILY SSF53649 6 72 1.01E-26 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09445 e34013c58bca7119fac1d9c3e48f1e4a 397 SUPERFAMILY SSF53649 183 361 1.01E-26 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09445 e34013c58bca7119fac1d9c3e48f1e4a 397 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 40 201 2.0E-54 T 09-03-2017 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS09445 e34013c58bca7119fac1d9c3e48f1e4a 397 Pfam PF01676 Metalloenzyme superfamily 4 369 1.2E-35 T 09-03-2017 IPR006124 Metalloenzyme GO:0003824|GO:0046872 L21SP3_RS09445 e34013c58bca7119fac1d9c3e48f1e4a 397 TIGRFAM TIGR02535 hyp_Hser_kinase: proposed homoserine kinase 4 396 2.8E-154 T 09-03-2017 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS09445 e34013c58bca7119fac1d9c3e48f1e4a 397 Gene3D G3DSA:3.40.720.10 10 82 5.9E-26 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS09445 e34013c58bca7119fac1d9c3e48f1e4a 397 Gene3D G3DSA:3.40.720.10 189 361 5.9E-26 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS04100 055fcf2ece738b912e4b425de0c4584b 520 Gene3D G3DSA:3.40.1450.10 81 311 5.1E-97 T 09-03-2017 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS04100 055fcf2ece738b912e4b425de0c4584b 520 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 5 515 3.4E-204 T 09-03-2017 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS04100 055fcf2ece738b912e4b425de0c4584b 520 Gene3D G3DSA:3.40.720.10 317 516 1.8E-82 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS04100 055fcf2ece738b912e4b425de0c4584b 520 Gene3D G3DSA:3.40.720.10 4 80 1.8E-82 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS04100 055fcf2ece738b912e4b425de0c4584b 520 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 516 47.761 T 09-03-2017 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS04100 055fcf2ece738b912e4b425de0c4584b 520 SUPERFAMILY SSF64158 80 311 2.62E-86 T 09-03-2017 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS04100 055fcf2ece738b912e4b425de0c4584b 520 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 85 301 1.2E-83 T 09-03-2017 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS04100 055fcf2ece738b912e4b425de0c4584b 520 Pfam PF01676 Metalloenzyme superfamily 5 505 2.0E-76 T 09-03-2017 IPR006124 Metalloenzyme GO:0003824|GO:0046872 L21SP3_RS04100 055fcf2ece738b912e4b425de0c4584b 520 PIRSF PIRSF001492 1 518 4.0E-202 T 09-03-2017 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS04100 055fcf2ece738b912e4b425de0c4584b 520 SUPERFAMILY SSF53649 4 80 1.83E-67 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS04100 055fcf2ece738b912e4b425de0c4584b 520 SUPERFAMILY SSF53649 313 515 1.83E-67 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS11045 907ba28b20858c7e1c8a8224313697e3 222 Gene3D G3DSA:1.20.58.220 116 221 2.7E-27 T 09-03-2017 L21SP3_RS11045 907ba28b20858c7e1c8a8224313697e3 222 PIRSF PIRSF003107 1 217 4.2E-62 T 09-03-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 L21SP3_RS11045 907ba28b20858c7e1c8a8224313697e3 222 Pfam PF01895 PhoU domain 17 104 4.2E-21 T 09-03-2017 IPR026022 PhoU domain L21SP3_RS11045 907ba28b20858c7e1c8a8224313697e3 222 Pfam PF01895 PhoU domain 121 203 7.5E-19 T 09-03-2017 IPR026022 PhoU domain L21SP3_RS11045 907ba28b20858c7e1c8a8224313697e3 222 SUPERFAMILY SSF109755 5 219 2.3E-61 T 09-03-2017 L21SP3_RS11045 907ba28b20858c7e1c8a8224313697e3 222 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 213 1.3E-59 T 09-03-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 L21SP3_RS11045 907ba28b20858c7e1c8a8224313697e3 222 Gene3D G3DSA:1.20.58.220 4 108 3.0E-32 T 09-03-2017 L21SP3_RS00200 b7c7238c73d864ff5784baf4d950420b 190 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 183 3.9E-42 T 09-03-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 L21SP3_RS00200 b7c7238c73d864ff5784baf4d950420b 190 Gene3D G3DSA:3.90.1140.10 1 184 7.6E-45 T 09-03-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase L21SP3_RS00200 b7c7238c73d864ff5784baf4d950420b 190 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 186 21.754 T 09-03-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 L21SP3_RS00200 b7c7238c73d864ff5784baf4d950420b 190 SUPERFAMILY SSF55144 1 186 2.44E-37 T 09-03-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase L21SP3_RS00200 b7c7238c73d864ff5784baf4d950420b 190 Pfam PF13563 2'-5' RNA ligase superfamily 22 168 7.9E-15 T 09-03-2017 L21SP3_RS10725 d9a2daa7307339db3ab66f33c59de37b 391 Gene3D G3DSA:1.20.1250.20 203 380 8.0E-11 T 09-03-2017 L21SP3_RS10725 d9a2daa7307339db3ab66f33c59de37b 391 Gene3D G3DSA:1.20.1250.20 8 187 3.1E-19 T 09-03-2017 L21SP3_RS10725 d9a2daa7307339db3ab66f33c59de37b 391 SUPERFAMILY SSF103473 8 374 1.16E-39 T 09-03-2017 IPR020846 Major facilitator superfamily domain L21SP3_RS10725 d9a2daa7307339db3ab66f33c59de37b 391 Pfam PF07690 Major Facilitator Superfamily 11 259 2.6E-22 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 L21SP3_RS03315 d9a2daa7307339db3ab66f33c59de37b 391 Gene3D G3DSA:1.20.1250.20 203 380 8.0E-11 T 09-03-2017 L21SP3_RS03315 d9a2daa7307339db3ab66f33c59de37b 391 Gene3D G3DSA:1.20.1250.20 8 187 3.1E-19 T 09-03-2017 L21SP3_RS03315 d9a2daa7307339db3ab66f33c59de37b 391 SUPERFAMILY SSF103473 8 374 1.16E-39 T 09-03-2017 IPR020846 Major facilitator superfamily domain L21SP3_RS03315 d9a2daa7307339db3ab66f33c59de37b 391 Pfam PF07690 Major Facilitator Superfamily 11 259 2.6E-22 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 L21SP3_RS03585 02ec170f08636f8548e3e26dfc555ac9 424 SUPERFAMILY SSF55347 177 314 6.1E-24 T 09-03-2017 L21SP3_RS03585 02ec170f08636f8548e3e26dfc555ac9 424 Gene3D G3DSA:3.30.360.10 183 319 1.4E-32 T 09-03-2017 L21SP3_RS03585 02ec170f08636f8548e3e26dfc555ac9 424 Gene3D G3DSA:3.30.360.10 366 420 1.4E-32 T 09-03-2017 L21SP3_RS03585 02ec170f08636f8548e3e26dfc555ac9 424 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 49 169 4.0E-21 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP3_RS03585 02ec170f08636f8548e3e26dfc555ac9 424 SUPERFAMILY SSF51735 39 202 6.97E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS03585 02ec170f08636f8548e3e26dfc555ac9 424 Gene3D G3DSA:3.40.50.720 44 182 5.4E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS03585 02ec170f08636f8548e3e26dfc555ac9 424 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 185 274 1.1E-7 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 L21SP3_RS03135 776c18912803a9c42ac3272034baf825 515 Pfam PF00128 Alpha amylase, catalytic domain 46 361 6.5E-84 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP3_RS03135 776c18912803a9c42ac3272034baf825 515 SUPERFAMILY SSF51011 428 465 4.46E-6 T 09-03-2017 L21SP3_RS03135 776c18912803a9c42ac3272034baf825 515 Gene3D G3DSA:3.90.400.10 129 183 2.9E-12 T 09-03-2017 L21SP3_RS03135 776c18912803a9c42ac3272034baf825 515 Gene3D G3DSA:2.60.40.1180 428 466 2.1E-5 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta L21SP3_RS03135 776c18912803a9c42ac3272034baf825 515 SUPERFAMILY SSF51445 22 425 5.15E-122 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS03135 776c18912803a9c42ac3272034baf825 515 Pfam PF16657 Maltogenic Amylase, C-terminal domain 428 466 2.2E-6 T 09-03-2017 IPR032091 Maltogenic Amylase, C-terminal L21SP3_RS03135 776c18912803a9c42ac3272034baf825 515 SMART SM00642 31 419 2.3E-106 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP3_RS03135 776c18912803a9c42ac3272034baf825 515 Gene3D G3DSA:3.20.20.80 187 426 4.6E-107 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS03135 776c18912803a9c42ac3272034baf825 515 Gene3D G3DSA:3.20.20.80 21 128 4.6E-107 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS11145 f2a9641d487f67a6044fe21ddc9425c1 467 Pfam PF00919 Uncharacterized protein family UPF0004 5 103 3.0E-28 T 09-03-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 L21SP3_RS11145 f2a9641d487f67a6044fe21ddc9425c1 467 Gene3D G3DSA:3.80.30.20 160 393 7.0E-75 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe L21SP3_RS11145 f2a9641d487f67a6044fe21ddc9425c1 467 SUPERFAMILY SSF102114 156 386 5.23E-57 T 09-03-2017 L21SP3_RS11145 f2a9641d487f67a6044fe21ddc9425c1 467 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 5 462 7.3E-128 T 09-03-2017 L21SP3_RS11145 f2a9641d487f67a6044fe21ddc9425c1 467 Pfam PF04055 Radical SAM superfamily 165 337 3.3E-32 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS11145 f2a9641d487f67a6044fe21ddc9425c1 467 Pfam PF01938 TRAM domain 422 463 6.9E-6 T 09-03-2017 IPR002792 TRAM domain L21SP3_RS11145 f2a9641d487f67a6044fe21ddc9425c1 467 SMART SM00729 160 382 2.1E-54 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP3_RS11145 f2a9641d487f67a6044fe21ddc9425c1 467 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 5 459 3.8E-125 T 09-03-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 L21SP3_RS11145 f2a9641d487f67a6044fe21ddc9425c1 467 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 164 184 - T 09-03-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 L21SP3_RS03685 1570b5375fff99fd976bff6799e4f1ba 446 Pfam PF04932 O-Antigen ligase 218 356 4.4E-7 T 09-03-2017 IPR007016 O-antigen ligase-related L21SP3_RS01525 3cdbeb815af95ac25ec46fa054e0d11a 191 Pfam PF01381 Helix-turn-helix 11 63 8.9E-10 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP3_RS01525 3cdbeb815af95ac25ec46fa054e0d11a 191 Pfam PF07883 Cupin domain 133 186 6.6E-11 T 09-03-2017 IPR013096 Cupin 2, conserved barrel L21SP3_RS01525 3cdbeb815af95ac25ec46fa054e0d11a 191 SUPERFAMILY SSF51182 76 187 7.38E-21 T 09-03-2017 IPR011051 RmlC-like cupin domain L21SP3_RS01525 3cdbeb815af95ac25ec46fa054e0d11a 191 Gene3D G3DSA:2.60.120.10 59 190 7.4E-25 T 09-03-2017 IPR014710 RmlC-like jelly roll fold L21SP3_RS01525 3cdbeb815af95ac25ec46fa054e0d11a 191 Gene3D G3DSA:1.10.260.40 3 58 3.7E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS01525 3cdbeb815af95ac25ec46fa054e0d11a 191 SUPERFAMILY SSF47413 3 70 4.79E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS01525 3cdbeb815af95ac25ec46fa054e0d11a 191 SMART SM00530 10 65 4.4E-10 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP3_RS02915 f3bbae023abd7eb89afc3b52165f28bf 779 Gene3D G3DSA:2.60.120.260 563 702 2.1E-19 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS02915 f3bbae023abd7eb89afc3b52165f28bf 779 Gene3D G3DSA:1.50.10.10 240 325 2.3E-6 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS02915 f3bbae023abd7eb89afc3b52165f28bf 779 Gene3D G3DSA:1.50.10.10 25 232 2.9E-20 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS02915 f3bbae023abd7eb89afc3b52165f28bf 779 Pfam PF03663 Glycosyl hydrolase family 76 59 288 6.6E-27 T 09-03-2017 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 L21SP3_RS02915 f3bbae023abd7eb89afc3b52165f28bf 779 SUPERFAMILY SSF49695 376 458 4.3E-11 T 09-03-2017 IPR011024 Gamma-crystallin-related L21SP3_RS02915 f3bbae023abd7eb89afc3b52165f28bf 779 SUPERFAMILY SSF48208 40 280 8.75E-29 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS02915 f3bbae023abd7eb89afc3b52165f28bf 779 SUPERFAMILY SSF48208 261 365 1.02E-5 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS02915 f3bbae023abd7eb89afc3b52165f28bf 779 SUPERFAMILY SSF49785 562 701 8.51E-19 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS02915 f3bbae023abd7eb89afc3b52165f28bf 779 Pfam PF00754 F5/8 type C domain 571 691 7.3E-14 T 09-03-2017 IPR000421 Coagulation factor 5/8 C-terminal domain L21SP3_RS02915 f3bbae023abd7eb89afc3b52165f28bf 779 Gene3D G3DSA:2.60.20.10 376 459 7.5E-19 T 09-03-2017 L21SP3_RS05810 f32f2b0a8274504d2bf0eb38d9166507 524 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 17 524 4.4E-197 T 09-03-2017 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 L21SP3_RS05810 f32f2b0a8274504d2bf0eb38d9166507 524 SUPERFAMILY SSF54791 212 297 2.13E-15 T 09-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 L21SP3_RS05810 f32f2b0a8274504d2bf0eb38d9166507 524 TIGRFAM TIGR00277 HDIG: HDIG domain 336 413 1.5E-21 T 09-03-2017 IPR006675 HDIG domain L21SP3_RS05810 f32f2b0a8274504d2bf0eb38d9166507 524 Gene3D G3DSA:3.30.1370.10 225 306 4.2E-7 T 09-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 L21SP3_RS05810 f32f2b0a8274504d2bf0eb38d9166507 524 SUPERFAMILY SSF109604 314 474 1.62E-27 T 09-03-2017 L21SP3_RS05810 f32f2b0a8274504d2bf0eb38d9166507 524 Hamap MF_00335 Ribonuclease Y [rny]. 2 524 22.889 T 09-03-2017 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 L21SP3_RS05810 f32f2b0a8274504d2bf0eb38d9166507 524 SMART SM00471 336 442 3.6E-8 T 09-03-2017 IPR003607 HD/PDEase domain L21SP3_RS05810 f32f2b0a8274504d2bf0eb38d9166507 524 Pfam PF00013 KH domain 218 270 3.8E-8 T 09-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 L21SP3_RS05810 f32f2b0a8274504d2bf0eb38d9166507 524 SMART SM00322 212 279 3.5E-8 T 09-03-2017 IPR004087 K Homology domain GO:0003676 L21SP3_RS05810 f32f2b0a8274504d2bf0eb38d9166507 524 Pfam PF12072 Domain of unknown function (DUF3552) 17 209 3.6E-37 T 09-03-2017 IPR022711 Ribonuclease Y, N-terminal L21SP3_RS05810 f32f2b0a8274504d2bf0eb38d9166507 524 Pfam PF01966 HD domain 341 432 1.6E-16 T 09-03-2017 IPR006674 HD domain L21SP3_RS05810 f32f2b0a8274504d2bf0eb38d9166507 524 Gene3D G3DSA:1.10.3210.10 330 500 3.4E-36 T 09-03-2017 IPR006674 HD domain L21SP3_RS06480 5beefb75f02dec4b31a493b588e72d23 218 SUPERFAMILY SSF52266 24 207 1.68E-25 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS06480 5beefb75f02dec4b31a493b588e72d23 218 Gene3D G3DSA:3.40.50.1110 24 210 1.0E-22 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS06480 5beefb75f02dec4b31a493b588e72d23 218 Pfam PF00657 GDSL-like Lipase/Acylhydrolase 25 205 1.8E-10 T 09-03-2017 IPR001087 GDSL lipase/esterase GO:0016788 L21SP3_RS01590 201f36c7d03b561e6c01ed7e4966dd73 470 SUPERFAMILY SSF53649 41 464 3.78E-122 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS01590 201f36c7d03b561e6c01ed7e4966dd73 470 Gene3D G3DSA:3.30.1120.10 410 465 9.3E-17 T 09-03-2017 L21SP3_RS01590 201f36c7d03b561e6c01ed7e4966dd73 470 Pfam PF00884 Sulfatase 43 372 6.8E-65 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS01590 201f36c7d03b561e6c01ed7e4966dd73 470 Gene3D G3DSA:3.40.720.10 41 409 2.7E-105 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 SUPERFAMILY SSF142984 374 457 1.05E-22 T 09-03-2017 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 SMART SM00928 462 507 6.8E-25 T 09-03-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 SUPERFAMILY SSF140490 458 559 2.09E-39 T 09-03-2017 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 Gene3D G3DSA:3.50.50.60 754 889 3.2E-45 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 Gene3D G3DSA:3.40.30.10 29 123 5.4E-26 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 SUPERFAMILY SSF46548 1005 1054 4.13E-5 T 09-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 SUPERFAMILY SSF52833 29 118 1.9E-20 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 560 640 6.0E-18 T 09-03-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 22 102 1.4E-6 T 09-03-2017 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 657 904 5.5E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 SUPERFAMILY SSF51971 656 897 1.18E-61 T 09-03-2017 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 463 547 1.3E-34 T 09-03-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 Pfam PF10531 SLBB domain 376 424 2.4E-7 T 09-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 SUPERFAMILY SSF142019 133 373 1.44E-89 T 09-03-2017 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 SUPERFAMILY SSF46548 560 665 1.1E-16 T 09-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 PRINTS PR00419 Adrenodoxin reductase family signature 680 693 1.4E-14 T 09-03-2017 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 PRINTS PR00419 Adrenodoxin reductase family signature 657 679 1.4E-14 T 09-03-2017 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 PRINTS PR00419 Adrenodoxin reductase family signature 789 803 1.4E-14 T 09-03-2017 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 Gene3D G3DSA:1.10.1060.10 1004 1055 3.8E-9 T 09-03-2017 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 Gene3D G3DSA:1.10.1060.10 565 656 5.5E-24 T 09-03-2017 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 Gene3D G3DSA:3.50.50.60 657 753 8.3E-19 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 475 486 - T 09-03-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 Gene3D G3DSA:3.50.50.60 890 983 2.8E-4 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS00165 9cd564a820c35cf7762c0890a3171c2f 1064 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 182 352 1.1E-47 T 09-03-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 269 277 - T 09-03-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 Gene3D G3DSA:3.40.50.720 139 273 3.4E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 7.7E-43 T 09-03-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 290 3.3E-68 T 09-03-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 SUPERFAMILY SSF51735 122 288 8.78E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 SUPERFAMILY SSF53223 1 121 2.49E-42 T 09-03-2017 L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 292 40.436 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 Gene3D G3DSA:3.40.192.10 7 138 1.6E-53 T 09-03-2017 L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 265 283 1.1E-86 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.1E-86 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 248 264 1.1E-86 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.1E-86 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.1E-86 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.1E-86 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 L21SP3_RS04015 b398c04a7379560cdef1a547c9eb338c 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 207 236 1.1E-86 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 L21SP3_RS05820 1b273001b978526eba14fa6a645c5efd 331 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 80 3.2E-20 T 09-03-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 L21SP3_RS05820 1b273001b978526eba14fa6a645c5efd 331 SUPERFAMILY SSF46589 14 98 5.23E-17 T 09-03-2017 IPR010978 tRNA-binding arm GO:0000166 L21SP3_RS05820 1b273001b978526eba14fa6a645c5efd 331 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 331 8.4E-94 T 09-03-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 L21SP3_RS05820 1b273001b978526eba14fa6a645c5efd 331 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 331 43.913 T 09-03-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 L21SP3_RS05820 1b273001b978526eba14fa6a645c5efd 331 Pfam PF01409 tRNA synthetases class II core domain (F) 93 331 9.2E-95 T 09-03-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 L21SP3_RS05820 1b273001b978526eba14fa6a645c5efd 331 SUPERFAMILY SSF55681 93 331 9.29E-74 T 09-03-2017 L21SP3_RS05820 1b273001b978526eba14fa6a645c5efd 331 Gene3D G3DSA:3.30.930.10 10 331 1.4E-118 T 09-03-2017 L21SP3_RS04150 bb334d6dfd64560b215d54148b81e899 597 Pfam PF01432 Peptidase family M3 203 576 7.5E-42 T 09-03-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 L21SP3_RS04150 bb334d6dfd64560b215d54148b81e899 597 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 50 594 3.0E-154 T 09-03-2017 IPR011976 Peptidase M3B, oligoendopeptidase-related clade 2 L21SP3_RS04150 bb334d6dfd64560b215d54148b81e899 597 Gene3D G3DSA:3.40.390.10 385 427 1.7E-4 T 09-03-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 L21SP3_RS04150 bb334d6dfd64560b215d54148b81e899 597 Gene3D G3DSA:1.10.1370.10 206 305 8.5E-10 T 09-03-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 L21SP3_RS04150 bb334d6dfd64560b215d54148b81e899 597 SUPERFAMILY SSF55486 50 577 2.93E-70 T 09-03-2017 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 SUPERFAMILY SSF57783 697 751 5.95E-10 T 09-03-2017 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 643 1.7E-238 T 09-03-2017 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Pfam PF01751 Toprim domain 5 113 3.4E-29 T 09-03-2017 IPR006171 Toprim domain L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 613 646 3.0E-11 T 09-03-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 660 696 1.4E-14 T 09-03-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 712 748 3.6E-11 T 09-03-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Pfam PF01131 DNA topoisomerase 128 582 2.2E-128 T 09-03-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Gene3D G3DSA:2.70.20.10 354 491 5.6E-32 T 09-03-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Gene3D G3DSA:2.70.20.10 238 350 4.7E-27 T 09-03-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Gene3D G3DSA:2.70.20.10 184 200 4.7E-27 T 09-03-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 SUPERFAMILY SSF57783 608 643 1.26E-9 T 09-03-2017 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 SMART SM00437 279 545 3.4E-118 T 09-03-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 728 55.121 T 09-03-2017 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 316 339 - T 09-03-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 SUPERFAMILY SSF56712 247 596 7.59E-191 T 09-03-2017 IPR023405 DNA topoisomerase, type IA, core domain L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 SUPERFAMILY SSF56712 2 200 7.59E-191 T 09-03-2017 IPR023405 DNA topoisomerase, type IA, core domain L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 SUPERFAMILY SSF56712 660 671 7.59E-191 T 09-03-2017 IPR023405 DNA topoisomerase, type IA, core domain L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Gene3D G3DSA:1.10.460.10 492 596 2.8E-60 T 09-03-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Gene3D G3DSA:1.10.460.10 135 182 2.8E-60 T 09-03-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Gene3D G3DSA:3.40.50.140 2 134 1.4E-44 T 09-03-2017 IPR006171 Toprim domain L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Gene3D G3DSA:3.30.65.10 659 695 2.2E-14 T 09-03-2017 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Gene3D G3DSA:3.30.65.10 698 748 3.6E-11 T 09-03-2017 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 Gene3D G3DSA:3.30.65.10 604 645 2.2E-11 T 09-03-2017 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 SMART SM00436 104 192 1.3E-45 T 09-03-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 2.7E-37 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 508 522 2.7E-37 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 330 339 2.7E-37 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 2.7E-37 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 407 423 2.7E-37 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 SMART SM00493 3 103 2.8E-32 T 09-03-2017 IPR006171 Toprim domain L21SP3_RS00260 cf46731008ba3ef19225941c15674d30 820 SUPERFAMILY SSF57783 657 694 4.42E-11 T 09-03-2017 L21SP3_RS02075 32611400bc958adecaea8dd934057622 189 Pfam PF01195 Peptidyl-tRNA hydrolase 5 184 7.1E-57 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 L21SP3_RS02075 32611400bc958adecaea8dd934057622 189 SUPERFAMILY SSF53178 3 186 2.49E-62 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 L21SP3_RS02075 32611400bc958adecaea8dd934057622 189 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 16 29 - T 09-03-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 L21SP3_RS02075 32611400bc958adecaea8dd934057622 189 Gene3D G3DSA:3.40.50.1470 3 188 5.2E-69 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 L21SP3_RS02075 32611400bc958adecaea8dd934057622 189 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 3 179 33.979 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 L21SP3_RS02075 32611400bc958adecaea8dd934057622 189 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 109 119 - T 09-03-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 L21SP3_RS02075 32611400bc958adecaea8dd934057622 189 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 4 187 5.2E-60 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 L21SP3_RS00030 d9b2b824ddcc1b99d81cc35429be6ca6 422 SUPERFAMILY SSF55205 1 420 2.94E-129 T 09-03-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 L21SP3_RS00030 d9b2b824ddcc1b99d81cc35429be6ca6 422 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 410 8.4E-103 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 L21SP3_RS00030 d9b2b824ddcc1b99d81cc35429be6ca6 422 Gene3D G3DSA:3.65.10.10 21 225 1.2E-58 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 L21SP3_RS00030 d9b2b824ddcc1b99d81cc35429be6ca6 422 Gene3D G3DSA:3.65.10.10 226 419 2.4E-55 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 L21SP3_RS00030 d9b2b824ddcc1b99d81cc35429be6ca6 422 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 419 4.0E-164 T 09-03-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS00030 d9b2b824ddcc1b99d81cc35429be6ca6 422 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 420 42.031 T 09-03-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 Pfam PF16355 Domain of unknown function (DUF4982) 614 674 2.1E-14 T 09-03-2017 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 302 501 1.6E-29 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 34 179 1.5E-25 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 Gene3D G3DSA:2.60.120.260 27 171 3.4E-44 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 Pfam PF00703 Glycosyl hydrolases family 2 185 294 1.3E-18 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 SUPERFAMILY SSF49303 188 294 9.21E-18 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 Gene3D G3DSA:2.60.40.1560 606 691 2.8E-14 T 09-03-2017 L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 PRINTS PR00132 Glycosyl hydrolase family 2 signature 113 128 1.3E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 PRINTS PR00132 Glycosyl hydrolase family 2 signature 306 320 1.3E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 PRINTS PR00132 Glycosyl hydrolase family 2 signature 337 355 1.3E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 PRINTS PR00132 Glycosyl hydrolase family 2 signature 404 419 1.3E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 SUPERFAMILY SSF51445 291 576 2.27E-63 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 404 418 - T 09-03-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 SUPERFAMILY SSF49785 15 182 3.77E-44 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 Gene3D G3DSA:2.60.40.320 172 294 1.1E-27 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS08660 66292eb7bfedfe4b2e307af3569b969f 796 Gene3D G3DSA:3.20.20.80 299 578 6.6E-69 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS04960 19573d9c79370ea3d682357a3f24ddb7 719 SUPERFAMILY SSF48726 356 455 5.27E-14 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS04960 19573d9c79370ea3d682357a3f24ddb7 719 SUPERFAMILY SSF49899 455 668 4.75E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04960 19573d9c79370ea3d682357a3f24ddb7 719 SMART SM00408 368 443 8.4E-7 T 09-03-2017 IPR003598 Immunoglobulin subtype 2 L21SP3_RS04960 19573d9c79370ea3d682357a3f24ddb7 719 Gene3D G3DSA:2.60.40.10 356 455 8.3E-13 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS04960 19573d9c79370ea3d682357a3f24ddb7 719 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 517 663 3.3E-19 T 09-03-2017 L21SP3_RS04960 19573d9c79370ea3d682357a3f24ddb7 719 SMART SM00409 362 455 9.8E-7 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS04960 19573d9c79370ea3d682357a3f24ddb7 719 Gene3D G3DSA:2.60.120.200 456 671 6.4E-22 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04960 19573d9c79370ea3d682357a3f24ddb7 719 Pfam PF13927 Immunoglobulin domain 356 440 3.7E-9 T 09-03-2017 L21SP3_RS04960 19573d9c79370ea3d682357a3f24ddb7 719 SMART SM00560 523 661 0.0046 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS05955 dd38ad0c67dacf27cccf750ff2d3f70b 188 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 31 4.7E-4 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS05955 dd38ad0c67dacf27cccf750ff2d3f70b 188 SUPERFAMILY SSF54523 11 84 3.37E-5 T 09-03-2017 L21SP3_RS01340 d8b8d07965888dced0a44484db883326 287 SUPERFAMILY SSF109998 4 160 6.67E-15 T 09-03-2017 IPR027304 Trigger factor/SurA domain L21SP3_RS01340 d8b8d07965888dced0a44484db883326 287 Pfam PF13616 PPIC-type PPIASE domain 144 243 2.3E-23 T 09-03-2017 L21SP3_RS01340 d8b8d07965888dced0a44484db883326 287 SUPERFAMILY SSF54534 142 245 1.64E-30 T 09-03-2017 L21SP3_RS01340 d8b8d07965888dced0a44484db883326 287 Gene3D G3DSA:3.10.50.40 138 266 4.6E-42 T 09-03-2017 L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 SUPERFAMILY SSF54980 401 495 2.12E-21 T 09-03-2017 IPR009022 Elongation factor G, III-V domain L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 SUPERFAMILY SSF50447 167 289 2.91E-29 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 Gene3D G3DSA:2.40.30.10 195 290 3.7E-24 T 09-03-2017 L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 09-03-2017 IPR031157 Tr-type G domain, conserved site L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 SUPERFAMILY SSF54980 295 371 8.99E-15 T 09-03-2017 IPR009022 Elongation factor G, III-V domain L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 TIGRFAM TIGR01393 lepA: elongation factor 4 5 596 5.8E-276 T 09-03-2017 IPR006297 Elongation factor 4 GO:0005525 L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 Gene3D G3DSA:3.30.70.240 402 491 9.0E-19 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 Gene3D G3DSA:3.40.50.300 4 194 2.6E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 SUPERFAMILY SSF52540 2 200 2.38E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 Pfam PF06421 GTP-binding protein LepA C-terminus 489 595 1.8E-46 T 09-03-2017 IPR013842 GTP-binding protein LepA, C-terminal L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 Gene3D G3DSA:3.30.70.870 295 370 2.1E-20 T 09-03-2017 L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 SMART SM00838 402 485 0.0079 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 176 4.7E-20 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 Hamap MF_00071 Elongation factor 4 [lepA]. 1 598 257.318 T 09-03-2017 IPR006297 Elongation factor 4 GO:0005525 L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 Pfam PF00679 Elongation factor G C-terminus 401 486 1.1E-19 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 Pfam PF00009 Elongation factor Tu GTP binding domain 5 182 2.1E-51 T 09-03-2017 L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 PRINTS PR00315 GTP-binding elongation factor signature 51 59 2.5E-14 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 PRINTS PR00315 GTP-binding elongation factor signature 8 21 2.5E-14 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 PRINTS PR00315 GTP-binding elongation factor signature 127 136 2.5E-14 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 PRINTS PR00315 GTP-binding elongation factor signature 75 85 2.5E-14 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 PRINTS PR00315 GTP-binding elongation factor signature 91 102 2.5E-14 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS03000 0359cc1118baefbf2cfecf55cc5025b8 598 Pfam PF03144 Elongation factor Tu domain 2 206 276 6.5E-11 T 09-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 L21SP3_RS02445 49b1154a0dd9db0415e5970d336bbae6 516 Pfam PF08502 LeuA allosteric (dimerisation) domain 370 502 4.0E-38 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 L21SP3_RS02445 49b1154a0dd9db0415e5970d336bbae6 516 Pfam PF00682 HMGL-like 4 274 1.3E-94 T 09-03-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 L21SP3_RS02445 49b1154a0dd9db0415e5970d336bbae6 516 SMART SM00917 370 503 1.8E-40 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 L21SP3_RS02445 49b1154a0dd9db0415e5970d336bbae6 516 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 09-03-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 L21SP3_RS02445 49b1154a0dd9db0415e5970d336bbae6 516 SUPERFAMILY SSF110921 401 502 2.88E-25 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 L21SP3_RS02445 49b1154a0dd9db0415e5970d336bbae6 516 Gene3D G3DSA:3.20.20.70 1 348 2.5E-147 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS02445 49b1154a0dd9db0415e5970d336bbae6 516 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 500 9.1E-220 T 09-03-2017 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 L21SP3_RS02445 49b1154a0dd9db0415e5970d336bbae6 516 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 512 43.178 T 09-03-2017 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 L21SP3_RS02445 49b1154a0dd9db0415e5970d336bbae6 516 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 09-03-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 L21SP3_RS02445 49b1154a0dd9db0415e5970d336bbae6 516 SUPERFAMILY SSF51569 1 292 2.05E-97 T 09-03-2017 L21SP3_RS05740 1144f303b92679a5ed85d9b5b8a0b2df 79 Pfam PF04023 FeoA domain 6 75 9.2E-19 T 09-03-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 L21SP3_RS05740 1144f303b92679a5ed85d9b5b8a0b2df 79 SUPERFAMILY SSF50037 7 76 3.66E-14 T 09-03-2017 IPR008988 Transcriptional repressor, C-terminal L21SP3_RS05740 1144f303b92679a5ed85d9b5b8a0b2df 79 Gene3D G3DSA:2.30.30.90 27 75 4.1E-4 T 09-03-2017 L21SP3_RS05740 1144f303b92679a5ed85d9b5b8a0b2df 79 SMART SM00899 5 76 6.2E-16 T 09-03-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 L21SP3_RS03590 7e3f1f41835f128b7992421375a14d57 256 Pfam PF02424 ApbE family 100 223 5.4E-18 T 09-03-2017 IPR024932 Flavin transferase ApbE GO:0017013 L21SP3_RS03590 7e3f1f41835f128b7992421375a14d57 256 Pfam PF02424 ApbE family 12 95 2.7E-10 T 09-03-2017 IPR024932 Flavin transferase ApbE GO:0017013 L21SP3_RS03590 7e3f1f41835f128b7992421375a14d57 256 SUPERFAMILY SSF143631 6 225 5.49E-37 T 09-03-2017 IPR003374 ApbE-like domain L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 SUPERFAMILY SSF52540 4 164 2.56E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 126 1.1E-26 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 177 345 3.4E-24 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 Hamap MF_00195 GTPase Der [der]. 3 439 32.499 T 09-03-2017 IPR016484 GTP-binding protein EngA GO:0005525 L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 SUPERFAMILY SSF52540 139 439 1.08E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 4.5E-8 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 74 92 4.5E-8 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 PIRSF PIRSF006485 2 444 4.8E-134 T 09-03-2017 IPR016484 GTP-binding protein EngA GO:0005525 L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 436 2.2E-137 T 09-03-2017 IPR016484 GTP-binding protein EngA GO:0005525 L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 358 436 3.7E-20 T 09-03-2017 IPR032859 GTPase Der, C-terminal KH-domain-like L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 Gene3D G3DSA:3.30.300.20 359 438 1.6E-21 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 Pfam PF01926 50S ribosome-binding GTPase 5 121 4.6E-25 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 Pfam PF01926 50S ribosome-binding GTPase 178 296 2.0E-23 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 Gene3D G3DSA:3.40.50.300 4 163 5.7E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10630 a0ed09cec0acc417a452783e00a052fa 456 Gene3D G3DSA:3.40.50.300 173 358 6.5E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03105 e7f22e2a5542e80fcdd6cb51e07df90b 167 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 9 165 1.5E-57 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 L21SP3_RS03105 e7f22e2a5542e80fcdd6cb51e07df90b 167 Pfam PF00731 AIR carboxylase 9 156 9.8E-58 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 L21SP3_RS03105 e7f22e2a5542e80fcdd6cb51e07df90b 167 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 8 162 29.866 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 L21SP3_RS03105 e7f22e2a5542e80fcdd6cb51e07df90b 167 PIRSF PIRSF001338 3 167 3.7E-64 T 09-03-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 L21SP3_RS03105 e7f22e2a5542e80fcdd6cb51e07df90b 167 SMART SM01001 6 158 9.0E-85 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 L21SP3_RS03105 e7f22e2a5542e80fcdd6cb51e07df90b 167 SUPERFAMILY SSF52255 8 164 3.4E-57 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 L21SP3_RS03105 e7f22e2a5542e80fcdd6cb51e07df90b 167 Gene3D G3DSA:3.40.50.7700 4 165 1.0E-64 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 SUPERFAMILY SSF49303 187 287 6.91E-17 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 Gene3D G3DSA:3.20.20.80 290 595 1.1E-67 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 Gene3D G3DSA:2.70.98.10 693 744 8.1E-4 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 39 184 7.7E-18 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 Gene3D G3DSA:2.60.40.320 187 287 1.0E-19 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 SUPERFAMILY SSF51445 566 593 3.3E-60 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 SUPERFAMILY SSF51445 284 535 3.3E-60 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 289 489 3.0E-44 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 PRINTS PR00132 Glycosyl hydrolase family 2 signature 398 413 2.3E-18 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 PRINTS PR00132 Glycosyl hydrolase family 2 signature 329 347 2.3E-18 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 PRINTS PR00132 Glycosyl hydrolase family 2 signature 298 312 2.3E-18 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 PRINTS PR00132 Glycosyl hydrolase family 2 signature 110 125 2.3E-18 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 SUPERFAMILY SSF49785 36 184 7.51E-37 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 Pfam PF00703 Glycosyl hydrolases family 2 187 287 5.7E-14 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS10935 c4b3d33d9f309df8dfcda4926b0bb370 975 Gene3D G3DSA:2.60.120.260 30 184 6.2E-40 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS02650 0e790d819482ec758d0bec3288a856f5 733 Pfam PF00580 UvrD/REP helicase N-terminal domain 17 275 1.1E-71 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 L21SP3_RS02650 0e790d819482ec758d0bec3288a856f5 733 Gene3D G3DSA:1.10.486.10 393 546 2.3E-44 T 09-03-2017 L21SP3_RS02650 0e790d819482ec758d0bec3288a856f5 733 Gene3D G3DSA:3.40.50.300 193 290 1.8E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02650 0e790d819482ec758d0bec3288a856f5 733 Gene3D G3DSA:3.40.50.300 14 114 1.8E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02650 0e790d819482ec758d0bec3288a856f5 733 Gene3D G3DSA:1.10.10.160 118 192 8.9E-21 T 09-03-2017 IPR013986 DExx box DNA helicase domain L21SP3_RS02650 0e790d819482ec758d0bec3288a856f5 733 Pfam PF13361 UvrD-like helicase C-terminal domain 282 622 1.0E-69 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 L21SP3_RS02650 0e790d819482ec758d0bec3288a856f5 733 Gene3D G3DSA:3.40.50.300 558 642 1.2E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02650 0e790d819482ec758d0bec3288a856f5 733 Gene3D G3DSA:3.40.50.300 291 392 1.2E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02650 0e790d819482ec758d0bec3288a856f5 733 SUPERFAMILY SSF52540 15 641 2.88E-161 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09660 4244e64a91feab4cd3a29900592293a2 310 Gene3D G3DSA:3.30.700.10 30 84 2.5E-6 T 09-03-2017 L21SP3_RS09660 4244e64a91feab4cd3a29900592293a2 310 Pfam PF13633 Prokaryotic N-terminal methylation site 28 53 5.5E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS09660 4244e64a91feab4cd3a29900592293a2 310 SUPERFAMILY SSF54523 30 108 3.53E-15 T 09-03-2017 L21SP3_RS09660 4244e64a91feab4cd3a29900592293a2 310 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 28 48 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS09660 4244e64a91feab4cd3a29900592293a2 310 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 28 49 1.7E-6 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS10360 e34de74bc293bbed38d5f69b0fb03a3b 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.6E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS10360 e34de74bc293bbed38d5f69b0fb03a3b 422 Pfam PF01609 Transposase DDE domain 275 412 1.5E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS11660 e34de74bc293bbed38d5f69b0fb03a3b 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.6E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS11660 e34de74bc293bbed38d5f69b0fb03a3b 422 Pfam PF01609 Transposase DDE domain 275 412 1.5E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS08795 e34de74bc293bbed38d5f69b0fb03a3b 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.6E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS08795 e34de74bc293bbed38d5f69b0fb03a3b 422 Pfam PF01609 Transposase DDE domain 275 412 1.5E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS07170 e34de74bc293bbed38d5f69b0fb03a3b 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.6E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS07170 e34de74bc293bbed38d5f69b0fb03a3b 422 Pfam PF01609 Transposase DDE domain 275 412 1.5E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 SUPERFAMILY SSF52540 7 294 1.04E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 Pfam PF00270 DEAD/DEAH box helicase 547 705 3.5E-13 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 SMART SM01058 420 517 7.8E-29 T 09-03-2017 IPR003711 CarD-like/TRCF domain L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 SUPERFAMILY SSF143517 930 1043 5.49E-27 T 09-03-2017 L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 SMART SM00487 541 728 1.6E-27 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 SUPERFAMILY SSF141259 414 489 1.12E-17 T 09-03-2017 IPR003711 CarD-like/TRCF domain L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 Pfam PF03461 TRCF domain 946 1033 4.0E-22 T 09-03-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 Pfam PF02559 CarD-like/TRCF domain 421 515 1.1E-20 T 09-03-2017 IPR003711 CarD-like/TRCF domain L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 SMART SM00490 767 851 9.1E-21 T 09-03-2017 IPR001650 Helicase, C-terminal L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 SUPERFAMILY SSF52540 335 407 3.39E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 33 1051 26.796 T 09-03-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 309 1017 5.0E-278 T 09-03-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 SUPERFAMILY SSF52540 593 863 3.01E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 Gene3D G3DSA:3.40.50.300 532 727 4.5E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 Pfam PF00271 Helicase conserved C-terminal domain 746 850 4.3E-17 T 09-03-2017 IPR001650 Helicase, C-terminal L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 Gene3D G3DSA:3.30.2060.10 131 216 4.4E-9 T 09-03-2017 L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 SMART SM00982 944 1043 1.8E-27 T 09-03-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 L21SP3_RS05240 e8ae0f5bc99d00b9995ae6df19dc48f8 1080 Gene3D G3DSA:3.40.50.300 743 897 6.5E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09520 6a35571e332f89591f4d88876b62bcb9 256 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 73 217 3.3E-16 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS09520 6a35571e332f89591f4d88876b62bcb9 256 Gene3D G3DSA:3.40.50.1110 32 227 9.7E-38 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS09520 6a35571e332f89591f4d88876b62bcb9 256 SUPERFAMILY SSF52266 35 225 4.93E-39 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS10950 4617ab6f145388570ebbf4a9d6a193b7 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 327 2.8E-32 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 L21SP3_RS10950 4617ab6f145388570ebbf4a9d6a193b7 333 Gene3D G3DSA:3.40.50.720 142 305 9.8E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS10950 4617ab6f145388570ebbf4a9d6a193b7 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 09-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 L21SP3_RS10950 4617ab6f145388570ebbf4a9d6a193b7 333 SUPERFAMILY SSF52283 2 135 3.83E-40 T 09-03-2017 L21SP3_RS10950 4617ab6f145388570ebbf4a9d6a193b7 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 297 2.0E-53 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 L21SP3_RS10950 4617ab6f145388570ebbf4a9d6a193b7 333 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 194 216 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site L21SP3_RS10950 4617ab6f145388570ebbf4a9d6a193b7 333 SUPERFAMILY SSF51735 102 298 6.14E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS10950 4617ab6f145388570ebbf4a9d6a193b7 333 Gene3D G3DSA:3.40.50.720 1 141 6.1E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS07010 312ea036d812a4526be154dae624aba8 509 Gene3D G3DSA:3.60.21.10 222 503 5.5E-19 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS07010 312ea036d812a4526be154dae624aba8 509 Pfam PF09423 PhoD-like phosphatase 250 454 2.8E-12 T 09-03-2017 IPR018946 Alkaline phosphatase D-related L21SP3_RS07010 312ea036d812a4526be154dae624aba8 509 SUPERFAMILY SSF56300 203 428 1.17E-22 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS06210 fbed19312237285a120d04123c194cad 219 Gene3D G3DSA:2.40.30.10 164 216 4.7E-8 T 09-03-2017 L21SP3_RS06210 fbed19312237285a120d04123c194cad 219 Gene3D G3DSA:2.40.30.10 4 32 4.7E-8 T 09-03-2017 L21SP3_RS06210 fbed19312237285a120d04123c194cad 219 Gene3D G3DSA:4.10.960.10 79 163 3.1E-22 T 09-03-2017 L21SP3_RS06210 fbed19312237285a120d04123c194cad 219 Pfam PF00297 Ribosomal protein L3 99 189 6.0E-12 T 09-03-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06210 fbed19312237285a120d04123c194cad 219 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 210 2.4E-76 T 09-03-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06210 fbed19312237285a120d04123c194cad 219 ProSitePatterns PS00474 Ribosomal protein L3 signature. 103 126 - T 09-03-2017 IPR019926 Ribosomal protein L3, conserved site L21SP3_RS06210 fbed19312237285a120d04123c194cad 219 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 213 36.631 T 09-03-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06210 fbed19312237285a120d04123c194cad 219 SUPERFAMILY SSF50447 2 216 6.0E-69 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain L21SP3_RS04130 bb85f43d399aa1fb74e307b17916f584 93 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.213 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04130 bb85f43d399aa1fb74e307b17916f584 93 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 26 88 1.0E-10 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04130 bb85f43d399aa1fb74e307b17916f584 93 SUPERFAMILY SSF46992 6 86 7.85E-27 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04130 bb85f43d399aa1fb74e307b17916f584 93 Pfam PF01649 Ribosomal protein S20 2 83 5.6E-26 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04130 bb85f43d399aa1fb74e307b17916f584 93 Gene3D G3DSA:1.20.58.110 2 86 1.7E-27 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04130 bb85f43d399aa1fb74e307b17916f584 93 TIGRFAM TIGR00029 S20: ribosomal protein bS20 4 86 3.9E-23 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS05365 71db021e3999aac38e8ebebc9dd99fd5 600 SUPERFAMILY SSF48208 204 588 1.51E-89 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS05365 71db021e3999aac38e8ebebc9dd99fd5 600 Gene3D G3DSA:1.50.10.10 216 586 3.8E-74 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS05365 71db021e3999aac38e8ebebc9dd99fd5 600 Pfam PF00723 Glycosyl hydrolases family 15 224 526 3.2E-38 T 09-03-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 Pfam PF11987 Translation-initiation factor 2 702 806 2.1E-33 T 09-03-2017 IPR023115 Translation initiation factor IF- 2, domain 3 L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 SUPERFAMILY SSF50447 590 670 3.93E-19 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 SUPERFAMILY SSF52540 400 588 1.54E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 Gene3D G3DSA:3.40.50.300 405 576 1.2E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 20 64 8.5E-12 T 09-03-2017 IPR006847 Translation initiation factor IF-2, N-terminal L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 340 390 8.7E-12 T 09-03-2017 IPR006847 Translation initiation factor IF-2, N-terminal L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 SUPERFAMILY SSF50447 819 915 1.12E-29 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 420 573 3.9E-33 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 17 915 15.851 T 09-03-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 Gene3D G3DSA:2.40.30.10 591 679 2.7E-15 T 09-03-2017 L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 Gene3D G3DSA:2.40.30.10 819 916 5.0E-33 T 09-03-2017 L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 Pfam PF00009 Elongation factor Tu GTP binding domain 420 577 2.4E-30 T 09-03-2017 L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 Gene3D G3DSA:3.40.50.10050 717 795 4.3E-22 T 09-03-2017 IPR023115 Translation initiation factor IF- 2, domain 3 L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 333 917 6.9E-219 T 09-03-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 L21SP3_RS10180 aac2f7102d34a263649f5a5fb9809086 918 SUPERFAMILY SSF52156 694 823 1.57E-34 T 09-03-2017 IPR023115 Translation initiation factor IF- 2, domain 3 L21SP3_RS02300 005b71c90c4e3c94b2605f114829f445 122 Pfam PF00717 Peptidase S24-like 38 105 8.7E-15 T 09-03-2017 IPR019759 Peptidase S24/S26A/S26B L21SP3_RS02300 005b71c90c4e3c94b2605f114829f445 122 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 35 45 1.7E-10 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 L21SP3_RS02300 005b71c90c4e3c94b2605f114829f445 122 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 46 57 1.7E-10 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 L21SP3_RS02300 005b71c90c4e3c94b2605f114829f445 122 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 74 86 1.7E-10 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 L21SP3_RS02300 005b71c90c4e3c94b2605f114829f445 122 SUPERFAMILY SSF51306 17 120 9.94E-32 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C L21SP3_RS02300 005b71c90c4e3c94b2605f114829f445 122 Gene3D G3DSA:2.10.109.10 17 122 7.0E-40 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 SUPERFAMILY SSF52777 331 550 6.67E-59 T 09-03-2017 L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 SUPERFAMILY SSF51230 3 82 4.71E-22 T 09-03-2017 IPR011053 Single hybrid motif L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 331 552 7.0E-61 T 09-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 SUPERFAMILY SSF51230 191 269 4.97E-18 T 09-03-2017 IPR011053 Single hybrid motif L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 Pfam PF00364 Biotin-requiring enzyme 4 76 2.2E-20 T 09-03-2017 IPR000089 Biotin/lipoyl attachment L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 Pfam PF00364 Biotin-requiring enzyme 91 161 3.3E-13 T 09-03-2017 IPR000089 Biotin/lipoyl attachment L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 Pfam PF00364 Biotin-requiring enzyme 191 262 1.1E-15 T 09-03-2017 IPR000089 Biotin/lipoyl attachment L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 SUPERFAMILY SSF51230 88 167 3.66E-15 T 09-03-2017 IPR011053 Single hybrid motif L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 214 243 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 112 141 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 Gene3D G3DSA:2.40.50.100 4 77 1.5E-24 T 09-03-2017 L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 Gene3D G3DSA:3.30.559.10 324 550 1.2E-61 T 09-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 Gene3D G3DSA:2.40.50.100 90 167 5.0E-15 T 09-03-2017 L21SP3_RS03575 d306e527eb1d63c857afc4ee04b04414 554 Gene3D G3DSA:2.40.50.100 191 276 1.3E-19 T 09-03-2017 L21SP3_RS02520 3c2dc0922d4ad82d7c0dffd722b0581b 854 Gene3D G3DSA:3.40.50.1970 445 636 1.4E-62 T 09-03-2017 L21SP3_RS02520 3c2dc0922d4ad82d7c0dffd722b0581b 854 SUPERFAMILY SSF56796 443 853 9.42E-122 T 09-03-2017 L21SP3_RS02520 3c2dc0922d4ad82d7c0dffd722b0581b 854 Gene3D G3DSA:3.40.605.10 3 202 4.2E-26 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 L21SP3_RS02520 3c2dc0922d4ad82d7c0dffd722b0581b 854 PIRSF PIRSF000111 1 854 0.0 T 09-03-2017 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00592+1.1.1.1|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00650+1.2.1.10|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7085|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7180|MetaCyc: PWY-7396 L21SP3_RS02520 3c2dc0922d4ad82d7c0dffd722b0581b 854 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 625 653 - T 09-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 L21SP3_RS02520 3c2dc0922d4ad82d7c0dffd722b0581b 854 SUPERFAMILY SSF53720 4 448 2.23E-81 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 L21SP3_RS02520 3c2dc0922d4ad82d7c0dffd722b0581b 854 Gene3D G3DSA:3.40.309.10 305 398 6.4E-28 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 L21SP3_RS02520 3c2dc0922d4ad82d7c0dffd722b0581b 854 Gene3D G3DSA:3.40.309.10 211 269 6.4E-28 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 L21SP3_RS02520 3c2dc0922d4ad82d7c0dffd722b0581b 854 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 713 733 - T 09-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 L21SP3_RS02520 3c2dc0922d4ad82d7c0dffd722b0581b 854 Gene3D G3DSA:1.20.1090.10 637 854 8.9E-72 T 09-03-2017 L21SP3_RS02520 3c2dc0922d4ad82d7c0dffd722b0581b 854 Pfam PF00465 Iron-containing alcohol dehydrogenase 452 841 3.6E-117 T 09-03-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 L21SP3_RS02520 3c2dc0922d4ad82d7c0dffd722b0581b 854 Pfam PF00171 Aldehyde dehydrogenase family 3 396 8.1E-31 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 L21SP3_RS08210 44e94378bc8f8d0f53296150cbb493dc 396 SUPERFAMILY SSF54826 36 145 2.53E-12 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS08210 44e94378bc8f8d0f53296150cbb493dc 396 Gene3D G3DSA:3.20.20.120 149 390 7.5E-34 T 09-03-2017 IPR029065 Enolase C-terminal domain-like L21SP3_RS08210 44e94378bc8f8d0f53296150cbb493dc 396 SMART SM00922 173 273 3.5E-6 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal L21SP3_RS08210 44e94378bc8f8d0f53296150cbb493dc 396 Pfam PF13378 Enolase C-terminal domain-like 187 393 4.2E-25 T 09-03-2017 IPR029065 Enolase C-terminal domain-like L21SP3_RS08210 44e94378bc8f8d0f53296150cbb493dc 396 Gene3D G3DSA:3.30.390.10 34 148 1.8E-12 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 L21SP3_RS08210 44e94378bc8f8d0f53296150cbb493dc 396 SUPERFAMILY SSF51604 133 393 1.57E-32 T 09-03-2017 IPR029065 Enolase C-terminal domain-like L21SP3_RS06740 c5456ab8a38d551ba9bdc6788cafceb5 217 Pfam PF00578 AhpC/TSA family 12 139 7.5E-27 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 L21SP3_RS06740 c5456ab8a38d551ba9bdc6788cafceb5 217 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 198 2.4E-5 T 09-03-2017 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 L21SP3_RS06740 c5456ab8a38d551ba9bdc6788cafceb5 217 Hamap MF_00401 Peroxiredoxin. 9 214 46.279 T 09-03-2017 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 L21SP3_RS06740 c5456ab8a38d551ba9bdc6788cafceb5 217 SUPERFAMILY SSF52833 7 214 9.84E-57 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS06740 c5456ab8a38d551ba9bdc6788cafceb5 217 Gene3D G3DSA:3.40.30.10 11 159 2.9E-52 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS06740 c5456ab8a38d551ba9bdc6788cafceb5 217 Gene3D G3DSA:3.30.1020.10 160 216 3.7E-14 T 09-03-2017 L21SP3_RS06740 c5456ab8a38d551ba9bdc6788cafceb5 217 PIRSF PIRSF000239 4 216 7.9E-72 T 09-03-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 L21SP3_RS00830 22ed5ab269d020cb438c12e5d3c7a4b0 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 161 1.6E-18 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS00830 22ed5ab269d020cb438c12e5d3c7a4b0 172 Pfam PF07638 ECF sigma factor 40 160 4.6E-9 T 09-03-2017 IPR011517 RNA polymerase sigma-70 ECF-like L21SP3_RS00830 22ed5ab269d020cb438c12e5d3c7a4b0 172 SUPERFAMILY SSF88946 4 89 2.43E-16 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS00830 22ed5ab269d020cb438c12e5d3c7a4b0 172 Gene3D G3DSA:1.10.10.10 103 164 1.8E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS00830 22ed5ab269d020cb438c12e5d3c7a4b0 172 SUPERFAMILY SSF88659 101 164 1.5E-6 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS00830 22ed5ab269d020cb438c12e5d3c7a4b0 172 Gene3D G3DSA:1.10.1740.10 4 94 8.5E-17 T 09-03-2017 L21SP3_RS00830 22ed5ab269d020cb438c12e5d3c7a4b0 172 TIGRFAM TIGR02989 Sig-70_gvs1: RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family 6 162 2.4E-40 T 09-03-2017 IPR014331 RNA polymerase sigma-70 ECF-like, Rhodopirellula baltica L21SP3_RS02230 e4407cba37306a4b5eb39e78a19ba5eb 363 Gene3D G3DSA:3.40.50.300 101 342 1.9E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02230 e4407cba37306a4b5eb39e78a19ba5eb 363 Pfam PF00437 Type II/IV secretion system protein 8 265 1.7E-45 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS02230 e4407cba37306a4b5eb39e78a19ba5eb 363 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 342 1.1E-125 T 09-03-2017 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 L21SP3_RS02230 e4407cba37306a4b5eb39e78a19ba5eb 363 SUPERFAMILY SSF52540 5 332 5.4E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02230 e4407cba37306a4b5eb39e78a19ba5eb 363 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS02230 e4407cba37306a4b5eb39e78a19ba5eb 363 SMART SM00382 122 255 4.5E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS01555 05ba3de5de4747e60a45cf10cf2f5c8c 215 Gene3D G3DSA:3.40.50.720 74 208 1.4E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS01555 05ba3de5de4747e60a45cf10cf2f5c8c 215 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 2 205 27.03 T 09-03-2017 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 L21SP3_RS01555 05ba3de5de4747e60a45cf10cf2f5c8c 215 Gene3D G3DSA:1.10.10.10 6 72 6.2E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS01555 05ba3de5de4747e60a45cf10cf2f5c8c 215 Pfam PF06971 Putative DNA-binding protein N-terminus 7 50 1.9E-9 T 09-03-2017 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 L21SP3_RS01555 05ba3de5de4747e60a45cf10cf2f5c8c 215 SUPERFAMILY SSF46785 8 76 7.34E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS01555 05ba3de5de4747e60a45cf10cf2f5c8c 215 SUPERFAMILY SSF51735 80 200 4.33E-20 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS01555 05ba3de5de4747e60a45cf10cf2f5c8c 215 Pfam PF02629 CoA binding domain 81 174 1.7E-16 T 09-03-2017 IPR003781 CoA-binding GO:0048037 L21SP3_RS01555 05ba3de5de4747e60a45cf10cf2f5c8c 215 SMART SM00881 76 176 2.0E-10 T 09-03-2017 IPR003781 CoA-binding GO:0048037 L21SP3_RS00010 830bd68c6451798f0df9c4953914ed1e 240 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 50 226 1.0E-5 T 09-03-2017 IPR001707 Chloramphenicol acetyltransferase GO:0008811 L21SP3_RS00010 830bd68c6451798f0df9c4953914ed1e 240 SUPERFAMILY SSF52777 42 236 2.85E-28 T 09-03-2017 L21SP3_RS00010 830bd68c6451798f0df9c4953914ed1e 240 Gene3D G3DSA:3.30.559.10 43 235 2.3E-19 T 09-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 L21SP3_RS00010 830bd68c6451798f0df9c4953914ed1e 240 SMART SM01059 33 238 3.4E-4 T 09-03-2017 IPR001707 Chloramphenicol acetyltransferase GO:0008811 L21SP3_RS00010 830bd68c6451798f0df9c4953914ed1e 240 Pfam PF00302 Chloramphenicol acetyltransferase 41 236 4.7E-11 T 09-03-2017 IPR001707 Chloramphenicol acetyltransferase GO:0008811 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 Pfam PF08264 Anticodon-binding domain of tRNA 676 834 3.2E-39 T 09-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 50 61 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 SUPERFAMILY SSF47323 645 905 3.74E-57 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 SUPERFAMILY SSF46589 892 956 1.67E-12 T 09-03-2017 IPR010978 tRNA-binding arm GO:0000166 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 Gene3D G3DSA:3.90.740.10 202 342 3.6E-48 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 TIGRFAM TIGR00422 valS: valine--tRNA ligase 7 939 0.0 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 SUPERFAMILY SSF50677 198 348 1.83E-57 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 892 956 2.1E-14 T 09-03-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 Gene3D G3DSA:1.10.287.380 888 952 8.7E-7 T 09-03-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 SUPERFAMILY SSF52374 482 626 2.16E-124 T 09-03-2017 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 SUPERFAMILY SSF52374 348 434 2.16E-124 T 09-03-2017 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 SUPERFAMILY SSF52374 5 200 2.16E-124 T 09-03-2017 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 Hamap MF_02004 Valine--tRNA ligase [valS]. 5 956 14.941 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 Gene3D G3DSA:3.40.50.620 486 622 7.5E-129 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 Gene3D G3DSA:3.40.50.620 4 196 7.5E-129 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 Gene3D G3DSA:3.40.50.620 351 449 7.5E-129 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 Gene3D G3DSA:1.10.730.10 637 827 5.2E-55 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 20 623 1.3E-190 T 09-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 PRINTS PR00986 Valyl-tRNA synthetase signature 353 366 2.3E-32 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 PRINTS PR00986 Valyl-tRNA synthetase signature 43 54 2.3E-32 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 PRINTS PR00986 Valyl-tRNA synthetase signature 238 255 2.3E-32 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 PRINTS PR00986 Valyl-tRNA synthetase signature 536 554 2.3E-32 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 L21SP3_RS09535 b82182492570fdb9ed312544e9df3c13 956 PRINTS PR00986 Valyl-tRNA synthetase signature 505 526 2.3E-32 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 L21SP3_RS04345 f1a5b4586f8503affef66f866e5d3461 229 SUPERFAMILY SSF52540 4 224 1.95E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04345 f1a5b4586f8503affef66f866e5d3461 229 Gene3D G3DSA:3.40.50.300 2 227 4.8E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04345 f1a5b4586f8503affef66f866e5d3461 229 SMART SM00382 34 221 8.5E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS04345 f1a5b4586f8503affef66f866e5d3461 229 Pfam PF00005 ABC transporter 25 173 3.4E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS04345 f1a5b4586f8503affef66f866e5d3461 229 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS00375 cc3dbc91aff617d283455c39e5b5f698 176 Pfam PF08281 Sigma-70, region 4 111 157 4.9E-10 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS00375 cc3dbc91aff617d283455c39e5b5f698 176 Pfam PF04542 Sigma-70 region 2 19 81 5.0E-7 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS00375 cc3dbc91aff617d283455c39e5b5f698 176 SUPERFAMILY SSF88946 11 88 3.45E-12 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS00375 cc3dbc91aff617d283455c39e5b5f698 176 SUPERFAMILY SSF88659 105 167 5.79E-10 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS00375 cc3dbc91aff617d283455c39e5b5f698 176 Gene3D G3DSA:1.10.10.10 108 167 1.0E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS00375 cc3dbc91aff617d283455c39e5b5f698 176 Gene3D G3DSA:1.10.1740.10 11 100 3.7E-13 T 09-03-2017 L21SP3_RS00375 cc3dbc91aff617d283455c39e5b5f698 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 165 4.9E-22 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS00595 200882ba86559a072ecd122626ed9b22 154 Pfam PF00011 Hsp20/alpha crystallin family 53 153 1.1E-23 T 09-03-2017 IPR002068 Alpha crystallin/Hsp20 domain L21SP3_RS00595 200882ba86559a072ecd122626ed9b22 154 SUPERFAMILY SSF49764 25 149 6.28E-37 T 09-03-2017 IPR008978 HSP20-like chaperone L21SP3_RS00595 200882ba86559a072ecd122626ed9b22 154 Gene3D G3DSA:2.60.40.790 18 154 1.5E-40 T 09-03-2017 IPR008978 HSP20-like chaperone L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 SUPERFAMILY SSF54980 384 460 2.23E-15 T 09-03-2017 IPR009022 Elongation factor G, III-V domain L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 Pfam PF00679 Elongation factor G C-terminus 583 669 5.7E-26 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 Gene3D G3DSA:3.30.70.240 580 674 2.0E-28 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 Gene3D G3DSA:3.40.50.300 9 267 4.2E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 Pfam PF14492 Elongation Factor G, domain II 384 457 1.3E-20 T 09-03-2017 IPR009022 Elongation factor G, III-V domain L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 SMART SM00889 460 580 8.5E-51 T 09-03-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 SUPERFAMILY SSF54980 585 678 1.68E-25 T 09-03-2017 IPR009022 Elongation factor G, III-V domain L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 236 258 8.5E-6 T 09-03-2017 L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 119 142 8.5E-6 T 09-03-2017 L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 Gene3D G3DSA:3.30.70.870 385 460 5.4E-23 T 09-03-2017 L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 Gene3D G3DSA:3.30.230.10 464 579 2.4E-39 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 SUPERFAMILY SSF54211 459 581 1.21E-35 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 SUPERFAMILY SSF52540 10 263 5.79E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 Pfam PF00009 Elongation factor Tu GTP binding domain 12 262 7.4E-39 T 09-03-2017 L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 SMART SM00838 582 670 2.8E-33 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 Gene3D G3DSA:2.40.30.10 283 381 4.6E-20 T 09-03-2017 L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 SUPERFAMILY SSF50447 247 375 8.03E-21 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 PRINTS PR00315 GTP-binding elongation factor signature 97 108 1.6E-6 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 PRINTS PR00315 GTP-binding elongation factor signature 81 91 1.6E-6 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 PRINTS PR00315 GTP-binding elongation factor signature 15 28 1.6E-6 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 PRINTS PR00315 GTP-binding elongation factor signature 133 142 1.6E-6 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 151 2.3E-12 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP3_RS08000 741aa265c154cac89761581cd8f51428 681 Pfam PF03764 Elongation factor G, domain IV 459 580 2.6E-33 T 09-03-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 L21SP3_RS02575 884b168a26164ab68a3586c7428931ea 345 Pfam PF04338 Protein of unknown function, DUF481 132 345 6.0E-46 T 09-03-2017 IPR007433 Protein of unknown function DUF481 L21SP3_RS02575 884b168a26164ab68a3586c7428931ea 345 SUPERFAMILY SSF56935 127 315 4.03E-8 T 09-03-2017 L21SP3_RS00570 e05264a873b580740f379ba66962847b 459 SUPERFAMILY SSF101307 6 156 1.02E-22 T 09-03-2017 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 L21SP3_RS00570 e05264a873b580740f379ba66962847b 459 Pfam PF02673 Bacitracin resistance protein BacA 187 450 1.5E-55 T 09-03-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 L21SP3_RS00570 e05264a873b580740f379ba66962847b 459 Pfam PF04608 Phosphatidylglycerophosphatase A 5 156 3.2E-31 T 09-03-2017 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 L21SP3_RS00570 e05264a873b580740f379ba66962847b 459 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 181 456 14.468 T 09-03-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 Gene3D G3DSA:3.30.450.20 131 189 7.0E-11 T 09-03-2017 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 Pfam PF00072 Response regulator receiver domain 7 110 2.4E-15 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 Pfam PF00072 Response regulator receiver domain 532 641 1.2E-24 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 Gene3D G3DSA:3.30.565.10 312 482 2.3E-43 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 135 251 1.6E-6 T 09-03-2017 IPR000014 PAS domain L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 SMART SM00387 373 484 1.3E-33 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 SMART SM00388 258 326 1.2E-20 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 374 482 5.0E-27 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 SUPERFAMILY SSF52172 528 645 9.68E-34 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 Gene3D G3DSA:3.40.50.2300 4 130 8.9E-25 T 09-03-2017 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 SUPERFAMILY SSF47384 244 327 5.1E-23 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 SUPERFAMILY SSF55874 315 482 1.3E-43 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 462 3.9E-17 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 423 3.9E-17 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 437 3.9E-17 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 481 3.9E-17 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 SMART SM00448 5 125 2.9E-12 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 SMART SM00448 530 640 3.3E-32 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 326 6.5E-19 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 SUPERFAMILY SSF55785 126 243 3.66E-10 T 09-03-2017 IPR000014 PAS domain L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 SUPERFAMILY SSF52172 5 139 4.84E-19 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 Pfam PF00989 PAS fold 140 242 2.9E-5 T 09-03-2017 IPR013767 PAS fold GO:0006355 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 Gene3D G3DSA:3.40.50.2300 527 644 1.0E-35 T 09-03-2017 L21SP3_RS03670 76157c27eae7f64223a487eca46d550e 645 Gene3D G3DSA:1.10.287.130 250 311 2.4E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS03150 5d1cf6ec95eaff57a2876cd9f915fd43 277 Gene3D G3DSA:3.30.700.10 12 40 2.3E-6 T 09-03-2017 L21SP3_RS03150 5d1cf6ec95eaff57a2876cd9f915fd43 277 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 249 262 0.0012 T 09-03-2017 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP3_RS03150 5d1cf6ec95eaff57a2876cd9f915fd43 277 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 31 2.6E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS03150 5d1cf6ec95eaff57a2876cd9f915fd43 277 SUPERFAMILY SSF54523 12 90 7.85E-14 T 09-03-2017 L21SP3_RS03150 5d1cf6ec95eaff57a2876cd9f915fd43 277 Pfam PF13633 Prokaryotic N-terminal methylation site 9 35 6.9E-9 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 SUPERFAMILY SSF52540 182 490 1.22E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 Pfam PF02151 UvrB/uvrC motif 439 472 7.8E-6 T 09-03-2017 IPR001943 UVR domain GO:0005515 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 Gene3D G3DSA:3.40.50.300 183 364 2.0E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 92 144 7.1E-18 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 67 5.1E-15 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 316 328 - T 09-03-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 Gene3D G3DSA:4.10.860.10 443 472 1.8E-4 T 09-03-2017 IPR001943 UVR domain GO:0005515 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 Gene3D G3DSA:3.40.50.300 513 684 2.0E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 Gene3D G3DSA:3.40.50.300 718 746 2.0E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 Pfam PF07724 AAA domain (Cdc48 subfamily) 557 728 5.2E-54 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 Gene3D G3DSA:1.10.8.60 747 824 3.2E-29 T 09-03-2017 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 226 349 1.9E-12 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 Gene3D G3DSA:1.10.1780.10 1 146 7.2E-43 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 735 815 3.2E-24 T 09-03-2017 IPR019489 Clp ATPase, C-terminal L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 SUPERFAMILY SSF81923 3 145 2.75E-31 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 607 625 3.1E-39 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 669 683 3.1E-39 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 636 654 3.1E-39 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 562 580 3.1E-39 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 SMART SM01086 735 825 1.6E-30 T 09-03-2017 IPR019489 Clp ATPase, C-terminal L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 Gene3D G3DSA:1.10.8.60 366 442 3.6E-31 T 09-03-2017 L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 SMART SM00382 558 696 8.6E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 SMART SM00382 221 365 6.6E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS06720 8a301a09d4a5a32a4ad079e839d50b8a 834 SUPERFAMILY SSF52540 507 819 9.58E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 ProSitePatterns PS01014 Transcription termination factor nusG signature. 166 175 - T 09-03-2017 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 3 182 2.3E-45 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 Pfam PF00467 KOW motif 132 164 1.4E-5 T 09-03-2017 IPR005824 KOW L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 SUPERFAMILY SSF50104 114 182 1.29E-15 T 09-03-2017 IPR008991 Translation protein SH3-like domain L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 1 183 19.973 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 SMART SM00739 129 156 8.1E-5 T 09-03-2017 IPR005824 KOW L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 Gene3D G3DSA:2.30.30.30 122 183 1.3E-21 T 09-03-2017 IPR014722 Ribosomal protein L2 domain 2 L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 SMART SM00738 1 115 1.2E-21 T 09-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 PRINTS PR00338 Transcription termination factor NUSG signature 141 156 1.5E-12 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 PRINTS PR00338 Transcription termination factor NUSG signature 159 175 1.5E-12 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 PRINTS PR00338 Transcription termination factor NUSG signature 56 68 1.5E-12 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 Gene3D G3DSA:3.30.70.940 1 118 5.8E-32 T 09-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 SUPERFAMILY SSF82679 1 117 8.11E-28 T 09-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 L21SP3_RS10765 06dcd7891e3ba3b5498f597191552013 183 Pfam PF02357 Transcription termination factor nusG 1 112 1.9E-19 T 09-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 L21SP3_RS02000 7ab4ce94728017c63e27836c40bbfc8e 655 Pfam PF14849 YidC periplasmic domain 80 390 1.7E-6 T 09-03-2017 IPR028053 Membrane insertase YidC, N-terminal L21SP3_RS02000 7ab4ce94728017c63e27836c40bbfc8e 655 Pfam PF02096 60Kd inner membrane protein 419 624 4.0E-49 T 09-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP3_RS02000 7ab4ce94728017c63e27836c40bbfc8e 655 PRINTS PR01900 YidC translocation/secretion protein signature 404 420 9.6E-7 T 09-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP3_RS02000 7ab4ce94728017c63e27836c40bbfc8e 655 PRINTS PR01900 YidC translocation/secretion protein signature 552 567 9.6E-7 T 09-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP3_RS02000 7ab4ce94728017c63e27836c40bbfc8e 655 PRINTS PR01900 YidC translocation/secretion protein signature 579 603 9.6E-7 T 09-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 L21SP3_RS02000 7ab4ce94728017c63e27836c40bbfc8e 655 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 418 623 7.7E-53 T 09-03-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal L21SP3_RS02000 7ab4ce94728017c63e27836c40bbfc8e 655 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 14 626 13.608 T 09-03-2017 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 L21SP3_RS01205 95651ffc948bbd7921640c5e0bc4866b 555 SUPERFAMILY SSF53067 287 530 5.96E-57 T 09-03-2017 L21SP3_RS01205 95651ffc948bbd7921640c5e0bc4866b 555 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 294 485 1.5E-39 T 09-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 L21SP3_RS01205 95651ffc948bbd7921640c5e0bc4866b 555 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 2 531 1.6E-179 T 09-03-2017 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 L21SP3_RS01205 95651ffc948bbd7921640c5e0bc4866b 555 Gene3D G3DSA:3.30.420.40 286 528 1.4E-52 T 09-03-2017 L21SP3_RS01205 95651ffc948bbd7921640c5e0bc4866b 555 Gene3D G3DSA:3.30.420.40 2 283 1.7E-34 T 09-03-2017 L21SP3_RS01205 95651ffc948bbd7921640c5e0bc4866b 555 SUPERFAMILY SSF53067 3 285 7.77E-30 T 09-03-2017 L21SP3_RS01205 95651ffc948bbd7921640c5e0bc4866b 555 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 283 9.8E-14 T 09-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 L21SP3_RS01205 95651ffc948bbd7921640c5e0bc4866b 555 Hamap MF_00520 Ribulokinase [araB]. 1 542 44.935 T 09-03-2017 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 L21SP3_RS01205 95651ffc948bbd7921640c5e0bc4866b 555 PIRSF PIRSF000538 1 530 7.7E-54 T 09-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 L21SP3_RS03950 581ae7ae21f37e7deb33e0d85b0b9a27 454 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 9 446 1.1E-143 T 09-03-2017 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 L21SP3_RS03950 581ae7ae21f37e7deb33e0d85b0b9a27 454 Pfam PF10531 SLBB domain 296 343 2.2E-14 T 09-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS03950 581ae7ae21f37e7deb33e0d85b0b9a27 454 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 379 390 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS03950 581ae7ae21f37e7deb33e0d85b0b9a27 454 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 418 429 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS03950 581ae7ae21f37e7deb33e0d85b0b9a27 454 Pfam PF13237 4Fe-4S dicluster domain 375 429 3.6E-9 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS03950 581ae7ae21f37e7deb33e0d85b0b9a27 454 Gene3D G3DSA:1.10.1060.10 327 449 8.2E-16 T 09-03-2017 L21SP3_RS03950 581ae7ae21f37e7deb33e0d85b0b9a27 454 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 454 130.525 T 09-03-2017 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 L21SP3_RS03950 581ae7ae21f37e7deb33e0d85b0b9a27 454 SUPERFAMILY SSF142019 121 303 7.06E-54 T 09-03-2017 L21SP3_RS03950 581ae7ae21f37e7deb33e0d85b0b9a27 454 Gene3D G3DSA:2.40.50.100 39 90 7.0E-5 T 09-03-2017 L21SP3_RS03950 581ae7ae21f37e7deb33e0d85b0b9a27 454 Pfam PF13375 RnfC Barrel sandwich hybrid domain 9 108 1.8E-31 T 09-03-2017 IPR026902 RnfC Barrel sandwich hybrid domain L21SP3_RS03950 581ae7ae21f37e7deb33e0d85b0b9a27 454 SUPERFAMILY SSF46548 333 445 7.32E-17 T 09-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 L21SP3_RS03950 581ae7ae21f37e7deb33e0d85b0b9a27 454 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 137 281 2.6E-48 T 09-03-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS00150 f30e0257b31d92982f46323dfb5b1b0e 531 Pfam PF03023 MviN-like protein 27 484 1.4E-91 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP3_RS00150 f30e0257b31d92982f46323dfb5b1b0e 531 PRINTS PR01806 Virulence factor MviN signature 149 170 1.3E-51 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP3_RS00150 f30e0257b31d92982f46323dfb5b1b0e 531 PRINTS PR01806 Virulence factor MviN signature 375 394 1.3E-51 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP3_RS00150 f30e0257b31d92982f46323dfb5b1b0e 531 PRINTS PR01806 Virulence factor MviN signature 427 444 1.3E-51 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP3_RS00150 f30e0257b31d92982f46323dfb5b1b0e 531 PRINTS PR01806 Virulence factor MviN signature 125 149 1.3E-51 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP3_RS00150 f30e0257b31d92982f46323dfb5b1b0e 531 PRINTS PR01806 Virulence factor MviN signature 276 302 1.3E-51 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP3_RS00150 f30e0257b31d92982f46323dfb5b1b0e 531 PRINTS PR01806 Virulence factor MviN signature 31 50 1.3E-51 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP3_RS00150 f30e0257b31d92982f46323dfb5b1b0e 531 PRINTS PR01806 Virulence factor MviN signature 50 66 1.3E-51 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP3_RS00150 f30e0257b31d92982f46323dfb5b1b0e 531 PIRSF PIRSF002869 1 528 1.2E-116 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP3_RS00150 f30e0257b31d92982f46323dfb5b1b0e 531 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 8 524 4.1E-97 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ L21SP3_RS07330 fc33ca2f94276c84564addb8c36b54cf 172 SUPERFAMILY SSF54364 7 82 1.31E-24 T 09-03-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 L21SP3_RS07330 fc33ca2f94276c84564addb8c36b54cf 172 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 172 26.708 T 09-03-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 L21SP3_RS07330 fc33ca2f94276c84564addb8c36b54cf 172 Gene3D G3DSA:3.10.20.80 5 82 1.3E-30 T 09-03-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 L21SP3_RS07330 fc33ca2f94276c84564addb8c36b54cf 172 SUPERFAMILY SSF55200 86 171 1.44E-30 T 09-03-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 L21SP3_RS07330 fc33ca2f94276c84564addb8c36b54cf 172 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 87 171 1.7E-35 T 09-03-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 L21SP3_RS07330 fc33ca2f94276c84564addb8c36b54cf 172 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 9 171 4.9E-59 T 09-03-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 L21SP3_RS07330 fc33ca2f94276c84564addb8c36b54cf 172 Gene3D G3DSA:3.30.110.10 83 171 3.8E-35 T 09-03-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 L21SP3_RS07330 fc33ca2f94276c84564addb8c36b54cf 172 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 9 79 4.1E-26 T 09-03-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 L21SP3_RS00660 7d960f4ce096faf61e947c1cfdcb7efe 255 Gene3D G3DSA:1.10.1520.10 6 149 5.9E-43 T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 L21SP3_RS00660 7d960f4ce096faf61e947c1cfdcb7efe 255 SMART SM00535 20 150 1.6E-42 T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 L21SP3_RS00660 7d960f4ce096faf61e947c1cfdcb7efe 255 SUPERFAMILY SSF54768 111 236 3.14E-24 T 09-03-2017 L21SP3_RS00660 7d960f4ce096faf61e947c1cfdcb7efe 255 Pfam PF00035 Double-stranded RNA binding motif 157 223 8.3E-19 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain L21SP3_RS00660 7d960f4ce096faf61e947c1cfdcb7efe 255 SUPERFAMILY SSF69065 5 145 7.67E-42 T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 L21SP3_RS00660 7d960f4ce096faf61e947c1cfdcb7efe 255 Gene3D G3DSA:3.30.160.20 156 223 6.7E-23 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain L21SP3_RS00660 7d960f4ce096faf61e947c1cfdcb7efe 255 Pfam PF14622 Ribonuclease-III-like 18 140 2.0E-27 T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 L21SP3_RS00660 7d960f4ce096faf61e947c1cfdcb7efe 255 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 220 27.968 T 09-03-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 L21SP3_RS00660 7d960f4ce096faf61e947c1cfdcb7efe 255 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 8 223 1.1E-69 T 09-03-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 L21SP3_RS00660 7d960f4ce096faf61e947c1cfdcb7efe 255 SMART SM00358 157 224 2.4E-18 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain L21SP3_RS02210 c7b1a264e68962fb1c4fc10cc00af056 620 Pfam PF00474 Sodium:solute symporter family 37 308 1.6E-36 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS02210 c7b1a264e68962fb1c4fc10cc00af056 620 Pfam PF00474 Sodium:solute symporter family 416 543 7.5E-13 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS09350 e6b6e822df3e7ed496e37fb13136427e 472 SUPERFAMILY SSF53649 31 465 5.96E-124 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09350 e6b6e822df3e7ed496e37fb13136427e 472 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 19 5.5E-4 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal L21SP3_RS09350 e6b6e822df3e7ed496e37fb13136427e 472 Pfam PF16347 Domain of unknown function (DUF4976) 373 465 2.3E-11 T 09-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 L21SP3_RS09350 e6b6e822df3e7ed496e37fb13136427e 472 Gene3D G3DSA:3.40.720.10 29 385 2.8E-103 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS09350 e6b6e822df3e7ed496e37fb13136427e 472 Gene3D G3DSA:3.30.1120.10 390 469 1.8E-21 T 09-03-2017 L21SP3_RS09350 e6b6e822df3e7ed496e37fb13136427e 472 Pfam PF00884 Sulfatase 31 363 1.0E-66 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS05645 b4e9e5ab0bd7a012d7653e0c02fe3ee9 67 Gene3D G3DSA:3.10.20.30 1 67 9.1E-20 T 09-03-2017 IPR012675 Beta-grasp domain L21SP3_RS05645 b4e9e5ab0bd7a012d7653e0c02fe3ee9 67 SUPERFAMILY SSF54285 1 66 6.21E-14 T 09-03-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp L21SP3_RS05645 b4e9e5ab0bd7a012d7653e0c02fe3ee9 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 1 67 1.7E-17 T 09-03-2017 IPR010035 ThiS, thiamine-biosynthesis L21SP3_RS05645 b4e9e5ab0bd7a012d7653e0c02fe3ee9 67 Pfam PF02597 ThiS family 2 67 1.7E-12 T 09-03-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 L21SP3_RS08315 591f12062c4fefb18ddadb058ac3b0a4 348 SUPERFAMILY SSF56672 33 291 4.28E-32 T 09-03-2017 L21SP3_RS08315 591f12062c4fefb18ddadb058ac3b0a4 348 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 71 273 1.4E-20 T 09-03-2017 IPR000477 Reverse transcriptase domain L21SP3_RS00255 f87062f857e4b1cf05c7a78eacf74444 362 SMART SM01329 5 355 3.5E-142 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 L21SP3_RS00255 f87062f857e4b1cf05c7a78eacf74444 362 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 250 269 - T 09-03-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 L21SP3_RS00255 f87062f857e4b1cf05c7a78eacf74444 362 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 355 1.1E-88 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 L21SP3_RS00255 f87062f857e4b1cf05c7a78eacf74444 362 Gene3D G3DSA:3.40.718.10 2 358 2.7E-104 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 L21SP3_RS00255 f87062f857e4b1cf05c7a78eacf74444 362 SUPERFAMILY SSF53659 2 357 9.26E-104 T 09-03-2017 L21SP3_RS07665 2bfa65e3e08cce0805d88893b037a28c 53 SUPERFAMILY SSF57802 1 52 1.4E-23 T 09-03-2017 L21SP3_RS07665 2bfa65e3e08cce0805d88893b037a28c 53 PRINTS PR00163 Rubredoxin signature 3 19 7.6E-14 T 09-03-2017 IPR024935 Rubredoxin domain GO:0005506 L21SP3_RS07665 2bfa65e3e08cce0805d88893b037a28c 53 PRINTS PR00163 Rubredoxin signature 33 49 7.6E-14 T 09-03-2017 IPR024935 Rubredoxin domain GO:0005506 L21SP3_RS07665 2bfa65e3e08cce0805d88893b037a28c 53 Pfam PF00301 Rubredoxin 3 49 4.0E-26 T 09-03-2017 IPR024935 Rubredoxin domain GO:0005506 L21SP3_RS07665 2bfa65e3e08cce0805d88893b037a28c 53 Gene3D G3DSA:2.20.28.10 1 53 8.9E-29 T 09-03-2017 IPR004039 Rubredoxin-type fold L21SP3_RS07665 2bfa65e3e08cce0805d88893b037a28c 53 PIRSF PIRSF000071 1 53 2.7E-29 T 09-03-2017 IPR024922 Rubredoxin GO:0005506|GO:0009055 L21SP3_RS07665 2bfa65e3e08cce0805d88893b037a28c 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 09-03-2017 IPR018527 Rubredoxin, iron-binding site GO:0046872 L21SP3_RS10050 fedf09d4a977b77c7e8662b528085e34 109 SMART SM00938 4 102 3.7E-23 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP3_RS10050 fedf09d4a977b77c7e8662b528085e34 109 PRINTS PR00340 P-II protein signature 80 100 3.4E-13 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP3_RS10050 fedf09d4a977b77c7e8662b528085e34 109 PRINTS PR00340 P-II protein signature 49 72 3.4E-13 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP3_RS10050 fedf09d4a977b77c7e8662b528085e34 109 PRINTS PR00340 P-II protein signature 2 17 3.4E-13 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP3_RS10050 fedf09d4a977b77c7e8662b528085e34 109 SUPERFAMILY SSF54913 1 109 4.77E-27 T 09-03-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta L21SP3_RS10050 fedf09d4a977b77c7e8662b528085e34 109 Gene3D G3DSA:3.30.70.120 1 109 1.2E-28 T 09-03-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal L21SP3_RS10050 fedf09d4a977b77c7e8662b528085e34 109 Pfam PF00543 Nitrogen regulatory protein P-II 4 101 1.5E-19 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 PRINTS PR00934 X-His dipeptidase (M25) signature 75 94 3.1E-57 T 09-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 PRINTS PR00934 X-His dipeptidase (M25) signature 154 172 3.1E-57 T 09-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 PRINTS PR00934 X-His dipeptidase (M25) signature 130 147 3.1E-57 T 09-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 PRINTS PR00934 X-His dipeptidase (M25) signature 96 114 3.1E-57 T 09-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 PRINTS PR00934 X-His dipeptidase (M25) signature 200 217 3.1E-57 T 09-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 PRINTS PR00934 X-His dipeptidase (M25) signature 442 464 3.1E-57 T 09-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 PRINTS PR00934 X-His dipeptidase (M25) signature 245 264 3.1E-57 T 09-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 PRINTS PR00934 X-His dipeptidase (M25) signature 420 436 3.1E-57 T 09-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 Pfam PF01546 Peptidase family M20/M25/M40 68 473 1.1E-15 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 SUPERFAMILY SSF53187 389 474 4.98E-51 T 09-03-2017 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 SUPERFAMILY SSF53187 8 176 4.98E-51 T 09-03-2017 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 PIRSF PIRSF016599 1 477 9.3E-144 T 09-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 Gene3D G3DSA:3.40.630.10 3 175 2.9E-79 T 09-03-2017 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 Gene3D G3DSA:3.40.630.10 389 474 2.9E-79 T 09-03-2017 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 7 474 6.9E-137 T 09-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 L21SP3_RS09400 96c024a8d323ecc7dc34c4c545f1f40c 480 Gene3D G3DSA:3.30.70.360 239 302 5.5E-5 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain L21SP3_RS06735 3890716220cafa68bec999a5f4631342 281 SUPERFAMILY SSF89392 234 268 2.16E-7 T 09-03-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX L21SP3_RS06735 3890716220cafa68bec999a5f4631342 281 SUPERFAMILY SSF89392 120 202 2.16E-7 T 09-03-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX L21SP3_RS06735 3890716220cafa68bec999a5f4631342 281 Pfam PF17131 Outer membrane lipoprotein-sorting protein 95 274 2.4E-57 T 09-03-2017 IPR033399 Putative outer membrane lipoprotein-sorting protein L21SP3_RS06735 3890716220cafa68bec999a5f4631342 281 Gene3D G3DSA:2.50.20.10 28 274 2.2E-60 T 09-03-2017 L21SP3_RS07210 f95cfec40caad0ee425728000b34e30a 373 Pfam PF03781 Sulfatase-modifying factor enzyme 1 170 372 2.1E-26 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS07210 f95cfec40caad0ee425728000b34e30a 373 Gene3D G3DSA:3.90.1580.10 169 373 1.9E-36 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS07210 f95cfec40caad0ee425728000b34e30a 373 SUPERFAMILY SSF56436 239 373 1.58E-40 T 09-03-2017 IPR016187 C-type lectin fold L21SP3_RS07210 f95cfec40caad0ee425728000b34e30a 373 SUPERFAMILY SSF56436 167 191 1.58E-40 T 09-03-2017 IPR016187 C-type lectin fold L21SP3_RS05830 5d4d20df5eea47f372f92815a2fe5ea2 68 SUPERFAMILY SSF143034 2 63 2.75E-17 T 09-03-2017 L21SP3_RS05830 5d4d20df5eea47f372f92815a2fe5ea2 68 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.9E-10 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 L21SP3_RS05830 5d4d20df5eea47f372f92815a2fe5ea2 68 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.9E-10 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 L21SP3_RS05830 5d4d20df5eea47f372f92815a2fe5ea2 68 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.9E-10 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 L21SP3_RS05830 5d4d20df5eea47f372f92815a2fe5ea2 68 Pfam PF01632 Ribosomal protein L35 2 62 7.8E-20 T 09-03-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS05830 5d4d20df5eea47f372f92815a2fe5ea2 68 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 1.1E-18 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 L21SP3_RS05830 5d4d20df5eea47f372f92815a2fe5ea2 68 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 14.123 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06815 cee3d786e6f17b4e7f79fdcfd46a408d 351 PIRSF PIRSF004762 1 323 9.8E-69 T 09-03-2017 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 L21SP3_RS06815 cee3d786e6f17b4e7f79fdcfd46a408d 351 TIGRFAM TIGR03956 rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE 10 340 1.7E-101 T 09-03-2017 IPR024021 [FeFe]-hydrogenase maturation HydE, radical SAM L21SP3_RS06815 cee3d786e6f17b4e7f79fdcfd46a408d 351 SMART SM00876 228 322 2.1E-4 T 09-03-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 L21SP3_RS06815 cee3d786e6f17b4e7f79fdcfd46a408d 351 SMART SM00729 54 257 3.7E-22 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP3_RS06815 cee3d786e6f17b4e7f79fdcfd46a408d 351 Gene3D G3DSA:3.20.20.70 17 322 2.3E-74 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS06815 cee3d786e6f17b4e7f79fdcfd46a408d 351 Pfam PF04055 Radical SAM superfamily 59 212 4.0E-17 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS06815 cee3d786e6f17b4e7f79fdcfd46a408d 351 SUPERFAMILY SSF102114 21 294 4.97E-52 T 09-03-2017 L21SP3_RS04440 3b46d5af1a235bf1b55245c41dab403f 189 SUPERFAMILY SSF160527 118 182 2.88E-5 T 09-03-2017 L21SP3_RS04440 3b46d5af1a235bf1b55245c41dab403f 189 Gene3D G3DSA:1.10.520.20 4 107 3.6E-18 T 09-03-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 L21SP3_RS04440 3b46d5af1a235bf1b55245c41dab403f 189 Pfam PF00213 ATP synthase delta (OSCP) subunit 8 172 1.3E-37 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 L21SP3_RS04440 3b46d5af1a235bf1b55245c41dab403f 189 SUPERFAMILY SSF47928 5 107 7.72E-18 T 09-03-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 L21SP3_RS04440 3b46d5af1a235bf1b55245c41dab403f 189 PRINTS PR00125 ATP synthase delta subunit signature 7 26 2.2E-16 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 L21SP3_RS04440 3b46d5af1a235bf1b55245c41dab403f 189 PRINTS PR00125 ATP synthase delta subunit signature 152 170 2.2E-16 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 L21SP3_RS04440 3b46d5af1a235bf1b55245c41dab403f 189 PRINTS PR00125 ATP synthase delta subunit signature 137 152 2.2E-16 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 L21SP3_RS04440 3b46d5af1a235bf1b55245c41dab403f 189 PRINTS PR00125 ATP synthase delta subunit signature 87 101 2.2E-16 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 L21SP3_RS04440 3b46d5af1a235bf1b55245c41dab403f 189 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 179 15.818 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 L21SP3_RS04440 3b46d5af1a235bf1b55245c41dab403f 189 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 8 173 1.8E-31 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 L21SP3_RS01515 acb20a16a9c8983b0b4032ad9e0bd987 476 Pfam PF00884 Sulfatase 30 341 1.9E-68 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS01515 acb20a16a9c8983b0b4032ad9e0bd987 476 Gene3D G3DSA:3.40.720.10 28 363 8.7E-106 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS01515 acb20a16a9c8983b0b4032ad9e0bd987 476 Gene3D G3DSA:3.30.1120.10 369 458 2.5E-19 T 09-03-2017 L21SP3_RS01515 acb20a16a9c8983b0b4032ad9e0bd987 476 SUPERFAMILY SSF53649 28 454 1.6E-122 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 Gene3D G3DSA:3.30.70.380 577 668 1.6E-24 T 09-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 Gene3D G3DSA:3.30.56.10 1 70 8.5E-21 T 09-03-2017 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 SUPERFAMILY SSF46955 1 76 3.66E-19 T 09-03-2017 IPR009061 Putative DNA-binding domain L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 33 668 5.1E-153 T 09-03-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 SUPERFAMILY SSF46955 291 364 1.01E-16 T 09-03-2017 IPR009061 Putative DNA-binding domain L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 662 31.996 T 09-03-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 Pfam PF03147 Ferredoxin-fold anticodon binding domain 576 668 6.3E-24 T 09-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 Gene3D G3DSA:3.30.930.10 377 563 3.7E-23 T 09-03-2017 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 SMART SM00896 576 668 5.6E-27 T 09-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 Pfam PF03483 B3/4 domain 101 270 1.4E-60 T 09-03-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 SMART SM00873 100 273 2.4E-78 T 09-03-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 Gene3D G3DSA:3.30.56.20 291 364 1.3E-24 T 09-03-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 SUPERFAMILY SSF56037 89 281 1.78E-65 T 09-03-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 SUPERFAMILY SSF55681 356 562 1.14E-19 T 09-03-2017 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 SUPERFAMILY SSF54991 572 668 1.18E-23 T 09-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 Gene3D G3DSA:3.50.40.10 89 282 1.7E-75 T 09-03-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 SMART SM00874 290 360 6.2E-23 T 09-03-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 L21SP3_RS07295 92f6cb7fef7fcbc7cb2ee697455f5a8b 670 Pfam PF03484 tRNA synthetase B5 domain 292 360 2.1E-19 T 09-03-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 L21SP3_RS11035 db642f3d52357444712ac6848caa1414 256 Gene3D G3DSA:3.60.15.10 2 227 3.6E-29 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS11035 db642f3d52357444712ac6848caa1414 256 SMART SM00849 11 180 1.3E-6 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS11035 db642f3d52357444712ac6848caa1414 256 Pfam PF00753 Metallo-beta-lactamase superfamily 11 184 1.7E-20 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS11035 db642f3d52357444712ac6848caa1414 256 SUPERFAMILY SSF56281 3 218 8.65E-36 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS01290 06942bced0294f6addef5cbf9ae78875 369 Pfam PF00155 Aminotransferase class I and II 29 363 9.0E-61 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 L21SP3_RS01290 06942bced0294f6addef5cbf9ae78875 369 Gene3D G3DSA:3.90.1150.10 264 367 2.1E-25 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS01290 06942bced0294f6addef5cbf9ae78875 369 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 223 236 - T 09-03-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 L21SP3_RS01290 06942bced0294f6addef5cbf9ae78875 369 Gene3D G3DSA:3.40.640.10 42 263 4.6E-66 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS01290 06942bced0294f6addef5cbf9ae78875 369 SUPERFAMILY SSF53383 6 368 2.24E-95 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS02865 2f254ff17ef0b25ecb27390f977ba38f 469 Hamap MF_00675 Uronate isomerase [uxaC]. 2 466 48.697 T 09-03-2017 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 L21SP3_RS02865 2f254ff17ef0b25ecb27390f977ba38f 469 Gene3D G3DSA:1.10.2020.10 47 135 4.4E-39 T 09-03-2017 IPR023177 Uronate isomerase, domain 2 GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 L21SP3_RS02865 2f254ff17ef0b25ecb27390f977ba38f 469 Gene3D G3DSA:3.20.20.140 138 465 1.7E-154 T 09-03-2017 L21SP3_RS02865 2f254ff17ef0b25ecb27390f977ba38f 469 Gene3D G3DSA:3.20.20.140 3 44 1.7E-154 T 09-03-2017 L21SP3_RS02865 2f254ff17ef0b25ecb27390f977ba38f 469 SUPERFAMILY SSF51556 3 465 2.27E-180 T 09-03-2017 IPR032466 Metal-dependent hydrolase L21SP3_RS02865 2f254ff17ef0b25ecb27390f977ba38f 469 Pfam PF02614 Glucuronate isomerase 1 464 5.4E-215 T 09-03-2017 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 SUPERFAMILY SSF82693 48 136 8.2E-19 T 09-03-2017 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 Gene3D G3DSA:3.30.70.1320 161 182 9.0E-8 T 09-03-2017 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 Gene3D G3DSA:3.30.70.1320 274 310 9.0E-8 T 09-03-2017 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 SUPERFAMILY SSF82866 299 491 5.62E-40 T 09-03-2017 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 Gene3D G3DSA:3.30.2090.10 185 272 1.9E-13 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 SUPERFAMILY SSF82866 798 1021 8.37E-48 T 09-03-2017 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 Pfam PF00873 AcrB/AcrD/AcrF family 17 1018 1.2E-170 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 1.1E-23 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 1.1E-23 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 PRINTS PR00702 Acriflavin resistance protein family signature 441 464 1.1E-23 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 1.1E-23 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 PRINTS PR00702 Acriflavin resistance protein family signature 46 64 1.1E-23 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 Gene3D G3DSA:3.30.2090.10 712 796 2.2E-9 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 SUPERFAMILY SSF82714 186 270 9.16E-14 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 SUPERFAMILY SSF82693 152 185 2.14E-11 T 09-03-2017 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 SUPERFAMILY SSF82693 272 328 2.14E-11 T 09-03-2017 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 Gene3D G3DSA:1.20.1640.10 311 498 6.5E-46 T 09-03-2017 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 Gene3D G3DSA:3.30.70.1430 49 136 2.5E-19 T 09-03-2017 L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 SUPERFAMILY SSF82714 723 796 1.03E-9 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS08860 af9403b76d6961454e61898ea4873ef2 1036 Gene3D G3DSA:1.10.3850.10 802 1020 2.5E-61 T 09-03-2017 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 Gene3D G3DSA:3.10.290.10 332 401 6.3E-25 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 SMART SM00363 340 402 1.1E-7 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 Pfam PF01479 S4 domain 344 385 1.8E-9 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 57 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 185 207 2.1E-24 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 51 73 2.1E-24 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 218 230 2.1E-24 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 168 183 2.1E-24 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 3 401 45.328 T 09-03-2017 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 SUPERFAMILY SSF55174 304 401 1.7E-22 T 09-03-2017 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 Pfam PF00579 tRNA synthetases class I (W and Y) 35 321 5.4E-69 T 09-03-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 6 401 1.9E-119 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 SUPERFAMILY SSF52374 9 321 1.04E-83 T 09-03-2017 L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 Gene3D G3DSA:3.40.50.620 10 234 7.8E-78 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS00615 30d0e6b29522344653d1abfc0ba1a364 402 Gene3D G3DSA:1.10.240.10 235 331 1.6E-32 T 09-03-2017 L21SP3_RS07715 0bde21c3359a1964dbff7401f8e883e0 383 SUPERFAMILY SSF52540 21 348 2.95E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07715 0bde21c3359a1964dbff7401f8e883e0 383 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 25 332 2.2E-10 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP3_RS07715 0bde21c3359a1964dbff7401f8e883e0 383 Gene3D G3DSA:3.40.50.300 21 347 7.5E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07540 21be286bf0ea30e7fe294e94f82b67c0 420 SUPERFAMILY SSF52402 5 206 6.84E-43 T 09-03-2017 L21SP3_RS07540 21be286bf0ea30e7fe294e94f82b67c0 420 Hamap MF_00005 Argininosuccinate synthase [argG]. 4 401 51.451 T 09-03-2017 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS07540 21be286bf0ea30e7fe294e94f82b67c0 420 Gene3D G3DSA:3.90.1260.10 178 402 4.8E-94 T 09-03-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS07540 21be286bf0ea30e7fe294e94f82b67c0 420 SUPERFAMILY SSF69864 176 402 3.53E-91 T 09-03-2017 L21SP3_RS07540 21be286bf0ea30e7fe294e94f82b67c0 420 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 10 18 - T 09-03-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS07540 21be286bf0ea30e7fe294e94f82b67c0 420 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 118 129 - T 09-03-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS07540 21be286bf0ea30e7fe294e94f82b67c0 420 Gene3D G3DSA:3.40.50.620 5 175 9.2E-61 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS07540 21be286bf0ea30e7fe294e94f82b67c0 420 TIGRFAM TIGR00032 argG: argininosuccinate synthase 6 397 1.9E-149 T 09-03-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS07540 21be286bf0ea30e7fe294e94f82b67c0 420 Pfam PF00764 Arginosuccinate synthase 8 395 5.3E-159 T 09-03-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS03060 298e270d505c25565ff628b73aa7f4e0 180 SUPERFAMILY SSF52540 3 180 6.3E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03060 298e270d505c25565ff628b73aa7f4e0 180 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 4 180 2.7E-51 T 09-03-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 L21SP3_RS03060 298e270d505c25565ff628b73aa7f4e0 180 PIRSF PIRSF015617 1 180 4.5E-51 T 09-03-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 L21SP3_RS03060 298e270d505c25565ff628b73aa7f4e0 180 Gene3D G3DSA:3.40.50.300 3 180 3.2E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01035 4760276c17ac03c75dc6a11831494ca1 232 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 17 213 3.5E-35 T 09-03-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 L21SP3_RS01035 4760276c17ac03c75dc6a11831494ca1 232 SUPERFAMILY SSF51366 16 215 2.67E-44 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP3_RS01035 4760276c17ac03c75dc6a11831494ca1 232 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 15 218 29.567 T 09-03-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 L21SP3_RS01035 4760276c17ac03c75dc6a11831494ca1 232 Gene3D G3DSA:3.20.20.70 16 216 1.8E-49 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS04035 51a1cd84b818768bb38def4cbb796b71 245 Pfam PF02591 C4-type zinc ribbon domain 206 237 1.3E-12 T 09-03-2017 IPR003743 C4-type zinc ribbon domain L21SP3_RS05550 923c8b7ff9a9b3a17400e80e38cc5a82 560 PRINTS PR00095 Anthranilate synthase component I signature 194 207 1.0E-9 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 L21SP3_RS05550 923c8b7ff9a9b3a17400e80e38cc5a82 560 PRINTS PR00095 Anthranilate synthase component I signature 299 313 1.0E-9 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 L21SP3_RS05550 923c8b7ff9a9b3a17400e80e38cc5a82 560 PRINTS PR00095 Anthranilate synthase component I signature 208 221 1.0E-9 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 L21SP3_RS05550 923c8b7ff9a9b3a17400e80e38cc5a82 560 PRINTS PR00095 Anthranilate synthase component I signature 285 299 1.0E-9 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 L21SP3_RS05550 923c8b7ff9a9b3a17400e80e38cc5a82 560 Gene3D G3DSA:3.60.120.10 94 346 2.1E-92 T 09-03-2017 IPR005801 ADC synthase GO:0009058 L21SP3_RS05550 923c8b7ff9a9b3a17400e80e38cc5a82 560 SUPERFAMILY SSF56322 28 346 7.46E-87 T 09-03-2017 IPR005801 ADC synthase GO:0009058 L21SP3_RS05550 923c8b7ff9a9b3a17400e80e38cc5a82 560 SUPERFAMILY SSF56752 352 540 1.44E-30 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 L21SP3_RS05550 923c8b7ff9a9b3a17400e80e38cc5a82 560 Pfam PF01063 Amino-transferase class IV 354 541 2.4E-23 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 L21SP3_RS05550 923c8b7ff9a9b3a17400e80e38cc5a82 560 Pfam PF00425 chorismate binding enzyme 100 342 6.3E-73 T 09-03-2017 IPR015890 Chorismate-utilising enzyme, C-terminal L21SP3_RS05550 923c8b7ff9a9b3a17400e80e38cc5a82 560 Gene3D G3DSA:3.20.10.10 442 539 1.9E-23 T 09-03-2017 L21SP3_RS05210 f8928a94d9862ea5a565de5a3f43929e 286 Pfam PF01063 Amino-transferase class IV 32 251 3.0E-37 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 L21SP3_RS05210 f8928a94d9862ea5a565de5a3f43929e 286 Gene3D G3DSA:3.20.10.10 124 280 6.0E-36 T 09-03-2017 L21SP3_RS05210 f8928a94d9862ea5a565de5a3f43929e 286 Gene3D G3DSA:3.30.470.10 6 117 3.6E-29 T 09-03-2017 L21SP3_RS05210 f8928a94d9862ea5a565de5a3f43929e 286 SUPERFAMILY SSF56752 8 280 3.14E-64 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 L21SP3_RS04660 3790a945cae493f1876cc4729429d437 478 SUPERFAMILY SSF158544 150 225 6.02E-12 T 09-03-2017 L21SP3_RS04660 3790a945cae493f1876cc4729429d437 478 Gene3D G3DSA:1.10.40.60 175 225 8.0E-13 T 09-03-2017 L21SP3_RS04660 3790a945cae493f1876cc4729429d437 478 Pfam PF03934 Type II secretion system (T2SS), protein K 85 225 3.0E-11 T 09-03-2017 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 L21SP3_RS04660 3790a945cae493f1876cc4729429d437 478 Gene3D G3DSA:1.10.150.280 133 174 3.3E-4 T 09-03-2017 L21SP3_RS10000 dcee18700a21a08e23d06062e0a4b11c 810 ProSitePatterns PS00018 EF-hand calcium-binding domain. 781 793 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS10000 dcee18700a21a08e23d06062e0a4b11c 810 SUPERFAMILY SSF49899 549 767 2.16E-22 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10000 dcee18700a21a08e23d06062e0a4b11c 810 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 622 763 8.5E-13 T 09-03-2017 L21SP3_RS10000 dcee18700a21a08e23d06062e0a4b11c 810 Gene3D G3DSA:2.60.120.200 546 764 9.9E-19 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10955 00285dd4f5c95a85b651a795dbbdab78 647 SUPERFAMILY SSF53649 33 365 8.0E-82 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS10955 00285dd4f5c95a85b651a795dbbdab78 647 SUPERFAMILY SSF53649 403 448 8.0E-82 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS10955 00285dd4f5c95a85b651a795dbbdab78 647 Gene3D G3DSA:3.30.1120.10 351 367 4.5E-14 T 09-03-2017 L21SP3_RS10955 00285dd4f5c95a85b651a795dbbdab78 647 Gene3D G3DSA:3.30.1120.10 405 450 4.5E-14 T 09-03-2017 L21SP3_RS10955 00285dd4f5c95a85b651a795dbbdab78 647 Gene3D G3DSA:3.40.720.10 128 350 8.2E-32 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS10955 00285dd4f5c95a85b651a795dbbdab78 647 Gene3D G3DSA:3.40.720.10 31 127 5.2E-27 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS10955 00285dd4f5c95a85b651a795dbbdab78 647 Pfam PF00884 Sulfatase 127 310 1.4E-19 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS10955 00285dd4f5c95a85b651a795dbbdab78 647 Pfam PF00884 Sulfatase 33 123 1.3E-17 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS10955 00285dd4f5c95a85b651a795dbbdab78 647 Gene3D G3DSA:1.25.10.10 496 572 4.3E-4 T 09-03-2017 IPR011989 Armadillo-like helical L21SP3_RS04400 a880b3db4def98b8ae1d005dcf8fb588 182 Gene3D G3DSA:3.40.50.2300 42 167 4.8E-33 T 09-03-2017 L21SP3_RS04400 a880b3db4def98b8ae1d005dcf8fb588 182 SUPERFAMILY SSF52172 42 171 9.68E-31 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS04400 a880b3db4def98b8ae1d005dcf8fb588 182 SMART SM00448 42 164 4.8E-26 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS04400 a880b3db4def98b8ae1d005dcf8fb588 182 Pfam PF00072 Response regulator receiver domain 44 159 6.4E-20 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 13 474 1.2E-142 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 SUPERFAMILY SSF52283 398 475 2.95E-109 T 09-03-2017 L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 SUPERFAMILY SSF52283 11 150 2.95E-109 T 09-03-2017 L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 SUPERFAMILY SSF52283 187 234 2.95E-109 T 09-03-2017 L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 257 273 - T 09-03-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 9 467 46.12 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 SMART SM00997 235 397 3.7E-102 T 09-03-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 PIRSF PIRSF001109 1 475 8.5E-184 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 14 467 1.4E-176 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 SMART SM00996 13 474 3.4E-297 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 SUPERFAMILY SSF51735 235 397 1.18E-74 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 Gene3D G3DSA:3.40.50.720 237 396 4.7E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 235 397 3.3E-75 T 09-03-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 Gene3D G3DSA:3.40.50.1480 398 475 2.9E-139 T 09-03-2017 L21SP3_RS04930 4207249102f09a07c7c7434d0eb38f94 475 Gene3D G3DSA:3.40.50.1480 12 236 2.9E-139 T 09-03-2017 L21SP3_RS03995 e1bc06573f9b72115f9c9e97aba1c48e 509 SUPERFAMILY SSF53756 36 504 1.19E-65 T 09-03-2017 L21SP3_RS03995 e1bc06573f9b72115f9c9e97aba1c48e 509 Pfam PF08323 Starch synthase catalytic domain 14 241 2.0E-36 T 09-03-2017 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 L21SP3_RS03995 e1bc06573f9b72115f9c9e97aba1c48e 509 Gene3D G3DSA:3.40.50.2000 272 479 9.6E-48 T 09-03-2017 L21SP3_RS03995 e1bc06573f9b72115f9c9e97aba1c48e 509 Pfam PF00534 Glycosyl transferases group 1 310 473 1.1E-10 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS06230 2209bbe52dac193c6b8481569f404061 722 Pfam PF07679 Immunoglobulin I-set domain 361 456 2.5E-9 T 09-03-2017 IPR013098 Immunoglobulin I-set L21SP3_RS06230 2209bbe52dac193c6b8481569f404061 722 SUPERFAMILY SSF49899 462 674 8.71E-22 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS06230 2209bbe52dac193c6b8481569f404061 722 SUPERFAMILY SSF48726 361 460 9.03E-13 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS06230 2209bbe52dac193c6b8481569f404061 722 Gene3D G3DSA:2.60.40.10 361 460 2.7E-13 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS06230 2209bbe52dac193c6b8481569f404061 722 SMART SM00409 367 460 2.3E-6 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS06230 2209bbe52dac193c6b8481569f404061 722 Gene3D G3DSA:2.60.120.200 52 194 6.9E-4 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS06230 2209bbe52dac193c6b8481569f404061 722 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 525 670 9.5E-18 T 09-03-2017 L21SP3_RS06230 2209bbe52dac193c6b8481569f404061 722 Gene3D G3DSA:2.60.120.200 461 677 2.4E-21 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS01320 95b8903a1ab4ba9c304c1f8c3857f007 161 SUPERFAMILY SSF54637 4 127 1.57E-25 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS01320 95b8903a1ab4ba9c304c1f8c3857f007 161 Gene3D G3DSA:3.10.129.10 4 122 3.9E-26 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS01320 95b8903a1ab4ba9c304c1f8c3857f007 161 Pfam PF07977 FabA-like domain 6 96 1.4E-14 T 09-03-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 L21SP3_RS03570 c057f31d9fb4992b8560cf9209ff67c8 295 SUPERFAMILY SSF82282 5 294 4.58E-83 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 L21SP3_RS03570 c057f31d9fb4992b8560cf9209ff67c8 295 Pfam PF02574 Homocysteine S-methyltransferase 15 291 1.0E-58 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 L21SP3_RS03570 c057f31d9fb4992b8560cf9209ff67c8 295 PIRSF PIRSF037505 3 294 1.9E-10 T 09-03-2017 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 L21SP3_RS03570 c057f31d9fb4992b8560cf9209ff67c8 295 Gene3D G3DSA:3.20.20.330 2 294 6.4E-87 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 L21SP3_RS00135 c1c9ec88db1c7983c1912719e6b1d59c 296 SUPERFAMILY SSF48452 28 99 3.37E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00135 c1c9ec88db1c7983c1912719e6b1d59c 296 Pfam PF14559 Tetratricopeptide repeat 33 91 2.5E-7 T 09-03-2017 L21SP3_RS00135 c1c9ec88db1c7983c1912719e6b1d59c 296 Gene3D G3DSA:1.25.40.10 29 90 5.2E-8 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS01020 5549ebcb9147fee7300f2de3ab395f77 416 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 413 1.1E-176 T 09-03-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 L21SP3_RS01020 5549ebcb9147fee7300f2de3ab395f77 416 SUPERFAMILY SSF53901 216 415 2.1E-65 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01020 5549ebcb9147fee7300f2de3ab395f77 416 Gene3D G3DSA:3.40.47.10 265 415 1.0E-54 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01020 5549ebcb9147fee7300f2de3ab395f77 416 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 248 1.9E-57 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal L21SP3_RS01020 5549ebcb9147fee7300f2de3ab395f77 416 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site L21SP3_RS01020 5549ebcb9147fee7300f2de3ab395f77 416 SMART SM00825 Beta-ketoacyl synthase 6 415 4.5E-13 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain L21SP3_RS01020 5549ebcb9147fee7300f2de3ab395f77 416 SUPERFAMILY SSF53901 4 253 8.32E-72 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01020 5549ebcb9147fee7300f2de3ab395f77 416 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 370 2.3E-34 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal L21SP3_RS01020 5549ebcb9147fee7300f2de3ab395f77 416 PIRSF PIRSF000447 1 416 4.4E-167 T 09-03-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 L21SP3_RS01020 5549ebcb9147fee7300f2de3ab395f77 416 Gene3D G3DSA:3.40.47.10 3 258 4.0E-74 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS00540 9386a32066a1af78884c402a59faf1a7 150 Pfam PF08308 PEGA domain 32 85 1.6E-11 T 09-03-2017 IPR013229 PEGA L21SP3_RS06160 0c31a5640b68adc20f80f726a0b94e3b 129 Pfam PF00238 Ribosomal protein L14p/L23e 2 129 7.3E-46 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06160 0c31a5640b68adc20f80f726a0b94e3b 129 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 129 5.1E-45 T 09-03-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 L21SP3_RS06160 0c31a5640b68adc20f80f726a0b94e3b 129 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 129 24.115 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06160 0c31a5640b68adc20f80f726a0b94e3b 129 SMART SM01374 1 129 4.9E-68 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06160 0c31a5640b68adc20f80f726a0b94e3b 129 Gene3D G3DSA:2.40.150.20 2 129 4.0E-46 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06160 0c31a5640b68adc20f80f726a0b94e3b 129 SUPERFAMILY SSF50193 2 129 1.96E-44 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 L21SP3_RS04390 49743bb6327a68cef76889f8832ebd4c 487 Pfam PF13432 Tetratricopeptide repeat 410 458 6.5E-4 T 09-03-2017 L21SP3_RS04390 49743bb6327a68cef76889f8832ebd4c 487 Gene3D G3DSA:1.25.40.10 352 415 4.2E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS04390 49743bb6327a68cef76889f8832ebd4c 487 Gene3D G3DSA:1.25.40.10 165 243 2.6E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS04390 49743bb6327a68cef76889f8832ebd4c 487 Gene3D G3DSA:1.25.40.10 34 72 2.6E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS04390 49743bb6327a68cef76889f8832ebd4c 487 SUPERFAMILY SSF48452 354 476 1.41E-16 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS04390 49743bb6327a68cef76889f8832ebd4c 487 SMART SM00028 162 195 400.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS04390 49743bb6327a68cef76889f8832ebd4c 487 SMART SM00028 439 472 98.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS04390 49743bb6327a68cef76889f8832ebd4c 487 SMART SM00028 36 69 16.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS04390 49743bb6327a68cef76889f8832ebd4c 487 SMART SM00028 366 399 200.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS04390 49743bb6327a68cef76889f8832ebd4c 487 SMART SM00028 400 433 0.71 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS04390 49743bb6327a68cef76889f8832ebd4c 487 Gene3D G3DSA:1.25.40.10 416 478 2.1E-8 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS07325 a12d3e4cd880bc82e2c9f2e66547f281 630 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS07325 a12d3e4cd880bc82e2c9f2e66547f281 630 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS07325 a12d3e4cd880bc82e2c9f2e66547f281 630 SMART SM00382 28 228 7.7E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS07325 a12d3e4cd880bc82e2c9f2e66547f281 630 SMART SM00382 343 513 1.3E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS07325 a12d3e4cd880bc82e2c9f2e66547f281 630 Pfam PF00005 ABC transporter 21 183 4.9E-21 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS07325 a12d3e4cd880bc82e2c9f2e66547f281 630 Pfam PF00005 ABC transporter 336 468 3.1E-22 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS07325 a12d3e4cd880bc82e2c9f2e66547f281 630 SUPERFAMILY SSF52540 124 232 9.91E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07325 a12d3e4cd880bc82e2c9f2e66547f281 630 SUPERFAMILY SSF52540 3 94 9.91E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07325 a12d3e4cd880bc82e2c9f2e66547f281 630 Pfam PF12848 ABC transporter 222 295 6.7E-10 T 09-03-2017 IPR032781 ABC-transporter extension domain L21SP3_RS07325 a12d3e4cd880bc82e2c9f2e66547f281 630 SUPERFAMILY SSF52540 319 515 1.0E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07325 a12d3e4cd880bc82e2c9f2e66547f281 630 Pfam PF16326 ABC transporter C-terminal domain 555 623 2.4E-20 T 09-03-2017 IPR032524 ABC transporter Uup, C-terminal GO:0003677 L21SP3_RS07325 a12d3e4cd880bc82e2c9f2e66547f281 630 Gene3D G3DSA:3.40.50.300 320 554 5.4E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07325 a12d3e4cd880bc82e2c9f2e66547f281 630 Gene3D G3DSA:3.40.50.300 6 279 1.8E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06715 c29408c12c28b76cc9906eb54819c894 508 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 212 227 4.1E-7 T 09-03-2017 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 L21SP3_RS06715 c29408c12c28b76cc9906eb54819c894 508 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 321 334 4.1E-7 T 09-03-2017 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 L21SP3_RS06715 c29408c12c28b76cc9906eb54819c894 508 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 345 357 4.1E-7 T 09-03-2017 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 L21SP3_RS06715 c29408c12c28b76cc9906eb54819c894 508 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 293 307 4.1E-7 T 09-03-2017 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 L21SP3_RS06715 c29408c12c28b76cc9906eb54819c894 508 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 407 502 3.7E-29 T 09-03-2017 IPR025158 Mg chelatase-related protein, C-terminal domain L21SP3_RS06715 c29408c12c28b76cc9906eb54819c894 508 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 142 6.7E-43 T 09-03-2017 L21SP3_RS06715 c29408c12c28b76cc9906eb54819c894 508 SUPERFAMILY SSF54211 7 168 6.45E-36 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS06715 c29408c12c28b76cc9906eb54819c894 508 Gene3D G3DSA:3.30.230.10 5 167 8.1E-34 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP3_RS06715 c29408c12c28b76cc9906eb54819c894 508 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 9 502 1.0E-187 T 09-03-2017 IPR004482 Mg chelatase-related protein L21SP3_RS06715 c29408c12c28b76cc9906eb54819c894 508 SUPERFAMILY SSF52540 191 505 3.63E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06715 c29408c12c28b76cc9906eb54819c894 508 Pfam PF01078 Magnesium chelatase, subunit ChlI 193 398 5.5E-95 T 09-03-2017 IPR000523 Magnesium chelatase ChlI domain L21SP3_RS06715 c29408c12c28b76cc9906eb54819c894 508 SMART SM00382 213 396 3.4E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS06715 c29408c12c28b76cc9906eb54819c894 508 Gene3D G3DSA:3.40.50.300 192 393 5.5E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04900 f9bce655683d8836d13b05c7d1526f79 325 SUPERFAMILY SSF52313 1 220 1.03E-76 T 09-03-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain L21SP3_RS04900 f9bce655683d8836d13b05c7d1526f79 325 Gene3D G3DSA:1.10.287.610 92 144 1.5E-17 T 09-03-2017 L21SP3_RS04900 f9bce655683d8836d13b05c7d1526f79 325 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 1 217 33.366 T 09-03-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 L21SP3_RS04900 f9bce655683d8836d13b05c7d1526f79 325 Gene3D G3DSA:3.40.50.10490 15 91 2.6E-56 T 09-03-2017 L21SP3_RS04900 f9bce655683d8836d13b05c7d1526f79 325 Gene3D G3DSA:3.40.50.10490 150 236 2.6E-56 T 09-03-2017 L21SP3_RS04900 f9bce655683d8836d13b05c7d1526f79 325 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 150 174 - T 09-03-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 L21SP3_RS04900 f9bce655683d8836d13b05c7d1526f79 325 PRINTS PR00395 Ribosomal protein S2 signature 150 167 6.4E-24 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04900 f9bce655683d8836d13b05c7d1526f79 325 PRINTS PR00395 Ribosomal protein S2 signature 79 96 6.4E-24 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04900 f9bce655683d8836d13b05c7d1526f79 325 PRINTS PR00395 Ribosomal protein S2 signature 29 38 6.4E-24 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04900 f9bce655683d8836d13b05c7d1526f79 325 PRINTS PR00395 Ribosomal protein S2 signature 188 202 6.4E-24 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04900 f9bce655683d8836d13b05c7d1526f79 325 PRINTS PR00395 Ribosomal protein S2 signature 167 178 6.4E-24 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04900 f9bce655683d8836d13b05c7d1526f79 325 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 1 218 1.2E-82 T 09-03-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 L21SP3_RS04900 f9bce655683d8836d13b05c7d1526f79 325 Pfam PF00318 Ribosomal protein S2 1 216 2.5E-80 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 SUPERFAMILY SSF50156 270 343 7.62E-16 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 Pfam PF13180 PDZ domain 267 338 2.1E-12 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 Pfam PF13180 PDZ domain 379 435 1.2E-8 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 Gene3D G3DSA:2.30.42.10 266 342 7.8E-16 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 Gene3D G3DSA:2.30.42.10 360 435 4.7E-16 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 Pfam PF13365 Trypsin-like peptidase domain 79 218 2.3E-34 T 09-03-2017 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 Gene3D G3DSA:2.40.10.10 72 152 1.4E-28 T 09-03-2017 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 PRINTS PR00834 HtrA/DegQ protease family signature 109 129 4.1E-45 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 PRINTS PR00834 HtrA/DegQ protease family signature 287 299 4.1E-45 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 PRINTS PR00834 HtrA/DegQ protease family signature 189 206 4.1E-45 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 PRINTS PR00834 HtrA/DegQ protease family signature 211 228 4.1E-45 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 PRINTS PR00834 HtrA/DegQ protease family signature 152 176 4.1E-45 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 PRINTS PR00834 HtrA/DegQ protease family signature 88 100 4.1E-45 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 SUPERFAMILY SSF50494 28 242 3.38E-54 T 09-03-2017 IPR009003 Peptidase S1, PA clan L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 Gene3D G3DSA:2.40.10.10 153 242 1.2E-34 T 09-03-2017 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 SUPERFAMILY SSF50156 381 441 9.86E-13 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 SMART SM00228 254 329 2.5E-7 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS09665 c1bf940040378bb0ef289a550e305a2b 466 SMART SM00228 369 437 1.2E-8 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS02730 bddb014fdc04b785d18c9551b2742f05 150 Pfam PF00583 Acetyltransferase (GNAT) family 45 117 1.5E-11 T 09-03-2017 IPR000182 GNAT domain GO:0008080 L21SP3_RS02730 bddb014fdc04b785d18c9551b2742f05 150 Gene3D G3DSA:3.40.630.30 1 137 1.1E-28 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS02730 bddb014fdc04b785d18c9551b2742f05 150 SUPERFAMILY SSF55729 1 125 1.89E-23 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS01280 25ab1f58fb4d74a07aeb165af2c3982d 374 Pfam PF13394 4Fe-4S single cluster domain 14 102 5.3E-5 T 09-03-2017 L21SP3_RS01280 25ab1f58fb4d74a07aeb165af2c3982d 374 Gene3D G3DSA:3.20.20.70 6 336 3.0E-50 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS01280 25ab1f58fb4d74a07aeb165af2c3982d 374 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 171 372 7.0E-6 T 09-03-2017 L21SP3_RS01280 25ab1f58fb4d74a07aeb165af2c3982d 374 TIGRFAM TIGR03942 sulfatase_rSAM: anaerobic sulfatase maturase 6 364 4.2E-129 T 09-03-2017 IPR023867 Anaerobic sulphatase maturase, radical SAM GO:0016491 L21SP3_RS01280 25ab1f58fb4d74a07aeb165af2c3982d 374 Pfam PF13186 Iron-sulfur cluster-binding domain 259 318 1.2E-6 T 09-03-2017 IPR023885 4Fe4S-binding SPASM domain L21SP3_RS01280 25ab1f58fb4d74a07aeb165af2c3982d 374 Pfam PF04055 Radical SAM superfamily 12 179 1.6E-15 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS01280 25ab1f58fb4d74a07aeb165af2c3982d 374 SUPERFAMILY SSF102114 14 328 3.66E-44 T 09-03-2017 L21SP3_RS01280 25ab1f58fb4d74a07aeb165af2c3982d 374 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 261 346 4.4E-16 T 09-03-2017 IPR023885 4Fe4S-binding SPASM domain L21SP3_RS04535 aa5cb5763e1f2de4aafa6da27bc9d874 511 Gene3D G3DSA:3.40.720.10 15 378 9.0E-98 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS04535 aa5cb5763e1f2de4aafa6da27bc9d874 511 SUPERFAMILY SSF53649 16 461 4.19E-113 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS04535 aa5cb5763e1f2de4aafa6da27bc9d874 511 Pfam PF00884 Sulfatase 17 359 1.7E-54 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS04535 aa5cb5763e1f2de4aafa6da27bc9d874 511 Pfam PF16347 Domain of unknown function (DUF4976) 362 462 1.6E-15 T 09-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 L21SP3_RS04535 aa5cb5763e1f2de4aafa6da27bc9d874 511 Gene3D G3DSA:3.30.1120.10 408 468 1.7E-11 T 09-03-2017 L21SP3_RS07995 5c2aa5f5ddac47cc3561bac6fa014534 316 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 311 1.5E-101 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 L21SP3_RS07995 5c2aa5f5ddac47cc3561bac6fa014534 316 PIRSF PIRSF001359 1 312 5.7E-103 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 L21SP3_RS07995 5c2aa5f5ddac47cc3561bac6fa014534 316 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 312 5.3E-95 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 L21SP3_RS07995 5c2aa5f5ddac47cc3561bac6fa014534 316 SUPERFAMILY SSF51569 3 312 5.42E-107 T 09-03-2017 L21SP3_RS07995 5c2aa5f5ddac47cc3561bac6fa014534 316 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 132 143 - T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 L21SP3_RS07995 5c2aa5f5ddac47cc3561bac6fa014534 316 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 312 5.7E-111 T 09-03-2017 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 L21SP3_RS07995 5c2aa5f5ddac47cc3561bac6fa014534 316 Gene3D G3DSA:3.20.20.70 1 312 1.0E-112 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SMART SM00086 368 408 0.056 T 09-03-2017 IPR001610 PAC motif L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SMART SM00086 221 264 6.3 T 09-03-2017 IPR001610 PAC motif L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Gene3D G3DSA:3.30.450.20 412 525 1.6E-19 T 09-03-2017 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SUPERFAMILY SSF52172 798 923 8.82E-33 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Pfam PF08448 PAS fold 152 266 8.2E-10 T 09-03-2017 IPR013656 PAS fold-4 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SMART SM00388 547 613 2.9E-25 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SMART SM00091 144 214 3.2 T 09-03-2017 IPR000014 PAS domain L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SMART SM00091 416 482 6.1E-5 T 09-03-2017 IPR000014 PAS domain L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SUPERFAMILY SSF55785 318 415 6.75E-8 T 09-03-2017 IPR000014 PAS domain L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Gene3D G3DSA:1.10.287.130 540 609 2.4E-19 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Pfam PF00072 Response regulator receiver domain 801 912 2.3E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Pfam PF00072 Response regulator receiver domain 8 119 6.9E-26 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SUPERFAMILY SSF55785 427 534 4.19E-19 T 09-03-2017 IPR000014 PAS domain L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SUPERFAMILY SSF55785 165 265 2.27E-9 T 09-03-2017 IPR000014 PAS domain L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 PRINTS PR00344 Bacterial sensor protein C-terminal signature 734 752 5.5E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 PRINTS PR00344 Bacterial sensor protein C-terminal signature 758 771 5.5E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 PRINTS PR00344 Bacterial sensor protein C-terminal signature 701 715 5.5E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 PRINTS PR00344 Bacterial sensor protein C-terminal signature 719 729 5.5E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Pfam PF00512 His Kinase A (phospho-acceptor) domain 547 613 1.6E-20 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Gene3D G3DSA:3.40.50.2300 797 924 1.7E-33 T 09-03-2017 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SMART SM00448 799 912 5.1E-30 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SMART SM00448 6 119 1.3E-39 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 661 771 1.0E-24 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Gene3D G3DSA:3.30.450.20 137 262 8.0E-12 T 09-03-2017 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Gene3D G3DSA:3.30.565.10 614 777 3.7E-41 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SUPERFAMILY SSF52172 6 172 1.05E-40 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Pfam PF13426 PAS domain 429 525 1.4E-8 T 09-03-2017 IPR000014 PAS domain L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Pfam PF13426 PAS domain 326 406 1.9 T 09-03-2017 IPR000014 PAS domain L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 422 534 1.0E-13 T 09-03-2017 IPR000014 PAS domain L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 142 271 3.7E-7 T 09-03-2017 IPR000014 PAS domain L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SUPERFAMILY SSF47384 532 614 2.35E-22 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SMART SM00387 660 774 5.3E-30 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 SUPERFAMILY SSF55874 602 770 9.3E-40 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Gene3D G3DSA:3.40.50.2300 2 125 1.4E-40 T 09-03-2017 L21SP3_RS06515 2b6d076e186d8e0de728eab28093cd29 1007 Gene3D G3DSA:3.30.450.20 283 411 4.4E-11 T 09-03-2017 L21SP3_RS10925 326fb45b23937c0cefd167a188fedd85 384 Gene3D G3DSA:3.40.50.2300 64 108 2.3E-4 T 09-03-2017 L21SP3_RS10925 326fb45b23937c0cefd167a188fedd85 384 SMART SM00342 294 377 6.0E-21 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS10925 326fb45b23937c0cefd167a188fedd85 384 SUPERFAMILY SSF46689 330 380 8.96E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS10925 326fb45b23937c0cefd167a188fedd85 384 SUPERFAMILY SSF53822 11 270 2.55E-33 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS10925 326fb45b23937c0cefd167a188fedd85 384 Gene3D G3DSA:1.10.10.60 331 381 2.4E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS10925 326fb45b23937c0cefd167a188fedd85 384 Pfam PF12833 Helix-turn-helix domain 301 378 4.6E-19 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS10925 326fb45b23937c0cefd167a188fedd85 384 Gene3D G3DSA:3.40.50.2300 109 271 2.0E-30 T 09-03-2017 L21SP3_RS10925 326fb45b23937c0cefd167a188fedd85 384 Pfam PF13377 Periplasmic binding protein-like domain 107 270 1.6E-29 T 09-03-2017 L21SP3_RS10925 326fb45b23937c0cefd167a188fedd85 384 Gene3D G3DSA:1.10.10.60 276 330 1.3E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS10325 df42dc5f82688add269b0b4a3a868d6c 429 SMART SM01091 345 424 2.0E-26 T 09-03-2017 IPR005170 Transporter-associated domain L21SP3_RS10325 df42dc5f82688add269b0b4a3a868d6c 429 SUPERFAMILY SSF54631 197 332 3.17E-32 T 09-03-2017 L21SP3_RS10325 df42dc5f82688add269b0b4a3a868d6c 429 Pfam PF01595 Domain of unknown function DUF21 11 194 7.5E-12 T 09-03-2017 IPR002550 Domain of unknown function DUF21 L21SP3_RS10325 df42dc5f82688add269b0b4a3a868d6c 429 Gene3D G3DSA:3.30.465.10 324 422 9.9E-29 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 L21SP3_RS10325 df42dc5f82688add269b0b4a3a868d6c 429 SUPERFAMILY SSF56176 344 425 2.21E-21 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 L21SP3_RS10325 df42dc5f82688add269b0b4a3a868d6c 429 Pfam PF03471 Transporter associated domain 348 423 2.4E-23 T 09-03-2017 IPR005170 Transporter-associated domain L21SP3_RS10325 df42dc5f82688add269b0b4a3a868d6c 429 Pfam PF00571 CBS domain 215 265 7.1E-6 T 09-03-2017 IPR000644 CBS domain L21SP3_RS10325 df42dc5f82688add269b0b4a3a868d6c 429 Pfam PF00571 CBS domain 283 329 5.9E-8 T 09-03-2017 IPR000644 CBS domain L21SP3_RS10325 df42dc5f82688add269b0b4a3a868d6c 429 SMART SM00116 218 267 0.0059 T 09-03-2017 IPR000644 CBS domain L21SP3_RS10325 df42dc5f82688add269b0b4a3a868d6c 429 SMART SM00116 281 329 3.5 T 09-03-2017 IPR000644 CBS domain L21SP3_RS10325 df42dc5f82688add269b0b4a3a868d6c 429 Gene3D G3DSA:3.10.580.10 196 323 1.3E-22 T 09-03-2017 L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 SMART SM00387 454 564 9.8E-27 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 SUPERFAMILY SSF55874 406 563 4.06E-38 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 Pfam PF14827 Double sensory domain of two-component sensor kinase 40 194 1.4E-10 T 09-03-2017 IPR029150 Double Cache domain 3 L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 SMART SM00304 277 330 2.4E-4 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 Pfam PF00512 His Kinase A (phospho-acceptor) domain 346 412 8.6E-9 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 SMART SM00388 345 413 9.3E-8 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 SUPERFAMILY SSF47384 335 412 1.53E-12 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 507 2.3E-14 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 563 2.3E-14 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 544 2.3E-14 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 SUPERFAMILY SSF103190 76 171 5.1E-5 T 09-03-2017 IPR029151 Periplasmic sensor domain-like L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 Gene3D G3DSA:3.30.565.10 412 563 3.2E-41 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 Pfam PF00672 HAMP domain 264 326 2.2E-8 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 Gene3D G3DSA:1.10.287.130 338 408 5.6E-8 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS02905 b4b7e1ac53ebebce57b651ea71fd48ba 564 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 454 563 1.9E-23 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS07485 1027fee20cafba44b63d2d9f8ef37520 354 SUPERFAMILY SSF47413 7 64 3.62E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS07485 1027fee20cafba44b63d2d9f8ef37520 354 SMART SM00354 6 70 4.1E-10 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 L21SP3_RS07485 1027fee20cafba44b63d2d9f8ef37520 354 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 56 3.2E-12 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 L21SP3_RS07485 1027fee20cafba44b63d2d9f8ef37520 354 SUPERFAMILY SSF53822 117 344 1.04E-36 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS07485 1027fee20cafba44b63d2d9f8ef37520 354 Gene3D G3DSA:3.40.50.2300 60 181 2.1E-6 T 09-03-2017 L21SP3_RS07485 1027fee20cafba44b63d2d9f8ef37520 354 Pfam PF13377 Periplasmic binding protein-like domain 184 342 3.5E-20 T 09-03-2017 L21SP3_RS07485 1027fee20cafba44b63d2d9f8ef37520 354 Gene3D G3DSA:1.10.260.40 7 59 2.6E-19 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS07485 1027fee20cafba44b63d2d9f8ef37520 354 Gene3D G3DSA:3.40.50.2300 182 343 1.7E-36 T 09-03-2017 L21SP3_RS09630 806d5b58c69289238032733dd7effd36 431 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 317 338 - T 09-03-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 L21SP3_RS09630 806d5b58c69289238032733dd7effd36 431 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 2 410 37.878 T 09-03-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 L21SP3_RS09630 806d5b58c69289238032733dd7effd36 431 PIRSF PIRSF000151 1 411 5.9E-167 T 09-03-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 L21SP3_RS09630 806d5b58c69289238032733dd7effd36 431 Gene3D G3DSA:3.40.309.10 221 368 2.6E-44 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 L21SP3_RS09630 806d5b58c69289238032733dd7effd36 431 SUPERFAMILY SSF53720 3 409 1.96E-114 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 L21SP3_RS09630 806d5b58c69289238032733dd7effd36 431 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 10 400 2.6E-152 T 09-03-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 L21SP3_RS09630 806d5b58c69289238032733dd7effd36 431 Pfam PF00171 Aldehyde dehydrogenase family 3 273 3.2E-17 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 L21SP3_RS09630 806d5b58c69289238032733dd7effd36 431 Gene3D G3DSA:3.40.605.10 3 219 2.0E-101 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 L21SP3_RS09630 806d5b58c69289238032733dd7effd36 431 Gene3D G3DSA:3.40.605.10 369 409 2.0E-101 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 L21SP3_RS04775 093114392403291ee1652a4dae6c97a1 377 Gene3D G3DSA:3.40.50.2000 1 196 2.5E-68 T 09-03-2017 L21SP3_RS04775 093114392403291ee1652a4dae6c97a1 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 24 358 1.0E-92 T 09-03-2017 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 L21SP3_RS04775 093114392403291ee1652a4dae6c97a1 377 Gene3D G3DSA:3.40.50.2000 197 359 8.1E-51 T 09-03-2017 L21SP3_RS04775 093114392403291ee1652a4dae6c97a1 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 339 2.1E-79 T 09-03-2017 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 L21SP3_RS04775 093114392403291ee1652a4dae6c97a1 377 SUPERFAMILY SSF53756 1 360 7.68E-107 T 09-03-2017 L21SP3_RS11065 53aa1f87dac4043661e37566b4737187 322 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 33 313 2.1E-85 T 09-03-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 L21SP3_RS11065 53aa1f87dac4043661e37566b4737187 322 Gene3D G3DSA:1.10.3720.10 42 316 8.8E-45 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS11065 53aa1f87dac4043661e37566b4737187 322 SUPERFAMILY SSF161098 39 308 5.89E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS11065 53aa1f87dac4043661e37566b4737187 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 315 1.7E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 Gene3D G3DSA:3.40.50.300 141 314 3.7E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 SUPERFAMILY SSF55785 15 121 4.36E-20 T 09-03-2017 IPR000014 PAS domain L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 Gene3D G3DSA:1.10.10.60 387 447 3.1E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 09-03-2017 IPR025944 Sigma-54 interaction domain, conserved site L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 SUPERFAMILY SSF52540 142 385 1.66E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 SUPERFAMILY SSF46689 355 446 1.15E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 09-03-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 SMART SM00382 162 305 1.2E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 Gene3D G3DSA:3.30.450.20 16 135 2.3E-21 T 09-03-2017 L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 Pfam PF13426 PAS domain 23 125 5.7E-13 T 09-03-2017 IPR000014 PAS domain L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 SMART SM00091 12 77 4.1E-6 T 09-03-2017 IPR000014 PAS domain L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 Pfam PF00158 Sigma-54 interaction domain 143 308 6.1E-67 T 09-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 Pfam PF02954 Bacterial regulatory protein, Fis family 406 443 8.1E-13 T 09-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 410 427 1.8E-10 T 09-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 427 447 1.8E-10 T 09-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 133 2.0E-13 T 09-03-2017 IPR000014 PAS domain L21SP3_RS09220 51413e353dac25a25c1fcaff3ba8b6ef 447 Gene3D G3DSA:1.10.8.60 315 386 3.4E-27 T 09-03-2017 L21SP3_RS00285 3bdadf559097f835a8f5b9448e5846eb 413 SUPERFAMILY SSF63411 219 405 1.52E-38 T 09-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 L21SP3_RS00285 3bdadf559097f835a8f5b9448e5846eb 413 Pfam PF05193 Peptidase M16 inactive domain 167 339 2.0E-25 T 09-03-2017 IPR007863 Peptidase M16, C-terminal L21SP3_RS00285 3bdadf559097f835a8f5b9448e5846eb 413 SUPERFAMILY SSF63411 6 207 1.92E-31 T 09-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 L21SP3_RS00285 3bdadf559097f835a8f5b9448e5846eb 413 Gene3D G3DSA:3.30.830.10 226 404 2.2E-38 T 09-03-2017 IPR011237 Peptidase M16 domain GO:0046872 L21SP3_RS00285 3bdadf559097f835a8f5b9448e5846eb 413 Gene3D G3DSA:3.30.830.10 5 211 1.7E-21 T 09-03-2017 IPR011237 Peptidase M16 domain GO:0046872 L21SP3_RS09425 a68261d817de92a6e21a4e0a4a84beb3 871 Gene3D G3DSA:2.60.120.260 668 813 1.3E-17 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09425 a68261d817de92a6e21a4e0a4a84beb3 871 Gene3D G3DSA:2.60.120.260 528 664 3.9E-13 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09425 a68261d817de92a6e21a4e0a4a84beb3 871 SUPERFAMILY SSF49785 666 812 1.87E-13 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09425 a68261d817de92a6e21a4e0a4a84beb3 871 SUPERFAMILY SSF51445 69 304 3.52E-17 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS09425 a68261d817de92a6e21a4e0a4a84beb3 871 Pfam PF03422 Carbohydrate binding module (family 6) 569 661 2.5E-5 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 L21SP3_RS09425 a68261d817de92a6e21a4e0a4a84beb3 871 Pfam PF03422 Carbohydrate binding module (family 6) 701 811 1.8E-5 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 L21SP3_RS09425 a68261d817de92a6e21a4e0a4a84beb3 871 SMART SM00606 665 812 0.0028 T 09-03-2017 IPR006584 Cellulose binding, type IV GO:0030246 L21SP3_RS09425 a68261d817de92a6e21a4e0a4a84beb3 871 Gene3D G3DSA:3.20.20.80 68 303 2.2E-9 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS09425 a68261d817de92a6e21a4e0a4a84beb3 871 SUPERFAMILY SSF49785 528 665 5.78E-9 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09425 a68261d817de92a6e21a4e0a4a84beb3 871 ProSitePatterns PS00018 EF-hand calcium-binding domain. 818 830 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS11250 7b80566bc110ca79a2fe877063c97495 269 Pfam PF04383 KilA-N domain 4 138 8.8E-26 T 09-03-2017 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding L21SP3_RS11250 7b80566bc110ca79a2fe877063c97495 269 SMART SM01252 10 139 1.1E-49 T 09-03-2017 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding L21SP3_RS00985 d06c2cb95f5aa57198d3f1818d5ffc83 282 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 7 281 37.092 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS00985 d06c2cb95f5aa57198d3f1818d5ffc83 282 Pfam PF01039 Carboxyl transferase domain 93 240 6.5E-15 T 09-03-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 L21SP3_RS00985 d06c2cb95f5aa57198d3f1818d5ffc83 282 Gene3D G3DSA:3.90.226.10 19 279 1.2E-71 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS00985 d06c2cb95f5aa57198d3f1818d5ffc83 282 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 1.3E-35 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS00985 d06c2cb95f5aa57198d3f1818d5ffc83 282 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 1.3E-35 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS00985 d06c2cb95f5aa57198d3f1818d5ffc83 282 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 1.3E-35 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS00985 d06c2cb95f5aa57198d3f1818d5ffc83 282 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 1.3E-35 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS00985 d06c2cb95f5aa57198d3f1818d5ffc83 282 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 1.3E-35 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS00985 d06c2cb95f5aa57198d3f1818d5ffc83 282 SUPERFAMILY SSF52096 24 280 1.24E-76 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS00985 d06c2cb95f5aa57198d3f1818d5ffc83 282 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 16 279 1.6E-113 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS07155 9dbdab4e5b2e97035b1360311e9ee028 243 SUPERFAMILY SSF53448 4 223 4.41E-44 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS07155 9dbdab4e5b2e97035b1360311e9ee028 243 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 224 1.7E-54 T 09-03-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 L21SP3_RS07155 9dbdab4e5b2e97035b1360311e9ee028 243 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 222 4.2E-59 T 09-03-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 L21SP3_RS07155 9dbdab4e5b2e97035b1360311e9ee028 243 Gene3D G3DSA:3.90.550.10 2 224 2.6E-55 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS07155 9dbdab4e5b2e97035b1360311e9ee028 243 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 226 23.589 T 09-03-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 L21SP3_RS02990 26d454b7fadcdd33505c12d530a7026f 248 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 8 237 8.4E-59 T 09-03-2017 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 L21SP3_RS02990 26d454b7fadcdd33505c12d530a7026f 248 Gene3D G3DSA:3.90.550.10 8 242 6.9E-64 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS02990 26d454b7fadcdd33505c12d530a7026f 248 Hamap MF_00057 3-deoxy-manno-octulosonate cytidylyltransferase [kdsB]. 6 247 34.54 T 09-03-2017 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 L21SP3_RS02990 26d454b7fadcdd33505c12d530a7026f 248 Pfam PF02348 Cytidylyltransferase 9 220 2.2E-53 T 09-03-2017 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 L21SP3_RS02990 26d454b7fadcdd33505c12d530a7026f 248 SUPERFAMILY SSF53448 7 240 9.15E-53 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS09545 560e0c20804532a53c1ff6c8596ac440 540 Gene3D G3DSA:3.30.1120.10 426 525 2.6E-18 T 09-03-2017 L21SP3_RS09545 560e0c20804532a53c1ff6c8596ac440 540 SUPERFAMILY SSF53649 38 524 4.94E-118 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09545 560e0c20804532a53c1ff6c8596ac440 540 Gene3D G3DSA:3.40.720.10 37 425 9.2E-102 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS09545 560e0c20804532a53c1ff6c8596ac440 540 Pfam PF00884 Sulfatase 40 412 1.4E-63 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS09545 560e0c20804532a53c1ff6c8596ac440 540 ProSitePatterns PS00523 Sulfatases signature 1. 91 103 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS09545 560e0c20804532a53c1ff6c8596ac440 540 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 18 0.0016 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal L21SP3_RS01580 38a3d40c1195a737f17a4c8c804e62fb 444 Pfam PF02601 Exonuclease VII, large subunit 122 436 4.2E-90 T 09-03-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 L21SP3_RS01580 38a3d40c1195a737f17a4c8c804e62fb 444 Pfam PF13742 OB-fold nucleic acid binding domain 5 98 1.7E-28 T 09-03-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 L21SP3_RS01580 38a3d40c1195a737f17a4c8c804e62fb 444 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 2 443 26.343 T 09-03-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 L21SP3_RS01580 38a3d40c1195a737f17a4c8c804e62fb 444 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 6 356 2.9E-122 T 09-03-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 L21SP3_RS09020 a42da5ca66ce763a1d2504df4c900b5b 629 SUPERFAMILY SSF75005 313 542 1.57E-28 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS09020 a42da5ca66ce763a1d2504df4c900b5b 629 Gene3D G3DSA:2.115.10.20 311 490 3.1E-24 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS09020 a42da5ca66ce763a1d2504df4c900b5b 629 Pfam PF04616 Glycosyl hydrolases family 43 311 502 5.4E-8 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS09020 a42da5ca66ce763a1d2504df4c900b5b 629 Gene3D G3DSA:2.115.10.20 491 524 5.5E-4 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS09020 a42da5ca66ce763a1d2504df4c900b5b 629 Gene3D G3DSA:2.115.10.20 563 600 5.5E-4 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS01895 47aad9ee0dba9a925de4b6b64fe3f1e6 282 Gene3D G3DSA:1.10.8.10 4 84 9.3E-18 T 09-03-2017 L21SP3_RS01895 47aad9ee0dba9a925de4b6b64fe3f1e6 282 SUPERFAMILY SSF53335 6 267 7.83E-45 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS01895 47aad9ee0dba9a925de4b6b64fe3f1e6 282 Pfam PF05175 Methyltransferase small domain 114 198 8.5E-15 T 09-03-2017 IPR007848 Methyltransferase small domain GO:0008168 L21SP3_RS01895 47aad9ee0dba9a925de4b6b64fe3f1e6 282 Gene3D G3DSA:3.40.50.150 90 280 7.5E-58 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS01895 47aad9ee0dba9a925de4b6b64fe3f1e6 282 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 6 282 35.76 T 09-03-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 L21SP3_RS01895 47aad9ee0dba9a925de4b6b64fe3f1e6 282 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 7 276 7.5E-61 T 09-03-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 L21SP3_RS01895 47aad9ee0dba9a925de4b6b64fe3f1e6 282 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 187 193 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 L21SP3_RS01895 47aad9ee0dba9a925de4b6b64fe3f1e6 282 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 29 278 4.3E-75 T 09-03-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 L21SP3_RS05490 4b4fc00d33fe1f4b5d72b099a149434b 368 SUPERFAMILY SSF53756 3 362 3.04E-75 T 09-03-2017 L21SP3_RS05490 4b4fc00d33fe1f4b5d72b099a149434b 368 Pfam PF13439 Glycosyltransferase Family 4 13 162 3.8E-25 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 L21SP3_RS05490 4b4fc00d33fe1f4b5d72b099a149434b 368 Pfam PF00534 Glycosyl transferases group 1 176 345 2.6E-32 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS05490 4b4fc00d33fe1f4b5d72b099a149434b 368 Gene3D G3DSA:3.40.50.2000 143 332 3.0E-27 T 09-03-2017 L21SP3_RS02035 5ee07085779e9c40c4d7e11cc144dc8e 499 Pfam PF01467 Cytidylyltransferase-like 368 460 5.2E-13 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP3_RS02035 5ee07085779e9c40c4d7e11cc144dc8e 499 Pfam PF00294 pfkB family carbohydrate kinase 23 324 6.7E-41 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB L21SP3_RS02035 5ee07085779e9c40c4d7e11cc144dc8e 499 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 355 495 2.0E-58 T 09-03-2017 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 L21SP3_RS02035 5ee07085779e9c40c4d7e11cc144dc8e 499 Hamap MF_01603 Bifunctional protein HldE [hldE]. 15 497 37.088 T 09-03-2017 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 L21SP3_RS02035 5ee07085779e9c40c4d7e11cc144dc8e 499 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 365 430 4.2E-14 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP3_RS02035 5ee07085779e9c40c4d7e11cc144dc8e 499 SUPERFAMILY SSF53613 22 335 1.87E-51 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS02035 5ee07085779e9c40c4d7e11cc144dc8e 499 Gene3D G3DSA:3.40.50.620 363 484 1.5E-32 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS02035 5ee07085779e9c40c4d7e11cc144dc8e 499 Gene3D G3DSA:3.40.1190.20 23 335 3.7E-58 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS02035 5ee07085779e9c40c4d7e11cc144dc8e 499 SUPERFAMILY SSF52374 363 493 8.59E-23 T 09-03-2017 L21SP3_RS03080 ada323939384bc5a475f4364ec3437b9 302 TIGRFAM TIGR00510 lipA: lipoyl synthase 21 301 7.0E-100 T 09-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 L21SP3_RS03080 ada323939384bc5a475f4364ec3437b9 302 SMART SM00729 72 280 1.1E-12 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP3_RS03080 ada323939384bc5a475f4364ec3437b9 302 Gene3D G3DSA:3.20.20.70 40 301 3.8E-50 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS03080 ada323939384bc5a475f4364ec3437b9 302 Hamap MF_00206 Lipoyl synthase [lipA]. 1 302 108.314 T 09-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 L21SP3_RS03080 ada323939384bc5a475f4364ec3437b9 302 SUPERFAMILY SSF102114 40 299 1.18E-45 T 09-03-2017 L21SP3_RS03080 ada323939384bc5a475f4364ec3437b9 302 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 19 61 1.4E-6 T 09-03-2017 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 L21SP3_RS03080 ada323939384bc5a475f4364ec3437b9 302 Pfam PF04055 Radical SAM superfamily 79 240 3.0E-12 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS04560 f586f61f1f66b2fe52dc3c0a2efa1ac8 308 SUPERFAMILY SSF51569 9 301 3.77E-39 T 09-03-2017 L21SP3_RS04560 f586f61f1f66b2fe52dc3c0a2efa1ac8 308 SMART SM01130 8 303 6.7E-14 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS04560 f586f61f1f66b2fe52dc3c0a2efa1ac8 308 Gene3D G3DSA:3.20.20.70 9 301 3.1E-39 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS04560 f586f61f1f66b2fe52dc3c0a2efa1ac8 308 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 44 61 - T 09-03-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS04560 f586f61f1f66b2fe52dc3c0a2efa1ac8 308 Pfam PF00701 Dihydrodipicolinate synthetase family 21 250 1.3E-18 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS04560 f586f61f1f66b2fe52dc3c0a2efa1ac8 308 PIRSF PIRSF001365 5 305 5.4E-36 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS11790 b8b4f27db923213b46e86f5775f0143e 177 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 10 161 1.1E-43 T 09-03-2017 IPR023635 Peptide deformylase L21SP3_RS11790 b8b4f27db923213b46e86f5775f0143e 177 SUPERFAMILY SSF56420 8 166 9.03E-49 T 09-03-2017 IPR023635 Peptide deformylase L21SP3_RS11790 b8b4f27db923213b46e86f5775f0143e 177 Gene3D G3DSA:3.90.45.10 11 166 1.6E-50 T 09-03-2017 IPR023635 Peptide deformylase L21SP3_RS11790 b8b4f27db923213b46e86f5775f0143e 177 PIRSF PIRSF004749 3 174 1.1E-43 T 09-03-2017 IPR023635 Peptide deformylase L21SP3_RS11790 b8b4f27db923213b46e86f5775f0143e 177 Pfam PF01327 Polypeptide deformylase 12 154 2.7E-44 T 09-03-2017 IPR023635 Peptide deformylase L21SP3_RS11790 b8b4f27db923213b46e86f5775f0143e 177 PRINTS PR01576 Peptide deformylase signature 123 152 6.1E-30 T 09-03-2017 IPR023635 Peptide deformylase L21SP3_RS11790 b8b4f27db923213b46e86f5775f0143e 177 PRINTS PR01576 Peptide deformylase signature 36 65 6.1E-30 T 09-03-2017 IPR023635 Peptide deformylase L21SP3_RS11790 b8b4f27db923213b46e86f5775f0143e 177 PRINTS PR01576 Peptide deformylase signature 104 122 6.1E-30 T 09-03-2017 IPR023635 Peptide deformylase L21SP3_RS11790 b8b4f27db923213b46e86f5775f0143e 177 PRINTS PR01576 Peptide deformylase signature 92 103 6.1E-30 T 09-03-2017 IPR023635 Peptide deformylase L21SP3_RS11790 b8b4f27db923213b46e86f5775f0143e 177 Hamap MF_00163 Peptide deformylase [def]. 5 165 25.597 T 09-03-2017 IPR023635 Peptide deformylase L21SP3_RS01485 30cf6f606e17c5f4d428a7cd01eeb376 329 Hamap MF_01590 tRNA U34 carboxymethyltransferase [cmoB]. 12 329 46.178 T 09-03-2017 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 L21SP3_RS01485 30cf6f606e17c5f4d428a7cd01eeb376 329 Pfam PF08003 Protein of unknown function (DUF1698) 16 328 9.9E-111 T 09-03-2017 IPR027555 tRNA (mo5U34)-methyltransferase-like L21SP3_RS01485 30cf6f606e17c5f4d428a7cd01eeb376 329 SUPERFAMILY SSF53335 98 304 2.28E-25 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS01485 30cf6f606e17c5f4d428a7cd01eeb376 329 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 17 326 7.6E-122 T 09-03-2017 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 L21SP3_RS01485 30cf6f606e17c5f4d428a7cd01eeb376 329 Gene3D G3DSA:3.40.50.150 118 324 6.5E-21 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS09755 ad4510d4b56468e1b8ac7768d65a3bd0 474 Gene3D G3DSA:3.90.190.20 326 470 1.1E-48 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS09755 ad4510d4b56468e1b8ac7768d65a3bd0 474 Gene3D G3DSA:3.40.1190.10 98 325 8.0E-63 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS09755 ad4510d4b56468e1b8ac7768d65a3bd0 474 Gene3D G3DSA:3.40.50.720 7 96 1.8E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS09755 ad4510d4b56468e1b8ac7768d65a3bd0 474 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 6 472 35.247 T 09-03-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS09755 ad4510d4b56468e1b8ac7768d65a3bd0 474 Pfam PF08245 Mur ligase middle domain 115 302 2.9E-27 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS09755 ad4510d4b56468e1b8ac7768d65a3bd0 474 SUPERFAMILY SSF51984 7 96 1.31E-22 T 09-03-2017 L21SP3_RS09755 ad4510d4b56468e1b8ac7768d65a3bd0 474 SUPERFAMILY SSF53244 322 469 5.49E-39 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS09755 ad4510d4b56468e1b8ac7768d65a3bd0 474 SUPERFAMILY SSF53623 95 315 1.83E-52 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS09755 ad4510d4b56468e1b8ac7768d65a3bd0 474 Pfam PF02875 Mur ligase family, glutamate ligase domain 324 401 4.2E-19 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS09755 ad4510d4b56468e1b8ac7768d65a3bd0 474 Pfam PF01225 Mur ligase family, catalytic domain 9 109 1.5E-17 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 L21SP3_RS09755 ad4510d4b56468e1b8ac7768d65a3bd0 474 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 8 465 2.0E-125 T 09-03-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS03890 7a2225caf81c4e55d541d5ae713772c0 493 SUPERFAMILY SSF53067 253 487 9.84E-37 T 09-03-2017 L21SP3_RS03890 7a2225caf81c4e55d541d5ae713772c0 493 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 447 8.9E-12 T 09-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 L21SP3_RS03890 7a2225caf81c4e55d541d5ae713772c0 493 PIRSF PIRSF000538 1 493 1.5E-102 T 09-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 L21SP3_RS03890 7a2225caf81c4e55d541d5ae713772c0 493 Gene3D G3DSA:3.30.420.40 252 490 8.5E-30 T 09-03-2017 L21SP3_RS03890 7a2225caf81c4e55d541d5ae713772c0 493 Gene3D G3DSA:3.30.420.40 2 246 7.2E-55 T 09-03-2017 L21SP3_RS03890 7a2225caf81c4e55d541d5ae713772c0 493 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 2 247 2.1E-53 T 09-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 L21SP3_RS03890 7a2225caf81c4e55d541d5ae713772c0 493 SUPERFAMILY SSF53067 2 251 2.2E-57 T 09-03-2017 L21SP3_RS09435 549571ad3088db38bb2791570d681865 638 Pfam PF02719 Polysaccharide biosynthesis protein 306 587 1.4E-117 T 09-03-2017 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain L21SP3_RS09435 549571ad3088db38bb2791570d681865 638 Gene3D G3DSA:3.40.50.720 158 241 8.5E-12 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS09435 549571ad3088db38bb2791570d681865 638 SUPERFAMILY SSF51735 303 565 9.27E-57 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS09435 549571ad3088db38bb2791570d681865 638 Gene3D G3DSA:3.40.50.720 304 485 8.9E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS09435 549571ad3088db38bb2791570d681865 638 Pfam PF13727 CoA-binding domain 106 261 5.7E-11 T 09-03-2017 L21SP3_RS09435 549571ad3088db38bb2791570d681865 638 Gene3D G3DSA:3.90.25.10 486 589 6.3E-8 T 09-03-2017 L21SP3_RS09435 549571ad3088db38bb2791570d681865 638 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 304 459 0.0036 T 09-03-2017 L21SP3_RS09435 549571ad3088db38bb2791570d681865 638 SUPERFAMILY SSF53335 161 345 7.14E-13 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS00890 b024ee733cbb3ebe9361fc74fe611c4f 285 Pfam PF13633 Prokaryotic N-terminal methylation site 4 29 1.7E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS00890 b024ee733cbb3ebe9361fc74fe611c4f 285 Gene3D G3DSA:3.30.700.10 6 39 2.9E-5 T 09-03-2017 L21SP3_RS00890 b024ee733cbb3ebe9361fc74fe611c4f 285 SUPERFAMILY SSF54523 6 86 3.3E-13 T 09-03-2017 L21SP3_RS00890 b024ee733cbb3ebe9361fc74fe611c4f 285 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 25 1.4E-6 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS08215 a5a0f1b76d88ff07cb0dac307b10cdf5 299 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 216 297 4.0E-7 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal L21SP3_RS08215 a5a0f1b76d88ff07cb0dac307b10cdf5 299 Gene3D G3DSA:3.40.50.300 3 198 4.5E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08215 a5a0f1b76d88ff07cb0dac307b10cdf5 299 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 180 1.1E-36 T 09-03-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain L21SP3_RS08215 a5a0f1b76d88ff07cb0dac307b10cdf5 299 Gene3D G3DSA:3.30.1220.10 212 297 3.8E-4 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal L21SP3_RS08215 a5a0f1b76d88ff07cb0dac307b10cdf5 299 SUPERFAMILY SSF52540 4 180 9.95E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08215 a5a0f1b76d88ff07cb0dac307b10cdf5 299 SUPERFAMILY SSF90002 216 297 2.22E-7 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal L21SP3_RS06135 8e1f17ed172b5e5d23c0be882f42d2a8 188 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 185 9.3E-62 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP3_RS06135 8e1f17ed172b5e5d23c0be882f42d2a8 188 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 185 33.792 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP3_RS06135 8e1f17ed172b5e5d23c0be882f42d2a8 188 SUPERFAMILY SSF56053 84 185 5.23E-26 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06135 8e1f17ed172b5e5d23c0be882f42d2a8 188 SUPERFAMILY SSF56053 1 83 7.72E-23 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06135 8e1f17ed172b5e5d23c0be882f42d2a8 188 Pfam PF00347 Ribosomal protein L6 91 173 1.9E-14 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06135 8e1f17ed172b5e5d23c0be882f42d2a8 188 Pfam PF00347 Ribosomal protein L6 12 83 5.0E-16 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06135 8e1f17ed172b5e5d23c0be882f42d2a8 188 PRINTS PR00059 Ribosomal protein L6 signature 150 171 5.8E-21 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP3_RS06135 8e1f17ed172b5e5d23c0be882f42d2a8 188 PRINTS PR00059 Ribosomal protein L6 signature 72 97 5.8E-21 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP3_RS06135 8e1f17ed172b5e5d23c0be882f42d2a8 188 Gene3D G3DSA:3.90.930.12 2 83 1.1E-27 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06135 8e1f17ed172b5e5d23c0be882f42d2a8 188 PIRSF PIRSF002162 1 186 5.6E-42 T 09-03-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06135 8e1f17ed172b5e5d23c0be882f42d2a8 188 Gene3D G3DSA:3.90.930.12 84 185 1.4E-29 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS04830 1a5b73f1df3feb0b78ba8fded7a43ac9 420 Pfam PF00534 Glycosyl transferases group 1 219 394 2.4E-24 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS04830 1a5b73f1df3feb0b78ba8fded7a43ac9 420 Gene3D G3DSA:3.40.50.2000 238 392 8.0E-12 T 09-03-2017 L21SP3_RS04830 1a5b73f1df3feb0b78ba8fded7a43ac9 420 SUPERFAMILY SSF53756 40 417 3.49E-44 T 09-03-2017 L21SP3_RS09155 cc3b768bc9e25868788a3a654fd84e7d 368 SMART SM00382 134 259 0.0095 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS09155 cc3b768bc9e25868788a3a654fd84e7d 368 Pfam PF00437 Type II/IV secretion system protein 10 268 2.2E-39 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS09155 cc3b768bc9e25868788a3a654fd84e7d 368 Gene3D G3DSA:3.40.50.300 112 357 3.7E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09155 cc3b768bc9e25868788a3a654fd84e7d 368 SUPERFAMILY SSF52540 3 345 1.09E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09155 cc3b768bc9e25868788a3a654fd84e7d 368 Gene3D G3DSA:3.30.450.90 3 107 1.1E-4 T 09-03-2017 L21SP3_RS09155 cc3b768bc9e25868788a3a654fd84e7d 368 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 4 357 8.4E-107 T 09-03-2017 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 31 557 2.2E-229 T 09-03-2017 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 30 339 1.9E-113 T 09-03-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 Gene3D G3DSA:2.40.240.10 465 553 5.7E-32 T 09-03-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 Gene3D G3DSA:3.90.800.10 104 212 8.3E-50 T 09-03-2017 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 PRINTS PR00987 Glutamyl-tRNA synthetase signature 34 46 2.2E-7 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 PRINTS PR00987 Glutamyl-tRNA synthetase signature 63 76 2.2E-7 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 PRINTS PR00987 Glutamyl-tRNA synthetase signature 213 223 2.2E-7 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 SUPERFAMILY SSF52374 30 348 7.6E-104 T 09-03-2017 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 Gene3D G3DSA:1.10.1160.10 265 340 1.9E-36 T 09-03-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 342 535 4.0E-59 T 09-03-2017 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 SUPERFAMILY SSF50715 342 553 3.66E-71 T 09-03-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 37 48 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 Gene3D G3DSA:2.40.240.10 350 464 2.1E-46 T 09-03-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 555 52.209 T 09-03-2017 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 Gene3D G3DSA:3.40.50.620 30 99 1.8E-43 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS07300 5736924b481a3b36014d4592eec1fd95 567 Gene3D G3DSA:3.40.50.620 215 264 1.8E-43 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS07460 fd40bfcd1c7a6778d8082f717cec8c9e 96 SMART SM00418 9 87 2.0E-16 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP3_RS07460 fd40bfcd1c7a6778d8082f717cec8c9e 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 4.7E-11 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP3_RS07460 fd40bfcd1c7a6778d8082f717cec8c9e 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 30 41 4.7E-11 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP3_RS07460 fd40bfcd1c7a6778d8082f717cec8c9e 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 4.7E-11 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP3_RS07460 fd40bfcd1c7a6778d8082f717cec8c9e 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 4.7E-11 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP3_RS07460 fd40bfcd1c7a6778d8082f717cec8c9e 96 Pfam PF01022 Bacterial regulatory protein, arsR family 18 61 1.2E-14 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP3_RS07460 fd40bfcd1c7a6778d8082f717cec8c9e 96 Gene3D G3DSA:1.10.10.10 3 91 4.9E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS07460 fd40bfcd1c7a6778d8082f717cec8c9e 96 SUPERFAMILY SSF46785 6 89 5.55E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 ProSitePatterns PS00018 EF-hand calcium-binding domain. 1469 1481 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 ProSitePatterns PS00018 EF-hand calcium-binding domain. 1427 1439 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 1281 1326 0.0017 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 821 881 1.3E-5 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 1018 1079 1.6E-4 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 2100 2159 1.1E-4 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 887 947 7.9E-5 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 1150 1208 6.0E-4 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 1216 1264 2.3E-4 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 952 1012 1.3E-4 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 1084 1142 6.0E-4 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 2165 2225 0.12 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 1348 1413 6.6E-5 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 2230 2288 0.0071 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS05865 a00f791cffd7f40b4c4ddb70071e8761 2497 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 2036 2079 0.15 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 SUPERFAMILY SSF54292 4 76 3.0E-20 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 227 508 1.1E-90 T 09-03-2017 IPR004108 Iron hydrogenase, large subunit, C-terminal L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 33 50 - T 09-03-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 85 123 3.3E-14 T 09-03-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 191 202 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 Gene3D G3DSA:4.10.260.20 521 578 1.5E-23 T 09-03-2017 IPR003149 Iron hydrogenase, small subunit L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 Gene3D G3DSA:3.40.50.1780 196 249 2.1E-67 T 09-03-2017 L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 Gene3D G3DSA:3.40.50.1780 301 431 2.1E-67 T 09-03-2017 L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 78 1.6E-20 T 09-03-2017 L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 140 511 7.8E-155 T 09-03-2017 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 SMART SM00902 519 578 3.4E-22 T 09-03-2017 IPR003149 Iron hydrogenase, small subunit L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 SMART SM00929 85 125 3.9E-14 T 09-03-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 SUPERFAMILY SSF54862 77 208 7.53E-34 T 09-03-2017 L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 Gene3D G3DSA:3.30.70.20 134 195 2.2E-11 T 09-03-2017 L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 SUPERFAMILY SSF53920 191 575 1.7E-127 T 09-03-2017 IPR009016 Iron hydrogenase L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 Pfam PF02256 Iron hydrogenase small subunit 523 577 8.4E-23 T 09-03-2017 IPR003149 Iron hydrogenase, small subunit L21SP3_RS01545 3be8b3cae737a419169b43fcc2b0b636 591 Gene3D G3DSA:3.10.20.30 3 57 7.9E-7 T 09-03-2017 IPR012675 Beta-grasp domain L21SP3_RS06225 02dc53404d678dcf78f1e5962d7b72bf 625 SUPERFAMILY SSF48208 83 348 4.25E-18 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS06225 02dc53404d678dcf78f1e5962d7b72bf 625 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 41 532 1.8E-48 T 09-03-2017 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP3_RS06225 02dc53404d678dcf78f1e5962d7b72bf 625 Gene3D G3DSA:1.50.10.10 114 291 3.0E-9 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS06345 2dffbc65d9d67d3670ce5e33409f9a24 169 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 128 141 3.2E-15 T 09-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 L21SP3_RS06345 2dffbc65d9d67d3670ce5e33409f9a24 169 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 96 109 3.2E-15 T 09-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 L21SP3_RS06345 2dffbc65d9d67d3670ce5e33409f9a24 169 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 113 127 3.2E-15 T 09-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 L21SP3_RS06345 2dffbc65d9d67d3670ce5e33409f9a24 169 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 9 167 3.9E-44 T 09-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 L21SP3_RS06345 2dffbc65d9d67d3670ce5e33409f9a24 169 Gene3D G3DSA:2.40.50.100 91 166 4.4E-27 T 09-03-2017 L21SP3_RS06345 2dffbc65d9d67d3670ce5e33409f9a24 169 SUPERFAMILY SSF51230 92 166 9.68E-22 T 09-03-2017 IPR011053 Single hybrid motif L21SP3_RS06345 2dffbc65d9d67d3670ce5e33409f9a24 169 Pfam PF00364 Biotin-requiring enzyme 94 165 3.9E-21 T 09-03-2017 IPR000089 Biotin/lipoyl attachment L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 PRINTS PR00985 Leucyl-tRNA synthetase signature 604 614 1.1E-54 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 PRINTS PR00985 Leucyl-tRNA synthetase signature 192 208 1.1E-54 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 PRINTS PR00985 Leucyl-tRNA synthetase signature 130 147 1.1E-54 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 PRINTS PR00985 Leucyl-tRNA synthetase signature 571 593 1.1E-54 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 PRINTS PR00985 Leucyl-tRNA synthetase signature 224 237 1.1E-54 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 PRINTS PR00985 Leucyl-tRNA synthetase signature 253 272 1.1E-54 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 PRINTS PR00985 Leucyl-tRNA synthetase signature 532 550 1.1E-54 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 Gene3D G3DSA:3.90.740.10 262 467 3.0E-56 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 46 56 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 SUPERFAMILY SSF52374 459 671 7.72E-133 T 09-03-2017 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 SUPERFAMILY SSF52374 4 150 7.72E-133 T 09-03-2017 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 SUPERFAMILY SSF52374 187 264 7.72E-133 T 09-03-2017 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 SUPERFAMILY SSF47323 666 852 2.99E-30 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 147 5.6E-16 T 09-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 460 649 6.2E-22 T 09-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 Gene3D G3DSA:3.40.50.620 5 149 5.5E-160 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 Gene3D G3DSA:3.40.50.620 468 651 5.5E-160 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 Gene3D G3DSA:3.40.50.620 186 261 5.5E-160 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 6 853 22.483 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 Pfam PF08264 Anticodon-binding domain of tRNA 706 813 5.9E-16 T 09-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 SUPERFAMILY SSF50677 264 458 2.51E-54 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 260 447 9.6E-68 T 09-03-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 186 852 4.1E-248 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 L21SP3_RS07115 b36eef5947007536b46f4c8ee5c2bcac 853 Gene3D G3DSA:1.10.730.10 652 788 6.1E-39 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS01140 e2d0f6cdb1b5623f953d6e93e4e44567 244 SUPERFAMILY SSF53335 21 244 2.32E-29 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS01140 e2d0f6cdb1b5623f953d6e93e4e44567 244 Gene3D G3DSA:3.40.50.150 21 244 7.5E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS01140 e2d0f6cdb1b5623f953d6e93e4e44567 244 Hamap MF_01589 Carboxy-S-adenosyl-L-methionine synthase [cmoA]. 4 244 38.145 T 09-03-2017 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 L21SP3_RS01140 e2d0f6cdb1b5623f953d6e93e4e44567 244 Pfam PF13649 Methyltransferase domain 63 160 5.3E-10 T 09-03-2017 L21SP3_RS01140 e2d0f6cdb1b5623f953d6e93e4e44567 244 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 5 244 4.6E-80 T 09-03-2017 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 L21SP3_RS01140 e2d0f6cdb1b5623f953d6e93e4e44567 244 PIRSF PIRSF006325 2 244 6.5E-91 T 09-03-2017 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 SMART SM00836 462 584 1.6E-34 T 09-03-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 Pfam PF00750 tRNA synthetases class I (R) 114 448 6.1E-125 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 SUPERFAMILY SSF47323 456 584 2.22E-28 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 Gene3D G3DSA:3.30.1360.70 6 104 3.9E-28 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 7 584 2.3E-165 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 124 135 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 SUPERFAMILY SSF55190 5 106 1.7E-23 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 8 87 3.8E-21 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 Gene3D G3DSA:1.10.730.10 456 584 8.3E-33 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 Hamap MF_00123 Arginine--tRNA ligase [argS]. 6 584 25.489 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 SMART SM01016 6 87 7.3E-27 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 Gene3D G3DSA:3.40.50.620 113 454 2.7E-111 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 PRINTS PR01038 Arginyl-tRNA synthetase signature 116 131 5.9E-27 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 PRINTS PR01038 Arginyl-tRNA synthetase signature 155 168 5.9E-27 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 5.9E-27 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 PRINTS PR01038 Arginyl-tRNA synthetase signature 131 147 5.9E-27 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 Pfam PF05746 DALR anticodon binding domain 462 584 5.0E-28 T 09-03-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 L21SP3_RS09825 9927dda8b195f049de832f4c2c7e5c7a 584 SUPERFAMILY SSF52374 114 454 1.86E-90 T 09-03-2017 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 Gene3D G3DSA:1.10.1040.10 182 435 1.6E-121 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 254 266 - T 09-03-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 Gene3D G3DSA:1.20.5.320 436 481 1.1E-25 T 09-03-2017 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 SUPERFAMILY SSF51735 4 175 2.96E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 PIRSF PIRSF000109 1 478 3.3E-242 T 09-03-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 470 1.0E-232 T 09-03-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 67 96 1.6E-83 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 120 145 1.6E-83 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 1.6E-83 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 169 197 1.6E-83 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 250 277 1.6E-83 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 357 379 1.6E-83 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 173 1.6E-49 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 SUPERFAMILY SSF48179 178 473 2.93E-132 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 180 469 9.9E-132 T 09-03-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 SMART SM01350 180 470 6.1E-227 T 09-03-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 L21SP3_RS02860 6a6316ea401806d0c2a78e8bf4d34e91 483 Gene3D G3DSA:3.40.50.720 1 181 7.2E-55 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS03065 1506f2bb17ee5960089430d7e9ea2ca0 449 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 8 445 29.028 T 09-03-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS03065 1506f2bb17ee5960089430d7e9ea2ca0 449 Gene3D G3DSA:3.40.1190.10 120 254 3.5E-36 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS03065 1506f2bb17ee5960089430d7e9ea2ca0 449 Pfam PF02875 Mur ligase family, glutamate ligase domain 305 374 2.4E-6 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS03065 1506f2bb17ee5960089430d7e9ea2ca0 449 Pfam PF08245 Mur ligase middle domain 116 257 9.6E-31 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS03065 1506f2bb17ee5960089430d7e9ea2ca0 449 Gene3D G3DSA:3.90.190.20 306 441 4.9E-40 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS03065 1506f2bb17ee5960089430d7e9ea2ca0 449 Gene3D G3DSA:3.40.1190.10 84 119 1.2E-5 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS03065 1506f2bb17ee5960089430d7e9ea2ca0 449 Gene3D G3DSA:3.40.50.720 5 83 1.6E-9 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS03065 1506f2bb17ee5960089430d7e9ea2ca0 449 SUPERFAMILY SSF53623 103 301 4.06E-41 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS03065 1506f2bb17ee5960089430d7e9ea2ca0 449 SUPERFAMILY SSF53244 304 444 4.27E-36 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS03065 1506f2bb17ee5960089430d7e9ea2ca0 449 Gene3D G3DSA:3.40.1190.10 265 305 2.1E-6 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS03065 1506f2bb17ee5960089430d7e9ea2ca0 449 SUPERFAMILY SSF51984 8 98 7.85E-9 T 09-03-2017 L21SP3_RS03065 1506f2bb17ee5960089430d7e9ea2ca0 449 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 9 443 4.3E-109 T 09-03-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS09750 7eb22548ef793586f6762373bbb5435c 40 Pfam PF13633 Prokaryotic N-terminal methylation site 3 29 9.8E-10 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS09750 7eb22548ef793586f6762373bbb5435c 40 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 25 2.5E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS09750 7eb22548ef793586f6762373bbb5435c 40 SUPERFAMILY SSF54523 6 39 2.35E-10 T 09-03-2017 L21SP3_RS09750 7eb22548ef793586f6762373bbb5435c 40 Gene3D G3DSA:3.30.700.10 6 39 1.4E-6 T 09-03-2017 L21SP3_RS00880 5f4e4e43f8cbd9e9571d3bee872b49f8 476 SUPERFAMILY SSF53649 30 469 3.05E-113 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS00880 5f4e4e43f8cbd9e9571d3bee872b49f8 476 ProSitePatterns PS00523 Sulfatases signature 1. 78 90 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS00880 5f4e4e43f8cbd9e9571d3bee872b49f8 476 Pfam PF00884 Sulfatase 32 364 2.0E-52 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS00880 5f4e4e43f8cbd9e9571d3bee872b49f8 476 Gene3D G3DSA:3.40.720.10 29 383 6.4E-92 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS00880 5f4e4e43f8cbd9e9571d3bee872b49f8 476 Gene3D G3DSA:3.30.1120.10 387 469 1.8E-20 T 09-03-2017 L21SP3_RS10305 5b927f58c0403f934383cbf589823a7c 338 Pfam PF13936 Helix-turn-helix domain 3 45 5.1E-14 T 09-03-2017 IPR025246 Transposase IS30-like HTH domain L21SP3_RS10305 5b927f58c0403f934383cbf589823a7c 338 Pfam PF00665 Integrase core domain 178 280 8.4E-13 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS10305 5b927f58c0403f934383cbf589823a7c 338 SUPERFAMILY SSF53098 175 321 1.67E-24 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS10305 5b927f58c0403f934383cbf589823a7c 338 Gene3D G3DSA:3.30.420.10 176 322 3.0E-13 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS10305 5b927f58c0403f934383cbf589823a7c 338 ProSitePatterns PS01043 Transposases, IS30 family, signature. 268 284 - T 09-03-2017 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 L21SP3_RS01510 b84e0b8f02242c49d29b774e8665f49c 279 SUPERFAMILY SSF54523 6 87 1.49E-12 T 09-03-2017 L21SP3_RS01510 b84e0b8f02242c49d29b774e8665f49c 279 Pfam PF13633 Prokaryotic N-terminal methylation site 4 29 3.2E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS01510 b84e0b8f02242c49d29b774e8665f49c 279 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 25 1.8E-6 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS01510 b84e0b8f02242c49d29b774e8665f49c 279 Gene3D G3DSA:3.30.700.10 6 59 4.1E-5 T 09-03-2017 L21SP3_RS01510 b84e0b8f02242c49d29b774e8665f49c 279 PRINTS PR00813 Bacterial general secretion pathway protein G signature 41 59 1.4E-5 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS01510 b84e0b8f02242c49d29b774e8665f49c 279 PRINTS PR00813 Bacterial general secretion pathway protein G signature 5 30 1.4E-5 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS09840 b95235f93d7c5ead5e604aae6230982f 316 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 7 308 25.879 T 09-03-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 L21SP3_RS09840 b95235f93d7c5ead5e604aae6230982f 316 SUPERFAMILY SSF52540 8 162 4.38E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09840 b95235f93d7c5ead5e604aae6230982f 316 Gene3D G3DSA:1.10.287.890 206 281 9.6E-24 T 09-03-2017 L21SP3_RS09840 b95235f93d7c5ead5e604aae6230982f 316 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 8 292 5.0E-85 T 09-03-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 L21SP3_RS09840 b95235f93d7c5ead5e604aae6230982f 316 Gene3D G3DSA:3.40.50.300 5 174 1.4E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09840 b95235f93d7c5ead5e604aae6230982f 316 Pfam PF01715 IPP transferase 41 284 8.3E-72 T 09-03-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 L21SP3_RS09840 b95235f93d7c5ead5e604aae6230982f 316 SUPERFAMILY SSF52540 168 267 1.32E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09840 b95235f93d7c5ead5e604aae6230982f 316 SUPERFAMILY SSF52540 6 65 1.32E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09610 96ee7eea3517c748beb114b367a66b8c 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.6E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS09610 96ee7eea3517c748beb114b367a66b8c 422 Pfam PF01609 Transposase DDE domain 275 412 3.3E-7 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS03055 ac9d8c74db944ef0b45f27ad5d87da04 67 Pfam PF02609 Exonuclease VII small subunit 13 64 1.8E-18 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 L21SP3_RS03055 ac9d8c74db944ef0b45f27ad5d87da04 67 PIRSF PIRSF006488 3 67 2.0E-21 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 L21SP3_RS03055 ac9d8c74db944ef0b45f27ad5d87da04 67 SUPERFAMILY SSF116842 6 66 7.19E-19 T 09-03-2017 L21SP3_RS03055 ac9d8c74db944ef0b45f27ad5d87da04 67 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 12 66 7.7E-21 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 L21SP3_RS03055 ac9d8c74db944ef0b45f27ad5d87da04 67 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 12 67 11.968 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 L21SP3_RS03055 ac9d8c74db944ef0b45f27ad5d87da04 67 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 12 51 2.0E-5 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 L21SP3_RS03055 ac9d8c74db944ef0b45f27ad5d87da04 67 Gene3D G3DSA:1.10.287.1040 7 66 3.9E-21 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 SUPERFAMILY SSF47384 350 429 8.44E-20 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 SMART SM00388 363 430 3.8E-21 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 SUPERFAMILY SSF55874 420 588 1.11E-46 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 481 588 1.8E-28 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 528 2.0E-17 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 542 2.0E-17 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 567 2.0E-17 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 PRINTS PR00344 Bacterial sensor protein C-terminal signature 574 587 2.0E-17 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 SUPERFAMILY SSF158472 192 239 2.75E-6 T 09-03-2017 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 Gene3D G3DSA:1.10.287.130 355 416 2.6E-21 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 Pfam PF00512 His Kinase A (phospho-acceptor) domain 364 429 3.0E-20 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 Gene3D G3DSA:3.30.450.20 245 354 8.1E-11 T 09-03-2017 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 SMART SM00304 190 242 2.2E-7 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 Gene3D G3DSA:3.30.565.10 417 588 1.4E-47 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 251 361 1.6E-5 T 09-03-2017 IPR000014 PAS domain L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 SUPERFAMILY SSF55785 260 362 1.6E-6 T 09-03-2017 IPR000014 PAS domain L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 Pfam PF00672 HAMP domain 175 238 1.0E-10 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 Gene3D G3DSA:3.30.450.20 45 123 2.0E-5 T 09-03-2017 L21SP3_RS11600 1643b45b387f6d35702e2f6f57f0ab12 589 SMART SM00387 477 589 2.6E-34 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS00580 6f8c142d1058b2c1c53e997805de79b7 109 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 9 107 15.244 T 09-03-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 L21SP3_RS00580 6f8c142d1058b2c1c53e997805de79b7 109 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 9 106 5.2E-22 T 09-03-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 L21SP3_RS00580 6f8c142d1058b2c1c53e997805de79b7 109 Gene3D G3DSA:3.30.70.240 8 84 1.8E-4 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS00580 6f8c142d1058b2c1c53e997805de79b7 109 Pfam PF09827 CRISPR associated protein Cas2 9 88 2.0E-20 T 09-03-2017 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 L21SP3_RS00580 6f8c142d1058b2c1c53e997805de79b7 109 SUPERFAMILY SSF143430 8 91 4.45E-17 T 09-03-2017 L21SP3_RS05755 c5b847355fd87836b100bd8f82b7860b 281 Gene3D G3DSA:3.90.1010.10 4 125 9.8E-46 T 09-03-2017 L21SP3_RS05755 c5b847355fd87836b100bd8f82b7860b 281 Pfam PF04324 BFD-like [2Fe-2S] binding domain 134 184 1.9E-16 T 09-03-2017 IPR007419 BFD-like [2Fe-2S]-binding domain L21SP3_RS05755 c5b847355fd87836b100bd8f82b7860b 281 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 218 279 2.0E-5 T 09-03-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 L21SP3_RS05755 c5b847355fd87836b100bd8f82b7860b 281 SUPERFAMILY SSF117916 198 279 3.71E-20 T 09-03-2017 L21SP3_RS05755 c5b847355fd87836b100bd8f82b7860b 281 Pfam PF01106 NifU-like domain 212 277 1.3E-20 T 09-03-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 L21SP3_RS05755 c5b847355fd87836b100bd8f82b7860b 281 TIGRFAM TIGR02000 NifU_proper: Fe-S cluster assembly protein NifU 1 277 1.5E-112 T 09-03-2017 IPR010238 NIF system FeS cluster assembly, NifU GO:0005506|GO:0016226|GO:0051536 L21SP3_RS05755 c5b847355fd87836b100bd8f82b7860b 281 PIRSF PIRSF000375 1 281 3.7E-116 T 09-03-2017 IPR016217 Nitrogen fixation, NifU L21SP3_RS05755 c5b847355fd87836b100bd8f82b7860b 281 Pfam PF01592 NifU-like N terminal domain 4 122 2.1E-50 T 09-03-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 L21SP3_RS05755 c5b847355fd87836b100bd8f82b7860b 281 SUPERFAMILY SSF82649 6 128 1.05E-43 T 09-03-2017 L21SP3_RS11010 4700d981b9467d661d3876045c66c4ec 434 SUPERFAMILY SSF81606 213 416 1.33E-10 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP3_RS11010 4700d981b9467d661d3876045c66c4ec 434 Gene3D G3DSA:3.30.450.40 9 170 7.1E-29 T 09-03-2017 IPR029016 GAF domain-like L21SP3_RS11010 4700d981b9467d661d3876045c66c4ec 434 SUPERFAMILY SSF55781 27 167 1.22E-18 T 09-03-2017 IPR029016 GAF domain-like L21SP3_RS11010 4700d981b9467d661d3876045c66c4ec 434 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 226 420 3.2E-36 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP3_RS11010 4700d981b9467d661d3876045c66c4ec 434 SMART SM00331 199 420 1.2E-33 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP3_RS11010 4700d981b9467d661d3876045c66c4ec 434 SMART SM00065 26 172 4.9E-10 T 09-03-2017 IPR003018 GAF domain GO:0005515 L21SP3_RS11010 4700d981b9467d661d3876045c66c4ec 434 Pfam PF13185 GAF domain 26 162 3.6E-13 T 09-03-2017 IPR003018 GAF domain GO:0005515 L21SP3_RS02975 38d55764ec46122f9db5a5b382282153 369 Pfam PF01300 Telomere recombination 21 206 1.1E-39 T 09-03-2017 IPR006070 YrdC-like domain GO:0003725 L21SP3_RS02975 38d55764ec46122f9db5a5b382282153 369 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 9 211 4.1E-46 T 09-03-2017 IPR006070 YrdC-like domain GO:0003725 L21SP3_RS02975 38d55764ec46122f9db5a5b382282153 369 SUPERFAMILY SSF55821 12 214 1.53E-45 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain L21SP3_RS02975 38d55764ec46122f9db5a5b382282153 369 SMART SM00226 219 366 2.8E-6 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP3_RS02975 38d55764ec46122f9db5a5b382282153 369 SUPERFAMILY SSF52788 219 367 7.85E-20 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP3_RS02975 38d55764ec46122f9db5a5b382282153 369 Gene3D G3DSA:3.40.50.270 219 366 1.5E-20 T 09-03-2017 L21SP3_RS02975 38d55764ec46122f9db5a5b382282153 369 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 222 362 3.5E-13 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP3_RS02975 38d55764ec46122f9db5a5b382282153 369 Gene3D G3DSA:3.90.870.10 9 215 4.9E-53 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain L21SP3_RS04600 4f04e03b29de9f1737c7434cdfd031b4 390 Gene3D G3DSA:3.40.50.2300 218 369 9.0E-24 T 09-03-2017 L21SP3_RS04600 4f04e03b29de9f1737c7434cdfd031b4 390 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 93 8.7E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP3_RS04600 4f04e03b29de9f1737c7434cdfd031b4 390 Gene3D G3DSA:1.10.10.10 27 96 1.0E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS04600 4f04e03b29de9f1737c7434cdfd031b4 390 SUPERFAMILY SSF53822 108 371 9.23E-37 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS04600 4f04e03b29de9f1737c7434cdfd031b4 390 SMART SM00345 35 94 1.1E-12 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP3_RS04600 4f04e03b29de9f1737c7434cdfd031b4 390 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 3.5E-8 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP3_RS04600 4f04e03b29de9f1737c7434cdfd031b4 390 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 3.5E-8 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP3_RS04600 4f04e03b29de9f1737c7434cdfd031b4 390 Gene3D G3DSA:3.40.50.2300 107 217 4.8E-22 T 09-03-2017 L21SP3_RS04600 4f04e03b29de9f1737c7434cdfd031b4 390 Pfam PF13377 Periplasmic binding protein-like domain 218 385 9.3E-21 T 09-03-2017 L21SP3_RS04600 4f04e03b29de9f1737c7434cdfd031b4 390 SUPERFAMILY SSF46785 26 98 2.7E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS04970 e966ad59af585817ff2e15b4250f4f97 414 SUPERFAMILY SSF48726 355 401 6.6E-5 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS04970 e966ad59af585817ff2e15b4250f4f97 414 Gene3D G3DSA:2.60.40.10 355 399 2.8E-4 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS03930 8942316a13b4a33800f309542201ae72 637 SUPERFAMILY SSF75005 43 333 9.28E-72 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS03930 8942316a13b4a33800f309542201ae72 637 Pfam PF04616 Glycosyl hydrolases family 43 44 331 7.7E-51 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS03930 8942316a13b4a33800f309542201ae72 637 Gene3D G3DSA:2.115.10.20 24 333 1.4E-84 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS03930 8942316a13b4a33800f309542201ae72 637 SUPERFAMILY SSF49899 345 580 1.37E-15 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03930 8942316a13b4a33800f309542201ae72 637 Gene3D G3DSA:2.60.120.200 343 580 6.6E-15 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03930 8942316a13b4a33800f309542201ae72 637 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 414 580 2.2E-14 T 09-03-2017 L21SP3_RS03835 83487fe58f1bcf1222d62b036beb0d9b 474 Gene3D G3DSA:3.30.1120.10 411 472 2.1E-17 T 09-03-2017 L21SP3_RS03835 83487fe58f1bcf1222d62b036beb0d9b 474 Gene3D G3DSA:3.40.720.10 30 410 3.3E-82 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS03835 83487fe58f1bcf1222d62b036beb0d9b 474 SUPERFAMILY SSF53649 30 467 7.72E-99 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS03835 83487fe58f1bcf1222d62b036beb0d9b 474 Pfam PF00884 Sulfatase 32 366 1.2E-50 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS02680 e913980db8ebc804cc167e52ffa9f111 716 SUPERFAMILY SSF48726 356 455 2.0E-15 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS02680 e913980db8ebc804cc167e52ffa9f111 716 SMART SM00409 362 455 5.8E-7 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS02680 e913980db8ebc804cc167e52ffa9f111 716 Pfam PF07679 Immunoglobulin I-set domain 358 454 1.4E-10 T 09-03-2017 IPR013098 Immunoglobulin I-set L21SP3_RS02680 e913980db8ebc804cc167e52ffa9f111 716 Gene3D G3DSA:2.60.40.10 356 455 8.3E-18 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS02680 e913980db8ebc804cc167e52ffa9f111 716 Gene3D G3DSA:2.60.120.200 456 668 1.5E-24 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS02680 e913980db8ebc804cc167e52ffa9f111 716 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 522 663 2.7E-14 T 09-03-2017 L21SP3_RS02680 e913980db8ebc804cc167e52ffa9f111 716 SUPERFAMILY SSF49899 447 667 1.6E-23 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10785 558899d5c98e8b63893d6da996c75e23 135 SUPERFAMILY SSF48300 11 71 2.62E-11 T 09-03-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS10785 558899d5c98e8b63893d6da996c75e23 135 SUPERFAMILY SSF54736 64 134 3.84E-26 T 09-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like L21SP3_RS10785 558899d5c98e8b63893d6da996c75e23 135 Gene3D G3DSA:1.20.5.710 17 58 1.6E-7 T 09-03-2017 L21SP3_RS10785 558899d5c98e8b63893d6da996c75e23 135 Gene3D G3DSA:3.30.1390.10 63 134 9.2E-35 T 09-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like L21SP3_RS10785 558899d5c98e8b63893d6da996c75e23 135 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 9 135 22.486 T 09-03-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS10785 558899d5c98e8b63893d6da996c75e23 135 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 69 134 3.1E-31 T 09-03-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS10785 558899d5c98e8b63893d6da996c75e23 135 TIGRFAM TIGR00855 L12: ribosomal protein bL12 12 134 3.6E-40 T 09-03-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS10785 558899d5c98e8b63893d6da996c75e23 135 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 12 58 1.9E-13 T 09-03-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS10785 558899d5c98e8b63893d6da996c75e23 135 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 70 134 4.0E-19 T 09-03-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02840 67e3aab5929c512ca8db220cef00225b 407 Gene3D G3DSA:3.30.420.40 86 226 3.9E-18 T 09-03-2017 L21SP3_RS02840 67e3aab5929c512ca8db220cef00225b 407 SUPERFAMILY SSF46785 21 80 1.6E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS02840 67e3aab5929c512ca8db220cef00225b 407 Gene3D G3DSA:1.10.10.10 20 85 8.5E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS02840 67e3aab5929c512ca8db220cef00225b 407 Pfam PF13412 Winged helix-turn-helix DNA-binding 20 65 3.4E-8 T 09-03-2017 L21SP3_RS02840 67e3aab5929c512ca8db220cef00225b 407 Gene3D G3DSA:3.30.420.40 227 385 2.7E-36 T 09-03-2017 L21SP3_RS02840 67e3aab5929c512ca8db220cef00225b 407 SUPERFAMILY SSF53067 214 405 1.04E-34 T 09-03-2017 L21SP3_RS02840 67e3aab5929c512ca8db220cef00225b 407 Pfam PF00480 ROK family 92 401 1.6E-42 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 L21SP3_RS02840 67e3aab5929c512ca8db220cef00225b 407 SUPERFAMILY SSF53067 85 195 7.63E-15 T 09-03-2017 L21SP3_RS10665 c014f4759ef962c58e2de72f4a17f8e0 909 Gene3D G3DSA:2.60.120.260 709 862 1.4E-5 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10665 c014f4759ef962c58e2de72f4a17f8e0 909 Gene3D G3DSA:3.20.20.80 235 372 2.8E-5 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS10665 c014f4759ef962c58e2de72f4a17f8e0 909 SUPERFAMILY SSF51445 240 446 1.69E-6 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 Gene3D G3DSA:4.10.780.10 635 674 9.5E-18 T 09-03-2017 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 SUPERFAMILY SSF53323 423 674 1.12E-80 T 09-03-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 PIRSF PIRSF000159 1 1187 0.0 T 09-03-2017 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 17 247 4.4E-80 T 09-03-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 Gene3D G3DSA:3.40.50.920 259 422 2.7E-62 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 Gene3D G3DSA:3.40.50.970 803 1181 3.0E-131 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 SUPERFAMILY SSF52518 800 1183 7.17E-119 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 Pfam PF10371 Domain of unknown function 631 684 1.6E-24 T 09-03-2017 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 751 762 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 695 706 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 432 615 7.0E-29 T 09-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 269 351 1.0E-15 T 09-03-2017 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 Gene3D G3DSA:3.40.920.10 424 627 1.0E-79 T 09-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 Gene3D G3DSA:3.40.50.970 3 258 3.8E-110 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 SMART SM00890 628 685 2.2E-30 T 09-03-2017 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 5 1180 0.0 T 09-03-2017 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 SUPERFAMILY SSF54862 671 843 5.16E-24 T 09-03-2017 L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 SUPERFAMILY SSF52922 259 420 2.57E-46 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 Pfam PF12838 4Fe-4S dicluster domain 695 764 1.8E-10 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 SUPERFAMILY SSF52518 3 258 5.59E-77 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS02150 f4ab8107ea040ff1e6337aa001ba9455 1187 Gene3D G3DSA:3.30.70.20 677 790 1.3E-22 T 09-03-2017 L21SP3_RS10910 8b3825b03854d23c9eb632bea753cfd1 694 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 458 620 1.1E-15 T 09-03-2017 L21SP3_RS10910 8b3825b03854d23c9eb632bea753cfd1 694 Gene3D G3DSA:2.60.120.200 409 624 4.9E-24 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10910 8b3825b03854d23c9eb632bea753cfd1 694 SUPERFAMILY SSF49899 407 626 1.21E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10910 8b3825b03854d23c9eb632bea753cfd1 694 Gene3D G3DSA:3.60.21.10 206 360 2.5E-17 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS10910 8b3825b03854d23c9eb632bea753cfd1 694 Gene3D G3DSA:3.60.21.10 30 173 2.5E-17 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS10910 8b3825b03854d23c9eb632bea753cfd1 694 SUPERFAMILY SSF56300 26 354 5.69E-16 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS02290 e883fd772492c62e4e21318c253fb5e1 307 Gene3D G3DSA:3.40.50.300 102 306 6.4E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02290 e883fd772492c62e4e21318c253fb5e1 307 Gene3D G3DSA:1.20.120.140 14 90 9.4E-23 T 09-03-2017 L21SP3_RS02290 e883fd772492c62e4e21318c253fb5e1 307 SMART SM00963 11 92 6.1E-14 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 L21SP3_RS02290 e883fd772492c62e4e21318c253fb5e1 307 SMART SM00382 105 283 7.3E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS02290 e883fd772492c62e4e21318c253fb5e1 307 SUPERFAMILY SSF47364 10 86 2.49E-18 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 L21SP3_RS02290 e883fd772492c62e4e21318c253fb5e1 307 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 35 307 59.754 T 09-03-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 L21SP3_RS02290 e883fd772492c62e4e21318c253fb5e1 307 SMART SM00962 106 307 1.1E-111 T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 L21SP3_RS02290 e883fd772492c62e4e21318c253fb5e1 307 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 35 306 4.8E-106 T 09-03-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 L21SP3_RS02290 e883fd772492c62e4e21318c253fb5e1 307 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 280 293 - T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 L21SP3_RS02290 e883fd772492c62e4e21318c253fb5e1 307 SUPERFAMILY SSF52540 105 306 1.28E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02290 e883fd772492c62e4e21318c253fb5e1 307 Pfam PF02881 SRP54-type protein, helical bundle domain 23 87 3.1E-12 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 L21SP3_RS02290 e883fd772492c62e4e21318c253fb5e1 307 Pfam PF00448 SRP54-type protein, GTPase domain 106 306 1.5E-75 T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 L21SP3_RS05545 5690bf9460c982b741a240c92ad3c04f 368 SUPERFAMILY SSF51445 10 362 2.78E-74 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS05545 5690bf9460c982b741a240c92ad3c04f 368 Gene3D G3DSA:3.20.20.80 13 361 2.3E-115 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS05545 5690bf9460c982b741a240c92ad3c04f 368 Pfam PF07745 Glycosyl hydrolase family 53 31 362 3.5E-94 T 09-03-2017 IPR011683 Glycosyl hydrolase family 53 GO:0015926 L21SP3_RS04810 a872d98ab7b55a82478e1066efd4a1e3 192 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 93 107 0.024 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS04810 a872d98ab7b55a82478e1066efd4a1e3 192 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 134 168 2.0E-9 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS04810 a872d98ab7b55a82478e1066efd4a1e3 192 SUPERFAMILY SSF51161 71 185 4.06E-30 T 09-03-2017 IPR011004 Trimeric LpxA-like L21SP3_RS04810 a872d98ab7b55a82478e1066efd4a1e3 192 Gene3D G3DSA:2.160.10.10 61 188 2.3E-33 T 09-03-2017 L21SP3_RS10895 83761fc9e6df8ac53cb38eb0f1a66010 707 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 490 648 8.5E-18 T 09-03-2017 L21SP3_RS10895 83761fc9e6df8ac53cb38eb0f1a66010 707 SUPERFAMILY SSF49899 429 651 7.92E-21 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10895 83761fc9e6df8ac53cb38eb0f1a66010 707 Gene3D G3DSA:2.60.40.10 340 418 3.0E-6 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS10895 83761fc9e6df8ac53cb38eb0f1a66010 707 Pfam PF00047 Immunoglobulin domain 370 416 7.7E-5 T 09-03-2017 IPR013151 Immunoglobulin L21SP3_RS10895 83761fc9e6df8ac53cb38eb0f1a66010 707 Gene3D G3DSA:2.60.120.200 478 649 3.6E-20 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10895 83761fc9e6df8ac53cb38eb0f1a66010 707 SUPERFAMILY SSF48726 351 423 8.99E-7 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS10085 6245bea735c825e1cb403dfcc52067c0 108 Gene3D G3DSA:1.10.10.10 6 96 5.1E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS10085 6245bea735c825e1cb403dfcc52067c0 108 SMART SM00418 14 95 3.1E-22 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP3_RS10085 6245bea735c825e1cb403dfcc52067c0 108 Pfam PF01022 Bacterial regulatory protein, arsR family 21 67 3.4E-14 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP3_RS10085 6245bea735c825e1cb403dfcc52067c0 108 SUPERFAMILY SSF46785 13 105 6.57E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS10085 6245bea735c825e1cb403dfcc52067c0 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 3.2E-12 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP3_RS10085 6245bea735c825e1cb403dfcc52067c0 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 46 3.2E-12 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP3_RS10085 6245bea735c825e1cb403dfcc52067c0 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 3.2E-12 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP3_RS10085 6245bea735c825e1cb403dfcc52067c0 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 3.2E-12 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 SMART SM00382 366 511 1.9E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 SUPERFAMILY SSF52540 331 602 1.61E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 370 506 1.2E-21 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 SUPERFAMILY SSF54211 613 788 3.75E-51 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 Hamap MF_01973 Lon protease [lon]. 28 790 65.295 T 09-03-2017 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 SMART SM00464 27 220 4.4E-52 T 09-03-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 27 216 2.5E-36 T 09-03-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 TIGRFAM TIGR00763 lon: endopeptidase La 30 789 5.8E-286 T 09-03-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 PIRSF PIRSF001174 16 791 2.5E-297 T 09-03-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 SUPERFAMILY SSF88697 27 215 6.96E-37 T 09-03-2017 IPR015947 PUA-like domain L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 374 393 2.5E-49 T 09-03-2017 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 691 710 2.5E-49 T 09-03-2017 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 744 762 2.5E-49 T 09-03-2017 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 721 740 2.5E-49 T 09-03-2017 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 613 629 2.5E-49 T 09-03-2017 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 Gene3D G3DSA:3.30.230.10 607 789 7.8E-67 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 Gene3D G3DSA:1.10.8.60 519 602 1.6E-29 T 09-03-2017 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 589 787 7.1E-80 T 09-03-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 L21SP3_RS03240 d28634e71d093ebe6527bb8da4f67b4e 791 Gene3D G3DSA:3.40.50.300 322 518 1.8E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 62 232 8.3E-42 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 PRINTS PR00132 Glycosyl hydrolase family 2 signature 361 375 5.0E-35 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 PRINTS PR00132 Glycosyl hydrolase family 2 signature 392 410 5.0E-35 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 PRINTS PR00132 Glycosyl hydrolase family 2 signature 466 481 5.0E-35 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 PRINTS PR00132 Glycosyl hydrolase family 2 signature 540 555 5.0E-35 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 PRINTS PR00132 Glycosyl hydrolase family 2 signature 160 175 5.0E-35 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 Gene3D G3DSA:2.60.40.320 641 740 5.5E-31 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 SUPERFAMILY SSF74650 749 1038 2.09E-83 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 Pfam PF00703 Glycosyl hydrolases family 2 234 350 6.9E-18 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 466 480 - T 09-03-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 SUPERFAMILY SSF49303 234 350 5.76E-26 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 402 427 - T 09-03-2017 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 SUPERFAMILY SSF51445 352 634 3.92E-93 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 SUPERFAMILY SSF49303 630 739 1.44E-28 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 Pfam PF16353 Domain of unknown function(DUF4981) 648 737 8.9E-27 T 09-03-2017 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 Pfam PF02929 Beta galactosidase small chain 765 1036 5.1E-79 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 352 637 1.3E-101 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 SMART SM01038 763 1037 9.2E-114 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 Gene3D G3DSA:2.70.98.10 749 1039 7.1E-94 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 Gene3D G3DSA:2.60.120.260 18 221 7.2E-78 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 Gene3D G3DSA:3.20.20.80 352 631 4.9E-106 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 Gene3D G3DSA:2.60.40.320 222 350 4.3E-31 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS04170 36deeaf3eea70c5969e20044c2899968 1053 SUPERFAMILY SSF49785 20 233 9.84E-62 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS03320 3418dc03fbb54d3bc820dee45440824c 765 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 5 747 2.4E-243 T 09-03-2017 IPR005887 Alpha-1,2-mannosidase, putative L21SP3_RS03320 3418dc03fbb54d3bc820dee45440824c 765 Gene3D G3DSA:2.70.98.10 27 326 1.1E-105 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS03320 3418dc03fbb54d3bc820dee45440824c 765 Gene3D G3DSA:1.20.1610.10 449 607 8.9E-63 T 09-03-2017 L21SP3_RS03320 3418dc03fbb54d3bc820dee45440824c 765 SUPERFAMILY SSF48208 269 738 2.38E-36 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS03320 3418dc03fbb54d3bc820dee45440824c 765 Pfam PF07971 Glycosyl hydrolase family 92 242 742 8.7E-171 T 09-03-2017 IPR012939 Glycosyl hydrolase family 92 L21SP3_RS03320 3418dc03fbb54d3bc820dee45440824c 765 Gene3D G3DSA:3.30.2080.10 608 753 1.6E-69 T 09-03-2017 L21SP3_RS03320 3418dc03fbb54d3bc820dee45440824c 765 Gene3D G3DSA:1.20.1050.60 353 442 1.3E-32 T 09-03-2017 L21SP3_RS07280 432f7196857b2c983145118a2ab73b06 282 Gene3D G3DSA:3.30.70.120 211 281 6.2E-27 T 09-03-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal L21SP3_RS07280 432f7196857b2c983145118a2ab73b06 282 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 09-03-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 L21SP3_RS07280 432f7196857b2c983145118a2ab73b06 282 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 191 281 6.4E-29 T 09-03-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 L21SP3_RS07280 432f7196857b2c983145118a2ab73b06 282 SUPERFAMILY SSF54913 210 281 3.34E-21 T 09-03-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta L21SP3_RS07280 432f7196857b2c983145118a2ab73b06 282 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 282 31.913 T 09-03-2017 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 L21SP3_RS07280 432f7196857b2c983145118a2ab73b06 282 SUPERFAMILY SSF53850 1 207 2.65E-60 T 09-03-2017 L21SP3_RS07280 432f7196857b2c983145118a2ab73b06 282 Gene3D G3DSA:3.40.190.10 107 173 2.3E-27 T 09-03-2017 L21SP3_RS07280 432f7196857b2c983145118a2ab73b06 282 Pfam PF01634 ATP phosphoribosyltransferase 49 203 2.2E-41 T 09-03-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 L21SP3_RS07280 432f7196857b2c983145118a2ab73b06 282 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 183 1.7E-55 T 09-03-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 L21SP3_RS07280 432f7196857b2c983145118a2ab73b06 282 Pfam PF08029 HisG, C-terminal domain 207 278 4.5E-25 T 09-03-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 L21SP3_RS07280 432f7196857b2c983145118a2ab73b06 282 Gene3D G3DSA:3.40.190.10 1 106 5.0E-34 T 09-03-2017 L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 SUPERFAMILY SSF103263 181 523 2.62E-134 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 SUPERFAMILY SSF52540 1 160 1.28E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 Pfam PF01264 Chorismate synthase 188 519 4.6E-139 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 Hamap MF_00109 Shikimate kinase [aroK]. 1 177 16.033 T 09-03-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 TIGRFAM TIGR00033 aroC: chorismate synthase 188 519 2.0E-131 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 Gene3D G3DSA:3.60.150.10 187 521 6.4E-148 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 PRINTS PR01100 Shikimate kinase family signature 100 117 4.8E-9 T 09-03-2017 L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 PRINTS PR01100 Shikimate kinase family signature 3 18 4.8E-9 T 09-03-2017 L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 PRINTS PR01100 Shikimate kinase family signature 27 40 4.8E-9 T 09-03-2017 L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 PRINTS PR01100 Shikimate kinase family signature 79 88 4.8E-9 T 09-03-2017 L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 Hamap MF_00300 Chorismate synthase [aroC]. 187 528 37.018 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 ProSitePatterns PS00789 Chorismate synthase signature 3. 495 511 - T 09-03-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 Gene3D G3DSA:3.40.50.300 1 158 5.6E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02780 9a733ae2b27004d6ce9ec3d8d45f63be 531 Pfam PF01202 Shikimate kinase 10 159 2.2E-24 T 09-03-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 L21SP3_RS08950 c013b757b73b1bb7c57f56a02dce45a1 148 Pfam PF00334 Nucleoside diphosphate kinase 2 136 4.9E-52 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP3_RS08950 c013b757b73b1bb7c57f56a02dce45a1 148 SMART SM00562 1 138 4.0E-75 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP3_RS08950 c013b757b73b1bb7c57f56a02dce45a1 148 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 09-03-2017 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP3_RS08950 c013b757b73b1bb7c57f56a02dce45a1 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 4.7E-43 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP3_RS08950 c013b757b73b1bb7c57f56a02dce45a1 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 4.7E-43 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP3_RS08950 c013b757b73b1bb7c57f56a02dce45a1 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 4.7E-43 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP3_RS08950 c013b757b73b1bb7c57f56a02dce45a1 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 4.7E-43 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP3_RS08950 c013b757b73b1bb7c57f56a02dce45a1 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 4.7E-43 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP3_RS08950 c013b757b73b1bb7c57f56a02dce45a1 148 Gene3D G3DSA:3.30.70.141 1 147 4.0E-57 T 09-03-2017 L21SP3_RS08950 c013b757b73b1bb7c57f56a02dce45a1 148 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 33.187 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP3_RS08950 c013b757b73b1bb7c57f56a02dce45a1 148 SUPERFAMILY SSF54919 1 146 4.06E-55 T 09-03-2017 L21SP3_RS06055 fdf81a023a50915bfc70680f699300b5 493 Pfam PF00884 Sulfatase 47 324 3.0E-40 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS06055 fdf81a023a50915bfc70680f699300b5 493 Gene3D G3DSA:3.30.1120.10 416 464 2.0E-15 T 09-03-2017 L21SP3_RS06055 fdf81a023a50915bfc70680f699300b5 493 Gene3D G3DSA:3.30.1120.10 364 378 2.0E-15 T 09-03-2017 L21SP3_RS06055 fdf81a023a50915bfc70680f699300b5 493 Gene3D G3DSA:3.40.720.10 45 184 1.1E-33 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS06055 fdf81a023a50915bfc70680f699300b5 493 ProSitePatterns PS00523 Sulfatases signature 1. 92 104 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS06055 fdf81a023a50915bfc70680f699300b5 493 SUPERFAMILY SSF53649 414 461 1.74E-87 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS06055 fdf81a023a50915bfc70680f699300b5 493 SUPERFAMILY SSF53649 46 376 1.74E-87 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS06055 fdf81a023a50915bfc70680f699300b5 493 Gene3D G3DSA:3.40.720.10 187 363 1.0E-28 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS07145 89a22be569b59040332ee2a5b1318e5f 507 Pfam PF01487 Type I 3-dehydroquinase 6 224 2.4E-38 T 09-03-2017 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 L21SP3_RS07145 89a22be569b59040332ee2a5b1318e5f 507 SUPERFAMILY SSF51569 3 226 1.39E-40 T 09-03-2017 L21SP3_RS07145 89a22be569b59040332ee2a5b1318e5f 507 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 235 505 2.8E-63 T 09-03-2017 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 L21SP3_RS07145 89a22be569b59040332ee2a5b1318e5f 507 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 233 503 28.213 T 09-03-2017 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 L21SP3_RS07145 89a22be569b59040332ee2a5b1318e5f 507 SUPERFAMILY SSF51735 339 503 2.29E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS07145 89a22be569b59040332ee2a5b1318e5f 507 Gene3D G3DSA:3.40.192.10 229 343 8.2E-26 T 09-03-2017 L21SP3_RS07145 89a22be569b59040332ee2a5b1318e5f 507 Gene3D G3DSA:3.40.50.720 344 506 7.0E-49 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS07145 89a22be569b59040332ee2a5b1318e5f 507 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 238 328 3.1E-18 T 09-03-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 L21SP3_RS07145 89a22be569b59040332ee2a5b1318e5f 507 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 349 403 2.0E-9 T 09-03-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase L21SP3_RS07145 89a22be569b59040332ee2a5b1318e5f 507 Gene3D G3DSA:3.20.20.70 4 226 6.8E-48 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS07145 89a22be569b59040332ee2a5b1318e5f 507 SUPERFAMILY SSF53223 228 338 1.09E-17 T 09-03-2017 L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 Gene3D G3DSA:1.10.8.60 300 364 9.3E-20 T 09-03-2017 L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 Gene3D G3DSA:1.10.1750.10 372 466 2.6E-34 T 09-03-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 34 467 27.588 T 09-03-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 Gene3D G3DSA:3.40.50.300 127 296 6.5E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 SMART SM00382 165 296 2.0E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 SUPERFAMILY SSF48295 373 466 2.46E-30 T 09-03-2017 IPR010921 Trp repressor/replication initiator GO:0043565 L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 47 465 5.8E-139 T 09-03-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 SUPERFAMILY SSF52540 133 343 2.02E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 Pfam PF00308 Bacterial dnaA protein 133 348 1.3E-82 T 09-03-2017 IPR013317 Chromosomal replication initiator protein DnaA L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 SMART SM00760 376 445 2.5E-32 T 09-03-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 230 244 5.8E-43 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 426 445 5.8E-43 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 198 212 5.8E-43 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 264 291 5.8E-43 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 166 186 5.8E-43 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 ProSitePatterns PS01008 DnaA protein signature. 426 445 - T 09-03-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 L21SP3_RS00350 40904331db21a82285f1d11f2fb8a147 471 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 379 445 1.4E-28 T 09-03-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 L21SP3_RS06385 aa67921346f412d946127da2cc587c43 377 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 19 361 2.4E-131 T 09-03-2017 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 L21SP3_RS06385 aa67921346f412d946127da2cc587c43 377 Gene3D G3DSA:3.40.50.300 118 361 9.2E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06385 aa67921346f412d946127da2cc587c43 377 SUPERFAMILY SSF52540 17 353 5.2E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06385 aa67921346f412d946127da2cc587c43 377 Pfam PF00437 Type II/IV secretion system protein 137 282 2.4E-42 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS06385 aa67921346f412d946127da2cc587c43 377 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 209 223 - T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS06385 aa67921346f412d946127da2cc587c43 377 SMART SM00382 138 263 9.3E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS03125 8e3c5c149d1947dea12ca52fb41de94d 514 Gene3D G3DSA:3.30.1340.10 330 378 5.9E-4 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like L21SP3_RS03765 3b45512f686f895e39a81129bd0eeeda 174 SUPERFAMILY SSF88659 108 168 5.05E-10 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03765 3b45512f686f895e39a81129bd0eeeda 174 SUPERFAMILY SSF88946 4 94 3.66E-16 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03765 3b45512f686f895e39a81129bd0eeeda 174 Pfam PF08281 Sigma-70, region 4 107 149 6.7E-8 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03765 3b45512f686f895e39a81129bd0eeeda 174 Gene3D G3DSA:1.10.1740.10 5 102 5.0E-18 T 09-03-2017 L21SP3_RS03765 3b45512f686f895e39a81129bd0eeeda 174 Gene3D G3DSA:1.10.10.10 103 154 8.8E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS03765 3b45512f686f895e39a81129bd0eeeda 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 155 3.2E-23 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03765 3b45512f686f895e39a81129bd0eeeda 174 Pfam PF04542 Sigma-70 region 2 11 78 6.9E-12 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03765 3b45512f686f895e39a81129bd0eeeda 174 TIGRFAM TIGR02989 Sig-70_gvs1: RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family 7 163 1.3E-39 T 09-03-2017 IPR014331 RNA polymerase sigma-70 ECF-like, Rhodopirellula baltica L21SP3_RS05275 8aebe25f0541144144e14c40267bd6db 58 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS05275 8aebe25f0541144144e14c40267bd6db 58 Pfam PF12838 4Fe-4S dicluster domain 9 54 3.7E-13 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS05275 8aebe25f0541144144e14c40267bd6db 58 SUPERFAMILY SSF54862 3 57 3.7E-22 T 09-03-2017 L21SP3_RS05275 8aebe25f0541144144e14c40267bd6db 58 Gene3D G3DSA:3.30.70.20 4 58 4.8E-21 T 09-03-2017 L21SP3_RS05275 8aebe25f0541144144e14c40267bd6db 58 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 3.2E-5 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 L21SP3_RS05275 8aebe25f0541144144e14c40267bd6db 58 PRINTS PR00352 3Fe-4S ferredoxin signature 43 55 3.2E-5 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 L21SP3_RS05275 8aebe25f0541144144e14c40267bd6db 58 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 3.2E-5 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 L21SP3_RS05275 8aebe25f0541144144e14c40267bd6db 58 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS04105 685eeb626fa5fa508854f27d3a691c6b 652 Gene3D G3DSA:3.30.565.10 9 208 2.8E-68 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS04105 685eeb626fa5fa508854f27d3a691c6b 652 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 8 647 24.934 T 09-03-2017 IPR020667 DNA mismatch repair protein, MutL GO:0006298 L21SP3_RS04105 685eeb626fa5fa508854f27d3a691c6b 652 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 134 2.2E-13 T 09-03-2017 L21SP3_RS04105 685eeb626fa5fa508854f27d3a691c6b 652 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 100 106 - T 09-03-2017 IPR014762 DNA mismatch repair, conserved site L21SP3_RS04105 685eeb626fa5fa508854f27d3a691c6b 652 SUPERFAMILY SSF54211 197 332 1.02E-31 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS04105 685eeb626fa5fa508854f27d3a691c6b 652 SMART SM00853 461 607 3.2E-38 T 09-03-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 L21SP3_RS04105 685eeb626fa5fa508854f27d3a691c6b 652 Gene3D G3DSA:3.30.230.10 209 332 2.0E-33 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP3_RS04105 685eeb626fa5fa508854f27d3a691c6b 652 SMART SM01340 215 333 3.2E-45 T 09-03-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 L21SP3_RS04105 685eeb626fa5fa508854f27d3a691c6b 652 Pfam PF08676 MutL C terminal dimerisation domain 463 607 2.6E-34 T 09-03-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 L21SP3_RS04105 685eeb626fa5fa508854f27d3a691c6b 652 SUPERFAMILY SSF55874 8 218 5.11E-50 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS04105 685eeb626fa5fa508854f27d3a691c6b 652 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 9 313 5.9E-88 T 09-03-2017 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 L21SP3_RS04105 685eeb626fa5fa508854f27d3a691c6b 652 SUPERFAMILY SSF118116 459 649 3.4E-44 T 09-03-2017 L21SP3_RS04105 685eeb626fa5fa508854f27d3a691c6b 652 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 217 332 3.6E-32 T 09-03-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 L21SP3_RS05660 158e7702c551e226f8cc567b60bb6d6d 133 Gene3D G3DSA:1.10.10.10 1 132 1.7E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS05660 158e7702c551e226f8cc567b60bb6d6d 133 Pfam PF02082 Transcriptional regulator 1 84 9.5E-21 T 09-03-2017 IPR000944 Transcription regulator Rrf2-type L21SP3_RS05660 158e7702c551e226f8cc567b60bb6d6d 133 SUPERFAMILY SSF46785 2 131 4.5E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS05660 158e7702c551e226f8cc567b60bb6d6d 133 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 5.1E-26 T 09-03-2017 IPR000944 Transcription regulator Rrf2-type L21SP3_RS02870 f620b03fb23cc8653bbf1d2a6f480f47 406 Pfam PF14294 Domain of unknown function (DUF4372) 7 73 1.4E-14 T 09-03-2017 IPR025399 Domain of unknown function DUF4372 L21SP3_RS02870 f620b03fb23cc8653bbf1d2a6f480f47 406 SUPERFAMILY SSF53098 128 370 1.67E-24 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS02870 f620b03fb23cc8653bbf1d2a6f480f47 406 Pfam PF01609 Transposase DDE domain 131 346 9.7E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS02870 f620b03fb23cc8653bbf1d2a6f480f47 406 Gene3D G3DSA:3.90.350.10 255 322 2.9E-4 T 09-03-2017 IPR014736 Transposase, Tn5-like, core L21SP3_RS05910 d95cdabfb91825a300bfd9ec0b7df281 471 ProSitePatterns PS00149 Sulfatases signature 2. 129 139 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS05910 d95cdabfb91825a300bfd9ec0b7df281 471 Gene3D G3DSA:3.40.720.10 27 382 4.4E-111 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS05910 d95cdabfb91825a300bfd9ec0b7df281 471 SUPERFAMILY SSF53649 28 439 1.74E-123 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS05910 d95cdabfb91825a300bfd9ec0b7df281 471 Gene3D G3DSA:3.30.1120.10 383 443 2.3E-20 T 09-03-2017 L21SP3_RS05910 d95cdabfb91825a300bfd9ec0b7df281 471 Pfam PF00884 Sulfatase 29 344 1.5E-74 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS05910 d95cdabfb91825a300bfd9ec0b7df281 471 ProSitePatterns PS00523 Sulfatases signature 1. 75 87 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS05025 91540af8007d38a65d668051e1c392d7 132 Pfam PF13581 Histidine kinase-like ATPase domain 24 129 3.0E-29 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS05025 91540af8007d38a65d668051e1c392d7 132 Gene3D G3DSA:3.30.565.10 32 127 5.0E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS05025 91540af8007d38a65d668051e1c392d7 132 SUPERFAMILY SSF55874 27 121 9.04E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS00925 33dcbc94b84160a56b65e6181886868c 321 Gene3D G3DSA:3.90.550.10 11 228 5.6E-49 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS00925 33dcbc94b84160a56b65e6181886868c 321 SUPERFAMILY SSF53448 11 221 3.64E-51 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS00925 33dcbc94b84160a56b65e6181886868c 321 Pfam PF00535 Glycosyl transferase family 2 12 119 7.8E-32 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 L21SP3_RS06610 0d8ead2b01313db1b40ef945f71a55a2 890 Gene3D G3DSA:2.60.120.200 653 846 1.3E-20 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS06610 0d8ead2b01313db1b40ef945f71a55a2 890 SUPERFAMILY SSF49785 445 605 4.34E-5 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS06610 0d8ead2b01313db1b40ef945f71a55a2 890 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 709 842 4.7E-12 T 09-03-2017 L21SP3_RS06610 0d8ead2b01313db1b40ef945f71a55a2 890 SUPERFAMILY SSF49899 642 847 8.93E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 SMART SM00823 Phosphopantetheine attachment site 1556 1625 0.21 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 SMART SM00823 Phosphopantetheine attachment site 512 580 0.019 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:3.30.300.30 2484 2608 9.4E-33 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:3.30.300.30 1437 1561 2.0E-32 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:3.30.300.30 396 516 1.2E-31 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 SUPERFAMILY SSF52777 784 1022 2.33E-45 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF00550 Phosphopantetheine attachment site 1558 1619 1.3E-10 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF00550 Phosphopantetheine attachment site 514 577 7.4E-15 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF00550 Phosphopantetheine attachment site 2605 2667 4.5E-5 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 SUPERFAMILY SSF56801 2 524 1.01E-121 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:3.40.50.1820 2677 2798 5.6E-39 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:3.40.50.1820 2875 2937 5.6E-39 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 SUPERFAMILY SSF52777 599 778 3.78E-25 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 30 424 1.1E-112 T 09-03-2017 IPR010071 Amino acid adenylation domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1074 1465 1.7E-108 T 09-03-2017 IPR010071 Amino acid adenylation domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2117 2512 7.0E-110 T 09-03-2017 IPR010071 Amino acid adenylation domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF13745 HxxPF-repeated domain 919 1007 2.1E-22 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF13745 HxxPF-repeated domain 1960 2048 5.1E-21 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 SUPERFAMILY SSF56801 1032 1568 3.79E-120 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 SUPERFAMILY SSF47336 2596 2667 2.88E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 SUPERFAMILY SSF47336 509 577 9.42E-17 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 SUPERFAMILY SSF56801 2092 2614 1.44E-124 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 ProSitePatterns PS00455 Putative AMP-binding domain signature. 147 158 - T 09-03-2017 IPR020845 AMP-binding, conserved site L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF13193 AMP-binding enzyme C-terminal domain 2496 2571 2.3E-10 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF13193 AMP-binding enzyme C-terminal domain 1450 1524 4.9E-8 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF13193 AMP-binding enzyme C-terminal domain 408 482 9.8E-12 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF00975 Thioesterase domain 2696 2795 1.5E-18 T 09-03-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:3.40.50.980 1198 1345 4.6E-29 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:3.40.50.980 2243 2389 3.1E-28 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:3.40.50.980 154 304 3.2E-27 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF00668 Condensation domain 1639 1936 8.5E-54 T 09-03-2017 IPR001242 Condensation domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF00668 Condensation domain 595 897 1.1E-48 T 09-03-2017 IPR001242 Condensation domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 SUPERFAMILY SSF47336 1553 1619 1.83E-15 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF00501 AMP-binding enzyme 1058 1442 8.9E-75 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF00501 AMP-binding enzyme 2100 2488 7.0E-76 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Pfam PF00501 AMP-binding enzyme 9 400 1.9E-75 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:2.30.38.10 309 389 4.8E-25 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:2.30.38.10 2400 2478 8.4E-23 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:2.30.38.10 1354 1431 3.5E-25 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:3.40.50.980 2093 2242 9.8E-43 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:3.40.50.980 1047 1197 6.9E-37 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:3.40.50.980 3 153 9.0E-39 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 SUPERFAMILY SSF53474 2677 2936 1.73E-46 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2237 2248 - T 09-03-2017 IPR020845 AMP-binding, conserved site L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 SUPERFAMILY SSF52777 1824 2066 3.89E-45 T 09-03-2017 L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:1.10.1200.10 1562 1627 1.8E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:1.10.1200.10 2609 2669 1.1E-17 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 Gene3D G3DSA:1.10.1200.10 517 581 1.4E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS03660 7ea6609fd1b74447e345245e4b751973 2946 SUPERFAMILY SSF52777 1644 1818 1.89E-26 T 09-03-2017 L21SP3_RS04675 765ff2fef16b91f9d86cde1e0e0f05ec 165 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 25 1.9E-4 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS04675 765ff2fef16b91f9d86cde1e0e0f05ec 165 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 29 3.4E-5 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS04675 765ff2fef16b91f9d86cde1e0e0f05ec 165 SUPERFAMILY SSF54523 9 77 2.83E-11 T 09-03-2017 L21SP3_RS06495 5a0ea02af572261ecedf3d04b16b3989 575 Pfam PF13187 4Fe-4S dicluster domain 13 57 2.9E-6 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS06495 5a0ea02af572261ecedf3d04b16b3989 575 Gene3D G3DSA:3.40.50.1780 48 104 3.0E-23 T 09-03-2017 L21SP3_RS06495 5a0ea02af572261ecedf3d04b16b3989 575 Gene3D G3DSA:3.40.50.1780 144 255 3.0E-23 T 09-03-2017 L21SP3_RS06495 5a0ea02af572261ecedf3d04b16b3989 575 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS06495 5a0ea02af572261ecedf3d04b16b3989 575 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 80 308 1.3E-40 T 09-03-2017 IPR004108 Iron hydrogenase, large subunit, C-terminal L21SP3_RS06495 5a0ea02af572261ecedf3d04b16b3989 575 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS06495 5a0ea02af572261ecedf3d04b16b3989 575 SUPERFAMILY SSF54862 6 63 3.24E-15 T 09-03-2017 L21SP3_RS06495 5a0ea02af572261ecedf3d04b16b3989 575 Gene3D G3DSA:3.30.70.20 7 47 1.2E-10 T 09-03-2017 L21SP3_RS06495 5a0ea02af572261ecedf3d04b16b3989 575 Pfam PF04060 Putative Fe-S cluster 377 405 5.5E-8 T 09-03-2017 IPR007202 4Fe-4S domain GO:0051536 L21SP3_RS06495 5a0ea02af572261ecedf3d04b16b3989 575 SUPERFAMILY SSF53920 43 327 2.88E-50 T 09-03-2017 IPR009016 Iron hydrogenase L21SP3_RS02110 ad8959df46b4ffb6b8abf82384b2fc40 407 Pfam PF01609 Transposase DDE domain 131 346 9.8E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS02110 ad8959df46b4ffb6b8abf82384b2fc40 407 SUPERFAMILY SSF53098 128 375 1.44E-25 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS02110 ad8959df46b4ffb6b8abf82384b2fc40 407 Pfam PF14294 Domain of unknown function (DUF4372) 7 73 1.4E-14 T 09-03-2017 IPR025399 Domain of unknown function DUF4372 L21SP3_RS02110 ad8959df46b4ffb6b8abf82384b2fc40 407 Gene3D G3DSA:3.90.350.10 255 322 2.9E-4 T 09-03-2017 IPR014736 Transposase, Tn5-like, core L21SP3_RS01830 ab6610e57f532742f74c8650aef52ad9 151 Gene3D G3DSA:3.40.50.300 3 142 1.7E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01830 ab6610e57f532742f74c8650aef52ad9 151 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 7 136 3.0E-29 T 09-03-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 L21SP3_RS01830 ab6610e57f532742f74c8650aef52ad9 151 SUPERFAMILY SSF52540 16 116 1.69E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01830 ab6610e57f532742f74c8650aef52ad9 151 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 4 128 2.3E-32 T 09-03-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 L21SP3_RS11630 b23b65ccbfd3440788724d32309e043c 98 SMART SM00530 34 90 3.6E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP3_RS11630 b23b65ccbfd3440788724d32309e043c 98 Gene3D G3DSA:1.10.260.40 34 93 2.5E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS11630 b23b65ccbfd3440788724d32309e043c 98 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 35 92 8.3E-12 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP3_RS11630 b23b65ccbfd3440788724d32309e043c 98 SUPERFAMILY SSF47413 46 96 3.1E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 SMART SM00086 464 504 140.0 T 09-03-2017 IPR001610 PAC motif L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 SMART SM00086 590 632 2.4E-4 T 09-03-2017 IPR001610 PAC motif L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 Gene3D G3DSA:3.30.450.40 639 817 3.4E-13 T 09-03-2017 IPR029016 GAF domain-like L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 Gene3D G3DSA:3.30.450.20 394 516 1.5E-15 T 09-03-2017 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 515 638 8.2E-17 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 392 510 1.2E-10 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 SUPERFAMILY SSF55781 653 812 6.76E-15 T 09-03-2017 IPR029016 GAF domain-like L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 SUPERFAMILY SSF55785 526 632 4.67E-20 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 SUPERFAMILY SSF55874 905 1075 7.86E-41 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 Pfam PF00512 His Kinase A (phospho-acceptor) domain 852 915 8.3E-16 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 SMART SM00091 394 459 1.0E-5 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 SMART SM00091 516 583 1.1E-4 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 Pfam PF08447 PAS fold 539 625 9.0E-11 T 09-03-2017 IPR013655 PAS fold-3 GO:0005515 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 SUPERFAMILY SSF47384 836 916 8.24E-20 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1063 1076 6.0E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1004 1018 6.0E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1039 1057 6.0E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1022 1032 6.0E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 Gene3D G3DSA:1.10.287.130 856 912 2.9E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 SMART SM00388 851 916 2.3E-19 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 SUPERFAMILY SSF55785 390 502 4.19E-14 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 SMART SM00387 963 1079 2.1E-36 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 SMART SM00065 661 818 6.8E-8 T 09-03-2017 IPR003018 GAF domain GO:0005515 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 Pfam PF04392 ABC transporter substrate binding protein 136 333 8.4E-7 T 09-03-2017 IPR007487 ABC transporter, substrate-binding protein L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 Pfam PF01590 GAF domain 661 800 4.7E-6 T 09-03-2017 IPR003018 GAF domain GO:0005515 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 Pfam PF13426 PAS domain 404 503 2.5E-11 T 09-03-2017 IPR000014 PAS domain L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 Gene3D G3DSA:3.30.565.10 918 1076 4.2E-43 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 963 1076 8.9E-28 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 Gene3D G3DSA:3.30.450.20 517 634 1.3E-20 T 09-03-2017 L21SP3_RS01325 f2c04179151c7458aa7fce74f2c108cd 1082 Gene3D G3DSA:3.30.450.20 818 855 1.3E-20 T 09-03-2017 L21SP3_RS10040 ddbd900b0c9d40054ed4f59dafd58eb0 112 Gene3D G3DSA:2.60.120.10 1 104 2.6E-20 T 09-03-2017 IPR014710 RmlC-like jelly roll fold L21SP3_RS10040 ddbd900b0c9d40054ed4f59dafd58eb0 112 SUPERFAMILY SSF51182 9 105 1.2E-22 T 09-03-2017 IPR011051 RmlC-like cupin domain L21SP3_RS10040 ddbd900b0c9d40054ed4f59dafd58eb0 112 Pfam PF07883 Cupin domain 34 100 4.9E-15 T 09-03-2017 IPR013096 Cupin 2, conserved barrel L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 SMART SM00957 9 449 6.6E-235 T 09-03-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 Hamap MF_01382 Protein translocase subunit SecA [secA]. 8 1084 18.723 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 Pfam PF07516 SecA Wing and Scaffold domain 645 1081 4.4E-46 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 Pfam PF07517 SecA DEAD-like domain 11 448 1.8E-122 T 09-03-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 Gene3D G3DSA:3.40.50.300 464 646 5.2E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 PRINTS PR00906 SecA protein signature 120 130 4.5E-65 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 PRINTS PR00906 SecA protein signature 460 473 4.5E-65 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 PRINTS PR00906 SecA protein signature 66 90 4.5E-65 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 PRINTS PR00906 SecA protein signature 175 195 4.5E-65 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 PRINTS PR00906 SecA protein signature 386 408 4.5E-65 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 PRINTS PR00906 SecA protein signature 104 118 4.5E-65 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 PRINTS PR00906 SecA protein signature 423 440 4.5E-65 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 33 573 3.2E-209 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 SUPERFAMILY SSF52540 8 233 3.06E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 SUPERFAMILY SSF52540 415 462 3.06E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 SUPERFAMILY SSF81886 1132 1144 1.29E-30 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 SUPERFAMILY SSF81886 910 965 1.29E-30 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 SUPERFAMILY SSF81886 1009 1092 1.29E-30 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 Gene3D G3DSA:3.40.50.300 416 462 2.5E-116 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 Gene3D G3DSA:3.40.50.300 4 233 2.5E-116 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 ProSitePatterns PS01312 SecA family signature. 557 572 - T 09-03-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 Pfam PF02810 SEC-C motif 1136 1154 8.9E-10 T 09-03-2017 IPR004027 SEC-C motif L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 SUPERFAMILY SSF81767 313 415 2.09E-36 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 SUPERFAMILY SSF81886 648 773 2.88E-23 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 Gene3D G3DSA:1.10.3060.10 766 837 1.7E-29 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 Gene3D G3DSA:1.10.3060.10 1003 1082 1.7E-29 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 Gene3D G3DSA:1.10.3060.10 676 765 1.2E-11 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 Gene3D G3DSA:3.90.1440.10 301 415 2.2E-38 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 SUPERFAMILY SSF52540 464 646 4.12E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 SMART SM00958 288 405 6.9E-39 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 L21SP3_RS09250 6eac1af8a8c5df024c2091fc5b384734 1156 Pfam PF01043 SecA preprotein cross-linking domain 307 405 2.0E-30 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 Gene3D G3DSA:2.60.40.320 222 345 7.0E-23 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 Pfam PF16353 Domain of unknown function(DUF4981) 639 728 1.3E-23 T 09-03-2017 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 PRINTS PR00132 Glycosyl hydrolase family 2 signature 460 475 9.0E-30 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 PRINTS PR00132 Glycosyl hydrolase family 2 signature 532 547 9.0E-30 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 PRINTS PR00132 Glycosyl hydrolase family 2 signature 387 405 9.0E-30 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 PRINTS PR00132 Glycosyl hydrolase family 2 signature 160 175 9.0E-30 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 PRINTS PR00132 Glycosyl hydrolase family 2 signature 356 370 9.0E-30 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 347 627 1.1E-86 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 62 230 1.4E-45 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 SUPERFAMILY SSF49303 235 345 3.12E-16 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 SUPERFAMILY SSF49303 621 731 4.6E-23 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 Gene3D G3DSA:2.70.98.10 739 1030 9.8E-82 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 SUPERFAMILY SSF49785 20 232 5.47E-67 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 Pfam PF00703 Glycosyl hydrolases family 2 236 345 3.2E-11 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 Gene3D G3DSA:2.60.40.320 625 729 1.3E-25 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 Gene3D G3DSA:3.20.20.80 346 623 1.8E-89 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 460 474 - T 09-03-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 SUPERFAMILY SSF51445 347 625 9.93E-78 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 SUPERFAMILY SSF74650 740 1029 1.88E-71 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 Pfam PF02929 Beta galactosidase small chain 755 1027 6.5E-68 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 SMART SM01038 753 1028 1.5E-89 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS04165 ec963e1dca61ef20db6c60a9a8c85b45 1031 Gene3D G3DSA:2.60.120.260 18 221 7.7E-83 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS04530 bda164524a23f601fd949c41e03824f0 104 Pfam PF07508 Recombinase 41 88 5.5E-6 T 09-03-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 L21SP3_RS08280 a3a469a46c45d6467ba8a704243a6b0f 307 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 283 307 9.4E-6 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS08280 a3a469a46c45d6467ba8a704243a6b0f 307 Pfam PF07589 PEP-CTERM motif 282 304 2.3E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS06620 31d582372a7d8c8e43f114fb704d616b 170 SUPERFAMILY SSF88659 106 166 5.23E-8 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS06620 31d582372a7d8c8e43f114fb704d616b 170 Gene3D G3DSA:1.10.1740.10 6 104 5.4E-20 T 09-03-2017 L21SP3_RS06620 31d582372a7d8c8e43f114fb704d616b 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 158 2.0E-23 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS06620 31d582372a7d8c8e43f114fb704d616b 170 Gene3D G3DSA:1.10.10.10 111 156 1.0E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS06620 31d582372a7d8c8e43f114fb704d616b 170 Pfam PF13384 Homeodomain-like domain 124 156 1.2E-5 T 09-03-2017 L21SP3_RS06620 31d582372a7d8c8e43f114fb704d616b 170 Pfam PF04542 Sigma-70 region 2 16 82 1.1E-14 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS06620 31d582372a7d8c8e43f114fb704d616b 170 SUPERFAMILY SSF88946 7 96 5.81E-21 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS05835 dd6cf63c201c1f0740110c2b16c1808b 410 Gene3D G3DSA:1.20.1250.20 7 183 9.2E-30 T 09-03-2017 L21SP3_RS05835 dd6cf63c201c1f0740110c2b16c1808b 410 Pfam PF07690 Major Facilitator Superfamily 14 350 5.6E-39 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 L21SP3_RS05835 dd6cf63c201c1f0740110c2b16c1808b 410 Gene3D G3DSA:1.20.1250.20 222 384 1.4E-12 T 09-03-2017 L21SP3_RS05835 dd6cf63c201c1f0740110c2b16c1808b 410 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 3 349 2.4E-61 T 09-03-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 L21SP3_RS05835 dd6cf63c201c1f0740110c2b16c1808b 410 SUPERFAMILY SSF103473 3 384 7.06E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain L21SP3_RS03195 3c69ccd5b87443e1c09f7997d41463de 299 SUPERFAMILY SSF50494 205 273 2.06E-12 T 09-03-2017 IPR009003 Peptidase S1, PA clan L21SP3_RS03195 3c69ccd5b87443e1c09f7997d41463de 299 SUPERFAMILY SSF50494 47 162 2.06E-12 T 09-03-2017 IPR009003 Peptidase S1, PA clan L21SP3_RS03195 3c69ccd5b87443e1c09f7997d41463de 299 Pfam PF13365 Trypsin-like peptidase domain 50 195 3.2E-6 T 09-03-2017 L21SP3_RS03195 3c69ccd5b87443e1c09f7997d41463de 299 Gene3D G3DSA:2.40.10.10 51 261 3.0E-5 T 09-03-2017 L21SP3_RS06040 1bf85afb89574cd593bb81b71a058c25 506 Gene3D G3DSA:3.30.420.40 2 243 7.6E-17 T 09-03-2017 L21SP3_RS06040 1bf85afb89574cd593bb81b71a058c25 506 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 244 3.5E-15 T 09-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 L21SP3_RS06040 1bf85afb89574cd593bb81b71a058c25 506 SUPERFAMILY SSF53067 5 243 5.7E-19 T 09-03-2017 L21SP3_RS06040 1bf85afb89574cd593bb81b71a058c25 506 SUPERFAMILY SSF53067 236 314 5.4E-5 T 09-03-2017 L21SP3_RS06040 1bf85afb89574cd593bb81b71a058c25 506 SUPERFAMILY SSF53067 363 456 5.4E-5 T 09-03-2017 L21SP3_RS06040 1bf85afb89574cd593bb81b71a058c25 506 SUPERFAMILY SSF53067 7 89 5.4E-5 T 09-03-2017 L21SP3_RS08015 7f7e82df771253572b89a3fe4a96d1a2 571 Pfam PF02554 Carbon starvation protein CstA 3 350 1.4E-109 T 09-03-2017 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 L21SP3_RS08015 7f7e82df771253572b89a3fe4a96d1a2 571 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 406 526 1.7E-32 T 09-03-2017 IPR025299 CstA, C-terminal domain L21SP3_RS08625 ecf3dd0a69d10c230cb600d1edb5d439 743 SMART SM00560 605 730 8.2E-5 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS08625 ecf3dd0a69d10c230cb600d1edb5d439 743 Gene3D G3DSA:3.20.20.80 54 374 4.2E-14 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS08625 ecf3dd0a69d10c230cb600d1edb5d439 743 Gene3D G3DSA:1.10.1330.10 482 533 5.3E-4 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS08625 ecf3dd0a69d10c230cb600d1edb5d439 743 SUPERFAMILY SSF49899 538 738 2.32E-29 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS08625 ecf3dd0a69d10c230cb600d1edb5d439 743 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 605 733 3.2E-20 T 09-03-2017 L21SP3_RS08625 ecf3dd0a69d10c230cb600d1edb5d439 743 Gene3D G3DSA:2.60.120.200 540 738 6.7E-30 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS08625 ecf3dd0a69d10c230cb600d1edb5d439 743 SUPERFAMILY SSF51445 59 372 2.44E-27 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS08050 f6ce6e3a503615e64be2d41c9801590f 254 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 23 251 37.11 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 L21SP3_RS08050 f6ce6e3a503615e64be2d41c9801590f 254 Pfam PF01255 Putative undecaprenyl diphosphate synthase 30 250 4.5E-73 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 L21SP3_RS08050 f6ce6e3a503615e64be2d41c9801590f 254 SUPERFAMILY SSF64005 21 240 4.97E-77 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 L21SP3_RS08050 f6ce6e3a503615e64be2d41c9801590f 254 Gene3D G3DSA:3.40.1180.10 18 252 1.2E-87 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 L21SP3_RS08050 f6ce6e3a503615e64be2d41c9801590f 254 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 23 250 9.7E-77 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 L21SP3_RS05630 19bccd7e0ef4acf1b8db434a05906877 567 Pfam PF08305 NPCBM/NEW2 domain 453 561 4.9E-6 T 09-03-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module L21SP3_RS05630 19bccd7e0ef4acf1b8db434a05906877 567 Pfam PF04773 FecR protein 186 265 1.6E-4 T 09-03-2017 IPR006860 FecR protein L21SP3_RS05630 19bccd7e0ef4acf1b8db434a05906877 567 SUPERFAMILY SSF49785 453 562 1.15E-6 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 Gene3D G3DSA:3.30.930.10 105 418 4.4E-120 T 09-03-2017 L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 103 1.2E-19 T 09-03-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 419 36.101 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 SUPERFAMILY SSF46589 1 110 1.41E-22 T 09-03-2017 IPR010978 tRNA-binding arm GO:0000166 L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 219 395 1.3E-25 T 09-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 PIRSF PIRSF001529 1 421 3.0E-141 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 Gene3D G3DSA:1.10.287.40 1 102 2.1E-24 T 09-03-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 414 1.1E-133 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 SUPERFAMILY SSF55681 114 415 1.9E-84 T 09-03-2017 L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 PRINTS PR00981 Seryl-tRNA synthetase signature 314 327 2.4E-27 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 PRINTS PR00981 Seryl-tRNA synthetase signature 272 285 2.4E-27 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 PRINTS PR00981 Seryl-tRNA synthetase signature 349 365 2.4E-27 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 PRINTS PR00981 Seryl-tRNA synthetase signature 260 272 2.4E-27 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 L21SP3_RS09870 fa91287b2affc05148446a09dc830d90 421 PRINTS PR00981 Seryl-tRNA synthetase signature 331 347 2.4E-27 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 L21SP3_RS08290 ebbe69f038076aaacf6b749b3724f846 884 Gene3D G3DSA:3.40.50.1820 185 428 2.7E-45 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08290 ebbe69f038076aaacf6b749b3724f846 884 Pfam PF00135 Carboxylesterase family 167 309 1.3E-19 T 09-03-2017 IPR002018 Carboxylesterase, type B L21SP3_RS08290 ebbe69f038076aaacf6b749b3724f846 884 SUPERFAMILY SSF47473 27 150 4.76E-12 T 09-03-2017 IPR011992 EF-hand domain pair L21SP3_RS08290 ebbe69f038076aaacf6b749b3724f846 884 Pfam PF13202 EF hand 63 75 0.04 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS08290 ebbe69f038076aaacf6b749b3724f846 884 Pfam PF13202 EF hand 29 47 0.07 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS08290 ebbe69f038076aaacf6b749b3724f846 884 Pfam PF13202 EF hand 132 150 0.0022 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS08290 ebbe69f038076aaacf6b749b3724f846 884 ProSitePatterns PS00018 EF-hand calcium-binding domain. 138 150 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS08290 ebbe69f038076aaacf6b749b3724f846 884 SUPERFAMILY SSF53474 168 433 4.22E-41 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08290 ebbe69f038076aaacf6b749b3724f846 884 Gene3D G3DSA:1.10.238.10 26 150 6.0E-13 T 09-03-2017 IPR011992 EF-hand domain pair L21SP3_RS01430 4c482e58740429d157d352a3a40d6dbc 312 SUPERFAMILY SSF53098 1 165 1.36E-33 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS01430 4c482e58740429d157d352a3a40d6dbc 312 SUPERFAMILY SSF52113 217 306 4.58E-8 T 09-03-2017 IPR001357 BRCT domain L21SP3_RS01430 4c482e58740429d157d352a3a40d6dbc 312 SMART SM00479 2 166 1.7E-15 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III L21SP3_RS01430 4c482e58740429d157d352a3a40d6dbc 312 Pfam PF00929 Exonuclease 4 156 2.9E-14 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III L21SP3_RS01430 4c482e58740429d157d352a3a40d6dbc 312 Gene3D G3DSA:3.30.420.10 1 163 2.3E-34 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS01430 4c482e58740429d157d352a3a40d6dbc 312 Gene3D G3DSA:3.40.50.10190 219 307 3.0E-12 T 09-03-2017 IPR001357 BRCT domain L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 11 306 1.9E-96 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 272 295 4.3E-19 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 141 152 4.3E-19 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 4.3E-19 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 57 76 4.3E-19 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 Gene3D G3DSA:3.40.50.1370 153 285 2.0E-48 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 10 309 41.319 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 57 64 - T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 154 6.5E-39 T 09-03-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 160 305 2.6E-25 T 09-03-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 SUPERFAMILY SSF53671 8 306 2.88E-94 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 Gene3D G3DSA:3.40.50.1370 11 152 1.5E-49 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 85 94 3.3E-32 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 223 232 3.3E-32 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 288 302 3.3E-32 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 140 157 3.3E-32 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 3.3E-32 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 L21SP3_RS00650 a0f67c949f87dcfe327ebe4291d730a6 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 47 69 3.3E-32 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 L21SP3_RS07900 efd85913d609eeea63261571829abd8e 217 SUPERFAMILY SSF52540 44 191 1.39E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07900 efd85913d609eeea63261571829abd8e 217 Gene3D G3DSA:3.40.50.300 43 189 7.8E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07900 efd85913d609eeea63261571829abd8e 217 SMART SM00382 50 213 2.4E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS07900 efd85913d609eeea63261571829abd8e 217 Pfam PF00005 ABC transporter 43 75 4.8E-6 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 67 311 6.2E-93 T 09-03-2017 IPR010213 Transcription termination factor NusA GO:0003723 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 SMART SM00316 102 170 5.3E-6 T 09-03-2017 IPR022967 RNA-binding domain, S1 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 SMART SM00322 271 381 0.13 T 09-03-2017 IPR004087 K Homology domain GO:0003676 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 SMART SM00322 200 263 2.0 T 09-03-2017 IPR004087 K Homology domain GO:0003676 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 Pfam PF00575 S1 RNA binding domain 102 163 1.1E-4 T 09-03-2017 IPR003029 S1 domain GO:0003676 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 Gene3D G3DSA:2.40.50.140 98 168 2.0E-21 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 Pfam PF13184 NusA-like KH domain 200 267 4.7E-25 T 09-03-2017 IPR025249 KH domain, NusA-like GO:0003723 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 384 27.232 T 09-03-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 SUPERFAMILY SSF54814 252 313 9.16E-12 T 09-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 SUPERFAMILY SSF54814 170 248 1.18E-30 T 09-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 Gene3D G3DSA:3.30.300.20 169 247 3.7E-35 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 Gene3D G3DSA:3.30.1480.10 67 92 1.3E-4 T 09-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 Gene3D G3DSA:3.30.1480.10 1 61 5.1E-11 T 09-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 Pfam PF08529 NusA N-terminal domain 4 62 4.9E-9 T 09-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 Gene3D G3DSA:3.30.300.20 251 316 1.9E-22 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 SUPERFAMILY SSF69705 1 89 1.7E-17 T 09-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 L21SP3_RS10185 3f28edfa39020476cf8b62a301b81516 419 SUPERFAMILY SSF50249 101 169 3.34E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS02135 ab4eef87c2ae4505297209df31978e72 202 Pfam PF00117 Glutamine amidotransferase class-I 4 196 4.1E-18 T 09-03-2017 IPR017926 Glutamine amidotransferase L21SP3_RS02135 ab4eef87c2ae4505297209df31978e72 202 PIRSF PIRSF000495 1 202 1.7E-62 T 09-03-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 L21SP3_RS02135 ab4eef87c2ae4505297209df31978e72 202 Gene3D G3DSA:3.40.50.880 1 201 1.8E-67 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS02135 ab4eef87c2ae4505297209df31978e72 202 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 199 31.958 T 09-03-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 L21SP3_RS02135 ab4eef87c2ae4505297209df31978e72 202 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 198 2.0E-60 T 09-03-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 L21SP3_RS02135 ab4eef87c2ae4505297209df31978e72 202 SUPERFAMILY SSF52317 2 199 1.1E-49 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS03250 f27cc348bbc416d4ea5d3bddc6e9c584 236 Gene3D G3DSA:3.40.50.10260 26 235 6.4E-70 T 09-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 L21SP3_RS03250 f27cc348bbc416d4ea5d3bddc6e9c584 236 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 29 235 8.0E-53 T 09-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 L21SP3_RS03250 f27cc348bbc416d4ea5d3bddc6e9c584 236 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 29 235 24.32 T 09-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 L21SP3_RS03250 f27cc348bbc416d4ea5d3bddc6e9c584 236 SUPERFAMILY SSF64153 27 235 1.44E-60 T 09-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 L21SP3_RS03250 f27cc348bbc416d4ea5d3bddc6e9c584 236 Pfam PF03853 YjeF-related protein N-terminus 51 216 1.7E-48 T 09-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 L21SP3_RS08530 d0b6fc9b2592b71e65c6826d770ce632 300 Gene3D G3DSA:3.40.50.1980 38 154 3.8E-23 T 09-03-2017 L21SP3_RS08530 d0b6fc9b2592b71e65c6826d770ce632 300 SUPERFAMILY SSF53807 38 296 6.67E-54 T 09-03-2017 L21SP3_RS08530 d0b6fc9b2592b71e65c6826d770ce632 300 Gene3D G3DSA:3.40.50.1980 157 296 8.0E-31 T 09-03-2017 L21SP3_RS08530 d0b6fc9b2592b71e65c6826d770ce632 300 Pfam PF01497 Periplasmic binding protein 41 272 1.2E-27 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 L21SP3_RS09075 64e1e086e17f3642fd0d54b424474d31 213 Gene3D G3DSA:1.10.10.60 7 53 7.3E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS09075 64e1e086e17f3642fd0d54b424474d31 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 2.2E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 L21SP3_RS09075 64e1e086e17f3642fd0d54b424474d31 213 SUPERFAMILY SSF46689 5 79 5.13E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS09075 64e1e086e17f3642fd0d54b424474d31 213 Gene3D G3DSA:1.10.357.10 54 205 1.2E-11 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 L21SP3_RS09075 64e1e086e17f3642fd0d54b424474d31 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 8.3E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 L21SP3_RS09075 64e1e086e17f3642fd0d54b424474d31 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 8.3E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 L21SP3_RS07150 21084d21685ea04ad13db73a663916d7 126 Gene3D G3DSA:2.30.29.50 5 101 3.6E-39 T 09-03-2017 IPR012544 Bacterial Pleckstrin homology domain L21SP3_RS07150 21084d21685ea04ad13db73a663916d7 126 SUPERFAMILY SSF50729 6 125 2.83E-41 T 09-03-2017 IPR011993 PH domain-like L21SP3_RS07150 21084d21685ea04ad13db73a663916d7 126 Pfam PF08000 Bacterial PH domain 3 123 2.8E-49 T 09-03-2017 IPR012544 Bacterial Pleckstrin homology domain L21SP3_RS07595 bcf0f44cdd45c2617a44e2edbb378bd6 208 SUPERFAMILY SSF69796 16 204 3.79E-57 T 09-03-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 L21SP3_RS07595 bcf0f44cdd45c2617a44e2edbb378bd6 208 Hamap MF_01408 Thymidylate synthase ThyX [thyX]. 14 208 23.407 T 09-03-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 L21SP3_RS07595 bcf0f44cdd45c2617a44e2edbb378bd6 208 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 17 203 3.0E-54 T 09-03-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 L21SP3_RS07595 bcf0f44cdd45c2617a44e2edbb378bd6 208 Pfam PF02511 Thymidylate synthase complementing protein 18 198 3.8E-59 T 09-03-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 L21SP3_RS06035 25a2db0d140cda219c8957cef919d338 310 SMART SM00342 219 302 2.6E-25 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS06035 25a2db0d140cda219c8957cef919d338 310 Gene3D G3DSA:1.10.10.60 202 255 1.9E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS06035 25a2db0d140cda219c8957cef919d338 310 SUPERFAMILY SSF46689 255 304 1.3E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS06035 25a2db0d140cda219c8957cef919d338 310 SUPERFAMILY SSF51215 11 173 1.7E-17 T 09-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP3_RS06035 25a2db0d140cda219c8957cef919d338 310 SUPERFAMILY SSF46689 202 249 3.12E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS06035 25a2db0d140cda219c8957cef919d338 310 Gene3D G3DSA:2.60.120.280 15 175 3.6E-21 T 09-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP3_RS06035 25a2db0d140cda219c8957cef919d338 310 Pfam PF12833 Helix-turn-helix domain 226 303 6.6E-21 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS06035 25a2db0d140cda219c8957cef919d338 310 Pfam PF02311 AraC-like ligand binding domain 57 173 1.6E-14 T 09-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP3_RS06035 25a2db0d140cda219c8957cef919d338 310 Gene3D G3DSA:1.10.10.60 256 305 3.9E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS03895 b6961f5a629a2a8e85d652ad85582209 436 PRINTS PR00688 Xylose isomerase signature 229 253 1.0E-84 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP3_RS03895 b6961f5a629a2a8e85d652ad85582209 436 PRINTS PR00688 Xylose isomerase signature 92 114 1.0E-84 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP3_RS03895 b6961f5a629a2a8e85d652ad85582209 436 PRINTS PR00688 Xylose isomerase signature 271 298 1.0E-84 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP3_RS03895 b6961f5a629a2a8e85d652ad85582209 436 PRINTS PR00688 Xylose isomerase signature 156 175 1.0E-84 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP3_RS03895 b6961f5a629a2a8e85d652ad85582209 436 PRINTS PR00688 Xylose isomerase signature 180 201 1.0E-84 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP3_RS03895 b6961f5a629a2a8e85d652ad85582209 436 PRINTS PR00688 Xylose isomerase signature 333 344 1.0E-84 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP3_RS03895 b6961f5a629a2a8e85d652ad85582209 436 PRINTS PR00688 Xylose isomerase signature 207 226 1.0E-84 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP3_RS03895 b6961f5a629a2a8e85d652ad85582209 436 PRINTS PR00688 Xylose isomerase signature 300 311 1.0E-84 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP3_RS03895 b6961f5a629a2a8e85d652ad85582209 436 PRINTS PR00688 Xylose isomerase signature 133 153 1.0E-84 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP3_RS03895 b6961f5a629a2a8e85d652ad85582209 436 Hamap MF_00455 Xylose isomerase [xylA]. 11 436 51.949 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP3_RS03895 b6961f5a629a2a8e85d652ad85582209 436 SUPERFAMILY SSF51658 4 436 9.64E-165 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP3_RS03895 b6961f5a629a2a8e85d652ad85582209 436 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 4 436 4.3E-213 T 09-03-2017 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 L21SP3_RS03895 b6961f5a629a2a8e85d652ad85582209 436 Gene3D G3DSA:3.20.20.150 3 436 1.2E-200 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 Gene3D G3DSA:3.30.310.50 377 454 2.3E-21 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 SUPERFAMILY SSF53738 162 262 4.71E-23 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 381 445 2.1E-11 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 Gene3D G3DSA:3.40.120.10 3 123 6.8E-33 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 SUPERFAMILY SSF53738 2 186 9.81E-36 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 SUPERFAMILY SSF53738 267 372 8.63E-25 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 104 113 - T 09-03-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 103 117 9.8E-19 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 179 198 9.8E-19 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 241 256 9.8E-19 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 267 373 5.7E-21 T 09-03-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 5 133 1.3E-29 T 09-03-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 163 261 3.7E-22 T 09-03-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 Gene3D G3DSA:3.40.120.10 258 376 2.5E-31 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 SUPERFAMILY SSF55957 376 456 2.49E-19 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS10595 45a1318a73045ba502652af02adab4b9 460 Gene3D G3DSA:3.40.120.10 181 257 2.3E-24 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS00055 7525d3a6b83d5ea4753229aa6c84e8f0 645 Gene3D G3DSA:3.30.1120.10 358 373 1.5E-9 T 09-03-2017 L21SP3_RS00055 7525d3a6b83d5ea4753229aa6c84e8f0 645 Gene3D G3DSA:3.30.1120.10 412 456 1.5E-9 T 09-03-2017 L21SP3_RS00055 7525d3a6b83d5ea4753229aa6c84e8f0 645 Pfam PF00884 Sulfatase 33 317 4.1E-40 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS00055 7525d3a6b83d5ea4753229aa6c84e8f0 645 Gene3D G3DSA:3.40.720.10 30 151 4.1E-29 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS00055 7525d3a6b83d5ea4753229aa6c84e8f0 645 ProSitePatterns PS00523 Sulfatases signature 1. 78 90 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS00055 7525d3a6b83d5ea4753229aa6c84e8f0 645 SUPERFAMILY SSF53649 32 371 1.16E-80 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS00055 7525d3a6b83d5ea4753229aa6c84e8f0 645 SUPERFAMILY SSF53649 410 450 1.16E-80 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS00055 7525d3a6b83d5ea4753229aa6c84e8f0 645 SUPERFAMILY SSF48371 499 600 9.05E-6 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 L21SP3_RS00055 7525d3a6b83d5ea4753229aa6c84e8f0 645 Gene3D G3DSA:3.40.720.10 156 357 5.9E-31 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS00055 7525d3a6b83d5ea4753229aa6c84e8f0 645 Gene3D G3DSA:1.25.10.10 499 603 3.5E-6 T 09-03-2017 IPR011989 Armadillo-like helical L21SP3_RS03260 8016fec08d7798a943dafafe2bdcb21f 136 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 9 135 4.2E-43 T 09-03-2017 IPR001602 Uncharacterised protein family UPF0047 L21SP3_RS03260 8016fec08d7798a943dafafe2bdcb21f 136 PIRSF PIRSF004681 1 136 7.1E-36 T 09-03-2017 IPR001602 Uncharacterised protein family UPF0047 L21SP3_RS03260 8016fec08d7798a943dafafe2bdcb21f 136 Pfam PF01894 Uncharacterised protein family UPF0047 20 130 3.6E-39 T 09-03-2017 IPR001602 Uncharacterised protein family UPF0047 L21SP3_RS03260 8016fec08d7798a943dafafe2bdcb21f 136 SUPERFAMILY SSF111038 5 132 3.01E-44 T 09-03-2017 IPR001602 Uncharacterised protein family UPF0047 L21SP3_RS03260 8016fec08d7798a943dafafe2bdcb21f 136 Gene3D G3DSA:2.60.120.460 1 131 2.0E-43 T 09-03-2017 IPR001602 Uncharacterised protein family UPF0047 L21SP3_RS11585 b607c17aa8afd0a83eb1bb4f08a006ff 164 PIRSF PIRSF001467 1 161 4.7E-27 T 09-03-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 L21SP3_RS11585 b607c17aa8afd0a83eb1bb4f08a006ff 164 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 6 157 3.9E-47 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 L21SP3_RS11585 b607c17aa8afd0a83eb1bb4f08a006ff 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 1.2E-10 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 L21SP3_RS11585 b607c17aa8afd0a83eb1bb4f08a006ff 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 119 134 1.2E-10 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 L21SP3_RS11585 b607c17aa8afd0a83eb1bb4f08a006ff 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 1.2E-10 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 L21SP3_RS11585 b607c17aa8afd0a83eb1bb4f08a006ff 164 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 09-03-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 L21SP3_RS11585 b607c17aa8afd0a83eb1bb4f08a006ff 164 Gene3D G3DSA:2.40.100.10 3 161 2.5E-53 T 09-03-2017 IPR029000 Cyclophilin-like domain L21SP3_RS11585 b607c17aa8afd0a83eb1bb4f08a006ff 164 SUPERFAMILY SSF50891 3 161 3.07E-56 T 09-03-2017 IPR029000 Cyclophilin-like domain L21SP3_RS01065 b1ebe5324514a1fe6f3d6708be75a211 379 Gene3D G3DSA:3.40.50.1820 248 379 2.7E-37 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS01065 b1ebe5324514a1fe6f3d6708be75a211 379 Gene3D G3DSA:3.40.50.1820 41 216 2.7E-37 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS01065 b1ebe5324514a1fe6f3d6708be75a211 379 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 30 379 5.0E-142 T 09-03-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 L21SP3_RS01065 b1ebe5324514a1fe6f3d6708be75a211 379 Pfam PF00561 alpha/beta hydrolase fold 59 367 6.7E-31 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 L21SP3_RS01065 b1ebe5324514a1fe6f3d6708be75a211 379 PRINTS PR00111 Alpha/beta hydrolase fold signature 161 174 6.5E-5 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 L21SP3_RS01065 b1ebe5324514a1fe6f3d6708be75a211 379 PRINTS PR00111 Alpha/beta hydrolase fold signature 175 188 6.5E-5 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 L21SP3_RS01065 b1ebe5324514a1fe6f3d6708be75a211 379 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 13 379 45.792 T 09-03-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 L21SP3_RS01065 b1ebe5324514a1fe6f3d6708be75a211 379 SUPERFAMILY SSF53474 32 379 5.03E-103 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS01065 b1ebe5324514a1fe6f3d6708be75a211 379 PIRSF PIRSF000443 9 379 4.2E-139 T 09-03-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 L21SP3_RS04585 d03a6553db7d7188ff55631fc4142c35 933 SUPERFAMILY SSF49899 703 898 1.12E-17 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04585 d03a6553db7d7188ff55631fc4142c35 933 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 787 898 6.4E-11 T 09-03-2017 L21SP3_RS04585 d03a6553db7d7188ff55631fc4142c35 933 SUPERFAMILY SSF50939 371 617 7.01E-30 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS04585 d03a6553db7d7188ff55631fc4142c35 933 Pfam PF13088 BNR repeat-like domain 459 616 1.4E-12 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS04585 d03a6553db7d7188ff55631fc4142c35 933 Gene3D G3DSA:2.60.120.200 678 897 1.6E-15 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04585 d03a6553db7d7188ff55631fc4142c35 933 Gene3D G3DSA:2.60.120.200 258 330 2.9E-4 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04585 d03a6553db7d7188ff55631fc4142c35 933 Gene3D G3DSA:2.120.10.10 378 616 9.7E-33 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS07705 b7371cb333283c1b309cb7e2b4404dbb 608 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 346 496 1.1E-12 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS07705 b7371cb333283c1b309cb7e2b4404dbb 608 Gene3D G3DSA:3.20.20.80 305 597 7.9E-54 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS07705 b7371cb333283c1b309cb7e2b4404dbb 608 SUPERFAMILY SSF49785 34 204 9.78E-46 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS07705 b7371cb333283c1b309cb7e2b4404dbb 608 SUPERFAMILY SSF51445 303 599 4.7E-65 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS07705 b7371cb333283c1b309cb7e2b4404dbb 608 Pfam PF00703 Glycosyl hydrolases family 2 248 306 3.2E-10 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS07705 b7371cb333283c1b309cb7e2b4404dbb 608 Gene3D G3DSA:2.60.40.320 193 304 5.8E-22 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS07705 b7371cb333283c1b309cb7e2b4404dbb 608 SUPERFAMILY SSF49303 207 307 1.7E-13 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS07705 b7371cb333283c1b309cb7e2b4404dbb 608 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 95 199 9.7E-18 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS07705 b7371cb333283c1b309cb7e2b4404dbb 608 Gene3D G3DSA:2.60.120.260 34 192 3.7E-52 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS03920 bca995bc81b0bc11b9210973a90df4e1 497 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 1 298 1.0E-104 T 09-03-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 L21SP3_RS03920 bca995bc81b0bc11b9210973a90df4e1 497 SUPERFAMILY SSF53743 1 321 9.68E-117 T 09-03-2017 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 L21SP3_RS03920 bca995bc81b0bc11b9210973a90df4e1 497 Hamap MF_00519 L-arabinose isomerase [araA]. 1 471 63.465 T 09-03-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 L21SP3_RS03920 bca995bc81b0bc11b9210973a90df4e1 497 Pfam PF02610 L-arabinose isomerase 6 354 7.8E-174 T 09-03-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 L21SP3_RS03920 bca995bc81b0bc11b9210973a90df4e1 497 Pfam PF11762 L-arabinose isomerase C-terminal domain 357 470 1.4E-47 T 09-03-2017 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 L21SP3_RS03920 bca995bc81b0bc11b9210973a90df4e1 497 SUPERFAMILY SSF50443 324 492 5.23E-69 T 09-03-2017 IPR004216 L-fucose/L-arabinose isomerase, C-terminal L21SP3_RS03920 bca995bc81b0bc11b9210973a90df4e1 497 PIRSF PIRSF001478 1 494 8.5E-240 T 09-03-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 L21SP3_RS07545 06ea3c70cc7d470bff5ed1dfe6f43c92 158 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 77 127 7.5E-9 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 L21SP3_RS09625 6966f6921ebc676bd6ed58eec8bd798b 42 Pfam PF08085 Entericidin EcnA/B family 21 40 1.9E-8 T 09-03-2017 IPR012556 Entericidin A/B GO:0009636|GO:0016020 L21SP3_RS07860 526528958240f5a95c4fbd0697f9ab53 534 Gene3D G3DSA:3.40.720.10 38 456 1.3E-126 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS07860 526528958240f5a95c4fbd0697f9ab53 534 SUPERFAMILY SSF53649 39 527 1.24E-144 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS07860 526528958240f5a95c4fbd0697f9ab53 534 Pfam PF00884 Sulfatase 41 429 1.8E-72 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS07860 526528958240f5a95c4fbd0697f9ab53 534 Gene3D G3DSA:3.30.1120.10 459 531 5.5E-23 T 09-03-2017 L21SP3_RS07860 526528958240f5a95c4fbd0697f9ab53 534 ProSitePatterns PS00149 Sulfatases signature 2. 144 154 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS03480 0e18c947077daa81c9b8d1564d4ae0ba 539 SUPERFAMILY SSF53448 295 513 3.94E-43 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS03480 0e18c947077daa81c9b8d1564d4ae0ba 539 Gene3D G3DSA:3.90.550.10 297 501 1.2E-32 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS03480 0e18c947077daa81c9b8d1564d4ae0ba 539 Pfam PF00535 Glycosyl transferase family 2 301 472 1.6E-30 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 L21SP3_RS03790 16e4bb3c9caddd18791ee6dd6cda2f8f 969 SUPERFAMILY SSF48208 399 665 9.35E-8 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS03790 16e4bb3c9caddd18791ee6dd6cda2f8f 969 SUPERFAMILY SSF49899 732 929 5.54E-34 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03790 16e4bb3c9caddd18791ee6dd6cda2f8f 969 SMART SM00560 790 920 0.0021 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS03790 16e4bb3c9caddd18791ee6dd6cda2f8f 969 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 789 923 2.2E-24 T 09-03-2017 L21SP3_RS03790 16e4bb3c9caddd18791ee6dd6cda2f8f 969 Gene3D G3DSA:2.60.120.200 730 929 1.8E-31 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS01575 e033dbcc06c3f88e2d1d6b0173461bb0 337 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 4 327 32.94 T 09-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 L21SP3_RS01575 e033dbcc06c3f88e2d1d6b0173461bb0 337 Gene3D G3DSA:3.40.718.10 5 330 1.1E-119 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 L21SP3_RS01575 e033dbcc06c3f88e2d1d6b0173461bb0 337 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 7 326 6.6E-115 T 09-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 L21SP3_RS01575 e033dbcc06c3f88e2d1d6b0173461bb0 337 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 39 323 2.1E-103 T 09-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 L21SP3_RS01575 e033dbcc06c3f88e2d1d6b0173461bb0 337 SUPERFAMILY SSF53659 6 328 3.48E-101 T 09-03-2017 L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 433 586 2.9E-24 T 09-03-2017 L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 Pfam PF03422 Carbohydrate binding module (family 6) 1039 1152 2.2E-14 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 Pfam PF03422 Carbohydrate binding module (family 6) 1207 1293 5.8E-6 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 SUPERFAMILY SSF49785 1007 1151 4.25E-17 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 SMART SM00606 1006 1153 3.7E-14 T 09-03-2017 IPR006584 Cellulose binding, type IV GO:0030246 L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 SMART SM00606 1162 1305 0.014 T 09-03-2017 IPR006584 Cellulose binding, type IV GO:0030246 L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 Pfam PF11790 Glycosyl hydrolase catalytic core 163 368 3.6E-38 T 09-03-2017 IPR024655 Uncharacterised protein family, glycosyl hydrolase catalytic domain L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 SUPERFAMILY SSF49899 381 592 9.28E-31 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 SUPERFAMILY SSF51445 184 369 1.69E-19 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 SUPERFAMILY SSF49785 1161 1304 1.05E-13 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 Gene3D G3DSA:2.60.120.200 380 591 2.7E-28 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 Gene3D G3DSA:2.60.20.10 55 144 1.4E-10 T 09-03-2017 L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 Gene3D G3DSA:2.60.120.260 1165 1303 6.2E-16 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 Gene3D G3DSA:2.60.120.260 606 690 3.4E-8 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 Gene3D G3DSA:2.60.120.260 1008 1153 9.1E-26 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 Gene3D G3DSA:2.60.120.260 933 999 1.3E-4 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 Gene3D G3DSA:3.20.20.80 206 358 1.0E-11 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS00810 a76b1e69e010bec318936d84eb280861 1365 SUPERFAMILY SSF49785 604 690 3.4E-5 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS07570 af0fb1c4880aa2e8913087068422ecc5 611 Pfam PF14574 Domain of unknown function (DUF4445) 190 605 5.4E-132 T 09-03-2017 IPR027980 Protein of unknown function DUF4445 L21SP3_RS07570 af0fb1c4880aa2e8913087068422ecc5 611 SUPERFAMILY SSF54292 6 95 2.75E-22 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP3_RS07570 af0fb1c4880aa2e8913087068422ecc5 611 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 85 2.8E-11 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP3_RS07570 af0fb1c4880aa2e8913087068422ecc5 611 Gene3D G3DSA:3.10.20.30 5 97 6.4E-23 T 09-03-2017 IPR012675 Beta-grasp domain L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4 160 4.4E-36 T 09-03-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 180 320 1.7E-49 T 09-03-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 6.9E-38 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 238 255 6.9E-38 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 133 153 6.9E-38 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 198 222 6.9E-38 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 57 84 6.9E-38 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 173 197 6.9E-38 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 SUPERFAMILY SSF51735 4 177 3.36E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 322 33.296 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 PIRSF PIRSF000114 1 332 2.9E-97 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 SUPERFAMILY SSF48179 180 331 2.52E-52 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 Gene3D G3DSA:1.10.1040.10 184 326 4.2E-54 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 Gene3D G3DSA:3.40.50.720 3 183 5.1E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS09530 d2e618137ecf3fb6df41c1d5de95bed4 333 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 188 209 - T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 L21SP3_RS00640 20822e350122f0e355375cae2dc57a0d 164 Pfam PF05991 YacP-like NYN domain 4 141 6.5E-13 T 09-03-2017 IPR010298 Protein of unknown function DUF901 L21SP3_RS01520 f497b1d02827b610e7d7aad6f6dd6c73 548 SUPERFAMILY SSF56801 8 543 2.35E-156 T 09-03-2017 L21SP3_RS01520 f497b1d02827b610e7d7aad6f6dd6c73 548 Gene3D G3DSA:3.30.300.30 444 546 7.4E-35 T 09-03-2017 L21SP3_RS01520 f497b1d02827b610e7d7aad6f6dd6c73 548 Gene3D G3DSA:2.30.38.10 364 438 6.2E-29 T 09-03-2017 L21SP3_RS01520 f497b1d02827b610e7d7aad6f6dd6c73 548 Pfam PF00501 AMP-binding enzyme 20 447 1.1E-111 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 L21SP3_RS01520 f497b1d02827b610e7d7aad6f6dd6c73 548 Gene3D G3DSA:3.40.50.980 212 356 9.0E-53 T 09-03-2017 L21SP3_RS01520 f497b1d02827b610e7d7aad6f6dd6c73 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 197 208 - T 09-03-2017 IPR020845 AMP-binding, conserved site L21SP3_RS01520 f497b1d02827b610e7d7aad6f6dd6c73 548 Gene3D G3DSA:3.40.50.980 10 211 1.2E-35 T 09-03-2017 L21SP3_RS01520 f497b1d02827b610e7d7aad6f6dd6c73 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 531 3.2E-18 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain L21SP3_RS09560 58a4f3c3889e691670945fe1d040f69d 304 Pfam PF07589 PEP-CTERM motif 280 302 4.1E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS09560 58a4f3c3889e691670945fe1d040f69d 304 SUPERFAMILY SSF49899 49 177 7.65E-20 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS09560 58a4f3c3889e691670945fe1d040f69d 304 SUPERFAMILY SSF49899 204 279 7.65E-20 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS09560 58a4f3c3889e691670945fe1d040f69d 304 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 281 302 4.2E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS09560 58a4f3c3889e691670945fe1d040f69d 304 Gene3D G3DSA:2.60.120.200 63 284 2.0E-12 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10885 dc9287da3227c6ad71ca307fa99f9adf 311 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 291 309 6.6E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS10885 dc9287da3227c6ad71ca307fa99f9adf 311 Pfam PF07589 PEP-CTERM motif 291 310 3.4E-6 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS02225 5d77aec1336473e2e5a353c630f6f19b 77 Pfam PF01197 Ribosomal protein L31 1 65 1.2E-32 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS02225 5d77aec1336473e2e5a353c630f6f19b 77 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 68 29.94 T 09-03-2017 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS02225 5d77aec1336473e2e5a353c630f6f19b 77 PRINTS PR01249 Ribosomal protein L31 signature 2 19 9.6E-22 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS02225 5d77aec1336473e2e5a353c630f6f19b 77 PRINTS PR01249 Ribosomal protein L31 signature 46 64 9.6E-22 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS02225 5d77aec1336473e2e5a353c630f6f19b 77 PRINTS PR01249 Ribosomal protein L31 signature 31 46 9.6E-22 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS02225 5d77aec1336473e2e5a353c630f6f19b 77 SUPERFAMILY SSF143800 1 66 5.89E-28 T 09-03-2017 L21SP3_RS02225 5d77aec1336473e2e5a353c630f6f19b 77 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 56 - T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS02225 5d77aec1336473e2e5a353c630f6f19b 77 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 66 4.6E-32 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS11025 2d254773e3ae11cf51e13f9a0fa0ef53 392 Gene3D G3DSA:2.40.40.10 203 392 1.9E-30 T 09-03-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain L21SP3_RS11025 2d254773e3ae11cf51e13f9a0fa0ef53 392 Gene3D G3DSA:2.40.40.10 91 193 3.2E-12 T 09-03-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain L21SP3_RS11025 2d254773e3ae11cf51e13f9a0fa0ef53 392 SUPERFAMILY SSF50685 44 392 3.14E-86 T 09-03-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain L21SP3_RS11025 2d254773e3ae11cf51e13f9a0fa0ef53 392 Pfam PF03562 MltA specific insert domain 63 292 1.9E-50 T 09-03-2017 IPR005300 Lytic transglycosylase MltA GO:0004553 L21SP3_RS11025 2d254773e3ae11cf51e13f9a0fa0ef53 392 SMART SM00925 144 292 4.5E-45 T 09-03-2017 IPR005300 Lytic transglycosylase MltA GO:0004553 L21SP3_RS11025 2d254773e3ae11cf51e13f9a0fa0ef53 392 Pfam PF06725 3D domain 310 389 1.0E-17 T 09-03-2017 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 L21SP3_RS11025 2d254773e3ae11cf51e13f9a0fa0ef53 392 PIRSF PIRSF019422 1 392 7.5E-103 T 09-03-2017 IPR026044 Membrane-bound lytic murein transglycosylase A L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 TIGRFAM TIGR00016 ackA: acetate kinase 1 394 8.1E-148 T 09-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 Hamap MF_00020 Acetate kinase [ackA]. 1 395 167.662 T 09-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 3 14 - T 09-03-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 Gene3D G3DSA:3.30.420.40 96 206 1.6E-10 T 09-03-2017 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 SUPERFAMILY SSF53067 160 393 2.19E-82 T 09-03-2017 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 SUPERFAMILY SSF53067 1 198 4.1E-60 T 09-03-2017 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 Gene3D G3DSA:3.30.420.40 207 393 4.9E-75 T 09-03-2017 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 Pfam PF00871 Acetokinase family 2 387 1.6E-142 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 PIRSF PIRSF000722 1 395 9.4E-143 T 09-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 Gene3D G3DSA:3.30.420.40 2 39 9.6E-4 T 09-03-2017 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 PRINTS PR00471 Acetate kinase family signature 375 387 5.8E-44 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 PRINTS PR00471 Acetate kinase family signature 323 339 5.8E-44 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 PRINTS PR00471 Acetate kinase family signature 205 226 5.8E-44 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 PRINTS PR00471 Acetate kinase family signature 3 14 5.8E-44 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 PRINTS PR00471 Acetate kinase family signature 175 188 5.8E-44 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 PRINTS PR00471 Acetate kinase family signature 301 314 5.8E-44 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 L21SP3_RS03415 10cf17736db62556b30c5726e63faac9 395 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 205 222 - T 09-03-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 L21SP3_RS06920 60c455c6202d699c44ad1ff90610fcb1 258 Pfam PF01618 MotA/TolQ/ExbB proton channel family 144 242 2.8E-26 T 09-03-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 L21SP3_RS05735 828de06e1d3c26a05f2ba955b5f19413 184 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 9 178 1.7E-47 T 09-03-2017 IPR027623 AmmeMemoRadiSam system protein A L21SP3_RS05735 828de06e1d3c26a05f2ba955b5f19413 184 SUPERFAMILY SSF143447 7 180 8.89E-49 T 09-03-2017 IPR002733 AMMECR1 domain L21SP3_RS05735 828de06e1d3c26a05f2ba955b5f19413 184 Gene3D G3DSA:3.30.700.20 2 115 1.8E-30 T 09-03-2017 IPR027485 AMMECR1, N-terminal L21SP3_RS05735 828de06e1d3c26a05f2ba955b5f19413 184 Pfam PF01871 AMMECR1 25 178 2.4E-41 T 09-03-2017 IPR002733 AMMECR1 domain L21SP3_RS05735 828de06e1d3c26a05f2ba955b5f19413 184 Gene3D G3DSA:3.30.1490.150 116 175 3.8E-26 T 09-03-2017 L21SP3_RS05735 828de06e1d3c26a05f2ba955b5f19413 184 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 34 178 4.8E-32 T 09-03-2017 IPR023473 AMMECR1 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 SUPERFAMILY SSF52172 620 735 1.57E-37 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 Pfam PF01627 Hpt domain 772 852 2.2E-9 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 SUPERFAMILY SSF47226 764 859 1.44E-18 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 SMART SM00387 474 589 6.7E-34 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 567 9.5E-18 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 573 586 9.5E-18 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 542 9.5E-18 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 528 9.5E-18 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 Pfam PF00072 Response regulator receiver domain 621 730 4.4E-28 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 26 272 9.2E-43 T 09-03-2017 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 Gene3D G3DSA:1.20.120.160 763 859 1.3E-18 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 SUPERFAMILY SSF47384 350 428 5.49E-22 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 Gene3D G3DSA:3.40.190.10 118 217 2.5E-4 T 09-03-2017 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 SUPERFAMILY SSF55874 416 587 1.96E-43 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 Gene3D G3DSA:3.40.50.2300 620 738 6.7E-41 T 09-03-2017 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 SMART SM00448 619 730 1.0E-37 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 Pfam PF00512 His Kinase A (phospho-acceptor) domain 362 427 1.1E-18 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 SUPERFAMILY SSF53850 41 218 1.86E-23 T 09-03-2017 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 475 587 8.1E-27 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 Gene3D G3DSA:1.10.287.130 354 413 2.4E-18 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 SMART SM00388 362 427 3.2E-22 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11530 f607a0d7521d5c8fdb2c0231981198e2 860 Gene3D G3DSA:3.30.565.10 414 587 3.1E-43 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS06925 74c9e75250f217ac2d435b38f5c2420e 154 Pfam PF13768 von Willebrand factor type A domain 8 146 8.6E-10 T 09-03-2017 IPR002035 von Willebrand factor, type A L21SP3_RS06925 74c9e75250f217ac2d435b38f5c2420e 154 Gene3D G3DSA:3.40.50.410 5 147 1.0E-4 T 09-03-2017 IPR002035 von Willebrand factor, type A L21SP3_RS06925 74c9e75250f217ac2d435b38f5c2420e 154 SUPERFAMILY SSF53300 5 151 2.63E-13 T 09-03-2017 IPR002035 von Willebrand factor, type A L21SP3_RS03380 2c10e0e89f583a1067939e2ea8227545 244 Gene3D G3DSA:3.30.450.20 129 231 1.7E-8 T 09-03-2017 L21SP3_RS03380 2c10e0e89f583a1067939e2ea8227545 244 Pfam PF00072 Response regulator receiver domain 4 115 3.0E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS03380 2c10e0e89f583a1067939e2ea8227545 244 SUPERFAMILY SSF52172 1 137 2.85E-39 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS03380 2c10e0e89f583a1067939e2ea8227545 244 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 130 241 7.3E-8 T 09-03-2017 IPR000014 PAS domain L21SP3_RS03380 2c10e0e89f583a1067939e2ea8227545 244 Gene3D G3DSA:3.40.50.2300 2 128 5.7E-39 T 09-03-2017 L21SP3_RS03380 2c10e0e89f583a1067939e2ea8227545 244 SMART SM00448 2 115 1.1E-36 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS03380 2c10e0e89f583a1067939e2ea8227545 244 SUPERFAMILY SSF55785 120 240 6.66E-11 T 09-03-2017 IPR000014 PAS domain L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 SUPERFAMILY SSF82714 723 808 1.57E-17 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 SUPERFAMILY SSF82866 806 1030 7.32E-57 T 09-03-2017 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 Pfam PF00873 AcrB/AcrD/AcrF family 5 1028 3.9E-292 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 Gene3D G3DSA:3.30.2090.10 186 268 6.4E-16 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 Gene3D G3DSA:3.30.2090.10 723 807 5.4E-19 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 Gene3D G3DSA:1.10.3850.10 814 1029 3.0E-60 T 09-03-2017 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 Gene3D G3DSA:1.10.3850.10 278 499 1.1E-56 T 09-03-2017 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 SUPERFAMILY SSF82714 186 268 1.19E-14 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 SUPERFAMILY SSF82693 43 130 3.66E-21 T 09-03-2017 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 SUPERFAMILY SSF82693 568 666 3.14E-9 T 09-03-2017 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 SUPERFAMILY SSF82866 294 498 1.31E-41 T 09-03-2017 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 SUPERFAMILY SSF82693 140 185 9.07E-19 T 09-03-2017 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 SUPERFAMILY SSF82693 271 327 9.07E-19 T 09-03-2017 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1029 0.0 T 09-03-2017 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 8.1E-36 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 8.1E-36 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 8.1E-36 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 8.1E-36 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 8.1E-36 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 8.1E-36 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 8.1E-36 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS10055 9d751e4b86dfd960c1af25f728c311c0 1037 Gene3D G3DSA:3.30.70.1430 43 143 1.9E-24 T 09-03-2017 L21SP3_RS08775 53fbab063d733a65371a29ece3298b3f 351 SUPERFAMILY SSF53335 245 324 5.94E-57 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08775 53fbab063d733a65371a29ece3298b3f 351 SUPERFAMILY SSF53335 2 188 5.94E-57 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08775 53fbab063d733a65371a29ece3298b3f 351 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 286 300 6.4E-14 T 09-03-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 L21SP3_RS08775 53fbab063d733a65371a29ece3298b3f 351 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 27 39 6.4E-14 T 09-03-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 L21SP3_RS08775 53fbab063d733a65371a29ece3298b3f 351 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 263 285 6.4E-14 T 09-03-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 L21SP3_RS08775 53fbab063d733a65371a29ece3298b3f 351 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 78 97 6.4E-14 T 09-03-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 L21SP3_RS08775 53fbab063d733a65371a29ece3298b3f 351 Pfam PF01555 DNA methylase 27 322 4.1E-46 T 09-03-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 L21SP3_RS08775 53fbab063d733a65371a29ece3298b3f 351 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 30 36 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 L21SP3_RS08775 53fbab063d733a65371a29ece3298b3f 351 Gene3D G3DSA:3.40.50.150 2 169 3.6E-55 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08775 53fbab063d733a65371a29ece3298b3f 351 Gene3D G3DSA:3.40.50.150 233 330 3.6E-55 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS05855 59958a447875954ce6cdc1b9405c787c 314 Gene3D G3DSA:3.30.70.20 267 312 1.4E-15 T 09-03-2017 L21SP3_RS05855 59958a447875954ce6cdc1b9405c787c 314 Pfam PF13187 4Fe-4S dicluster domain 267 311 6.4E-8 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS05855 59958a447875954ce6cdc1b9405c787c 314 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 296 307 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS05855 59958a447875954ce6cdc1b9405c787c 314 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 267 278 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS05855 59958a447875954ce6cdc1b9405c787c 314 PRINTS PR00069 Aldo-keto reductase signature 93 111 3.3E-9 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 L21SP3_RS05855 59958a447875954ce6cdc1b9405c787c 314 PRINTS PR00069 Aldo-keto reductase signature 42 66 3.3E-9 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 L21SP3_RS05855 59958a447875954ce6cdc1b9405c787c 314 PRINTS PR00069 Aldo-keto reductase signature 128 145 3.3E-9 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 L21SP3_RS05855 59958a447875954ce6cdc1b9405c787c 314 Gene3D G3DSA:3.20.20.100 1 212 1.6E-32 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain L21SP3_RS05855 59958a447875954ce6cdc1b9405c787c 314 Pfam PF00248 Aldo/keto reductase family 15 212 1.8E-22 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain L21SP3_RS05855 59958a447875954ce6cdc1b9405c787c 314 SUPERFAMILY SSF54862 259 312 1.58E-17 T 09-03-2017 L21SP3_RS05855 59958a447875954ce6cdc1b9405c787c 314 SUPERFAMILY SSF51430 3 245 2.36E-36 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain L21SP3_RS03330 747a25cc2834f62242b7efa352c86cfc 882 Pfam PF16334 Domain of unknown function (DUF4964) 37 109 4.6E-26 T 09-03-2017 IPR032515 Domain of unknown function DUF4964 L21SP3_RS03330 747a25cc2834f62242b7efa352c86cfc 882 Gene3D G3DSA:2.60.120.260 743 872 7.1E-6 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS03330 747a25cc2834f62242b7efa352c86cfc 882 Pfam PF16335 Domain of unknown function (DUF4965) 355 530 1.0E-68 T 09-03-2017 IPR032514 Domain of unknown function DUF4965 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2 L21SP3_RS03330 747a25cc2834f62242b7efa352c86cfc 882 Pfam PF17168 Domain of unknown function (DUF5127) 121 350 4.4E-56 T 09-03-2017 IPR033433 Domain of unknown function DUF5127 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2 L21SP3_RS03330 747a25cc2834f62242b7efa352c86cfc 882 SUPERFAMILY SSF49785 743 875 4.08E-7 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS03330 747a25cc2834f62242b7efa352c86cfc 882 Pfam PF08760 Domain of unknown function (DUF1793) 536 700 3.2E-58 T 09-03-2017 IPR014870 Domain of unknown function DUF1793 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2 L21SP3_RS03330 747a25cc2834f62242b7efa352c86cfc 882 SUPERFAMILY SSF48208 404 636 6.19E-14 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS06550 63d593a5bc5f346e041fd54f49c81784 327 Pfam PF01380 SIS domain 39 170 8.5E-23 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 L21SP3_RS06550 63d593a5bc5f346e041fd54f49c81784 327 Pfam PF00571 CBS domain 209 259 6.3E-4 T 09-03-2017 IPR000644 CBS domain L21SP3_RS06550 63d593a5bc5f346e041fd54f49c81784 327 Pfam PF00571 CBS domain 270 322 5.1E-7 T 09-03-2017 IPR000644 CBS domain L21SP3_RS06550 63d593a5bc5f346e041fd54f49c81784 327 Gene3D G3DSA:3.40.50.10490 6 195 6.2E-44 T 09-03-2017 L21SP3_RS06550 63d593a5bc5f346e041fd54f49c81784 327 SMART SM00116 210 259 14.0 T 09-03-2017 IPR000644 CBS domain L21SP3_RS06550 63d593a5bc5f346e041fd54f49c81784 327 SMART SM00116 277 325 4.9E-6 T 09-03-2017 IPR000644 CBS domain L21SP3_RS06550 63d593a5bc5f346e041fd54f49c81784 327 PIRSF PIRSF004692 1 326 3.9E-106 T 09-03-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 L21SP3_RS06550 63d593a5bc5f346e041fd54f49c81784 327 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 45 315 4.4E-81 T 09-03-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 L21SP3_RS06550 63d593a5bc5f346e041fd54f49c81784 327 SUPERFAMILY SSF53697 6 326 5.78E-53 T 09-03-2017 L21SP3_RS06550 63d593a5bc5f346e041fd54f49c81784 327 Gene3D G3DSA:3.10.580.10 196 321 3.9E-25 T 09-03-2017 L21SP3_RS05780 a112ce8384cbf8033b29396bab627819 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 1 19 2.1E-42 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 L21SP3_RS05780 a112ce8384cbf8033b29396bab627819 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 110 132 2.1E-42 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 L21SP3_RS05780 a112ce8384cbf8033b29396bab627819 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 19 40 2.1E-42 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 L21SP3_RS05780 a112ce8384cbf8033b29396bab627819 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 48 72 2.1E-42 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 L21SP3_RS05780 a112ce8384cbf8033b29396bab627819 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 84 100 2.1E-42 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 L21SP3_RS05780 a112ce8384cbf8033b29396bab627819 159 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 2 154 1.2E-53 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 L21SP3_RS05780 a112ce8384cbf8033b29396bab627819 159 SUPERFAMILY SSF52374 2 153 6.76E-43 T 09-03-2017 L21SP3_RS05780 a112ce8384cbf8033b29396bab627819 159 Pfam PF01467 Cytidylyltransferase-like 4 131 8.1E-22 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP3_RS05780 a112ce8384cbf8033b29396bab627819 159 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 1 156 31.887 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 L21SP3_RS05780 a112ce8384cbf8033b29396bab627819 159 Gene3D G3DSA:3.40.50.620 2 155 2.7E-49 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS05780 a112ce8384cbf8033b29396bab627819 159 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 56 4.9E-16 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP3_RS03430 a4247cf908c47b137c4163745f6f57ba 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 158 2.9E-21 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03430 a4247cf908c47b137c4163745f6f57ba 168 SUPERFAMILY SSF88946 2 91 6.67E-18 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03430 a4247cf908c47b137c4163745f6f57ba 168 Pfam PF04542 Sigma-70 region 2 16 74 8.9E-12 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03430 a4247cf908c47b137c4163745f6f57ba 168 Gene3D G3DSA:1.10.10.10 103 162 8.0E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS03430 a4247cf908c47b137c4163745f6f57ba 168 SUPERFAMILY SSF88659 105 163 1.25E-8 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03430 a4247cf908c47b137c4163745f6f57ba 168 Gene3D G3DSA:1.10.1740.10 2 97 3.5E-18 T 09-03-2017 L21SP3_RS02185 e0ed5ecf891cad74f6016c4a841161eb 253 Gene3D G3DSA:3.30.450.40 76 252 8.2E-49 T 09-03-2017 IPR029016 GAF domain-like L21SP3_RS02185 e0ed5ecf891cad74f6016c4a841161eb 253 SUPERFAMILY SSF46785 7 74 1.34E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS02185 e0ed5ecf891cad74f6016c4a841161eb 253 Pfam PF01614 Bacterial transcriptional regulator 122 246 5.1E-31 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal L21SP3_RS02185 e0ed5ecf891cad74f6016c4a841161eb 253 Gene3D G3DSA:1.10.10.10 4 75 1.5E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS02185 e0ed5ecf891cad74f6016c4a841161eb 253 SUPERFAMILY SSF55781 76 250 5.76E-45 T 09-03-2017 IPR029016 GAF domain-like L21SP3_RS02185 e0ed5ecf891cad74f6016c4a841161eb 253 Pfam PF09339 IclR helix-turn-helix domain 11 57 4.2E-9 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 L21SP3_RS02185 e0ed5ecf891cad74f6016c4a841161eb 253 SMART SM00346 6 94 9.9E-12 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 L21SP3_RS08540 a9162a82b72fff61624c252a1765fdc2 336 SUPERFAMILY SSF81345 14 335 1.05E-70 T 09-03-2017 IPR029022 ABC transporter, BtuC-like L21SP3_RS08540 a9162a82b72fff61624c252a1765fdc2 336 Gene3D G3DSA:1.10.3470.10 14 336 3.7E-84 T 09-03-2017 IPR029022 ABC transporter, BtuC-like L21SP3_RS08540 a9162a82b72fff61624c252a1765fdc2 336 Pfam PF01032 FecCD transport family 22 335 2.8E-80 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 L21SP3_RS10695 94a7ee5183a67f489ca7cfc605c366b0 651 SMART SM00560 463 600 3.5E-4 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS10695 94a7ee5183a67f489ca7cfc605c366b0 651 SMART SM00409 302 386 0.0029 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS10695 94a7ee5183a67f489ca7cfc605c366b0 651 Gene3D G3DSA:2.60.40.10 296 375 1.8E-7 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS10695 94a7ee5183a67f489ca7cfc605c366b0 651 Gene3D G3DSA:2.60.120.200 388 608 4.1E-31 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10695 94a7ee5183a67f489ca7cfc605c366b0 651 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 460 603 6.9E-24 T 09-03-2017 L21SP3_RS10695 94a7ee5183a67f489ca7cfc605c366b0 651 SUPERFAMILY SSF49899 403 608 1.58E-31 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10695 94a7ee5183a67f489ca7cfc605c366b0 651 SUPERFAMILY SSF48726 293 378 8.34E-8 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 313 4.4E-104 T 09-03-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 256 5.6E-29 T 09-03-2017 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 5.6E-29 T 09-03-2017 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 5.6E-29 T 09-03-2017 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 5.6E-29 T 09-03-2017 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 5.6E-29 T 09-03-2017 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 8.5E-61 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 204 220 8.5E-61 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 8.5E-61 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 263 8.5E-61 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 8.5E-61 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 132 144 8.5E-61 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 8.5E-61 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 8.5E-61 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 171 8.5E-61 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 Gene3D G3DSA:3.50.50.60 122 248 2.3E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 SUPERFAMILY SSF51905 7 316 4.82E-48 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 Gene3D G3DSA:3.50.50.60 249 316 2.6E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 Gene3D G3DSA:3.50.50.60 4 121 2.6E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09005 220ef34b08d155dda8f2a944a72e22d4 322 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 303 6.3E-48 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS08360 c1017cdc7adc3f1780bf0889d124a5b6 210 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 77 141 5.3E-20 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP3_RS08360 c1017cdc7adc3f1780bf0889d124a5b6 210 Gene3D G3DSA:1.10.60.10 88 149 1.6E-17 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP3_RS08360 c1017cdc7adc3f1780bf0889d124a5b6 210 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 16 72 2.0E-12 T 09-03-2017 IPR022687 DTXR-type HTH domain GO:0003677 L21SP3_RS08360 c1017cdc7adc3f1780bf0889d124a5b6 210 Gene3D G3DSA:1.10.10.10 16 87 5.6E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS08360 c1017cdc7adc3f1780bf0889d124a5b6 210 SUPERFAMILY SSF47979 77 153 1.26E-18 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP3_RS08360 c1017cdc7adc3f1780bf0889d124a5b6 210 SUPERFAMILY SSF46785 16 76 2.58E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS08360 c1017cdc7adc3f1780bf0889d124a5b6 210 SMART SM00529 38 137 8.2E-30 T 09-03-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 L21SP3_RS02395 74d97316d2943556313c502dfc10ffb9 207 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 2 206 19.21 T 09-03-2017 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS02395 74d97316d2943556313c502dfc10ffb9 207 Pfam PF01813 ATP synthase subunit D 11 199 4.7E-48 T 09-03-2017 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS02395 74d97316d2943556313c502dfc10ffb9 207 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 4 199 1.5E-41 T 09-03-2017 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS10105 424b2b048c30d813eaf68db54b9efd36 77 Pfam PF13192 Thioredoxin domain 3 76 2.9E-26 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS10105 424b2b048c30d813eaf68db54b9efd36 77 SUPERFAMILY SSF52833 1 76 2.92E-18 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS10105 424b2b048c30d813eaf68db54b9efd36 77 PIRSF PIRSF037031 1 77 3.1E-31 T 09-03-2017 IPR005243 Redox-active disulphide protein 2 L21SP3_RS10105 424b2b048c30d813eaf68db54b9efd36 77 TIGRFAM TIGR00412 redox_disulf_2: redox-active disulfide protein 2 1 76 5.7E-27 T 09-03-2017 IPR005243 Redox-active disulphide protein 2 L21SP3_RS10105 424b2b048c30d813eaf68db54b9efd36 77 Gene3D G3DSA:3.40.30.10 2 76 1.7E-28 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS08690 67214b00a38818efa89e00672dba3cbf 191 PRINTS PR01651 Protein-export SecG membrane protein signature 78 100 1.0E-9 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 L21SP3_RS08690 67214b00a38818efa89e00672dba3cbf 191 PRINTS PR01651 Protein-export SecG membrane protein signature 48 62 1.0E-9 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 L21SP3_RS08690 67214b00a38818efa89e00672dba3cbf 191 PRINTS PR01651 Protein-export SecG membrane protein signature 28 48 1.0E-9 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 L21SP3_RS08690 67214b00a38818efa89e00672dba3cbf 191 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 28 95 4.1E-16 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 L21SP3_RS08690 67214b00a38818efa89e00672dba3cbf 191 Pfam PF03840 Preprotein translocase SecG subunit 29 95 6.1E-15 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 L21SP3_RS05300 b55d96f0ee275c7c10a8be8f10111d09 339 SUPERFAMILY SSF48452 86 249 7.3E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS05300 b55d96f0ee275c7c10a8be8f10111d09 339 Gene3D G3DSA:1.25.40.10 85 261 2.2E-6 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS10035 ea99b93b6da7402dd1256e1fc9544e51 138 Gene3D G3DSA:1.10.10.10 6 135 3.0E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS10035 ea99b93b6da7402dd1256e1fc9544e51 138 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 6 132 1.1E-32 T 09-03-2017 IPR000944 Transcription regulator Rrf2-type L21SP3_RS10035 ea99b93b6da7402dd1256e1fc9544e51 138 Pfam PF02082 Transcriptional regulator 4 84 1.3E-21 T 09-03-2017 IPR000944 Transcription regulator Rrf2-type L21SP3_RS10035 ea99b93b6da7402dd1256e1fc9544e51 138 SUPERFAMILY SSF46785 6 133 1.85E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS03850 b6a90db30e9fc15af7f65404ee769996 581 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 33 578 2.2E-157 T 09-03-2017 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 L21SP3_RS03850 b6a90db30e9fc15af7f65404ee769996 581 Pfam PF02272 DHHA1 domain 390 452 4.1E-10 T 09-03-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 L21SP3_RS03850 b6a90db30e9fc15af7f65404ee769996 581 Pfam PF01368 DHH family 86 219 6.0E-12 T 09-03-2017 IPR001667 DDH domain L21SP3_RS03850 b6a90db30e9fc15af7f65404ee769996 581 SUPERFAMILY SSF64182 64 466 1.57E-109 T 09-03-2017 L21SP3_RS08535 75af94db05112e6ee7103642b74fb18e 267 Pfam PF00005 ABC transporter 22 170 9.0E-33 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS08535 75af94db05112e6ee7103642b74fb18e 267 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS08535 75af94db05112e6ee7103642b74fb18e 267 SMART SM00382 31 218 3.4E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS08535 75af94db05112e6ee7103642b74fb18e 267 Gene3D G3DSA:3.40.50.300 2 233 4.3E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08535 75af94db05112e6ee7103642b74fb18e 267 SUPERFAMILY SSF52540 5 239 2.45E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10580 c2b7766f8e6a95935b5431bd49fdbe70 217 SUPERFAMILY SSF52540 8 207 7.99E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10580 c2b7766f8e6a95935b5431bd49fdbe70 217 Pfam PF02223 Thymidylate kinase 14 183 4.0E-41 T 09-03-2017 L21SP3_RS10580 c2b7766f8e6a95935b5431bd49fdbe70 217 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 8 201 1.9E-43 T 09-03-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 L21SP3_RS10580 c2b7766f8e6a95935b5431bd49fdbe70 217 Hamap MF_00165 Thymidylate kinase [tmk]. 10 213 22.623 T 09-03-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 L21SP3_RS10580 c2b7766f8e6a95935b5431bd49fdbe70 217 Gene3D G3DSA:3.40.50.300 8 209 3.9E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07895 fb45c2ff0a0f70192302f44ee0e8c997 240 Pfam PF00583 Acetyltransferase (GNAT) family 84 141 3.6E-5 T 09-03-2017 IPR000182 GNAT domain GO:0008080 L21SP3_RS07895 fb45c2ff0a0f70192302f44ee0e8c997 240 Gene3D G3DSA:3.40.630.30 87 145 6.2E-6 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS07895 fb45c2ff0a0f70192302f44ee0e8c997 240 SUPERFAMILY SSF55729 85 146 1.52E-7 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS06510 1b5a54bd1aa36d497e816c5b9fdb6ae6 473 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 195 206 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS06510 1b5a54bd1aa36d497e816c5b9fdb6ae6 473 Pfam PF00037 4Fe-4S binding domain 143 164 1.8E-8 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS06510 1b5a54bd1aa36d497e816c5b9fdb6ae6 473 Pfam PF00037 4Fe-4S binding domain 189 210 3.3E-9 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS06510 1b5a54bd1aa36d497e816c5b9fdb6ae6 473 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 228 455 1.1E-46 T 09-03-2017 IPR004108 Iron hydrogenase, large subunit, C-terminal L21SP3_RS06510 1b5a54bd1aa36d497e816c5b9fdb6ae6 473 Gene3D G3DSA:3.30.70.20 114 166 5.7E-14 T 09-03-2017 L21SP3_RS06510 1b5a54bd1aa36d497e816c5b9fdb6ae6 473 TIGRFAM TIGR04105 FeFe_hydrog_B1: [FeFe] hydrogenase, group B1/B3 4 460 7.0E-160 T 09-03-2017 IPR027631 [FeFe] hydrogenase, group B1/B3 L21SP3_RS06510 1b5a54bd1aa36d497e816c5b9fdb6ae6 473 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS06510 1b5a54bd1aa36d497e816c5b9fdb6ae6 473 Gene3D G3DSA:3.30.70.20 170 212 1.7E-13 T 09-03-2017 L21SP3_RS06510 1b5a54bd1aa36d497e816c5b9fdb6ae6 473 Gene3D G3DSA:3.40.950.10 267 352 2.8E-24 T 09-03-2017 L21SP3_RS06510 1b5a54bd1aa36d497e816c5b9fdb6ae6 473 Gene3D G3DSA:3.40.950.10 410 449 2.8E-24 T 09-03-2017 L21SP3_RS06510 1b5a54bd1aa36d497e816c5b9fdb6ae6 473 SUPERFAMILY SSF53920 194 464 2.09E-57 T 09-03-2017 IPR009016 Iron hydrogenase L21SP3_RS06510 1b5a54bd1aa36d497e816c5b9fdb6ae6 473 SUPERFAMILY SSF54862 112 168 1.52E-15 T 09-03-2017 L21SP3_RS06510 1b5a54bd1aa36d497e816c5b9fdb6ae6 473 SUPERFAMILY SSF54862 170 218 3.21E-15 T 09-03-2017 L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 Gene3D G3DSA:3.30.70.870 316 410 2.0E-30 T 09-03-2017 L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 Gene3D G3DSA:2.40.30.10 217 315 1.8E-25 T 09-03-2017 L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 Pfam PF00679 Elongation factor G C-terminus 409 495 6.8E-19 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 SUPERFAMILY SSF54980 410 526 2.97E-24 T 09-03-2017 IPR009022 Elongation factor G, III-V domain L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 PRINTS PR00315 GTP-binding elongation factor signature 135 144 6.6E-15 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 PRINTS PR00315 GTP-binding elongation factor signature 58 66 6.6E-15 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 PRINTS PR00315 GTP-binding elongation factor signature 99 110 6.6E-15 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 PRINTS PR00315 GTP-binding elongation factor signature 8 21 6.6E-15 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 PRINTS PR00315 GTP-binding elongation factor signature 83 93 6.6E-15 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 Gene3D G3DSA:3.40.50.300 4 216 4.6E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 Pfam PF03144 Elongation factor Tu domain 2 231 300 7.1E-8 T 09-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 Gene3D G3DSA:2.40.50.250 496 590 5.0E-35 T 09-03-2017 L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 Gene3D G3DSA:3.30.70.240 411 495 1.7E-23 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 153 4.0E-20 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 SUPERFAMILY SSF52540 2 219 8.56E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 SUPERFAMILY SSF50447 164 311 7.29E-30 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 SMART SM00838 410 497 0.006 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 Pfam PF00009 Elongation factor Tu GTP binding domain 5 207 2.2E-55 T 09-03-2017 L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 SUPERFAMILY SSF54980 314 399 2.09E-13 T 09-03-2017 IPR009022 Elongation factor G, III-V domain L21SP3_RS10575 54be957a48996f3ccf1958dedaaa7276 621 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 6 612 8.7E-256 T 09-03-2017 IPR006298 GTP-binding protein TypA GO:0005525 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 Pfam PF00117 Glutamine amidotransferase class-I 10 190 4.2E-40 T 09-03-2017 IPR017926 Glutamine amidotransferase L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 203 515 1.6E-143 T 09-03-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 4.7E-8 T 09-03-2017 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 PRINTS PR00096 Glutamine amidotransferase superfamily signature 52 61 4.7E-8 T 09-03-2017 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 PRINTS PR00096 Glutamine amidotransferase superfamily signature 167 180 4.7E-8 T 09-03-2017 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 PRINTS PR00097 Anthranilate synthase component II signature 79 90 5.1E-6 T 09-03-2017 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 PRINTS PR00097 Anthranilate synthase component II signature 52 61 5.1E-6 T 09-03-2017 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 PRINTS PR00097 Anthranilate synthase component II signature 167 180 5.1E-6 T 09-03-2017 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 SUPERFAMILY SSF54810 395 515 5.1E-49 T 09-03-2017 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 8 195 1.9E-73 T 09-03-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 Pfam PF02540 NAD synthase 210 279 2.4E-6 T 09-03-2017 IPR022310 NAD/GMP synthase L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 Gene3D G3DSA:3.30.300.10 391 515 2.2E-51 T 09-03-2017 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 Gene3D G3DSA:3.40.50.880 2 214 1.1E-59 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 5 515 52.403 T 09-03-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 SUPERFAMILY SSF52402 183 436 1.92E-55 T 09-03-2017 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 Pfam PF00958 GMP synthase C terminal domain 423 514 1.8E-41 T 09-03-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 SUPERFAMILY SSF52317 6 198 1.87E-56 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS06990 9b436611d48585cd3405415d5a1070df 515 Gene3D G3DSA:3.40.50.620 215 390 2.4E-56 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS07510 881503ff2de4110b38c7431da3469cc3 504 Pfam PF07881 L-fucose isomerase, first N-terminal domain 60 139 4.7E-7 T 09-03-2017 IPR012888 L-fucose isomerase, N-terminal-1 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 L21SP3_RS07510 881503ff2de4110b38c7431da3469cc3 504 SUPERFAMILY SSF53743 15 136 2.35E-33 T 09-03-2017 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 L21SP3_RS07510 881503ff2de4110b38c7431da3469cc3 504 SUPERFAMILY SSF53743 167 340 2.35E-33 T 09-03-2017 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 L21SP3_RS07510 881503ff2de4110b38c7431da3469cc3 504 Gene3D G3DSA:3.40.50.1070 62 138 4.2E-5 T 09-03-2017 IPR012888 L-fucose isomerase, N-terminal-1 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 L21SP3_RS07510 881503ff2de4110b38c7431da3469cc3 504 Gene3D G3DSA:3.20.14.10 329 494 6.3E-10 T 09-03-2017 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 L21SP3_RS07510 881503ff2de4110b38c7431da3469cc3 504 Gene3D G3DSA:3.40.275.10 185 325 9.4E-8 T 09-03-2017 IPR012889 L-fucose isomerase, N-terminal-2 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 L21SP3_RS07510 881503ff2de4110b38c7431da3469cc3 504 Pfam PF07882 L-fucose isomerase, second N-terminal domain 283 339 3.9E-5 T 09-03-2017 IPR012889 L-fucose isomerase, N-terminal-2 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 L21SP3_RS07510 881503ff2de4110b38c7431da3469cc3 504 Pfam PF02952 L-fucose isomerase, C-terminal domain 362 492 8.4E-9 T 09-03-2017 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 L21SP3_RS04690 65df9c0723dddaf990c9714121eff287 560 SUPERFAMILY SSF52540 168 558 5.89E-98 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04690 65df9c0723dddaf990c9714121eff287 560 Pfam PF00437 Type II/IV secretion system protein 185 452 2.7E-80 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS04690 65df9c0723dddaf990c9714121eff287 560 Gene3D G3DSA:3.40.50.300 290 558 2.6E-100 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04690 65df9c0723dddaf990c9714121eff287 560 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 380 394 - T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS04690 65df9c0723dddaf990c9714121eff287 560 Gene3D G3DSA:3.30.450.90 157 285 1.4E-47 T 09-03-2017 L21SP3_RS04690 65df9c0723dddaf990c9714121eff287 560 SUPERFAMILY SSF160246 4 136 7.32E-16 T 09-03-2017 L21SP3_RS04690 65df9c0723dddaf990c9714121eff287 560 SMART SM00382 313 436 6.6E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS04690 65df9c0723dddaf990c9714121eff287 560 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 42 137 4.5E-14 T 09-03-2017 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 L21SP3_RS01890 9b19f6ee990d3deaa2bd1fae18bdaa18 213 Gene3D G3DSA:3.40.50.10300 1 205 5.2E-67 T 09-03-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 L21SP3_RS01890 9b19f6ee990d3deaa2bd1fae18bdaa18 213 SUPERFAMILY SSF102645 2 206 3.4E-62 T 09-03-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 L21SP3_RS01890 9b19f6ee990d3deaa2bd1fae18bdaa18 213 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 2 165 3.5E-62 T 09-03-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 L21SP3_RS10175 3621cc4e0d8e2e7739431e261a17d3f7 132 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 115 2.1E-19 T 09-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 L21SP3_RS10175 3621cc4e0d8e2e7739431e261a17d3f7 132 Gene3D G3DSA:3.30.300.20 3 116 3.2E-25 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta L21SP3_RS10175 3621cc4e0d8e2e7739431e261a17d3f7 132 Pfam PF02033 Ribosome-binding factor A 6 108 2.1E-20 T 09-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 L21SP3_RS10175 3621cc4e0d8e2e7739431e261a17d3f7 132 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 15 97 5.0E-14 T 09-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 L21SP3_RS10175 3621cc4e0d8e2e7739431e261a17d3f7 132 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 121 17.218 T 09-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 L21SP3_RS10175 3621cc4e0d8e2e7739431e261a17d3f7 132 SUPERFAMILY SSF89919 1 101 3.79E-22 T 09-03-2017 IPR023799 Ribosome-binding factor A domain L21SP3_RS10775 35e5221176a8250a80802a3f06700063 229 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 227 37.884 T 09-03-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 L21SP3_RS10775 35e5221176a8250a80802a3f06700063 229 Gene3D G3DSA:3.40.50.790 67 157 7.9E-35 T 09-03-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich L21SP3_RS10775 35e5221176a8250a80802a3f06700063 229 Pfam PF00687 Ribosomal protein L1p/L10e family 28 218 6.1E-49 T 09-03-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein L21SP3_RS10775 35e5221176a8250a80802a3f06700063 229 Gene3D G3DSA:3.30.190.20 17 66 5.2E-41 T 09-03-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 L21SP3_RS10775 35e5221176a8250a80802a3f06700063 229 Gene3D G3DSA:3.30.190.20 159 224 5.2E-41 T 09-03-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 L21SP3_RS10775 35e5221176a8250a80802a3f06700063 229 PIRSF PIRSF002155 1 225 3.2E-75 T 09-03-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS10775 35e5221176a8250a80802a3f06700063 229 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 225 1.2E-88 T 09-03-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 L21SP3_RS10775 35e5221176a8250a80802a3f06700063 229 SUPERFAMILY SSF56808 15 223 2.49E-72 T 09-03-2017 IPR023674 Ribosomal protein L1-like L21SP3_RS05845 478d80a9962d303d049718374929b5ab 335 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 117 2.3E-34 T 09-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 L21SP3_RS05845 478d80a9962d303d049718374929b5ab 335 SUPERFAMILY SSF51735 4 154 7.1E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS05845 478d80a9962d303d049718374929b5ab 335 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 334 34.82 T 09-03-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 L21SP3_RS05845 478d80a9962d303d049718374929b5ab 335 PIRSF PIRSF000148 2 334 2.2E-125 T 09-03-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 L21SP3_RS05845 478d80a9962d303d049718374929b5ab 335 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 139 320 4.2E-47 T 09-03-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 L21SP3_RS05845 478d80a9962d303d049718374929b5ab 335 Gene3D G3DSA:3.30.360.10 141 316 8.0E-75 T 09-03-2017 L21SP3_RS05845 478d80a9962d303d049718374929b5ab 335 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 333 1.6E-125 T 09-03-2017 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 L21SP3_RS05845 478d80a9962d303d049718374929b5ab 335 SMART SM00859 4 119 4.5E-44 T 09-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 L21SP3_RS05845 478d80a9962d303d049718374929b5ab 335 SUPERFAMILY SSF55347 127 321 5.66E-65 T 09-03-2017 L21SP3_RS05845 478d80a9962d303d049718374929b5ab 335 Gene3D G3DSA:3.40.50.720 2 140 4.8E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS11500 7f5f199605598e52e86cad8a1f689baf 202 PRINTS PR00394 RHS protein signature 30 49 1.7E-6 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11500 7f5f199605598e52e86cad8a1f689baf 202 PRINTS PR00394 RHS protein signature 7 27 1.7E-6 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11500 7f5f199605598e52e86cad8a1f689baf 202 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 10 62 3.3E-21 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 L21SP3_RS07220 140cd838c4c6f670ef0c8e02b9ca6db5 1051 SMART SM00487 228 407 1.1E-11 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain L21SP3_RS07220 140cd838c4c6f670ef0c8e02b9ca6db5 1051 SUPERFAMILY SSF52540 220 404 1.08E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07220 140cd838c4c6f670ef0c8e02b9ca6db5 1051 SUPERFAMILY SSF56024 116 182 4.71E-6 T 09-03-2017 L21SP3_RS07220 140cd838c4c6f670ef0c8e02b9ca6db5 1051 SMART SM00490 699 800 2.4E-14 T 09-03-2017 IPR001650 Helicase, C-terminal L21SP3_RS07220 140cd838c4c6f670ef0c8e02b9ca6db5 1051 Gene3D G3DSA:3.40.50.300 661 846 1.7E-25 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07220 140cd838c4c6f670ef0c8e02b9ca6db5 1051 Pfam PF00176 SNF2 family N-terminal domain 247 394 6.6E-10 T 09-03-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 L21SP3_RS07220 140cd838c4c6f670ef0c8e02b9ca6db5 1051 SUPERFAMILY SSF52540 339 393 9.58E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07220 140cd838c4c6f670ef0c8e02b9ca6db5 1051 SUPERFAMILY SSF52540 655 827 9.58E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07220 140cd838c4c6f670ef0c8e02b9ca6db5 1051 Pfam PF13091 PLD-like domain 29 176 2.0E-11 T 09-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 L21SP3_RS07220 140cd838c4c6f670ef0c8e02b9ca6db5 1051 Gene3D G3DSA:3.40.50.300 226 393 1.6E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07220 140cd838c4c6f670ef0c8e02b9ca6db5 1051 Gene3D G3DSA:3.30.870.10 104 184 2.3E-7 T 09-03-2017 L21SP3_RS07220 140cd838c4c6f670ef0c8e02b9ca6db5 1051 Pfam PF00271 Helicase conserved C-terminal domain 665 798 2.3E-17 T 09-03-2017 IPR001650 Helicase, C-terminal L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 442 456 - T 09-03-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 SMART SM01038 749 1018 6.2E-79 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 SUPERFAMILY SSF74650 739 1020 2.67E-63 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 Gene3D G3DSA:2.60.120.260 5 203 8.6E-84 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 328 623 8.0E-95 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 378 403 - T 09-03-2017 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 Pfam PF02929 Beta galactosidase small chain 752 1017 2.9E-59 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 SUPERFAMILY SSF51445 328 618 3.8E-80 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 Pfam PF16353 Domain of unknown function(DUF4981) 634 722 1.2E-19 T 09-03-2017 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 SUPERFAMILY SSF49303 216 326 3.74E-25 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 Gene3D G3DSA:3.20.20.80 327 617 7.4E-92 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 SUPERFAMILY SSF49303 616 725 1.29E-23 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 46 213 1.2E-48 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 Gene3D G3DSA:2.60.40.320 204 326 7.4E-36 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 SUPERFAMILY SSF49785 8 214 2.98E-67 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 337 351 3.5E-32 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 442 457 3.5E-32 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 368 386 3.5E-32 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 142 157 3.5E-32 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 516 531 3.5E-32 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 Gene3D G3DSA:2.70.98.10 738 1020 2.0E-72 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 Gene3D G3DSA:2.60.40.320 620 723 2.4E-27 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS00035 d9228d611f9c62d2f0c275609aefe706 1034 Pfam PF00703 Glycosyl hydrolases family 2 216 326 9.0E-22 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS04395 89162d75b2dd557188efd2fc6b7dc73f 768 SUPERFAMILY SSF53474 511 755 8.61E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS04395 89162d75b2dd557188efd2fc6b7dc73f 768 Gene3D G3DSA:2.140.10.30 41 500 3.7E-56 T 09-03-2017 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 L21SP3_RS04395 89162d75b2dd557188efd2fc6b7dc73f 768 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 138 478 2.9E-36 T 09-03-2017 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 L21SP3_RS04395 89162d75b2dd557188efd2fc6b7dc73f 768 Gene3D G3DSA:3.40.50.1820 508 756 1.9E-61 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS04395 89162d75b2dd557188efd2fc6b7dc73f 768 Pfam PF00326 Prolyl oligopeptidase family 566 755 5.9E-43 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 L21SP3_RS04395 89162d75b2dd557188efd2fc6b7dc73f 768 SUPERFAMILY SSF82171 106 491 4.32E-26 T 09-03-2017 L21SP3_RS06600 534e44839abfc1d48aa7ea9d099e3c81 449 Gene3D G3DSA:3.30.1120.10 392 441 3.7E-17 T 09-03-2017 L21SP3_RS06600 534e44839abfc1d48aa7ea9d099e3c81 449 Gene3D G3DSA:3.30.1120.10 339 354 3.7E-17 T 09-03-2017 L21SP3_RS06600 534e44839abfc1d48aa7ea9d099e3c81 449 SUPERFAMILY SSF53649 390 435 4.36E-99 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS06600 534e44839abfc1d48aa7ea9d099e3c81 449 SUPERFAMILY SSF53649 23 352 4.36E-99 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS06600 534e44839abfc1d48aa7ea9d099e3c81 449 Pfam PF00884 Sulfatase 25 129 1.6E-22 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS06600 534e44839abfc1d48aa7ea9d099e3c81 449 Pfam PF00884 Sulfatase 153 290 6.9E-18 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS06600 534e44839abfc1d48aa7ea9d099e3c81 449 Gene3D G3DSA:3.40.720.10 152 338 2.2E-41 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS06600 534e44839abfc1d48aa7ea9d099e3c81 449 Pfam PF16347 Domain of unknown function (DUF4976) 383 433 1.0E-7 T 09-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 L21SP3_RS06600 534e44839abfc1d48aa7ea9d099e3c81 449 Gene3D G3DSA:3.40.720.10 23 129 2.2E-36 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS02635 b76444753d8fc68f49a51b0885ee1f77 398 SUPERFAMILY SSF52540 8 234 1.17E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02635 b76444753d8fc68f49a51b0885ee1f77 398 Pfam PF00005 ABC transporter 30 171 5.9E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS02635 b76444753d8fc68f49a51b0885ee1f77 398 SMART SM00382 38 218 5.0E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS02635 b76444753d8fc68f49a51b0885ee1f77 398 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS02635 b76444753d8fc68f49a51b0885ee1f77 398 Gene3D G3DSA:3.40.50.300 4 238 3.1E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08745 e0287d876046de887fe9988336213334 539 Pfam PF00884 Sulfatase 36 427 1.6E-87 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS08745 e0287d876046de887fe9988336213334 539 Gene3D G3DSA:3.40.720.10 33 451 2.7E-135 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08745 e0287d876046de887fe9988336213334 539 ProSitePatterns PS00149 Sulfatases signature 2. 138 148 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS08745 e0287d876046de887fe9988336213334 539 SUPERFAMILY SSF53649 35 528 3.34E-155 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS08745 e0287d876046de887fe9988336213334 539 Gene3D G3DSA:3.30.1120.10 456 534 1.2E-23 T 09-03-2017 L21SP3_RS08745 e0287d876046de887fe9988336213334 539 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 6 30 1.7E-5 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal L21SP3_RS00510 329cf3c0cdfc536f4f0f8242af9757c2 314 TIGRFAM TIGR02602 8TM_EpsH: exosortase 39 285 2.1E-43 T 09-03-2017 IPR013426 Exosortase, EpsH L21SP3_RS00510 329cf3c0cdfc536f4f0f8242af9757c2 314 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 194 288 8.1E-24 T 09-03-2017 IPR026392 Exosortase/Archaeosortase domain L21SP3_RS00510 329cf3c0cdfc536f4f0f8242af9757c2 314 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 25 285 8.4E-54 T 09-03-2017 IPR019127 Exosortase EpsH-related L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 SUPERFAMILY SSF49303 186 296 2.79E-17 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 Pfam PF16355 Domain of unknown function (DUF4982) 650 710 1.3E-25 T 09-03-2017 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 Gene3D G3DSA:2.60.40.920 723 824 4.3E-5 T 09-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 Gene3D G3DSA:2.60.40.320 174 298 1.4E-27 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 PRINTS PR00132 Glycosyl hydrolase family 2 signature 309 323 3.0E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 PRINTS PR00132 Glycosyl hydrolase family 2 signature 115 130 3.0E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 PRINTS PR00132 Glycosyl hydrolase family 2 signature 410 425 3.0E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 PRINTS PR00132 Glycosyl hydrolase family 2 signature 340 358 3.0E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 44 182 6.0E-19 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 Gene3D G3DSA:3.20.20.80 301 633 5.5E-84 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 304 501 1.5E-30 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 Pfam PF00703 Glycosyl hydrolases family 2 187 297 3.0E-19 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 SUPERFAMILY SSF51445 294 571 4.22E-81 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 SUPERFAMILY SSF51445 610 631 4.22E-81 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 Gene3D G3DSA:2.60.120.260 19 173 4.1E-44 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 Gene3D G3DSA:2.60.40.1560 637 722 4.0E-34 T 09-03-2017 L21SP3_RS01460 f5ecef6e5ea052891e778584faaf03fc 829 SUPERFAMILY SSF49785 11 183 5.1E-43 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS02220 ece8840ccb14455f521567890e46bb97 361 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 6 360 6.1E-140 T 09-03-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 L21SP3_RS02220 ece8840ccb14455f521567890e46bb97 361 Gene3D G3DSA:3.30.160.20 216 293 2.5E-28 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain L21SP3_RS02220 ece8840ccb14455f521567890e46bb97 361 SUPERFAMILY SSF75620 15 358 6.15E-115 T 09-03-2017 L21SP3_RS02220 ece8840ccb14455f521567890e46bb97 361 Pfam PF03462 PCRF domain 15 209 1.9E-61 T 09-03-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 L21SP3_RS02220 ece8840ccb14455f521567890e46bb97 361 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 233 249 - T 09-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 L21SP3_RS02220 ece8840ccb14455f521567890e46bb97 361 SMART SM00937 70 184 5.9E-43 T 09-03-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 L21SP3_RS02220 ece8840ccb14455f521567890e46bb97 361 Gene3D G3DSA:1.20.58.410 11 97 2.3E-16 T 09-03-2017 L21SP3_RS02220 ece8840ccb14455f521567890e46bb97 361 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 8 361 34.728 T 09-03-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 L21SP3_RS02220 ece8840ccb14455f521567890e46bb97 361 Pfam PF00472 RF-1 domain 217 326 3.6E-36 T 09-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 L21SP3_RS09890 dbef7ae981be50693c27c717e254293d 452 SUPERFAMILY SSF46600 190 239 1.96E-10 T 09-03-2017 IPR001943 UVR domain GO:0005515 L21SP3_RS09890 dbef7ae981be50693c27c717e254293d 452 Gene3D G3DSA:4.10.860.10 182 239 5.6E-15 T 09-03-2017 IPR001943 UVR domain GO:0005515 L21SP3_RS09890 dbef7ae981be50693c27c717e254293d 452 SUPERFAMILY SSF82771 7 95 4.18E-15 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily L21SP3_RS09890 dbef7ae981be50693c27c717e254293d 452 SMART SM00465 7 93 2.9E-15 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily L21SP3_RS09890 dbef7ae981be50693c27c717e254293d 452 Gene3D G3DSA:3.40.1440.10 8 88 2.4E-4 T 09-03-2017 IPR027299 GIY-YIG domain L21SP3_RS09890 dbef7ae981be50693c27c717e254293d 452 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 267 415 5.3E-42 T 09-03-2017 IPR001162 UvrC family homology region L21SP3_RS09890 dbef7ae981be50693c27c717e254293d 452 Pfam PF02151 UvrB/uvrC motif 206 238 5.4E-11 T 09-03-2017 IPR001943 UVR domain GO:0005515 L21SP3_RS09890 dbef7ae981be50693c27c717e254293d 452 Pfam PF01541 GIY-YIG catalytic domain 9 88 3.7E-5 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily L21SP3_RS03460 422321efa0c5e54cbcef4c198e74b320 284 Pfam PF12146 Serine aminopeptidase, S33 39 266 8.5E-34 T 09-03-2017 IPR022742 Serine aminopeptidase, S33 L21SP3_RS03460 422321efa0c5e54cbcef4c198e74b320 284 SUPERFAMILY SSF53474 20 279 3.24E-32 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS03460 422321efa0c5e54cbcef4c198e74b320 284 Gene3D G3DSA:3.40.50.1820 28 279 7.8E-33 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 34 193 4.2E-25 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 Pfam PF00703 Glycosyl hydrolases family 2 204 306 1.3E-14 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 SUPERFAMILY SSF49303 199 304 1.53E-13 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 313 512 2.1E-30 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 SUPERFAMILY SSF49785 26 195 2.41E-41 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 431 445 - T 09-03-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 Gene3D G3DSA:2.60.40.320 186 306 1.3E-23 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 Gene3D G3DSA:3.20.20.80 313 595 8.2E-72 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 Gene3D G3DSA:2.60.120.260 35 185 1.4E-41 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 SUPERFAMILY SSF51445 313 597 5.63E-64 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 PRINTS PR00132 Glycosyl hydrolase family 2 signature 349 367 3.7E-13 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 PRINTS PR00132 Glycosyl hydrolase family 2 signature 431 446 3.7E-13 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 PRINTS PR00132 Glycosyl hydrolase family 2 signature 123 138 3.7E-13 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS01885 79aab162e2558b5eb65d375f8a8e2a14 787 PRINTS PR00132 Glycosyl hydrolase family 2 signature 318 332 3.7E-13 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS02115 54c404914f9d2ab6c439b1c63609c27b 713 Pfam PF07679 Immunoglobulin I-set domain 360 453 1.5E-8 T 09-03-2017 IPR013098 Immunoglobulin I-set L21SP3_RS02115 54c404914f9d2ab6c439b1c63609c27b 713 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 522 659 1.3E-19 T 09-03-2017 L21SP3_RS02115 54c404914f9d2ab6c439b1c63609c27b 713 SUPERFAMILY SSF48726 356 455 2.72E-13 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS02115 54c404914f9d2ab6c439b1c63609c27b 713 Gene3D G3DSA:2.60.120.200 456 665 6.2E-27 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS02115 54c404914f9d2ab6c439b1c63609c27b 713 Gene3D G3DSA:2.60.40.10 356 455 2.9E-14 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS02115 54c404914f9d2ab6c439b1c63609c27b 713 SMART SM00409 362 455 2.7E-7 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS02115 54c404914f9d2ab6c439b1c63609c27b 713 SUPERFAMILY SSF49899 449 664 3.17E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS11550 8fc10e958b59e51453d36c6e6fc20c5e 490 ProDom PD113327 YESU 3D-STRUCTURE 276 489 5.0E-29 T 09-03-2017 IPR015305 Protein of unknown function DUF1961 L21SP3_RS11550 8fc10e958b59e51453d36c6e6fc20c5e 490 SUPERFAMILY SSF49899 272 487 1.36E-39 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS11550 8fc10e958b59e51453d36c6e6fc20c5e 490 Pfam PF09224 Domain of unknown function (DUF1961) 274 484 7.0E-40 T 09-03-2017 IPR015305 Protein of unknown function DUF1961 L21SP3_RS11550 8fc10e958b59e51453d36c6e6fc20c5e 490 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 95 228 6.8E-7 T 09-03-2017 L21SP3_RS11550 8fc10e958b59e51453d36c6e6fc20c5e 490 Gene3D G3DSA:2.60.120.200 67 237 2.0E-6 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS11550 8fc10e958b59e51453d36c6e6fc20c5e 490 SUPERFAMILY SSF49899 85 238 1.22E-8 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS11550 8fc10e958b59e51453d36c6e6fc20c5e 490 Gene3D G3DSA:2.60.120.200 272 488 8.4E-47 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS09105 674ffe65a55f5aa08d7d3dff0fe46570 284 Pfam PF06230 Protein of unknown function (DUF1009) 65 281 1.4E-64 T 09-03-2017 IPR010415 Protein of unknown function DUF1009 L21SP3_RS06245 7e9b4e9b7934379c4c741db2456b155e 124 TIGRFAM TIGR04535 ferrit_encaps: ferritin-like protein 6 121 3.3E-38 T 09-03-2017 IPR030907 Ferritin-like protein L21SP3_RS06245 7e9b4e9b7934379c4c741db2456b155e 124 SUPERFAMILY SSF47240 5 88 1.18E-17 T 09-03-2017 IPR009078 Ferritin-like superfamily L21SP3_RS06245 7e9b4e9b7934379c4c741db2456b155e 124 Gene3D G3DSA:1.20.1260.10 27 73 9.1E-12 T 09-03-2017 IPR012347 Ferritin-related L21SP3_RS06245 7e9b4e9b7934379c4c741db2456b155e 124 TIGRFAM TIGR04537 encap_target: encapsulation C-terminal sorting signal 113 122 0.071 T 09-03-2017 L21SP3_RS01275 fe0a7c0cc18cbc1dbe185c6e768fe37a 427 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 33 210 3.9E-55 T 09-03-2017 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 L21SP3_RS01275 fe0a7c0cc18cbc1dbe185c6e768fe37a 427 SUPERFAMILY SSF53756 55 412 5.76E-16 T 09-03-2017 L21SP3_RS01275 fe0a7c0cc18cbc1dbe185c6e768fe37a 427 Gene3D G3DSA:3.40.50.2000 201 406 9.6E-6 T 09-03-2017 L21SP3_RS02125 4f6db0f68f0917fc5d4b1cb427a86427 149 Pfam PF01609 Transposase DDE domain 6 69 9.8E-7 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS02125 4f6db0f68f0917fc5d4b1cb427a86427 149 SUPERFAMILY SSF53098 7 142 4.32E-8 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS05225 56cd8afc33c9f6182728fe70d8eff860 229 SUPERFAMILY SSF52266 40 229 7.0E-28 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS05225 56cd8afc33c9f6182728fe70d8eff860 229 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 46 220 2.6E-15 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS05225 56cd8afc33c9f6182728fe70d8eff860 229 Gene3D G3DSA:3.40.50.1110 41 227 1.1E-25 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS04550 23daeb797769b2d39892fcd56df66020 892 SUPERFAMILY SSF117281 57 356 5.23E-26 T 09-03-2017 L21SP3_RS04550 23daeb797769b2d39892fcd56df66020 892 Pfam PF13964 Kelch motif 157 213 9.6E-6 T 09-03-2017 L21SP3_RS04550 23daeb797769b2d39892fcd56df66020 892 Gene3D G3DSA:2.120.10.80 77 360 7.0E-26 T 09-03-2017 IPR015915 Kelch-type beta propeller GO:0005515 L21SP3_RS04550 23daeb797769b2d39892fcd56df66020 892 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 425 831 1.7E-64 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS04550 23daeb797769b2d39892fcd56df66020 892 Pfam PF00474 Sodium:solute symporter family 425 831 2.8E-40 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 267 280 - T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 Gene3D G3DSA:3.40.50.300 97 295 3.6E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 440 33.307 T 09-03-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 Pfam PF02978 Signal peptide binding domain 325 422 3.5E-30 T 09-03-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 SUPERFAMILY SSF47446 325 425 1.47E-32 T 09-03-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 5.8E-23 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 SMART SM00962 100 294 1.6E-110 T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 SMART SM00382 99 245 9.5E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 Pfam PF00448 SRP54-type protein, GTPase domain 100 294 2.0E-77 T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 Gene3D G3DSA:1.20.120.140 2 89 1.9E-34 T 09-03-2017 L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 SUPERFAMILY SSF52540 42 352 2.44E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 424 5.6E-180 T 09-03-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 Gene3D G3DSA:1.10.260.30 325 426 1.5E-34 T 09-03-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 L21SP3_RS01810 0e0566fabb3a9f05b794840b320a9a58 475 SMART SM00963 1 86 3.7E-35 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 L21SP3_RS05685 deb47563eb4f6ab91a0923560189b27a 115 Gene3D G3DSA:3.30.780.10 36 115 1.1E-32 T 09-03-2017 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 L21SP3_RS05685 deb47563eb4f6ab91a0923560189b27a 115 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 8 115 5.9E-36 T 09-03-2017 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 L21SP3_RS05685 deb47563eb4f6ab91a0923560189b27a 115 Pfam PF01253 Translation initiation factor SUI1 38 109 3.5E-18 T 09-03-2017 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 L21SP3_RS05685 deb47563eb4f6ab91a0923560189b27a 115 PIRSF PIRSF037511 1 115 5.3E-34 T 09-03-2017 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 L21SP3_RS05685 deb47563eb4f6ab91a0923560189b27a 115 SUPERFAMILY SSF55159 4 111 1.83E-30 T 09-03-2017 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 L21SP3_RS10770 9a944a857389063ea91ccaf09a95b8d5 140 Gene3D G3DSA:1.10.10.250 72 139 7.8E-30 T 09-03-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP3_RS10770 9a944a857389063ea91ccaf09a95b8d5 140 SUPERFAMILY SSF54747 1 84 8.24E-29 T 09-03-2017 IPR020784 Ribosomal protein L11, N-terminal L21SP3_RS10770 9a944a857389063ea91ccaf09a95b8d5 140 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 38 73 4.0E-10 T 09-03-2017 L21SP3_RS10770 9a944a857389063ea91ccaf09a95b8d5 140 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 1.4E-23 T 09-03-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP3_RS10770 9a944a857389063ea91ccaf09a95b8d5 140 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 4.1E-27 T 09-03-2017 IPR020784 Ribosomal protein L11, N-terminal L21SP3_RS10770 9a944a857389063ea91ccaf09a95b8d5 140 SMART SM00649 9 140 7.9E-76 T 09-03-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS10770 9a944a857389063ea91ccaf09a95b8d5 140 SUPERFAMILY SSF46906 67 139 1.7E-25 T 09-03-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP3_RS10770 9a944a857389063ea91ccaf09a95b8d5 140 Gene3D G3DSA:3.30.1550.10 2 71 6.5E-33 T 09-03-2017 IPR020784 Ribosomal protein L11, N-terminal L21SP3_RS10770 9a944a857389063ea91ccaf09a95b8d5 140 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 140 29.466 T 09-03-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS10770 9a944a857389063ea91ccaf09a95b8d5 140 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 139 5.5E-57 T 09-03-2017 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS09950 e8e4ea25e1cde51dff843ef534d97fba 141 Pfam PF03652 Holliday junction resolvase 3 134 1.5E-37 T 09-03-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 L21SP3_RS09950 e8e4ea25e1cde51dff843ef534d97fba 141 SUPERFAMILY SSF53098 3 135 1.82E-34 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS09950 e8e4ea25e1cde51dff843ef534d97fba 141 Gene3D G3DSA:3.30.420.140 3 137 2.2E-42 T 09-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 L21SP3_RS09950 e8e4ea25e1cde51dff843ef534d97fba 141 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 3 137 20.985 T 09-03-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 L21SP3_RS09950 e8e4ea25e1cde51dff843ef534d97fba 141 SMART SM00732 3 102 2.5E-26 T 09-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 L21SP3_RS09950 e8e4ea25e1cde51dff843ef534d97fba 141 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 6 134 1.2E-26 T 09-03-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 Pfam PF00975 Thioesterase domain 620 722 1.8E-17 T 09-03-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 Pfam PF00550 Phosphopantetheine attachment site 534 593 1.3E-6 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 Pfam PF00501 AMP-binding enzyme 27 415 2.2E-77 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 Gene3D G3DSA:3.40.50.980 21 172 2.2E-35 T 09-03-2017 L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 Pfam PF13193 AMP-binding enzyme C-terminal domain 424 497 2.5E-8 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 SUPERFAMILY SSF47336 522 593 3.27E-15 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 SUPERFAMILY SSF56801 19 540 6.93E-120 T 09-03-2017 L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 49 440 5.2E-106 T 09-03-2017 IPR010071 Amino acid adenylation domain L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 SUPERFAMILY SSF53474 599 723 1.44E-32 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 Gene3D G3DSA:3.40.50.980 173 320 6.2E-29 T 09-03-2017 L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 Gene3D G3DSA:1.10.1200.10 534 594 3.2E-18 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 Gene3D G3DSA:3.40.50.1820 602 721 3.7E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 Gene3D G3DSA:3.30.300.30 412 533 5.2E-30 T 09-03-2017 L21SP3_RS11240 aaa1fc6c8caf8a606dfc526e6b9ea507 728 Gene3D G3DSA:2.30.38.10 328 406 4.4E-25 T 09-03-2017 L21SP3_RS01585 290e54640ff6484035c13e1526e13cdd 373 SMART SM00729 4 220 9.4E-44 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP3_RS01585 290e54640ff6484035c13e1526e13cdd 373 Pfam PF06969 HemN C-terminal domain 296 360 1.2E-9 T 09-03-2017 IPR010723 HemN, C-terminal L21SP3_RS01585 290e54640ff6484035c13e1526e13cdd 373 Gene3D G3DSA:3.80.30.20 6 236 1.6E-30 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe L21SP3_RS01585 290e54640ff6484035c13e1526e13cdd 373 SUPERFAMILY SSF102114 6 371 9.02E-91 T 09-03-2017 L21SP3_RS01585 290e54640ff6484035c13e1526e13cdd 373 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 5 341 3.0E-79 T 09-03-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 L21SP3_RS01585 290e54640ff6484035c13e1526e13cdd 373 Pfam PF04055 Radical SAM superfamily 9 174 1.5E-15 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 Gene3D G3DSA:2.160.20.10 605 741 5.8E-27 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 Gene3D G3DSA:2.160.20.10 778 952 5.8E-27 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 Gene3D G3DSA:2.160.20.10 1456 1457 1.7E-4 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 Gene3D G3DSA:2.160.20.10 1490 1569 1.7E-4 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 Gene3D G3DSA:2.160.20.10 1668 1833 6.9E-7 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 Gene3D G3DSA:2.160.20.10 1352 1424 1.7E-4 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 1544 1567 2800.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 1772 1797 4300.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 1410 1440 6400.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 1911 1933 7700.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 861 882 4500.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 990 1040 5400.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 938 964 63.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 781 802 4900.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 2022 2046 3000.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 1490 1538 1900.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 1952 1978 2800.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 835 856 7500.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 884 910 7600.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 720 742 6300.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00710 1808 1833 2900.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SUPERFAMILY SSF51126 603 665 2.09E-27 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SUPERFAMILY SSF51126 795 1099 2.09E-27 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SUPERFAMILY SSF51126 710 734 2.09E-27 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 Gene3D G3DSA:3.40.390.10 350 414 2.5E-5 T 09-03-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 235 504 3.7E-43 T 09-03-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SMART SM00539 2197 2351 2.5E-5 T 09-03-2017 IPR003886 NIDO domain GO:0007160 L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 SUPERFAMILY SSF51126 1908 2067 7.07E-5 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS00905 d5e664e390896ebcd39f1e6a5fad064a 2951 Pfam PF13229 Right handed beta helix region 737 918 8.7E-5 T 09-03-2017 L21SP3_RS02295 dd749b025004d85ade1d22095addbfce 429 SUPERFAMILY SSF56672 16 247 4.18E-65 T 09-03-2017 L21SP3_RS02295 dd749b025004d85ade1d22095addbfce 429 Gene3D G3DSA:3.30.70.270 82 168 7.7E-22 T 09-03-2017 L21SP3_RS02295 dd749b025004d85ade1d22095addbfce 429 Pfam PF13438 Domain of unknown function (DUF4113) 378 426 4.9E-16 T 09-03-2017 IPR025188 Domain of unknown function DUF4113 L21SP3_RS02295 dd749b025004d85ade1d22095addbfce 429 Pfam PF00817 impB/mucB/samB family 19 162 2.5E-36 T 09-03-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 L21SP3_RS02295 dd749b025004d85ade1d22095addbfce 429 Gene3D G3DSA:1.10.150.20 181 248 1.3E-13 T 09-03-2017 L21SP3_RS02295 dd749b025004d85ade1d22095addbfce 429 Pfam PF11799 impB/mucB/samB family C-terminal domain 251 359 1.1E-4 T 09-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 L21SP3_RS06465 530a17651a4c5815afcf268b447b381c 87 SUPERFAMILY SSF52833 3 85 2.35E-13 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS06465 530a17651a4c5815afcf268b447b381c 87 Gene3D G3DSA:3.40.30.10 4 85 6.4E-11 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS06465 530a17651a4c5815afcf268b447b381c 87 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 3 77 2.4E-11 T 09-03-2017 L21SP3_RS02565 6d8263d95eb710a8868b01be2a59ee8a 663 SUPERFAMILY SSF52518 4 325 2.95E-112 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS02565 6d8263d95eb710a8868b01be2a59ee8a 663 Pfam PF02779 Transketolase, pyrimidine binding domain 354 524 1.6E-43 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain L21SP3_RS02565 6d8263d95eb710a8868b01be2a59ee8a 663 Pfam PF02780 Transketolase, C-terminal domain 548 653 6.5E-10 T 09-03-2017 IPR033248 Transketolase, C-terminal domain L21SP3_RS02565 6d8263d95eb710a8868b01be2a59ee8a 663 SUPERFAMILY SSF52518 343 527 2.6E-61 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS02565 6d8263d95eb710a8868b01be2a59ee8a 663 Gene3D G3DSA:3.40.50.970 4 326 1.1E-123 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS02565 6d8263d95eb710a8868b01be2a59ee8a 663 Gene3D G3DSA:3.40.50.970 327 535 7.8E-70 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS02565 6d8263d95eb710a8868b01be2a59ee8a 663 Gene3D G3DSA:3.40.50.920 539 662 7.9E-42 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP3_RS02565 6d8263d95eb710a8868b01be2a59ee8a 663 SMART SM00861 354 526 5.5E-59 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain L21SP3_RS02565 6d8263d95eb710a8868b01be2a59ee8a 663 TIGRFAM TIGR00232 tktlase_bact: transketolase 7 661 3.1E-260 T 09-03-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 L21SP3_RS02565 6d8263d95eb710a8868b01be2a59ee8a 663 ProSitePatterns PS00801 Transketolase signature 1. 13 33 - T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 L21SP3_RS02565 6d8263d95eb710a8868b01be2a59ee8a 663 SUPERFAMILY SSF52922 534 663 3.01E-39 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP3_RS02565 6d8263d95eb710a8868b01be2a59ee8a 663 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 5 338 1.4E-148 T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 L21SP3_RS02565 6d8263d95eb710a8868b01be2a59ee8a 663 ProSitePatterns PS00802 Transketolase signature 2. 467 483 - T 09-03-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 L21SP3_RS09235 75fcc70205708bb5db3888707980ab32 543 Gene3D G3DSA:3.40.720.10 56 421 2.3E-113 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS09235 75fcc70205708bb5db3888707980ab32 543 Gene3D G3DSA:3.40.720.10 478 540 2.3E-113 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS09235 75fcc70205708bb5db3888707980ab32 543 SUPERFAMILY SSF53649 478 538 4.51E-99 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09235 75fcc70205708bb5db3888707980ab32 543 SUPERFAMILY SSF53649 52 421 4.51E-99 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09235 75fcc70205708bb5db3888707980ab32 543 Pfam PF00245 Alkaline phosphatase 60 534 1.8E-66 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS09235 75fcc70205708bb5db3888707980ab32 543 Gene3D G3DSA:1.10.1330.10 25 55 7.8E-4 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS09235 75fcc70205708bb5db3888707980ab32 543 ProSitePatterns PS00018 EF-hand calcium-binding domain. 33 45 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS09235 75fcc70205708bb5db3888707980ab32 543 SMART SM00098 60 537 2.6E-34 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS09235 75fcc70205708bb5db3888707980ab32 543 PRINTS PR00113 Alkaline phosphatase signature 296 325 7.6E-19 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS09235 75fcc70205708bb5db3888707980ab32 543 PRINTS PR00113 Alkaline phosphatase signature 166 186 7.6E-19 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS09235 75fcc70205708bb5db3888707980ab32 543 PRINTS PR00113 Alkaline phosphatase signature 210 220 7.6E-19 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS09235 75fcc70205708bb5db3888707980ab32 543 PRINTS PR00113 Alkaline phosphatase signature 59 79 7.6E-19 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 42.418 T 09-03-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 SUPERFAMILY SSF81271 282 362 1.29E-36 T 09-03-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 SUPERFAMILY SSF52540 3 304 1.23E-77 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 2.1E-33 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 71 86 2.1E-33 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.1E-33 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 2.1E-33 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 2.0E-40 T 09-03-2017 IPR013029 Domain of unknown function DUF933 L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 Pfam PF01926 50S ribosome-binding GTPase 5 122 1.2E-22 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 Gene3D G3DSA:1.10.150.300 132 202 2.2E-23 T 09-03-2017 IPR023192 TGS-like domain L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 Gene3D G3DSA:3.40.50.300 203 269 2.0E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 Gene3D G3DSA:3.40.50.300 4 131 2.0E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 Gene3D G3DSA:3.10.20.30 270 366 9.8E-50 T 09-03-2017 IPR012675 Beta-grasp domain L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 PIRSF PIRSF006641 1 366 7.5E-154 T 09-03-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 L21SP3_RS09385 ed44ceda5199ec2b76d0bc5a09349d5b 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 3.5E-145 T 09-03-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 L21SP3_RS05215 f152152783546244cc4f68ce6d9bc48a 269 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 22 243 2.1E-58 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP3_RS05215 f152152783546244cc4f68ce6d9bc48a 269 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 118 144 1.1E-34 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP3_RS05215 f152152783546244cc4f68ce6d9bc48a 269 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 100 118 1.1E-34 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP3_RS05215 f152152783546244cc4f68ce6d9bc48a 269 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 171 199 1.1E-34 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP3_RS05215 f152152783546244cc4f68ce6d9bc48a 269 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 20 47 1.1E-34 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP3_RS05215 f152152783546244cc4f68ce6d9bc48a 269 ProSitePatterns PS01218 TatC family signature. 171 190 - T 09-03-2017 IPR019820 Sec-independent periplasmic protein translocase, conserved site L21SP3_RS05215 f152152783546244cc4f68ce6d9bc48a 269 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 11 260 18.136 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP3_RS05215 f152152783546244cc4f68ce6d9bc48a 269 Pfam PF00902 Sec-independent protein translocase protein (TatC) 23 238 2.3E-63 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 L21SP3_RS01240 5c0b6391b8c9cdf95b15629d0623c45b 476 Pfam PF08547 Complex I intermediate-associated protein 30 (CIA30) 42 156 2.7E-21 T 09-03-2017 IPR013857 NADH:ubiquinone oxidoreductase intermediate-associated protein 30 Reactome: R-HSA-6799198 L21SP3_RS01240 5c0b6391b8c9cdf95b15629d0623c45b 476 Gene3D G3DSA:2.170.150.20 194 317 3.4E-51 T 09-03-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 L21SP3_RS01240 5c0b6391b8c9cdf95b15629d0623c45b 476 SUPERFAMILY SSF55068 278 472 2.22E-66 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 L21SP3_RS01240 5c0b6391b8c9cdf95b15629d0623c45b 476 Pfam PF01641 SelR domain 197 313 9.8E-44 T 09-03-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 L21SP3_RS01240 5c0b6391b8c9cdf95b15629d0623c45b 476 SUPERFAMILY SSF51316 193 319 2.2E-48 T 09-03-2017 IPR011057 Mss4-like L21SP3_RS01240 5c0b6391b8c9cdf95b15629d0623c45b 476 Gene3D G3DSA:3.30.1060.10 318 472 1.1E-59 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 L21SP3_RS01240 5c0b6391b8c9cdf95b15629d0623c45b 476 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 318 464 4.9E-53 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 L21SP3_RS01240 5c0b6391b8c9cdf95b15629d0623c45b 476 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 317 473 33.792 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 L21SP3_RS01240 5c0b6391b8c9cdf95b15629d0623c45b 476 Pfam PF01625 Peptide methionine sulfoxide reductase 320 469 2.4E-59 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 L21SP3_RS01240 5c0b6391b8c9cdf95b15629d0623c45b 476 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 194 319 4.6E-36 T 09-03-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 L21SP3_RS01240 5c0b6391b8c9cdf95b15629d0623c45b 476 SUPERFAMILY SSF49785 34 192 1.11E-18 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09795 1d0e2bd555907bcfe7cadd8324c7289b 212 Gene3D G3DSA:2.40.50.140 1 53 2.5E-9 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS09795 1d0e2bd555907bcfe7cadd8324c7289b 212 SUPERFAMILY SSF47781 72 138 2.78E-11 T 09-03-2017 IPR010994 RuvA domain 2-like L21SP3_RS09795 1d0e2bd555907bcfe7cadd8324c7289b 212 Gene3D G3DSA:1.10.150.20 74 142 4.6E-16 T 09-03-2017 L21SP3_RS09795 1d0e2bd555907bcfe7cadd8324c7289b 212 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 208 19.518 T 09-03-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 L21SP3_RS09795 1d0e2bd555907bcfe7cadd8324c7289b 212 Pfam PF01330 RuvA N terminal domain 2 54 5.6E-8 T 09-03-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 L21SP3_RS09795 1d0e2bd555907bcfe7cadd8324c7289b 212 Pfam PF14520 Helix-hairpin-helix domain 82 134 1.1E-7 T 09-03-2017 L21SP3_RS00295 f09b44627831082ec40471de8fd7a82c 480 Pfam PF13394 4Fe-4S single cluster domain 159 221 2.9E-5 T 09-03-2017 L21SP3_RS00295 f09b44627831082ec40471de8fd7a82c 480 Pfam PF13186 Iron-sulfur cluster-binding domain 381 421 5.9E-7 T 09-03-2017 IPR023885 4Fe4S-binding SPASM domain L21SP3_RS00295 f09b44627831082ec40471de8fd7a82c 480 SUPERFAMILY SSF102114 153 434 1.06E-49 T 09-03-2017 L21SP3_RS00295 f09b44627831082ec40471de8fd7a82c 480 Gene3D G3DSA:3.20.20.70 152 421 4.1E-49 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS00295 f09b44627831082ec40471de8fd7a82c 480 Pfam PF04055 Radical SAM superfamily 162 292 3.2E-14 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS08385 7d218b492bfed2ecda3d7d8c943dcfe3 245 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 28 9.1E-6 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS08385 7d218b492bfed2ecda3d7d8c943dcfe3 245 SUPERFAMILY SSF54523 9 67 5.26E-12 T 09-03-2017 L21SP3_RS08385 7d218b492bfed2ecda3d7d8c943dcfe3 245 Pfam PF13633 Prokaryotic N-terminal methylation site 7 32 1.0E-5 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS00385 3f7450f33e3542e16cea3de3bfee9a4a 745 Gene3D G3DSA:2.60.120.200 56 237 6.2E-22 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00385 3f7450f33e3542e16cea3de3bfee9a4a 745 Gene3D G3DSA:2.60.120.200 536 692 1.1E-31 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00385 3f7450f33e3542e16cea3de3bfee9a4a 745 SMART SM00560 549 684 0.0027 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS00385 3f7450f33e3542e16cea3de3bfee9a4a 745 Gene3D G3DSA:2.60.40.10 391 449 1.1E-8 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS00385 3f7450f33e3542e16cea3de3bfee9a4a 745 SUPERFAMILY SSF48726 380 450 6.3E-10 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS00385 3f7450f33e3542e16cea3de3bfee9a4a 745 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 66 236 5.3E-14 T 09-03-2017 L21SP3_RS00385 3f7450f33e3542e16cea3de3bfee9a4a 745 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 536 687 1.4E-31 T 09-03-2017 L21SP3_RS00385 3f7450f33e3542e16cea3de3bfee9a4a 745 SUPERFAMILY SSF49899 460 691 3.96E-32 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00385 3f7450f33e3542e16cea3de3bfee9a4a 745 SUPERFAMILY SSF49899 34 237 2.97E-20 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10870 076f3cecef9dbcf8a74be3e2eadb64fa 758 SUPERFAMILY SSF49899 615 755 7.04E-19 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10870 076f3cecef9dbcf8a74be3e2eadb64fa 758 Gene3D G3DSA:2.115.10.20 303 360 2.3E-8 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS10870 076f3cecef9dbcf8a74be3e2eadb64fa 758 SMART SM00640 298 715 5.0E-77 T 09-03-2017 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 L21SP3_RS10870 076f3cecef9dbcf8a74be3e2eadb64fa 758 Gene3D G3DSA:2.60.120.560 611 756 3.2E-15 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal L21SP3_RS10870 076f3cecef9dbcf8a74be3e2eadb64fa 758 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 298 606 6.7E-65 T 09-03-2017 IPR013148 Glycosyl hydrolase family 32, N-terminal L21SP3_RS10870 076f3cecef9dbcf8a74be3e2eadb64fa 758 SUPERFAMILY SSF75005 288 616 3.4E-75 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 Gene3D G3DSA:3.40.50.300 491 643 6.1E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 SMART SM00491 513 646 9.7E-27 T 09-03-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 Gene3D G3DSA:3.40.50.300 31 107 8.9E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 Gene3D G3DSA:3.40.50.300 188 246 8.9E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 SMART SM00487 28 281 0.0014 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 Pfam PF06733 DEAD_2 190 260 2.5E-8 T 09-03-2017 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 SUPERFAMILY SSF52540 605 641 2.84E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 SUPERFAMILY SSF52540 23 124 2.84E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 SUPERFAMILY SSF52540 200 256 2.84E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 SUPERFAMILY SSF52540 616 641 1.56E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 SUPERFAMILY SSF52540 494 585 1.56E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 SMART SM00488 30 285 4.5E-4 T 09-03-2017 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 Pfam PF13307 Helicase C-terminal domain 502 659 7.5E-35 T 09-03-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 L21SP3_RS06710 e875e10c55f8b572223974be39b3c3c5 679 Pfam PF00270 DEAD/DEAH box helicase 47 103 8.0E-6 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 Gene3D G3DSA:3.30.930.10 5 204 6.4E-87 T 09-03-2017 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 Gene3D G3DSA:3.30.930.10 395 469 6.4E-87 T 09-03-2017 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 SUPERFAMILY SSF55826 218 378 1.1E-29 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 Pfam PF04073 Aminoacyl-tRNA editing domain 257 378 2.4E-27 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 Gene3D G3DSA:3.90.960.10 251 394 6.0E-32 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 SUPERFAMILY SSF52954 465 572 1.66E-28 T 09-03-2017 IPR004154 Anticodon-binding L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 SUPERFAMILY SSF55681 10 237 8.04E-86 T 09-03-2017 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 SUPERFAMILY SSF55681 408 479 8.04E-86 T 09-03-2017 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 Gene3D G3DSA:3.40.50.800 471 573 2.4E-28 T 09-03-2017 IPR004154 Anticodon-binding L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 560 5.2E-186 T 09-03-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 569 36.776 T 09-03-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 Pfam PF03129 Anticodon binding domain 477 564 7.3E-19 T 09-03-2017 IPR004154 Anticodon-binding L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 460 2.4E-38 T 09-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 2.7E-11 T 09-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 2.7E-11 T 09-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 2.7E-11 T 09-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 L21SP3_RS01815 8a1347e926031973cf8598350af6f49d 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 2.7E-11 T 09-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 L21SP3_RS01690 16f043a47c332ac5fac28a8fc3149585 1152 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 531 864 2.3E-61 T 09-03-2017 IPR025692 Mechanosensitive ion channel inner membrane domain 1 L21SP3_RS01690 16f043a47c332ac5fac28a8fc3149585 1152 Gene3D G3DSA:3.30.70.100 1035 1121 6.8E-24 T 09-03-2017 L21SP3_RS01690 16f043a47c332ac5fac28a8fc3149585 1152 Pfam PF12795 Mechanosensitive ion channel porin domain 70 301 6.9E-12 T 09-03-2017 IPR024393 Mechanosensitive ion channel MscS, porin domain L21SP3_RS01690 16f043a47c332ac5fac28a8fc3149585 1152 Pfam PF00924 Mechanosensitive ion channel 923 1123 4.7E-57 T 09-03-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 L21SP3_RS01690 16f043a47c332ac5fac28a8fc3149585 1152 SUPERFAMILY SSF50182 966 1031 2.58E-17 T 09-03-2017 IPR010920 LSM domain L21SP3_RS01690 16f043a47c332ac5fac28a8fc3149585 1152 SUPERFAMILY SSF82689 1033 1134 4.84E-28 T 09-03-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 L21SP3_RS01690 16f043a47c332ac5fac28a8fc3149585 1152 Gene3D G3DSA:2.30.30.60 981 1030 4.4E-18 T 09-03-2017 L21SP3_RS07990 a665d8e114357c4c737726b8f5211dfe 483 Gene3D G3DSA:3.40.720.10 31 152 1.2E-41 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS07990 a665d8e114357c4c737726b8f5211dfe 483 Gene3D G3DSA:3.40.720.10 153 343 3.5E-41 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS07990 a665d8e114357c4c737726b8f5211dfe 483 Pfam PF00884 Sulfatase 34 146 1.5E-24 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS07990 a665d8e114357c4c737726b8f5211dfe 483 Pfam PF00884 Sulfatase 153 299 9.5E-23 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS07990 a665d8e114357c4c737726b8f5211dfe 483 ProSitePatterns PS00523 Sulfatases signature 1. 80 92 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS07990 a665d8e114357c4c737726b8f5211dfe 483 SUPERFAMILY SSF53649 395 440 6.25E-106 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS07990 a665d8e114357c4c737726b8f5211dfe 483 SUPERFAMILY SSF53649 32 356 6.25E-106 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS07990 a665d8e114357c4c737726b8f5211dfe 483 Gene3D G3DSA:3.30.1120.10 344 358 1.8E-13 T 09-03-2017 L21SP3_RS07990 a665d8e114357c4c737726b8f5211dfe 483 Gene3D G3DSA:3.30.1120.10 397 446 1.8E-13 T 09-03-2017 L21SP3_RS05975 5cbbc848a339c0b6b5026812f840a11b 1007 Pfam PF00263 Bacterial type II and III secretion system protein 785 954 1.4E-35 T 09-03-2017 IPR004846 Type II/III secretion system GO:0009306 L21SP3_RS05975 5cbbc848a339c0b6b5026812f840a11b 1007 PRINTS PR00811 Bacterial general secretion pathway protein D signature 780 804 8.1E-17 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS05975 5cbbc848a339c0b6b5026812f840a11b 1007 PRINTS PR00811 Bacterial general secretion pathway protein D signature 707 717 8.1E-17 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS05975 5cbbc848a339c0b6b5026812f840a11b 1007 PRINTS PR00811 Bacterial general secretion pathway protein D signature 918 936 8.1E-17 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS05975 5cbbc848a339c0b6b5026812f840a11b 1007 PRINTS PR00811 Bacterial general secretion pathway protein D signature 941 955 8.1E-17 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS05975 5cbbc848a339c0b6b5026812f840a11b 1007 Pfam PF03958 Bacterial type II/III secretion system short domain 606 707 4.5E-12 T 09-03-2017 IPR005644 NolW-like L21SP3_RS05975 5cbbc848a339c0b6b5026812f840a11b 1007 Pfam PF03958 Bacterial type II/III secretion system short domain 405 492 1.5E-6 T 09-03-2017 IPR005644 NolW-like L21SP3_RS08735 a5b9d5315f5ff7b2b704c452bc30a15e 466 Gene3D G3DSA:3.40.720.10 29 142 1.2E-35 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08735 a5b9d5315f5ff7b2b704c452bc30a15e 466 Gene3D G3DSA:3.30.1120.10 400 453 9.5E-18 T 09-03-2017 L21SP3_RS08735 a5b9d5315f5ff7b2b704c452bc30a15e 466 Gene3D G3DSA:3.30.1120.10 346 362 9.5E-18 T 09-03-2017 L21SP3_RS08735 a5b9d5315f5ff7b2b704c452bc30a15e 466 Pfam PF16347 Domain of unknown function (DUF4976) 393 442 3.5E-7 T 09-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 L21SP3_RS08735 a5b9d5315f5ff7b2b704c452bc30a15e 466 SUPERFAMILY SSF53649 398 443 1.8E-98 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS08735 a5b9d5315f5ff7b2b704c452bc30a15e 466 SUPERFAMILY SSF53649 30 360 1.8E-98 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS08735 a5b9d5315f5ff7b2b704c452bc30a15e 466 Gene3D G3DSA:3.40.720.10 143 345 2.5E-42 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08735 a5b9d5315f5ff7b2b704c452bc30a15e 466 Pfam PF00884 Sulfatase 32 136 7.3E-22 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS08735 a5b9d5315f5ff7b2b704c452bc30a15e 466 Pfam PF00884 Sulfatase 153 298 1.2E-17 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS10890 105c59465cfcafa32cc9c7cfae9bb3d4 707 SUPERFAMILY SSF48726 351 423 7.41E-8 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS10890 105c59465cfcafa32cc9c7cfae9bb3d4 707 Pfam PF00047 Immunoglobulin domain 370 416 8.3E-5 T 09-03-2017 IPR013151 Immunoglobulin L21SP3_RS10890 105c59465cfcafa32cc9c7cfae9bb3d4 707 SUPERFAMILY SSF49899 429 652 1.25E-18 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10890 105c59465cfcafa32cc9c7cfae9bb3d4 707 Gene3D G3DSA:2.60.40.10 340 418 4.3E-7 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS10890 105c59465cfcafa32cc9c7cfae9bb3d4 707 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 490 648 1.0E-16 T 09-03-2017 L21SP3_RS10890 105c59465cfcafa32cc9c7cfae9bb3d4 707 Gene3D G3DSA:2.60.120.200 478 650 2.0E-18 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS06455 b2e05c4e675335a2252015b4ad3d901a 397 SUPERFAMILY SSF81606 26 234 2.22E-11 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP3_RS06455 b2e05c4e675335a2252015b4ad3d901a 397 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 37 233 2.9E-16 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP3_RS06455 b2e05c4e675335a2252015b4ad3d901a 397 Gene3D G3DSA:3.60.40.10 145 233 2.6E-5 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP3_RS06455 b2e05c4e675335a2252015b4ad3d901a 397 SMART SM00331 9 233 4.1E-4 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP3_RS02245 ea98f8454c54309ec5ca65fe721fdec9 330 Pfam PF13936 Helix-turn-helix domain 3 45 4.9E-14 T 09-03-2017 IPR025246 Transposase IS30-like HTH domain L21SP3_RS02245 ea98f8454c54309ec5ca65fe721fdec9 330 Pfam PF00665 Integrase core domain 178 280 2.2E-12 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS02245 ea98f8454c54309ec5ca65fe721fdec9 330 ProSitePatterns PS01043 Transposases, IS30 family, signature. 268 284 - T 09-03-2017 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 L21SP3_RS02245 ea98f8454c54309ec5ca65fe721fdec9 330 SUPERFAMILY SSF53098 175 321 2.28E-25 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS02245 ea98f8454c54309ec5ca65fe721fdec9 330 Gene3D G3DSA:3.30.420.10 176 322 8.5E-14 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS09495 ea98f8454c54309ec5ca65fe721fdec9 330 Pfam PF13936 Helix-turn-helix domain 3 45 4.9E-14 T 09-03-2017 IPR025246 Transposase IS30-like HTH domain L21SP3_RS09495 ea98f8454c54309ec5ca65fe721fdec9 330 Pfam PF00665 Integrase core domain 178 280 2.2E-12 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS09495 ea98f8454c54309ec5ca65fe721fdec9 330 ProSitePatterns PS01043 Transposases, IS30 family, signature. 268 284 - T 09-03-2017 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 L21SP3_RS09495 ea98f8454c54309ec5ca65fe721fdec9 330 SUPERFAMILY SSF53098 175 321 2.28E-25 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS09495 ea98f8454c54309ec5ca65fe721fdec9 330 Gene3D G3DSA:3.30.420.10 176 322 8.5E-14 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS02490 8fe35ccba6b870abdbdac44ec12cb76b 223 Gene3D G3DSA:3.40.50.300 3 220 2.4E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02490 8fe35ccba6b870abdbdac44ec12cb76b 223 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 218 3.1E-70 T 09-03-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 L21SP3_RS02490 8fe35ccba6b870abdbdac44ec12cb76b 223 SUPERFAMILY SSF52540 3 222 1.38E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02490 8fe35ccba6b870abdbdac44ec12cb76b 223 Hamap MF_00238 Cytidylate kinase [cmk]. 4 223 31.425 T 09-03-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 L21SP3_RS02490 8fe35ccba6b870abdbdac44ec12cb76b 223 Pfam PF02224 Cytidylate kinase 6 220 8.8E-70 T 09-03-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 L21SP3_RS01785 47663ef4b023d500eb604efb8d1a19f6 144 Gene3D G3DSA:3.40.1350.10 34 143 7.2E-23 T 09-03-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 L21SP3_RS01785 47663ef4b023d500eb604efb8d1a19f6 144 Hamap MF_00048 UPF0102 protein YraN [yraN]. 28 139 15.778 T 09-03-2017 IPR003509 Uncharacterised protein family UPF0102 L21SP3_RS01785 47663ef4b023d500eb604efb8d1a19f6 144 Pfam PF02021 Uncharacterised protein family UPF0102 35 126 8.3E-19 T 09-03-2017 IPR003509 Uncharacterised protein family UPF0102 L21SP3_RS01785 47663ef4b023d500eb604efb8d1a19f6 144 SUPERFAMILY SSF52980 33 130 2.41E-12 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 L21SP3_RS00355 45cf68a51776e0b9ecc3a844be0e4555 461 Gene3D G3DSA:1.10.357.20 275 460 1.5E-37 T 09-03-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 L21SP3_RS00355 45cf68a51776e0b9ecc3a844be0e4555 461 TIGRFAM TIGR00400 mgtE: magnesium transporter 8 460 1.3E-91 T 09-03-2017 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 L21SP3_RS00355 45cf68a51776e0b9ecc3a844be0e4555 461 SUPERFAMILY SSF54631 136 267 1.07E-19 T 09-03-2017 L21SP3_RS00355 45cf68a51776e0b9ecc3a844be0e4555 461 Gene3D G3DSA:1.25.60.10 4 127 1.6E-25 T 09-03-2017 L21SP3_RS00355 45cf68a51776e0b9ecc3a844be0e4555 461 Gene3D G3DSA:3.10.580.10 128 260 4.7E-17 T 09-03-2017 L21SP3_RS00355 45cf68a51776e0b9ecc3a844be0e4555 461 Pfam PF01769 Divalent cation transporter 321 453 7.9E-22 T 09-03-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 L21SP3_RS00355 45cf68a51776e0b9ecc3a844be0e4555 461 SMART SM00924 33 136 1.7E-23 T 09-03-2017 IPR006668 Magnesium transporter, MgtE intracellular domain L21SP3_RS00355 45cf68a51776e0b9ecc3a844be0e4555 461 SUPERFAMILY SSF158791 8 133 2.09E-25 T 09-03-2017 L21SP3_RS00355 45cf68a51776e0b9ecc3a844be0e4555 461 Pfam PF03448 MgtE intracellular N domain 36 134 8.0E-22 T 09-03-2017 IPR006668 Magnesium transporter, MgtE intracellular domain L21SP3_RS00355 45cf68a51776e0b9ecc3a844be0e4555 461 SUPERFAMILY SSF161093 276 460 3.66E-33 T 09-03-2017 L21SP3_RS09645 0384466f6b383f9a5b03619abd567384 150 Pfam PF04074 Domain of unknown function (DUF386) 1 146 2.3E-48 T 09-03-2017 IPR004375 YhcH/YjgK/YiaL family L21SP3_RS09645 0384466f6b383f9a5b03619abd567384 150 TIGRFAM TIGR00022 TIGR00022: YhcH/YjgK/YiaL family protein 1 148 8.1E-34 T 09-03-2017 IPR004375 YhcH/YjgK/YiaL family L21SP3_RS09645 0384466f6b383f9a5b03619abd567384 150 SUPERFAMILY SSF51197 1 148 3.02E-41 T 09-03-2017 L21SP3_RS09645 0384466f6b383f9a5b03619abd567384 150 Gene3D G3DSA:2.60.120.370 1 148 6.2E-49 T 09-03-2017 IPR004375 YhcH/YjgK/YiaL family L21SP3_RS08640 2cdc544ce02addb9ba6fa4a2e85ff9d0 378 Gene3D G3DSA:3.40.50.720 98 256 7.9E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS08640 2cdc544ce02addb9ba6fa4a2e85ff9d0 378 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 255 2.7E-35 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 L21SP3_RS08640 2cdc544ce02addb9ba6fa4a2e85ff9d0 378 SUPERFAMILY SSF51735 91 256 4.41E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS08640 2cdc544ce02addb9ba6fa4a2e85ff9d0 378 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 9 277 2.4E-11 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 L21SP3_RS08640 2cdc544ce02addb9ba6fa4a2e85ff9d0 378 Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. 1 362 38.504 T 09-03-2017 IPR020921 Erythronate-4-phosphate dehydrogenase GO:0005737|GO:0008615|GO:0033711|GO:0055114 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 L21SP3_RS08640 2cdc544ce02addb9ba6fa4a2e85ff9d0 378 SUPERFAMILY SSF52283 5 102 4.13E-12 T 09-03-2017 L21SP3_RS08640 2cdc544ce02addb9ba6fa4a2e85ff9d0 378 Gene3D G3DSA:3.40.50.720 1 97 3.0E-17 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS08640 2cdc544ce02addb9ba6fa4a2e85ff9d0 378 Pfam PF11890 Domain of unknown function (DUF3410) 288 358 4.9E-15 T 09-03-2017 IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain GO:0046983 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 L21SP3_RS05615 7ad91cda25801ff6408e54520010893d 141 Gene3D G3DSA:3.30.70.260 66 126 3.8E-7 T 09-03-2017 L21SP3_RS05615 7ad91cda25801ff6408e54520010893d 141 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 6 54 0.002 T 09-03-2017 L21SP3_RS05615 7ad91cda25801ff6408e54520010893d 141 SUPERFAMILY SSF55021 1 67 2.8E-15 T 09-03-2017 L21SP3_RS05615 7ad91cda25801ff6408e54520010893d 141 SUPERFAMILY SSF55021 71 136 1.27E-12 T 09-03-2017 L21SP3_RS05615 7ad91cda25801ff6408e54520010893d 141 Gene3D G3DSA:3.30.70.260 1 61 2.3E-11 T 09-03-2017 L21SP3_RS05615 7ad91cda25801ff6408e54520010893d 141 Pfam PF01842 ACT domain 5 54 2.1E-7 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 L21SP3_RS10440 ed072ff3e54d9c166f5b9e5906bbbf7d 586 SUPERFAMILY SSF53098 160 579 2.65E-11 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS10440 ed072ff3e54d9c166f5b9e5906bbbf7d 586 Pfam PF01609 Transposase DDE domain 208 506 7.2E-19 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS11080 ed072ff3e54d9c166f5b9e5906bbbf7d 586 SUPERFAMILY SSF53098 160 579 2.65E-11 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS11080 ed072ff3e54d9c166f5b9e5906bbbf7d 586 Pfam PF01609 Transposase DDE domain 208 506 7.2E-19 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS06150 a46eab5fd6ab0c7d695244ce0acc97a1 179 Pfam PF00281 Ribosomal protein L5 24 80 9.7E-25 T 09-03-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06150 a46eab5fd6ab0c7d695244ce0acc97a1 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 09-03-2017 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06150 a46eab5fd6ab0c7d695244ce0acc97a1 179 SUPERFAMILY SSF55282 3 179 5.89E-69 T 09-03-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06150 a46eab5fd6ab0c7d695244ce0acc97a1 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 7.5E-35 T 09-03-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06150 a46eab5fd6ab0c7d695244ce0acc97a1 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 40.123 T 09-03-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06150 a46eab5fd6ab0c7d695244ce0acc97a1 179 Gene3D G3DSA:3.30.1440.10 1 179 2.9E-68 T 09-03-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06150 a46eab5fd6ab0c7d695244ce0acc97a1 179 PIRSF PIRSF002161 1 179 6.5E-63 T 09-03-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS03990 a9494e608dafc048283622d10935f603 851 Pfam PF00343 Carbohydrate phosphorylase 121 186 1.1E-8 T 09-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 L21SP3_RS03990 a9494e608dafc048283622d10935f603 851 Pfam PF00343 Carbohydrate phosphorylase 242 620 9.0E-25 T 09-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 L21SP3_RS03990 a9494e608dafc048283622d10935f603 851 PIRSF PIRSF000460 1 795 4.3E-258 T 09-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 L21SP3_RS03990 a9494e608dafc048283622d10935f603 851 Pfam PF11897 Protein of unknown function (DUF3417) 13 119 6.3E-32 T 09-03-2017 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 L21SP3_RS03990 a9494e608dafc048283622d10935f603 851 Gene3D G3DSA:3.40.50.2000 25 416 1.5E-78 T 09-03-2017 L21SP3_RS03990 a9494e608dafc048283622d10935f603 851 SUPERFAMILY SSF53756 7 729 9.03E-194 T 09-03-2017 L21SP3_RS03990 a9494e608dafc048283622d10935f603 851 Gene3D G3DSA:3.40.50.2000 417 710 4.9E-76 T 09-03-2017 L21SP3_RS03990 a9494e608dafc048283622d10935f603 851 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 106 709 1.0E-244 T 09-03-2017 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 L21SP3_RS06890 cd362eac3abfd9864a6ed26200295cc7 245 SUPERFAMILY SSF58014 46 138 4.18E-23 T 09-03-2017 L21SP3_RS06890 cd362eac3abfd9864a6ed26200295cc7 245 Gene3D G3DSA:2.30.22.10 138 194 2.7E-21 T 09-03-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 L21SP3_RS06890 cd362eac3abfd9864a6ed26200295cc7 245 Hamap MF_01151 Protein GrpE [grpE]. 3 194 19.083 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 L21SP3_RS06890 cd362eac3abfd9864a6ed26200295cc7 245 ProSitePatterns PS01071 grpE protein signature. 149 192 - T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 L21SP3_RS06890 cd362eac3abfd9864a6ed26200295cc7 245 Gene3D G3DSA:3.90.20.20 40 135 1.0E-25 T 09-03-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 L21SP3_RS06890 cd362eac3abfd9864a6ed26200295cc7 245 PRINTS PR00773 GrpE protein signature 64 80 1.1E-22 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 L21SP3_RS06890 cd362eac3abfd9864a6ed26200295cc7 245 PRINTS PR00773 GrpE protein signature 92 107 1.1E-22 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 L21SP3_RS06890 cd362eac3abfd9864a6ed26200295cc7 245 PRINTS PR00773 GrpE protein signature 146 161 1.1E-22 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 L21SP3_RS06890 cd362eac3abfd9864a6ed26200295cc7 245 PRINTS PR00773 GrpE protein signature 173 192 1.1E-22 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 L21SP3_RS06890 cd362eac3abfd9864a6ed26200295cc7 245 SUPERFAMILY SSF51064 140 194 8.76E-16 T 09-03-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 L21SP3_RS06890 cd362eac3abfd9864a6ed26200295cc7 245 Pfam PF01025 GrpE 33 194 7.7E-48 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 L21SP3_RS08825 c72791004db4429ce69a1412efe5e71f 160 Pfam PF00694 Aconitase C-terminal domain 40 105 3.6E-19 T 09-03-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS08825 c72791004db4429ce69a1412efe5e71f 160 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 1 160 32.013 T 09-03-2017 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 L21SP3_RS08825 c72791004db4429ce69a1412efe5e71f 160 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 9 158 3.1E-56 T 09-03-2017 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 L21SP3_RS08825 c72791004db4429ce69a1412efe5e71f 160 SUPERFAMILY SSF52016 9 159 6.08E-48 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel L21SP3_RS08825 c72791004db4429ce69a1412efe5e71f 160 Gene3D G3DSA:3.20.19.10 8 159 3.1E-36 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel L21SP3_RS01620 b9b4040fb9b03c17215289816ada66e0 665 ProSitePatterns PS00149 Sulfatases signature 2. 147 157 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS01620 b9b4040fb9b03c17215289816ada66e0 665 ProSitePatterns PS00523 Sulfatases signature 1. 99 111 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS01620 b9b4040fb9b03c17215289816ada66e0 665 Gene3D G3DSA:3.30.1120.10 435 488 9.9E-17 T 09-03-2017 L21SP3_RS01620 b9b4040fb9b03c17215289816ada66e0 665 SUPERFAMILY SSF53649 52 489 1.05E-112 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS01620 b9b4040fb9b03c17215289816ada66e0 665 Gene3D G3DSA:3.40.720.10 50 418 3.7E-96 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS01620 b9b4040fb9b03c17215289816ada66e0 665 Pfam PF00884 Sulfatase 53 397 3.0E-60 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS05505 998988dde71d1e64645e82a8ea118af0 347 Pfam PF00534 Glycosyl transferases group 1 162 322 3.0E-39 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS05505 998988dde71d1e64645e82a8ea118af0 347 Pfam PF13439 Glycosyltransferase Family 4 13 159 5.7E-8 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 L21SP3_RS05505 998988dde71d1e64645e82a8ea118af0 347 SUPERFAMILY SSF53756 3 345 2.47E-66 T 09-03-2017 L21SP3_RS05505 998988dde71d1e64645e82a8ea118af0 347 Gene3D G3DSA:3.40.50.2000 168 322 2.3E-25 T 09-03-2017 L21SP3_RS10125 68d4cffe542852cf7c81e364333755f9 145 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 9 137 4.8E-21 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP3_RS10125 68d4cffe542852cf7c81e364333755f9 145 Gene3D G3DSA:3.40.50.270 7 140 1.1E-45 T 09-03-2017 L21SP3_RS10125 68d4cffe542852cf7c81e364333755f9 145 SUPERFAMILY SSF52788 7 140 2.09E-41 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP3_RS10125 68d4cffe542852cf7c81e364333755f9 145 SMART SM00226 7 139 3.8E-38 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP3_RS07675 4b08619809ead68ab83797b5acd862bf 169 SUPERFAMILY SSF47240 1 161 1.86E-61 T 09-03-2017 IPR009078 Ferritin-like superfamily L21SP3_RS07675 4b08619809ead68ab83797b5acd862bf 169 Pfam PF00210 Ferritin-like domain 8 143 1.6E-45 T 09-03-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 L21SP3_RS07675 4b08619809ead68ab83797b5acd862bf 169 Gene3D G3DSA:1.20.1260.10 1 164 2.7E-64 T 09-03-2017 IPR012347 Ferritin-related L21SP3_RS00585 d7e970092bb1a3dbbdd012b642afd2d7 299 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 285 15.785 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 L21SP3_RS00585 d7e970092bb1a3dbbdd012b642afd2d7 299 Pfam PF01867 CRISPR associated protein Cas1 7 233 5.1E-23 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 L21SP3_RS00585 d7e970092bb1a3dbbdd012b642afd2d7 299 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 11 237 2.1E-22 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 L21SP3_RS00585 d7e970092bb1a3dbbdd012b642afd2d7 299 TIGRFAM TIGR03639 cas1_NMENI: CRISPR-associated endonuclease Cas1, subtype II/NMENI 2 283 1.3E-74 T 09-03-2017 IPR019855 CRISPR-associated protein Cas1, NMENI subtype GO:0004520|GO:0043571|GO:0046872 L21SP3_RS05050 decd33b14190fa0fcf6423ae630ea394 212 Pfam PF15514 Restriction endonuclease ThaI 12 211 6.2E-82 T 09-03-2017 IPR029128 Restriction endonuclease ThaI L21SP3_RS02890 330fd93ff548077e1f480e2fae3f27ca 253 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 16 248 35.43 T 09-03-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 L21SP3_RS02890 330fd93ff548077e1f480e2fae3f27ca 253 Gene3D G3DSA:3.20.20.70 15 247 5.5E-81 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS02890 330fd93ff548077e1f480e2fae3f27ca 253 Pfam PF00977 Histidine biosynthesis protein 17 241 8.6E-77 T 09-03-2017 IPR006062 Histidine biosynthesis GO:0000105 L21SP3_RS02890 330fd93ff548077e1f480e2fae3f27ca 253 SUPERFAMILY SSF51366 15 247 8.75E-70 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP3_RS02890 330fd93ff548077e1f480e2fae3f27ca 253 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 17 243 2.2E-82 T 09-03-2017 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 PRINTS PR00344 Bacterial sensor protein C-terminal signature 681 691 1.6E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 PRINTS PR00344 Bacterial sensor protein C-terminal signature 696 714 1.6E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 PRINTS PR00344 Bacterial sensor protein C-terminal signature 720 733 1.6E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 PRINTS PR00344 Bacterial sensor protein C-terminal signature 663 677 1.6E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 Pfam PF13188 PAS domain 385 434 1.7E-5 T 09-03-2017 IPR000014 PAS domain L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 SMART SM00388 516 583 1.2E-7 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 SUPERFAMILY SSF47384 501 583 1.96E-14 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 385 500 5.3E-7 T 09-03-2017 IPR000014 PAS domain L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 Gene3D G3DSA:3.30.450.20 370 494 2.5E-15 T 09-03-2017 L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 Gene3D G3DSA:1.10.287.130 508 579 1.3E-7 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 625 733 2.5E-22 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 SUPERFAMILY SSF55874 573 734 6.16E-40 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 Gene3D G3DSA:3.30.565.10 584 734 3.6E-40 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 SMART SM00091 384 451 0.0013 T 09-03-2017 IPR000014 PAS domain L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 SUPERFAMILY SSF55785 370 494 1.92E-13 T 09-03-2017 IPR000014 PAS domain L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 SMART SM00387 624 735 5.6E-30 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11100 07cd0e1c1b5ef23e3898a267875436c8 735 Pfam PF00512 His Kinase A (phospho-acceptor) domain 517 582 1.1E-7 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS07180 241e5eff82d82092694f0e7ff912d728 682 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 155 8.7E-14 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP3_RS07180 241e5eff82d82092694f0e7ff912d728 682 Gene3D G3DSA:3.40.50.300 3 168 4.4E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07180 241e5eff82d82092694f0e7ff912d728 682 Pfam PF07670 Nucleoside recognition 352 442 1.2E-12 T 09-03-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 L21SP3_RS07180 241e5eff82d82092694f0e7ff912d728 682 Pfam PF07670 Nucleoside recognition 513 653 6.3E-21 T 09-03-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 L21SP3_RS07180 241e5eff82d82092694f0e7ff912d728 682 SUPERFAMILY SSF52540 4 164 9.74E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07180 241e5eff82d82092694f0e7ff912d728 682 Pfam PF07664 Ferrous iron transport protein B C terminus 456 508 4.2E-21 T 09-03-2017 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 L21SP3_RS07180 241e5eff82d82092694f0e7ff912d728 682 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 1.7E-7 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS07180 241e5eff82d82092694f0e7ff912d728 682 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 54 69 1.7E-7 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS07180 241e5eff82d82092694f0e7ff912d728 682 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 1.7E-7 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS07180 241e5eff82d82092694f0e7ff912d728 682 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 649 1.4E-174 T 09-03-2017 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 L21SP3_RS07180 241e5eff82d82092694f0e7ff912d728 682 Pfam PF02421 Ferrous iron transport protein B 4 159 2.4E-59 T 09-03-2017 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 L21SP3_RS03885 3b939666f77157afeafb995b94214b5c 377 SUPERFAMILY SSF53822 6 263 2.69E-29 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS03885 3b939666f77157afeafb995b94214b5c 377 Gene3D G3DSA:1.10.10.60 323 373 4.2E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS03885 3b939666f77157afeafb995b94214b5c 377 Gene3D G3DSA:3.40.50.2300 91 264 7.5E-26 T 09-03-2017 L21SP3_RS03885 3b939666f77157afeafb995b94214b5c 377 SMART SM00342 287 370 1.3E-13 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS03885 3b939666f77157afeafb995b94214b5c 377 Pfam PF12833 Helix-turn-helix domain 295 372 1.8E-19 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS03885 3b939666f77157afeafb995b94214b5c 377 SUPERFAMILY SSF46689 324 373 2.06E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS03885 3b939666f77157afeafb995b94214b5c 377 Pfam PF13377 Periplasmic binding protein-like domain 104 263 3.4E-24 T 09-03-2017 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 Gene3D G3DSA:3.20.20.10 37 266 4.3E-70 T 09-03-2017 IPR029066 PLP-binding barrel L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 285 401 6.3E-19 T 09-03-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 SUPERFAMILY SSF50621 255 424 1.51E-51 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 425 38.18 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 226 241 - T 09-03-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 382 395 8.9E-21 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 57 75 8.9E-21 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 77 89 8.9E-21 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 270 289 8.9E-21 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 190 203 8.9E-21 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 PRINTS PR01181 Diaminopimelate decarboxylase signature 392 414 1.5E-28 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 PRINTS PR01181 Diaminopimelate decarboxylase signature 75 92 1.5E-28 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 PRINTS PR01181 Diaminopimelate decarboxylase signature 164 173 1.5E-28 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 PRINTS PR01181 Diaminopimelate decarboxylase signature 298 316 1.5E-28 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 Gene3D G3DSA:2.40.37.10 267 424 8.2E-48 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 SUPERFAMILY SSF51419 26 282 2.88E-68 T 09-03-2017 IPR029066 PLP-binding barrel L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 6 424 1.5E-137 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS03010 915fd0198bfcfb94981b2411db68f9cb 425 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 40 281 1.5E-56 T 09-03-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 L21SP3_RS00990 4452af8ed001ae589d4adf2a0f8d2539 62 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 16.318 T 09-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS00990 4452af8ed001ae589d4adf2a0f8d2539 62 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 3 51 1.1E-18 T 09-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS00990 4452af8ed001ae589d4adf2a0f8d2539 62 SUPERFAMILY SSF57829 3 55 7.94E-17 T 09-03-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 L21SP3_RS00990 4452af8ed001ae589d4adf2a0f8d2539 62 Pfam PF01783 Ribosomal L32p protein family 3 51 8.9E-20 T 09-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS10605 e836fd6161617d9f86df0d82667e0e7a 305 Pfam PF00175 Oxidoreductase NAD-binding domain 139 246 6.1E-9 T 09-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 L21SP3_RS10605 e836fd6161617d9f86df0d82667e0e7a 305 Gene3D G3DSA:2.10.240.10 261 303 7.7E-14 T 09-03-2017 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain L21SP3_RS10605 e836fd6161617d9f86df0d82667e0e7a 305 Gene3D G3DSA:2.40.30.10 15 125 5.7E-12 T 09-03-2017 L21SP3_RS10605 e836fd6161617d9f86df0d82667e0e7a 305 SUPERFAMILY SSF52343 122 302 6.94E-30 T 09-03-2017 L21SP3_RS10605 e836fd6161617d9f86df0d82667e0e7a 305 Gene3D G3DSA:3.40.50.80 129 259 1.1E-22 T 09-03-2017 L21SP3_RS10605 e836fd6161617d9f86df0d82667e0e7a 305 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 261 302 2.1E-14 T 09-03-2017 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain L21SP3_RS10605 e836fd6161617d9f86df0d82667e0e7a 305 SUPERFAMILY SSF63380 41 127 1.79E-7 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 L21SP3_RS00440 b11daa04217ea7d69e65ef62159f01b3 145 SUPERFAMILY SSF141734 15 122 2.75E-44 T 09-03-2017 L21SP3_RS00440 b11daa04217ea7d69e65ef62159f01b3 145 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 62 114 1.0E-14 T 09-03-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 L21SP3_RS00440 b11daa04217ea7d69e65ef62159f01b3 145 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 38 111 7.9E-34 T 09-03-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 L21SP3_RS00440 b11daa04217ea7d69e65ef62159f01b3 145 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 12 115 29.501 T 09-03-2017 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 L21SP3_RS08340 8bf2d0b56897f2306c1f9c017281c450 255 PRINTS PR00813 Bacterial general secretion pathway protein G signature 28 53 1.8E-7 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS08340 8bf2d0b56897f2306c1f9c017281c450 255 PRINTS PR00813 Bacterial general secretion pathway protein G signature 64 82 1.8E-7 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS08340 8bf2d0b56897f2306c1f9c017281c450 255 Pfam PF13633 Prokaryotic N-terminal methylation site 27 52 1.2E-9 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS08340 8bf2d0b56897f2306c1f9c017281c450 255 Pfam PF07596 Protein of unknown function (DUF1559) 54 90 3.2E-4 T 09-03-2017 IPR011453 Protein of unknown function DUF1559 L21SP3_RS08340 8bf2d0b56897f2306c1f9c017281c450 255 Gene3D G3DSA:3.30.700.10 29 83 2.3E-7 T 09-03-2017 L21SP3_RS08340 8bf2d0b56897f2306c1f9c017281c450 255 SUPERFAMILY SSF54523 29 111 1.18E-15 T 09-03-2017 L21SP3_RS08340 8bf2d0b56897f2306c1f9c017281c450 255 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 212 227 3.5E-7 T 09-03-2017 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP3_RS08340 8bf2d0b56897f2306c1f9c017281c450 255 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 27 48 4.4E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS08340 8bf2d0b56897f2306c1f9c017281c450 255 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 27 47 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS08415 618022fb89413a2abe41f9b2c1011a9c 266 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 7 28 5.5E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS08415 618022fb89413a2abe41f9b2c1011a9c 266 Pfam PF07596 Protein of unknown function (DUF1559) 36 105 1.1E-5 T 09-03-2017 IPR011453 Protein of unknown function DUF1559 L21SP3_RS08415 618022fb89413a2abe41f9b2c1011a9c 266 Gene3D G3DSA:3.30.700.10 11 64 6.4E-5 T 09-03-2017 L21SP3_RS08415 618022fb89413a2abe41f9b2c1011a9c 266 SUPERFAMILY SSF54523 11 109 1.26E-15 T 09-03-2017 L21SP3_RS08415 618022fb89413a2abe41f9b2c1011a9c 266 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 208 223 9.3E-5 T 09-03-2017 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP3_RS08415 618022fb89413a2abe41f9b2c1011a9c 266 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 31 3.4E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS08415 618022fb89413a2abe41f9b2c1011a9c 266 PRINTS PR00813 Bacterial general secretion pathway protein G signature 10 35 4.3E-8 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS08415 618022fb89413a2abe41f9b2c1011a9c 266 PRINTS PR00813 Bacterial general secretion pathway protein G signature 46 64 4.3E-8 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS06525 ad0586b803fa9c3a6c72a2492103a626 372 SUPERFAMILY SSF102405 83 289 1.34E-35 T 09-03-2017 L21SP3_RS06525 ad0586b803fa9c3a6c72a2492103a626 372 Pfam PF02481 DNA recombination-mediator protein A 74 281 7.5E-72 T 09-03-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 L21SP3_RS06525 ad0586b803fa9c3a6c72a2492103a626 372 Gene3D G3DSA:3.40.50.450 117 261 5.3E-11 T 09-03-2017 L21SP3_RS06525 ad0586b803fa9c3a6c72a2492103a626 372 Pfam PF14520 Helix-hairpin-helix domain 11 60 2.2E-7 T 09-03-2017 L21SP3_RS06525 ad0586b803fa9c3a6c72a2492103a626 372 SUPERFAMILY SSF47781 5 63 5.93E-10 T 09-03-2017 IPR010994 RuvA domain 2-like L21SP3_RS06525 ad0586b803fa9c3a6c72a2492103a626 372 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 290 4.4E-66 T 09-03-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 L21SP3_RS06525 ad0586b803fa9c3a6c72a2492103a626 372 Gene3D G3DSA:1.10.150.20 12 62 4.4E-9 T 09-03-2017 L21SP3_RS08005 3fc17e5892440cfb1a51724d76f84be8 387 SUPERFAMILY SSF63446 333 383 6.15E-6 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS08005 3fc17e5892440cfb1a51724d76f84be8 387 Gene3D G3DSA:1.10.1330.10 334 385 4.6E-7 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS08005 3fc17e5892440cfb1a51724d76f84be8 387 ProSitePatterns PS00018 EF-hand calcium-binding domain. 337 349 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS08005 3fc17e5892440cfb1a51724d76f84be8 387 Gene3D G3DSA:2.60.120.260 70 221 1.6E-4 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS05180 7a030885333935d9509af50fd68b9db8 359 Gene3D G3DSA:3.30.70.560 4 151 3.6E-51 T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 L21SP3_RS05180 7a030885333935d9509af50fd68b9db8 359 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 134 1.5E-35 T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 L21SP3_RS05180 7a030885333935d9509af50fd68b9db8 359 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 134 1.6E-41 T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 L21SP3_RS05180 7a030885333935d9509af50fd68b9db8 359 Pfam PF01712 Deoxynucleoside kinase 167 355 4.6E-24 T 09-03-2017 IPR031314 Deoxynucleoside kinase domain L21SP3_RS05180 7a030885333935d9509af50fd68b9db8 359 SUPERFAMILY SSF55083 3 153 1.57E-47 T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 L21SP3_RS05180 7a030885333935d9509af50fd68b9db8 359 Gene3D G3DSA:3.40.50.300 159 341 3.9E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05180 7a030885333935d9509af50fd68b9db8 359 SUPERFAMILY SSF52540 163 341 8.63E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02845 2b35248321eff6b73dd4b35562e66597 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.9E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02845 2b35248321eff6b73dd4b35562e66597 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 230 250 1.9E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02845 2b35248321eff6b73dd4b35562e66597 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.9E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02845 2b35248321eff6b73dd4b35562e66597 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.9E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02845 2b35248321eff6b73dd4b35562e66597 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.9E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02845 2b35248321eff6b73dd4b35562e66597 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 1.9E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02845 2b35248321eff6b73dd4b35562e66597 272 Gene3D G3DSA:3.40.50.720 2 267 3.4E-68 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS02845 2b35248321eff6b73dd4b35562e66597 272 SUPERFAMILY SSF51735 10 268 9.49E-67 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS02845 2b35248321eff6b73dd4b35562e66597 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 1.1E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02845 2b35248321eff6b73dd4b35562e66597 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 1.1E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02845 2b35248321eff6b73dd4b35562e66597 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.1E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02845 2b35248321eff6b73dd4b35562e66597 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 267 1.1E-46 T 09-03-2017 L21SP3_RS02845 2b35248321eff6b73dd4b35562e66597 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 L21SP3_RS08770 3a47d27b80db368ee12182ee0e846ee9 259 Pfam PF06300 Tsp45I type II restriction enzyme 2 259 3.9E-120 T 09-03-2017 IPR010443 Restriction endonuclease, type II, Tsp45I L21SP3_RS07265 2579e479d49fdfb022b0ea2cc4304dd0 357 Pfam PF00589 Phage integrase family 190 357 4.4E-24 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP3_RS07265 2579e479d49fdfb022b0ea2cc4304dd0 357 Gene3D G3DSA:1.10.443.10 185 357 1.9E-26 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP3_RS07265 2579e479d49fdfb022b0ea2cc4304dd0 357 Gene3D G3DSA:1.10.150.130 95 173 3.2E-6 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal L21SP3_RS07265 2579e479d49fdfb022b0ea2cc4304dd0 357 SUPERFAMILY SSF56349 79 357 5.59E-36 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 L21SP3_RS04265 4ec0f741256cd7ae4af9db96530a7b2c 358 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 174 188 - T 09-03-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS04265 4ec0f741256cd7ae4af9db96530a7b2c 358 SMART SM00363 55 119 7.4E-7 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS04265 4ec0f741256cd7ae4af9db96530a7b2c 358 SUPERFAMILY SSF55174 55 141 1.33E-10 T 09-03-2017 L21SP3_RS04265 4ec0f741256cd7ae4af9db96530a7b2c 358 SUPERFAMILY SSF55120 112 355 9.87E-71 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS04265 4ec0f741256cd7ae4af9db96530a7b2c 358 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 55 355 1.0E-86 T 09-03-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS04265 4ec0f741256cd7ae4af9db96530a7b2c 358 Gene3D G3DSA:3.10.290.10 56 103 2.3E-8 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS04265 4ec0f741256cd7ae4af9db96530a7b2c 358 Pfam PF01479 S4 domain 55 101 2.0E-7 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS04265 4ec0f741256cd7ae4af9db96530a7b2c 358 Pfam PF00849 RNA pseudouridylate synthase 128 283 3.9E-36 T 09-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS04955 0109c3dac0801948d4ba529aae932f27 1126 SMART SM00408 741 806 8.7E-7 T 09-03-2017 IPR003598 Immunoglobulin subtype 2 L21SP3_RS04955 0109c3dac0801948d4ba529aae932f27 1126 SUPERFAMILY SSF49899 813 1027 2.24E-27 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04955 0109c3dac0801948d4ba529aae932f27 1126 Gene3D G3DSA:2.60.120.200 814 1027 1.4E-26 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04955 0109c3dac0801948d4ba529aae932f27 1126 Pfam PF13927 Immunoglobulin domain 728 803 6.5E-12 T 09-03-2017 L21SP3_RS04955 0109c3dac0801948d4ba529aae932f27 1126 SMART SM00409 735 819 9.0E-10 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS04955 0109c3dac0801948d4ba529aae932f27 1126 SMART SM00560 888 1021 3.4E-4 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS04955 0109c3dac0801948d4ba529aae932f27 1126 SUPERFAMILY SSF48726 726 808 3.96E-15 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS04955 0109c3dac0801948d4ba529aae932f27 1126 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 884 1019 1.2E-20 T 09-03-2017 L21SP3_RS04955 0109c3dac0801948d4ba529aae932f27 1126 Gene3D G3DSA:2.60.40.10 727 813 3.9E-15 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS10900 3eaea17d7b18cd85ec28e1bb9b31e921 177 Gene3D G3DSA:1.10.1740.10 6 96 1.3E-18 T 09-03-2017 L21SP3_RS10900 3eaea17d7b18cd85ec28e1bb9b31e921 177 Gene3D G3DSA:1.10.10.10 104 167 1.2E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS10900 3eaea17d7b18cd85ec28e1bb9b31e921 177 Pfam PF04542 Sigma-70 region 2 18 80 2.1E-11 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10900 3eaea17d7b18cd85ec28e1bb9b31e921 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 164 1.5E-21 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10900 3eaea17d7b18cd85ec28e1bb9b31e921 177 Pfam PF08281 Sigma-70, region 4 109 156 7.1E-7 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10900 3eaea17d7b18cd85ec28e1bb9b31e921 177 SUPERFAMILY SSF88659 107 167 3.55E-9 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10900 3eaea17d7b18cd85ec28e1bb9b31e921 177 TIGRFAM TIGR02989 Sig-70_gvs1: RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family 9 165 1.4E-41 T 09-03-2017 IPR014331 RNA polymerase sigma-70 ECF-like, Rhodopirellula baltica L21SP3_RS10900 3eaea17d7b18cd85ec28e1bb9b31e921 177 SUPERFAMILY SSF88946 7 87 2.62E-17 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS02820 a9d463ebf37a93a5dc80a73eae75ba64 893 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 729 883 3.0E-22 T 09-03-2017 L21SP3_RS02820 a9d463ebf37a93a5dc80a73eae75ba64 893 Gene3D G3DSA:1.50.10.10 119 267 1.5E-12 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS02820 a9d463ebf37a93a5dc80a73eae75ba64 893 SUPERFAMILY SSF49899 676 889 9.61E-32 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS02820 a9d463ebf37a93a5dc80a73eae75ba64 893 SUPERFAMILY SSF48208 94 404 1.36E-25 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS02820 a9d463ebf37a93a5dc80a73eae75ba64 893 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 45 578 5.6E-157 T 09-03-2017 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP3_RS02820 a9d463ebf37a93a5dc80a73eae75ba64 893 Gene3D G3DSA:2.60.120.200 667 888 1.8E-32 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS06085 625f9537c0a243184889566d1f55e95a 126 ProSitePatterns PS00054 Ribosomal protein S11 signature. 94 116 - T 09-03-2017 IPR018102 Ribosomal S11, conserved site L21SP3_RS06085 625f9537c0a243184889566d1f55e95a 126 SUPERFAMILY SSF53137 11 126 5.45E-47 T 09-03-2017 L21SP3_RS06085 625f9537c0a243184889566d1f55e95a 126 Gene3D G3DSA:3.30.420.80 4 126 3.9E-54 T 09-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06085 625f9537c0a243184889566d1f55e95a 126 PIRSF PIRSF002131 1 126 9.5E-53 T 09-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06085 625f9537c0a243184889566d1f55e95a 126 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 126 32.416 T 09-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06085 625f9537c0a243184889566d1f55e95a 126 Pfam PF00411 Ribosomal protein S11 16 125 7.6E-48 T 09-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06085 625f9537c0a243184889566d1f55e95a 126 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 7 123 5.5E-56 T 09-03-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04990 8909c8df7d9fc10b46cd3c52d774edd9 59 Gene3D G3DSA:1.10.10.60 17 47 1.6E-7 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS04990 8909c8df7d9fc10b46cd3c52d774edd9 59 Pfam PF01527 Transposase 2 58 1.8E-15 T 09-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 L21SP3_RS04990 8909c8df7d9fc10b46cd3c52d774edd9 59 SUPERFAMILY SSF46689 1 58 1.11E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS08325 0886a64ddc1e15ecb15f0904c7dfcd9d 127 Gene3D G3DSA:1.10.443.10 3 120 1.3E-17 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP3_RS08325 0886a64ddc1e15ecb15f0904c7dfcd9d 127 Pfam PF00589 Phage integrase family 3 121 4.9E-10 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP3_RS08325 0886a64ddc1e15ecb15f0904c7dfcd9d 127 SUPERFAMILY SSF56349 3 121 2.44E-18 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 L21SP3_RS05075 c4c353fbc8d173546d3c9ddc346c86c4 487 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 68 463 1.3E-109 T 09-03-2017 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 L21SP3_RS05075 c4c353fbc8d173546d3c9ddc346c86c4 487 SMART SM00729 194 420 1.2E-41 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP3_RS05075 c4c353fbc8d173546d3c9ddc346c86c4 487 Gene3D G3DSA:3.80.30.20 194 430 2.3E-62 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe L21SP3_RS05075 c4c353fbc8d173546d3c9ddc346c86c4 487 Pfam PF04055 Radical SAM superfamily 200 376 2.4E-20 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS05075 c4c353fbc8d173546d3c9ddc346c86c4 487 Pfam PF00919 Uncharacterized protein family UPF0004 66 149 9.1E-21 T 09-03-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 L21SP3_RS05075 c4c353fbc8d173546d3c9ddc346c86c4 487 SUPERFAMILY SSF102114 193 418 4.97E-46 T 09-03-2017 L21SP3_RS05075 c4c353fbc8d173546d3c9ddc346c86c4 487 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 65 451 5.3E-104 T 09-03-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 L21SP3_RS06855 8b35ea0ce28a8099f6cd40c3ae953b02 449 SUPERFAMILY SSF56935 203 441 9.16E-7 T 09-03-2017 L21SP3_RS06855 8b35ea0ce28a8099f6cd40c3ae953b02 449 Pfam PF13372 Alginate export 63 432 7.8E-20 T 09-03-2017 IPR025388 Alginate export domain L21SP3_RS07400 eae0cd71ee57fb1f5c6899095acaafd0 354 Gene3D G3DSA:3.30.1330.10 20 173 8.2E-54 T 09-03-2017 IPR016188 PurM-like, N-terminal domain L21SP3_RS07400 eae0cd71ee57fb1f5c6899095acaafd0 354 Pfam PF00586 AIR synthase related protein, N-terminal domain 64 168 1.5E-16 T 09-03-2017 IPR016188 PurM-like, N-terminal domain L21SP3_RS07400 eae0cd71ee57fb1f5c6899095acaafd0 354 SUPERFAMILY SSF55326 5 174 1.18E-45 T 09-03-2017 L21SP3_RS07400 eae0cd71ee57fb1f5c6899095acaafd0 354 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 5 346 1.6E-131 T 09-03-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 L21SP3_RS07400 eae0cd71ee57fb1f5c6899095acaafd0 354 Pfam PF02769 AIR synthase related protein, C-terminal domain 180 353 1.2E-34 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain L21SP3_RS07400 eae0cd71ee57fb1f5c6899095acaafd0 354 Gene3D G3DSA:3.90.650.10 176 352 6.9E-68 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain L21SP3_RS07400 eae0cd71ee57fb1f5c6899095acaafd0 354 SUPERFAMILY SSF56042 176 352 1.09E-56 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain L21SP3_RS07400 eae0cd71ee57fb1f5c6899095acaafd0 354 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 5 351 44.385 T 09-03-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 L21SP3_RS01250 d1422eb14f36141ee68736ad78767dab 187 SUPERFAMILY SSF53271 12 186 5.51E-32 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like L21SP3_RS01250 d1422eb14f36141ee68736ad78767dab 187 Gene3D G3DSA:3.40.50.2020 5 186 5.6E-38 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like L21SP3_RS01250 d1422eb14f36141ee68736ad78767dab 187 Pfam PF00156 Phosphoribosyl transferase domain 23 153 4.0E-17 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 L21SP3_RS02390 725e3d5e87c4378e9ef9053d4b9c2c78 466 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 131 349 1.8E-61 T 09-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS02390 725e3d5e87c4378e9ef9053d4b9c2c78 466 PIRSF PIRSF039114 1 464 4.1E-230 T 09-03-2017 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS02390 725e3d5e87c4378e9ef9053d4b9c2c78 466 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 2 458 58.153 T 09-03-2017 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS02390 725e3d5e87c4378e9ef9053d4b9c2c78 466 SUPERFAMILY SSF52540 78 354 3.13E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02390 725e3d5e87c4378e9ef9053d4b9c2c78 466 Gene3D G3DSA:1.10.1140.10 363 418 9.4E-6 T 09-03-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS02390 725e3d5e87c4378e9ef9053d4b9c2c78 466 Gene3D G3DSA:3.40.50.300 77 354 8.0E-90 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02390 725e3d5e87c4378e9ef9053d4b9c2c78 466 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 340 349 - T 09-03-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS02390 725e3d5e87c4378e9ef9053d4b9c2c78 466 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 8 74 1.6E-10 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS02390 725e3d5e87c4378e9ef9053d4b9c2c78 466 SUPERFAMILY SSF47917 362 420 3.14E-7 T 09-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 SUPERFAMILY SSF54849 137 203 2.27E-22 T 09-03-2017 L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 Gene3D G3DSA:1.10.560.10 369 517 1.2E-36 T 09-03-2017 IPR027413 GroEL-like equatorial domain L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 PRINTS PR00298 60kDa chaperonin signature 26 52 4.7E-68 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 PRINTS PR00298 60kDa chaperonin signature 397 418 4.7E-68 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 PRINTS PR00298 60kDa chaperonin signature 267 290 4.7E-68 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 PRINTS PR00298 60kDa chaperonin signature 349 374 4.7E-68 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 PRINTS PR00298 60kDa chaperonin signature 82 109 4.7E-68 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 2.1E-97 T 09-03-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 SUPERFAMILY SSF52029 184 375 2.84E-79 T 09-03-2017 IPR027409 GroEL-like apical domain L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 Gene3D G3DSA:3.50.7.10 196 368 3.1E-89 T 09-03-2017 IPR027409 GroEL-like apical domain L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 Hamap MF_00600 60 kDa chaperonin [groL]. 1 537 38.591 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 SUPERFAMILY SSF48592 405 521 4.28E-69 T 09-03-2017 L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 SUPERFAMILY SSF48592 6 133 4.28E-69 T 09-03-2017 L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 526 9.2E-238 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 Gene3D G3DSA:1.10.560.10 5 195 6.6E-41 T 09-03-2017 IPR027413 GroEL-like equatorial domain L21SP3_RS06900 7c276b2148113cf6d5de63beba972678 538 ProSitePatterns PS00296 Chaperonins cpn60 signature. 404 415 - T 09-03-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 L21SP3_RS06360 9c4010af6d001bceb3806c6d3c856819 310 Gene3D G3DSA:3.40.50.150 41 306 6.7E-54 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS06360 9c4010af6d001bceb3806c6d3c856819 310 SUPERFAMILY SSF53335 45 290 1.61E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS06360 9c4010af6d001bceb3806c6d3c856819 310 Pfam PF01555 DNA methylase 61 284 3.7E-37 T 09-03-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 L21SP3_RS06360 9c4010af6d001bceb3806c6d3c856819 310 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 60 74 1.8E-30 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS06360 9c4010af6d001bceb3806c6d3c856819 310 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 245 263 1.8E-30 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS06360 9c4010af6d001bceb3806c6d3c856819 310 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 96 116 1.8E-30 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS06360 9c4010af6d001bceb3806c6d3c856819 310 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 226 243 1.8E-30 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS06360 9c4010af6d001bceb3806c6d3c856819 310 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 268 288 1.8E-30 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS06360 9c4010af6d001bceb3806c6d3c856819 310 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 64 70 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 L21SP3_RS04950 084aef2e7d329bba2dbd89e3d1801294 827 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 112 556 1.4E-75 T 09-03-2017 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP3_RS04950 084aef2e7d329bba2dbd89e3d1801294 827 Gene3D G3DSA:2.60.120.260 723 812 2.5E-6 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS04950 084aef2e7d329bba2dbd89e3d1801294 827 SUPERFAMILY SSF48208 104 366 1.56E-13 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS02880 89bd6c681c551591ce108a175c986d54 2093 ProSitePatterns PS00018 EF-hand calcium-binding domain. 2068 2080 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS02880 89bd6c681c551591ce108a175c986d54 2093 Pfam PF07705 CARDB 507 621 9.2E-10 T 09-03-2017 IPR011635 CARDB domain L21SP3_RS02880 89bd6c681c551591ce108a175c986d54 2093 Pfam PF07705 CARDB 879 980 2.4E-10 T 09-03-2017 IPR011635 CARDB domain L21SP3_RS02880 89bd6c681c551591ce108a175c986d54 2093 Pfam PF07705 CARDB 1238 1346 1.1E-13 T 09-03-2017 IPR011635 CARDB domain L21SP3_RS02880 89bd6c681c551591ce108a175c986d54 2093 Pfam PF07705 CARDB 1358 1463 1.6E-12 T 09-03-2017 IPR011635 CARDB domain L21SP3_RS02880 89bd6c681c551591ce108a175c986d54 2093 Pfam PF07705 CARDB 639 741 4.0E-18 T 09-03-2017 IPR011635 CARDB domain L21SP3_RS02880 89bd6c681c551591ce108a175c986d54 2093 Pfam PF07705 CARDB 754 866 9.5E-12 T 09-03-2017 IPR011635 CARDB domain L21SP3_RS02880 89bd6c681c551591ce108a175c986d54 2093 Pfam PF07705 CARDB 1118 1225 5.5E-11 T 09-03-2017 IPR011635 CARDB domain L21SP3_RS06885 8b3680fffaae0ea7a4b8c4010a5aa196 108 Pfam PF09723 Zinc ribbon domain 1 41 3.8E-16 T 09-03-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain L21SP3_RS06885 8b3680fffaae0ea7a4b8c4010a5aa196 108 SMART SM00834 1 42 6.9E-15 T 09-03-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain L21SP3_RS06885 8b3680fffaae0ea7a4b8c4010a5aa196 108 Gene3D G3DSA:2.20.28.10 6 35 1.0E-4 T 09-03-2017 IPR004039 Rubredoxin-type fold L21SP3_RS06885 8b3680fffaae0ea7a4b8c4010a5aa196 108 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 53 2.3E-19 T 09-03-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain L21SP3_RS10390 840344bf90070c1c61af75ec766d35e0 311 SUPERFAMILY SSF55073 140 310 3.61E-34 T 09-03-2017 IPR029787 Nucleotide cyclase L21SP3_RS10390 840344bf90070c1c61af75ec766d35e0 311 SMART SM00267 124 311 6.8E-29 T 09-03-2017 IPR000160 GGDEF domain L21SP3_RS10390 840344bf90070c1c61af75ec766d35e0 311 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 132 308 2.2E-35 T 09-03-2017 IPR000160 GGDEF domain L21SP3_RS10390 840344bf90070c1c61af75ec766d35e0 311 Pfam PF00990 Diguanylate cyclase, GGDEF domain 135 306 1.8E-29 T 09-03-2017 IPR000160 GGDEF domain L21SP3_RS10390 840344bf90070c1c61af75ec766d35e0 311 Gene3D G3DSA:3.30.70.270 137 309 5.1E-35 T 09-03-2017 L21SP3_RS04935 f4c0668b106b0f18564855c2ba2fd108 335 PRINTS PR00990 Ribokinase signature 242 253 7.0E-6 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 L21SP3_RS04935 f4c0668b106b0f18564855c2ba2fd108 335 PRINTS PR00990 Ribokinase signature 204 219 7.0E-6 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 L21SP3_RS04935 f4c0668b106b0f18564855c2ba2fd108 335 PRINTS PR00990 Ribokinase signature 57 76 7.0E-6 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 L21SP3_RS04935 f4c0668b106b0f18564855c2ba2fd108 335 Gene3D G3DSA:3.40.1190.20 7 330 1.4E-70 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS04935 f4c0668b106b0f18564855c2ba2fd108 335 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 272 285 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 L21SP3_RS04935 f4c0668b106b0f18564855c2ba2fd108 335 SUPERFAMILY SSF53613 6 317 7.79E-72 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS04935 f4c0668b106b0f18564855c2ba2fd108 335 Pfam PF00294 pfkB family carbohydrate kinase 54 318 1.1E-46 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB L21SP3_RS04120 c797341ff9e8f8bf4f1d4cd90125644e 377 SUPERFAMILY SSF56112 11 347 3.06E-22 T 09-03-2017 IPR011009 Protein kinase-like domain L21SP3_RS04120 c797341ff9e8f8bf4f1d4cd90125644e 377 Pfam PF01636 Phosphotransferase enzyme family 29 267 3.5E-19 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase L21SP3_RS04120 c797341ff9e8f8bf4f1d4cd90125644e 377 Gene3D G3DSA:3.90.1200.10 198 336 2.7E-9 T 09-03-2017 L21SP3_RS04755 819579b11a5f1a78dd0f668b8611b4ad 390 TIGRFAM TIGR04181 NHT_00031: aminotransferase, LLPSF_NHT_00031 family 5 369 1.3E-139 T 09-03-2017 IPR026385 Aminotransferase, LLPSF_NHT_00031 family L21SP3_RS04755 819579b11a5f1a78dd0f668b8611b4ad 390 Gene3D G3DSA:3.40.640.10 5 264 8.5E-77 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS04755 819579b11a5f1a78dd0f668b8611b4ad 390 SUPERFAMILY SSF53383 7 384 1.29E-95 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS04755 819579b11a5f1a78dd0f668b8611b4ad 390 PIRSF PIRSF000390 1 389 4.5E-90 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP3_RS04755 819579b11a5f1a78dd0f668b8611b4ad 390 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 382 1.1E-87 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP3_RS04755 819579b11a5f1a78dd0f668b8611b4ad 390 Gene3D G3DSA:3.90.1150.10 266 384 4.3E-32 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SUPERFAMILY SSF48452 657 755 2.88E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 Pfam PF13432 Tetratricopeptide repeat 1108 1158 0.0086 T 09-03-2017 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 Gene3D G3DSA:1.25.40.10 1436 1558 6.7E-15 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 Gene3D G3DSA:1.25.40.10 723 949 3.7E-33 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 Gene3D G3DSA:1.25.40.10 955 1066 2.8E-6 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 Gene3D G3DSA:1.25.40.10 659 684 3.7E-33 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 Gene3D G3DSA:1.25.40.10 1090 1402 1.4E-28 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SUPERFAMILY SSF48452 1224 1335 6.83E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SUPERFAMILY SSF48452 40 128 1.39E-12 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SUPERFAMILY SSF48452 184 339 1.39E-12 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 Gene3D G3DSA:1.25.40.10 182 337 8.2E-17 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 Gene3D G3DSA:1.25.40.10 515 572 8.2E-17 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 Gene3D G3DSA:1.25.40.10 41 126 8.2E-17 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 Pfam PF07719 Tetratricopeptide repeat 725 752 3.5E-5 T 09-03-2017 IPR013105 Tetratricopeptide repeat 2 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SUPERFAMILY SSF48452 723 847 2.4E-28 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SUPERFAMILY SSF48452 190 215 2.4E-28 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SUPERFAMILY SSF48452 1094 1262 2.4E-28 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SUPERFAMILY SSF48452 1441 1560 3.03E-12 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SMART SM00028 719 752 6.1E-5 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SMART SM00028 178 211 250.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SMART SM00028 787 820 0.027 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SMART SM00028 1101 1134 120.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SMART SM00028 821 854 0.088 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SMART SM00028 1135 1168 2.8 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SMART SM00028 1236 1269 370.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SMART SM00028 1307 1340 410.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SMART SM00028 40 73 210.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SMART SM00028 1528 1561 0.76 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 SUPERFAMILY SSF48452 791 993 3.45E-19 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 Pfam PF13181 Tetratricopeptide repeat 822 854 0.004 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 Pfam PF13181 Tetratricopeptide repeat 1529 1558 0.0011 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00520 9f196e3f05884e960a94adb44cc54e8b 1581 Pfam PF13181 Tetratricopeptide repeat 792 818 0.013 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS07810 0f99b1e73a566d7521e237825abb18db 591 SUPERFAMILY SSF49303 202 292 8.63E-7 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS07810 0f99b1e73a566d7521e237825abb18db 591 SUPERFAMILY SSF49785 26 196 6.8E-40 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS07810 0f99b1e73a566d7521e237825abb18db 591 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 31 197 2.4E-15 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS07810 0f99b1e73a566d7521e237825abb18db 591 PRINTS PR00132 Glycosyl hydrolase family 2 signature 303 317 3.0E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS07810 0f99b1e73a566d7521e237825abb18db 591 PRINTS PR00132 Glycosyl hydrolase family 2 signature 335 353 3.0E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS07810 0f99b1e73a566d7521e237825abb18db 591 PRINTS PR00132 Glycosyl hydrolase family 2 signature 493 508 3.0E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS07810 0f99b1e73a566d7521e237825abb18db 591 PRINTS PR00132 Glycosyl hydrolase family 2 signature 401 416 3.0E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS07810 0f99b1e73a566d7521e237825abb18db 591 SUPERFAMILY SSF51445 294 588 1.28E-69 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS07810 0f99b1e73a566d7521e237825abb18db 591 Gene3D G3DSA:3.20.20.80 295 588 1.1E-66 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS07810 0f99b1e73a566d7521e237825abb18db 591 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 295 584 9.2E-33 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS07810 0f99b1e73a566d7521e237825abb18db 591 Gene3D G3DSA:2.60.120.260 26 189 5.1E-40 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS07810 0f99b1e73a566d7521e237825abb18db 591 Gene3D G3DSA:2.60.40.320 190 292 1.9E-9 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS08865 934e6b6f2fbe47431dae4b8c14c041be 399 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 47 387 4.4E-32 T 09-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 L21SP3_RS08865 934e6b6f2fbe47431dae4b8c14c041be 399 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 68 287 2.3E-12 T 09-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain L21SP3_RS08865 934e6b6f2fbe47431dae4b8c14c041be 399 Gene3D G3DSA:2.40.50.100 72 107 2.0E-8 T 09-03-2017 L21SP3_RS08865 934e6b6f2fbe47431dae4b8c14c041be 399 Gene3D G3DSA:2.40.50.100 186 218 2.0E-8 T 09-03-2017 L21SP3_RS08865 934e6b6f2fbe47431dae4b8c14c041be 399 SUPERFAMILY SSF111369 61 235 1.06E-17 T 09-03-2017 L21SP3_RS01840 c8080192e11faa575e04a0af25229920 249 SMART SM00028 154 187 160.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS01840 c8080192e11faa575e04a0af25229920 249 SMART SM00028 115 148 13.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS01840 c8080192e11faa575e04a0af25229920 249 SMART SM00028 192 225 61.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS01840 c8080192e11faa575e04a0af25229920 249 Gene3D G3DSA:1.25.40.10 172 224 5.3E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS01840 c8080192e11faa575e04a0af25229920 249 Gene3D G3DSA:1.25.40.10 10 61 2.1E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS01840 c8080192e11faa575e04a0af25229920 249 Gene3D G3DSA:1.25.40.10 93 171 2.1E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS01840 c8080192e11faa575e04a0af25229920 249 SUPERFAMILY SSF48452 11 61 2.71E-11 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS01840 c8080192e11faa575e04a0af25229920 249 SUPERFAMILY SSF48452 93 224 2.71E-11 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS03875 3ef988534564b13ec846224b55811dda 283 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 24 1.4E-6 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS03875 3ef988534564b13ec846224b55811dda 283 Pfam PF13633 Prokaryotic N-terminal methylation site 3 28 1.6E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS03875 3ef988534564b13ec846224b55811dda 283 SUPERFAMILY SSF54523 5 113 7.85E-17 T 09-03-2017 L21SP3_RS03875 3ef988534564b13ec846224b55811dda 283 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 242 254 0.0012 T 09-03-2017 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP3_RS03875 3ef988534564b13ec846224b55811dda 283 Gene3D G3DSA:3.30.700.10 5 59 4.2E-6 T 09-03-2017 L21SP3_RS00495 89c36d8be739055b08c5ba65547dea65 732 ProSitePatterns PS01276 Peptidase family U32 signature. 203 221 - T 09-03-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 L21SP3_RS00495 89c36d8be739055b08c5ba65547dea65 732 Pfam PF01136 Peptidase family U32 121 327 9.1E-59 T 09-03-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 L21SP3_RS00495 89c36d8be739055b08c5ba65547dea65 732 Gene3D G3DSA:3.20.20.70 86 146 2.5E-4 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 Pfam PF04542 Sigma-70 region 2 386 451 9.8E-19 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 PRINTS PR00046 Major sigma-70 factor signature 406 419 7.9E-28 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 PRINTS PR00046 Major sigma-70 factor signature 430 438 7.9E-28 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 PRINTS PR00046 Major sigma-70 factor signature 554 566 7.9E-28 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 PRINTS PR00046 Major sigma-70 factor signature 590 601 7.9E-28 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 PRINTS PR00046 Major sigma-70 factor signature 575 590 7.9E-28 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 SUPERFAMILY SSF88659 455 529 5.67E-20 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 SUPERFAMILY SSF88659 513 613 1.38E-26 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 59 615 31.049 T 09-03-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 Pfam PF03979 Sigma-70 factor, region 1.1 62 135 2.7E-15 T 09-03-2017 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 378 614 1.5E-108 T 09-03-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 Gene3D G3DSA:1.10.10.10 545 615 3.9E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 Gene3D G3DSA:1.10.10.10 455 505 2.3E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 Gene3D G3DSA:1.10.601.10 13 186 1.7E-6 T 09-03-2017 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 Gene3D G3DSA:1.10.601.10 187 451 2.7E-59 T 09-03-2017 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 Pfam PF04539 Sigma-70 region 3 461 537 1.2E-23 T 09-03-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 575 601 - T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 Pfam PF00140 Sigma-70 factor, region 1.2 165 193 9.8E-12 T 09-03-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 SUPERFAMILY SSF88946 331 452 1.11E-52 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 SUPERFAMILY SSF88946 164 221 1.11E-52 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 382 603 3.5E-37 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS09800 efe76bf1b72a168a1e3a9bbbb8b682c5 628 Pfam PF04545 Sigma-70, region 4 551 603 3.3E-16 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS06625 5c8d1c7bcffb0fe0bffa0fe0517e86de 177 Gene3D G3DSA:3.90.226.10 5 175 4.1E-70 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS06625 5c8d1c7bcffb0fe0bffa0fe0517e86de 177 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 95 108 - T 09-03-2017 IPR033135 ClpP, histidine active site L21SP3_RS06625 5c8d1c7bcffb0fe0bffa0fe0517e86de 177 Pfam PF00574 Clp protease 5 175 1.2E-69 T 09-03-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA L21SP3_RS06625 5c8d1c7bcffb0fe0bffa0fe0517e86de 177 SUPERFAMILY SSF52096 5 175 1.66E-61 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS06625 5c8d1c7bcffb0fe0bffa0fe0517e86de 177 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 176 32.138 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP3_RS06625 5c8d1c7bcffb0fe0bffa0fe0517e86de 177 PRINTS PR00127 Clp protease catalytic subunit P signature 2 17 1.6E-39 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP3_RS06625 5c8d1c7bcffb0fe0bffa0fe0517e86de 177 PRINTS PR00127 Clp protease catalytic subunit P signature 94 113 1.6E-39 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP3_RS06625 5c8d1c7bcffb0fe0bffa0fe0517e86de 177 PRINTS PR00127 Clp protease catalytic subunit P signature 73 90 1.6E-39 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP3_RS06625 5c8d1c7bcffb0fe0bffa0fe0517e86de 177 PRINTS PR00127 Clp protease catalytic subunit P signature 42 62 1.6E-39 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP3_RS06625 5c8d1c7bcffb0fe0bffa0fe0517e86de 177 PRINTS PR00127 Clp protease catalytic subunit P signature 151 170 1.6E-39 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP3_RS02545 f80e76640c9693a41bd03b498ff87230 315 Gene3D G3DSA:3.40.50.10490 177 266 9.1E-4 T 09-03-2017 L21SP3_RS03190 f19fd2b2eb22ade17b3ad3ace630f82a 356 SUPERFAMILY SSF51735 155 264 1.35E-11 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS03190 f19fd2b2eb22ade17b3ad3ace630f82a 356 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 168 263 1.3E-6 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 L21SP3_RS03190 f19fd2b2eb22ade17b3ad3ace630f82a 356 SMART SM00997 150 291 1.1E-5 T 09-03-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 L21SP3_RS03190 f19fd2b2eb22ade17b3ad3ace630f82a 356 SUPERFAMILY SSF52283 18 151 2.21E-10 T 09-03-2017 L21SP3_RS03190 f19fd2b2eb22ade17b3ad3ace630f82a 356 Gene3D G3DSA:3.40.50.720 187 238 1.2E-7 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS03190 f19fd2b2eb22ade17b3ad3ace630f82a 356 Gene3D G3DSA:3.40.50.1480 18 186 1.8E-10 T 09-03-2017 L21SP3_RS09450 a39715fb83d1d2f648de7f3dc829c9fa 440 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 09-03-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 L21SP3_RS09450 a39715fb83d1d2f648de7f3dc829c9fa 440 Pfam PF00742 Homoserine dehydrogenase 139 318 3.4E-56 T 09-03-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 L21SP3_RS09450 a39715fb83d1d2f648de7f3dc829c9fa 440 Gene3D G3DSA:3.30.360.10 151 302 1.2E-47 T 09-03-2017 L21SP3_RS09450 a39715fb83d1d2f648de7f3dc829c9fa 440 Gene3D G3DSA:3.40.50.720 2 150 1.6E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS09450 a39715fb83d1d2f648de7f3dc829c9fa 440 SUPERFAMILY SSF55347 139 305 1.05E-46 T 09-03-2017 L21SP3_RS09450 a39715fb83d1d2f648de7f3dc829c9fa 440 Pfam PF01842 ACT domain 355 418 4.6E-12 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 L21SP3_RS09450 a39715fb83d1d2f648de7f3dc829c9fa 440 Gene3D G3DSA:3.30.70.260 352 419 2.1E-10 T 09-03-2017 L21SP3_RS09450 a39715fb83d1d2f648de7f3dc829c9fa 440 SUPERFAMILY SSF51735 4 160 9.87E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS09450 a39715fb83d1d2f648de7f3dc829c9fa 440 SUPERFAMILY SSF55021 352 421 4.31E-11 T 09-03-2017 L21SP3_RS09450 a39715fb83d1d2f648de7f3dc829c9fa 440 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 12 131 8.4E-17 T 09-03-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 L21SP3_RS09450 a39715fb83d1d2f648de7f3dc829c9fa 440 PIRSF PIRSF000098 3 435 3.8E-145 T 09-03-2017 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 Pfam PF00391 PEP-utilising enzyme, mobile domain 153 226 6.4E-23 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 SUPERFAMILY SSF51621 253 552 2.88E-94 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 185 196 - T 09-03-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 450 468 - T 09-03-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 SUPERFAMILY SSF52009 126 245 1.83E-35 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 6 568 2.9E-180 T 09-03-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 253 543 7.1E-100 T 09-03-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 Gene3D G3DSA:3.50.30.10 133 255 2.8E-38 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 Gene3D G3DSA:3.20.20.60 256 570 8.2E-97 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 Gene3D G3DSA:1.10.274.10 26 132 8.4E-28 T 09-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 PIRSF PIRSF000732 1 575 2.8E-201 T 09-03-2017 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 SUPERFAMILY SSF47831 26 143 3.66E-24 T 09-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 Pfam PF05524 PEP-utilising enzyme, N-terminal 5 127 1.9E-24 T 09-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 294 313 7.1E-24 T 09-03-2017 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 450 465 7.1E-24 T 09-03-2017 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 467 482 7.1E-24 T 09-03-2017 L21SP3_RS06565 c403417003e9539e0598f41e20fc6eb9 580 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 503 515 7.1E-24 T 09-03-2017 L21SP3_RS02735 d23af10d73fb7d1850e769f687e33913 281 Gene3D G3DSA:3.40.50.720 2 181 5.1E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS02735 d23af10d73fb7d1850e769f687e33913 281 SUPERFAMILY SSF51735 7 172 1.58E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS02735 d23af10d73fb7d1850e769f687e33913 281 Pfam PF02153 Prephenate dehydrogenase 20 270 9.2E-54 T 09-03-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 L21SP3_RS02735 d23af10d73fb7d1850e769f687e33913 281 SUPERFAMILY SSF48179 177 279 9.64E-28 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP3_RS03110 48c79729a0b02d12dc0de324bfd4eb4b 441 Hamap MF_01981 ATP-dependent 6-phosphofructokinase [pfkA]. 6 439 52.505 T 09-03-2017 IPR012004 Pyrophosphate-dependent phosphofructokinase TP0108-type GO:0003872|GO:0005524|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 L21SP3_RS03110 48c79729a0b02d12dc0de324bfd4eb4b 441 PIRSF PIRSF000534 1 441 2.4E-184 T 09-03-2017 IPR012004 Pyrophosphate-dependent phosphofructokinase TP0108-type GO:0003872|GO:0005524|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 L21SP3_RS03110 48c79729a0b02d12dc0de324bfd4eb4b 441 Pfam PF00365 Phosphofructokinase 82 386 1.3E-62 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03110 48c79729a0b02d12dc0de324bfd4eb4b 441 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 171 187 4.5E-24 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03110 48c79729a0b02d12dc0de324bfd4eb4b 441 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 243 259 4.5E-24 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03110 48c79729a0b02d12dc0de324bfd4eb4b 441 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 204 221 4.5E-24 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03110 48c79729a0b02d12dc0de324bfd4eb4b 441 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 83 102 4.5E-24 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03110 48c79729a0b02d12dc0de324bfd4eb4b 441 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 222 240 4.5E-24 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03110 48c79729a0b02d12dc0de324bfd4eb4b 441 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 300 312 4.5E-24 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03110 48c79729a0b02d12dc0de324bfd4eb4b 441 SUPERFAMILY SSF53784 57 437 2.62E-116 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03110 48c79729a0b02d12dc0de324bfd4eb4b 441 Gene3D G3DSA:3.40.50.450 58 301 5.0E-74 T 09-03-2017 L21SP3_RS10835 d76be03805f10b6d9297d5427f484e79 550 Gene3D G3DSA:1.10.8.50 258 333 2.1E-13 T 09-03-2017 L21SP3_RS10835 d76be03805f10b6d9297d5427f484e79 550 SUPERFAMILY SSF55874 41 251 2.49E-24 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS10835 d76be03805f10b6d9297d5427f484e79 550 Pfam PF09239 Topoisomerase VI B subunit, transducer 335 505 8.2E-56 T 09-03-2017 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 L21SP3_RS10835 d76be03805f10b6d9297d5427f484e79 550 SUPERFAMILY SSF54211 333 508 5.23E-52 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS10835 d76be03805f10b6d9297d5427f484e79 550 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 35 527 6.4E-154 T 09-03-2017 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS10835 d76be03805f10b6d9297d5427f484e79 550 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 33 544 30.221 T 09-03-2017 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS10835 d76be03805f10b6d9297d5427f484e79 550 Gene3D G3DSA:3.30.230.10 334 544 1.2E-73 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP3_RS10835 d76be03805f10b6d9297d5427f484e79 550 PIRSF PIRSF006553 25 550 6.4E-196 T 09-03-2017 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS10835 d76be03805f10b6d9297d5427f484e79 550 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 59 171 1.2E-9 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS10835 d76be03805f10b6d9297d5427f484e79 550 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 360 522 3.0E-44 T 09-03-2017 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 L21SP3_RS10835 d76be03805f10b6d9297d5427f484e79 550 SMART SM00387 56 208 0.0012 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS10835 d76be03805f10b6d9297d5427f484e79 550 Gene3D G3DSA:3.30.565.10 32 235 6.3E-26 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS00460 f10905b91026cd1596f2870915772450 380 SUPERFAMILY SSF53756 6 378 2.02E-71 T 09-03-2017 L21SP3_RS00460 f10905b91026cd1596f2870915772450 380 Pfam PF00534 Glycosyl transferases group 1 199 354 1.3E-27 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS00460 f10905b91026cd1596f2870915772450 380 Gene3D G3DSA:3.40.50.2000 178 354 1.5E-24 T 09-03-2017 L21SP3_RS00460 f10905b91026cd1596f2870915772450 380 Pfam PF13439 Glycosyltransferase Family 4 18 190 4.5E-15 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 L21SP3_RS02030 16de30e3042c615fbf23f994e419b804 350 SUPERFAMILY SSF52540 56 153 3.35E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02030 16de30e3042c615fbf23f994e419b804 350 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 24 334 3.1E-76 T 09-03-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 L21SP3_RS02030 16de30e3042c615fbf23f994e419b804 350 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 1 349 26.563 T 09-03-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 L21SP3_RS02030 16de30e3042c615fbf23f994e419b804 350 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 33 314 2.2E-54 T 09-03-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 L21SP3_RS08790 a28e959a3683710aa96d038506fb64cd 476 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 170 185 - T 09-03-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 L21SP3_RS08790 a28e959a3683710aa96d038506fb64cd 476 Gene3D G3DSA:3.90.190.20 331 464 2.0E-33 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS08790 a28e959a3683710aa96d038506fb64cd 476 Pfam PF08245 Mur ligase middle domain 75 303 1.6E-14 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS08790 a28e959a3683710aa96d038506fb64cd 476 SUPERFAMILY SSF53623 43 328 8.85E-86 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS08790 a28e959a3683710aa96d038506fb64cd 476 TIGRFAM TIGR01499 folC: bifunctional protein FolC 53 460 3.6E-114 T 09-03-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 L21SP3_RS08790 a28e959a3683710aa96d038506fb64cd 476 PIRSF PIRSF001563 30 468 7.8E-135 T 09-03-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 L21SP3_RS08790 a28e959a3683710aa96d038506fb64cd 476 Pfam PF02875 Mur ligase family, glutamate ligase domain 330 404 1.4E-11 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS08790 a28e959a3683710aa96d038506fb64cd 476 Gene3D G3DSA:3.40.1190.10 21 330 5.0E-92 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS08790 a28e959a3683710aa96d038506fb64cd 476 SUPERFAMILY SSF53244 331 465 4.27E-27 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS01000 14ff7aa7cde73a4fc8ec57368c27d4d1 338 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 249 337 3.0E-34 T 09-03-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 L21SP3_RS01000 14ff7aa7cde73a4fc8ec57368c27d4d1 338 Gene3D G3DSA:3.40.47.10 13 172 5.9E-65 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01000 14ff7aa7cde73a4fc8ec57368c27d4d1 338 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 13 338 67.039 T 09-03-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 L21SP3_RS01000 14ff7aa7cde73a4fc8ec57368c27d4d1 338 Gene3D G3DSA:3.40.47.10 173 337 9.6E-49 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01000 14ff7aa7cde73a4fc8ec57368c27d4d1 338 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 118 197 4.3E-31 T 09-03-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 L21SP3_RS01000 14ff7aa7cde73a4fc8ec57368c27d4d1 338 SUPERFAMILY SSF53901 16 337 6.37E-69 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01000 14ff7aa7cde73a4fc8ec57368c27d4d1 338 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 14 338 7.0E-123 T 09-03-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 L21SP3_RS08965 9cb094833a3a54c21fc9db675a787a3a 992 Pfam PF13361 UvrD-like helicase C-terminal domain 326 721 4.7E-29 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 L21SP3_RS08965 9cb094833a3a54c21fc9db675a787a3a 992 Gene3D G3DSA:3.40.50.300 328 458 2.0E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08965 9cb094833a3a54c21fc9db675a787a3a 992 Gene3D G3DSA:3.40.50.300 624 767 2.0E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08965 9cb094833a3a54c21fc9db675a787a3a 992 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 318 2.1E-67 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 L21SP3_RS08965 9cb094833a3a54c21fc9db675a787a3a 992 SUPERFAMILY SSF52980 813 987 2.9E-14 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 L21SP3_RS08965 9cb094833a3a54c21fc9db675a787a3a 992 Gene3D G3DSA:3.90.320.10 805 981 1.0E-9 T 09-03-2017 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 L21SP3_RS08965 9cb094833a3a54c21fc9db675a787a3a 992 Pfam PF12705 PD-(D/E)XK nuclease superfamily 821 983 3.3E-12 T 09-03-2017 L21SP3_RS08965 9cb094833a3a54c21fc9db675a787a3a 992 Gene3D G3DSA:3.40.50.300 2 159 1.3E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08965 9cb094833a3a54c21fc9db675a787a3a 992 Gene3D G3DSA:3.40.50.300 224 321 1.3E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08965 9cb094833a3a54c21fc9db675a787a3a 992 Gene3D G3DSA:1.10.486.10 472 613 3.0E-16 T 09-03-2017 L21SP3_RS08965 9cb094833a3a54c21fc9db675a787a3a 992 SUPERFAMILY SSF52540 3 187 3.71E-107 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08965 9cb094833a3a54c21fc9db675a787a3a 992 SUPERFAMILY SSF52540 214 665 3.71E-107 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08965 9cb094833a3a54c21fc9db675a787a3a 992 SUPERFAMILY SSF52540 700 726 3.71E-107 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10500 17e4671054d80357f737ee86617be1b1 385 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 35 373 6.8E-43 T 09-03-2017 L21SP3_RS10500 17e4671054d80357f737ee86617be1b1 385 Gene3D G3DSA:1.50.10.10 2 383 6.8E-98 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS10500 17e4671054d80357f737ee86617be1b1 385 SUPERFAMILY SSF48208 8 383 1.16E-76 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS08620 a3e392a221c688f8588914c8af1cfce8 450 SMART SM00740 140 207 7.2E-14 T 09-03-2017 IPR005543 PASTA domain L21SP3_RS08620 a3e392a221c688f8588914c8af1cfce8 450 Gene3D G3DSA:3.90.1580.10 235 449 7.9E-42 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS08620 a3e392a221c688f8588914c8af1cfce8 450 SUPERFAMILY SSF56436 235 449 1.15E-42 T 09-03-2017 IPR016187 C-type lectin fold L21SP3_RS08620 a3e392a221c688f8588914c8af1cfce8 450 Pfam PF03781 Sulfatase-modifying factor enzyme 1 235 449 5.5E-33 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS08620 a3e392a221c688f8588914c8af1cfce8 450 ProSitePatterns PS00018 EF-hand calcium-binding domain. 117 129 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS08620 a3e392a221c688f8588914c8af1cfce8 450 Pfam PF03793 PASTA domain 146 206 7.1E-14 T 09-03-2017 IPR005543 PASTA domain L21SP3_RS08620 a3e392a221c688f8588914c8af1cfce8 450 Gene3D G3DSA:1.10.1330.10 117 139 7.4E-4 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS09835 7e6a3faa001b5318ab23b0355cba6c1d 204 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 7 64 2.7E-11 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP3_RS09835 7e6a3faa001b5318ab23b0355cba6c1d 204 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 3 199 28.335 T 09-03-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 L21SP3_RS09835 7e6a3faa001b5318ab23b0355cba6c1d 204 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 7 198 1.8E-53 T 09-03-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 L21SP3_RS09835 7e6a3faa001b5318ab23b0355cba6c1d 204 Pfam PF01467 Cytidylyltransferase-like 7 173 1.5E-29 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP3_RS09835 7e6a3faa001b5318ab23b0355cba6c1d 204 SUPERFAMILY SSF52374 2 198 3.94E-50 T 09-03-2017 L21SP3_RS09835 7e6a3faa001b5318ab23b0355cba6c1d 204 Gene3D G3DSA:3.40.50.620 3 201 4.3E-60 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS07725 58327e51c6fd6160e607f6d6e682d0df 242 SMART SM00382 26 236 1.2E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS07725 58327e51c6fd6160e607f6d6e682d0df 242 Pfam PF00005 ABC transporter 18 162 1.8E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS07725 58327e51c6fd6160e607f6d6e682d0df 242 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 212 233 3.0E-5 T 09-03-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal L21SP3_RS07725 58327e51c6fd6160e607f6d6e682d0df 242 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 2 237 3.2E-94 T 09-03-2017 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 L21SP3_RS07725 58327e51c6fd6160e607f6d6e682d0df 242 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS07725 58327e51c6fd6160e607f6d6e682d0df 242 SUPERFAMILY SSF52540 2 232 3.39E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07725 58327e51c6fd6160e607f6d6e682d0df 242 Gene3D G3DSA:3.40.50.300 2 229 5.6E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00690 6d69f2fd5c67444aa0662c10e2d3b872 221 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 29 3.7E-5 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS00690 6d69f2fd5c67444aa0662c10e2d3b872 221 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 27 9.9E-5 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS00690 6d69f2fd5c67444aa0662c10e2d3b872 221 SUPERFAMILY SSF54523 10 124 5.02E-13 T 09-03-2017 L21SP3_RS02065 6aeb589927d27ff982cf8db610e34c37 316 Pfam PF14572 Phosphoribosyl synthetase-associated domain 207 313 2.1E-24 T 09-03-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 L21SP3_RS02065 6aeb589927d27ff982cf8db610e34c37 316 SUPERFAMILY SSF53271 72 306 1.9E-56 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like L21SP3_RS02065 6aeb589927d27ff982cf8db610e34c37 316 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 7 315 44.473 T 09-03-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 L21SP3_RS02065 6aeb589927d27ff982cf8db610e34c37 316 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 8 123 3.2E-48 T 09-03-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 L21SP3_RS02065 6aeb589927d27ff982cf8db610e34c37 316 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 8 314 1.4E-118 T 09-03-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 L21SP3_RS02065 6aeb589927d27ff982cf8db610e34c37 316 SMART SM01400 7 123 1.1E-77 T 09-03-2017 L21SP3_RS02065 6aeb589927d27ff982cf8db610e34c37 316 Gene3D G3DSA:3.40.50.2020 162 282 4.0E-47 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like L21SP3_RS02065 6aeb589927d27ff982cf8db610e34c37 316 Gene3D G3DSA:3.40.50.2020 5 161 7.3E-72 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like L21SP3_RS02795 835432fd6635a02d0d26a3ebb71599c7 258 Pfam PF00731 AIR carboxylase 125 249 6.8E-14 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 L21SP3_RS02795 835432fd6635a02d0d26a3ebb71599c7 258 SUPERFAMILY SSF52255 124 252 2.09E-26 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 L21SP3_RS02795 835432fd6635a02d0d26a3ebb71599c7 258 Gene3D G3DSA:3.40.50.7700 124 251 1.5E-22 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 L21SP3_RS02795 835432fd6635a02d0d26a3ebb71599c7 258 SMART SM01001 123 255 1.2E-26 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 L21SP3_RS10480 1d405031817cce396155545d47c1969f 356 Gene3D G3DSA:3.40.50.2300 178 322 4.6E-34 T 09-03-2017 L21SP3_RS10480 1d405031817cce396155545d47c1969f 356 Gene3D G3DSA:3.40.50.2300 55 177 2.8E-36 T 09-03-2017 L21SP3_RS10480 1d405031817cce396155545d47c1969f 356 SUPERFAMILY SSF47413 5 63 4.13E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS10480 1d405031817cce396155545d47c1969f 356 Pfam PF13377 Periplasmic binding protein-like domain 175 345 1.8E-28 T 09-03-2017 L21SP3_RS10480 1d405031817cce396155545d47c1969f 356 Gene3D G3DSA:1.10.260.40 4 54 1.2E-19 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS10480 1d405031817cce396155545d47c1969f 356 SUPERFAMILY SSF53822 65 347 6.48E-55 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS10480 1d405031817cce396155545d47c1969f 356 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 1.9E-13 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 L21SP3_RS10480 1d405031817cce396155545d47c1969f 356 SMART SM00354 5 75 2.9E-22 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 L21SP3_RS07685 bb321a7c14e3ba946a38b296f16cd3ff 392 PIRSF PIRSF005243 1 390 1.1E-119 T 09-03-2017 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 L21SP3_RS07685 bb321a7c14e3ba946a38b296f16cd3ff 392 Gene3D G3DSA:3.40.50.360 246 385 6.5E-26 T 09-03-2017 IPR029039 Flavoprotein-like domain L21SP3_RS07685 bb321a7c14e3ba946a38b296f16cd3ff 392 SMART SM00849 32 220 7.5E-23 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS07685 bb321a7c14e3ba946a38b296f16cd3ff 392 SUPERFAMILY SSF56281 1 271 1.44E-45 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS07685 bb321a7c14e3ba946a38b296f16cd3ff 392 SUPERFAMILY SSF52218 244 386 3.53E-23 T 09-03-2017 IPR029039 Flavoprotein-like domain L21SP3_RS07685 bb321a7c14e3ba946a38b296f16cd3ff 392 Gene3D G3DSA:3.60.15.10 2 237 3.4E-77 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS07685 bb321a7c14e3ba946a38b296f16cd3ff 392 Pfam PF00753 Metallo-beta-lactamase superfamily 32 167 4.9E-7 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS08195 3683ccc99e7eb1b9f7f40ccb3cb55226 496 SUPERFAMILY SSF53649 39 480 1.02E-131 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS08195 3683ccc99e7eb1b9f7f40ccb3cb55226 496 ProSitePatterns PS00523 Sulfatases signature 1. 85 97 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS08195 3683ccc99e7eb1b9f7f40ccb3cb55226 496 Pfam PF00884 Sulfatase 39 364 3.4E-75 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS08195 3683ccc99e7eb1b9f7f40ccb3cb55226 496 Gene3D G3DSA:3.40.720.10 37 378 1.5E-114 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08195 3683ccc99e7eb1b9f7f40ccb3cb55226 496 Pfam PF14707 C-terminal region of aryl-sulfatase 389 486 2.2E-11 T 09-03-2017 L21SP3_RS08195 3683ccc99e7eb1b9f7f40ccb3cb55226 496 Gene3D G3DSA:3.30.1120.10 379 477 1.2E-18 T 09-03-2017 L21SP3_RS07875 dff366e16075df60f35ae7359fa2eedc 98 Gene3D G3DSA:3.30.70.900 1 97 2.5E-33 T 09-03-2017 L21SP3_RS07875 dff366e16075df60f35ae7359fa2eedc 98 SMART SM00886 2 98 1.0E-14 T 09-03-2017 IPR013097 Stress responsive alpha-beta barrel L21SP3_RS07875 dff366e16075df60f35ae7359fa2eedc 98 Pfam PF07876 Stress responsive A/B Barrel Domain 3 96 1.8E-15 T 09-03-2017 IPR013097 Stress responsive alpha-beta barrel L21SP3_RS07875 dff366e16075df60f35ae7359fa2eedc 98 SUPERFAMILY SSF54909 1 96 6.76E-21 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel L21SP3_RS10280 fb1f69d36a1ecfef7a9d6dd0c7d5a916 303 SUPERFAMILY SSF52440 5 96 2.11E-21 T 09-03-2017 IPR016185 Pre-ATP-grasp domain L21SP3_RS10280 fb1f69d36a1ecfef7a9d6dd0c7d5a916 303 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 5 301 28.511 T 09-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS10280 fb1f69d36a1ecfef7a9d6dd0c7d5a916 303 PIRSF PIRSF039102 45 303 1.8E-68 T 09-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS10280 fb1f69d36a1ecfef7a9d6dd0c7d5a916 303 SUPERFAMILY SSF56059 97 301 2.0E-38 T 09-03-2017 L21SP3_RS10280 fb1f69d36a1ecfef7a9d6dd0c7d5a916 303 Gene3D G3DSA:3.40.50.20 5 85 5.2E-21 T 09-03-2017 IPR016185 Pre-ATP-grasp domain L21SP3_RS10280 fb1f69d36a1ecfef7a9d6dd0c7d5a916 303 Gene3D G3DSA:3.30.470.20 86 104 1.1E-39 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP3_RS10280 fb1f69d36a1ecfef7a9d6dd0c7d5a916 303 Gene3D G3DSA:3.30.470.20 178 301 1.1E-39 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP3_RS10280 fb1f69d36a1ecfef7a9d6dd0c7d5a916 303 Pfam PF01820 D-ala D-ala ligase N-terminus 6 87 1.2E-16 T 09-03-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS10280 fb1f69d36a1ecfef7a9d6dd0c7d5a916 303 Pfam PF07478 D-ala D-ala ligase C-terminus 128 298 1.9E-42 T 09-03-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS10280 fb1f69d36a1ecfef7a9d6dd0c7d5a916 303 Gene3D G3DSA:3.30.1490.20 109 177 2.4E-8 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP3_RS10280 fb1f69d36a1ecfef7a9d6dd0c7d5a916 303 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 244 271 - T 09-03-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS06500 84feb6a915e4bd98795854ab4307847d 413 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 54 249 2.0E-18 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP3_RS06500 84feb6a915e4bd98795854ab4307847d 413 SMART SM00331 26 250 1.9E-4 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP3_RS06500 84feb6a915e4bd98795854ab4307847d 413 SUPERFAMILY SSF81606 39 250 3.01E-11 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP3_RS06500 84feb6a915e4bd98795854ab4307847d 413 Gene3D G3DSA:3.60.40.10 163 250 2.7E-6 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 L21SP3_RS06595 c37defede708e0642a42512c1e5e8299 714 SMART SM00409 359 452 4.8E-4 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS06595 c37defede708e0642a42512c1e5e8299 714 SUPERFAMILY SSF49899 449 665 2.44E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS06595 c37defede708e0642a42512c1e5e8299 714 Gene3D G3DSA:2.60.40.10 352 452 1.3E-14 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS06595 c37defede708e0642a42512c1e5e8299 714 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 517 661 4.1E-17 T 09-03-2017 L21SP3_RS06595 c37defede708e0642a42512c1e5e8299 714 Pfam PF07679 Immunoglobulin I-set domain 354 445 7.8E-9 T 09-03-2017 IPR013098 Immunoglobulin I-set L21SP3_RS06595 c37defede708e0642a42512c1e5e8299 714 Gene3D G3DSA:2.60.120.200 453 667 2.5E-28 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS06595 c37defede708e0642a42512c1e5e8299 714 SUPERFAMILY SSF48726 353 452 1.58E-12 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS09165 32fea00b4e6ae69836f8178099b5a162 136 SUPERFAMILY SSF160537 1 56 1.83E-25 T 09-03-2017 IPR007170 Stage V sporulation protein G GO:0030435 L21SP3_RS09165 32fea00b4e6ae69836f8178099b5a162 136 SUPERFAMILY SSF160537 93 122 1.83E-25 T 09-03-2017 IPR007170 Stage V sporulation protein G GO:0030435 L21SP3_RS09165 32fea00b4e6ae69836f8178099b5a162 136 Gene3D G3DSA:3.30.1120.40 1 55 9.8E-35 T 09-03-2017 IPR007170 Stage V sporulation protein G GO:0030435 L21SP3_RS09165 32fea00b4e6ae69836f8178099b5a162 136 Gene3D G3DSA:3.30.1120.40 92 120 9.8E-35 T 09-03-2017 IPR007170 Stage V sporulation protein G GO:0030435 L21SP3_RS09165 32fea00b4e6ae69836f8178099b5a162 136 Pfam PF04026 SpoVG 1 119 1.2E-33 T 09-03-2017 IPR007170 Stage V sporulation protein G GO:0030435 L21SP3_RS09165 32fea00b4e6ae69836f8178099b5a162 136 Pfam PF13240 zinc-ribbon domain 57 78 8.0E-7 T 09-03-2017 IPR026870 Zinc-ribbon domain L21SP3_RS03355 faa93d4ade6cf5d5dd99d7150374767c 93 Gene3D G3DSA:1.10.1270.10 2 90 1.5E-22 T 09-03-2017 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 L21SP3_RS03355 faa93d4ade6cf5d5dd99d7150374767c 93 SUPERFAMILY SSF48295 3 87 8.37E-20 T 09-03-2017 IPR010921 Trp repressor/replication initiator GO:0043565 L21SP3_RS03355 faa93d4ade6cf5d5dd99d7150374767c 93 ProDom PD012582 REPRESSOR TRANSCRIPTION TRP OPERON DNA-BINDING REGULATION HOMOLOG AROH FOR TRYPTOPHAN 10 85 4.0E-6 T 09-03-2017 IPR013335 Trp repressor, bacterial GO:0006355 L21SP3_RS03355 faa93d4ade6cf5d5dd99d7150374767c 93 Pfam PF01371 Trp repressor protein 3 85 1.0E-19 T 09-03-2017 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 L21SP3_RS07040 db049d82a9453b0b93369a18c15d0997 283 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 25 1.0E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS07040 db049d82a9453b0b93369a18c15d0997 283 Gene3D G3DSA:3.30.700.10 6 58 5.0E-6 T 09-03-2017 L21SP3_RS07040 db049d82a9453b0b93369a18c15d0997 283 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS07040 db049d82a9453b0b93369a18c15d0997 283 SUPERFAMILY SSF54523 6 96 6.83E-14 T 09-03-2017 L21SP3_RS07040 db049d82a9453b0b93369a18c15d0997 283 Pfam PF13633 Prokaryotic N-terminal methylation site 4 29 5.4E-9 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS06680 3e86a3d9c704d4b377ec52cc3a4cdf3d 329 PIRSF PIRSF002849 3 329 3.2E-137 T 09-03-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted L21SP3_RS06680 3e86a3d9c704d4b377ec52cc3a4cdf3d 329 SUPERFAMILY SSF52540 19 301 1.85E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06680 3e86a3d9c704d4b377ec52cc3a4cdf3d 329 Gene3D G3DSA:1.10.8.300 210 326 3.3E-38 T 09-03-2017 L21SP3_RS06680 3e86a3d9c704d4b377ec52cc3a4cdf3d 329 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 49 179 5.1E-66 T 09-03-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 L21SP3_RS06680 3e86a3d9c704d4b377ec52cc3a4cdf3d 329 Gene3D G3DSA:3.40.50.300 30 195 4.0E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11415 88bd55809b8892922879a435e31cc49e 457 PRINTS PR00394 RHS protein signature 297 316 5.9E-7 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11415 88bd55809b8892922879a435e31cc49e 457 PRINTS PR00394 RHS protein signature 274 294 5.9E-7 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11415 88bd55809b8892922879a435e31cc49e 457 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 246 329 1.7E-24 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 Gene3D G3DSA:1.10.10.10 3 136 4.6E-36 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 3 362 35.383 T 09-03-2017 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 Gene3D G3DSA:3.40.1360.10 139 359 4.3E-64 T 09-03-2017 L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 SUPERFAMILY SSF56726 68 361 2.22E-86 T 09-03-2017 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 218 238 8.6E-36 T 09-03-2017 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 104 121 8.6E-36 T 09-03-2017 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 163 181 8.6E-36 T 09-03-2017 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 333 356 8.6E-36 T 09-03-2017 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 35 55 8.6E-36 T 09-03-2017 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 Pfam PF04406 Type IIB DNA topoisomerase 68 131 1.9E-16 T 09-03-2017 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 188 205 2.7E-13 T 09-03-2017 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 212 233 2.7E-13 T 09-03-2017 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 110 127 2.7E-13 T 09-03-2017 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 L21SP3_RS03255 eff1f3586349a5cb1f754cb30824e231 364 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 92 103 2.7E-13 T 09-03-2017 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 L21SP3_RS07285 44bdee58235c0ca17fd137e7b1534f4b 486 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 6 215 1.7E-50 T 09-03-2017 IPR007357 Deoxyribodipyrimidine photolyase-related protein L21SP3_RS07285 44bdee58235c0ca17fd137e7b1534f4b 486 Gene3D G3DSA:1.25.40.80 214 298 1.5E-9 T 09-03-2017 L21SP3_RS07285 44bdee58235c0ca17fd137e7b1534f4b 486 SUPERFAMILY SSF48173 216 473 7.46E-51 T 09-03-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 L21SP3_RS07285 44bdee58235c0ca17fd137e7b1534f4b 486 Pfam PF03441 FAD binding domain of DNA photolyase 299 388 1.6E-5 T 09-03-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 L21SP3_RS07285 44bdee58235c0ca17fd137e7b1534f4b 486 Gene3D G3DSA:1.10.579.10 299 435 7.6E-12 T 09-03-2017 L21SP3_RS08970 e81fd2225a56b20f9a8093af097cb278 449 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 42 277 4.6E-43 T 09-03-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region L21SP3_RS08970 e81fd2225a56b20f9a8093af097cb278 449 Gene3D G3DSA:3.40.30.10 293 448 2.6E-63 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS08970 e81fd2225a56b20f9a8093af097cb278 449 Pfam PF00255 Glutathione peroxidase 290 396 7.0E-41 T 09-03-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 L21SP3_RS08970 e81fd2225a56b20f9a8093af097cb278 449 PRINTS PR01011 Glutathione peroxidase family signature 343 359 2.3E-17 T 09-03-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 L21SP3_RS08970 e81fd2225a56b20f9a8093af097cb278 449 PRINTS PR01011 Glutathione peroxidase family signature 409 418 2.3E-17 T 09-03-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 L21SP3_RS08970 e81fd2225a56b20f9a8093af097cb278 449 PRINTS PR01011 Glutathione peroxidase family signature 308 325 2.3E-17 T 09-03-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 L21SP3_RS08970 e81fd2225a56b20f9a8093af097cb278 449 Gene3D G3DSA:2.120.10.30 33 292 1.6E-55 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like L21SP3_RS08970 e81fd2225a56b20f9a8093af097cb278 449 ProSitePatterns PS00460 Glutathione peroxidases active site. 310 325 - T 09-03-2017 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 L21SP3_RS08970 e81fd2225a56b20f9a8093af097cb278 449 SUPERFAMILY SSF52833 289 447 1.51E-54 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS08970 e81fd2225a56b20f9a8093af097cb278 449 SUPERFAMILY SSF63829 8 281 5.23E-55 T 09-03-2017 L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 Pfam PF00158 Sigma-54 interaction domain 154 318 4.1E-66 T 09-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 Pfam PF00072 Response regulator receiver domain 8 117 1.8E-11 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 365 374 - T 09-03-2017 IPR025944 Sigma-54 interaction domain, conserved site L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 Gene3D G3DSA:1.10.10.60 404 462 1.2E-19 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 Gene3D G3DSA:3.40.50.300 151 324 1.4E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 SMART SM00448 6 118 1.4E-8 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 SUPERFAMILY SSF52172 5 196 8.97E-23 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 SUPERFAMILY SSF52540 154 395 5.9E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 Gene3D G3DSA:3.40.50.2300 4 119 3.7E-17 T 09-03-2017 L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 443 463 3.0E-10 T 09-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 426 443 3.0E-10 T 09-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 Gene3D G3DSA:1.10.8.60 325 399 4.2E-24 T 09-03-2017 L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 SUPERFAMILY SSF46689 365 462 2.03E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 SMART SM00382 172 315 8.4E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS07075 23fee5b58f68e112d7bc69c9eeccf277 463 Pfam PF02954 Bacterial regulatory protein, Fis family 419 460 1.6E-14 T 09-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 L21SP3_RS02725 5361a033d4c3294b510a8e6145ee0dc3 100 Pfam PF02416 mttA/Hcf106 family 4 56 1.1E-13 T 09-03-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 L21SP3_RS02725 5361a033d4c3294b510a8e6145ee0dc3 100 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 87 16.201 T 09-03-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 L21SP3_RS02725 5361a033d4c3294b510a8e6145ee0dc3 100 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 45 3.5E-16 T 09-03-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 368 3.3E-152 T 09-03-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 Gene3D G3DSA:3.50.30.20 2 145 4.1E-63 T 09-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 PRINTS PR00096 Glutamine amidotransferase superfamily signature 257 268 2.6E-11 T 09-03-2017 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 PRINTS PR00096 Glutamine amidotransferase superfamily signature 230 239 2.6E-11 T 09-03-2017 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 PRINTS PR00096 Glutamine amidotransferase superfamily signature 342 355 2.6E-11 T 09-03-2017 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 SMART SM01097 1 131 1.1E-91 T 09-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 227 241 3.6E-38 T 09-03-2017 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 188 202 3.6E-38 T 09-03-2017 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 299 310 3.6E-38 T 09-03-2017 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 257 273 3.6E-38 T 09-03-2017 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 274 291 3.6E-38 T 09-03-2017 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 2 130 6.7E-56 T 09-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 Gene3D G3DSA:3.40.50.880 152 371 1.0E-72 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 SUPERFAMILY SSF52021 2 147 7.45E-60 T 09-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 371 49.886 T 09-03-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 Pfam PF00117 Glutamine amidotransferase class-I 191 365 6.0E-43 T 09-03-2017 IPR017926 Glutamine amidotransferase L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 PRINTS PR00097 Anthranilate synthase component II signature 230 239 1.2E-5 T 09-03-2017 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 PRINTS PR00097 Anthranilate synthase component II signature 257 268 1.2E-5 T 09-03-2017 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 PRINTS PR00097 Anthranilate synthase component II signature 342 355 1.2E-5 T 09-03-2017 L21SP3_RS00450 b8f85a1c4744faa8a4757ad6744c1166 372 SUPERFAMILY SSF52317 179 371 6.17E-57 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS06330 8bde1b83a66c52d101d50253a1cf17f0 95 SUPERFAMILY SSF47729 4 93 4.42E-26 T 09-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 L21SP3_RS06330 8bde1b83a66c52d101d50253a1cf17f0 95 PRINTS PR01727 Prokaryotic integration host factor signature 61 74 5.8E-9 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP3_RS06330 8bde1b83a66c52d101d50253a1cf17f0 95 PRINTS PR01727 Prokaryotic integration host factor signature 77 91 5.8E-9 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP3_RS06330 8bde1b83a66c52d101d50253a1cf17f0 95 PRINTS PR01727 Prokaryotic integration host factor signature 43 58 5.8E-9 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP3_RS06330 8bde1b83a66c52d101d50253a1cf17f0 95 Gene3D G3DSA:4.10.520.10 3 93 4.1E-28 T 09-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 L21SP3_RS06330 8bde1b83a66c52d101d50253a1cf17f0 95 SMART SM00411 4 93 4.2E-29 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP3_RS06330 8bde1b83a66c52d101d50253a1cf17f0 95 Pfam PF00216 Bacterial DNA-binding protein 4 92 1.5E-26 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 L21SP3_RS07480 38d419cbbed18d451bf2631003f2b4f3 315 Gene3D G3DSA:3.20.20.70 4 296 9.5E-78 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS07480 38d419cbbed18d451bf2631003f2b4f3 315 SUPERFAMILY SSF51569 6 296 7.43E-73 T 09-03-2017 L21SP3_RS07480 38d419cbbed18d451bf2631003f2b4f3 315 Pfam PF00701 Dihydrodipicolinate synthetase family 8 296 1.7E-58 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS07480 38d419cbbed18d451bf2631003f2b4f3 315 PIRSF PIRSF001365 4 305 6.1E-66 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS07480 38d419cbbed18d451bf2631003f2b4f3 315 PRINTS PR00146 Dihydrodipicolinate synthase signature 42 63 1.8E-13 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS07480 38d419cbbed18d451bf2631003f2b4f3 315 PRINTS PR00146 Dihydrodipicolinate synthase signature 110 126 1.8E-13 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS07480 38d419cbbed18d451bf2631003f2b4f3 315 PRINTS PR00146 Dihydrodipicolinate synthase signature 78 96 1.8E-13 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS07480 38d419cbbed18d451bf2631003f2b4f3 315 PRINTS PR00146 Dihydrodipicolinate synthase signature 135 152 1.8E-13 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS07480 38d419cbbed18d451bf2631003f2b4f3 315 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 140 170 - T 09-03-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS07480 38d419cbbed18d451bf2631003f2b4f3 315 SMART SM01130 8 298 1.0E-75 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS11150 4568b2ae28bc91f50682966eae02abdb 261 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 4 252 2.4E-76 T 09-03-2017 IPR005235 Metallophosphoesterase, YmdB-like L21SP3_RS11150 4568b2ae28bc91f50682966eae02abdb 261 Gene3D G3DSA:3.60.21.30 3 258 1.2E-98 T 09-03-2017 L21SP3_RS11150 4568b2ae28bc91f50682966eae02abdb 261 PIRSF PIRSF004789 2 261 5.2E-88 T 09-03-2017 IPR005235 Metallophosphoesterase, YmdB-like L21SP3_RS11150 4568b2ae28bc91f50682966eae02abdb 261 Pfam PF13277 YmdB-like protein 6 257 3.7E-96 T 09-03-2017 IPR005235 Metallophosphoesterase, YmdB-like L21SP3_RS11150 4568b2ae28bc91f50682966eae02abdb 261 SUPERFAMILY SSF56300 3 257 9.28E-73 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS09955 55bbf2fc04bf5789c05345987a4f3105 596 SUPERFAMILY SSF56645 51 270 1.57E-46 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 L21SP3_RS09955 55bbf2fc04bf5789c05345987a4f3105 596 Gene3D G3DSA:1.20.120.470 452 534 6.4E-15 T 09-03-2017 IPR020964 Acyl-CoA dehydrogenase, C-terminal L21SP3_RS09955 55bbf2fc04bf5789c05345987a4f3105 596 SUPERFAMILY SSF158494 447 531 2.22E-14 T 09-03-2017 IPR020964 Acyl-CoA dehydrogenase, C-terminal L21SP3_RS09955 55bbf2fc04bf5789c05345987a4f3105 596 Gene3D G3DSA:2.40.110.10 173 263 1.8E-22 T 09-03-2017 L21SP3_RS09955 55bbf2fc04bf5789c05345987a4f3105 596 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 174 268 1.2E-19 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 L21SP3_RS09955 55bbf2fc04bf5789c05345987a4f3105 596 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 53 169 2.2E-13 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 L21SP3_RS09955 55bbf2fc04bf5789c05345987a4f3105 596 SUPERFAMILY SSF47203 389 457 3.7E-40 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 L21SP3_RS09955 55bbf2fc04bf5789c05345987a4f3105 596 SUPERFAMILY SSF47203 283 357 3.7E-40 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 L21SP3_RS09955 55bbf2fc04bf5789c05345987a4f3105 596 Pfam PF12186 Acyl-CoA dehydrogenase C terminal 457 532 4.2E-10 T 09-03-2017 IPR020964 Acyl-CoA dehydrogenase, C-terminal L21SP3_RS09955 55bbf2fc04bf5789c05345987a4f3105 596 Gene3D G3DSA:1.20.140.10 264 451 1.1E-48 T 09-03-2017 L21SP3_RS09955 55bbf2fc04bf5789c05345987a4f3105 596 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 448 1.1E-26 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 L21SP3_RS09955 55bbf2fc04bf5789c05345987a4f3105 596 Gene3D G3DSA:1.10.540.10 52 171 1.8E-19 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 L21SP3_RS09710 90e0e92891a19e53fedb232180b507f8 453 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 337 444 1.9E-7 T 09-03-2017 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain L21SP3_RS09710 90e0e92891a19e53fedb232180b507f8 453 Pfam PF13440 Polysaccharide biosynthesis protein 41 336 8.8E-68 T 09-03-2017 L21SP3_RS09690 fe7bb1e5bfa1c4eb85228718ec79a87b 545 Pfam PF02540 NAD synthase 267 515 1.0E-71 T 09-03-2017 IPR022310 NAD/GMP synthase L21SP3_RS09690 fe7bb1e5bfa1c4eb85228718ec79a87b 545 SUPERFAMILY SSF56317 1 241 1.15E-63 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP3_RS09690 fe7bb1e5bfa1c4eb85228718ec79a87b 545 Pfam PF00795 Carbon-nitrogen hydrolase 2 243 7.7E-37 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP3_RS09690 fe7bb1e5bfa1c4eb85228718ec79a87b 545 SUPERFAMILY SSF52402 260 524 6.17E-73 T 09-03-2017 L21SP3_RS09690 fe7bb1e5bfa1c4eb85228718ec79a87b 545 Gene3D G3DSA:3.60.110.10 1 241 2.0E-61 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP3_RS09690 fe7bb1e5bfa1c4eb85228718ec79a87b 545 TIGRFAM TIGR00552 nadE: NAD+ synthetase 275 520 2.1E-59 T 09-03-2017 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 L21SP3_RS09690 fe7bb1e5bfa1c4eb85228718ec79a87b 545 PIRSF PIRSF006630 1 543 4.7E-191 T 09-03-2017 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 L21SP3_RS09690 fe7bb1e5bfa1c4eb85228718ec79a87b 545 Gene3D G3DSA:3.40.50.620 254 523 4.0E-75 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS09690 fe7bb1e5bfa1c4eb85228718ec79a87b 545 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 33 48 - T 09-03-2017 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 L21SP3_RS09405 35dd91a3ecad649ce44cc6e1772722aa 271 Pfam PF02535 ZIP Zinc transporter 117 264 1.7E-26 T 09-03-2017 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 L21SP3_RS09405 35dd91a3ecad649ce44cc6e1772722aa 271 Hamap MF_00548 Zinc transporter ZupT [zupT]. 8 271 34.176 T 09-03-2017 IPR023498 Zinc transporter ZupT L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 SUPERFAMILY SSF47473 544 600 1.24E-6 T 09-03-2017 IPR011992 EF-hand domain pair L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 SMART SM00054 489 517 6.5 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 SMART SM00054 571 601 2.6 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 SMART SM00054 51 79 4.3 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 SMART SM00054 441 471 160.0 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 Gene3D G3DSA:1.10.238.10 431 476 3.7E-17 T 09-03-2017 IPR011992 EF-hand domain pair L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 Gene3D G3DSA:1.10.238.10 477 599 1.2E-14 T 09-03-2017 IPR011992 EF-hand domain pair L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 Gene3D G3DSA:1.10.238.10 24 81 3.7E-17 T 09-03-2017 IPR011992 EF-hand domain pair L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 SUPERFAMILY SSF47473 25 81 4.43E-19 T 09-03-2017 IPR011992 EF-hand domain pair L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 SUPERFAMILY SSF47473 464 521 4.43E-19 T 09-03-2017 IPR011992 EF-hand domain pair L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 Pfam PF13202 EF hand 27 49 1.1E-4 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 Pfam PF13202 EF hand 493 513 0.0014 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 Pfam PF13202 EF hand 466 487 1.1E-4 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 Pfam PF13202 EF hand 577 594 0.0058 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 Pfam PF13202 EF hand 445 461 0.016 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 ProSitePatterns PS00018 EF-hand calcium-binding domain. 498 510 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 Gene3D G3DSA:3.40.50.1820 89 386 7.6E-45 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 Gene3D G3DSA:3.40.50.1820 8 22 7.6E-45 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 Pfam PF10503 Esterase PHB depolymerase 111 258 2.5E-10 T 09-03-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 SUPERFAMILY SSF53474 99 274 3.85E-30 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 SUPERFAMILY SSF53474 324 381 3.85E-30 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 ProSitePatterns PS00018 EF-hand calcium-binding domain. 60 72 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 ProSitePatterns PS00018 EF-hand calcium-binding domain. 560 572 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 ProSitePatterns PS00018 EF-hand calcium-binding domain. 34 46 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 ProSitePatterns PS00018 EF-hand calcium-binding domain. 582 594 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS08295 2aa955f297914d0011ab1b7631373b80 1055 ProSitePatterns PS00018 EF-hand calcium-binding domain. 472 484 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS09960 fb4de5ddeedc447c73b1d1db819a86c4 342 Gene3D G3DSA:3.40.50.620 9 210 1.0E-70 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS09960 fb4de5ddeedc447c73b1d1db819a86c4 342 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 218 301 3.6E-30 T 09-03-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 L21SP3_RS09960 fb4de5ddeedc447c73b1d1db819a86c4 342 SUPERFAMILY SSF52467 218 337 3.27E-43 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain L21SP3_RS09960 fb4de5ddeedc447c73b1d1db819a86c4 342 Pfam PF01012 Electron transfer flavoprotein domain 10 198 6.4E-44 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 L21SP3_RS09960 fb4de5ddeedc447c73b1d1db819a86c4 342 SMART SM00893 10 208 1.9E-43 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 L21SP3_RS09960 fb4de5ddeedc447c73b1d1db819a86c4 342 Gene3D G3DSA:3.40.50.1220 214 339 1.4E-50 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain L21SP3_RS09960 fb4de5ddeedc447c73b1d1db819a86c4 342 PIRSF PIRSF000089 7 342 1.5E-108 T 09-03-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 L21SP3_RS09960 fb4de5ddeedc447c73b1d1db819a86c4 342 SUPERFAMILY SSF52402 10 211 2.79E-54 T 09-03-2017 L21SP3_RS02885 8619ea9119288153732bafc185fae159 343 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 5 342 8.0E-138 T 09-03-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 L21SP3_RS02885 8619ea9119288153732bafc185fae159 343 Gene3D G3DSA:3.20.20.70 9 342 2.4E-133 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS02885 8619ea9119288153732bafc185fae159 343 PIRSF PIRSF001361 1 343 1.4E-144 T 09-03-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 L21SP3_RS02885 8619ea9119288153732bafc185fae159 343 SUPERFAMILY SSF51569 6 342 2.38E-120 T 09-03-2017 L21SP3_RS02885 8619ea9119288153732bafc185fae159 343 Pfam PF00793 DAHP synthetase I family 38 336 4.8E-87 T 09-03-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 L21SP3_RS07055 a0c15827541c55c02849e0de9ac4ccdd 781 Pfam PF02449 Beta-galactosidase 252 519 2.3E-9 T 09-03-2017 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS07055 a0c15827541c55c02849e0de9ac4ccdd 781 Gene3D G3DSA:3.20.20.80 213 523 1.1E-31 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS07055 a0c15827541c55c02849e0de9ac4ccdd 781 SUPERFAMILY SSF51445 433 536 1.61E-16 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS07055 a0c15827541c55c02849e0de9ac4ccdd 781 SUPERFAMILY SSF51445 209 403 1.61E-16 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS00275 2bd09f21898ad7c2e87aa7c5cc427d6e 544 Gene3D G3DSA:1.25.10.10 292 397 9.7E-11 T 09-03-2017 IPR011989 Armadillo-like helical L21SP3_RS00275 2bd09f21898ad7c2e87aa7c5cc427d6e 544 SUPERFAMILY SSF48371 295 397 1.84E-12 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 L21SP3_RS00275 2bd09f21898ad7c2e87aa7c5cc427d6e 544 Pfam PF13646 HEAT repeats 293 352 8.2E-7 T 09-03-2017 L21SP3_RS00275 2bd09f21898ad7c2e87aa7c5cc427d6e 544 PRINTS PR01010 Flagellar P-ring protein signature 56 71 1.2E-7 T 09-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 L21SP3_RS00275 2bd09f21898ad7c2e87aa7c5cc427d6e 544 PRINTS PR01010 Flagellar P-ring protein signature 202 220 1.2E-7 T 09-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 L21SP3_RS00275 2bd09f21898ad7c2e87aa7c5cc427d6e 544 PRINTS PR01010 Flagellar P-ring protein signature 104 123 1.2E-7 T 09-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 L21SP3_RS00275 2bd09f21898ad7c2e87aa7c5cc427d6e 544 Pfam PF02119 Flagellar P-ring protein 48 262 5.4E-19 T 09-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 L21SP3_RS00535 a2b0af9be1d67c0f5b35e782b46d5a63 184 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 71 79 1.9E-11 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 L21SP3_RS00535 a2b0af9be1d67c0f5b35e782b46d5a63 184 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 153 169 1.9E-11 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 L21SP3_RS00535 a2b0af9be1d67c0f5b35e782b46d5a63 184 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 114 129 1.9E-11 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 L21SP3_RS00535 a2b0af9be1d67c0f5b35e782b46d5a63 184 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 22 178 13.266 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 L21SP3_RS00535 a2b0af9be1d67c0f5b35e782b46d5a63 184 Pfam PF01252 Signal peptidase (SPase) II 31 170 3.5E-24 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 L21SP3_RS00535 a2b0af9be1d67c0f5b35e782b46d5a63 184 TIGRFAM TIGR00077 lspA: signal peptidase II 21 181 2.2E-23 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 L21SP3_RS03335 5b02a63b8cd75018da1b9e7c5066f347 197 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 118 128 - T 09-03-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 L21SP3_RS03335 5b02a63b8cd75018da1b9e7c5066f347 197 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 14 191 2.3E-70 T 09-03-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 L21SP3_RS03335 5b02a63b8cd75018da1b9e7c5066f347 197 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 10 191 40.483 T 09-03-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 L21SP3_RS03335 5b02a63b8cd75018da1b9e7c5066f347 197 Gene3D G3DSA:1.10.286.10 9 59 1.3E-24 T 09-03-2017 L21SP3_RS03335 5b02a63b8cd75018da1b9e7c5066f347 197 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 70 86 - T 09-03-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 L21SP3_RS03335 5b02a63b8cd75018da1b9e7c5066f347 197 Gene3D G3DSA:3.30.1130.10 63 191 5.1E-56 T 09-03-2017 L21SP3_RS03335 5b02a63b8cd75018da1b9e7c5066f347 197 Pfam PF01227 GTP cyclohydrolase I 14 190 1.3E-76 T 09-03-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 L21SP3_RS03335 5b02a63b8cd75018da1b9e7c5066f347 197 SUPERFAMILY SSF55620 4 191 8.89E-75 T 09-03-2017 L21SP3_RS03470 ffc28e94b5333908c6790b084d5101a0 328 Pfam PF05235 CHAD domain 17 250 1.5E-38 T 09-03-2017 IPR007899 CHAD domain L21SP3_RS03470 ffc28e94b5333908c6790b084d5101a0 328 SMART SM00880 16 286 1.9E-20 T 09-03-2017 IPR007899 CHAD domain L21SP3_RS11020 27ff9a3f9745663c9cbaca4e0b3630e8 233 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 125 232 2.0E-21 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11020 27ff9a3f9745663c9cbaca4e0b3630e8 233 SMART SM00388 15 83 2.1E-4 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11020 27ff9a3f9745663c9cbaca4e0b3630e8 233 SUPERFAMILY SSF55874 74 231 4.19E-32 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11020 27ff9a3f9745663c9cbaca4e0b3630e8 233 PRINTS PR00344 Bacterial sensor protein C-terminal signature 219 232 2.1E-11 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11020 27ff9a3f9745663c9cbaca4e0b3630e8 233 PRINTS PR00344 Bacterial sensor protein C-terminal signature 162 176 2.1E-11 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11020 27ff9a3f9745663c9cbaca4e0b3630e8 233 PRINTS PR00344 Bacterial sensor protein C-terminal signature 195 213 2.1E-11 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11020 27ff9a3f9745663c9cbaca4e0b3630e8 233 Gene3D G3DSA:1.10.287.130 12 79 1.2E-9 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11020 27ff9a3f9745663c9cbaca4e0b3630e8 233 SUPERFAMILY SSF47384 11 82 1.39E-12 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11020 27ff9a3f9745663c9cbaca4e0b3630e8 233 Gene3D G3DSA:3.30.565.10 86 231 1.1E-33 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11020 27ff9a3f9745663c9cbaca4e0b3630e8 233 Pfam PF00512 His Kinase A (phospho-acceptor) domain 16 80 5.0E-7 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11020 27ff9a3f9745663c9cbaca4e0b3630e8 233 SMART SM00387 124 233 2.3E-18 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS02595 cfc3ed02a9aed9e51d36b9c255432550 407 SUPERFAMILY SSF51713 35 398 1.27E-147 T 09-03-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 L21SP3_RS02595 cfc3ed02a9aed9e51d36b9c255432550 407 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 34 392 53.13 T 09-03-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 L21SP3_RS02595 cfc3ed02a9aed9e51d36b9c255432550 407 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 41 400 1.1E-149 T 09-03-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 L21SP3_RS02595 cfc3ed02a9aed9e51d36b9c255432550 407 Gene3D G3DSA:3.20.20.105 35 399 9.9E-156 T 09-03-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 L21SP3_RS02595 cfc3ed02a9aed9e51d36b9c255432550 407 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 36 400 2.4E-144 T 09-03-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 L21SP3_RS02595 cfc3ed02a9aed9e51d36b9c255432550 407 Pfam PF01702 Queuine tRNA-ribosyltransferase 162 392 2.4E-83 T 09-03-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 L21SP3_RS11325 8772c5857622f21a016b564d0e300bcc 260 Gene3D G3DSA:1.10.1330.10 185 248 4.9E-5 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS08465 2754a8cc1b58d0794474ea5e6e595550 848 SMART SM00974 24 109 5.7E-12 T 09-03-2017 IPR018306 Bacteriophage T5, Orf172 DNA-binding L21SP3_RS08465 2754a8cc1b58d0794474ea5e6e595550 848 Pfam PF10544 T5orf172 domain 16 106 5.0E-7 T 09-03-2017 IPR018306 Bacteriophage T5, Orf172 DNA-binding L21SP3_RS08465 2754a8cc1b58d0794474ea5e6e595550 848 SUPERFAMILY SSF52540 306 319 2.17E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08465 2754a8cc1b58d0794474ea5e6e595550 848 SUPERFAMILY SSF52540 119 269 2.17E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08465 2754a8cc1b58d0794474ea5e6e595550 848 Gene3D G3DSA:3.40.50.300 120 322 1.1E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08465 2754a8cc1b58d0794474ea5e6e595550 848 Pfam PF04851 Type III restriction enzyme, res subunit 123 281 4.3E-7 T 09-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 L21SP3_RS08995 76f286208c0e4accb3d9e7ba4faeeed9 398 Gene3D G3DSA:3.40.50.150 257 375 1.1E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08995 76f286208c0e4accb3d9e7ba4faeeed9 398 Gene3D G3DSA:3.40.50.150 152 219 1.1E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08995 76f286208c0e4accb3d9e7ba4faeeed9 398 SMART SM00981 61 159 3.7E-4 T 09-03-2017 IPR004114 THUMP domain GO:0003723 L21SP3_RS08995 76f286208c0e4accb3d9e7ba4faeeed9 398 Pfam PF01170 Putative RNA methylase family UPF0020 167 373 2.5E-40 T 09-03-2017 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP3_RS08995 76f286208c0e4accb3d9e7ba4faeeed9 398 SUPERFAMILY SSF53335 149 222 3.11E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08995 76f286208c0e4accb3d9e7ba4faeeed9 398 SUPERFAMILY SSF53335 260 376 3.11E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS05150 6ad53d209b501758a2890cc6eea093af 169 SMART SM00506 4 133 8.8E-47 T 09-03-2017 IPR002589 Macro domain L21SP3_RS05150 6ad53d209b501758a2890cc6eea093af 169 Pfam PF01661 Macro domain 21 133 5.3E-43 T 09-03-2017 IPR002589 Macro domain L21SP3_RS05150 6ad53d209b501758a2890cc6eea093af 169 SUPERFAMILY SSF52949 4 166 2.35E-62 T 09-03-2017 L21SP3_RS05150 6ad53d209b501758a2890cc6eea093af 169 Gene3D G3DSA:3.40.220.10 4 166 4.9E-68 T 09-03-2017 L21SP3_RS05785 5ab29664fa41b0a5ad4d6add99848555 142 SUPERFAMILY SSF55620 23 140 4.67E-19 T 09-03-2017 L21SP3_RS05785 5ab29664fa41b0a5ad4d6add99848555 142 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 27 141 1.5E-18 T 09-03-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 L21SP3_RS05785 5ab29664fa41b0a5ad4d6add99848555 142 Gene3D G3DSA:3.30.479.10 23 141 1.0E-21 T 09-03-2017 L21SP3_RS07885 07ee1b0bfa3fb785ff6e1a5810583ee6 145 Pfam PF02502 Ribose/Galactose Isomerase 3 139 1.2E-52 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 L21SP3_RS07885 07ee1b0bfa3fb785ff6e1a5810583ee6 145 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 142 8.2E-49 T 09-03-2017 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 L21SP3_RS07885 07ee1b0bfa3fb785ff6e1a5810583ee6 145 PIRSF PIRSF005384 1 145 8.0E-55 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 L21SP3_RS07885 07ee1b0bfa3fb785ff6e1a5810583ee6 145 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 142 3.3E-51 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 L21SP3_RS07885 07ee1b0bfa3fb785ff6e1a5810583ee6 145 SUPERFAMILY SSF89623 1 143 1.57E-53 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 L21SP3_RS07885 07ee1b0bfa3fb785ff6e1a5810583ee6 145 Gene3D G3DSA:3.40.1400.10 1 143 5.1E-59 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 L21SP3_RS10020 2439769596cd6ccb12b78317276f5492 323 Pfam PF13936 Helix-turn-helix domain 3 45 5.0E-15 T 09-03-2017 IPR025246 Transposase IS30-like HTH domain L21SP3_RS10020 2439769596cd6ccb12b78317276f5492 323 Pfam PF00665 Integrase core domain 178 280 4.4E-10 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS10020 2439769596cd6ccb12b78317276f5492 323 SUPERFAMILY SSF53098 176 321 8.91E-25 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS10020 2439769596cd6ccb12b78317276f5492 323 ProSitePatterns PS01043 Transposases, IS30 family, signature. 268 284 - T 09-03-2017 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 L21SP3_RS10020 2439769596cd6ccb12b78317276f5492 323 Gene3D G3DSA:3.30.420.10 178 320 9.6E-12 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS09145 2439769596cd6ccb12b78317276f5492 323 Pfam PF13936 Helix-turn-helix domain 3 45 5.0E-15 T 09-03-2017 IPR025246 Transposase IS30-like HTH domain L21SP3_RS09145 2439769596cd6ccb12b78317276f5492 323 Pfam PF00665 Integrase core domain 178 280 4.4E-10 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS09145 2439769596cd6ccb12b78317276f5492 323 SUPERFAMILY SSF53098 176 321 8.91E-25 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS09145 2439769596cd6ccb12b78317276f5492 323 ProSitePatterns PS01043 Transposases, IS30 family, signature. 268 284 - T 09-03-2017 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 L21SP3_RS09145 2439769596cd6ccb12b78317276f5492 323 Gene3D G3DSA:3.30.420.10 178 320 9.6E-12 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS08055 30c93e7e82ffd5b7b1a4c4eb3369ded9 427 Gene3D G3DSA:3.40.440.10 195 265 2.0E-65 T 09-03-2017 L21SP3_RS08055 30c93e7e82ffd5b7b1a4c4eb3369ded9 427 Gene3D G3DSA:3.40.440.10 3 92 2.0E-65 T 09-03-2017 L21SP3_RS08055 30c93e7e82ffd5b7b1a4c4eb3369ded9 427 Pfam PF00709 Adenylosuccinate synthetase 4 422 2.5E-172 T 09-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 L21SP3_RS08055 30c93e7e82ffd5b7b1a4c4eb3369ded9 427 SMART SM00788 2 423 4.2E-259 T 09-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 L21SP3_RS08055 30c93e7e82ffd5b7b1a4c4eb3369ded9 427 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 9 16 - T 09-03-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 L21SP3_RS08055 30c93e7e82ffd5b7b1a4c4eb3369ded9 427 SUPERFAMILY SSF52540 2 425 9.14E-162 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08055 30c93e7e82ffd5b7b1a4c4eb3369ded9 427 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 427 182.462 T 09-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 L21SP3_RS08055 30c93e7e82ffd5b7b1a4c4eb3369ded9 427 Gene3D G3DSA:3.90.170.10 266 423 5.3E-66 T 09-03-2017 L21SP3_RS08055 30c93e7e82ffd5b7b1a4c4eb3369ded9 427 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 09-03-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 L21SP3_RS08055 30c93e7e82ffd5b7b1a4c4eb3369ded9 427 Gene3D G3DSA:1.10.300.10 100 194 1.8E-30 T 09-03-2017 L21SP3_RS08055 30c93e7e82ffd5b7b1a4c4eb3369ded9 427 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 422 2.4E-158 T 09-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 L21SP3_RS01980 3c32ce50bcc514c22016bd5350ea4814 280 Gene3D G3DSA:3.20.20.80 105 239 5.6E-17 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS01980 3c32ce50bcc514c22016bd5350ea4814 280 SUPERFAMILY SSF51445 60 247 1.23E-22 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS01980 3c32ce50bcc514c22016bd5350ea4814 280 Pfam PF11790 Glycosyl hydrolase catalytic core 52 274 6.7E-53 T 09-03-2017 IPR024655 Uncharacterised protein family, glycosyl hydrolase catalytic domain L21SP3_RS10195 07dd4506f2dedc20fb5df022e7567dd1 687 Pfam PF00905 Penicillin binding protein transpeptidase domain 340 676 1.0E-40 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 L21SP3_RS10195 07dd4506f2dedc20fb5df022e7567dd1 687 Gene3D G3DSA:3.90.1310.10 218 318 3.9E-15 T 09-03-2017 L21SP3_RS10195 07dd4506f2dedc20fb5df022e7567dd1 687 SUPERFAMILY SSF56601 313 501 3.22E-55 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like L21SP3_RS10195 07dd4506f2dedc20fb5df022e7567dd1 687 SUPERFAMILY SSF56601 533 680 3.22E-55 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like L21SP3_RS10195 07dd4506f2dedc20fb5df022e7567dd1 687 Pfam PF03717 Penicillin-binding Protein dimerisation domain 51 292 5.9E-18 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 L21SP3_RS10195 07dd4506f2dedc20fb5df022e7567dd1 687 Gene3D G3DSA:3.40.710.10 319 680 3.8E-62 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like L21SP3_RS10195 07dd4506f2dedc20fb5df022e7567dd1 687 SUPERFAMILY SSF56519 48 81 1.06E-18 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 L21SP3_RS10195 07dd4506f2dedc20fb5df022e7567dd1 687 SUPERFAMILY SSF56519 194 312 1.06E-18 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 L21SP3_RS00795 acc49956d0a64da54fd8dc39545cba10 481 SUPERFAMILY SSF53649 33 456 6.67E-115 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS00795 acc49956d0a64da54fd8dc39545cba10 481 Gene3D G3DSA:3.40.720.10 33 404 9.1E-104 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS00795 acc49956d0a64da54fd8dc39545cba10 481 Pfam PF00884 Sulfatase 35 367 6.4E-59 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS00795 acc49956d0a64da54fd8dc39545cba10 481 Gene3D G3DSA:3.30.1120.10 405 464 2.6E-12 T 09-03-2017 L21SP3_RS02305 f1e2ea9a4bb6deb5e68375e746398add 177 Gene3D G3DSA:3.30.420.10 29 174 4.5E-9 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS02305 f1e2ea9a4bb6deb5e68375e746398add 177 Pfam PF13358 DDE superfamily endonuclease 15 160 1.2E-20 T 09-03-2017 L21SP3_RS02305 f1e2ea9a4bb6deb5e68375e746398add 177 SUPERFAMILY SSF53098 22 173 1.19E-10 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS07505 6a3beaf7e79fb84e47869be41b1b655f 488 ProSitePatterns PS00523 Sulfatases signature 1. 101 113 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS07505 6a3beaf7e79fb84e47869be41b1b655f 488 Pfam PF00884 Sulfatase 55 386 3.6E-71 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS07505 6a3beaf7e79fb84e47869be41b1b655f 488 Gene3D G3DSA:3.40.720.10 55 422 2.9E-115 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS07505 6a3beaf7e79fb84e47869be41b1b655f 488 SUPERFAMILY SSF53649 55 480 4.36E-132 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS07505 6a3beaf7e79fb84e47869be41b1b655f 488 Gene3D G3DSA:3.30.1120.10 423 484 3.8E-17 T 09-03-2017 L21SP3_RS02280 493106f73149c683ee60362b60045773 784 Pfam PF00703 Glycosyl hydrolases family 2 263 310 2.1E-12 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS02280 493106f73149c683ee60362b60045773 784 Gene3D G3DSA:2.60.120.260 44 204 1.8E-56 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS02280 493106f73149c683ee60362b60045773 784 Gene3D G3DSA:2.60.120.260 602 736 2.6E-10 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS02280 493106f73149c683ee60362b60045773 784 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 90 210 2.7E-16 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS02280 493106f73149c683ee60362b60045773 784 SUPERFAMILY SSF49785 602 742 5.67E-12 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS02280 493106f73149c683ee60362b60045773 784 SUPERFAMILY SSF49303 218 311 2.27E-14 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS02280 493106f73149c683ee60362b60045773 784 Gene3D G3DSA:3.20.20.80 309 574 1.2E-55 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS02280 493106f73149c683ee60362b60045773 784 Gene3D G3DSA:2.60.40.320 205 308 2.1E-23 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS02280 493106f73149c683ee60362b60045773 784 SUPERFAMILY SSF49785 44 215 1.21E-48 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS02280 493106f73149c683ee60362b60045773 784 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 352 476 7.9E-10 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS02280 493106f73149c683ee60362b60045773 784 SUPERFAMILY SSF51445 307 574 2.65E-64 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS06190 8beb08407b6daf7585dd49ed9461aab5 87 Gene3D G3DSA:3.30.860.10 1 85 5.6E-39 T 09-03-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06190 8beb08407b6daf7585dd49ed9461aab5 87 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.2E-23 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06190 8beb08407b6daf7585dd49ed9461aab5 87 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.2E-23 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06190 8beb08407b6daf7585dd49ed9461aab5 87 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.2E-23 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06190 8beb08407b6daf7585dd49ed9461aab5 87 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 87 24.455 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06190 8beb08407b6daf7585dd49ed9461aab5 87 Pfam PF00203 Ribosomal protein S19 3 83 2.1E-36 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06190 8beb08407b6daf7585dd49ed9461aab5 87 PIRSF PIRSF002144 1 87 1.7E-31 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06190 8beb08407b6daf7585dd49ed9461aab5 87 SUPERFAMILY SSF54570 3 84 1.11E-33 T 09-03-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06190 8beb08407b6daf7585dd49ed9461aab5 87 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 85 1.5E-43 T 09-03-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 L21SP3_RS06190 8beb08407b6daf7585dd49ed9461aab5 87 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 09-03-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS04680 f02e072d7425ae31ee6985d4a8d877ab 143 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 7 139 2.7E-43 T 09-03-2017 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 L21SP3_RS04680 f02e072d7425ae31ee6985d4a8d877ab 143 PRINTS PR00813 Bacterial general secretion pathway protein G signature 8 33 2.1E-13 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS04680 f02e072d7425ae31ee6985d4a8d877ab 143 PRINTS PR00813 Bacterial general secretion pathway protein G signature 44 62 2.1E-13 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS04680 f02e072d7425ae31ee6985d4a8d877ab 143 Pfam PF13633 Prokaryotic N-terminal methylation site 7 31 1.5E-9 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS04680 f02e072d7425ae31ee6985d4a8d877ab 143 SUPERFAMILY SSF54523 35 138 3.51E-28 T 09-03-2017 L21SP3_RS04680 f02e072d7425ae31ee6985d4a8d877ab 143 Pfam PF08334 Type II secretion system (T2SS), protein G 32 138 1.0E-34 T 09-03-2017 IPR013545 Type II secretion system protein G L21SP3_RS04680 f02e072d7425ae31ee6985d4a8d877ab 143 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 28 2.5E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS04680 f02e072d7425ae31ee6985d4a8d877ab 143 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 7 27 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS04680 f02e072d7425ae31ee6985d4a8d877ab 143 Gene3D G3DSA:3.30.700.10 9 74 5.3E-8 T 09-03-2017 L21SP3_RS06520 aa92433b366c7071d4bdf2e53dba248c 392 SUPERFAMILY SSF52172 5 172 4.41E-39 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS06520 aa92433b366c7071d4bdf2e53dba248c 392 Gene3D G3DSA:1.10.287.130 157 213 1.0E-11 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS06520 aa92433b366c7071d4bdf2e53dba248c 392 Pfam PF00072 Response regulator receiver domain 9 120 1.5E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS06520 aa92433b366c7071d4bdf2e53dba248c 392 SUPERFAMILY SSF55874 253 382 1.26E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS06520 aa92433b366c7071d4bdf2e53dba248c 392 Gene3D G3DSA:3.30.565.10 214 383 3.3E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS06520 aa92433b366c7071d4bdf2e53dba248c 392 Gene3D G3DSA:3.40.50.2300 5 137 1.1E-39 T 09-03-2017 L21SP3_RS06520 aa92433b366c7071d4bdf2e53dba248c 392 SMART SM00388 164 229 1.4E-8 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS06520 aa92433b366c7071d4bdf2e53dba248c 392 SUPERFAMILY SSF47384 149 226 7.85E-14 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS06520 aa92433b366c7071d4bdf2e53dba248c 392 Pfam PF00512 His Kinase A (phospho-acceptor) domain 164 224 1.6E-9 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS06520 aa92433b366c7071d4bdf2e53dba248c 392 SMART SM00448 7 120 8.1E-39 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 7 444 4.3E-147 T 09-03-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 397 443 2.7E-9 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 SUPERFAMILY SSF53738 3 136 3.41E-40 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 Gene3D G3DSA:3.30.310.50 363 444 7.7E-13 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 SUPERFAMILY SSF53738 260 368 1.02E-27 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 09-03-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 3 447 38.867 T 09-03-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 SUPERFAMILY SSF53738 170 259 5.49E-23 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 136 1.9E-40 T 09-03-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 367 3.5E-29 T 09-03-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 171 256 1.6E-15 T 09-03-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 SUPERFAMILY SSF55957 360 446 9.03E-17 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 Gene3D G3DSA:3.40.120.10 178 250 5.0E-22 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 1.7E-15 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 176 195 1.7E-15 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 1.7E-15 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 Gene3D G3DSA:3.40.120.10 4 137 3.2E-42 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS03395 cb9776b1bfdac0c44ffe1386efaa608e 448 Gene3D G3DSA:3.40.120.10 253 362 3.1E-32 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 L21SP3_RS08515 99709029c9dc2ff73f431a485a8bd41b 336 Gene3D G3DSA:1.10.1610.10 5 58 1.7E-26 T 09-03-2017 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 L21SP3_RS08515 99709029c9dc2ff73f431a485a8bd41b 336 Pfam PF02277 Phosphoribosyltransferase 5 334 9.9E-122 T 09-03-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 L21SP3_RS08515 99709029c9dc2ff73f431a485a8bd41b 336 Gene3D G3DSA:3.40.50.10210 59 317 6.7E-98 T 09-03-2017 L21SP3_RS08515 99709029c9dc2ff73f431a485a8bd41b 336 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 1 336 31.151 T 09-03-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 L21SP3_RS08515 99709029c9dc2ff73f431a485a8bd41b 336 SUPERFAMILY SSF52733 5 335 1.57E-101 T 09-03-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 L21SP3_RS08515 99709029c9dc2ff73f431a485a8bd41b 336 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 5 334 2.2E-118 T 09-03-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 L21SP3_RS01105 59f575c55e3225a9156fff29cbefb277 425 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 332 3.2E-19 T 09-03-2017 IPR003395 RecF/RecN/SMC, N-terminal L21SP3_RS01105 59f575c55e3225a9156fff29cbefb277 425 SUPERFAMILY SSF52540 1 332 1.82E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01105 59f575c55e3225a9156fff29cbefb277 425 Gene3D G3DSA:3.40.1140.10 245 336 1.8E-36 T 09-03-2017 L21SP3_RS01105 59f575c55e3225a9156fff29cbefb277 425 Gene3D G3DSA:3.40.1140.10 1 100 1.8E-36 T 09-03-2017 L21SP3_RS09975 4bc71df75fa6fac8ad49bc87435d4b8a 368 Pfam PF13528 Glycosyl transferase family 1 2 320 2.9E-75 T 09-03-2017 L21SP3_RS09975 4bc71df75fa6fac8ad49bc87435d4b8a 368 SUPERFAMILY SSF53756 1 322 2.86E-14 T 09-03-2017 L21SP3_RS09975 4bc71df75fa6fac8ad49bc87435d4b8a 368 Gene3D G3DSA:3.40.50.2000 8 123 3.5E-5 T 09-03-2017 L21SP3_RS00085 71390b185fd1f7c2c77c6fefc349a2d1 228 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 23 228 19.128 T 09-03-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 L21SP3_RS00085 71390b185fd1f7c2c77c6fefc349a2d1 228 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 21 226 7.4E-47 T 09-03-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 L21SP3_RS00085 71390b185fd1f7c2c77c6fefc349a2d1 228 Pfam PF02660 Glycerol-3-phosphate acyltransferase 27 219 4.1E-50 T 09-03-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 L21SP3_RS00085 71390b185fd1f7c2c77c6fefc349a2d1 228 SMART SM01207 26 220 1.5E-65 T 09-03-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 L21SP3_RS01095 4a5432d3f9bfdcc9a2148f5c9742e395 270 SUPERFAMILY SSF52402 3 206 6.75E-62 T 09-03-2017 L21SP3_RS01095 4a5432d3f9bfdcc9a2148f5c9742e395 270 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 28 224 5.2E-44 T 09-03-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 L21SP3_RS01095 4a5432d3f9bfdcc9a2148f5c9742e395 270 Gene3D G3DSA:3.40.50.620 4 220 2.8E-58 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS03290 8b94c40e3d9ecaa86bb0a19e07d5b82c 184 Pfam PF12844 Helix-turn-helix domain 10 70 2.1E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP3_RS03290 8b94c40e3d9ecaa86bb0a19e07d5b82c 184 SMART SM00530 11 66 1.5E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP3_RS03290 8b94c40e3d9ecaa86bb0a19e07d5b82c 184 Gene3D G3DSA:1.10.260.40 8 106 1.6E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS03290 8b94c40e3d9ecaa86bb0a19e07d5b82c 184 SUPERFAMILY SSF51182 77 183 3.61E-26 T 09-03-2017 IPR011051 RmlC-like cupin domain L21SP3_RS03290 8b94c40e3d9ecaa86bb0a19e07d5b82c 184 Pfam PF07883 Cupin domain 118 182 8.6E-14 T 09-03-2017 IPR013096 Cupin 2, conserved barrel L21SP3_RS03290 8b94c40e3d9ecaa86bb0a19e07d5b82c 184 Gene3D G3DSA:2.60.120.10 107 183 2.4E-21 T 09-03-2017 IPR014710 RmlC-like jelly roll fold L21SP3_RS03290 8b94c40e3d9ecaa86bb0a19e07d5b82c 184 SUPERFAMILY SSF47413 5 71 4.35E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS05800 2a59a46e3b40c315684b04420c38ba38 397 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 4 381 5.2E-102 T 09-03-2017 IPR002822 Uncharacterised protein family UPF0272 L21SP3_RS05800 2a59a46e3b40c315684b04420c38ba38 397 Hamap MF_01074 UPF0272 protein . 1 397 34.959 T 09-03-2017 IPR002822 Uncharacterised protein family UPF0272 L21SP3_RS05800 2a59a46e3b40c315684b04420c38ba38 397 Gene3D G3DSA:3.30.70.1380 251 339 7.3E-26 T 09-03-2017 L21SP3_RS05800 2a59a46e3b40c315684b04420c38ba38 397 Gene3D G3DSA:3.10.20.300 340 386 3.6E-8 T 09-03-2017 L21SP3_RS05800 2a59a46e3b40c315684b04420c38ba38 397 Pfam PF01969 Protein of unknown function DUF111 5 384 2.2E-126 T 09-03-2017 IPR002822 Uncharacterised protein family UPF0272 L21SP3_RS11310 e5f53fc37da7efb18d01cd3077ed1434 1514 Pfam PF04898 Glutamate synthase central domain 465 752 1.6E-103 T 09-03-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 L21SP3_RS11310 e5f53fc37da7efb18d01cd3077ed1434 1514 Pfam PF01493 GXGXG motif 1261 1446 1.7E-78 T 09-03-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 L21SP3_RS11310 e5f53fc37da7efb18d01cd3077ed1434 1514 SUPERFAMILY SSF51395 451 1215 3.48E-241 T 09-03-2017 L21SP3_RS11310 e5f53fc37da7efb18d01cd3077ed1434 1514 Pfam PF01645 Conserved region in glutamate synthase 815 1179 1.1E-151 T 09-03-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 L21SP3_RS11310 e5f53fc37da7efb18d01cd3077ed1434 1514 Gene3D G3DSA:2.160.20.60 1234 1504 1.6E-102 T 09-03-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 L21SP3_RS11310 e5f53fc37da7efb18d01cd3077ed1434 1514 Pfam PF00310 Glutamine amidotransferases class-II 20 436 4.2E-173 T 09-03-2017 IPR017932 Glutamine amidotransferase type 2 domain L21SP3_RS11310 e5f53fc37da7efb18d01cd3077ed1434 1514 SUPERFAMILY SSF69336 1231 1493 1.83E-94 T 09-03-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 L21SP3_RS11310 e5f53fc37da7efb18d01cd3077ed1434 1514 Gene3D G3DSA:3.60.20.10 20 445 1.4E-175 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP3_RS11310 e5f53fc37da7efb18d01cd3077ed1434 1514 SUPERFAMILY SSF56235 20 438 2.04E-145 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP3_RS11310 e5f53fc37da7efb18d01cd3077ed1434 1514 Gene3D G3DSA:3.20.20.70 457 800 7.4E-93 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS11310 e5f53fc37da7efb18d01cd3077ed1434 1514 Gene3D G3DSA:3.20.20.70 846 1219 7.6E-175 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS04215 b96916f7f5ed5fb69ab60d9c90d7844a 290 Hamap MF_00082_B Acetylglutamate kinase [argB]. 22 290 30.822 T 09-03-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 L21SP3_RS04215 b96916f7f5ed5fb69ab60d9c90d7844a 290 PIRSF PIRSF000728 8 290 7.7E-91 T 09-03-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 L21SP3_RS04215 b96916f7f5ed5fb69ab60d9c90d7844a 290 Gene3D G3DSA:3.40.1160.10 23 289 7.7E-81 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase L21SP3_RS04215 b96916f7f5ed5fb69ab60d9c90d7844a 290 SUPERFAMILY SSF53633 2 289 2.75E-71 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase L21SP3_RS04215 b96916f7f5ed5fb69ab60d9c90d7844a 290 TIGRFAM TIGR00761 argB: acetylglutamate kinase 26 265 1.1E-67 T 09-03-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 L21SP3_RS04215 b96916f7f5ed5fb69ab60d9c90d7844a 290 Pfam PF00696 Amino acid kinase family 25 267 2.4E-39 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase L21SP3_RS00400 f55e7300ff1470127c1a4d0261f682ee 239 Gene3D G3DSA:3.40.109.10 45 236 1.7E-34 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 L21SP3_RS00400 f55e7300ff1470127c1a4d0261f682ee 239 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 76 238 2.2E-46 T 09-03-2017 IPR020051 SagB-type dehydrogenase domain L21SP3_RS00400 f55e7300ff1470127c1a4d0261f682ee 239 Pfam PF00881 Nitroreductase family 61 237 4.4E-31 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 L21SP3_RS00400 f55e7300ff1470127c1a4d0261f682ee 239 SUPERFAMILY SSF55469 54 237 3.38E-33 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 L21SP3_RS00340 68b9e54139adc76a60c0f29944f040c8 447 TIGRFAM TIGR00260 thrC: threonine synthase 68 414 8.3E-70 T 09-03-2017 IPR004450 Threonine synthase-like L21SP3_RS00340 68b9e54139adc76a60c0f29944f040c8 447 Gene3D G3DSA:3.40.50.1100 79 167 1.3E-6 T 09-03-2017 L21SP3_RS00340 68b9e54139adc76a60c0f29944f040c8 447 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 85 407 4.8E-55 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP3_RS00340 68b9e54139adc76a60c0f29944f040c8 447 PIRSF PIRSF038945 50 437 7.7E-108 T 09-03-2017 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 L21SP3_RS00340 68b9e54139adc76a60c0f29944f040c8 447 Gene3D G3DSA:3.40.50.1100 168 444 8.9E-50 T 09-03-2017 L21SP3_RS00340 68b9e54139adc76a60c0f29944f040c8 447 SUPERFAMILY SSF53686 6 445 6.29E-81 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP3_RS00940 6f9604a222ae0a011a18448876a77ecc 339 Gene3D G3DSA:3.90.550.10 5 231 3.8E-48 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS00940 6f9604a222ae0a011a18448876a77ecc 339 SUPERFAMILY SSF53448 6 211 1.35E-49 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS00940 6f9604a222ae0a011a18448876a77ecc 339 Pfam PF00535 Glycosyl transferase family 2 8 140 2.9E-34 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 L21SP3_RS08475 7dfa302b0487eb8bbb641462d550f621 176 Pfam PF12641 Flavodoxin domain 5 163 4.7E-52 T 09-03-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 L21SP3_RS08475 7dfa302b0487eb8bbb641462d550f621 176 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 09-03-2017 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 L21SP3_RS08475 7dfa302b0487eb8bbb641462d550f621 176 Gene3D G3DSA:3.40.50.360 1 171 1.2E-21 T 09-03-2017 IPR029039 Flavoprotein-like domain L21SP3_RS08475 7dfa302b0487eb8bbb641462d550f621 176 SUPERFAMILY SSF52218 1 114 2.51E-16 T 09-03-2017 IPR029039 Flavoprotein-like domain L21SP3_RS02855 d26cbd5e27449191def32027202b5704 355 SUPERFAMILY SSF53613 4 344 3.59E-47 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS02855 d26cbd5e27449191def32027202b5704 355 Gene3D G3DSA:3.40.1190.20 2 349 2.4E-58 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS02855 d26cbd5e27449191def32027202b5704 355 Pfam PF00294 pfkB family carbohydrate kinase 40 329 1.8E-18 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 Pfam PF13229 Right handed beta helix region 1218 1369 1.0E-9 T 09-03-2017 L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 SUPERFAMILY SSF51126 1033 1182 2.16E-35 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 SUPERFAMILY SSF51126 1214 1369 2.16E-35 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 Gene3D G3DSA:2.160.20.10 1201 1548 4.2E-37 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 Gene3D G3DSA:2.160.20.10 1036 1144 4.2E-37 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 SUPERFAMILY SSF51126 1294 1548 3.93E-13 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 SUPERFAMILY SSF63446 982 1032 5.89E-5 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 SMART SM00710 1346 1374 9100.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 SMART SM00710 1130 1163 2800.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 SMART SM00710 1400 1424 840.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 SMART SM00710 1215 1237 890.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 SMART SM00710 1270 1302 82.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 SMART SM00710 1247 1269 320.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 SMART SM00710 1303 1329 3100.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08855 1499068ed8c9146030ba80e0219a5807 1550 SUPERFAMILY SSF50998 42 344 3.92E-6 T 09-03-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily L21SP3_RS04125 69aae11cdff9a883cbf14d6c50186453 81 PRINTS PR00063 Ribosomal protein L27 signature 29 53 7.3E-32 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS04125 69aae11cdff9a883cbf14d6c50186453 81 PRINTS PR00063 Ribosomal protein L27 signature 4 28 7.3E-32 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS04125 69aae11cdff9a883cbf14d6c50186453 81 PRINTS PR00063 Ribosomal protein L27 signature 54 78 7.3E-32 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS04125 69aae11cdff9a883cbf14d6c50186453 81 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 70 3.0E-11 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS04125 69aae11cdff9a883cbf14d6c50186453 81 SUPERFAMILY SSF110324 2 75 6.28E-31 T 09-03-2017 L21SP3_RS04125 69aae11cdff9a883cbf14d6c50186453 81 Gene3D G3DSA:2.40.50.100 21 74 9.9E-26 T 09-03-2017 L21SP3_RS04125 69aae11cdff9a883cbf14d6c50186453 81 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 81 24.397 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS04125 69aae11cdff9a883cbf14d6c50186453 81 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 72 1.7E-30 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS04125 69aae11cdff9a883cbf14d6c50186453 81 Pfam PF01016 Ribosomal L27 protein 2 72 2.5E-34 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS04445 8fb8b77bedaaf15be326d746d8005e8d 507 Gene3D G3DSA:3.40.50.300 95 372 1.7E-107 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04445 8fb8b77bedaaf15be326d746d8005e8d 507 SUPERFAMILY SSF47917 374 501 8.89E-40 T 09-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS04445 8fb8b77bedaaf15be326d746d8005e8d 507 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 372 495 7.0E-43 T 09-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS04445 8fb8b77bedaaf15be326d746d8005e8d 507 SUPERFAMILY SSF50615 10 94 6.8E-26 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS04445 8fb8b77bedaaf15be326d746d8005e8d 507 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 501 2.0E-229 T 09-03-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 L21SP3_RS04445 8fb8b77bedaaf15be326d746d8005e8d 507 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 356 365 - T 09-03-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS04445 8fb8b77bedaaf15be326d746d8005e8d 507 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 502 47.177 T 09-03-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 L21SP3_RS04445 8fb8b77bedaaf15be326d746d8005e8d 507 Gene3D G3DSA:2.40.30.20 1 93 1.7E-31 T 09-03-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 L21SP3_RS04445 8fb8b77bedaaf15be326d746d8005e8d 507 SUPERFAMILY SSF52540 96 371 7.82E-91 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04445 8fb8b77bedaaf15be326d746d8005e8d 507 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 365 2.0E-68 T 09-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS04445 8fb8b77bedaaf15be326d746d8005e8d 507 Gene3D G3DSA:1.20.150.20 374 500 9.1E-43 T 09-03-2017 L21SP3_RS04445 8fb8b77bedaaf15be326d746d8005e8d 507 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 3.9E-16 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS08190 62cba04284300a860e572cebcc6e8017 488 Gene3D G3DSA:3.40.720.10 31 390 4.4E-131 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08190 62cba04284300a860e572cebcc6e8017 488 ProSitePatterns PS00149 Sulfatases signature 2. 124 134 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS08190 62cba04284300a860e572cebcc6e8017 488 SUPERFAMILY SSF53649 32 475 1.18E-144 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS08190 62cba04284300a860e572cebcc6e8017 488 Pfam PF16347 Domain of unknown function (DUF4976) 373 475 3.1E-47 T 09-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 L21SP3_RS08190 62cba04284300a860e572cebcc6e8017 488 Gene3D G3DSA:3.30.1120.10 400 476 8.1E-20 T 09-03-2017 L21SP3_RS08190 62cba04284300a860e572cebcc6e8017 488 Pfam PF00884 Sulfatase 34 370 9.8E-71 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS08190 62cba04284300a860e572cebcc6e8017 488 ProSitePatterns PS00523 Sulfatases signature 1. 80 92 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS03385 c5c5fb93f2237d32a8456462d3856510 270 SUPERFAMILY SSF48452 124 243 4.74E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS03385 c5c5fb93f2237d32a8456462d3856510 270 Gene3D G3DSA:1.25.40.10 124 242 1.2E-12 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS03385 c5c5fb93f2237d32a8456462d3856510 270 Pfam PF13181 Tetratricopeptide repeat 173 203 5.1E-4 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS03385 c5c5fb93f2237d32a8456462d3856510 270 Pfam PF13181 Tetratricopeptide repeat 208 236 0.052 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS04910 45fef1505e556e2120a5e202d79165f6 209 Pfam PF13580 SIS domain 29 166 3.9E-33 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 L21SP3_RS04910 45fef1505e556e2120a5e202d79165f6 209 SUPERFAMILY SSF53697 24 207 3.84E-48 T 09-03-2017 L21SP3_RS04910 45fef1505e556e2120a5e202d79165f6 209 Gene3D G3DSA:3.40.50.10490 24 207 3.0E-56 T 09-03-2017 L21SP3_RS01945 b6b4afafdee20e9d9b3efe7cd6691072 979 Gene3D G3DSA:3.20.20.80 47 348 3.0E-21 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS01945 b6b4afafdee20e9d9b3efe7cd6691072 979 SUPERFAMILY SSF49785 794 919 1.7E-16 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01945 b6b4afafdee20e9d9b3efe7cd6691072 979 Gene3D G3DSA:2.60.40.1180 349 445 5.6E-8 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta L21SP3_RS01945 b6b4afafdee20e9d9b3efe7cd6691072 979 Pfam PF00754 F5/8 type C domain 803 911 8.5E-12 T 09-03-2017 IPR000421 Coagulation factor 5/8 C-terminal domain L21SP3_RS01945 b6b4afafdee20e9d9b3efe7cd6691072 979 SUPERFAMILY SSF51445 46 357 2.69E-21 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS01945 b6b4afafdee20e9d9b3efe7cd6691072 979 PRINTS PR00850 Glycosyl hydrolase family 59 signature 271 295 9.4E-5 T 09-03-2017 IPR001286 Glycoside hydrolase, family 59 GO:0004336|GO:0006683 KEGG: 00600+3.2.1.46|Reactome: R-HSA-1660662 L21SP3_RS01945 b6b4afafdee20e9d9b3efe7cd6691072 979 PRINTS PR00850 Glycosyl hydrolase family 59 signature 349 373 9.4E-5 T 09-03-2017 IPR001286 Glycoside hydrolase, family 59 GO:0004336|GO:0006683 KEGG: 00600+3.2.1.46|Reactome: R-HSA-1660662 L21SP3_RS01945 b6b4afafdee20e9d9b3efe7cd6691072 979 PRINTS PR00850 Glycosyl hydrolase family 59 signature 107 131 9.4E-5 T 09-03-2017 IPR001286 Glycoside hydrolase, family 59 GO:0004336|GO:0006683 KEGG: 00600+3.2.1.46|Reactome: R-HSA-1660662 L21SP3_RS01945 b6b4afafdee20e9d9b3efe7cd6691072 979 Pfam PF02057 Glycosyl hydrolase family 59 21 378 1.6E-60 T 09-03-2017 IPR001286 Glycoside hydrolase, family 59 GO:0004336|GO:0006683 KEGG: 00600+3.2.1.46|Reactome: R-HSA-1660662 L21SP3_RS01945 b6b4afafdee20e9d9b3efe7cd6691072 979 Pfam PF02057 Glycosyl hydrolase family 59 429 659 2.2E-9 T 09-03-2017 IPR001286 Glycoside hydrolase, family 59 GO:0004336|GO:0006683 KEGG: 00600+3.2.1.46|Reactome: R-HSA-1660662 L21SP3_RS01945 b6b4afafdee20e9d9b3efe7cd6691072 979 Gene3D G3DSA:2.60.120.260 793 919 3.3E-15 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS08405 0650b1f461f69a861ec1e34e70908b6f 240 Pfam PF07589 PEP-CTERM motif 219 239 6.0E-6 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS08405 0650b1f461f69a861ec1e34e70908b6f 240 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 219 240 9.1E-6 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS00490 bf77a979e9b2ccca40c59ce74639852d 361 SUPERFAMILY SSF53448 1 281 2.1E-64 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS00490 bf77a979e9b2ccca40c59ce74639852d 361 Gene3D G3DSA:3.90.550.10 4 273 2.6E-84 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS00490 bf77a979e9b2ccca40c59ce74639852d 361 Pfam PF00483 Nucleotidyl transferase 5 288 5.7E-47 T 09-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 L21SP3_RS00490 bf77a979e9b2ccca40c59ce74639852d 361 SUPERFAMILY SSF159283 286 353 2.48E-12 T 09-03-2017 L21SP3_RS05360 29eb06e24fa883d6dd1655d3f1c64153 721 SUPERFAMILY SSF56784 490 720 6.57E-42 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS05360 29eb06e24fa883d6dd1655d3f1c64153 721 Pfam PF00982 Glycosyltransferase family 20 3 458 7.1E-154 T 09-03-2017 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 L21SP3_RS05360 29eb06e24fa883d6dd1655d3f1c64153 721 SUPERFAMILY SSF53756 2 460 6.91E-145 T 09-03-2017 L21SP3_RS05360 29eb06e24fa883d6dd1655d3f1c64153 721 Pfam PF02358 Trehalose-phosphatase 493 693 6.9E-53 T 09-03-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 L21SP3_RS05360 29eb06e24fa883d6dd1655d3f1c64153 721 Gene3D G3DSA:3.40.50.2000 1 245 1.2E-89 T 09-03-2017 L21SP3_RS05360 29eb06e24fa883d6dd1655d3f1c64153 721 Gene3D G3DSA:3.40.50.1000 645 720 2.8E-42 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS05360 29eb06e24fa883d6dd1655d3f1c64153 721 Gene3D G3DSA:3.40.50.1000 489 565 2.8E-42 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS05360 29eb06e24fa883d6dd1655d3f1c64153 721 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 491 689 1.0E-23 T 09-03-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 L21SP3_RS05360 29eb06e24fa883d6dd1655d3f1c64153 721 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 488 720 1.8E-41 T 09-03-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 L21SP3_RS05360 29eb06e24fa883d6dd1655d3f1c64153 721 Gene3D G3DSA:3.40.50.2000 258 442 5.1E-72 T 09-03-2017 L21SP3_RS01680 cf5e3c0e8920bb575829ac9007c60c38 158 SUPERFAMILY SSF118196 1 147 8.89E-54 T 09-03-2017 IPR023370 TsaA-like domain L21SP3_RS01680 cf5e3c0e8920bb575829ac9007c60c38 158 Pfam PF01980 Uncharacterised protein family UPF0066 21 132 9.3E-38 T 09-03-2017 IPR023370 TsaA-like domain L21SP3_RS01680 cf5e3c0e8920bb575829ac9007c60c38 158 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 2 133 2.9E-42 T 09-03-2017 IPR023370 TsaA-like domain L21SP3_RS01680 cf5e3c0e8920bb575829ac9007c60c38 158 Gene3D G3DSA:2.40.30.70 4 146 3.1E-52 T 09-03-2017 IPR023370 TsaA-like domain L21SP3_RS01680 cf5e3c0e8920bb575829ac9007c60c38 158 ProSitePatterns PS01318 TsaA-like domain signature. 81 92 - T 09-03-2017 IPR023368 Uncharacterised protein family UPF0066, conserved site L21SP3_RS08945 5c8ed532aed0f22f6a4f3fffddcbe2ff 277 Gene3D G3DSA:3.40.50.1820 48 260 8.6E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08945 5c8ed532aed0f22f6a4f3fffddcbe2ff 277 SUPERFAMILY SSF53474 51 261 1.3E-36 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08945 5c8ed532aed0f22f6a4f3fffddcbe2ff 277 Pfam PF07859 alpha/beta hydrolase fold 66 147 3.3E-14 T 09-03-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 L21SP3_RS06475 dff003a87c8d67381eae85467cadc6ae 626 SUPERFAMILY SSF51445 49 385 2.7E-100 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS06475 dff003a87c8d67381eae85467cadc6ae 626 PRINTS PR00741 Glycosyl hydrolase family 29 signature 368 390 4.6E-17 T 09-03-2017 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 L21SP3_RS06475 dff003a87c8d67381eae85467cadc6ae 626 PRINTS PR00741 Glycosyl hydrolase family 29 signature 335 356 4.6E-17 T 09-03-2017 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 L21SP3_RS06475 dff003a87c8d67381eae85467cadc6ae 626 PRINTS PR00741 Glycosyl hydrolase family 29 signature 129 145 4.6E-17 T 09-03-2017 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 L21SP3_RS06475 dff003a87c8d67381eae85467cadc6ae 626 Gene3D G3DSA:2.60.40.1180 409 473 2.4E-6 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta L21SP3_RS06475 dff003a87c8d67381eae85467cadc6ae 626 Gene3D G3DSA:3.20.20.80 47 385 1.2E-102 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS06475 dff003a87c8d67381eae85467cadc6ae 626 Pfam PF01120 Alpha-L-fucosidase 41 381 8.7E-95 T 09-03-2017 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51 L21SP3_RS06475 dff003a87c8d67381eae85467cadc6ae 626 Pfam PF03422 Carbohydrate binding module (family 6) 510 618 3.8E-6 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 L21SP3_RS06475 dff003a87c8d67381eae85467cadc6ae 626 SUPERFAMILY SSF49785 516 617 3.4E-6 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS06475 dff003a87c8d67381eae85467cadc6ae 626 SMART SM00812 41 429 9.6E-131 T 09-03-2017 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51 L21SP3_RS07450 be25e6b1a9d6ef3ff77a2d28d428abec 218 Gene3D G3DSA:3.40.50.150 5 181 8.2E-29 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS07450 be25e6b1a9d6ef3ff77a2d28d428abec 218 Pfam PF08241 Methyltransferase domain 44 129 3.3E-13 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 L21SP3_RS07450 be25e6b1a9d6ef3ff77a2d28d428abec 218 SUPERFAMILY SSF53335 3 185 2.32E-30 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 SUPERFAMILY SSF55326 594 782 1.26E-52 T 09-03-2017 L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 SUPERFAMILY SSF56042 405 626 1.32E-51 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 191 953 7.4E-198 T 09-03-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 Pfam PF02769 AIR synthase related protein, C-terminal domain 787 930 3.7E-22 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 Pfam PF02769 AIR synthase related protein, C-terminal domain 408 559 1.8E-27 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 Gene3D G3DSA:3.90.650.10 405 561 3.6E-6 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 Gene3D G3DSA:3.90.650.10 788 935 1.7E-5 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 Pfam PF00586 AIR synthase related protein, N-terminal domain 282 397 3.8E-16 T 09-03-2017 IPR016188 PurM-like, N-terminal domain L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 Pfam PF00586 AIR synthase related protein, N-terminal domain 663 764 5.3E-4 T 09-03-2017 IPR016188 PurM-like, N-terminal domain L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 SUPERFAMILY SSF82697 83 147 2.79E-5 T 09-03-2017 L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 5 68 3.4E-5 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 84 147 1.7E-4 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 Gene3D G3DSA:3.30.1330.10 220 399 6.5E-39 T 09-03-2017 IPR016188 PurM-like, N-terminal domain L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 Gene3D G3DSA:3.30.1280.10 83 147 1.4E-7 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 Gene3D G3DSA:3.30.1280.10 5 67 1.0E-7 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 SUPERFAMILY SSF56042 784 952 7.48E-40 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 Gene3D G3DSA:3.30.1330.10 614 778 7.7E-43 T 09-03-2017 IPR016188 PurM-like, N-terminal domain L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 SUPERFAMILY SSF82697 4 67 8.72E-7 T 09-03-2017 L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 SUPERFAMILY SSF55326 195 231 2.48E-49 T 09-03-2017 L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 SUPERFAMILY SSF55326 262 401 2.48E-49 T 09-03-2017 L21SP3_RS05170 3602cf7a4390d0b331920272bc6fcf3f 955 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 156 955 216.558 T 09-03-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 439 3.1E-119 T 09-03-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 443 27.654 T 09-03-2017 IPR026593 Protein translocase subunit SecY L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 Gene3D G3DSA:1.10.3370.10 1 446 1.2E-138 T 09-03-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 Pfam PF00344 SecY translocase 76 426 1.6E-107 T 09-03-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 ProSitePatterns PS00756 Protein secY signature 2. 170 187 - T 09-03-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 151 176 2.3E-85 T 09-03-2017 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 177 200 2.3E-85 T 09-03-2017 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 75 95 2.3E-85 T 09-03-2017 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 275 294 2.3E-85 T 09-03-2017 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 412 430 2.3E-85 T 09-03-2017 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 116 139 2.3E-85 T 09-03-2017 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 2.3E-85 T 09-03-2017 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 321 343 2.3E-85 T 09-03-2017 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 376 394 2.3E-85 T 09-03-2017 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 SUPERFAMILY SSF103491 1 434 3.53E-109 T 09-03-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 L21SP3_RS06115 da8a929d3dbcf0111bb1a968df462539 453 PIRSF PIRSF004557 1 450 1.8E-121 T 09-03-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 L21SP3_RS06450 10cf818e35ef86052675c789bbfb62c6 164 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 116 134 - T 09-03-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS06450 10cf818e35ef86052675c789bbfb62c6 164 Gene3D G3DSA:3.40.30.10 77 163 1.3E-14 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS06450 10cf818e35ef86052675c789bbfb62c6 164 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 16 158 3.1E-52 T 09-03-2017 L21SP3_RS06450 10cf818e35ef86052675c789bbfb62c6 164 SUPERFAMILY SSF52833 9 162 1.23E-50 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS06450 10cf818e35ef86052675c789bbfb62c6 164 PIRSF PIRSF000216 1 164 6.1E-55 T 09-03-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 SMART SM00387 41 185 1.3E-19 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 SMART SM00433 45 826 6.9E-241 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR01159 DNA gyrase subunit B signature 253 271 1.0E-76 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR01159 DNA gyrase subunit B signature 371 385 1.0E-76 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR01159 DNA gyrase subunit B signature 802 818 1.0E-76 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR01159 DNA gyrase subunit B signature 229 251 1.0E-76 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR01159 DNA gyrase subunit B signature 385 405 1.0E-76 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR01159 DNA gyrase subunit B signature 481 490 1.0E-76 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR01159 DNA gyrase subunit B signature 190 205 1.0E-76 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR01159 DNA gyrase subunit B signature 16 26 1.0E-76 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR01159 DNA gyrase subunit B signature 205 218 1.0E-76 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR01159 DNA gyrase subunit B signature 323 339 1.0E-76 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR01159 DNA gyrase subunit B signature 786 798 1.0E-76 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 762 821 1.2E-28 T 09-03-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 SUPERFAMILY SSF56719 405 573 1.23E-80 T 09-03-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 SUPERFAMILY SSF56719 759 826 1.23E-80 T 09-03-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 16 833 5.9E-279 T 09-03-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 13 833 84.524 T 09-03-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 Gene3D G3DSA:3.30.565.10 16 227 7.5E-85 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 44 184 9.9E-20 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 SUPERFAMILY SSF55874 15 227 2.46E-65 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 SUPERFAMILY SSF54211 230 402 1.59E-51 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR00418 DNA topoisomerase II family signature 123 137 2.1E-55 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR00418 DNA topoisomerase II family signature 279 292 2.1E-55 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR00418 DNA topoisomerase II family signature 516 533 2.1E-55 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR00418 DNA topoisomerase II family signature 45 60 2.1E-55 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR00418 DNA topoisomerase II family signature 498 514 2.1E-55 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR00418 DNA topoisomerase II family signature 80 93 2.1E-55 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR00418 DNA topoisomerase II family signature 536 548 2.1E-55 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 PRINTS PR00418 DNA topoisomerase II family signature 431 445 2.1E-55 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 Gene3D G3DSA:3.40.50.670 415 563 9.4E-88 T 09-03-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 Gene3D G3DSA:3.40.50.670 750 815 9.4E-88 T 09-03-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 Gene3D G3DSA:3.30.230.10 229 403 1.5E-64 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 Pfam PF01751 Toprim domain 430 535 2.0E-15 T 09-03-2017 IPR006171 Toprim domain L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 Pfam PF00204 DNA gyrase B 230 401 6.1E-58 T 09-03-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS07760 5e50aa5aae9aa51e776acb2a3a15d5c2 833 ProSitePatterns PS00177 DNA topoisomerase II signature. 433 441 - T 09-03-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS03785 34fc77d55d0947a83cf3a167c789ff80 274 Pfam PF13683 Integrase core domain 179 244 6.5E-21 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS03785 34fc77d55d0947a83cf3a167c789ff80 274 SUPERFAMILY SSF53098 88 248 8.6E-36 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS03785 34fc77d55d0947a83cf3a167c789ff80 274 Pfam PF13276 HTH-like domain 23 78 1.3E-7 T 09-03-2017 IPR025948 HTH-like domain L21SP3_RS03785 34fc77d55d0947a83cf3a167c789ff80 274 Gene3D G3DSA:3.30.420.10 88 244 4.6E-37 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS09620 34fc77d55d0947a83cf3a167c789ff80 274 Pfam PF13683 Integrase core domain 179 244 6.5E-21 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS09620 34fc77d55d0947a83cf3a167c789ff80 274 SUPERFAMILY SSF53098 88 248 8.6E-36 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS09620 34fc77d55d0947a83cf3a167c789ff80 274 Pfam PF13276 HTH-like domain 23 78 1.3E-7 T 09-03-2017 IPR025948 HTH-like domain L21SP3_RS09620 34fc77d55d0947a83cf3a167c789ff80 274 Gene3D G3DSA:3.30.420.10 88 244 4.6E-37 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS11705 34fc77d55d0947a83cf3a167c789ff80 274 Pfam PF13683 Integrase core domain 179 244 6.5E-21 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS11705 34fc77d55d0947a83cf3a167c789ff80 274 SUPERFAMILY SSF53098 88 248 8.6E-36 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS11705 34fc77d55d0947a83cf3a167c789ff80 274 Pfam PF13276 HTH-like domain 23 78 1.3E-7 T 09-03-2017 IPR025948 HTH-like domain L21SP3_RS11705 34fc77d55d0947a83cf3a167c789ff80 274 Gene3D G3DSA:3.30.420.10 88 244 4.6E-37 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS05195 34fc77d55d0947a83cf3a167c789ff80 274 Pfam PF13683 Integrase core domain 179 244 6.5E-21 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS05195 34fc77d55d0947a83cf3a167c789ff80 274 SUPERFAMILY SSF53098 88 248 8.6E-36 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS05195 34fc77d55d0947a83cf3a167c789ff80 274 Pfam PF13276 HTH-like domain 23 78 1.3E-7 T 09-03-2017 IPR025948 HTH-like domain L21SP3_RS05195 34fc77d55d0947a83cf3a167c789ff80 274 Gene3D G3DSA:3.30.420.10 88 244 4.6E-37 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS07525 19b4b596134550e6e5353f0d18545d7c 542 SUPERFAMILY SSF53743 136 396 1.96E-13 T 09-03-2017 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 L21SP3_RS10375 8bbf26b474e8332808a6caae7d1aec27 111 Pfam PF00085 Thioredoxin 18 102 8.5E-10 T 09-03-2017 IPR013766 Thioredoxin domain GO:0045454 L21SP3_RS10375 8bbf26b474e8332808a6caae7d1aec27 111 Gene3D G3DSA:3.40.30.10 12 102 4.9E-18 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS10375 8bbf26b474e8332808a6caae7d1aec27 111 SUPERFAMILY SSF52833 11 106 1.43E-18 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 294 441 4.4E-31 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 SUPERFAMILY SSF51445 283 599 2.46E-64 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 Gene3D G3DSA:2.60.120.260 886 1009 7.0E-10 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 SUPERFAMILY SSF49303 186 286 7.19E-16 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 SUPERFAMILY SSF49785 9 173 2.43E-41 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 Pfam PF16355 Domain of unknown function (DUF4982) 622 684 2.0E-19 T 09-03-2017 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 339 364 - T 09-03-2017 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 Pfam PF16990 Carbohydrate binding module (family 35) 886 1009 4.0E-7 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 399 413 - T 09-03-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 Gene3D G3DSA:3.20.20.80 292 489 3.1E-66 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 Gene3D G3DSA:3.20.20.80 525 601 3.1E-66 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 Gene3D G3DSA:2.60.40.1560 608 701 2.2E-20 T 09-03-2017 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 Pfam PF00703 Glycosyl hydrolases family 2 182 286 1.2E-17 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 21 169 2.9E-23 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 PRINTS PR00132 Glycosyl hydrolase family 2 signature 298 312 1.6E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 PRINTS PR00132 Glycosyl hydrolase family 2 signature 399 414 1.6E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 PRINTS PR00132 Glycosyl hydrolase family 2 signature 329 347 1.6E-11 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 SUPERFAMILY SSF49785 885 1008 1.87E-11 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 Gene3D G3DSA:2.60.120.260 16 162 8.6E-39 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10655 b59872a7b4ccab023051050d86551025 1012 Gene3D G3DSA:2.60.40.320 163 287 9.3E-26 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS06235 7def04f884c6f3c17480a844dc2d312c 712 SUPERFAMILY SSF49899 446 663 5.24E-28 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS06235 7def04f884c6f3c17480a844dc2d312c 712 Gene3D G3DSA:2.60.40.10 355 449 1.1E-16 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS06235 7def04f884c6f3c17480a844dc2d312c 712 Pfam PF07679 Immunoglobulin I-set domain 357 453 1.0E-9 T 09-03-2017 IPR013098 Immunoglobulin I-set L21SP3_RS06235 7def04f884c6f3c17480a844dc2d312c 712 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 521 659 5.6E-20 T 09-03-2017 L21SP3_RS06235 7def04f884c6f3c17480a844dc2d312c 712 Gene3D G3DSA:2.60.120.200 450 662 9.7E-30 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS06235 7def04f884c6f3c17480a844dc2d312c 712 SMART SM00409 361 454 3.4E-8 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS06235 7def04f884c6f3c17480a844dc2d312c 712 SUPERFAMILY SSF48726 355 454 5.13E-15 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS00485 ae23c6a2596b7afcb14e80140e59f296 168 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 23 149 4.6E-34 T 09-03-2017 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 L21SP3_RS00485 ae23c6a2596b7afcb14e80140e59f296 168 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 22 164 1.1E-38 T 09-03-2017 IPR002178 PTS EIIA type-2 domain L21SP3_RS00485 ae23c6a2596b7afcb14e80140e59f296 168 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 68 84 - T 09-03-2017 IPR002178 PTS EIIA type-2 domain L21SP3_RS00485 ae23c6a2596b7afcb14e80140e59f296 168 SUPERFAMILY SSF55804 17 163 3.01E-38 T 09-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 L21SP3_RS00485 ae23c6a2596b7afcb14e80140e59f296 168 Gene3D G3DSA:3.40.930.10 15 167 3.5E-45 T 09-03-2017 IPR002178 PTS EIIA type-2 domain L21SP3_RS00915 43686ea8b9d426ebfb5210e4c0939487 382 SUPERFAMILY SSF55347 126 262 9.48E-57 T 09-03-2017 L21SP3_RS00915 43686ea8b9d426ebfb5210e4c0939487 382 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 144 227 4.4E-38 T 09-03-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 L21SP3_RS00915 43686ea8b9d426ebfb5210e4c0939487 382 PIRSF PIRSF006205 2 382 2.6E-146 T 09-03-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 L21SP3_RS00915 43686ea8b9d426ebfb5210e4c0939487 382 Pfam PF13288 DXP reductoisomerase C-terminal domain 260 375 1.4E-35 T 09-03-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 L21SP3_RS00915 43686ea8b9d426ebfb5210e4c0939487 382 Gene3D G3DSA:3.40.50.720 1 148 8.1E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS00915 43686ea8b9d426ebfb5210e4c0939487 382 SUPERFAMILY SSF51735 2 148 6.57E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS00915 43686ea8b9d426ebfb5210e4c0939487 382 Gene3D G3DSA:1.10.1740.10 302 380 2.0E-23 T 09-03-2017 L21SP3_RS00915 43686ea8b9d426ebfb5210e4c0939487 382 SUPERFAMILY SSF69055 290 380 5.23E-26 T 09-03-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 L21SP3_RS00915 43686ea8b9d426ebfb5210e4c0939487 382 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 130 8.0E-38 T 09-03-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 L21SP3_RS00915 43686ea8b9d426ebfb5210e4c0939487 382 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 5 380 44.819 T 09-03-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 L21SP3_RS00915 43686ea8b9d426ebfb5210e4c0939487 382 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3 377 1.3E-132 T 09-03-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 L21SP3_RS08645 b965c43de44625d857c4f88d41d0cf3d 165 Pfam PF00380 Ribosomal protein S9/S16 44 165 2.2E-43 T 09-03-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS08645 b965c43de44625d857c4f88d41d0cf3d 165 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 35 165 27.695 T 09-03-2017 IPR023035 Ribosomal protein S9, bacterial/plastid L21SP3_RS08645 b965c43de44625d857c4f88d41d0cf3d 165 SUPERFAMILY SSF54211 40 165 2.92E-40 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS08645 b965c43de44625d857c4f88d41d0cf3d 165 Gene3D G3DSA:3.30.230.10 41 165 2.2E-45 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP3_RS07775 9ea5fb00642b40dcc45073c251b19e96 319 PIRSF PIRSF000535 4 299 7.9E-46 T 09-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 L21SP3_RS07775 9ea5fb00642b40dcc45073c251b19e96 319 Pfam PF00294 pfkB family carbohydrate kinase 17 291 1.5E-29 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB L21SP3_RS07775 9ea5fb00642b40dcc45073c251b19e96 319 SUPERFAMILY SSF53613 7 292 2.03E-41 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS07775 9ea5fb00642b40dcc45073c251b19e96 319 Gene3D G3DSA:3.40.1190.20 39 296 5.7E-45 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS07775 9ea5fb00642b40dcc45073c251b19e96 319 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 41 65 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 L21SP3_RS10240 2761fd3408fc4e046a227ff617f764a5 195 Pfam PF13289 SIR2-like domain 34 176 8.5E-15 T 09-03-2017 L21SP3_RS02960 40f0d8ef2d3425efff69e4b5d4c336b0 391 SUPERFAMILY SSF111369 64 304 9.02E-23 T 09-03-2017 L21SP3_RS02960 40f0d8ef2d3425efff69e4b5d4c336b0 391 Gene3D G3DSA:2.40.50.100 186 217 2.4E-11 T 09-03-2017 L21SP3_RS02960 40f0d8ef2d3425efff69e4b5d4c336b0 391 Gene3D G3DSA:2.40.50.100 77 108 2.4E-11 T 09-03-2017 L21SP3_RS02960 40f0d8ef2d3425efff69e4b5d4c336b0 391 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 50 379 4.1E-48 T 09-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 L21SP3_RS02960 40f0d8ef2d3425efff69e4b5d4c336b0 391 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 75 286 5.9E-10 T 09-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain L21SP3_RS01070 902d8031d3b7cfb64bd3801368a9e08e 784 Pfam PF01228 Glycine radical 665 766 4.8E-29 T 09-03-2017 IPR001150 Glycine radical domain GO:0003824|GO:0008152 L21SP3_RS01070 902d8031d3b7cfb64bd3801368a9e08e 784 Pfam PF02901 Pyruvate formate lyase-like 1 648 9.9E-207 T 09-03-2017 IPR004184 Pyruvate formate lyase domain GO:0003824 L21SP3_RS01070 902d8031d3b7cfb64bd3801368a9e08e 784 Gene3D G3DSA:3.20.70.20 1 782 1.3E-234 T 09-03-2017 L21SP3_RS01070 902d8031d3b7cfb64bd3801368a9e08e 784 SUPERFAMILY SSF51998 2 782 2.75E-213 T 09-03-2017 L21SP3_RS07815 b2798cc9274787f7ecba3123b2e0b521 203 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 76 197 2.5E-15 T 09-03-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 L21SP3_RS11645 313474445ff31cd7e5162c363275d2f8 271 Hamap MF_01274 Type III pantothenate kinase [coaX]. 8 265 24.06 T 09-03-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 L21SP3_RS11645 313474445ff31cd7e5162c363275d2f8 271 Gene3D G3DSA:3.30.420.40 106 265 8.4E-41 T 09-03-2017 L21SP3_RS11645 313474445ff31cd7e5162c363275d2f8 271 SUPERFAMILY SSF53067 9 129 1.64E-13 T 09-03-2017 L21SP3_RS11645 313474445ff31cd7e5162c363275d2f8 271 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 10 257 4.0E-43 T 09-03-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 L21SP3_RS11645 313474445ff31cd7e5162c363275d2f8 271 Pfam PF03309 Type III pantothenate kinase 9 216 2.6E-46 T 09-03-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 L21SP3_RS11645 313474445ff31cd7e5162c363275d2f8 271 SUPERFAMILY SSF53067 134 262 8.58E-30 T 09-03-2017 L21SP3_RS06140 4c61fa561f65c009c0e7c271d70d0f29 132 Gene3D G3DSA:3.30.1490.10 76 131 2.5E-24 T 09-03-2017 L21SP3_RS06140 4c61fa561f65c009c0e7c271d70d0f29 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 29.788 T 09-03-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06140 4c61fa561f65c009c0e7c271d70d0f29 132 Gene3D G3DSA:3.30.1370.30 3 68 3.0E-25 T 09-03-2017 L21SP3_RS06140 4c61fa561f65c009c0e7c271d70d0f29 132 SUPERFAMILY SSF56047 3 131 5.63E-43 T 09-03-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06140 4c61fa561f65c009c0e7c271d70d0f29 132 Pfam PF00410 Ribosomal protein S8 5 131 1.4E-45 T 09-03-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 Gene3D G3DSA:2.10.230.10 151 220 2.4E-21 T 09-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 PRINTS PR00625 DnaJ domain signature 25 40 2.3E-32 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 PRINTS PR00625 DnaJ domain signature 7 25 2.3E-32 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 PRINTS PR00625 DnaJ domain signature 42 62 2.3E-32 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 PRINTS PR00625 DnaJ domain signature 62 81 2.3E-32 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 Pfam PF00684 DnaJ central domain 156 218 1.2E-13 T 09-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 380 40.384 T 09-03-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 SMART SM00271 4 62 4.7E-35 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 Pfam PF01556 DnaJ C terminal domain 129 344 5.7E-38 T 09-03-2017 IPR002939 Chaperone DnaJ, C-terminal L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 SUPERFAMILY SSF57938 146 220 1.83E-18 T 09-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 Gene3D G3DSA:1.10.287.110 1 106 5.2E-38 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 Gene3D G3DSA:2.60.260.20 114 150 7.5E-17 T 09-03-2017 L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 Gene3D G3DSA:2.60.260.20 221 265 7.5E-17 T 09-03-2017 L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 SUPERFAMILY SSF49493 123 178 2.22E-16 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 SUPERFAMILY SSF49493 224 277 2.22E-16 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 SUPERFAMILY SSF49493 271 355 9.42E-20 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 SUPERFAMILY SSF46565 1 114 2.09E-38 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 Gene3D G3DSA:2.60.260.20 267 345 1.9E-19 T 09-03-2017 L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 361 7.1E-135 T 09-03-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 L21SP3_RS06895 0ec8fb0ef433e85e19945877fbbfe957 385 Pfam PF00226 DnaJ domain 5 67 4.7E-30 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS00280 3cbd5c17f0e9ba40ede624ff611cdb66 1182 SUPERFAMILY SSF57997 668 804 9.15E-5 T 09-03-2017 L21SP3_RS00280 3cbd5c17f0e9ba40ede624ff611cdb66 1182 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1168 4.9E-44 T 09-03-2017 IPR003395 RecF/RecN/SMC, N-terminal L21SP3_RS00280 3cbd5c17f0e9ba40ede624ff611cdb66 1182 Gene3D G3DSA:3.40.50.300 874 938 3.3E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00280 3cbd5c17f0e9ba40ede624ff611cdb66 1182 Gene3D G3DSA:3.40.50.300 1067 1172 3.3E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00280 3cbd5c17f0e9ba40ede624ff611cdb66 1182 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1176 21.299 T 09-03-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 L21SP3_RS00280 3cbd5c17f0e9ba40ede624ff611cdb66 1182 SMART SM00968 521 629 2.1E-6 T 09-03-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 L21SP3_RS00280 3cbd5c17f0e9ba40ede624ff611cdb66 1182 Gene3D G3DSA:3.40.50.300 1 147 2.1E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00280 3cbd5c17f0e9ba40ede624ff611cdb66 1182 PIRSF PIRSF005719 1 1182 9.0E-258 T 09-03-2017 IPR024704 Structural maintenance of chromosomes protein L21SP3_RS00280 3cbd5c17f0e9ba40ede624ff611cdb66 1182 Pfam PF06470 SMC proteins Flexible Hinge Domain 525 628 6.0E-7 T 09-03-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 L21SP3_RS00280 3cbd5c17f0e9ba40ede624ff611cdb66 1182 SUPERFAMILY SSF75553 480 677 1.44E-18 T 09-03-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 L21SP3_RS00280 3cbd5c17f0e9ba40ede624ff611cdb66 1182 SUPERFAMILY SSF52540 981 1168 4.96E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00280 3cbd5c17f0e9ba40ede624ff611cdb66 1182 SUPERFAMILY SSF52540 1 203 4.96E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00280 3cbd5c17f0e9ba40ede624ff611cdb66 1182 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1173 4.1E-296 T 09-03-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 L21SP3_RS05890 3705a8d8f72a97a31147f8e471993533 583 Gene3D G3DSA:3.30.70.20 536 580 3.4E-11 T 09-03-2017 L21SP3_RS05890 3705a8d8f72a97a31147f8e471993533 583 SUPERFAMILY SSF52518 4 216 4.42E-54 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS05890 3705a8d8f72a97a31147f8e471993533 583 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 367 508 2.6E-23 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 L21SP3_RS05890 3705a8d8f72a97a31147f8e471993533 583 Gene3D G3DSA:3.40.50.970 3 179 2.2E-55 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS05890 3705a8d8f72a97a31147f8e471993533 583 PIRSF PIRSF006439 2 583 3.8E-231 T 09-03-2017 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 L21SP3_RS05890 3705a8d8f72a97a31147f8e471993533 583 SUPERFAMILY SSF52518 338 546 4.91E-29 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS05890 3705a8d8f72a97a31147f8e471993533 583 Pfam PF00037 4Fe-4S binding domain 561 578 9.4E-5 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS05890 3705a8d8f72a97a31147f8e471993533 583 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 14 187 8.0E-11 T 09-03-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 L21SP3_RS05890 3705a8d8f72a97a31147f8e471993533 583 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 3 577 2.3E-219 T 09-03-2017 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 L21SP3_RS05890 3705a8d8f72a97a31147f8e471993533 583 SUPERFAMILY SSF52922 222 280 1.23E-6 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP3_RS05890 3705a8d8f72a97a31147f8e471993533 583 Gene3D G3DSA:3.40.50.970 334 535 2.1E-31 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS04730 313a85c309a2d360f08373ded639dee2 589 SMART SM00567 E-Z type HEAT repeats 183 212 21.0 T 09-03-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 L21SP3_RS04730 313a85c309a2d360f08373ded639dee2 589 SMART SM00567 E-Z type HEAT repeats 486 515 42.0 T 09-03-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 L21SP3_RS04730 313a85c309a2d360f08373ded639dee2 589 Gene3D G3DSA:1.25.10.10 349 572 1.0E-9 T 09-03-2017 IPR011989 Armadillo-like helical L21SP3_RS04730 313a85c309a2d360f08373ded639dee2 589 Gene3D G3DSA:1.25.10.10 137 230 2.0E-9 T 09-03-2017 IPR011989 Armadillo-like helical L21SP3_RS04730 313a85c309a2d360f08373ded639dee2 589 SUPERFAMILY SSF48371 347 585 9.87E-12 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 L21SP3_RS04730 313a85c309a2d360f08373ded639dee2 589 SUPERFAMILY SSF48371 166 209 9.87E-12 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 L21SP3_RS04730 313a85c309a2d360f08373ded639dee2 589 Pfam PF13646 HEAT repeats 141 225 3.1E-7 T 09-03-2017 L21SP3_RS10115 c096e5505828c417de3f21b32cfee476 139 Pfam PF00085 Thioredoxin 42 126 2.4E-13 T 09-03-2017 IPR013766 Thioredoxin domain GO:0045454 L21SP3_RS10115 c096e5505828c417de3f21b32cfee476 139 Gene3D G3DSA:3.40.30.10 28 131 8.6E-23 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS10115 c096e5505828c417de3f21b32cfee476 139 SUPERFAMILY SSF52833 37 131 5.98E-23 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 Gene3D G3DSA:2.40.50.140 616 691 1.1E-21 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 PIRSF PIRSF005499 1 702 1.1E-268 T 09-03-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 692 27.668 T 09-03-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 Pfam PF00575 S1 RNA binding domain 616 689 7.2E-14 T 09-03-2017 IPR003029 S1 domain GO:0003676 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 Gene3D G3DSA:3.30.230.70 313 541 2.0E-79 T 09-03-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 Gene3D G3DSA:3.30.230.70 2 224 5.3E-73 T 09-03-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 690 1.0E-274 T 09-03-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 SUPERFAMILY SSF54791 550 623 6.13E-13 T 09-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 SUPERFAMILY SSF46915 228 324 4.05E-17 T 09-03-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 240 318 8.7E-16 T 09-03-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 SUPERFAMILY SSF50249 605 691 1.66E-18 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 Pfam PF03725 3' exoribonuclease family, domain 2 147 209 2.3E-6 T 09-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 Pfam PF03725 3' exoribonuclease family, domain 2 458 526 2.3E-4 T 09-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 SUPERFAMILY SSF55666 448 547 2.8E-26 T 09-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 SUPERFAMILY SSF55666 144 229 7.71E-21 T 09-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 SUPERFAMILY SSF54211 2 143 1.32E-44 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 Pfam PF00013 KH domain 555 610 4.0E-10 T 09-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 SMART SM00316 618 689 4.2E-20 T 09-03-2017 IPR022967 RNA-binding domain, S1 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 SMART SM00322 550 614 4.8E-11 T 09-03-2017 IPR004087 K Homology domain GO:0003676 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 Gene3D G3DSA:3.30.1370.10 549 615 3.3E-19 T 09-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 Gene3D G3DSA:1.10.10.400 227 312 8.3E-19 T 09-03-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 Pfam PF01138 3' exoribonuclease family, domain 1 322 454 7.0E-21 T 09-03-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 Pfam PF01138 3' exoribonuclease family, domain 1 14 143 5.1E-21 T 09-03-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 L21SP3_RS04240 98de021877195a4047959549b0f40b30 702 SUPERFAMILY SSF54211 296 490 7.59E-47 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS03655 db1e7e5cf1539cfe6b8d45109f2cc7bd 223 SUPERFAMILY SSF56214 108 217 8.89E-6 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 L21SP3_RS03655 db1e7e5cf1539cfe6b8d45109f2cc7bd 223 Gene3D G3DSA:3.90.470.20 22 122 1.8E-4 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 L21SP3_RS07030 fad32e5b426abe69203a28b495b75117 269 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 97 1.8E-17 T 09-03-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal L21SP3_RS07030 fad32e5b426abe69203a28b495b75117 269 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 09-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 L21SP3_RS07030 fad32e5b426abe69203a28b495b75117 269 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 159 266 2.4E-36 T 09-03-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 L21SP3_RS07030 fad32e5b426abe69203a28b495b75117 269 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 266 2.3E-75 T 09-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 L21SP3_RS07030 fad32e5b426abe69203a28b495b75117 269 SUPERFAMILY SSF48179 159 268 9.69E-32 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP3_RS07030 fad32e5b426abe69203a28b495b75117 269 Gene3D G3DSA:3.40.50.720 2 155 9.7E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS07030 fad32e5b426abe69203a28b495b75117 269 SUPERFAMILY SSF51735 3 155 1.89E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS07030 fad32e5b426abe69203a28b495b75117 269 PIRSF PIRSF000193 1 269 4.5E-73 T 09-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 L21SP3_RS07030 fad32e5b426abe69203a28b495b75117 269 Gene3D G3DSA:1.10.3730.10 159 266 8.7E-35 T 09-03-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 L21SP3_RS07030 fad32e5b426abe69203a28b495b75117 269 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 266 25.456 T 09-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 L21SP3_RS09440 f4ee3a3254550c018f87be6364e1be07 411 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 09-03-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 L21SP3_RS09440 f4ee3a3254550c018f87be6364e1be07 411 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 4.6E-125 T 09-03-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 L21SP3_RS09440 f4ee3a3254550c018f87be6364e1be07 411 PIRSF PIRSF000726 53 409 9.3E-116 T 09-03-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 L21SP3_RS09440 f4ee3a3254550c018f87be6364e1be07 411 Pfam PF13840 ACT domain 336 396 6.1E-9 T 09-03-2017 IPR027795 GATS-like ACT domain L21SP3_RS09440 f4ee3a3254550c018f87be6364e1be07 411 Pfam PF00696 Amino acid kinase family 3 229 1.0E-53 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase L21SP3_RS09440 f4ee3a3254550c018f87be6364e1be07 411 Gene3D G3DSA:3.40.1160.10 1 246 5.7E-66 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase L21SP3_RS09440 f4ee3a3254550c018f87be6364e1be07 411 SUPERFAMILY SSF55021 327 404 2.18E-21 T 09-03-2017 L21SP3_RS09440 f4ee3a3254550c018f87be6364e1be07 411 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 401 1.7E-105 T 09-03-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 L21SP3_RS09440 f4ee3a3254550c018f87be6364e1be07 411 SUPERFAMILY SSF53633 3 243 3.53E-68 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase L21SP3_RS09440 f4ee3a3254550c018f87be6364e1be07 411 SUPERFAMILY SSF55021 247 324 2.32E-14 T 09-03-2017 L21SP3_RS09615 3ee9f4d8462f92ae11604bfbcceb5a23 88 Pfam PF01527 Transposase 2 71 1.9E-19 T 09-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 L21SP3_RS09615 3ee9f4d8462f92ae11604bfbcceb5a23 88 SUPERFAMILY SSF46689 1 82 8.6E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS09615 3ee9f4d8462f92ae11604bfbcceb5a23 88 Gene3D G3DSA:1.10.10.60 17 84 1.2E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS11710 3ee9f4d8462f92ae11604bfbcceb5a23 88 Pfam PF01527 Transposase 2 71 1.9E-19 T 09-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 L21SP3_RS11710 3ee9f4d8462f92ae11604bfbcceb5a23 88 SUPERFAMILY SSF46689 1 82 8.6E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS11710 3ee9f4d8462f92ae11604bfbcceb5a23 88 Gene3D G3DSA:1.10.10.60 17 84 1.2E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS05200 3ee9f4d8462f92ae11604bfbcceb5a23 88 Pfam PF01527 Transposase 2 71 1.9E-19 T 09-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 L21SP3_RS05200 3ee9f4d8462f92ae11604bfbcceb5a23 88 SUPERFAMILY SSF46689 1 82 8.6E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS05200 3ee9f4d8462f92ae11604bfbcceb5a23 88 Gene3D G3DSA:1.10.10.60 17 84 1.2E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS03780 3ee9f4d8462f92ae11604bfbcceb5a23 88 Pfam PF01527 Transposase 2 71 1.9E-19 T 09-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 L21SP3_RS03780 3ee9f4d8462f92ae11604bfbcceb5a23 88 SUPERFAMILY SSF46689 1 82 8.6E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS03780 3ee9f4d8462f92ae11604bfbcceb5a23 88 Gene3D G3DSA:1.10.10.60 17 84 1.2E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS05590 f4d08945481f67bac4f16a690119c4bd 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 2 76 2.0E-24 T 09-03-2017 L21SP3_RS05590 f4d08945481f67bac4f16a690119c4bd 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 156 1.2E-58 T 09-03-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 L21SP3_RS05590 f4d08945481f67bac4f16a690119c4bd 163 SUPERFAMILY SSF55021 2 75 3.44E-20 T 09-03-2017 L21SP3_RS05590 f4d08945481f67bac4f16a690119c4bd 163 SUPERFAMILY SSF55021 80 158 9.77E-21 T 09-03-2017 L21SP3_RS05590 f4d08945481f67bac4f16a690119c4bd 163 Gene3D G3DSA:3.30.70.260 2 76 3.8E-30 T 09-03-2017 L21SP3_RS05590 f4d08945481f67bac4f16a690119c4bd 163 Gene3D G3DSA:3.30.70.1150 84 159 5.4E-25 T 09-03-2017 L21SP3_RS05590 f4d08945481f67bac4f16a690119c4bd 163 Pfam PF01842 ACT domain 3 67 9.8E-15 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 L21SP3_RS05590 f4d08945481f67bac4f16a690119c4bd 163 Pfam PF10369 Small subunit of acetolactate synthase 84 156 3.3E-23 T 09-03-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 L21SP3_RS08020 1839fcf19ce9d96f8e0d1939ce21f1cc 326 Pfam PF01795 MraW methylase family 23 324 1.6E-81 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS08020 1839fcf19ce9d96f8e0d1939ce21f1cc 326 PIRSF PIRSF004486 18 326 2.5E-86 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS08020 1839fcf19ce9d96f8e0d1939ce21f1cc 326 SUPERFAMILY SSF81799 133 244 7.72E-23 T 09-03-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS08020 1839fcf19ce9d96f8e0d1939ce21f1cc 326 Gene3D G3DSA:1.10.150.170 132 246 2.0E-27 T 09-03-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS08020 1839fcf19ce9d96f8e0d1939ce21f1cc 326 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 24 325 30.92 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS08020 1839fcf19ce9d96f8e0d1939ce21f1cc 326 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 23 324 1.8E-77 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS08020 1839fcf19ce9d96f8e0d1939ce21f1cc 326 Gene3D G3DSA:3.40.50.150 247 325 1.6E-38 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08020 1839fcf19ce9d96f8e0d1939ce21f1cc 326 Gene3D G3DSA:3.40.50.150 24 129 1.6E-38 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08020 1839fcf19ce9d96f8e0d1939ce21f1cc 326 SUPERFAMILY SSF53335 24 132 2.06E-35 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08020 1839fcf19ce9d96f8e0d1939ce21f1cc 326 SUPERFAMILY SSF53335 244 325 2.06E-35 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS00360 71cbee7fc5cecf921f047c73ee71df8c 648 Pfam PF14509 Glycosyl-hydrolase 97 C-terminal, oligomerisation 558 647 3.5E-19 T 09-03-2017 IPR029483 Glycosyl-hydrolase 97, C-terminal oligomerisation domain L21SP3_RS00360 71cbee7fc5cecf921f047c73ee71df8c 648 Pfam PF10566 Glycoside hydrolase 97 297 555 1.1E-68 T 09-03-2017 IPR019563 Glycosyl-hydrolase 97, catalytic domain L21SP3_RS00360 71cbee7fc5cecf921f047c73ee71df8c 648 Pfam PF14508 Glycosyl-hydrolase 97 N-terminal 26 292 4.1E-55 T 09-03-2017 IPR029486 Glycosyl-hydrolase 97, N-terminal domain L21SP3_RS00360 71cbee7fc5cecf921f047c73ee71df8c 648 Gene3D G3DSA:3.20.20.70 323 442 6.8E-8 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS00360 71cbee7fc5cecf921f047c73ee71df8c 648 SUPERFAMILY SSF51445 316 504 1.36E-21 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS01500 2f7dff44c1198b135d8ed1d709c6d12a 116 Pfam PF00037 4Fe-4S binding domain 3 25 2.8E-8 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS01500 2f7dff44c1198b135d8ed1d709c6d12a 116 Pfam PF00037 4Fe-4S binding domain 33 54 6.4E-8 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS01500 2f7dff44c1198b135d8ed1d709c6d12a 116 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 39 50 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS01500 2f7dff44c1198b135d8ed1d709c6d12a 116 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS01500 2f7dff44c1198b135d8ed1d709c6d12a 116 SUPERFAMILY SSF54862 2 66 4.54E-20 T 09-03-2017 L21SP3_RS01500 2f7dff44c1198b135d8ed1d709c6d12a 116 Gene3D G3DSA:1.20.120.230 66 116 3.0E-4 T 09-03-2017 L21SP3_RS01500 2f7dff44c1198b135d8ed1d709c6d12a 116 Gene3D G3DSA:3.30.70.20 4 62 2.6E-17 T 09-03-2017 L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 SUPERFAMILY SSF51445 889 1057 4.45E-18 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1439 1603 1.0E-13 T 09-03-2017 L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1116 1268 2.8E-28 T 09-03-2017 L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 SUPERFAMILY SSF49899 1397 1603 2.18E-16 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 Gene3D G3DSA:3.20.20.80 919 1057 1.1E-14 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 SUPERFAMILY SSF49899 1078 1275 7.64E-36 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 Gene3D G3DSA:2.60.20.10 743 816 3.5E-5 T 09-03-2017 L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 Gene3D G3DSA:2.60.120.200 1060 1274 3.8E-35 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 Gene3D G3DSA:2.60.120.200 1434 1605 1.4E-18 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 Gene3D G3DSA:2.60.40.10 67 146 1.0E-6 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 SMART SM00560 1132 1266 0.007 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 SMART SM00560 1453 1602 0.0026 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 SUPERFAMILY SSF50998 166 403 6.67E-8 T 09-03-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 SUPERFAMILY SSF50998 440 543 6.67E-8 T 09-03-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily L21SP3_RS03905 df564d3b2bbff0e89b2e1ae6c512a911 1664 Pfam PF11790 Glycosyl hydrolase catalytic core 843 1056 2.0E-37 T 09-03-2017 IPR024655 Uncharacterised protein family, glycosyl hydrolase catalytic domain L21SP3_RS08115 2b1d10ec0065828b0e5cb51f5cdca136 718 SUPERFAMILY SSF50939 203 347 2.98E-7 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS08115 2b1d10ec0065828b0e5cb51f5cdca136 718 SUPERFAMILY SSF49899 576 714 2.9E-6 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS08115 2b1d10ec0065828b0e5cb51f5cdca136 718 Gene3D G3DSA:2.120.10.10 198 333 3.2E-6 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS04865 6fc982b5d62487fea4f9132789738ba6 86 SUPERFAMILY SSF51735 1 72 1.22E-15 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04865 6fc982b5d62487fea4f9132789738ba6 86 Gene3D G3DSA:3.40.50.720 1 73 2.0E-20 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04865 6fc982b5d62487fea4f9132789738ba6 86 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 73 6.9E-13 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 L21SP3_RS11595 c0e52befd9e12eaa189cebafb9fbfcc4 231 Gene3D G3DSA:3.40.50.2300 2 123 1.1E-43 T 09-03-2017 L21SP3_RS11595 c0e52befd9e12eaa189cebafb9fbfcc4 231 SMART SM00448 4 117 1.5E-46 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS11595 c0e52befd9e12eaa189cebafb9fbfcc4 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 229 3.7E-23 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 L21SP3_RS11595 c0e52befd9e12eaa189cebafb9fbfcc4 231 Pfam PF00072 Response regulator receiver domain 6 118 2.2E-28 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS11595 c0e52befd9e12eaa189cebafb9fbfcc4 231 SUPERFAMILY SSF46894 133 230 1.33E-27 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 L21SP3_RS11595 c0e52befd9e12eaa189cebafb9fbfcc4 231 SMART SM00862 156 229 8.9E-25 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 L21SP3_RS11595 c0e52befd9e12eaa189cebafb9fbfcc4 231 SUPERFAMILY SSF52172 2 126 2.28E-43 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS11595 c0e52befd9e12eaa189cebafb9fbfcc4 231 Gene3D G3DSA:1.10.10.10 134 230 7.6E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS11015 9815126238bdd0072c128b78b0df0e14 221 Gene3D G3DSA:1.10.1670.10 131 213 5.9E-22 T 09-03-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 L21SP3_RS11015 9815126238bdd0072c128b78b0df0e14 221 Pfam PF00633 Helix-hairpin-helix motif 116 136 6.8E-6 T 09-03-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 L21SP3_RS11015 9815126238bdd0072c128b78b0df0e14 221 Gene3D G3DSA:1.10.340.30 20 130 1.8E-38 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 L21SP3_RS11015 9815126238bdd0072c128b78b0df0e14 221 SUPERFAMILY SSF48150 1 213 1.51E-60 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 L21SP3_RS11015 9815126238bdd0072c128b78b0df0e14 221 PIRSF PIRSF001435 1 220 1.7E-75 T 09-03-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 L21SP3_RS11015 9815126238bdd0072c128b78b0df0e14 221 SMART SM00478 37 196 3.2E-38 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 L21SP3_RS11015 9815126238bdd0072c128b78b0df0e14 221 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 33 174 2.1E-18 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 L21SP3_RS00480 c511045d0a9d1847fd38de23075817d8 127 Pfam PF00825 Ribonuclease P 6 100 1.9E-22 T 09-03-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 L21SP3_RS00480 c511045d0a9d1847fd38de23075817d8 127 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 15 88 4.0E-10 T 09-03-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 L21SP3_RS00480 c511045d0a9d1847fd38de23075817d8 127 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 6 122 14.57 T 09-03-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 L21SP3_RS00480 c511045d0a9d1847fd38de23075817d8 127 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 55 69 - T 09-03-2017 IPR020539 Ribonuclease P, conserved site GO:0004526 L21SP3_RS00480 c511045d0a9d1847fd38de23075817d8 127 SUPERFAMILY SSF54211 6 94 6.32E-21 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS00480 c511045d0a9d1847fd38de23075817d8 127 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 8 92 1.1E-17 T 09-03-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 L21SP3_RS00480 c511045d0a9d1847fd38de23075817d8 127 Gene3D G3DSA:3.30.230.10 5 94 1.7E-23 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP3_RS01195 ac4199c2c2742a06dfdbc4e42ba99e8b 308 SUPERFAMILY SSF54862 15 152 2.79E-21 T 09-03-2017 L21SP3_RS01195 ac4199c2c2742a06dfdbc4e42ba99e8b 308 Gene3D G3DSA:3.80.30.10 132 302 6.0E-47 T 09-03-2017 L21SP3_RS01195 ac4199c2c2742a06dfdbc4e42ba99e8b 308 SUPERFAMILY SSF102114 99 266 6.28E-18 T 09-03-2017 L21SP3_RS01195 ac4199c2c2742a06dfdbc4e42ba99e8b 308 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 14 299 7.3E-100 T 09-03-2017 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 L21SP3_RS01195 ac4199c2c2742a06dfdbc4e42ba99e8b 308 ProSitePatterns PS01087 Radical activating enzymes signature. 25 46 - T 09-03-2017 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 L21SP3_RS01195 ac4199c2c2742a06dfdbc4e42ba99e8b 308 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 63 74 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS01195 ac4199c2c2742a06dfdbc4e42ba99e8b 308 Gene3D G3DSA:3.30.70.20 59 112 1.8E-14 T 09-03-2017 L21SP3_RS01195 ac4199c2c2742a06dfdbc4e42ba99e8b 308 PIRSF PIRSF000371 4 308 5.6E-95 T 09-03-2017 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 L21SP3_RS01195 ac4199c2c2742a06dfdbc4e42ba99e8b 308 Pfam PF13353 4Fe-4S single cluster domain 24 177 4.5E-13 T 09-03-2017 L21SP3_RS01195 ac4199c2c2742a06dfdbc4e42ba99e8b 308 Pfam PF04055 Radical SAM superfamily 32 238 4.9E-28 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS06940 8fc32246c451697fa49e61d2ed8d38fb 203 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 18 196 5.1E-42 T 09-03-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase L21SP3_RS06940 8fc32246c451697fa49e61d2ed8d38fb 203 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 18 196 6.4E-35 T 09-03-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase L21SP3_RS06940 8fc32246c451697fa49e61d2ed8d38fb 203 Gene3D G3DSA:3.40.50.10420 18 200 3.5E-48 T 09-03-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain L21SP3_RS06940 8fc32246c451697fa49e61d2ed8d38fb 203 PIRSF PIRSF006806 13 199 1.3E-39 T 09-03-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase L21SP3_RS06940 8fc32246c451697fa49e61d2ed8d38fb 203 SUPERFAMILY SSF100950 18 201 1.06E-41 T 09-03-2017 L21SP3_RS03325 f99e3831241fdc8f26c636958121bf4c 374 Gene3D G3DSA:1.50.10.10 55 237 1.0E-21 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS03325 f99e3831241fdc8f26c636958121bf4c 374 Gene3D G3DSA:1.50.10.10 238 342 3.1E-9 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS03325 f99e3831241fdc8f26c636958121bf4c 374 Pfam PF03663 Glycosyl hydrolase family 76 93 282 7.1E-33 T 09-03-2017 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 L21SP3_RS03325 f99e3831241fdc8f26c636958121bf4c 374 SUPERFAMILY SSF48208 61 349 7.14E-35 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS04840 eaf6019edfed4813397b6b8a3374e8c6 342 Gene3D G3DSA:3.90.550.10 15 214 1.3E-57 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS04840 eaf6019edfed4813397b6b8a3374e8c6 342 Pfam PF00535 Glycosyl transferase family 2 20 186 1.1E-34 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 L21SP3_RS04840 eaf6019edfed4813397b6b8a3374e8c6 342 SUPERFAMILY SSF53448 17 241 3.12E-57 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS04245 6f6fbc1e29a12330b8c42f772ee8e119 603 Gene3D G3DSA:2.130.10.10 39 222 1.2E-9 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 L21SP3_RS04245 6f6fbc1e29a12330b8c42f772ee8e119 603 SUPERFAMILY SSF69322 187 318 3.79E-13 T 09-03-2017 L21SP3_RS04245 6f6fbc1e29a12330b8c42f772ee8e119 603 SUPERFAMILY SSF69322 29 144 3.79E-13 T 09-03-2017 L21SP3_RS06800 9b5ff29a42623dc2121a034b1b9beb00 462 SUPERFAMILY SSF53244 317 449 2.29E-29 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS06800 9b5ff29a42623dc2121a034b1b9beb00 462 SUPERFAMILY SSF63418 12 103 7.98E-18 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 L21SP3_RS06800 9b5ff29a42623dc2121a034b1b9beb00 462 Pfam PF01225 Mur ligase family, catalytic domain 24 102 5.1E-10 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 L21SP3_RS06800 9b5ff29a42623dc2121a034b1b9beb00 462 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 395 2.3E-10 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS06800 9b5ff29a42623dc2121a034b1b9beb00 462 Gene3D G3DSA:3.40.1390.10 1 71 2.5E-19 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 L21SP3_RS06800 9b5ff29a42623dc2121a034b1b9beb00 462 SUPERFAMILY SSF53623 106 309 3.01E-40 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS06800 9b5ff29a42623dc2121a034b1b9beb00 462 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 450 29.254 T 09-03-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS06800 9b5ff29a42623dc2121a034b1b9beb00 462 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 30 447 1.3E-113 T 09-03-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 L21SP3_RS06800 9b5ff29a42623dc2121a034b1b9beb00 462 Gene3D G3DSA:3.90.190.20 317 452 1.2E-33 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 L21SP3_RS06800 9b5ff29a42623dc2121a034b1b9beb00 462 Gene3D G3DSA:3.40.1190.10 90 309 8.8E-54 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS06800 9b5ff29a42623dc2121a034b1b9beb00 462 Pfam PF08245 Mur ligase middle domain 112 295 5.2E-37 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 L21SP3_RS10130 da41d50ea0445a360244f68f18201586 505 Pfam PF00884 Sulfatase 45 393 6.1E-61 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS10130 da41d50ea0445a360244f68f18201586 505 Pfam PF16347 Domain of unknown function (DUF4976) 426 498 1.0E-8 T 09-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 L21SP3_RS10130 da41d50ea0445a360244f68f18201586 505 Gene3D G3DSA:3.30.1120.10 410 497 1.7E-16 T 09-03-2017 L21SP3_RS10130 da41d50ea0445a360244f68f18201586 505 Gene3D G3DSA:3.40.720.10 43 409 3.0E-106 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS10130 da41d50ea0445a360244f68f18201586 505 SUPERFAMILY SSF53649 44 496 1.44E-116 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS10130 da41d50ea0445a360244f68f18201586 505 ProSitePatterns PS00523 Sulfatases signature 1. 92 104 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS10130 da41d50ea0445a360244f68f18201586 505 ProSitePatterns PS00149 Sulfatases signature 2. 140 150 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS05795 7c1faf63223f7b294843af3c2dc6f7a8 345 SUPERFAMILY SSF55931 6 256 5.89E-37 T 09-03-2017 L21SP3_RS05795 7c1faf63223f7b294843af3c2dc6f7a8 345 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 14 240 5.5E-31 T 09-03-2017 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 L21SP3_RS05795 7c1faf63223f7b294843af3c2dc6f7a8 345 Gene3D G3DSA:3.30.590.10 7 242 2.6E-36 T 09-03-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 L21SP3_RS08800 0546223b51814f0be65ed8894237e237 117 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 115 2.1E-25 T 09-03-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS08800 0546223b51814f0be65ed8894237e237 117 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 115 3.3E-25 T 09-03-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS08800 0546223b51814f0be65ed8894237e237 117 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 117 22.768 T 09-03-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS08800 0546223b51814f0be65ed8894237e237 117 SUPERFAMILY SSF141091 1 116 2.22E-25 T 09-03-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS09705 0dac3c085625225a09a13d4c52e98fda 327 SUPERFAMILY SSF53649 232 294 6.87E-5 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09705 0dac3c085625225a09a13d4c52e98fda 327 SUPERFAMILY SSF53649 102 155 6.87E-5 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 SMART SM00387 426 539 1.8E-32 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 Gene3D G3DSA:1.10.287.130 309 376 3.1E-18 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 SUPERFAMILY SSF158472 232 282 5.89E-8 T 09-03-2017 L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 PRINTS PR00344 Bacterial sensor protein C-terminal signature 499 517 5.3E-12 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 492 5.3E-12 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 536 5.3E-12 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 478 5.3E-12 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 Gene3D G3DSA:3.30.565.10 388 537 6.6E-42 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 Pfam PF00512 His Kinase A (phospho-acceptor) domain 314 380 2.0E-18 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 SUPERFAMILY SSF47384 298 381 1.2E-21 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 SUPERFAMILY SSF55874 369 540 7.73E-44 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 427 536 1.1E-23 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 SMART SM00388 313 380 1.1E-22 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 Pfam PF00672 HAMP domain 213 281 3.6E-10 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP3_RS10815 36a60a062167a2d4bf2f40cfd1dc371a 554 SMART SM00304 232 284 4.9E-9 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 L21SP3_RS08740 173b3fc7885cad2c1c5ddd5ba663a718 465 Gene3D G3DSA:3.40.720.10 156 344 6.8E-43 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08740 173b3fc7885cad2c1c5ddd5ba663a718 465 Pfam PF16347 Domain of unknown function (DUF4976) 392 441 7.9E-8 T 09-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 L21SP3_RS08740 173b3fc7885cad2c1c5ddd5ba663a718 465 SUPERFAMILY SSF53649 397 442 2.62E-98 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS08740 173b3fc7885cad2c1c5ddd5ba663a718 465 SUPERFAMILY SSF53649 30 360 2.62E-98 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS08740 173b3fc7885cad2c1c5ddd5ba663a718 465 Gene3D G3DSA:3.30.1120.10 345 362 4.9E-19 T 09-03-2017 L21SP3_RS08740 173b3fc7885cad2c1c5ddd5ba663a718 465 Gene3D G3DSA:3.30.1120.10 399 451 4.9E-19 T 09-03-2017 L21SP3_RS08740 173b3fc7885cad2c1c5ddd5ba663a718 465 Gene3D G3DSA:3.40.720.10 31 144 4.9E-32 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08740 173b3fc7885cad2c1c5ddd5ba663a718 465 Pfam PF00884 Sulfatase 32 298 1.2E-40 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS00605 df94eee403b186908d76ebfc39f0fb44 429 Pfam PF07724 AAA domain (Cdc48 subfamily) 112 311 2.9E-44 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP3_RS00605 df94eee403b186908d76ebfc39f0fb44 429 SUPERFAMILY SSF52540 61 398 3.85E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00605 df94eee403b186908d76ebfc39f0fb44 429 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 318 391 4.9E-12 T 09-03-2017 IPR019489 Clp ATPase, C-terminal L21SP3_RS00605 df94eee403b186908d76ebfc39f0fb44 429 SMART SM00382 111 273 1.3E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS00605 df94eee403b186908d76ebfc39f0fb44 429 Gene3D G3DSA:1.10.8.60 317 410 5.9E-30 T 09-03-2017 L21SP3_RS00605 df94eee403b186908d76ebfc39f0fb44 429 SMART SM00994 10 50 1.7E-10 T 09-03-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 L21SP3_RS00605 df94eee403b186908d76ebfc39f0fb44 429 Gene3D G3DSA:3.40.50.300 64 253 1.6E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00605 df94eee403b186908d76ebfc39f0fb44 429 Gene3D G3DSA:3.40.50.300 295 312 1.6E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00605 df94eee403b186908d76ebfc39f0fb44 429 SUPERFAMILY SSF57716 12 47 2.0E-5 T 09-03-2017 L21SP3_RS00605 df94eee403b186908d76ebfc39f0fb44 429 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 7 408 5.8E-177 T 09-03-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 L21SP3_RS00605 df94eee403b186908d76ebfc39f0fb44 429 Pfam PF06689 ClpX C4-type zinc finger 13 49 4.8E-12 T 09-03-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 L21SP3_RS00605 df94eee403b186908d76ebfc39f0fb44 429 SMART SM01086 318 411 5.5E-26 T 09-03-2017 IPR019489 Clp ATPase, C-terminal L21SP3_RS00605 df94eee403b186908d76ebfc39f0fb44 429 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 4 416 47.569 T 09-03-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 L21SP3_RS01950 c1bb36d04cf2ca8b9e90a2d775e70fb4 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 23.283 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS01950 c1bb36d04cf2ca8b9e90a2d775e70fb4 96 PRINTS PR00297 10kDa chaperonin signature 3 18 1.0E-24 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS01950 c1bb36d04cf2ca8b9e90a2d775e70fb4 96 PRINTS PR00297 10kDa chaperonin signature 81 94 1.0E-24 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS01950 c1bb36d04cf2ca8b9e90a2d775e70fb4 96 PRINTS PR00297 10kDa chaperonin signature 60 72 1.0E-24 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS01950 c1bb36d04cf2ca8b9e90a2d775e70fb4 96 PRINTS PR00297 10kDa chaperonin signature 25 46 1.0E-24 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS01950 c1bb36d04cf2ca8b9e90a2d775e70fb4 96 SMART SM00883 2 94 1.9E-41 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS01950 c1bb36d04cf2ca8b9e90a2d775e70fb4 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 8.7E-31 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS01950 c1bb36d04cf2ca8b9e90a2d775e70fb4 96 SUPERFAMILY SSF50129 1 95 8.71E-30 T 09-03-2017 IPR011032 GroES-like L21SP3_RS01950 c1bb36d04cf2ca8b9e90a2d775e70fb4 96 Gene3D G3DSA:2.30.33.40 1 95 8.0E-34 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 184 2.3E-5 T 09-03-2017 L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 3.4E-46 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.4E-46 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.4E-46 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.4E-46 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.4E-46 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 3.4E-46 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 Gene3D G3DSA:3.40.50.720 3 244 3.9E-86 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.1E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.1E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.1E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 SUPERFAMILY SSF51735 4 244 2.62E-84 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 243 2.9E-65 T 09-03-2017 L21SP3_RS01010 329355b462d7366228da280eacaaaf2e 245 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 244 8.1E-94 T 09-03-2017 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 L21SP3_RS08955 3f81379a772edcb44ad1abaaaceb0f58 214 SUPERFAMILY SSF63380 1 88 1.11E-19 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 L21SP3_RS08955 3f81379a772edcb44ad1abaaaceb0f58 214 SUPERFAMILY SSF63380 92 194 7.57E-28 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 L21SP3_RS08955 3f81379a772edcb44ad1abaaaceb0f58 214 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 196 8.4E-57 T 09-03-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS08955 3f81379a772edcb44ad1abaaaceb0f58 214 PIRSF PIRSF000498 1 209 4.4E-63 T 09-03-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS08955 3f81379a772edcb44ad1abaaaceb0f58 214 Pfam PF00677 Lumazine binding domain 99 183 9.7E-20 T 09-03-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS08955 3f81379a772edcb44ad1abaaaceb0f58 214 Pfam PF00677 Lumazine binding domain 3 86 2.2E-16 T 09-03-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS08955 3f81379a772edcb44ad1abaaaceb0f58 214 Gene3D G3DSA:2.40.30.20 6 103 3.5E-25 T 09-03-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 L21SP3_RS08955 3f81379a772edcb44ad1abaaaceb0f58 214 Gene3D G3DSA:2.40.30.20 104 198 5.0E-26 T 09-03-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 L21SP3_RS01005 c98a83d6409958e3ba7a0ccf54fa9149 311 SUPERFAMILY SSF55048 128 195 9.68E-14 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 L21SP3_RS01005 c98a83d6409958e3ba7a0ccf54fa9149 311 SUPERFAMILY SSF52151 189 306 4.97E-72 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 L21SP3_RS01005 c98a83d6409958e3ba7a0ccf54fa9149 311 SUPERFAMILY SSF52151 3 121 4.97E-72 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 L21SP3_RS01005 c98a83d6409958e3ba7a0ccf54fa9149 311 PIRSF PIRSF000446 1 310 1.0E-97 T 09-03-2017 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 L21SP3_RS01005 c98a83d6409958e3ba7a0ccf54fa9149 311 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 301 5.5E-23 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain L21SP3_RS01005 c98a83d6409958e3ba7a0ccf54fa9149 311 Pfam PF00698 Acyl transferase domain 5 287 3.1E-35 T 09-03-2017 IPR014043 Acyl transferase L21SP3_RS01005 c98a83d6409958e3ba7a0ccf54fa9149 311 Gene3D G3DSA:3.40.366.10 196 298 5.5E-71 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 L21SP3_RS01005 c98a83d6409958e3ba7a0ccf54fa9149 311 Gene3D G3DSA:3.40.366.10 2 121 5.5E-71 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 L21SP3_RS01005 c98a83d6409958e3ba7a0ccf54fa9149 311 Gene3D G3DSA:3.30.70.250 126 195 2.3E-20 T 09-03-2017 L21SP3_RS01005 c98a83d6409958e3ba7a0ccf54fa9149 311 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 2 289 1.1E-100 T 09-03-2017 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 L21SP3_RS03870 f6fa2e0dd2aa3adb03f16c4a79128e7d 525 SMART SM00813 327 516 7.4E-76 T 09-03-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 L21SP3_RS03870 f6fa2e0dd2aa3adb03f16c4a79128e7d 525 SUPERFAMILY SSF51445 49 409 3.58E-98 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS03870 f6fa2e0dd2aa3adb03f16c4a79128e7d 525 Gene3D G3DSA:3.20.20.80 200 359 3.0E-7 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS03870 f6fa2e0dd2aa3adb03f16c4a79128e7d 525 SUPERFAMILY SSF51011 390 520 2.13E-24 T 09-03-2017 L21SP3_RS03870 f6fa2e0dd2aa3adb03f16c4a79128e7d 525 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 327 516 4.8E-43 T 09-03-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 L21SP3_RS08095 a8d0aa7f207cb3e220702088eb2d9030 663 SUPERFAMILY SSF49899 127 311 1.58E-9 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS08095 a8d0aa7f207cb3e220702088eb2d9030 663 SUPERFAMILY SSF75005 306 586 1.71E-54 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS08095 a8d0aa7f207cb3e220702088eb2d9030 663 Gene3D G3DSA:2.60.120.200 26 305 5.9E-13 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS08095 a8d0aa7f207cb3e220702088eb2d9030 663 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 126 305 1.5E-8 T 09-03-2017 L21SP3_RS08095 a8d0aa7f207cb3e220702088eb2d9030 663 Pfam PF04616 Glycosyl hydrolases family 43 317 586 4.3E-44 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS08095 a8d0aa7f207cb3e220702088eb2d9030 663 Gene3D G3DSA:2.115.10.20 307 586 1.8E-64 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS07130 bef9b80547f034d8aa823e2434dbe8fa 399 Gene3D G3DSA:2.140.10.10 33 394 6.9E-27 T 09-03-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain L21SP3_RS07130 bef9b80547f034d8aa823e2434dbe8fa 399 Pfam PF13360 PQQ-like domain 229 347 2.6E-12 T 09-03-2017 IPR002372 Pyrrolo-quinoline quinone repeat L21SP3_RS07130 bef9b80547f034d8aa823e2434dbe8fa 399 SUPERFAMILY SSF50998 213 394 1.39E-25 T 09-03-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily L21SP3_RS03775 a979189e957e6096b3ec152645073460 625 SUPERFAMILY SSF49899 44 241 3.48E-34 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03775 a979189e957e6096b3ec152645073460 625 SUPERFAMILY SSF49899 347 580 9.68E-17 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03775 a979189e957e6096b3ec152645073460 625 Gene3D G3DSA:2.60.120.200 39 242 1.7E-35 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03775 a979189e957e6096b3ec152645073460 625 Gene3D G3DSA:2.60.120.200 346 579 5.4E-14 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03775 a979189e957e6096b3ec152645073460 625 SMART SM00560 103 233 1.2E-5 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS03775 a979189e957e6096b3ec152645073460 625 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 97 236 3.5E-27 T 09-03-2017 L21SP3_RS03775 a979189e957e6096b3ec152645073460 625 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 409 573 3.1E-11 T 09-03-2017 L21SP3_RS06410 2f4ab8fc523180672bc04692c374db87 226 Gene3D G3DSA:3.40.50.720 1 141 2.7E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS06410 2f4ab8fc523180672bc04692c374db87 226 Pfam PF02254 TrkA-N domain 4 122 1.0E-18 T 09-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 L21SP3_RS06410 2f4ab8fc523180672bc04692c374db87 226 Pfam PF02080 TrkA-C domain 153 222 9.5E-9 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 L21SP3_RS06410 2f4ab8fc523180672bc04692c374db87 226 SUPERFAMILY SSF51735 2 134 1.27E-23 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS06410 2f4ab8fc523180672bc04692c374db87 226 Gene3D G3DSA:3.30.70.1450 153 224 1.3E-12 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 L21SP3_RS06410 2f4ab8fc523180672bc04692c374db87 226 SUPERFAMILY SSF116726 134 223 5.23E-12 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 L21SP3_RS11540 53422e52340da37899daa538599f2339 209 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 1 202 44.102 T 09-03-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 L21SP3_RS11540 53422e52340da37899daa538599f2339 209 Gene3D G3DSA:3.90.950.10 1 203 5.9E-68 T 09-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like L21SP3_RS11540 53422e52340da37899daa538599f2339 209 SUPERFAMILY SSF52972 1 202 3.92E-60 T 09-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like L21SP3_RS11540 53422e52340da37899daa538599f2339 209 Pfam PF01725 Ham1 family 3 197 1.6E-48 T 09-03-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 L21SP3_RS11540 53422e52340da37899daa538599f2339 209 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 200 1.3E-50 T 09-03-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 L21SP3_RS01530 f2ae8a95421cd33e6ca360b4ff57e6da 285 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 6 284 1.3E-98 T 09-03-2017 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108 L21SP3_RS01530 f2ae8a95421cd33e6ca360b4ff57e6da 285 Gene3D G3DSA:3.20.10.10 123 283 1.3E-50 T 09-03-2017 L21SP3_RS01530 f2ae8a95421cd33e6ca360b4ff57e6da 285 Pfam PF01063 Amino-transferase class IV 31 258 1.9E-55 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 L21SP3_RS01530 f2ae8a95421cd33e6ca360b4ff57e6da 285 SUPERFAMILY SSF56752 3 283 2.22E-91 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 L21SP3_RS01530 f2ae8a95421cd33e6ca360b4ff57e6da 285 Gene3D G3DSA:3.30.470.10 4 118 3.5E-43 T 09-03-2017 L21SP3_RS01530 f2ae8a95421cd33e6ca360b4ff57e6da 285 ProSitePatterns PS00770 Aminotransferases class-IV signature. 184 213 - T 09-03-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 L21SP3_RS08525 83467c25ee5e56399d6ce9308a71bace 211 SUPERFAMILY SSF53254 28 205 1.7E-39 T 09-03-2017 IPR029033 Histidine phosphatase superfamily L21SP3_RS08525 83467c25ee5e56399d6ce9308a71bace 211 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 30 195 4.3E-38 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 L21SP3_RS08525 83467c25ee5e56399d6ce9308a71bace 211 SMART SM00855 29 180 1.5E-12 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 L21SP3_RS08525 83467c25ee5e56399d6ce9308a71bace 211 Gene3D G3DSA:3.40.50.1240 29 205 4.5E-38 T 09-03-2017 IPR029033 Histidine phosphatase superfamily L21SP3_RS09915 15a6d136a94053a4a1974a9e1fac3266 388 SMART SM00342 300 383 2.2E-13 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS09915 15a6d136a94053a4a1974a9e1fac3266 388 Gene3D G3DSA:3.40.50.2300 114 276 5.4E-28 T 09-03-2017 L21SP3_RS09915 15a6d136a94053a4a1974a9e1fac3266 388 Gene3D G3DSA:1.10.10.60 286 337 2.1E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS09915 15a6d136a94053a4a1974a9e1fac3266 388 SUPERFAMILY SSF53822 93 296 1.05E-29 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS09915 15a6d136a94053a4a1974a9e1fac3266 388 Gene3D G3DSA:1.10.10.60 342 386 3.6E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS09915 15a6d136a94053a4a1974a9e1fac3266 388 SUPERFAMILY SSF46689 337 386 9.86E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS09915 15a6d136a94053a4a1974a9e1fac3266 388 Gene3D G3DSA:3.40.50.2300 61 113 2.8E-5 T 09-03-2017 L21SP3_RS09915 15a6d136a94053a4a1974a9e1fac3266 388 Pfam PF12833 Helix-turn-helix domain 307 385 5.2E-18 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS09915 15a6d136a94053a4a1974a9e1fac3266 388 Pfam PF13377 Periplasmic binding protein-like domain 112 276 9.6E-32 T 09-03-2017 L21SP3_RS05510 2eb602efa88c833a7a143376a64cb28a 341 Pfam PF13524 Glycosyl transferases group 1 228 320 7.3E-8 T 09-03-2017 L21SP3_RS05510 2eb602efa88c833a7a143376a64cb28a 341 SUPERFAMILY SSF53756 50 320 2.28E-9 T 09-03-2017 L21SP3_RS00635 f7d765f23b9c012336790ae30e22356d 336 Gene3D G3DSA:3.80.30.10 123 287 3.4E-33 T 09-03-2017 L21SP3_RS00635 f7d765f23b9c012336790ae30e22356d 336 Pfam PF04055 Radical SAM superfamily 81 233 2.5E-19 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS00635 f7d765f23b9c012336790ae30e22356d 336 SUPERFAMILY SSF102114 62 312 1.31E-31 T 09-03-2017 L21SP3_RS00635 f7d765f23b9c012336790ae30e22356d 336 PIRSF PIRSF004869 1 312 6.0E-90 T 09-03-2017 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted L21SP3_RS00635 f7d765f23b9c012336790ae30e22356d 336 SMART SM00729 74 280 0.0058 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP3_RS00635 f7d765f23b9c012336790ae30e22356d 336 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 6 336 5.2E-102 T 09-03-2017 IPR027596 AmmeMemoRadiSam system radical SAM enzyme L21SP3_RS00715 3c6de128277fcd907ee444201bf9c900 186 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 186 24.1 T 09-03-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 L21SP3_RS00715 3c6de128277fcd907ee444201bf9c900 186 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 186 2.8E-58 T 09-03-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 L21SP3_RS00715 3c6de128277fcd907ee444201bf9c900 186 SUPERFAMILY SSF55194 5 185 6.54E-61 T 09-03-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 L21SP3_RS00715 3c6de128277fcd907ee444201bf9c900 186 Pfam PF01765 Ribosome recycling factor 22 184 1.1E-55 T 09-03-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 L21SP3_RS00715 3c6de128277fcd907ee444201bf9c900 186 Gene3D G3DSA:1.10.132.20 67 186 7.2E-36 T 09-03-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 L21SP3_RS06535 152e4b8cd93c70c2d2611160cb225b37 358 Gene3D G3DSA:3.20.20.70 42 179 1.5E-4 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS06535 152e4b8cd93c70c2d2611160cb225b37 358 PIRSF PIRSF004640 1 358 4.2E-117 T 09-03-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 L21SP3_RS06535 152e4b8cd93c70c2d2611160cb225b37 358 Pfam PF04551 GcpE protein 11 353 1.4E-111 T 09-03-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 L21SP3_RS06535 152e4b8cd93c70c2d2611160cb225b37 358 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 6 357 28.578 T 09-03-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 L21SP3_RS06535 152e4b8cd93c70c2d2611160cb225b37 358 SUPERFAMILY SSF51604 39 135 3.88E-5 T 09-03-2017 IPR029065 Enolase C-terminal domain-like L21SP3_RS06535 152e4b8cd93c70c2d2611160cb225b37 358 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 8 352 2.3E-105 T 09-03-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 L21SP3_RS06535 152e4b8cd93c70c2d2611160cb225b37 358 SUPERFAMILY SSF56014 267 350 1.87E-12 T 09-03-2017 L21SP3_RS02265 f54f2ba8b9309556a2a8079e8bce1b7a 797 SMART SM00408 447 527 7.6E-5 T 09-03-2017 IPR003598 Immunoglobulin subtype 2 L21SP3_RS02265 f54f2ba8b9309556a2a8079e8bce1b7a 797 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 601 746 1.4E-20 T 09-03-2017 L21SP3_RS02265 f54f2ba8b9309556a2a8079e8bce1b7a 797 SMART SM00560 602 743 0.0022 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS02265 f54f2ba8b9309556a2a8079e8bce1b7a 797 SUPERFAMILY SSF48726 435 526 2.56E-11 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS02265 f54f2ba8b9309556a2a8079e8bce1b7a 797 SUPERFAMILY SSF49899 539 751 1.49E-30 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS02265 f54f2ba8b9309556a2a8079e8bce1b7a 797 Gene3D G3DSA:2.60.120.200 531 751 2.4E-32 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS02265 f54f2ba8b9309556a2a8079e8bce1b7a 797 Gene3D G3DSA:2.60.120.200 25 292 5.8E-4 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS02265 f54f2ba8b9309556a2a8079e8bce1b7a 797 Pfam PF13927 Immunoglobulin domain 435 524 2.2E-9 T 09-03-2017 L21SP3_RS02265 f54f2ba8b9309556a2a8079e8bce1b7a 797 Gene3D G3DSA:2.60.40.10 434 529 2.7E-11 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS02265 f54f2ba8b9309556a2a8079e8bce1b7a 797 SMART SM00409 441 540 5.3E-6 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS09200 8ad5f658e06bb1d76246761dec912df8 296 Pfam PF01937 Protein of unknown function DUF89 5 271 1.7E-43 T 09-03-2017 IPR002791 Domain of unknown function DUF89 L21SP3_RS09200 8ad5f658e06bb1d76246761dec912df8 296 SUPERFAMILY SSF111321 1 283 1.19E-73 T 09-03-2017 IPR002791 Domain of unknown function DUF89 L21SP3_RS09200 8ad5f658e06bb1d76246761dec912df8 296 PIRSF PIRSF006593 1 286 2.4E-82 T 09-03-2017 IPR014444 Uncharacterised conserved protein UCP006593 L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 ProSitePatterns PS00801 Transketolase signature 1. 37 56 - T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 Gene3D G3DSA:3.40.50.970 300 486 2.9E-63 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 Gene3D G3DSA:3.40.50.920 500 628 7.8E-25 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 SMART SM00861 321 485 7.2E-56 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 ProSitePatterns PS00802 Transketolase signature 2. 428 444 - T 09-03-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 SUPERFAMILY SSF52518 10 200 4.04E-60 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 SUPERFAMILY SSF52518 248 384 4.04E-60 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 SUPERFAMILY SSF52922 500 629 1.23E-21 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 12 287 7.3E-98 T 09-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 14 627 1.1E-198 T 09-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 11 631 38.167 T 09-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 Pfam PF02779 Transketolase, pyrimidine binding domain 321 484 4.3E-33 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 Pfam PF02780 Transketolase, C-terminal domain 503 622 1.3E-21 T 09-03-2017 IPR033248 Transketolase, C-terminal domain L21SP3_RS09850 942c2735fbe1c69222ad5cc06684f7de 641 Gene3D G3DSA:3.40.50.970 15 299 2.6E-28 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS06070 b5ed69bc418c0b9ee65222a6e75a6ec3 137 SUPERFAMILY SSF54197 1 132 1.7E-43 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 L21SP3_RS06070 b5ed69bc418c0b9ee65222a6e75a6ec3 137 Gene3D G3DSA:3.30.428.10 1 133 1.6E-42 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 L21SP3_RS06070 b5ed69bc418c0b9ee65222a6e75a6ec3 137 ProSitePatterns PS00892 HIT domain signature. 85 103 - T 09-03-2017 IPR019808 Histidine triad, conserved site L21SP3_RS06070 b5ed69bc418c0b9ee65222a6e75a6ec3 137 Pfam PF01230 HIT domain 11 106 4.7E-26 T 09-03-2017 IPR001310 Histidine triad (HIT) protein L21SP3_RS06070 b5ed69bc418c0b9ee65222a6e75a6ec3 137 PRINTS PR00332 Histidine triad family signature 25 43 2.8E-18 T 09-03-2017 IPR001310 Histidine triad (HIT) protein L21SP3_RS06070 b5ed69bc418c0b9ee65222a6e75a6ec3 137 PRINTS PR00332 Histidine triad family signature 92 102 2.8E-18 T 09-03-2017 IPR001310 Histidine triad (HIT) protein L21SP3_RS06070 b5ed69bc418c0b9ee65222a6e75a6ec3 137 PRINTS PR00332 Histidine triad family signature 4 20 2.8E-18 T 09-03-2017 IPR001310 Histidine triad (HIT) protein L21SP3_RS00025 9972e36ece1b9436b5c8c5c9945a8411 149 SUPERFAMILY SSF53098 1 145 1.26E-51 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS00025 9972e36ece1b9436b5c8c5c9945a8411 149 Hamap MF_00042 Ribonuclease H [rnhA]. 1 149 31.368 T 09-03-2017 IPR022892 Ribonuclease H GO:0004523 L21SP3_RS00025 9972e36ece1b9436b5c8c5c9945a8411 149 Gene3D G3DSA:3.30.420.10 2 145 5.7E-52 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS00025 9972e36ece1b9436b5c8c5c9945a8411 149 Pfam PF00075 RNase H 3 143 7.5E-43 T 09-03-2017 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 L21SP3_RS04235 076e0969f44b3380962999bf39def78b 88 SMART SM01387 7 87 5.6E-51 T 09-03-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04235 076e0969f44b3380962999bf39def78b 88 SUPERFAMILY SSF47060 1 88 9.71E-36 T 09-03-2017 IPR009068 S15/NS1, RNA-binding L21SP3_RS04235 076e0969f44b3380962999bf39def78b 88 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 2 88 22.424 T 09-03-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS04235 076e0969f44b3380962999bf39def78b 88 Gene3D G3DSA:1.10.287.10 2 88 1.2E-39 T 09-03-2017 IPR009068 S15/NS1, RNA-binding L21SP3_RS04235 076e0969f44b3380962999bf39def78b 88 Pfam PF00312 Ribosomal protein S15 7 87 3.4E-37 T 09-03-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04235 076e0969f44b3380962999bf39def78b 88 ProSitePatterns PS00362 Ribosomal protein S15 signature. 38 68 - T 09-03-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS04235 076e0969f44b3380962999bf39def78b 88 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 88 1.0E-40 T 09-03-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS04235 076e0969f44b3380962999bf39def78b 88 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 9 87 3.0E-27 T 09-03-2017 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 Pfam PF00873 AcrB/AcrD/AcrF family 11 1035 1.1E-161 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 PRINTS PR00702 Acriflavin resistance protein family signature 42 60 2.7E-24 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 2.7E-24 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 2.7E-24 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 2.7E-24 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 2.7E-24 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 SUPERFAMILY SSF82693 268 324 3.4E-7 T 09-03-2017 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 SUPERFAMILY SSF82693 147 181 3.4E-7 T 09-03-2017 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 SUPERFAMILY SSF82866 292 485 1.96E-35 T 09-03-2017 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 SUPERFAMILY SSF82693 44 137 1.48E-19 T 09-03-2017 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 SUPERFAMILY SSF82714 182 266 5.89E-13 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 SUPERFAMILY SSF82866 810 1040 1.96E-49 T 09-03-2017 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 Gene3D G3DSA:3.30.70.1430 44 143 2.7E-21 T 09-03-2017 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 Gene3D G3DSA:3.30.2090.10 740 813 1.5E-8 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 Gene3D G3DSA:1.10.3850.10 818 1036 6.6E-57 T 09-03-2017 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 Gene3D G3DSA:3.30.2090.10 182 268 1.3E-13 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 Gene3D G3DSA:1.20.1640.10 291 492 4.0E-44 T 09-03-2017 L21SP3_RS02955 d3e27c1ded63b2ed0e3a9a362628f9d4 1051 SUPERFAMILY SSF82714 740 813 2.49E-7 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS01040 10db0c28e571517250c466e126605513 266 Pfam PF00218 Indole-3-glycerol phosphate synthase 9 262 5.3E-85 T 09-03-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 L21SP3_RS01040 10db0c28e571517250c466e126605513 266 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 7 264 32.266 T 09-03-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 L21SP3_RS01040 10db0c28e571517250c466e126605513 266 Gene3D G3DSA:3.20.20.70 6 264 1.8E-91 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS01040 10db0c28e571517250c466e126605513 266 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 58 76 - T 09-03-2017 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 L21SP3_RS01040 10db0c28e571517250c466e126605513 266 SUPERFAMILY SSF51366 17 263 1.88E-77 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP3_RS00790 a940ea2de073ae17811d84e4e80f2420 278 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 251 275 7.2E-6 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS00790 a940ea2de073ae17811d84e4e80f2420 278 Pfam PF07589 PEP-CTERM motif 250 272 4.9E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS00335 c5991866a5aa76d4292bdec1f95d1781 856 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 656 807 6.4E-16 T 09-03-2017 L21SP3_RS00335 c5991866a5aa76d4292bdec1f95d1781 856 SMART SM00560 665 805 0.0088 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS00335 c5991866a5aa76d4292bdec1f95d1781 856 SUPERFAMILY SSF49899 598 812 9.37E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00335 c5991866a5aa76d4292bdec1f95d1781 856 Gene3D G3DSA:2.60.120.200 590 808 1.0E-22 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10845 8b638ad9f4dd59ee75ffeba59e175fc0 250 SUPERFAMILY SSF52467 3 246 4.3E-74 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain L21SP3_RS10845 8b638ad9f4dd59ee75ffeba59e175fc0 250 Gene3D G3DSA:3.30.1600.10 35 72 3.5E-26 T 09-03-2017 IPR026591 Sirtuin family, catalytic core small domain L21SP3_RS10845 8b638ad9f4dd59ee75ffeba59e175fc0 250 Gene3D G3DSA:3.30.1600.10 121 167 3.5E-26 T 09-03-2017 IPR026591 Sirtuin family, catalytic core small domain L21SP3_RS10845 8b638ad9f4dd59ee75ffeba59e175fc0 250 Pfam PF02146 Sir2 family 24 198 2.4E-50 T 09-03-2017 IPR003000 Sirtuin family GO:0070403 L21SP3_RS10845 8b638ad9f4dd59ee75ffeba59e175fc0 250 Gene3D G3DSA:3.40.50.1220 4 34 6.8E-43 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain L21SP3_RS10845 8b638ad9f4dd59ee75ffeba59e175fc0 250 Gene3D G3DSA:3.40.50.1220 174 247 6.8E-43 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain L21SP3_RS10845 8b638ad9f4dd59ee75ffeba59e175fc0 250 Gene3D G3DSA:3.40.50.1220 83 120 6.8E-43 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain L21SP3_RS09505 e9b02ceb10a4b8b714dee223e2460fb6 279 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 6 259 1.5E-62 T 09-03-2017 IPR005232 Conserved hypothetical protein CHP00268 L21SP3_RS09505 e9b02ceb10a4b8b714dee223e2460fb6 279 Pfam PF02540 NAD synthase 17 82 1.2E-8 T 09-03-2017 IPR022310 NAD/GMP synthase L21SP3_RS09505 e9b02ceb10a4b8b714dee223e2460fb6 279 PIRSF PIRSF006661 1 276 5.1E-79 T 09-03-2017 IPR005232 Conserved hypothetical protein CHP00268 L21SP3_RS09505 e9b02ceb10a4b8b714dee223e2460fb6 279 SUPERFAMILY SSF52402 14 206 5.73E-30 T 09-03-2017 L21SP3_RS09505 e9b02ceb10a4b8b714dee223e2460fb6 279 Gene3D G3DSA:3.40.50.620 14 171 1.6E-26 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 SUPERFAMILY SSF48452 37 265 8.35E-37 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 Pfam PF14559 Tetratricopeptide repeat 180 236 4.0E-6 T 09-03-2017 L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 Gene3D G3DSA:1.25.40.10 234 310 6.4E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 Gene3D G3DSA:1.25.40.10 30 136 3.3E-24 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 Pfam PF13432 Tetratricopeptide repeat 69 128 8.3E-8 T 09-03-2017 L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 Gene3D G3DSA:1.25.40.10 137 233 3.9E-23 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 Pfam PF13181 Tetratricopeptide repeat 38 60 0.18 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 SMART SM00028 233 266 66.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 SMART SM00028 165 198 27.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 SMART SM00028 131 164 0.12 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 SMART SM00028 63 96 0.016 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 SMART SM00028 97 130 1.4E-4 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 SMART SM00028 29 62 19.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00530 347ee2864816033f7c0e527041f6344f 323 SMART SM00028 199 232 110.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS09195 8268ee1cc953ddf9ca579257a1d584dc 282 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 226 8.9E-29 T 09-03-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain L21SP3_RS09195 8268ee1cc953ddf9ca579257a1d584dc 282 Pfam PF00037 4Fe-4S binding domain 90 112 9.3E-7 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS09195 8268ee1cc953ddf9ca579257a1d584dc 282 Pfam PF00037 4Fe-4S binding domain 60 82 2.9E-6 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS09195 8268ee1cc953ddf9ca579257a1d584dc 282 Gene3D G3DSA:3.30.70.20 54 105 1.5E-16 T 09-03-2017 L21SP3_RS09195 8268ee1cc953ddf9ca579257a1d584dc 282 Gene3D G3DSA:3.40.50.300 2 53 3.6E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09195 8268ee1cc953ddf9ca579257a1d584dc 282 Gene3D G3DSA:3.40.50.300 106 261 3.6E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09195 8268ee1cc953ddf9ca579257a1d584dc 282 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS09195 8268ee1cc953ddf9ca579257a1d584dc 282 SUPERFAMILY SSF52540 1 105 3.41E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09195 8268ee1cc953ddf9ca579257a1d584dc 282 SUPERFAMILY SSF52540 146 253 3.41E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06325 cc99d83ade6072de7a75642783c2be58 407 Pfam PF02464 Competence-damaged protein 254 404 5.3E-54 T 09-03-2017 IPR008136 CinA, C-terminal L21SP3_RS06325 cc99d83ade6072de7a75642783c2be58 407 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 407 128.991 T 09-03-2017 IPR008135 Competence-induced protein CinA L21SP3_RS06325 cc99d83ade6072de7a75642783c2be58 407 Gene3D G3DSA:3.40.980.10 126 169 4.9E-26 T 09-03-2017 IPR001453 MoaB/Mog domain L21SP3_RS06325 cc99d83ade6072de7a75642783c2be58 407 Gene3D G3DSA:3.40.980.10 3 82 4.9E-26 T 09-03-2017 IPR001453 MoaB/Mog domain L21SP3_RS06325 cc99d83ade6072de7a75642783c2be58 407 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 405 1.1E-92 T 09-03-2017 IPR008135 Competence-induced protein CinA L21SP3_RS06325 cc99d83ade6072de7a75642783c2be58 407 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 262 405 4.8E-42 T 09-03-2017 IPR008136 CinA, C-terminal L21SP3_RS06325 cc99d83ade6072de7a75642783c2be58 407 SMART SM00852 5 171 2.6E-26 T 09-03-2017 IPR001453 MoaB/Mog domain L21SP3_RS06325 cc99d83ade6072de7a75642783c2be58 407 PIRSF PIRSF006728 1 407 3.5E-123 T 09-03-2017 IPR008135 Competence-induced protein CinA L21SP3_RS06325 cc99d83ade6072de7a75642783c2be58 407 SUPERFAMILY SSF142433 246 405 3.01E-53 T 09-03-2017 IPR008136 CinA, C-terminal L21SP3_RS06325 cc99d83ade6072de7a75642783c2be58 407 Gene3D G3DSA:3.90.950.20 245 405 1.4E-53 T 09-03-2017 IPR008136 CinA, C-terminal L21SP3_RS06325 cc99d83ade6072de7a75642783c2be58 407 SUPERFAMILY SSF53218 2 199 7.59E-32 T 09-03-2017 IPR001453 MoaB/Mog domain L21SP3_RS06325 cc99d83ade6072de7a75642783c2be58 407 Pfam PF00994 Probable molybdopterin binding domain 5 169 1.4E-29 T 09-03-2017 IPR001453 MoaB/Mog domain L21SP3_RS02715 79147fb0c2f22d2fc028b8277b10bcc3 205 Pfam PF08281 Sigma-70, region 4 142 194 4.9E-16 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS02715 79147fb0c2f22d2fc028b8277b10bcc3 205 Gene3D G3DSA:1.10.10.10 135 200 1.5E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS02715 79147fb0c2f22d2fc028b8277b10bcc3 205 Gene3D G3DSA:1.10.1740.10 15 118 1.1E-28 T 09-03-2017 L21SP3_RS02715 79147fb0c2f22d2fc028b8277b10bcc3 205 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 198 9.0E-33 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS02715 79147fb0c2f22d2fc028b8277b10bcc3 205 SUPERFAMILY SSF88659 133 195 5.98E-16 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS02715 79147fb0c2f22d2fc028b8277b10bcc3 205 Pfam PF04542 Sigma-70 region 2 35 101 1.1E-14 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS02715 79147fb0c2f22d2fc028b8277b10bcc3 205 SUPERFAMILY SSF88946 12 103 1.41E-25 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03725 afbc6bf7eeece2c2c546aed6f266591f 239 Pfam PF02397 Bacterial sugar transferase 45 233 9.3E-60 T 09-03-2017 IPR003362 Bacterial sugar transferase L21SP3_RS05940 8ff0ecf320dc447947af87e20fcbb341 456 Pfam PF03934 Type II secretion system (T2SS), protein K 353 447 3.9E-10 T 09-03-2017 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 L21SP3_RS05940 8ff0ecf320dc447947af87e20fcbb341 456 Gene3D G3DSA:1.10.150.280 332 417 1.1E-6 T 09-03-2017 L21SP3_RS04055 c00c6e1cd81d4d33cc36b68c6cdd1a9a 334 Gene3D G3DSA:3.20.20.210 73 330 1.2E-30 T 09-03-2017 L21SP3_RS04055 c00c6e1cd81d4d33cc36b68c6cdd1a9a 334 SUPERFAMILY SSF51726 1 328 5.58E-25 T 09-03-2017 L21SP3_RS04055 c00c6e1cd81d4d33cc36b68c6cdd1a9a 334 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 75 329 5.1E-18 T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 L21SP3_RS06700 541596bc836aa90c50147a9fae13947f 437 Gene3D G3DSA:3.40.50.300 1 222 3.0E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06700 541596bc836aa90c50147a9fae13947f 437 Gene3D G3DSA:3.40.50.300 263 404 3.0E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06700 541596bc836aa90c50147a9fae13947f 437 SUPERFAMILY SSF52540 289 397 9.3E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06700 541596bc836aa90c50147a9fae13947f 437 SUPERFAMILY SSF52540 46 227 9.3E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06700 541596bc836aa90c50147a9fae13947f 437 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 47 378 4.6E-25 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP3_RS05070 b5458347be921bbd2334621afe946fbb 748 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 11 345 3.1E-43 T 09-03-2017 IPR005883 Type IV pilus assembly protein PilM L21SP3_RS05070 b5458347be921bbd2334621afe946fbb 748 SUPERFAMILY SSF53067 62 165 2.81E-8 T 09-03-2017 L21SP3_RS05070 b5458347be921bbd2334621afe946fbb 748 SUPERFAMILY SSF53067 187 346 7.26E-13 T 09-03-2017 L21SP3_RS05070 b5458347be921bbd2334621afe946fbb 748 Pfam PF11104 Type IV pilus assembly protein PilM; 11 345 1.9E-35 T 09-03-2017 IPR005883 Type IV pilus assembly protein PilM L21SP3_RS05070 b5458347be921bbd2334621afe946fbb 748 Gene3D G3DSA:3.30.420.40 191 309 1.4E-20 T 09-03-2017 L21SP3_RS09585 54ef7d809f480de57764d14dcbf59af3 376 SUPERFAMILY SSF56796 25 349 1.13E-90 T 09-03-2017 L21SP3_RS09585 54ef7d809f480de57764d14dcbf59af3 376 Gene3D G3DSA:1.20.1090.10 180 363 3.8E-54 T 09-03-2017 L21SP3_RS09585 54ef7d809f480de57764d14dcbf59af3 376 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 26 351 2.5E-98 T 09-03-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 L21SP3_RS09585 54ef7d809f480de57764d14dcbf59af3 376 Pfam PF01761 3-dehydroquinate synthase 75 331 2.8E-89 T 09-03-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 L21SP3_RS09585 54ef7d809f480de57764d14dcbf59af3 376 PIRSF PIRSF001455 7 370 3.2E-96 T 09-03-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 L21SP3_RS09585 54ef7d809f480de57764d14dcbf59af3 376 Gene3D G3DSA:3.40.50.1970 21 179 1.3E-48 T 09-03-2017 L21SP3_RS09585 54ef7d809f480de57764d14dcbf59af3 376 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 10 369 34.214 T 09-03-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 L21SP3_RS06375 ed024cb6f8a4632b0e2da966fb321bca 242 SUPERFAMILY SSF53448 8 217 2.33E-45 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS06375 ed024cb6f8a4632b0e2da966fb321bca 242 Gene3D G3DSA:3.90.550.10 8 202 8.1E-36 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS06375 ed024cb6f8a4632b0e2da966fb321bca 242 Pfam PF00535 Glycosyl transferase family 2 12 176 1.6E-30 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 L21SP3_RS03865 b9a1f4c8f70e5ad238f3dae0cbcf98ed 174 Pfam PF07638 ECF sigma factor 94 155 1.6E-4 T 09-03-2017 IPR011517 RNA polymerase sigma-70 ECF-like L21SP3_RS03865 b9a1f4c8f70e5ad238f3dae0cbcf98ed 174 SUPERFAMILY SSF88659 120 166 8.22E-7 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03865 b9a1f4c8f70e5ad238f3dae0cbcf98ed 174 TIGRFAM TIGR02989 Sig-70_gvs1: RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family 9 165 5.7E-46 T 09-03-2017 IPR014331 RNA polymerase sigma-70 ECF-like, Rhodopirellula baltica L21SP3_RS03865 b9a1f4c8f70e5ad238f3dae0cbcf98ed 174 Gene3D G3DSA:1.10.1740.10 8 105 4.9E-23 T 09-03-2017 L21SP3_RS03865 b9a1f4c8f70e5ad238f3dae0cbcf98ed 174 Gene3D G3DSA:1.10.10.10 121 161 6.1E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS03865 b9a1f4c8f70e5ad238f3dae0cbcf98ed 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 157 4.2E-26 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03865 b9a1f4c8f70e5ad238f3dae0cbcf98ed 174 SUPERFAMILY SSF88946 8 96 1.6E-20 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03865 b9a1f4c8f70e5ad238f3dae0cbcf98ed 174 Pfam PF04542 Sigma-70 region 2 14 81 3.7E-15 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS06675 852c929400640afd7ce9428293c64c56 410 Pfam PF16930 Putative porin 97 262 4.5E-34 T 09-03-2017 IPR032638 Putative bacterial porin L21SP3_RS06675 852c929400640afd7ce9428293c64c56 410 Pfam PF16930 Putative porin 313 410 1.2E-13 T 09-03-2017 IPR032638 Putative bacterial porin L21SP3_RS06675 852c929400640afd7ce9428293c64c56 410 SUPERFAMILY SSF56935 78 410 8.93E-9 T 09-03-2017 L21SP3_RS05390 a1949a12cd9383a62d8be3dbdb9a8f1c 555 SUPERFAMILY SSF143975 1 373 3.4E-135 T 09-03-2017 L21SP3_RS05390 a1949a12cd9383a62d8be3dbdb9a8f1c 555 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 09-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 L21SP3_RS05390 a1949a12cd9383a62d8be3dbdb9a8f1c 555 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 462 473 - T 09-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 L21SP3_RS05390 a1949a12cd9383a62d8be3dbdb9a8f1c 555 SUPERFAMILY SSF52016 374 554 8.63E-64 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel L21SP3_RS05390 a1949a12cd9383a62d8be3dbdb9a8f1c 555 Pfam PF00920 Dehydratase family 31 551 1.7E-228 T 09-03-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 L21SP3_RS05390 a1949a12cd9383a62d8be3dbdb9a8f1c 555 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 554 46.879 T 09-03-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 L21SP3_RS05390 a1949a12cd9383a62d8be3dbdb9a8f1c 555 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 554 5.1E-251 T 09-03-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 L21SP3_RS04635 0492656038eb65df924a55633b3fe97b 144 SUPERFAMILY SSF52172 4 133 2.7E-28 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS04635 0492656038eb65df924a55633b3fe97b 144 Pfam PF00072 Response regulator receiver domain 7 127 8.8E-19 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS04635 0492656038eb65df924a55633b3fe97b 144 Gene3D G3DSA:3.40.50.2300 2 133 1.5E-29 T 09-03-2017 L21SP3_RS04635 0492656038eb65df924a55633b3fe97b 144 SMART SM00448 5 127 1.6E-20 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS03245 5f9d52bf96755f71c698fc8903638be2 455 Gene3D G3DSA:1.20.1250.20 220 417 1.2E-18 T 09-03-2017 L21SP3_RS03245 5f9d52bf96755f71c698fc8903638be2 455 Gene3D G3DSA:1.20.1250.20 30 194 2.3E-6 T 09-03-2017 L21SP3_RS03245 5f9d52bf96755f71c698fc8903638be2 455 Pfam PF07690 Major Facilitator Superfamily 61 374 3.2E-16 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 L21SP3_RS03245 5f9d52bf96755f71c698fc8903638be2 455 SUPERFAMILY SSF103473 35 417 2.88E-29 T 09-03-2017 IPR020846 Major facilitator superfamily domain L21SP3_RS03640 5d96b5467a555a3b438c300e5e50e728 251 Pfam PF13633 Prokaryotic N-terminal methylation site 7 33 3.9E-5 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS03640 5d96b5467a555a3b438c300e5e50e728 251 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 2.3E-6 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS03640 5d96b5467a555a3b438c300e5e50e728 251 Gene3D G3DSA:3.30.700.10 10 61 1.8E-5 T 09-03-2017 L21SP3_RS03640 5d96b5467a555a3b438c300e5e50e728 251 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS03640 5d96b5467a555a3b438c300e5e50e728 251 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 198 213 3.4E-4 T 09-03-2017 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP3_RS03640 5d96b5467a555a3b438c300e5e50e728 251 SUPERFAMILY SSF54523 10 107 2.9E-12 T 09-03-2017 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 Pfam PF00890 FAD binding domain 24 396 2.1E-92 T 09-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 SUPERFAMILY SSF51905 360 411 1.8E-64 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 SUPERFAMILY SSF51905 19 259 1.8E-64 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 23 521 6.1E-162 T 09-03-2017 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 25 44 5.1E-9 T 09-03-2017 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 381 5.1E-9 T 09-03-2017 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 SUPERFAMILY SSF56425 242 357 1.39E-38 T 09-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 Gene3D G3DSA:1.20.58.100 437 536 1.3E-26 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 Gene3D G3DSA:3.50.50.60 353 416 5.0E-97 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 Gene3D G3DSA:3.50.50.60 16 247 5.0E-97 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 Pfam PF02910 Fumarate reductase flavoprotein C-term 444 534 1.9E-15 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 SUPERFAMILY SSF46977 439 536 9.55E-28 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 Gene3D G3DSA:3.90.700.10 248 352 6.9E-37 T 09-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 L21SP3_RS10635 f11ec71123d52ef3f18bcf952640d711 539 PIRSF PIRSF000171 13 537 8.7E-39 T 09-03-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 Gene3D G3DSA:2.60.40.1180 544 637 7.6E-28 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 SUPERFAMILY SSF51011 551 636 3.96E-17 T 09-03-2017 L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 Gene3D G3DSA:3.20.20.70 260 543 8.7E-110 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 Pfam PF05345 Putative Ig domain 211 244 5.0E-6 T 09-03-2017 IPR008009 Putative Ig L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 SMART SM00776 16 154 2.5E-35 T 09-03-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 PRINTS PR00740 Glycosyl hydrolase family 27 signature 340 361 8.8E-35 T 09-03-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 PRINTS PR00740 Glycosyl hydrolase family 27 signature 505 526 8.8E-35 T 09-03-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 PRINTS PR00740 Glycosyl hydrolase family 27 signature 297 312 8.8E-35 T 09-03-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 PRINTS PR00740 Glycosyl hydrolase family 27 signature 374 391 8.8E-35 T 09-03-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 PRINTS PR00740 Glycosyl hydrolase family 27 signature 261 280 8.8E-35 T 09-03-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 PRINTS PR00740 Glycosyl hydrolase family 27 signature 409 427 8.8E-35 T 09-03-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 Pfam PF10632 He_PIG associated, NEW1 domain of bacterial glycohydrolase 180 208 8.9E-15 T 09-03-2017 IPR019599 Alpha-galactosidase, NEW1 domain L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 SUPERFAMILY SSF51445 263 550 8.16E-81 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 Pfam PF08305 NPCBM/NEW2 domain 19 152 3.0E-42 T 09-03-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 SUPERFAMILY SSF49785 20 153 1.32E-38 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS11605 38a8b73eefb7e4a9408afacb54fb5a49 638 Pfam PF16499 Alpha galactosidase A 266 595 2.4E-67 T 09-03-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 L21SP3_RS10075 d274713592a62bccb23900c3512c9f44 493 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 13 490 8.7E-120 T 09-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10075 d274713592a62bccb23900c3512c9f44 493 PRINTS PR00045 Sigma-54 factor signature 466 484 8.4E-23 T 09-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10075 d274713592a62bccb23900c3512c9f44 493 PRINTS PR00045 Sigma-54 factor signature 199 216 8.4E-23 T 09-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10075 d274713592a62bccb23900c3512c9f44 493 PRINTS PR00045 Sigma-54 factor signature 406 417 8.4E-23 T 09-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10075 d274713592a62bccb23900c3512c9f44 493 PRINTS PR00045 Sigma-54 factor signature 390 402 8.4E-23 T 09-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10075 d274713592a62bccb23900c3512c9f44 493 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 10 53 7.8E-12 T 09-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10075 d274713592a62bccb23900c3512c9f44 493 Pfam PF04963 Sigma-54 factor, core binding domain 127 316 1.1E-44 T 09-03-2017 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 L21SP3_RS10075 d274713592a62bccb23900c3512c9f44 493 Pfam PF04552 Sigma-54, DNA binding domain 331 491 1.0E-55 T 09-03-2017 IPR007634 RNA polymerase sigma factor 54, DNA-binding L21SP3_RS10075 d274713592a62bccb23900c3512c9f44 493 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 471 478 - T 09-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10075 d274713592a62bccb23900c3512c9f44 493 PIRSF PIRSF000774 1 493 9.8E-133 T 09-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10075 d274713592a62bccb23900c3512c9f44 493 Gene3D G3DSA:1.10.10.10 376 400 1.9E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS10720 77dd2dd737167e4ae94cc72481c0b93e 767 Pfam PF07971 Glycosyl hydrolase family 92 244 744 5.2E-171 T 09-03-2017 IPR012939 Glycosyl hydrolase family 92 L21SP3_RS10720 77dd2dd737167e4ae94cc72481c0b93e 767 Gene3D G3DSA:2.70.98.10 29 328 9.7E-106 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS10720 77dd2dd737167e4ae94cc72481c0b93e 767 SUPERFAMILY SSF48208 271 740 1.13E-36 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS10720 77dd2dd737167e4ae94cc72481c0b93e 767 Gene3D G3DSA:3.30.2080.10 610 755 1.6E-69 T 09-03-2017 L21SP3_RS10720 77dd2dd737167e4ae94cc72481c0b93e 767 Gene3D G3DSA:1.20.1050.60 355 444 1.3E-32 T 09-03-2017 L21SP3_RS10720 77dd2dd737167e4ae94cc72481c0b93e 767 Gene3D G3DSA:1.20.1610.10 451 609 4.7E-63 T 09-03-2017 L21SP3_RS10720 77dd2dd737167e4ae94cc72481c0b93e 767 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 8 749 4.7E-244 T 09-03-2017 IPR005887 Alpha-1,2-mannosidase, putative L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 Pfam PF02867 Ribonucleotide reductase, barrel domain 172 710 6.9E-135 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 81 720 1.2E-174 T 09-03-2017 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 Gene3D G3DSA:3.20.70.20 669 715 9.0E-102 T 09-03-2017 L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 Gene3D G3DSA:3.20.70.20 552 598 9.0E-102 T 09-03-2017 L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 Gene3D G3DSA:3.20.70.20 46 494 9.0E-102 T 09-03-2017 L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 40 123 2.8E-21 T 09-03-2017 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 PRINTS PR01183 Ribonucleotide reductase large chain signature 552 579 1.2E-15 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 PRINTS PR01183 Ribonucleotide reductase large chain signature 446 468 1.2E-15 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 PRINTS PR01183 Ribonucleotide reductase large chain signature 474 497 1.2E-15 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 PRINTS PR01183 Ribonucleotide reductase large chain signature 408 431 1.2E-15 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 PRINTS PR01183 Ribonucleotide reductase large chain signature 374 385 1.2E-15 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 PRINTS PR01183 Ribonucleotide reductase large chain signature 247 266 1.2E-15 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 SUPERFAMILY SSF51998 172 602 3.36E-127 T 09-03-2017 L21SP3_RS04070 4ce903c8a5ecf232603e5d960a66646d 974 SUPERFAMILY SSF51998 636 714 3.36E-127 T 09-03-2017 L21SP3_RS06685 f04c25b34c23cc7b061dc216589958f9 295 Pfam PF01882 Protein of unknown function DUF58 37 122 3.9E-24 T 09-03-2017 IPR002881 Domain of unknown function DUF58 L21SP3_RS06685 f04c25b34c23cc7b061dc216589958f9 295 SUPERFAMILY SSF53300 73 211 9.41E-16 T 09-03-2017 IPR002035 von Willebrand factor, type A L21SP3_RS06685 f04c25b34c23cc7b061dc216589958f9 295 SMART SM00327 76 240 0.0022 T 09-03-2017 IPR002035 von Willebrand factor, type A L21SP3_RS01705 0ebd14d78edda17b5cc8bc1a0eb9717e 434 Pfam PF07977 FabA-like domain 301 423 2.1E-30 T 09-03-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 L21SP3_RS01705 0ebd14d78edda17b5cc8bc1a0eb9717e 434 Gene3D G3DSA:3.30.1700.10 129 275 3.7E-39 T 09-03-2017 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 L21SP3_RS01705 0ebd14d78edda17b5cc8bc1a0eb9717e 434 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 1 276 1.8E-67 T 09-03-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 L21SP3_RS01705 0ebd14d78edda17b5cc8bc1a0eb9717e 434 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 1 278 33.594 T 09-03-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 L21SP3_RS01705 0ebd14d78edda17b5cc8bc1a0eb9717e 434 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 292 428 9.3E-55 T 09-03-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 L21SP3_RS01705 0ebd14d78edda17b5cc8bc1a0eb9717e 434 SUPERFAMILY SSF54211 132 274 3.19E-31 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS01705 0ebd14d78edda17b5cc8bc1a0eb9717e 434 Gene3D G3DSA:3.10.129.10 291 431 3.9E-49 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS01705 0ebd14d78edda17b5cc8bc1a0eb9717e 434 Gene3D G3DSA:3.30.230.20 1 122 3.5E-39 T 09-03-2017 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 L21SP3_RS01705 0ebd14d78edda17b5cc8bc1a0eb9717e 434 SUPERFAMILY SSF54211 1 122 1.74E-34 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS01705 0ebd14d78edda17b5cc8bc1a0eb9717e 434 SUPERFAMILY SSF54637 294 433 4.67E-41 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS01705 0ebd14d78edda17b5cc8bc1a0eb9717e 434 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 3 274 1.6E-86 T 09-03-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 L21SP3_RS01705 0ebd14d78edda17b5cc8bc1a0eb9717e 434 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 292 431 31.866 T 09-03-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 L21SP3_RS10915 decf703613ae2a03ecc7f5e0705e38d1 1048 SUPERFAMILY SSF49899 784 996 1.39E-18 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10915 decf703613ae2a03ecc7f5e0705e38d1 1048 SMART SM00409 699 780 0.0075 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS10915 decf703613ae2a03ecc7f5e0705e38d1 1048 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 838 990 3.3E-13 T 09-03-2017 L21SP3_RS10915 decf703613ae2a03ecc7f5e0705e38d1 1048 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 453 615 3.9E-18 T 09-03-2017 L21SP3_RS10915 decf703613ae2a03ecc7f5e0705e38d1 1048 SUPERFAMILY SSF56300 24 349 1.07E-15 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS10915 decf703613ae2a03ecc7f5e0705e38d1 1048 Gene3D G3DSA:2.60.120.200 403 617 6.0E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10915 decf703613ae2a03ecc7f5e0705e38d1 1048 Gene3D G3DSA:2.60.120.200 777 995 5.4E-16 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10915 decf703613ae2a03ecc7f5e0705e38d1 1048 Gene3D G3DSA:3.60.21.10 67 168 5.8E-18 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS10915 decf703613ae2a03ecc7f5e0705e38d1 1048 Gene3D G3DSA:3.60.21.10 201 339 5.8E-18 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS10915 decf703613ae2a03ecc7f5e0705e38d1 1048 SMART SM00560 471 612 0.0036 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS10915 decf703613ae2a03ecc7f5e0705e38d1 1048 SUPERFAMILY SSF49899 399 619 2.05E-23 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10915 decf703613ae2a03ecc7f5e0705e38d1 1048 Gene3D G3DSA:2.60.40.10 694 776 1.2E-9 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS10915 decf703613ae2a03ecc7f5e0705e38d1 1048 SUPERFAMILY SSF48726 693 775 5.16E-8 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS10430 539f55eb0c1169955343e801b5298990 363 SUPERFAMILY SSF53756 3 360 4.35E-75 T 09-03-2017 L21SP3_RS10430 539f55eb0c1169955343e801b5298990 363 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 185 351 3.5E-27 T 09-03-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 L21SP3_RS10430 539f55eb0c1169955343e801b5298990 363 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 360 25.28 T 09-03-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 L21SP3_RS10430 539f55eb0c1169955343e801b5298990 363 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 138 1.2E-22 T 09-03-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 L21SP3_RS10430 539f55eb0c1169955343e801b5298990 363 Gene3D G3DSA:3.40.50.2000 187 345 3.6E-23 T 09-03-2017 L21SP3_RS10430 539f55eb0c1169955343e801b5298990 363 Gene3D G3DSA:3.40.50.2000 1 186 4.5E-41 T 09-03-2017 L21SP3_RS01615 b5ae99d802007b81ed09dfabcae6975e 230 Gene3D G3DSA:2.60.120.200 26 230 2.5E-30 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS01615 b5ae99d802007b81ed09dfabcae6975e 230 SUPERFAMILY SSF49899 26 230 2.98E-33 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS01615 b5ae99d802007b81ed09dfabcae6975e 230 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 77 230 1.1E-24 T 09-03-2017 L21SP3_RS10840 107152489f5402db56965bcf11d6ff94 607 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 272 286 - T 09-03-2017 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 L21SP3_RS10840 107152489f5402db56965bcf11d6ff94 607 Pfam PF13932 GidA associated domain 400 596 9.2E-65 T 09-03-2017 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 L21SP3_RS10840 107152489f5402db56965bcf11d6ff94 607 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 602 7.9E-244 T 09-03-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 L21SP3_RS10840 107152489f5402db56965bcf11d6ff94 607 SUPERFAMILY SSF51905 5 66 6.02E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10840 107152489f5402db56965bcf11d6ff94 607 SUPERFAMILY SSF51905 97 259 6.02E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10840 107152489f5402db56965bcf11d6ff94 607 SMART SM01228 527 598 2.5E-34 T 09-03-2017 L21SP3_RS10840 107152489f5402db56965bcf11d6ff94 607 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 605 39.649 T 09-03-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 L21SP3_RS10840 107152489f5402db56965bcf11d6ff94 607 Gene3D G3DSA:3.50.50.60 4 173 3.1E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10840 107152489f5402db56965bcf11d6ff94 607 Pfam PF01134 Glucose inhibited division protein A 8 398 3.7E-155 T 09-03-2017 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 L21SP3_RS00435 d451c9074f42bc4f9c60f678a00ef6b9 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 151 9.6E-56 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS00435 d451c9074f42bc4f9c60f678a00ef6b9 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 150 5.5E-52 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS00435 d451c9074f42bc4f9c60f678a00ef6b9 154 SUPERFAMILY SSF52121 5 154 1.03E-58 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS00435 d451c9074f42bc4f9c60f678a00ef6b9 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 9 154 29.436 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS00435 d451c9074f42bc4f9c60f678a00ef6b9 154 Gene3D G3DSA:3.40.50.960 3 153 3.8E-64 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 Gene3D G3DSA:2.40.10.10 150 264 1.2E-37 T 09-03-2017 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 SUPERFAMILY SSF50156 383 462 2.76E-12 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 Gene3D G3DSA:2.30.42.10 386 470 2.0E-13 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 Gene3D G3DSA:2.30.42.10 265 366 1.2E-22 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 PRINTS PR00834 HtrA/DegQ protease family signature 194 211 1.2E-31 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 PRINTS PR00834 HtrA/DegQ protease family signature 92 104 1.2E-31 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 PRINTS PR00834 HtrA/DegQ protease family signature 216 233 1.2E-31 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 PRINTS PR00834 HtrA/DegQ protease family signature 113 133 1.2E-31 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 PRINTS PR00834 HtrA/DegQ protease family signature 155 179 1.2E-31 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 PRINTS PR00834 HtrA/DegQ protease family signature 308 320 1.2E-31 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 Pfam PF13180 PDZ domain 387 469 6.8E-7 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 Pfam PF13180 PDZ domain 262 359 6.9E-19 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 SUPERFAMILY SSF50494 1 46 4.19E-55 T 09-03-2017 IPR009003 Peptidase S1, PA clan L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 SUPERFAMILY SSF50494 79 271 4.19E-55 T 09-03-2017 IPR009003 Peptidase S1, PA clan L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 Pfam PF13365 Trypsin-like peptidase domain 82 223 1.2E-27 T 09-03-2017 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 SMART SM00228 262 350 3.1E-11 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 SMART SM00228 385 465 6.0E-7 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 SUPERFAMILY SSF50156 244 358 2.37E-19 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS03630 d924eef292bd83a8a7a3650bba0638da 474 Gene3D G3DSA:2.40.10.10 24 149 1.0E-25 T 09-03-2017 L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 202 446 2.0E-86 T 09-03-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 57 185 4.0E-51 T 09-03-2017 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 SMART SM00839 204 446 2.0E-93 T 09-03-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 Gene3D G3DSA:1.10.285.10 373 447 2.7E-28 T 09-03-2017 L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 Gene3D G3DSA:1.10.285.10 7 67 2.3E-25 T 09-03-2017 L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 Gene3D G3DSA:3.40.192.10 68 188 6.8E-62 T 09-03-2017 L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 SUPERFAMILY SSF51735 202 447 3.76E-76 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 PIRSF PIRSF000185 22 448 6.2E-119 T 09-03-2017 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 Gene3D G3DSA:3.40.50.720 209 372 3.0E-64 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 SUPERFAMILY SSF53223 6 196 7.04E-75 T 09-03-2017 L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 122 135 - T 09-03-2017 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 114 128 1.5E-31 T 09-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 372 383 1.5E-31 T 09-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 193 215 1.5E-31 T 09-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 L21SP3_RS07965 40ea12cf3a95e37b421f9469ff01e7f7 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 235 255 1.5E-31 T 09-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 L21SP3_RS02070 05aaf2b601439ae5b63a2a086fd95fa4 214 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 100 179 4.4E-19 T 09-03-2017 IPR020057 Ribosomal protein L25, beta domain L21SP3_RS02070 05aaf2b601439ae5b63a2a086fd95fa4 214 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 5 181 24.343 T 09-03-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 L21SP3_RS02070 05aaf2b601439ae5b63a2a086fd95fa4 214 Pfam PF01386 Ribosomal L25p family 7 90 3.5E-22 T 09-03-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 L21SP3_RS02070 05aaf2b601439ae5b63a2a086fd95fa4 214 Gene3D G3DSA:2.170.120.20 95 187 1.9E-21 T 09-03-2017 IPR020057 Ribosomal protein L25, beta domain L21SP3_RS02070 05aaf2b601439ae5b63a2a086fd95fa4 214 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 7 93 1.0E-11 T 09-03-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 L21SP3_RS02070 05aaf2b601439ae5b63a2a086fd95fa4 214 Gene3D G3DSA:2.40.240.10 4 93 8.8E-25 T 09-03-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 L21SP3_RS02070 05aaf2b601439ae5b63a2a086fd95fa4 214 SUPERFAMILY SSF50715 4 187 1.52E-47 T 09-03-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 L21SP3_RS02070 05aaf2b601439ae5b63a2a086fd95fa4 214 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 7 176 9.4E-42 T 09-03-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 L21SP3_RS06590 a5c5a0d6bac60a776683b7c7a67b180e 722 Gene3D G3DSA:2.60.40.10 361 461 2.9E-12 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS06590 a5c5a0d6bac60a776683b7c7a67b180e 722 Pfam PF13927 Immunoglobulin domain 361 445 3.9E-9 T 09-03-2017 L21SP3_RS06590 a5c5a0d6bac60a776683b7c7a67b180e 722 Gene3D G3DSA:2.60.120.200 462 673 2.8E-23 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS06590 a5c5a0d6bac60a776683b7c7a67b180e 722 SUPERFAMILY SSF48726 361 460 7.84E-12 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS06590 a5c5a0d6bac60a776683b7c7a67b180e 722 SMART SM00409 367 460 5.8E-5 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS06590 a5c5a0d6bac60a776683b7c7a67b180e 722 SMART SM00560 528 667 0.0024 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS06590 a5c5a0d6bac60a776683b7c7a67b180e 722 SUPERFAMILY SSF49899 459 674 1.58E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS06590 a5c5a0d6bac60a776683b7c7a67b180e 722 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 524 670 2.9E-18 T 09-03-2017 L21SP3_RS08555 ada3cfd2adef9b4edfd7f4babdc40812 505 Gene3D G3DSA:3.40.50.300 10 242 5.5E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08555 ada3cfd2adef9b4edfd7f4babdc40812 505 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 262 451 5.6E-49 T 09-03-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 L21SP3_RS08555 ada3cfd2adef9b4edfd7f4babdc40812 505 SUPERFAMILY SSF52540 10 245 5.82E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08555 ada3cfd2adef9b4edfd7f4babdc40812 505 Gene3D G3DSA:3.40.50.880 260 462 4.3E-26 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS08555 ada3cfd2adef9b4edfd7f4babdc40812 505 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 11 231 3.7E-31 T 09-03-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain L21SP3_RS08555 ada3cfd2adef9b4edfd7f4babdc40812 505 SUPERFAMILY SSF52317 263 461 4.44E-33 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS08555 ada3cfd2adef9b4edfd7f4babdc40812 505 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 505 160.056 T 09-03-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 L21SP3_RS08555 ada3cfd2adef9b4edfd7f4babdc40812 505 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 12 500 6.9E-140 T 09-03-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 L21SP3_RS00290 b8364a42510dbd1724e9c8b01c123378 406 Gene3D G3DSA:3.30.830.10 229 392 1.4E-23 T 09-03-2017 IPR011237 Peptidase M16 domain GO:0046872 L21SP3_RS00290 b8364a42510dbd1724e9c8b01c123378 406 SUPERFAMILY SSF63411 4 204 3.48E-48 T 09-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 L21SP3_RS00290 b8364a42510dbd1724e9c8b01c123378 406 Pfam PF00675 Insulinase (Peptidase family M16) 17 159 4.0E-32 T 09-03-2017 IPR011765 Peptidase M16, N-terminal L21SP3_RS00290 b8364a42510dbd1724e9c8b01c123378 406 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 34 57 - T 09-03-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 L21SP3_RS00290 b8364a42510dbd1724e9c8b01c123378 406 SUPERFAMILY SSF63411 228 399 7.81E-28 T 09-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 L21SP3_RS00290 b8364a42510dbd1724e9c8b01c123378 406 Gene3D G3DSA:3.30.830.10 4 210 1.9E-48 T 09-03-2017 IPR011237 Peptidase M16 domain GO:0046872 L21SP3_RS00290 b8364a42510dbd1724e9c8b01c123378 406 Pfam PF05193 Peptidase M16 inactive domain 165 337 5.3E-28 T 09-03-2017 IPR007863 Peptidase M16, C-terminal L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 SMART SM01005 251 379 8.6E-48 T 09-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 Gene3D G3DSA:2.40.37.10 229 379 1.2E-49 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 TIGRFAM TIGR00492 alr: alanine racemase 13 379 1.9E-94 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 Hamap MF_01201 Alanine racemase. 9 379 28.972 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 Pfam PF01168 Alanine racemase, N-terminal domain 16 236 1.1E-57 T 09-03-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 40 50 - T 09-03-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 Gene3D G3DSA:3.20.20.10 20 228 1.6E-62 T 09-03-2017 IPR029066 PLP-binding barrel L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 PRINTS PR00992 Alanine racemase signature 211 238 1.1E-47 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 PRINTS PR00992 Alanine racemase signature 267 282 1.1E-47 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 PRINTS PR00992 Alanine racemase signature 284 299 1.1E-47 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 PRINTS PR00992 Alanine racemase signature 305 322 1.1E-47 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 PRINTS PR00992 Alanine racemase signature 35 51 1.1E-47 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 PRINTS PR00992 Alanine racemase signature 361 374 1.1E-47 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 PRINTS PR00992 Alanine racemase signature 134 146 1.1E-47 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 PRINTS PR00992 Alanine racemase signature 168 179 1.1E-47 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 SUPERFAMILY SSF51419 16 252 6.05E-58 T 09-03-2017 IPR029066 PLP-binding barrel L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 SUPERFAMILY SSF50621 244 378 1.43E-41 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 L21SP3_RS06380 e5c6db7ddb4d950079327f5991247f1d 379 Pfam PF00842 Alanine racemase, C-terminal domain 251 377 2.0E-32 T 09-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS07175 8b8dd22c8d41dd0dd1834ec9587c13dd 78 SUPERFAMILY SSF50037 3 73 7.1E-17 T 09-03-2017 IPR008988 Transcriptional repressor, C-terminal L21SP3_RS07175 8b8dd22c8d41dd0dd1834ec9587c13dd 78 SMART SM00899 1 73 4.8E-17 T 09-03-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 L21SP3_RS07175 8b8dd22c8d41dd0dd1834ec9587c13dd 78 Pfam PF04023 FeoA domain 1 72 1.2E-15 T 09-03-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 L21SP3_RS07880 cb1e12988b5de1d97d0436ec17f12c9f 482 Pfam PF03237 Terminase-like family 76 471 2.9E-11 T 09-03-2017 IPR004921 Terminase, large subunit L21SP3_RS06460 d8fc5860075b6b5e4428ec413f60a9ef 581 Gene3D G3DSA:3.30.450.20 411 516 8.2E-6 T 09-03-2017 L21SP3_RS06460 d8fc5860075b6b5e4428ec413f60a9ef 581 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS06460 d8fc5860075b6b5e4428ec413f60a9ef 581 Pfam PF00037 4Fe-4S binding domain 38 57 1.4E-5 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS06460 d8fc5860075b6b5e4428ec413f60a9ef 581 Gene3D G3DSA:3.30.70.20 8 45 6.9E-8 T 09-03-2017 L21SP3_RS06460 d8fc5860075b6b5e4428ec413f60a9ef 581 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS06460 d8fc5860075b6b5e4428ec413f60a9ef 581 SUPERFAMILY SSF55785 413 510 3.05E-5 T 09-03-2017 IPR000014 PAS domain L21SP3_RS06460 d8fc5860075b6b5e4428ec413f60a9ef 581 SUPERFAMILY SSF54862 7 76 6.7E-15 T 09-03-2017 L21SP3_RS06460 d8fc5860075b6b5e4428ec413f60a9ef 581 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 76 305 8.6E-40 T 09-03-2017 IPR004108 Iron hydrogenase, large subunit, C-terminal L21SP3_RS06460 d8fc5860075b6b5e4428ec413f60a9ef 581 Pfam PF04060 Putative Fe-S cluster 374 402 3.3E-9 T 09-03-2017 IPR007202 4Fe-4S domain GO:0051536 L21SP3_RS06460 d8fc5860075b6b5e4428ec413f60a9ef 581 SUPERFAMILY SSF53920 43 362 4.71E-50 T 09-03-2017 IPR009016 Iron hydrogenase L21SP3_RS06460 d8fc5860075b6b5e4428ec413f60a9ef 581 Gene3D G3DSA:3.40.50.1780 139 251 1.2E-24 T 09-03-2017 L21SP3_RS06460 d8fc5860075b6b5e4428ec413f60a9ef 581 Gene3D G3DSA:3.40.50.1780 46 100 1.2E-24 T 09-03-2017 L21SP3_RS09565 be780df89cb6536f94b29a089bc6ee37 1158 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 299 720 1.5E-150 T 09-03-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS09565 be780df89cb6536f94b29a089bc6ee37 1158 SMART SM00481 7 74 3.7E-26 T 09-03-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 L21SP3_RS09565 be780df89cb6536f94b29a089bc6ee37 1158 Gene3D G3DSA:2.40.50.140 981 1068 1.2E-5 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS09565 be780df89cb6536f94b29a089bc6ee37 1158 Gene3D G3DSA:1.10.150.280 829 877 1.5E-4 T 09-03-2017 L21SP3_RS09565 be780df89cb6536f94b29a089bc6ee37 1158 Pfam PF01336 OB-fold nucleic acid binding domain 992 1068 7.7E-7 T 09-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 L21SP3_RS09565 be780df89cb6536f94b29a089bc6ee37 1158 Gene3D G3DSA:3.20.20.140 7 265 2.6E-48 T 09-03-2017 L21SP3_RS09565 be780df89cb6536f94b29a089bc6ee37 1158 SUPERFAMILY SSF89550 8 271 4.51E-37 T 09-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 L21SP3_RS09565 be780df89cb6536f94b29a089bc6ee37 1158 Pfam PF02811 PHP domain 8 180 2.1E-51 T 09-03-2017 IPR004013 PHP domain GO:0003824 L21SP3_RS09565 be780df89cb6536f94b29a089bc6ee37 1158 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1031 0.0 T 09-03-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS09565 be780df89cb6536f94b29a089bc6ee37 1158 Pfam PF14579 Helix-hairpin-helix motif 793 891 1.3E-26 T 09-03-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS01155 4c5e8359eff22a52b302d2f2aa355757 427 Gene3D G3DSA:3.90.1150.10 289 424 2.1E-44 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS01155 4c5e8359eff22a52b302d2f2aa355757 427 PIRSF PIRSF001434 1 426 8.4E-120 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 L21SP3_RS01155 4c5e8359eff22a52b302d2f2aa355757 427 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 6 423 6.4E-185 T 09-03-2017 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 L21SP3_RS01155 4c5e8359eff22a52b302d2f2aa355757 427 SUPERFAMILY SSF53383 5 423 5.36E-115 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS01155 4c5e8359eff22a52b302d2f2aa355757 427 Gene3D G3DSA:3.40.640.10 6 286 2.4E-111 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS01155 4c5e8359eff22a52b302d2f2aa355757 427 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 423 2.9E-131 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 L21SP3_RS07780 611cc47fce25c6339a5d310e29c2b3cc 272 SUPERFAMILY SSF81901 87 249 6.54E-5 T 09-03-2017 L21SP3_RS07780 611cc47fce25c6339a5d310e29c2b3cc 272 Gene3D G3DSA:1.25.40.10 82 246 1.1E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS06725 0bd0abfb12071b1ae3778d4f551e3a79 180 Gene3D G3DSA:3.30.310.70 49 163 1.5E-19 T 09-03-2017 IPR005180 Domain of unknown function DUF302 L21SP3_RS06725 0bd0abfb12071b1ae3778d4f551e3a79 180 Pfam PF03625 Domain of unknown function DUF302 85 147 7.8E-13 T 09-03-2017 IPR005180 Domain of unknown function DUF302 L21SP3_RS06725 0bd0abfb12071b1ae3778d4f551e3a79 180 SUPERFAMILY SSF103247 50 176 4.58E-21 T 09-03-2017 IPR005180 Domain of unknown function DUF302 L21SP3_RS03770 8cbdbb7b5479c76f4368e8e9859f7f20 574 Pfam PF08305 NPCBM/NEW2 domain 421 558 5.5E-5 T 09-03-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module L21SP3_RS03770 8cbdbb7b5479c76f4368e8e9859f7f20 574 Pfam PF04773 FecR protein 172 260 5.4E-6 T 09-03-2017 IPR006860 FecR protein L21SP3_RS08985 2dae29ff7c50c65ad7a84c2e28cc57d7 253 Pfam PF00899 ThiF family 16 251 1.7E-31 T 09-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 L21SP3_RS08985 2dae29ff7c50c65ad7a84c2e28cc57d7 253 Gene3D G3DSA:3.40.50.720 8 252 6.1E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS08985 2dae29ff7c50c65ad7a84c2e28cc57d7 253 SUPERFAMILY SSF69572 9 252 1.1E-53 T 09-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 Gene3D G3DSA:3.30.70.20 566 616 1.9E-15 T 09-03-2017 L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 181 352 4.5E-49 T 09-03-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 463 547 9.3E-35 T 09-03-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 SUPERFAMILY SSF140490 459 560 9.81E-40 T 09-03-2017 L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 SUPERFAMILY SSF52833 17 111 6.82E-16 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 SUPERFAMILY SSF142019 133 373 2.35E-91 T 09-03-2017 L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 Pfam PF12838 4Fe-4S dicluster domain 570 614 1.3E-9 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 SUPERFAMILY SSF54862 567 616 2.04E-16 T 09-03-2017 L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 Pfam PF10531 SLBB domain 376 425 2.0E-7 T 09-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 570 581 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 SUPERFAMILY SSF142984 374 457 2.09E-25 T 09-03-2017 L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 SMART SM00928 462 507 5.4E-28 T 09-03-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 Gene3D G3DSA:3.40.30.10 17 113 2.0E-17 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS01550 60c844085323bedd0a7b5efb4265f7f7 618 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 475 486 - T 09-03-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS08615 b286fa05fc6bb0077eefa8415786fb50 196 ProSitePatterns PS00018 EF-hand calcium-binding domain. 137 149 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS08615 b286fa05fc6bb0077eefa8415786fb50 196 SUPERFAMILY SSF63446 133 192 9.81E-7 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS08615 b286fa05fc6bb0077eefa8415786fb50 196 Gene3D G3DSA:1.10.1330.10 131 194 1.6E-6 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS06365 f0e6c284f5e433b3f7ef6a7942e5a835 395 SUPERFAMILY SSF53383 1 393 6.39E-112 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS06365 f0e6c284f5e433b3f7ef6a7942e5a835 395 Gene3D G3DSA:3.40.640.10 45 275 1.9E-74 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS06365 f0e6c284f5e433b3f7ef6a7942e5a835 395 Gene3D G3DSA:3.90.1150.10 276 394 4.5E-36 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS06365 f0e6c284f5e433b3f7ef6a7942e5a835 395 Pfam PF00155 Aminotransferase class I and II 32 389 1.4E-71 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 L21SP3_RS02270 a20f6033cf684e1bb8094b3e591eb1cc 796 SUPERFAMILY SSF49899 538 749 6.15E-32 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS02270 a20f6033cf684e1bb8094b3e591eb1cc 796 Gene3D G3DSA:2.60.120.200 106 297 2.9E-4 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS02270 a20f6033cf684e1bb8094b3e591eb1cc 796 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 601 745 1.2E-24 T 09-03-2017 L21SP3_RS02270 a20f6033cf684e1bb8094b3e591eb1cc 796 SUPERFAMILY SSF48726 435 526 9.4E-12 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS02270 a20f6033cf684e1bb8094b3e591eb1cc 796 SMART SM00409 441 540 4.7E-5 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS02270 a20f6033cf684e1bb8094b3e591eb1cc 796 Gene3D G3DSA:2.60.40.10 434 529 2.5E-10 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS02270 a20f6033cf684e1bb8094b3e591eb1cc 796 Pfam PF13927 Immunoglobulin domain 435 524 1.9E-9 T 09-03-2017 L21SP3_RS02270 a20f6033cf684e1bb8094b3e591eb1cc 796 SMART SM00408 447 527 0.0012 T 09-03-2017 IPR003598 Immunoglobulin subtype 2 L21SP3_RS02270 a20f6033cf684e1bb8094b3e591eb1cc 796 SMART SM00560 602 742 0.0017 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS02270 a20f6033cf684e1bb8094b3e591eb1cc 796 Gene3D G3DSA:2.60.120.200 531 748 3.3E-32 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 PRINTS PR01959 SuhB family inositol monophosphatase signature 99 118 1.3E-8 T 09-03-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 PRINTS PR01959 SuhB family inositol monophosphatase signature 151 177 1.3E-8 T 09-03-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 PRINTS PR01959 SuhB family inositol monophosphatase signature 14 36 1.3E-8 T 09-03-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 PRINTS PR01959 SuhB family inositol monophosphatase signature 193 205 1.3E-8 T 09-03-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 Pfam PF00459 Inositol monophosphatase family 7 251 5.7E-55 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 SUPERFAMILY SSF56655 3 252 5.24E-74 T 09-03-2017 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 Gene3D G3DSA:3.30.540.10 3 144 2.6E-44 T 09-03-2017 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 PRINTS PR00377 Inositol monophosphatase superfamily signature 76 92 3.5E-44 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 PRINTS PR00377 Inositol monophosphatase superfamily signature 203 227 3.5E-44 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 PRINTS PR00377 Inositol monophosphatase superfamily signature 35 55 3.5E-44 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 PRINTS PR00377 Inositol monophosphatase superfamily signature 172 193 3.5E-44 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 PRINTS PR00377 Inositol monophosphatase superfamily signature 57 73 3.5E-44 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 PRINTS PR00377 Inositol monophosphatase superfamily signature 125 148 3.5E-44 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 Gene3D G3DSA:3.40.190.80 145 253 1.5E-32 T 09-03-2017 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 206 220 - T 09-03-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 L21SP3_RS04185 3181c088ffc035e43daa36f906d8698c 253 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 76 89 - T 09-03-2017 IPR020583 Inositol monophosphatase, metal-binding site L21SP3_RS04720 4fe729d57b03c07b67521e140fde7dee 559 ProSitePatterns PS00149 Sulfatases signature 2. 129 139 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS04720 4fe729d57b03c07b67521e140fde7dee 559 Gene3D G3DSA:3.40.720.10 41 475 2.7E-116 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS04720 4fe729d57b03c07b67521e140fde7dee 559 Gene3D G3DSA:3.30.1120.10 481 554 7.5E-21 T 09-03-2017 L21SP3_RS04720 4fe729d57b03c07b67521e140fde7dee 559 SUPERFAMILY SSF53649 41 551 7.12E-137 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS04720 4fe729d57b03c07b67521e140fde7dee 559 Pfam PF00884 Sulfatase 43 450 8.4E-74 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS11215 e861347c06c9328117d184eb63517f9c 1141 Pfam PF15892 BNR repeat-containing family member 49 320 1.5E-44 T 09-03-2017 L21SP3_RS11215 e861347c06c9328117d184eb63517f9c 1141 Pfam PF07470 Glycosyl Hydrolase Family 88 448 775 7.5E-86 T 09-03-2017 IPR010905 Glycosyl hydrolase, family 88 L21SP3_RS11215 e861347c06c9328117d184eb63517f9c 1141 Pfam PF16153 Domain of unknown function (DUF4861) 801 1137 2.2E-69 T 09-03-2017 IPR032342 Protein of unknown function DUF4861 L21SP3_RS11215 e861347c06c9328117d184eb63517f9c 1141 SUPERFAMILY SSF75005 33 158 2.67E-5 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS11215 e861347c06c9328117d184eb63517f9c 1141 SUPERFAMILY SSF75005 213 293 2.67E-5 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS11215 e861347c06c9328117d184eb63517f9c 1141 Gene3D G3DSA:1.50.10.10 439 775 2.9E-89 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS11215 e861347c06c9328117d184eb63517f9c 1141 SUPERFAMILY SSF48208 455 776 1.36E-49 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS04740 e3d8049dc3e7419765df306361e05a55 222 Pfam PF02397 Bacterial sugar transferase 6 200 6.5E-49 T 09-03-2017 IPR003362 Bacterial sugar transferase L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 5 406 1.4E-112 T 09-03-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 SUPERFAMILY SSF50465 307 408 1.01E-19 T 09-03-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 Pfam PF03143 Elongation factor Tu C-terminal domain 310 408 3.4E-6 T 09-03-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 SUPERFAMILY SSF52540 2 231 3.34E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 PRINTS PR00315 GTP-binding elongation factor signature 6 19 7.4E-19 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 PRINTS PR00315 GTP-binding elongation factor signature 101 112 7.4E-19 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 PRINTS PR00315 GTP-binding elongation factor signature 85 95 7.4E-19 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 PRINTS PR00315 GTP-binding elongation factor signature 138 147 7.4E-19 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 PRINTS PR00315 GTP-binding elongation factor signature 65 73 7.4E-19 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 Pfam PF00009 Elongation factor Tu GTP binding domain 3 188 9.4E-49 T 09-03-2017 L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 SUPERFAMILY SSF50447 216 301 3.95E-16 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 Gene3D G3DSA:2.40.30.10 217 313 2.1E-20 T 09-03-2017 L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 Gene3D G3DSA:2.40.30.10 314 408 1.1E-13 T 09-03-2017 L21SP3_RS01115 5cd85a2a69726f1643957339913df22e 410 Gene3D G3DSA:3.40.50.300 3 209 5.6E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11170 f55aad9c95052da534edf27b84a6819c 325 Gene3D G3DSA:2.120.10.10 12 295 3.4E-16 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS11170 f55aad9c95052da534edf27b84a6819c 325 SUPERFAMILY SSF50939 12 126 2.45E-12 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS01855 2d640c16ff6fb4a5275ba7686166ea27 228 SUPERFAMILY SSF52540 4 228 1.59E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01855 2d640c16ff6fb4a5275ba7686166ea27 228 SMART SM00382 33 226 3.4E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS01855 2d640c16ff6fb4a5275ba7686166ea27 228 Pfam PF00005 ABC transporter 24 178 1.2E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS01855 2d640c16ff6fb4a5275ba7686166ea27 228 Gene3D G3DSA:3.40.50.300 2 228 4.7E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01855 2d640c16ff6fb4a5275ba7686166ea27 228 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS08695 e356d351c482769b4bc2955e9997c0fe 293 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 293 1.9E-67 T 09-03-2017 IPR005229 Conserved hypothetical protein CHP00255 L21SP3_RS08695 e356d351c482769b4bc2955e9997c0fe 293 Pfam PF08340 Domain of unknown function (DUF1732) 210 293 1.4E-34 T 09-03-2017 IPR013551 Domain of unknown function DUF1732 L21SP3_RS08695 e356d351c482769b4bc2955e9997c0fe 293 Pfam PF03755 YicC-like family, N-terminal region 3 155 6.8E-33 T 09-03-2017 IPR013527 YicC-like, N-terminal L21SP3_RS07425 da42f021b4cd6cadc4343ee480162a31 319 Gene3D G3DSA:2.160.20.10 114 235 3.7E-8 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS07425 da42f021b4cd6cadc4343ee480162a31 319 SUPERFAMILY SSF51126 82 248 7.73E-7 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS07425 da42f021b4cd6cadc4343ee480162a31 319 Pfam PF03718 Glycosyl hydrolase family 49 110 238 1.9E-6 T 09-03-2017 IPR005192 Glycoside hydrolase, family 49 GO:0004553 L21SP3_RS09995 02ddf4e044c26b2f60a2abad55feafa8 760 Gene3D G3DSA:3.20.20.80 345 658 2.6E-15 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS09995 02ddf4e044c26b2f60a2abad55feafa8 760 Gene3D G3DSA:1.10.1330.10 246 304 4.8E-4 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS09995 02ddf4e044c26b2f60a2abad55feafa8 760 SUPERFAMILY SSF51445 331 657 2.07E-28 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS05680 53abec4502991b6aa3c90fb35fb55325 294 Gene3D G3DSA:3.40.50.150 30 87 5.8E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS05680 53abec4502991b6aa3c90fb35fb55325 294 Gene3D G3DSA:3.40.50.150 191 294 5.8E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS05680 53abec4502991b6aa3c90fb35fb55325 294 PIRSF PIRSF000398 26 294 1.3E-42 T 09-03-2017 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 L21SP3_RS05680 53abec4502991b6aa3c90fb35fb55325 294 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 56 70 8.8E-11 T 09-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP3_RS05680 53abec4502991b6aa3c90fb35fb55325 294 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 207 219 8.8E-11 T 09-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP3_RS05680 53abec4502991b6aa3c90fb35fb55325 294 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 76 89 8.8E-11 T 09-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP3_RS05680 53abec4502991b6aa3c90fb35fb55325 294 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 35 51 8.8E-11 T 09-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP3_RS05680 53abec4502991b6aa3c90fb35fb55325 294 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 35 274 2.2E-18 T 09-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP3_RS05680 53abec4502991b6aa3c90fb35fb55325 294 SUPERFAMILY SSF53335 31 294 9.09E-45 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS07405 b5745a814984f3a4c48c2bf89e04ddbb 298 Pfam PF13649 Methyltransferase domain 80 170 5.5E-17 T 09-03-2017 L21SP3_RS07405 b5745a814984f3a4c48c2bf89e04ddbb 298 SUPERFAMILY SSF53335 42 185 1.53E-32 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS07405 b5745a814984f3a4c48c2bf89e04ddbb 298 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 164 178 - T 09-03-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 L21SP3_RS07405 b5745a814984f3a4c48c2bf89e04ddbb 298 Gene3D G3DSA:3.40.50.150 41 187 1.1E-30 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 SUPERFAMILY SSF52279 564 723 9.68E-51 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 SUPERFAMILY SSF52279 339 409 9.68E-51 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 SMART SM00758 428 564 1.3E-30 T 09-03-2017 IPR011658 PA14 domain L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 PRINTS PR00133 Glycosyl hydrolase family 3 signature 89 108 1.9E-33 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 PRINTS PR00133 Glycosyl hydrolase family 3 signature 166 182 1.9E-33 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 PRINTS PR00133 Glycosyl hydrolase family 3 signature 64 80 1.9E-33 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 PRINTS PR00133 Glycosyl hydrolase family 3 signature 236 254 1.9E-33 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 PRINTS PR00133 Glycosyl hydrolase family 3 signature 135 151 1.9E-33 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 SUPERFAMILY SSF51445 27 337 5.16E-96 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 339 720 3.4E-50 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 236 253 - T 09-03-2017 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 31 304 9.1E-50 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 Pfam PF07691 PA14 domain 429 556 3.7E-31 T 09-03-2017 IPR011658 PA14 domain L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 SMART SM01217 754 824 9.6E-29 T 09-03-2017 IPR026891 Fibronectin type III-like domain L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 Gene3D G3DSA:3.20.20.300 32 318 1.1E-101 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 Gene3D G3DSA:3.40.50.1700 325 410 5.9E-65 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 Gene3D G3DSA:3.40.50.1700 564 723 5.9E-65 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP3_RS03880 b71a0900e4fd9ab3c6886bdcc5624760 835 Pfam PF14310 Fibronectin type III-like domain 754 824 9.9E-23 T 09-03-2017 IPR026891 Fibronectin type III-like domain L21SP3_RS08755 9602603e53e1ca30b38c1e1fc7161f0c 337 Gene3D G3DSA:3.40.50.720 1 159 7.1E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS08755 9602603e53e1ca30b38c1e1fc7161f0c 337 SMART SM00859 5 143 1.7E-39 T 09-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 L21SP3_RS08755 9602603e53e1ca30b38c1e1fc7161f0c 337 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 4 337 37.174 T 09-03-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 L21SP3_RS08755 9602603e53e1ca30b38c1e1fc7161f0c 337 SUPERFAMILY SSF55347 151 311 6.54E-46 T 09-03-2017 L21SP3_RS08755 9602603e53e1ca30b38c1e1fc7161f0c 337 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 146 162 - T 09-03-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 L21SP3_RS08755 9602603e53e1ca30b38c1e1fc7161f0c 337 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 142 2.6E-28 T 09-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 L21SP3_RS08755 9602603e53e1ca30b38c1e1fc7161f0c 337 SUPERFAMILY SSF51735 2 173 1.94E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS08755 9602603e53e1ca30b38c1e1fc7161f0c 337 Gene3D G3DSA:3.30.360.10 160 311 2.2E-51 T 09-03-2017 L21SP3_RS08755 9602603e53e1ca30b38c1e1fc7161f0c 337 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 161 314 1.6E-12 T 09-03-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 L21SP3_RS08755 9602603e53e1ca30b38c1e1fc7161f0c 337 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 4 336 1.0E-113 T 09-03-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 Pfam PF01624 MutS domain I 10 121 3.8E-44 T 09-03-2017 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 702 718 - T 09-03-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 Pfam PF05192 MutS domain III 282 572 6.8E-37 T 09-03-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 Gene3D G3DSA:3.40.50.300 580 811 9.8E-88 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 Gene3D G3DSA:3.30.420.110 128 267 2.6E-35 T 09-03-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 SUPERFAMILY SSF52540 580 812 1.56E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 9 868 2.1E-301 T 09-03-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 Gene3D G3DSA:3.40.1170.10 5 121 2.0E-51 T 09-03-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 Gene3D G3DSA:1.10.1420.10 275 481 1.1E-53 T 09-03-2017 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 SUPERFAMILY SSF53150 116 278 3.79E-37 T 09-03-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 SMART SM00533 296 604 1.0E-95 T 09-03-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 Pfam PF05188 MutS domain II 130 265 8.8E-20 T 09-03-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 Pfam PF00488 MutS domain V 624 811 2.1E-88 T 09-03-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 SMART SM00534 621 808 3.0E-120 T 09-03-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 SUPERFAMILY SSF55271 4 117 3.4E-43 T 09-03-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 9 863 24.671 T 09-03-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 SUPERFAMILY SSF48334 279 578 3.27E-86 T 09-03-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 PIRSF PIRSF037677 3 872 1.0E-185 T 09-03-2017 L21SP3_RS11615 61e1b4566aec779fa5cd38e7a0a7c6d5 876 Pfam PF05190 MutS family domain IV 441 532 1.7E-30 T 09-03-2017 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 L21SP3_RS01910 ec1d81d3fbab710acb93f78f36a8dca2 364 SUPERFAMILY SSF51726 20 285 1.54E-8 T 09-03-2017 L21SP3_RS01910 ec1d81d3fbab710acb93f78f36a8dca2 364 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 20 291 3.8E-7 T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 L21SP3_RS01910 ec1d81d3fbab710acb93f78f36a8dca2 364 Gene3D G3DSA:3.20.20.210 19 294 3.0E-8 T 09-03-2017 L21SP3_RS00665 39dd0d8b6c8ebaa4b9d02f95fafd443d 364 SUPERFAMILY SSF51395 1 353 5.5E-83 T 09-03-2017 L21SP3_RS00665 39dd0d8b6c8ebaa4b9d02f95fafd443d 364 Gene3D G3DSA:3.20.20.70 1 357 2.2E-92 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS00665 39dd0d8b6c8ebaa4b9d02f95fafd443d 364 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 9 334 1.4E-45 T 09-03-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 L21SP3_RS05705 52e2d49039aa05e73babe61c1d976008 349 SUPERFAMILY SSF52922 239 347 2.36E-23 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP3_RS05705 52e2d49039aa05e73babe61c1d976008 349 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 246 340 9.0E-26 T 09-03-2017 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II L21SP3_RS05705 52e2d49039aa05e73babe61c1d976008 349 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 15 229 4.1E-54 T 09-03-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 L21SP3_RS05705 52e2d49039aa05e73babe61c1d976008 349 Gene3D G3DSA:3.40.50.970 3 189 6.9E-70 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS05705 52e2d49039aa05e73babe61c1d976008 349 Gene3D G3DSA:3.40.50.920 239 347 9.2E-22 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP3_RS05705 52e2d49039aa05e73babe61c1d976008 349 SUPERFAMILY SSF52518 3 223 2.0E-61 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS00110 e793d3c84f360a7b07d42ebcd1446c41 429 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 166 372 8.4E-21 T 09-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS00110 e793d3c84f360a7b07d42ebcd1446c41 429 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 428 214.671 T 09-03-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 L21SP3_RS00110 e793d3c84f360a7b07d42ebcd1446c41 429 Gene3D G3DSA:3.40.50.300 142 426 7.7E-96 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00110 e793d3c84f360a7b07d42ebcd1446c41 429 SMART SM00959 15 57 1.4E-9 T 09-03-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 L21SP3_RS00110 e793d3c84f360a7b07d42ebcd1446c41 429 SMART SM00357 62 128 1.2E-16 T 09-03-2017 IPR011129 Cold shock protein GO:0003676 L21SP3_RS00110 e793d3c84f360a7b07d42ebcd1446c41 429 SMART SM00382 177 364 2.9E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS00110 e793d3c84f360a7b07d42ebcd1446c41 429 SUPERFAMILY SSF50249 60 135 1.88E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS00110 e793d3c84f360a7b07d42ebcd1446c41 429 SUPERFAMILY SSF68912 13 55 1.61E-7 T 09-03-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 L21SP3_RS00110 e793d3c84f360a7b07d42ebcd1446c41 429 Pfam PF07497 Rho termination factor, RNA-binding domain 62 135 7.4E-32 T 09-03-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 L21SP3_RS00110 e793d3c84f360a7b07d42ebcd1446c41 429 Pfam PF07498 Rho termination factor, N-terminal domain 15 52 3.6E-9 T 09-03-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 L21SP3_RS00110 e793d3c84f360a7b07d42ebcd1446c41 429 Gene3D G3DSA:2.40.50.140 13 135 2.9E-47 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS00110 e793d3c84f360a7b07d42ebcd1446c41 429 TIGRFAM TIGR00767 rho: transcription termination factor Rho 14 426 6.2E-198 T 09-03-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 L21SP3_RS00110 e793d3c84f360a7b07d42ebcd1446c41 429 SUPERFAMILY SSF52540 101 380 2.89E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05085 4c4642f9ff196772c427ef37d52936d5 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.7E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS05085 4c4642f9ff196772c427ef37d52936d5 422 Pfam PF01609 Transposase DDE domain 275 412 1.4E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS01870 4c4642f9ff196772c427ef37d52936d5 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.7E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS01870 4c4642f9ff196772c427ef37d52936d5 422 Pfam PF01609 Transposase DDE domain 275 412 1.4E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS06125 f1b32233b508ddc560e3ea55db55c59a 168 SUPERFAMILY SSF54211 84 163 7.08E-24 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS06125 f1b32233b508ddc560e3ea55db55c59a 168 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 14 167 8.2E-61 T 09-03-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 L21SP3_RS06125 f1b32233b508ddc560e3ea55db55c59a 168 Gene3D G3DSA:3.30.160.20 15 77 1.6E-26 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain L21SP3_RS06125 f1b32233b508ddc560e3ea55db55c59a 168 ProSitePatterns PS00585 Ribosomal protein S5 signature. 33 65 - T 09-03-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site L21SP3_RS06125 f1b32233b508ddc560e3ea55db55c59a 168 Pfam PF03719 Ribosomal protein S5, C-terminal domain 92 162 1.5E-26 T 09-03-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06125 f1b32233b508ddc560e3ea55db55c59a 168 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 168 31.303 T 09-03-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 L21SP3_RS06125 f1b32233b508ddc560e3ea55db55c59a 168 Pfam PF00333 Ribosomal protein S5, N-terminal domain 16 79 9.1E-25 T 09-03-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06125 f1b32233b508ddc560e3ea55db55c59a 168 SUPERFAMILY SSF54768 15 80 2.93E-19 T 09-03-2017 L21SP3_RS06125 f1b32233b508ddc560e3ea55db55c59a 168 Gene3D G3DSA:3.30.230.10 81 163 1.1E-29 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP3_RS02450 b232145c9da865077aa6f266d171bfd3 498 Pfam PF00082 Subtilase family 165 435 4.8E-44 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 L21SP3_RS02450 b232145c9da865077aa6f266d171bfd3 498 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 386 396 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site L21SP3_RS02450 b232145c9da865077aa6f266d171bfd3 498 SUPERFAMILY SSF52743 148 444 1.57E-74 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 L21SP3_RS02450 b232145c9da865077aa6f266d171bfd3 498 Gene3D G3DSA:3.40.50.200 111 443 5.3E-84 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 L21SP3_RS02450 b232145c9da865077aa6f266d171bfd3 498 PRINTS PR00723 Subtilisin serine protease family (S8) signature 385 401 2.1E-15 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related L21SP3_RS02450 b232145c9da865077aa6f266d171bfd3 498 PRINTS PR00723 Subtilisin serine protease family (S8) signature 208 221 2.1E-15 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related L21SP3_RS02450 b232145c9da865077aa6f266d171bfd3 498 PRINTS PR00723 Subtilisin serine protease family (S8) signature 162 181 2.1E-15 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related L21SP3_RS02450 b232145c9da865077aa6f266d171bfd3 498 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 167 178 - T 09-03-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site L21SP3_RS03650 bc4830254ce52abe16edc0753de663d3 256 Gene3D G3DSA:2.10.109.10 129 241 5.1E-21 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain L21SP3_RS03650 bc4830254ce52abe16edc0753de663d3 256 Pfam PF13560 Helix-turn-helix domain 3 65 1.2E-10 T 09-03-2017 L21SP3_RS03650 bc4830254ce52abe16edc0753de663d3 256 SUPERFAMILY SSF51306 129 239 2.35E-21 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C L21SP3_RS03650 bc4830254ce52abe16edc0753de663d3 256 SMART SM00530 6 63 5.3E-12 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP3_RS03650 bc4830254ce52abe16edc0753de663d3 256 Pfam PF00717 Peptidase S24-like 171 234 5.0E-12 T 09-03-2017 IPR019759 Peptidase S24/S26A/S26B L21SP3_RS03650 bc4830254ce52abe16edc0753de663d3 256 Gene3D G3DSA:1.10.260.40 3 88 1.2E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS03650 bc4830254ce52abe16edc0753de663d3 256 SUPERFAMILY SSF47413 1 69 1.64E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS08205 2f7c1683bf4ebec884c46ed9933774fd 341 Pfam PF00665 Integrase core domain 178 280 8.5E-13 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS08205 2f7c1683bf4ebec884c46ed9933774fd 341 ProSitePatterns PS01043 Transposases, IS30 family, signature. 268 284 - T 09-03-2017 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 L21SP3_RS08205 2f7c1683bf4ebec884c46ed9933774fd 341 SUPERFAMILY SSF53098 175 321 1.35E-25 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS08205 2f7c1683bf4ebec884c46ed9933774fd 341 Gene3D G3DSA:3.30.420.10 176 322 3.8E-14 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS08205 2f7c1683bf4ebec884c46ed9933774fd 341 Pfam PF13936 Helix-turn-helix domain 4 45 5.0E-14 T 09-03-2017 IPR025246 Transposase IS30-like HTH domain L21SP3_RS03560 1804a9a3b2c6f63459a172df7ac94646 713 Gene3D G3DSA:3.40.50.300 473 704 1.1E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03560 1804a9a3b2c6f63459a172df7ac94646 713 Pfam PF00005 ABC transporter 491 639 4.4E-34 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS03560 1804a9a3b2c6f63459a172df7ac94646 713 SUPERFAMILY SSF90123 183 460 1.7E-58 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 L21SP3_RS03560 1804a9a3b2c6f63459a172df7ac94646 713 SUPERFAMILY SSF90123 5 44 1.7E-58 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 L21SP3_RS03560 1804a9a3b2c6f63459a172df7ac94646 713 ProSitePatterns PS00211 ABC transporters family signature. 612 626 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS03560 1804a9a3b2c6f63459a172df7ac94646 713 SMART SM00382 500 686 2.4E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS03560 1804a9a3b2c6f63459a172df7ac94646 713 SUPERFAMILY SSF52540 466 711 1.77E-88 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03560 1804a9a3b2c6f63459a172df7ac94646 713 Pfam PF00664 ABC transporter transmembrane region 188 423 2.0E-33 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 L21SP3_RS03560 1804a9a3b2c6f63459a172df7ac94646 713 Gene3D G3DSA:1.20.1560.10 4 56 3.0E-61 T 09-03-2017 L21SP3_RS03560 1804a9a3b2c6f63459a172df7ac94646 713 Gene3D G3DSA:1.20.1560.10 190 458 3.0E-61 T 09-03-2017 L21SP3_RS09170 7ff6a588d62cb12912dc16b731ab6d1a 304 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 17 292 24.462 T 09-03-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 L21SP3_RS09170 7ff6a588d62cb12912dc16b731ab6d1a 304 SUPERFAMILY SSF55060 180 273 1.58E-9 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain L21SP3_RS09170 7ff6a588d62cb12912dc16b731ab6d1a 304 PIRSF PIRSF010376 15 302 8.1E-64 T 09-03-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 L21SP3_RS09170 7ff6a588d62cb12912dc16b731ab6d1a 304 Pfam PF00288 GHMP kinases N terminal domain 102 143 6.9E-7 T 09-03-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 L21SP3_RS09170 7ff6a588d62cb12912dc16b731ab6d1a 304 Gene3D G3DSA:3.30.230.10 19 175 2.2E-41 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP3_RS09170 7ff6a588d62cb12912dc16b731ab6d1a 304 SUPERFAMILY SSF54211 17 173 5.77E-31 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS09170 7ff6a588d62cb12912dc16b731ab6d1a 304 Gene3D G3DSA:3.30.70.890 181 274 2.9E-10 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain L21SP3_RS09170 7ff6a588d62cb12912dc16b731ab6d1a 304 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 18 277 1.2E-48 T 09-03-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 L21SP3_RS07850 f55ffe322c006cbc3a604d2c35897853 157 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 09-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site L21SP3_RS07850 f55ffe322c006cbc3a604d2c35897853 157 Gene3D G3DSA:1.10.10.10 7 143 7.7E-35 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS07850 f55ffe322c006cbc3a604d2c35897853 157 SUPERFAMILY SSF46785 7 145 6.92E-32 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS07850 f55ffe322c006cbc3a604d2c35897853 157 Pfam PF01047 MarR family 37 94 8.7E-15 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 L21SP3_RS07850 f55ffe322c006cbc3a604d2c35897853 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 7.5E-8 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 L21SP3_RS07850 f55ffe322c006cbc3a604d2c35897853 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 7.5E-8 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 L21SP3_RS07850 f55ffe322c006cbc3a604d2c35897853 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 7.5E-8 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 L21SP3_RS07850 f55ffe322c006cbc3a604d2c35897853 157 SMART SM00347 29 129 1.4E-25 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 L21SP3_RS11545 2d349f96fdcae65b78d4aba23c7ba843 285 Pfam PF00849 RNA pseudouridylate synthase 18 162 2.9E-17 T 09-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS11545 2d349f96fdcae65b78d4aba23c7ba843 285 SUPERFAMILY SSF55120 8 220 6.96E-32 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS11390 3580d403dd6326a07845401d7afd3c2f 129 Gene3D G3DSA:1.10.1200.10 2 68 4.1E-19 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS11390 3580d403dd6326a07845401d7afd3c2f 129 ProSitePatterns PS00012 Phosphopantetheine attachment site. 36 51 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site L21SP3_RS11390 3580d403dd6326a07845401d7afd3c2f 129 SUPERFAMILY SSF47336 2 79 5.63E-18 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS11390 3580d403dd6326a07845401d7afd3c2f 129 Pfam PF00550 Phosphopantetheine attachment site 10 70 2.4E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS11390 3580d403dd6326a07845401d7afd3c2f 129 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 15.283 T 09-03-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS06845 2b80ce0032e1e05035a9df648227cf0f 200 Pfam PF02545 Maf-like protein 5 190 1.5E-43 T 09-03-2017 IPR003697 Maf-like protein GO:0005737 L21SP3_RS06845 2b80ce0032e1e05035a9df648227cf0f 200 SUPERFAMILY SSF52972 2 190 3.47E-48 T 09-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like L21SP3_RS06845 2b80ce0032e1e05035a9df648227cf0f 200 PIRSF PIRSF006305 1 197 2.5E-45 T 09-03-2017 IPR003697 Maf-like protein GO:0005737 L21SP3_RS06845 2b80ce0032e1e05035a9df648227cf0f 200 Hamap MF_00528 Septum formation protein Maf [maf]. 5 195 26.028 T 09-03-2017 IPR003697 Maf-like protein GO:0005737 L21SP3_RS06845 2b80ce0032e1e05035a9df648227cf0f 200 Gene3D G3DSA:3.90.950.10 4 193 2.0E-54 T 09-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like L21SP3_RS06845 2b80ce0032e1e05035a9df648227cf0f 200 TIGRFAM TIGR00172 maf: septum formation protein Maf 4 189 6.4E-41 T 09-03-2017 IPR003697 Maf-like protein GO:0005737 L21SP3_RS02695 e4bd86d7e6871244b35973221f13a5f1 434 PIRSF PIRSF006444 1 433 7.7E-177 T 09-03-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 L21SP3_RS02695 e4bd86d7e6871244b35973221f13a5f1 434 SUPERFAMILY SSF56801 48 380 9.81E-58 T 09-03-2017 L21SP3_RS02695 e4bd86d7e6871244b35973221f13a5f1 434 Gene3D G3DSA:3.40.50.980 83 241 1.6E-13 T 09-03-2017 L21SP3_RS02695 e4bd86d7e6871244b35973221f13a5f1 434 Gene3D G3DSA:3.30.300.30 325 431 1.2E-34 T 09-03-2017 L21SP3_RS02695 e4bd86d7e6871244b35973221f13a5f1 434 Pfam PF14535 AMP-binding enzyme C-terminal domain 335 431 1.3E-28 T 09-03-2017 IPR028154 AMP-dependent ligase, C-terminal L21SP3_RS02695 e4bd86d7e6871244b35973221f13a5f1 434 Pfam PF00501 AMP-binding enzyme 69 285 2.4E-15 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 L21SP3_RS05585 4f1ca17361f5d26508a867c15899234f 333 Gene3D G3DSA:1.10.1040.10 30 326 1.9E-103 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 L21SP3_RS05585 4f1ca17361f5d26508a867c15899234f 333 SUPERFAMILY SSF51735 3 183 2.08E-63 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS05585 4f1ca17361f5d26508a867c15899234f 333 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 6.7E-65 T 09-03-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 L21SP3_RS05585 4f1ca17361f5d26508a867c15899234f 333 SUPERFAMILY SSF48179 185 331 2.21E-68 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 L21SP3_RS05585 4f1ca17361f5d26508a867c15899234f 333 PIRSF PIRSF000116 1 324 2.6E-48 T 09-03-2017 IPR014359 Ketol-acid reductoisomerase, bacteria GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 L21SP3_RS05585 4f1ca17361f5d26508a867c15899234f 333 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 327 5.2E-65 T 09-03-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 L21SP3_RS05585 4f1ca17361f5d26508a867c15899234f 333 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 2.9E-123 T 09-03-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 L21SP3_RS05585 4f1ca17361f5d26508a867c15899234f 333 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 2 329 41.497 T 09-03-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 L21SP3_RS01210 a90631fc4b1f841d10e6c9c079b1e52e 229 SUPERFAMILY SSF53639 1 220 3.92E-63 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal L21SP3_RS01210 a90631fc4b1f841d10e6c9c079b1e52e 229 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 193 2.4E-42 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal L21SP3_RS01210 a90631fc4b1f841d10e6c9c079b1e52e 229 SMART SM01007 7 195 7.2E-60 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal L21SP3_RS01210 a90631fc4b1f841d10e6c9c079b1e52e 229 Gene3D G3DSA:3.40.225.10 2 228 7.1E-66 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal L21SP3_RS02095 23902f7833733db2e590f5655d5cf0d6 182 Gene3D G3DSA:3.10.430.100 71 152 8.3E-20 T 09-03-2017 IPR020069 Ribosomal protein L9, C-terminal L21SP3_RS02095 23902f7833733db2e590f5655d5cf0d6 182 TIGRFAM TIGR00158 L9: ribosomal protein bL9 7 152 9.7E-35 T 09-03-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS02095 23902f7833733db2e590f5655d5cf0d6 182 ProSitePatterns PS00651 Ribosomal protein L9 signature. 19 46 - T 09-03-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02095 23902f7833733db2e590f5655d5cf0d6 182 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 7 152 21.801 T 09-03-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS02095 23902f7833733db2e590f5655d5cf0d6 182 Pfam PF01281 Ribosomal protein L9, N-terminal domain 7 52 3.5E-17 T 09-03-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02095 23902f7833733db2e590f5655d5cf0d6 182 Pfam PF03948 Ribosomal protein L9, C-terminal domain 73 150 1.1E-18 T 09-03-2017 IPR020069 Ribosomal protein L9, C-terminal L21SP3_RS02095 23902f7833733db2e590f5655d5cf0d6 182 SUPERFAMILY SSF55653 69 152 1.96E-16 T 09-03-2017 IPR020069 Ribosomal protein L9, C-terminal L21SP3_RS02095 23902f7833733db2e590f5655d5cf0d6 182 SUPERFAMILY SSF55658 7 61 3.84E-15 T 09-03-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal L21SP3_RS02095 23902f7833733db2e590f5655d5cf0d6 182 Gene3D G3DSA:3.40.5.10 7 58 1.4E-19 T 09-03-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS11770 cfe2b39c62f80b460c33374c53498014 279 Gene3D G3DSA:1.10.600.10 7 227 2.9E-39 T 09-03-2017 IPR008949 Isoprenoid synthase domain L21SP3_RS11770 cfe2b39c62f80b460c33374c53498014 279 SUPERFAMILY SSF48576 41 230 3.06E-39 T 09-03-2017 IPR008949 Isoprenoid synthase domain L21SP3_RS11770 cfe2b39c62f80b460c33374c53498014 279 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 78 92 - T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 L21SP3_RS11770 cfe2b39c62f80b460c33374c53498014 279 Pfam PF00348 Polyprenyl synthetase 41 211 6.3E-28 T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 L21SP3_RS09770 d0f79d130ed66e080e11baa9ee9c3c88 303 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 26 32 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 L21SP3_RS09770 d0f79d130ed66e080e11baa9ee9c3c88 303 SUPERFAMILY SSF53335 3 236 4.13E-67 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS09770 d0f79d130ed66e080e11baa9ee9c3c88 303 Pfam PF01555 DNA methylase 23 232 2.4E-59 T 09-03-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 L21SP3_RS09770 d0f79d130ed66e080e11baa9ee9c3c88 303 Gene3D G3DSA:3.40.50.150 3 240 1.9E-71 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS09770 d0f79d130ed66e080e11baa9ee9c3c88 303 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 192 210 5.2E-37 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS09770 d0f79d130ed66e080e11baa9ee9c3c88 303 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 22 36 5.2E-37 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS09770 d0f79d130ed66e080e11baa9ee9c3c88 303 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 57 77 5.2E-37 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS09770 d0f79d130ed66e080e11baa9ee9c3c88 303 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 173 190 5.2E-37 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS09770 d0f79d130ed66e080e11baa9ee9c3c88 303 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 215 235 5.2E-37 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS04430 957d70374bd3bd69aaf0d3b5b5c6ce13 84 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 28 82 1.0E-14 T 09-03-2017 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 L21SP3_RS04430 957d70374bd3bd69aaf0d3b5b5c6ce13 84 SUPERFAMILY SSF81333 13 82 1.96E-15 T 09-03-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 L21SP3_RS04430 957d70374bd3bd69aaf0d3b5b5c6ce13 84 Hamap MF_01396 ATP synthase subunit c [atpH]. 15 83 14.766 T 09-03-2017 L21SP3_RS04430 957d70374bd3bd69aaf0d3b5b5c6ce13 84 ProSitePatterns PS00605 ATP synthase c subunit signature. 46 67 - T 09-03-2017 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 L21SP3_RS04430 957d70374bd3bd69aaf0d3b5b5c6ce13 84 PRINTS PR00124 ATP synthase C subunit signature 39 54 6.4E-12 T 09-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 L21SP3_RS04430 957d70374bd3bd69aaf0d3b5b5c6ce13 84 PRINTS PR00124 ATP synthase C subunit signature 56 81 6.4E-12 T 09-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 L21SP3_RS04430 957d70374bd3bd69aaf0d3b5b5c6ce13 84 PRINTS PR00124 ATP synthase C subunit signature 18 37 6.4E-12 T 09-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 L21SP3_RS04430 957d70374bd3bd69aaf0d3b5b5c6ce13 84 Gene3D G3DSA:1.20.20.10 12 82 4.8E-19 T 09-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 L21SP3_RS04430 957d70374bd3bd69aaf0d3b5b5c6ce13 84 Pfam PF00137 ATP synthase subunit C 18 79 1.8E-11 T 09-03-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 L21SP3_RS10820 088795b5601d12584e0e9cfb7965df42 381 SUPERFAMILY SSF54862 337 375 3.77E-9 T 09-03-2017 L21SP3_RS10820 088795b5601d12584e0e9cfb7965df42 381 SUPERFAMILY SSF54862 282 304 3.77E-9 T 09-03-2017 L21SP3_RS10820 088795b5601d12584e0e9cfb7965df42 381 Gene3D G3DSA:1.10.1060.10 340 369 2.7E-4 T 09-03-2017 L21SP3_RS10820 088795b5601d12584e0e9cfb7965df42 381 Pfam PF00248 Aldo/keto reductase family 16 276 5.0E-29 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain L21SP3_RS10820 088795b5601d12584e0e9cfb7965df42 381 Gene3D G3DSA:3.20.20.100 1 269 6.0E-44 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain L21SP3_RS10820 088795b5601d12584e0e9cfb7965df42 381 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 285 296 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS10820 088795b5601d12584e0e9cfb7965df42 381 Pfam PF13534 4Fe-4S dicluster domain 285 359 2.2E-7 T 09-03-2017 L21SP3_RS10820 088795b5601d12584e0e9cfb7965df42 381 SUPERFAMILY SSF51430 1 277 1.31E-49 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain L21SP3_RS10820 088795b5601d12584e0e9cfb7965df42 381 Gene3D G3DSA:1.10.1060.10 270 317 2.0E-5 T 09-03-2017 L21SP3_RS01610 2555f43f9cc8114f537445f14a040c8e 525 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 28 2.5E-4 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal L21SP3_RS01610 2555f43f9cc8114f537445f14a040c8e 525 Pfam PF00884 Sulfatase 163 305 6.0E-27 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS01610 2555f43f9cc8114f537445f14a040c8e 525 Pfam PF00884 Sulfatase 33 140 1.0E-16 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS01610 2555f43f9cc8114f537445f14a040c8e 525 Gene3D G3DSA:3.30.1120.10 361 377 1.8E-21 T 09-03-2017 L21SP3_RS01610 2555f43f9cc8114f537445f14a040c8e 525 Gene3D G3DSA:3.30.1120.10 427 472 1.8E-21 T 09-03-2017 L21SP3_RS01610 2555f43f9cc8114f537445f14a040c8e 525 Gene3D G3DSA:3.40.720.10 164 360 2.0E-39 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS01610 2555f43f9cc8114f537445f14a040c8e 525 SUPERFAMILY SSF53649 425 470 2.04E-91 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS01610 2555f43f9cc8114f537445f14a040c8e 525 SUPERFAMILY SSF53649 32 375 2.04E-91 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS01610 2555f43f9cc8114f537445f14a040c8e 525 Gene3D G3DSA:3.40.720.10 30 157 4.7E-29 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS10685 fa65f5bee6e632fed737bafa1b4774e1 200 Gene3D G3DSA:2.60.120.260 20 177 6.2E-5 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10685 fa65f5bee6e632fed737bafa1b4774e1 200 SUPERFAMILY SSF49785 20 177 4.46E-7 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10685 fa65f5bee6e632fed737bafa1b4774e1 200 Pfam PF07589 PEP-CTERM motif 177 197 1.3E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS10685 fa65f5bee6e632fed737bafa1b4774e1 200 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 177 198 1.3E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 SUPERFAMILY SSF82866 787 1006 6.41E-47 T 09-03-2017 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 SUPERFAMILY SSF82693 40 135 4.24E-20 T 09-03-2017 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 SUPERFAMILY SSF82866 295 490 4.05E-39 T 09-03-2017 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 3.8E-25 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 3.8E-25 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 3.8E-25 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 PRINTS PR00702 Acriflavin resistance protein family signature 536 553 3.8E-25 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 3.8E-25 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.8E-25 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 Gene3D G3DSA:3.30.70.1430 40 141 1.2E-25 T 09-03-2017 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 Pfam PF00873 AcrB/AcrD/AcrF family 4 1002 2.8E-158 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 SUPERFAMILY SSF82693 136 182 4.76E-17 T 09-03-2017 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 SUPERFAMILY SSF82693 268 323 4.76E-17 T 09-03-2017 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 Gene3D G3DSA:1.10.3850.10 795 1004 6.8E-58 T 09-03-2017 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 SUPERFAMILY SSF82714 185 265 1.96E-10 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 SUPERFAMILY SSF82714 706 784 3.14E-8 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 Gene3D G3DSA:3.30.70.1430 553 628 6.8E-5 T 09-03-2017 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 Gene3D G3DSA:3.30.2090.10 188 265 6.8E-12 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 Gene3D G3DSA:3.30.2090.10 709 784 2.0E-4 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 SUPERFAMILY SSF82693 552 624 1.17E-5 T 09-03-2017 L21SP3_RS09085 c164fe35a5825a0cb5323be0076b6a57 1012 Gene3D G3DSA:1.20.1640.10 288 494 3.1E-48 T 09-03-2017 L21SP3_RS01975 6e936cdaee002193f5a531ba2b3aa20d 530 Pfam PF08305 NPCBM/NEW2 domain 436 524 4.4E-7 T 09-03-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module L21SP3_RS01975 6e936cdaee002193f5a531ba2b3aa20d 530 SUPERFAMILY SSF49785 439 525 9.35E-7 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01975 6e936cdaee002193f5a531ba2b3aa20d 530 Pfam PF04773 FecR protein 195 250 1.7E-4 T 09-03-2017 IPR006860 FecR protein L21SP3_RS06320 cba184b77cd6d07cbce7f9f06cc7ab53 570 SUPERFAMILY SSF160246 2 139 2.43E-29 T 09-03-2017 L21SP3_RS06320 cba184b77cd6d07cbce7f9f06cc7ab53 570 Gene3D G3DSA:3.30.450.90 163 285 9.4E-46 T 09-03-2017 L21SP3_RS06320 cba184b77cd6d07cbce7f9f06cc7ab53 570 SMART SM00382 314 436 0.0018 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS06320 cba184b77cd6d07cbce7f9f06cc7ab53 570 Gene3D G3DSA:3.40.50.300 293 565 3.4E-96 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06320 cba184b77cd6d07cbce7f9f06cc7ab53 570 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 40 140 1.6E-20 T 09-03-2017 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 L21SP3_RS06320 cba184b77cd6d07cbce7f9f06cc7ab53 570 Pfam PF00437 Type II/IV secretion system protein 190 453 4.2E-75 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS06320 cba184b77cd6d07cbce7f9f06cc7ab53 570 SUPERFAMILY SSF52540 175 561 4.01E-96 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08705 4eec56100bb90bc4e2567f1a4c17f344 67 SUPERFAMILY SSF63562 8 66 2.62E-8 T 09-03-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 L21SP3_RS08705 4eec56100bb90bc4e2567f1a4c17f344 67 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 2 63 10.581 T 09-03-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS08705 4eec56100bb90bc4e2567f1a4c17f344 67 Gene3D G3DSA:3.90.940.10 8 65 3.3E-5 T 09-03-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 L21SP3_RS05395 13cd81d0e20be7ebaf30dfcd97e4aea6 382 Gene3D G3DSA:3.30.70.830 145 250 3.5E-37 T 09-03-2017 L21SP3_RS05395 13cd81d0e20be7ebaf30dfcd97e4aea6 382 Gene3D G3DSA:3.40.1390.30 13 123 1.2E-38 T 09-03-2017 L21SP3_RS05395 13cd81d0e20be7ebaf30dfcd97e4aea6 382 SUPERFAMILY SSF102705 14 378 2.22E-102 T 09-03-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 L21SP3_RS05395 13cd81d0e20be7ebaf30dfcd97e4aea6 382 Gene3D G3DSA:3.40.1390.30 124 140 6.7E-32 T 09-03-2017 L21SP3_RS05395 13cd81d0e20be7ebaf30dfcd97e4aea6 382 Gene3D G3DSA:3.40.1390.30 251 340 6.7E-32 T 09-03-2017 L21SP3_RS05395 13cd81d0e20be7ebaf30dfcd97e4aea6 382 PIRSF PIRSF037489 11 380 8.5E-111 T 09-03-2017 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria L21SP3_RS05395 13cd81d0e20be7ebaf30dfcd97e4aea6 382 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 13 375 1.4E-55 T 09-03-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 L21SP3_RS05395 13cd81d0e20be7ebaf30dfcd97e4aea6 382 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 18 363 4.3E-69 T 09-03-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 L21SP3_RS08445 f581f7e572a1a22ad409e2b34f0a6747 282 Gene3D G3DSA:3.40.50.1110 50 261 1.0E-15 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS08445 f581f7e572a1a22ad409e2b34f0a6747 282 SUPERFAMILY SSF52266 54 265 1.3E-15 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS00920 2754e3cb65a4fea9287bb16e624d0cb8 715 Gene3D G3DSA:2.30.42.10 302 332 4.5E-4 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS00920 2754e3cb65a4fea9287bb16e624d0cb8 715 Gene3D G3DSA:2.30.42.10 165 265 8.9E-14 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS00920 2754e3cb65a4fea9287bb16e624d0cb8 715 SMART SM00228 172 262 5.5E-8 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS00920 2754e3cb65a4fea9287bb16e624d0cb8 715 Pfam PF02163 Peptidase family M50 116 699 8.9E-40 T 09-03-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 L21SP3_RS00920 2754e3cb65a4fea9287bb16e624d0cb8 715 Pfam PF02163 Peptidase family M50 39 92 1.7E-10 T 09-03-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 L21SP3_RS00920 2754e3cb65a4fea9287bb16e624d0cb8 715 SUPERFAMILY SSF50156 300 332 4.34E-5 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS00920 2754e3cb65a4fea9287bb16e624d0cb8 715 SUPERFAMILY SSF50156 170 264 7.89E-11 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS00920 2754e3cb65a4fea9287bb16e624d0cb8 715 SUPERFAMILY SSF50156 411 482 3.37E-5 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS00920 2754e3cb65a4fea9287bb16e624d0cb8 715 Gene3D G3DSA:2.30.42.10 412 468 3.1E-6 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS07225 9302508d939f326727dbd8f5d76972ab 1166 Pfam PF02384 N-6 DNA Methylase 357 399 8.2E-5 T 09-03-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 L21SP3_RS07225 9302508d939f326727dbd8f5d76972ab 1166 Gene3D G3DSA:3.40.50.150 434 687 4.1E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS07225 9302508d939f326727dbd8f5d76972ab 1166 Gene3D G3DSA:3.40.50.150 381 398 4.1E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS07225 9302508d939f326727dbd8f5d76972ab 1166 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 379 395 6.8E-11 T 09-03-2017 L21SP3_RS07225 9302508d939f326727dbd8f5d76972ab 1166 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 440 454 6.8E-11 T 09-03-2017 L21SP3_RS07225 9302508d939f326727dbd8f5d76972ab 1166 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 569 581 6.8E-11 T 09-03-2017 L21SP3_RS07225 9302508d939f326727dbd8f5d76972ab 1166 SUPERFAMILY SSF53335 433 737 1.11E-32 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS07225 9302508d939f326727dbd8f5d76972ab 1166 SUPERFAMILY SSF53335 294 398 1.11E-32 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS03595 7ffa88bd206caf0903e321e6d67dacc7 441 SUPERFAMILY SSF55347 171 342 2.83E-21 T 09-03-2017 L21SP3_RS03595 7ffa88bd206caf0903e321e6d67dacc7 441 SUPERFAMILY SSF51735 31 194 1.79E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS03595 7ffa88bd206caf0903e321e6d67dacc7 441 Gene3D G3DSA:3.40.50.720 33 174 3.7E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS03595 7ffa88bd206caf0903e321e6d67dacc7 441 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 63 161 1.2E-11 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP3_RS03595 7ffa88bd206caf0903e321e6d67dacc7 441 Gene3D G3DSA:3.30.360.10 175 409 3.8E-25 T 09-03-2017 L21SP3_RS03595 7ffa88bd206caf0903e321e6d67dacc7 441 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 231 303 2.3E-4 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 L21SP3_RS01570 b43c8261b89a44cb7677693ba21b0da6 304 SUPERFAMILY SSF53335 23 300 9.21E-59 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS01570 b43c8261b89a44cb7677693ba21b0da6 304 Gene3D G3DSA:1.10.8.100 229 297 1.7E-10 T 09-03-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 L21SP3_RS01570 b43c8261b89a44cb7677693ba21b0da6 304 Gene3D G3DSA:3.40.50.150 10 222 1.2E-58 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS01570 b43c8261b89a44cb7677693ba21b0da6 304 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 24 298 41.357 T 09-03-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 L21SP3_RS01570 b43c8261b89a44cb7677693ba21b0da6 304 Pfam PF00398 Ribosomal RNA adenine dimethylase 27 253 2.3E-46 T 09-03-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm L21SP3_RS01570 b43c8261b89a44cb7677693ba21b0da6 304 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 56 83 - T 09-03-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 L21SP3_RS01570 b43c8261b89a44cb7677693ba21b0da6 304 SMART SM00650 40 223 2.6E-53 T 09-03-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 L21SP3_RS01570 b43c8261b89a44cb7677693ba21b0da6 304 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 25 296 8.0E-64 T 09-03-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 L21SP3_RS06265 52578cc2ec18f2c921502eef3c5bd132 999 Gene3D G3DSA:1.10.150.280 822 856 7.8E-4 T 09-03-2017 L21SP3_RS06265 52578cc2ec18f2c921502eef3c5bd132 999 SUPERFAMILY SSF47781 822 859 8.15E-8 T 09-03-2017 IPR010994 RuvA domain 2-like L21SP3_RS03185 fcaa7c9b8877ffa6d8feec9af3a2015b 418 Gene3D G3DSA:2.30.40.10 330 402 3.1E-6 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP3_RS03185 fcaa7c9b8877ffa6d8feec9af3a2015b 418 SUPERFAMILY SSF51338 323 416 6.61E-21 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP3_RS03185 fcaa7c9b8877ffa6d8feec9af3a2015b 418 Gene3D G3DSA:2.30.40.10 16 60 6.8E-6 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP3_RS03185 fcaa7c9b8877ffa6d8feec9af3a2015b 418 Pfam PF01979 Amidohydrolase family 47 391 8.6E-57 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 L21SP3_RS03185 fcaa7c9b8877ffa6d8feec9af3a2015b 418 SUPERFAMILY SSF51338 1 64 9.71E-8 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP3_RS03185 fcaa7c9b8877ffa6d8feec9af3a2015b 418 SUPERFAMILY SSF51556 49 342 2.08E-80 T 09-03-2017 IPR032466 Metal-dependent hydrolase L21SP3_RS03185 fcaa7c9b8877ffa6d8feec9af3a2015b 418 Gene3D G3DSA:3.20.20.140 61 329 3.2E-77 T 09-03-2017 L21SP3_RS06260 30dfd98a1938f4c220e5ea7d72443087 280 Gene3D G3DSA:1.10.510.10 115 260 1.2E-31 T 09-03-2017 L21SP3_RS06260 30dfd98a1938f4c220e5ea7d72443087 280 SMART SM00220 6 268 1.9E-26 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 L21SP3_RS06260 30dfd98a1938f4c220e5ea7d72443087 280 Pfam PF00069 Protein kinase domain 7 260 3.2E-40 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 L21SP3_RS06260 30dfd98a1938f4c220e5ea7d72443087 280 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 126 138 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 L21SP3_RS06260 30dfd98a1938f4c220e5ea7d72443087 280 SUPERFAMILY SSF56112 5 260 8.77E-50 T 09-03-2017 IPR011009 Protein kinase-like domain L21SP3_RS06260 30dfd98a1938f4c220e5ea7d72443087 280 Gene3D G3DSA:3.30.200.20 5 114 6.6E-16 T 09-03-2017 L21SP3_RS00930 70f9ca259deed79a85570c445250b0e1 340 Gene3D G3DSA:3.90.550.10 1 198 7.1E-49 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS00930 70f9ca259deed79a85570c445250b0e1 340 SUPERFAMILY SSF53448 3 211 1.03E-46 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS00930 70f9ca259deed79a85570c445250b0e1 340 Pfam PF00535 Glycosyl transferase family 2 6 138 1.7E-30 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 L21SP3_RS08090 1a61140d9db40d41acda931a73a097d8 342 SUPERFAMILY SSF75005 30 323 1.7E-66 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS08090 1a61140d9db40d41acda931a73a097d8 342 Pfam PF04616 Glycosyl hydrolases family 43 31 323 6.1E-53 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS08090 1a61140d9db40d41acda931a73a097d8 342 Gene3D G3DSA:2.115.10.20 28 333 2.4E-74 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Gene3D G3DSA:3.90.1100.10 590 639 6.7E-121 T 09-03-2017 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Gene3D G3DSA:3.90.1100.10 374 521 6.7E-121 T 09-03-2017 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Gene3D G3DSA:3.90.1100.10 13 140 6.7E-121 T 09-03-2017 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Gene3D G3DSA:2.40.50.150 748 857 2.2E-44 T 09-03-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Gene3D G3DSA:2.40.50.150 976 990 2.2E-44 T 09-03-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Pfam PF04561 RNA polymerase Rpb2, domain 2 271 383 3.7E-21 T 09-03-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 ProSitePatterns PS01166 RNA polymerases beta chain signature. 994 1006 - T 09-03-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Gene3D G3DSA:2.30.150.10 522 587 1.1E-9 T 09-03-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Pfam PF10385 RNA polymerase beta subunit external 1 domain 521 587 4.3E-9 T 09-03-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 SUPERFAMILY SSF64484 970 1245 0.0 T 09-03-2017 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 SUPERFAMILY SSF64484 7 215 0.0 T 09-03-2017 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 SUPERFAMILY SSF64484 272 859 0.0 T 09-03-2017 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Gene3D G3DSA:3.90.1110.10 142 219 8.0E-50 T 09-03-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Gene3D G3DSA:3.90.1110.10 275 373 8.0E-50 T 09-03-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 7 1244 11.387 T 09-03-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 5 1240 0.0 T 09-03-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Pfam PF04563 RNA polymerase beta subunit 21 429 1.0E-19 T 09-03-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Gene3D G3DSA:2.40.50.100 645 713 2.8E-20 T 09-03-2017 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Gene3D G3DSA:2.40.270.10 714 740 1.4E-74 T 09-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Gene3D G3DSA:2.40.270.10 991 1144 1.4E-74 T 09-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Pfam PF00562 RNA polymerase Rpb2, domain 6 649 1166 4.8E-144 T 09-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Pfam PF04565 RNA polymerase Rpb2, domain 3 443 509 2.4E-26 T 09-03-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10790 607c8442678b506f1ae6e07a8a142d53 1251 Pfam PF04560 RNA polymerase Rpb2, domain 7 1168 1242 3.4E-23 T 09-03-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10690 906e2c5303f5bd3357e983e21283145b 546 SUPERFAMILY SSF49899 268 499 4.96E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10690 906e2c5303f5bd3357e983e21283145b 546 SUPERFAMILY SSF48726 179 264 1.86E-12 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS10690 906e2c5303f5bd3357e983e21283145b 546 Pfam PF13927 Immunoglobulin domain 182 256 3.4E-9 T 09-03-2017 L21SP3_RS10690 906e2c5303f5bd3357e983e21283145b 546 SMART SM00409 186 268 1.4E-6 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS10690 906e2c5303f5bd3357e983e21283145b 546 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 349 494 1.8E-16 T 09-03-2017 L21SP3_RS10690 906e2c5303f5bd3357e983e21283145b 546 Gene3D G3DSA:2.60.120.200 274 499 1.0E-22 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10690 906e2c5303f5bd3357e983e21283145b 546 Gene3D G3DSA:2.60.40.10 181 265 3.5E-11 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS03625 0bcbce5a9fa2fe0f39b360e91d07c474 288 Gene3D G3DSA:1.10.3210.10 7 168 1.4E-20 T 09-03-2017 IPR006674 HD domain L21SP3_RS03625 0bcbce5a9fa2fe0f39b360e91d07c474 288 Pfam PF01966 HD domain 36 152 1.4E-14 T 09-03-2017 IPR006674 HD domain L21SP3_RS03625 0bcbce5a9fa2fe0f39b360e91d07c474 288 TIGRFAM TIGR00277 HDIG: HDIG domain 37 104 2.3E-7 T 09-03-2017 IPR006675 HDIG domain L21SP3_RS03625 0bcbce5a9fa2fe0f39b360e91d07c474 288 SMART SM00471 28 163 4.2E-4 T 09-03-2017 IPR003607 HD/PDEase domain L21SP3_RS03625 0bcbce5a9fa2fe0f39b360e91d07c474 288 SUPERFAMILY SSF109604 10 161 3.14E-20 T 09-03-2017 L21SP3_RS02320 f0cf877563e736a026b4b758ff73a300 73 Pfam PF00005 ABC transporter 19 61 9.2E-10 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS02320 f0cf877563e736a026b4b758ff73a300 73 SUPERFAMILY SSF52540 2 63 2.61E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02320 f0cf877563e736a026b4b758ff73a300 73 Gene3D G3DSA:3.40.50.300 1 69 2.2E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05985 2361df2f1b1afe0e79474699af855abd 1134 Gene3D G3DSA:3.30.379.10 44 169 7.4E-19 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS05985 2361df2f1b1afe0e79474699af855abd 1134 Pfam PF15979 Glycosyl hydrolase family 115 186 528 1.0E-123 T 09-03-2017 IPR031924 Glycosyl hydrolase family 115 L21SP3_RS05985 2361df2f1b1afe0e79474699af855abd 1134 SUPERFAMILY SSF55545 48 169 5.93E-9 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS02555 37ff4ad510bb3e486298a32e6411f906 461 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 278 435 2.5E-21 T 09-03-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 L21SP3_RS02555 37ff4ad510bb3e486298a32e6411f906 461 SUPERFAMILY SSF102735 12 142 2.88E-30 T 09-03-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 L21SP3_RS02555 37ff4ad510bb3e486298a32e6411f906 461 Gene3D G3DSA:3.30.70.1050 12 130 2.1E-28 T 09-03-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 L21SP3_RS02555 37ff4ad510bb3e486298a32e6411f906 461 Hamap MF_00303 Trigger factor [tig]. 11 442 16.88 T 09-03-2017 IPR005215 Trigger factor GO:0015031 L21SP3_RS02555 37ff4ad510bb3e486298a32e6411f906 461 SUPERFAMILY SSF109998 266 446 8.37E-32 T 09-03-2017 IPR027304 Trigger factor/SurA domain L21SP3_RS02555 37ff4ad510bb3e486298a32e6411f906 461 TIGRFAM TIGR00115 tig: trigger factor 22 433 3.9E-89 T 09-03-2017 IPR005215 Trigger factor GO:0015031 L21SP3_RS02555 37ff4ad510bb3e486298a32e6411f906 461 Pfam PF05697 Bacterial trigger factor protein (TF) 12 156 6.1E-34 T 09-03-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 L21SP3_RS02555 37ff4ad510bb3e486298a32e6411f906 461 Gene3D G3DSA:1.10.3120.10 222 409 1.2E-35 T 09-03-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 L21SP3_RS02555 37ff4ad510bb3e486298a32e6411f906 461 SUPERFAMILY SSF54534 145 264 2.42E-10 T 09-03-2017 L21SP3_RS02555 37ff4ad510bb3e486298a32e6411f906 461 PIRSF PIRSF003095 11 457 2.8E-79 T 09-03-2017 IPR005215 Trigger factor GO:0015031 L21SP3_RS05385 b61dfac353418efefcb133d0181e3a71 255 Pfam PF02237 Biotin protein ligase C terminal domain 215 251 2.5E-7 T 09-03-2017 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 L21SP3_RS05385 b61dfac353418efefcb133d0181e3a71 255 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 15 252 5.2E-55 T 09-03-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 L21SP3_RS05385 b61dfac353418efefcb133d0181e3a71 255 Gene3D G3DSA:3.30.930.10 10 203 3.6E-56 T 09-03-2017 L21SP3_RS05385 b61dfac353418efefcb133d0181e3a71 255 Gene3D G3DSA:2.30.30.100 213 251 9.3E-6 T 09-03-2017 L21SP3_RS05385 b61dfac353418efefcb133d0181e3a71 255 Pfam PF03099 Biotin/lipoate A/B protein ligase family 18 142 2.7E-17 T 09-03-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 L21SP3_RS05385 b61dfac353418efefcb133d0181e3a71 255 SUPERFAMILY SSF55681 13 204 2.05E-50 T 09-03-2017 L21SP3_RS02055 674ed9d2953beff723c1eb6c14e1140c 121 SUPERFAMILY SSF75620 21 104 1.31E-20 T 09-03-2017 L21SP3_RS02055 674ed9d2953beff723c1eb6c14e1140c 121 Gene3D G3DSA:3.30.160.20 21 94 5.4E-24 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain L21SP3_RS02055 674ed9d2953beff723c1eb6c14e1140c 121 Pfam PF00472 RF-1 domain 21 114 3.2E-22 T 09-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 SUPERFAMILY SSF52954 377 481 5.13E-32 T 09-03-2017 IPR004154 Anticodon-binding L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 Gene3D G3DSA:3.30.930.10 9 92 2.3E-139 T 09-03-2017 L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 Gene3D G3DSA:3.30.930.10 125 385 2.3E-139 T 09-03-2017 L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 Gene3D G3DSA:3.40.50.800 386 481 1.1E-38 T 09-03-2017 IPR004154 Anticodon-binding L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 7 239 1.9E-83 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 155 358 1.4E-11 T 09-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 9.3E-53 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 PRINTS PR01043 Glycyl-tRNA synthetase signature 427 446 9.3E-53 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 9.3E-53 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 9.3E-53 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 PRINTS PR01043 Glycyl-tRNA synthetase signature 26 40 9.3E-53 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 PRINTS PR01043 Glycyl-tRNA synthetase signature 140 152 9.3E-53 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 PRINTS PR01043 Glycyl-tRNA synthetase signature 346 358 9.3E-53 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 Pfam PF03129 Anticodon binding domain 390 477 2.3E-17 T 09-03-2017 IPR004154 Anticodon-binding L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 SUPERFAMILY SSF55681 6 393 5.6E-110 T 09-03-2017 L21SP3_RS01370 0457b72c68bbec0048bb79d942779cc7 487 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 4 482 47.829 T 09-03-2017 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 L21SP3_RS01390 d12bf5e75f4fc2cefc4eda983e37e486 338 Gene3D G3DSA:3.30.420.40 254 308 3.1E-25 T 09-03-2017 L21SP3_RS01390 d12bf5e75f4fc2cefc4eda983e37e486 338 Gene3D G3DSA:3.30.420.40 151 177 3.1E-25 T 09-03-2017 L21SP3_RS01390 d12bf5e75f4fc2cefc4eda983e37e486 338 Gene3D G3DSA:3.30.420.40 1 150 1.0E-41 T 09-03-2017 L21SP3_RS01390 d12bf5e75f4fc2cefc4eda983e37e486 338 Gene3D G3DSA:3.90.640.10 178 250 8.9E-31 T 09-03-2017 L21SP3_RS01390 d12bf5e75f4fc2cefc4eda983e37e486 338 Pfam PF06723 MreB/Mbl protein 1 326 4.1E-134 T 09-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP3_RS01390 d12bf5e75f4fc2cefc4eda983e37e486 338 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 1 326 2.6E-138 T 09-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP3_RS01390 d12bf5e75f4fc2cefc4eda983e37e486 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 60 83 1.5E-53 T 09-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP3_RS01390 d12bf5e75f4fc2cefc4eda983e37e486 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 291 317 1.5E-53 T 09-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP3_RS01390 d12bf5e75f4fc2cefc4eda983e37e486 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 40 58 1.5E-53 T 09-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP3_RS01390 d12bf5e75f4fc2cefc4eda983e37e486 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 123 142 1.5E-53 T 09-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP3_RS01390 d12bf5e75f4fc2cefc4eda983e37e486 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 178 198 1.5E-53 T 09-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 L21SP3_RS01390 d12bf5e75f4fc2cefc4eda983e37e486 338 SUPERFAMILY SSF53067 140 323 2.59E-47 T 09-03-2017 L21SP3_RS01390 d12bf5e75f4fc2cefc4eda983e37e486 338 SUPERFAMILY SSF53067 1 139 1.68E-36 T 09-03-2017 L21SP3_RS07385 abf48ec16fdbb6f5cc3b90ed1172fb85 285 Pfam PF00950 ABC 3 transport family 18 267 7.9E-52 T 09-03-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 L21SP3_RS07385 abf48ec16fdbb6f5cc3b90ed1172fb85 285 SUPERFAMILY SSF81345 13 266 1.29E-28 T 09-03-2017 IPR029022 ABC transporter, BtuC-like L21SP3_RS07385 abf48ec16fdbb6f5cc3b90ed1172fb85 285 Gene3D G3DSA:1.10.3470.10 42 266 2.0E-5 T 09-03-2017 IPR029022 ABC transporter, BtuC-like L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 PRINTS PR00132 Glycosyl hydrolase family 2 signature 407 422 9.3E-6 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 PRINTS PR00132 Glycosyl hydrolase family 2 signature 341 359 9.3E-6 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 PRINTS PR00132 Glycosyl hydrolase family 2 signature 110 125 9.3E-6 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 PRINTS PR00132 Glycosyl hydrolase family 2 signature 310 324 9.3E-6 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 SUPERFAMILY SSF51445 301 594 2.08E-52 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 Gene3D G3DSA:3.20.20.80 302 594 2.8E-50 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 SUPERFAMILY SSF49265 688 779 5.39E-5 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 Gene3D G3DSA:2.60.120.260 16 168 3.4E-43 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 Gene3D G3DSA:2.60.40.320 169 300 8.9E-19 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 34 177 7.4E-19 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 SUPERFAMILY SSF49785 32 177 9.96E-41 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 302 594 4.9E-25 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 Gene3D G3DSA:2.60.40.10 696 776 3.7E-4 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 SUPERFAMILY SSF49303 180 299 7.77E-11 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS09335 d8dd53e02c08a6b53906fca172b921a7 871 Pfam PF00703 Glycosyl hydrolases family 2 180 299 8.0E-13 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS09845 7a4c3754ce78a2cf372996420f22c5ae 299 SUPERFAMILY SSF48576 12 281 4.32E-77 T 09-03-2017 IPR008949 Isoprenoid synthase domain L21SP3_RS09845 7a4c3754ce78a2cf372996420f22c5ae 299 Pfam PF00348 Polyprenyl synthetase 36 267 9.4E-56 T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 L21SP3_RS09845 7a4c3754ce78a2cf372996420f22c5ae 299 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 88 104 - T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 L21SP3_RS09845 7a4c3754ce78a2cf372996420f22c5ae 299 Gene3D G3DSA:1.10.600.10 7 289 1.6E-83 T 09-03-2017 IPR008949 Isoprenoid synthase domain L21SP3_RS02515 177ac38cf41dcf5a37b3abe93cd44098 231 SUPERFAMILY SSF54862 5 67 1.5E-17 T 09-03-2017 L21SP3_RS02515 177ac38cf41dcf5a37b3abe93cd44098 231 Pfam PF00037 4Fe-4S binding domain 8 31 5.8E-8 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS02515 177ac38cf41dcf5a37b3abe93cd44098 231 Gene3D G3DSA:3.30.70.20 7 64 9.5E-17 T 09-03-2017 L21SP3_RS11795 5662b8a3baebf823c9d4db1a067028bb 320 Pfam PF02911 Formyl transferase, C-terminal domain 203 303 3.8E-17 T 09-03-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP3_RS11795 5662b8a3baebf823c9d4db1a067028bb 320 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 305 3.8E-75 T 09-03-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 L21SP3_RS11795 5662b8a3baebf823c9d4db1a067028bb 320 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 307 27.647 T 09-03-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 L21SP3_RS11795 5662b8a3baebf823c9d4db1a067028bb 320 Pfam PF00551 Formyl transferase 4 179 5.1E-34 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP3_RS11795 5662b8a3baebf823c9d4db1a067028bb 320 Gene3D G3DSA:3.10.25.10 206 312 3.4E-18 T 09-03-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP3_RS11795 5662b8a3baebf823c9d4db1a067028bb 320 SUPERFAMILY SSF50486 204 305 8.63E-18 T 09-03-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 L21SP3_RS11795 5662b8a3baebf823c9d4db1a067028bb 320 Gene3D G3DSA:3.40.50.170 1 204 1.9E-61 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP3_RS11795 5662b8a3baebf823c9d4db1a067028bb 320 SUPERFAMILY SSF53328 1 206 8.11E-58 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP3_RS07105 19e5bb80be6a2c08c2696638122807e4 459 Pfam PF02397 Bacterial sugar transferase 273 455 6.6E-56 T 09-03-2017 IPR003362 Bacterial sugar transferase L21SP3_RS07105 19e5bb80be6a2c08c2696638122807e4 459 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 21 457 1.3E-97 T 09-03-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase L21SP3_RS04820 d15f1f6f1e0b2822cf0ca6d6e61bc76a 370 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 351 1.2E-179 T 09-03-2017 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 L21SP3_RS04820 d15f1f6f1e0b2822cf0ca6d6e61bc76a 370 Gene3D G3DSA:3.40.50.720 2 190 7.1E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04820 d15f1f6f1e0b2822cf0ca6d6e61bc76a 370 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 344 3.6E-159 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04820 d15f1f6f1e0b2822cf0ca6d6e61bc76a 370 SUPERFAMILY SSF51735 3 350 7.4E-88 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04820 d15f1f6f1e0b2822cf0ca6d6e61bc76a 370 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 354 57.715 T 09-03-2017 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 L21SP3_RS04820 d15f1f6f1e0b2822cf0ca6d6e61bc76a 370 Gene3D G3DSA:3.90.25.10 193 247 4.0E-52 T 09-03-2017 L21SP3_RS04820 d15f1f6f1e0b2822cf0ca6d6e61bc76a 370 Gene3D G3DSA:3.90.25.10 302 359 4.0E-52 T 09-03-2017 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Pfam PF02142 MGS-like domain 954 1039 9.2E-18 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 SMART SM00851 953 1039 1.4E-24 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 SUPERFAMILY SSF48108 396 551 2.09E-46 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 SUPERFAMILY SSF52440 2 127 6.76E-49 T 09-03-2017 IPR016185 Pre-ATP-grasp domain L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Gene3D G3DSA:3.30.1490.20 685 742 1.3E-23 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1067 13.608 T 09-03-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Gene3D G3DSA:3.30.1490.20 141 199 5.8E-20 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1048 0.0 T 09-03-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Gene3D G3DSA:3.40.50.20 3 108 5.1E-43 T 09-03-2017 IPR016185 Pre-ATP-grasp domain L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Gene3D G3DSA:1.10.1030.10 400 537 6.7E-49 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 SUPERFAMILY SSF52335 935 1068 4.58E-34 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 SUPERFAMILY SSF52440 554 673 1.38E-49 T 09-03-2017 IPR016185 Pre-ATP-grasp domain L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Gene3D G3DSA:3.30.470.20 743 931 1.1E-71 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Gene3D G3DSA:3.30.470.20 200 399 2.1E-77 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 707 721 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Gene3D G3DSA:3.40.50.1380 935 1068 2.6E-37 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 SMART SM01096 422 545 4.0E-59 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 545 1.2E-39 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1060 12.796 T 09-03-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Gene3D G3DSA:3.40.50.20 538 660 2.9E-61 T 09-03-2017 IPR016185 Pre-ATP-grasp domain L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.3E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.3E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.3E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.3E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 3.3E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.3E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 3.3E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 129 334 1.3E-68 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 671 873 2.4E-38 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 836 843 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 SUPERFAMILY SSF56059 129 400 2.47E-106 T 09-03-2017 L21SP3_RS00455 6845848c9403dd156ebadc2290bf1e0a 1071 SUPERFAMILY SSF56059 671 931 3.71E-98 T 09-03-2017 L21SP3_RS10300 0727d862fcfbac9d99c0ea1b2f338391 304 Pfam PF01609 Transposase DDE domain 72 201 2.8E-10 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS05440 a6b689873b9063d51c65c7ef49fe4b68 308 Gene3D G3DSA:3.40.190.10 51 136 3.7E-27 T 09-03-2017 L21SP3_RS05440 a6b689873b9063d51c65c7ef49fe4b68 308 SUPERFAMILY SSF53850 51 307 6.25E-77 T 09-03-2017 L21SP3_RS05440 a6b689873b9063d51c65c7ef49fe4b68 308 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 56 299 3.0E-64 T 09-03-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 L21SP3_RS05440 a6b689873b9063d51c65c7ef49fe4b68 308 Gene3D G3DSA:3.40.190.100 138 259 1.2E-39 T 09-03-2017 L21SP3_RS04495 a90e6bbbb3d6c9a2f79b519c55775dda 329 Pfam PF10503 Esterase PHB depolymerase 57 190 1.0E-9 T 09-03-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 L21SP3_RS04495 a90e6bbbb3d6c9a2f79b519c55775dda 329 Gene3D G3DSA:3.40.50.1820 35 328 6.2E-35 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS04495 a90e6bbbb3d6c9a2f79b519c55775dda 329 SUPERFAMILY SSF53474 46 222 1.95E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS04495 a90e6bbbb3d6c9a2f79b519c55775dda 329 SUPERFAMILY SSF53474 270 320 1.95E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS00180 9835b6876759ba831a2b7e82140a82eb 665 Pfam PF09822 ABC-type uncharacterized transport system 33 312 5.1E-59 T 09-03-2017 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 L21SP3_RS00670 6dcb233236365f89d7a78eac6ce1d1fb 215 Pfam PF00072 Response regulator receiver domain 11 120 7.2E-28 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS00670 6dcb233236365f89d7a78eac6ce1d1fb 215 SUPERFAMILY SSF46894 147 212 6.12E-19 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 L21SP3_RS00670 6dcb233236365f89d7a78eac6ce1d1fb 215 SUPERFAMILY SSF52172 8 136 5.69E-32 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS00670 6dcb233236365f89d7a78eac6ce1d1fb 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 2.8E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 L21SP3_RS00670 6dcb233236365f89d7a78eac6ce1d1fb 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 2.8E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 L21SP3_RS00670 6dcb233236365f89d7a78eac6ce1d1fb 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 2.8E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 L21SP3_RS00670 6dcb233236365f89d7a78eac6ce1d1fb 215 Gene3D G3DSA:3.40.50.2300 6 157 3.8E-34 T 09-03-2017 L21SP3_RS00670 6dcb233236365f89d7a78eac6ce1d1fb 215 SMART SM00421 150 207 1.6E-19 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 L21SP3_RS00670 6dcb233236365f89d7a78eac6ce1d1fb 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 1.5E-18 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 L21SP3_RS00670 6dcb233236365f89d7a78eac6ce1d1fb 215 Gene3D G3DSA:1.10.10.10 158 212 2.1E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS00670 6dcb233236365f89d7a78eac6ce1d1fb 215 SMART SM00448 9 120 9.0E-33 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS03400 a6a2533c2c9484caa72a70b095ab8b55 376 SUPERFAMILY SSF51445 348 361 2.05E-45 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS03400 a6a2533c2c9484caa72a70b095ab8b55 376 SUPERFAMILY SSF51445 36 320 2.05E-45 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS03400 a6a2533c2c9484caa72a70b095ab8b55 376 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 58 306 6.9E-9 T 09-03-2017 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 L21SP3_RS03400 a6a2533c2c9484caa72a70b095ab8b55 376 Gene3D G3DSA:3.20.20.80 37 353 3.0E-62 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS10515 19813fea72851b1623b9e177821db1bb 275 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 30 260 3.6E-32 T 09-03-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 L21SP3_RS10515 19813fea72851b1623b9e177821db1bb 275 Gene3D G3DSA:3.20.20.190 7 266 2.6E-63 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 L21SP3_RS10515 19813fea72851b1623b9e177821db1bb 275 SUPERFAMILY SSF51695 25 261 1.62E-63 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 L21SP3_RS00370 15a5582e6347c3d48db249d0f85d95cd 427 Gene3D G3DSA:2.115.10.20 14 328 6.7E-94 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS00370 15a5582e6347c3d48db249d0f85d95cd 427 SUPERFAMILY SSF75005 27 327 2.57E-82 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS00370 15a5582e6347c3d48db249d0f85d95cd 427 Pfam PF04616 Glycosyl hydrolases family 43 27 325 5.5E-56 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS01600 d1f419987d74620f8700441c1e54f22e 424 Gene3D G3DSA:3.20.20.210 127 128 2.3E-39 T 09-03-2017 L21SP3_RS01600 d1f419987d74620f8700441c1e54f22e 424 Gene3D G3DSA:3.20.20.210 1 80 2.3E-39 T 09-03-2017 L21SP3_RS01600 d1f419987d74620f8700441c1e54f22e 424 Gene3D G3DSA:3.20.20.210 163 417 2.3E-39 T 09-03-2017 L21SP3_RS01600 d1f419987d74620f8700441c1e54f22e 424 SUPERFAMILY SSF51726 118 419 9.07E-32 T 09-03-2017 L21SP3_RS01600 d1f419987d74620f8700441c1e54f22e 424 SUPERFAMILY SSF51726 1 79 9.07E-32 T 09-03-2017 L21SP3_RS01600 d1f419987d74620f8700441c1e54f22e 424 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 223 416 1.5E-20 T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 Gene3D G3DSA:3.30.70.20 488 513 3.7E-5 T 09-03-2017 L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 Gene3D G3DSA:3.30.70.20 565 587 3.7E-5 T 09-03-2017 L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 SUPERFAMILY SSF54862 575 628 2.29E-17 T 09-03-2017 L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 583 594 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 SUPERFAMILY SSF140490 471 571 1.1E-36 T 09-03-2017 L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 22 108 2.0E-9 T 09-03-2017 L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 Gene3D G3DSA:3.40.30.10 22 128 2.7E-26 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 476 559 5.1E-32 T 09-03-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 SMART SM00928 474 519 1.7E-21 T 09-03-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 487 498 - T 09-03-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 Pfam PF00037 4Fe-4S binding domain 607 628 9.4E-8 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 Pfam PF00037 4Fe-4S binding domain 576 599 3.6E-9 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 SUPERFAMILY SSF142984 380 469 2.09E-22 T 09-03-2017 L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 SUPERFAMILY SSF142019 138 379 1.96E-89 T 09-03-2017 L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 Gene3D G3DSA:3.30.70.20 588 628 6.8E-16 T 09-03-2017 L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 SUPERFAMILY SSF52833 23 124 7.16E-21 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS06445 4d2a71dc7720655559c9592aa53f71f2 631 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 188 358 4.9E-48 T 09-03-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 SUPERFAMILY SSF50447 208 304 2.75E-29 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 SUPERFAMILY SSF50465 301 401 1.49E-33 T 09-03-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 4.9E-60 T 09-03-2017 L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 Pfam PF03143 Elongation factor Tu C-terminal domain 301 400 1.6E-34 T 09-03-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 PRINTS PR00315 GTP-binding elongation factor signature 58 66 5.8E-25 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 PRINTS PR00315 GTP-binding elongation factor signature 94 105 5.8E-25 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 PRINTS PR00315 GTP-binding elongation factor signature 78 88 5.8E-25 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 PRINTS PR00315 GTP-binding elongation factor signature 14 27 5.8E-25 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 PRINTS PR00315 GTP-binding elongation factor signature 131 140 5.8E-25 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 Pfam PF03144 Elongation factor Tu domain 2 228 296 1.9E-16 T 09-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 402 58.757 T 09-03-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 Gene3D G3DSA:2.40.30.10 215 300 1.9E-34 T 09-03-2017 L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 SUPERFAMILY SSF52540 9 229 1.61E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 402 7.5E-213 T 09-03-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 09-03-2017 IPR031157 Tr-type G domain, conserved site L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 Gene3D G3DSA:2.40.30.10 303 401 5.2E-43 T 09-03-2017 L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 151 2.2E-15 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP3_RS10745 98f3c96399dfdfbfe4200f2049d1b4ee 402 Gene3D G3DSA:3.40.50.300 6 214 8.2E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02980 8ea31d085ab0020df343e7d6638d6423 151 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 9.6E-49 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 L21SP3_RS02980 8ea31d085ab0020df343e7d6638d6423 151 SUPERFAMILY SSF89623 1 144 2.88E-51 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 L21SP3_RS02980 8ea31d085ab0020df343e7d6638d6423 151 PIRSF PIRSF005384 1 147 1.4E-52 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 L21SP3_RS02980 8ea31d085ab0020df343e7d6638d6423 151 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 3 144 1.9E-43 T 09-03-2017 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 L21SP3_RS02980 8ea31d085ab0020df343e7d6638d6423 151 Gene3D G3DSA:3.40.1400.10 1 146 1.1E-53 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 L21SP3_RS02980 8ea31d085ab0020df343e7d6638d6423 151 Pfam PF02502 Ribose/Galactose Isomerase 3 140 5.6E-49 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 L21SP3_RS11285 50db5fe2fdbd3ac89c20e9a6f2161297 181 Pfam PF02417 Chromate transporter 5 178 4.4E-42 T 09-03-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 L21SP3_RS05190 68609ef19f303537939c932121d035e7 358 PIRSF PIRSF000530 3 329 1.2E-39 T 09-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 L21SP3_RS05190 68609ef19f303537939c932121d035e7 358 Pfam PF00288 GHMP kinases N terminal domain 110 175 1.6E-4 T 09-03-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 L21SP3_RS05190 68609ef19f303537939c932121d035e7 358 SUPERFAMILY SSF55060 203 322 6.33E-11 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain L21SP3_RS05190 68609ef19f303537939c932121d035e7 358 Gene3D G3DSA:3.30.230.10 16 206 2.4E-31 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup L21SP3_RS05190 68609ef19f303537939c932121d035e7 358 PRINTS PR00959 Mevalonate kinase family signature 157 176 1.1E-5 T 09-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 L21SP3_RS05190 68609ef19f303537939c932121d035e7 358 PRINTS PR00959 Mevalonate kinase family signature 17 41 1.1E-5 T 09-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 L21SP3_RS05190 68609ef19f303537939c932121d035e7 358 PRINTS PR00959 Mevalonate kinase family signature 113 135 1.1E-5 T 09-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 L21SP3_RS05190 68609ef19f303537939c932121d035e7 358 Gene3D G3DSA:3.30.70.890 207 322 6.8E-12 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain L21SP3_RS05190 68609ef19f303537939c932121d035e7 358 SUPERFAMILY SSF54211 15 196 1.04E-24 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS02970 e6beaff2bcca0090fe8933fa3f76bdf1 290 SUPERFAMILY SSF56300 57 284 1.82E-27 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS02970 e6beaff2bcca0090fe8933fa3f76bdf1 290 Pfam PF00149 Calcineurin-like phosphoesterase 61 224 2.1E-9 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 L21SP3_RS02970 e6beaff2bcca0090fe8933fa3f76bdf1 290 Gene3D G3DSA:3.60.21.10 61 265 2.7E-17 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS09060 19b9ae53e182536706d4f850d238d10c 364 Gene3D G3DSA:3.40.50.2000 198 359 8.5E-47 T 09-03-2017 L21SP3_RS09060 19b9ae53e182536706d4f850d238d10c 364 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 26 357 6.3E-100 T 09-03-2017 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 L21SP3_RS09060 19b9ae53e182536706d4f850d238d10c 364 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 359 1.5E-95 T 09-03-2017 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 L21SP3_RS09060 19b9ae53e182536706d4f850d238d10c 364 SUPERFAMILY SSF53756 1 361 4.52E-102 T 09-03-2017 L21SP3_RS09060 19b9ae53e182536706d4f850d238d10c 364 Gene3D G3DSA:3.40.50.2000 1 197 7.1E-73 T 09-03-2017 L21SP3_RS02590 aaef351ad6fa6381c8d074b752bff6a1 260 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 6 256 3.5E-78 T 09-03-2017 L21SP3_RS02590 aaef351ad6fa6381c8d074b752bff6a1 260 SUPERFAMILY SSF52317 2 256 1.1E-69 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS02590 aaef351ad6fa6381c8d074b752bff6a1 260 PIRSF PIRSF001586 2 259 4.7E-78 T 09-03-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 L21SP3_RS02590 aaef351ad6fa6381c8d074b752bff6a1 260 Gene3D G3DSA:3.40.50.880 7 257 2.2E-22 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS02590 aaef351ad6fa6381c8d074b752bff6a1 260 SMART SM01211 4 256 2.2E-99 T 09-03-2017 L21SP3_RS02590 aaef351ad6fa6381c8d074b752bff6a1 260 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 8 253 1.4E-57 T 09-03-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 L21SP3_RS02790 89f85c93ce535259e75f09a166b77586 319 Gene3D G3DSA:2.115.10.20 34 297 8.6E-47 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS02790 89f85c93ce535259e75f09a166b77586 319 Pfam PF04616 Glycosyl hydrolases family 43 34 297 4.2E-33 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS02790 89f85c93ce535259e75f09a166b77586 319 SUPERFAMILY SSF75005 33 306 6.28E-42 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS04075 d4f7a930bf4d22e75a2709256f0394a2 473 ProSitePatterns PS00523 Sulfatases signature 1. 90 102 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS04075 d4f7a930bf4d22e75a2709256f0394a2 473 Gene3D G3DSA:3.40.720.10 42 395 4.9E-112 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS04075 d4f7a930bf4d22e75a2709256f0394a2 473 SUPERFAMILY SSF53649 42 451 3.78E-127 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS04075 d4f7a930bf4d22e75a2709256f0394a2 473 Gene3D G3DSA:3.30.1120.10 396 456 5.3E-21 T 09-03-2017 L21SP3_RS04075 d4f7a930bf4d22e75a2709256f0394a2 473 Pfam PF00884 Sulfatase 44 359 4.2E-77 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS11255 527539f0310fd9283fcc4c02516e18d1 263 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 39 261 1.1E-37 T 09-03-2017 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system L21SP3_RS07690 2bdca5bba2f29e7dd3252de9423ecb33 190 Gene3D G3DSA:2.20.28.10 146 190 3.2E-16 T 09-03-2017 IPR004039 Rubredoxin-type fold L21SP3_RS07690 2bdca5bba2f29e7dd3252de9423ecb33 190 Gene3D G3DSA:1.20.1260.10 1 144 6.8E-57 T 09-03-2017 IPR012347 Ferritin-related L21SP3_RS07690 2bdca5bba2f29e7dd3252de9423ecb33 190 SUPERFAMILY SSF57802 149 189 7.61E-11 T 09-03-2017 L21SP3_RS07690 2bdca5bba2f29e7dd3252de9423ecb33 190 SUPERFAMILY SSF47240 3 146 4.84E-41 T 09-03-2017 IPR009078 Ferritin-like superfamily L21SP3_RS07690 2bdca5bba2f29e7dd3252de9423ecb33 190 Pfam PF02915 Rubrerythrin 11 137 1.4E-33 T 09-03-2017 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 L21SP3_RS05425 37dcfc4423b4f07d82fc4b1a86e1f3d1 209 ProSitePatterns PS00018 EF-hand calcium-binding domain. 160 172 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS05425 37dcfc4423b4f07d82fc4b1a86e1f3d1 209 ProSitePatterns PS00018 EF-hand calcium-binding domain. 188 200 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS05425 37dcfc4423b4f07d82fc4b1a86e1f3d1 209 Gene3D G3DSA:1.10.1330.10 156 205 4.0E-8 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS05425 37dcfc4423b4f07d82fc4b1a86e1f3d1 209 SUPERFAMILY SSF63446 162 207 3.27E-7 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS10365 181e801e2cb8ca29bb2f74a9a47dc616 755 Gene3D G3DSA:2.120.10.30 387 470 8.3E-6 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like L21SP3_RS10365 181e801e2cb8ca29bb2f74a9a47dc616 755 SUPERFAMILY SSF50939 42 169 2.0E-9 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS10365 181e801e2cb8ca29bb2f74a9a47dc616 755 Gene3D G3DSA:2.120.10.10 48 173 6.1E-14 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS05905 3347198596464c7749fd11405342582a 586 SUPERFAMILY SSF53098 163 579 9.1E-11 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS05905 3347198596464c7749fd11405342582a 586 Pfam PF01609 Transposase DDE domain 208 506 9.8E-19 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS04610 3347198596464c7749fd11405342582a 586 SUPERFAMILY SSF53098 163 579 9.1E-11 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS04610 3347198596464c7749fd11405342582a 586 Pfam PF01609 Transposase DDE domain 208 506 9.8E-19 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS11205 a395f5b2fc2ac566cc72360efada3fa2 491 ProSitePatterns PS00523 Sulfatases signature 1. 79 91 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS11205 a395f5b2fc2ac566cc72360efada3fa2 491 ProSitePatterns PS00149 Sulfatases signature 2. 147 157 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS11205 a395f5b2fc2ac566cc72360efada3fa2 491 Gene3D G3DSA:3.40.720.10 30 400 1.4E-117 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS11205 a395f5b2fc2ac566cc72360efada3fa2 491 SUPERFAMILY SSF53649 31 478 6.41E-135 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS11205 a395f5b2fc2ac566cc72360efada3fa2 491 Gene3D G3DSA:3.30.1120.10 402 482 3.6E-20 T 09-03-2017 L21SP3_RS11205 a395f5b2fc2ac566cc72360efada3fa2 491 Pfam PF00884 Sulfatase 33 378 2.8E-76 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS11205 a395f5b2fc2ac566cc72360efada3fa2 491 Pfam PF16347 Domain of unknown function (DUF4976) 386 472 1.2E-9 T 09-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 L21SP3_RS01715 cc74f6cd1a0b2c98bcf8e6c019aad29a 334 SUPERFAMILY SSF51735 3 173 9.44E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS01715 cc74f6cd1a0b2c98bcf8e6c019aad29a 334 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 120 1.3E-26 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP3_RS01715 cc74f6cd1a0b2c98bcf8e6c019aad29a 334 SUPERFAMILY SSF55347 139 239 9.37E-14 T 09-03-2017 L21SP3_RS01715 cc74f6cd1a0b2c98bcf8e6c019aad29a 334 Gene3D G3DSA:3.40.50.720 1 128 8.9E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS01715 cc74f6cd1a0b2c98bcf8e6c019aad29a 334 Gene3D G3DSA:3.30.360.10 129 332 5.2E-24 T 09-03-2017 L21SP3_RS02375 96f238785605a8cae3ae6e45ed5d7567 339 SUPERFAMILY SSF103486 20 337 4.58E-29 T 09-03-2017 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS02375 96f238785605a8cae3ae6e45ed5d7567 339 Pfam PF01992 ATP synthase (C/AC39) subunit 25 335 1.1E-30 T 09-03-2017 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS09460 117975d82a60ddcd0288a25d32966e0d 769 Gene3D G3DSA:3.40.50.620 487 620 1.6E-9 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS09460 117975d82a60ddcd0288a25d32966e0d 769 Gene3D G3DSA:3.40.50.620 621 755 5.3E-9 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS09460 117975d82a60ddcd0288a25d32966e0d 769 SUPERFAMILY SSF52402 634 755 3.25E-8 T 09-03-2017 L21SP3_RS09460 117975d82a60ddcd0288a25d32966e0d 769 SUPERFAMILY SSF52402 501 627 5.53E-9 T 09-03-2017 L21SP3_RS09460 117975d82a60ddcd0288a25d32966e0d 769 Pfam PF13520 Amino acid permease 19 453 1.1E-44 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 L21SP3_RS09460 117975d82a60ddcd0288a25d32966e0d 769 Pfam PF00582 Universal stress protein family 558 626 1.9E-7 T 09-03-2017 IPR006016 UspA GO:0006950 L21SP3_RS04480 8aef48a554c51354489448cd8b4d1683 879 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 651 831 1.5E-10 T 09-03-2017 L21SP3_RS04480 8aef48a554c51354489448cd8b4d1683 879 SUPERFAMILY SSF49899 580 834 5.76E-19 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04480 8aef48a554c51354489448cd8b4d1683 879 SMART SM00409 505 580 3.7E-9 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS04480 8aef48a554c51354489448cd8b4d1683 879 Gene3D G3DSA:2.60.40.10 503 580 3.1E-16 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS04480 8aef48a554c51354489448cd8b4d1683 879 SMART SM00408 511 569 6.8E-4 T 09-03-2017 IPR003598 Immunoglobulin subtype 2 L21SP3_RS04480 8aef48a554c51354489448cd8b4d1683 879 Gene3D G3DSA:2.60.120.200 581 834 4.8E-18 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04480 8aef48a554c51354489448cd8b4d1683 879 Pfam PF13927 Immunoglobulin domain 508 566 1.5E-8 T 09-03-2017 L21SP3_RS04480 8aef48a554c51354489448cd8b4d1683 879 SUPERFAMILY SSF48726 497 580 1.39E-15 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 Gene3D G3DSA:1.10.560.10 364 519 1.7E-39 T 09-03-2017 IPR027413 GroEL-like equatorial domain L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 Gene3D G3DSA:3.50.7.10 189 363 1.2E-93 T 09-03-2017 IPR027409 GroEL-like apical domain L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 Hamap MF_00600 60 kDa chaperonin [groL]. 2 548 37.232 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 SUPERFAMILY SSF52029 186 378 2.39E-78 T 09-03-2017 IPR027409 GroEL-like apical domain L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 Gene3D G3DSA:1.10.560.10 3 188 4.7E-45 T 09-03-2017 IPR027413 GroEL-like equatorial domain L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 SUPERFAMILY SSF54849 140 206 3.2E-21 T 09-03-2017 L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 SUPERFAMILY SSF48592 411 522 4.58E-71 T 09-03-2017 L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 SUPERFAMILY SSF48592 11 138 4.58E-71 T 09-03-2017 L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 PRINTS PR00298 60kDa chaperonin signature 83 110 1.2E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 PRINTS PR00298 60kDa chaperonin signature 27 53 1.2E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 PRINTS PR00298 60kDa chaperonin signature 352 377 1.2E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 PRINTS PR00298 60kDa chaperonin signature 270 293 1.2E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 PRINTS PR00298 60kDa chaperonin signature 400 421 1.2E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 524 3.6E-93 T 09-03-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 L21SP3_RS06910 49edf7535491f27ee82a41eb76556792 566 TIGRFAM TIGR02348 GroEL: chaperonin GroL 4 527 3.6E-227 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS07395 0cb99e497c2361cfddcaecf87ee9ac8e 482 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 8 455 2.7E-146 T 09-03-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 L21SP3_RS07395 0cb99e497c2361cfddcaecf87ee9ac8e 482 Pfam PF00156 Phosphoribosyl transferase domain 285 389 1.2E-7 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 L21SP3_RS07395 0cb99e497c2361cfddcaecf87ee9ac8e 482 SUPERFAMILY SSF53271 249 461 5.38E-66 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like L21SP3_RS07395 0cb99e497c2361cfddcaecf87ee9ac8e 482 SUPERFAMILY SSF56235 8 237 1.12E-60 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP3_RS07395 0cb99e497c2361cfddcaecf87ee9ac8e 482 Pfam PF13537 Glutamine amidotransferase domain 90 211 1.2E-22 T 09-03-2017 IPR017932 Glutamine amidotransferase type 2 domain L21SP3_RS07395 0cb99e497c2361cfddcaecf87ee9ac8e 482 Gene3D G3DSA:3.60.20.10 8 257 6.7E-60 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP3_RS07395 0cb99e497c2361cfddcaecf87ee9ac8e 482 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 7 457 43.783 T 09-03-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 L21SP3_RS07395 0cb99e497c2361cfddcaecf87ee9ac8e 482 PIRSF PIRSF000485 4 471 3.0E-162 T 09-03-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 L21SP3_RS07395 0cb99e497c2361cfddcaecf87ee9ac8e 482 Gene3D G3DSA:3.40.50.2020 272 436 6.0E-40 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like L21SP3_RS06145 287adc0a3e59d71cb54f1d85286ebbd2 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 23.809 T 09-03-2017 IPR023053 Ribosomal protein S14, type Z L21SP3_RS06145 287adc0a3e59d71cb54f1d85286ebbd2 61 Gene3D G3DSA:4.10.830.10 4 61 8.3E-25 T 09-03-2017 L21SP3_RS06145 287adc0a3e59d71cb54f1d85286ebbd2 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 6.6E-23 T 09-03-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06145 287adc0a3e59d71cb54f1d85286ebbd2 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 09-03-2017 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06145 287adc0a3e59d71cb54f1d85286ebbd2 61 SUPERFAMILY SSF57716 8 61 1.43E-19 T 09-03-2017 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 Gene3D G3DSA:3.40.50.620 421 662 2.3E-127 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 Gene3D G3DSA:3.40.50.620 16 203 2.3E-127 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 586 595 2.0E-30 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 54 65 2.0E-30 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 416 431 2.0E-30 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 553 566 2.0E-30 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 242 265 2.0E-30 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 5 941 19.316 T 09-03-2017 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 SUPERFAMILY SSF47323 677 942 2.43E-64 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 SUPERFAMILY SSF50677 207 418 7.74E-46 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 18 865 2.2E-274 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 Gene3D G3DSA:1.10.730.10 667 850 1.5E-42 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 31 665 1.0E-186 T 09-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 61 72 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 Pfam PF06827 Zinc finger found in FPG and IleRS 912 937 8.4E-9 T 09-03-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 Gene3D G3DSA:3.90.740.10 209 404 3.6E-52 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 SUPERFAMILY SSF52374 7 205 2.22E-129 T 09-03-2017 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 SUPERFAMILY SSF52374 418 672 2.22E-129 T 09-03-2017 L21SP3_RS02995 a6a017bc1471fdf2e6291ef47fe6d0c4 946 Pfam PF08264 Anticodon-binding domain of tRNA 709 865 1.3E-29 T 09-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 L21SP3_RS06395 58f25b27ec3dc9a3e770985d1d9a5971 369 Pfam PF02674 Colicin V production protein 25 128 1.3E-11 T 09-03-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 L21SP3_RS04785 a681e2157897b1d113cc2c1b54e8b6ca 343 Gene3D G3DSA:3.90.25.10 180 252 1.4E-6 T 09-03-2017 L21SP3_RS04785 a681e2157897b1d113cc2c1b54e8b6ca 343 Pfam PF08485 Polysaccharide biosynthesis protein C-terminal 286 333 5.6E-19 T 09-03-2017 IPR013692 UDP-glucose 4-epimerase CapD, C-terminal domain GO:0003978|GO:0009103 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344 L21SP3_RS04785 a681e2157897b1d113cc2c1b54e8b6ca 343 SUPERFAMILY SSF51735 1 262 3.47E-55 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04785 a681e2157897b1d113cc2c1b54e8b6ca 343 Pfam PF02719 Polysaccharide biosynthesis protein 9 283 7.4E-100 T 09-03-2017 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain L21SP3_RS04785 a681e2157897b1d113cc2c1b54e8b6ca 343 Gene3D G3DSA:3.40.50.720 7 179 1.1E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 Pfam PF05524 PEP-utilising enzyme, N-terminal 195 316 2.7E-17 T 09-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 Pfam PF00391 PEP-utilising enzyme, mobile domain 344 414 8.6E-14 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 449 729 1.4E-96 T 09-03-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 SUPERFAMILY SSF47831 232 332 7.32E-21 T 09-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 688 700 9.5E-20 T 09-03-2017 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 635 650 9.5E-20 T 09-03-2017 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 652 667 9.5E-20 T 09-03-2017 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 481 500 9.5E-20 T 09-03-2017 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 SMART SM00065 22 169 1.5E-11 T 09-03-2017 IPR003018 GAF domain GO:0005515 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 SUPERFAMILY SSF55781 12 165 1.46E-27 T 09-03-2017 IPR029016 GAF domain-like L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 Pfam PF13185 GAF domain 22 160 4.7E-13 T 09-03-2017 IPR003018 GAF domain GO:0005515 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 Gene3D G3DSA:3.20.20.60 450 755 3.6E-99 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 Gene3D G3DSA:3.30.450.40 12 163 6.2E-34 T 09-03-2017 IPR029016 GAF domain-like L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 SUPERFAMILY SSF51621 450 730 4.19E-94 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 194 754 5.6E-142 T 09-03-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 Gene3D G3DSA:3.50.30.10 324 437 4.4E-25 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 SUPERFAMILY SSF52009 316 432 2.49E-22 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP3_RS04160 72c04980cf3cc1bf9108ecf1f789084c 757 Gene3D G3DSA:1.10.274.10 233 323 2.3E-22 T 09-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 L21SP3_RS08110 aa87a1b3216fd1cf67fc41312b5dcda9 483 ProSitePatterns PS00149 Sulfatases signature 2. 101 111 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS08110 aa87a1b3216fd1cf67fc41312b5dcda9 483 Gene3D G3DSA:3.40.720.10 2 374 1.8E-97 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08110 aa87a1b3216fd1cf67fc41312b5dcda9 483 Pfam PF00884 Sulfatase 4 353 2.9E-64 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS08110 aa87a1b3216fd1cf67fc41312b5dcda9 483 Gene3D G3DSA:3.30.1120.10 392 460 5.6E-18 T 09-03-2017 L21SP3_RS08110 aa87a1b3216fd1cf67fc41312b5dcda9 483 SUPERFAMILY SSF53649 2 456 8.9E-113 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS01835 b4fcdccc196115719fddcaf099e044b1 302 SUPERFAMILY SSF56042 148 283 5.08E-25 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain L21SP3_RS01835 b4fcdccc196115719fddcaf099e044b1 302 Gene3D G3DSA:3.30.1330.10 11 139 2.7E-27 T 09-03-2017 IPR016188 PurM-like, N-terminal domain L21SP3_RS01835 b4fcdccc196115719fddcaf099e044b1 302 Gene3D G3DSA:3.90.650.10 172 301 5.5E-28 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain L21SP3_RS01835 b4fcdccc196115719fddcaf099e044b1 302 Pfam PF02769 AIR synthase related protein, C-terminal domain 192 283 1.4E-5 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain L21SP3_RS01835 b4fcdccc196115719fddcaf099e044b1 302 Pfam PF00586 AIR synthase related protein, N-terminal domain 41 133 6.7E-15 T 09-03-2017 IPR016188 PurM-like, N-terminal domain L21SP3_RS01835 b4fcdccc196115719fddcaf099e044b1 302 PIRSF PIRSF005303 5 301 6.8E-70 T 09-03-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 L21SP3_RS01835 b4fcdccc196115719fddcaf099e044b1 302 SUPERFAMILY SSF55326 12 129 2.09E-23 T 09-03-2017 L21SP3_RS10215 d2279cba9de0fe7f78db5377c68506aa 453 Pfam PF05167 Uncharacterised ACR (DUF711) 14 417 1.0E-153 T 09-03-2017 IPR007841 Uncharacterised protein family UPF0210 L21SP3_RS10215 d2279cba9de0fe7f78db5377c68506aa 453 SUPERFAMILY SSF51998 4 448 8.79E-151 T 09-03-2017 L21SP3_RS10215 d2279cba9de0fe7f78db5377c68506aa 453 Gene3D G3DSA:3.20.70.20 3 453 6.1E-177 T 09-03-2017 L21SP3_RS10215 d2279cba9de0fe7f78db5377c68506aa 453 Hamap MF_01221 UPF0210 protein . 3 453 47.754 T 09-03-2017 IPR007841 Uncharacterised protein family UPF0210 L21SP3_RS00895 35e8d79ebcb21d096807ce9f0414feb4 237 SUPERFAMILY SSF53067 117 224 5.05E-12 T 09-03-2017 L21SP3_RS00895 35e8d79ebcb21d096807ce9f0414feb4 237 Gene3D G3DSA:3.30.420.40 129 191 3.0E-8 T 09-03-2017 L21SP3_RS00895 35e8d79ebcb21d096807ce9f0414feb4 237 SUPERFAMILY SSF53067 4 102 4.32E-19 T 09-03-2017 L21SP3_RS00895 35e8d79ebcb21d096807ce9f0414feb4 237 Gene3D G3DSA:3.30.420.40 4 128 2.6E-29 T 09-03-2017 L21SP3_RS00895 35e8d79ebcb21d096807ce9f0414feb4 237 Pfam PF00814 Glycoprotease family 35 166 7.0E-23 T 09-03-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP3_RS00895 35e8d79ebcb21d096807ce9f0414feb4 237 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 5 226 2.0E-45 T 09-03-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 L21SP3_RS00705 42cf5feaa9e99184dfdb509a763720f8 152 SMART SM00448 9 122 1.6E-36 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS00705 42cf5feaa9e99184dfdb509a763720f8 152 Pfam PF00072 Response regulator receiver domain 11 123 8.4E-29 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS00705 42cf5feaa9e99184dfdb509a763720f8 152 SUPERFAMILY SSF52172 7 141 6.55E-41 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS00705 42cf5feaa9e99184dfdb509a763720f8 152 Gene3D G3DSA:3.40.50.2300 4 136 3.8E-42 T 09-03-2017 L21SP3_RS00235 aea60bf2f7c79964fb204975f446657c 204 Pfam PF07589 PEP-CTERM motif 183 203 3.5E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS00235 aea60bf2f7c79964fb204975f446657c 204 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 183 203 2.9E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS03645 b1effe99845730a4804429658745002f 125 Gene3D G3DSA:1.20.1290.10 12 118 2.5E-29 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 L21SP3_RS03645 b1effe99845730a4804429658745002f 125 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 55 103 1.1E-19 T 09-03-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 L21SP3_RS03645 b1effe99845730a4804429658745002f 125 SUPERFAMILY SSF69118 9 121 8.51E-29 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 L21SP3_RS03645 b1effe99845730a4804429658745002f 125 Pfam PF02627 Carboxymuconolactone decarboxylase family 50 111 4.1E-20 T 09-03-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 L21SP3_RS04965 c8baa4f1bb93d317c40eb7d10f27706b 206 Gene3D G3DSA:2.60.120.200 8 155 3.8E-20 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04965 c8baa4f1bb93d317c40eb7d10f27706b 206 SUPERFAMILY SSF49899 8 156 8.98E-22 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04965 c8baa4f1bb93d317c40eb7d10f27706b 206 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 9 152 2.6E-17 T 09-03-2017 L21SP3_RS00875 1de0fdc3ff5cf1330885d9e89cc1bd9a 560 Gene3D G3DSA:3.30.1120.10 476 559 4.1E-26 T 09-03-2017 L21SP3_RS00875 1de0fdc3ff5cf1330885d9e89cc1bd9a 560 Gene3D G3DSA:3.40.720.10 38 473 1.7E-126 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS00875 1de0fdc3ff5cf1330885d9e89cc1bd9a 560 Pfam PF00884 Sulfatase 41 447 1.6E-75 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS00875 1de0fdc3ff5cf1330885d9e89cc1bd9a 560 SUPERFAMILY SSF53649 39 553 1.16E-147 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS06020 a2d766c564e91c7cc0a7d58958920b70 214 Gene3D G3DSA:3.40.50.1980 2 73 3.5E-11 T 09-03-2017 L21SP3_RS06020 a2d766c564e91c7cc0a7d58958920b70 214 Pfam PF01497 Periplasmic binding protein 1 181 2.3E-21 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 L21SP3_RS06020 a2d766c564e91c7cc0a7d58958920b70 214 SUPERFAMILY SSF53807 2 201 9.81E-35 T 09-03-2017 L21SP3_RS06020 a2d766c564e91c7cc0a7d58958920b70 214 Gene3D G3DSA:3.40.50.1980 77 202 6.9E-22 T 09-03-2017 L21SP3_RS02935 6d05f0dc14b6bff1528ad7cc400a9888 221 SUPERFAMILY SSF102114 22 112 1.57E-17 T 09-03-2017 L21SP3_RS02935 6d05f0dc14b6bff1528ad7cc400a9888 221 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 1 215 35.538 T 09-03-2017 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 L21SP3_RS02935 6d05f0dc14b6bff1528ad7cc400a9888 221 Pfam PF13394 4Fe-4S single cluster domain 22 104 3.0E-14 T 09-03-2017 L21SP3_RS02935 6d05f0dc14b6bff1528ad7cc400a9888 221 Pfam PF04055 Radical SAM superfamily 24 108 3.5E-14 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS02935 6d05f0dc14b6bff1528ad7cc400a9888 221 Gene3D G3DSA:3.20.20.70 26 111 7.3E-18 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS02935 6d05f0dc14b6bff1528ad7cc400a9888 221 PIRSF PIRSF000370 1 214 1.7E-43 T 09-03-2017 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 L21SP3_RS08225 d0619b186e5ef11155452d9b995e5402 394 SUPERFAMILY SSF48208 55 393 3.97E-51 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS08225 d0619b186e5ef11155452d9b995e5402 394 Pfam PF07470 Glycosyl Hydrolase Family 88 51 392 4.9E-82 T 09-03-2017 IPR010905 Glycosyl hydrolase, family 88 L21SP3_RS08225 d0619b186e5ef11155452d9b995e5402 394 Gene3D G3DSA:1.50.10.10 39 392 2.9E-89 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 Gene3D G3DSA:1.10.10.650 1 109 3.8E-42 T 09-03-2017 IPR023319 Tex-like protein, HTH domain L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 SUPERFAMILY SSF47781 548 619 4.45E-18 T 09-03-2017 IPR010994 RuvA domain 2-like L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 Gene3D G3DSA:1.10.3500.10 110 312 1.1E-93 T 09-03-2017 IPR023323 Tex-like domain L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 Gene3D G3DSA:1.10.3500.10 439 486 1.1E-93 T 09-03-2017 IPR023323 Tex-like domain L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 Pfam PF16921 Tex protein YqgF-like domain 316 438 5.0E-45 T 09-03-2017 IPR032639 Tex protein, YqgF-like domain L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 SMART SM00732 316 412 4.4E-26 T 09-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 SMART SM00316 637 708 1.7E-24 T 09-03-2017 IPR022967 RNA-binding domain, S1 L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 SUPERFAMILY SSF53098 314 457 6.83E-43 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 SUPERFAMILY SSF50249 626 717 3.06E-25 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 Gene3D G3DSA:3.30.420.140 316 438 6.0E-45 T 09-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 SUPERFAMILY SSF158832 2 311 1.83E-110 T 09-03-2017 L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 SUPERFAMILY SSF47781 458 546 5.67E-27 T 09-03-2017 IPR010994 RuvA domain 2-like L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 Pfam PF09371 Tex-like protein N-terminal domain 9 193 4.5E-70 T 09-03-2017 IPR018974 Tex-like protein, N-terminal L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 Gene3D G3DSA:2.40.50.140 632 709 3.0E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 Pfam PF12836 Helix-hairpin-helix motif 479 543 3.5E-25 T 09-03-2017 L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 Gene3D G3DSA:1.10.150.310 487 618 3.9E-45 T 09-03-2017 IPR023097 Tex RuvX-like domain L21SP3_RS08765 626c920d59bb2c60391c52c21ea1ee50 758 Pfam PF00575 S1 RNA binding domain 637 708 1.9E-18 T 09-03-2017 IPR003029 S1 domain GO:0003676 L21SP3_RS07515 aaad2dcad0440984119793300c87c75c 399 SUPERFAMILY SSF53822 48 281 1.31E-32 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS07515 aaad2dcad0440984119793300c87c75c 399 Gene3D G3DSA:3.40.50.2300 117 280 5.3E-28 T 09-03-2017 L21SP3_RS07515 aaad2dcad0440984119793300c87c75c 399 Gene3D G3DSA:3.40.50.2300 65 116 1.2E-4 T 09-03-2017 L21SP3_RS07515 aaad2dcad0440984119793300c87c75c 399 Pfam PF13377 Periplasmic binding protein-like domain 120 282 8.3E-32 T 09-03-2017 L21SP3_RS07515 aaad2dcad0440984119793300c87c75c 399 SMART SM00342 307 390 4.8E-20 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS07515 aaad2dcad0440984119793300c87c75c 399 Gene3D G3DSA:1.10.10.60 344 393 6.9E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS07515 aaad2dcad0440984119793300c87c75c 399 SUPERFAMILY SSF46689 343 394 4.93E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS07515 aaad2dcad0440984119793300c87c75c 399 Pfam PF12833 Helix-turn-helix domain 313 391 3.3E-17 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS07515 aaad2dcad0440984119793300c87c75c 399 Gene3D G3DSA:1.10.10.60 289 343 5.6E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS07515 aaad2dcad0440984119793300c87c75c 399 SUPERFAMILY SSF46689 290 338 4.67E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS08470 6f39ab8febc0ea2eee696a9188b0bcd3 501 SUPERFAMILY SSF52540 2 226 1.0E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08470 6f39ab8febc0ea2eee696a9188b0bcd3 501 SMART SM00382 287 465 1.1E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS08470 6f39ab8febc0ea2eee696a9188b0bcd3 501 SMART SM00382 28 218 3.8E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS08470 6f39ab8febc0ea2eee696a9188b0bcd3 501 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS08470 6f39ab8febc0ea2eee696a9188b0bcd3 501 SUPERFAMILY SSF52540 258 470 1.36E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08470 6f39ab8febc0ea2eee696a9188b0bcd3 501 ProSitePatterns PS00211 ABC transporters family signature. 389 403 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS08470 6f39ab8febc0ea2eee696a9188b0bcd3 501 Pfam PF00005 ABC transporter 19 170 1.8E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS08470 6f39ab8febc0ea2eee696a9188b0bcd3 501 Pfam PF00005 ABC transporter 278 417 2.7E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS08470 6f39ab8febc0ea2eee696a9188b0bcd3 501 Gene3D G3DSA:3.40.50.300 1 229 8.6E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08470 6f39ab8febc0ea2eee696a9188b0bcd3 501 Gene3D G3DSA:3.40.50.300 257 474 4.1E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03845 54d177073d3d8a4fcde205cd3b658ff4 246 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 113 207 5.6E-6 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP3_RS03845 54d177073d3d8a4fcde205cd3b658ff4 246 Pfam PF13419 Haloacid dehalogenase-like hydrolase 27 213 8.8E-24 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS03845 54d177073d3d8a4fcde205cd3b658ff4 246 SUPERFAMILY SSF56784 24 245 1.4E-34 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS03845 54d177073d3d8a4fcde205cd3b658ff4 246 Gene3D G3DSA:3.40.50.1000 23 241 1.4E-32 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS09410 d429a32073ffc1a2faf1dc4ec670ba75 444 Gene3D G3DSA:3.30.1120.10 378 441 2.7E-20 T 09-03-2017 L21SP3_RS09410 d429a32073ffc1a2faf1dc4ec670ba75 444 SUPERFAMILY SSF53649 11 432 2.74E-129 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09410 d429a32073ffc1a2faf1dc4ec670ba75 444 Gene3D G3DSA:3.40.720.10 10 377 4.4E-113 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS09410 d429a32073ffc1a2faf1dc4ec670ba75 444 Pfam PF00884 Sulfatase 11 343 4.3E-74 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS04080 0e345a2f7c19f3445672f28c05378a38 391 SUPERFAMILY SSF55298 286 382 1.03E-18 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like L21SP3_RS04080 0e345a2f7c19f3445672f28c05378a38 391 Gene3D G3DSA:3.30.1330.40 281 385 1.0E-18 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like L21SP3_RS04080 0e345a2f7c19f3445672f28c05378a38 391 Gene3D G3DSA:3.30.1330.40 157 237 3.6E-4 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like L21SP3_RS04080 0e345a2f7c19f3445672f28c05378a38 391 Pfam PF01042 Endoribonuclease L-PSP 286 380 1.5E-10 T 09-03-2017 IPR006175 YjgF/YER057c/UK114 family L21SP3_RS06350 868fcc92afc7b8f910ef432c9b752136 326 Gene3D G3DSA:3.90.25.10 175 300 5.2E-34 T 09-03-2017 L21SP3_RS06350 868fcc92afc7b8f910ef432c9b752136 326 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 319 3.0E-119 T 09-03-2017 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 L21SP3_RS06350 868fcc92afc7b8f910ef432c9b752136 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 246 2.8E-39 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 L21SP3_RS06350 868fcc92afc7b8f910ef432c9b752136 326 SUPERFAMILY SSF51735 2 324 1.06E-55 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS06350 868fcc92afc7b8f910ef432c9b752136 326 Gene3D G3DSA:3.40.50.720 2 174 1.9E-18 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS10670 15993dc4af9c0d4d3b9adc0156904a0c 762 SUPERFAMILY SSF51126 42 112 1.06E-39 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS10670 15993dc4af9c0d4d3b9adc0156904a0c 762 SUPERFAMILY SSF51126 372 639 1.06E-39 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS10670 15993dc4af9c0d4d3b9adc0156904a0c 762 Gene3D G3DSA:2.60.120.260 196 305 8.1E-33 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10670 15993dc4af9c0d4d3b9adc0156904a0c 762 Pfam PF07602 Protein of unknown function (DUF1565) 33 71 1.6E-4 T 09-03-2017 IPR011459 Domain of unknown function DUF1565 L21SP3_RS10670 15993dc4af9c0d4d3b9adc0156904a0c 762 SMART SM00606 192 323 5.0E-25 T 09-03-2017 IPR006584 Cellulose binding, type IV GO:0030246 L21SP3_RS10670 15993dc4af9c0d4d3b9adc0156904a0c 762 Pfam PF13229 Right handed beta helix region 406 590 6.4E-7 T 09-03-2017 L21SP3_RS10670 15993dc4af9c0d4d3b9adc0156904a0c 762 Gene3D G3DSA:2.160.20.10 15 115 9.4E-18 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS10670 15993dc4af9c0d4d3b9adc0156904a0c 762 Gene3D G3DSA:2.160.20.10 322 382 5.0E-11 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS10670 15993dc4af9c0d4d3b9adc0156904a0c 762 Gene3D G3DSA:2.160.20.10 449 660 5.0E-11 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS10670 15993dc4af9c0d4d3b9adc0156904a0c 762 SUPERFAMILY SSF49785 194 308 1.22E-24 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10670 15993dc4af9c0d4d3b9adc0156904a0c 762 Pfam PF03422 Carbohydrate binding module (family 6) 201 309 1.8E-27 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 L21SP3_RS09910 40bbc007bbf5c5f1caa2713b707d0729 515 Gene3D G3DSA:3.40.720.10 19 366 8.6E-114 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS09910 40bbc007bbf5c5f1caa2713b707d0729 515 Gene3D G3DSA:3.40.720.10 404 405 8.6E-114 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS09910 40bbc007bbf5c5f1caa2713b707d0729 515 Gene3D G3DSA:3.40.720.10 442 505 8.6E-114 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS09910 40bbc007bbf5c5f1caa2713b707d0729 515 Pfam PF00245 Alkaline phosphatase 31 499 6.4E-66 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS09910 40bbc007bbf5c5f1caa2713b707d0729 515 PRINTS PR00113 Alkaline phosphatase signature 258 287 4.2E-25 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS09910 40bbc007bbf5c5f1caa2713b707d0729 515 PRINTS PR00113 Alkaline phosphatase signature 172 182 4.2E-25 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS09910 40bbc007bbf5c5f1caa2713b707d0729 515 PRINTS PR00113 Alkaline phosphatase signature 31 51 4.2E-25 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS09910 40bbc007bbf5c5f1caa2713b707d0729 515 PRINTS PR00113 Alkaline phosphatase signature 90 105 4.2E-25 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS09910 40bbc007bbf5c5f1caa2713b707d0729 515 PRINTS PR00113 Alkaline phosphatase signature 128 148 4.2E-25 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS09910 40bbc007bbf5c5f1caa2713b707d0729 515 SUPERFAMILY SSF53649 22 375 1.7E-97 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09910 40bbc007bbf5c5f1caa2713b707d0729 515 SUPERFAMILY SSF53649 442 501 1.7E-97 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09910 40bbc007bbf5c5f1caa2713b707d0729 515 SMART SM00098 32 501 3.3E-27 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS09910 40bbc007bbf5c5f1caa2713b707d0729 515 ProSitePatterns PS00123 Alkaline phosphatase active site. 90 98 - T 09-03-2017 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 L21SP3_RS02920 72fdf0e2987ad4ee34b5da174ea4a289 210 Gene3D G3DSA:3.10.290.10 102 196 3.1E-25 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS02920 72fdf0e2987ad4ee34b5da174ea4a289 210 SMART SM01390 9 97 1.0E-20 T 09-03-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 L21SP3_RS02920 72fdf0e2987ad4ee34b5da174ea4a289 210 Pfam PF01479 S4 domain 99 145 1.4E-14 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS02920 72fdf0e2987ad4ee34b5da174ea4a289 210 SMART SM00363 98 160 9.0E-13 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS02920 72fdf0e2987ad4ee34b5da174ea4a289 210 SUPERFAMILY SSF55174 9 208 2.88E-49 T 09-03-2017 L21SP3_RS02920 72fdf0e2987ad4ee34b5da174ea4a289 210 Gene3D G3DSA:1.10.1050.10 7 101 9.5E-24 T 09-03-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 L21SP3_RS02920 72fdf0e2987ad4ee34b5da174ea4a289 210 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 10 97 2.8E-16 T 09-03-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 L21SP3_RS02920 72fdf0e2987ad4ee34b5da174ea4a289 210 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 10 209 4.4E-57 T 09-03-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 L21SP3_RS02920 72fdf0e2987ad4ee34b5da174ea4a289 210 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 7 210 26.891 T 09-03-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 L21SP3_RS09455 693162cb720cf6c4b05c0b02a013a9a3 324 Pfam PF06258 Mitochondrial fission ELM1 16 305 9.9E-34 T 09-03-2017 IPR009367 Mitochondrial fission protein ELM1-like L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 PIRSF PIRSF002401 1 335 4.1E-136 T 09-03-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 Hamap MF_01454 GTPase Obg [obg]. 1 328 47.069 T 09-03-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 319 8.2E-13 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 Pfam PF01018 GTP1/OBG 2 157 1.4E-60 T 09-03-2017 IPR006169 GTP1/OBG domain GO:0005525 L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 SUPERFAMILY SSF82051 2 157 1.57E-53 T 09-03-2017 IPR006169 GTP1/OBG domain GO:0005525 L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 SUPERFAMILY SSF52540 150 329 5.22E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 6.1E-33 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 6.1E-33 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 6.1E-33 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 6.1E-33 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 Pfam PF01926 50S ribosome-binding GTPase 160 283 2.6E-23 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 327 6.2E-138 T 09-03-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 Gene3D G3DSA:3.40.50.300 159 333 4.8E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03235 e20ba5791d8e951552cc4a264683328d 335 Gene3D G3DSA:2.70.210.12 2 155 1.8E-57 T 09-03-2017 IPR006169 GTP1/OBG domain GO:0005525 L21SP3_RS05315 555b4eb06574607491352911de05ec18 223 Pfam PF11907 Domain of unknown function (DUF3427) 21 216 2.2E-34 T 09-03-2017 IPR021835 Protein of unknown function DUF3427 L21SP3_RS02580 e6442e1195f7e9a9a651b508e3f13ec6 298 SUPERFAMILY SSF82689 171 268 6.15E-35 T 09-03-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 L21SP3_RS02580 e6442e1195f7e9a9a651b508e3f13ec6 298 Gene3D G3DSA:3.30.70.100 171 255 1.3E-32 T 09-03-2017 L21SP3_RS02580 e6442e1195f7e9a9a651b508e3f13ec6 298 Pfam PF00924 Mechanosensitive ion channel 60 257 3.0E-56 T 09-03-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 L21SP3_RS02580 e6442e1195f7e9a9a651b508e3f13ec6 298 SUPERFAMILY SSF82861 17 101 4.32E-12 T 09-03-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 L21SP3_RS02580 e6442e1195f7e9a9a651b508e3f13ec6 298 SUPERFAMILY SSF50182 103 168 1.44E-17 T 09-03-2017 IPR010920 LSM domain L21SP3_RS02580 e6442e1195f7e9a9a651b508e3f13ec6 298 Gene3D G3DSA:2.30.30.60 118 167 7.7E-16 T 09-03-2017 L21SP3_RS05140 d611d74e1cdabd1bf8fd4a6dc4897770 337 Gene3D G3DSA:3.40.50.10490 32 164 3.6E-11 T 09-03-2017 L21SP3_RS05140 d611d74e1cdabd1bf8fd4a6dc4897770 337 Gene3D G3DSA:3.40.50.10490 176 269 5.2E-6 T 09-03-2017 L21SP3_RS05140 d611d74e1cdabd1bf8fd4a6dc4897770 337 SUPERFAMILY SSF53697 15 285 1.02E-21 T 09-03-2017 L21SP3_RS01635 ef58f791b859c29df499e760d368c800 214 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 39 48 - T 09-03-2017 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 L21SP3_RS01635 ef58f791b859c29df499e760d368c800 214 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 9 209 2.3E-69 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 L21SP3_RS01635 ef58f791b859c29df499e760d368c800 214 Pfam PF01081 KDPG and KHG aldolase 10 202 5.4E-61 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 L21SP3_RS01635 ef58f791b859c29df499e760d368c800 214 Gene3D G3DSA:3.20.20.70 4 210 4.0E-71 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS01635 ef58f791b859c29df499e760d368c800 214 SUPERFAMILY SSF51569 5 211 1.06E-62 T 09-03-2017 L21SP3_RS09310 741c106b9b6eb6d71599321ad47e79ca 759 Gene3D G3DSA:2.60.120.200 490 704 5.8E-22 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS09310 741c106b9b6eb6d71599321ad47e79ca 759 SUPERFAMILY SSF48726 397 488 2.71E-13 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS09310 741c106b9b6eb6d71599321ad47e79ca 759 Pfam PF07679 Immunoglobulin I-set domain 397 487 1.1E-9 T 09-03-2017 IPR013098 Immunoglobulin I-set L21SP3_RS09310 741c106b9b6eb6d71599321ad47e79ca 759 SMART SM00408 409 477 4.8E-5 T 09-03-2017 IPR003598 Immunoglobulin subtype 2 L21SP3_RS09310 741c106b9b6eb6d71599321ad47e79ca 759 SUPERFAMILY SSF49899 489 705 2.96E-23 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS09310 741c106b9b6eb6d71599321ad47e79ca 759 Gene3D G3DSA:2.60.40.10 397 489 2.8E-13 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS09310 741c106b9b6eb6d71599321ad47e79ca 759 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 559 701 1.2E-19 T 09-03-2017 L21SP3_RS09310 741c106b9b6eb6d71599321ad47e79ca 759 SMART SM00409 403 489 2.2E-8 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS03855 bc675ed1c3096edebf7d8efa1596fe11 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 163 1.8E-18 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03855 bc675ed1c3096edebf7d8efa1596fe11 174 SUPERFAMILY SSF88946 4 87 1.6E-14 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03855 bc675ed1c3096edebf7d8efa1596fe11 174 SUPERFAMILY SSF88659 101 164 2.24E-8 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03855 bc675ed1c3096edebf7d8efa1596fe11 174 Gene3D G3DSA:1.10.1740.10 3 85 2.0E-15 T 09-03-2017 L21SP3_RS03855 bc675ed1c3096edebf7d8efa1596fe11 174 Pfam PF04542 Sigma-70 region 2 16 75 1.9E-10 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03410 98222a1ec1fb5d56b7567bb0d69e2f3f 333 Pfam PF01515 Phosphate acetyl/butaryl transferase 7 328 7.6E-122 T 09-03-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 L21SP3_RS03410 98222a1ec1fb5d56b7567bb0d69e2f3f 333 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 22 328 3.0E-113 T 09-03-2017 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 L21SP3_RS03410 98222a1ec1fb5d56b7567bb0d69e2f3f 333 SUPERFAMILY SSF53659 7 330 2.1E-87 T 09-03-2017 L21SP3_RS03410 98222a1ec1fb5d56b7567bb0d69e2f3f 333 Gene3D G3DSA:3.40.50.10750 140 304 3.4E-62 T 09-03-2017 L21SP3_RS03410 98222a1ec1fb5d56b7567bb0d69e2f3f 333 PIRSF PIRSF000428 3 333 1.6E-104 T 09-03-2017 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 L21SP3_RS05285 56691e9ed529934a95b836493a8eb9f0 313 Pfam PF13091 PLD-like domain 138 268 2.4E-11 T 09-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 L21SP3_RS05285 56691e9ed529934a95b836493a8eb9f0 313 SUPERFAMILY SSF56024 127 270 1.92E-9 T 09-03-2017 L21SP3_RS05285 56691e9ed529934a95b836493a8eb9f0 313 Gene3D G3DSA:3.30.870.10 127 272 3.6E-8 T 09-03-2017 L21SP3_RS11125 79405e0fb9c7bb9ebf11dec823ae94ff 85 Gene3D G3DSA:3.30.70.1150 2 83 3.9E-14 T 09-03-2017 L21SP3_RS11125 79405e0fb9c7bb9ebf11dec823ae94ff 85 SUPERFAMILY SSF55021 1 82 8.7E-14 T 09-03-2017 L21SP3_RS08345 4a778152a84bd1d53585960a1ad136ae 277 Pfam PF07589 PEP-CTERM motif 250 265 1.3E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS08345 4a778152a84bd1d53585960a1ad136ae 277 Gene3D G3DSA:3.10.20.10 156 189 0.001 T 09-03-2017 L21SP3_RS08345 4a778152a84bd1d53585960a1ad136ae 277 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 251 271 0.0035 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS02260 5bf1cd69b11809cdc1d7d3b357453f25 270 Gene3D G3DSA:3.30.700.10 8 63 3.0E-6 T 09-03-2017 L21SP3_RS02260 5bf1cd69b11809cdc1d7d3b357453f25 270 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 227 239 4.0E-4 T 09-03-2017 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP3_RS02260 5bf1cd69b11809cdc1d7d3b357453f25 270 Pfam PF13633 Prokaryotic N-terminal methylation site 6 31 4.4E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS02260 5bf1cd69b11809cdc1d7d3b357453f25 270 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 27 6.5E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS02260 5bf1cd69b11809cdc1d7d3b357453f25 270 SUPERFAMILY SSF54523 8 97 1.65E-17 T 09-03-2017 L21SP3_RS02260 5bf1cd69b11809cdc1d7d3b357453f25 270 Pfam PF07596 Protein of unknown function (DUF1559) 33 78 1.1E-4 T 09-03-2017 IPR011453 Protein of unknown function DUF1559 L21SP3_RS08200 7de28e319e946dba77f40e646efd001b 695 Pfam PF11175 Protein of unknown function (DUF2961) 119 209 8.4E-6 T 09-03-2017 IPR021345 Protein of unknown function DUF2961 L21SP3_RS08200 7de28e319e946dba77f40e646efd001b 695 Pfam PF11175 Protein of unknown function (DUF2961) 285 522 8.4E-59 T 09-03-2017 IPR021345 Protein of unknown function DUF2961 L21SP3_RS00345 c23505054c334d0e02b3813cc17e9f98 403 Pfam PF00365 Phosphofructokinase 11 325 9.4E-45 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS00345 c23505054c334d0e02b3813cc17e9f98 403 PIRSF PIRSF036483 5 399 1.1E-119 T 09-03-2017 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 L21SP3_RS00345 c23505054c334d0e02b3813cc17e9f98 403 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 6 401 37.46 T 09-03-2017 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 L21SP3_RS00345 c23505054c334d0e02b3813cc17e9f98 403 Gene3D G3DSA:3.40.50.450 4 230 2.9E-48 T 09-03-2017 L21SP3_RS00345 c23505054c334d0e02b3813cc17e9f98 403 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 255 277 1.4E-5 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS00345 c23505054c334d0e02b3813cc17e9f98 403 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 134 151 1.4E-5 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS00345 c23505054c334d0e02b3813cc17e9f98 403 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 11 30 1.4E-5 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS00345 c23505054c334d0e02b3813cc17e9f98 403 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 172 188 1.4E-5 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS00345 c23505054c334d0e02b3813cc17e9f98 403 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 230 242 1.4E-5 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS00345 c23505054c334d0e02b3813cc17e9f98 403 SUPERFAMILY SSF53784 6 390 9.68E-81 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS07070 b526efa181f5be69b0c48bf3384eb9b7 185 SUPERFAMILY SSF55469 6 182 9.68E-48 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 L21SP3_RS07070 b526efa181f5be69b0c48bf3384eb9b7 185 Pfam PF00881 Nitroreductase family 69 154 1.6E-9 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 L21SP3_RS07070 b526efa181f5be69b0c48bf3384eb9b7 185 Pfam PF00881 Nitroreductase family 15 65 1.4E-14 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 L21SP3_RS07070 b526efa181f5be69b0c48bf3384eb9b7 185 Gene3D G3DSA:3.40.109.10 3 182 1.1E-49 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 L21SP3_RS11780 5e3c193d0a67ac315662c020da36d9b2 556 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 461 553 3.8E-23 T 09-03-2017 IPR007859 ETF-QO/FixX GO:0051536|GO:0055114 Reactome: R-HSA-611105 L21SP3_RS11780 5e3c193d0a67ac315662c020da36d9b2 556 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 526 537 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS11780 5e3c193d0a67ac315662c020da36d9b2 556 Gene3D G3DSA:3.30.9.10 273 387 2.3E-5 T 09-03-2017 L21SP3_RS11780 5e3c193d0a67ac315662c020da36d9b2 556 SUPERFAMILY SSF54862 471 550 8.27E-15 T 09-03-2017 L21SP3_RS11780 5e3c193d0a67ac315662c020da36d9b2 556 SUPERFAMILY SSF51905 335 403 3.12E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS11780 5e3c193d0a67ac315662c020da36d9b2 556 SUPERFAMILY SSF51905 8 61 3.12E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS11780 5e3c193d0a67ac315662c020da36d9b2 556 SUPERFAMILY SSF51905 122 224 3.12E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS11780 5e3c193d0a67ac315662c020da36d9b2 556 Pfam PF00890 FAD binding domain 11 55 5.8E-6 T 09-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 L21SP3_RS11780 5e3c193d0a67ac315662c020da36d9b2 556 Gene3D G3DSA:3.50.50.60 9 241 5.0E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS11780 5e3c193d0a67ac315662c020da36d9b2 556 SUPERFAMILY SSF54373 225 328 1.33E-14 T 09-03-2017 L21SP3_RS11780 5e3c193d0a67ac315662c020da36d9b2 556 Gene3D G3DSA:3.30.70.20 489 543 1.2E-6 T 09-03-2017 L21SP3_RS03925 ce2afe8a5453d9b56ec36044e581b6bf 380 SMART SM00342 294 377 1.1E-17 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS03925 ce2afe8a5453d9b56ec36044e581b6bf 380 SUPERFAMILY SSF46689 330 377 7.62E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS03925 ce2afe8a5453d9b56ec36044e581b6bf 380 Gene3D G3DSA:3.40.50.2300 93 270 2.2E-28 T 09-03-2017 L21SP3_RS03925 ce2afe8a5453d9b56ec36044e581b6bf 380 Gene3D G3DSA:1.10.10.60 277 330 1.6E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS03925 ce2afe8a5453d9b56ec36044e581b6bf 380 Pfam PF13377 Periplasmic binding protein-like domain 108 270 3.9E-29 T 09-03-2017 L21SP3_RS03925 ce2afe8a5453d9b56ec36044e581b6bf 380 SUPERFAMILY SSF53822 5 270 1.51E-31 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS03925 ce2afe8a5453d9b56ec36044e581b6bf 380 Pfam PF12833 Helix-turn-helix domain 301 377 6.6E-19 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS03925 ce2afe8a5453d9b56ec36044e581b6bf 380 Gene3D G3DSA:1.10.10.60 331 378 1.4E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS11755 ecba40f187fab6859cef05c0698fdbdf 375 Pfam PF13784 Fic/DOC family N-terminal 39 118 3.0E-23 T 09-03-2017 IPR025758 Fic/DOC N-terminal L21SP3_RS11755 ecba40f187fab6859cef05c0698fdbdf 375 Gene3D G3DSA:1.10.3290.10 39 300 5.9E-66 T 09-03-2017 IPR003812 Fido domain L21SP3_RS11755 ecba40f187fab6859cef05c0698fdbdf 375 Pfam PF02661 Fic/DOC family 124 229 2.3E-21 T 09-03-2017 IPR003812 Fido domain L21SP3_RS11755 ecba40f187fab6859cef05c0698fdbdf 375 PIRSF PIRSF038925 14 375 3.3E-110 T 09-03-2017 IPR026287 Adenosine monophosphate-protein transferase L21SP3_RS11755 ecba40f187fab6859cef05c0698fdbdf 375 SUPERFAMILY SSF140931 102 296 5.1E-47 T 09-03-2017 IPR003812 Fido domain L21SP3_RS03525 3a74164eda6a46d27b6e87147a4f3ef6 237 Gene3D G3DSA:3.40.1280.10 3 231 1.8E-56 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal L21SP3_RS03525 3a74164eda6a46d27b6e87147a4f3ef6 237 SUPERFAMILY SSF75217 72 232 3.61E-37 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases L21SP3_RS03525 3a74164eda6a46d27b6e87147a4f3ef6 237 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 3 230 6.1E-46 T 09-03-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS03525 3a74164eda6a46d27b6e87147a4f3ef6 237 PIRSF PIRSF015601 1 235 3.9E-55 T 09-03-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS03525 3a74164eda6a46d27b6e87147a4f3ef6 237 Pfam PF04452 RNA methyltransferase 15 228 1.2E-53 T 09-03-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 L21SP3_RS03525 3a74164eda6a46d27b6e87147a4f3ef6 237 SUPERFAMILY SSF88697 3 62 5.47E-8 T 09-03-2017 IPR015947 PUA-like domain L21SP3_RS04285 f0c57e943782c92ad8e6bfe45176b500 287 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 11 284 4.2E-88 T 09-03-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 L21SP3_RS04285 f0c57e943782c92ad8e6bfe45176b500 287 Pfam PF05681 Fumarate hydratase (Fumerase) 11 285 2.0E-107 T 09-03-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 L21SP3_RS04510 58b3cace9c264912a4758e29a9e6337c 387 Pfam PF07593 ASPIC and UnbV 272 339 1.6E-6 T 09-03-2017 IPR011519 ASPIC/UnbV L21SP3_RS04510 58b3cace9c264912a4758e29a9e6337c 387 Gene3D G3DSA:2.130.10.130 47 111 1.4E-10 T 09-03-2017 L21SP3_RS04510 58b3cace9c264912a4758e29a9e6337c 387 Gene3D G3DSA:2.130.10.130 148 272 1.4E-10 T 09-03-2017 L21SP3_RS04510 58b3cace9c264912a4758e29a9e6337c 387 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 156 223 2.2E-9 T 09-03-2017 L21SP3_RS04510 58b3cace9c264912a4758e29a9e6337c 387 SUPERFAMILY SSF69318 46 253 8.24E-17 T 09-03-2017 L21SP3_RS07680 417be9bababcda8965fc643f5562c0a7 126 Gene3D G3DSA:2.60.40.730 3 125 1.2E-46 T 09-03-2017 L21SP3_RS07680 417be9bababcda8965fc643f5562c0a7 126 SUPERFAMILY SSF49367 40 125 8.37E-33 T 09-03-2017 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 L21SP3_RS07680 417be9bababcda8965fc643f5562c0a7 126 SUPERFAMILY SSF57802 3 37 3.85E-9 T 09-03-2017 L21SP3_RS07680 417be9bababcda8965fc643f5562c0a7 126 Pfam PF01880 Desulfoferrodoxin 42 124 3.3E-21 T 09-03-2017 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 L21SP3_RS07680 417be9bababcda8965fc643f5562c0a7 126 TIGRFAM TIGR00320 dfx_rbo: desulfoferrodoxin 1 125 3.5E-55 T 09-03-2017 IPR004793 Desulfoferrodoxin GO:0005506|GO:0019430 L21SP3_RS07680 417be9bababcda8965fc643f5562c0a7 126 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 41 125 4.1E-25 T 09-03-2017 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 L21SP3_RS07680 417be9bababcda8965fc643f5562c0a7 126 Pfam PF06397 Desulfoferrodoxin, N-terminal domain 3 37 1.7E-9 T 09-03-2017 IPR004462 Desulfoferrodoxin Dfx GO:0005506 L21SP3_RS06490 934d9d7110fe130563d5cf5a064e3ac4 374 PIRSF PIRSF001092 21 372 3.7E-86 T 09-03-2017 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 L21SP3_RS06490 934d9d7110fe130563d5cf5a064e3ac4 374 Pfam PF01120 Alpha-L-fucosidase 48 371 1.1E-69 T 09-03-2017 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51 L21SP3_RS06490 934d9d7110fe130563d5cf5a064e3ac4 374 Gene3D G3DSA:3.20.20.80 43 371 1.1E-82 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS06490 934d9d7110fe130563d5cf5a064e3ac4 374 SUPERFAMILY SSF51445 48 371 2.02E-77 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS06490 934d9d7110fe130563d5cf5a064e3ac4 374 SMART SM00812 43 372 7.2E-55 T 09-03-2017 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51 L21SP3_RS10505 a9d2409d63275539ddaae0c4d2642d14 386 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 139 208 4.5E-5 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 L21SP3_RS10505 a9d2409d63275539ddaae0c4d2642d14 386 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 127 1.8E-25 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP3_RS10505 a9d2409d63275539ddaae0c4d2642d14 386 SUPERFAMILY SSF55347 132 307 3.92E-25 T 09-03-2017 L21SP3_RS10505 a9d2409d63275539ddaae0c4d2642d14 386 Gene3D G3DSA:3.40.50.720 2 144 1.4E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS10505 a9d2409d63275539ddaae0c4d2642d14 386 Gene3D G3DSA:3.30.360.10 145 367 4.9E-30 T 09-03-2017 L21SP3_RS10505 a9d2409d63275539ddaae0c4d2642d14 386 SUPERFAMILY SSF51735 3 155 3.38E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS01345 a1e133cffd9066e040da2a14de627648 504 SUPERFAMILY SSF56037 411 495 4.45E-8 T 09-03-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 L21SP3_RS01345 a1e133cffd9066e040da2a14de627648 504 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 55 244 7.3E-52 T 09-03-2017 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 L21SP3_RS01345 a1e133cffd9066e040da2a14de627648 504 SUPERFAMILY SSF52402 45 262 9.18E-50 T 09-03-2017 L21SP3_RS01345 a1e133cffd9066e040da2a14de627648 504 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 36 353 22.053 T 09-03-2017 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 L21SP3_RS01345 a1e133cffd9066e040da2a14de627648 504 SMART SM00977 422 495 3.1E-7 T 09-03-2017 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 L21SP3_RS01345 a1e133cffd9066e040da2a14de627648 504 Pfam PF01171 PP-loop family 55 240 1.2E-50 T 09-03-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 L21SP3_RS01345 a1e133cffd9066e040da2a14de627648 504 Gene3D G3DSA:3.40.50.620 35 223 8.5E-20 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS05960 7e623cfcb1db446791f1b2ed11749a64 144 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 8 139 4.7E-39 T 09-03-2017 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 L21SP3_RS05960 7e623cfcb1db446791f1b2ed11749a64 144 Gene3D G3DSA:3.30.700.10 10 76 2.1E-6 T 09-03-2017 L21SP3_RS05960 7e623cfcb1db446791f1b2ed11749a64 144 Pfam PF08334 Type II secretion system (T2SS), protein G 33 139 4.5E-32 T 09-03-2017 IPR013545 Type II secretion system protein G L21SP3_RS05960 7e623cfcb1db446791f1b2ed11749a64 144 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS05960 7e623cfcb1db446791f1b2ed11749a64 144 PRINTS PR00813 Bacterial general secretion pathway protein G signature 9 34 2.4E-11 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS05960 7e623cfcb1db446791f1b2ed11749a64 144 PRINTS PR00813 Bacterial general secretion pathway protein G signature 45 63 2.4E-11 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS05960 7e623cfcb1db446791f1b2ed11749a64 144 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 5 29 9.9E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS05960 7e623cfcb1db446791f1b2ed11749a64 144 SUPERFAMILY SSF54523 36 140 3.66E-26 T 09-03-2017 L21SP3_RS05960 7e623cfcb1db446791f1b2ed11749a64 144 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 3.4E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS09245 442ad029666022a4887c815548753e69 186 ProSitePatterns PS01275 Elongation factor P signature. 149 168 - T 09-03-2017 IPR013852 Translation elongation factor P/YeiP, conserved site L21SP3_RS09245 442ad029666022a4887c815548753e69 186 SUPERFAMILY SSF50249 64 128 1.63E-15 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS09245 442ad029666022a4887c815548753e69 186 SUPERFAMILY SSF50249 127 184 4.28E-18 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS09245 442ad029666022a4887c815548753e69 186 Hamap MF_00141 Elongation factor P [efp]. 1 184 41.998 T 09-03-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 L21SP3_RS09245 442ad029666022a4887c815548753e69 186 SMART SM01185 66 120 8.0E-19 T 09-03-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 L21SP3_RS09245 442ad029666022a4887c815548753e69 186 PIRSF PIRSF005901 1 185 1.3E-65 T 09-03-2017 IPR020599 Translation elongation factor P/YeiP L21SP3_RS09245 442ad029666022a4887c815548753e69 186 Gene3D G3DSA:2.40.50.140 127 184 3.4E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS09245 442ad029666022a4887c815548753e69 186 TIGRFAM TIGR00038 efp: translation elongation factor P 2 184 1.4E-70 T 09-03-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 L21SP3_RS09245 442ad029666022a4887c815548753e69 186 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 2 58 8.2E-21 T 09-03-2017 IPR013185 Translation elongation factor, KOW-like L21SP3_RS09245 442ad029666022a4887c815548753e69 186 SUPERFAMILY SSF50104 2 62 1.87E-17 T 09-03-2017 IPR008991 Translation protein SH3-like domain L21SP3_RS09245 442ad029666022a4887c815548753e69 186 Pfam PF01132 Elongation factor P (EF-P) OB domain 67 120 1.4E-18 T 09-03-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 L21SP3_RS09245 442ad029666022a4887c815548753e69 186 Gene3D G3DSA:2.30.30.30 2 62 4.9E-22 T 09-03-2017 IPR014722 Ribosomal protein L2 domain 2 L21SP3_RS09245 442ad029666022a4887c815548753e69 186 Gene3D G3DSA:2.40.50.140 64 126 5.6E-22 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS09245 442ad029666022a4887c815548753e69 186 Pfam PF09285 Elongation factor P, C-terminal 128 183 1.9E-25 T 09-03-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 L21SP3_RS09245 442ad029666022a4887c815548753e69 186 SMART SM00841 128 183 1.8E-31 T 09-03-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 L21SP3_RS01935 e4d07c5c5151f4b49471a40d0feaa668 600 SUPERFAMILY SSF49899 20 221 1.9E-30 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS01935 e4d07c5c5151f4b49471a40d0feaa668 600 SUPERFAMILY SSF49899 344 521 8.02E-17 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS01935 e4d07c5c5151f4b49471a40d0feaa668 600 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 383 520 7.4E-11 T 09-03-2017 L21SP3_RS01935 e4d07c5c5151f4b49471a40d0feaa668 600 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 83 215 1.5E-20 T 09-03-2017 L21SP3_RS01935 e4d07c5c5151f4b49471a40d0feaa668 600 Gene3D G3DSA:2.60.120.200 343 521 4.2E-21 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS01935 e4d07c5c5151f4b49471a40d0feaa668 600 Gene3D G3DSA:2.60.120.200 20 221 1.8E-28 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05560 2431fe081e77449be6fa5407c2bd9dee 422 Pfam PF01609 Transposase DDE domain 275 412 1.5E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS05560 2431fe081e77449be6fa5407c2bd9dee 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.7E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS05500 2431fe081e77449be6fa5407c2bd9dee 422 Pfam PF01609 Transposase DDE domain 275 412 1.5E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS05500 2431fe081e77449be6fa5407c2bd9dee 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.7E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS03900 2431fe081e77449be6fa5407c2bd9dee 422 Pfam PF01609 Transposase DDE domain 275 412 1.5E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS03900 2431fe081e77449be6fa5407c2bd9dee 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.7E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS07530 41b3fe6d3f1e4e5312556b6cdaa236ce 270 SUPERFAMILY SSF54523 6 74 1.8E-13 T 09-03-2017 L21SP3_RS07530 41b3fe6d3f1e4e5312556b6cdaa236ce 270 Gene3D G3DSA:3.30.700.10 6 57 6.8E-6 T 09-03-2017 L21SP3_RS07530 41b3fe6d3f1e4e5312556b6cdaa236ce 270 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 25 1.4E-6 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS07530 41b3fe6d3f1e4e5312556b6cdaa236ce 270 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 213 228 6.1E-6 T 09-03-2017 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP3_RS07530 41b3fe6d3f1e4e5312556b6cdaa236ce 270 Pfam PF13633 Prokaryotic N-terminal methylation site 4 29 1.5E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS02670 7d097213173154c24b64db7edd3671bf 527 Gene3D G3DSA:3.40.50.720 1 106 1.8E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS02670 7d097213173154c24b64db7edd3671bf 527 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 09-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 L21SP3_RS02670 7d097213173154c24b64db7edd3671bf 527 SUPERFAMILY SSF55021 455 522 8.74E-11 T 09-03-2017 L21SP3_RS02670 7d097213173154c24b64db7edd3671bf 527 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 282 9.0E-58 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 L21SP3_RS02670 7d097213173154c24b64db7edd3671bf 527 Gene3D G3DSA:3.30.1330.90 321 447 1.1E-36 T 09-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 L21SP3_RS02670 7d097213173154c24b64db7edd3671bf 527 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 523 3.4E-180 T 09-03-2017 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 L21SP3_RS02670 7d097213173154c24b64db7edd3671bf 527 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 314 4.0E-33 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 L21SP3_RS02670 7d097213173154c24b64db7edd3671bf 527 SUPERFAMILY SSF51735 101 283 1.9E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS02670 7d097213173154c24b64db7edd3671bf 527 SUPERFAMILY SSF52283 1 135 5.29E-34 T 09-03-2017 L21SP3_RS02670 7d097213173154c24b64db7edd3671bf 527 Gene3D G3DSA:3.40.50.720 107 284 1.7E-62 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS02670 7d097213173154c24b64db7edd3671bf 527 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site L21SP3_RS02670 7d097213173154c24b64db7edd3671bf 527 Gene3D G3DSA:3.30.70.260 448 522 3.3E-16 T 09-03-2017 L21SP3_RS02670 7d097213173154c24b64db7edd3671bf 527 SUPERFAMILY SSF143548 323 450 1.54E-29 T 09-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 L21SP3_RS03505 fa507c5b23809e191f751f51d79cd21d 485 PRINTS PR01874 DNA repair protein radA signature 29 57 8.2E-6 T 09-03-2017 L21SP3_RS03505 fa507c5b23809e191f751f51d79cd21d 485 PRINTS PR01874 DNA repair protein radA signature 71 88 8.2E-6 T 09-03-2017 L21SP3_RS03505 fa507c5b23809e191f751f51d79cd21d 485 SUPERFAMILY SSF52540 20 243 1.64E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03505 fa507c5b23809e191f751f51d79cd21d 485 Pfam PF06745 KaiC 258 475 2.1E-40 T 09-03-2017 IPR014774 KaiC-like domain L21SP3_RS03505 fa507c5b23809e191f751f51d79cd21d 485 Pfam PF06745 KaiC 22 243 2.3E-56 T 09-03-2017 IPR014774 KaiC-like domain L21SP3_RS03505 fa507c5b23809e191f751f51d79cd21d 485 PIRSF PIRSF039117 5 485 2.9E-124 T 09-03-2017 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 L21SP3_RS03505 fa507c5b23809e191f751f51d79cd21d 485 SUPERFAMILY SSF52540 258 474 1.97E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03505 fa507c5b23809e191f751f51d79cd21d 485 Gene3D G3DSA:3.40.50.300 12 246 2.8E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03505 fa507c5b23809e191f751f51d79cd21d 485 Gene3D G3DSA:3.40.50.300 251 480 3.2E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 38 486 2.4E-176 T 09-03-2017 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101|MetaCyc: PWY-7230 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 427 1.6E-15 T 09-03-2017 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 189 1.6E-15 T 09-03-2017 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 455 462 1.6E-15 T 09-03-2017 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 334 1.6E-15 T 09-03-2017 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 Gene3D G3DSA:3.50.50.60 413 488 1.7E-13 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 187 1.3E-20 T 09-03-2017 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 412 428 1.3E-20 T 09-03-2017 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 309 327 1.3E-20 T 09-03-2017 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 440 462 1.3E-20 T 09-03-2017 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 SUPERFAMILY SSF51971 164 420 4.36E-65 T 09-03-2017 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 Gene3D G3DSA:3.40.50.720 169 257 1.1E-18 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 166 475 1.9E-36 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 SUPERFAMILY SSF46548 24 175 1.1E-35 T 09-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 SUPERFAMILY SSF51971 405 487 1.88E-9 T 09-03-2017 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 42 152 2.8E-38 T 09-03-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 Gene3D G3DSA:3.50.50.60 258 412 1.6E-47 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS06640 0d25574d6da61b23b99353d486ac448a 491 Gene3D G3DSA:1.10.1060.10 23 168 1.9E-45 T 09-03-2017 L21SP3_RS11110 457bd1bf768f50365fd4df07c1cf6458 242 Pfam PF04055 Radical SAM superfamily 24 179 1.8E-30 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS11110 457bd1bf768f50365fd4df07c1cf6458 242 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 6 235 2.4E-86 T 09-03-2017 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 L21SP3_RS11110 457bd1bf768f50365fd4df07c1cf6458 242 ProSitePatterns PS01087 Radical activating enzymes signature. 18 39 - T 09-03-2017 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 L21SP3_RS11110 457bd1bf768f50365fd4df07c1cf6458 242 SUPERFAMILY SSF102114 22 226 3.92E-30 T 09-03-2017 L21SP3_RS11110 457bd1bf768f50365fd4df07c1cf6458 242 Pfam PF13353 4Fe-4S single cluster domain 16 134 9.3E-21 T 09-03-2017 L21SP3_RS11110 457bd1bf768f50365fd4df07c1cf6458 242 Gene3D G3DSA:3.80.30.10 69 239 1.4E-60 T 09-03-2017 L21SP3_RS05135 3dbf85a317b0d7388862d9040da44530 404 Pfam PF00365 Phosphofructokinase 8 247 2.1E-41 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS05135 3dbf85a317b0d7388862d9040da44530 404 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 3 398 39.381 T 09-03-2017 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 L21SP3_RS05135 3dbf85a317b0d7388862d9040da44530 404 Gene3D G3DSA:3.40.50.450 5 229 4.7E-52 T 09-03-2017 L21SP3_RS05135 3dbf85a317b0d7388862d9040da44530 404 PIRSF PIRSF036483 2 402 2.7E-115 T 09-03-2017 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 L21SP3_RS05135 3dbf85a317b0d7388862d9040da44530 404 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 8 27 1.7E-9 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS05135 3dbf85a317b0d7388862d9040da44530 404 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 172 188 1.7E-9 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS05135 3dbf85a317b0d7388862d9040da44530 404 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 131 148 1.7E-9 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS05135 3dbf85a317b0d7388862d9040da44530 404 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 98 114 1.7E-9 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS05135 3dbf85a317b0d7388862d9040da44530 404 SUPERFAMILY SSF53784 5 389 1.57E-76 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS01085 d0fc6ade28c450dd7f754166c963195e 166 Pfam PF01230 HIT domain 41 134 3.9E-13 T 09-03-2017 IPR001310 Histidine triad (HIT) protein L21SP3_RS01085 d0fc6ade28c450dd7f754166c963195e 166 SUPERFAMILY SSF54197 8 152 2.63E-36 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 L21SP3_RS01085 d0fc6ade28c450dd7f754166c963195e 166 Gene3D G3DSA:3.30.428.10 26 164 3.4E-34 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 L21SP3_RS02805 405aa0d2a7477bec076f79ca7d9a029d 204 Pfam PF13649 Methyltransferase domain 56 152 3.0E-17 T 09-03-2017 L21SP3_RS02805 405aa0d2a7477bec076f79ca7d9a029d 204 Gene3D G3DSA:3.40.50.150 42 182 2.1E-27 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS02805 405aa0d2a7477bec076f79ca7d9a029d 204 SUPERFAMILY SSF53335 33 182 2.94E-29 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS00760 2203ab59d30ab27710a7b3e6e05dece9 1936 SUPERFAMILY SSF51445 1528 1776 1.98E-13 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS00760 2203ab59d30ab27710a7b3e6e05dece9 1936 Gene3D G3DSA:2.60.120.200 744 967 2.6E-24 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00760 2203ab59d30ab27710a7b3e6e05dece9 1936 Gene3D G3DSA:2.60.40.10 641 743 1.7E-8 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS00760 2203ab59d30ab27710a7b3e6e05dece9 1936 SUPERFAMILY SSF48726 651 742 1.57E-10 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS00760 2203ab59d30ab27710a7b3e6e05dece9 1936 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 821 965 4.5E-23 T 09-03-2017 L21SP3_RS00760 2203ab59d30ab27710a7b3e6e05dece9 1936 SMART SM00409 656 742 1.3E-5 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS00760 2203ab59d30ab27710a7b3e6e05dece9 1936 Gene3D G3DSA:2.70.70.10 336 448 5.6E-6 T 09-03-2017 L21SP3_RS00760 2203ab59d30ab27710a7b3e6e05dece9 1936 SMART SM00560 824 962 0.0016 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS00760 2203ab59d30ab27710a7b3e6e05dece9 1936 Gene3D G3DSA:3.20.20.80 1523 1789 1.4E-20 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS00760 2203ab59d30ab27710a7b3e6e05dece9 1936 SUPERFAMILY SSF49899 742 968 1.48E-27 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00760 2203ab59d30ab27710a7b3e6e05dece9 1936 Pfam PF07679 Immunoglobulin I-set domain 652 734 2.8E-5 T 09-03-2017 IPR013098 Immunoglobulin I-set L21SP3_RS08930 1dafb111484f5b9df17c5bce8e78e810 443 Pfam PF06123 Inner membrane protein CreD 16 439 4.1E-124 T 09-03-2017 IPR010364 Uncharacterised protein family, inner membrane CreD L21SP3_RS08930 1dafb111484f5b9df17c5bce8e78e810 443 PIRSF PIRSF004548 5 443 8.0E-117 T 09-03-2017 IPR010364 Uncharacterised protein family, inner membrane CreD L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 SUPERFAMILY SSF48452 372 471 1.14E-13 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 Gene3D G3DSA:1.25.40.10 247 329 1.0E-13 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 Pfam PF13181 Tetratricopeptide repeat 296 327 0.0076 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 Pfam PF13181 Tetratricopeptide repeat 406 435 0.1 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 Pfam PF13432 Tetratricopeptide repeat 131 190 1.9E-7 T 09-03-2017 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 Pfam PF13432 Tetratricopeptide repeat 208 262 2.7E-4 T 09-03-2017 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 SMART SM00028 439 472 3.2 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 SMART SM00028 126 159 4.1 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 SMART SM00028 194 227 0.18 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 SMART SM00028 228 261 230.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 SMART SM00028 160 193 0.0066 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 SMART SM00028 296 329 0.016 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 SMART SM00028 405 438 25.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 Gene3D G3DSA:1.25.40.10 130 246 4.2E-24 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 Gene3D G3DSA:1.25.40.10 367 471 3.6E-14 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS07600 dfb36ca37eb8884e8333955462fbca59 488 SUPERFAMILY SSF48452 103 329 1.02E-24 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS08730 844789500947cb13295c3a4fefe5f03d 470 SUPERFAMILY SSF53649 404 449 1.89E-99 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS08730 844789500947cb13295c3a4fefe5f03d 470 SUPERFAMILY SSF53649 33 367 1.89E-99 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS08730 844789500947cb13295c3a4fefe5f03d 470 Gene3D G3DSA:3.40.720.10 32 328 1.4E-73 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08730 844789500947cb13295c3a4fefe5f03d 470 Gene3D G3DSA:3.30.1120.10 406 454 6.9E-18 T 09-03-2017 L21SP3_RS08730 844789500947cb13295c3a4fefe5f03d 470 Gene3D G3DSA:3.30.1120.10 338 369 6.9E-18 T 09-03-2017 L21SP3_RS08730 844789500947cb13295c3a4fefe5f03d 470 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 23 0.0012 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal L21SP3_RS08730 844789500947cb13295c3a4fefe5f03d 470 Pfam PF00884 Sulfatase 34 308 4.2E-42 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS04020 8f9f486fc01e3eef8edf9d3708f28890 343 Pfam PF01595 Domain of unknown function DUF21 8 179 5.8E-32 T 09-03-2017 IPR002550 Domain of unknown function DUF21 L21SP3_RS04020 8f9f486fc01e3eef8edf9d3708f28890 343 Pfam PF00571 CBS domain 194 250 0.0039 T 09-03-2017 IPR000644 CBS domain L21SP3_RS04020 8f9f486fc01e3eef8edf9d3708f28890 343 Pfam PF00571 CBS domain 260 313 3.7E-6 T 09-03-2017 IPR000644 CBS domain L21SP3_RS04020 8f9f486fc01e3eef8edf9d3708f28890 343 Gene3D G3DSA:3.10.580.10 181 314 4.0E-17 T 09-03-2017 L21SP3_RS04020 8f9f486fc01e3eef8edf9d3708f28890 343 SUPERFAMILY SSF54631 182 314 4.09E-24 T 09-03-2017 L21SP3_RS05650 3f5246357ff2ea8a3ef1090323a5bccf 257 Gene3D G3DSA:3.20.20.70 6 255 1.6E-58 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS05650 3f5246357ff2ea8a3ef1090323a5bccf 257 Hamap MF_00443 Thiazole synthase [thiG]. 4 256 42.699 T 09-03-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 L21SP3_RS05650 3f5246357ff2ea8a3ef1090323a5bccf 257 Pfam PF05690 Thiazole biosynthesis protein ThiG 7 250 1.2E-106 T 09-03-2017 L21SP3_RS05650 3f5246357ff2ea8a3ef1090323a5bccf 257 SUPERFAMILY SSF110399 3 238 3.92E-80 T 09-03-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 L21SP3_RS06870 7104748b61993a6207e15c571c867d05 154 Gene3D G3DSA:3.40.390.30 3 141 2.5E-30 T 09-03-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 L21SP3_RS06870 7104748b61993a6207e15c571c867d05 154 SUPERFAMILY SSF55486 13 142 2.42E-26 T 09-03-2017 L21SP3_RS06870 7104748b61993a6207e15c571c867d05 154 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 5 143 15.879 T 09-03-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 L21SP3_RS06870 7104748b61993a6207e15c571c867d05 154 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 38 139 4.9E-22 T 09-03-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 L21SP3_RS06870 7104748b61993a6207e15c571c867d05 154 Pfam PF02130 Uncharacterized protein family UPF0054 20 139 7.4E-23 T 09-03-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 L21SP3_RS06905 eef853b3b5e5f3ada55d05f4760df0b3 95 SMART SM00883 2 94 2.9E-46 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS06905 eef853b3b5e5f3ada55d05f4760df0b3 95 PRINTS PR00297 10kDa chaperonin signature 3 18 1.2E-28 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS06905 eef853b3b5e5f3ada55d05f4760df0b3 95 PRINTS PR00297 10kDa chaperonin signature 81 94 1.2E-28 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS06905 eef853b3b5e5f3ada55d05f4760df0b3 95 PRINTS PR00297 10kDa chaperonin signature 60 72 1.2E-28 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS06905 eef853b3b5e5f3ada55d05f4760df0b3 95 PRINTS PR00297 10kDa chaperonin signature 25 46 1.2E-28 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS06905 eef853b3b5e5f3ada55d05f4760df0b3 95 SUPERFAMILY SSF50129 1 95 1.79E-32 T 09-03-2017 IPR011032 GroES-like L21SP3_RS06905 eef853b3b5e5f3ada55d05f4760df0b3 95 Gene3D G3DSA:2.30.33.40 1 95 1.3E-35 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS06905 eef853b3b5e5f3ada55d05f4760df0b3 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 24.834 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS06905 eef853b3b5e5f3ada55d05f4760df0b3 95 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 1.7E-33 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS06905 eef853b3b5e5f3ada55d05f4760df0b3 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 09-03-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 L21SP3_RS08240 95faf855ed2360e90b0133d6692cad57 490 Gene3D G3DSA:3.40.50.620 20 324 1.3E-101 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS08240 95faf855ed2360e90b0133d6692cad57 490 SMART SM00840 371 434 2.6E-15 T 09-03-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 L21SP3_RS08240 95faf855ed2360e90b0133d6692cad57 490 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 488 7.5E-156 T 09-03-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 L21SP3_RS08240 95faf855ed2360e90b0133d6692cad57 490 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.6E-24 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 L21SP3_RS08240 95faf855ed2360e90b0133d6692cad57 490 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 202 220 1.6E-24 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 L21SP3_RS08240 95faf855ed2360e90b0133d6692cad57 490 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 233 254 1.6E-24 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 L21SP3_RS08240 95faf855ed2360e90b0133d6692cad57 490 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.6E-24 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 L21SP3_RS08240 95faf855ed2360e90b0133d6692cad57 490 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 490 36.927 T 09-03-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 L21SP3_RS08240 95faf855ed2360e90b0133d6692cad57 490 SUPERFAMILY SSF47323 358 488 2.48E-28 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 L21SP3_RS08240 95faf855ed2360e90b0133d6692cad57 490 SUPERFAMILY SSF52374 3 331 1.31E-89 T 09-03-2017 L21SP3_RS08240 95faf855ed2360e90b0133d6692cad57 490 Gene3D G3DSA:1.20.120.640 326 424 5.9E-20 T 09-03-2017 L21SP3_RS08240 95faf855ed2360e90b0133d6692cad57 490 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 332 6.2E-110 T 09-03-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 L21SP3_RS08240 95faf855ed2360e90b0133d6692cad57 490 Pfam PF09190 DALR domain 371 428 5.3E-15 T 09-03-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 L21SP3_RS09580 aeaabdbe5ad9b942c54243aea7f4f505 157 SUPERFAMILY SSF54637 21 154 6.99E-30 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS09580 aeaabdbe5ad9b942c54243aea7f4f505 157 Gene3D G3DSA:3.10.129.10 19 155 7.2E-31 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS09580 aeaabdbe5ad9b942c54243aea7f4f505 157 Pfam PF07977 FabA-like domain 29 149 6.9E-24 T 09-03-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 L21SP3_RS11085 97de35a855de16d1a47284b7fe7b8491 170 Pfam PF09055 Nickel-containing superoxide dismutase 22 151 7.3E-30 T 09-03-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 L21SP3_RS11085 97de35a855de16d1a47284b7fe7b8491 170 SUPERFAMILY SSF109770 25 147 1.44E-7 T 09-03-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 L21SP3_RS11085 97de35a855de16d1a47284b7fe7b8491 170 Gene3D G3DSA:1.20.120.400 25 152 2.9E-25 T 09-03-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 L21SP3_RS07605 621e1424514c9231b076ec359d9a4d8a 221 SUPERFAMILY SSF74653 60 73 3.53E-18 T 09-03-2017 L21SP3_RS07605 621e1424514c9231b076ec359d9a4d8a 221 SUPERFAMILY SSF74653 121 219 3.53E-18 T 09-03-2017 L21SP3_RS07605 621e1424514c9231b076ec359d9a4d8a 221 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 151 218 5.3E-17 T 09-03-2017 IPR006260 TonB, C-terminal GO:0006810 L21SP3_RS07605 621e1424514c9231b076ec359d9a4d8a 221 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 151 218 7.5E-13 T 09-03-2017 IPR006260 TonB, C-terminal GO:0006810 L21SP3_RS07605 621e1424514c9231b076ec359d9a4d8a 221 Gene3D G3DSA:3.30.1150.10 135 220 9.7E-10 T 09-03-2017 L21SP3_RS02925 4dc72ce05bc733f0863197c43a707df0 362 Pfam PF02470 MlaD protein 37 138 1.5E-10 T 09-03-2017 IPR003399 Mce/MlaD L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 170 262 4.4E-30 T 09-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 Gene3D G3DSA:3.40.50.1010 4 180 3.5E-63 T 09-03-2017 IPR029060 PIN domain-like L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 Gene3D G3DSA:1.20.1060.10 536 651 1.0E-31 T 09-03-2017 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 SUPERFAMILY SSF53098 330 510 7.12E-49 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 PRINTS PR00868 DNA-polymerase family A (pol I) signature 834 850 7.4E-69 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 PRINTS PR00868 DNA-polymerase family A (pol I) signature 666 681 7.4E-69 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 PRINTS PR00868 DNA-polymerase family A (pol I) signature 689 712 7.4E-69 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 PRINTS PR00868 DNA-polymerase family A (pol I) signature 802 813 7.4E-69 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 PRINTS PR00868 DNA-polymerase family A (pol I) signature 864 877 7.4E-69 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 PRINTS PR00868 DNA-polymerase family A (pol I) signature 643 665 7.4E-69 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 PRINTS PR00868 DNA-polymerase family A (pol I) signature 780 791 7.4E-69 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 PRINTS PR00868 DNA-polymerase family A (pol I) signature 743 768 7.4E-69 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 PRINTS PR00868 DNA-polymerase family A (pol I) signature 719 732 7.4E-69 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 Gene3D G3DSA:1.10.150.20 701 806 4.3E-32 T 09-03-2017 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 SMART SM00482 674 881 4.6E-98 T 09-03-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 Gene3D G3DSA:1.10.150.20 181 241 1.6E-28 T 09-03-2017 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 TIGRFAM TIGR00593 pola: DNA polymerase I 6 915 1.2E-287 T 09-03-2017 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 Gene3D G3DSA:3.30.70.370 807 915 2.5E-65 T 09-03-2017 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 Gene3D G3DSA:3.30.70.370 652 700 2.5E-65 T 09-03-2017 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 ProSitePatterns PS00447 DNA polymerase family A signature. 743 762 - T 09-03-2017 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 SMART SM00474 325 510 2.0E-32 T 09-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 Gene3D G3DSA:3.30.420.10 323 534 4.6E-79 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 156 2.9E-48 T 09-03-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 Pfam PF00476 DNA polymerase family A 544 914 2.3E-144 T 09-03-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 SMART SM00475 1 259 3.2E-104 T 09-03-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 Pfam PF01612 3'-5' exonuclease 325 509 2.7E-35 T 09-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 SMART SM00279 171 206 2.7E-12 T 09-03-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 SUPERFAMILY SSF47807 169 282 4.19E-33 T 09-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 SUPERFAMILY SSF88723 3 163 2.09E-46 T 09-03-2017 IPR029060 PIN domain-like L21SP3_RS06420 54f18360bcd6f78b66a577a41d1fe426 917 SUPERFAMILY SSF56672 515 914 1.45E-142 T 09-03-2017 L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 SUPERFAMILY SSF51971 143 402 4.12E-67 T 09-03-2017 L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 131 6.3E-22 T 09-03-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 Gene3D G3DSA:3.40.50.720 148 234 8.3E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 Gene3D G3DSA:3.40.50.720 405 468 8.3E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 SUPERFAMILY SSF51971 371 465 7.06E-5 T 09-03-2017 L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 Gene3D G3DSA:1.10.1060.10 3 147 2.1E-39 T 09-03-2017 L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 Gene3D G3DSA:3.50.50.60 235 402 9.5E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 6.7E-24 T 09-03-2017 L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 6.7E-24 T 09-03-2017 L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 6.7E-24 T 09-03-2017 L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 6.7E-24 T 09-03-2017 L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 SUPERFAMILY SSF46548 4 155 5.23E-34 T 09-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 456 1.8E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS11305 612c168fcea0432f92ae7c6164042017 470 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 4 467 1.6E-191 T 09-03-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 L21SP3_RS05765 abc2e3b47617e1483b7371f2bee1bfd7 361 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 30 314 3.0E-24 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP3_RS05765 abc2e3b47617e1483b7371f2bee1bfd7 361 SUPERFAMILY SSF52540 148 356 9.88E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05765 abc2e3b47617e1483b7371f2bee1bfd7 361 SUPERFAMILY SSF52540 8 96 9.88E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05765 abc2e3b47617e1483b7371f2bee1bfd7 361 Gene3D G3DSA:3.40.50.300 8 63 6.6E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05765 abc2e3b47617e1483b7371f2bee1bfd7 361 Gene3D G3DSA:3.40.50.300 141 317 6.6E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03350 0bd8c04ae7e9bf69fe73153b57c15fb7 467 Gene3D G3DSA:1.10.275.10 1 137 8.3E-38 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal L21SP3_RS03350 0bd8c04ae7e9bf69fe73153b57c15fb7 467 Pfam PF10415 Fumarase C C-terminus 407 454 6.6E-10 T 09-03-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 L21SP3_RS03350 0bd8c04ae7e9bf69fe73153b57c15fb7 467 Gene3D G3DSA:1.10.40.30 417 454 8.2E-10 T 09-03-2017 L21SP3_RS03350 0bd8c04ae7e9bf69fe73153b57c15fb7 467 SUPERFAMILY SSF48557 2 454 1.49E-108 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 L21SP3_RS03350 0bd8c04ae7e9bf69fe73153b57c15fb7 467 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 1.5E-27 T 09-03-2017 IPR000362 Fumarate lyase family L21SP3_RS03350 0bd8c04ae7e9bf69fe73153b57c15fb7 467 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 1.5E-27 T 09-03-2017 IPR000362 Fumarate lyase family L21SP3_RS03350 0bd8c04ae7e9bf69fe73153b57c15fb7 467 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 1.5E-27 T 09-03-2017 IPR000362 Fumarate lyase family L21SP3_RS03350 0bd8c04ae7e9bf69fe73153b57c15fb7 467 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 1.5E-27 T 09-03-2017 IPR000362 Fumarate lyase family L21SP3_RS03350 0bd8c04ae7e9bf69fe73153b57c15fb7 467 Gene3D G3DSA:1.20.200.10 138 416 2.4E-74 T 09-03-2017 L21SP3_RS03350 0bd8c04ae7e9bf69fe73153b57c15fb7 467 Pfam PF00206 Lyase 11 340 2.2E-74 T 09-03-2017 IPR022761 Fumarate lyase, N-terminal L21SP3_RS03350 0bd8c04ae7e9bf69fe73153b57c15fb7 467 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 09-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 L21SP3_RS00545 95dc52f8f6a5161f77c9ad2e8d5cd44e 402 Pfam PF16325 Peptidase family U32 C-terminal domain 323 398 4.2E-13 T 09-03-2017 IPR032525 Peptidase family U32, C-terminal L21SP3_RS00545 95dc52f8f6a5161f77c9ad2e8d5cd44e 402 ProSitePatterns PS01276 Peptidase family U32 signature. 166 184 - T 09-03-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 L21SP3_RS00545 95dc52f8f6a5161f77c9ad2e8d5cd44e 402 Pfam PF01136 Peptidase family U32 80 305 3.9E-80 T 09-03-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 L21SP3_RS04460 b568d065b834c0f7fd6a2b2196b78490 472 SUPERFAMILY SSF47917 357 471 8.89E-46 T 09-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS04460 b568d065b834c0f7fd6a2b2196b78490 472 SMART SM00382 146 339 9.5E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS04460 b568d065b834c0f7fd6a2b2196b78490 472 SUPERFAMILY SSF52540 81 358 3.58E-85 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04460 b568d065b834c0f7fd6a2b2196b78490 472 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 134 354 3.9E-60 T 09-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS04460 b568d065b834c0f7fd6a2b2196b78490 472 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 77 6.5E-16 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS04460 b568d065b834c0f7fd6a2b2196b78490 472 SUPERFAMILY SSF50615 1 79 2.55E-21 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS04460 b568d065b834c0f7fd6a2b2196b78490 472 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 472 5.9E-226 T 09-03-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 L21SP3_RS04460 b568d065b834c0f7fd6a2b2196b78490 472 Gene3D G3DSA:3.40.50.300 81 356 3.5E-102 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04460 b568d065b834c0f7fd6a2b2196b78490 472 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 09-03-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS04460 b568d065b834c0f7fd6a2b2196b78490 472 Gene3D G3DSA:1.10.1140.10 357 470 1.9E-43 T 09-03-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS04460 b568d065b834c0f7fd6a2b2196b78490 472 Gene3D G3DSA:2.40.10.170 1 79 3.0E-23 T 09-03-2017 L21SP3_RS04460 b568d065b834c0f7fd6a2b2196b78490 472 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 472 53.43 T 09-03-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 L21SP3_RS07745 d8d3cb0ec5404010ea26703654745e6a 523 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 09-03-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 L21SP3_RS07745 d8d3cb0ec5404010ea26703654745e6a 523 Pfam PF00682 HMGL-like 3 274 3.0E-52 T 09-03-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 L21SP3_RS07745 d8d3cb0ec5404010ea26703654745e6a 523 Pfam PF08502 LeuA allosteric (dimerisation) domain 374 514 1.6E-25 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 L21SP3_RS07745 d8d3cb0ec5404010ea26703654745e6a 523 SUPERFAMILY SSF51569 2 293 2.2E-83 T 09-03-2017 L21SP3_RS07745 d8d3cb0ec5404010ea26703654745e6a 523 SUPERFAMILY SSF110921 394 511 8.63E-21 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 L21SP3_RS07745 d8d3cb0ec5404010ea26703654745e6a 523 Gene3D G3DSA:3.20.20.70 2 347 3.6E-123 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS07745 d8d3cb0ec5404010ea26703654745e6a 523 SMART SM00917 373 515 8.9E-33 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 L21SP3_RS07745 d8d3cb0ec5404010ea26703654745e6a 523 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 4 519 4.5E-222 T 09-03-2017 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 L21SP3_RS00020 95d524af6a12b14758d76b2edec37629 340 Gene3D G3DSA:3.20.20.210 1 330 3.9E-44 T 09-03-2017 L21SP3_RS00020 95d524af6a12b14758d76b2edec37629 340 SUPERFAMILY SSF51726 1 332 1.48E-40 T 09-03-2017 L21SP3_RS00020 95d524af6a12b14758d76b2edec37629 340 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 141 330 2.8E-27 T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 SUPERFAMILY SSF48600 2 89 4.88E-20 T 09-03-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 Pfam PF01817 Chorismate mutase type II 7 81 6.7E-21 T 09-03-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 Gene3D G3DSA:1.20.59.10 1 82 9.0E-21 T 09-03-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 SUPERFAMILY SSF53850 88 270 3.09E-56 T 09-03-2017 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 Gene3D G3DSA:3.40.190.10 173 250 7.9E-24 T 09-03-2017 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 300 307 - T 09-03-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 Pfam PF01842 ACT domain 275 338 2.0E-12 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 238 260 - T 09-03-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 TIGRFAM TIGR01807 CM_P2: chorismate mutase 3 77 3.6E-23 T 09-03-2017 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 Gene3D G3DSA:3.30.70.260 267 353 6.0E-32 T 09-03-2017 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 Pfam PF00800 Prephenate dehydratase 89 264 1.0E-57 T 09-03-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 Gene3D G3DSA:3.40.190.10 86 172 2.6E-30 T 09-03-2017 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 SUPERFAMILY SSF55021 257 352 1.44E-28 T 09-03-2017 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 SMART SM00830 7 87 4.2E-24 T 09-03-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 L21SP3_RS08680 6ce08274a25fdfc03150aa904db7d518 358 PIRSF PIRSF001500 1 354 1.5E-127 T 09-03-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 L21SP3_RS05100 8ce3d39524a4e9b957a8b1d957eb0a26 184 Gene3D G3DSA:3.30.420.10 88 156 1.9E-8 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS05100 8ce3d39524a4e9b957a8b1d957eb0a26 184 SUPERFAMILY SSF53098 88 156 1.11E-6 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS05100 8ce3d39524a4e9b957a8b1d957eb0a26 184 Pfam PF13276 HTH-like domain 23 78 6.2E-8 T 09-03-2017 IPR025948 HTH-like domain L21SP3_RS06865 b4ba8a1fd441127a0caff2b23a61d9b8 380 SUPERFAMILY SSF47819 299 378 5.42E-10 T 09-03-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 L21SP3_RS06865 b4ba8a1fd441127a0caff2b23a61d9b8 380 Pfam PF01612 3'-5' exonuclease 6 171 9.3E-32 T 09-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 L21SP3_RS06865 b4ba8a1fd441127a0caff2b23a61d9b8 380 Pfam PF00570 HRDC domain 309 375 3.0E-7 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 L21SP3_RS06865 b4ba8a1fd441127a0caff2b23a61d9b8 380 Pfam PF00570 HRDC domain 217 253 9.7E-6 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 L21SP3_RS06865 b4ba8a1fd441127a0caff2b23a61d9b8 380 SUPERFAMILY SSF53098 4 188 1.27E-51 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS06865 b4ba8a1fd441127a0caff2b23a61d9b8 380 SUPERFAMILY SSF47819 198 300 2.83E-11 T 09-03-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 L21SP3_RS06865 b4ba8a1fd441127a0caff2b23a61d9b8 380 SMART SM00474 6 172 7.7E-37 T 09-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 L21SP3_RS06865 b4ba8a1fd441127a0caff2b23a61d9b8 380 Gene3D G3DSA:3.30.420.10 5 177 7.3E-15 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS06865 b4ba8a1fd441127a0caff2b23a61d9b8 380 Gene3D G3DSA:1.10.150.80 306 377 1.4E-6 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 L21SP3_RS09225 6d3f6636b4182ed70c90cad0427c6dad 243 Pfam PF13419 Haloacid dehalogenase-like hydrolase 79 207 1.4E-15 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS09225 6d3f6636b4182ed70c90cad0427c6dad 243 Gene3D G3DSA:3.40.50.1000 2 237 2.5E-30 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS09225 6d3f6636b4182ed70c90cad0427c6dad 243 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 85 202 4.2E-8 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP3_RS09225 6d3f6636b4182ed70c90cad0427c6dad 243 SUPERFAMILY SSF56784 2 239 2.25E-29 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS06285 7b869bf1c9c7dfca78fe510357e35ed3 283 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 29 1.4E-4 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS06285 7b869bf1c9c7dfca78fe510357e35ed3 283 Gene3D G3DSA:3.30.700.10 10 73 6.4E-5 T 09-03-2017 L21SP3_RS06285 7b869bf1c9c7dfca78fe510357e35ed3 283 SUPERFAMILY SSF54523 10 75 2.35E-11 T 09-03-2017 L21SP3_RS06285 7b869bf1c9c7dfca78fe510357e35ed3 283 PRINTS PR00813 Bacterial general secretion pathway protein G signature 9 34 2.1E-5 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS06285 7b869bf1c9c7dfca78fe510357e35ed3 283 PRINTS PR00813 Bacterial general secretion pathway protein G signature 45 63 2.1E-5 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS10320 c5f55511315032b48f5703de0b62dc04 358 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 156 357 22.095 T 09-03-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 L21SP3_RS10320 c5f55511315032b48f5703de0b62dc04 358 Gene3D G3DSA:3.20.20.70 151 355 6.3E-57 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS10320 c5f55511315032b48f5703de0b62dc04 358 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 158 352 2.6E-48 T 09-03-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 L21SP3_RS10320 c5f55511315032b48f5703de0b62dc04 358 Pfam PF02581 Thiamine monophosphate synthase/TENI 162 339 1.7E-45 T 09-03-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 L21SP3_RS10320 c5f55511315032b48f5703de0b62dc04 358 SUPERFAMILY SSF51391 157 355 8.11E-53 T 09-03-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 L21SP3_RS02275 22518bd96e47f6beb2a01e0193e02cf8 874 SUPERFAMILY SSF75005 18 299 4.28E-72 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS02275 22518bd96e47f6beb2a01e0193e02cf8 874 Pfam PF04616 Glycosyl hydrolases family 43 32 298 1.3E-51 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS02275 22518bd96e47f6beb2a01e0193e02cf8 874 Gene3D G3DSA:2.115.10.20 26 311 1.2E-79 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS05280 4e3067f6728ffa8a82b5e5a185ee5251 232 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 155 206 1.0E-9 T 09-03-2017 IPR019264 Domain of unknown function DUF2179 L21SP3_RS05280 4e3067f6728ffa8a82b5e5a185ee5251 232 Hamap MF_01515 UPF0316 protein . 47 215 28.398 T 09-03-2017 IPR022930 Protein of unknown function UPF0316 L21SP3_RS00975 9a2a8245ec227137b7a184893ff36585 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 09-03-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 L21SP3_RS00975 9a2a8245ec227137b7a184893ff36585 194 SUPERFAMILY SSF54211 89 181 3.04E-33 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS00975 9a2a8245ec227137b7a184893ff36585 194 Gene3D G3DSA:3.30.230.40 92 194 5.0E-31 T 09-03-2017 L21SP3_RS00975 9a2a8245ec227137b7a184893ff36585 194 SUPERFAMILY SSF54211 4 88 3.41E-31 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold L21SP3_RS00975 9a2a8245ec227137b7a184893ff36585 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 33 175 2.1E-61 T 09-03-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 L21SP3_RS00975 9a2a8245ec227137b7a184893ff36585 194 Gene3D G3DSA:3.30.230.40 4 91 1.1E-36 T 09-03-2017 L21SP3_RS00975 9a2a8245ec227137b7a184893ff36585 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 4 194 39.934 T 09-03-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 L21SP3_RS00975 9a2a8245ec227137b7a184893ff36585 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 63 76 - T 09-03-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 L21SP3_RS08840 bf20ad56f4a30466dc27cb44f069a314 498 SUPERFAMILY SSF53649 35 187 2.76E-81 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS08840 bf20ad56f4a30466dc27cb44f069a314 498 SUPERFAMILY SSF53649 252 480 2.76E-81 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS08840 bf20ad56f4a30466dc27cb44f069a314 498 Gene3D G3DSA:3.40.720.10 34 144 2.4E-23 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08840 bf20ad56f4a30466dc27cb44f069a314 498 Gene3D G3DSA:3.30.1120.10 421 492 5.0E-17 T 09-03-2017 L21SP3_RS08840 bf20ad56f4a30466dc27cb44f069a314 498 Gene3D G3DSA:3.40.720.10 234 235 3.5E-36 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08840 bf20ad56f4a30466dc27cb44f069a314 498 Gene3D G3DSA:3.40.720.10 277 420 3.5E-36 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08840 bf20ad56f4a30466dc27cb44f069a314 498 Gene3D G3DSA:3.40.720.10 161 187 3.5E-36 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08840 bf20ad56f4a30466dc27cb44f069a314 498 Pfam PF00884 Sulfatase 36 379 7.9E-38 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS08840 bf20ad56f4a30466dc27cb44f069a314 498 Pfam PF16347 Domain of unknown function (DUF4976) 404 480 2.1E-10 T 09-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 L21SP3_RS04500 37ebeb326f58e2e5474262e466132555 704 SUPERFAMILY SSF69318 136 525 9.59E-30 T 09-03-2017 L21SP3_RS04500 37ebeb326f58e2e5474262e466132555 704 Gene3D G3DSA:2.130.10.130 137 417 2.0E-14 T 09-03-2017 L21SP3_RS04500 37ebeb326f58e2e5474262e466132555 704 SUPERFAMILY SSF47473 26 101 3.72E-11 T 09-03-2017 IPR011992 EF-hand domain pair L21SP3_RS04500 37ebeb326f58e2e5474262e466132555 704 ProSitePatterns PS00018 EF-hand calcium-binding domain. 60 72 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS04500 37ebeb326f58e2e5474262e466132555 704 Gene3D G3DSA:1.10.238.10 26 100 6.3E-9 T 09-03-2017 IPR011992 EF-hand domain pair L21SP3_RS04500 37ebeb326f58e2e5474262e466132555 704 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 322 415 1.3E-6 T 09-03-2017 L21SP3_RS04500 37ebeb326f58e2e5474262e466132555 704 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 195 255 3.4E-9 T 09-03-2017 L21SP3_RS04500 37ebeb326f58e2e5474262e466132555 704 ProSitePatterns PS00018 EF-hand calcium-binding domain. 34 46 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS04500 37ebeb326f58e2e5474262e466132555 704 Pfam PF13202 EF hand 59 76 0.04 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS00745 6b86824d4b16bdd03ed667aae84b9ac7 298 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 31 56 2.8E-9 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS00745 6b86824d4b16bdd03ed667aae84b9ac7 298 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 34 56 3.1E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS00745 6b86824d4b16bdd03ed667aae84b9ac7 298 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 35 55 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS00745 6b86824d4b16bdd03ed667aae84b9ac7 298 SUPERFAMILY SSF54523 37 133 2.98E-14 T 09-03-2017 L21SP3_RS00745 6b86824d4b16bdd03ed667aae84b9ac7 298 Gene3D G3DSA:3.30.700.10 37 76 2.1E-5 T 09-03-2017 L21SP3_RS08510 e1bf2f77fb68b34450f62071d9e62147 260 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 212 227 1.8E-5 T 09-03-2017 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP3_RS08510 e1bf2f77fb68b34450f62071d9e62147 260 PRINTS PR00813 Bacterial general secretion pathway protein G signature 7 32 6.3E-7 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS08510 e1bf2f77fb68b34450f62071d9e62147 260 PRINTS PR00813 Bacterial general secretion pathway protein G signature 43 61 6.3E-7 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS08510 e1bf2f77fb68b34450f62071d9e62147 260 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 4 27 8.4E-9 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS08510 e1bf2f77fb68b34450f62071d9e62147 260 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 28 5.5E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS08510 e1bf2f77fb68b34450f62071d9e62147 260 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS08510 e1bf2f77fb68b34450f62071d9e62147 260 Gene3D G3DSA:3.30.700.10 8 62 9.4E-5 T 09-03-2017 L21SP3_RS08510 e1bf2f77fb68b34450f62071d9e62147 260 SUPERFAMILY SSF54523 8 103 1.1E-14 T 09-03-2017 L21SP3_RS09185 6c9afc16bde8390d53eacabdc6a0c3e8 126 Gene3D G3DSA:3.90.1010.10 16 121 7.9E-9 T 09-03-2017 L21SP3_RS09185 6c9afc16bde8390d53eacabdc6a0c3e8 126 SUPERFAMILY SSF82649 17 120 7.33E-9 T 09-03-2017 L21SP3_RS09185 6c9afc16bde8390d53eacabdc6a0c3e8 126 Pfam PF01592 NifU-like N terminal domain 41 121 1.1E-5 T 09-03-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 L21SP3_RS10965 d022e6eb1b382252b05b68b2bb0004c8 210 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 27 165 5.1E-38 T 09-03-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 L21SP3_RS10965 d022e6eb1b382252b05b68b2bb0004c8 210 SUPERFAMILY SSF53335 19 167 1.09E-24 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS10965 d022e6eb1b382252b05b68b2bb0004c8 210 Gene3D G3DSA:3.40.50.150 37 173 4.5E-14 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS10965 d022e6eb1b382252b05b68b2bb0004c8 210 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 209 26.079 T 09-03-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 L21SP3_RS10965 d022e6eb1b382252b05b68b2bb0004c8 210 Pfam PF02390 Putative methyltransferase 32 193 8.7E-42 T 09-03-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 L21SP3_RS04580 976e2afb1b5198a168e18a579b915cf7 382 Gene3D G3DSA:2.120.10.10 37 381 1.1E-100 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS04580 976e2afb1b5198a168e18a579b915cf7 382 Pfam PF13088 BNR repeat-like domain 55 353 1.6E-42 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS04580 976e2afb1b5198a168e18a579b915cf7 382 SUPERFAMILY SSF50939 29 379 3.64E-107 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS09190 5e974f3167b1cfa75b5b3435f2bfa57b 291 Pfam PF14697 4Fe-4S dicluster domain 61 113 7.5E-11 T 09-03-2017 L21SP3_RS09190 5e974f3167b1cfa75b5b3435f2bfa57b 291 Gene3D G3DSA:3.30.70.20 74 107 3.6E-15 T 09-03-2017 L21SP3_RS09190 5e974f3167b1cfa75b5b3435f2bfa57b 291 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 98 109 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS09190 5e974f3167b1cfa75b5b3435f2bfa57b 291 Gene3D G3DSA:3.30.70.20 44 73 1.6E-7 T 09-03-2017 L21SP3_RS09190 5e974f3167b1cfa75b5b3435f2bfa57b 291 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 256 4.4E-29 T 09-03-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain L21SP3_RS09190 5e974f3167b1cfa75b5b3435f2bfa57b 291 SUPERFAMILY SSF54862 58 116 5.02E-16 T 09-03-2017 L21SP3_RS09190 5e974f3167b1cfa75b5b3435f2bfa57b 291 SUPERFAMILY SSF52540 114 287 4.02E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09190 5e974f3167b1cfa75b5b3435f2bfa57b 291 SUPERFAMILY SSF52540 4 60 4.02E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09190 5e974f3167b1cfa75b5b3435f2bfa57b 291 Gene3D G3DSA:3.40.50.300 108 286 1.6E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09190 5e974f3167b1cfa75b5b3435f2bfa57b 291 Gene3D G3DSA:3.40.50.300 1 43 1.6E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01540 605f0cc5bd546c4a95843d0c92ef2901 497 TIGRFAM TIGR03955 rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG 23 496 1.1E-133 T 09-03-2017 IPR024007 [FeFe]-hydrogenase maturation HydG, radical SAM L21SP3_RS01540 605f0cc5bd546c4a95843d0c92ef2901 497 SUPERFAMILY SSF102114 61 376 1.05E-41 T 09-03-2017 L21SP3_RS01540 605f0cc5bd546c4a95843d0c92ef2901 497 Pfam PF04055 Radical SAM superfamily 108 270 4.8E-8 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS01540 605f0cc5bd546c4a95843d0c92ef2901 497 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 295 403 4.9E-15 T 09-03-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 L21SP3_RS01540 605f0cc5bd546c4a95843d0c92ef2901 497 SMART SM00876 295 405 1.3E-12 T 09-03-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 L21SP3_RS01540 605f0cc5bd546c4a95843d0c92ef2901 497 Gene3D G3DSA:3.20.20.70 60 357 2.9E-41 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS07135 315a9a12d684b931dc598363e2062ce7 537 PIRSF PIRSF000414 1 537 1.4E-198 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 L21SP3_RS07135 315a9a12d684b931dc598363e2062ce7 537 SMART SM00851 17 132 2.0E-55 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain L21SP3_RS07135 315a9a12d684b931dc598363e2062ce7 537 Gene3D G3DSA:3.40.140.20 249 375 2.1E-34 T 09-03-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 L21SP3_RS07135 315a9a12d684b931dc598363e2062ce7 537 SMART SM00798 137 472 2.2E-140 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 L21SP3_RS07135 315a9a12d684b931dc598363e2062ce7 537 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 6 537 4.3E-191 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 L21SP3_RS07135 315a9a12d684b931dc598363e2062ce7 537 SUPERFAMILY SSF53927 211 537 2.31E-104 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 L21SP3_RS07135 315a9a12d684b931dc598363e2062ce7 537 Gene3D G3DSA:3.40.140.20 387 527 6.5E-48 T 09-03-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 L21SP3_RS07135 315a9a12d684b931dc598363e2062ce7 537 SUPERFAMILY SSF52335 5 197 7.63E-69 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain L21SP3_RS07135 315a9a12d684b931dc598363e2062ce7 537 Gene3D G3DSA:3.40.50.1380 4 190 1.0E-82 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain L21SP3_RS07135 315a9a12d684b931dc598363e2062ce7 537 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 5 537 41.2 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 L21SP3_RS07135 315a9a12d684b931dc598363e2062ce7 537 Pfam PF02142 MGS-like domain 18 131 6.1E-29 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain L21SP3_RS07135 315a9a12d684b931dc598363e2062ce7 537 Pfam PF01808 AICARFT/IMPCHase bienzyme 137 469 3.8E-98 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 L21SP3_RS01660 eb7e220790f1fe70538fade44a64d8c8 455 Gene3D G3DSA:2.60.120.380 176 289 2.4E-4 T 09-03-2017 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 PIRSF PIRSF000532 4 367 3.1E-115 T 09-03-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 SUPERFAMILY SSF53784 2 360 1.96E-113 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 ProSitePatterns PS00433 Phosphofructokinase signature. 286 304 - T 09-03-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 103 119 3.3E-62 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 168 184 3.3E-62 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 186 203 3.3E-62 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 10 29 3.3E-62 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 148 166 3.3E-62 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 35 48 3.3E-62 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 130 147 3.3E-62 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 282 304 3.3E-62 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 6 367 38.25 T 09-03-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 Gene3D G3DSA:3.40.50.450 3 222 2.0E-70 T 09-03-2017 L21SP3_RS03405 f248836e7ea4c752e9937e237b768a9c 372 Pfam PF00365 Phosphofructokinase 8 316 4.1E-97 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 L21SP3_RS10825 1863ff25b18bf9b26beb37ffa3148e9a 226 Gene3D G3DSA:3.30.559.10 2 224 2.5E-49 T 09-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 L21SP3_RS10825 1863ff25b18bf9b26beb37ffa3148e9a 226 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 2 224 4.7E-47 T 09-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 L21SP3_RS10825 1863ff25b18bf9b26beb37ffa3148e9a 226 SUPERFAMILY SSF52777 2 224 6.67E-49 T 09-03-2017 L21SP3_RS04250 1337d2b4c54bf265bde3406c4b211d5d 168 Pfam PF03061 Thioesterase superfamily 56 139 9.2E-13 T 09-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 L21SP3_RS04250 1337d2b4c54bf265bde3406c4b211d5d 168 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 49 161 3.2E-24 T 09-03-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 L21SP3_RS04250 1337d2b4c54bf265bde3406c4b211d5d 168 Gene3D G3DSA:3.10.129.10 38 165 2.3E-35 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS04250 1337d2b4c54bf265bde3406c4b211d5d 168 SUPERFAMILY SSF54637 40 164 1.41E-33 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS04360 57bbef95863952c791e4d5fa8b75c302 313 Pfam PF04015 Domain of unknown function (DUF362) 41 237 9.2E-33 T 09-03-2017 IPR007160 Domain of unknown function DUF362 L21SP3_RS10610 5e13f3e492bdd8a6eb1f99c892d4998c 309 Pfam PF01180 Dihydroorotate dehydrogenase 8 291 3.4E-68 T 09-03-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 L21SP3_RS10610 5e13f3e492bdd8a6eb1f99c892d4998c 309 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 8 306 1.2E-97 T 09-03-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 L21SP3_RS10610 5e13f3e492bdd8a6eb1f99c892d4998c 309 SUPERFAMILY SSF51395 4 308 1.83E-74 T 09-03-2017 L21SP3_RS10610 5e13f3e492bdd8a6eb1f99c892d4998c 309 Gene3D G3DSA:3.20.20.70 7 307 4.2E-82 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS10610 5e13f3e492bdd8a6eb1f99c892d4998c 309 PIRSF PIRSF000164 3 309 1.7E-70 T 09-03-2017 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 L21SP3_RS10610 5e13f3e492bdd8a6eb1f99c892d4998c 309 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 6 308 37.686 T 09-03-2017 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 L21SP3_RS10610 5e13f3e492bdd8a6eb1f99c892d4998c 309 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 246 266 - T 09-03-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 L21SP3_RS10610 5e13f3e492bdd8a6eb1f99c892d4998c 309 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 42 61 - T 09-03-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 L21SP3_RS04505 7fd07910797293770c17e834da22a655 680 SUPERFAMILY SSF69318 428 666 8.76E-22 T 09-03-2017 L21SP3_RS04505 7fd07910797293770c17e834da22a655 680 SUPERFAMILY SSF53474 101 277 1.26E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS04505 7fd07910797293770c17e834da22a655 680 SUPERFAMILY SSF53474 326 383 1.26E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS04505 7fd07910797293770c17e834da22a655 680 Gene3D G3DSA:2.130.10.130 427 663 3.1E-12 T 09-03-2017 L21SP3_RS04505 7fd07910797293770c17e834da22a655 680 Gene3D G3DSA:3.40.50.1820 81 388 1.9E-43 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS04505 7fd07910797293770c17e834da22a655 680 Pfam PF10503 Esterase PHB depolymerase 114 252 1.2E-12 T 09-03-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 L21SP3_RS00410 93d5edcf452caf18a4728494a23314fb 93 SUPERFAMILY SSF51182 26 90 5.86E-13 T 09-03-2017 IPR011051 RmlC-like cupin domain L21SP3_RS00410 93d5edcf452caf18a4728494a23314fb 93 Pfam PF05899 Protein of unknown function (DUF861) 23 90 1.1E-17 T 09-03-2017 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 L21SP3_RS00410 93d5edcf452caf18a4728494a23314fb 93 Gene3D G3DSA:2.60.120.10 23 92 2.2E-21 T 09-03-2017 IPR014710 RmlC-like jelly roll fold L21SP3_RS10620 5a7f8d904aa72eaa2e5a646c7b714d23 330 SUPERFAMILY SSF53098 175 321 1.29E-25 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS10620 5a7f8d904aa72eaa2e5a646c7b714d23 330 Gene3D G3DSA:3.30.420.10 176 322 3.7E-14 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS10620 5a7f8d904aa72eaa2e5a646c7b714d23 330 ProSitePatterns PS01043 Transposases, IS30 family, signature. 268 284 - T 09-03-2017 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 L21SP3_RS10620 5a7f8d904aa72eaa2e5a646c7b714d23 330 Pfam PF13936 Helix-turn-helix domain 3 45 4.9E-14 T 09-03-2017 IPR025246 Transposase IS30-like HTH domain L21SP3_RS10620 5a7f8d904aa72eaa2e5a646c7b714d23 330 Pfam PF00665 Integrase core domain 178 280 8.0E-13 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS00475 5a7f8d904aa72eaa2e5a646c7b714d23 330 SUPERFAMILY SSF53098 175 321 1.29E-25 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS00475 5a7f8d904aa72eaa2e5a646c7b714d23 330 Gene3D G3DSA:3.30.420.10 176 322 3.7E-14 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS00475 5a7f8d904aa72eaa2e5a646c7b714d23 330 ProSitePatterns PS01043 Transposases, IS30 family, signature. 268 284 - T 09-03-2017 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 L21SP3_RS00475 5a7f8d904aa72eaa2e5a646c7b714d23 330 Pfam PF13936 Helix-turn-helix domain 3 45 4.9E-14 T 09-03-2017 IPR025246 Transposase IS30-like HTH domain L21SP3_RS00475 5a7f8d904aa72eaa2e5a646c7b714d23 330 Pfam PF00665 Integrase core domain 178 280 8.0E-13 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 Pfam PF01411 tRNA synthetases class II (A) 6 567 8.8E-211 T 09-03-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 SUPERFAMILY SSF55681 3 258 1.84E-98 T 09-03-2017 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 Pfam PF02272 DHHA1 domain 828 895 1.7E-14 T 09-03-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 665 716 1.3E-17 T 09-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 SUPERFAMILY SSF55186 569 729 1.57E-45 T 09-03-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 PRINTS PR00980 Alanyl-tRNA synthetase signature 239 252 8.3E-30 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 PRINTS PR00980 Alanyl-tRNA synthetase signature 75 86 8.3E-30 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 PRINTS PR00980 Alanyl-tRNA synthetase signature 315 328 8.3E-30 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 PRINTS PR00980 Alanyl-tRNA synthetase signature 212 223 8.3E-30 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 PRINTS PR00980 Alanyl-tRNA synthetase signature 291 307 8.3E-30 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 SUPERFAMILY SSF101353 259 452 3.53E-66 T 09-03-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 901 165.278 T 09-03-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 Gene3D G3DSA:3.30.930.10 2 254 1.5E-108 T 09-03-2017 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 SUPERFAMILY SSF50447 498 565 1.2E-12 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 880 1.0E-290 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 L21SP3_RS03220 f633252ac148a8d8901054818dcea846 902 SMART SM00863 665 717 2.9E-19 T 09-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 L21SP3_RS06250 bb7338010e13e950dc10b42ed7fae126 404 Gene3D G3DSA:3.90.550.10 117 258 2.5E-12 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS06250 bb7338010e13e950dc10b42ed7fae126 404 SUPERFAMILY SSF53448 44 273 1.69E-22 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS06250 bb7338010e13e950dc10b42ed7fae126 404 Pfam PF13641 Glycosyltransferase like family 2 45 268 1.9E-14 T 09-03-2017 L21SP3_RS06050 3250530a3d6f106141e62c1af167920a 419 SUPERFAMILY SSF51658 4 419 5.41E-76 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP3_RS06050 3250530a3d6f106141e62c1af167920a 419 Gene3D G3DSA:3.20.20.150 4 419 1.4E-202 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain L21SP3_RS06050 3250530a3d6f106141e62c1af167920a 419 TIGRFAM TIGR01748 rhaA: L-rhamnose isomerase 5 419 8.6E-199 T 09-03-2017 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 L21SP3_RS06050 3250530a3d6f106141e62c1af167920a 419 Pfam PF06134 L-rhamnose isomerase (RhaA) 4 419 3.6E-203 T 09-03-2017 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 L21SP3_RS06050 3250530a3d6f106141e62c1af167920a 419 Hamap MF_00541 L-rhamnose isomerase [rhaA]. 1 419 233.306 T 09-03-2017 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 L21SP3_RS06050 3250530a3d6f106141e62c1af167920a 419 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 9 419 2.0E-152 T 09-03-2017 L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 SUPERFAMILY SSF51246 326 421 4.24E-30 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 5.0E-36 T 09-03-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 Gene3D G3DSA:3.90.600.10 328 420 4.7E-36 T 09-03-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 Gene3D G3DSA:3.30.470.20 190 325 4.2E-59 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 421 2.7E-168 T 09-03-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 1.8E-75 T 09-03-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 SMART SM01210 327 421 8.3E-51 T 09-03-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 328 418 1.9E-30 T 09-03-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 SUPERFAMILY SSF52440 1 100 1.87E-35 T 09-03-2017 IPR016185 Pre-ATP-grasp domain L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 SMART SM01209 101 293 3.8E-113 T 09-03-2017 L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 Gene3D G3DSA:3.30.1490.20 119 188 1.0E-22 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 421 41.654 T 09-03-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 Gene3D G3DSA:3.40.50.20 2 93 9.3E-37 T 09-03-2017 IPR016185 Pre-ATP-grasp domain L21SP3_RS00620 d56ea216d0cfc9e666aa7c6b5b6cb578 422 SUPERFAMILY SSF56059 102 320 9.55E-59 T 09-03-2017 L21SP3_RS05655 4d4920e77a3af5959a3e01117dfa409f 378 Gene3D G3DSA:3.20.20.70 44 369 6.2E-49 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS05655 4d4920e77a3af5959a3e01117dfa409f 378 SUPERFAMILY SSF102114 41 369 2.49E-50 T 09-03-2017 L21SP3_RS05655 4d4920e77a3af5959a3e01117dfa409f 378 Pfam PF04055 Radical SAM superfamily 85 230 3.3E-13 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS05655 4d4920e77a3af5959a3e01117dfa409f 378 SMART SM00876 261 367 5.7E-28 T 09-03-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 L21SP3_RS05655 4d4920e77a3af5959a3e01117dfa409f 378 TIGRFAM TIGR02351 thiH: thiazole biosynthesis protein ThiH 22 374 6.1E-127 T 09-03-2017 IPR012726 Thiazole biosynthesis ThiH GO:0005506|GO:0009228|GO:0051539 KEGG: 00730+4.1.99.19|MetaCyc: PWY-6892 L21SP3_RS05655 4d4920e77a3af5959a3e01117dfa409f 378 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 261 366 1.7E-24 T 09-03-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 L21SP3_RS05655 4d4920e77a3af5959a3e01117dfa409f 378 SMART SM00729 79 291 0.005 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP3_RS02460 8c65f12474f1fe6823e8191735abdac6 363 PIRSF PIRSF000524 1 363 3.4E-98 T 09-03-2017 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 L21SP3_RS02460 8c65f12474f1fe6823e8191735abdac6 363 Pfam PF00266 Aminotransferase class-V 12 325 5.6E-34 T 09-03-2017 IPR000192 Aminotransferase class V domain L21SP3_RS02460 8c65f12474f1fe6823e8191735abdac6 363 Gene3D G3DSA:3.90.1150.10 260 360 1.0E-25 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS02460 8c65f12474f1fe6823e8191735abdac6 363 SUPERFAMILY SSF53383 6 361 7.94E-86 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS02460 8c65f12474f1fe6823e8191735abdac6 363 Gene3D G3DSA:3.40.640.10 20 259 9.4E-47 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS08270 e5540ca4fba7517fb10f8dff509b9eb0 166 Pfam PF11149 Protein of unknown function (DUF2924) 9 160 7.9E-40 T 09-03-2017 IPR021322 Protein of unknown function DUF2924 L21SP3_RS02430 a362bfe8b39acbaa331731f187cdf13a 309 Pfam PF02445 Quinolinate synthetase A protein 6 296 3.0E-118 T 09-03-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 L21SP3_RS02430 a362bfe8b39acbaa331731f187cdf13a 309 Hamap MF_00568 Quinolinate synthase A [nadA]. 1 298 43.788 T 09-03-2017 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 L21SP3_RS02430 a362bfe8b39acbaa331731f187cdf13a 309 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 3 298 2.3E-108 T 09-03-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 L21SP3_RS02430 a362bfe8b39acbaa331731f187cdf13a 309 SUPERFAMILY SSF142754 2 297 4.05E-112 T 09-03-2017 L21SP3_RS06075 8d612eb6fe39eaa7d1269e82061f6ca7 192 SUPERFAMILY SSF64263 1 134 9.03E-39 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06075 8d612eb6fe39eaa7d1269e82061f6ca7 192 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06075 8d612eb6fe39eaa7d1269e82061f6ca7 192 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 132 9.3E-36 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06075 8d612eb6fe39eaa7d1269e82061f6ca7 192 Gene3D G3DSA:3.90.1030.10 1 132 2.0E-41 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06075 8d612eb6fe39eaa7d1269e82061f6ca7 192 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 131 24.827 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06075 8d612eb6fe39eaa7d1269e82061f6ca7 192 Pfam PF01196 Ribosomal protein L17 20 131 2.4E-31 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS09875 5d1fb3cd01eb5f5a7b0924c037f90604 803 Pfam PF13567 Domain of unknown function (DUF4131) 41 217 1.0E-16 T 09-03-2017 IPR025405 Domain of unknown function DUF4131 L21SP3_RS09875 5d1fb3cd01eb5f5a7b0924c037f90604 803 SUPERFAMILY SSF56281 569 791 2.3E-26 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS09875 5d1fb3cd01eb5f5a7b0924c037f90604 803 Pfam PF03772 Competence protein 257 538 1.2E-46 T 09-03-2017 IPR004477 ComEC/Rec2-related protein L21SP3_RS09875 5d1fb3cd01eb5f5a7b0924c037f90604 803 Gene3D G3DSA:3.60.15.10 573 762 5.9E-12 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS09875 5d1fb3cd01eb5f5a7b0924c037f90604 803 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 279 467 1.4E-15 T 09-03-2017 IPR004477 ComEC/Rec2-related protein L21SP3_RS09875 5d1fb3cd01eb5f5a7b0924c037f90604 803 Pfam PF00753 Metallo-beta-lactamase superfamily 581 721 5.3E-6 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS10520 f16988b09b83faa1b5c45aee75e4ad92 965 PRINTS PR00738 Glycosyl hydrolase family 20 signature 433 450 1.0E-5 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS10520 f16988b09b83faa1b5c45aee75e4ad92 965 PRINTS PR00738 Glycosyl hydrolase family 20 signature 569 582 1.0E-5 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS10520 f16988b09b83faa1b5c45aee75e4ad92 965 PRINTS PR00738 Glycosyl hydrolase family 20 signature 398 418 1.0E-5 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS10520 f16988b09b83faa1b5c45aee75e4ad92 965 Gene3D G3DSA:3.20.20.80 698 712 4.2E-19 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS10520 f16988b09b83faa1b5c45aee75e4ad92 965 Gene3D G3DSA:3.20.20.80 424 666 4.2E-19 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS10520 f16988b09b83faa1b5c45aee75e4ad92 965 SUPERFAMILY SSF55545 294 437 8.11E-18 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS10520 f16988b09b83faa1b5c45aee75e4ad92 965 SUPERFAMILY SSF51445 460 748 9.83E-26 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS10520 f16988b09b83faa1b5c45aee75e4ad92 965 Gene3D G3DSA:3.30.379.10 276 423 2.5E-18 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS10520 f16988b09b83faa1b5c45aee75e4ad92 965 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 295 436 1.7E-13 T 09-03-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 1.0E-25 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 47 66 1.0E-25 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 1.0E-25 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 131 142 1.0E-25 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 143 2.1E-43 T 09-03-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 45 59 5.9E-27 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 220 230 5.9E-27 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 80 93 5.9E-27 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 120 134 5.9E-27 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 282 293 5.9E-27 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 301 6.0E-54 T 09-03-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 303 7.3E-112 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 SUPERFAMILY SSF53671 1 303 2.1E-99 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 Gene3D G3DSA:3.40.50.1370 141 290 7.2E-61 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 1 304 71.03 T 09-03-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 L21SP3_RS04205 0a2893f6ec10d32a173940e56ddee33b 305 Gene3D G3DSA:3.40.50.1370 1 140 3.3E-47 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 L21SP3_RS02600 c687e076c4d9b6061501ee01383a01c4 413 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 142 410 1.1E-54 T 09-03-2017 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 L21SP3_RS02600 c687e076c4d9b6061501ee01383a01c4 413 Pfam PF08486 Stage II sporulation protein 137 225 5.9E-22 T 09-03-2017 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal L21SP3_RS00770 9b602d29a6507adccfd08ecf7eec783b 386 SUPERFAMILY SSF46689 329 379 1.93E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS00770 9b602d29a6507adccfd08ecf7eec783b 386 Pfam PF12833 Helix-turn-helix domain 301 378 4.9E-15 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS00770 9b602d29a6507adccfd08ecf7eec783b 386 Gene3D G3DSA:1.10.10.60 275 329 2.4E-7 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS00770 9b602d29a6507adccfd08ecf7eec783b 386 Gene3D G3DSA:1.10.10.60 330 380 2.2E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS00770 9b602d29a6507adccfd08ecf7eec783b 386 Gene3D G3DSA:3.40.50.2300 54 108 1.5E-5 T 09-03-2017 L21SP3_RS00770 9b602d29a6507adccfd08ecf7eec783b 386 Pfam PF13377 Periplasmic binding protein-like domain 108 269 4.3E-27 T 09-03-2017 L21SP3_RS00770 9b602d29a6507adccfd08ecf7eec783b 386 Gene3D G3DSA:3.40.50.2300 109 270 2.3E-25 T 09-03-2017 L21SP3_RS00770 9b602d29a6507adccfd08ecf7eec783b 386 SMART SM00342 293 376 4.3E-17 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS00770 9b602d29a6507adccfd08ecf7eec783b 386 SUPERFAMILY SSF53822 54 293 6.83E-28 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS08455 151f115fc51642d8a0b61b8d46a6b66c 218 SUPERFAMILY SSF53335 13 153 1.45E-11 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08455 151f115fc51642d8a0b61b8d46a6b66c 218 Gene3D G3DSA:3.40.50.150 134 144 2.7E-11 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08455 151f115fc51642d8a0b61b8d46a6b66c 218 Gene3D G3DSA:3.40.50.150 19 102 2.7E-11 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS04375 a6cd145d29ae164e95ebbd1d2f9db3e4 369 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 14 125 4.8E-5 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 L21SP3_RS04375 a6cd145d29ae164e95ebbd1d2f9db3e4 369 Gene3D G3DSA:3.40.50.720 10 148 2.5E-14 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04375 a6cd145d29ae164e95ebbd1d2f9db3e4 369 SUPERFAMILY SSF51735 13 150 3.45E-18 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04375 a6cd145d29ae164e95ebbd1d2f9db3e4 369 Gene3D G3DSA:3.30.360.10 156 351 6.9E-9 T 09-03-2017 L21SP3_RS10080 a63f635fd231ec1dfe6b3933fa66e0a9 773 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 61 211 6.0E-18 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS10080 a63f635fd231ec1dfe6b3933fa66e0a9 773 SUPERFAMILY SSF49785 45 217 5.1E-47 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10080 a63f635fd231ec1dfe6b3933fa66e0a9 773 Gene3D G3DSA:2.60.120.260 45 207 9.0E-53 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10080 a63f635fd231ec1dfe6b3933fa66e0a9 773 SUPERFAMILY SSF49303 243 314 7.48E-11 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS10080 a63f635fd231ec1dfe6b3933fa66e0a9 773 Gene3D G3DSA:3.20.20.80 314 533 1.3E-40 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS10080 a63f635fd231ec1dfe6b3933fa66e0a9 773 Gene3D G3DSA:3.20.20.80 568 625 1.3E-40 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS10080 a63f635fd231ec1dfe6b3933fa66e0a9 773 Gene3D G3DSA:2.60.40.320 208 313 8.9E-19 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS10080 a63f635fd231ec1dfe6b3933fa66e0a9 773 SUPERFAMILY SSF51445 312 616 4.06E-48 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS10080 a63f635fd231ec1dfe6b3933fa66e0a9 773 Pfam PF00703 Glycosyl hydrolases family 2 264 314 1.5E-8 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS00465 4fe35043d03df67f8450774a72480143 786 Gene3D G3DSA:3.60.10.10 534 782 2.9E-22 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase L21SP3_RS00465 4fe35043d03df67f8450774a72480143 786 SUPERFAMILY SSF56219 542 782 2.36E-38 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase L21SP3_RS00465 4fe35043d03df67f8450774a72480143 786 SUPERFAMILY SSF53649 242 495 7.72E-7 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS00465 4fe35043d03df67f8450774a72480143 786 SUPERFAMILY SSF53649 33 118 7.72E-7 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS00465 4fe35043d03df67f8450774a72480143 786 SUPERFAMILY SSF53649 154 180 7.72E-7 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS00465 4fe35043d03df67f8450774a72480143 786 Gene3D G3DSA:3.40.720.10 24 122 5.5E-6 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS00465 4fe35043d03df67f8450774a72480143 786 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 550 775 1.3E-20 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase L21SP3_RS05445 de20d3b948fce0a8e8dbb0d931839bb3 279 Gene3D G3DSA:1.10.3720.10 81 268 1.5E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS05445 de20d3b948fce0a8e8dbb0d931839bb3 279 SUPERFAMILY SSF161098 85 269 5.49E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS05445 de20d3b948fce0a8e8dbb0d931839bb3 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 264 4.6E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS06995 e1c5a93049a2f6db63e85be798c56476 487 SUPERFAMILY SSF54631 66 205 1.06E-27 T 09-03-2017 L21SP3_RS06995 e1c5a93049a2f6db63e85be798c56476 487 PIRSF PIRSF000130 1 486 1.1E-202 T 09-03-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 L21SP3_RS06995 e1c5a93049a2f6db63e85be798c56476 487 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 11 453 1.1E-183 T 09-03-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 L21SP3_RS06995 e1c5a93049a2f6db63e85be798c56476 487 Pfam PF00571 CBS domain 152 202 2.2E-6 T 09-03-2017 IPR000644 CBS domain L21SP3_RS06995 e1c5a93049a2f6db63e85be798c56476 487 Pfam PF00571 CBS domain 99 142 9.6E-10 T 09-03-2017 IPR000644 CBS domain L21SP3_RS06995 e1c5a93049a2f6db63e85be798c56476 487 SMART SM00116 160 207 4.0E-6 T 09-03-2017 IPR000644 CBS domain L21SP3_RS06995 e1c5a93049a2f6db63e85be798c56476 487 SMART SM00116 99 147 2.0E-10 T 09-03-2017 IPR000644 CBS domain L21SP3_RS06995 e1c5a93049a2f6db63e85be798c56476 487 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 11 485 80.687 T 09-03-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 L21SP3_RS06995 e1c5a93049a2f6db63e85be798c56476 487 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 11 472 8.7E-158 T 09-03-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 L21SP3_RS06995 e1c5a93049a2f6db63e85be798c56476 487 SMART SM01240 10 472 1.9E-292 T 09-03-2017 L21SP3_RS06995 e1c5a93049a2f6db63e85be798c56476 487 Gene3D G3DSA:3.20.20.70 6 484 9.0E-187 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS06995 e1c5a93049a2f6db63e85be798c56476 487 SUPERFAMILY SSF51412 218 476 1.7E-119 T 09-03-2017 L21SP3_RS06995 e1c5a93049a2f6db63e85be798c56476 487 SUPERFAMILY SSF51412 6 93 1.7E-119 T 09-03-2017 L21SP3_RS08700 3b8d6f59d9944d5fa330cbf5a9af9f45 184 Pfam PF00625 Guanylate kinase 5 183 7.0E-46 T 09-03-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit L21SP3_RS08700 3b8d6f59d9944d5fa330cbf5a9af9f45 184 Hamap MF_00328 Guanylate kinase [gmk]. 3 184 31.817 T 09-03-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 L21SP3_RS08700 3b8d6f59d9944d5fa330cbf5a9af9f45 184 SUPERFAMILY SSF52540 3 183 2.82E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08700 3b8d6f59d9944d5fa330cbf5a9af9f45 184 Gene3D G3DSA:3.30.63.10 33 84 1.2E-24 T 09-03-2017 L21SP3_RS08700 3b8d6f59d9944d5fa330cbf5a9af9f45 184 SMART SM00072 4 184 6.3E-51 T 09-03-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit L21SP3_RS08700 3b8d6f59d9944d5fa330cbf5a9af9f45 184 Gene3D G3DSA:3.40.50.300 3 27 2.0E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08700 3b8d6f59d9944d5fa330cbf5a9af9f45 184 Gene3D G3DSA:3.40.50.300 85 183 2.0E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08700 3b8d6f59d9944d5fa330cbf5a9af9f45 184 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 182 1.1E-66 T 09-03-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 L21SP3_RS00390 bf2e678b331495941ed4b809652bff13 766 SUPERFAMILY SSF49899 474 711 1.76E-28 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00390 bf2e678b331495941ed4b809652bff13 766 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 544 708 5.8E-23 T 09-03-2017 L21SP3_RS00390 bf2e678b331495941ed4b809652bff13 766 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 90 257 2.6E-12 T 09-03-2017 L21SP3_RS00390 bf2e678b331495941ed4b809652bff13 766 SUPERFAMILY SSF48726 391 471 8.27E-7 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS00390 bf2e678b331495941ed4b809652bff13 766 Gene3D G3DSA:2.60.120.200 481 711 5.1E-28 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00390 bf2e678b331495941ed4b809652bff13 766 Gene3D G3DSA:2.60.120.200 16 257 1.2E-13 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00390 bf2e678b331495941ed4b809652bff13 766 SUPERFAMILY SSF49899 19 257 1.58E-13 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00390 bf2e678b331495941ed4b809652bff13 766 Gene3D G3DSA:2.60.40.10 387 468 4.7E-6 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS00390 bf2e678b331495941ed4b809652bff13 766 SMART SM00560 108 256 0.0019 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS08870 e0ef1f96fc4f9cd282dff0b9647d9918 455 Gene3D G3DSA:1.20.1600.10 48 453 1.1E-88 T 09-03-2017 L21SP3_RS08870 e0ef1f96fc4f9cd282dff0b9647d9918 455 Pfam PF02321 Outer membrane efflux protein 58 242 1.0E-23 T 09-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP3_RS08870 e0ef1f96fc4f9cd282dff0b9647d9918 455 Pfam PF02321 Outer membrane efflux protein 269 447 1.4E-17 T 09-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP3_RS08870 e0ef1f96fc4f9cd282dff0b9647d9918 455 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 10 450 1.8E-80 T 09-03-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 L21SP3_RS08870 e0ef1f96fc4f9cd282dff0b9647d9918 455 SUPERFAMILY SSF56954 1 452 1.22E-88 T 09-03-2017 L21SP3_RS07160 20ef1b636cbed50cf0d5481bd8d21a43 202 Pfam PF08281 Sigma-70, region 4 138 187 1.1E-14 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS07160 20ef1b636cbed50cf0d5481bd8d21a43 202 Gene3D G3DSA:1.10.1740.10 4 114 2.0E-33 T 09-03-2017 L21SP3_RS07160 20ef1b636cbed50cf0d5481bd8d21a43 202 SUPERFAMILY SSF88946 6 107 6.75E-29 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS07160 20ef1b636cbed50cf0d5481bd8d21a43 202 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 191 2.0E-31 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS07160 20ef1b636cbed50cf0d5481bd8d21a43 202 Gene3D G3DSA:1.10.10.10 132 195 5.0E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS07160 20ef1b636cbed50cf0d5481bd8d21a43 202 SUPERFAMILY SSF88659 130 193 8.72E-15 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS07160 20ef1b636cbed50cf0d5481bd8d21a43 202 Pfam PF04542 Sigma-70 region 2 29 95 8.3E-18 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS11785 eafd4ac58f8fb1c6adc5de0c5318ff11 147 Gene3D G3DSA:3.50.80.10 1 145 1.2E-48 T 09-03-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain L21SP3_RS11785 eafd4ac58f8fb1c6adc5de0c5318ff11 147 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 7.5E-41 T 09-03-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 L21SP3_RS11785 eafd4ac58f8fb1c6adc5de0c5318ff11 147 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 1.5E-44 T 09-03-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 L21SP3_RS11785 eafd4ac58f8fb1c6adc5de0c5318ff11 147 SUPERFAMILY SSF69500 1 145 3.4E-46 T 09-03-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain L21SP3_RS11785 eafd4ac58f8fb1c6adc5de0c5318ff11 147 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 29.263 T 09-03-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 L21SP3_RS04920 da2b009d9e4e43ce58a97fc6eb84e900 277 SUPERFAMILY SSF53335 12 276 5.19E-57 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS04920 da2b009d9e4e43ce58a97fc6eb84e900 277 Pfam PF08241 Methyltransferase domain 70 168 7.3E-23 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 L21SP3_RS04920 da2b009d9e4e43ce58a97fc6eb84e900 277 Gene3D G3DSA:3.40.50.150 21 276 3.9E-62 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS11000 217d27f7259807278cfaca95810a3235 223 Gene3D G3DSA:3.20.20.70 9 220 2.5E-84 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS11000 217d27f7259807278cfaca95810a3235 223 Pfam PF00834 Ribulose-phosphate 3 epimerase family 10 204 3.7E-69 T 09-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 L21SP3_RS11000 217d27f7259807278cfaca95810a3235 223 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 38 52 - T 09-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 L21SP3_RS11000 217d27f7259807278cfaca95810a3235 223 PIRSF PIRSF001461 6 223 1.2E-80 T 09-03-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 L21SP3_RS11000 217d27f7259807278cfaca95810a3235 223 SUPERFAMILY SSF51366 9 218 3.87E-64 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP3_RS11000 217d27f7259807278cfaca95810a3235 223 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 11 216 1.6E-75 T 09-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 L21SP3_RS11000 217d27f7259807278cfaca95810a3235 223 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 140 162 - T 09-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 L21SP3_RS10330 b9a44048afa3de6a28ea4f126978a0c4 250 Gene3D G3DSA:2.40.50.140 3 85 6.0E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS10330 b9a44048afa3de6a28ea4f126978a0c4 250 Hamap MF_00201 DNA repair protein RecO [recO]. 1 246 19.383 T 09-03-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 L21SP3_RS10330 b9a44048afa3de6a28ea4f126978a0c4 250 Pfam PF02565 Recombination protein O C terminal 97 235 1.7E-11 T 09-03-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 L21SP3_RS10330 b9a44048afa3de6a28ea4f126978a0c4 250 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 238 7.0E-30 T 09-03-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 L21SP3_RS10330 b9a44048afa3de6a28ea4f126978a0c4 250 Pfam PF11967 Recombination protein O N terminal 1 80 2.8E-14 T 09-03-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal L21SP3_RS10330 b9a44048afa3de6a28ea4f126978a0c4 250 SUPERFAMILY SSF57863 84 205 5.23E-13 T 09-03-2017 L21SP3_RS10330 b9a44048afa3de6a28ea4f126978a0c4 250 SUPERFAMILY SSF50249 2 80 3.26E-11 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS08085 31d735aa61aeb9544b803941af92cd54 297 Gene3D G3DSA:3.30.470.20 118 248 5.5E-54 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP3_RS08085 31d735aa61aeb9544b803941af92cd54 297 ProSitePatterns PS01057 SAICAR synthetase signature 1. 106 120 - T 09-03-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 L21SP3_RS08085 31d735aa61aeb9544b803941af92cd54 297 SUPERFAMILY SSF56104 13 295 6.54E-105 T 09-03-2017 L21SP3_RS08085 31d735aa61aeb9544b803941af92cd54 297 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 16 294 8.0E-75 T 09-03-2017 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 L21SP3_RS08085 31d735aa61aeb9544b803941af92cd54 297 Pfam PF01259 SAICAR synthetase 14 260 1.3E-101 T 09-03-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 L21SP3_RS08085 31d735aa61aeb9544b803941af92cd54 297 Gene3D G3DSA:3.30.200.20 13 117 1.6E-42 T 09-03-2017 L21SP3_RS08085 31d735aa61aeb9544b803941af92cd54 297 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 12 292 26.847 T 09-03-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 L21SP3_RS06570 b8c12b0c564e6366da1a314bc8cc98fa 95 PRINTS PR00107 Phosphocarrier protein signature 13 29 6.1E-15 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like L21SP3_RS06570 b8c12b0c564e6366da1a314bc8cc98fa 95 PRINTS PR00107 Phosphocarrier protein signature 53 70 6.1E-15 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like L21SP3_RS06570 b8c12b0c564e6366da1a314bc8cc98fa 95 PRINTS PR00107 Phosphocarrier protein signature 38 53 6.1E-15 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like L21SP3_RS06570 b8c12b0c564e6366da1a314bc8cc98fa 95 Pfam PF00381 PTS HPr component phosphorylation site 4 82 4.3E-26 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like L21SP3_RS06570 b8c12b0c564e6366da1a314bc8cc98fa 95 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 7.8E-26 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like L21SP3_RS06570 b8c12b0c564e6366da1a314bc8cc98fa 95 Gene3D G3DSA:3.30.1340.10 1 86 9.8E-30 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like L21SP3_RS06570 b8c12b0c564e6366da1a314bc8cc98fa 95 SUPERFAMILY SSF55594 4 84 9.68E-24 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 Gene3D G3DSA:2.115.10.20 663 836 9.4E-8 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 SMART SM00640 639 1053 7.3E-76 T 09-03-2017 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 Gene3D G3DSA:2.60.120.200 428 610 1.2E-29 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 Gene3D G3DSA:2.60.120.200 384 396 1.2E-29 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 Gene3D G3DSA:2.60.120.200 23 255 2.0E-14 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 639 930 1.4E-58 T 09-03-2017 IPR013148 Glycosyl hydrolase family 32, N-terminal L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 443 606 4.5E-25 T 09-03-2017 L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 102 254 5.0E-11 T 09-03-2017 L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 SUPERFAMILY SSF49899 97 260 5.87E-16 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 Gene3D G3DSA:2.60.120.560 905 1088 1.4E-34 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 979 1053 1.8E-13 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 SUPERFAMILY SSF75005 630 930 5.97E-67 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 SMART SM00560 461 603 1.7E-12 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 SUPERFAMILY SSF49899 930 1093 6.33E-27 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05455 7811ff5ed2380c5fe14a08cb6cff7d45 1097 SUPERFAMILY SSF49899 428 611 1.48E-29 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05525 b8bb715facb52446d811a90b064cb961 269 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 93 215 1.0E-21 T 09-03-2017 IPR006342 Methyltransferase FkbM L21SP3_RS05525 b8bb715facb52446d811a90b064cb961 269 Pfam PF05050 Methyltransferase FkbM domain 96 217 4.9E-12 T 09-03-2017 IPR006342 Methyltransferase FkbM L21SP3_RS05525 b8bb715facb52446d811a90b064cb961 269 Gene3D G3DSA:3.40.50.150 80 254 8.6E-26 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS05525 b8bb715facb52446d811a90b064cb961 269 SUPERFAMILY SSF53335 50 255 2.97E-34 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS06555 05b20dbe1d7c567238f4e7cf825d356a 505 SUPERFAMILY SSF50249 41 134 2.21E-17 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS06555 05b20dbe1d7c567238f4e7cf825d356a 505 Gene3D G3DSA:2.40.50.140 31 135 5.0E-32 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS06555 05b20dbe1d7c567238f4e7cf825d356a 505 Pfam PF00575 S1 RNA binding domain 39 124 1.4E-7 T 09-03-2017 IPR003029 S1 domain GO:0003676 L21SP3_RS06555 05b20dbe1d7c567238f4e7cf825d356a 505 SMART SM00316 38 129 7.7E-8 T 09-03-2017 IPR022967 RNA-binding domain, S1 L21SP3_RS06555 05b20dbe1d7c567238f4e7cf825d356a 505 Pfam PF10150 Ribonuclease E/G family 131 401 4.2E-96 T 09-03-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 L21SP3_RS06555 05b20dbe1d7c567238f4e7cf825d356a 505 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 14 434 3.0E-151 T 09-03-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 L21SP3_RS07870 281812c6e2274304f223433b862a4761 505 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 104 488 9.3E-61 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 L21SP3_RS07870 281812c6e2274304f223433b862a4761 505 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 402 416 1.1E-22 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 L21SP3_RS07870 281812c6e2274304f223433b862a4761 505 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 466 479 1.1E-22 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 L21SP3_RS07870 281812c6e2274304f223433b862a4761 505 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 329 351 1.1E-22 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 L21SP3_RS07870 281812c6e2274304f223433b862a4761 505 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 387 401 1.1E-22 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 L21SP3_RS07870 281812c6e2274304f223433b862a4761 505 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 116 135 1.1E-22 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 L21SP3_RS07870 281812c6e2274304f223433b862a4761 505 SUPERFAMILY SSF56601 75 499 1.84E-62 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like L21SP3_RS07870 281812c6e2274304f223433b862a4761 505 Gene3D G3DSA:3.40.710.10 283 504 1.2E-47 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like L21SP3_RS07870 281812c6e2274304f223433b862a4761 505 Gene3D G3DSA:3.40.710.10 83 136 2.2E-5 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like L21SP3_RS07870 281812c6e2274304f223433b862a4761 505 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 77 498 2.7E-75 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 Gene3D G3DSA:3.40.50.300 40 279 1.0E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 SUPERFAMILY SSF52540 20 279 5.67E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 Hamap MF_00268 Protein RecA [recA]. 16 341 48.027 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 Pfam PF00154 recA bacterial DNA recombination protein 20 280 7.0E-130 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 ProSitePatterns PS00321 recA signature. 224 232 - T 09-03-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 19 334 2.3E-155 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 PRINTS PR00142 RecA protein signature 176 205 2.4E-83 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 PRINTS PR00142 RecA protein signature 255 284 2.4E-83 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 PRINTS PR00142 RecA protein signature 104 133 2.4E-83 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 PRINTS PR00142 RecA protein signature 138 167 2.4E-83 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 PRINTS PR00142 RecA protein signature 309 326 2.4E-83 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 PRINTS PR00142 RecA protein signature 221 249 2.4E-83 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 SUPERFAMILY SSF54752 282 336 1.96E-17 T 09-03-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 SMART SM00382 68 239 1.1E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS07080 41f5647ee8285d5bfee93bf812310c45 357 Gene3D G3DSA:3.30.250.10 282 336 7.7E-22 T 09-03-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal L21SP3_RS08980 897d686d07e09cb5537ea8dda956e328 134 Pfam PF07589 PEP-CTERM motif 113 132 1.5E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS08980 897d686d07e09cb5537ea8dda956e328 134 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 113 132 4.4E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS04905 d24dca7b2870b2b5a5ff0872fea2c27f 274 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 09-03-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS04905 d24dca7b2870b2b5a5ff0872fea2c27f 274 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 09-03-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS04905 d24dca7b2870b2b5a5ff0872fea2c27f 274 Gene3D G3DSA:1.10.8.10 2 55 2.8E-22 T 09-03-2017 L21SP3_RS04905 d24dca7b2870b2b5a5ff0872fea2c27f 274 SUPERFAMILY SSF54713 57 140 3.79E-16 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS04905 d24dca7b2870b2b5a5ff0872fea2c27f 274 SUPERFAMILY SSF54713 149 274 3.14E-35 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS04905 d24dca7b2870b2b5a5ff0872fea2c27f 274 SUPERFAMILY SSF46934 3 55 5.05E-16 T 09-03-2017 IPR009060 UBA-like GO:0005515 L21SP3_RS04905 d24dca7b2870b2b5a5ff0872fea2c27f 274 Gene3D G3DSA:3.30.479.20 238 274 1.9E-20 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS04905 d24dca7b2870b2b5a5ff0872fea2c27f 274 Gene3D G3DSA:3.30.479.20 149 191 1.9E-20 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS04905 d24dca7b2870b2b5a5ff0872fea2c27f 274 Hamap MF_00050 Elongation factor Ts [tsf]. 1 274 56.125 T 09-03-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS04905 d24dca7b2870b2b5a5ff0872fea2c27f 274 Gene3D G3DSA:3.30.479.20 57 144 3.1E-13 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS04905 d24dca7b2870b2b5a5ff0872fea2c27f 274 Pfam PF00889 Elongation factor TS 72 274 3.5E-57 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS04905 d24dca7b2870b2b5a5ff0872fea2c27f 274 Gene3D G3DSA:1.10.286.20 197 237 1.2E-12 T 09-03-2017 L21SP3_RS04905 d24dca7b2870b2b5a5ff0872fea2c27f 274 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 274 1.6E-73 T 09-03-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 L21SP3_RS08380 cfe2482113cdb732e4a626d4df7fba14 213 Pfam PF07589 PEP-CTERM motif 192 213 3.3E-7 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS08380 cfe2482113cdb732e4a626d4df7fba14 213 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 193 213 1.5E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 Gene3D G3DSA:3.40.50.720 1 166 1.6E-68 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 156 163 - T 09-03-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 SMART SM00846 3 158 1.7E-78 T 09-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 163 319 6.1E-71 T 09-03-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 330 1.1E-132 T 09-03-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 SUPERFAMILY SSF55347 158 320 7.14E-75 T 09-03-2017 L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 152 170 1.3E-36 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 115 128 1.3E-36 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 179 195 1.3E-36 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 275 290 1.3E-36 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 235 252 1.3E-36 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 SUPERFAMILY SSF51735 1 185 8.75E-55 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 Gene3D G3DSA:3.30.360.10 167 321 1.4E-79 T 09-03-2017 L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 PIRSF PIRSF000149 1 340 4.8E-128 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS06665 6d7aed49f3eb3204e3aa211aa4fe82f3 340 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 158 3.0E-52 T 09-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS06635 996664d0bf4508708009245bc2a22be9 280 Pfam PF00175 Oxidoreductase NAD-binding domain 106 198 2.4E-4 T 09-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 L21SP3_RS06635 996664d0bf4508708009245bc2a22be9 280 Gene3D G3DSA:2.10.240.10 216 249 5.7E-5 T 09-03-2017 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain L21SP3_RS06635 996664d0bf4508708009245bc2a22be9 280 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 213 250 6.9E-13 T 09-03-2017 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain L21SP3_RS06635 996664d0bf4508708009245bc2a22be9 280 Gene3D G3DSA:3.40.50.80 96 211 7.3E-37 T 09-03-2017 L21SP3_RS06635 996664d0bf4508708009245bc2a22be9 280 Gene3D G3DSA:2.40.30.10 4 93 1.4E-21 T 09-03-2017 L21SP3_RS06635 996664d0bf4508708009245bc2a22be9 280 PIRSF PIRSF006816 1 256 2.6E-67 T 09-03-2017 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 L21SP3_RS06635 996664d0bf4508708009245bc2a22be9 280 SUPERFAMILY SSF63380 3 94 3.71E-17 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 L21SP3_RS06635 996664d0bf4508708009245bc2a22be9 280 SUPERFAMILY SSF52343 90 249 7.73E-34 T 09-03-2017 L21SP3_RS04665 065d617ff57568166ab54cd5ac4ee009 247 Gene3D G3DSA:2.10.70.20 168 206 9.3E-7 T 09-03-2017 L21SP3_RS04665 065d617ff57568166ab54cd5ac4ee009 247 SUPERFAMILY SSF54523 46 206 1.8E-12 T 09-03-2017 L21SP3_RS04665 065d617ff57568166ab54cd5ac4ee009 247 Pfam PF11612 Type II secretion system (T2SS), protein J 86 207 3.3E-11 T 09-03-2017 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 L21SP3_RS04665 065d617ff57568166ab54cd5ac4ee009 247 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 29 8.8E-4 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS00140 76cd3185f078dea8f7134c9b402622c8 343 SMART SM00327 92 267 1.4E-22 T 09-03-2017 IPR002035 von Willebrand factor, type A L21SP3_RS00140 76cd3185f078dea8f7134c9b402622c8 343 SUPERFAMILY SSF53300 89 247 8.46E-30 T 09-03-2017 IPR002035 von Willebrand factor, type A L21SP3_RS00140 76cd3185f078dea8f7134c9b402622c8 343 Pfam PF13519 von Willebrand factor type A domain 95 203 1.3E-24 T 09-03-2017 IPR002035 von Willebrand factor, type A L21SP3_RS00140 76cd3185f078dea8f7134c9b402622c8 343 Gene3D G3DSA:3.40.50.410 89 263 1.4E-23 T 09-03-2017 IPR002035 von Willebrand factor, type A L21SP3_RS08560 18ae4b2b2f34e56875ee313861c4ba0b 358 Pfam PF13565 Homeodomain-like domain 82 151 1.1E-10 T 09-03-2017 L21SP3_RS08560 18ae4b2b2f34e56875ee313861c4ba0b 358 SUPERFAMILY SSF53098 174 327 2.12E-17 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS08560 18ae4b2b2f34e56875ee313861c4ba0b 358 SUPERFAMILY SSF46689 77 155 1.18E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS08560 18ae4b2b2f34e56875ee313861c4ba0b 358 Gene3D G3DSA:3.30.420.10 175 327 7.3E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS08560 18ae4b2b2f34e56875ee313861c4ba0b 358 Pfam PF13683 Integrase core domain 266 328 2.0E-11 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS11090 7f7ec5bf923eed0eac2bbd7907aa83df 795 Pfam PF11790 Glycosyl hydrolase catalytic core 320 542 1.7E-37 T 09-03-2017 IPR024655 Uncharacterised protein family, glycosyl hydrolase catalytic domain L21SP3_RS11090 7f7ec5bf923eed0eac2bbd7907aa83df 795 SUPERFAMILY SSF51445 358 543 1.21E-13 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS11090 7f7ec5bf923eed0eac2bbd7907aa83df 795 Gene3D G3DSA:1.10.1330.10 743 791 6.7E-5 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS11090 7f7ec5bf923eed0eac2bbd7907aa83df 795 Gene3D G3DSA:3.20.20.80 414 498 2.2E-9 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 6 343 59.451 T 09-03-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 8 327 1.2E-125 T 09-03-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 ProSitePatterns PS01016 Glycoprotease family signature. 101 121 - T 09-03-2017 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 9 22 2.8E-43 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 81 101 2.8E-43 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 136 148 2.8E-43 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 102 121 2.8E-43 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 277 286 2.8E-43 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 159 180 2.8E-43 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 SUPERFAMILY SSF53067 7 126 9.06E-29 T 09-03-2017 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 Pfam PF00814 Glycoprotease family 28 320 2.4E-96 T 09-03-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 SUPERFAMILY SSF53067 106 326 2.56E-38 T 09-03-2017 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 Gene3D G3DSA:3.30.420.40 7 164 1.2E-41 T 09-03-2017 L21SP3_RS05220 a7cc580c3886aa6705289f1314d47d52 343 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 9 320 4.4E-107 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 L21SP3_RS03840 d518d39020ee619f46a42cdf5cea61af 497 SMART SM01118 2 172 5.1E-5 T 09-03-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 L21SP3_RS03840 d518d39020ee619f46a42cdf5cea61af 497 Gene3D G3DSA:3.40.50.10330 217 319 3.3E-5 T 09-03-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 L21SP3_RS03840 d518d39020ee619f46a42cdf5cea61af 497 Pfam PF01928 CYTH domain 3 146 4.0E-16 T 09-03-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 L21SP3_RS03840 d518d39020ee619f46a42cdf5cea61af 497 SUPERFAMILY SSF111331 207 496 8.24E-58 T 09-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain L21SP3_RS03840 d518d39020ee619f46a42cdf5cea61af 497 Gene3D G3DSA:2.40.320.10 4 168 2.9E-29 T 09-03-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 L21SP3_RS03840 d518d39020ee619f46a42cdf5cea61af 497 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 4 155 3.3E-18 T 09-03-2017 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 L21SP3_RS03840 d518d39020ee619f46a42cdf5cea61af 497 Pfam PF00781 Diacylglycerol kinase catalytic domain 208 330 2.4E-17 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 L21SP3_RS03840 d518d39020ee619f46a42cdf5cea61af 497 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 5 144 3.0E-9 T 09-03-2017 L21SP3_RS03840 d518d39020ee619f46a42cdf5cea61af 497 SUPERFAMILY SSF55154 4 158 1.96E-26 T 09-03-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 L21SP3_RS03280 b9e38076ce10f18ab3002503e6e660ad 171 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 16 157 44.762 T 09-03-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 L21SP3_RS03280 b9e38076ce10f18ab3002503e6e660ad 171 Pfam PF14437 MafB19-like deaminase 12 157 4.3E-36 T 09-03-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 L21SP3_RS03280 b9e38076ce10f18ab3002503e6e660ad 171 SUPERFAMILY SSF53927 8 158 1.14E-54 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 L21SP3_RS03280 b9e38076ce10f18ab3002503e6e660ad 171 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 61 98 - T 09-03-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 L21SP3_RS03280 b9e38076ce10f18ab3002503e6e660ad 171 Gene3D G3DSA:3.40.140.10 4 155 2.0E-57 T 09-03-2017 L21SP3_RS09605 4dca5fce36141b4d0cbd128abd5b106f 277 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 277 28.923 T 09-03-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 L21SP3_RS09605 4dca5fce36141b4d0cbd128abd5b106f 277 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 276 3.9E-79 T 09-03-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 L21SP3_RS09605 4dca5fce36141b4d0cbd128abd5b106f 277 Pfam PF02401 LytB protein 3 274 1.9E-82 T 09-03-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 Gene3D G3DSA:2.120.10.90 528 834 1.6E-127 T 09-03-2017 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 Gene3D G3DSA:1.10.268.10 368 493 3.3E-36 T 09-03-2017 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 38 503 1.2E-147 T 09-03-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 Gene3D G3DSA:3.30.1360.40 242 338 9.6E-33 T 09-03-2017 IPR024946 Arginine repressor C-terminal-like domain L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 SUPERFAMILY SSF101904 530 846 7.06E-108 T 09-03-2017 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 Gene3D G3DSA:3.90.199.10 40 222 2.4E-75 T 09-03-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 SUPERFAMILY SSF56719 36 518 2.62E-164 T 09-03-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 SMART SM00434 17 496 5.1E-240 T 09-03-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 11 837 23.305 T 09-03-2017 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 788 832 9.3E-14 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 585 619 1.5E-8 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 640 684 1.3E-8 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 537 581 9.0E-11 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 687 733 3.5E-16 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 739 784 5.7E-11 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 L21SP3_RS05230 10fae2231b999fecbcc629cdaa3c7325 856 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 16 834 0.0 T 09-03-2017 L21SP3_RS03310 bb5182f2c29624159f5b488f19ecb47a 368 SUPERFAMILY SSF53067 10 286 6.76E-32 T 09-03-2017 L21SP3_RS03310 bb5182f2c29624159f5b488f19ecb47a 368 Pfam PF00480 ROK family 11 300 8.5E-28 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 L21SP3_RS03310 bb5182f2c29624159f5b488f19ecb47a 368 Gene3D G3DSA:3.30.420.40 6 158 6.6E-29 T 09-03-2017 L21SP3_RS03310 bb5182f2c29624159f5b488f19ecb47a 368 Gene3D G3DSA:3.30.420.40 159 285 8.9E-21 T 09-03-2017 L21SP3_RS10730 bb5182f2c29624159f5b488f19ecb47a 368 SUPERFAMILY SSF53067 10 286 6.76E-32 T 09-03-2017 L21SP3_RS10730 bb5182f2c29624159f5b488f19ecb47a 368 Pfam PF00480 ROK family 11 300 8.5E-28 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 L21SP3_RS10730 bb5182f2c29624159f5b488f19ecb47a 368 Gene3D G3DSA:3.30.420.40 6 158 6.6E-29 T 09-03-2017 L21SP3_RS10730 bb5182f2c29624159f5b488f19ecb47a 368 Gene3D G3DSA:3.30.420.40 159 285 8.9E-21 T 09-03-2017 L21SP3_RS08605 dfe08194b403b52360d1b87e1f0fcb29 603 SUPERFAMILY SSF56519 51 242 1.31E-26 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 L21SP3_RS08605 dfe08194b403b52360d1b87e1f0fcb29 603 Gene3D G3DSA:3.90.1310.10 154 249 7.7E-20 T 09-03-2017 L21SP3_RS08605 dfe08194b403b52360d1b87e1f0fcb29 603 SUPERFAMILY SSF56601 195 598 4.38E-86 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like L21SP3_RS08605 dfe08194b403b52360d1b87e1f0fcb29 603 Gene3D G3DSA:3.40.710.10 250 593 1.8E-82 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like L21SP3_RS08605 dfe08194b403b52360d1b87e1f0fcb29 603 Pfam PF00905 Penicillin binding protein transpeptidase domain 268 586 3.7E-60 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 L21SP3_RS08605 dfe08194b403b52360d1b87e1f0fcb29 603 Pfam PF03717 Penicillin-binding Protein dimerisation domain 53 226 2.8E-14 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 L21SP3_RS09270 d46166feb1a6866843f5878cb98d959e 587 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 196 404 8.1E-12 T 09-03-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 L21SP3_RS09270 d46166feb1a6866843f5878cb98d959e 587 Pfam PF11412 Disulphide bond corrector protein DsbC 40 147 2.1E-6 T 09-03-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain L21SP3_RS09270 d46166feb1a6866843f5878cb98d959e 587 Pfam PF13899 Thioredoxin-like 469 558 7.0E-9 T 09-03-2017 L21SP3_RS09270 d46166feb1a6866843f5878cb98d959e 587 SUPERFAMILY SSF52833 468 583 2.92E-13 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS09270 d46166feb1a6866843f5878cb98d959e 587 Gene3D G3DSA:2.60.40.1250 77 147 1.3E-4 T 09-03-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain L21SP3_RS09270 d46166feb1a6866843f5878cb98d959e 587 Gene3D G3DSA:3.40.30.10 468 583 1.3E-19 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS10270 1f058960cb915c9f61ae7aadca9a8ed4 303 Pfam PF04909 Amidohydrolase 46 247 8.9E-15 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 L21SP3_RS10270 1f058960cb915c9f61ae7aadca9a8ed4 303 SUPERFAMILY SSF51556 45 260 5.38E-24 T 09-03-2017 IPR032466 Metal-dependent hydrolase L21SP3_RS10270 1f058960cb915c9f61ae7aadca9a8ed4 303 Gene3D G3DSA:3.20.20.140 23 256 4.6E-25 T 09-03-2017 L21SP3_RS04115 36d2b23edb9aaca244261f098dfcc682 540 Pfam PF01609 Transposase DDE domain 200 470 2.2E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS04115 36d2b23edb9aaca244261f098dfcc682 540 SUPERFAMILY SSF53098 160 516 2.43E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS08890 36d2b23edb9aaca244261f098dfcc682 540 Pfam PF01609 Transposase DDE domain 200 470 2.2E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS08890 36d2b23edb9aaca244261f098dfcc682 540 SUPERFAMILY SSF53098 160 516 2.43E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS07740 5373757bbaddd35c8be771ca8aa01196 685 SUPERFAMILY SSF50249 3 175 3.26E-33 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS07740 5373757bbaddd35c8be771ca8aa01196 685 Gene3D G3DSA:3.40.50.300 247 442 3.0E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07740 5373757bbaddd35c8be771ca8aa01196 685 SMART SM00487 259 448 6.8E-33 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain L21SP3_RS07740 5373757bbaddd35c8be771ca8aa01196 685 Gene3D G3DSA:2.40.50.140 50 137 2.7E-21 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS07740 5373757bbaddd35c8be771ca8aa01196 685 Gene3D G3DSA:3.40.50.300 443 625 6.6E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07740 5373757bbaddd35c8be771ca8aa01196 685 SMART SM00490 491 579 1.8E-22 T 09-03-2017 IPR001650 Helicase, C-terminal L21SP3_RS07740 5373757bbaddd35c8be771ca8aa01196 685 Pfam PF17191 RecG wedge domain 8 171 5.5E-20 T 09-03-2017 IPR033454 RecG, wedge domain L21SP3_RS07740 5373757bbaddd35c8be771ca8aa01196 685 SUPERFAMILY SSF52540 179 442 5.69E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07740 5373757bbaddd35c8be771ca8aa01196 685 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 27 654 2.5E-211 T 09-03-2017 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 L21SP3_RS07740 5373757bbaddd35c8be771ca8aa01196 685 SUPERFAMILY SSF52540 451 643 3.17E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07740 5373757bbaddd35c8be771ca8aa01196 685 Pfam PF00270 DEAD/DEAH box helicase 264 422 4.0E-18 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 L21SP3_RS07740 5373757bbaddd35c8be771ca8aa01196 685 Pfam PF00271 Helicase conserved C-terminal domain 464 578 1.8E-20 T 09-03-2017 IPR001650 Helicase, C-terminal L21SP3_RS03130 2457c7c1507ab81f5fc2955f03994406 679 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 525 619 1.3E-10 T 09-03-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 L21SP3_RS03130 2457c7c1507ab81f5fc2955f03994406 679 Gene3D G3DSA:2.60.40.10 38 124 4.6E-20 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS03130 2457c7c1507ab81f5fc2955f03994406 679 Gene3D G3DSA:2.60.40.1180 523 619 4.4E-17 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta L21SP3_RS03130 2457c7c1507ab81f5fc2955f03994406 679 Pfam PF00128 Alpha amylase, catalytic domain 278 476 3.8E-12 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP3_RS03130 2457c7c1507ab81f5fc2955f03994406 679 Pfam PF00128 Alpha amylase, catalytic domain 167 239 9.9E-12 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP3_RS03130 2457c7c1507ab81f5fc2955f03994406 679 SUPERFAMILY SSF51445 125 506 2.91E-90 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS03130 2457c7c1507ab81f5fc2955f03994406 679 SUPERFAMILY SSF51011 521 618 1.8E-14 T 09-03-2017 L21SP3_RS03130 2457c7c1507ab81f5fc2955f03994406 679 Gene3D G3DSA:3.20.20.80 130 506 2.0E-81 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS03130 2457c7c1507ab81f5fc2955f03994406 679 SUPERFAMILY SSF81296 44 131 7.35E-19 T 09-03-2017 IPR014756 Immunoglobulin E-set L21SP3_RS03130 2457c7c1507ab81f5fc2955f03994406 679 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 38 102 2.4E-13 T 09-03-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 L21SP3_RS03130 2457c7c1507ab81f5fc2955f03994406 679 SUPERFAMILY SSF63446 627 676 5.36E-5 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS03130 2457c7c1507ab81f5fc2955f03994406 679 SMART SM00642 144 504 1.2E-9 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 L21SP3_RS03130 2457c7c1507ab81f5fc2955f03994406 679 PIRSF PIRSF000463 30 629 2.6E-89 T 09-03-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 L21SP3_RS08565 1f3ac6f80d61295feaaa0e5538e9c651 188 SMART SM00857 19 171 9.1E-30 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 L21SP3_RS08565 1f3ac6f80d61295feaaa0e5538e9c651 188 SUPERFAMILY SSF53041 19 170 3.01E-24 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 L21SP3_RS08565 1f3ac6f80d61295feaaa0e5538e9c651 188 Pfam PF00239 Resolvase, N terminal domain 19 170 3.0E-23 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 L21SP3_RS08565 1f3ac6f80d61295feaaa0e5538e9c651 188 Gene3D G3DSA:3.40.50.1390 19 152 6.8E-15 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 L21SP3_RS02350 9c0e355e0ec7acf3486493bf472d4fd9 224 Pfam PF13189 Cytidylate kinase-like family 26 185 3.4E-22 T 09-03-2017 IPR026865 Cytidylate kinase-like family MetaCyc: PWY-7205 L21SP3_RS02350 9c0e355e0ec7acf3486493bf472d4fd9 224 Gene3D G3DSA:3.40.50.300 22 217 5.4E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11195 6165d21ec9d729d77f86ee0431dda921 107 SUPERFAMILY SSF81301 6 94 7.25E-14 T 09-03-2017 L21SP3_RS11195 6165d21ec9d729d77f86ee0431dda921 107 Pfam PF01909 Nucleotidyltransferase domain 10 56 1.3E-8 T 09-03-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 L21SP3_RS11195 6165d21ec9d729d77f86ee0431dda921 107 Gene3D G3DSA:3.30.460.10 4 100 7.2E-15 T 09-03-2017 L21SP3_RS04210 cba5d969df16b310df1fb2ba407ad986 400 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 11 390 44.061 T 09-03-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 L21SP3_RS04210 cba5d969df16b310df1fb2ba407ad986 400 SUPERFAMILY SSF53383 15 391 7.07E-129 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS04210 cba5d969df16b310df1fb2ba407ad986 400 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 13 387 3.6E-146 T 09-03-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 L21SP3_RS04210 cba5d969df16b310df1fb2ba407ad986 400 Gene3D G3DSA:3.40.640.10 57 284 1.5E-88 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS04210 cba5d969df16b310df1fb2ba407ad986 400 Gene3D G3DSA:3.90.1150.10 285 390 2.5E-38 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS04210 cba5d969df16b310df1fb2ba407ad986 400 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216 253 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 L21SP3_RS04210 cba5d969df16b310df1fb2ba407ad986 400 Pfam PF00202 Aminotransferase class-III 21 387 2.5E-120 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 L21SP3_RS06120 2e12f5354a3797e6e7a95acf9914f28f 149 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 145 2.3E-34 T 09-03-2017 IPR021131 Ribosomal protein L18e/L15P L21SP3_RS06120 2e12f5354a3797e6e7a95acf9914f28f 149 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 148 20.046 T 09-03-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 L21SP3_RS06120 2e12f5354a3797e6e7a95acf9914f28f 149 SUPERFAMILY SSF52080 4 147 2.88E-40 T 09-03-2017 IPR021131 Ribosomal protein L18e/L15P L21SP3_RS06120 2e12f5354a3797e6e7a95acf9914f28f 149 ProSitePatterns PS00475 Ribosomal protein L15 signature. 112 142 - T 09-03-2017 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06120 2e12f5354a3797e6e7a95acf9914f28f 149 Gene3D G3DSA:3.100.10.10 32 148 2.6E-34 T 09-03-2017 L21SP3_RS06120 2e12f5354a3797e6e7a95acf9914f28f 149 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 4 144 3.1E-48 T 09-03-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS01125 26779567b090b8a47aab6f66323a071e 115 Gene3D G3DSA:1.20.120.580 69 109 2.5E-6 T 09-03-2017 L21SP3_RS01125 26779567b090b8a47aab6f66323a071e 115 Pfam PF01934 Protein of unknown function DUF86 13 103 4.1E-22 T 09-03-2017 IPR008201 Protein of unknown function DUF86 L21SP3_RS07845 bd45bd162ea05766e4f6bc07069eb9be 437 SUPERFAMILY SSF102114 119 358 9.55E-33 T 09-03-2017 L21SP3_RS07845 bd45bd162ea05766e4f6bc07069eb9be 437 Pfam PF13353 4Fe-4S single cluster domain 130 241 3.6E-5 T 09-03-2017 L21SP3_RS07845 bd45bd162ea05766e4f6bc07069eb9be 437 Pfam PF12544 Lysine-2,3-aminomutase 321 437 2.1E-44 T 09-03-2017 IPR025895 Lysine-2,3-aminomutase, C-terminal domain L21SP3_RS07845 bd45bd162ea05766e4f6bc07069eb9be 437 PIRSF PIRSF004911 2 401 8.1E-152 T 09-03-2017 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase L21SP3_RS07845 bd45bd162ea05766e4f6bc07069eb9be 437 Gene3D G3DSA:3.20.20.70 114 348 7.4E-20 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS07845 bd45bd162ea05766e4f6bc07069eb9be 437 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 18 433 1.6E-233 T 09-03-2017 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 L21SP3_RS07845 bd45bd162ea05766e4f6bc07069eb9be 437 Pfam PF04055 Radical SAM superfamily 130 277 2.6E-12 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS07845 bd45bd162ea05766e4f6bc07069eb9be 437 TIGRFAM TIGR00238 TIGR00238: KamA family protein 21 342 1.5E-106 T 09-03-2017 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase L21SP3_RS10860 c909b1d4466b8ddce77b13a920163e6e 453 ProSitePatterns PS00216 Sugar transport proteins signature 1. 311 328 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP3_RS10860 c909b1d4466b8ddce77b13a920163e6e 453 Pfam PF00083 Sugar (and other) transporter 10 448 1.4E-101 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 L21SP3_RS10860 c909b1d4466b8ddce77b13a920163e6e 453 ProSitePatterns PS00216 Sugar transport proteins signature 1. 63 80 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP3_RS10860 c909b1d4466b8ddce77b13a920163e6e 453 Gene3D G3DSA:1.20.1250.20 256 448 7.4E-21 T 09-03-2017 L21SP3_RS10860 c909b1d4466b8ddce77b13a920163e6e 453 Gene3D G3DSA:1.20.1250.20 13 192 8.6E-24 T 09-03-2017 L21SP3_RS10860 c909b1d4466b8ddce77b13a920163e6e 453 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 6 446 4.3E-103 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS10860 c909b1d4466b8ddce77b13a920163e6e 453 SUPERFAMILY SSF103473 4 448 4.19E-67 T 09-03-2017 IPR020846 Major facilitator superfamily domain L21SP3_RS10860 c909b1d4466b8ddce77b13a920163e6e 453 ProSitePatterns PS00217 Sugar transport proteins signature 2. 105 130 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP3_RS10860 c909b1d4466b8ddce77b13a920163e6e 453 PRINTS PR00171 Sugar transporter signature 267 277 1.2E-21 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS10860 c909b1d4466b8ddce77b13a920163e6e 453 PRINTS PR00171 Sugar transporter signature 351 372 1.2E-21 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS10860 c909b1d4466b8ddce77b13a920163e6e 453 PRINTS PR00171 Sugar transporter signature 374 386 1.2E-21 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS10860 c909b1d4466b8ddce77b13a920163e6e 453 PRINTS PR00171 Sugar transporter signature 17 27 1.2E-21 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS10860 c909b1d4466b8ddce77b13a920163e6e 453 PRINTS PR00171 Sugar transporter signature 100 119 1.2E-21 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS07430 d8c8355d24506413b1cf09db89f15c88 415 Pfam PF00999 Sodium/hydrogen exchanger family 8 388 3.8E-37 T 09-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 L21SP3_RS04135 43062f8816b3e2325feadfea68580caf 118 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 117 5.0E-37 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 L21SP3_RS04135 43062f8816b3e2325feadfea68580caf 118 SUPERFAMILY SSF50692 1 117 5.34E-39 T 09-03-2017 IPR009010 Aspartate decarboxylase-like domain L21SP3_RS04135 43062f8816b3e2325feadfea68580caf 118 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 6 116 3.0E-26 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 L21SP3_RS04135 43062f8816b3e2325feadfea68580caf 118 PIRSF PIRSF006246 1 118 3.2E-42 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 L21SP3_RS04135 43062f8816b3e2325feadfea68580caf 118 Gene3D G3DSA:2.40.40.20 1 117 1.9E-44 T 09-03-2017 L21SP3_RS04135 43062f8816b3e2325feadfea68580caf 118 Pfam PF02261 Aspartate decarboxylase 1 114 1.1E-42 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 L21SP3_RS04135 43062f8816b3e2325feadfea68580caf 118 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 118 55.627 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 L21SP3_RS09570 adb77b986d75f37db8e87c710209383e 332 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 11 299 1.8E-21 T 09-03-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD L21SP3_RS09570 adb77b986d75f37db8e87c710209383e 332 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 8 307 5.3E-45 T 09-03-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD L21SP3_RS04425 ed3816f301bfa79195ba2652655e0cfc 260 SUPERFAMILY SSF81336 83 253 1.7E-36 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 L21SP3_RS04425 ed3816f301bfa79195ba2652655e0cfc 260 PRINTS PR00123 ATP synthase A subunit signature 164 179 3.4E-24 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 L21SP3_RS04425 ed3816f301bfa79195ba2652655e0cfc 260 PRINTS PR00123 ATP synthase A subunit signature 239 254 3.4E-24 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 L21SP3_RS04425 ed3816f301bfa79195ba2652655e0cfc 260 PRINTS PR00123 ATP synthase A subunit signature 89 105 3.4E-24 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 L21SP3_RS04425 ed3816f301bfa79195ba2652655e0cfc 260 PRINTS PR00123 ATP synthase A subunit signature 184 206 3.4E-24 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 L21SP3_RS04425 ed3816f301bfa79195ba2652655e0cfc 260 Gene3D G3DSA:1.20.120.220 82 258 3.2E-43 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 L21SP3_RS04425 ed3816f301bfa79195ba2652655e0cfc 260 Pfam PF00119 ATP synthase A chain 32 252 2.5E-45 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 L21SP3_RS04425 ed3816f301bfa79195ba2652655e0cfc 260 Hamap MF_01393 ATP synthase subunit a [atpB]. 11 259 13.662 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 L21SP3_RS04425 ed3816f301bfa79195ba2652655e0cfc 260 ProSitePatterns PS00449 ATP synthase a subunit signature. 187 196 - T 09-03-2017 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 L21SP3_RS04425 ed3816f301bfa79195ba2652655e0cfc 260 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 22 253 2.6E-40 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 L21SP3_RS00405 8fd969385b001350627edb78fb1fe43e 440 Gene3D G3DSA:3.40.50.800 340 429 1.8E-19 T 09-03-2017 IPR004154 Anticodon-binding L21SP3_RS00405 8fd969385b001350627edb78fb1fe43e 440 Pfam PF13393 Histidyl-tRNA synthetase 8 315 2.2E-52 T 09-03-2017 L21SP3_RS00405 8fd969385b001350627edb78fb1fe43e 440 Pfam PF03129 Anticodon binding domain 344 429 4.1E-11 T 09-03-2017 IPR004154 Anticodon-binding L21SP3_RS00405 8fd969385b001350627edb78fb1fe43e 440 SUPERFAMILY SSF52954 340 429 3.02E-18 T 09-03-2017 IPR004154 Anticodon-binding L21SP3_RS00405 8fd969385b001350627edb78fb1fe43e 440 SUPERFAMILY SSF55681 2 332 1.1E-69 T 09-03-2017 L21SP3_RS00405 8fd969385b001350627edb78fb1fe43e 440 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 430 26.038 T 09-03-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 L21SP3_RS00405 8fd969385b001350627edb78fb1fe43e 440 PIRSF PIRSF001549 1 431 1.1E-121 T 09-03-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 L21SP3_RS00405 8fd969385b001350627edb78fb1fe43e 440 Gene3D G3DSA:3.30.930.10 240 331 5.1E-78 T 09-03-2017 L21SP3_RS00405 8fd969385b001350627edb78fb1fe43e 440 Gene3D G3DSA:3.30.930.10 1 193 5.1E-78 T 09-03-2017 L21SP3_RS00405 8fd969385b001350627edb78fb1fe43e 440 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 419 1.9E-105 T 09-03-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 L21SP3_RS06300 ab7a506979bbd8213341d7b7c5b02d64 323 Gene3D G3DSA:3.30.700.10 7 76 7.1E-4 T 09-03-2017 L21SP3_RS06300 ab7a506979bbd8213341d7b7c5b02d64 323 SUPERFAMILY SSF54523 7 75 1.94E-11 T 09-03-2017 L21SP3_RS06300 ab7a506979bbd8213341d7b7c5b02d64 323 PRINTS PR00813 Bacterial general secretion pathway protein G signature 6 31 4.4E-5 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS06300 ab7a506979bbd8213341d7b7c5b02d64 323 PRINTS PR00813 Bacterial general secretion pathway protein G signature 42 60 4.4E-5 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS06300 ab7a506979bbd8213341d7b7c5b02d64 323 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 8.4E-4 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 PIRSF PIRSF000099 5 435 1.1E-140 T 09-03-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 Gene3D G3DSA:3.40.50.1980 37 244 1.2E-65 T 09-03-2017 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 Pfam PF00815 Histidinol dehydrogenase 36 432 7.1E-140 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 10 432 35.356 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 PRINTS PR00083 Histidinol dehydrogenase signature 140 166 2.2E-73 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 PRINTS PR00083 Histidinol dehydrogenase signature 234 255 2.2E-73 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 PRINTS PR00083 Histidinol dehydrogenase signature 324 349 2.2E-73 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 PRINTS PR00083 Histidinol dehydrogenase signature 175 201 2.2E-73 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 PRINTS PR00083 Histidinol dehydrogenase signature 205 230 2.2E-73 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 PRINTS PR00083 Histidinol dehydrogenase signature 43 67 2.2E-73 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 PRINTS PR00083 Histidinol dehydrogenase signature 366 384 2.2E-73 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 PRINTS PR00083 Histidinol dehydrogenase signature 256 275 2.2E-73 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 43 431 2.4E-136 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 234 266 - T 09-03-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 L21SP3_RS09100 43903f36883b0b417eb79a00b61221c4 436 SUPERFAMILY SSF53720 37 432 9.61E-65 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 L21SP3_RS09715 ce1b41e27217e81f3acfd1b3391cb1fc 528 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 5 313 2.7E-28 T 09-03-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 L21SP3_RS09715 ce1b41e27217e81f3acfd1b3391cb1fc 528 SUPERFAMILY SSF53649 1 282 1.06E-34 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09715 ce1b41e27217e81f3acfd1b3391cb1fc 528 Gene3D G3DSA:3.40.720.10 2 288 2.8E-42 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS03805 f6380ad5a44a325f8b7d8f44261cb6d3 172 Gene3D G3DSA:1.10.10.10 4 80 6.1E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS03805 f6380ad5a44a325f8b7d8f44261cb6d3 172 SUPERFAMILY SSF46785 4 80 1.88E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS03805 f6380ad5a44a325f8b7d8f44261cb6d3 172 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 5 170 3.2E-43 T 09-03-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 L21SP3_RS03805 f6380ad5a44a325f8b7d8f44261cb6d3 172 Pfam PF04079 Segregation and condensation complex subunit ScpB 8 166 4.4E-58 T 09-03-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 L21SP3_RS03805 f6380ad5a44a325f8b7d8f44261cb6d3 172 SUPERFAMILY SSF46785 84 158 4.54E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS03805 f6380ad5a44a325f8b7d8f44261cb6d3 172 PIRSF PIRSF019345 2 172 1.2E-56 T 09-03-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 L21SP3_RS03805 f6380ad5a44a325f8b7d8f44261cb6d3 172 Gene3D G3DSA:1.10.10.10 83 158 1.0E-32 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS10145 2dd5567fdffdebea9e769728a2aeee61 384 ProSitePatterns PS00194 Thioredoxin family active site. 277 295 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 L21SP3_RS10145 2dd5567fdffdebea9e769728a2aeee61 384 SUPERFAMILY SSF52833 256 381 1.06E-33 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS10145 2dd5567fdffdebea9e769728a2aeee61 384 Gene3D G3DSA:3.40.30.10 255 383 7.6E-47 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS10145 2dd5567fdffdebea9e769728a2aeee61 384 Pfam PF00578 AhpC/TSA family 256 367 2.6E-22 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 L21SP3_RS03085 020185342ff8cf2dd3980a702c88faea 231 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 75 127 2.0E-6 T 09-03-2017 L21SP3_RS03085 020185342ff8cf2dd3980a702c88faea 231 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 70 85 - T 09-03-2017 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 L21SP3_RS03085 020185342ff8cf2dd3980a702c88faea 231 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 25 182 7.6E-36 T 09-03-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 L21SP3_RS03085 020185342ff8cf2dd3980a702c88faea 231 Gene3D G3DSA:3.90.1550.10 3 203 1.0E-51 T 09-03-2017 L21SP3_RS03085 020185342ff8cf2dd3980a702c88faea 231 PIRSF PIRSF016262 1 218 8.9E-51 T 09-03-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 L21SP3_RS03085 020185342ff8cf2dd3980a702c88faea 231 SUPERFAMILY SSF55681 3 205 2.07E-45 T 09-03-2017 L21SP3_RS11685 7bff508c0087acbaf6f8853fcfdf5730 91 Gene3D G3DSA:3.30.70.240 2 72 6.8E-19 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain L21SP3_RS11685 7bff508c0087acbaf6f8853fcfdf5730 91 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 73 1.3E-12 T 09-03-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 L21SP3_RS11685 7bff508c0087acbaf6f8853fcfdf5730 91 SUPERFAMILY SSF143430 2 78 1.57E-15 T 09-03-2017 L21SP3_RS11685 7bff508c0087acbaf6f8853fcfdf5730 91 Pfam PF09827 CRISPR associated protein Cas2 2 73 7.2E-15 T 09-03-2017 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 L21SP3_RS11685 7bff508c0087acbaf6f8853fcfdf5730 91 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 88 10.111 T 09-03-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 L21SP3_RS03140 cd04069ec184a89479967824b62f8ff7 826 Gene3D G3DSA:1.50.10.10 110 316 5.8E-8 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS03140 cd04069ec184a89479967824b62f8ff7 826 SUPERFAMILY SSF48208 106 512 2.96E-32 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS07310 4c817812dbcb84913d435d3f2459f270 231 Pfam PF06508 Queuosine biosynthesis protein QueC 6 222 3.6E-75 T 09-03-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 L21SP3_RS07310 4c817812dbcb84913d435d3f2459f270 231 Gene3D G3DSA:3.40.50.620 4 230 1.0E-74 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS07310 4c817812dbcb84913d435d3f2459f270 231 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 5 228 52.021 T 09-03-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 L21SP3_RS07310 4c817812dbcb84913d435d3f2459f270 231 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 7 215 3.4E-59 T 09-03-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 L21SP3_RS07310 4c817812dbcb84913d435d3f2459f270 231 PIRSF PIRSF006293 3 231 9.2E-78 T 09-03-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 L21SP3_RS07310 4c817812dbcb84913d435d3f2459f270 231 SUPERFAMILY SSF52402 4 230 4.41E-60 T 09-03-2017 L21SP3_RS05325 42b09eec0fe27a2b7870ed902ca3fd13 323 SUPERFAMILY SSF54791 11 62 5.11E-6 T 09-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 L21SP3_RS05325 42b09eec0fe27a2b7870ed902ca3fd13 323 SUPERFAMILY SSF52540 103 284 3.92E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05325 42b09eec0fe27a2b7870ed902ca3fd13 323 Gene3D G3DSA:3.40.50.300 104 307 2.2E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05325 42b09eec0fe27a2b7870ed902ca3fd13 323 Pfam PF02562 PhoH-like protein 104 307 4.4E-86 T 09-03-2017 IPR003714 PhoH-like protein GO:0005524 L21SP3_RS02505 7c1c7a68a65eb33ffeca52e535a958c0 290 SUPERFAMILY SSF51569 1 290 3.45E-95 T 09-03-2017 L21SP3_RS02505 7c1c7a68a65eb33ffeca52e535a958c0 290 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 286 2.3E-111 T 09-03-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS02505 7c1c7a68a65eb33ffeca52e535a958c0 290 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 37 54 - T 09-03-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS02505 7c1c7a68a65eb33ffeca52e535a958c0 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 1.5E-34 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS02505 7c1c7a68a65eb33ffeca52e535a958c0 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 127 144 1.5E-34 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS02505 7c1c7a68a65eb33ffeca52e535a958c0 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 70 88 1.5E-34 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS02505 7c1c7a68a65eb33ffeca52e535a958c0 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 102 118 1.5E-34 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS02505 7c1c7a68a65eb33ffeca52e535a958c0 290 Gene3D G3DSA:3.20.20.70 1 290 1.5E-110 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS02505 7c1c7a68a65eb33ffeca52e535a958c0 290 PIRSF PIRSF001365 1 290 7.5E-84 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS02505 7c1c7a68a65eb33ffeca52e535a958c0 290 Pfam PF00701 Dihydrodipicolinate synthetase family 2 285 8.9E-92 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS02505 7c1c7a68a65eb33ffeca52e535a958c0 290 SMART SM01130 1 288 2.0E-134 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS02505 7c1c7a68a65eb33ffeca52e535a958c0 290 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 286 62.198 T 09-03-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 L21SP3_RS05745 ff8c7386f84db1717972b93b5f7ecce4 743 Pfam PF01228 Glycine radical 618 724 1.2E-40 T 09-03-2017 IPR001150 Glycine radical domain GO:0003824|GO:0008152 L21SP3_RS05745 ff8c7386f84db1717972b93b5f7ecce4 743 Pfam PF02901 Pyruvate formate lyase-like 16 602 2.0E-191 T 09-03-2017 IPR004184 Pyruvate formate lyase domain GO:0003824 L21SP3_RS05745 ff8c7386f84db1717972b93b5f7ecce4 743 SUPERFAMILY SSF51998 2 742 2.38E-267 T 09-03-2017 L21SP3_RS05745 ff8c7386f84db1717972b93b5f7ecce4 743 PIRSF PIRSF000379 1 743 0.0 T 09-03-2017 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 L21SP3_RS05745 ff8c7386f84db1717972b93b5f7ecce4 743 ProSitePatterns PS00850 Glycine radical domain signature. 713 721 - T 09-03-2017 IPR019777 Formate C-acetyltransferase glycine radical, conserved site L21SP3_RS05745 ff8c7386f84db1717972b93b5f7ecce4 743 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 4 742 0.0 T 09-03-2017 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 L21SP3_RS05745 ff8c7386f84db1717972b93b5f7ecce4 743 Gene3D G3DSA:3.20.70.20 2 741 1.6E-290 T 09-03-2017 L21SP3_RS06415 f4c44d86e026e38eef5e59dc698708e3 299 SUPERFAMILY SSF56784 11 286 6.15E-43 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS06415 f4c44d86e026e38eef5e59dc698708e3 299 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 12 80 1.6E-11 T 09-03-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 L21SP3_RS06415 f4c44d86e026e38eef5e59dc698708e3 299 Gene3D G3DSA:3.40.50.1000 11 78 7.0E-35 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS06415 f4c44d86e026e38eef5e59dc698708e3 299 Gene3D G3DSA:3.40.50.1000 182 286 7.0E-35 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS06415 f4c44d86e026e38eef5e59dc698708e3 299 Pfam PF08282 haloacid dehalogenase-like hydrolase 12 282 2.0E-47 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS01845 b7222f5da6990d8ac3a16043b31f3152 473 Gene3D G3DSA:1.20.200.10 101 447 3.2E-117 T 09-03-2017 L21SP3_RS01845 b7222f5da6990d8ac3a16043b31f3152 473 Pfam PF00206 Lyase 38 299 3.1E-21 T 09-03-2017 IPR022761 Fumarate lyase, N-terminal L21SP3_RS01845 b7222f5da6990d8ac3a16043b31f3152 473 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 9 449 5.7E-119 T 09-03-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 L21SP3_RS01845 b7222f5da6990d8ac3a16043b31f3152 473 ProSitePatterns PS00163 Fumarate lyases signature. 279 288 - T 09-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 L21SP3_RS01845 b7222f5da6990d8ac3a16043b31f3152 473 SMART SM00998 368 450 2.6E-22 T 09-03-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 L21SP3_RS01845 b7222f5da6990d8ac3a16043b31f3152 473 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 4.8E-8 T 09-03-2017 IPR000362 Fumarate lyase family L21SP3_RS01845 b7222f5da6990d8ac3a16043b31f3152 473 PRINTS PR00149 Fumarate lyase superfamily signature 142 160 4.8E-8 T 09-03-2017 IPR000362 Fumarate lyase family L21SP3_RS01845 b7222f5da6990d8ac3a16043b31f3152 473 PRINTS PR00149 Fumarate lyase superfamily signature 236 263 4.8E-8 T 09-03-2017 IPR000362 Fumarate lyase family L21SP3_RS01845 b7222f5da6990d8ac3a16043b31f3152 473 Pfam PF10397 Adenylosuccinate lyase C-terminus 369 449 5.2E-17 T 09-03-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 L21SP3_RS01845 b7222f5da6990d8ac3a16043b31f3152 473 SUPERFAMILY SSF48557 7 451 7.07E-93 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 L21SP3_RS01845 b7222f5da6990d8ac3a16043b31f3152 473 Gene3D G3DSA:1.10.275.10 10 100 8.4E-27 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal L21SP3_RS09865 ffebb84aeeb870a5127455f5408de350 225 Pfam PF14103 Domain of unknown function (DUF4276) 10 219 6.4E-48 T 09-03-2017 IPR025455 Protein of unknown function DUF4276 L21SP3_RS04465 363f9a4dc5bb3f9fe6dd3a71b0e09abf 157 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 5 144 12.976 T 09-03-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 L21SP3_RS04465 363f9a4dc5bb3f9fe6dd3a71b0e09abf 157 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 8 90 1.9E-14 T 09-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 L21SP3_RS04465 363f9a4dc5bb3f9fe6dd3a71b0e09abf 157 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 23 88 4.0E-6 T 09-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 L21SP3_RS04465 363f9a4dc5bb3f9fe6dd3a71b0e09abf 157 Gene3D G3DSA:2.60.15.10 7 97 4.0E-14 T 09-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 L21SP3_RS04465 363f9a4dc5bb3f9fe6dd3a71b0e09abf 157 SUPERFAMILY SSF51344 7 91 1.05E-10 T 09-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 L21SP3_RS07535 9d6581e1a9c2792e874cc5011c9d72de 375 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 5 368 6.9E-70 T 09-03-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 L21SP3_RS07535 9d6581e1a9c2792e874cc5011c9d72de 375 Pfam PF02684 Lipid-A-disaccharide synthetase 5 369 1.1E-77 T 09-03-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 L21SP3_RS07535 9d6581e1a9c2792e874cc5011c9d72de 375 SUPERFAMILY SSF53756 58 351 2.3E-29 T 09-03-2017 L21SP3_RS07535 9d6581e1a9c2792e874cc5011c9d72de 375 Gene3D G3DSA:3.40.50.2000 156 282 8.0E-4 T 09-03-2017 L21SP3_RS07730 f12a62eb7810b79dcbb17774cd308901 99 Pfam PF00166 Chaperonin 10 Kd subunit 8 96 5.5E-15 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS07730 f12a62eb7810b79dcbb17774cd308901 99 Gene3D G3DSA:2.30.33.40 8 96 6.4E-13 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS07730 f12a62eb7810b79dcbb17774cd308901 99 SUPERFAMILY SSF50129 7 97 2.35E-13 T 09-03-2017 IPR011032 GroES-like L21SP3_RS07730 f12a62eb7810b79dcbb17774cd308901 99 SMART SM00883 7 96 7.5E-8 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 L21SP3_RS03515 8cd159be93df24d4d3c4915047d2e21e 565 Gene3D G3DSA:3.60.110.10 226 491 5.2E-20 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP3_RS03515 8cd159be93df24d4d3c4915047d2e21e 565 Pfam PF00795 Carbon-nitrogen hydrolase 243 491 2.7E-14 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP3_RS03515 8cd159be93df24d4d3c4915047d2e21e 565 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 56 487 1.2E-70 T 09-03-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 L21SP3_RS03515 8cd159be93df24d4d3c4915047d2e21e 565 SUPERFAMILY SSF56317 224 490 1.44E-24 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP3_RS03515 8cd159be93df24d4d3c4915047d2e21e 565 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 5 536 16.282 T 09-03-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 L21SP3_RS08710 cce49f1d1713e9e9052525dba0dd8a9d 182 Pfam PF02441 Flavoprotein 4 132 4.9E-33 T 09-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 L21SP3_RS08710 cce49f1d1713e9e9052525dba0dd8a9d 182 Gene3D G3DSA:3.40.50.1950 2 180 1.1E-60 T 09-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 L21SP3_RS08710 cce49f1d1713e9e9052525dba0dd8a9d 182 SUPERFAMILY SSF52507 2 178 1.31E-55 T 09-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 L21SP3_RS10015 9f91f20592818d1792452e5b2ff09dd6 809 Gene3D G3DSA:1.50.10.10 160 309 1.9E-18 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS10015 9f91f20592818d1792452e5b2ff09dd6 809 SUPERFAMILY SSF48208 100 422 7.14E-37 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS10015 9f91f20592818d1792452e5b2ff09dd6 809 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 36 573 1.4E-165 T 09-03-2017 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP3_RS06175 d1a2fc06c40ceb08c953f2f74a3ec910 140 PRINTS PR00060 Ribosomal protein L16 signature 43 54 3.8E-34 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06175 d1a2fc06c40ceb08c953f2f74a3ec910 140 PRINTS PR00060 Ribosomal protein L16 signature 59 88 3.8E-34 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06175 d1a2fc06c40ceb08c953f2f74a3ec910 140 PRINTS PR00060 Ribosomal protein L16 signature 89 118 3.8E-34 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06175 d1a2fc06c40ceb08c953f2f74a3ec910 140 PRINTS PR00060 Ribosomal protein L16 signature 25 37 3.8E-34 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06175 d1a2fc06c40ceb08c953f2f74a3ec910 140 SUPERFAMILY SSF54686 3 136 3.14E-52 T 09-03-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06175 d1a2fc06c40ceb08c953f2f74a3ec910 140 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 83 94 - T 09-03-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06175 d1a2fc06c40ceb08c953f2f74a3ec910 140 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 2 135 35.22 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06175 d1a2fc06c40ceb08c953f2f74a3ec910 140 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 3 128 1.2E-55 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06175 d1a2fc06c40ceb08c953f2f74a3ec910 140 Pfam PF00252 Ribosomal protein L16p/L10e 5 132 4.2E-46 T 09-03-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06175 d1a2fc06c40ceb08c953f2f74a3ec910 140 Gene3D G3DSA:3.90.1170.10 23 136 4.3E-48 T 09-03-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS02165 46a1bbf0b15cf0e4eabf5304c1d03e7e 276 Gene3D G3DSA:2.60.120.520 20 130 3.3E-46 T 09-03-2017 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 L21SP3_RS02165 46a1bbf0b15cf0e4eabf5304c1d03e7e 276 Gene3D G3DSA:2.60.120.500 131 276 3.0E-67 T 09-03-2017 IPR027447 5-keto-4-deoxyuronate isomerase, C-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 L21SP3_RS02165 46a1bbf0b15cf0e4eabf5304c1d03e7e 276 Pfam PF04962 KduI/IolB family 40 270 1.8E-31 T 09-03-2017 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 L21SP3_RS02165 46a1bbf0b15cf0e4eabf5304c1d03e7e 276 PIRSF PIRSF006625 1 276 1.5E-120 T 09-03-2017 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 L21SP3_RS02165 46a1bbf0b15cf0e4eabf5304c1d03e7e 276 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 1 276 50.902 T 09-03-2017 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 L21SP3_RS02165 46a1bbf0b15cf0e4eabf5304c1d03e7e 276 SUPERFAMILY SSF51182 1 260 1.82E-95 T 09-03-2017 IPR011051 RmlC-like cupin domain L21SP3_RS00210 2c7012537cdff507c6cb6a59f4335d1d 351 Pfam PF03781 Sulfatase-modifying factor enzyme 1 139 348 1.4E-25 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS00210 2c7012537cdff507c6cb6a59f4335d1d 351 Pfam PF03793 PASTA domain 55 117 2.9E-8 T 09-03-2017 IPR005543 PASTA domain L21SP3_RS00210 2c7012537cdff507c6cb6a59f4335d1d 351 SUPERFAMILY SSF56436 138 348 1.51E-35 T 09-03-2017 IPR016187 C-type lectin fold L21SP3_RS00210 2c7012537cdff507c6cb6a59f4335d1d 351 Gene3D G3DSA:3.90.1580.10 139 349 2.0E-32 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS00210 2c7012537cdff507c6cb6a59f4335d1d 351 SMART SM00740 50 117 2.5E-7 T 09-03-2017 IPR005543 PASTA domain L21SP3_RS10760 933d14bb9bbcfdd53a35d7f5fc275808 129 Gene3D G3DSA:1.20.5.1030 69 125 9.2E-16 T 09-03-2017 L21SP3_RS10760 933d14bb9bbcfdd53a35d7f5fc275808 129 Hamap MF_00422 Protein translocase subunit SecE [secE]. 68 123 10.533 T 09-03-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 L21SP3_RS10760 933d14bb9bbcfdd53a35d7f5fc275808 129 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 72 126 1.9E-14 T 09-03-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 L21SP3_RS10760 933d14bb9bbcfdd53a35d7f5fc275808 129 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 72 121 4.6E-13 T 09-03-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 L21SP3_RS03115 5f7f9c17663fe7cf2e3b4e6952a1a09d 280 Pfam PF00809 Pterin binding enzyme 18 258 1.8E-85 T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 L21SP3_RS03115 5f7f9c17663fe7cf2e3b4e6952a1a09d 280 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 17 271 3.6E-95 T 09-03-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 L21SP3_RS03115 5f7f9c17663fe7cf2e3b4e6952a1a09d 280 Gene3D G3DSA:3.20.20.20 15 274 4.0E-100 T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 L21SP3_RS03115 5f7f9c17663fe7cf2e3b4e6952a1a09d 280 SUPERFAMILY SSF51717 13 273 6.67E-92 T 09-03-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 L21SP3_RS03115 5f7f9c17663fe7cf2e3b4e6952a1a09d 280 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 51 64 - T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 L21SP3_RS03115 5f7f9c17663fe7cf2e3b4e6952a1a09d 280 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 17 32 - T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 L21SP3_RS11620 5b4b8c85e072b4b53216b85bef41872e 353 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 228 234 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 L21SP3_RS11620 5b4b8c85e072b4b53216b85bef41872e 353 SUPERFAMILY SSF53335 133 310 1.33E-44 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS11620 5b4b8c85e072b4b53216b85bef41872e 353 SUPERFAMILY SSF53335 1 84 1.33E-44 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS11620 5b4b8c85e072b4b53216b85bef41872e 353 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 3 313 8.0E-53 T 09-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP3_RS11620 5b4b8c85e072b4b53216b85bef41872e 353 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 29 43 3.0E-13 T 09-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP3_RS11620 5b4b8c85e072b4b53216b85bef41872e 353 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 50 63 3.0E-13 T 09-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP3_RS11620 5b4b8c85e072b4b53216b85bef41872e 353 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 225 237 3.0E-13 T 09-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP3_RS11620 5b4b8c85e072b4b53216b85bef41872e 353 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 3 19 3.0E-13 T 09-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 L21SP3_RS11620 5b4b8c85e072b4b53216b85bef41872e 353 Gene3D G3DSA:3.40.50.150 1 59 3.4E-23 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS11620 5b4b8c85e072b4b53216b85bef41872e 353 Gene3D G3DSA:3.40.50.150 211 303 3.4E-23 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08030 7b71cf561df169ba00edf93962863d1a 365 Gene3D G3DSA:2.115.10.20 41 315 1.9E-43 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS08030 7b71cf561df169ba00edf93962863d1a 365 SUPERFAMILY SSF75005 40 308 3.27E-41 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS08030 7b71cf561df169ba00edf93962863d1a 365 Pfam PF04616 Glycosyl hydrolases family 43 43 303 6.0E-18 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 Gene3D G3DSA:2.60.120.260 19 228 4.3E-79 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 Gene3D G3DSA:2.70.98.10 750 1043 1.8E-87 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 61 239 6.5E-45 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 Gene3D G3DSA:2.60.40.320 633 737 1.1E-29 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 405 430 - T 09-03-2017 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 SUPERFAMILY SSF74650 751 1042 1.57E-81 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 Pfam PF00703 Glycosyl hydrolases family 2 241 353 4.8E-18 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 SMART SM01038 762 1041 2.6E-114 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 468 482 - T 09-03-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 PRINTS PR00132 Glycosyl hydrolase family 2 signature 167 182 1.2E-36 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 PRINTS PR00132 Glycosyl hydrolase family 2 signature 364 378 1.2E-36 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 PRINTS PR00132 Glycosyl hydrolase family 2 signature 395 413 1.2E-36 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 PRINTS PR00132 Glycosyl hydrolase family 2 signature 539 554 1.2E-36 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 PRINTS PR00132 Glycosyl hydrolase family 2 signature 468 483 1.2E-36 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 355 636 6.6E-109 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 SUPERFAMILY SSF49303 241 353 5.76E-25 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 SUPERFAMILY SSF49785 21 239 1.21E-65 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 Pfam PF02929 Beta galactosidase small chain 765 1040 1.6E-74 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 SUPERFAMILY SSF51445 355 633 1.27E-97 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 Pfam PF16353 Domain of unknown function(DUF4981) 647 736 2.7E-24 T 09-03-2017 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 Gene3D G3DSA:3.20.20.80 354 632 2.0E-110 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 SUPERFAMILY SSF49303 629 738 2.88E-26 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS08895 7556bb591d501264d4cae782d5358569 1071 Gene3D G3DSA:2.60.40.320 229 353 5.0E-33 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS01710 e583db9305c6195e42e5b72ca1971950 271 Gene3D G3DSA:2.160.10.10 2 91 1.6E-22 T 09-03-2017 L21SP3_RS01710 e583db9305c6195e42e5b72ca1971950 271 Gene3D G3DSA:1.20.1180.10 203 256 2.8E-7 T 09-03-2017 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 L21SP3_RS01710 e583db9305c6195e42e5b72ca1971950 271 SUPERFAMILY SSF51161 3 255 8.15E-58 T 09-03-2017 IPR011004 Trimeric LpxA-like L21SP3_RS01710 e583db9305c6195e42e5b72ca1971950 271 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 18 46 - T 09-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 L21SP3_RS01710 e583db9305c6195e42e5b72ca1971950 271 PIRSF PIRSF000456 2 270 3.0E-77 T 09-03-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 L21SP3_RS01710 e583db9305c6195e42e5b72ca1971950 271 Gene3D G3DSA:2.160.10.10 92 202 6.7E-19 T 09-03-2017 L21SP3_RS01710 e583db9305c6195e42e5b72ca1971950 271 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 6 257 5.1E-73 T 09-03-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 L21SP3_RS01710 e583db9305c6195e42e5b72ca1971950 271 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 107 141 4.0E-4 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS01710 e583db9305c6195e42e5b72ca1971950 271 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 34 67 2.6E-5 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS01710 e583db9305c6195e42e5b72ca1971950 271 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 2 31 6.8E-7 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS01710 e583db9305c6195e42e5b72ca1971950 271 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 179 256 1.1E-13 T 09-03-2017 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 L21SP3_RS03015 863115533655883d0eab45ae98b20ed2 705 Gene3D G3DSA:3.40.50.200 299 617 7.7E-49 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 L21SP3_RS03015 863115533655883d0eab45ae98b20ed2 705 SUPERFAMILY SSF52743 302 592 1.11E-46 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 L21SP3_RS03015 863115533655883d0eab45ae98b20ed2 705 PRINTS PR00723 Subtilisin serine protease family (S8) signature 316 335 3.8E-14 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related L21SP3_RS03015 863115533655883d0eab45ae98b20ed2 705 PRINTS PR00723 Subtilisin serine protease family (S8) signature 548 564 3.8E-14 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related L21SP3_RS03015 863115533655883d0eab45ae98b20ed2 705 PRINTS PR00723 Subtilisin serine protease family (S8) signature 363 376 3.8E-14 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related L21SP3_RS03015 863115533655883d0eab45ae98b20ed2 705 SUPERFAMILY SSF117074 172 249 2.75E-7 T 09-03-2017 L21SP3_RS03015 863115533655883d0eab45ae98b20ed2 705 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 321 332 - T 09-03-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site L21SP3_RS03015 863115533655883d0eab45ae98b20ed2 705 Pfam PF00082 Subtilase family 316 597 3.5E-28 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 L21SP3_RS03015 863115533655883d0eab45ae98b20ed2 705 Pfam PF07705 CARDB 72 160 1.0E-7 T 09-03-2017 IPR011635 CARDB domain L21SP3_RS03015 863115533655883d0eab45ae98b20ed2 705 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 367 377 - T 09-03-2017 IPR022398 Peptidase S8, subtilisin, His-active site L21SP3_RS03015 863115533655883d0eab45ae98b20ed2 705 SUPERFAMILY SSF63446 650 701 6.15E-5 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS01915 f4543ee75b5711de92476acd35f10297 987 Gene3D G3DSA:2.60.120.260 28 100 7.4E-34 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01915 f4543ee75b5711de92476acd35f10297 987 Gene3D G3DSA:2.60.120.260 137 241 7.4E-34 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01915 f4543ee75b5711de92476acd35f10297 987 Gene3D G3DSA:3.20.20.80 365 675 2.7E-27 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS01915 f4543ee75b5711de92476acd35f10297 987 Pfam PF00703 Glycosyl hydrolases family 2 252 361 6.7E-12 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS01915 f4543ee75b5711de92476acd35f10297 987 Gene3D G3DSA:2.60.40.320 242 361 9.8E-9 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS01915 f4543ee75b5711de92476acd35f10297 987 SUPERFAMILY SSF51445 358 676 2.25E-40 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS01915 f4543ee75b5711de92476acd35f10297 987 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 115 233 7.4E-16 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS01915 f4543ee75b5711de92476acd35f10297 987 SUPERFAMILY SSF49303 252 361 1.7E-6 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS01915 f4543ee75b5711de92476acd35f10297 987 SUPERFAMILY SSF49785 141 247 1.04E-33 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01915 f4543ee75b5711de92476acd35f10297 987 SUPERFAMILY SSF49785 30 81 1.04E-33 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS04145 621a5b30497ff9f742bda72c5aaf2944 285 Pfam PF01694 Rhomboid family 65 209 1.3E-28 T 09-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 L21SP3_RS04145 621a5b30497ff9f742bda72c5aaf2944 285 Gene3D G3DSA:1.20.1540.10 26 208 6.7E-35 T 09-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 L21SP3_RS04145 621a5b30497ff9f742bda72c5aaf2944 285 SUPERFAMILY SSF144091 25 214 1.16E-38 T 09-03-2017 L21SP3_RS09430 0ef7e263888ad1855b7bef1f4d86eab2 355 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 190 326 5.9E-15 T 09-03-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 L21SP3_RS09430 0ef7e263888ad1855b7bef1f4d86eab2 355 Gene3D G3DSA:3.40.50.2000 55 93 0.001 T 09-03-2017 L21SP3_RS09430 0ef7e263888ad1855b7bef1f4d86eab2 355 SUPERFAMILY SSF53756 62 352 4.71E-37 T 09-03-2017 L21SP3_RS09430 0ef7e263888ad1855b7bef1f4d86eab2 355 Gene3D G3DSA:3.40.50.2000 188 352 5.2E-30 T 09-03-2017 L21SP3_RS05870 a9c08f62faf8eb071016d4e540ae6310 199 Pfam PF07589 PEP-CTERM motif 172 194 7.2E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS05870 a9c08f62faf8eb071016d4e540ae6310 199 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 172 195 4.4E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS03740 cf0e604c4aade6f459df24cdd68a4ef8 388 SUPERFAMILY SSF53756 6 383 6.28E-59 T 09-03-2017 L21SP3_RS03740 cf0e604c4aade6f459df24cdd68a4ef8 388 Gene3D G3DSA:3.40.50.2000 205 361 1.3E-27 T 09-03-2017 L21SP3_RS03740 cf0e604c4aade6f459df24cdd68a4ef8 388 Pfam PF00534 Glycosyl transferases group 1 207 360 2.0E-33 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS05750 3680962c3d206dd0d51bfa9f4df09466 387 TIGRFAM TIGR03402 FeS_nifS: cysteine desulfurase NifS 4 382 1.4E-189 T 09-03-2017 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal GO:0006520|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 L21SP3_RS05750 3680962c3d206dd0d51bfa9f4df09466 387 SUPERFAMILY SSF53383 2 375 1.97E-112 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS05750 3680962c3d206dd0d51bfa9f4df09466 387 PIRSF PIRSF005572 1 380 6.3E-137 T 09-03-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 L21SP3_RS05750 3680962c3d206dd0d51bfa9f4df09466 387 Gene3D G3DSA:3.40.640.10 16 247 5.4E-88 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS05750 3680962c3d206dd0d51bfa9f4df09466 387 Gene3D G3DSA:3.90.1150.10 248 370 1.6E-48 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS05750 3680962c3d206dd0d51bfa9f4df09466 387 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 192 211 - T 09-03-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site L21SP3_RS05750 3680962c3d206dd0d51bfa9f4df09466 387 Pfam PF00266 Aminotransferase class-V 4 365 6.1E-95 T 09-03-2017 IPR000192 Aminotransferase class V domain L21SP3_RS10395 b87244eec41db2fa7039c86dd7835856 156 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 L21SP3_RS10395 b87244eec41db2fa7039c86dd7835856 156 Gene3D G3DSA:3.90.79.10 10 146 1.8E-44 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 L21SP3_RS10395 b87244eec41db2fa7039c86dd7835856 156 SUPERFAMILY SSF55811 9 150 6.09E-33 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 L21SP3_RS10395 b87244eec41db2fa7039c86dd7835856 156 Pfam PF00293 NUDIX domain 23 131 5.3E-19 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 L21SP3_RS03750 9fae7ae89c65529840f06795ad3eb87c 279 Pfam PF00535 Glycosyl transferase family 2 6 125 2.3E-15 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 L21SP3_RS03750 9fae7ae89c65529840f06795ad3eb87c 279 Gene3D G3DSA:3.90.550.10 3 213 2.6E-33 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS03750 9fae7ae89c65529840f06795ad3eb87c 279 SUPERFAMILY SSF53448 1 203 2.19E-33 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS04800 a65ef72c3a2498e520eea75159f3c915 370 SUPERFAMILY SSF53756 59 362 8.79E-39 T 09-03-2017 L21SP3_RS04800 a65ef72c3a2498e520eea75159f3c915 370 Pfam PF00534 Glycosyl transferases group 1 186 337 8.1E-19 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS04800 a65ef72c3a2498e520eea75159f3c915 370 Gene3D G3DSA:3.40.50.2000 155 344 4.3E-15 T 09-03-2017 L21SP3_RS08520 46ecaa855ac68db7813d5a11c93d0cfc 259 Pfam PF02654 Cobalamin-5-phosphate synthase 12 249 2.2E-44 T 09-03-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 L21SP3_RS08520 46ecaa855ac68db7813d5a11c93d0cfc 259 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 259 37.281 T 09-03-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 L21SP3_RS03465 ee826fba36993af79cb79b381f5e734e 246 SMART SM00072 1 228 4.0E-4 T 09-03-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit L21SP3_RS03465 ee826fba36993af79cb79b381f5e734e 246 Pfam PF00625 Guanylate kinase 2 72 6.1E-9 T 09-03-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit L21SP3_RS03465 ee826fba36993af79cb79b381f5e734e 246 Gene3D G3DSA:3.40.50.300 2 32 1.4E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03465 ee826fba36993af79cb79b381f5e734e 246 Gene3D G3DSA:3.40.50.300 116 202 1.4E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03465 ee826fba36993af79cb79b381f5e734e 246 SUPERFAMILY SSF52540 169 202 2.63E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03465 ee826fba36993af79cb79b381f5e734e 246 SUPERFAMILY SSF52540 2 141 2.63E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03465 ee826fba36993af79cb79b381f5e734e 246 Gene3D G3DSA:3.30.63.10 36 72 5.4E-8 T 09-03-2017 L21SP3_RS08175 6985593eed14ade6662be5a65d99f735 334 Gene3D G3DSA:2.40.30.10 252 332 6.0E-18 T 09-03-2017 L21SP3_RS08175 6985593eed14ade6662be5a65d99f735 334 SUPERFAMILY SSF52402 1 221 8.38E-50 T 09-03-2017 L21SP3_RS08175 6985593eed14ade6662be5a65d99f735 334 Gene3D G3DSA:3.40.50.620 1 186 2.8E-67 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS08175 6985593eed14ade6662be5a65d99f735 334 Gene3D G3DSA:2.30.30.280 194 250 1.2E-14 T 09-03-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 L21SP3_RS08175 6985593eed14ade6662be5a65d99f735 334 Pfam PF03054 tRNA methyl transferase 1 319 1.8E-98 T 09-03-2017 L21SP3_RS08175 6985593eed14ade6662be5a65d99f735 334 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 332 35.085 T 09-03-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 L21SP3_RS08175 6985593eed14ade6662be5a65d99f735 334 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 319 1.5E-93 T 09-03-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 L21SP3_RS11075 a97db97cf608be86ddc7b4b8e59047b7 664 SUPERFAMILY SSF49785 518 661 3.89E-10 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS11075 a97db97cf608be86ddc7b4b8e59047b7 664 Gene3D G3DSA:2.60.120.260 549 663 2.4E-13 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS11075 a97db97cf608be86ddc7b4b8e59047b7 664 SUPERFAMILY SSF52266 105 208 3.11E-65 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS11075 a97db97cf608be86ddc7b4b8e59047b7 664 SUPERFAMILY SSF52266 280 464 3.11E-65 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS11075 a97db97cf608be86ddc7b4b8e59047b7 664 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 105 402 1.0E-72 T 09-03-2017 IPR005181 Sialate O-acetylesterase domain L21SP3_RS05565 64b2919086d8b5c14582754c870b2c24 258 Pfam PF01343 Peptidase family S49 212 256 1.3E-14 T 09-03-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 L21SP3_RS05565 64b2919086d8b5c14582754c870b2c24 258 Gene3D G3DSA:3.90.226.10 150 255 1.7E-29 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS05565 64b2919086d8b5c14582754c870b2c24 258 SUPERFAMILY SSF52096 145 255 1.06E-26 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS04455 ee75ee80b436f645f1c01fed969766b6 297 Gene3D G3DSA:1.10.287.80 2 36 1.2E-35 T 09-03-2017 L21SP3_RS04455 ee75ee80b436f645f1c01fed969766b6 297 Gene3D G3DSA:1.10.287.80 230 296 1.2E-35 T 09-03-2017 L21SP3_RS04455 ee75ee80b436f645f1c01fed969766b6 297 Gene3D G3DSA:3.40.1380.10 64 192 1.3E-31 T 09-03-2017 L21SP3_RS04455 ee75ee80b436f645f1c01fed969766b6 297 SUPERFAMILY SSF52943 2 296 3.14E-63 T 09-03-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 L21SP3_RS04455 ee75ee80b436f645f1c01fed969766b6 297 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 4.3E-25 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 L21SP3_RS04455 ee75ee80b436f645f1c01fed969766b6 297 PRINTS PR00126 ATP synthase gamma subunit signature 243 262 4.3E-25 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 L21SP3_RS04455 ee75ee80b436f645f1c01fed969766b6 297 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 4.3E-25 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 L21SP3_RS04455 ee75ee80b436f645f1c01fed969766b6 297 PRINTS PR00126 ATP synthase gamma subunit signature 274 295 4.3E-25 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 L21SP3_RS04455 ee75ee80b436f645f1c01fed969766b6 297 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 296 8.2E-69 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 L21SP3_RS04455 ee75ee80b436f645f1c01fed969766b6 297 Pfam PF00231 ATP synthase 4 296 1.3E-67 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 L21SP3_RS04455 ee75ee80b436f645f1c01fed969766b6 297 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 296 25.639 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 L21SP3_RS11690 fee196a278188a43d6b0131e9c54c933 319 TIGRFAM TIGR04329 cas1_PREFRAN: CRISPR-associated endonuclease Cas1, subtype PREFRAN 6 318 4.7E-123 T 09-03-2017 IPR027617 CRISPR-associated endonuclease Cas1, PREFRAN subtype GO:0004520|GO:0043571|GO:0046872 L21SP3_RS11690 fee196a278188a43d6b0131e9c54c933 319 Pfam PF01867 CRISPR associated protein Cas1 18 267 6.1E-50 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 L21SP3_RS11690 fee196a278188a43d6b0131e9c54c933 319 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 16 265 8.4E-43 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 L21SP3_RS11690 fee196a278188a43d6b0131e9c54c933 319 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 10 307 17.538 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 L21SP3_RS09255 bc425ac37aff496d519b5ffc1816d2ba 338 Gene3D G3DSA:1.25.40.10 82 215 9.9E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS09255 bc425ac37aff496d519b5ffc1816d2ba 338 SUPERFAMILY SSF48452 74 194 1.87E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS09255 bc425ac37aff496d519b5ffc1816d2ba 338 SUPERFAMILY SSF48452 256 298 1.87E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS09255 bc425ac37aff496d519b5ffc1816d2ba 338 Pfam PF13525 Outer membrane lipoprotein 142 310 6.9E-6 T 09-03-2017 L21SP3_RS08505 c841f3eedb1296ed055aa7dcc4fed1f9 537 SUPERFAMILY SSF63446 471 530 1.83E-7 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS08505 c841f3eedb1296ed055aa7dcc4fed1f9 537 Gene3D G3DSA:1.10.1330.10 472 530 9.0E-7 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS05990 9f2845d53336a21028dd54761b6f528c 667 SMART SM00409 309 399 1.0E-6 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS05990 9f2845d53336a21028dd54761b6f528c 667 SUPERFAMILY SSF49899 7 161 4.16E-10 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05990 9f2845d53336a21028dd54761b6f528c 667 SUPERFAMILY SSF49899 405 618 2.55E-28 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05990 9f2845d53336a21028dd54761b6f528c 667 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 105 161 1.2E-6 T 09-03-2017 L21SP3_RS05990 9f2845d53336a21028dd54761b6f528c 667 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 446 613 1.5E-23 T 09-03-2017 L21SP3_RS05990 9f2845d53336a21028dd54761b6f528c 667 SMART SM00560 468 610 0.0057 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS05990 9f2845d53336a21028dd54761b6f528c 667 SUPERFAMILY SSF48726 305 398 3.16E-13 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS05990 9f2845d53336a21028dd54761b6f528c 667 Pfam PF07679 Immunoglobulin I-set domain 306 396 1.5E-8 T 09-03-2017 IPR013098 Immunoglobulin I-set L21SP3_RS05990 9f2845d53336a21028dd54761b6f528c 667 Gene3D G3DSA:2.60.120.200 446 619 8.0E-28 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05990 9f2845d53336a21028dd54761b6f528c 667 Gene3D G3DSA:2.60.120.200 7 161 3.6E-9 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05990 9f2845d53336a21028dd54761b6f528c 667 Gene3D G3DSA:2.60.40.10 307 399 1.8E-13 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS11230 c27b9ba5de6fd20274db8aa5d73232f3 602 Gene3D G3DSA:3.40.449.10 4 242 6.4E-93 T 09-03-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 L21SP3_RS11230 c27b9ba5de6fd20274db8aa5d73232f3 602 SUPERFAMILY SSF53795 243 601 5.49E-154 T 09-03-2017 L21SP3_RS11230 c27b9ba5de6fd20274db8aa5d73232f3 602 SUPERFAMILY SSF68923 4 242 3.03E-97 T 09-03-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 L21SP3_RS11230 c27b9ba5de6fd20274db8aa5d73232f3 602 PIRSF PIRSF001348 2 602 5.7E-275 T 09-03-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 L21SP3_RS11230 c27b9ba5de6fd20274db8aa5d73232f3 602 Gene3D G3DSA:3.90.228.20 329 601 1.6E-93 T 09-03-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 L21SP3_RS11230 c27b9ba5de6fd20274db8aa5d73232f3 602 Gene3D G3DSA:3.90.228.20 243 312 3.3E-33 T 09-03-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 L21SP3_RS11230 c27b9ba5de6fd20274db8aa5d73232f3 602 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 267 275 - T 09-03-2017 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 L21SP3_RS11230 c27b9ba5de6fd20274db8aa5d73232f3 602 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 8 601 46.844 T 09-03-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 L21SP3_RS11230 c27b9ba5de6fd20274db8aa5d73232f3 602 Pfam PF00821 Phosphoenolpyruvate carboxykinase 19 600 8.2E-271 T 09-03-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 L21SP3_RS00120 5d186edcf3c7b88fbbb6f47799513566 229 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 29 227 21.714 T 09-03-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 L21SP3_RS00120 5d186edcf3c7b88fbbb6f47799513566 229 Pfam PF01121 Dephospho-CoA kinase 31 207 1.9E-38 T 09-03-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 L21SP3_RS00120 5d186edcf3c7b88fbbb6f47799513566 229 SUPERFAMILY SSF52540 31 222 3.09E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00120 5d186edcf3c7b88fbbb6f47799513566 229 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 31 218 6.4E-39 T 09-03-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 L21SP3_RS00120 5d186edcf3c7b88fbbb6f47799513566 229 Gene3D G3DSA:3.40.50.300 24 226 6.9E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10255 f6b610c4636d351496a123dababb6b16 300 Gene3D G3DSA:3.40.50.300 2 222 5.3E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10255 f6b610c4636d351496a123dababb6b16 300 SMART SM00382 29 209 7.3E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS10255 f6b610c4636d351496a123dababb6b16 300 SUPERFAMILY SSF52540 3 222 3.03E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10255 f6b610c4636d351496a123dababb6b16 300 Pfam PF00005 ABC transporter 20 158 7.3E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS11535 924692958cb07ba1c1184b6990bb9acf 1602 Gene3D G3DSA:3.40.50.10390 243 379 1.1E-12 T 09-03-2017 IPR029031 Gingipain, N-terminal L21SP3_RS11535 924692958cb07ba1c1184b6990bb9acf 1602 Pfam PF08126 Propeptide_C25 51 174 1.8E-7 T 09-03-2017 IPR012600 Gingipain propeptide GO:0004197 L21SP3_RS11535 924692958cb07ba1c1184b6990bb9acf 1602 Gene3D G3DSA:2.60.40.10 1188 1272 2.3E-9 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS11535 924692958cb07ba1c1184b6990bb9acf 1602 SUPERFAMILY SSF52129 240 544 3.77E-11 T 09-03-2017 IPR029030 Caspase-like domain L21SP3_RS11535 924692958cb07ba1c1184b6990bb9acf 1602 Gene3D G3DSA:3.40.50.1460 383 544 2.8E-4 T 09-03-2017 IPR029030 Caspase-like domain L21SP3_RS11535 924692958cb07ba1c1184b6990bb9acf 1602 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 779 930 4.5E-13 T 09-03-2017 L21SP3_RS11535 924692958cb07ba1c1184b6990bb9acf 1602 ProSitePatterns PS00018 EF-hand calcium-binding domain. 1578 1590 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS11535 924692958cb07ba1c1184b6990bb9acf 1602 Gene3D G3DSA:2.60.120.200 725 932 1.7E-24 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS11535 924692958cb07ba1c1184b6990bb9acf 1602 SUPERFAMILY SSF49899 728 933 2.64E-26 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS11260 d5b5acf1540158e21bfaa7f98677333f 202 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 27 103 1.1E-19 T 09-03-2017 IPR025159 Transcriptional regulator, AbiEi antitoxin L21SP3_RS11005 e58b6069250073914a6c5db78c1a58f3 234 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 122 201 1.4E-13 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP3_RS11005 e58b6069250073914a6c5db78c1a58f3 234 SUPERFAMILY SSF56784 2 225 1.85E-45 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS11005 e58b6069250073914a6c5db78c1a58f3 234 Gene3D G3DSA:1.10.150.240 17 86 7.2E-5 T 09-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 L21SP3_RS11005 e58b6069250073914a6c5db78c1a58f3 234 Gene3D G3DSA:3.40.50.1000 1 16 2.9E-40 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS11005 e58b6069250073914a6c5db78c1a58f3 234 Gene3D G3DSA:3.40.50.1000 93 226 2.9E-40 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS11005 e58b6069250073914a6c5db78c1a58f3 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 201 1.5E-27 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS09340 084f0598e7530589239614140ff5a46e 391 Gene3D G3DSA:3.40.50.2300 26 119 4.6E-11 T 09-03-2017 L21SP3_RS09340 084f0598e7530589239614140ff5a46e 391 Gene3D G3DSA:3.40.50.2300 120 255 3.6E-24 T 09-03-2017 L21SP3_RS09340 084f0598e7530589239614140ff5a46e 391 SUPERFAMILY SSF46689 341 388 4.48E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS09340 084f0598e7530589239614140ff5a46e 391 Gene3D G3DSA:1.10.10.60 285 333 5.2E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS09340 084f0598e7530589239614140ff5a46e 391 SMART SM00342 302 385 2.3E-15 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS09340 084f0598e7530589239614140ff5a46e 391 Gene3D G3DSA:1.10.10.60 342 388 1.6E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS09340 084f0598e7530589239614140ff5a46e 391 Pfam PF13377 Periplasmic binding protein-like domain 115 278 1.6E-29 T 09-03-2017 L21SP3_RS09340 084f0598e7530589239614140ff5a46e 391 SUPERFAMILY SSF53822 22 298 1.99E-39 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS09340 084f0598e7530589239614140ff5a46e 391 Pfam PF12833 Helix-turn-helix domain 308 386 2.9E-14 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS01735 4763dc1384d9ab3270f24e23151accf3 227 Pfam PF02310 B12 binding domain 106 201 1.0E-13 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 L21SP3_RS01735 4763dc1384d9ab3270f24e23151accf3 227 Pfam PF02607 B12 binding domain 21 85 3.6E-9 T 09-03-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 L21SP3_RS01735 4763dc1384d9ab3270f24e23151accf3 227 Gene3D G3DSA:3.40.50.280 106 198 3.6E-13 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 L21SP3_RS01735 4763dc1384d9ab3270f24e23151accf3 227 SUPERFAMILY SSF52242 103 197 1.88E-15 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 L21SP3_RS04890 00496a333f5655a2bd34d22a05202e94 112 Pfam PF01909 Nucleotidyltransferase domain 15 54 1.1E-10 T 09-03-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 L21SP3_RS04890 00496a333f5655a2bd34d22a05202e94 112 SUPERFAMILY SSF81301 6 111 8.92E-13 T 09-03-2017 L21SP3_RS04890 00496a333f5655a2bd34d22a05202e94 112 Gene3D G3DSA:3.30.460.10 8 110 8.2E-16 T 09-03-2017 L21SP3_RS06110 3533fb17ae0ac2b1df93e1a8d1fb2fd4 214 SUPERFAMILY SSF52540 1 212 4.91E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06110 3533fb17ae0ac2b1df93e1a8d1fb2fd4 214 Pfam PF05191 Adenylate kinase, active site lid 125 160 8.4E-18 T 09-03-2017 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 L21SP3_RS06110 3533fb17ae0ac2b1df93e1a8d1fb2fd4 214 ProSitePatterns PS00113 Adenylate kinase signature. 79 90 - T 09-03-2017 L21SP3_RS06110 3533fb17ae0ac2b1df93e1a8d1fb2fd4 214 TIGRFAM TIGR01351 adk: adenylate kinase 3 211 8.5E-75 T 09-03-2017 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 L21SP3_RS06110 3533fb17ae0ac2b1df93e1a8d1fb2fd4 214 Gene3D G3DSA:3.40.50.300 1 210 6.7E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06110 3533fb17ae0ac2b1df93e1a8d1fb2fd4 214 Hamap MF_00235 Adenylate kinase [adk]. 1 212 45.446 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 L21SP3_RS06110 3533fb17ae0ac2b1df93e1a8d1fb2fd4 214 PRINTS PR00094 Adenylate kinase signature 79 95 1.3E-30 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 L21SP3_RS06110 3533fb17ae0ac2b1df93e1a8d1fb2fd4 214 PRINTS PR00094 Adenylate kinase signature 175 189 1.3E-30 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 L21SP3_RS06110 3533fb17ae0ac2b1df93e1a8d1fb2fd4 214 PRINTS PR00094 Adenylate kinase signature 158 173 1.3E-30 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 L21SP3_RS06110 3533fb17ae0ac2b1df93e1a8d1fb2fd4 214 PRINTS PR00094 Adenylate kinase signature 4 17 1.3E-30 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 L21SP3_RS06110 3533fb17ae0ac2b1df93e1a8d1fb2fd4 214 PRINTS PR00094 Adenylate kinase signature 32 46 1.3E-30 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 L21SP3_RS06110 3533fb17ae0ac2b1df93e1a8d1fb2fd4 214 Pfam PF00406 Adenylate kinase 5 187 4.2E-53 T 09-03-2017 L21SP3_RS03440 93016d0c5b6ce5c573793fbca572134a 480 SUPERFAMILY SSF51445 175 474 2.98E-25 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS03440 93016d0c5b6ce5c573793fbca572134a 480 Gene3D G3DSA:3.20.20.80 174 474 2.2E-29 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS08045 37b7a389374a6c45c8d271a3cfa7d839 438 Hamap MF_00900 GTPase HflX [hflX]. 33 403 40.905 T 09-03-2017 IPR016496 GTPase HflX GO:0005525 L21SP3_RS08045 37b7a389374a6c45c8d271a3cfa7d839 438 Pfam PF16360 GTP-binding GTPase Middle Region 120 208 1.2E-26 T 09-03-2017 IPR032305 GTP-binding protein, middle domain L21SP3_RS08045 37b7a389374a6c45c8d271a3cfa7d839 438 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 15 373 4.3E-123 T 09-03-2017 IPR016496 GTPase HflX GO:0005525 L21SP3_RS08045 37b7a389374a6c45c8d271a3cfa7d839 438 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 214 234 1.7E-6 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS08045 37b7a389374a6c45c8d271a3cfa7d839 438 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 281 299 1.7E-6 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS08045 37b7a389374a6c45c8d271a3cfa7d839 438 PIRSF PIRSF006809 6 433 5.5E-127 T 09-03-2017 IPR016496 GTPase HflX GO:0005525 L21SP3_RS08045 37b7a389374a6c45c8d271a3cfa7d839 438 Gene3D G3DSA:3.40.50.300 212 374 2.4E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08045 37b7a389374a6c45c8d271a3cfa7d839 438 Pfam PF13167 GTP-binding GTPase N-terminal 31 118 3.7E-27 T 09-03-2017 IPR025121 GTPase HflX, N-terminal L21SP3_RS08045 37b7a389374a6c45c8d271a3cfa7d839 438 SUPERFAMILY SSF52540 212 384 3.56E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08045 37b7a389374a6c45c8d271a3cfa7d839 438 Pfam PF01926 50S ribosome-binding GTPase 213 332 3.0E-17 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS05450 d849783c10c4ca9d8cfd58ce3a7cc22c 398 Gene3D G3DSA:3.40.50.300 3 263 6.1E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05450 d849783c10c4ca9d8cfd58ce3a7cc22c 398 SMART SM00382 52 249 3.2E-19 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS05450 d849783c10c4ca9d8cfd58ce3a7cc22c 398 Pfam PF00571 CBS domain 276 328 1.4E-4 T 09-03-2017 IPR000644 CBS domain L21SP3_RS05450 d849783c10c4ca9d8cfd58ce3a7cc22c 398 SUPERFAMILY SSF54631 273 390 6.01E-19 T 09-03-2017 L21SP3_RS05450 d849783c10c4ca9d8cfd58ce3a7cc22c 398 SUPERFAMILY SSF52540 42 269 1.06E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05450 d849783c10c4ca9d8cfd58ce3a7cc22c 398 Pfam PF00005 ABC transporter 44 191 9.8E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS05450 d849783c10c4ca9d8cfd58ce3a7cc22c 398 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS05450 d849783c10c4ca9d8cfd58ce3a7cc22c 398 Gene3D G3DSA:3.10.580.10 264 393 2.7E-21 T 09-03-2017 L21SP3_RS05450 d849783c10c4ca9d8cfd58ce3a7cc22c 398 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 390 1.5E-131 T 09-03-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 L21SP3_RS11185 35c4531bedc87a812f664000f166b6b4 603 SUPERFAMILY SSF89000 307 461 5.89E-37 T 09-03-2017 L21SP3_RS11185 35c4531bedc87a812f664000f166b6b4 603 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 558 575 - T 09-03-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 L21SP3_RS11185 35c4531bedc87a812f664000f166b6b4 603 Gene3D G3DSA:3.20.20.70 2 289 3.5E-68 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS11185 35c4531bedc87a812f664000f166b6b4 603 SUPERFAMILY SSF51569 3 293 1.23E-55 T 09-03-2017 L21SP3_RS11185 35c4531bedc87a812f664000f166b6b4 603 SUPERFAMILY SSF51230 528 601 3.66E-20 T 09-03-2017 IPR011053 Single hybrid motif L21SP3_RS11185 35c4531bedc87a812f664000f166b6b4 603 Pfam PF00364 Biotin-requiring enzyme 542 601 9.6E-17 T 09-03-2017 IPR000089 Biotin/lipoyl attachment L21SP3_RS11185 35c4531bedc87a812f664000f166b6b4 603 Pfam PF02436 Conserved carboxylase domain 306 495 2.1E-39 T 09-03-2017 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 L21SP3_RS11185 35c4531bedc87a812f664000f166b6b4 603 Pfam PF00682 HMGL-like 8 280 1.2E-16 T 09-03-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 L21SP3_RS11185 35c4531bedc87a812f664000f166b6b4 603 Gene3D G3DSA:2.40.50.100 532 601 1.6E-23 T 09-03-2017 L21SP3_RS09475 5a2424a3768bf09ecdaad0eaf196762c 170 Pfam PF00583 Acetyltransferase (GNAT) family 66 140 1.4E-14 T 09-03-2017 IPR000182 GNAT domain GO:0008080 L21SP3_RS09475 5a2424a3768bf09ecdaad0eaf196762c 170 Gene3D G3DSA:3.40.630.30 14 152 7.2E-27 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS09475 5a2424a3768bf09ecdaad0eaf196762c 170 SUPERFAMILY SSF55729 18 164 5.93E-24 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 Gene3D G3DSA:1.10.287.130 790 862 2.9E-6 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 655 783 6.1E-6 T 09-03-2017 IPR000014 PAS domain L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 SMART SM00091 659 727 0.0036 T 09-03-2017 IPR000014 PAS domain L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 SUPERFAMILY SSF55785 647 775 5.44E-10 T 09-03-2017 IPR000014 PAS domain L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 Gene3D G3DSA:3.30.565.10 868 1016 9.8E-39 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 SUPERFAMILY SSF55874 855 1016 9.56E-40 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 SUPERFAMILY SSF47384 784 864 7.06E-12 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 Pfam PF13188 PAS domain 368 430 0.0031 T 09-03-2017 IPR000014 PAS domain L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 Pfam PF13188 PAS domain 659 719 8.9E-4 T 09-03-2017 IPR000014 PAS domain L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 SUPERFAMILY SSF55781 210 349 7.11E-6 T 09-03-2017 IPR029016 GAF domain-like L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1003 1016 6.7E-12 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 979 997 6.7E-12 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 946 960 6.7E-12 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 SMART SM00388 797 866 1.7E-5 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 Gene3D G3DSA:3.30.450.20 650 775 2.7E-12 T 09-03-2017 L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 908 1016 1.5E-22 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 SMART SM00387 907 1017 4.2E-28 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain L21SP3_RS11105 1f1399e07128f15e21d645583e7a0f29 1017 Gene3D G3DSA:3.30.450.40 189 349 1.9E-8 T 09-03-2017 IPR029016 GAF domain-like L21SP3_RS10750 1c678104e873dad83a9e20188483a259 55 Pfam PF00471 Ribosomal protein L33 8 51 3.0E-13 T 09-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS10750 1c678104e873dad83a9e20188483a259 55 SUPERFAMILY SSF57829 6 51 5.04E-11 T 09-03-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 L21SP3_RS10750 1c678104e873dad83a9e20188483a259 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 51 7.1E-13 T 09-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS10750 1c678104e873dad83a9e20188483a259 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 54 12.873 T 09-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS08990 b4fe506af432a811882b7af13645ebcf 340 SUPERFAMILY SSF110849 76 166 5.75E-28 T 09-03-2017 IPR003115 ParB/Sulfiredoxin L21SP3_RS08990 b4fe506af432a811882b7af13645ebcf 340 Gene3D G3DSA:3.90.1530.10 69 170 3.9E-38 T 09-03-2017 L21SP3_RS08990 b4fe506af432a811882b7af13645ebcf 340 SUPERFAMILY SSF109709 156 264 1.62E-33 T 09-03-2017 L21SP3_RS08990 b4fe506af432a811882b7af13645ebcf 340 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 73 248 1.2E-55 T 09-03-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 L21SP3_RS08990 b4fe506af432a811882b7af13645ebcf 340 Pfam PF02195 ParB-like nuclease domain 78 164 4.7E-26 T 09-03-2017 IPR003115 ParB/Sulfiredoxin L21SP3_RS08990 b4fe506af432a811882b7af13645ebcf 340 SMART SM00470 75 164 3.5E-32 T 09-03-2017 IPR003115 ParB/Sulfiredoxin L21SP3_RS02250 9edb0487a6bf9bed9264d351258794e4 182 Gene3D G3DSA:1.10.1740.10 15 107 1.1E-16 T 09-03-2017 L21SP3_RS02250 9edb0487a6bf9bed9264d351258794e4 182 TIGRFAM TIGR02989 Sig-70_gvs1: RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family 16 172 2.2E-42 T 09-03-2017 IPR014331 RNA polymerase sigma-70 ECF-like, Rhodopirellula baltica L21SP3_RS02250 9edb0487a6bf9bed9264d351258794e4 182 SUPERFAMILY SSF88659 107 172 1.08E-5 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS02250 9edb0487a6bf9bed9264d351258794e4 182 SUPERFAMILY SSF88946 16 98 6.67E-15 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS02250 9edb0487a6bf9bed9264d351258794e4 182 Pfam PF04542 Sigma-70 region 2 21 87 1.2E-7 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS02250 9edb0487a6bf9bed9264d351258794e4 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 171 3.3E-14 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS11275 f9b71f27484753dabdac77b58525d020 308 SUPERFAMILY SSF55120 83 304 3.6E-62 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS11275 f9b71f27484753dabdac77b58525d020 308 Pfam PF00849 RNA pseudouridylate synthase 99 248 1.0E-28 T 09-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS11275 f9b71f27484753dabdac77b58525d020 308 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 27 304 1.9E-75 T 09-03-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS11275 f9b71f27484753dabdac77b58525d020 308 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 139 153 - T 09-03-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS11275 f9b71f27484753dabdac77b58525d020 308 SUPERFAMILY SSF55174 28 110 2.35E-9 T 09-03-2017 L21SP3_RS11275 f9b71f27484753dabdac77b58525d020 308 Pfam PF01479 S4 domain 29 75 4.8E-9 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS11275 f9b71f27484753dabdac77b58525d020 308 Gene3D G3DSA:3.10.290.10 29 77 9.0E-11 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS11275 f9b71f27484753dabdac77b58525d020 308 SMART SM00363 29 88 1.8E-9 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 L21SP3_RS06180 6183d26b530eeee65e0a54319b3fed3d 242 ProSitePatterns PS00548 Ribosomal protein S3 signature. 167 201 - T 09-03-2017 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06180 6183d26b530eeee65e0a54319b3fed3d 242 SUPERFAMILY SSF54821 113 209 1.15E-33 T 09-03-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06180 6183d26b530eeee65e0a54319b3fed3d 242 SMART SM00322 64 129 1.6E-7 T 09-03-2017 IPR004087 K Homology domain GO:0003676 L21SP3_RS06180 6183d26b530eeee65e0a54319b3fed3d 242 SUPERFAMILY SSF54814 2 110 4.49E-30 T 09-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 L21SP3_RS06180 6183d26b530eeee65e0a54319b3fed3d 242 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 210 33.155 T 09-03-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 L21SP3_RS06180 6183d26b530eeee65e0a54319b3fed3d 242 Gene3D G3DSA:3.30.300.20 17 111 2.8E-28 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta L21SP3_RS06180 6183d26b530eeee65e0a54319b3fed3d 242 Gene3D G3DSA:3.30.1140.32 114 210 1.8E-35 T 09-03-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06180 6183d26b530eeee65e0a54319b3fed3d 242 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 211 5.5E-79 T 09-03-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 L21SP3_RS06180 6183d26b530eeee65e0a54319b3fed3d 242 Pfam PF07650 KH domain 38 113 2.2E-16 T 09-03-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06180 6183d26b530eeee65e0a54319b3fed3d 242 Pfam PF00189 Ribosomal protein S3, C-terminal domain 124 206 2.3E-32 T 09-03-2017 L21SP3_RS05310 ea004baf64728d008b0ba2998c202020 63 Gene3D G3DSA:1.10.10.10 8 60 6.3E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS05310 ea004baf64728d008b0ba2998c202020 63 SUPERFAMILY SSF46955 6 55 4.21E-8 T 09-03-2017 IPR009061 Putative DNA-binding domain L21SP3_RS05310 ea004baf64728d008b0ba2998c202020 63 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 12 55 8.7E-11 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 L21SP3_RS05310 ea004baf64728d008b0ba2998c202020 63 Pfam PF12728 Helix-turn-helix domain 7 55 2.0E-12 T 09-03-2017 L21SP3_RS09600 7b0b678453ed3eeee038568c8e706722 69 Pfam PF13240 zinc-ribbon domain 2 23 1.5E-9 T 09-03-2017 IPR026870 Zinc-ribbon domain L21SP3_RS02425 30ae8ac7665e45ca9e27c1c2d1ddbf6b 303 Gene3D G3DSA:2.160.10.10 179 287 1.3E-27 T 09-03-2017 L21SP3_RS02425 30ae8ac7665e45ca9e27c1c2d1ddbf6b 303 SUPERFAMILY SSF51161 108 285 8.73E-44 T 09-03-2017 IPR011004 Trimeric LpxA-like L21SP3_RS02425 30ae8ac7665e45ca9e27c1c2d1ddbf6b 303 Gene3D G3DSA:1.10.3130.10 28 178 1.1E-36 T 09-03-2017 L21SP3_RS02425 30ae8ac7665e45ca9e27c1c2d1ddbf6b 303 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 188 223 1.0E-4 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS02425 30ae8ac7665e45ca9e27c1c2d1ddbf6b 303 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 242 275 2.6E-7 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS09730 6b5533689807edcf7721cecb2571e87b 472 ProSitePatterns PS00523 Sulfatases signature 1. 85 97 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS09730 6b5533689807edcf7721cecb2571e87b 472 SUPERFAMILY SSF53649 38 462 1.57E-99 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09730 6b5533689807edcf7721cecb2571e87b 472 Pfam PF00884 Sulfatase 40 361 9.2E-55 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS09730 6b5533689807edcf7721cecb2571e87b 472 Gene3D G3DSA:3.40.720.10 38 382 1.2E-88 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS04190 ba8e5e3df97dcb076e5d8db539736a93 179 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 158 179 1.9E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS04190 ba8e5e3df97dcb076e5d8db539736a93 179 Pfam PF07589 PEP-CTERM motif 158 178 2.2E-7 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS00855 661245d23ee1dc9ce33c7e2c99c0b695 98 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 15 84 5.6E-21 T 09-03-2017 IPR003746 Protein of unknown function DUF167 L21SP3_RS00855 661245d23ee1dc9ce33c7e2c99c0b695 98 SUPERFAMILY SSF69786 8 88 4.84E-23 T 09-03-2017 IPR003746 Protein of unknown function DUF167 L21SP3_RS00855 661245d23ee1dc9ce33c7e2c99c0b695 98 Gene3D G3DSA:3.30.1200.10 8 91 5.9E-24 T 09-03-2017 IPR003746 Protein of unknown function DUF167 L21SP3_RS00855 661245d23ee1dc9ce33c7e2c99c0b695 98 SMART SM01152 10 86 3.5E-25 T 09-03-2017 IPR003746 Protein of unknown function DUF167 L21SP3_RS00855 661245d23ee1dc9ce33c7e2c99c0b695 98 Hamap MF_00634 UPF0235 protein YggU [yggU]. 9 98 17.043 T 09-03-2017 IPR003746 Protein of unknown function DUF167 L21SP3_RS11525 6308354705c6565b283d3cc25f5aab91 444 SUPERFAMILY SSF103263 240 437 1.57E-90 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 L21SP3_RS11525 6308354705c6565b283d3cc25f5aab91 444 SUPERFAMILY SSF103263 7 186 1.57E-90 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 L21SP3_RS11525 6308354705c6565b283d3cc25f5aab91 444 ProSitePatterns PS00788 Chorismate synthase signature 2. 138 154 - T 09-03-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 L21SP3_RS11525 6308354705c6565b283d3cc25f5aab91 444 Gene3D G3DSA:3.60.150.10 257 437 1.2E-103 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 L21SP3_RS11525 6308354705c6565b283d3cc25f5aab91 444 Gene3D G3DSA:3.60.150.10 10 195 1.2E-103 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 L21SP3_RS11525 6308354705c6565b283d3cc25f5aab91 444 Pfam PF01264 Chorismate synthase 10 429 1.8E-93 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 L21SP3_RS08835 9a907451418edb7747c8ace8c861b522 624 Gene3D G3DSA:2.60.120.200 433 621 2.1E-14 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS08835 9a907451418edb7747c8ace8c861b522 624 SUPERFAMILY SSF49899 447 618 4.29E-17 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS08835 9a907451418edb7747c8ace8c861b522 624 SMART SM00282 468 609 1.2E-4 T 09-03-2017 IPR001791 Laminin G domain L21SP3_RS08835 9a907451418edb7747c8ace8c861b522 624 SUPERFAMILY SSF56300 27 337 6.07E-20 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS08835 9a907451418edb7747c8ace8c861b522 624 Pfam PF00149 Calcineurin-like phosphoesterase 30 302 1.4E-6 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 L21SP3_RS08835 9a907451418edb7747c8ace8c861b522 624 Pfam PF02210 Laminin G domain 487 606 1.2E-7 T 09-03-2017 IPR001791 Laminin G domain L21SP3_RS08835 9a907451418edb7747c8ace8c861b522 624 Gene3D G3DSA:3.60.21.10 25 159 3.0E-23 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS08835 9a907451418edb7747c8ace8c861b522 624 Gene3D G3DSA:3.60.21.10 192 341 3.0E-23 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS05115 de490f782538e81a011462ec7f1a086a 240 SUPERFAMILY SSF49344 24 239 6.28E-24 T 09-03-2017 L21SP3_RS05115 de490f782538e81a011462ec7f1a086a 240 Pfam PF16011 Carbohydrate-binding family 9 47 239 4.2E-42 T 09-03-2017 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 L21SP3_RS05115 de490f782538e81a011462ec7f1a086a 240 Gene3D G3DSA:2.60.40.1190 25 239 1.8E-22 T 09-03-2017 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 L21SP3_RS08185 cb2b7c02c845c6b8ca71df0d60b0cd48 862 Pfam PF17137 Domain of unknown function (DUF5110) 725 799 1.3E-13 T 09-03-2017 IPR033403 Domain of unknown function DUF5110 L21SP3_RS08185 cb2b7c02c845c6b8ca71df0d60b0cd48 862 SUPERFAMILY SSF51445 322 622 2.8E-40 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS08185 cb2b7c02c845c6b8ca71df0d60b0cd48 862 SUPERFAMILY SSF51011 624 704 1.8E-13 T 09-03-2017 L21SP3_RS08185 cb2b7c02c845c6b8ca71df0d60b0cd48 862 Pfam PF01055 Glycosyl hydrolases family 31 317 417 1.5E-16 T 09-03-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 L21SP3_RS08185 cb2b7c02c845c6b8ca71df0d60b0cd48 862 Pfam PF01055 Glycosyl hydrolases family 31 432 709 1.4E-59 T 09-03-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 L21SP3_RS08185 cb2b7c02c845c6b8ca71df0d60b0cd48 862 SUPERFAMILY SSF50370 140 256 1.08E-7 T 09-03-2017 IPR000772 Ricin B, lectin domain L21SP3_RS08185 cb2b7c02c845c6b8ca71df0d60b0cd48 862 Gene3D G3DSA:2.80.10.50 140 254 5.2E-14 T 09-03-2017 L21SP3_RS04450 c9aa4ea8b5435490fcc04c8eb9c0a277 58 Pfam PF13366 PD-(D/E)XK nuclease superfamily 1 55 1.8E-17 T 09-03-2017 IPR026350 GxxExxY protein L21SP3_RS04450 c9aa4ea8b5435490fcc04c8eb9c0a277 58 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 1 57 1.2E-18 T 09-03-2017 IPR026350 GxxExxY protein L21SP3_RS10335 fe5fbd6fa95219f4560963305d0a706d 399 SUPERFAMILY SSF53822 61 294 2.55E-24 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS10335 fe5fbd6fa95219f4560963305d0a706d 399 SMART SM00342 301 384 1.4E-18 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS10335 fe5fbd6fa95219f4560963305d0a706d 399 SUPERFAMILY SSF46689 338 388 1.79E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS10335 fe5fbd6fa95219f4560963305d0a706d 399 Pfam PF12833 Helix-turn-helix domain 308 385 5.5E-19 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS10335 fe5fbd6fa95219f4560963305d0a706d 399 Gene3D G3DSA:1.10.10.60 338 388 6.7E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS10335 fe5fbd6fa95219f4560963305d0a706d 399 Pfam PF13377 Periplasmic binding protein-like domain 114 277 2.7E-27 T 09-03-2017 L21SP3_RS10335 fe5fbd6fa95219f4560963305d0a706d 399 Gene3D G3DSA:3.40.50.2300 100 277 1.0E-24 T 09-03-2017 L21SP3_RS10335 fe5fbd6fa95219f4560963305d0a706d 399 Gene3D G3DSA:1.10.10.60 284 337 5.7E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS05355 8dc358b7f3e66b2537008d0ef4a96a8e 445 Pfam PF16193 AAA C-terminal domain 191 271 6.0E-27 T 09-03-2017 IPR032423 AAA ATPase, C-terminal domain L21SP3_RS05355 8dc358b7f3e66b2537008d0ef4a96a8e 445 Gene3D G3DSA:1.10.3710.10 353 441 1.4E-20 T 09-03-2017 L21SP3_RS05355 8dc358b7f3e66b2537008d0ef4a96a8e 445 Gene3D G3DSA:1.20.272.10 253 351 9.3E-42 T 09-03-2017 L21SP3_RS05355 8dc358b7f3e66b2537008d0ef4a96a8e 445 Gene3D G3DSA:3.40.50.300 16 158 3.0E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05355 8dc358b7f3e66b2537008d0ef4a96a8e 445 SUPERFAMILY SSF48019 257 438 1.93E-65 T 09-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 L21SP3_RS05355 8dc358b7f3e66b2537008d0ef4a96a8e 445 Pfam PF12002 MgsA AAA+ ATPase C terminal 272 435 2.5E-62 T 09-03-2017 IPR021886 MgsA AAA+ ATPase C-terminal L21SP3_RS05355 8dc358b7f3e66b2537008d0ef4a96a8e 445 SMART SM00382 52 170 2.4E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS05355 8dc358b7f3e66b2537008d0ef4a96a8e 445 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 56 158 2.1E-16 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP3_RS05355 8dc358b7f3e66b2537008d0ef4a96a8e 445 SUPERFAMILY SSF52540 18 227 2.21E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05355 8dc358b7f3e66b2537008d0ef4a96a8e 445 Gene3D G3DSA:1.10.8.60 159 243 2.5E-12 T 09-03-2017 L21SP3_RS09110 d8ef9bd6778515beb1d4a1b41d0ec617 345 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 146 179 5.6E-4 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS09110 d8ef9bd6778515beb1d4a1b41d0ec617 345 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 144 1.4E-6 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS09110 d8ef9bd6778515beb1d4a1b41d0ec617 345 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 222 257 2.7E-6 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS09110 d8ef9bd6778515beb1d4a1b41d0ec617 345 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 24 87 1.7E-18 T 09-03-2017 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 L21SP3_RS09110 d8ef9bd6778515beb1d4a1b41d0ec617 345 SUPERFAMILY SSF51161 33 311 1.22E-70 T 09-03-2017 IPR011004 Trimeric LpxA-like L21SP3_RS09110 d8ef9bd6778515beb1d4a1b41d0ec617 345 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 8 328 5.2E-95 T 09-03-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 L21SP3_RS09110 d8ef9bd6778515beb1d4a1b41d0ec617 345 Gene3D G3DSA:2.160.10.10 208 306 1.6E-24 T 09-03-2017 L21SP3_RS09110 d8ef9bd6778515beb1d4a1b41d0ec617 345 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 5 325 30.959 T 09-03-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 L21SP3_RS09110 d8ef9bd6778515beb1d4a1b41d0ec617 345 Gene3D G3DSA:2.160.10.10 107 207 1.6E-23 T 09-03-2017 L21SP3_RS09110 d8ef9bd6778515beb1d4a1b41d0ec617 345 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 267 295 - T 09-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 L21SP3_RS10535 107da691556ca6c4ab91eaef1ccb1292 327 Gene3D G3DSA:3.50.50.60 242 306 3.6E-6 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10535 107da691556ca6c4ab91eaef1ccb1292 327 Gene3D G3DSA:3.50.50.60 113 163 3.6E-6 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10535 107da691556ca6c4ab91eaef1ccb1292 327 Gene3D G3DSA:3.50.50.60 20 45 3.6E-6 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS10535 107da691556ca6c4ab91eaef1ccb1292 327 Pfam PF12831 FAD dependent oxidoreductase 19 314 1.8E-68 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS08960 a5b791b94a5ab6142ee20364718e8128 1059 Pfam PF12705 PD-(D/E)XK nuclease superfamily 702 1028 2.6E-26 T 09-03-2017 L21SP3_RS08960 a5b791b94a5ab6142ee20364718e8128 1059 Gene3D G3DSA:3.40.50.300 177 235 4.6E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08960 a5b791b94a5ab6142ee20364718e8128 1059 Gene3D G3DSA:3.40.50.300 5 88 4.6E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08960 a5b791b94a5ab6142ee20364718e8128 1059 Gene3D G3DSA:3.40.50.300 525 613 7.8E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08960 a5b791b94a5ab6142ee20364718e8128 1059 Gene3D G3DSA:3.40.50.300 286 378 7.8E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08960 a5b791b94a5ab6142ee20364718e8128 1059 SUPERFAMILY SSF52540 3 612 2.33E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00550 993a6f91cfac661c9b8acd71531874a9 587 Gene3D G3DSA:3.10.410.10 472 562 2.3E-30 T 09-03-2017 L21SP3_RS00550 993a6f91cfac661c9b8acd71531874a9 587 Pfam PF01268 Formate--tetrahydrofolate ligase 9 587 5.2E-229 T 09-03-2017 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 L21SP3_RS00550 993a6f91cfac661c9b8acd71531874a9 587 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 112 122 - T 09-03-2017 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 L21SP3_RS00550 993a6f91cfac661c9b8acd71531874a9 587 Gene3D G3DSA:3.40.50.300 270 470 4.4E-130 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00550 993a6f91cfac661c9b8acd71531874a9 587 Gene3D G3DSA:3.40.50.300 21 137 4.4E-130 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00550 993a6f91cfac661c9b8acd71531874a9 587 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 350 361 - T 09-03-2017 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 L21SP3_RS00550 993a6f91cfac661c9b8acd71531874a9 587 SUPERFAMILY SSF52540 16 584 2.26E-203 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00550 993a6f91cfac661c9b8acd71531874a9 587 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 7 587 39.372 T 09-03-2017 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 L21SP3_RS00550 993a6f91cfac661c9b8acd71531874a9 587 Gene3D G3DSA:3.30.1510.10 138 268 2.8E-40 T 09-03-2017 L21SP3_RS01675 bd9c937adb50a03ed1600025cabd16a2 729 Gene3D G3DSA:2.160.20.10 199 548 7.4E-37 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS01675 bd9c937adb50a03ed1600025cabd16a2 729 SUPERFAMILY SSF51126 636 666 1.26E-35 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS01675 bd9c937adb50a03ed1600025cabd16a2 729 SUPERFAMILY SSF51126 592 608 1.26E-35 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS01675 bd9c937adb50a03ed1600025cabd16a2 729 SUPERFAMILY SSF51126 198 555 1.26E-35 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS01675 bd9c937adb50a03ed1600025cabd16a2 729 ProSitePatterns PS00018 EF-hand calcium-binding domain. 694 706 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS01675 bd9c937adb50a03ed1600025cabd16a2 729 Pfam PF13229 Right handed beta helix region 389 538 3.1E-12 T 09-03-2017 L21SP3_RS08305 9fae6aceb99b85476ab21284bcd51b09 285 SUPERFAMILY SSF56436 145 263 5.65E-33 T 09-03-2017 IPR016187 C-type lectin fold L21SP3_RS08305 9fae6aceb99b85476ab21284bcd51b09 285 SUPERFAMILY SSF56436 35 112 5.65E-33 T 09-03-2017 IPR016187 C-type lectin fold L21SP3_RS08305 9fae6aceb99b85476ab21284bcd51b09 285 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 264 285 0.0019 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS08305 9fae6aceb99b85476ab21284bcd51b09 285 Pfam PF03781 Sulfatase-modifying factor enzyme 1 52 262 8.9E-19 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS08305 9fae6aceb99b85476ab21284bcd51b09 285 Gene3D G3DSA:3.90.1580.10 50 263 2.5E-28 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS02825 b9f502827388184545b3f7d4a4be54af 461 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 10 418 3.3E-117 T 09-03-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit L21SP3_RS02825 b9f502827388184545b3f7d4a4be54af 461 PIRSF PIRSF006066 3 429 1.1E-156 T 09-03-2017 IPR004681 TRAP transporter permease protein GO:0016021 L21SP3_RS02825 b9f502827388184545b3f7d4a4be54af 461 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 20 424 1.1E-131 T 09-03-2017 IPR004681 TRAP transporter permease protein GO:0016021 L21SP3_RS07420 0abab134d868568eed963a9fa08d3841 329 Gene3D G3DSA:1.10.3720.10 97 318 2.2E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS07420 0abab134d868568eed963a9fa08d3841 329 SUPERFAMILY SSF161098 97 309 4.06E-15 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS07420 0abab134d868568eed963a9fa08d3841 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 327 6.7E-36 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS04575 a0519f31576ae2eca2817e255cee54fb 378 Gene3D G3DSA:2.120.10.80 71 373 2.5E-33 T 09-03-2017 IPR015915 Kelch-type beta propeller GO:0005515 L21SP3_RS04575 a0519f31576ae2eca2817e255cee54fb 378 Pfam PF01344 Kelch motif 240 274 1.2E-5 T 09-03-2017 IPR006652 Kelch repeat type 1 GO:0005515 L21SP3_RS04575 a0519f31576ae2eca2817e255cee54fb 378 Pfam PF01344 Kelch motif 169 206 1.7E-4 T 09-03-2017 IPR006652 Kelch repeat type 1 GO:0005515 L21SP3_RS04575 a0519f31576ae2eca2817e255cee54fb 378 SUPERFAMILY SSF117281 72 373 1.05E-34 T 09-03-2017 L21SP3_RS01160 9f1bf0d71c63b96d383f53cdd8673d05 656 Gene3D G3DSA:2.60.120.380 493 610 6.7E-4 T 09-03-2017 L21SP3_RS01160 9f1bf0d71c63b96d383f53cdd8673d05 656 Gene3D G3DSA:2.60.120.380 26 105 8.1E-5 T 09-03-2017 L21SP3_RS09575 383e8f0c445056221016043a7de6f9ef 55 Pfam PF07432 Histone H1-like protein Hc1 4 36 5.9E-6 T 09-03-2017 IPR010886 Histone H1-like Hc1 GO:0003677 L21SP3_RS00995 fccb33c5fc419d9e6311b6da51dbb2d5 338 Gene3D G3DSA:3.40.718.10 1 329 1.9E-120 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 L21SP3_RS00995 fccb33c5fc419d9e6311b6da51dbb2d5 338 Pfam PF02504 Fatty acid synthesis protein 1 322 6.3E-104 T 09-03-2017 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 L21SP3_RS00995 fccb33c5fc419d9e6311b6da51dbb2d5 338 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 338 125.17 T 09-03-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 L21SP3_RS00995 fccb33c5fc419d9e6311b6da51dbb2d5 338 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 331 6.3E-101 T 09-03-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 L21SP3_RS00995 fccb33c5fc419d9e6311b6da51dbb2d5 338 SUPERFAMILY SSF53659 1 329 9.05E-91 T 09-03-2017 L21SP3_RS00995 fccb33c5fc419d9e6311b6da51dbb2d5 338 PIRSF PIRSF002465 1 334 8.8E-114 T 09-03-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 L21SP3_RS00240 aa1790208d0f38863183bbee46b8f283 609 SUPERFAMILY SSF82282 1 373 2.49E-88 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 L21SP3_RS00240 aa1790208d0f38863183bbee46b8f283 609 Pfam PF02219 Methylenetetrahydrofolate reductase 325 586 1.3E-33 T 09-03-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 L21SP3_RS00240 aa1790208d0f38863183bbee46b8f283 609 Pfam PF02574 Homocysteine S-methyltransferase 12 286 1.3E-60 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 L21SP3_RS00240 aa1790208d0f38863183bbee46b8f283 609 Gene3D G3DSA:3.20.20.330 1 331 6.7E-90 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 L21SP3_RS00240 aa1790208d0f38863183bbee46b8f283 609 Gene3D G3DSA:3.20.20.220 332 593 2.2E-59 T 09-03-2017 IPR029041 FAD-linked oxidoreductase-like L21SP3_RS00240 aa1790208d0f38863183bbee46b8f283 609 SUPERFAMILY SSF51730 323 607 1.69E-67 T 09-03-2017 IPR029041 FAD-linked oxidoreductase-like L21SP3_RS04770 970acb8efd0d39af86a31fe744719acf 415 SUPERFAMILY SSF53756 2 402 1.29E-46 T 09-03-2017 L21SP3_RS04770 970acb8efd0d39af86a31fe744719acf 415 Pfam PF13579 Glycosyl transferase 4-like domain 22 199 9.8E-16 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 L21SP3_RS04770 970acb8efd0d39af86a31fe744719acf 415 Pfam PF00534 Glycosyl transferases group 1 218 373 1.0E-17 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS04770 970acb8efd0d39af86a31fe744719acf 415 Gene3D G3DSA:3.40.50.2000 192 381 8.5E-10 T 09-03-2017 L21SP3_RS11300 ffb4092c77782b669a5adaa3ecd4081c 349 SUPERFAMILY SSF111337 1 348 1.05E-125 T 09-03-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 L21SP3_RS11300 ffb4092c77782b669a5adaa3ecd4081c 349 Gene3D G3DSA:3.40.1780.10 1 62 7.0E-98 T 09-03-2017 L21SP3_RS11300 ffb4092c77782b669a5adaa3ecd4081c 349 Gene3D G3DSA:3.40.1780.10 187 348 7.0E-98 T 09-03-2017 L21SP3_RS11300 ffb4092c77782b669a5adaa3ecd4081c 349 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 348 6.8E-123 T 09-03-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 L21SP3_RS11300 ffb4092c77782b669a5adaa3ecd4081c 349 Pfam PF02547 Queuosine biosynthesis protein 4 348 2.5E-128 T 09-03-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 L21SP3_RS11300 ffb4092c77782b669a5adaa3ecd4081c 349 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 349 44.058 T 09-03-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 L21SP3_RS11300 ffb4092c77782b669a5adaa3ecd4081c 349 Gene3D G3DSA:2.40.10.240 66 146 2.3E-10 T 09-03-2017 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 Gene3D G3DSA:3.40.1060.10 163 269 3.7E-28 T 09-03-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 ProSitePatterns PS00450 Aconitase family signature 1. 297 313 - T 09-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 6 420 2.0E-172 T 09-03-2017 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 Pfam PF00330 Aconitase family (aconitate hydratase) 28 414 1.7E-93 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 SUPERFAMILY SSF53732 3 421 1.16E-134 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 Gene3D G3DSA:3.30.499.10 3 161 3.0E-35 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 PRINTS PR00415 Aconitase family signature 301 312 1.4E-22 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 PRINTS PR00415 Aconitase family signature 192 205 1.4E-22 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 PRINTS PR00415 Aconitase family signature 206 219 1.4E-22 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 PRINTS PR00415 Aconitase family signature 116 129 1.4E-22 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 PRINTS PR00415 Aconitase family signature 130 145 1.4E-22 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 PRINTS PR00415 Aconitase family signature 355 368 1.4E-22 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 Gene3D G3DSA:3.30.499.10 278 421 3.1E-52 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 5 420 6.5E-151 T 09-03-2017 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 L21SP3_RS02440 2e9e213a4ed7b4348e9fb5820f64eaab 423 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 5 422 47.041 T 09-03-2017 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 Gene3D G3DSA:3.30.70.20 198 257 3.4E-5 T 09-03-2017 L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 Gene3D G3DSA:3.30.70.20 342 378 6.7E-9 T 09-03-2017 L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 539 550 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 Gene3D G3DSA:1.10.1060.10 258 341 3.0E-5 T 09-03-2017 L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 SUPERFAMILY SSF54862 72 121 2.02E-11 T 09-03-2017 L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 SUPERFAMILY SSF54862 194 265 2.02E-11 T 09-03-2017 L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 Pfam PF12801 4Fe-4S binding domain 63 104 2.9E-12 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 Pfam PF12801 4Fe-4S binding domain 178 219 7.3E-5 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 SUPERFAMILY SSF54862 331 459 4.19E-11 T 09-03-2017 L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 334 345 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 SUPERFAMILY SSF54862 526 559 1.81E-5 T 09-03-2017 L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 Gene3D G3DSA:1.10.1060.10 442 462 2.7E-5 T 09-03-2017 L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 Gene3D G3DSA:1.10.1060.10 516 552 2.7E-5 T 09-03-2017 L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 Pfam PF13187 4Fe-4S dicluster domain 333 391 8.8E-7 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 Gene3D G3DSA:3.30.70.20 379 441 3.3E-4 T 09-03-2017 L21SP3_RS01755 bfe16068cf4b29b6c79ba308c68b34e8 576 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 253 264 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS05120 8ea419a2811a448421f8013379af2998 297 SMART SM00342 208 291 2.8E-25 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS05120 8ea419a2811a448421f8013379af2998 297 SUPERFAMILY SSF46689 245 294 2.51E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS05120 8ea419a2811a448421f8013379af2998 297 SUPERFAMILY SSF51215 39 172 1.31E-21 T 09-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP3_RS05120 8ea419a2811a448421f8013379af2998 297 SUPERFAMILY SSF46689 193 242 4.48E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS05120 8ea419a2811a448421f8013379af2998 297 Gene3D G3DSA:1.10.10.60 191 244 2.8E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS05120 8ea419a2811a448421f8013379af2998 297 Pfam PF12833 Helix-turn-helix domain 215 292 1.2E-19 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS05120 8ea419a2811a448421f8013379af2998 297 Gene3D G3DSA:1.10.10.60 245 293 1.3E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS05120 8ea419a2811a448421f8013379af2998 297 Pfam PF02311 AraC-like ligand binding domain 45 133 2.5E-9 T 09-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP3_RS05120 8ea419a2811a448421f8013379af2998 297 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 245 287 - T 09-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 L21SP3_RS05120 8ea419a2811a448421f8013379af2998 297 Gene3D G3DSA:2.60.120.280 37 175 9.9E-19 T 09-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP3_RS00040 b3dbc34854de533461c18d5afbb0e999 208 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 187 207 5.0E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS00040 b3dbc34854de533461c18d5afbb0e999 208 Pfam PF07589 PEP-CTERM motif 187 207 1.2E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 Gene3D G3DSA:2.40.30.10 94 197 1.6E-23 T 09-03-2017 L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 Pfam PF00175 Oxidoreductase NAD-binding domain 209 309 5.8E-18 T 09-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 SUPERFAMILY SSF54292 6 89 5.39E-15 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 SUPERFAMILY SSF63380 93 200 3.4E-24 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 Pfam PF00970 Oxidoreductase FAD-binding domain 105 198 2.0E-18 T 09-03-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 PRINTS PR00410 Phenol hydroxylase reductase family signature 127 139 1.1E-15 T 09-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 PRINTS PR00410 Phenol hydroxylase reductase family signature 193 202 1.1E-15 T 09-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 PRINTS PR00410 Phenol hydroxylase reductase family signature 233 242 1.1E-15 T 09-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 PRINTS PR00410 Phenol hydroxylase reductase family signature 208 227 1.1E-15 T 09-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 PRINTS PR00410 Phenol hydroxylase reductase family signature 298 306 1.1E-15 T 09-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 81 2.6E-6 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 SUPERFAMILY SSF52343 202 331 3.27E-34 T 09-03-2017 L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 Gene3D G3DSA:3.40.50.80 202 331 2.4E-35 T 09-03-2017 L21SP3_RS08810 100e95db649cafccd0a37125c42d8eec 331 Gene3D G3DSA:3.10.20.30 6 88 6.2E-15 T 09-03-2017 IPR012675 Beta-grasp domain L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 Gene3D G3DSA:1.10.1780.10 1 147 2.2E-36 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 Pfam PF07724 AAA domain (Cdc48 subfamily) 599 763 5.8E-55 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 SUPERFAMILY SSF52540 158 548 2.27E-96 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 SUPERFAMILY SSF52540 549 855 1.47E-81 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 332 1.5E-12 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 770 849 5.9E-28 T 09-03-2017 IPR019489 Clp ATPase, C-terminal L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 SUPERFAMILY SSF81923 4 154 1.28E-32 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 Gene3D G3DSA:1.10.8.60 342 427 1.1E-35 T 09-03-2017 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 Gene3D G3DSA:3.40.50.300 158 340 5.9E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 856 0.0 T 09-03-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 293 305 - T 09-03-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 604 622 1.3E-40 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 667 1.3E-40 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 678 696 1.3E-40 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 711 725 1.3E-40 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 SMART SM00382 197 341 4.3E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 SMART SM00382 600 756 1.7E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 144 7.8E-10 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 67 1.5E-10 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 Gene3D G3DSA:1.10.8.60 782 860 4.7E-32 T 09-03-2017 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 SMART SM01086 770 857 1.8E-35 T 09-03-2017 IPR019489 Clp ATPase, C-terminal L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 634 652 - T 09-03-2017 IPR028299 ClpA/B, conserved site 2 L21SP3_RS06960 6be387eea4dbe8abcd53dd4fa020ce4d 866 Gene3D G3DSA:3.40.50.300 558 781 9.2E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09765 e955b4b2feb19a9d4d3d27f7de05da9f 648 ProSitePatterns PS00018 EF-hand calcium-binding domain. 629 641 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS09765 e955b4b2feb19a9d4d3d27f7de05da9f 648 Gene3D G3DSA:1.10.1330.10 594 647 3.4E-5 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS04625 ea303b7b2e34bf123e314ebd23582b16 1270 Gene3D G3DSA:2.80.10.50 689 779 3.6E-6 T 09-03-2017 L21SP3_RS04625 ea303b7b2e34bf123e314ebd23582b16 1270 SUPERFAMILY SSF49265 823 908 2.76E-7 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 L21SP3_RS04625 ea303b7b2e34bf123e314ebd23582b16 1270 Gene3D G3DSA:2.60.40.10 826 908 7.5E-10 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS04625 ea303b7b2e34bf123e314ebd23582b16 1270 ProSitePatterns PS00018 EF-hand calcium-binding domain. 1230 1242 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS05245 64526d745d10891198fc648a3c4bfc35 232 SUPERFAMILY SSF54523 6 104 1.18E-14 T 09-03-2017 L21SP3_RS05245 64526d745d10891198fc648a3c4bfc35 232 PRINTS PR00813 Bacterial general secretion pathway protein G signature 41 59 6.4E-9 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS05245 64526d745d10891198fc648a3c4bfc35 232 PRINTS PR00813 Bacterial general secretion pathway protein G signature 5 30 6.4E-9 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS05245 64526d745d10891198fc648a3c4bfc35 232 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS05245 64526d745d10891198fc648a3c4bfc35 232 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 25 2.0E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS05245 64526d745d10891198fc648a3c4bfc35 232 Gene3D G3DSA:3.30.700.10 6 60 4.3E-5 T 09-03-2017 L21SP3_RS05245 64526d745d10891198fc648a3c4bfc35 232 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 2 23 6.2E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS01180 6e063db47d56d1047353373e0bf6cdfe 495 Gene3D G3DSA:3.20.20.80 74 358 4.7E-25 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS01180 6e063db47d56d1047353373e0bf6cdfe 495 SUPERFAMILY SSF51445 40 219 5.21E-46 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS01180 6e063db47d56d1047353373e0bf6cdfe 495 SUPERFAMILY SSF51445 259 389 5.21E-46 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS10155 2602be63f6a3b2933e1d099b4a7c6703 367 SMART SM00740 47 114 2.4E-12 T 09-03-2017 IPR005543 PASTA domain L21SP3_RS10155 2602be63f6a3b2933e1d099b4a7c6703 367 Gene3D G3DSA:3.90.1580.10 152 366 1.2E-29 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS10155 2602be63f6a3b2933e1d099b4a7c6703 367 Pfam PF03781 Sulfatase-modifying factor enzyme 1 152 364 4.3E-22 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS10155 2602be63f6a3b2933e1d099b4a7c6703 367 ProSitePatterns PS00018 EF-hand calcium-binding domain. 26 38 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS10155 2602be63f6a3b2933e1d099b4a7c6703 367 Pfam PF03793 PASTA domain 51 113 3.8E-12 T 09-03-2017 IPR005543 PASTA domain L21SP3_RS10155 2602be63f6a3b2933e1d099b4a7c6703 367 SUPERFAMILY SSF56436 125 366 4.71E-31 T 09-03-2017 IPR016187 C-type lectin fold L21SP3_RS08265 4354804aa15d04c3931f07c6a1df7a68 584 Gene3D G3DSA:3.40.50.1390 10 147 2.5E-33 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 L21SP3_RS08265 4354804aa15d04c3931f07c6a1df7a68 584 Pfam PF13408 Recombinase zinc beta ribbon domain 298 350 1.3E-8 T 09-03-2017 IPR025827 Recombinase zinc beta ribbon domain L21SP3_RS08265 4354804aa15d04c3931f07c6a1df7a68 584 Pfam PF07508 Recombinase 187 283 1.1E-12 T 09-03-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 L21SP3_RS08265 4354804aa15d04c3931f07c6a1df7a68 584 Pfam PF00239 Resolvase, N terminal domain 12 164 2.8E-38 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 L21SP3_RS08265 4354804aa15d04c3931f07c6a1df7a68 584 SMART SM00857 11 164 8.0E-61 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 L21SP3_RS08265 4354804aa15d04c3931f07c6a1df7a68 584 SUPERFAMILY SSF53041 10 164 1.57E-39 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 L21SP3_RS04180 647c9def53ef973bfedb751d85ac16f9 471 Gene3D G3DSA:2.10.109.10 393 447 1.1E-36 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain L21SP3_RS04180 647c9def53ef973bfedb751d85ac16f9 471 Gene3D G3DSA:2.10.109.10 25 46 1.1E-36 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain L21SP3_RS04180 647c9def53ef973bfedb751d85ac16f9 471 Gene3D G3DSA:2.10.109.10 96 140 1.1E-36 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain L21SP3_RS04180 647c9def53ef973bfedb751d85ac16f9 471 Pfam PF00717 Peptidase S24-like 97 153 2.2E-8 T 09-03-2017 IPR019759 Peptidase S24/S26A/S26B L21SP3_RS04180 647c9def53ef973bfedb751d85ac16f9 471 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 97 159 8.5E-15 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 L21SP3_RS04180 647c9def53ef973bfedb751d85ac16f9 471 ProSitePatterns PS00760 Signal peptidases I lysine active site. 132 144 - T 09-03-2017 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 L21SP3_RS04180 647c9def53ef973bfedb751d85ac16f9 471 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 130 142 5.6E-17 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 L21SP3_RS04180 647c9def53ef973bfedb751d85ac16f9 471 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 393 412 5.6E-17 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 L21SP3_RS04180 647c9def53ef973bfedb751d85ac16f9 471 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 29 45 5.6E-17 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 L21SP3_RS04180 647c9def53ef973bfedb751d85ac16f9 471 SUPERFAMILY SSF51306 384 446 1.94E-9 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C L21SP3_RS04180 647c9def53ef973bfedb751d85ac16f9 471 SUPERFAMILY SSF51306 96 166 2.2E-22 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C L21SP3_RS04180 647c9def53ef973bfedb751d85ac16f9 471 SUPERFAMILY SSF51306 27 46 2.2E-22 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C L21SP3_RS04405 9cbadbdefa2dd02ef2dac9a924afc7e1 182 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 24 172 1.7E-48 T 09-03-2017 IPR026353 Hypoxanthine-DNA glycosylase L21SP3_RS04405 9cbadbdefa2dd02ef2dac9a924afc7e1 182 SMART SM00986 21 176 5.2E-7 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 L21SP3_RS04405 9cbadbdefa2dd02ef2dac9a924afc7e1 182 Gene3D G3DSA:3.40.470.10 24 180 6.5E-33 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 L21SP3_RS04405 9cbadbdefa2dd02ef2dac9a924afc7e1 182 Pfam PF03167 Uracil DNA glycosylase superfamily 25 172 3.7E-9 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 L21SP3_RS04405 9cbadbdefa2dd02ef2dac9a924afc7e1 182 SMART SM00987 21 176 5.2E-7 T 09-03-2017 L21SP3_RS04405 9cbadbdefa2dd02ef2dac9a924afc7e1 182 SUPERFAMILY SSF52141 25 177 6.93E-33 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 L21SP3_RS00935 b27b04fa5fab5318194ff3d1a50913ad 341 SUPERFAMILY SSF53448 15 229 7.31E-50 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS00935 b27b04fa5fab5318194ff3d1a50913ad 341 Pfam PF00535 Glycosyl transferase family 2 17 182 6.5E-30 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 L21SP3_RS00935 b27b04fa5fab5318194ff3d1a50913ad 341 Gene3D G3DSA:3.90.550.10 15 231 6.9E-53 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS02655 34a39fcf689d34d3412d8ec6379a3db0 761 Gene3D G3DSA:1.25.10.10 643 750 7.5E-5 T 09-03-2017 IPR011989 Armadillo-like helical L21SP3_RS02655 34a39fcf689d34d3412d8ec6379a3db0 761 Gene3D G3DSA:1.25.40.10 325 425 5.4E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS02655 34a39fcf689d34d3412d8ec6379a3db0 761 Gene3D G3DSA:1.25.40.10 148 262 5.4E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS02655 34a39fcf689d34d3412d8ec6379a3db0 761 SUPERFAMILY SSF48371 656 748 9.21E-6 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 L21SP3_RS02655 34a39fcf689d34d3412d8ec6379a3db0 761 SUPERFAMILY SSF48371 60 156 9.21E-6 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 L21SP3_RS02655 34a39fcf689d34d3412d8ec6379a3db0 761 SUPERFAMILY SSF48452 333 429 2.66E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS05495 051c0dd5119a432f7fa4a3ad5fb89c7f 345 Pfam PF00534 Glycosyl transferases group 1 162 315 1.3E-36 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS05495 051c0dd5119a432f7fa4a3ad5fb89c7f 345 Pfam PF13439 Glycosyltransferase Family 4 12 152 1.7E-16 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 L21SP3_RS05495 051c0dd5119a432f7fa4a3ad5fb89c7f 345 SUPERFAMILY SSF53756 8 342 7.85E-70 T 09-03-2017 L21SP3_RS05495 051c0dd5119a432f7fa4a3ad5fb89c7f 345 Gene3D G3DSA:3.40.50.2000 164 317 4.3E-30 T 09-03-2017 L21SP3_RS06655 fe71c7cc1b5c32be08f229231dce88e8 508 SUPERFAMILY SSF69318 51 384 8.11E-51 T 09-03-2017 L21SP3_RS06655 fe71c7cc1b5c32be08f229231dce88e8 508 Pfam PF07593 ASPIC and UnbV 412 478 7.1E-13 T 09-03-2017 IPR011519 ASPIC/UnbV L21SP3_RS06655 fe71c7cc1b5c32be08f229231dce88e8 508 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 193 261 1.6E-10 T 09-03-2017 L21SP3_RS06655 fe71c7cc1b5c32be08f229231dce88e8 508 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 335 381 1.8E-7 T 09-03-2017 L21SP3_RS06655 fe71c7cc1b5c32be08f229231dce88e8 508 Gene3D G3DSA:2.130.10.130 142 382 1.5E-21 T 09-03-2017 L21SP3_RS06655 fe71c7cc1b5c32be08f229231dce88e8 508 Gene3D G3DSA:2.130.10.130 52 141 4.2E-7 T 09-03-2017 L21SP3_RS08820 a91d3653db4a727ffb6034877d531287 348 SUPERFAMILY SSF52949 1 148 1.48E-46 T 09-03-2017 L21SP3_RS08820 a91d3653db4a727ffb6034877d531287 348 SMART SM00506 1 132 4.3E-22 T 09-03-2017 IPR002589 Macro domain L21SP3_RS08820 a91d3653db4a727ffb6034877d531287 348 Pfam PF01661 Macro domain 18 131 1.1E-22 T 09-03-2017 IPR002589 Macro domain L21SP3_RS08820 a91d3653db4a727ffb6034877d531287 348 Gene3D G3DSA:3.40.220.10 2 135 3.5E-12 T 09-03-2017 L21SP3_RS05530 618065bad4dc16be4dbd8568d813d097 287 Gene3D G3DSA:3.40.50.150 5 96 1.9E-14 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS05530 618065bad4dc16be4dbd8568d813d097 287 Pfam PF01555 DNA methylase 6 98 7.0E-14 T 09-03-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 L21SP3_RS05530 618065bad4dc16be4dbd8568d813d097 287 Pfam PF01555 DNA methylase 116 276 1.1E-8 T 09-03-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 L21SP3_RS05530 618065bad4dc16be4dbd8568d813d097 287 Gene3D G3DSA:3.40.50.150 97 280 5.3E-16 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS05530 618065bad4dc16be4dbd8568d813d097 287 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 118 124 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 L21SP3_RS05530 618065bad4dc16be4dbd8568d813d097 287 SUPERFAMILY SSF53335 54 172 1.84E-19 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS03820 38d6da5013bfb9fa36702b21dd9dbca5 326 Gene3D G3DSA:3.40.50.300 4 258 5.2E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03820 38d6da5013bfb9fa36702b21dd9dbca5 326 SUPERFAMILY SSF52540 5 255 9.25E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03820 38d6da5013bfb9fa36702b21dd9dbca5 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 296 1.0E-18 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 L21SP3_RS03820 38d6da5013bfb9fa36702b21dd9dbca5 326 SMART SM00382 34 234 4.2E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS03820 38d6da5013bfb9fa36702b21dd9dbca5 326 Pfam PF00005 ABC transporter 27 184 1.5E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS03820 38d6da5013bfb9fa36702b21dd9dbca5 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 322 5.3E-25 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 L21SP3_RS03820 38d6da5013bfb9fa36702b21dd9dbca5 326 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS05825 efa5332376ba541abfb385e0ddd01090 117 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS05825 efa5332376ba541abfb385e0ddd01090 117 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.1E-41 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS05825 efa5332376ba541abfb385e0ddd01090 117 Gene3D G3DSA:1.10.1900.20 55 117 8.6E-30 T 09-03-2017 L21SP3_RS05825 efa5332376ba541abfb385e0ddd01090 117 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.7E-32 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS05825 efa5332376ba541abfb385e0ddd01090 117 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.7E-32 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS05825 efa5332376ba541abfb385e0ddd01090 117 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.7E-32 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS05825 efa5332376ba541abfb385e0ddd01090 117 SUPERFAMILY SSF74731 3 116 1.88E-39 T 09-03-2017 L21SP3_RS05825 efa5332376ba541abfb385e0ddd01090 117 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 22 71 0.008 T 09-03-2017 L21SP3_RS05825 efa5332376ba541abfb385e0ddd01090 117 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 25.32 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS05825 efa5332376ba541abfb385e0ddd01090 117 Pfam PF00453 Ribosomal protein L20 4 109 3.0E-38 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS08685 6a3b48723afdbb8448b062eed4598cbe 278 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 273 39.876 T 09-03-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS08685 6a3b48723afdbb8448b062eed4598cbe 278 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 264 2.6E-60 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS08685 6a3b48723afdbb8448b062eed4598cbe 278 SUPERFAMILY SSF51351 1 272 3.49E-89 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS08685 6a3b48723afdbb8448b062eed4598cbe 278 Gene3D G3DSA:3.20.20.70 1 146 8.2E-57 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS08685 6a3b48723afdbb8448b062eed4598cbe 278 Gene3D G3DSA:3.20.20.70 156 275 2.5E-48 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS08685 6a3b48723afdbb8448b062eed4598cbe 278 Pfam PF00121 Triosephosphate isomerase 156 270 3.1E-43 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS08685 6a3b48723afdbb8448b062eed4598cbe 278 Pfam PF00121 Triosephosphate isomerase 5 146 6.2E-47 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS08685 6a3b48723afdbb8448b062eed4598cbe 278 ProSitePatterns PS00171 Triosephosphate isomerase active site. 188 198 - T 09-03-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 L21SP3_RS01645 84b17a881a6f863157e3593f1b903fe8 783 Pfam PF03030 Inorganic H+ pyrophosphatase 40 764 1.9E-267 T 09-03-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 L21SP3_RS01645 84b17a881a6f863157e3593f1b903fe8 783 PIRSF PIRSF001265 23 777 2.8E-259 T 09-03-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 L21SP3_RS01645 84b17a881a6f863157e3593f1b903fe8 783 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 33 770 2.5E-231 T 09-03-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 L21SP3_RS01645 84b17a881a6f863157e3593f1b903fe8 783 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 29 769 24.075 T 09-03-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 L21SP3_RS11140 3cfe6ffb8607a771266057097f04b47b 568 Pfam PF13229 Right handed beta helix region 420 534 1.8E-6 T 09-03-2017 L21SP3_RS11140 3cfe6ffb8607a771266057097f04b47b 568 Gene3D G3DSA:2.160.20.10 342 534 1.5E-10 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS11140 3cfe6ffb8607a771266057097f04b47b 568 Gene3D G3DSA:2.160.20.10 37 121 1.5E-10 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS11140 3cfe6ffb8607a771266057097f04b47b 568 Gene3D G3DSA:2.160.20.10 230 328 1.0E-10 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS11140 3cfe6ffb8607a771266057097f04b47b 568 SUPERFAMILY SSF51126 233 326 5.62E-24 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS11140 3cfe6ffb8607a771266057097f04b47b 568 SUPERFAMILY SSF51126 417 532 5.62E-24 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS11140 3cfe6ffb8607a771266057097f04b47b 568 SUPERFAMILY SSF51126 40 131 5.62E-24 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS02625 21ba302f64bf9dc3efa96ea829d8b319 424 Pfam PF01145 SPFH domain / Band 7 family 55 280 9.8E-22 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS02625 21ba302f64bf9dc3efa96ea829d8b319 424 SUPERFAMILY SSF117892 151 272 3.4E-5 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS06100 c7cd163e8fad18bce7a4f69be8e56abb 71 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 4.7E-35 T 09-03-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 L21SP3_RS06100 c7cd163e8fad18bce7a4f69be8e56abb 71 Gene3D G3DSA:2.40.50.140 1 70 8.8E-34 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS06100 c7cd163e8fad18bce7a4f69be8e56abb 71 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 71 24.29 T 09-03-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 L21SP3_RS06100 c7cd163e8fad18bce7a4f69be8e56abb 71 SUPERFAMILY SSF50249 1 70 2.86E-25 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS06100 c7cd163e8fad18bce7a4f69be8e56abb 71 Pfam PF01176 Translation initiation factor 1A / IF-1 9 70 4.5E-26 T 09-03-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 L21SP3_RS10245 a7c237ff8740840aa45f01ef916806a4 330 SUPERFAMILY SSF53098 175 321 1.67E-24 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS10245 a7c237ff8740840aa45f01ef916806a4 330 Pfam PF00665 Integrase core domain 178 280 8.0E-13 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS10245 a7c237ff8740840aa45f01ef916806a4 330 ProSitePatterns PS01043 Transposases, IS30 family, signature. 268 284 - T 09-03-2017 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 L21SP3_RS10245 a7c237ff8740840aa45f01ef916806a4 330 Gene3D G3DSA:3.30.420.10 176 322 3.0E-13 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS10245 a7c237ff8740840aa45f01ef916806a4 330 Pfam PF13936 Helix-turn-helix domain 4 45 4.8E-14 T 09-03-2017 IPR025246 Transposase IS30-like HTH domain L21SP3_RS03910 b6214f949d55c9eb2b991b22d9269dbc 589 SUPERFAMILY SSF69318 508 568 3.01E-10 T 09-03-2017 L21SP3_RS03910 b6214f949d55c9eb2b991b22d9269dbc 589 SUPERFAMILY SSF69318 101 365 3.01E-10 T 09-03-2017 L21SP3_RS03910 b6214f949d55c9eb2b991b22d9269dbc 589 Gene3D G3DSA:2.60.40.10 10 84 6.6E-4 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 SUPERFAMILY SSF54849 138 204 6.18E-21 T 09-03-2017 L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 527 3.4E-249 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 Hamap MF_00600 60 kDa chaperonin [groL]. 2 540 39.662 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 09-03-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 PRINTS PR00298 60kDa chaperonin signature 27 53 1.4E-69 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 PRINTS PR00298 60kDa chaperonin signature 350 375 1.4E-69 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 PRINTS PR00298 60kDa chaperonin signature 398 419 1.4E-69 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 PRINTS PR00298 60kDa chaperonin signature 268 291 1.4E-69 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 PRINTS PR00298 60kDa chaperonin signature 83 110 1.4E-69 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 524 5.7E-97 T 09-03-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 Gene3D G3DSA:1.10.560.10 4 187 8.6E-44 T 09-03-2017 IPR027413 GroEL-like equatorial domain L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 SUPERFAMILY SSF48592 406 521 9.92E-73 T 09-03-2017 L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 SUPERFAMILY SSF48592 7 134 9.92E-73 T 09-03-2017 L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 SUPERFAMILY SSF52029 184 376 2.79E-82 T 09-03-2017 IPR027409 GroEL-like apical domain L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 Gene3D G3DSA:3.50.7.10 188 367 4.0E-97 T 09-03-2017 IPR027409 GroEL-like apical domain L21SP3_RS01955 d37aeb1f9b8954a8cda25dc2d08c0b33 541 Gene3D G3DSA:1.10.560.10 368 518 2.1E-40 T 09-03-2017 IPR027413 GroEL-like equatorial domain L21SP3_RS09780 41c37e3e548b43c342182660fcd7ef14 252 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 252 31.496 T 09-03-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS09780 41c37e3e548b43c342182660fcd7ef14 252 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 11 247 2.0E-58 T 09-03-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS09780 41c37e3e548b43c342182660fcd7ef14 252 Pfam PF01416 tRNA pseudouridine synthase 153 252 2.6E-26 T 09-03-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS09780 41c37e3e548b43c342182660fcd7ef14 252 Pfam PF01416 tRNA pseudouridine synthase 16 108 8.3E-11 T 09-03-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS09780 41c37e3e548b43c342182660fcd7ef14 252 Gene3D G3DSA:3.30.70.580 10 108 4.9E-32 T 09-03-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS09780 41c37e3e548b43c342182660fcd7ef14 252 Gene3D G3DSA:3.30.70.660 115 250 1.1E-45 T 09-03-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS09780 41c37e3e548b43c342182660fcd7ef14 252 SUPERFAMILY SSF55120 11 252 3.31E-77 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS09780 41c37e3e548b43c342182660fcd7ef14 252 PIRSF PIRSF001430 9 252 6.0E-74 T 09-03-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 L21SP3_RS01135 eaeff296f3c1075245814409b12b567d 362 SUPERFAMILY SSF54534 195 297 7.2E-36 T 09-03-2017 L21SP3_RS01135 eaeff296f3c1075245814409b12b567d 362 Pfam PF13624 SurA N-terminal domain 11 166 3.4E-16 T 09-03-2017 L21SP3_RS01135 eaeff296f3c1075245814409b12b567d 362 Gene3D G3DSA:3.10.50.40 189 319 1.8E-51 T 09-03-2017 L21SP3_RS01135 eaeff296f3c1075245814409b12b567d 362 SUPERFAMILY SSF109998 52 223 2.94E-35 T 09-03-2017 IPR027304 Trigger factor/SurA domain L21SP3_RS01135 eaeff296f3c1075245814409b12b567d 362 Pfam PF13616 PPIC-type PPIASE domain 195 296 4.5E-33 T 09-03-2017 L21SP3_RS03485 46df8a999394df43866fb8b0205ce3bf 398 Pfam PF00535 Glycosyl transferase family 2 42 202 4.1E-24 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 L21SP3_RS03485 46df8a999394df43866fb8b0205ce3bf 398 Pfam PF04138 GtrA-like protein 277 394 2.2E-21 T 09-03-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 L21SP3_RS03485 46df8a999394df43866fb8b0205ce3bf 398 Gene3D G3DSA:3.90.550.10 39 173 6.7E-20 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS03485 46df8a999394df43866fb8b0205ce3bf 398 SUPERFAMILY SSF53448 40 284 4.71E-32 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS05640 c14ef2276320d3eb56f9d27e6d03d5e5 210 Gene3D G3DSA:3.40.50.720 23 148 2.0E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS05640 c14ef2276320d3eb56f9d27e6d03d5e5 210 Pfam PF00899 ThiF family 21 140 5.4E-28 T 09-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 L21SP3_RS05640 c14ef2276320d3eb56f9d27e6d03d5e5 210 TIGRFAM TIGR02354 thiF_fam2: thiamine biosynthesis protein ThiF 16 204 2.0E-54 T 09-03-2017 IPR012729 Thiamine biosynthesis protein ThiF L21SP3_RS05640 c14ef2276320d3eb56f9d27e6d03d5e5 210 SUPERFAMILY SSF69572 22 204 2.49E-36 T 09-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 SUPERFAMILY SSF64484 1108 1269 0.0 T 09-03-2017 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 SUPERFAMILY SSF64484 10 930 0.0 T 09-03-2017 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 SUPERFAMILY SSF64484 1310 1383 0.0 T 09-03-2017 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 Pfam PF05000 RNA polymerase Rpb1, domain 4 667 749 4.7E-11 T 09-03-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 Gene3D G3DSA:2.40.50.100 1131 1188 1.7E-9 T 09-03-2017 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 Pfam PF04998 RNA polymerase Rpb1, domain 5 752 1250 4.5E-67 T 09-03-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1392 10.029 T 09-03-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 15 1269 0.0 T 09-03-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 Pfam PF00623 RNA polymerase Rpb1, domain 2 339 390 3.5E-8 T 09-03-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 Pfam PF00623 RNA polymerase Rpb1, domain 2 383 480 1.3E-25 T 09-03-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 Gene3D G3DSA:2.40.50.100 992 1035 1.0E-5 T 09-03-2017 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 Pfam PF04997 RNA polymerase Rpb1, domain 1 11 337 1.7E-83 T 09-03-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 Gene3D G3DSA:2.40.40.20 344 371 2.4E-35 T 09-03-2017 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 Gene3D G3DSA:2.40.40.20 412 484 2.4E-35 T 09-03-2017 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 SMART SM00663 230 509 3.6E-161 T 09-03-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS10795 608cc230d19f6851ad38a54cab864954 1419 Pfam PF04983 RNA polymerase Rpb1, domain 3 484 637 7.3E-22 T 09-03-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS00230 0bd1645e57c98fe8af0ee4b4554d95d0 175 TIGRFAM TIGR02989 Sig-70_gvs1: RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family 12 168 2.0E-38 T 09-03-2017 IPR014331 RNA polymerase sigma-70 ECF-like, Rhodopirellula baltica L21SP3_RS00230 0bd1645e57c98fe8af0ee4b4554d95d0 175 Pfam PF08281 Sigma-70, region 4 113 164 9.8E-7 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS00230 0bd1645e57c98fe8af0ee4b4554d95d0 175 Pfam PF04542 Sigma-70 region 2 18 80 4.0E-11 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS00230 0bd1645e57c98fe8af0ee4b4554d95d0 175 SUPERFAMILY SSF88659 108 167 3.36E-9 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS00230 0bd1645e57c98fe8af0ee4b4554d95d0 175 Gene3D G3DSA:1.10.1740.10 6 96 1.0E-16 T 09-03-2017 L21SP3_RS00230 0bd1645e57c98fe8af0ee4b4554d95d0 175 SUPERFAMILY SSF88946 7 86 1.52E-14 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS00230 0bd1645e57c98fe8af0ee4b4554d95d0 175 Gene3D G3DSA:1.10.10.10 110 168 1.2E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS00230 0bd1645e57c98fe8af0ee4b4554d95d0 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 166 8.9E-20 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10405 6d9810d4c5f1af642c0c11701f2da5c2 475 SUPERFAMILY SSF53649 30 445 4.8E-118 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS10405 6d9810d4c5f1af642c0c11701f2da5c2 475 Gene3D G3DSA:3.30.1120.10 380 446 2.5E-11 T 09-03-2017 L21SP3_RS10405 6d9810d4c5f1af642c0c11701f2da5c2 475 Gene3D G3DSA:3.40.720.10 29 379 1.3E-109 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS10405 6d9810d4c5f1af642c0c11701f2da5c2 475 Pfam PF00884 Sulfatase 32 366 1.2E-70 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 Gene3D G3DSA:3.40.50.1820 89 387 1.7E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 Gene3D G3DSA:3.40.50.1820 8 24 1.7E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 Gene3D G3DSA:3.40.50.1820 417 717 7.7E-45 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 Gene3D G3DSA:1.10.238.10 25 88 2.7E-9 T 09-03-2017 IPR011992 EF-hand domain pair L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 SUPERFAMILY SSF47473 502 518 2.66E-11 T 09-03-2017 IPR011992 EF-hand domain pair L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 SUPERFAMILY SSF47473 25 92 2.66E-11 T 09-03-2017 IPR011992 EF-hand domain pair L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 SUPERFAMILY SSF53474 416 717 9.21E-39 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 Pfam PF00561 alpha/beta hydrolase fold 450 555 5.4E-14 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 ProSitePatterns PS00018 EF-hand calcium-binding domain. 60 72 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 Pfam PF13202 EF hand 27 49 9.2E-5 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 ProSitePatterns PS00018 EF-hand calcium-binding domain. 34 46 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 SUPERFAMILY SSF53474 323 360 1.5E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 SUPERFAMILY SSF53474 99 274 1.5E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 PRINTS PR00412 Epoxide hydrolase signature 476 491 1.7E-6 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 PRINTS PR00412 Epoxide hydrolase signature 528 541 1.7E-6 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 PRINTS PR00412 Epoxide hydrolase signature 456 474 1.7E-6 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 PRINTS PR00412 Epoxide hydrolase signature 692 714 1.7E-6 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 L21SP3_RS08285 167dc5c508e8eec8b332613348101454 874 Pfam PF10503 Esterase PHB depolymerase 111 245 6.0E-10 T 09-03-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 L21SP3_RS08220 647e6edb02bbfe0fb9c5fdded213e8ff 455 Pfam PF13192 Thioredoxin domain 364 444 2.2E-6 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS08220 647e6edb02bbfe0fb9c5fdded213e8ff 455 Gene3D G3DSA:3.40.30.10 367 444 3.4E-11 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS08220 647e6edb02bbfe0fb9c5fdded213e8ff 455 Gene3D G3DSA:3.20.20.210 1 330 4.8E-65 T 09-03-2017 L21SP3_RS08220 647e6edb02bbfe0fb9c5fdded213e8ff 455 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 3 330 2.2E-62 T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 L21SP3_RS08220 647e6edb02bbfe0fb9c5fdded213e8ff 455 SUPERFAMILY SSF51726 1 331 3.27E-60 T 09-03-2017 L21SP3_RS08220 647e6edb02bbfe0fb9c5fdded213e8ff 455 SUPERFAMILY SSF52833 371 444 1.23E-8 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS11625 193a12ee14af6be4113ae8741a0727f5 268 SUPERFAMILY SSF53335 115 268 3.32E-13 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS11625 193a12ee14af6be4113ae8741a0727f5 268 Pfam PF01555 DNA methylase 16 97 1.0E-17 T 09-03-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 L21SP3_RS11625 193a12ee14af6be4113ae8741a0727f5 268 Pfam PF01555 DNA methylase 141 268 3.6E-6 T 09-03-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 L21SP3_RS11625 193a12ee14af6be4113ae8741a0727f5 268 Gene3D G3DSA:3.40.50.150 16 102 2.2E-18 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS11625 193a12ee14af6be4113ae8741a0727f5 268 Gene3D G3DSA:3.40.50.150 135 268 4.0E-8 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS11625 193a12ee14af6be4113ae8741a0727f5 268 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 58 76 3.2E-9 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS11625 193a12ee14af6be4113ae8741a0727f5 268 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 81 101 3.2E-9 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 L21SP3_RS11625 193a12ee14af6be4113ae8741a0727f5 268 SUPERFAMILY SSF53335 7 101 1.42E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS01170 259ff992f62c2497d69e2e900af1bca3 319 SUPERFAMILY SSF117892 55 215 1.03E-17 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS01170 259ff992f62c2497d69e2e900af1bca3 319 PIRSF PIRSF005651 1 316 6.2E-95 T 09-03-2017 IPR010200 HflC GO:0016021|GO:0052547 L21SP3_RS01170 259ff992f62c2497d69e2e900af1bca3 319 Pfam PF01145 SPFH domain / Band 7 family 27 225 7.4E-25 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS01170 259ff992f62c2497d69e2e900af1bca3 319 SMART SM00244 23 209 4.2E-20 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS01170 259ff992f62c2497d69e2e900af1bca3 319 TIGRFAM TIGR01932 hflC: HflC protein 11 306 1.4E-80 T 09-03-2017 IPR010200 HflC GO:0016021|GO:0052547 L21SP3_RS04860 d5a4a8e9a1736a303b855ac1d7bed8f1 486 Pfam PF13440 Polysaccharide biosynthesis protein 5 258 1.6E-6 T 09-03-2017 L21SP3_RS05430 036f3a8255cc6b9748b5f033ad0c9a91 303 Gene3D G3DSA:3.40.190.100 130 252 5.9E-39 T 09-03-2017 L21SP3_RS05430 036f3a8255cc6b9748b5f033ad0c9a91 303 SUPERFAMILY SSF53850 47 300 9.37E-75 T 09-03-2017 L21SP3_RS05430 036f3a8255cc6b9748b5f033ad0c9a91 303 Gene3D G3DSA:3.40.190.10 45 129 6.7E-22 T 09-03-2017 L21SP3_RS05430 036f3a8255cc6b9748b5f033ad0c9a91 303 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 48 290 1.2E-64 T 09-03-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 L21SP3_RS01165 b5f8c97bfb281dd8a699ccb9da17c3aa 321 SUPERFAMILY SSF117892 106 219 7.59E-22 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS01165 b5f8c97bfb281dd8a699ccb9da17c3aa 321 SMART SM00244 31 212 4.6E-25 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS01165 b5f8c97bfb281dd8a699ccb9da17c3aa 321 TIGRFAM TIGR01933 hflK: HflK protein 33 312 2.2E-83 T 09-03-2017 IPR010201 HflK GO:0016021 L21SP3_RS01165 b5f8c97bfb281dd8a699ccb9da17c3aa 321 Pfam PF01145 SPFH domain / Band 7 family 35 228 3.3E-27 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS04565 80b39cb1f5b807276c87b25b09d8bad8 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 3.3E-6 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS04565 80b39cb1f5b807276c87b25b09d8bad8 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 3.3E-6 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS04565 80b39cb1f5b807276c87b25b09d8bad8 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 113 129 3.3E-6 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS04565 80b39cb1f5b807276c87b25b09d8bad8 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 3.3E-6 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS04565 80b39cb1f5b807276c87b25b09d8bad8 305 Gene3D G3DSA:3.20.20.70 7 297 2.3E-57 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS04565 80b39cb1f5b807276c87b25b09d8bad8 305 SMART SM01130 10 299 2.5E-39 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS04565 80b39cb1f5b807276c87b25b09d8bad8 305 SUPERFAMILY SSF51569 12 297 5.34E-52 T 09-03-2017 L21SP3_RS04565 80b39cb1f5b807276c87b25b09d8bad8 305 Pfam PF00701 Dihydrodipicolinate synthetase family 12 295 2.4E-34 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS04565 80b39cb1f5b807276c87b25b09d8bad8 305 PIRSF PIRSF001365 7 300 3.2E-49 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 L21SP3_RS10880 da29f7dd43408ab7b75139f74479acb4 544 SUPERFAMILY SSF53649 29 530 1.09E-149 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS10880 da29f7dd43408ab7b75139f74479acb4 544 ProSitePatterns PS00149 Sulfatases signature 2. 126 136 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS10880 da29f7dd43408ab7b75139f74479acb4 544 Pfam PF00884 Sulfatase 31 429 3.1E-83 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS10880 da29f7dd43408ab7b75139f74479acb4 544 Gene3D G3DSA:3.30.1120.10 462 536 7.3E-24 T 09-03-2017 L21SP3_RS10880 da29f7dd43408ab7b75139f74479acb4 544 Gene3D G3DSA:3.40.720.10 28 458 1.2E-132 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS07770 834dcb7bf4a76dbad37709c4b9b8db25 862 Gene3D G3DSA:3.40.50.300 425 722 4.9E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07770 834dcb7bf4a76dbad37709c4b9b8db25 862 SMART SM00382 486 689 0.0022 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS07770 834dcb7bf4a76dbad37709c4b9b8db25 862 SUPERFAMILY SSF46785 753 818 1.26E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS07770 834dcb7bf4a76dbad37709c4b9b8db25 862 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 6 172 8.9E-17 T 09-03-2017 IPR025199 DNA translocase FtsK, 4TM region L21SP3_RS07770 834dcb7bf4a76dbad37709c4b9b8db25 862 SUPERFAMILY SSF52540 423 726 4.0E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07770 834dcb7bf4a76dbad37709c4b9b8db25 862 Pfam PF01580 FtsK/SpoIIIE family 464 655 1.8E-49 T 09-03-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 L21SP3_RS07770 834dcb7bf4a76dbad37709c4b9b8db25 862 Pfam PF09397 Ftsk gamma domain 753 814 1.5E-23 T 09-03-2017 IPR018541 FtsK gamma domain L21SP3_RS07770 834dcb7bf4a76dbad37709c4b9b8db25 862 SMART SM00843 751 816 2.2E-28 T 09-03-2017 IPR018541 FtsK gamma domain L21SP3_RS08010 0744cf0d182f0ab05fbcc6921815112f 337 SUPERFAMILY SSF101478 33 319 2.09E-16 T 09-03-2017 IPR005502 ADP-ribosylation/Crystallin J1 L21SP3_RS08010 0744cf0d182f0ab05fbcc6921815112f 337 Pfam PF03747 ADP-ribosylglycohydrolase 40 319 5.3E-23 T 09-03-2017 IPR005502 ADP-ribosylation/Crystallin J1 L21SP3_RS03345 b270f15d8ca24e49710d85407d80e2c3 329 Gene3D G3DSA:3.40.50.720 1 174 2.8E-55 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS03345 b270f15d8ca24e49710d85407d80e2c3 329 Gene3D G3DSA:3.90.25.10 175 321 1.2E-32 T 09-03-2017 L21SP3_RS03345 b270f15d8ca24e49710d85407d80e2c3 329 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 313 8.3E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS03345 b270f15d8ca24e49710d85407d80e2c3 329 SUPERFAMILY SSF51735 1 321 2.24E-82 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS05605 e2e3cf4d45efb60d90e34b4c316209d6 158 SUPERFAMILY SSF52218 1 156 7.99E-38 T 09-03-2017 IPR029039 Flavoprotein-like domain L21SP3_RS05605 e2e3cf4d45efb60d90e34b4c316209d6 158 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 09-03-2017 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 L21SP3_RS05605 e2e3cf4d45efb60d90e34b4c316209d6 158 Gene3D G3DSA:3.40.50.360 1 156 1.2E-43 T 09-03-2017 IPR029039 Flavoprotein-like domain L21SP3_RS05605 e2e3cf4d45efb60d90e34b4c316209d6 158 Pfam PF12724 Flavodoxin domain 5 73 1.5E-11 T 09-03-2017 IPR026816 Flavodoxin domain L21SP3_RS09980 7fe9bf33998ac0570a2847c099400a30 287 SUPERFAMILY SSF56300 221 258 2.04E-18 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS09980 7fe9bf33998ac0570a2847c099400a30 287 SUPERFAMILY SSF56300 9 134 2.04E-18 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS09980 7fe9bf33998ac0570a2847c099400a30 287 Gene3D G3DSA:3.60.21.10 12 137 2.8E-18 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS09980 7fe9bf33998ac0570a2847c099400a30 287 Gene3D G3DSA:3.60.21.10 223 258 2.8E-18 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS09980 7fe9bf33998ac0570a2847c099400a30 287 Pfam PF00149 Calcineurin-like phosphoesterase 11 238 4.7E-8 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 L21SP3_RS03565 b1df3e497f15e49c0eda2232fc3d1856 377 Gene3D G3DSA:3.40.1390.20 226 363 3.2E-29 T 09-03-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like L21SP3_RS03565 b1df3e497f15e49c0eda2232fc3d1856 377 SUPERFAMILY SSF52540 13 234 6.38E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03565 b1df3e497f15e49c0eda2232fc3d1856 377 Gene3D G3DSA:3.40.50.300 13 225 1.1E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03565 b1df3e497f15e49c0eda2232fc3d1856 377 SUPERFAMILY SSF75138 227 350 1.05E-24 T 09-03-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like L21SP3_RS03565 b1df3e497f15e49c0eda2232fc3d1856 377 Pfam PF13500 AAA domain 15 224 8.1E-30 T 09-03-2017 L21SP3_RS03565 b1df3e497f15e49c0eda2232fc3d1856 377 Pfam PF07085 DRTGG domain 230 342 5.0E-24 T 09-03-2017 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 L21SP3_RS02940 b9257062de5b6202f80e8d759d223c01 490 Gene3D G3DSA:3.80.30.20 187 412 1.4E-34 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe L21SP3_RS02940 b9257062de5b6202f80e8d759d223c01 490 Pfam PF04055 Radical SAM superfamily 189 362 4.6E-13 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS02940 b9257062de5b6202f80e8d759d223c01 490 SMART SM00729 185 416 6.3E-21 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP3_RS02940 b9257062de5b6202f80e8d759d223c01 490 SUPERFAMILY SSF102114 179 414 1.26E-19 T 09-03-2017 L21SP3_RS07445 dc66ae0eab522ada1d196f14cd594356 185 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 140 168 - T 09-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 L21SP3_RS07445 dc66ae0eab522ada1d196f14cd594356 185 Pfam PF12464 Maltose acetyltransferase 7 59 2.9E-11 T 09-03-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 L21SP3_RS07445 dc66ae0eab522ada1d196f14cd594356 185 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 132 166 1.4E-8 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS07445 dc66ae0eab522ada1d196f14cd594356 185 SUPERFAMILY SSF51161 2 184 1.23E-48 T 09-03-2017 IPR011004 Trimeric LpxA-like L21SP3_RS07445 dc66ae0eab522ada1d196f14cd594356 185 SMART SM01266 5 60 3.1E-14 T 09-03-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 L21SP3_RS07445 dc66ae0eab522ada1d196f14cd594356 185 Gene3D G3DSA:2.160.10.10 2 185 1.6E-59 T 09-03-2017 L21SP3_RS02685 02af303dd53f4d8b1600cee7117bfb97 725 Gene3D G3DSA:2.60.40.10 364 464 1.0E-12 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS02685 02af303dd53f4d8b1600cee7117bfb97 725 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 530 673 4.4E-16 T 09-03-2017 L21SP3_RS02685 02af303dd53f4d8b1600cee7117bfb97 725 SUPERFAMILY SSF48726 364 463 6.64E-12 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS02685 02af303dd53f4d8b1600cee7117bfb97 725 SUPERFAMILY SSF49899 465 677 1.9E-20 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS02685 02af303dd53f4d8b1600cee7117bfb97 725 SMART SM00409 370 463 5.2E-4 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS02685 02af303dd53f4d8b1600cee7117bfb97 725 Pfam PF13927 Immunoglobulin domain 364 448 7.7E-9 T 09-03-2017 L21SP3_RS02685 02af303dd53f4d8b1600cee7117bfb97 725 Gene3D G3DSA:2.60.120.200 465 680 1.1E-21 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10510 977aeabd6dfc594a589d43167279b7eb 741 Pfam PF00474 Sodium:solute symporter family 410 540 1.3E-13 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS07550 7ef3f72beb2d03f5acc097282286471b 70 Pfam PF13783 Domain of unknown function (DUF4177) 5 70 3.4E-10 T 09-03-2017 IPR025234 Protein of unknown function DUF4177 L21SP3_RS08070 97e79ebf37db78cb7bfa70d88d7b90f5 75 Gene3D G3DSA:1.20.1440.60 4 75 1.8E-18 T 09-03-2017 IPR012657 23S rRNA-intervening sequence protein L21SP3_RS08070 97e79ebf37db78cb7bfa70d88d7b90f5 75 SUPERFAMILY SSF158446 4 75 9.68E-23 T 09-03-2017 L21SP3_RS08070 97e79ebf37db78cb7bfa70d88d7b90f5 75 Pfam PF05635 23S rRNA-intervening sequence protein 6 75 2.4E-20 T 09-03-2017 IPR012657 23S rRNA-intervening sequence protein L21SP3_RS08070 97e79ebf37db78cb7bfa70d88d7b90f5 75 TIGRFAM TIGR02436 TIGR02436: four helix bundle protein 10 75 2.7E-18 T 09-03-2017 IPR012657 23S rRNA-intervening sequence protein L21SP3_RS03305 ca9ef558a29fef42872812b93a030e14 478 PIRSF PIRSF028846 41 475 3.2E-175 T 09-03-2017 IPR008313 Metal-independent alpha-mannosidase L21SP3_RS03305 ca9ef558a29fef42872812b93a030e14 478 Gene3D G3DSA:1.50.10.10 48 475 8.8E-174 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS03305 ca9ef558a29fef42872812b93a030e14 478 SUPERFAMILY SSF48208 33 475 9.64E-170 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS03305 ca9ef558a29fef42872812b93a030e14 478 SMART SM01149 63 464 5.9E-225 T 09-03-2017 IPR008313 Metal-independent alpha-mannosidase L21SP3_RS03305 ca9ef558a29fef42872812b93a030e14 478 Pfam PF06824 Protein of unknown function (DUF1237) 63 463 6.4E-157 T 09-03-2017 IPR008313 Metal-independent alpha-mannosidase L21SP3_RS11060 b3a6d5038ad7da5c363767fb78ea22da 542 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 329 538 1.0E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS11060 b3a6d5038ad7da5c363767fb78ea22da 542 SUPERFAMILY SSF161098 291 526 1.44E-31 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS11060 b3a6d5038ad7da5c363767fb78ea22da 542 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 290 534 1.3E-69 T 09-03-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 L21SP3_RS11060 b3a6d5038ad7da5c363767fb78ea22da 542 Gene3D G3DSA:1.10.3720.10 289 537 6.5E-43 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS11060 b3a6d5038ad7da5c363767fb78ea22da 542 Gene3D G3DSA:1.10.3720.10 20 42 6.5E-43 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS03420 618af91ac4ff9ca9f5716d2d09be09fa 315 Pfam PF01351 Ribonuclease HII 220 272 2.3E-5 T 09-03-2017 IPR024567 Ribonuclease HII/HIII domain L21SP3_RS03420 618af91ac4ff9ca9f5716d2d09be09fa 315 SUPERFAMILY SSF53098 4 34 8.5E-5 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS03420 618af91ac4ff9ca9f5716d2d09be09fa 315 SUPERFAMILY SSF53098 146 273 2.28E-6 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS03420 618af91ac4ff9ca9f5716d2d09be09fa 315 Gene3D G3DSA:3.30.420.10 4 69 2.9E-26 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS03420 618af91ac4ff9ca9f5716d2d09be09fa 315 Gene3D G3DSA:3.30.420.10 134 270 2.9E-26 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS02525 1746c22cda49401c4891aecf803411d0 328 SUPERFAMILY SSF51735 1 323 1.46E-90 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS02525 1746c22cda49401c4891aecf803411d0 328 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 325 1.4E-128 T 09-03-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 L21SP3_RS02525 1746c22cda49401c4891aecf803411d0 328 Gene3D G3DSA:3.90.25.10 171 327 8.5E-47 T 09-03-2017 L21SP3_RS02525 1746c22cda49401c4891aecf803411d0 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 251 2.7E-55 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 L21SP3_RS02525 1746c22cda49401c4891aecf803411d0 328 Gene3D G3DSA:3.40.50.720 1 170 3.7E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS02090 910c7ee73ab426fddf8d8a4674f412da 82 Pfam PF01084 Ribosomal protein S18 27 78 3.9E-21 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02090 910c7ee73ab426fddf8d8a4674f412da 82 TIGRFAM TIGR00165 S18: ribosomal protein bS18 16 80 5.7E-23 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02090 910c7ee73ab426fddf8d8a4674f412da 82 SUPERFAMILY SSF46911 11 81 2.62E-23 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02090 910c7ee73ab426fddf8d8a4674f412da 82 Gene3D G3DSA:4.10.640.10 19 81 2.1E-26 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02090 910c7ee73ab426fddf8d8a4674f412da 82 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 30 80 2.0E-11 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02090 910c7ee73ab426fddf8d8a4674f412da 82 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 5 82 15.773 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02090 910c7ee73ab426fddf8d8a4674f412da 82 PRINTS PR00974 Ribosomal protein S18 family signature 38 48 1.2E-10 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02090 910c7ee73ab426fddf8d8a4674f412da 82 PRINTS PR00974 Ribosomal protein S18 family signature 48 55 1.2E-10 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02090 910c7ee73ab426fddf8d8a4674f412da 82 PRINTS PR00974 Ribosomal protein S18 family signature 56 70 1.2E-10 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02090 910c7ee73ab426fddf8d8a4674f412da 82 PRINTS PR00974 Ribosomal protein S18 family signature 70 80 1.2E-10 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02765 64b333263ca222621b3193c75a761e16 252 Pfam PF07859 alpha/beta hydrolase fold 30 222 7.2E-18 T 09-03-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 L21SP3_RS02765 64b333263ca222621b3193c75a761e16 252 SUPERFAMILY SSF53474 9 227 3.13E-44 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS02765 64b333263ca222621b3193c75a761e16 252 Gene3D G3DSA:3.40.50.1820 2 237 5.3E-57 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS01685 01836f27b5eb4d99b0d48730bda7eb7c 318 Pfam PF03547 Membrane transport protein 7 127 4.4E-10 T 09-03-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 L21SP3_RS01685 01836f27b5eb4d99b0d48730bda7eb7c 318 Pfam PF03547 Membrane transport protein 159 303 3.4E-11 T 09-03-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 L21SP3_RS07840 5e0719c3ab80d10301730f00d87062da 291 SUPERFAMILY SSF55729 143 290 3.66E-13 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS07840 5e0719c3ab80d10301730f00d87062da 291 TIGRFAM TIGR03827 GNAT_ablB: putative beta-lysine N-acetyltransferase 26 290 9.3E-97 T 09-03-2017 IPR022525 Beta-lysine N-acetyltransferase GO:0016407 L21SP3_RS07840 5e0719c3ab80d10301730f00d87062da 291 Gene3D G3DSA:3.40.630.30 142 268 4.3E-9 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS03720 05723bca6deb600c4df8525457eb2019 124 Pfam PF01740 STAS domain 16 118 1.6E-15 T 09-03-2017 IPR002645 STAS domain L21SP3_RS03720 05723bca6deb600c4df8525457eb2019 124 Gene3D G3DSA:3.30.750.24 14 122 2.3E-31 T 09-03-2017 IPR002645 STAS domain L21SP3_RS03720 05723bca6deb600c4df8525457eb2019 124 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 14 116 1.0E-21 T 09-03-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 L21SP3_RS03720 05723bca6deb600c4df8525457eb2019 124 SUPERFAMILY SSF52091 14 121 4.51E-27 T 09-03-2017 IPR002645 STAS domain L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 Pfam PF07719 Tetratricopeptide repeat 153 186 1.2E-6 T 09-03-2017 IPR013105 Tetratricopeptide repeat 2 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 Gene3D G3DSA:1.25.40.10 61 267 1.8E-26 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 378 437 2.0E-11 T 09-03-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 290 349 3.0E-17 T 09-03-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 SUPERFAMILY SSF47789 286 353 6.93E-21 T 09-03-2017 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 SUPERFAMILY SSF81901 60 261 4.71E-25 T 09-03-2017 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 Gene3D G3DSA:1.10.150.20 372 439 3.6E-20 T 09-03-2017 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 Gene3D G3DSA:1.10.150.20 285 350 5.5E-25 T 09-03-2017 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 366 430 1.4E-18 T 09-03-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 280 342 1.9E-21 T 09-03-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 SMART SM00028 221 254 0.017 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 SMART SM00028 187 220 59.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 SMART SM00028 84 117 22.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 SMART SM00028 153 186 8.4E-4 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 SUPERFAMILY SSF47789 373 438 5.89E-17 T 09-03-2017 L21SP3_RS02605 647d673efb69361d40007be2b4171a9d 441 Pfam PF14559 Tetratricopeptide repeat 201 258 7.7E-8 T 09-03-2017 L21SP3_RS05350 1b8b174435ec9d9e46ca72854110895e 562 SUPERFAMILY SSF50969 181 427 1.1E-6 T 09-03-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like L21SP3_RS05350 1b8b174435ec9d9e46ca72854110895e 562 Pfam PF05935 Arylsulfotransferase (ASST) 40 499 8.7E-94 T 09-03-2017 IPR010262 Arylsulfotransferase L21SP3_RS11695 35e7a40e0e9f77aada77b4aa12f9e977 185 TIGRFAM TIGR04328 cas4_PREFRAN: CRISPR-associated protein Cas4, subtype PREFRAN 5 181 3.4E-69 T 09-03-2017 IPR027616 CRISPR-associated protein Cas4, PREFRAN subtype L21SP3_RS11695 35e7a40e0e9f77aada77b4aa12f9e977 185 Pfam PF01930 Domain of unknown function DUF83 8 180 1.1E-11 T 09-03-2017 IPR022765 Dna2/Cas4, domain of unknown function DUF83 L21SP3_RS11320 cd59624486f84b0a78d6ac77a2bb206b 59 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 3 59 18.019 T 09-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS11320 cd59624486f84b0a78d6ac77a2bb206b 59 Pfam PF01165 Ribosomal protein S21 6 53 5.0E-14 T 09-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS11320 cd59624486f84b0a78d6ac77a2bb206b 59 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 18 44 6.0E-4 T 09-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS11320 cd59624486f84b0a78d6ac77a2bb206b 59 PRINTS PR00976 Ribosomal protein S21 family signature 15 24 4.2E-6 T 09-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS11320 cd59624486f84b0a78d6ac77a2bb206b 59 PRINTS PR00976 Ribosomal protein S21 family signature 27 37 4.2E-6 T 09-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS11320 cd59624486f84b0a78d6ac77a2bb206b 59 PRINTS PR00976 Ribosomal protein S21 family signature 39 49 4.2E-6 T 09-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS11320 cd59624486f84b0a78d6ac77a2bb206b 59 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 5 54 2.6E-17 T 09-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS09785 6d1ee815d758ba7af4b98dd5ff1e3b81 432 SUPERFAMILY SSF53383 5 412 6.33E-68 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS09785 6d1ee815d758ba7af4b98dd5ff1e3b81 432 Gene3D G3DSA:3.90.1150.10 290 413 2.7E-16 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS09785 6d1ee815d758ba7af4b98dd5ff1e3b81 432 Gene3D G3DSA:3.40.640.10 53 289 2.7E-48 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS09785 6d1ee815d758ba7af4b98dd5ff1e3b81 432 Pfam PF00155 Aminotransferase class I and II 47 407 3.7E-39 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 L21SP3_RS05035 f7816b1a839dfddeeeef51773511e4ed 554 SUPERFAMILY SSF49785 414 549 5.95E-6 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS05035 f7816b1a839dfddeeeef51773511e4ed 554 Pfam PF08305 NPCBM/NEW2 domain 433 549 1.3E-8 T 09-03-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module L21SP3_RS11590 5273dc22934863aa9cd543dc89d3e196 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 L21SP3_RS11590 5273dc22934863aa9cd543dc89d3e196 108 SUPERFAMILY SSF52833 4 107 2.4E-39 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS11590 5273dc22934863aa9cd543dc89d3e196 108 Gene3D G3DSA:3.40.30.10 2 107 8.6E-38 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS11590 5273dc22934863aa9cd543dc89d3e196 108 Pfam PF00085 Thioredoxin 6 105 6.1E-34 T 09-03-2017 IPR013766 Thioredoxin domain GO:0045454 L21SP3_RS11590 5273dc22934863aa9cd543dc89d3e196 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 2.4E-39 T 09-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 L21SP3_RS11590 5273dc22934863aa9cd543dc89d3e196 108 PIRSF PIRSF000077 2 108 1.3E-40 T 09-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 L21SP3_RS11590 5273dc22934863aa9cd543dc89d3e196 108 PRINTS PR00421 Thioredoxin family signature 24 32 2.7E-9 T 09-03-2017 L21SP3_RS11590 5273dc22934863aa9cd543dc89d3e196 108 PRINTS PR00421 Thioredoxin family signature 32 41 2.7E-9 T 09-03-2017 L21SP3_RS11590 5273dc22934863aa9cd543dc89d3e196 108 PRINTS PR00421 Thioredoxin family signature 72 83 2.7E-9 T 09-03-2017 L21SP3_RS03445 ab853635186d3388809cf2b132a0b8f9 105 SMART SM00278 82 101 3.3 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP3_RS03445 ab853635186d3388809cf2b132a0b8f9 105 SMART SM00278 53 72 0.15 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 L21SP3_RS03445 ab853635186d3388809cf2b132a0b8f9 105 Gene3D G3DSA:1.10.150.280 35 104 3.8E-17 T 09-03-2017 L21SP3_RS03445 ab853635186d3388809cf2b132a0b8f9 105 SUPERFAMILY SSF47781 46 100 2.89E-15 T 09-03-2017 IPR010994 RuvA domain 2-like L21SP3_RS03445 ab853635186d3388809cf2b132a0b8f9 105 Pfam PF12836 Helix-hairpin-helix motif 44 100 1.2E-15 T 09-03-2017 L21SP3_RS09965 586a894bf74738d87326d4fc76708de6 267 PIRSF PIRSF000090 1 267 7.0E-66 T 09-03-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 L21SP3_RS09965 586a894bf74738d87326d4fc76708de6 267 SUPERFAMILY SSF52402 3 242 1.02E-55 T 09-03-2017 L21SP3_RS09965 586a894bf74738d87326d4fc76708de6 267 SMART SM00893 4 190 3.3E-53 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 L21SP3_RS09965 586a894bf74738d87326d4fc76708de6 267 Pfam PF01012 Electron transfer flavoprotein domain 5 176 7.5E-46 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 L21SP3_RS09965 586a894bf74738d87326d4fc76708de6 267 Gene3D G3DSA:3.40.50.620 3 263 4.2E-71 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 Gene3D G3DSA:3.30.470.20 248 345 4.0E-40 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 519 898 6.4E-92 T 09-03-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 Pfam PF00391 PEP-utilising enzyme, mobile domain 424 505 5.5E-28 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 Gene3D G3DSA:1.10.189.10 346 402 6.6E-29 T 09-03-2017 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 Gene3D G3DSA:3.50.30.10 403 508 8.9E-43 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 Gene3D G3DSA:1.20.80.30 116 202 1.6E-34 T 09-03-2017 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 Gene3D G3DSA:3.30.1490.20 204 246 6.4E-56 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 Gene3D G3DSA:3.30.1490.20 6 115 6.4E-56 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 790 808 - T 09-03-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 452 463 - T 09-03-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 307 361 9.0E-12 T 09-03-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 22 294 1.2E-47 T 09-03-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 SUPERFAMILY SSF56059 3 383 1.41E-136 T 09-03-2017 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 SUPERFAMILY SSF51621 513 581 6.81E-121 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 SUPERFAMILY SSF51621 610 899 6.81E-121 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 SUPERFAMILY SSF52009 388 514 2.49E-37 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 Gene3D G3DSA:3.20.20.60 534 900 5.2E-132 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP3_RS10590 4715472eae0ab2cee88a5e378901a9bd 901 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 4 594 1.8E-274 T 09-03-2017 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 L21SP3_RS11425 4b37c7c9c136f5c8727254caf5e8e2a7 336 PRINTS PR00394 RHS protein signature 151 170 2.6E-7 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11425 4b37c7c9c136f5c8727254caf5e8e2a7 336 PRINTS PR00394 RHS protein signature 128 148 2.6E-7 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11425 4b37c7c9c136f5c8727254caf5e8e2a7 336 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 100 184 5.6E-26 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 L21SP3_RS11760 e99ede6e3e90b0c69d4a102ddf828af5 100 SUPERFAMILY SSF51556 2 98 1.94E-16 T 09-03-2017 IPR032466 Metal-dependent hydrolase L21SP3_RS11760 e99ede6e3e90b0c69d4a102ddf828af5 100 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 20 36 - T 09-03-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 L21SP3_RS11760 e99ede6e3e90b0c69d4a102ddf828af5 100 Pfam PF01026 TatD related DNase 1 98 5.2E-16 T 09-03-2017 IPR001130 TatD family GO:0016788 L21SP3_RS11760 e99ede6e3e90b0c69d4a102ddf828af5 100 Gene3D G3DSA:3.20.20.140 1 97 5.2E-18 T 09-03-2017 L21SP3_RS00080 53c1b9b68c646ea2e56e17ee42cfc9ff 399 PIRSF PIRSF000106 17 399 1.2E-64 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 L21SP3_RS00080 53c1b9b68c646ea2e56e17ee42cfc9ff 399 SMART SM00919 183 397 9.2E-68 T 09-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 L21SP3_RS00080 53c1b9b68c646ea2e56e17ee42cfc9ff 399 SUPERFAMILY SSF51735 183 398 1.01E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS00080 53c1b9b68c646ea2e56e17ee42cfc9ff 399 Gene3D G3DSA:3.40.50.10380 38 180 6.7E-49 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 L21SP3_RS00080 53c1b9b68c646ea2e56e17ee42cfc9ff 399 Gene3D G3DSA:3.40.50.720 181 396 3.6E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS00080 53c1b9b68c646ea2e56e17ee42cfc9ff 399 Pfam PF03949 Malic enzyme, NAD binding domain 185 314 1.1E-10 T 09-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 L21SP3_RS00080 53c1b9b68c646ea2e56e17ee42cfc9ff 399 SMART SM01274 38 171 4.0E-64 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 L21SP3_RS00080 53c1b9b68c646ea2e56e17ee42cfc9ff 399 PRINTS PR00072 Malic enzyme signature 299 315 2.9E-7 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 L21SP3_RS00080 53c1b9b68c646ea2e56e17ee42cfc9ff 399 PRINTS PR00072 Malic enzyme signature 179 195 2.9E-7 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 L21SP3_RS00080 53c1b9b68c646ea2e56e17ee42cfc9ff 399 PRINTS PR00072 Malic enzyme signature 100 122 2.9E-7 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 L21SP3_RS00080 53c1b9b68c646ea2e56e17ee42cfc9ff 399 Pfam PF00390 Malic enzyme, N-terminal domain 44 170 7.1E-24 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 L21SP3_RS00080 53c1b9b68c646ea2e56e17ee42cfc9ff 399 SUPERFAMILY SSF53223 36 181 4.1E-47 T 09-03-2017 L21SP3_RS00325 7263acf279b985b3226e01081401ca32 393 SUPERFAMILY SSF53822 62 287 9.42E-27 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS00325 7263acf279b985b3226e01081401ca32 393 Gene3D G3DSA:3.40.50.2300 115 277 5.5E-27 T 09-03-2017 L21SP3_RS00325 7263acf279b985b3226e01081401ca32 393 SMART SM00342 301 384 4.6E-23 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS00325 7263acf279b985b3226e01081401ca32 393 Pfam PF12833 Helix-turn-helix domain 308 385 1.6E-19 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS00325 7263acf279b985b3226e01081401ca32 393 Gene3D G3DSA:1.10.10.60 284 337 5.4E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS00325 7263acf279b985b3226e01081401ca32 393 SUPERFAMILY SSF46689 338 388 2.33E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS00325 7263acf279b985b3226e01081401ca32 393 Gene3D G3DSA:1.10.10.60 338 386 3.6E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS00325 7263acf279b985b3226e01081401ca32 393 Pfam PF13377 Periplasmic binding protein-like domain 114 277 3.5E-25 T 09-03-2017 L21SP3_RS00325 7263acf279b985b3226e01081401ca32 393 Gene3D G3DSA:3.40.50.2300 19 114 1.3E-5 T 09-03-2017 L21SP3_RS08715 d4429fe5aeaad53b11d4222d4695c959 749 Gene3D G3DSA:3.90.226.10 718 739 7.4E-53 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS08715 d4429fe5aeaad53b11d4222d4695c959 749 Gene3D G3DSA:3.90.226.10 478 683 7.4E-53 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS08715 d4429fe5aeaad53b11d4222d4695c959 749 Pfam PF13180 PDZ domain 395 469 6.1E-10 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS08715 d4429fe5aeaad53b11d4222d4695c959 749 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 358 660 2.4E-81 T 09-03-2017 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 L21SP3_RS08715 d4429fe5aeaad53b11d4222d4695c959 749 SMART SM00228 394 465 5.5E-12 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS08715 d4429fe5aeaad53b11d4222d4695c959 749 Pfam PF03572 Peptidase family S41 504 679 3.7E-44 T 09-03-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 L21SP3_RS08715 d4429fe5aeaad53b11d4222d4695c959 749 Gene3D G3DSA:2.30.42.10 394 477 9.3E-22 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS08715 d4429fe5aeaad53b11d4222d4695c959 749 SUPERFAMILY SSF50156 366 486 7.23E-18 T 09-03-2017 IPR001478 PDZ domain GO:0005515 L21SP3_RS08715 d4429fe5aeaad53b11d4222d4695c959 749 SMART SM00245 467 681 9.6E-49 T 09-03-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 L21SP3_RS08715 d4429fe5aeaad53b11d4222d4695c959 749 SUPERFAMILY SSF52096 498 695 6.46E-61 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS08715 d4429fe5aeaad53b11d4222d4695c959 749 SUPERFAMILY SSF52096 326 412 6.46E-61 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS09095 fae41a2cf46afa74f7c67588dda1d884 265 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS09095 fae41a2cf46afa74f7c67588dda1d884 265 SUPERFAMILY SSF52540 3 233 8.72E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09095 fae41a2cf46afa74f7c67588dda1d884 265 Gene3D G3DSA:3.40.50.300 3 235 8.1E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09095 fae41a2cf46afa74f7c67588dda1d884 265 Pfam PF00005 ABC transporter 19 167 6.0E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS09095 fae41a2cf46afa74f7c67588dda1d884 265 SMART SM00382 27 217 9.8E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS03690 885f6b871c72ede2125891866b403fe4 351 Pfam PF02563 Polysaccharide biosynthesis/export protein 67 138 3.5E-17 T 09-03-2017 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 L21SP3_RS03690 885f6b871c72ede2125891866b403fe4 351 Gene3D G3DSA:3.10.560.10 235 319 4.7E-14 T 09-03-2017 L21SP3_RS03690 885f6b871c72ede2125891866b403fe4 351 Gene3D G3DSA:3.10.560.10 138 234 2.0E-18 T 09-03-2017 L21SP3_RS03690 885f6b871c72ede2125891866b403fe4 351 Gene3D G3DSA:3.30.1950.10 74 137 5.4E-14 T 09-03-2017 L21SP3_RS03690 885f6b871c72ede2125891866b403fe4 351 Pfam PF10531 SLBB domain 239 284 4.9E-5 T 09-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS03690 885f6b871c72ede2125891866b403fe4 351 Pfam PF10531 SLBB domain 147 178 3.8E-5 T 09-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS07625 4bd2284bf966231ae090a89a635271c1 270 Pfam PF11932 Protein of unknown function (DUF3450) 27 267 2.4E-32 T 09-03-2017 IPR016866 Uncharacterised conserved protein UCP028069 L21SP3_RS02835 f18a7c120c9e63a0ebacdeeb5557ca8b 336 PIRSF PIRSF006470 10 335 8.4E-93 T 09-03-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 L21SP3_RS02835 f18a7c120c9e63a0ebacdeeb5557ca8b 336 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 321 1.1E-83 T 09-03-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 L21SP3_RS02835 f18a7c120c9e63a0ebacdeeb5557ca8b 336 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 42 296 7.4E-71 T 09-03-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 L21SP3_RS02835 f18a7c120c9e63a0ebacdeeb5557ca8b 336 SUPERFAMILY SSF53850 153 288 5.7E-5 T 09-03-2017 L21SP3_RS11765 15d14339856cb64a9b00cc6b91f1c618 163 SUPERFAMILY SSF51556 3 162 7.95E-46 T 09-03-2017 IPR032466 Metal-dependent hydrolase L21SP3_RS11765 15d14339856cb64a9b00cc6b91f1c618 163 Pfam PF01026 TatD related DNase 4 162 3.7E-37 T 09-03-2017 IPR001130 TatD family GO:0016788 L21SP3_RS11765 15d14339856cb64a9b00cc6b91f1c618 163 Gene3D G3DSA:3.20.20.140 1 163 4.5E-47 T 09-03-2017 L21SP3_RS07100 5a7fa5dc9d2d2b54bbff9603876e152c 674 Pfam PF00474 Sodium:solute symporter family 459 587 1.7E-16 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS07100 5a7fa5dc9d2d2b54bbff9603876e152c 674 Pfam PF00474 Sodium:solute symporter family 40 333 5.0E-38 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS07100 5a7fa5dc9d2d2b54bbff9603876e152c 674 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 40 333 1.2E-59 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS02410 4baa4eb34c20d8fbf7532166d9cef7ae 318 Pfam PF13394 4Fe-4S single cluster domain 35 128 1.0E-4 T 09-03-2017 L21SP3_RS02410 4baa4eb34c20d8fbf7532166d9cef7ae 318 SUPERFAMILY SSF102114 31 228 2.35E-26 T 09-03-2017 L21SP3_RS02410 4baa4eb34c20d8fbf7532166d9cef7ae 318 Pfam PF04055 Radical SAM superfamily 32 188 2.7E-13 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS02410 4baa4eb34c20d8fbf7532166d9cef7ae 318 Gene3D G3DSA:3.20.20.70 33 235 1.5E-27 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS05965 a1ea7e28feeafc42040cfffa706e4989 404 Pfam PF00482 Type II secretion system (T2SS), protein F 273 395 3.2E-20 T 09-03-2017 IPR018076 Type II secretion system F domain L21SP3_RS05965 a1ea7e28feeafc42040cfffa706e4989 404 Pfam PF00482 Type II secretion system (T2SS), protein F 68 191 1.2E-26 T 09-03-2017 IPR018076 Type II secretion system F domain L21SP3_RS05965 a1ea7e28feeafc42040cfffa706e4989 404 PRINTS PR00812 Bacterial general secretion pathway protein F signature 384 403 1.6E-10 T 09-03-2017 IPR003004 GspF/PilC family L21SP3_RS05965 a1ea7e28feeafc42040cfffa706e4989 404 PRINTS PR00812 Bacterial general secretion pathway protein F signature 368 382 1.6E-10 T 09-03-2017 IPR003004 GspF/PilC family L21SP3_RS05965 a1ea7e28feeafc42040cfffa706e4989 404 PRINTS PR00812 Bacterial general secretion pathway protein F signature 163 191 1.6E-10 T 09-03-2017 IPR003004 GspF/PilC family L21SP3_RS06290 291cac349e98ead3eb8cb92b979a0ff4 319 SUPERFAMILY SSF54523 10 114 1.83E-8 T 09-03-2017 L21SP3_RS06290 291cac349e98ead3eb8cb92b979a0ff4 319 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 29 8.6E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS06290 291cac349e98ead3eb8cb92b979a0ff4 319 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 6 29 4.7E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS05690 d9d83f1b6830c272ed986a8be980ae5b 351 SUPERFAMILY SSF53756 15 351 1.22E-33 T 09-03-2017 L21SP3_RS05690 d9d83f1b6830c272ed986a8be980ae5b 351 Gene3D G3DSA:3.40.50.2000 197 350 8.5E-27 T 09-03-2017 L21SP3_RS05690 d9d83f1b6830c272ed986a8be980ae5b 351 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 197 339 7.2E-23 T 09-03-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 L21SP3_RS07620 10a5667a15561bee0b8c1d1fbb2e545c 483 Pfam PF01618 MotA/TolQ/ExbB proton channel family 334 452 1.6E-29 T 09-03-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 L21SP3_RS07620 10a5667a15561bee0b8c1d1fbb2e545c 483 PIRSF PIRSF037714 1 478 1.2E-109 T 09-03-2017 IPR017270 Putative MotA/TolQ/ExbB family protein L21SP3_RS05270 285023de5bb83393e13deffaced92a6a 370 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 103 4.4E-18 T 09-03-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 L21SP3_RS05270 285023de5bb83393e13deffaced92a6a 370 Pfam PF01872 RibD C-terminal domain 151 330 2.7E-38 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 L21SP3_RS05270 285023de5bb83393e13deffaced92a6a 370 Gene3D G3DSA:3.40.430.10 133 365 4.1E-61 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 L21SP3_RS05270 285023de5bb83393e13deffaced92a6a 370 Gene3D G3DSA:3.40.140.10 4 132 7.5E-30 T 09-03-2017 L21SP3_RS05270 285023de5bb83393e13deffaced92a6a 370 SUPERFAMILY SSF53927 4 148 8.63E-42 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 L21SP3_RS05270 285023de5bb83393e13deffaced92a6a 370 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 92 - T 09-03-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 L21SP3_RS05270 285023de5bb83393e13deffaced92a6a 370 PIRSF PIRSF006769 1 366 8.0E-114 T 09-03-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 L21SP3_RS05270 285023de5bb83393e13deffaced92a6a 370 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 7 330 4.4E-92 T 09-03-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 L21SP3_RS05270 285023de5bb83393e13deffaced92a6a 370 SUPERFAMILY SSF53597 149 361 1.03E-46 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 L21SP3_RS02675 21a66f3d89d0e92c39cf2052750f0a9f 587 Pfam PF02386 Cation transport protein 155 571 1.1E-58 T 09-03-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 L21SP3_RS05465 71e064c7e29c3b5c1506d0707676daf8 729 SUPERFAMILY SSF49899 370 594 4.54E-23 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05465 71e064c7e29c3b5c1506d0707676daf8 729 Gene3D G3DSA:2.60.120.200 119 278 2.1E-9 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05465 71e064c7e29c3b5c1506d0707676daf8 729 SMART SM00560 123 275 0.0054 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS05465 71e064c7e29c3b5c1506d0707676daf8 729 Gene3D G3DSA:2.60.40.10 617 674 7.3E-4 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS05465 71e064c7e29c3b5c1506d0707676daf8 729 Gene3D G3DSA:2.60.40.10 299 364 1.2E-4 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS05465 71e064c7e29c3b5c1506d0707676daf8 729 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 436 594 1.8E-12 T 09-03-2017 L21SP3_RS05465 71e064c7e29c3b5c1506d0707676daf8 729 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 119 276 9.5E-11 T 09-03-2017 L21SP3_RS05465 71e064c7e29c3b5c1506d0707676daf8 729 SUPERFAMILY SSF49899 105 278 2.32E-13 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05465 71e064c7e29c3b5c1506d0707676daf8 729 Gene3D G3DSA:2.60.120.200 372 595 4.7E-26 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS09175 f3c1ac1b34eb944029eea93af8459197 274 Gene3D G3DSA:3.60.15.10 1 258 4.7E-35 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS09175 f3c1ac1b34eb944029eea93af8459197 274 SUPERFAMILY SSF56281 2 272 3.54E-39 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS09175 f3c1ac1b34eb944029eea93af8459197 274 SMART SM00849 19 215 7.9E-6 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS09175 f3c1ac1b34eb944029eea93af8459197 274 Pfam PF00753 Metallo-beta-lactamase superfamily 20 98 1.1E-14 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS07065 829b83747b94f4584efb598d4c8fef9c 455 ProSitePatterns PS00523 Sulfatases signature 1. 79 91 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS07065 829b83747b94f4584efb598d4c8fef9c 455 Pfam PF00884 Sulfatase 33 336 9.4E-66 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS07065 829b83747b94f4584efb598d4c8fef9c 455 Gene3D G3DSA:3.30.1120.10 373 439 1.9E-21 T 09-03-2017 L21SP3_RS07065 829b83747b94f4584efb598d4c8fef9c 455 Gene3D G3DSA:3.40.720.10 31 372 5.3E-100 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS07065 829b83747b94f4584efb598d4c8fef9c 455 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 27 1.6E-4 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal L21SP3_RS07065 829b83747b94f4584efb598d4c8fef9c 455 Pfam PF16347 Domain of unknown function (DUF4976) 341 430 6.6E-11 T 09-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 L21SP3_RS07065 829b83747b94f4584efb598d4c8fef9c 455 SUPERFAMILY SSF53649 31 433 9.89E-119 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS01595 b69dfff859da3c2c8cb2023f3711b453 510 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 431 2.8E-90 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS01595 b69dfff859da3c2c8cb2023f3711b453 510 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 151 176 - T 09-03-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 L21SP3_RS01595 b69dfff859da3c2c8cb2023f3711b453 510 Pfam PF00474 Sodium:solute symporter family 35 423 3.4E-65 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS08675 a1ad0d3f578b9a71a17cf785e3b90e80 626 Pfam PF16260 Domain of unknown function (DUF4914) 11 621 2.3E-299 T 09-03-2017 IPR032583 Protein of unknown function DUF4914 L21SP3_RS08675 a1ad0d3f578b9a71a17cf785e3b90e80 626 SUPERFAMILY SSF53795 233 276 2.79E-32 T 09-03-2017 L21SP3_RS08675 a1ad0d3f578b9a71a17cf785e3b90e80 626 SUPERFAMILY SSF53795 305 607 2.79E-32 T 09-03-2017 L21SP3_RS04175 ec5eb55a03b84be69484001440c325fb 532 Gene3D G3DSA:3.40.50.200 86 330 6.8E-20 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 L21SP3_RS04175 ec5eb55a03b84be69484001440c325fb 532 Pfam PF00082 Subtilase family 89 299 6.7E-11 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 L21SP3_RS04175 ec5eb55a03b84be69484001440c325fb 532 SUPERFAMILY SSF52743 82 334 8.25E-19 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 L21SP3_RS04175 ec5eb55a03b84be69484001440c325fb 532 ProSitePatterns PS00018 EF-hand calcium-binding domain. 481 493 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS08040 403509b909efd845c7d80fee610beca9 344 SUPERFAMILY SSF51735 305 341 1.9E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS08040 403509b909efd845c7d80fee610beca9 344 SUPERFAMILY SSF51735 8 277 1.9E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS08040 403509b909efd845c7d80fee610beca9 344 Pfam PF01073 3-beta hydroxysteroid dehydrogenase/isomerase family 11 219 2.7E-26 T 09-03-2017 IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase GO:0003854|GO:0006694|GO:0016616|GO:0055114 L21SP3_RS08040 403509b909efd845c7d80fee610beca9 344 Gene3D G3DSA:3.40.50.720 8 334 2.1E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS05020 6dd7792fa26d83ee9d5277d2128559f5 122 Pfam PF01740 STAS domain 26 111 1.0E-13 T 09-03-2017 IPR002645 STAS domain L21SP3_RS05020 6dd7792fa26d83ee9d5277d2128559f5 122 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 28 110 2.2E-16 T 09-03-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 L21SP3_RS05020 6dd7792fa26d83ee9d5277d2128559f5 122 Gene3D G3DSA:3.30.750.24 19 112 1.1E-21 T 09-03-2017 IPR002645 STAS domain L21SP3_RS05020 6dd7792fa26d83ee9d5277d2128559f5 122 SUPERFAMILY SSF52091 23 112 1.45E-18 T 09-03-2017 IPR002645 STAS domain L21SP3_RS02005 84dd1ed31ec7211c8575614a4367d6ce 258 SUPERFAMILY SSF56300 2 257 7.6E-47 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS02005 84dd1ed31ec7211c8575614a4367d6ce 258 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 219 2.6E-23 T 09-03-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 L21SP3_RS02005 84dd1ed31ec7211c8575614a4367d6ce 258 Gene3D G3DSA:3.60.21.10 2 258 5.2E-66 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS02005 84dd1ed31ec7211c8575614a4367d6ce 258 PIRSF PIRSF000883 1 258 1.9E-51 T 09-03-2017 IPR011152 Phosphoesterase MJ0912 L21SP3_RS06775 3cf88e0c43ad2fdfd86ab6ab542c5573 263 SUPERFAMILY SSF54106 127 180 7.32E-5 T 09-03-2017 IPR018392 LysM domain L21SP3_RS06775 3cf88e0c43ad2fdfd86ab6ab542c5573 263 Gene3D G3DSA:3.10.350.10 127 180 2.0E-7 T 09-03-2017 IPR018392 LysM domain L21SP3_RS06775 3cf88e0c43ad2fdfd86ab6ab542c5573 263 Pfam PF01476 LysM domain 214 262 3.3E-9 T 09-03-2017 IPR018392 LysM domain L21SP3_RS06775 3cf88e0c43ad2fdfd86ab6ab542c5573 263 Pfam PF01476 LysM domain 129 180 1.0E-6 T 09-03-2017 IPR018392 LysM domain L21SP3_RS06775 3cf88e0c43ad2fdfd86ab6ab542c5573 263 Gene3D G3DSA:3.10.350.10 212 262 4.7E-10 T 09-03-2017 IPR018392 LysM domain L21SP3_RS06775 3cf88e0c43ad2fdfd86ab6ab542c5573 263 SMART SM00257 213 262 1.4E-5 T 09-03-2017 IPR018392 LysM domain L21SP3_RS06775 3cf88e0c43ad2fdfd86ab6ab542c5573 263 SMART SM00257 128 180 4.1E-7 T 09-03-2017 IPR018392 LysM domain L21SP3_RS06775 3cf88e0c43ad2fdfd86ab6ab542c5573 263 SUPERFAMILY SSF54106 212 262 2.88E-6 T 09-03-2017 IPR018392 LysM domain L21SP3_RS00565 5fb81e5dd01b4a53b4f1292eee2aa830 139 SUPERFAMILY SSF47226 28 130 5.1E-19 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 L21SP3_RS00565 5fb81e5dd01b4a53b4f1292eee2aa830 139 Gene3D G3DSA:1.20.120.160 37 129 2.2E-16 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 L21SP3_RS00565 5fb81e5dd01b4a53b4f1292eee2aa830 139 Pfam PF01627 Hpt domain 44 105 1.0E-10 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 L21SP3_RS11560 1421830d8aff36bbb3139479a0dec7fd 553 SUPERFAMILY SSF52540 31 224 4.42E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11560 1421830d8aff36bbb3139479a0dec7fd 553 SUPERFAMILY SSF48019 248 361 1.13E-11 T 09-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 L21SP3_RS11560 1421830d8aff36bbb3139479a0dec7fd 553 SMART SM00382 37 181 1.1E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS11560 1421830d8aff36bbb3139479a0dec7fd 553 Pfam PF13177 DNA polymerase III, delta subunit 20 180 6.7E-45 T 09-03-2017 L21SP3_RS11560 1421830d8aff36bbb3139479a0dec7fd 553 Gene3D G3DSA:3.40.50.300 15 168 2.2E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11560 1421830d8aff36bbb3139479a0dec7fd 553 Gene3D G3DSA:1.10.8.60 169 244 2.9E-26 T 09-03-2017 L21SP3_RS11560 1421830d8aff36bbb3139479a0dec7fd 553 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 360 7.6E-129 T 09-03-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 L21SP3_RS11560 1421830d8aff36bbb3139479a0dec7fd 553 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 239 375 5.8E-9 T 09-03-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 L21SP3_RS11560 1421830d8aff36bbb3139479a0dec7fd 553 Gene3D G3DSA:1.20.272.10 248 361 6.5E-9 T 09-03-2017 L21SP3_RS02010 83ad82e8c00487c45f9bb860318a72d4 230 SUPERFAMILY SSF103025 2 219 8.01E-25 T 09-03-2017 L21SP3_RS02010 83ad82e8c00487c45f9bb860318a72d4 230 Gene3D G3DSA:3.30.1360.120 3 53 2.3E-13 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 L21SP3_RS02010 83ad82e8c00487c45f9bb860318a72d4 230 Gene3D G3DSA:3.30.1360.120 131 218 2.3E-13 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 L21SP3_RS02010 83ad82e8c00487c45f9bb860318a72d4 230 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 217 7.2E-19 T 09-03-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal L21SP3_RS01495 78d4c3b8577f58c2544cfd67829db8d3 67 SMART SM00834 1 43 2.3E-15 T 09-03-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain L21SP3_RS01495 78d4c3b8577f58c2544cfd67829db8d3 67 Pfam PF09723 Zinc ribbon domain 1 42 1.1E-15 T 09-03-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain L21SP3_RS01495 78d4c3b8577f58c2544cfd67829db8d3 67 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 45 7.1E-17 T 09-03-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain L21SP3_RS03980 fa66d0019d54431ab342db5147573cbe 315 Pfam PF00326 Prolyl oligopeptidase family 229 289 1.4E-9 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 L21SP3_RS03980 fa66d0019d54431ab342db5147573cbe 315 SUPERFAMILY SSF53474 70 312 1.63E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS03980 fa66d0019d54431ab342db5147573cbe 315 Gene3D G3DSA:3.40.50.1820 64 311 8.5E-67 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS10210 7ddaa0325edccf9302e378fdf70ab6dd 208 SMART SM01018 1 84 1.6E-25 T 09-03-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 L21SP3_RS10210 7ddaa0325edccf9302e378fdf70ab6dd 208 Gene3D G3DSA:1.10.1240.10 5 74 1.6E-20 T 09-03-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 L21SP3_RS10210 7ddaa0325edccf9302e378fdf70ab6dd 208 SUPERFAMILY SSF52242 69 207 1.24E-44 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 L21SP3_RS10210 7ddaa0325edccf9302e378fdf70ab6dd 208 SUPERFAMILY SSF47644 3 81 3.27E-22 T 09-03-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 L21SP3_RS10210 7ddaa0325edccf9302e378fdf70ab6dd 208 Pfam PF02607 B12 binding domain 5 77 2.1E-18 T 09-03-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 L21SP3_RS10210 7ddaa0325edccf9302e378fdf70ab6dd 208 Gene3D G3DSA:3.40.50.280 75 207 3.5E-50 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 L21SP3_RS10210 7ddaa0325edccf9302e378fdf70ab6dd 208 Pfam PF02310 B12 binding domain 90 200 2.4E-25 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 L21SP3_RS10110 a20fe84136e5cbddb0603a1aa35465d3 407 Pfam PF01609 Transposase DDE domain 131 346 9.8E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS10110 a20fe84136e5cbddb0603a1aa35465d3 407 SUPERFAMILY SSF53098 128 375 2.2E-25 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS10110 a20fe84136e5cbddb0603a1aa35465d3 407 Gene3D G3DSA:3.90.350.10 255 322 2.9E-4 T 09-03-2017 IPR014736 Transposase, Tn5-like, core L21SP3_RS10110 a20fe84136e5cbddb0603a1aa35465d3 407 Pfam PF14294 Domain of unknown function (DUF4372) 7 73 1.4E-14 T 09-03-2017 IPR025399 Domain of unknown function DUF4372 L21SP3_RS03390 656fa86e0d395450167d177251b15500 347 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 215 239 3.0E-4 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS03390 656fa86e0d395450167d177251b15500 347 Gene3D G3DSA:3.90.550.10 1 130 3.8E-8 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS03390 656fa86e0d395450167d177251b15500 347 Gene3D G3DSA:2.160.10.10 187 343 5.6E-25 T 09-03-2017 L21SP3_RS03390 656fa86e0d395450167d177251b15500 347 SUPERFAMILY SSF53448 1 235 2.06E-11 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS03390 656fa86e0d395450167d177251b15500 347 SUPERFAMILY SSF51161 189 343 4.22E-24 T 09-03-2017 IPR011004 Trimeric LpxA-like L21SP3_RS06025 9dbe5e310e701e74d2f1faab24ee621f 224 Pfam PF00753 Metallo-beta-lactamase superfamily 11 171 5.1E-27 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS06025 9dbe5e310e701e74d2f1faab24ee621f 224 SMART SM00849 12 199 4.2E-38 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS06025 9dbe5e310e701e74d2f1faab24ee621f 224 SUPERFAMILY SSF56281 10 212 5.63E-46 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS06025 9dbe5e310e701e74d2f1faab24ee621f 224 Gene3D G3DSA:3.60.15.10 4 218 8.1E-50 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS10700 531f923746de96dcb7b8647f2e136bc1 283 Pfam PF13633 Prokaryotic N-terminal methylation site 21 46 2.1E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS10700 531f923746de96dcb7b8647f2e136bc1 283 PRINTS PR00813 Bacterial general secretion pathway protein G signature 22 47 1.0E-6 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS10700 531f923746de96dcb7b8647f2e136bc1 283 PRINTS PR00813 Bacterial general secretion pathway protein G signature 58 76 1.0E-6 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS10700 531f923746de96dcb7b8647f2e136bc1 283 Gene3D G3DSA:3.30.700.10 23 77 2.5E-6 T 09-03-2017 L21SP3_RS10700 531f923746de96dcb7b8647f2e136bc1 283 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 225 240 6.1E-5 T 09-03-2017 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP3_RS10700 531f923746de96dcb7b8647f2e136bc1 283 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 21 42 5.3E-6 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS10700 531f923746de96dcb7b8647f2e136bc1 283 SUPERFAMILY SSF54523 23 155 2.67E-16 T 09-03-2017 L21SP3_RS02745 6cab4720746bb879a942db90c3107f32 170 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 135 141 - T 09-03-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 L21SP3_RS02745 6cab4720746bb879a942db90c3107f32 170 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 86 165 4.1E-21 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 L21SP3_RS02745 6cab4720746bb879a942db90c3107f32 170 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 87 168 2.7E-22 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 L21SP3_RS02745 6cab4720746bb879a942db90c3107f32 170 SUPERFAMILY SSF46767 86 169 5.36E-21 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 L21SP3_RS02745 6cab4720746bb879a942db90c3107f32 170 Gene3D G3DSA:1.10.10.10 85 169 2.2E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS00125 9b4b3492eb5bdb7798d7a19530c29db5 263 SMART SM00028 70 103 0.0044 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS00125 9b4b3492eb5bdb7798d7a19530c29db5 263 Gene3D G3DSA:1.25.40.10 34 113 2.6E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00125 9b4b3492eb5bdb7798d7a19530c29db5 263 SUPERFAMILY SSF81901 34 109 3.4E-9 T 09-03-2017 L21SP3_RS06000 83ac31eeb44be7dd60066e06d467b6f2 301 Gene3D G3DSA:1.10.10.60 194 248 6.1E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS06000 83ac31eeb44be7dd60066e06d467b6f2 301 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 279 295 1.3E-5 T 09-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP3_RS06000 83ac31eeb44be7dd60066e06d467b6f2 301 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 264 279 1.3E-5 T 09-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 L21SP3_RS06000 83ac31eeb44be7dd60066e06d467b6f2 301 SUPERFAMILY SSF46689 248 296 1.06E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS06000 83ac31eeb44be7dd60066e06d467b6f2 301 SMART SM00342 212 295 8.8E-22 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS06000 83ac31eeb44be7dd60066e06d467b6f2 301 SUPERFAMILY SSF46689 197 246 4.32E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS06000 83ac31eeb44be7dd60066e06d467b6f2 301 Pfam PF02311 AraC-like ligand binding domain 43 96 1.6E-9 T 09-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP3_RS06000 83ac31eeb44be7dd60066e06d467b6f2 301 Gene3D G3DSA:1.10.10.60 249 297 2.7E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS06000 83ac31eeb44be7dd60066e06d467b6f2 301 Gene3D G3DSA:2.60.120.280 28 183 1.1E-13 T 09-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP3_RS06000 83ac31eeb44be7dd60066e06d467b6f2 301 SUPERFAMILY SSF51215 43 183 1.57E-13 T 09-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 L21SP3_RS06000 83ac31eeb44be7dd60066e06d467b6f2 301 Pfam PF12833 Helix-turn-helix domain 221 296 8.1E-19 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS01800 194d84e9061e553f12c6f0eaf7bbbbe2 152 Pfam PF00886 Ribosomal protein S16 9 69 1.6E-22 T 09-03-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS01800 194d84e9061e553f12c6f0eaf7bbbbe2 152 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 81 4.5E-28 T 09-03-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS01800 194d84e9061e553f12c6f0eaf7bbbbe2 152 Gene3D G3DSA:3.30.1320.10 2 81 3.4E-29 T 09-03-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS01800 194d84e9061e553f12c6f0eaf7bbbbe2 152 SUPERFAMILY SSF54565 2 88 5.76E-27 T 09-03-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS01800 194d84e9061e553f12c6f0eaf7bbbbe2 152 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 79 22.37 T 09-03-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02985 ac08e5e6b9ac0fa91cf0d2dd36fba752 591 Pfam PF00117 Glutamine amidotransferase class-I 341 565 6.5E-47 T 09-03-2017 IPR017926 Glutamine amidotransferase L21SP3_RS02985 ac08e5e6b9ac0fa91cf0d2dd36fba752 591 SUPERFAMILY SSF52317 328 571 3.52E-67 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS02985 ac08e5e6b9ac0fa91cf0d2dd36fba752 591 Gene3D G3DSA:3.40.50.880 327 571 3.9E-89 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS02985 ac08e5e6b9ac0fa91cf0d2dd36fba752 591 Gene3D G3DSA:3.40.50.300 31 317 2.9E-101 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02985 ac08e5e6b9ac0fa91cf0d2dd36fba752 591 TIGRFAM TIGR00337 PyrG: CTP synthase 34 567 9.9E-196 T 09-03-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 L21SP3_RS02985 ac08e5e6b9ac0fa91cf0d2dd36fba752 591 Pfam PF06418 CTP synthase N-terminus 35 298 4.5E-95 T 09-03-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 L21SP3_RS02985 ac08e5e6b9ac0fa91cf0d2dd36fba752 591 SUPERFAMILY SSF52540 34 299 2.66E-89 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11295 668596454778da08c7428d71ca5062ce 653 Pfam PF00005 ABC transporter 21 191 4.4E-24 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS11295 668596454778da08c7428d71ca5062ce 653 Pfam PF00005 ABC transporter 347 476 1.4E-22 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS11295 668596454778da08c7428d71ca5062ce 653 SUPERFAMILY SSF52540 4 234 1.97E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11295 668596454778da08c7428d71ca5062ce 653 Gene3D G3DSA:3.40.50.300 329 560 2.1E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11295 668596454778da08c7428d71ca5062ce 653 SUPERFAMILY SSF52540 314 549 2.55E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11295 668596454778da08c7428d71ca5062ce 653 SMART SM00382 355 520 2.0E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS11295 668596454778da08c7428d71ca5062ce 653 SMART SM00382 28 236 2.3E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS11295 668596454778da08c7428d71ca5062ce 653 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS11295 668596454778da08c7428d71ca5062ce 653 Gene3D G3DSA:3.40.50.300 4 106 5.8E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11295 668596454778da08c7428d71ca5062ce 653 Gene3D G3DSA:3.40.50.300 139 281 5.8E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11295 668596454778da08c7428d71ca5062ce 653 Pfam PF12848 ABC transporter 230 303 8.4E-16 T 09-03-2017 IPR032781 ABC-transporter extension domain L21SP3_RS11295 668596454778da08c7428d71ca5062ce 653 ProSitePatterns PS00211 ABC transporters family signature. 448 462 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS06545 c7ae1306c8c0e7414f66631657d3d03b 177 Gene3D G3DSA:3.40.50.1000 2 172 4.7E-42 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS06545 c7ae1306c8c0e7414f66631657d3d03b 177 PIRSF PIRSF006118 3 176 8.0E-58 T 09-03-2017 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 L21SP3_RS06545 c7ae1306c8c0e7414f66631657d3d03b 177 Pfam PF08282 haloacid dehalogenase-like hydrolase 94 147 4.5E-7 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS06545 c7ae1306c8c0e7414f66631657d3d03b 177 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 14 166 2.8E-49 T 09-03-2017 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 L21SP3_RS06545 c7ae1306c8c0e7414f66631657d3d03b 177 SUPERFAMILY SSF56784 10 172 2.07E-40 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS06530 8a24cc7eb5a996fc1613277ec2580298 219 SUPERFAMILY SSF51306 99 216 2.09E-29 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C L21SP3_RS06530 8a24cc7eb5a996fc1613277ec2580298 219 TIGRFAM TIGR00498 lexA: repressor LexA 12 219 1.1E-42 T 09-03-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 L21SP3_RS06530 8a24cc7eb5a996fc1613277ec2580298 219 Pfam PF00717 Peptidase S24-like 136 203 1.1E-15 T 09-03-2017 IPR019759 Peptidase S24/S26A/S26B L21SP3_RS06530 8a24cc7eb5a996fc1613277ec2580298 219 Gene3D G3DSA:2.10.109.10 99 218 3.0E-36 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain L21SP3_RS06530 8a24cc7eb5a996fc1613277ec2580298 219 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 133 143 9.2E-5 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 L21SP3_RS06530 8a24cc7eb5a996fc1613277ec2580298 219 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 173 185 9.2E-5 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 L21SP3_RS06530 8a24cc7eb5a996fc1613277ec2580298 219 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 144 155 9.2E-5 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 L21SP3_RS06530 8a24cc7eb5a996fc1613277ec2580298 219 Gene3D G3DSA:1.10.10.10 11 77 1.5E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS06530 8a24cc7eb5a996fc1613277ec2580298 219 Pfam PF01726 LexA DNA binding domain 12 72 6.3E-8 T 09-03-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 L21SP3_RS06530 8a24cc7eb5a996fc1613277ec2580298 219 SUPERFAMILY SSF46785 11 77 3.25E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS09970 3df6f0da22c233cb0d6de8ae675e1f7a 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 4.4E-27 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS09970 3df6f0da22c233cb0d6de8ae675e1f7a 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 205 229 4.4E-27 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS09970 3df6f0da22c233cb0d6de8ae675e1f7a 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 174 195 4.4E-27 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS09970 3df6f0da22c233cb0d6de8ae675e1f7a 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 58 74 4.4E-27 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS09970 3df6f0da22c233cb0d6de8ae675e1f7a 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 36 56 4.4E-27 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS09970 3df6f0da22c233cb0d6de8ae675e1f7a 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 4.4E-27 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS09970 3df6f0da22c233cb0d6de8ae675e1f7a 264 Pfam PF00459 Inositol monophosphatase family 5 241 4.0E-44 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 L21SP3_RS09970 3df6f0da22c233cb0d6de8ae675e1f7a 264 Gene3D G3DSA:3.40.190.80 176 262 1.0E-19 T 09-03-2017 L21SP3_RS09970 3df6f0da22c233cb0d6de8ae675e1f7a 264 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 09-03-2017 IPR020583 Inositol monophosphatase, metal-binding site L21SP3_RS09970 3df6f0da22c233cb0d6de8ae675e1f7a 264 SUPERFAMILY SSF56655 3 262 2.49E-62 T 09-03-2017 L21SP3_RS09970 3df6f0da22c233cb0d6de8ae675e1f7a 264 Gene3D G3DSA:3.30.540.10 2 158 4.6E-37 T 09-03-2017 L21SP3_RS01605 c6e7eaca33fcb02f17d791c6fc64ad95 511 ProSitePatterns PS00523 Sulfatases signature 1. 79 91 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS01605 c6e7eaca33fcb02f17d791c6fc64ad95 511 Pfam PF16385 Domain of unknown function 407 500 4.6E-23 T 09-03-2017 IPR032158 Domain of unknown function DUF4994 L21SP3_RS01605 c6e7eaca33fcb02f17d791c6fc64ad95 511 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 2 22 3.6E-5 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal L21SP3_RS01605 c6e7eaca33fcb02f17d791c6fc64ad95 511 Gene3D G3DSA:3.40.720.10 227 418 1.8E-103 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS01605 c6e7eaca33fcb02f17d791c6fc64ad95 511 Gene3D G3DSA:3.40.720.10 30 189 1.8E-103 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS01605 c6e7eaca33fcb02f17d791c6fc64ad95 511 SUPERFAMILY SSF53649 30 505 1.45E-118 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS01605 c6e7eaca33fcb02f17d791c6fc64ad95 511 Gene3D G3DSA:3.30.1120.10 419 504 6.2E-15 T 09-03-2017 L21SP3_RS01605 c6e7eaca33fcb02f17d791c6fc64ad95 511 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 22 2.7E-4 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal L21SP3_RS01605 c6e7eaca33fcb02f17d791c6fc64ad95 511 ProSitePatterns PS00149 Sulfatases signature 2. 126 136 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS01605 c6e7eaca33fcb02f17d791c6fc64ad95 511 Pfam PF00884 Sulfatase 33 399 1.1E-59 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS06255 646cb820b6af73855aa5031ea9c09cbf 284 Pfam PF00149 Calcineurin-like phosphoesterase 37 234 3.0E-6 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 L21SP3_RS06255 646cb820b6af73855aa5031ea9c09cbf 284 SUPERFAMILY SSF56300 25 248 1.12E-16 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS06255 646cb820b6af73855aa5031ea9c09cbf 284 Gene3D G3DSA:3.60.21.10 8 271 4.0E-17 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS09930 e2f0254cb4975f6cfe86c1e63596f51c 273 SUPERFAMILY SSF56317 7 252 1.96E-43 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP3_RS09930 e2f0254cb4975f6cfe86c1e63596f51c 273 Gene3D G3DSA:3.60.110.10 10 251 2.2E-41 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP3_RS09930 e2f0254cb4975f6cfe86c1e63596f51c 273 Pfam PF00795 Carbon-nitrogen hydrolase 12 251 1.1E-31 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 L21SP3_RS11055 5630851aa60c125e4ce7023b6a09a946 255 Pfam PF00005 ABC transporter 25 179 7.6E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS11055 5630851aa60c125e4ce7023b6a09a946 255 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 9 255 1.3E-120 T 09-03-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 L21SP3_RS11055 5630851aa60c125e4ce7023b6a09a946 255 SUPERFAMILY SSF52540 6 242 2.48E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11055 5630851aa60c125e4ce7023b6a09a946 255 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS11055 5630851aa60c125e4ce7023b6a09a946 255 Gene3D G3DSA:3.40.50.300 3 247 9.7E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11055 5630851aa60c125e4ce7023b6a09a946 255 SMART SM00382 33 235 5.1E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS01695 aabf5d836eaa0921270a5bb41b7e1968 195 SMART SM00935 6 191 5.3E-13 T 09-03-2017 IPR005632 Chaperone protein Skp GO:0051082 L21SP3_RS01695 aabf5d836eaa0921270a5bb41b7e1968 195 Gene3D G3DSA:3.30.910.20 109 190 2.2E-9 T 09-03-2017 L21SP3_RS01695 aabf5d836eaa0921270a5bb41b7e1968 195 Gene3D G3DSA:3.30.910.20 34 73 2.2E-9 T 09-03-2017 L21SP3_RS01695 aabf5d836eaa0921270a5bb41b7e1968 195 SUPERFAMILY SSF111384 33 191 2.62E-15 T 09-03-2017 IPR024930 Skp domain L21SP3_RS01695 aabf5d836eaa0921270a5bb41b7e1968 195 Pfam PF03938 Outer membrane protein (OmpH-like) 19 190 1.1E-18 T 09-03-2017 IPR005632 Chaperone protein Skp GO:0051082 L21SP3_RS01400 777f918e4ca845a9f5014f173e4cbaff 165 Pfam PF04093 rod shape-determining protein MreD 2 149 1.5E-6 T 09-03-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 L21SP3_RS01400 777f918e4ca845a9f5014f173e4cbaff 165 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 2 151 3.6E-12 T 09-03-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 L21SP3_RS00750 73eb6363b98059f0e7d55c6c4c971417 455 Pfam PF05598 Transposase domain (DUF772) 55 123 1.5E-14 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS00750 73eb6363b98059f0e7d55c6c4c971417 455 Pfam PF13751 Transposase DDE domain 384 447 3.8E-14 T 09-03-2017 IPR025668 Transposase DDE domain L21SP3_RS08300 73eb6363b98059f0e7d55c6c4c971417 455 Pfam PF05598 Transposase domain (DUF772) 55 123 1.5E-14 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS08300 73eb6363b98059f0e7d55c6c4c971417 455 Pfam PF13751 Transposase DDE domain 384 447 3.8E-14 T 09-03-2017 IPR025668 Transposase DDE domain L21SP3_RS09700 73eb6363b98059f0e7d55c6c4c971417 455 Pfam PF05598 Transposase domain (DUF772) 55 123 1.5E-14 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS09700 73eb6363b98059f0e7d55c6c4c971417 455 Pfam PF13751 Transposase DDE domain 384 447 3.8E-14 T 09-03-2017 IPR025668 Transposase DDE domain L21SP3_RS03935 73eb6363b98059f0e7d55c6c4c971417 455 Pfam PF05598 Transposase domain (DUF772) 55 123 1.5E-14 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS03935 73eb6363b98059f0e7d55c6c4c971417 455 Pfam PF13751 Transposase DDE domain 384 447 3.8E-14 T 09-03-2017 IPR025668 Transposase DDE domain L21SP3_RS05540 3b83ee06b31e33115bc3b13072f96197 351 SUPERFAMILY SSF51126 53 337 4.19E-18 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS05540 3b83ee06b31e33115bc3b13072f96197 351 SMART SM00710 67 87 5800.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS05540 3b83ee06b31e33115bc3b13072f96197 351 SMART SM00710 298 320 650.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS05540 3b83ee06b31e33115bc3b13072f96197 351 SMART SM00710 171 193 1.1 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS05540 3b83ee06b31e33115bc3b13072f96197 351 SMART SM00710 194 214 2400.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS05540 3b83ee06b31e33115bc3b13072f96197 351 SMART SM00710 256 278 2.9 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS05540 3b83ee06b31e33115bc3b13072f96197 351 SMART SM00710 117 156 1600.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS05540 3b83ee06b31e33115bc3b13072f96197 351 Gene3D G3DSA:2.160.20.10 82 335 2.3E-9 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS05540 3b83ee06b31e33115bc3b13072f96197 351 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 255 291 7.8E-6 T 09-03-2017 IPR022441 Parallel beta-helix repeat-2 L21SP3_RS05540 3b83ee06b31e33115bc3b13072f96197 351 Pfam PF13229 Right handed beta helix region 62 221 1.7E-10 T 09-03-2017 L21SP3_RS01455 3ec54c2f8185bc4a6fa4b1cddaf9d761 442 Pfam PF04317 YcjX-like family, DUF463 11 440 4.3E-36 T 09-03-2017 IPR007413 Protein of unknown function DUF463, YcjX-like protein L21SP3_RS01455 3ec54c2f8185bc4a6fa4b1cddaf9d761 442 Gene3D G3DSA:3.40.50.150 205 321 8.6E-4 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS10400 aed8f2ab981d5c70cb387193b548ee43 352 SUPERFAMILY SSF53187 4 82 1.11E-60 T 09-03-2017 L21SP3_RS10400 aed8f2ab981d5c70cb387193b548ee43 352 SUPERFAMILY SSF53187 172 342 1.11E-60 T 09-03-2017 L21SP3_RS10400 aed8f2ab981d5c70cb387193b548ee43 352 SUPERFAMILY SSF101821 70 177 9.92E-28 T 09-03-2017 L21SP3_RS10400 aed8f2ab981d5c70cb387193b548ee43 352 Pfam PF05343 M42 glutamyl aminopeptidase 46 336 1.7E-89 T 09-03-2017 IPR008007 Peptidase M42 L21SP3_RS10400 aed8f2ab981d5c70cb387193b548ee43 352 Gene3D G3DSA:3.40.630.10 3 71 1.8E-75 T 09-03-2017 L21SP3_RS10400 aed8f2ab981d5c70cb387193b548ee43 352 Gene3D G3DSA:3.40.630.10 166 343 1.8E-75 T 09-03-2017 L21SP3_RS10400 aed8f2ab981d5c70cb387193b548ee43 352 Gene3D G3DSA:2.40.30.40 72 159 3.1E-32 T 09-03-2017 IPR023367 Peptidase M42, domain 2 L21SP3_RS10400 aed8f2ab981d5c70cb387193b548ee43 352 PIRSF PIRSF001123 2 349 2.9E-100 T 09-03-2017 IPR008007 Peptidase M42 L21SP3_RS09050 bf1eb1ba08d74a8879e6868196557937 311 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 9 293 5.3E-36 T 09-03-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD L21SP3_RS09050 bf1eb1ba08d74a8879e6868196557937 311 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 13 306 3.5E-16 T 09-03-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD L21SP3_RS09550 ea4f84b7f9553fca4578225bac89c739 219 Pfam PF07589 PEP-CTERM motif 198 218 3.3E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS09550 ea4f84b7f9553fca4578225bac89c739 219 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 198 218 9.8E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS05105 0bd0516ece7be9f1c5ae0d00e77a9676 117 Pfam PF13683 Integrase core domain 22 87 9.9E-22 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS05105 0bd0516ece7be9f1c5ae0d00e77a9676 117 Gene3D G3DSA:3.30.420.10 1 87 2.9E-22 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS05105 0bd0516ece7be9f1c5ae0d00e77a9676 117 SUPERFAMILY SSF53098 1 99 1.64E-23 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS08155 e2a5afb9aa5a050a3830a59d8a8d5ca0 319 Hamap MF_00361 NAD kinase [nadK]. 39 309 27.285 T 09-03-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 L21SP3_RS08155 e2a5afb9aa5a050a3830a59d8a8d5ca0 319 Gene3D G3DSA:2.60.200.30 165 285 2.9E-39 T 09-03-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 L21SP3_RS08155 e2a5afb9aa5a050a3830a59d8a8d5ca0 319 Gene3D G3DSA:3.40.50.10330 69 164 2.8E-26 T 09-03-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 L21SP3_RS08155 e2a5afb9aa5a050a3830a59d8a8d5ca0 319 SUPERFAMILY SSF111331 72 311 2.88E-71 T 09-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain L21SP3_RS08155 e2a5afb9aa5a050a3830a59d8a8d5ca0 319 Pfam PF01513 ATP-NAD kinase 83 292 5.2E-51 T 09-03-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 L21SP3_RS02385 f0c897b51dea6d083ab3a28a55156456 593 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 71 2.3E-11 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS02385 f0c897b51dea6d083ab3a28a55156456 593 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 87 206 2.0E-42 T 09-03-2017 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS02385 f0c897b51dea6d083ab3a28a55156456 593 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 215 438 1.3E-91 T 09-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS02385 f0c897b51dea6d083ab3a28a55156456 593 Gene3D G3DSA:1.10.1140.10 449 554 8.2E-19 T 09-03-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS02385 f0c897b51dea6d083ab3a28a55156456 593 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 429 438 - T 09-03-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS02385 f0c897b51dea6d083ab3a28a55156456 593 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 4 590 48.423 T 09-03-2017 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS02385 f0c897b51dea6d083ab3a28a55156456 593 SUPERFAMILY SSF52540 187 442 3.84E-77 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02385 f0c897b51dea6d083ab3a28a55156456 593 SUPERFAMILY SSF50615 5 74 2.75E-13 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS02385 f0c897b51dea6d083ab3a28a55156456 593 SUPERFAMILY SSF47917 452 559 8.11E-20 T 09-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 L21SP3_RS02385 f0c897b51dea6d083ab3a28a55156456 593 Gene3D G3DSA:3.40.50.300 166 438 4.9E-97 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05165 85172cd1acc3d2ea262fccf64ef5735f 705 SUPERFAMILY SSF55931 440 582 5.49E-74 T 09-03-2017 L21SP3_RS05165 85172cd1acc3d2ea262fccf64ef5735f 705 SUPERFAMILY SSF55931 164 397 5.49E-74 T 09-03-2017 L21SP3_RS05165 85172cd1acc3d2ea262fccf64ef5735f 705 SMART SM01230 173 458 1.9E-41 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 L21SP3_RS05165 85172cd1acc3d2ea262fccf64ef5735f 705 Pfam PF12437 Glutamine synthetase type III N terminal 10 172 3.6E-77 T 09-03-2017 IPR022147 Glutamine synthetase type III N-terminal GO:0004356 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 L21SP3_RS05165 85172cd1acc3d2ea262fccf64ef5735f 705 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 318 333 - T 09-03-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 L21SP3_RS05165 85172cd1acc3d2ea262fccf64ef5735f 705 Pfam PF00120 Glutamine synthetase, catalytic domain 191 351 4.0E-19 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 L21SP3_RS05165 85172cd1acc3d2ea262fccf64ef5735f 705 Gene3D G3DSA:3.30.590.10 440 581 1.8E-85 T 09-03-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 L21SP3_RS05165 85172cd1acc3d2ea262fccf64ef5735f 705 Gene3D G3DSA:3.30.590.10 182 397 1.8E-85 T 09-03-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 L21SP3_RS00215 9e992b093cea99198f0986c99cdfb60b 749 Gene3D G3DSA:2.60.40.10 328 421 1.1E-9 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS00215 9e992b093cea99198f0986c99cdfb60b 749 Gene3D G3DSA:2.60.40.10 444 503 9.2E-5 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS00215 9e992b093cea99198f0986c99cdfb60b 749 SUPERFAMILY SSF48726 427 506 5.19E-6 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS00215 9e992b093cea99198f0986c99cdfb60b 749 SMART SM00409 335 421 8.2E-7 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS00215 9e992b093cea99198f0986c99cdfb60b 749 SMART SM00409 425 511 1.6 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS00215 9e992b093cea99198f0986c99cdfb60b 749 Gene3D G3DSA:2.60.120.200 507 698 1.1E-22 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00215 9e992b093cea99198f0986c99cdfb60b 749 SUPERFAMILY SSF49899 513 700 4.33E-23 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00215 9e992b093cea99198f0986c99cdfb60b 749 SUPERFAMILY SSF48726 327 420 1.81E-10 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS00215 9e992b093cea99198f0986c99cdfb60b 749 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 569 694 4.7E-17 T 09-03-2017 L21SP3_RS06090 8df35b926808e969c4dcda0345e1e8be 127 Gene3D G3DSA:4.10.910.10 74 122 7.1E-24 T 09-03-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06090 8df35b926808e969c4dcda0345e1e8be 127 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 09-03-2017 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06090 8df35b926808e969c4dcda0345e1e8be 127 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 26.775 T 09-03-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06090 8df35b926808e969c4dcda0345e1e8be 127 Pfam PF00416 Ribosomal protein S13/S18 3 109 3.8E-30 T 09-03-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06090 8df35b926808e969c4dcda0345e1e8be 127 PIRSF PIRSF002134 1 125 1.2E-44 T 09-03-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06090 8df35b926808e969c4dcda0345e1e8be 127 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.7E-45 T 09-03-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06090 8df35b926808e969c4dcda0345e1e8be 127 SUPERFAMILY SSF46946 3 121 3.79E-42 T 09-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 L21SP3_RS06090 8df35b926808e969c4dcda0345e1e8be 127 Gene3D G3DSA:1.10.8.50 1 72 1.2E-25 T 09-03-2017 L21SP3_RS05555 18238d9ac99cfabcf8620ae926b6e6e0 162 SUPERFAMILY SSF52096 44 98 6.36E-6 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS05555 18238d9ac99cfabcf8620ae926b6e6e0 162 Pfam PF01343 Peptidase family S49 1 111 4.6E-15 T 09-03-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 L21SP3_RS05555 18238d9ac99cfabcf8620ae926b6e6e0 162 Gene3D G3DSA:3.90.226.10 56 114 7.5E-12 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS05555 18238d9ac99cfabcf8620ae926b6e6e0 162 Gene3D G3DSA:3.40.1750.10 2 55 2.1E-5 T 09-03-2017 L21SP3_RS07765 0828edac189a57097aff20d624323408 236 SMART SM00028 128 161 19.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS07765 0828edac189a57097aff20d624323408 236 SMART SM00028 162 195 2.4 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS07765 0828edac189a57097aff20d624323408 236 SMART SM00028 60 93 5.5 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 L21SP3_RS07765 0828edac189a57097aff20d624323408 236 SUPERFAMILY SSF48452 49 197 8.34E-15 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS07765 0828edac189a57097aff20d624323408 236 Gene3D G3DSA:1.25.40.10 47 204 1.9E-19 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS01060 01b0a35d5598547d2d5784483dbdb725 735 Gene3D G3DSA:1.25.10.10 41 198 9.1E-6 T 09-03-2017 IPR011989 Armadillo-like helical L21SP3_RS01060 01b0a35d5598547d2d5784483dbdb725 735 SUPERFAMILY SSF48371 602 664 5.76E-20 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 L21SP3_RS01060 01b0a35d5598547d2d5784483dbdb725 735 SUPERFAMILY SSF48371 38 573 5.76E-20 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 L21SP3_RS01060 01b0a35d5598547d2d5784483dbdb725 735 Gene3D G3DSA:1.25.10.10 376 492 1.1E-7 T 09-03-2017 IPR011989 Armadillo-like helical L21SP3_RS01060 01b0a35d5598547d2d5784483dbdb725 735 Gene3D G3DSA:1.25.10.10 294 339 1.1E-7 T 09-03-2017 IPR011989 Armadillo-like helical L21SP3_RS04615 0c6e055f1f21ecc1b916394eaec2b883 94 Gene3D G3DSA:3.30.70.330 3 89 9.4E-33 T 09-03-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 L21SP3_RS04615 0c6e055f1f21ecc1b916394eaec2b883 94 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 5 75 1.4E-24 T 09-03-2017 IPR000504 RNA recognition motif domain GO:0003676 L21SP3_RS04615 0c6e055f1f21ecc1b916394eaec2b883 94 SMART SM00360 4 77 1.4E-29 T 09-03-2017 IPR000504 RNA recognition motif domain GO:0003676 L21SP3_RS04615 0c6e055f1f21ecc1b916394eaec2b883 94 SUPERFAMILY SSF54928 3 91 1.01E-33 T 09-03-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 L21SP3_RS07375 d24cb4ecb1911633436028e8dd6e34aa 287 Gene3D G3DSA:3.40.50.1980 192 284 2.3E-7 T 09-03-2017 L21SP3_RS07375 d24cb4ecb1911633436028e8dd6e34aa 287 Gene3D G3DSA:3.40.50.1980 23 106 5.4E-5 T 09-03-2017 L21SP3_RS07375 d24cb4ecb1911633436028e8dd6e34aa 287 Pfam PF01297 Zinc-uptake complex component A periplasmic 52 283 2.6E-16 T 09-03-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 L21SP3_RS07375 d24cb4ecb1911633436028e8dd6e34aa 287 SUPERFAMILY SSF53807 37 283 1.86E-24 T 09-03-2017 L21SP3_RS11225 47716c8d9bb4293ede82e1e50c96ef5f 538 Pfam PF06439 Domain of Unknown Function (DUF1080) 401 536 3.0E-11 T 09-03-2017 IPR010496 Domain of unknown function DUF1080 L21SP3_RS11225 47716c8d9bb4293ede82e1e50c96ef5f 538 Pfam PF04616 Glycosyl hydrolases family 43 33 330 1.8E-47 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS11225 47716c8d9bb4293ede82e1e50c96ef5f 538 Gene3D G3DSA:2.115.10.20 29 347 7.2E-76 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS11225 47716c8d9bb4293ede82e1e50c96ef5f 538 SUPERFAMILY SSF75005 30 348 1.18E-56 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS00755 0263b79f909db02a9388049d5257a0e5 698 Gene3D G3DSA:2.60.120.200 422 639 3.2E-26 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00755 0263b79f909db02a9388049d5257a0e5 698 SMART SM00408 341 409 8.5E-5 T 09-03-2017 IPR003598 Immunoglobulin subtype 2 L21SP3_RS00755 0263b79f909db02a9388049d5257a0e5 698 SMART SM00409 335 421 1.2E-12 T 09-03-2017 IPR003599 Immunoglobulin subtype L21SP3_RS00755 0263b79f909db02a9388049d5257a0e5 698 Pfam PF13927 Immunoglobulin domain 329 406 2.1E-13 T 09-03-2017 L21SP3_RS00755 0263b79f909db02a9388049d5257a0e5 698 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 491 636 3.9E-21 T 09-03-2017 L21SP3_RS00755 0263b79f909db02a9388049d5257a0e5 698 Gene3D G3DSA:2.60.40.10 329 421 6.2E-16 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS00755 0263b79f909db02a9388049d5257a0e5 698 SUPERFAMILY SSF49899 418 640 3.27E-26 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00755 0263b79f909db02a9388049d5257a0e5 698 SUPERFAMILY SSF48726 329 421 1.7E-17 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS07125 90c94c5ad2f8c3704e12d25b91a9463f 65 Gene3D G3DSA:3.40.1620.10 5 29 5.4E-6 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM L21SP3_RS07125 90c94c5ad2f8c3704e12d25b91a9463f 65 SUPERFAMILY SSF143120 5 46 5.67E-6 T 09-03-2017 L21SP3_RS07125 90c94c5ad2f8c3704e12d25b91a9463f 65 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 47 7.2E-7 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM L21SP3_RS02690 9ce8d3d4d04dcb6da5522d1ed47f437e 422 Pfam PF01609 Transposase DDE domain 275 412 3.9E-7 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS02690 9ce8d3d4d04dcb6da5522d1ed47f437e 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.6E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS03300 ea80fdffca2adf6530659f525ee3746d 697 Pfam PF14323 GxGYxYP putative glycoside hydrolase C-terminal domain 453 692 6.6E-47 T 09-03-2017 IPR025832 GxGYxYP putative glycoside hydrolase, C-terminal L21SP3_RS03300 ea80fdffca2adf6530659f525ee3746d 697 Pfam PF16216 GxGYxY sequence motif in domain of unknown function N-terminal 216 428 5.7E-34 T 09-03-2017 IPR032626 GxGYxYP putative glycoside hydrolase, N-terminal L21SP3_RS04595 b3e63df1f281af363b114dd3ff7386c2 391 SUPERFAMILY SSF49899 14 253 2.24E-23 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04595 b3e63df1f281af363b114dd3ff7386c2 391 Gene3D G3DSA:2.60.120.200 88 253 1.4E-17 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04595 b3e63df1f281af363b114dd3ff7386c2 391 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 104 253 1.2E-11 T 09-03-2017 L21SP3_RS09900 620d593ef45d50ec15b37d17ec51698f 745 Gene3D G3DSA:1.25.40.10 574 698 1.7E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS09900 620d593ef45d50ec15b37d17ec51698f 745 SUPERFAMILY SSF48452 604 699 2.81E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS09900 620d593ef45d50ec15b37d17ec51698f 745 Pfam PF04932 O-Antigen ligase 245 382 5.0E-7 T 09-03-2017 IPR007016 O-antigen ligase-related L21SP3_RS03230 d0b980c5ef591432d2cbc196b6b05f75 282 Pfam PF01026 TatD related DNase 30 280 2.9E-75 T 09-03-2017 IPR001130 TatD family GO:0016788 L21SP3_RS03230 d0b980c5ef591432d2cbc196b6b05f75 282 PIRSF PIRSF005902 3 282 1.9E-80 T 09-03-2017 IPR001130 TatD family GO:0016788 L21SP3_RS03230 d0b980c5ef591432d2cbc196b6b05f75 282 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 29 281 1.2E-80 T 09-03-2017 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 L21SP3_RS03230 d0b980c5ef591432d2cbc196b6b05f75 282 SUPERFAMILY SSF51556 26 282 3.86E-84 T 09-03-2017 IPR032466 Metal-dependent hydrolase L21SP3_RS03230 d0b980c5ef591432d2cbc196b6b05f75 282 Gene3D G3DSA:3.20.20.140 24 282 7.7E-91 T 09-03-2017 L21SP3_RS03230 d0b980c5ef591432d2cbc196b6b05f75 282 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 151 161 - T 09-03-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 SUPERFAMILY SSF49452 21 104 2.55E-14 T 09-03-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 Gene3D G3DSA:2.60.40.1120 27 105 5.8E-17 T 09-03-2017 IPR014766 Carboxypeptidase, regulatory domain L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 Pfam PF07715 TonB-dependent Receptor Plug Domain 135 234 7.0E-9 T 09-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 Pfam PF13620 Carboxypeptidase regulatory-like domain 27 104 1.9E-15 T 09-03-2017 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 Gene3D G3DSA:2.170.130.10 134 234 1.3E-13 T 09-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 Gene3D G3DSA:2.40.170.20 458 512 2.5E-50 T 09-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 Gene3D G3DSA:2.40.170.20 235 243 2.5E-50 T 09-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 Gene3D G3DSA:2.40.170.20 556 1021 2.5E-50 T 09-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 Gene3D G3DSA:2.40.170.20 300 424 2.5E-50 T 09-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 Pfam PF00593 TonB dependent receptor 740 1017 7.7E-27 T 09-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 SUPERFAMILY SSF56935 470 530 3.92E-78 T 09-03-2017 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 SUPERFAMILY SSF56935 737 1021 3.92E-78 T 09-03-2017 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 SUPERFAMILY SSF56935 133 257 3.92E-78 T 09-03-2017 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 SUPERFAMILY SSF56935 387 434 3.92E-78 T 09-03-2017 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 SUPERFAMILY SSF56935 297 346 3.92E-78 T 09-03-2017 L21SP3_RS07630 6eba2e20ea2d4d5e5c3ce3793d52a77b 1021 SUPERFAMILY SSF56935 583 698 3.92E-78 T 09-03-2017 L21SP3_RS10205 c9fc9a407305ecceb6087fe776c805d4 251 Gene3D G3DSA:3.30.2010.10 71 144 2.4E-14 T 09-03-2017 L21SP3_RS10205 c9fc9a407305ecceb6087fe776c805d4 251 Pfam PF01435 Peptidase family M48 84 238 6.5E-26 T 09-03-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 L21SP3_RS02085 102c843c7454713fd0ecdb17adfc139b 164 SUPERFAMILY SSF50249 3 164 3.77E-49 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS02085 102c843c7454713fd0ecdb17adfc139b 164 Gene3D G3DSA:2.40.50.140 1 164 1.6E-40 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS02085 102c843c7454713fd0ecdb17adfc139b 164 Hamap MF_00984 Single-stranded DNA-binding protein. 4 111 29.599 T 09-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 L21SP3_RS02085 102c843c7454713fd0ecdb17adfc139b 164 PIRSF PIRSF002070 1 153 2.0E-32 T 09-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 L21SP3_RS02085 102c843c7454713fd0ecdb17adfc139b 164 Pfam PF00436 Single-strand binding protein family 4 106 4.2E-32 T 09-03-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 L21SP3_RS02085 102c843c7454713fd0ecdb17adfc139b 164 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 164 5.4E-44 T 09-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 L21SP3_RS01030 78eae9ef9303bb46065c8ff2ecf56413 398 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 12 393 1.0E-185 T 09-03-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 L21SP3_RS01030 78eae9ef9303bb46065c8ff2ecf56413 398 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 7 396 51.48 T 09-03-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 L21SP3_RS01030 78eae9ef9303bb46065c8ff2ecf56413 398 Gene3D G3DSA:3.40.50.1100 183 397 1.2E-91 T 09-03-2017 L21SP3_RS01030 78eae9ef9303bb46065c8ff2ecf56413 398 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 86 100 - T 09-03-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 L21SP3_RS01030 78eae9ef9303bb46065c8ff2ecf56413 398 Gene3D G3DSA:3.40.50.1100 105 182 1.9E-20 T 09-03-2017 L21SP3_RS01030 78eae9ef9303bb46065c8ff2ecf56413 398 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 383 1.6E-43 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP3_RS01030 78eae9ef9303bb46065c8ff2ecf56413 398 PIRSF PIRSF001413 1 398 1.4E-161 T 09-03-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 L21SP3_RS01030 78eae9ef9303bb46065c8ff2ecf56413 398 SUPERFAMILY SSF53686 8 393 2.49E-142 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP3_RS02755 02bc43f9692a3cc09205a8b04f0e8818 135 SUPERFAMILY SSF54637 1 130 3.34E-35 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS02755 02bc43f9692a3cc09205a8b04f0e8818 135 Pfam PF13279 Thioesterase-like superfamily 9 125 1.3E-11 T 09-03-2017 L21SP3_RS02755 02bc43f9692a3cc09205a8b04f0e8818 135 Gene3D G3DSA:3.10.129.10 1 130 3.6E-36 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS03020 7f65e5cdbb408b188fa71909e5e89a38 152 SUPERFAMILY SSF109635 6 99 1.83E-12 T 09-03-2017 L21SP3_RS03020 7f65e5cdbb408b188fa71909e5e89a38 152 SUPERFAMILY SSF57716 100 133 9.41E-7 T 09-03-2017 L21SP3_RS03020 7f65e5cdbb408b188fa71909e5e89a38 152 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 98 126 2.3E-9 T 09-03-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 L21SP3_RS03020 7f65e5cdbb408b188fa71909e5e89a38 152 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 103 127 - T 09-03-2017 IPR020458 Zinc finger, DksA/TraR C4-type conserved site L21SP3_RS06695 e3469cacd34a7e3a2c4959f04c0f34d4 353 Gene3D G3DSA:3.40.50.410 93 308 7.0E-23 T 09-03-2017 IPR002035 von Willebrand factor, type A L21SP3_RS06695 e3469cacd34a7e3a2c4959f04c0f34d4 353 Pfam PF00092 von Willebrand factor type A domain 93 305 4.6E-20 T 09-03-2017 IPR002035 von Willebrand factor, type A L21SP3_RS06695 e3469cacd34a7e3a2c4959f04c0f34d4 353 SMART SM00327 88 311 3.5E-13 T 09-03-2017 IPR002035 von Willebrand factor, type A L21SP3_RS06695 e3469cacd34a7e3a2c4959f04c0f34d4 353 Pfam PF07584 Aerotolerance regulator N-terminal 1 75 2.5E-8 T 09-03-2017 IPR024163 Aerotolerance regulator, N-terminal L21SP3_RS06695 e3469cacd34a7e3a2c4959f04c0f34d4 353 SUPERFAMILY SSF53300 88 308 1.75E-28 T 09-03-2017 IPR002035 von Willebrand factor, type A L21SP3_RS01025 5d9f90c36aed2d4328b127e0aea52ce2 270 SUPERFAMILY SSF51366 1 256 3.69E-78 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP3_RS01025 5d9f90c36aed2d4328b127e0aea52ce2 270 Gene3D G3DSA:3.20.20.70 1 267 3.9E-86 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS01025 5d9f90c36aed2d4328b127e0aea52ce2 270 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 266 4.8E-73 T 09-03-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 L21SP3_RS01025 5d9f90c36aed2d4328b127e0aea52ce2 270 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 268 32.829 T 09-03-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 L21SP3_RS01025 5d9f90c36aed2d4328b127e0aea52ce2 270 Pfam PF00290 Tryptophan synthase alpha chain 8 267 3.0E-76 T 09-03-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 L21SP3_RS10600 20b0c36d12cd0502d65ad306783eca25 958 SUPERFAMILY SSF51445 72 234 8.66E-17 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS10600 20b0c36d12cd0502d65ad306783eca25 958 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 801 951 3.4E-18 T 09-03-2017 L21SP3_RS10600 20b0c36d12cd0502d65ad306783eca25 958 SUPERFAMILY SSF49899 792 956 1.4E-27 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10600 20b0c36d12cd0502d65ad306783eca25 958 Gene3D G3DSA:2.60.120.200 758 954 1.5E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10600 20b0c36d12cd0502d65ad306783eca25 958 Pfam PF11790 Glycosyl hydrolase catalytic core 35 259 1.1E-37 T 09-03-2017 IPR024655 Uncharacterised protein family, glycosyl hydrolase catalytic domain L21SP3_RS10600 20b0c36d12cd0502d65ad306783eca25 958 Gene3D G3DSA:3.20.20.80 95 234 7.2E-12 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS02015 2f686857def326286c6fe621dcd5df79 442 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 6 438 1.4E-108 T 09-03-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 L21SP3_RS02015 2f686857def326286c6fe621dcd5df79 442 SMART SM00729 150 367 1.2E-42 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP3_RS02015 2f686857def326286c6fe621dcd5df79 442 Pfam PF04055 Radical SAM superfamily 156 325 1.3E-23 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS02015 2f686857def326286c6fe621dcd5df79 442 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 5 441 53.794 T 09-03-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 L21SP3_RS02015 2f686857def326286c6fe621dcd5df79 442 Gene3D G3DSA:3.80.30.20 151 380 9.5E-67 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe L21SP3_RS02015 2f686857def326286c6fe621dcd5df79 442 Gene3D G3DSA:2.40.50.140 382 442 3.4E-12 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS02015 2f686857def326286c6fe621dcd5df79 442 SUPERFAMILY SSF102114 146 374 3.01E-48 T 09-03-2017 L21SP3_RS02015 2f686857def326286c6fe621dcd5df79 442 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 154 174 - T 09-03-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 L21SP3_RS02015 2f686857def326286c6fe621dcd5df79 442 Pfam PF00919 Uncharacterized protein family UPF0004 7 104 7.5E-23 T 09-03-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 L21SP3_RS02015 2f686857def326286c6fe621dcd5df79 442 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 7 438 1.5E-123 T 09-03-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 L21SP3_RS01795 d67327ee35a9a4bff2a7d786ab3c0710 240 SUPERFAMILY SSF75217 1 234 1.18E-97 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases L21SP3_RS01795 d67327ee35a9a4bff2a7d786ab3c0710 240 Gene3D G3DSA:3.40.1280.10 1 160 2.3E-64 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal L21SP3_RS01795 d67327ee35a9a4bff2a7d786ab3c0710 240 Gene3D G3DSA:1.10.1270.20 161 232 2.3E-33 T 09-03-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 L21SP3_RS01795 d67327ee35a9a4bff2a7d786ab3c0710 240 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 233 9.8E-97 T 09-03-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 L21SP3_RS01795 d67327ee35a9a4bff2a7d786ab3c0710 240 PIRSF PIRSF000386 1 240 5.4E-99 T 09-03-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 L21SP3_RS01795 d67327ee35a9a4bff2a7d786ab3c0710 240 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 24 221 8.2E-64 T 09-03-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 L21SP3_RS01795 d67327ee35a9a4bff2a7d786ab3c0710 240 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 240 105.175 T 09-03-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 L21SP3_RS03915 e08b590af02bc83dd3c811760e672799 640 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 48 454 2.7E-96 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS03915 e08b590af02bc83dd3c811760e672799 640 Pfam PF00474 Sodium:solute symporter family 48 454 5.2E-77 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS08320 577dc3626bc6ef0b477a7c37fd998c25 68 Pfam PF03781 Sulfatase-modifying factor enzyme 1 10 52 3.9E-5 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS08320 577dc3626bc6ef0b477a7c37fd998c25 68 SUPERFAMILY SSF56436 11 55 5.18E-9 T 09-03-2017 IPR016187 C-type lectin fold L21SP3_RS08320 577dc3626bc6ef0b477a7c37fd998c25 68 Gene3D G3DSA:3.90.1580.10 10 54 9.0E-11 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS10930 45ac6d8ae2afc2b823a3b319dd888f20 362 SUPERFAMILY SSF51726 84 361 1.74E-32 T 09-03-2017 L21SP3_RS10930 45ac6d8ae2afc2b823a3b319dd888f20 362 Gene3D G3DSA:3.20.20.210 109 361 3.0E-38 T 09-03-2017 L21SP3_RS10930 45ac6d8ae2afc2b823a3b319dd888f20 362 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 118 361 5.2E-26 T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 L21SP3_RS05805 a76fd065ec240c885df2d99215992a83 308 Gene3D G3DSA:3.40.30.10 198 297 5.9E-7 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS05805 a76fd065ec240c885df2d99215992a83 308 SUPERFAMILY SSF52833 200 302 1.74E-7 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS02510 b086fb711a5f4202ee198c1f42c36689 243 SUPERFAMILY SSF56281 6 242 4.85E-57 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS02510 b086fb711a5f4202ee198c1f42c36689 243 Pfam PF00753 Metallo-beta-lactamase superfamily 89 158 4.4E-7 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS02510 b086fb711a5f4202ee198c1f42c36689 243 Pfam PF00753 Metallo-beta-lactamase superfamily 13 70 4.0E-11 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS02510 b086fb711a5f4202ee198c1f42c36689 243 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 1 242 31.442 T 09-03-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 L21SP3_RS02510 b086fb711a5f4202ee198c1f42c36689 243 Gene3D G3DSA:3.60.15.10 4 242 1.0E-70 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS02510 b086fb711a5f4202ee198c1f42c36689 243 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 160 242 1.4E-21 T 09-03-2017 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 L21SP3_RS02510 b086fb711a5f4202ee198c1f42c36689 243 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 10 242 1.7E-65 T 09-03-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 L21SP3_RS02510 b086fb711a5f4202ee198c1f42c36689 243 SMART SM00849 11 158 2.0E-26 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS06875 a00829a420fb81b2bd914bdeacdad6d3 586 Pfam PF07698 7TM receptor with intracellular HD hydrolase 132 320 2.6E-22 T 09-03-2017 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain L21SP3_RS06875 a00829a420fb81b2bd914bdeacdad6d3 586 SUPERFAMILY SSF109604 332 484 5.02E-13 T 09-03-2017 L21SP3_RS06875 a00829a420fb81b2bd914bdeacdad6d3 586 Pfam PF01966 HD domain 345 486 3.8E-16 T 09-03-2017 IPR006674 HD domain L21SP3_RS06875 a00829a420fb81b2bd914bdeacdad6d3 586 SMART SM00471 341 498 1.3E-6 T 09-03-2017 IPR003607 HD/PDEase domain L21SP3_RS06875 a00829a420fb81b2bd914bdeacdad6d3 586 Gene3D G3DSA:1.10.3210.10 341 537 3.0E-21 T 09-03-2017 IPR006674 HD domain L21SP3_RS06875 a00829a420fb81b2bd914bdeacdad6d3 586 TIGRFAM TIGR00277 HDIG: HDIG domain 342 440 2.2E-23 T 09-03-2017 IPR006675 HDIG domain L21SP3_RS06170 6cf5ce7e08cf1c139d2cd52024dd9c96 65 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 59 2.1E-15 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06170 6cf5ce7e08cf1c139d2cd52024dd9c96 65 Pfam PF00831 Ribosomal L29 protein 4 59 5.2E-17 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06170 6cf5ce7e08cf1c139d2cd52024dd9c96 65 SUPERFAMILY SSF46561 1 63 1.31E-17 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06170 6cf5ce7e08cf1c139d2cd52024dd9c96 65 Gene3D G3DSA:1.10.287.310 1 63 4.3E-20 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS06170 6cf5ce7e08cf1c139d2cd52024dd9c96 65 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 13.524 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 PRINTS PR00738 Glycosyl hydrolase family 20 signature 488 504 2.9E-44 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 PRINTS PR00738 Glycosyl hydrolase family 20 signature 172 189 2.9E-44 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 PRINTS PR00738 Glycosyl hydrolase family 20 signature 319 337 2.9E-44 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 PRINTS PR00738 Glycosyl hydrolase family 20 signature 271 288 2.9E-44 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 PRINTS PR00738 Glycosyl hydrolase family 20 signature 201 222 2.9E-44 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 PRINTS PR00738 Glycosyl hydrolase family 20 signature 135 155 2.9E-44 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 PRINTS PR00738 Glycosyl hydrolase family 20 signature 341 354 2.9E-44 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 PRINTS PR00738 Glycosyl hydrolase family 20 signature 506 523 2.9E-44 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 SUPERFAMILY SSF55545 49 177 8.37E-22 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 Gene3D G3DSA:3.20.20.80 176 557 6.3E-143 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 50 175 1.6E-18 T 09-03-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 SUPERFAMILY SSF51445 178 537 9.69E-130 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 PIRSF PIRSF001093 31 564 2.9E-77 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 Gene3D G3DSA:3.30.379.10 31 175 1.1E-24 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 L21SP3_RS07820 b10f11922557b40b18e680c5654d26f6 565 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 178 524 1.6E-124 T 09-03-2017 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 L21SP3_RS08545 a79c44ff632cacc744b7a6ec1f2a9fd7 184 PIRSF PIRSF015617 1 184 3.8E-59 T 09-03-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 L21SP3_RS08545 a79c44ff632cacc744b7a6ec1f2a9fd7 184 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 14 183 5.4E-61 T 09-03-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 L21SP3_RS08545 a79c44ff632cacc744b7a6ec1f2a9fd7 184 Gene3D G3DSA:3.40.50.300 5 183 1.2E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08545 a79c44ff632cacc744b7a6ec1f2a9fd7 184 SUPERFAMILY SSF52540 12 183 3.38E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07195 6d77025674956de5ab65cbcfc8b8f9ca 388 Gene3D G3DSA:3.90.350.10 255 310 2.4E-6 T 09-03-2017 IPR014736 Transposase, Tn5-like, core L21SP3_RS07195 6d77025674956de5ab65cbcfc8b8f9ca 388 Pfam PF14294 Domain of unknown function (DUF4372) 6 76 2.6E-24 T 09-03-2017 IPR025399 Domain of unknown function DUF4372 L21SP3_RS07195 6d77025674956de5ab65cbcfc8b8f9ca 388 Pfam PF01609 Transposase DDE domain 121 332 5.2E-28 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS07195 6d77025674956de5ab65cbcfc8b8f9ca 388 SUPERFAMILY SSF53098 120 354 5.46E-27 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS10005 8d648dc70e4a8e9a1e521a556293d9ae 960 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 25 187 7.8E-13 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS10005 8d648dc70e4a8e9a1e521a556293d9ae 960 SUPERFAMILY SSF51445 537 654 5.63E-48 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS10005 8d648dc70e4a8e9a1e521a556293d9ae 960 SUPERFAMILY SSF51445 328 504 5.63E-48 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS10005 8d648dc70e4a8e9a1e521a556293d9ae 960 SUPERFAMILY SSF49785 14 69 2.98E-32 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10005 8d648dc70e4a8e9a1e521a556293d9ae 960 SUPERFAMILY SSF49785 114 221 2.98E-32 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10005 8d648dc70e4a8e9a1e521a556293d9ae 960 Gene3D G3DSA:3.20.20.80 334 666 4.0E-34 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS10005 8d648dc70e4a8e9a1e521a556293d9ae 960 Pfam PF00703 Glycosyl hydrolases family 2 224 331 6.5E-9 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS10005 8d648dc70e4a8e9a1e521a556293d9ae 960 Gene3D G3DSA:2.60.40.320 214 332 1.2E-7 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS10005 8d648dc70e4a8e9a1e521a556293d9ae 960 Gene3D G3DSA:2.60.120.260 20 213 6.5E-34 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS03365 992959f738faeaafc4c84b40e912ecc5 243 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 25 1.2E-4 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS03365 992959f738faeaafc4c84b40e912ecc5 243 SUPERFAMILY SSF54523 9 76 1.8E-11 T 09-03-2017 L21SP3_RS03365 992959f738faeaafc4c84b40e912ecc5 243 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 28 1.2E-5 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS03365 992959f738faeaafc4c84b40e912ecc5 243 Gene3D G3DSA:3.30.700.10 9 65 2.3E-5 T 09-03-2017 L21SP3_RS03365 992959f738faeaafc4c84b40e912ecc5 243 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 7 27 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS07415 ff327931e314c118af50031f2e71310d 401 SUPERFAMILY SSF161098 191 381 6.93E-25 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS07415 ff327931e314c118af50031f2e71310d 401 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 214 399 1.0E-28 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS07415 ff327931e314c118af50031f2e71310d 401 Gene3D G3DSA:1.10.3720.10 189 395 1.4E-23 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 L21SP3_RS07415 ff327931e314c118af50031f2e71310d 401 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 15 55 3.3E-11 T 09-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain L21SP3_RS08850 1fd5142e1a9ccae5206c5398fabb5be5 539 SMART SM00710 113 146 1500.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08850 1fd5142e1a9ccae5206c5398fabb5be5 539 SMART SM00710 285 311 2500.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08850 1fd5142e1a9ccae5206c5398fabb5be5 539 SMART SM00710 229 251 3000.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08850 1fd5142e1a9ccae5206c5398fabb5be5 539 SMART SM00710 313 350 8300.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08850 1fd5142e1a9ccae5206c5398fabb5be5 539 SMART SM00710 198 220 170.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08850 1fd5142e1a9ccae5206c5398fabb5be5 539 SMART SM00710 252 284 1900.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08850 1fd5142e1a9ccae5206c5398fabb5be5 539 SMART SM00710 382 406 4600.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS08850 1fd5142e1a9ccae5206c5398fabb5be5 539 SUPERFAMILY SSF51126 11 267 3.62E-24 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS08850 1fd5142e1a9ccae5206c5398fabb5be5 539 Gene3D G3DSA:2.160.20.10 181 211 5.3E-39 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS08850 1fd5142e1a9ccae5206c5398fabb5be5 539 Gene3D G3DSA:2.160.20.10 243 538 5.3E-39 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS08850 1fd5142e1a9ccae5206c5398fabb5be5 539 Gene3D G3DSA:2.160.20.10 11 125 5.3E-39 T 09-03-2017 IPR012334 Pectin lyase fold L21SP3_RS08850 1fd5142e1a9ccae5206c5398fabb5be5 539 SUPERFAMILY SSF51126 275 538 9.43E-14 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS08850 1fd5142e1a9ccae5206c5398fabb5be5 539 Pfam PF13229 Right handed beta helix region 185 349 3.9E-9 T 09-03-2017 L21SP3_RS04815 4c38d146951070230d05659fc8941075 319 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 4 317 48.106 T 09-03-2017 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 L21SP3_RS04815 4c38d146951070230d05659fc8941075 319 Gene3D G3DSA:3.90.25.10 262 308 8.9E-39 T 09-03-2017 L21SP3_RS04815 4c38d146951070230d05659fc8941075 319 Gene3D G3DSA:3.90.25.10 170 210 8.9E-39 T 09-03-2017 L21SP3_RS04815 4c38d146951070230d05659fc8941075 319 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 230 2.5E-68 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 L21SP3_RS04815 4c38d146951070230d05659fc8941075 319 SUPERFAMILY SSF51735 3 315 1.82E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04815 4c38d146951070230d05659fc8941075 319 Gene3D G3DSA:3.40.50.720 3 169 4.7E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04815 4c38d146951070230d05659fc8941075 319 Gene3D G3DSA:3.40.50.720 211 261 4.7E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS06240 5f0cd3217d280a5cb5f8c42408497b55 266 PIRSF PIRSF019254 1 266 1.6E-91 T 09-03-2017 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 L21SP3_RS06240 5f0cd3217d280a5cb5f8c42408497b55 266 Pfam PF04454 Encapsulating protein for peroxidase 3 253 9.6E-84 T 09-03-2017 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 L21SP3_RS07915 6d933d2f0e965d3805883005e1db7299 113 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 09-03-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 L21SP3_RS07915 6d933d2f0e965d3805883005e1db7299 113 Gene3D G3DSA:3.30.70.120 1 112 3.8E-40 T 09-03-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal L21SP3_RS07915 6d933d2f0e965d3805883005e1db7299 113 PRINTS PR00340 P-II protein signature 52 75 2.6E-25 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP3_RS07915 6d933d2f0e965d3805883005e1db7299 113 PRINTS PR00340 P-II protein signature 23 41 2.6E-25 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP3_RS07915 6d933d2f0e965d3805883005e1db7299 113 PRINTS PR00340 P-II protein signature 83 103 2.6E-25 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP3_RS07915 6d933d2f0e965d3805883005e1db7299 113 PRINTS PR00340 P-II protein signature 2 17 2.6E-25 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP3_RS07915 6d933d2f0e965d3805883005e1db7299 113 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.9E-34 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP3_RS07915 6d933d2f0e965d3805883005e1db7299 113 SMART SM00938 4 105 3.2E-48 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 L21SP3_RS07915 6d933d2f0e965d3805883005e1db7299 113 SUPERFAMILY SSF54913 1 112 6.99E-37 T 09-03-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta L21SP3_RS10490 0461766bc0dec692e02e3cb034ec958a 294 Pfam PF13633 Prokaryotic N-terminal methylation site 4 29 5.0E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS10490 0461766bc0dec692e02e3cb034ec958a 294 Gene3D G3DSA:3.30.700.10 6 29 8.1E-5 T 09-03-2017 L21SP3_RS10490 0461766bc0dec692e02e3cb034ec958a 294 SUPERFAMILY SSF54523 6 96 2.83E-14 T 09-03-2017 L21SP3_RS10490 0461766bc0dec692e02e3cb034ec958a 294 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 25 7.3E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS10490 0461766bc0dec692e02e3cb034ec958a 294 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 245 257 4.9E-4 T 09-03-2017 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP3_RS10490 0461766bc0dec692e02e3cb034ec958a 294 Pfam PF07596 Protein of unknown function (DUF1559) 31 65 3.0E-4 T 09-03-2017 IPR011453 Protein of unknown function DUF1559 L21SP3_RS10530 af726789af4cb2b912cdcea1f060dedd 875 Pfam PF05089 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain 124 459 3.7E-122 T 09-03-2017 IPR024733 Alpha-N-acetylglucosaminidase, tim-barrel domain KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096|Reactome: R-HSA-2206282 L21SP3_RS10530 af726789af4cb2b912cdcea1f060dedd 875 Gene3D G3DSA:2.60.120.260 737 869 5.0E-19 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10530 af726789af4cb2b912cdcea1f060dedd 875 Pfam PF12971 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain 29 109 1.1E-22 T 09-03-2017 IPR024240 Alpha-N-acetylglucosaminidase, N-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096|Reactome: R-HSA-2206282 L21SP3_RS10530 af726789af4cb2b912cdcea1f060dedd 875 SUPERFAMILY SSF49785 736 870 6.17E-19 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10530 af726789af4cb2b912cdcea1f060dedd 875 Pfam PF12972 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain 467 716 6.5E-59 T 09-03-2017 IPR024732 Alpha-N-acetylglucosaminidase, C-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096|Reactome: R-HSA-2206282 L21SP3_RS10530 af726789af4cb2b912cdcea1f060dedd 875 Pfam PF00754 F5/8 type C domain 747 865 4.7E-13 T 09-03-2017 IPR000421 Coagulation factor 5/8 C-terminal domain L21SP3_RS03735 c737b2dc82b9aba6cb6f44259eb5891b 372 Gene3D G3DSA:3.40.50.2000 157 346 1.2E-20 T 09-03-2017 L21SP3_RS03735 c737b2dc82b9aba6cb6f44259eb5891b 372 SUPERFAMILY SSF53756 2 368 6.28E-74 T 09-03-2017 L21SP3_RS03735 c737b2dc82b9aba6cb6f44259eb5891b 372 Pfam PF13439 Glycosyltransferase Family 4 16 175 1.3E-16 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 L21SP3_RS03735 c737b2dc82b9aba6cb6f44259eb5891b 372 Pfam PF00534 Glycosyl transferases group 1 189 347 1.9E-33 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS06185 859b32351281babb4ae6e08e2ddd73b2 139 Gene3D G3DSA:3.90.470.10 29 135 6.6E-32 T 09-03-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06185 859b32351281babb4ae6e08e2ddd73b2 139 Pfam PF00237 Ribosomal protein L22p/L17e 32 133 9.0E-27 T 09-03-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06185 859b32351281babb4ae6e08e2ddd73b2 139 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 25 136 22.285 T 09-03-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06185 859b32351281babb4ae6e08e2ddd73b2 139 SUPERFAMILY SSF54843 26 135 5.62E-31 T 09-03-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06185 859b32351281babb4ae6e08e2ddd73b2 139 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 30 133 6.9E-28 T 09-03-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS00220 efc3c6d5142fa13020b90a0dd9b508a5 641 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 518 590 7.7E-10 T 09-03-2017 L21SP3_RS00220 efc3c6d5142fa13020b90a0dd9b508a5 641 SUPERFAMILY SSF48726 327 414 5.84E-7 T 09-03-2017 IPR007110 Immunoglobulin-like domain GO:0005515 L21SP3_RS00220 efc3c6d5142fa13020b90a0dd9b508a5 641 Gene3D G3DSA:2.60.40.10 226 311 9.2E-4 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS00220 efc3c6d5142fa13020b90a0dd9b508a5 641 Gene3D G3DSA:2.60.40.10 325 410 2.3E-5 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS00220 efc3c6d5142fa13020b90a0dd9b508a5 641 Gene3D G3DSA:2.60.120.200 412 593 2.7E-15 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00220 efc3c6d5142fa13020b90a0dd9b508a5 641 SUPERFAMILY SSF49899 418 593 3.8E-18 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS06355 d3dd54fefd3142c592132b9826e10d15 127 Gene3D G3DSA:1.10.287.920 52 100 0.001 T 09-03-2017 IPR027458 Pheromone alpha factor receptor, double transmembrane domain L21SP3_RS08450 782d264776758ac2b51de7a706735937 204 Gene3D G3DSA:3.30.420.10 30 202 1.9E-48 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS08450 782d264776758ac2b51de7a706735937 204 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 32 200 1.0E-27 T 09-03-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS08450 782d264776758ac2b51de7a706735937 204 SUPERFAMILY SSF53098 28 199 5.94E-47 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS08450 782d264776758ac2b51de7a706735937 204 SMART SM00479 33 202 8.5E-43 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III L21SP3_RS08450 782d264776758ac2b51de7a706735937 204 Pfam PF00929 Exonuclease 35 192 6.8E-31 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III L21SP3_RS04340 27e3b4e9051c2cb66d9c05f610afeb87 422 Pfam PF02687 FtsX-like permease family 303 415 4.7E-22 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 L21SP3_RS04340 27e3b4e9051c2cb66d9c05f610afeb87 422 Pfam PF12704 MacB-like periplasmic core domain 21 251 9.9E-22 T 09-03-2017 IPR025857 MacB-like periplasmic core domain L21SP3_RS10435 7f4bfa380c42ec3c2fcf8d4aadc2b05f 427 SUPERFAMILY SSF75005 25 317 6.14E-71 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS10435 7f4bfa380c42ec3c2fcf8d4aadc2b05f 427 Pfam PF04616 Glycosyl hydrolases family 43 26 316 6.2E-48 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS10435 7f4bfa380c42ec3c2fcf8d4aadc2b05f 427 Gene3D G3DSA:2.115.10.20 20 318 4.2E-83 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS04735 36b78e48777a1aa454dfb22914aca955 308 Gene3D G3DSA:3.90.25.10 171 290 7.7E-38 T 09-03-2017 L21SP3_RS04735 36b78e48777a1aa454dfb22914aca955 308 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 235 5.3E-59 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 L21SP3_RS04735 36b78e48777a1aa454dfb22914aca955 308 SUPERFAMILY SSF51735 1 304 1.26E-92 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04735 36b78e48777a1aa454dfb22914aca955 308 Gene3D G3DSA:3.40.50.720 1 170 1.1E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS05480 cde82fba06cb8cedf31e4c2a2906c3e2 321 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 9 305 8.1E-40 T 09-03-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 L21SP3_RS05480 cde82fba06cb8cedf31e4c2a2906c3e2 321 PIRSF PIRSF026649 8 313 6.0E-60 T 09-03-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 L21SP3_RS08375 b522cc7f3eac663b681de3d4ea20bd3b 139 Gene3D G3DSA:3.30.2190.10 1 104 3.4E-42 T 09-03-2017 IPR018594 Domain of unknown function DUF2023 L21SP3_RS08375 b522cc7f3eac663b681de3d4ea20bd3b 139 SUPERFAMILY SSF160448 1 102 4.58E-39 T 09-03-2017 IPR018594 Domain of unknown function DUF2023 L21SP3_RS08375 b522cc7f3eac663b681de3d4ea20bd3b 139 Pfam PF09633 Protein of unknown function (DUF2023) 3 101 4.2E-39 T 09-03-2017 IPR018594 Domain of unknown function DUF2023 L21SP3_RS00560 abc1057714f82c94f5104b18f7632536 306 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 5 301 8.3E-73 T 09-03-2017 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 L21SP3_RS00560 abc1057714f82c94f5104b18f7632536 306 Pfam PF13484 4Fe-4S double cluster binding domain 184 248 4.1E-15 T 09-03-2017 L21SP3_RS00560 abc1057714f82c94f5104b18f7632536 306 Gene3D G3DSA:3.30.70.20 180 248 1.0E-8 T 09-03-2017 L21SP3_RS00560 abc1057714f82c94f5104b18f7632536 306 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 185 196 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS00560 abc1057714f82c94f5104b18f7632536 306 Pfam PF08331 Domain of unknown function (DUF1730) 55 131 6.5E-15 T 09-03-2017 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 L21SP3_RS00560 abc1057714f82c94f5104b18f7632536 306 SUPERFAMILY SSF54862 180 248 2.85E-11 T 09-03-2017 L21SP3_RS05600 b99cee1b7472b07ac95a5ab4d426725c 350 SMART SM01133 69 326 9.0E-37 T 09-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 L21SP3_RS05600 b99cee1b7472b07ac95a5ab4d426725c 350 Gene3D G3DSA:3.20.20.70 53 345 7.5E-95 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS05600 b99cee1b7472b07ac95a5ab4d426725c 350 SUPERFAMILY SSF51569 63 243 3.66E-62 T 09-03-2017 L21SP3_RS05600 b99cee1b7472b07ac95a5ab4d426725c 350 SUPERFAMILY SSF51569 271 344 3.66E-62 T 09-03-2017 L21SP3_RS05600 b99cee1b7472b07ac95a5ab4d426725c 350 Pfam PF01791 DeoC/LacD family aldolase 70 326 5.8E-63 T 09-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 L21SP3_RS11130 5c60f47d7b0114523c79c8f72bfda33b 227 SUPERFAMILY SSF52833 96 225 1.13E-31 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS11130 5c60f47d7b0114523c79c8f72bfda33b 227 Pfam PF00578 AhpC/TSA family 95 209 7.3E-24 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 L21SP3_RS11130 5c60f47d7b0114523c79c8f72bfda33b 227 ProSitePatterns PS00194 Thioredoxin family active site. 122 140 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 L21SP3_RS11130 5c60f47d7b0114523c79c8f72bfda33b 227 Gene3D G3DSA:3.40.30.10 95 225 4.0E-38 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS09470 6eef554a6b0b9bcecfb8d95cbcfcffcc 249 SUPERFAMILY SSF53271 71 242 2.88E-24 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like L21SP3_RS09470 6eef554a6b0b9bcecfb8d95cbcfcffcc 249 Pfam PF00156 Phosphoribosyl transferase domain 151 242 3.9E-7 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 L21SP3_RS09470 6eef554a6b0b9bcecfb8d95cbcfcffcc 249 Gene3D G3DSA:3.40.50.2020 90 243 1.5E-27 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like L21SP3_RS09150 fd09f3fbcc67ec13fffcab5200af7a4b 233 SUPERFAMILY SSF52540 10 149 5.33E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09150 fd09f3fbcc67ec13fffcab5200af7a4b 233 Gene3D G3DSA:3.40.50.300 10 169 3.6E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09150 fd09f3fbcc67ec13fffcab5200af7a4b 233 Pfam PF13175 AAA ATPase domain 10 203 4.4E-11 T 09-03-2017 L21SP3_RS08760 7fed2818642c107bfe3958fc43fbe48e 226 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 16 209 4.1E-15 T 09-03-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 L21SP3_RS08760 7fed2818642c107bfe3958fc43fbe48e 226 SUPERFAMILY SSF56300 16 216 3.38E-40 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS08760 7fed2818642c107bfe3958fc43fbe48e 226 Gene3D G3DSA:3.60.21.10 14 215 2.1E-29 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS04325 7a5f8c4a6bf9a51718e3b39691548bcc 293 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 65 85 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS04325 7a5f8c4a6bf9a51718e3b39691548bcc 293 SUPERFAMILY SSF54523 67 152 1.65E-15 T 09-03-2017 L21SP3_RS04325 7a5f8c4a6bf9a51718e3b39691548bcc 293 PRINTS PR00813 Bacterial general secretion pathway protein G signature 66 91 5.5E-6 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS04325 7a5f8c4a6bf9a51718e3b39691548bcc 293 PRINTS PR00813 Bacterial general secretion pathway protein G signature 102 120 5.5E-6 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS04325 7a5f8c4a6bf9a51718e3b39691548bcc 293 TIGRFAM TIGR04294 pre_pil_HX9DG: prepilin-type processing-associated H-X9-DG domain 250 265 1.5E-5 T 09-03-2017 IPR027558 Prepilin-type processing-associated H-X9-DG domain L21SP3_RS04325 7a5f8c4a6bf9a51718e3b39691548bcc 293 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 65 87 5.0E-6 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS04325 7a5f8c4a6bf9a51718e3b39691548bcc 293 Pfam PF13633 Prokaryotic N-terminal methylation site 65 90 1.0E-6 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS04325 7a5f8c4a6bf9a51718e3b39691548bcc 293 Gene3D G3DSA:3.30.700.10 67 122 4.5E-6 T 09-03-2017 L21SP3_RS03200 5390dd7354c3317ce61814e5c3476407 384 SUPERFAMILY SSF75005 37 156 7.57E-57 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS03200 5390dd7354c3317ce61814e5c3476407 384 SUPERFAMILY SSF75005 209 381 7.57E-57 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS03200 5390dd7354c3317ce61814e5c3476407 384 Pfam PF04616 Glycosyl hydrolases family 43 209 303 2.3E-8 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS03200 5390dd7354c3317ce61814e5c3476407 384 Gene3D G3DSA:2.115.10.20 45 159 7.0E-34 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS03200 5390dd7354c3317ce61814e5c3476407 384 Gene3D G3DSA:2.115.10.20 205 317 7.0E-34 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS01640 7f56b8b006cb8b7953ce57ba9a240a4b 379 SUPERFAMILY SSF46689 272 320 4.37E-7 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS01640 7f56b8b006cb8b7953ce57ba9a240a4b 379 Gene3D G3DSA:1.10.10.60 326 375 2.3E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS01640 7f56b8b006cb8b7953ce57ba9a240a4b 379 SUPERFAMILY SSF53822 17 286 1.18E-27 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS01640 7f56b8b006cb8b7953ce57ba9a240a4b 379 Gene3D G3DSA:3.40.50.2300 110 242 5.9E-22 T 09-03-2017 L21SP3_RS01640 7f56b8b006cb8b7953ce57ba9a240a4b 379 Pfam PF13377 Periplasmic binding protein-like domain 106 265 3.3E-26 T 09-03-2017 L21SP3_RS01640 7f56b8b006cb8b7953ce57ba9a240a4b 379 Gene3D G3DSA:1.10.10.60 271 325 2.2E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS01640 7f56b8b006cb8b7953ce57ba9a240a4b 379 SUPERFAMILY SSF46689 325 375 1.22E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS01640 7f56b8b006cb8b7953ce57ba9a240a4b 379 SMART SM00342 289 372 2.4E-23 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS01640 7f56b8b006cb8b7953ce57ba9a240a4b 379 Gene3D G3DSA:3.40.50.2300 2 109 6.1E-6 T 09-03-2017 L21SP3_RS01640 7f56b8b006cb8b7953ce57ba9a240a4b 379 Pfam PF12833 Helix-turn-helix domain 296 374 1.7E-20 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 L21SP3_RS07670 ff800c85b019df57acec3d2cf6f476fa 153 SUPERFAMILY SSF47240 1 152 7.78E-22 T 09-03-2017 IPR009078 Ferritin-like superfamily L21SP3_RS07670 ff800c85b019df57acec3d2cf6f476fa 153 Pfam PF13668 Ferritin-like domain 4 148 6.5E-8 T 09-03-2017 L21SP3_RS07670 ff800c85b019df57acec3d2cf6f476fa 153 Gene3D G3DSA:1.20.1260.10 2 152 5.7E-29 T 09-03-2017 IPR012347 Ferritin-related L21SP3_RS09205 c500fbd725601e0bb5418f6d64f68efc 120 Gene3D G3DSA:3.30.420.130 1 113 1.1E-34 T 09-03-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP3_RS09205 c500fbd725601e0bb5418f6d64f68efc 120 SUPERFAMILY SSF53146 1 119 1.57E-30 T 09-03-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP3_RS09205 c500fbd725601e0bb5418f6d64f68efc 120 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 103 1.5E-23 T 09-03-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP3_RS09300 cf68114977afdb4f35fd005070ff7321 270 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS09300 cf68114977afdb4f35fd005070ff7321 270 SUPERFAMILY SSF54523 11 116 1.33E-14 T 09-03-2017 L21SP3_RS09300 cf68114977afdb4f35fd005070ff7321 270 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 30 8.3E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS09300 cf68114977afdb4f35fd005070ff7321 270 Gene3D G3DSA:3.30.700.10 11 42 4.2E-5 T 09-03-2017 L21SP3_RS09300 cf68114977afdb4f35fd005070ff7321 270 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 5 30 1.8E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS09300 cf68114977afdb4f35fd005070ff7321 270 Pfam PF07596 Protein of unknown function (DUF1559) 36 179 3.4E-4 T 09-03-2017 IPR011453 Protein of unknown function DUF1559 L21SP3_RS09905 3522118c6e2acf873576715731a7d18d 354 Pfam PF00953 Glycosyl transferase family 4 77 224 7.3E-32 T 09-03-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 L21SP3_RS07955 dc91b2d9162c2164360a1dc3f30784a2 133 Gene3D G3DSA:1.20.120.420 48 117 8.8E-4 T 09-03-2017 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 L21SP3_RS03040 72a86121ba6188c4150e3e109629010a 409 Gene3D G3DSA:3.40.50.300 5 169 2.3E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03040 72a86121ba6188c4150e3e109629010a 409 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 164 3.1E-23 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 L21SP3_RS03040 72a86121ba6188c4150e3e109629010a 409 TIGRFAM TIGR03918 GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF 3 394 2.4E-165 T 09-03-2017 IPR023873 [FeFe]-hydrogenase H-cluster maturation GTPase HydF L21SP3_RS03040 72a86121ba6188c4150e3e109629010a 409 Pfam PF01926 50S ribosome-binding GTPase 12 125 3.4E-18 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 L21SP3_RS03040 72a86121ba6188c4150e3e109629010a 409 SUPERFAMILY SSF52540 10 173 1.22E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05675 45732f506fc833c6b98e04f494af58b0 137 Pfam PF04892 VanZ like family 38 123 3.1E-8 T 09-03-2017 IPR006976 VanZ-like L21SP3_RS02750 414c48eaa6a448b13ed651915279725d 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.6E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS02750 414c48eaa6a448b13ed651915279725d 422 Pfam PF01609 Transposase DDE domain 275 412 3.3E-7 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS05620 3c637ece19828ab9491996f916e017da 434 Pfam PF00501 AMP-binding enzyme 13 285 1.5E-14 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 L21SP3_RS05620 3c637ece19828ab9491996f916e017da 434 Gene3D G3DSA:3.30.300.30 324 431 2.1E-37 T 09-03-2017 L21SP3_RS05620 3c637ece19828ab9491996f916e017da 434 SUPERFAMILY SSF56801 44 397 1.7E-53 T 09-03-2017 L21SP3_RS05620 3c637ece19828ab9491996f916e017da 434 Pfam PF14535 AMP-binding enzyme C-terminal domain 334 431 3.4E-33 T 09-03-2017 IPR028154 AMP-dependent ligase, C-terminal L21SP3_RS05620 3c637ece19828ab9491996f916e017da 434 PIRSF PIRSF006444 1 433 2.8E-195 T 09-03-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 L21SP3_RS05620 3c637ece19828ab9491996f916e017da 434 Gene3D G3DSA:3.40.50.980 88 244 1.9E-12 T 09-03-2017 L21SP3_RS06470 f78fab1c414751ed4cfe76e0e617de0e 221 Gene3D G3DSA:3.40.50.720 77 212 5.0E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS06470 f78fab1c414751ed4cfe76e0e617de0e 221 Gene3D G3DSA:1.10.10.10 5 75 5.7E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS06470 f78fab1c414751ed4cfe76e0e617de0e 221 Pfam PF06971 Putative DNA-binding protein N-terminus 6 53 7.1E-18 T 09-03-2017 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 L21SP3_RS06470 f78fab1c414751ed4cfe76e0e617de0e 221 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 209 30.284 T 09-03-2017 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 L21SP3_RS06470 f78fab1c414751ed4cfe76e0e617de0e 221 Pfam PF02629 CoA binding domain 84 178 1.0E-17 T 09-03-2017 IPR003781 CoA-binding GO:0048037 L21SP3_RS06470 f78fab1c414751ed4cfe76e0e617de0e 221 SUPERFAMILY SSF46785 9 79 2.04E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS06470 f78fab1c414751ed4cfe76e0e617de0e 221 SMART SM00881 79 180 4.2E-9 T 09-03-2017 IPR003781 CoA-binding GO:0048037 L21SP3_RS06470 f78fab1c414751ed4cfe76e0e617de0e 221 SUPERFAMILY SSF51735 84 201 4.65E-20 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS00700 2e7894e562efc7458a22e024677bd7c6 410 Pfam PF01595 Domain of unknown function DUF21 14 192 3.2E-34 T 09-03-2017 IPR002550 Domain of unknown function DUF21 L21SP3_RS00700 2e7894e562efc7458a22e024677bd7c6 410 Pfam PF03471 Transporter associated domain 334 409 1.6E-17 T 09-03-2017 IPR005170 Transporter-associated domain L21SP3_RS00700 2e7894e562efc7458a22e024677bd7c6 410 SUPERFAMILY SSF56176 331 409 2.34E-15 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 L21SP3_RS00700 2e7894e562efc7458a22e024677bd7c6 410 Pfam PF00571 CBS domain 207 262 1.9E-7 T 09-03-2017 IPR000644 CBS domain L21SP3_RS00700 2e7894e562efc7458a22e024677bd7c6 410 Gene3D G3DSA:3.10.580.10 193 314 3.7E-17 T 09-03-2017 L21SP3_RS00700 2e7894e562efc7458a22e024677bd7c6 410 SUPERFAMILY SSF54631 195 321 1.52E-25 T 09-03-2017 L21SP3_RS00700 2e7894e562efc7458a22e024677bd7c6 410 SMART SM01091 333 410 1.2E-15 T 09-03-2017 IPR005170 Transporter-associated domain L21SP3_RS00700 2e7894e562efc7458a22e024677bd7c6 410 Gene3D G3DSA:3.30.465.10 315 408 3.5E-21 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 L21SP3_RS07410 2c33e62f1614261334f8761fd3b5705f 277 Pfam PF01040 UbiA prenyltransferase family 26 245 3.4E-22 T 09-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 L21SP3_RS08035 afddd48dda62e9b7e42522c036e83080 249 Gene3D G3DSA:3.40.50.720 2 230 4.0E-73 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS08035 afddd48dda62e9b7e42522c036e83080 249 SUPERFAMILY SSF51735 4 233 5.22E-71 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS08035 afddd48dda62e9b7e42522c036e83080 249 Pfam PF00106 short chain dehydrogenase 7 195 1.1E-58 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS08035 afddd48dda62e9b7e42522c036e83080 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 3.7E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS08035 afddd48dda62e9b7e42522c036e83080 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.7E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS08035 afddd48dda62e9b7e42522c036e83080 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.7E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS08035 afddd48dda62e9b7e42522c036e83080 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.7E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS08035 afddd48dda62e9b7e42522c036e83080 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.7E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS08035 afddd48dda62e9b7e42522c036e83080 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.7E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS08035 afddd48dda62e9b7e42522c036e83080 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.9E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS08035 afddd48dda62e9b7e42522c036e83080 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 8.9E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS08035 afddd48dda62e9b7e42522c036e83080 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 8.9E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS03090 5a7a0514247e20f7a56f540434d9e38d 368 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 363 2.2E-116 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP3_RS03090 5a7a0514247e20f7a56f540434d9e38d 368 Gene3D G3DSA:3.40.640.10 15 244 2.0E-78 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS03090 5a7a0514247e20f7a56f540434d9e38d 368 Gene3D G3DSA:3.90.1150.10 246 367 5.7E-38 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS03090 5a7a0514247e20f7a56f540434d9e38d 368 SUPERFAMILY SSF53383 15 366 2.1E-108 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS03090 5a7a0514247e20f7a56f540434d9e38d 368 PIRSF PIRSF000390 2 367 3.5E-107 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP3_RS03145 50fecd245b0b73710d59399b72b041d3 329 Gene3D G3DSA:3.30.420.40 151 303 1.0E-44 T 09-03-2017 L21SP3_RS03145 50fecd245b0b73710d59399b72b041d3 329 Gene3D G3DSA:3.30.420.40 9 150 2.8E-43 T 09-03-2017 L21SP3_RS03145 50fecd245b0b73710d59399b72b041d3 329 Pfam PF00480 ROK family 14 324 1.3E-66 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 L21SP3_RS03145 50fecd245b0b73710d59399b72b041d3 329 SUPERFAMILY SSF53067 13 324 1.3E-59 T 09-03-2017 L21SP3_RS01445 9f7679af50bf953379dcc68765182370 191 Pfam PF02361 Cobalt transport protein 38 150 1.2E-13 T 09-03-2017 IPR003339 ABC/ECF transporter, transmembrane component L21SP3_RS04305 4ad77bda38e1479f4b581938d1125e5d 188 Gene3D G3DSA:1.20.1440.20 17 188 4.8E-71 T 09-03-2017 IPR023353 LemA-like domain L21SP3_RS04305 4ad77bda38e1479f4b581938d1125e5d 188 SUPERFAMILY SSF140478 29 176 4.58E-60 T 09-03-2017 IPR023353 LemA-like domain L21SP3_RS04305 4ad77bda38e1479f4b581938d1125e5d 188 Pfam PF04011 LemA family 10 188 6.3E-75 T 09-03-2017 IPR007156 LemA L21SP3_RS08910 9d561cc32dc7aaa3cf4e4b74052a9ba5 361 Gene3D G3DSA:2.115.10.20 222 272 9.8E-5 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS08910 9d561cc32dc7aaa3cf4e4b74052a9ba5 361 Gene3D G3DSA:2.115.10.20 54 139 1.6E-5 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS08910 9d561cc32dc7aaa3cf4e4b74052a9ba5 361 SUPERFAMILY SSF75005 197 332 1.08E-14 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS08910 9d561cc32dc7aaa3cf4e4b74052a9ba5 361 SUPERFAMILY SSF75005 50 139 1.08E-14 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS08910 9d561cc32dc7aaa3cf4e4b74052a9ba5 361 Gene3D G3DSA:2.115.10.20 140 221 1.3E-6 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS04685 5c5d5595d2e7d06895a7633fa368f680 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 364 378 6.8E-20 T 09-03-2017 IPR003004 GspF/PilC family L21SP3_RS04685 5c5d5595d2e7d06895a7633fa368f680 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 61 73 6.8E-20 T 09-03-2017 IPR003004 GspF/PilC family L21SP3_RS04685 5c5d5595d2e7d06895a7633fa368f680 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 160 188 6.8E-20 T 09-03-2017 IPR003004 GspF/PilC family L21SP3_RS04685 5c5d5595d2e7d06895a7633fa368f680 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 380 399 6.8E-20 T 09-03-2017 IPR003004 GspF/PilC family L21SP3_RS04685 5c5d5595d2e7d06895a7633fa368f680 400 Pfam PF00482 Type II secretion system (T2SS), protein F 268 391 2.1E-25 T 09-03-2017 IPR018076 Type II secretion system F domain L21SP3_RS04685 5c5d5595d2e7d06895a7633fa368f680 400 Pfam PF00482 Type II secretion system (T2SS), protein F 66 188 8.0E-30 T 09-03-2017 IPR018076 Type II secretion system F domain L21SP3_RS05345 3f4f4bc1610a6bf7580e94cb30362e40 564 PRINTS PR00811 Bacterial general secretion pathway protein D signature 134 144 7.3E-5 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS05345 3f4f4bc1610a6bf7580e94cb30362e40 564 PRINTS PR00811 Bacterial general secretion pathway protein D signature 337 355 7.3E-5 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS05345 3f4f4bc1610a6bf7580e94cb30362e40 564 PRINTS PR00811 Bacterial general secretion pathway protein D signature 207 231 7.3E-5 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS05345 3f4f4bc1610a6bf7580e94cb30362e40 564 Pfam PF00263 Bacterial type II and III secretion system protein 212 371 2.0E-25 T 09-03-2017 IPR004846 Type II/III secretion system GO:0009306 L21SP3_RS10905 f42ad2071cc24946706cd060b48dcd5e 557 Pfam PF08305 NPCBM/NEW2 domain 447 554 3.3E-8 T 09-03-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module L21SP3_RS10905 f42ad2071cc24946706cd060b48dcd5e 557 SUPERFAMILY SSF49785 423 554 4.25E-7 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10905 f42ad2071cc24946706cd060b48dcd5e 557 Pfam PF04773 FecR protein 210 265 2.0E-5 T 09-03-2017 IPR006860 FecR protein L21SP3_RS09790 8540fe8426ce03ff5e38b349c516d430 505 SUPERFAMILY SSF52096 61 226 1.48E-19 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS09790 8540fe8426ce03ff5e38b349c516d430 505 SUPERFAMILY SSF52096 263 283 1.48E-19 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS09790 8540fe8426ce03ff5e38b349c516d430 505 Gene3D G3DSA:3.90.226.10 252 289 3.8E-14 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS09790 8540fe8426ce03ff5e38b349c516d430 505 Gene3D G3DSA:3.90.226.10 68 175 3.8E-14 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS01725 e299ad5195aa22120219a3bacf61ddc5 126 SUPERFAMILY SSF52172 3 122 3.27E-29 T 09-03-2017 IPR011006 CheY-like superfamily L21SP3_RS01725 e299ad5195aa22120219a3bacf61ddc5 126 Pfam PF00072 Response regulator receiver domain 4 117 2.6E-22 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS01725 e299ad5195aa22120219a3bacf61ddc5 126 SMART SM00448 2 117 9.0E-20 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 L21SP3_RS01725 e299ad5195aa22120219a3bacf61ddc5 126 Gene3D G3DSA:3.40.50.2300 3 123 1.3E-30 T 09-03-2017 L21SP3_RS07095 364636cb98f50e7089ea25481bc16fae 487 SUPERFAMILY SSF89095 305 411 3.66E-24 T 09-03-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 L21SP3_RS07095 364636cb98f50e7089ea25481bc16fae 487 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 4 485 1.0E-159 T 09-03-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 L21SP3_RS07095 364636cb98f50e7089ea25481bc16fae 487 SMART SM00845 336 485 2.1E-47 T 09-03-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 L21SP3_RS07095 364636cb98f50e7089ea25481bc16fae 487 Gene3D G3DSA:1.10.10.410 426 485 7.2E-7 T 09-03-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal L21SP3_RS07095 364636cb98f50e7089ea25481bc16fae 487 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 146 160 - T 09-03-2017 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 L21SP3_RS07095 364636cb98f50e7089ea25481bc16fae 487 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 5 486 34.319 T 09-03-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 L21SP3_RS07095 364636cb98f50e7089ea25481bc16fae 487 SUPERFAMILY SSF55931 8 304 5.1E-105 T 09-03-2017 L21SP3_RS07095 364636cb98f50e7089ea25481bc16fae 487 Pfam PF02637 GatB domain 336 485 3.9E-38 T 09-03-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 L21SP3_RS07095 364636cb98f50e7089ea25481bc16fae 487 Pfam PF02934 GatB/GatE catalytic domain 9 296 6.3E-104 T 09-03-2017 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 L21SP3_RS03475 34eba9c5f65e172385a8f7a28674bacb 336 Gene3D G3DSA:3.40.50.2000 176 266 1.8E-4 T 09-03-2017 L21SP3_RS03475 34eba9c5f65e172385a8f7a28674bacb 336 SUPERFAMILY SSF53756 116 274 1.73E-9 T 09-03-2017 L21SP3_RS00300 e6d89de926799a3468dd9bf284df8165 223 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 165 182 1.9E-6 T 09-03-2017 L21SP3_RS00300 e6d89de926799a3468dd9bf284df8165 223 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 183 202 1.9E-6 T 09-03-2017 L21SP3_RS00300 e6d89de926799a3468dd9bf284df8165 223 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 203 223 1.9E-6 T 09-03-2017 L21SP3_RS00300 e6d89de926799a3468dd9bf284df8165 223 Pfam PF00691 OmpA family 114 214 4.0E-22 T 09-03-2017 IPR006665 OmpA-like domain L21SP3_RS00300 e6d89de926799a3468dd9bf284df8165 223 SUPERFAMILY SSF103088 98 220 3.53E-30 T 09-03-2017 IPR006665 OmpA-like domain L21SP3_RS00300 e6d89de926799a3468dd9bf284df8165 223 Gene3D G3DSA:3.30.1330.60 96 220 2.6E-35 T 09-03-2017 IPR006665 OmpA-like domain L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 SMART SM01217 785 855 2.4E-29 T 09-03-2017 IPR026891 Fibronectin type III-like domain L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 SUPERFAMILY SSF52279 606 751 9.94E-48 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 SUPERFAMILY SSF52279 377 449 9.94E-48 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 Pfam PF07691 PA14 domain 470 599 2.8E-29 T 09-03-2017 IPR011658 PA14 domain L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 67 330 6.5E-50 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 Gene3D G3DSA:3.40.50.1700 606 751 2.9E-64 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 Gene3D G3DSA:3.40.50.1700 363 449 2.9E-64 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 SUPERFAMILY SSF51445 30 376 1.02E-93 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 Pfam PF14310 Fibronectin type III-like domain 785 855 2.5E-24 T 09-03-2017 IPR026891 Fibronectin type III-like domain L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 Gene3D G3DSA:3.20.20.300 30 348 6.4E-101 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 PRINTS PR00133 Glycosyl hydrolase family 3 signature 186 202 9.5E-13 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 PRINTS PR00133 Glycosyl hydrolase family 3 signature 256 274 9.5E-13 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 PRINTS PR00133 Glycosyl hydrolase family 3 signature 93 112 9.5E-13 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 SMART SM00758 470 605 6.5E-35 T 09-03-2017 IPR011658 PA14 domain L21SP3_RS10660 c867eca8c130ec7c7ba97a76c7d156de 867 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 377 748 7.0E-54 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 L21SP3_RS01145 495095047cddb9e6b483a842520e77cc 563 Gene3D G3DSA:3.10.580.10 418 524 2.0E-16 T 09-03-2017 L21SP3_RS01145 495095047cddb9e6b483a842520e77cc 563 SMART SM00116 428 476 1.3E-4 T 09-03-2017 IPR000644 CBS domain L21SP3_RS01145 495095047cddb9e6b483a842520e77cc 563 SMART SM00116 497 542 74.0 T 09-03-2017 IPR000644 CBS domain L21SP3_RS01145 495095047cddb9e6b483a842520e77cc 563 Pfam PF00571 CBS domain 421 470 1.8E-9 T 09-03-2017 IPR000644 CBS domain L21SP3_RS01145 495095047cddb9e6b483a842520e77cc 563 SUPERFAMILY SSF54631 416 531 5.63E-21 T 09-03-2017 L21SP3_RS01145 495095047cddb9e6b483a842520e77cc 563 Pfam PF00999 Sodium/hydrogen exchanger family 11 386 8.7E-33 T 09-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 L21SP3_RS10060 6951f8b3056918ae8e3d0d30129a372d 427 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 101 341 8.1E-51 T 09-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain L21SP3_RS10060 6951f8b3056918ae8e3d0d30129a372d 427 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 96 414 1.1E-44 T 09-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 L21SP3_RS10060 6951f8b3056918ae8e3d0d30129a372d 427 Gene3D G3DSA:2.40.50.100 236 267 1.2E-15 T 09-03-2017 L21SP3_RS10060 6951f8b3056918ae8e3d0d30129a372d 427 Gene3D G3DSA:2.40.50.100 119 151 1.2E-15 T 09-03-2017 L21SP3_RS10060 6951f8b3056918ae8e3d0d30129a372d 427 SUPERFAMILY SSF111369 112 345 7.19E-24 T 09-03-2017 L21SP3_RS06805 d325c0a3206c1a0a4b6e05832793b93b 381 Pfam PF00953 Glycosyl transferase family 4 107 298 2.9E-33 T 09-03-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 L21SP3_RS06805 d325c0a3206c1a0a4b6e05832793b93b 381 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 41 381 3.1E-93 T 09-03-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 L21SP3_RS06805 d325c0a3206c1a0a4b6e05832793b93b 381 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 27 379 20.967 T 09-03-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 L21SP3_RS06805 d325c0a3206c1a0a4b6e05832793b93b 381 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 73 85 2.0E-5 T 09-03-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 L21SP3_RS06805 d325c0a3206c1a0a4b6e05832793b93b 381 ProSitePatterns PS01347 MraY family signature 1. 73 85 - T 09-03-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 L21SP3_RS06805 d325c0a3206c1a0a4b6e05832793b93b 381 ProSitePatterns PS01348 MraY family signature 2. 197 208 - T 09-03-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 L21SP3_RS00645 79ce76ef7a1e1096115e48338a39fc5d 437 Gene3D G3DSA:2.30.40.10 10 77 3.1E-22 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP3_RS00645 79ce76ef7a1e1096115e48338a39fc5d 437 Pfam PF01979 Amidohydrolase family 59 430 8.0E-32 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 L21SP3_RS00645 79ce76ef7a1e1096115e48338a39fc5d 437 SUPERFAMILY SSF51338 9 62 2.0E-28 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP3_RS00645 79ce76ef7a1e1096115e48338a39fc5d 437 SUPERFAMILY SSF51338 377 434 2.0E-28 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 L21SP3_RS00645 79ce76ef7a1e1096115e48338a39fc5d 437 Hamap MF_00220_B Dihydroorotase [pyrC]. 9 435 41.346 T 09-03-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 L21SP3_RS00645 79ce76ef7a1e1096115e48338a39fc5d 437 Gene3D G3DSA:3.20.20.140 78 417 6.1E-106 T 09-03-2017 L21SP3_RS00645 79ce76ef7a1e1096115e48338a39fc5d 437 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 29 433 1.6E-130 T 09-03-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 L21SP3_RS00645 79ce76ef7a1e1096115e48338a39fc5d 437 SUPERFAMILY SSF51556 63 377 1.76E-100 T 09-03-2017 IPR032466 Metal-dependent hydrolase L21SP3_RS00645 79ce76ef7a1e1096115e48338a39fc5d 437 ProSitePatterns PS00482 Dihydroorotase signature 1. 66 74 - T 09-03-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 L21SP3_RS05665 849671b0190a66172c554ce64cf5d1b0 87 Gene3D G3DSA:1.10.287.1080 1 78 3.4E-21 T 09-03-2017 L21SP3_RS05665 849671b0190a66172c554ce64cf5d1b0 87 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 24 79 2.0E-9 T 09-03-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core L21SP3_RS05665 849671b0190a66172c554ce64cf5d1b0 87 SUPERFAMILY SSF101386 1 80 3.05E-17 T 09-03-2017 L21SP3_RS01700 11d8fc731660a92b105f735c86c0d98b 343 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 261 287 0.047 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS01700 11d8fc731660a92b105f735c86c0d98b 343 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 222 257 2.2E-7 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS01700 11d8fc731660a92b105f735c86c0d98b 343 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 146 179 2.9E-10 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS01700 11d8fc731660a92b105f735c86c0d98b 343 SUPERFAMILY SSF51161 40 315 1.03E-58 T 09-03-2017 IPR011004 Trimeric LpxA-like L21SP3_RS01700 11d8fc731660a92b105f735c86c0d98b 343 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 10 328 8.2E-87 T 09-03-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 L21SP3_RS01700 11d8fc731660a92b105f735c86c0d98b 343 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 27 88 1.4E-6 T 09-03-2017 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 L21SP3_RS01700 11d8fc731660a92b105f735c86c0d98b 343 Gene3D G3DSA:2.160.10.10 151 304 1.7E-37 T 09-03-2017 L21SP3_RS01700 11d8fc731660a92b105f735c86c0d98b 343 Gene3D G3DSA:2.160.10.10 99 150 3.3E-13 T 09-03-2017 L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 SUPERFAMILY SSF51735 9 252 1.23E-79 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 7.9E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 7.9E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 7.9E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.3E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.3E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.3E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.3E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.3E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.3E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 250 8.9E-59 T 09-03-2017 L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 6 253 2.1E-117 T 09-03-2017 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.12+1.1.1.127|MetaCyc: PWY-5515|MetaCyc: PWY-6507|MetaCyc: PWY-7562 L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 L21SP3_RS02180 6d108bad0e0a7db767f3d11f0f460bfa 253 Gene3D G3DSA:3.40.50.720 6 252 7.1E-85 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS11555 5e7ef0063c6b938baab419069511a4d2 207 Hamap MF_00017 Recombination protein RecR [recR]. 1 206 81.458 T 09-03-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 L21SP3_RS11555 5e7ef0063c6b938baab419069511a4d2 207 SMART SM00493 88 173 2.2E-12 T 09-03-2017 IPR006171 Toprim domain L21SP3_RS11555 5e7ef0063c6b938baab419069511a4d2 207 ProSitePatterns PS01300 RecR protein signature. 65 86 - T 09-03-2017 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 L21SP3_RS11555 5e7ef0063c6b938baab419069511a4d2 207 Pfam PF02132 RecR protein 47 86 2.5E-14 T 09-03-2017 IPR023628 Recombination protein RecR, C4-type zinc finger L21SP3_RS11555 5e7ef0063c6b938baab419069511a4d2 207 TIGRFAM TIGR00615 recR: recombination protein RecR 11 203 1.2E-70 T 09-03-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 L21SP3_RS11555 5e7ef0063c6b938baab419069511a4d2 207 SUPERFAMILY SSF111304 11 206 7.59E-66 T 09-03-2017 IPR023627 Recombination protein RecR L21SP3_RS11555 5e7ef0063c6b938baab419069511a4d2 207 Pfam PF13662 Toprim domain 88 179 2.9E-22 T 09-03-2017 IPR006171 Toprim domain L21SP3_RS07455 bc4f9769462214c44a7a52ad84641232 138 Pfam PF00226 DnaJ domain 23 74 3.7E-15 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS07455 bc4f9769462214c44a7a52ad84641232 138 SUPERFAMILY SSF46565 19 72 7.59E-15 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS07455 bc4f9769462214c44a7a52ad84641232 138 Gene3D G3DSA:1.10.287.110 22 72 3.0E-15 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS07455 bc4f9769462214c44a7a52ad84641232 138 PRINTS PR00625 DnaJ domain signature 22 40 2.1E-11 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS07455 bc4f9769462214c44a7a52ad84641232 138 PRINTS PR00625 DnaJ domain signature 57 77 2.1E-11 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS07455 bc4f9769462214c44a7a52ad84641232 138 PRINTS PR00625 DnaJ domain signature 40 55 2.1E-11 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS07455 bc4f9769462214c44a7a52ad84641232 138 SMART SM00271 19 77 3.5E-11 T 09-03-2017 IPR001623 DnaJ domain L21SP3_RS08600 a7917ad551e38582a4da75ee30dbea60 346 PIRSF PIRSF006268 1 339 2.9E-84 T 09-03-2017 IPR024932 Flavin transferase ApbE GO:0017013 L21SP3_RS08600 a7917ad551e38582a4da75ee30dbea60 346 Pfam PF02424 ApbE family 39 316 5.6E-73 T 09-03-2017 IPR024932 Flavin transferase ApbE GO:0017013 L21SP3_RS08600 a7917ad551e38582a4da75ee30dbea60 346 SUPERFAMILY SSF143631 35 335 1.06E-81 T 09-03-2017 IPR003374 ApbE-like domain L21SP3_RS04885 0052113a79dc387d6a7493ee94c1c76d 137 SUPERFAMILY SSF81593 14 105 3.92E-12 T 09-03-2017 L21SP3_RS04885 0052113a79dc387d6a7493ee94c1c76d 137 Pfam PF05168 HEPN domain 12 121 2.4E-16 T 09-03-2017 IPR007842 HEPN domain L21SP3_RS04885 0052113a79dc387d6a7493ee94c1c76d 137 Gene3D G3DSA:1.20.120.330 11 122 3.4E-17 T 09-03-2017 L21SP3_RS04885 0052113a79dc387d6a7493ee94c1c76d 137 SMART SM00748 16 124 3.8E-4 T 09-03-2017 IPR007842 HEPN domain L21SP3_RS10565 1ce1ec6278605855d4b203bb07f36822 426 Gene3D G3DSA:2.115.10.20 130 424 1.3E-81 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS10565 1ce1ec6278605855d4b203bb07f36822 426 Gene3D G3DSA:2.60.120.260 10 87 5.7E-4 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10565 1ce1ec6278605855d4b203bb07f36822 426 SUPERFAMILY SSF49785 12 82 4.42E-6 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS10565 1ce1ec6278605855d4b203bb07f36822 426 Pfam PF04616 Glycosyl hydrolases family 43 130 408 7.4E-54 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS10565 1ce1ec6278605855d4b203bb07f36822 426 SUPERFAMILY SSF75005 130 421 4.83E-72 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS03700 62e4cf838373007712d2ccb1f3860262 381 Gene3D G3DSA:3.40.720.10 7 256 6.7E-17 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS03700 62e4cf838373007712d2ccb1f3860262 381 SUPERFAMILY SSF53649 10 121 5.79E-26 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS03700 62e4cf838373007712d2ccb1f3860262 381 SUPERFAMILY SSF53649 163 353 5.79E-26 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS03700 62e4cf838373007712d2ccb1f3860262 381 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 44 255 1.3E-12 T 09-03-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 L21SP3_RS08670 bcaac9178a026eb6de8c9cdc9966b559 130 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 4 116 5.8E-39 T 09-03-2017 IPR018745 Domain of unknown function DUF2294 L21SP3_RS09055 7e3019c5bcf196190ad833be70021a71 170 Gene3D G3DSA:3.40.50.150 30 146 3.9E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS09055 7e3019c5bcf196190ad833be70021a71 170 Pfam PF08241 Methyltransferase domain 53 109 4.0E-12 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 L21SP3_RS09055 7e3019c5bcf196190ad833be70021a71 170 SUPERFAMILY SSF53335 29 146 9.47E-21 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS03710 feab33b8060cd51b6f6a8e385eabf271 204 SUPERFAMILY SSF52540 4 189 6.53E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03710 feab33b8060cd51b6f6a8e385eabf271 204 PRINTS PR00988 Uridine kinase signature 146 157 1.2E-26 T 09-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 L21SP3_RS03710 feab33b8060cd51b6f6a8e385eabf271 204 PRINTS PR00988 Uridine kinase signature 168 181 1.2E-26 T 09-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 L21SP3_RS03710 feab33b8060cd51b6f6a8e385eabf271 204 PRINTS PR00988 Uridine kinase signature 132 142 1.2E-26 T 09-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 L21SP3_RS03710 feab33b8060cd51b6f6a8e385eabf271 204 PRINTS PR00988 Uridine kinase signature 31 42 1.2E-26 T 09-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 L21SP3_RS03710 feab33b8060cd51b6f6a8e385eabf271 204 PRINTS PR00988 Uridine kinase signature 2 19 1.2E-26 T 09-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 L21SP3_RS03710 feab33b8060cd51b6f6a8e385eabf271 204 PRINTS PR00988 Uridine kinase signature 76 91 1.2E-26 T 09-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 L21SP3_RS03710 feab33b8060cd51b6f6a8e385eabf271 204 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 5 181 1.8E-34 T 09-03-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 L21SP3_RS03710 feab33b8060cd51b6f6a8e385eabf271 204 Gene3D G3DSA:3.40.50.300 4 200 3.6E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03165 1e51a30e7b20f19c5711c732716f2ae2 780 Pfam PF16990 Carbohydrate binding module (family 35) 656 778 9.7E-13 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 L21SP3_RS03165 1e51a30e7b20f19c5711c732716f2ae2 780 Pfam PF13199 Glycosyl hydrolase family 66 75 643 1.1E-136 T 09-03-2017 IPR025092 Glycosyl hydrolase family 66 L21SP3_RS03165 1e51a30e7b20f19c5711c732716f2ae2 780 Gene3D G3DSA:2.60.120.260 656 776 7.4E-19 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS03165 1e51a30e7b20f19c5711c732716f2ae2 780 SUPERFAMILY SSF49785 654 776 8.41E-18 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS06200 894a6298efd8bc64818e8ce745b5ef35 92 Pfam PF00276 Ribosomal protein L23 5 90 5.5E-33 T 09-03-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06200 894a6298efd8bc64818e8ce745b5ef35 92 Gene3D G3DSA:3.30.70.330 2 92 7.9E-33 T 09-03-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 L21SP3_RS06200 894a6298efd8bc64818e8ce745b5ef35 92 SUPERFAMILY SSF54189 3 91 3.13E-30 T 09-03-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06200 894a6298efd8bc64818e8ce745b5ef35 92 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 92 17.733 T 09-03-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 L21SP3_RS02535 ab3419f64e451fdfb21b6801a95f141a 474 SUPERFAMILY SSF53448 7 447 5.85E-132 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS02535 ab3419f64e451fdfb21b6801a95f141a 474 Pfam PF01704 UTP--glucose-1-phosphate uridylyltransferase 102 403 8.3E-40 T 09-03-2017 IPR002618 UDPGP family GO:0008152|GO:0070569 L21SP3_RS02535 ab3419f64e451fdfb21b6801a95f141a 474 Gene3D G3DSA:3.90.550.10 6 427 1.2E-134 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS04825 0a63fd39dc51c902c71632029d743301 415 SUPERFAMILY SSF53756 85 403 6.28E-24 T 09-03-2017 L21SP3_RS04825 0a63fd39dc51c902c71632029d743301 415 Pfam PF00534 Glycosyl transferases group 1 218 382 2.0E-15 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS06310 276fb064f02609fe3b1915c89267c5a0 582 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 397 411 - T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS06310 276fb064f02609fe3b1915c89267c5a0 582 Gene3D G3DSA:3.30.450.90 180 302 2.7E-48 T 09-03-2017 L21SP3_RS06310 276fb064f02609fe3b1915c89267c5a0 582 SUPERFAMILY SSF160246 14 153 2.25E-27 T 09-03-2017 L21SP3_RS06310 276fb064f02609fe3b1915c89267c5a0 582 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 50 157 3.2E-19 T 09-03-2017 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 L21SP3_RS06310 276fb064f02609fe3b1915c89267c5a0 582 SUPERFAMILY SSF52540 189 575 1.37E-97 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06310 276fb064f02609fe3b1915c89267c5a0 582 Gene3D G3DSA:3.40.50.300 309 577 2.8E-93 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06310 276fb064f02609fe3b1915c89267c5a0 582 Pfam PF00437 Type II/IV secretion system protein 204 469 2.3E-77 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS05720 4ad47016406e2ba2e2d5dbeff7287382 349 SUPERFAMILY SSF74650 8 347 9.42E-119 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP3_RS05720 4ad47016406e2ba2e2d5dbeff7287382 349 Gene3D G3DSA:2.70.98.10 11 348 1.6E-137 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS05720 4ad47016406e2ba2e2d5dbeff7287382 349 Pfam PF01263 Aldose 1-epimerase 19 345 5.6E-92 T 09-03-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 L21SP3_RS05720 4ad47016406e2ba2e2d5dbeff7287382 349 PIRSF PIRSF005096 2 349 5.2E-130 T 09-03-2017 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 L21SP3_RS10780 8f4da9c59a524a92bb393e47bfa93611 176 SUPERFAMILY SSF160369 5 171 2.09E-35 T 09-03-2017 L21SP3_RS10780 8f4da9c59a524a92bb393e47bfa93611 176 Pfam PF00466 Ribosomal protein L10 5 98 1.4E-13 T 09-03-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 L21SP3_RS06630 e03235d1f9bad17371914a18e77ee4bf 201 PRINTS PR00127 Clp protease catalytic subunit P signature 93 110 2.3E-44 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP3_RS06630 e03235d1f9bad17371914a18e77ee4bf 201 PRINTS PR00127 Clp protease catalytic subunit P signature 173 192 2.3E-44 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP3_RS06630 e03235d1f9bad17371914a18e77ee4bf 201 PRINTS PR00127 Clp protease catalytic subunit P signature 114 133 2.3E-44 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP3_RS06630 e03235d1f9bad17371914a18e77ee4bf 201 PRINTS PR00127 Clp protease catalytic subunit P signature 22 37 2.3E-44 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP3_RS06630 e03235d1f9bad17371914a18e77ee4bf 201 PRINTS PR00127 Clp protease catalytic subunit P signature 62 82 2.3E-44 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP3_RS06630 e03235d1f9bad17371914a18e77ee4bf 201 SUPERFAMILY SSF52096 15 199 2.65E-64 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS06630 e03235d1f9bad17371914a18e77ee4bf 201 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 115 128 - T 09-03-2017 IPR033135 ClpP, histidine active site L21SP3_RS06630 e03235d1f9bad17371914a18e77ee4bf 201 Pfam PF00574 Clp protease 16 197 1.3E-74 T 09-03-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA L21SP3_RS06630 e03235d1f9bad17371914a18e77ee4bf 201 Gene3D G3DSA:3.90.226.10 6 198 3.5E-77 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS06630 e03235d1f9bad17371914a18e77ee4bf 201 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 93 104 - T 09-03-2017 IPR018215 ClpP, Ser active site L21SP3_RS06630 e03235d1f9bad17371914a18e77ee4bf 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 6 198 40.691 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 L21SP3_RS01790 39ee0e7450bac3addd29fe0af7a30f81 124 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 3 115 27.475 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS01790 39ee0e7450bac3addd29fe0af7a30f81 124 PRINTS PR00061 Ribosomal protein L19 signature 35 64 1.9E-37 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS01790 39ee0e7450bac3addd29fe0af7a30f81 124 PRINTS PR00061 Ribosomal protein L19 signature 5 34 1.9E-37 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS01790 39ee0e7450bac3addd29fe0af7a30f81 124 PRINTS PR00061 Ribosomal protein L19 signature 89 114 1.9E-37 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS01790 39ee0e7450bac3addd29fe0af7a30f81 124 SUPERFAMILY SSF50104 4 117 3.31E-40 T 09-03-2017 IPR008991 Translation protein SH3-like domain L21SP3_RS01790 39ee0e7450bac3addd29fe0af7a30f81 124 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 4 114 7.3E-41 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS01790 39ee0e7450bac3addd29fe0af7a30f81 124 PIRSF PIRSF002191 1 124 7.7E-47 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS01790 39ee0e7450bac3addd29fe0af7a30f81 124 Pfam PF01245 Ribosomal protein L19 5 114 8.0E-44 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS04995 15b8b042fcdc04b257bf82421479f1d1 55 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 3 54 6.1E-10 T 09-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP3_RS04995 15b8b042fcdc04b257bf82421479f1d1 55 SUPERFAMILY SSF53323 2 55 1.83E-10 T 09-03-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 L21SP3_RS04995 15b8b042fcdc04b257bf82421479f1d1 55 Gene3D G3DSA:3.40.920.10 2 54 2.0E-8 T 09-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP3_RS06015 ecba907127586c888679a78490e5680a 377 Pfam PF01032 FecCD transport family 54 368 1.6E-87 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 L21SP3_RS06015 ecba907127586c888679a78490e5680a 377 SUPERFAMILY SSF81345 40 368 3.01E-77 T 09-03-2017 IPR029022 ABC transporter, BtuC-like L21SP3_RS06015 ecba907127586c888679a78490e5680a 377 Gene3D G3DSA:1.10.3470.10 40 372 2.2E-97 T 09-03-2017 IPR029022 ABC transporter, BtuC-like L21SP3_RS09720 fdd7fb09f221a68d4e9ad5680024c7f7 524 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 4 432 5.0E-36 T 09-03-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 L21SP3_RS09720 fdd7fb09f221a68d4e9ad5680024c7f7 524 Gene3D G3DSA:3.40.720.10 2 300 5.4E-43 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS09720 fdd7fb09f221a68d4e9ad5680024c7f7 524 SUPERFAMILY SSF53649 331 473 1.01E-36 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09720 fdd7fb09f221a68d4e9ad5680024c7f7 524 SUPERFAMILY SSF53649 3 294 1.01E-36 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09810 1ed5ff6af46d65fa9b542833bc4fea04 540 Pfam PF01609 Transposase DDE domain 200 470 2.2E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS09810 1ed5ff6af46d65fa9b542833bc4fea04 540 SUPERFAMILY SSF53098 160 516 7.59E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS07360 d942cb6782008b3ddd11818414aef0b2 115 Gene3D G3DSA:2.60.120.10 28 110 9.5E-18 T 09-03-2017 IPR014710 RmlC-like jelly roll fold L21SP3_RS07360 d942cb6782008b3ddd11818414aef0b2 115 SUPERFAMILY SSF51182 17 106 4.82E-18 T 09-03-2017 IPR011051 RmlC-like cupin domain L21SP3_RS07360 d942cb6782008b3ddd11818414aef0b2 115 Pfam PF07883 Cupin domain 33 101 1.6E-11 T 09-03-2017 IPR013096 Cupin 2, conserved barrel L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 240 382 1.1E-61 T 09-03-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 8 107 3.8E-36 T 09-03-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 Gene3D G3DSA:3.30.300.10 15 140 2.7E-38 T 09-03-2017 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 Gene3D G3DSA:3.30.300.10 235 265 8.3E-20 T 09-03-2017 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 Gene3D G3DSA:3.30.300.10 266 387 3.4E-58 T 09-03-2017 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 SUPERFAMILY SSF55973 121 239 1.3E-41 T 09-03-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 9 392 4.2E-154 T 09-03-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 6 393 49.115 T 09-03-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 Gene3D G3DSA:3.30.300.10 141 234 1.4E-31 T 09-03-2017 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 PIRSF PIRSF000497 2 393 7.9E-157 T 09-03-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 124 134 - T 09-03-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 Pfam PF02772 S-adenosylmethionine synthetase, central domain 122 238 3.2E-39 T 09-03-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 266 274 - T 09-03-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 SUPERFAMILY SSF55973 240 392 1.92E-61 T 09-03-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 L21SP3_RS04940 e5a590a187716e6cdc001b3ad571b544 393 SUPERFAMILY SSF55973 8 116 5.3E-40 T 09-03-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 L21SP3_RS06205 8317736200e5099628f8b409d01f10cd 205 SUPERFAMILY SSF52166 1 203 1.57E-60 T 09-03-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06205 8317736200e5099628f8b409d01f10cd 205 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 202 1.3E-58 T 09-03-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06205 8317736200e5099628f8b409d01f10cd 205 Pfam PF00573 Ribosomal protein L4/L1 family 17 202 5.1E-55 T 09-03-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 L21SP3_RS06205 8317736200e5099628f8b409d01f10cd 205 Gene3D G3DSA:3.40.1370.10 58 202 1.1E-43 T 09-03-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 L21SP3_RS04090 de92eb1b1fcba954f72ed3233b6b0642 432 SUPERFAMILY SSF53649 255 406 1.96E-14 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS04090 de92eb1b1fcba954f72ed3233b6b0642 432 Pfam PF07394 Protein of unknown function (DUF1501) 37 413 6.2E-93 T 09-03-2017 IPR010869 Protein of unknown function DUF1501 L21SP3_RS05030 2db027a6a6be41deca2884deaefa5edc 399 Gene3D G3DSA:3.40.50.1100 182 397 2.1E-85 T 09-03-2017 L21SP3_RS05030 2db027a6a6be41deca2884deaefa5edc 399 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 8 397 48.192 T 09-03-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 L21SP3_RS05030 2db027a6a6be41deca2884deaefa5edc 399 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 13 396 4.2E-165 T 09-03-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 L21SP3_RS05030 2db027a6a6be41deca2884deaefa5edc 399 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 87 101 - T 09-03-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 L21SP3_RS05030 2db027a6a6be41deca2884deaefa5edc 399 Gene3D G3DSA:3.40.50.1100 105 181 9.9E-15 T 09-03-2017 L21SP3_RS05030 2db027a6a6be41deca2884deaefa5edc 399 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 59 384 3.6E-44 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP3_RS05030 2db027a6a6be41deca2884deaefa5edc 399 SUPERFAMILY SSF53686 9 395 1.31E-133 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme L21SP3_RS05030 2db027a6a6be41deca2884deaefa5edc 399 PIRSF PIRSF001413 4 399 1.4E-156 T 09-03-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 L21SP3_RS04760 37158a728edd1a8e83cbe6068cf8def7 394 SUPERFAMILY SSF53383 17 197 1.55E-70 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS04760 37158a728edd1a8e83cbe6068cf8def7 394 SUPERFAMILY SSF53383 248 389 1.55E-70 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS04760 37158a728edd1a8e83cbe6068cf8def7 394 Gene3D G3DSA:3.40.640.10 13 185 1.7E-56 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS04760 37158a728edd1a8e83cbe6068cf8def7 394 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 12 186 4.2E-53 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP3_RS04760 37158a728edd1a8e83cbe6068cf8def7 394 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 227 383 9.0E-15 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP3_RS04760 37158a728edd1a8e83cbe6068cf8def7 394 PIRSF PIRSF000390 7 393 3.7E-70 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP3_RS04760 37158a728edd1a8e83cbe6068cf8def7 394 Gene3D G3DSA:3.90.1150.10 268 391 2.8E-14 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS08845 073569925214b9703ab7c07f879cd7c6 505 Gene3D G3DSA:3.30.1120.10 428 500 7.4E-10 T 09-03-2017 L21SP3_RS08845 073569925214b9703ab7c07f879cd7c6 505 SUPERFAMILY SSF53649 37 492 3.53E-101 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS08845 073569925214b9703ab7c07f879cd7c6 505 Gene3D G3DSA:3.40.720.10 36 399 4.0E-86 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS08845 073569925214b9703ab7c07f879cd7c6 505 Pfam PF00884 Sulfatase 38 396 6.3E-56 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS01090 c9332825d0c6fe833ce6e62cd4581b4c 370 SUPERFAMILY SSF109604 14 363 6.52E-75 T 09-03-2017 L21SP3_RS01090 c9332825d0c6fe833ce6e62cd4581b4c 370 Pfam PF01966 HD domain 61 185 3.0E-13 T 09-03-2017 IPR006674 HD domain L21SP3_RS01090 c9332825d0c6fe833ce6e62cd4581b4c 370 SMART SM00471 57 196 6.3E-13 T 09-03-2017 IPR003607 HD/PDEase domain L21SP3_RS01090 c9332825d0c6fe833ce6e62cd4581b4c 370 Pfam PF13286 Phosphohydrolase-associated domain 277 360 3.2E-17 T 09-03-2017 IPR026875 Phosphohydrolase-associated domain L21SP3_RS01090 c9332825d0c6fe833ce6e62cd4581b4c 370 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 24 158 8.1E-55 T 09-03-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 L21SP3_RS01090 c9332825d0c6fe833ce6e62cd4581b4c 370 Gene3D G3DSA:1.10.3210.10 268 366 1.3E-70 T 09-03-2017 IPR006674 HD domain L21SP3_RS01090 c9332825d0c6fe833ce6e62cd4581b4c 370 Gene3D G3DSA:1.10.3210.10 20 211 1.3E-70 T 09-03-2017 IPR006674 HD domain L21SP3_RS01090 c9332825d0c6fe833ce6e62cd4581b4c 370 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 1 363 32.138 T 09-03-2017 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 L21SP3_RS07500 c26b8db172c37b37eb1bb47cbf8e181b 545 Gene3D G3DSA:3.30.1120.10 455 519 3.1E-10 T 09-03-2017 L21SP3_RS07500 c26b8db172c37b37eb1bb47cbf8e181b 545 Pfam PF00884 Sulfatase 53 404 1.0E-57 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS07500 c26b8db172c37b37eb1bb47cbf8e181b 545 SUPERFAMILY SSF53649 51 517 1.11E-110 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS07500 c26b8db172c37b37eb1bb47cbf8e181b 545 Gene3D G3DSA:3.40.720.10 50 409 3.0E-96 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS07500 c26b8db172c37b37eb1bb47cbf8e181b 545 ProSitePatterns PS00523 Sulfatases signature 1. 99 111 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS08750 cf3b50fd9cd6e4371d406c8ad9ce0b2c 326 Gene3D G3DSA:3.40.50.1820 28 318 5.7E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS08750 cf3b50fd9cd6e4371d406c8ad9ce0b2c 326 SUPERFAMILY SSF53474 40 307 1.01E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS05130 ba75a84c6401d776e8e37c958822d2a0 252 Gene3D G3DSA:3.40.50.880 8 250 1.4E-50 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS05130 ba75a84c6401d776e8e37c958822d2a0 252 SUPERFAMILY SSF52317 7 251 3.89E-29 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS05130 ba75a84c6401d776e8e37c958822d2a0 252 Pfam PF07090 Putative glutamine amidotransferase 58 217 3.0E-24 T 09-03-2017 IPR010768 Putative glutamine amidotransferase L21SP3_RS04620 baf50ec0117a27b65b0b3ebb46f273ce 386 Pfam PF04055 Radical SAM superfamily 64 235 1.4E-9 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS04620 baf50ec0117a27b65b0b3ebb46f273ce 386 SUPERFAMILY SSF102114 62 251 2.62E-16 T 09-03-2017 L21SP3_RS04620 baf50ec0117a27b65b0b3ebb46f273ce 386 SUPERFAMILY SSF47781 302 378 8.15E-12 T 09-03-2017 IPR010994 RuvA domain 2-like L21SP3_RS04620 baf50ec0117a27b65b0b3ebb46f273ce 386 Gene3D G3DSA:1.10.150.280 322 370 1.9E-10 T 09-03-2017 L21SP3_RS04620 baf50ec0117a27b65b0b3ebb46f273ce 386 Gene3D G3DSA:3.20.20.70 63 245 2.6E-13 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS04620 baf50ec0117a27b65b0b3ebb46f273ce 386 Pfam PF12836 Helix-hairpin-helix motif 322 361 2.6E-8 T 09-03-2017 L21SP3_RS04270 9bf3f8e9f8bec77f2375ec83090f067e 223 Gene3D G3DSA:1.25.40.10 124 183 2.0E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS07590 189201471f8170c95a2f187087bfa236 605 Gene3D G3DSA:3.80.30.20 305 538 1.1E-33 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe L21SP3_RS07590 189201471f8170c95a2f187087bfa236 605 SUPERFAMILY SSF102114 309 368 1.39E-9 T 09-03-2017 L21SP3_RS07590 189201471f8170c95a2f187087bfa236 605 SUPERFAMILY SSF102114 395 522 1.39E-9 T 09-03-2017 L21SP3_RS07590 189201471f8170c95a2f187087bfa236 605 SMART SM00729 305 554 1.2E-4 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP3_RS07590 189201471f8170c95a2f187087bfa236 605 Pfam PF11842 Domain of unknown function (DUF3362) 523 583 1.2E-8 T 09-03-2017 IPR024560 Uncharacterised protein family UPF0313, C-terminal L21SP3_RS07590 189201471f8170c95a2f187087bfa236 605 Pfam PF08497 Radical SAM N-terminal 12 308 1.1E-110 T 09-03-2017 IPR013704 Uncharacterised protein family UPF0313, N-terminal L21SP3_RS07590 189201471f8170c95a2f187087bfa236 605 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 12 566 2.9E-215 T 09-03-2017 IPR022946 Uncharacterised protein family UPF0313 L21SP3_RS07590 189201471f8170c95a2f187087bfa236 605 Pfam PF04055 Radical SAM superfamily 310 511 1.2E-12 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS07590 189201471f8170c95a2f187087bfa236 605 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 309 329 - T 09-03-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 L21SP3_RS01965 a7fa8a9bb533d76ba642919ddf11e08d 1080 SUPERFAMILY SSF49785 15 71 1.84E-32 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01965 a7fa8a9bb533d76ba642919ddf11e08d 1080 SUPERFAMILY SSF49785 109 217 1.84E-32 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01965 a7fa8a9bb533d76ba642919ddf11e08d 1080 Gene3D G3DSA:2.60.120.260 17 210 4.7E-35 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01965 a7fa8a9bb533d76ba642919ddf11e08d 1080 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 23 214 7.4E-17 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS01965 a7fa8a9bb533d76ba642919ddf11e08d 1080 Gene3D G3DSA:2.60.40.320 211 330 1.5E-8 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS01965 a7fa8a9bb533d76ba642919ddf11e08d 1080 Pfam PF00703 Glycosyl hydrolases family 2 219 332 1.1E-7 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS01965 a7fa8a9bb533d76ba642919ddf11e08d 1080 Gene3D G3DSA:2.60.120.260 949 1076 7.0E-32 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01965 a7fa8a9bb533d76ba642919ddf11e08d 1080 SUPERFAMILY SSF51445 329 633 1.94E-40 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS01965 a7fa8a9bb533d76ba642919ddf11e08d 1080 Gene3D G3DSA:3.20.20.80 331 641 1.2E-28 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS01965 a7fa8a9bb533d76ba642919ddf11e08d 1080 SUPERFAMILY SSF49785 941 1075 1.49E-29 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS01965 a7fa8a9bb533d76ba642919ddf11e08d 1080 Pfam PF00754 F5/8 type C domain 950 1073 4.3E-24 T 09-03-2017 IPR000421 Coagulation factor 5/8 C-terminal domain L21SP3_RS08425 34209a5de217c27e56215afc8b20af27 663 Pfam PF09605 Hypothetical bacterial integral membrane protein (Trep_Strep) 490 611 9.1E-11 T 09-03-2017 IPR011733 Conserved hypothetical CHP02185, integral membrane L21SP3_RS08425 34209a5de217c27e56215afc8b20af27 663 SUPERFAMILY SSF102114 53 443 1.83E-82 T 09-03-2017 L21SP3_RS08425 34209a5de217c27e56215afc8b20af27 663 SMART SM00729 68 288 6.6E-45 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 L21SP3_RS08425 34209a5de217c27e56215afc8b20af27 663 Gene3D G3DSA:3.80.30.20 68 274 3.5E-33 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe L21SP3_RS08425 34209a5de217c27e56215afc8b20af27 663 Pfam PF04055 Radical SAM superfamily 73 244 9.3E-19 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 L21SP3_RS03555 30187e468d666c64e0dd059a1c82116f 249 Gene3D G3DSA:3.40.470.10 60 244 2.1E-66 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 L21SP3_RS03555 30187e468d666c64e0dd059a1c82116f 249 SMART SM00987 85 239 2.2E-37 T 09-03-2017 L21SP3_RS03555 30187e468d666c64e0dd059a1c82116f 249 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 71 242 3.3E-62 T 09-03-2017 IPR005273 Uracil-DNA glycosylase, family 4 domain L21SP3_RS03555 30187e468d666c64e0dd059a1c82116f 249 Pfam PF03167 Uracil DNA glycosylase superfamily 85 238 1.1E-45 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 L21SP3_RS03555 30187e468d666c64e0dd059a1c82116f 249 SUPERFAMILY SSF52141 57 243 1.14E-60 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 L21SP3_RS03555 30187e468d666c64e0dd059a1c82116f 249 SMART SM00986 85 239 2.2E-37 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 L21SP3_RS07380 4542072b440eb6672e4e105695e2ebdd 269 Gene3D G3DSA:3.40.50.300 7 247 7.2E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07380 4542072b440eb6672e4e105695e2ebdd 269 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS07380 4542072b440eb6672e4e105695e2ebdd 269 Pfam PF00005 ABC transporter 22 176 4.5E-34 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS07380 4542072b440eb6672e4e105695e2ebdd 269 SUPERFAMILY SSF52540 7 240 6.52E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07380 4542072b440eb6672e4e105695e2ebdd 269 SMART SM00382 31 225 1.1E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS05095 cec1a1265dce52a99ce026a29cb25dd9 88 Gene3D G3DSA:1.10.10.60 17 84 3.7E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS05095 cec1a1265dce52a99ce026a29cb25dd9 88 SUPERFAMILY SSF46689 1 82 3.05E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS05095 cec1a1265dce52a99ce026a29cb25dd9 88 Pfam PF01527 Transposase 2 71 1.7E-18 T 09-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 L21SP3_RS07905 bfce137e139d3e838fc945273c6ca795 129 Gene3D G3DSA:1.10.10.10 26 73 2.0E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS07905 bfce137e139d3e838fc945273c6ca795 129 SUPERFAMILY SSF88659 18 73 2.99E-6 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03605 89947975e0ab9a4a4b3a44cb496b9ade 348 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 339 1.5E-48 T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 L21SP3_RS03605 89947975e0ab9a4a4b3a44cb496b9ade 348 SUPERFAMILY SSF51726 6 342 8.37E-44 T 09-03-2017 L21SP3_RS03605 89947975e0ab9a4a4b3a44cb496b9ade 348 Gene3D G3DSA:3.20.20.210 9 340 1.1E-47 T 09-03-2017 L21SP3_RS04300 49e2852db88c0c1d44dd1d785112ac91 101 Gene3D G3DSA:1.10.260.40 8 86 2.0E-26 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS04300 49e2852db88c0c1d44dd1d785112ac91 101 SUPERFAMILY SSF47413 12 89 4.38E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS04300 49e2852db88c0c1d44dd1d785112ac91 101 Pfam PF01381 Helix-turn-helix 21 69 5.9E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 L21SP3_RS04300 49e2852db88c0c1d44dd1d785112ac91 101 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 9 86 2.5E-24 T 09-03-2017 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 L21SP3_RS01750 022537324bd3a2e2891227b0e85879ef 322 Pfam PF04015 Domain of unknown function (DUF362) 90 285 2.1E-29 T 09-03-2017 IPR007160 Domain of unknown function DUF362 L21SP3_RS03520 3eba6f0c8ec5efb46977ab5273dbbfa9 332 SUPERFAMILY SSF48371 93 278 1.55E-14 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 L21SP3_RS03520 3eba6f0c8ec5efb46977ab5273dbbfa9 332 Gene3D G3DSA:1.25.10.10 48 278 1.5E-13 T 09-03-2017 IPR011989 Armadillo-like helical L21SP3_RS01475 e8fd502e972aab26bbdc70bed7cfe391 204 Pfam PF13036 Peptidoglycan-synthase activator LpoB 11 190 5.7E-43 T 09-03-2017 IPR014094 Penicillin-binding protein activator LpoB L21SP3_RS01475 e8fd502e972aab26bbdc70bed7cfe391 204 TIGRFAM TIGR02722 lp_: uncharacterized lipoprotein 7 190 9.5E-39 T 09-03-2017 IPR014094 Penicillin-binding protein activator LpoB L21SP3_RS01920 3ffb317d5a3638634ade49ca5cb6bf2e 467 PRINTS PR00171 Sugar transporter signature 366 387 3.9E-21 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS01920 3ffb317d5a3638634ade49ca5cb6bf2e 467 PRINTS PR00171 Sugar transporter signature 109 128 3.9E-21 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS01920 3ffb317d5a3638634ade49ca5cb6bf2e 467 PRINTS PR00171 Sugar transporter signature 389 401 3.9E-21 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS01920 3ffb317d5a3638634ade49ca5cb6bf2e 467 PRINTS PR00171 Sugar transporter signature 281 291 3.9E-21 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS01920 3ffb317d5a3638634ade49ca5cb6bf2e 467 PRINTS PR00171 Sugar transporter signature 25 35 3.9E-21 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS01920 3ffb317d5a3638634ade49ca5cb6bf2e 467 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 9 461 4.5E-112 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS01920 3ffb317d5a3638634ade49ca5cb6bf2e 467 Gene3D G3DSA:1.20.1250.20 272 463 8.3E-25 T 09-03-2017 L21SP3_RS01920 3ffb317d5a3638634ade49ca5cb6bf2e 467 Gene3D G3DSA:1.20.1250.20 20 220 9.5E-25 T 09-03-2017 L21SP3_RS01920 3ffb317d5a3638634ade49ca5cb6bf2e 467 ProSitePatterns PS00216 Sugar transport proteins signature 1. 325 342 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP3_RS01920 3ffb317d5a3638634ade49ca5cb6bf2e 467 Pfam PF00083 Sugar (and other) transporter 19 463 5.6E-114 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 L21SP3_RS01920 3ffb317d5a3638634ade49ca5cb6bf2e 467 SUPERFAMILY SSF103473 6 463 1.07E-73 T 09-03-2017 IPR020846 Major facilitator superfamily domain L21SP3_RS01920 3ffb317d5a3638634ade49ca5cb6bf2e 467 ProSitePatterns PS00216 Sugar transport proteins signature 1. 72 89 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP3_RS01920 3ffb317d5a3638634ade49ca5cb6bf2e 467 ProSitePatterns PS00217 Sugar transport proteins signature 2. 114 139 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP3_RS01985 8df28bface6b683a61060dbcdedc3b3f 171 Gene3D G3DSA:3.40.50.300 29 148 9.8E-25 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01985 8df28bface6b683a61060dbcdedc3b3f 171 Pfam PF00005 ABC transporter 17 82 1.9E-6 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS01985 8df28bface6b683a61060dbcdedc3b3f 171 SUPERFAMILY SSF52540 43 144 1.33E-25 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09045 cd301242e518f61bd3dc3483f99894c4 382 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 295 359 7.7E-16 T 09-03-2017 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain L21SP3_RS09045 cd301242e518f61bd3dc3483f99894c4 382 Pfam PF04326 Putative DNA-binding domain 14 127 5.4E-20 T 09-03-2017 IPR007421 Schlafen, AAA domain GO:0005524 L21SP3_RS03095 c0e0d4bcb9236f0118a5373d172cb8e1 313 PIRSF PIRSF036894 2 312 1.2E-81 T 09-03-2017 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 L21SP3_RS03095 c0e0d4bcb9236f0118a5373d172cb8e1 313 Pfam PF01238 Phosphomannose isomerase type I 9 115 2.9E-13 T 09-03-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 L21SP3_RS03095 c0e0d4bcb9236f0118a5373d172cb8e1 313 SUPERFAMILY SSF51182 1 297 1.52E-74 T 09-03-2017 IPR011051 RmlC-like cupin domain L21SP3_RS03095 c0e0d4bcb9236f0118a5373d172cb8e1 313 Gene3D G3DSA:2.60.120.10 1 220 4.3E-68 T 09-03-2017 IPR014710 RmlC-like jelly roll fold L21SP3_RS09125 3bc99cb14052216bf4d4b03344c78f90 571 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 215 446 8.2E-56 T 09-03-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 L21SP3_RS09125 3bc99cb14052216bf4d4b03344c78f90 571 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 19 179 1.6E-27 T 09-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP3_RS09125 3bc99cb14052216bf4d4b03344c78f90 571 Gene3D G3DSA:3.40.50.920 467 570 8.0E-9 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP3_RS09125 3bc99cb14052216bf4d4b03344c78f90 571 SUPERFAMILY SSF52518 203 455 2.99E-64 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS09125 3bc99cb14052216bf4d4b03344c78f90 571 SUPERFAMILY SSF53323 12 224 5.1E-32 T 09-03-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 L21SP3_RS09125 3bc99cb14052216bf4d4b03344c78f90 571 SUPERFAMILY SSF52922 467 570 6.28E-11 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 L21SP3_RS09125 3bc99cb14052216bf4d4b03344c78f90 571 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 11 567 3.7E-188 T 09-03-2017 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 L21SP3_RS09125 3bc99cb14052216bf4d4b03344c78f90 571 Gene3D G3DSA:3.40.50.970 199 388 7.0E-70 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS09125 3bc99cb14052216bf4d4b03344c78f90 571 Gene3D G3DSA:3.40.920.10 11 183 4.3E-28 T 09-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP3_RS02950 41c52d91e050bf3d97151a6bfa124695 158 Gene3D G3DSA:2.40.50.140 98 155 1.5E-10 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS02950 41c52d91e050bf3d97151a6bfa124695 158 SUPERFAMILY SSF141322 97 156 5.36E-9 T 09-03-2017 L21SP3_RS02950 41c52d91e050bf3d97151a6bfa124695 158 Pfam PF01957 NfeD-like C-terminal, partner-binding 13 156 4.1E-19 T 09-03-2017 IPR002810 NfeD-like, C-terminal domain L21SP3_RS06060 dad09eea7bcde5a1644e09685c079865 339 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 3 333 4.1E-72 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS06060 dad09eea7bcde5a1644e09685c079865 339 SUPERFAMILY SSF51445 3 337 9.16E-79 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS06060 dad09eea7bcde5a1644e09685c079865 339 Gene3D G3DSA:3.20.20.300 3 337 2.2E-88 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 L21SP3_RS03970 b5dc08433a274b8f295310049c85e23e 196 Pfam PF02508 Rnf-Nqr subunit, membrane protein 9 195 1.6E-55 T 09-03-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 L21SP3_RS03970 b5dc08433a274b8f295310049c85e23e 196 PIRSF PIRSF006102 4 196 2.0E-53 T 09-03-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 L21SP3_RS03970 b5dc08433a274b8f295310049c85e23e 196 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 7 195 1.1E-69 T 09-03-2017 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 L21SP3_RS05380 08b8e5cff0947fcb7a28fa84df21134c 144 Gene3D G3DSA:1.10.60.10 79 131 1.5E-12 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP3_RS05380 08b8e5cff0947fcb7a28fa84df21134c 144 Gene3D G3DSA:1.10.10.10 5 74 3.7E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS05380 08b8e5cff0947fcb7a28fa84df21134c 144 SUPERFAMILY SSF47979 66 125 4.84E-12 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP3_RS05380 08b8e5cff0947fcb7a28fa84df21134c 144 SUPERFAMILY SSF46785 5 65 3.18E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS05380 08b8e5cff0947fcb7a28fa84df21134c 144 SMART SM00529 27 126 6.9E-28 T 09-03-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 L21SP3_RS05380 08b8e5cff0947fcb7a28fa84df21134c 144 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 62 6.4E-17 T 09-03-2017 IPR022687 DTXR-type HTH domain GO:0003677 L21SP3_RS05380 08b8e5cff0947fcb7a28fa84df21134c 144 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 66 126 9.9E-15 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 L21SP3_RS08480 3cdfc2695ecb28c95b257727f836c296 140 Gene3D G3DSA:2.30.110.10 2 139 8.3E-18 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 L21SP3_RS08480 3cdfc2695ecb28c95b257727f836c296 140 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 93 6.7E-10 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 L21SP3_RS08480 3cdfc2695ecb28c95b257727f836c296 140 SUPERFAMILY SSF50475 2 139 4.49E-19 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 L21SP3_RS04315 b97db1e468540e14e0497305c66177b8 321 Gene3D G3DSA:3.30.470.20 192 305 2.0E-24 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 L21SP3_RS04315 b97db1e468540e14e0497305c66177b8 321 Gene3D G3DSA:3.30.1490.20 122 190 3.7E-10 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 L21SP3_RS04315 b97db1e468540e14e0497305c66177b8 321 Pfam PF02655 ATP-grasp domain 118 275 1.3E-17 T 09-03-2017 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 L21SP3_RS04315 b97db1e468540e14e0497305c66177b8 321 Gene3D G3DSA:3.40.50.20 7 121 3.6E-35 T 09-03-2017 IPR016185 Pre-ATP-grasp domain L21SP3_RS04315 b97db1e468540e14e0497305c66177b8 321 SUPERFAMILY SSF56059 120 292 2.12E-23 T 09-03-2017 L21SP3_RS03530 3260ae25e33a2a0939fc98c25e2f370c 255 Gene3D G3DSA:3.60.10.10 4 254 9.5E-81 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase L21SP3_RS03530 3260ae25e33a2a0939fc98c25e2f370c 255 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 246 8.5E-28 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase L21SP3_RS03530 3260ae25e33a2a0939fc98c25e2f370c 255 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 09-03-2017 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 L21SP3_RS03530 3260ae25e33a2a0939fc98c25e2f370c 255 SUPERFAMILY SSF56219 4 254 4.06E-72 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase L21SP3_RS03530 3260ae25e33a2a0939fc98c25e2f370c 255 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 3 253 8.4E-77 T 09-03-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 L21SP3_RS03530 3260ae25e33a2a0939fc98c25e2f370c 255 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 3 253 8.0E-88 T 09-03-2017 L21SP3_RS10220 f379f4e01c366c67d6c2c4ee3ea30323 172 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 151 171 1.7E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS10220 f379f4e01c366c67d6c2c4ee3ea30323 172 Pfam PF07589 PEP-CTERM motif 150 171 2.2E-6 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS08170 4c9cda6cc98666077a82dc4fefa6c84f 473 SUPERFAMILY SSF54001 319 432 7.01E-21 T 09-03-2017 L21SP3_RS08170 4c9cda6cc98666077a82dc4fefa6c84f 473 Gene3D G3DSA:3.90.260.10 369 429 9.7E-4 T 09-03-2017 IPR002931 Transglutaminase-like L21SP3_RS08170 4c9cda6cc98666077a82dc4fefa6c84f 473 Pfam PF01841 Transglutaminase-like superfamily 333 428 5.8E-17 T 09-03-2017 IPR002931 Transglutaminase-like L21SP3_RS08170 4c9cda6cc98666077a82dc4fefa6c84f 473 SMART SM00460 365 430 5.0E-11 T 09-03-2017 IPR002931 Transglutaminase-like L21SP3_RS00100 a7e6e2c699b72dd25e8f4c2fb87605e3 303 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 20 261 1.0E-31 T 09-03-2017 L21SP3_RS00100 a7e6e2c699b72dd25e8f4c2fb87605e3 303 PIRSF PIRSF005355 2 302 5.3E-53 T 09-03-2017 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 L21SP3_RS00100 a7e6e2c699b72dd25e8f4c2fb87605e3 303 Pfam PF01040 UbiA prenyltransferase family 22 269 2.7E-33 T 09-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 L21SP3_RS02310 9fc9051dfb6eb9909df4849d251f2f21 164 SUPERFAMILY SSF46689 29 140 1.25E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS02310 9fc9051dfb6eb9909df4849d251f2f21 164 Pfam PF13565 Homeodomain-like domain 58 138 1.7E-13 T 09-03-2017 L21SP3_RS08245 9c0194ae558992e6d6910d8d08e0e397 574 Pfam PF03235 Protein of unknown function DUF262 27 255 3.6E-36 T 09-03-2017 IPR004919 Domain of unknown function DUF262 L21SP3_RS08245 9c0194ae558992e6d6910d8d08e0e397 574 Pfam PF07510 Protein of unknown function (DUF1524) 431 566 1.3E-26 T 09-03-2017 IPR011089 Domain of unknown function DUF1524 L21SP3_RS11720 957f6bfc10789663afefc6448e5c0245 549 SUPERFAMILY SSF56300 167 226 9.49E-15 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS11720 957f6bfc10789663afefc6448e5c0245 549 SUPERFAMILY SSF56300 338 441 9.49E-15 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS11720 957f6bfc10789663afefc6448e5c0245 549 SUPERFAMILY SSF56300 253 304 9.49E-15 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS11720 957f6bfc10789663afefc6448e5c0245 549 Gene3D G3DSA:3.60.21.10 165 236 8.4E-6 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS11720 957f6bfc10789663afefc6448e5c0245 549 Gene3D G3DSA:3.60.21.10 438 442 8.4E-6 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS09945 dc2ffbe125111c944ebfce7d41434962 97 SUPERFAMILY SSF55021 10 91 1.9E-17 T 09-03-2017 L21SP3_RS09945 dc2ffbe125111c944ebfce7d41434962 97 Pfam PF13740 ACT domain 9 85 6.3E-13 T 09-03-2017 L21SP3_RS09945 dc2ffbe125111c944ebfce7d41434962 97 Gene3D G3DSA:3.30.70.260 9 97 1.0E-25 T 09-03-2017 L21SP3_RS00945 9f0fcb7f2d6f10bd26fa1ea4955075a8 291 Pfam PF00535 Glycosyl transferase family 2 6 131 5.1E-26 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 L21SP3_RS00945 9f0fcb7f2d6f10bd26fa1ea4955075a8 291 Gene3D G3DSA:3.90.550.10 6 220 2.7E-38 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS00945 9f0fcb7f2d6f10bd26fa1ea4955075a8 291 SUPERFAMILY SSF53448 3 243 9.57E-46 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS05770 2b75d18b568ce0df9682cf9013275bcd 206 Gene3D G3DSA:3.40.1360.10 7 107 3.2E-5 T 09-03-2017 L21SP3_RS05770 2b75d18b568ce0df9682cf9013275bcd 206 SUPERFAMILY SSF160945 14 159 1.57E-9 T 09-03-2017 L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 Pfam PF00271 Helicase conserved C-terminal domain 435 543 2.4E-20 T 09-03-2017 IPR001650 Helicase, C-terminal L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 SUPERFAMILY SSF46600 617 653 3.14E-9 T 09-03-2017 IPR001943 UVR domain GO:0005515 L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 3 651 0.0 T 09-03-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 Pfam PF02151 UvrB/uvrC motif 624 652 1.0E-7 T 09-03-2017 IPR001943 UVR domain GO:0005515 L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 Gene3D G3DSA:4.10.860.10 620 653 2.9E-11 T 09-03-2017 IPR001943 UVR domain GO:0005515 L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 Gene3D G3DSA:3.40.50.300 417 581 1.5E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 SUPERFAMILY SSF52540 457 577 2.49E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 SUPERFAMILY SSF52540 32 81 2.49E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 Gene3D G3DSA:3.30.2060.10 162 228 8.3E-8 T 09-03-2017 L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 SMART SM00490 458 544 8.2E-20 T 09-03-2017 IPR001650 Helicase, C-terminal L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 Gene3D G3DSA:3.40.50.300 386 406 1.8E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 Gene3D G3DSA:3.40.50.300 276 336 1.8E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 Gene3D G3DSA:3.40.50.300 5 88 1.8E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 Hamap MF_00204 UvrABC system protein B [uvrB]. 2 654 43.161 T 09-03-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 SUPERFAMILY SSF52540 1 413 5.12E-131 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 Pfam PF12344 Ultra-violet resistance protein B 550 592 4.9E-23 T 09-03-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 Pfam PF04851 Type III restriction enzyme, res subunit 12 113 1.1E-10 T 09-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 L21SP3_RS05925 8f6cd5bb0495f4c1b966ec1624b09fd7 661 SMART SM00487 8 424 1.4E-27 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain L21SP3_RS03175 3e270488126413ce7cfe2e71985a8027 172 Gene3D G3DSA:1.10.1740.10 8 93 1.8E-17 T 09-03-2017 L21SP3_RS03175 3e270488126413ce7cfe2e71985a8027 172 Pfam PF04542 Sigma-70 region 2 14 80 9.2E-13 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03175 3e270488126413ce7cfe2e71985a8027 172 SUPERFAMILY SSF88946 10 93 3.14E-17 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03175 3e270488126413ce7cfe2e71985a8027 172 Gene3D G3DSA:1.10.10.10 104 166 2.1E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS03175 3e270488126413ce7cfe2e71985a8027 172 SUPERFAMILY SSF88659 103 166 1.85E-9 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS03175 3e270488126413ce7cfe2e71985a8027 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 163 2.7E-21 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS00415 d8459a9a912d1720270e6a084a83f34d 279 Pfam PF08867 FRG domain 26 115 8.6E-24 T 09-03-2017 IPR014966 FRG domain L21SP3_RS00415 d8459a9a912d1720270e6a084a83f34d 279 SMART SM00901 23 122 5.0E-26 T 09-03-2017 IPR014966 FRG domain L21SP3_RS05080 d49c3927c86be4c068977cfbf1d35172 405 SUPERFAMILY SSF56954 1 401 7.46E-88 T 09-03-2017 L21SP3_RS05080 d49c3927c86be4c068977cfbf1d35172 405 Gene3D G3DSA:1.20.1600.10 1 400 7.4E-81 T 09-03-2017 L21SP3_RS05080 d49c3927c86be4c068977cfbf1d35172 405 Pfam PF02321 Outer membrane efflux protein 1 193 3.6E-30 T 09-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP3_RS05080 d49c3927c86be4c068977cfbf1d35172 405 Pfam PF02321 Outer membrane efflux protein 221 399 1.5E-34 T 09-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP3_RS05080 d49c3927c86be4c068977cfbf1d35172 405 PIRSF PIRSF001892 1 405 9.0E-84 T 09-03-2017 IPR028351 Cyclolysin transport protein CyaE GO:0005215 L21SP3_RS09315 b0c8225b15c84d0ecdb2377a736e43a9 802 SUPERFAMILY SSF51905 354 407 1.75E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09315 b0c8225b15c84d0ecdb2377a736e43a9 802 SUPERFAMILY SSF51905 275 294 1.75E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09315 b0c8225b15c84d0ecdb2377a736e43a9 802 SUPERFAMILY SSF51905 15 177 1.75E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09315 b0c8225b15c84d0ecdb2377a736e43a9 802 Pfam PF12831 FAD dependent oxidoreductase 21 434 8.5E-98 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09315 b0c8225b15c84d0ecdb2377a736e43a9 802 Gene3D G3DSA:3.50.50.60 358 438 3.6E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09315 b0c8225b15c84d0ecdb2377a736e43a9 802 Gene3D G3DSA:3.50.50.60 15 164 3.6E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09315 b0c8225b15c84d0ecdb2377a736e43a9 802 Gene3D G3DSA:3.50.50.60 201 223 3.6E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS04110 3c4264a1328adc9ad323b412ec13d92a 226 SUPERFAMILY SSF56112 47 196 1.9E-12 T 09-03-2017 IPR011009 Protein kinase-like domain L21SP3_RS04110 3c4264a1328adc9ad323b412ec13d92a 226 Pfam PF01636 Phosphotransferase enzyme family 64 125 3.6E-10 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase L21SP3_RS04110 3c4264a1328adc9ad323b412ec13d92a 226 Gene3D G3DSA:3.90.1200.10 60 187 9.9E-10 T 09-03-2017 L21SP3_RS07615 aa5d76b3feb7c27a80880e7448d6ade7 209 Pfam PF01618 MotA/TolQ/ExbB proton channel family 81 187 5.0E-23 T 09-03-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 L21SP3_RS09135 904905c922981964287b1e34193b6188 385 Pfam PF07885 Ion channel 301 383 1.1E-15 T 09-03-2017 IPR013099 Potassium channel domain L21SP3_RS09135 904905c922981964287b1e34193b6188 385 Gene3D G3DSA:1.10.287.70 292 383 3.8E-18 T 09-03-2017 L21SP3_RS09135 904905c922981964287b1e34193b6188 385 SUPERFAMILY SSF81324 295 384 1.02E-16 T 09-03-2017 L21SP3_RS09940 5ba2afd490fdde149f928fcc4c7713cc 106 SUPERFAMILY SSF51182 10 105 4.22E-14 T 09-03-2017 IPR011051 RmlC-like cupin domain L21SP3_RS09940 5ba2afd490fdde149f928fcc4c7713cc 106 Gene3D G3DSA:2.60.120.10 18 106 6.1E-33 T 09-03-2017 IPR014710 RmlC-like jelly roll fold L21SP3_RS09940 5ba2afd490fdde149f928fcc4c7713cc 106 Pfam PF07883 Cupin domain 50 104 9.2E-11 T 09-03-2017 IPR013096 Cupin 2, conserved barrel L21SP3_RS03795 3da8cc7b4272d2d1aefc6ef7c458c3a3 357 SUPERFAMILY SSF75005 30 348 2.36E-62 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS03795 3da8cc7b4272d2d1aefc6ef7c458c3a3 357 Pfam PF04616 Glycosyl hydrolases family 43 31 337 1.3E-57 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS03795 3da8cc7b4272d2d1aefc6ef7c458c3a3 357 PIRSF PIRSF025414 2 355 1.0E-120 T 09-03-2017 IPR016828 Alpha-L-arabinofuranosidase KEGG: 00520+3.2.1.55 L21SP3_RS03795 3da8cc7b4272d2d1aefc6ef7c458c3a3 357 Gene3D G3DSA:2.115.10.20 27 354 6.6E-89 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS08335 83eb36abaa033fa6471d5a454b46aa6d 256 ProSitePatterns PS00018 EF-hand calcium-binding domain. 233 245 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS08335 83eb36abaa033fa6471d5a454b46aa6d 256 Gene3D G3DSA:1.10.1330.10 194 253 6.5E-9 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS08335 83eb36abaa033fa6471d5a454b46aa6d 256 SUPERFAMILY SSF63446 194 253 9.29E-9 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS00590 bdf68bf1a65e8f8953dfcd1e40f2807d 1111 SMART SM00507 696 751 0.0018 T 09-03-2017 IPR003615 HNH nuclease L21SP3_RS00590 bdf68bf1a65e8f8953dfcd1e40f2807d 1111 TIGRFAM TIGR01865 cas_Csn1: CRISPR subtype II RNA-guided endonuclease Cas9 6 887 2.8E-118 T 09-03-2017 IPR028629 CRISPR-associated endonuclease Cas9 GO:0004519 L21SP3_RS00590 bdf68bf1a65e8f8953dfcd1e40f2807d 1111 Pfam PF13395 HNH endonuclease 709 759 1.3E-19 T 09-03-2017 IPR003615 HNH nuclease L21SP3_RS02500 3178033d62eba62f2624ff2f06aad733 235 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 235 107.614 T 09-03-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 L21SP3_RS02500 3178033d62eba62f2624ff2f06aad733 235 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 4 234 1.2E-91 T 09-03-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 L21SP3_RS02500 3178033d62eba62f2624ff2f06aad733 235 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 4 235 1.9E-83 T 09-03-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 L21SP3_RS02500 3178033d62eba62f2624ff2f06aad733 235 SUPERFAMILY SSF63892 1 235 5.75E-86 T 09-03-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 L21SP3_RS02500 3178033d62eba62f2624ff2f06aad733 235 Gene3D G3DSA:3.20.20.70 2 235 4.9E-94 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS06785 d43f9bd6d841b3d63b8356b476cfaafe 163 SUPERFAMILY SSF89447 3 145 4.71E-26 T 09-03-2017 L21SP3_RS06785 d43f9bd6d841b3d63b8356b476cfaafe 163 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 163 26.641 T 09-03-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 L21SP3_RS06785 d43f9bd6d841b3d63b8356b476cfaafe 163 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 79 145 3.0E-11 T 09-03-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 L21SP3_RS06785 d43f9bd6d841b3d63b8356b476cfaafe 163 Pfam PF02381 MraZ protein, putative antitoxin-like 85 139 5.1E-18 T 09-03-2017 IPR020603 MraZ domain L21SP3_RS06305 4de31fdcd42d3e89c444e5e55e0d3ed8 417 PRINTS PR00812 Bacterial general secretion pathway protein F signature 72 84 1.1E-17 T 09-03-2017 IPR003004 GspF/PilC family L21SP3_RS06305 4de31fdcd42d3e89c444e5e55e0d3ed8 417 PRINTS PR00812 Bacterial general secretion pathway protein F signature 172 200 1.1E-17 T 09-03-2017 IPR003004 GspF/PilC family L21SP3_RS06305 4de31fdcd42d3e89c444e5e55e0d3ed8 417 PRINTS PR00812 Bacterial general secretion pathway protein F signature 396 415 1.1E-17 T 09-03-2017 IPR003004 GspF/PilC family L21SP3_RS06305 4de31fdcd42d3e89c444e5e55e0d3ed8 417 PRINTS PR00812 Bacterial general secretion pathway protein F signature 380 394 1.1E-17 T 09-03-2017 IPR003004 GspF/PilC family L21SP3_RS06305 4de31fdcd42d3e89c444e5e55e0d3ed8 417 Pfam PF00482 Type II secretion system (T2SS), protein F 285 407 6.8E-25 T 09-03-2017 IPR018076 Type II secretion system F domain L21SP3_RS06305 4de31fdcd42d3e89c444e5e55e0d3ed8 417 Pfam PF00482 Type II secretion system (T2SS), protein F 76 200 4.8E-29 T 09-03-2017 IPR018076 Type II secretion system F domain L21SP3_RS06305 4de31fdcd42d3e89c444e5e55e0d3ed8 417 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 172 200 - T 09-03-2017 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 L21SP3_RS03830 665b7307a39dd28cd6bba8ddf6b72d17 407 Pfam PF01609 Transposase DDE domain 131 346 1.2E-20 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS03830 665b7307a39dd28cd6bba8ddf6b72d17 407 SUPERFAMILY SSF53098 128 375 3.19E-25 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS03830 665b7307a39dd28cd6bba8ddf6b72d17 407 Gene3D G3DSA:3.90.350.10 255 322 2.3E-4 T 09-03-2017 IPR014736 Transposase, Tn5-like, core L21SP3_RS03830 665b7307a39dd28cd6bba8ddf6b72d17 407 Pfam PF14294 Domain of unknown function (DUF4372) 7 73 1.4E-14 T 09-03-2017 IPR025399 Domain of unknown function DUF4372 L21SP3_RS08255 39f89a68e40bdc650e7019d795d50a55 237 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 236 1.4E-46 T 09-03-2017 IPR011078 Uncharacterised protein family UPF0001 L21SP3_RS08255 39f89a68e40bdc650e7019d795d50a55 237 Pfam PF01168 Alanine racemase, N-terminal domain 11 236 1.3E-16 T 09-03-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 L21SP3_RS08255 39f89a68e40bdc650e7019d795d50a55 237 SUPERFAMILY SSF51419 1 236 1.14E-59 T 09-03-2017 IPR029066 PLP-binding barrel L21SP3_RS08255 39f89a68e40bdc650e7019d795d50a55 237 Gene3D G3DSA:3.20.20.10 1 236 3.3E-69 T 09-03-2017 IPR029066 PLP-binding barrel L21SP3_RS08255 39f89a68e40bdc650e7019d795d50a55 237 PIRSF PIRSF004848 1 237 1.0E-59 T 09-03-2017 IPR011078 Uncharacterised protein family UPF0001 L21SP3_RS10705 0b4556c104d7fe0156f8843dcba72f46 947 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 730 882 5.3E-25 T 09-03-2017 L21SP3_RS10705 0b4556c104d7fe0156f8843dcba72f46 947 Gene3D G3DSA:2.60.120.200 686 887 1.4E-28 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10705 0b4556c104d7fe0156f8843dcba72f46 947 Gene3D G3DSA:1.10.1330.10 892 941 4.6E-5 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS10705 0b4556c104d7fe0156f8843dcba72f46 947 SMART SM00560 745 879 0.008 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS10705 0b4556c104d7fe0156f8843dcba72f46 947 Pfam PF14323 GxGYxYP putative glycoside hydrolase C-terminal domain 444 678 3.6E-54 T 09-03-2017 IPR025832 GxGYxYP putative glycoside hydrolase, C-terminal L21SP3_RS10705 0b4556c104d7fe0156f8843dcba72f46 947 SUPERFAMILY SSF49899 674 888 1.14E-30 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10705 0b4556c104d7fe0156f8843dcba72f46 947 SUPERFAMILY SSF63446 892 942 1.11E-5 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS10705 0b4556c104d7fe0156f8843dcba72f46 947 Pfam PF16216 GxGYxY sequence motif in domain of unknown function N-terminal 207 417 8.3E-39 T 09-03-2017 IPR032626 GxGYxYP putative glycoside hydrolase, N-terminal L21SP3_RS00960 c2cc2a6cd4fe1229679c2cabb4b33c75 736 Gene3D G3DSA:2.60.120.200 380 535 7.9E-7 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00960 c2cc2a6cd4fe1229679c2cabb4b33c75 736 SUPERFAMILY SSF49899 378 537 5.7E-6 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS00960 c2cc2a6cd4fe1229679c2cabb4b33c75 736 SUPERFAMILY SSF50939 18 94 6.87E-8 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS00960 c2cc2a6cd4fe1229679c2cabb4b33c75 736 SUPERFAMILY SSF50939 152 345 6.87E-8 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS00960 c2cc2a6cd4fe1229679c2cabb4b33c75 736 Gene3D G3DSA:2.120.10.10 50 127 4.4E-8 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS00960 c2cc2a6cd4fe1229679c2cabb4b33c75 736 Gene3D G3DSA:2.120.10.10 173 251 4.4E-8 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS03540 b800be1e637f24ad696509d2cceff25d 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 5.5E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 L21SP3_RS03540 b800be1e637f24ad696509d2cceff25d 220 SUPERFAMILY SSF46689 11 84 6.98E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS03540 b800be1e637f24ad696509d2cceff25d 220 Gene3D G3DSA:1.10.357.10 11 216 5.1E-20 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 L21SP3_RS03540 b800be1e637f24ad696509d2cceff25d 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.5E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 L21SP3_RS03540 b800be1e637f24ad696509d2cceff25d 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.5E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 L21SP3_RS11165 a1848344044bf3070c88d5b18605786f 407 Gene3D G3DSA:3.90.350.10 266 322 4.0E-4 T 09-03-2017 IPR014736 Transposase, Tn5-like, core L21SP3_RS11165 a1848344044bf3070c88d5b18605786f 407 Pfam PF14294 Domain of unknown function (DUF4372) 7 73 3.2E-14 T 09-03-2017 IPR025399 Domain of unknown function DUF4372 L21SP3_RS11165 a1848344044bf3070c88d5b18605786f 407 SUPERFAMILY SSF53098 128 381 2.05E-26 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS11165 a1848344044bf3070c88d5b18605786f 407 Pfam PF01609 Transposase DDE domain 131 346 1.2E-22 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS10980 9e127f60b05da095b1d96c5ae8c671b9 278 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 127 245 4.6E-38 T 09-03-2017 IPR003390 DNA integrity scanning protein, DisA, N-terminal L21SP3_RS10980 9e127f60b05da095b1d96c5ae8c671b9 278 SUPERFAMILY SSF143597 56 248 8.37E-50 T 09-03-2017 L21SP3_RS10980 9e127f60b05da095b1d96c5ae8c671b9 278 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 21 257 5.8E-58 T 09-03-2017 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 L21SP3_RS10980 9e127f60b05da095b1d96c5ae8c671b9 278 Gene3D G3DSA:3.40.1700.10 120 249 1.3E-42 T 09-03-2017 L21SP3_RS10980 9e127f60b05da095b1d96c5ae8c671b9 278 PIRSF PIRSF004793 16 271 5.9E-66 T 09-03-2017 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 L21SP3_RS08400 21ac9cba6b2d974e04cc03916e2ee60e 78 Pfam PF10636 Hemin uptake protein hemP 42 78 4.3E-16 T 09-03-2017 IPR019600 Hemin uptake protein HemP L21SP3_RS08400 21ac9cba6b2d974e04cc03916e2ee60e 78 Gene3D G3DSA:2.10.70.10 39 78 4.8E-17 T 09-03-2017 L21SP3_RS05850 6e9fea6f48b6a0032c77bebd33e84b86 266 Pfam PF02811 PHP domain 13 96 9.4E-9 T 09-03-2017 IPR004013 PHP domain GO:0003824 L21SP3_RS05850 6e9fea6f48b6a0032c77bebd33e84b86 266 Gene3D G3DSA:3.20.20.140 10 254 1.4E-36 T 09-03-2017 L21SP3_RS05850 6e9fea6f48b6a0032c77bebd33e84b86 266 SUPERFAMILY SSF89550 11 257 7.46E-37 T 09-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 L21SP3_RS06400 b4d08734972989b2e4ff92fe4b95b676 348 Gene3D G3DSA:1.10.510.10 86 277 3.8E-55 T 09-03-2017 L21SP3_RS06400 b4d08734972989b2e4ff92fe4b95b676 348 SMART SM00220 19 281 2.6E-66 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 L21SP3_RS06400 b4d08734972989b2e4ff92fe4b95b676 348 Pfam PF00069 Protein kinase domain 19 269 3.7E-57 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 L21SP3_RS06400 b4d08734972989b2e4ff92fe4b95b676 348 SUPERFAMILY SSF56112 17 280 1.12E-76 T 09-03-2017 IPR011009 Protein kinase-like domain L21SP3_RS06400 b4d08734972989b2e4ff92fe4b95b676 348 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 25 57 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 L21SP3_RS06400 b4d08734972989b2e4ff92fe4b95b676 348 Gene3D G3DSA:3.30.200.20 18 85 6.5E-22 T 09-03-2017 L21SP3_RS06400 b4d08734972989b2e4ff92fe4b95b676 348 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 L21SP3_RS04335 bfde87b45c06858663ac0ce7bb8808ab 158 SUPERFAMILY SSF46785 19 124 3.52E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS04335 bfde87b45c06858663ac0ce7bb8808ab 158 Pfam PF01475 Ferric uptake regulator family 26 128 2.1E-12 T 09-03-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 L21SP3_RS04335 bfde87b45c06858663ac0ce7bb8808ab 158 Gene3D G3DSA:1.10.10.10 20 94 7.4E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS03500 e1e8296c51d5c51666214c9b1010b69b 93 Gene3D G3DSA:3.40.30.10 3 84 1.6E-21 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS03500 e1e8296c51d5c51666214c9b1010b69b 93 SMART SM01248 11 92 1.0E-11 T 09-03-2017 IPR011649 KaiB domain GO:0048511 L21SP3_RS03500 e1e8296c51d5c51666214c9b1010b69b 93 SUPERFAMILY SSF52833 3 85 2.8E-15 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS03500 e1e8296c51d5c51666214c9b1010b69b 93 Pfam PF07689 KaiB domain 11 85 2.5E-15 T 09-03-2017 IPR011649 KaiB domain GO:0048511 L21SP3_RS07350 f9d0a826309312f2540e46e72650896a 127 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS07350 f9d0a826309312f2540e46e72650896a 127 SUPERFAMILY SSF54523 10 84 6.51E-14 T 09-03-2017 L21SP3_RS07350 f9d0a826309312f2540e46e72650896a 127 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 29 5.3E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS07350 f9d0a826309312f2540e46e72650896a 127 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 8 29 1.3E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS06505 9cab04663a68fe26a1f3db3b5a587fe0 85 Gene3D G3DSA:3.40.30.10 3 50 2.6E-6 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS06505 9cab04663a68fe26a1f3db3b5a587fe0 85 SUPERFAMILY SSF52833 3 84 2.74E-9 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS06505 9cab04663a68fe26a1f3db3b5a587fe0 85 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 3 81 7.1E-8 T 09-03-2017 L21SP3_RS09275 db291f7154c6a0fa0dfc51bbc6943e2f 226 Gene3D G3DSA:3.40.50.450 16 219 9.4E-64 T 09-03-2017 L21SP3_RS09275 db291f7154c6a0fa0dfc51bbc6943e2f 226 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 37 208 5.8E-41 T 09-03-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG L21SP3_RS09275 db291f7154c6a0fa0dfc51bbc6943e2f 226 Pfam PF03641 Possible lysine decarboxylase 79 209 1.2E-32 T 09-03-2017 IPR031100 LOG family L21SP3_RS09275 db291f7154c6a0fa0dfc51bbc6943e2f 226 SUPERFAMILY SSF102405 9 210 1.98E-60 T 09-03-2017 L21SP3_RS06810 9d7e8241a7376a4fc4142d1888638c36 390 SUPERFAMILY SSF144091 12 211 3.66E-33 T 09-03-2017 L21SP3_RS06810 9d7e8241a7376a4fc4142d1888638c36 390 Pfam PF01694 Rhomboid family 62 207 8.4E-27 T 09-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 L21SP3_RS06810 9d7e8241a7376a4fc4142d1888638c36 390 Gene3D G3DSA:1.20.1540.10 14 207 1.7E-30 T 09-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 L21SP3_RS03975 89fb884323de878b6c5c9adb55c33f26 284 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 20 212 1.6E-28 T 09-03-2017 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 L21SP3_RS03975 89fb884323de878b6c5c9adb55c33f26 284 Gene3D G3DSA:3.30.70.20 239 278 8.5E-7 T 09-03-2017 L21SP3_RS03975 89fb884323de878b6c5c9adb55c33f26 284 SUPERFAMILY SSF54862 152 280 4.83E-14 T 09-03-2017 L21SP3_RS03975 89fb884323de878b6c5c9adb55c33f26 284 Pfam PF00037 4Fe-4S binding domain 180 201 1.7E-6 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain L21SP3_RS03975 89fb884323de878b6c5c9adb55c33f26 284 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 232 277 2.5E-6 T 09-03-2017 L21SP3_RS03975 89fb884323de878b6c5c9adb55c33f26 284 Gene3D G3DSA:3.30.70.20 156 190 3.7E-11 T 09-03-2017 L21SP3_RS03975 89fb884323de878b6c5c9adb55c33f26 284 Gene3D G3DSA:3.30.70.20 191 238 5.8E-11 T 09-03-2017 L21SP3_RS03975 89fb884323de878b6c5c9adb55c33f26 284 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 186 197 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site L21SP3_RS03975 89fb884323de878b6c5c9adb55c33f26 284 Pfam PF04060 Putative Fe-S cluster 60 92 8.0E-11 T 09-03-2017 IPR007202 4Fe-4S domain GO:0051536 L21SP3_RS06390 2ef71e670db9845c484dee5aeec893ce 543 Gene3D G3DSA:3.40.50.300 258 539 6.0E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06390 2ef71e670db9845c484dee5aeec893ce 543 Gene3D G3DSA:3.30.450.90 155 252 1.0E-14 T 09-03-2017 L21SP3_RS06390 2ef71e670db9845c484dee5aeec893ce 543 SUPERFAMILY SSF52540 158 537 1.17E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06390 2ef71e670db9845c484dee5aeec893ce 543 Pfam PF00437 Type II/IV secretion system protein 170 374 1.5E-15 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS10165 047a6e7d1a623f0622cdc6fb041dfa18 250 Gene3D G3DSA:3.30.1270.10 213 248 1.3E-38 T 09-03-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 L21SP3_RS10165 047a6e7d1a623f0622cdc6fb041dfa18 250 Gene3D G3DSA:3.30.1270.10 82 136 1.3E-38 T 09-03-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 L21SP3_RS10165 047a6e7d1a623f0622cdc6fb041dfa18 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 2.7E-94 T 09-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 L21SP3_RS10165 047a6e7d1a623f0622cdc6fb041dfa18 250 SUPERFAMILY SSF75625 5 246 6.28E-90 T 09-03-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 L21SP3_RS10165 047a6e7d1a623f0622cdc6fb041dfa18 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.572 T 09-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 L21SP3_RS10165 047a6e7d1a623f0622cdc6fb041dfa18 250 Pfam PF01709 Transcriptional regulator 5 238 3.6E-89 T 09-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 L21SP3_RS10165 047a6e7d1a623f0622cdc6fb041dfa18 250 Gene3D G3DSA:3.30.70.980 137 205 1.8E-22 T 09-03-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 L21SP3_RS10165 047a6e7d1a623f0622cdc6fb041dfa18 250 Gene3D G3DSA:1.10.10.200 1 76 4.3E-33 T 09-03-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like L21SP3_RS05575 de05114844fbc3939ad4ea4b92681eb2 155 Pfam PF01668 SmpB protein 13 74 1.3E-24 T 09-03-2017 IPR000037 SsrA-binding protein GO:0003723 L21SP3_RS05575 de05114844fbc3939ad4ea4b92681eb2 155 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 14 136 3.0E-34 T 09-03-2017 IPR000037 SsrA-binding protein GO:0003723 L21SP3_RS05575 de05114844fbc3939ad4ea4b92681eb2 155 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 62.792 T 09-03-2017 IPR000037 SsrA-binding protein GO:0003723 L21SP3_RS05575 de05114844fbc3939ad4ea4b92681eb2 155 SUPERFAMILY SSF74982 6 136 4.05E-46 T 09-03-2017 IPR023620 Small protein B L21SP3_RS05575 de05114844fbc3939ad4ea4b92681eb2 155 TIGRFAM TIGR00086 smpB: SsrA-binding protein 13 152 2.9E-56 T 09-03-2017 IPR000037 SsrA-binding protein GO:0003723 L21SP3_RS05575 de05114844fbc3939ad4ea4b92681eb2 155 Gene3D G3DSA:2.40.280.10 13 131 1.0E-47 T 09-03-2017 IPR023620 Small protein B L21SP3_RS05575 de05114844fbc3939ad4ea4b92681eb2 155 ProSitePatterns PS01317 SsrA-binding protein. 30 42 - T 09-03-2017 IPR020081 SsrA-binding protein, conserved site L21SP3_RS02485 7b3cf575f43598b81d965d5722cd852f 296 Pfam PF16916 Dimerisation domain of Zinc Transporter 214 287 1.1E-22 T 09-03-2017 IPR027470 Cation efflux protein, cytoplasmic domain L21SP3_RS02485 7b3cf575f43598b81d965d5722cd852f 296 SUPERFAMILY SSF160240 211 287 8.37E-19 T 09-03-2017 L21SP3_RS02485 7b3cf575f43598b81d965d5722cd852f 296 Gene3D G3DSA:3.30.70.1350 212 287 1.2E-22 T 09-03-2017 IPR027470 Cation efflux protein, cytoplasmic domain L21SP3_RS02485 7b3cf575f43598b81d965d5722cd852f 296 Pfam PF01545 Cation efflux family 17 198 9.0E-37 T 09-03-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 L21SP3_RS02485 7b3cf575f43598b81d965d5722cd852f 296 Gene3D G3DSA:1.20.1510.10 12 200 5.2E-39 T 09-03-2017 IPR027469 Cation efflux protein transmembrane domain L21SP3_RS02485 7b3cf575f43598b81d965d5722cd852f 296 SUPERFAMILY SSF161111 10 203 1.96E-42 T 09-03-2017 L21SP3_RS02485 7b3cf575f43598b81d965d5722cd852f 296 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 288 1.1E-57 T 09-03-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 L21SP3_RS00305 e1f74bfa8c1b68847ca3c315f585717c 382 Pfam PF01478 Type IV leader peptidase family 120 165 1.5E-4 T 09-03-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 L21SP3_RS00305 e1f74bfa8c1b68847ca3c315f585717c 382 Pfam PF01478 Type IV leader peptidase family 243 338 1.4E-7 T 09-03-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 L21SP3_RS00305 e1f74bfa8c1b68847ca3c315f585717c 382 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 6 87 2.1E-27 T 09-03-2017 IPR010627 Peptidase A24A, N-terminal L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 SUPERFAMILY SSF50249 30 124 7.86E-13 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 SUPERFAMILY SSF50249 111 196 4.22E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 SUPERFAMILY SSF50249 212 299 1.37E-24 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 SUPERFAMILY SSF50249 451 555 1.42E-26 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 Gene3D G3DSA:2.40.50.140 293 374 1.2E-29 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 Gene3D G3DSA:2.40.50.140 466 545 4.4E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 SMART SM00316 297 369 8.9E-27 T 09-03-2017 IPR022967 RNA-binding domain, S1 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 SMART SM00316 384 456 1.1E-21 T 09-03-2017 IPR022967 RNA-binding domain, S1 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 SMART SM00316 45 110 4.9E-6 T 09-03-2017 IPR022967 RNA-binding domain, S1 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 SMART SM00316 472 543 1.1E-26 T 09-03-2017 IPR022967 RNA-binding domain, S1 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 SMART SM00316 126 193 5.6E-10 T 09-03-2017 IPR022967 RNA-binding domain, S1 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 SMART SM00316 212 282 2.7E-26 T 09-03-2017 IPR022967 RNA-binding domain, S1 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 Pfam PF00575 S1 RNA binding domain 384 456 2.7E-18 T 09-03-2017 IPR003029 S1 domain GO:0003676 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 Pfam PF00575 S1 RNA binding domain 474 543 1.3E-22 T 09-03-2017 IPR003029 S1 domain GO:0003676 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 Pfam PF00575 S1 RNA binding domain 212 282 1.2E-18 T 09-03-2017 IPR003029 S1 domain GO:0003676 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 Pfam PF00575 S1 RNA binding domain 126 193 2.2E-9 T 09-03-2017 IPR003029 S1 domain GO:0003676 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 Pfam PF00575 S1 RNA binding domain 297 369 1.8E-21 T 09-03-2017 IPR003029 S1 domain GO:0003676 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 SUPERFAMILY SSF50249 277 376 1.79E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 Gene3D G3DSA:2.40.50.140 215 292 8.1E-28 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 Gene3D G3DSA:2.40.50.140 381 465 1.3E-25 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 Gene3D G3DSA:2.40.50.140 41 118 9.4E-7 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 Gene3D G3DSA:2.40.50.140 119 194 2.7E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 PRINTS PR00681 Ribosomal protein S1 signature 65 79 1.8E-59 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 PRINTS PR00681 Ribosomal protein S1 signature 234 255 1.8E-59 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 PRINTS PR00681 Ribosomal protein S1 signature 312 331 1.8E-59 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 PRINTS PR00681 Ribosomal protein S1 signature 352 370 1.8E-59 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 PRINTS PR00681 Ribosomal protein S1 signature 148 165 1.8E-59 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 PRINTS PR00681 Ribosomal protein S1 signature 131 147 1.8E-59 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 PRINTS PR00681 Ribosomal protein S1 signature 177 197 1.8E-59 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 PRINTS PR00681 Ribosomal protein S1 signature 107 126 1.8E-59 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 PRINTS PR00681 Ribosomal protein S1 signature 47 65 1.8E-59 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 L21SP3_RS04030 751834d571f4e92624a1a0812a860a34 608 SUPERFAMILY SSF50249 369 461 9.29E-21 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold L21SP3_RS09685 191d785a8dc4a8d6adf113aaea1c1a3d 166 Pfam PF07589 PEP-CTERM motif 142 162 2.1E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS09685 191d785a8dc4a8d6adf113aaea1c1a3d 166 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 143 163 1.8E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS06730 811fe3dd6d9d0ba90b292a37ec284d38 897 SUPERFAMILY SSF82866 235 394 6.67E-33 T 09-03-2017 L21SP3_RS06730 811fe3dd6d9d0ba90b292a37ec284d38 897 Gene3D G3DSA:1.20.1640.10 203 394 4.1E-34 T 09-03-2017 L21SP3_RS06730 811fe3dd6d9d0ba90b292a37ec284d38 897 Gene3D G3DSA:1.20.1640.10 684 892 4.0E-28 T 09-03-2017 L21SP3_RS06730 811fe3dd6d9d0ba90b292a37ec284d38 897 PRINTS PR00702 Acriflavin resistance protein family signature 236 259 3.9E-5 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS06730 811fe3dd6d9d0ba90b292a37ec284d38 897 PRINTS PR00702 Acriflavin resistance protein family signature 263 284 3.9E-5 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS06730 811fe3dd6d9d0ba90b292a37ec284d38 897 PRINTS PR00702 Acriflavin resistance protein family signature 366 389 3.9E-5 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 L21SP3_RS06730 811fe3dd6d9d0ba90b292a37ec284d38 897 SUPERFAMILY SSF82866 670 889 3.66E-30 T 09-03-2017 L21SP3_RS06730 811fe3dd6d9d0ba90b292a37ec284d38 897 Pfam PF03176 MMPL family 171 391 3.8E-20 T 09-03-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 L21SP3_RS06730 811fe3dd6d9d0ba90b292a37ec284d38 897 Pfam PF03176 MMPL family 619 893 1.3E-13 T 09-03-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 L21SP3_RS10100 0c48400bdc46d6d7599c6146ee379dcc 513 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 9 489 4.1E-186 T 09-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 L21SP3_RS10100 0c48400bdc46d6d7599c6146ee379dcc 513 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 47 490 2.6E-159 T 09-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 L21SP3_RS01330 a21a3953cf018718f31637e4a7f95261 268 Gene3D G3DSA:1.10.10.10 34 76 6.0E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS01970 4de67bf660e1781ca1d32b7e95b9a6e5 174 SUPERFAMILY SSF88946 8 86 6.02E-17 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS01970 4de67bf660e1781ca1d32b7e95b9a6e5 174 Gene3D G3DSA:1.10.10.10 110 168 1.1E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS01970 4de67bf660e1781ca1d32b7e95b9a6e5 174 SUPERFAMILY SSF88659 116 168 4.67E-10 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS01970 4de67bf660e1781ca1d32b7e95b9a6e5 174 Gene3D G3DSA:1.10.1740.10 7 86 1.7E-17 T 09-03-2017 L21SP3_RS01970 4de67bf660e1781ca1d32b7e95b9a6e5 174 TIGRFAM TIGR02989 Sig-70_gvs1: RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family 9 165 8.7E-42 T 09-03-2017 IPR014331 RNA polymerase sigma-70 ECF-like, Rhodopirellula baltica L21SP3_RS01970 4de67bf660e1781ca1d32b7e95b9a6e5 174 Pfam PF08281 Sigma-70, region 4 112 158 2.1E-8 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS01970 4de67bf660e1781ca1d32b7e95b9a6e5 174 Pfam PF04542 Sigma-70 region 2 14 80 1.3E-10 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS01970 4de67bf660e1781ca1d32b7e95b9a6e5 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 163 4.0E-19 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS10275 a25fe1d64939ad5487f69bde84e22ba3 709 Pfam PF00209 Sodium:neurotransmitter symporter family 8 234 8.3E-53 T 09-03-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP3_RS10275 a25fe1d64939ad5487f69bde84e22ba3 709 Pfam PF00209 Sodium:neurotransmitter symporter family 246 493 2.1E-49 T 09-03-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP3_RS10275 a25fe1d64939ad5487f69bde84e22ba3 709 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 191 208 3.4E-35 T 09-03-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP3_RS10275 a25fe1d64939ad5487f69bde84e22ba3 709 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 89 115 3.4E-35 T 09-03-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP3_RS10275 a25fe1d64939ad5487f69bde84e22ba3 709 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 431 451 3.4E-35 T 09-03-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP3_RS10275 a25fe1d64939ad5487f69bde84e22ba3 709 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 16 37 3.4E-35 T 09-03-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP3_RS10275 a25fe1d64939ad5487f69bde84e22ba3 709 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 45 64 3.4E-35 T 09-03-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP3_RS10275 a25fe1d64939ad5487f69bde84e22ba3 709 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 353 372 3.4E-35 T 09-03-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 L21SP3_RS10275 a25fe1d64939ad5487f69bde84e22ba3 709 SUPERFAMILY SSF161070 8 493 5.23E-123 T 09-03-2017 L21SP3_RS03745 ea345b43706b24e5f3f27983cef28553 397 Pfam PF00534 Glycosyl transferases group 1 204 367 1.2E-21 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS03745 ea345b43706b24e5f3f27983cef28553 397 SUPERFAMILY SSF53756 7 395 1.33E-60 T 09-03-2017 L21SP3_RS03745 ea345b43706b24e5f3f27983cef28553 397 Gene3D G3DSA:3.40.50.2000 204 369 2.6E-21 T 09-03-2017 L21SP3_RS03745 ea345b43706b24e5f3f27983cef28553 397 Pfam PF13439 Glycosyltransferase Family 4 19 180 7.0E-9 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 L21SP3_RS05265 29ad984e4a6205b30f2b51f2c90ce6e2 506 Pfam PF13229 Right handed beta helix region 187 316 1.3E-9 T 09-03-2017 L21SP3_RS05265 29ad984e4a6205b30f2b51f2c90ce6e2 506 SUPERFAMILY SSF51126 6 379 2.84E-39 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS05265 29ad984e4a6205b30f2b51f2c90ce6e2 506 SMART SM00710 216 238 160.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS05265 29ad984e4a6205b30f2b51f2c90ce6e2 506 SMART SM00710 239 269 570.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS05265 29ad984e4a6205b30f2b51f2c90ce6e2 506 SMART SM00710 298 319 3200.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS05265 29ad984e4a6205b30f2b51f2c90ce6e2 506 SMART SM00710 184 206 1800.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS05265 29ad984e4a6205b30f2b51f2c90ce6e2 506 SMART SM00710 109 137 9900.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS05265 29ad984e4a6205b30f2b51f2c90ce6e2 506 SMART SM00710 365 387 7200.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat L21SP3_RS01765 b6dbeaa2600791eb9f5b72966789ee23 407 Pfam PF14294 Domain of unknown function (DUF4372) 7 73 1.4E-14 T 09-03-2017 IPR025399 Domain of unknown function DUF4372 L21SP3_RS01765 b6dbeaa2600791eb9f5b72966789ee23 407 Pfam PF01609 Transposase DDE domain 131 346 9.8E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS01765 b6dbeaa2600791eb9f5b72966789ee23 407 SUPERFAMILY SSF53098 128 375 2.2E-25 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS01765 b6dbeaa2600791eb9f5b72966789ee23 407 Gene3D G3DSA:3.90.350.10 255 322 2.9E-4 T 09-03-2017 IPR014736 Transposase, Tn5-like, core L21SP3_RS02465 26eadaa2cd14287b11e2a8eb10c3304c 436 PIRSF PIRSF033563 1 436 3.5E-98 T 09-03-2017 IPR008323 Uncharacterised conserved protein UCP033563 L21SP3_RS02465 26eadaa2cd14287b11e2a8eb10c3304c 436 Pfam PF06245 Protein of unknown function (DUF1015) 3 434 2.6E-118 T 09-03-2017 IPR008323 Uncharacterised conserved protein UCP033563 L21SP3_RS02770 56d5f9cdf271669481a461bbee7e8dcb 180 SUPERFAMILY SSF56784 8 177 8.95E-35 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS02770 56d5f9cdf271669481a461bbee7e8dcb 180 Pfam PF13242 HAD-hyrolase-like 103 170 2.7E-6 T 09-03-2017 L21SP3_RS02770 56d5f9cdf271669481a461bbee7e8dcb 180 PIRSF PIRSF004682 3 177 1.4E-47 T 09-03-2017 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 L21SP3_RS02770 56d5f9cdf271669481a461bbee7e8dcb 180 Gene3D G3DSA:3.40.50.1000 8 177 1.1E-41 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS02770 56d5f9cdf271669481a461bbee7e8dcb 180 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 9 147 8.5E-27 T 09-03-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 L21SP3_RS02770 56d5f9cdf271669481a461bbee7e8dcb 180 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 9 148 1.6E-34 T 09-03-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 L21SP3_RS07045 83226854416f6df45e7dc3065b35f7ae 495 TIGRFAM TIGR03790 TIGR03790: TIGR03790 family protein 252 481 7.3E-46 T 09-03-2017 IPR022265 Conserved hypothetical protein CHP03790 L21SP3_RS00470 8870fcfa8ee6c5893d15dbec6ca67248 855 Pfam PF02065 Melibiase 501 578 2.2E-6 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 L21SP3_RS00470 8870fcfa8ee6c5893d15dbec6ca67248 855 Gene3D G3DSA:3.20.20.70 509 634 3.2E-7 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS00470 8870fcfa8ee6c5893d15dbec6ca67248 855 SUPERFAMILY SSF51445 490 679 6.74E-13 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS01990 714dae30cb98ebdee238818c10173471 540 Pfam PF01609 Transposase DDE domain 200 470 3.2E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS01990 714dae30cb98ebdee238818c10173471 540 SUPERFAMILY SSF53098 160 372 2.81E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS01990 714dae30cb98ebdee238818c10173471 540 SUPERFAMILY SSF53098 410 516 2.81E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS06980 714dae30cb98ebdee238818c10173471 540 Pfam PF01609 Transposase DDE domain 200 470 3.2E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS06980 714dae30cb98ebdee238818c10173471 540 SUPERFAMILY SSF53098 160 372 2.81E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS06980 714dae30cb98ebdee238818c10173471 540 SUPERFAMILY SSF53098 410 516 2.81E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS02620 36e9681434c8ccca063197db635f8b6f 313 SMART SM00244 21 190 8.8E-15 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS02620 36e9681434c8ccca063197db635f8b6f 313 SUPERFAMILY SSF117892 56 196 2.35E-15 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS02620 36e9681434c8ccca063197db635f8b6f 313 Pfam PF01145 SPFH domain / Band 7 family 25 199 6.4E-24 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS02620 36e9681434c8ccca063197db635f8b6f 313 PIRSF PIRSF005651 1 297 1.0E-59 T 09-03-2017 IPR010200 HflC GO:0016021|GO:0052547 L21SP3_RS03495 f61941efd3f6ef201d7c1993036c2a2b 414 Pfam PF09594 Protein of unknown function (DUF2029) 74 305 6.2E-9 T 09-03-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 L21SP3_RS06880 92866a7041ba85c9a937f7cd4ffbf458 552 SUPERFAMILY SSF53649 44 539 2.62E-105 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS06880 92866a7041ba85c9a937f7cd4ffbf458 552 Pfam PF00884 Sulfatase 46 430 1.7E-55 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS06880 92866a7041ba85c9a937f7cd4ffbf458 552 Gene3D G3DSA:3.30.1120.10 480 540 3.4E-14 T 09-03-2017 L21SP3_RS06880 92866a7041ba85c9a937f7cd4ffbf458 552 Gene3D G3DSA:3.40.720.10 43 457 5.0E-90 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS06880 92866a7041ba85c9a937f7cd4ffbf458 552 ProSitePatterns PS00523 Sulfatases signature 1. 92 104 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS02190 84c6ac8c364f94d05a0af801a4b8c0ec 452 Gene3D G3DSA:1.10.579.10 293 445 3.4E-14 T 09-03-2017 L21SP3_RS02190 84c6ac8c364f94d05a0af801a4b8c0ec 452 SUPERFAMILY SSF52425 21 166 1.14E-29 T 09-03-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 L21SP3_RS02190 84c6ac8c364f94d05a0af801a4b8c0ec 452 SUPERFAMILY SSF48173 210 445 4.32E-52 T 09-03-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 L21SP3_RS02190 84c6ac8c364f94d05a0af801a4b8c0ec 452 Gene3D G3DSA:3.40.50.620 22 134 4.2E-15 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS02190 84c6ac8c364f94d05a0af801a4b8c0ec 452 Pfam PF00875 DNA photolyase 22 165 1.1E-22 T 09-03-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 L21SP3_RS02190 84c6ac8c364f94d05a0af801a4b8c0ec 452 Gene3D G3DSA:1.25.40.80 218 292 1.0E-26 T 09-03-2017 L21SP3_RS09880 dae989678195e1f705b015fc5cf38857 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 44 1.0E-7 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS09880 dae989678195e1f705b015fc5cf38857 186 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 52 89 0.004 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS09880 dae989678195e1f705b015fc5cf38857 186 SUPERFAMILY SSF51161 7 149 1.29E-31 T 09-03-2017 IPR011004 Trimeric LpxA-like L21SP3_RS09880 dae989678195e1f705b015fc5cf38857 186 Gene3D G3DSA:2.160.10.10 9 178 7.3E-34 T 09-03-2017 L21SP3_RS09395 627ce3fabb467ca29bce99b19cde1f86 312 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 24 104 3.4E-13 T 09-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 L21SP3_RS09395 627ce3fabb467ca29bce99b19cde1f86 312 Pfam PF00589 Phage integrase family 132 298 4.7E-43 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP3_RS09395 627ce3fabb467ca29bce99b19cde1f86 312 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 21 312 49.031 T 09-03-2017 IPR023009 Tyrosine recombinase XerC/XerD L21SP3_RS09395 627ce3fabb467ca29bce99b19cde1f86 312 Gene3D G3DSA:1.10.150.130 23 112 1.9E-19 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal L21SP3_RS09395 627ce3fabb467ca29bce99b19cde1f86 312 Gene3D G3DSA:1.10.443.10 127 302 4.5E-55 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP3_RS09395 627ce3fabb467ca29bce99b19cde1f86 312 SUPERFAMILY SSF56349 24 303 7.65E-54 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 L21SP3_RS02285 3bedf3c9f5048761febd0d7ca5265f3d 1256 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 672 845 2.5E-24 T 09-03-2017 IPR024618 Domain of unknown function DUF3857 L21SP3_RS02285 3bedf3c9f5048761febd0d7ca5265f3d 1256 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 58 230 5.6E-17 T 09-03-2017 IPR024618 Domain of unknown function DUF3857 L21SP3_RS02285 3bedf3c9f5048761febd0d7ca5265f3d 1256 SUPERFAMILY SSF54001 231 396 3.04E-16 T 09-03-2017 L21SP3_RS02285 3bedf3c9f5048761febd0d7ca5265f3d 1256 Pfam PF01841 Transglutaminase-like superfamily 281 354 1.5E-9 T 09-03-2017 IPR002931 Transglutaminase-like L21SP3_RS02740 4a9701b7df9738b783c0208ea62ddffd 442 Gene3D G3DSA:1.20.1250.20 20 217 2.9E-15 T 09-03-2017 L21SP3_RS02740 4a9701b7df9738b783c0208ea62ddffd 442 Gene3D G3DSA:1.20.1250.20 239 433 9.8E-16 T 09-03-2017 L21SP3_RS02740 4a9701b7df9738b783c0208ea62ddffd 442 Pfam PF07690 Major Facilitator Superfamily 29 382 5.5E-24 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 L21SP3_RS02740 4a9701b7df9738b783c0208ea62ddffd 442 SUPERFAMILY SSF103473 12 429 1.96E-42 T 09-03-2017 IPR020846 Major facilitator superfamily domain L21SP3_RS02255 7bfa1f049fe114a14e891a9f17db634f 576 Pfam PF08305 NPCBM/NEW2 domain 429 548 1.8E-4 T 09-03-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module L21SP3_RS02255 7bfa1f049fe114a14e891a9f17db634f 576 Pfam PF04773 FecR protein 205 264 1.2E-4 T 09-03-2017 IPR006860 FecR protein L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 60 231 2.1E-42 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 Gene3D G3DSA:2.60.40.320 220 339 1.6E-22 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 PRINTS PR00132 Glycosyl hydrolase family 2 signature 159 174 7.6E-26 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 PRINTS PR00132 Glycosyl hydrolase family 2 signature 350 364 7.6E-26 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 PRINTS PR00132 Glycosyl hydrolase family 2 signature 528 543 7.6E-26 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 PRINTS PR00132 Glycosyl hydrolase family 2 signature 381 399 7.6E-26 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 PRINTS PR00132 Glycosyl hydrolase family 2 signature 449 464 7.6E-26 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 SUPERFAMILY SSF49303 234 339 1.01E-17 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 Pfam PF00703 Glycosyl hydrolases family 2 234 339 8.7E-15 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 Gene3D G3DSA:2.70.98.10 740 1036 1.4E-68 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 Gene3D G3DSA:3.20.20.80 341 618 3.1E-79 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 SUPERFAMILY SSF74650 763 1035 1.88E-60 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 SUPERFAMILY SSF51445 342 621 6.43E-74 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 Pfam PF02929 Beta galactosidase small chain 758 1033 2.1E-56 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 SUPERFAMILY SSF49785 22 232 1.46E-59 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 Gene3D G3DSA:2.60.120.260 19 219 6.9E-72 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 342 624 3.6E-73 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 SUPERFAMILY SSF49303 619 725 3.17E-22 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 Gene3D G3DSA:2.60.40.320 630 725 8.8E-24 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 SMART SM01038 749 1034 6.8E-68 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS07985 cef49f1cb8306ccc5e4b7b31efe39a57 1038 Pfam PF16353 Domain of unknown function(DUF4981) 636 724 1.9E-19 T 09-03-2017 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 L21SP3_RS04570 393871eef035e90842237e2ae2479dcd 569 Gene3D G3DSA:3.30.1120.10 480 561 1.2E-23 T 09-03-2017 L21SP3_RS04570 393871eef035e90842237e2ae2479dcd 569 Pfam PF00884 Sulfatase 42 450 2.0E-74 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS04570 393871eef035e90842237e2ae2479dcd 569 Gene3D G3DSA:3.40.720.10 40 479 1.7E-119 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS04570 393871eef035e90842237e2ae2479dcd 569 ProSitePatterns PS00149 Sulfatases signature 2. 137 147 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS04570 393871eef035e90842237e2ae2479dcd 569 SUPERFAMILY SSF53649 384 560 4.51E-142 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS04570 393871eef035e90842237e2ae2479dcd 569 SUPERFAMILY SSF53649 40 354 4.51E-142 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS04255 1ebefdd2c821ec231aeaf8b0b1fe3c53 64 Pfam PF03884 Domain of unknown function (DUF329) 11 56 1.4E-16 T 09-03-2017 IPR005584 DNA gyrase inhibitor YacG GO:0008270 L21SP3_RS04255 1ebefdd2c821ec231aeaf8b0b1fe3c53 64 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 6 63 15.174 T 09-03-2017 IPR005584 DNA gyrase inhibitor YacG GO:0008270 L21SP3_RS04255 1ebefdd2c821ec231aeaf8b0b1fe3c53 64 SUPERFAMILY SSF57716 9 58 7.41E-15 T 09-03-2017 L21SP3_RS04255 1ebefdd2c821ec231aeaf8b0b1fe3c53 64 Gene3D G3DSA:3.30.50.10 6 57 2.8E-18 T 09-03-2017 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 L21SP3_RS00815 277eed151ab6da6c92e9337d84d1e017 673 Pfam PF07971 Glycosyl hydrolase family 92 185 377 1.2E-31 T 09-03-2017 IPR012939 Glycosyl hydrolase family 92 L21SP3_RS00815 277eed151ab6da6c92e9337d84d1e017 673 Pfam PF07971 Glycosyl hydrolase family 92 382 653 3.5E-55 T 09-03-2017 IPR012939 Glycosyl hydrolase family 92 L21SP3_RS00815 277eed151ab6da6c92e9337d84d1e017 673 SUPERFAMILY SSF48208 211 641 2.72E-11 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS00815 277eed151ab6da6c92e9337d84d1e017 673 Gene3D G3DSA:1.20.1610.10 380 498 2.0E-20 T 09-03-2017 L21SP3_RS00815 277eed151ab6da6c92e9337d84d1e017 673 Gene3D G3DSA:3.30.2080.10 499 664 2.3E-49 T 09-03-2017 L21SP3_RS00815 277eed151ab6da6c92e9337d84d1e017 673 Gene3D G3DSA:1.20.1050.60 296 379 9.1E-8 T 09-03-2017 L21SP3_RS00815 277eed151ab6da6c92e9337d84d1e017 673 Gene3D G3DSA:2.70.98.10 1 265 7.9E-59 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 L21SP3_RS10475 7bda5600921cdfceb1f946f30c252be4 331 ProSitePatterns PS00018 EF-hand calcium-binding domain. 310 322 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS10475 7bda5600921cdfceb1f946f30c252be4 331 Gene3D G3DSA:1.10.1330.10 280 330 5.8E-9 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS10475 7bda5600921cdfceb1f946f30c252be4 331 Pfam PF07581 The GLUG motif 98 125 0.0021 T 09-03-2017 IPR011493 GLUG L21SP3_RS10475 7bda5600921cdfceb1f946f30c252be4 331 Pfam PF07581 The GLUG motif 160 182 0.0019 T 09-03-2017 IPR011493 GLUG L21SP3_RS10475 7bda5600921cdfceb1f946f30c252be4 331 ProSitePatterns PS00018 EF-hand calcium-binding domain. 282 294 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS10475 7bda5600921cdfceb1f946f30c252be4 331 SUPERFAMILY SSF63446 279 329 2.09E-7 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS09820 b3d03629b10c4c878757865aaa89ccd1 139 SUPERFAMILY SSF52788 3 137 2.22E-38 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP3_RS09820 b3d03629b10c4c878757865aaa89ccd1 139 Gene3D G3DSA:3.40.50.270 2 137 2.0E-41 T 09-03-2017 L21SP3_RS09820 b3d03629b10c4c878757865aaa89ccd1 139 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 136 6.9E-19 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP3_RS09820 b3d03629b10c4c878757865aaa89ccd1 139 SMART SM00226 4 138 2.2E-28 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily L21SP3_RS07735 b5969b2127914b23c2209786a3062096 471 Gene3D G3DSA:3.40.50.10190 372 460 5.0E-5 T 09-03-2017 IPR001357 BRCT domain L21SP3_RS09500 23d3db3b1efb614fa0e00ac9f4b64b8f 90 TIGRFAM TIGR03382 GC_trans_RRR: Myxococcales GC_trans_RRR domain 70 88 0.0035 T 09-03-2017 IPR017756 Transmembrane Gly-Cys-Arg, conserved site L21SP3_RS09500 23d3db3b1efb614fa0e00ac9f4b64b8f 90 Pfam PF07589 PEP-CTERM motif 67 88 2.6E-7 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS09500 23d3db3b1efb614fa0e00ac9f4b64b8f 90 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 67 90 6.3E-7 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS01285 49c404605b9a9be42057be9c5dc691c1 499 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 104 379 6.1E-56 T 09-03-2017 IPR005181 Sialate O-acetylesterase domain L21SP3_RS01285 49c404605b9a9be42057be9c5dc691c1 499 SUPERFAMILY SSF52266 104 205 2.66E-42 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS01285 49c404605b9a9be42057be9c5dc691c1 499 SUPERFAMILY SSF52266 263 441 2.66E-42 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain L21SP3_RS04310 06a3f58e7482c6399c5fe99701a91d42 124 Pfam PF13453 Transcription factor zinc-finger 61 100 1.9E-8 T 09-03-2017 IPR027392 Transcription factor zinc-finger L21SP3_RS04310 06a3f58e7482c6399c5fe99701a91d42 124 Pfam PF13453 Transcription factor zinc-finger 3 39 5.1E-16 T 09-03-2017 IPR027392 Transcription factor zinc-finger L21SP3_RS04310 06a3f58e7482c6399c5fe99701a91d42 124 Gene3D G3DSA:3.30.40.10 2 71 3.4E-4 T 09-03-2017 IPR013083 Zinc finger, RING/FYVE/PHD-type L21SP3_RS11730 3d498bb652afb3913053eba70bcde548 407 Pfam PF03773 Predicted permease 2 293 2.3E-46 T 09-03-2017 IPR005524 Predicted permease DUF318 L21SP3_RS05375 63a765da019d711858e7ed56f92d1437 762 Gene3D G3DSA:1.50.10.10 369 670 5.6E-14 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS05375 63a765da019d711858e7ed56f92d1437 762 SUPERFAMILY SSF48208 366 670 2.09E-28 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS01940 8e24767ce2f49cca68d802da56bfd124 488 Pfam PF16347 Domain of unknown function (DUF4976) 368 442 1.1E-7 T 09-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 L21SP3_RS01940 8e24767ce2f49cca68d802da56bfd124 488 Gene3D G3DSA:3.40.720.10 33 375 3.8E-104 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS01940 8e24767ce2f49cca68d802da56bfd124 488 Pfam PF00884 Sulfatase 35 361 1.2E-63 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS01940 8e24767ce2f49cca68d802da56bfd124 488 ProSitePatterns PS00523 Sulfatases signature 1. 82 94 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS01940 8e24767ce2f49cca68d802da56bfd124 488 Gene3D G3DSA:3.30.1120.10 376 461 6.1E-16 T 09-03-2017 L21SP3_RS01940 8e24767ce2f49cca68d802da56bfd124 488 SUPERFAMILY SSF53649 34 465 1.6E-119 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS06835 b7c354263e0263ad4c3786af9e005996 114 Pfam PF13298 DNA polymerase Ligase (LigD) 8 80 1.3E-8 T 09-03-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain L21SP3_RS01820 5d5305ceb092c2085db37f1e0af75310 431 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 2 431 53.056 T 09-03-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 L21SP3_RS01820 5d5305ceb092c2085db37f1e0af75310 431 Pfam PF01964 Radical SAM ThiC family 3 425 1.3E-183 T 09-03-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 L21SP3_RS01820 5d5305ceb092c2085db37f1e0af75310 431 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 2 428 2.2E-182 T 09-03-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 L21SP3_RS07200 e20ac7f25c151901d62b9059db38d129 170 SUPERFAMILY SSF56349 65 152 4.12E-8 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 L21SP3_RS07200 e20ac7f25c151901d62b9059db38d129 170 Gene3D G3DSA:1.10.150.130 66 149 3.6E-4 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal L21SP3_RS05815 bb032203e9373e65c6f12707fc97a8a2 59 SUPERFAMILY SSF117130 1 54 1.7E-19 T 09-03-2017 L21SP3_RS05815 bb032203e9373e65c6f12707fc97a8a2 59 Pfam PF02599 Global regulator protein family 1 52 9.9E-26 T 09-03-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 L21SP3_RS05815 bb032203e9373e65c6f12707fc97a8a2 59 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 57 6.1E-23 T 09-03-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 L21SP3_RS00425 d16ea22f56aa9d18b2edde503bd1e152 286 Pfam PF13614 AAA domain 17 192 3.5E-61 T 09-03-2017 IPR025669 AAA domain L21SP3_RS00425 d16ea22f56aa9d18b2edde503bd1e152 286 SUPERFAMILY SSF52540 17 277 3.29E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00425 d16ea22f56aa9d18b2edde503bd1e152 286 Gene3D G3DSA:3.40.50.300 19 275 1.0E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS03545 a9b7538977a8de0afa630d8ffaeab68d 291 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 291 36.817 T 09-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 L21SP3_RS03545 a9b7538977a8de0afa630d8ffaeab68d 291 Gene3D G3DSA:3.10.310.10 1 134 1.1E-49 T 09-03-2017 L21SP3_RS03545 a9b7538977a8de0afa630d8ffaeab68d 291 SUPERFAMILY SSF54506 157 288 9.87E-48 T 09-03-2017 L21SP3_RS03545 a9b7538977a8de0afa630d8ffaeab68d 291 SUPERFAMILY SSF54506 1 146 1.1E-37 T 09-03-2017 L21SP3_RS03545 a9b7538977a8de0afa630d8ffaeab68d 291 Gene3D G3DSA:3.10.310.10 135 279 1.5E-50 T 09-03-2017 L21SP3_RS03545 a9b7538977a8de0afa630d8ffaeab68d 291 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 62 76 - T 09-03-2017 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 L21SP3_RS03545 a9b7538977a8de0afa630d8ffaeab68d 291 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 289 3.5E-85 T 09-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 L21SP3_RS03545 a9b7538977a8de0afa630d8ffaeab68d 291 Pfam PF01678 Diaminopimelate epimerase 169 282 1.3E-30 T 09-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 L21SP3_RS03545 a9b7538977a8de0afa630d8ffaeab68d 291 Pfam PF01678 Diaminopimelate epimerase 3 138 1.8E-27 T 09-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 L21SP3_RS11210 7e6a2daf9cc9b14d0d6386d5b763feab 487 Gene3D G3DSA:3.40.720.10 30 396 7.2E-113 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS11210 7e6a2daf9cc9b14d0d6386d5b763feab 487 Gene3D G3DSA:3.30.1120.10 399 481 1.2E-22 T 09-03-2017 L21SP3_RS11210 7e6a2daf9cc9b14d0d6386d5b763feab 487 Pfam PF16347 Domain of unknown function (DUF4976) 381 474 2.7E-10 T 09-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 L21SP3_RS11210 7e6a2daf9cc9b14d0d6386d5b763feab 487 Pfam PF00884 Sulfatase 33 374 2.8E-73 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS11210 7e6a2daf9cc9b14d0d6386d5b763feab 487 SUPERFAMILY SSF53649 31 475 1.6E-130 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS06915 2cec18133ac3454ace68ee74f10f479d 170 Pfam PF02472 Biopolymer transport protein ExbD/TolR 14 145 1.4E-9 T 09-03-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 L21SP3_RS09670 812734184191b85f2c5c104ffcbd3164 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 185 2.9E-39 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS09670 812734184191b85f2c5c104ffcbd3164 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 179 1.1E-6 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP3_RS09670 812734184191b85f2c5c104ffcbd3164 217 Gene3D G3DSA:3.40.50.1000 76 214 2.3E-37 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS09670 812734184191b85f2c5c104ffcbd3164 217 Gene3D G3DSA:1.10.150.240 19 75 2.3E-13 T 09-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 L21SP3_RS09670 812734184191b85f2c5c104ffcbd3164 217 SUPERFAMILY SSF56784 1 215 6.27E-59 T 09-03-2017 IPR023214 HAD-like domain L21SP3_RS09670 812734184191b85f2c5c104ffcbd3164 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.7E-8 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP3_RS09670 812734184191b85f2c5c104ffcbd3164 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 1.7E-8 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP3_RS09670 812734184191b85f2c5c104ffcbd3164 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 167 1.7E-8 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP3_RS09670 812734184191b85f2c5c104ffcbd3164 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 187 1.7E-8 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 L21SP3_RS10555 48c956cc7d19b7880de9cee52e27474d 383 SUPERFAMILY SSF48208 7 381 3.29E-85 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS10555 48c956cc7d19b7880de9cee52e27474d 383 Gene3D G3DSA:1.50.10.10 3 381 1.7E-108 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS10555 48c956cc7d19b7880de9cee52e27474d 383 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 34 373 9.4E-52 T 09-03-2017 L21SP3_RS02160 3253f881d7de9fd729308dff9b04c0f9 540 Pfam PF01609 Transposase DDE domain 200 470 3.2E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS02160 3253f881d7de9fd729308dff9b04c0f9 540 SUPERFAMILY SSF53098 160 372 2.81E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS02160 3253f881d7de9fd729308dff9b04c0f9 540 SUPERFAMILY SSF53098 410 516 2.81E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS01185 4e52b981edecff61448382aaeff00bf6 67 Pfam PF14213 Domain of unknown function (DUF4325) 20 66 7.9E-12 T 09-03-2017 IPR025474 Domain of unknown function DUF4325 L21SP3_RS11775 adb64cb42b4c1f5317c979168fb14aea 615 Gene3D G3DSA:3.40.50.620 1 260 5.9E-40 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS11775 adb64cb42b4c1f5317c979168fb14aea 615 SUPERFAMILY SSF52467 488 608 3.82E-32 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain L21SP3_RS11775 adb64cb42b4c1f5317c979168fb14aea 615 Pfam PF01012 Electron transfer flavoprotein domain 288 466 1.9E-25 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 L21SP3_RS11775 adb64cb42b4c1f5317c979168fb14aea 615 Pfam PF01012 Electron transfer flavoprotein domain 28 177 9.0E-24 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 L21SP3_RS11775 adb64cb42b4c1f5317c979168fb14aea 615 Gene3D G3DSA:3.40.50.1220 481 607 9.0E-39 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain L21SP3_RS11775 adb64cb42b4c1f5317c979168fb14aea 615 SUPERFAMILY SSF52402 1 248 1.53E-33 T 09-03-2017 L21SP3_RS11775 adb64cb42b4c1f5317c979168fb14aea 615 SMART SM00893 287 472 5.8E-13 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 L21SP3_RS11775 adb64cb42b4c1f5317c979168fb14aea 615 SMART SM00893 25 224 2.2E-13 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 L21SP3_RS11775 adb64cb42b4c1f5317c979168fb14aea 615 Gene3D G3DSA:3.40.50.620 286 475 8.9E-42 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS11775 adb64cb42b4c1f5317c979168fb14aea 615 SUPERFAMILY SSF52402 288 477 3.35E-32 T 09-03-2017 L21SP3_RS11775 adb64cb42b4c1f5317c979168fb14aea 615 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 489 574 2.9E-25 T 09-03-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 L21SP3_RS08080 f898259748fc3545c973d84d6cd80e5c 242 SMART SM00646 129 239 2.3E-31 T 09-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 L21SP3_RS08080 f898259748fc3545c973d84d6cd80e5c 242 SUPERFAMILY SSF53187 66 242 4.39E-47 T 09-03-2017 L21SP3_RS08080 f898259748fc3545c973d84d6cd80e5c 242 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 69 239 3.1E-49 T 09-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 L21SP3_RS08080 f898259748fc3545c973d84d6cd80e5c 242 Gene3D G3DSA:3.40.630.40 66 241 1.4E-53 T 09-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 L21SP3_RS00730 05245449ed14e7f9539d4326c0b21faf 409 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 354 378 - T 09-03-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 L21SP3_RS00730 05245449ed14e7f9539d4326c0b21faf 409 Pfam PF01098 Cell cycle protein 16 396 3.1E-85 T 09-03-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 L21SP3_RS06830 5b34803d8efb6aafa2786757e805da42 267 Pfam PF03649 Uncharacterised protein family (UPF0014) 11 247 1.1E-72 T 09-03-2017 IPR005226 UPF0014 family L21SP3_RS01120 92cf02edf251e2223ae3b624d9145ea8 101 Pfam PF01909 Nucleotidyltransferase domain 11 86 1.2E-9 T 09-03-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 L21SP3_RS01120 92cf02edf251e2223ae3b624d9145ea8 101 Gene3D G3DSA:3.30.460.10 5 95 3.7E-19 T 09-03-2017 L21SP3_RS01120 92cf02edf251e2223ae3b624d9145ea8 101 SUPERFAMILY SSF81301 6 97 1.05E-16 T 09-03-2017 L21SP3_RS10875 c26a389a409746e359d3f02c155c89d3 717 SUPERFAMILY SSF48208 106 395 3.74E-21 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS10875 c26a389a409746e359d3f02c155c89d3 717 Gene3D G3DSA:1.50.10.10 107 276 2.8E-9 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS10875 c26a389a409746e359d3f02c155c89d3 717 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 118 573 4.7E-62 T 09-03-2017 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP3_RS09090 6cbf4d988b2a147fc06de008ca826306 441 SUPERFAMILY SSF56954 3 436 2.62E-63 T 09-03-2017 L21SP3_RS09090 6cbf4d988b2a147fc06de008ca826306 441 Pfam PF02321 Outer membrane efflux protein 35 222 2.1E-22 T 09-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP3_RS09090 6cbf4d988b2a147fc06de008ca826306 441 Pfam PF02321 Outer membrane efflux protein 251 433 4.1E-28 T 09-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP3_RS09090 6cbf4d988b2a147fc06de008ca826306 441 Gene3D G3DSA:1.20.1600.10 25 436 2.1E-57 T 09-03-2017 L21SP3_RS04280 1d0b948f8b54a2c1f5ce28432fea17eb 738 Gene3D G3DSA:2.60.40.760 551 621 9.6E-4 T 09-03-2017 IPR007117 Expansin, cellulose-binding-like domain L21SP3_RS04280 1d0b948f8b54a2c1f5ce28432fea17eb 738 Gene3D G3DSA:2.120.10.30 319 403 1.4E-9 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like L21SP3_RS04280 1d0b948f8b54a2c1f5ce28432fea17eb 738 Gene3D G3DSA:2.120.10.30 191 282 1.4E-9 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like L21SP3_RS04280 1d0b948f8b54a2c1f5ce28432fea17eb 738 SUPERFAMILY SSF63829 342 435 3.07E-14 T 09-03-2017 L21SP3_RS04280 1d0b948f8b54a2c1f5ce28432fea17eb 738 SUPERFAMILY SSF63829 183 281 3.07E-14 T 09-03-2017 L21SP3_RS05175 8b162dd7ed3b2509df1f5db5e7122224 282 Gene3D G3DSA:3.30.1300.10 179 281 2.5E-30 T 09-03-2017 L21SP3_RS05175 8b162dd7ed3b2509df1f5db5e7122224 282 Pfam PF02569 Pantoate-beta-alanine ligase 5 278 3.5E-105 T 09-03-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 L21SP3_RS05175 8b162dd7ed3b2509df1f5db5e7122224 282 SUPERFAMILY SSF52374 2 280 1.31E-104 T 09-03-2017 L21SP3_RS05175 8b162dd7ed3b2509df1f5db5e7122224 282 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 39.493 T 09-03-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 L21SP3_RS05175 8b162dd7ed3b2509df1f5db5e7122224 282 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 280 2.1E-103 T 09-03-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 L21SP3_RS05175 8b162dd7ed3b2509df1f5db5e7122224 282 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 27 67 8.0E-9 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 L21SP3_RS05175 8b162dd7ed3b2509df1f5db5e7122224 282 Gene3D G3DSA:3.40.50.620 1 175 4.5E-77 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold L21SP3_RS02415 01f7efb7aaa47848fe6a0aa8735ab720 144 Pfam PF02082 Transcriptional regulator 1 83 3.6E-26 T 09-03-2017 IPR000944 Transcription regulator Rrf2-type L21SP3_RS02415 01f7efb7aaa47848fe6a0aa8735ab720 144 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 6.7E-35 T 09-03-2017 IPR000944 Transcription regulator Rrf2-type L21SP3_RS02415 01f7efb7aaa47848fe6a0aa8735ab720 144 SUPERFAMILY SSF46785 2 133 9.54E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS02415 01f7efb7aaa47848fe6a0aa8735ab720 144 Gene3D G3DSA:1.10.10.10 1 136 7.3E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS00525 d6d0c33f44a7aaa992f0ce1552f4f20e 743 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 519 716 1.3E-36 T 09-03-2017 IPR005702 Exopolysaccharide synthesis protein GO:0045226 L21SP3_RS00525 d6d0c33f44a7aaa992f0ce1552f4f20e 743 Pfam PF02706 Chain length determinant protein 27 180 1.8E-7 T 09-03-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 L21SP3_RS00525 d6d0c33f44a7aaa992f0ce1552f4f20e 743 SUPERFAMILY SSF52540 538 709 8.36E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00525 d6d0c33f44a7aaa992f0ce1552f4f20e 743 Pfam PF13614 AAA domain 550 694 1.8E-14 T 09-03-2017 IPR025669 AAA domain L21SP3_RS00525 d6d0c33f44a7aaa992f0ce1552f4f20e 743 Gene3D G3DSA:3.40.50.300 538 716 5.5E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06560 2989bda80fb9b2663d57d29a7a9db1e8 216 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 14 189 2.1E-30 T 09-03-2017 IPR018768 Domain of unknown function DUF2344 L21SP3_RS06560 2989bda80fb9b2663d57d29a7a9db1e8 216 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 12 208 2.7E-38 T 09-03-2017 IPR018768 Domain of unknown function DUF2344 L21SP3_RS02615 464fe3a1cb47dea3799a5b00fa55930b 683 SUPERFAMILY SSF117892 412 528 2.62E-6 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS02615 464fe3a1cb47dea3799a5b00fa55930b 683 Pfam PF01145 SPFH domain / Band 7 family 309 537 5.5E-12 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS02615 464fe3a1cb47dea3799a5b00fa55930b 683 SMART SM00244 304 522 0.0018 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS04845 a060c7d44d1801bf3cb3b74d234fb900 376 Gene3D G3DSA:3.40.50.2000 160 329 2.0E-16 T 09-03-2017 L21SP3_RS04845 a060c7d44d1801bf3cb3b74d234fb900 376 SUPERFAMILY SSF53756 130 354 3.72E-42 T 09-03-2017 L21SP3_RS04845 a060c7d44d1801bf3cb3b74d234fb900 376 Pfam PF00534 Glycosyl transferases group 1 165 330 7.1E-28 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS08370 987f9e5918ab977fddae619d764947e3 170 PIRSF PIRSF038996 1 170 1.1E-66 T 09-03-2017 IPR010086 Flavodoxin, long chain GO:0010181 L21SP3_RS08370 987f9e5918ab977fddae619d764947e3 170 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 09-03-2017 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 L21SP3_RS08370 987f9e5918ab977fddae619d764947e3 170 Gene3D G3DSA:3.40.50.360 1 168 6.2E-59 T 09-03-2017 IPR029039 Flavoprotein-like domain L21SP3_RS08370 987f9e5918ab977fddae619d764947e3 170 SUPERFAMILY SSF52218 3 168 2.48E-50 T 09-03-2017 IPR029039 Flavoprotein-like domain L21SP3_RS08370 987f9e5918ab977fddae619d764947e3 170 TIGRFAM TIGR01752 flav_long: flavodoxin 3 168 8.9E-66 T 09-03-2017 IPR010086 Flavodoxin, long chain GO:0010181 L21SP3_RS08370 987f9e5918ab977fddae619d764947e3 170 Pfam PF00258 Flavodoxin 6 160 4.0E-31 T 09-03-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 L21SP3_RS08370 987f9e5918ab977fddae619d764947e3 170 PRINTS PR00369 Flavodoxin signature 5 18 1.0E-7 T 09-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 L21SP3_RS08370 987f9e5918ab977fddae619d764947e3 170 PRINTS PR00369 Flavodoxin signature 81 91 1.0E-7 T 09-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 L21SP3_RS08370 987f9e5918ab977fddae619d764947e3 170 PRINTS PR00369 Flavodoxin signature 52 63 1.0E-7 T 09-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 L21SP3_RS08785 d1f17515832967660ea08b18bdf37c66 282 SUPERFAMILY SSF51621 5 265 7.85E-81 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP3_RS08785 d1f17515832967660ea08b18bdf37c66 282 Pfam PF02548 Ketopantoate hydroxymethyltransferase 5 260 1.8E-87 T 09-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 L21SP3_RS08785 d1f17515832967660ea08b18bdf37c66 282 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 265 33.979 T 09-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 L21SP3_RS08785 d1f17515832967660ea08b18bdf37c66 282 Gene3D G3DSA:3.20.20.60 1 266 1.0E-89 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 L21SP3_RS08785 d1f17515832967660ea08b18bdf37c66 282 PIRSF PIRSF000388 1 268 9.6E-87 T 09-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 L21SP3_RS08785 d1f17515832967660ea08b18bdf37c66 282 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 7 266 3.2E-80 T 09-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 L21SP3_RS07855 d9401e654e9b54509375cb27bab2f12e 631 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 73 239 1.5E-17 T 09-03-2017 L21SP3_RS07855 d9401e654e9b54509375cb27bab2f12e 631 SUPERFAMILY SSF49899 18 244 4.85E-26 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS07855 d9401e654e9b54509375cb27bab2f12e 631 Gene3D G3DSA:2.60.120.200 63 245 2.6E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04225 60b5df1e6c37460b55072bea45713a1d 575 Gene3D G3DSA:3.40.190.10 178 333 1.1E-39 T 09-03-2017 L21SP3_RS04225 60b5df1e6c37460b55072bea45713a1d 575 SUPERFAMILY SSF53850 65 564 2.06E-137 T 09-03-2017 L21SP3_RS04225 60b5df1e6c37460b55072bea45713a1d 575 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 116 484 8.3E-92 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain L21SP3_RS04225 60b5df1e6c37460b55072bea45713a1d 575 PIRSF PIRSF002741 20 571 6.6E-144 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 L21SP3_RS04225 60b5df1e6c37460b55072bea45713a1d 575 Gene3D G3DSA:3.10.105.10 334 540 7.0E-61 T 09-03-2017 L21SP3_RS00655 7ba00166b46f5639f2dcc8652250fad2 178 Pfam PF00156 Phosphoribosyl transferase domain 11 146 5.2E-14 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 L21SP3_RS00655 7ba00166b46f5639f2dcc8652250fad2 178 SUPERFAMILY SSF53271 4 152 4.26E-29 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like L21SP3_RS00655 7ba00166b46f5639f2dcc8652250fad2 178 Gene3D G3DSA:3.40.50.2020 4 150 5.7E-36 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like L21SP3_RS05205 50a4214ee3ab90356ec0cb8783cb5dcd 179 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 156 71.994 T 09-03-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 L21SP3_RS05205 50a4214ee3ab90356ec0cb8783cb5dcd 179 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 5.7E-51 T 09-03-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 L21SP3_RS05205 50a4214ee3ab90356ec0cb8783cb5dcd 179 Pfam PF03477 ATP cone domain 51 137 1.7E-17 T 09-03-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 L21SP3_RS00245 29796d2fdda3b0a5bf3b82ad0af455e9 310 Gene3D G3DSA:3.20.20.20 21 268 7.3E-40 T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 L21SP3_RS00245 29796d2fdda3b0a5bf3b82ad0af455e9 310 SUPERFAMILY SSF51717 36 281 4.45E-33 T 09-03-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 L21SP3_RS00245 29796d2fdda3b0a5bf3b82ad0af455e9 310 Pfam PF00809 Pterin binding enzyme 35 264 1.8E-15 T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 L21SP3_RS10495 492ad94a71eb01a159899ed0d8a224ed 335 Gene3D G3DSA:3.20.20.80 18 215 6.4E-8 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS10495 492ad94a71eb01a159899ed0d8a224ed 335 SUPERFAMILY SSF51445 20 205 3.9E-7 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS10495 492ad94a71eb01a159899ed0d8a224ed 335 Pfam PF14488 Domain of unknown function (DUF4434) 3 169 1.6E-47 T 09-03-2017 IPR027849 Protein of unknown function DUF4434 L21SP3_RS10495 492ad94a71eb01a159899ed0d8a224ed 335 Pfam PF17134 Domain of unknown function (DUF5109) 181 294 2.2E-46 T 09-03-2017 IPR033402 Domain of unknown function DUF5109 L21SP3_RS01535 01562b4eb436d6c4b9f2cc0f63dfa653 161 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 16 153 7.5E-50 T 09-03-2017 L21SP3_RS01535 01562b4eb436d6c4b9f2cc0f63dfa653 161 SUPERFAMILY SSF52833 15 156 9.69E-50 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS01535 01562b4eb436d6c4b9f2cc0f63dfa653 161 PIRSF PIRSF000216 2 161 7.6E-54 T 09-03-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS01535 01562b4eb436d6c4b9f2cc0f63dfa653 161 Gene3D G3DSA:3.40.30.10 73 157 9.3E-15 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS08310 d9d8bd4a072b9e9bc4eaa7659fd6b33f 127 Gene3D G3DSA:1.20.1440.60 19 123 5.1E-5 T 09-03-2017 IPR012657 23S rRNA-intervening sequence protein L21SP3_RS08310 d9d8bd4a072b9e9bc4eaa7659fd6b33f 127 SUPERFAMILY SSF158446 18 123 2.62E-9 T 09-03-2017 L21SP3_RS08310 d9d8bd4a072b9e9bc4eaa7659fd6b33f 127 Pfam PF05635 23S rRNA-intervening sequence protein 18 116 4.8E-8 T 09-03-2017 IPR012657 23S rRNA-intervening sequence protein L21SP3_RS03270 f785175ba44a1e3abd8f25f5d0bfaf49 454 Gene3D G3DSA:2.60.120.200 46 283 9.1E-41 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03270 f785175ba44a1e3abd8f25f5d0bfaf49 454 SUPERFAMILY SSF49899 45 284 3.08E-40 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03270 f785175ba44a1e3abd8f25f5d0bfaf49 454 Pfam PF00722 Glycosyl hydrolases family 16 85 238 3.4E-16 T 09-03-2017 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 L21SP3_RS06840 dc039ab4b2f25f78ce0bae51a434a25b 185 SUPERFAMILY SSF54427 51 168 8.28E-6 T 09-03-2017 IPR032710 NTF2-like domain L21SP3_RS01310 af4368ac737faee18110f533dd832216 434 PIRSF PIRSF000447 1 434 8.9E-138 T 09-03-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 L21SP3_RS01310 af4368ac737faee18110f533dd832216 434 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 276 390 2.7E-35 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal L21SP3_RS01310 af4368ac737faee18110f533dd832216 434 SUPERFAMILY SSF53901 238 433 3.78E-66 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01310 af4368ac737faee18110f533dd832216 434 SUPERFAMILY SSF53901 148 273 2.8E-58 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01310 af4368ac737faee18110f533dd832216 434 SUPERFAMILY SSF53901 3 116 2.8E-58 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01310 af4368ac737faee18110f533dd832216 434 Gene3D G3DSA:3.40.47.10 285 433 4.1E-57 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01310 af4368ac737faee18110f533dd832216 434 Gene3D G3DSA:3.40.47.10 2 279 7.3E-59 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 L21SP3_RS01310 af4368ac737faee18110f533dd832216 434 SMART SM00825 Beta-ketoacyl synthase 5 424 5.7E-15 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain L21SP3_RS01310 af4368ac737faee18110f533dd832216 434 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 268 6.7E-40 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal L21SP3_RS04370 e6097494312f543dae8aeeaa8f66ccec 268 Hamap MF_01805 Segregation and condensation protein A [scpA]. 4 243 20.553 T 09-03-2017 IPR003768 Segregation and condensation protein A L21SP3_RS04370 e6097494312f543dae8aeeaa8f66ccec 268 Pfam PF02616 Segregation and condensation protein ScpA 22 240 7.5E-37 T 09-03-2017 IPR003768 Segregation and condensation protein A L21SP3_RS10995 fe820cea6ee94178afc0183958d1c9a8 931 Gene3D G3DSA:1.10.1330.10 880 922 7.4E-5 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS10995 fe820cea6ee94178afc0183958d1c9a8 931 ProSitePatterns PS00018 EF-hand calcium-binding domain. 908 920 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS10995 fe820cea6ee94178afc0183958d1c9a8 931 Pfam PF07705 CARDB 473 580 1.7E-10 T 09-03-2017 IPR011635 CARDB domain L21SP3_RS08875 77d7bcc1168a84bda742e805606cce3c 223 Gene3D G3DSA:1.10.10.60 3 49 4.3E-19 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS08875 77d7bcc1168a84bda742e805606cce3c 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 9.0E-13 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 L21SP3_RS08875 77d7bcc1168a84bda742e805606cce3c 223 SUPERFAMILY SSF46689 3 67 5.08E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS08875 77d7bcc1168a84bda742e805606cce3c 223 Gene3D G3DSA:1.10.357.10 50 215 2.3E-23 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 L21SP3_RS08875 77d7bcc1168a84bda742e805606cce3c 223 SUPERFAMILY SSF48498 78 212 1.65E-15 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal L21SP3_RS08875 77d7bcc1168a84bda742e805606cce3c 223 Pfam PF09209 Domain of unknown function (DUF1956) 82 211 1.0E-15 T 09-03-2017 IPR015292 Transcription regulator YbiH, C-terminal L21SP3_RS08875 77d7bcc1168a84bda742e805606cce3c 223 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site L21SP3_RS08875 77d7bcc1168a84bda742e805606cce3c 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.0E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 L21SP3_RS08875 77d7bcc1168a84bda742e805606cce3c 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.0E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 L21SP3_RS10710 acf59e334b552be9208eb9f776239cb5 1118 Pfam PF07691 PA14 domain 1025 1114 1.4E-13 T 09-03-2017 IPR011658 PA14 domain L21SP3_RS10710 acf59e334b552be9208eb9f776239cb5 1118 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 561 678 1.6E-8 T 09-03-2017 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 L21SP3_RS10710 acf59e334b552be9208eb9f776239cb5 1118 Gene3D G3DSA:3.90.182.10 1025 1113 1.7E-20 T 09-03-2017 IPR011658 PA14 domain L21SP3_RS10710 acf59e334b552be9208eb9f776239cb5 1118 Pfam PF12215 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term 61 389 6.9E-51 T 09-03-2017 IPR024462 Glycosyl-hydrolase family 116, N-terminal KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 L21SP3_RS10710 acf59e334b552be9208eb9f776239cb5 1118 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 914 962 1.8E-12 T 09-03-2017 L21SP3_RS10710 acf59e334b552be9208eb9f776239cb5 1118 SUPERFAMILY SSF48208 441 816 2.49E-20 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS10710 acf59e334b552be9208eb9f776239cb5 1118 SMART SM00758 983 1118 5.0E-10 T 09-03-2017 IPR011658 PA14 domain L21SP3_RS10710 acf59e334b552be9208eb9f776239cb5 1118 SUPERFAMILY SSF56988 1025 1109 4.18E-17 T 09-03-2017 L21SP3_RS06485 bd33ba0eb373dc22828c03fc12ab303f 496 Gene3D G3DSA:2.115.10.20 163 377 1.5E-4 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS06485 bd33ba0eb373dc22828c03fc12ab303f 496 Gene3D G3DSA:2.115.10.20 103 129 1.5E-4 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS06485 bd33ba0eb373dc22828c03fc12ab303f 496 SUPERFAMILY SSF75005 344 395 2.28E-13 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS06485 bd33ba0eb373dc22828c03fc12ab303f 496 SUPERFAMILY SSF75005 161 315 2.28E-13 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS06485 bd33ba0eb373dc22828c03fc12ab303f 496 SUPERFAMILY SSF75005 96 118 2.28E-13 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS05635 d0b3c0a7578b472f94f827be7fccb009 407 Pfam PF14294 Domain of unknown function (DUF4372) 7 73 1.4E-14 T 09-03-2017 IPR025399 Domain of unknown function DUF4372 L21SP3_RS05635 d0b3c0a7578b472f94f827be7fccb009 407 Pfam PF01609 Transposase DDE domain 131 346 9.8E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS05635 d0b3c0a7578b472f94f827be7fccb009 407 SUPERFAMILY SSF53098 128 377 1.06E-25 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS05635 d0b3c0a7578b472f94f827be7fccb009 407 Gene3D G3DSA:3.90.350.10 255 322 2.9E-4 T 09-03-2017 IPR014736 Transposase, Tn5-like, core L21SP3_RS05290 d0b3c0a7578b472f94f827be7fccb009 407 Pfam PF14294 Domain of unknown function (DUF4372) 7 73 1.4E-14 T 09-03-2017 IPR025399 Domain of unknown function DUF4372 L21SP3_RS05290 d0b3c0a7578b472f94f827be7fccb009 407 Pfam PF01609 Transposase DDE domain 131 346 9.8E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS05290 d0b3c0a7578b472f94f827be7fccb009 407 SUPERFAMILY SSF53098 128 377 1.06E-25 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS05290 d0b3c0a7578b472f94f827be7fccb009 407 Gene3D G3DSA:3.90.350.10 255 322 2.9E-4 T 09-03-2017 IPR014736 Transposase, Tn5-like, core L21SP3_RS05730 c362a52f38d736b570328fb737883b70 434 SMART SM00287 89 157 0.044 T 09-03-2017 IPR003646 SH3-like domain, bacterial-type L21SP3_RS05730 c362a52f38d736b570328fb737883b70 434 SMART SM00287 25 88 0.38 T 09-03-2017 IPR003646 SH3-like domain, bacterial-type L21SP3_RS07215 1c55ed09ac4992127632dffb533f0a8e 85 SUPERFAMILY SSF82771 1 72 7.32E-14 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily L21SP3_RS07215 1c55ed09ac4992127632dffb533f0a8e 85 Pfam PF01541 GIY-YIG catalytic domain 1 68 3.7E-14 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily L21SP3_RS09040 29e24f1ab76503fec31793149c7a8499 333 SUPERFAMILY SSF53448 9 272 8.75E-36 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS09040 29e24f1ab76503fec31793149c7a8499 333 Pfam PF00535 Glycosyl transferase family 2 10 175 1.8E-30 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 L21SP3_RS09040 29e24f1ab76503fec31793149c7a8499 333 Gene3D G3DSA:3.90.550.10 8 138 1.4E-31 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS09215 f0f5a78646e9eb00a15712a8b247e4f3 136 SUPERFAMILY SSF53146 1 113 8.89E-15 T 09-03-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP3_RS09215 f0f5a78646e9eb00a15712a8b247e4f3 136 Gene3D G3DSA:3.30.420.130 1 105 1.7E-10 T 09-03-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP3_RS09215 f0f5a78646e9eb00a15712a8b247e4f3 136 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 10 97 2.5E-5 T 09-03-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP3_RS07205 7c76e9b3f321538fa1b2b6855522a61d 150 Gene3D G3DSA:1.10.443.10 3 143 1.0E-27 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP3_RS07205 7c76e9b3f321538fa1b2b6855522a61d 150 SUPERFAMILY SSF56349 3 136 1.38E-29 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 L21SP3_RS07205 7c76e9b3f321538fa1b2b6855522a61d 150 Pfam PF00589 Phage integrase family 4 133 8.6E-22 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 L21SP3_RS04040 e65e7e909ecdf236bc46ff004a16708d 212 Pfam PF00551 Formyl transferase 5 187 6.7E-39 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP3_RS04040 e65e7e909ecdf236bc46ff004a16708d 212 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 5 196 3.9E-48 T 09-03-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 L21SP3_RS04040 e65e7e909ecdf236bc46ff004a16708d 212 SUPERFAMILY SSF53328 5 199 3.53E-46 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP3_RS04040 e65e7e909ecdf236bc46ff004a16708d 212 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 5 193 23.854 T 09-03-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 L21SP3_RS04040 e65e7e909ecdf236bc46ff004a16708d 212 Gene3D G3DSA:3.40.50.170 5 198 1.2E-49 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 L21SP3_RS01560 fa60303329508f76c980492e8b1374e3 264 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 13 243 4.0E-52 T 09-03-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 L21SP3_RS01560 fa60303329508f76c980492e8b1374e3 264 Gene3D G3DSA:3.40.1210.10 13 256 3.0E-69 T 09-03-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 L21SP3_RS01560 fa60303329508f76c980492e8b1374e3 264 Pfam PF01975 Survival protein SurE 15 196 1.1E-45 T 09-03-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 L21SP3_RS01560 fa60303329508f76c980492e8b1374e3 264 SUPERFAMILY SSF64167 13 257 1.57E-63 T 09-03-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 L21SP3_RS01560 fa60303329508f76c980492e8b1374e3 264 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 13 262 27.396 T 09-03-2017 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 L21SP3_RS07655 292cecb1521593b1ce98cc5074e57fa2 491 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 480 90.212 T 09-03-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 L21SP3_RS07655 292cecb1521593b1ce98cc5074e57fa2 491 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 478 3.6E-188 T 09-03-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 L21SP3_RS07655 292cecb1521593b1ce98cc5074e57fa2 491 SUPERFAMILY SSF75304 1 480 1.57E-155 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 L21SP3_RS07655 292cecb1521593b1ce98cc5074e57fa2 491 Pfam PF01425 Amidase 24 469 3.0E-155 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 L21SP3_RS07655 292cecb1521593b1ce98cc5074e57fa2 491 ProSitePatterns PS00571 Amidases signature. 152 183 - T 09-03-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 L21SP3_RS07655 292cecb1521593b1ce98cc5074e57fa2 491 Gene3D G3DSA:3.90.1300.10 2 483 6.4E-172 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 L21SP3_RS07790 549a89fdc46ff7dd175605698ce7a9c2 388 Gene3D G3DSA:3.60.21.10 69 294 4.8E-30 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS07790 549a89fdc46ff7dd175605698ce7a9c2 388 SUPERFAMILY SSF56300 66 316 5.46E-30 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS07790 549a89fdc46ff7dd175605698ce7a9c2 388 Pfam PF00149 Calcineurin-like phosphoesterase 73 276 2.0E-9 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 L21SP3_RS09285 2d66eeb7f9f4d6f861f5ff11a1b598a3 291 Pfam PF13633 Prokaryotic N-terminal methylation site 3 28 4.9E-8 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS09285 2d66eeb7f9f4d6f861f5ff11a1b598a3 291 SUPERFAMILY SSF54523 5 98 8.63E-16 T 09-03-2017 L21SP3_RS09285 2d66eeb7f9f4d6f861f5ff11a1b598a3 291 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 24 7.2E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS09285 2d66eeb7f9f4d6f861f5ff11a1b598a3 291 PRINTS PR00813 Bacterial general secretion pathway protein G signature 40 58 1.4E-5 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS09285 2d66eeb7f9f4d6f861f5ff11a1b598a3 291 PRINTS PR00813 Bacterial general secretion pathway protein G signature 4 29 1.4E-5 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS09285 2d66eeb7f9f4d6f861f5ff11a1b598a3 291 Gene3D G3DSA:3.30.700.10 5 142 9.9E-7 T 09-03-2017 L21SP3_RS10030 8bf07d9bb94a077d21dfebb4cdafea8a 118 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 97 117 9.6E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS10030 8bf07d9bb94a077d21dfebb4cdafea8a 118 Pfam PF07589 PEP-CTERM motif 97 117 2.2E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS09640 12f2c25f26c986d038e7aeeadc342d93 489 Pfam PF16347 Domain of unknown function (DUF4976) 355 454 4.8E-10 T 09-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 L21SP3_RS09640 12f2c25f26c986d038e7aeeadc342d93 489 Gene3D G3DSA:3.30.1120.10 372 460 2.2E-22 T 09-03-2017 L21SP3_RS09640 12f2c25f26c986d038e7aeeadc342d93 489 SUPERFAMILY SSF53649 33 456 1.05E-121 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS09640 12f2c25f26c986d038e7aeeadc342d93 489 ProSitePatterns PS00523 Sulfatases signature 1. 81 93 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS09640 12f2c25f26c986d038e7aeeadc342d93 489 Pfam PF00884 Sulfatase 35 348 1.8E-63 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS09640 12f2c25f26c986d038e7aeeadc342d93 489 Gene3D G3DSA:3.40.720.10 33 368 1.5E-99 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS03940 77d481264d9b4210be3ae321b44e38c6 785 PIRSF PIRSF007663 16 783 2.0E-260 T 09-03-2017 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51 L21SP3_RS03940 77d481264d9b4210be3ae321b44e38c6 785 SUPERFAMILY SSF48208 275 758 9.86E-91 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS03940 77d481264d9b4210be3ae321b44e38c6 785 Gene3D G3DSA:2.70.98.50 32 405 1.9E-136 T 09-03-2017 IPR027414 Glycosyl hydrolase family, N-terminal domain KEGG: 00511+3.2.1.51 L21SP3_RS03940 77d481264d9b4210be3ae321b44e38c6 785 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 32 266 1.3E-68 T 09-03-2017 IPR027414 Glycosyl hydrolase family, N-terminal domain KEGG: 00511+3.2.1.51 L21SP3_RS09025 961222d373beaf27993aa4d8c0d09c6c 169 Pfam PF01202 Shikimate kinase 13 164 8.8E-35 T 09-03-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 L21SP3_RS09025 961222d373beaf27993aa4d8c0d09c6c 169 Hamap MF_00109 Shikimate kinase [aroK]. 4 167 21.744 T 09-03-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 L21SP3_RS09025 961222d373beaf27993aa4d8c0d09c6c 169 PRINTS PR01100 Shikimate kinase family signature 7 22 3.5E-17 T 09-03-2017 L21SP3_RS09025 961222d373beaf27993aa4d8c0d09c6c 169 PRINTS PR01100 Shikimate kinase family signature 31 44 3.5E-17 T 09-03-2017 L21SP3_RS09025 961222d373beaf27993aa4d8c0d09c6c 169 PRINTS PR01100 Shikimate kinase family signature 97 114 3.5E-17 T 09-03-2017 L21SP3_RS09025 961222d373beaf27993aa4d8c0d09c6c 169 PRINTS PR01100 Shikimate kinase family signature 76 85 3.5E-17 T 09-03-2017 L21SP3_RS09025 961222d373beaf27993aa4d8c0d09c6c 169 Gene3D G3DSA:3.40.50.300 2 167 5.1E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09025 961222d373beaf27993aa4d8c0d09c6c 169 SUPERFAMILY SSF52540 6 162 3.2E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS09065 3c8d26dd4636d2530a2a644d4af6c693 339 Gene3D G3DSA:3.30.70.1140 1 70 1.2E-22 T 09-03-2017 L21SP3_RS09065 3c8d26dd4636d2530a2a644d4af6c693 339 SUPERFAMILY SSF51569 1 337 1.92E-108 T 09-03-2017 L21SP3_RS09065 3c8d26dd4636d2530a2a644d4af6c693 339 Gene3D G3DSA:3.20.20.70 72 337 1.4E-94 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS09065 3c8d26dd4636d2530a2a644d4af6c693 339 Pfam PF00793 DAHP synthetase I family 94 331 1.5E-66 T 09-03-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 L21SP3_RS09065 3c8d26dd4636d2530a2a644d4af6c693 339 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 71 330 3.0E-104 T 09-03-2017 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 L21SP3_RS08580 6ad7ac49f03588152ae23c37d7f656bc 97 ProDom PD027658 PLASMID ISRM30 TRANSPOSASE FOR Y4BD/Y4PK Y4ON NUMBER SEQUENCE INSERTION 42 90 0.003 T 09-03-2017 L21SP3_RS01425 6c503c643f8063da45c2416a2abcb2b2 1018 SUPERFAMILY SSF51126 329 464 4.54E-7 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS01425 6c503c643f8063da45c2416a2abcb2b2 1018 SUPERFAMILY SSF51126 225 281 4.54E-7 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor L21SP3_RS01630 abc0642660fd9d3db270f53ef23c69fd 362 Gene3D G3DSA:3.40.1190.20 1 354 1.4E-74 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS01630 abc0642660fd9d3db270f53ef23c69fd 362 Pfam PF00294 pfkB family carbohydrate kinase 1 333 4.1E-33 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB L21SP3_RS01630 abc0642660fd9d3db270f53ef23c69fd 362 SUPERFAMILY SSF53613 1 351 9.33E-66 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS09280 36a53133cf551c2699c7621ab4358bb0 206 Pfam PF03358 NADPH-dependent FMN reductase 13 123 1.6E-17 T 09-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 L21SP3_RS09280 36a53133cf551c2699c7621ab4358bb0 206 Gene3D G3DSA:3.40.50.360 11 201 9.9E-36 T 09-03-2017 IPR029039 Flavoprotein-like domain L21SP3_RS09280 36a53133cf551c2699c7621ab4358bb0 206 SUPERFAMILY SSF52218 13 204 2.48E-32 T 09-03-2017 IPR029039 Flavoprotein-like domain L21SP3_RS02155 6c6d47ea8ce48398da57c5319388d971 152 SUPERFAMILY SSF51182 27 141 1.33E-14 T 09-03-2017 IPR011051 RmlC-like cupin domain L21SP3_RS02155 6c6d47ea8ce48398da57c5319388d971 152 Gene3D G3DSA:2.60.120.10 33 137 8.9E-12 T 09-03-2017 IPR014710 RmlC-like jelly roll fold L21SP3_RS04640 3978929ac6ee7f4ae0fc90e3e6232052 685 PRINTS PR00811 Bacterial general secretion pathway protein D signature 608 626 1.4E-21 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS04640 3978929ac6ee7f4ae0fc90e3e6232052 685 PRINTS PR00811 Bacterial general secretion pathway protein D signature 474 498 1.4E-21 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS04640 3978929ac6ee7f4ae0fc90e3e6232052 685 PRINTS PR00811 Bacterial general secretion pathway protein D signature 509 519 1.4E-21 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS04640 3978929ac6ee7f4ae0fc90e3e6232052 685 PRINTS PR00811 Bacterial general secretion pathway protein D signature 631 645 1.4E-21 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS04640 3978929ac6ee7f4ae0fc90e3e6232052 685 PRINTS PR00811 Bacterial general secretion pathway protein D signature 401 411 1.4E-21 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS04640 3978929ac6ee7f4ae0fc90e3e6232052 685 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 589 622 - T 09-03-2017 IPR004845 Type II secretion system GspD, conserved site GO:0008565 L21SP3_RS04640 3978929ac6ee7f4ae0fc90e3e6232052 685 Pfam PF00263 Bacterial type II and III secretion system protein 478 642 3.7E-51 T 09-03-2017 IPR004846 Type II/III secretion system GO:0009306 L21SP3_RS04640 3978929ac6ee7f4ae0fc90e3e6232052 685 Pfam PF03958 Bacterial type II/III secretion system short domain 204 303 2.9E-12 T 09-03-2017 IPR005644 NolW-like L21SP3_RS04640 3978929ac6ee7f4ae0fc90e3e6232052 685 Pfam PF03958 Bacterial type II/III secretion system short domain 139 198 7.3E-9 T 09-03-2017 IPR005644 NolW-like L21SP3_RS04640 3978929ac6ee7f4ae0fc90e3e6232052 685 Pfam PF03958 Bacterial type II/III secretion system short domain 309 401 2.8E-12 T 09-03-2017 IPR005644 NolW-like L21SP3_RS04640 3978929ac6ee7f4ae0fc90e3e6232052 685 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 40 652 1.8E-128 T 09-03-2017 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 L21SP3_RS02435 3381c4f05ba59d49bab17dac2dad4ee1 338 Pfam PF07610 Protein of unknown function (DUF1573) 64 107 1.6E-17 T 09-03-2017 IPR011467 Protein of unknown function DUF1573 L21SP3_RS02435 3381c4f05ba59d49bab17dac2dad4ee1 338 Gene3D G3DSA:2.60.40.360 41 138 7.4E-22 T 09-03-2017 IPR008962 PapD-like L21SP3_RS02400 0a7e64899db90c6af2d9514ed017785d 347 Pfam PF03793 PASTA domain 51 113 2.2E-11 T 09-03-2017 IPR005543 PASTA domain L21SP3_RS02400 0a7e64899db90c6af2d9514ed017785d 347 ProSitePatterns PS00018 EF-hand calcium-binding domain. 26 38 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS02400 0a7e64899db90c6af2d9514ed017785d 347 SUPERFAMILY SSF56436 135 158 7.53E-37 T 09-03-2017 IPR016187 C-type lectin fold L21SP3_RS02400 0a7e64899db90c6af2d9514ed017785d 347 SUPERFAMILY SSF56436 205 344 7.53E-37 T 09-03-2017 IPR016187 C-type lectin fold L21SP3_RS02400 0a7e64899db90c6af2d9514ed017785d 347 SMART SM00740 47 114 2.0E-12 T 09-03-2017 IPR005543 PASTA domain L21SP3_RS02400 0a7e64899db90c6af2d9514ed017785d 347 Pfam PF03781 Sulfatase-modifying factor enzyme 1 136 343 1.7E-28 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS02400 0a7e64899db90c6af2d9514ed017785d 347 Gene3D G3DSA:3.90.1580.10 136 345 1.1E-36 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 L21SP3_RS04925 c4a99a94751205742a3348ae0ca65066 271 Gene3D G3DSA:3.40.50.150 219 247 1.3E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS04925 c4a99a94751205742a3348ae0ca65066 271 Gene3D G3DSA:3.40.50.150 32 185 1.3E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS04925 c4a99a94751205742a3348ae0ca65066 271 Pfam PF13649 Methyltransferase domain 63 160 2.0E-14 T 09-03-2017 L21SP3_RS04925 c4a99a94751205742a3348ae0ca65066 271 SUPERFAMILY SSF53335 28 263 1.43E-39 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS10485 d1fefb47092e6f5c06a350946c6576c3 1189 Gene3D G3DSA:2.60.120.200 30 218 1.5E-18 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10485 d1fefb47092e6f5c06a350946c6576c3 1189 Gene3D G3DSA:2.60.120.200 324 522 7.2E-16 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10485 d1fefb47092e6f5c06a350946c6576c3 1189 Gene3D G3DSA:2.60.40.10 240 306 2.8E-6 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS10485 d1fefb47092e6f5c06a350946c6576c3 1189 Gene3D G3DSA:2.60.40.10 839 914 4.7E-4 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS10485 d1fefb47092e6f5c06a350946c6576c3 1189 Gene3D G3DSA:2.60.40.10 544 608 4.1E-4 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS10485 d1fefb47092e6f5c06a350946c6576c3 1189 SUPERFAMILY SSF49899 26 220 3.39E-21 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10485 d1fefb47092e6f5c06a350946c6576c3 1189 SUPERFAMILY SSF49899 328 523 4.19E-19 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10485 d1fefb47092e6f5c06a350946c6576c3 1189 Gene3D G3DSA:2.60.120.200 629 830 3.9E-18 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10485 d1fefb47092e6f5c06a350946c6576c3 1189 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 74 216 2.4E-16 T 09-03-2017 L21SP3_RS10485 d1fefb47092e6f5c06a350946c6576c3 1189 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 384 520 2.5E-11 T 09-03-2017 L21SP3_RS10485 d1fefb47092e6f5c06a350946c6576c3 1189 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 686 821 1.1E-13 T 09-03-2017 L21SP3_RS10485 d1fefb47092e6f5c06a350946c6576c3 1189 SUPERFAMILY SSF49899 629 825 1.24E-20 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS10485 d1fefb47092e6f5c06a350946c6576c3 1189 SUPERFAMILY SSF49265 233 304 5.8E-5 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 L21SP3_RS07305 ba6584f418886549d5cd45788d895ba9 122 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 122 45.015 T 09-03-2017 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 L21SP3_RS07305 ba6584f418886549d5cd45788d895ba9 122 PIRSF PIRSF027377 1 122 1.1E-51 T 09-03-2017 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 L21SP3_RS07305 ba6584f418886549d5cd45788d895ba9 122 Pfam PF14489 QueF-like protein 38 115 2.6E-30 T 09-03-2017 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 L21SP3_RS07305 ba6584f418886549d5cd45788d895ba9 122 Gene3D G3DSA:3.30.1130.10 4 118 4.0E-44 T 09-03-2017 L21SP3_RS07305 ba6584f418886549d5cd45788d895ba9 122 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 5 114 1.2E-47 T 09-03-2017 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 L21SP3_RS07305 ba6584f418886549d5cd45788d895ba9 122 SUPERFAMILY SSF55620 5 109 1.48E-28 T 09-03-2017 L21SP3_RS09935 8cd62d308a696368b57a4aa85093f0f4 615 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 615 38.822 T 09-03-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 L21SP3_RS09935 8cd62d308a696368b57a4aa85093f0f4 615 SUPERFAMILY SSF56235 2 239 6.09E-68 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP3_RS09935 8cd62d308a696368b57a4aa85093f0f4 615 Pfam PF13522 Glutamine amidotransferase domain 66 193 1.1E-16 T 09-03-2017 L21SP3_RS09935 8cd62d308a696368b57a4aa85093f0f4 615 Pfam PF01380 SIS domain 297 424 2.9E-31 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 L21SP3_RS09935 8cd62d308a696368b57a4aa85093f0f4 615 Pfam PF01380 SIS domain 474 597 8.7E-27 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 L21SP3_RS09935 8cd62d308a696368b57a4aa85093f0f4 615 Gene3D G3DSA:3.40.50.10490 449 615 1.3E-63 T 09-03-2017 L21SP3_RS09935 8cd62d308a696368b57a4aa85093f0f4 615 Gene3D G3DSA:3.40.50.10490 249 448 2.6E-77 T 09-03-2017 L21SP3_RS09935 8cd62d308a696368b57a4aa85093f0f4 615 Gene3D G3DSA:3.60.20.10 2 243 1.3E-76 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal L21SP3_RS09935 8cd62d308a696368b57a4aa85093f0f4 615 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 615 1.2E-237 T 09-03-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 L21SP3_RS09935 8cd62d308a696368b57a4aa85093f0f4 615 SUPERFAMILY SSF53697 251 615 2.32E-111 T 09-03-2017 L21SP3_RS00625 1d87b75113f49658debf038da9101cdb 257 Pfam PF06044 Dam-replacing family 2 255 1.2E-111 T 09-03-2017 IPR010324 Dam-replacing L21SP3_RS07090 efd825a9f408432d9f890d3112c0fe1e 1805 Pfam PF05593 RHS Repeat 1249 1283 1.2E-5 T 09-03-2017 IPR031325 RHS repeat L21SP3_RS07090 efd825a9f408432d9f890d3112c0fe1e 1805 Pfam PF05593 RHS Repeat 994 1030 3.9E-6 T 09-03-2017 IPR031325 RHS repeat L21SP3_RS07090 efd825a9f408432d9f890d3112c0fe1e 1805 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1619 1699 1.6E-14 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 L21SP3_RS07090 efd825a9f408432d9f890d3112c0fe1e 1805 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 994 1033 6.2E-6 T 09-03-2017 IPR006530 YD repeat L21SP3_RS01380 0ce1bda68715df69039487b5776e3c40 86 SUPERFAMILY SSF143800 1 77 7.65E-15 T 09-03-2017 L21SP3_RS01380 0ce1bda68715df69039487b5776e3c40 86 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 69 3.8E-17 T 09-03-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS01380 0ce1bda68715df69039487b5776e3c40 86 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 83 16.142 T 09-03-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS01380 0ce1bda68715df69039487b5776e3c40 86 Gene3D G3DSA:4.10.1160.10 38 75 4.7E-14 T 09-03-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS01380 0ce1bda68715df69039487b5776e3c40 86 Pfam PF00830 Ribosomal L28 family 3 70 1.5E-14 T 09-03-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS03120 4c0726cc7eb5db7cd508eacdffab31a0 375 Gene3D G3DSA:3.90.1150.10 249 372 2.7E-28 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS03120 4c0726cc7eb5db7cd508eacdffab31a0 375 SUPERFAMILY SSF53383 5 371 1.09E-109 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS03120 4c0726cc7eb5db7cd508eacdffab31a0 375 PIRSF PIRSF000390 2 374 1.2E-111 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP3_RS03120 4c0726cc7eb5db7cd508eacdffab31a0 375 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 368 1.3E-114 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase L21SP3_RS03120 4c0726cc7eb5db7cd508eacdffab31a0 375 Gene3D G3DSA:3.40.640.10 6 244 1.6E-83 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS10065 214b50415a05a4acb3794ad3aac5b69e 450 Pfam PF02321 Outer membrane efflux protein 272 443 1.3E-18 T 09-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP3_RS10065 214b50415a05a4acb3794ad3aac5b69e 450 Pfam PF02321 Outer membrane efflux protein 64 241 8.1E-22 T 09-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 L21SP3_RS10065 214b50415a05a4acb3794ad3aac5b69e 450 SUPERFAMILY SSF56954 2 445 4.32E-73 T 09-03-2017 L21SP3_RS10065 214b50415a05a4acb3794ad3aac5b69e 450 Gene3D G3DSA:1.20.1600.10 60 445 2.0E-55 T 09-03-2017 L21SP3_RS03030 44167c8a09bd8bcc8cd32bbcd423b9f8 450 PIRSF PIRSF001369 58 450 1.5E-83 T 09-03-2017 IPR024176 Citrate synthase, bacterial-type L21SP3_RS03030 44167c8a09bd8bcc8cd32bbcd423b9f8 450 Pfam PF00285 Citrate synthase, C-terminal domain 43 434 4.1E-111 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 L21SP3_RS03030 44167c8a09bd8bcc8cd32bbcd423b9f8 450 SUPERFAMILY SSF48256 21 439 6.15E-94 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 L21SP3_RS03030 44167c8a09bd8bcc8cd32bbcd423b9f8 450 Gene3D G3DSA:1.10.580.10 21 332 2.7E-72 T 09-03-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 L21SP3_RS03030 44167c8a09bd8bcc8cd32bbcd423b9f8 450 PRINTS PR00143 Citrate synthase signature 253 281 2.7E-29 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 L21SP3_RS03030 44167c8a09bd8bcc8cd32bbcd423b9f8 450 PRINTS PR00143 Citrate synthase signature 403 417 2.7E-29 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 L21SP3_RS03030 44167c8a09bd8bcc8cd32bbcd423b9f8 450 PRINTS PR00143 Citrate synthase signature 230 245 2.7E-29 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 L21SP3_RS03030 44167c8a09bd8bcc8cd32bbcd423b9f8 450 PRINTS PR00143 Citrate synthase signature 383 399 2.7E-29 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 L21SP3_RS03030 44167c8a09bd8bcc8cd32bbcd423b9f8 450 PRINTS PR00143 Citrate synthase signature 174 187 2.7E-29 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 L21SP3_RS09325 43a0260134cc2f7aece365b8363d5641 953 SUPERFAMILY SSF48208 473 551 4.01E-5 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS09325 43a0260134cc2f7aece365b8363d5641 953 Gene3D G3DSA:1.50.10.10 468 554 3.4E-6 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS08165 e3317de549759a9ae674f4afbe57d5cd 126 SUPERFAMILY SSF54637 8 123 3.46E-30 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS08165 e3317de549759a9ae674f4afbe57d5cd 126 Pfam PF03061 Thioesterase superfamily 44 115 4.3E-14 T 09-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 L21SP3_RS08165 e3317de549759a9ae674f4afbe57d5cd 126 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 11 122 2.2E-22 T 09-03-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 L21SP3_RS08165 e3317de549759a9ae674f4afbe57d5cd 126 Gene3D G3DSA:3.10.129.10 6 124 4.6E-37 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS09725 bfc2ffcdf83d071af5926f3b238a49c4 230 SUPERFAMILY SSF53335 64 210 1.35E-29 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS09725 bfc2ffcdf83d071af5926f3b238a49c4 230 Pfam PF13489 Methyltransferase domain 80 187 1.8E-17 T 09-03-2017 L21SP3_RS09725 bfc2ffcdf83d071af5926f3b238a49c4 230 Gene3D G3DSA:3.40.50.150 80 195 2.2E-29 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS07645 fd52528a00f3a17605200a9250120552 97 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 5 97 1.2E-29 T 09-03-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 L21SP3_RS07645 fd52528a00f3a17605200a9250120552 97 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 92 2.3E-21 T 09-03-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 L21SP3_RS07645 fd52528a00f3a17605200a9250120552 97 SUPERFAMILY SSF141000 4 95 3.27E-30 T 09-03-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 L21SP3_RS07645 fd52528a00f3a17605200a9250120552 97 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 4 97 24.214 T 09-03-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 L21SP3_RS03810 e4b4456536c75c8e8113b91d37d53f21 164 Pfam PF02472 Biopolymer transport protein ExbD/TolR 30 88 1.0E-6 T 09-03-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 L21SP3_RS00190 ef5d841b3fa799548c6912b3e7df6650 235 SUPERFAMILY SSF52540 2 222 2.07E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS00190 ef5d841b3fa799548c6912b3e7df6650 235 Pfam PF00005 ABC transporter 18 160 6.6E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS00190 ef5d841b3fa799548c6912b3e7df6650 235 SMART SM00382 26 210 4.6E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS00190 ef5d841b3fa799548c6912b3e7df6650 235 Gene3D G3DSA:3.40.50.300 1 222 4.6E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04295 bdb82f991a7c1d8c065808299150b5ba 419 Pfam PF01435 Peptidase family M48 81 309 2.2E-30 T 09-03-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 L21SP3_RS04295 bdb82f991a7c1d8c065808299150b5ba 419 Gene3D G3DSA:3.30.2010.10 71 160 1.9E-30 T 09-03-2017 L21SP3_RS04295 bdb82f991a7c1d8c065808299150b5ba 419 Hamap MF_00188 Protease HtpX [htpX]. 9 309 25.106 T 09-03-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 L21SP3_RS11330 80e4919b025225b1d51d666036fb979b 173 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 152 171 2.4E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS10295 3632b20472dba41dc90981f5f58962d4 540 Pfam PF01609 Transposase DDE domain 200 470 2.2E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS10295 3632b20472dba41dc90981f5f58962d4 540 SUPERFAMILY SSF53098 160 516 1.74E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS00130 547ab41e4ac8745815b33a0756947627 609 Pfam PF13584 Oxygen tolerance 25 523 6.9E-65 T 09-03-2017 IPR025738 Aerotolerance-related protein BatD L21SP3_RS09815 5ac6cbaf1c66e3439f439124ac58222d 306 Pfam PF00326 Prolyl oligopeptidase family 100 298 1.1E-22 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 L21SP3_RS09815 5ac6cbaf1c66e3439f439124ac58222d 306 SUPERFAMILY SSF53474 43 292 2.34E-47 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS09815 5ac6cbaf1c66e3439f439124ac58222d 306 Gene3D G3DSA:3.40.50.1820 49 294 3.1E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS10310 5ac6cbaf1c66e3439f439124ac58222d 306 Pfam PF00326 Prolyl oligopeptidase family 100 298 1.1E-22 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 L21SP3_RS10310 5ac6cbaf1c66e3439f439124ac58222d 306 SUPERFAMILY SSF53474 43 292 2.34E-47 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS10310 5ac6cbaf1c66e3439f439124ac58222d 306 Gene3D G3DSA:3.40.50.1820 49 294 3.1E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS07370 1d775a6fd0cbd578117a3718d6338527 225 Pfam PF13633 Prokaryotic N-terminal methylation site 8 33 3.0E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS07370 1d775a6fd0cbd578117a3718d6338527 225 Gene3D G3DSA:3.30.700.10 10 65 6.7E-7 T 09-03-2017 L21SP3_RS07370 1d775a6fd0cbd578117a3718d6338527 225 PRINTS PR00813 Bacterial general secretion pathway protein G signature 45 63 1.2E-8 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS07370 1d775a6fd0cbd578117a3718d6338527 225 PRINTS PR00813 Bacterial general secretion pathway protein G signature 9 34 1.2E-8 T 09-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 L21SP3_RS07370 1d775a6fd0cbd578117a3718d6338527 225 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 3.9E-7 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS07370 1d775a6fd0cbd578117a3718d6338527 225 SUPERFAMILY SSF54523 10 70 2.09E-13 T 09-03-2017 L21SP3_RS04555 260d6abff2d0829282a2e24640563004 373 SUPERFAMILY SSF51726 27 299 8.37E-6 T 09-03-2017 L21SP3_RS04555 260d6abff2d0829282a2e24640563004 373 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 29 308 2.5E-6 T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 L21SP3_RS04975 8fe3a2662d38525cc5463c1b2709852e 422 Pfam PF01609 Transposase DDE domain 275 412 1.5E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS04975 8fe3a2662d38525cc5463c1b2709852e 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.6E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS04050 8fe3a2662d38525cc5463c1b2709852e 422 Pfam PF01609 Transposase DDE domain 275 412 1.5E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS04050 8fe3a2662d38525cc5463c1b2709852e 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.6E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS10680 c45eb67b67800a175b27256f97461c60 464 ProSitePatterns PS00217 Sugar transport proteins signature 2. 122 147 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP3_RS10680 c45eb67b67800a175b27256f97461c60 464 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 17 456 9.5E-124 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS10680 c45eb67b67800a175b27256f97461c60 464 ProSitePatterns PS00216 Sugar transport proteins signature 1. 80 97 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP3_RS10680 c45eb67b67800a175b27256f97461c60 464 Gene3D G3DSA:1.20.1250.20 30 217 7.3E-26 T 09-03-2017 L21SP3_RS10680 c45eb67b67800a175b27256f97461c60 464 Gene3D G3DSA:1.20.1250.20 270 455 1.1E-24 T 09-03-2017 L21SP3_RS10680 c45eb67b67800a175b27256f97461c60 464 ProSitePatterns PS00216 Sugar transport proteins signature 1. 320 337 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 L21SP3_RS10680 c45eb67b67800a175b27256f97461c60 464 PRINTS PR00171 Sugar transporter signature 276 286 3.5E-29 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS10680 c45eb67b67800a175b27256f97461c60 464 PRINTS PR00171 Sugar transporter signature 34 44 3.5E-29 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS10680 c45eb67b67800a175b27256f97461c60 464 PRINTS PR00171 Sugar transporter signature 385 397 3.5E-29 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS10680 c45eb67b67800a175b27256f97461c60 464 PRINTS PR00171 Sugar transporter signature 362 383 3.5E-29 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS10680 c45eb67b67800a175b27256f97461c60 464 PRINTS PR00171 Sugar transporter signature 117 136 3.5E-29 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 L21SP3_RS10680 c45eb67b67800a175b27256f97461c60 464 SUPERFAMILY SSF103473 4 456 9.55E-75 T 09-03-2017 IPR020846 Major facilitator superfamily domain L21SP3_RS10680 c45eb67b67800a175b27256f97461c60 464 Pfam PF00083 Sugar (and other) transporter 26 460 5.4E-123 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 L21SP3_RS04540 8e58700b1e990d74806888dbe961e5db 193 Gene3D G3DSA:2.120.10.10 5 188 1.1E-31 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS04540 8e58700b1e990d74806888dbe961e5db 193 Pfam PF13088 BNR repeat-like domain 8 165 1.9E-8 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS04540 8e58700b1e990d74806888dbe961e5db 193 SUPERFAMILY SSF50939 4 191 4.49E-34 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS00050 09e2323b35647b550ab0d44c54db13fe 263 Gene3D G3DSA:3.40.50.150 55 246 4.9E-25 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS00050 09e2323b35647b550ab0d44c54db13fe 263 Pfam PF13489 Methyltransferase domain 45 225 6.2E-17 T 09-03-2017 L21SP3_RS00050 09e2323b35647b550ab0d44c54db13fe 263 SUPERFAMILY SSF53335 5 227 5.53E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS02235 6ad336f9d93b7c783d4776c4e9f2b3e3 496 Pfam PF00263 Bacterial type II and III secretion system protein 292 452 1.3E-44 T 09-03-2017 IPR004846 Type II/III secretion system GO:0009306 L21SP3_RS02235 6ad336f9d93b7c783d4776c4e9f2b3e3 496 Pfam PF03958 Bacterial type II/III secretion system short domain 133 191 4.9E-7 T 09-03-2017 IPR005644 NolW-like L21SP3_RS02235 6ad336f9d93b7c783d4776c4e9f2b3e3 496 PRINTS PR00811 Bacterial general secretion pathway protein D signature 287 311 4.0E-19 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS02235 6ad336f9d93b7c783d4776c4e9f2b3e3 496 PRINTS PR00811 Bacterial general secretion pathway protein D signature 440 454 4.0E-19 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS02235 6ad336f9d93b7c783d4776c4e9f2b3e3 496 PRINTS PR00811 Bacterial general secretion pathway protein D signature 417 435 4.0E-19 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS02235 6ad336f9d93b7c783d4776c4e9f2b3e3 496 PRINTS PR00811 Bacterial general secretion pathway protein D signature 193 203 4.0E-19 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS02235 6ad336f9d93b7c783d4776c4e9f2b3e3 496 PRINTS PR00811 Bacterial general secretion pathway protein D signature 322 332 4.0E-19 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS10675 bcab69406fdb3c9711ae2116bad54dc5 417 Gene3D G3DSA:3.20.20.210 126 413 2.7E-33 T 09-03-2017 L21SP3_RS10675 bcab69406fdb3c9711ae2116bad54dc5 417 Gene3D G3DSA:3.20.20.210 2 80 2.7E-33 T 09-03-2017 L21SP3_RS10675 bcab69406fdb3c9711ae2116bad54dc5 417 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 217 413 1.7E-16 T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 L21SP3_RS10675 bcab69406fdb3c9711ae2116bad54dc5 417 SUPERFAMILY SSF51726 214 413 8.2E-26 T 09-03-2017 L21SP3_RS07585 b663d8b12a6a5e931907db0b2ea4bf32 204 Pfam PF00293 NUDIX domain 69 176 5.0E-14 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 L21SP3_RS07585 b663d8b12a6a5e931907db0b2ea4bf32 204 Pfam PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal 2 56 3.4E-12 T 09-03-2017 L21SP3_RS07585 b663d8b12a6a5e931907db0b2ea4bf32 204 SUPERFAMILY SSF55811 59 190 3.25E-29 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 L21SP3_RS07585 b663d8b12a6a5e931907db0b2ea4bf32 204 Gene3D G3DSA:3.90.79.10 61 196 4.2E-29 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 L21SP3_RS01860 d9ab85ba0599ff9237cd829802130845 157 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 111 146 - T 09-03-2017 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 L21SP3_RS01860 d9ab85ba0599ff9237cd829802130845 157 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 1 151 2.3E-34 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP3_RS01860 d9ab85ba0599ff9237cd829802130845 157 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 137 149 7.3E-22 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP3_RS01860 d9ab85ba0599ff9237cd829802130845 157 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 105 124 7.3E-22 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP3_RS01860 d9ab85ba0599ff9237cd829802130845 157 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 81 97 7.3E-22 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP3_RS01860 d9ab85ba0599ff9237cd829802130845 157 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 1 14 7.3E-22 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP3_RS01860 d9ab85ba0599ff9237cd829802130845 157 Gene3D G3DSA:3.30.420.10 1 154 1.8E-48 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS01860 d9ab85ba0599ff9237cd829802130845 157 SUPERFAMILY SSF53098 1 152 5.82E-36 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS01860 d9ab85ba0599ff9237cd829802130845 157 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 152 36.811 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP3_RS01860 d9ab85ba0599ff9237cd829802130845 157 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 1 148 3.2E-41 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 L21SP3_RS02945 f5855f725798e10446818d901800b02f 339 Pfam PF16200 C-terminal region of band_7 254 313 8.8E-25 T 09-03-2017 IPR032435 Band 7, C-terminal extension L21SP3_RS02945 f5855f725798e10446818d901800b02f 339 PRINTS PR00721 Stomatin signature 120 137 8.8E-29 T 09-03-2017 IPR001972 Stomatin family GO:0016020 L21SP3_RS02945 f5855f725798e10446818d901800b02f 339 PRINTS PR00721 Stomatin signature 164 182 8.8E-29 T 09-03-2017 IPR001972 Stomatin family GO:0016020 L21SP3_RS02945 f5855f725798e10446818d901800b02f 339 PRINTS PR00721 Stomatin signature 183 204 8.8E-29 T 09-03-2017 IPR001972 Stomatin family GO:0016020 L21SP3_RS02945 f5855f725798e10446818d901800b02f 339 PRINTS PR00721 Stomatin signature 140 163 8.8E-29 T 09-03-2017 IPR001972 Stomatin family GO:0016020 L21SP3_RS02945 f5855f725798e10446818d901800b02f 339 PRINTS PR00721 Stomatin signature 85 106 8.8E-29 T 09-03-2017 IPR001972 Stomatin family GO:0016020 L21SP3_RS02945 f5855f725798e10446818d901800b02f 339 SUPERFAMILY SSF117892 61 195 1.31E-43 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS02945 f5855f725798e10446818d901800b02f 339 SMART SM00244 30 188 2.1E-56 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS02945 f5855f725798e10446818d901800b02f 339 Pfam PF01145 SPFH domain / Band 7 family 34 204 1.3E-28 T 09-03-2017 IPR001107 Band 7 domain L21SP3_RS01565 4bb4101ae3b612b61f336a1affbf8caa 540 Pfam PF00884 Sulfatase 31 419 3.6E-83 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS01565 4bb4101ae3b612b61f336a1affbf8caa 540 SUPERFAMILY SSF53649 29 522 1.28E-150 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS01565 4bb4101ae3b612b61f336a1affbf8caa 540 Gene3D G3DSA:3.30.1120.10 448 529 1.1E-22 T 09-03-2017 L21SP3_RS01565 4bb4101ae3b612b61f336a1affbf8caa 540 Gene3D G3DSA:3.40.720.10 28 446 4.7E-134 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS00955 0504196a2687d0e9b90716e16cbc3401 259 Gene3D G3DSA:3.20.20.80 42 257 1.9E-61 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS00955 0504196a2687d0e9b90716e16cbc3401 259 SUPERFAMILY SSF51445 43 247 1.92E-21 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS00955 0504196a2687d0e9b90716e16cbc3401 259 Pfam PF14587 O-Glycosyl hydrolase family 30 30 256 8.0E-21 T 09-03-2017 L21SP3_RS02215 0b301f51c980e22efa95d6aa378b3c9a 620 Pfam PF00474 Sodium:solute symporter family 416 543 6.4E-13 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS02215 0b301f51c980e22efa95d6aa378b3c9a 620 Pfam PF00474 Sodium:solute symporter family 37 308 5.2E-37 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS00090 9c6204719d51f3748969bcdcb38a0977 540 Gene3D G3DSA:3.20.20.80 53 432 1.7E-77 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS00090 9c6204719d51f3748969bcdcb38a0977 540 Pfam PF14587 O-Glycosyl hydrolase family 30 42 412 1.3E-109 T 09-03-2017 L21SP3_RS00090 9c6204719d51f3748969bcdcb38a0977 540 SUPERFAMILY SSF51445 59 442 2.11E-28 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS00090 9c6204719d51f3748969bcdcb38a0977 540 Gene3D G3DSA:2.60.40.1180 433 539 7.2E-26 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta L21SP3_RS05710 0855848041a9f776a886a57532962d46 475 Gene3D G3DSA:3.40.50.970 27 244 1.1E-53 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS05710 0855848041a9f776a886a57532962d46 475 SUPERFAMILY SSF52518 13 265 1.55E-53 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS05710 0855848041a9f776a886a57532962d46 475 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 305 468 3.6E-36 T 09-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP3_RS05710 0855848041a9f776a886a57532962d46 475 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 62 220 1.4E-23 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 L21SP3_RS05710 0855848041a9f776a886a57532962d46 475 Gene3D G3DSA:3.40.920.10 299 472 1.4E-42 T 09-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP3_RS05710 0855848041a9f776a886a57532962d46 475 SUPERFAMILY SSF53323 298 472 4.32E-35 T 09-03-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 L21SP3_RS06955 b1159b30a5c6bb48739f7528d45ba68d 498 Pfam PF00884 Sulfatase 34 385 2.0E-67 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS06955 b1159b30a5c6bb48739f7528d45ba68d 498 Gene3D G3DSA:3.30.1120.10 423 493 1.1E-21 T 09-03-2017 L21SP3_RS06955 b1159b30a5c6bb48739f7528d45ba68d 498 SUPERFAMILY SSF53649 33 491 5.1E-124 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS06955 b1159b30a5c6bb48739f7528d45ba68d 498 Gene3D G3DSA:3.40.720.10 32 422 1.3E-106 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS00865 06676a9b463d9cbf53b60a502bc6dec3 402 Pfam PF01960 ArgJ family 15 402 9.1E-134 T 09-03-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 L21SP3_RS00865 06676a9b463d9cbf53b60a502bc6dec3 402 Gene3D G3DSA:3.60.70.12 4 275 1.1E-89 T 09-03-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 L21SP3_RS00865 06676a9b463d9cbf53b60a502bc6dec3 402 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 6 402 5.9E-133 T 09-03-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 L21SP3_RS00865 06676a9b463d9cbf53b60a502bc6dec3 402 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 402 129.183 T 09-03-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 L21SP3_RS00865 06676a9b463d9cbf53b60a502bc6dec3 402 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 29 402 7.0E-68 T 09-03-2017 L21SP3_RS00865 06676a9b463d9cbf53b60a502bc6dec3 402 SUPERFAMILY SSF56266 10 399 3.01E-123 T 09-03-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 L21SP3_RS05610 3cae68ffcd08e0c0e9ad22993e18b5e8 253 Gene3D G3DSA:2.50.20.10 18 219 8.2E-7 T 09-03-2017 L21SP3_RS10345 083a1038e9de7590021788bba9f39bfb 316 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 50 286 9.2E-40 T 09-03-2017 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system L21SP3_RS07465 5cde0603e3b7b249b2abc5db79ce8298 475 Pfam PF12566 Protein of unknown function (DUF3748) 104 224 1.2E-35 T 09-03-2017 IPR022223 Protein of unknown function DUF3748 L21SP3_RS07465 5cde0603e3b7b249b2abc5db79ce8298 475 Gene3D G3DSA:2.130.10.10 352 469 2.1E-13 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 L21SP3_RS07465 5cde0603e3b7b249b2abc5db79ce8298 475 Gene3D G3DSA:2.130.10.10 36 126 1.8E-7 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 L21SP3_RS07465 5cde0603e3b7b249b2abc5db79ce8298 475 Pfam PF07676 WD40-like Beta Propeller Repeat 39 63 0.28 T 09-03-2017 IPR011659 WD40-like Beta Propeller L21SP3_RS07465 5cde0603e3b7b249b2abc5db79ce8298 475 SUPERFAMILY SSF82171 169 190 5.1E-8 T 09-03-2017 L21SP3_RS07465 5cde0603e3b7b249b2abc5db79ce8298 475 SUPERFAMILY SSF82171 34 126 5.1E-8 T 09-03-2017 L21SP3_RS07465 5cde0603e3b7b249b2abc5db79ce8298 475 SUPERFAMILY SSF69304 351 452 4.05E-10 T 09-03-2017 L21SP3_RS03100 061a5cc08da118c1e59b30c73f594970 293 Pfam PF01875 Memo-like protein 6 291 2.3E-46 T 09-03-2017 IPR002737 MEMO1 family Reactome: R-HSA-6785631 L21SP3_RS03100 061a5cc08da118c1e59b30c73f594970 293 Gene3D G3DSA:3.40.830.10 142 217 6.9E-4 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 L21SP3_RS03100 061a5cc08da118c1e59b30c73f594970 293 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 4 293 1.2E-63 T 09-03-2017 IPR002737 MEMO1 family Reactome: R-HSA-6785631 L21SP3_RS07610 e804373e8f6e1ab7dfd899007dfe2dc0 137 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 134 2.3E-26 T 09-03-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 L21SP3_RS07250 3d8be777dd6ca659ad9ba8c890306fa9 283 SUPERFAMILY SSF56731 106 256 2.09E-10 T 09-03-2017 L21SP3_RS07250 3d8be777dd6ca659ad9ba8c890306fa9 283 Pfam PF13155 Toprim-like 172 252 5.4E-5 T 09-03-2017 L21SP3_RS07250 3d8be777dd6ca659ad9ba8c890306fa9 283 Gene3D G3DSA:3.40.1360.10 168 273 8.9E-16 T 09-03-2017 L21SP3_RS03955 c0e951e8d54fbf217d510ff1613165a9 360 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 5 356 23.892 T 09-03-2017 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 L21SP3_RS03955 c0e951e8d54fbf217d510ff1613165a9 360 Pfam PF03116 NQR2, RnfD, RnfE family 7 354 2.4E-105 T 09-03-2017 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 L21SP3_RS03955 c0e951e8d54fbf217d510ff1613165a9 360 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 10 351 7.8E-105 T 09-03-2017 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 L21SP3_RS05725 7b6d6bf0ffeee8ebec05b7a41cd4b363 288 SUPERFAMILY SSF56281 31 279 2.84E-36 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS05725 7b6d6bf0ffeee8ebec05b7a41cd4b363 288 Pfam PF12706 Beta-lactamase superfamily domain 43 248 1.7E-14 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS05725 7b6d6bf0ffeee8ebec05b7a41cd4b363 288 Gene3D G3DSA:3.60.15.10 27 279 1.2E-34 T 09-03-2017 IPR001279 Metallo-beta-lactamase L21SP3_RS07695 8fffeddabe0f63817265ec082ce66c0f 148 Gene3D G3DSA:1.10.10.10 9 87 2.2E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS07695 8fffeddabe0f63817265ec082ce66c0f 148 Pfam PF01475 Ferric uptake regulator family 17 134 1.5E-23 T 09-03-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 L21SP3_RS07695 8fffeddabe0f63817265ec082ce66c0f 148 SUPERFAMILY SSF46785 10 139 3.99E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS05040 3afe85be659acf58c5d9dc4742c0f4d4 172 Pfam PF04542 Sigma-70 region 2 13 79 4.0E-10 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS05040 3afe85be659acf58c5d9dc4742c0f4d4 172 SUPERFAMILY SSF88659 105 163 6.35E-8 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS05040 3afe85be659acf58c5d9dc4742c0f4d4 172 SUPERFAMILY SSF88946 11 84 1.62E-12 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS05040 3afe85be659acf58c5d9dc4742c0f4d4 172 Gene3D G3DSA:1.10.10.10 108 164 4.6E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS05040 3afe85be659acf58c5d9dc4742c0f4d4 172 Pfam PF08281 Sigma-70, region 4 108 155 7.7E-7 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS05040 3afe85be659acf58c5d9dc4742c0f4d4 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 163 8.4E-21 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 L21SP3_RS05040 3afe85be659acf58c5d9dc4742c0f4d4 172 Gene3D G3DSA:1.10.1740.10 10 102 3.6E-14 T 09-03-2017 L21SP3_RS05040 3afe85be659acf58c5d9dc4742c0f4d4 172 TIGRFAM TIGR02989 Sig-70_gvs1: RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family 9 164 9.2E-42 T 09-03-2017 IPR014331 RNA polymerase sigma-70 ECF-like, Rhodopirellula baltica L21SP3_RS04380 7a8572b3d0d8e693a4ba1fdfbbd46ba3 151 Gene3D G3DSA:1.10.287.1080 36 118 5.5E-5 T 09-03-2017 L21SP3_RS04380 7a8572b3d0d8e693a4ba1fdfbbd46ba3 151 SUPERFAMILY SSF101386 17 136 2.33E-16 T 09-03-2017 L21SP3_RS04380 7a8572b3d0d8e693a4ba1fdfbbd46ba3 151 Pfam PF08761 dUTPase 17 107 5.5E-10 T 09-03-2017 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 L21SP3_RS05460 ae0b130dfa9db6297cb52026b78d9e20 402 Gene3D G3DSA:2.60.120.200 119 269 1.2E-12 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05460 ae0b130dfa9db6297cb52026b78d9e20 402 SUPERFAMILY SSF49899 102 268 1.13E-13 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05460 ae0b130dfa9db6297cb52026b78d9e20 402 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 116 261 9.1E-13 T 09-03-2017 L21SP3_RS05460 ae0b130dfa9db6297cb52026b78d9e20 402 Gene3D G3DSA:2.60.40.10 291 346 1.6E-4 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS03295 b4fa791a6998b3189351ab70e0aa8386 552 Gene3D G3DSA:2.30.38.10 373 450 4.5E-18 T 09-03-2017 L21SP3_RS03295 b4fa791a6998b3189351ab70e0aa8386 552 Pfam PF00501 AMP-binding enzyme 42 456 3.7E-71 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 L21SP3_RS03295 b4fa791a6998b3189351ab70e0aa8386 552 Gene3D G3DSA:3.40.50.980 212 372 5.1E-26 T 09-03-2017 L21SP3_RS03295 b4fa791a6998b3189351ab70e0aa8386 552 Pfam PF13193 AMP-binding enzyme C-terminal domain 465 543 6.9E-23 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain L21SP3_RS03295 b4fa791a6998b3189351ab70e0aa8386 552 Gene3D G3DSA:3.40.50.980 35 211 5.3E-25 T 09-03-2017 L21SP3_RS03295 b4fa791a6998b3189351ab70e0aa8386 552 Gene3D G3DSA:3.30.300.30 451 551 6.0E-30 T 09-03-2017 L21SP3_RS03295 b4fa791a6998b3189351ab70e0aa8386 552 SUPERFAMILY SSF56801 17 551 1.96E-129 T 09-03-2017 L21SP3_RS01245 9fcfd6d8c1846083cd96df98b98702c2 324 Gene3D G3DSA:3.90.226.10 57 271 1.7E-46 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS01245 9fcfd6d8c1846083cd96df98b98702c2 324 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 8 316 9.2E-126 T 09-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS01245 9fcfd6d8c1846083cd96df98b98702c2 324 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 10 316 45.345 T 09-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS01245 9fcfd6d8c1846083cd96df98b98702c2 324 SUPERFAMILY SSF52096 33 314 1.44E-88 T 09-03-2017 IPR029045 ClpP/crotonase-like domain L21SP3_RS01245 9fcfd6d8c1846083cd96df98b98702c2 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 3.9E-41 T 09-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS01245 9fcfd6d8c1846083cd96df98b98702c2 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 3.9E-41 T 09-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS01245 9fcfd6d8c1846083cd96df98b98702c2 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 3.9E-41 T 09-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS01245 9fcfd6d8c1846083cd96df98b98702c2 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 3.9E-41 T 09-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS01245 9fcfd6d8c1846083cd96df98b98702c2 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 3.9E-41 T 09-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS01245 9fcfd6d8c1846083cd96df98b98702c2 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 3.9E-41 T 09-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS01245 9fcfd6d8c1846083cd96df98b98702c2 324 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 10 147 3.5E-49 T 09-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 L21SP3_RS07340 7d9670bd32c92404915dddc5f9833ad3 216 SUPERFAMILY SSF53335 89 190 4.47E-20 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS07340 7d9670bd32c92404915dddc5f9833ad3 216 Gene3D G3DSA:3.40.50.150 71 195 1.2E-25 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS07340 7d9670bd32c92404915dddc5f9833ad3 216 Pfam PF08241 Methyltransferase domain 87 135 5.6E-15 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 L21SP3_RS07475 3820c205934e59228f8e184d7c3218ae 528 Pfam PF00474 Sodium:solute symporter family 41 476 6.3E-41 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS07475 3820c205934e59228f8e184d7c3218ae 528 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 39 476 1.6E-65 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS06105 9e6fd02421cc19129c7b8c3625ab135e 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 74 87 1.1E-21 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase L21SP3_RS06105 9e6fd02421cc19129c7b8c3625ab135e 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 97 113 1.1E-21 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase L21SP3_RS06105 9e6fd02421cc19129c7b8c3625ab135e 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 201 213 1.1E-21 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase L21SP3_RS06105 9e6fd02421cc19129c7b8c3625ab135e 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 167 179 1.1E-21 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase L21SP3_RS06105 9e6fd02421cc19129c7b8c3625ab135e 258 Pfam PF00557 Metallopeptidase family M24 12 250 1.3E-47 T 09-03-2017 IPR000994 Peptidase M24, structural domain L21SP3_RS06105 9e6fd02421cc19129c7b8c3625ab135e 258 Gene3D G3DSA:3.90.230.10 5 258 7.1E-82 T 09-03-2017 IPR000994 Peptidase M24, structural domain L21SP3_RS06105 9e6fd02421cc19129c7b8c3625ab135e 258 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 257 1.4E-84 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 L21SP3_RS06105 9e6fd02421cc19129c7b8c3625ab135e 258 SUPERFAMILY SSF55920 5 257 3.14E-77 T 09-03-2017 IPR000994 Peptidase M24, structural domain L21SP3_RS06105 9e6fd02421cc19129c7b8c3625ab135e 258 Hamap MF_01974 Methionine aminopeptidase [map]. 3 258 34.938 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 L21SP3_RS10585 22775d3406ac4cdb316c48d37920a40d 114 Pfam PF09719 Putative redox-active protein (C_GCAxxG_C_C) 15 108 6.5E-13 T 09-03-2017 IPR010181 CGCAxxGCC motif L21SP3_RS08420 f80df40c6c46b4a96ea1799d7ba31e51 317 Pfam PF04187 Haem-binding uptake, Tiki superfamily, ChaN 45 254 2.5E-56 T 09-03-2017 IPR007314 Haem-binding uptake, Tiki superfamily, ChaN L21SP3_RS08420 f80df40c6c46b4a96ea1799d7ba31e51 317 SUPERFAMILY SSF159501 28 272 7.5E-52 T 09-03-2017 L21SP3_RS08725 96d08073bfa760ce22c19f8d3e5acdde 362 Gene3D G3DSA:3.90.1150.10 250 309 2.7E-14 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS08725 96d08073bfa760ce22c19f8d3e5acdde 362 SUPERFAMILY SSF53383 15 311 1.77E-68 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS08725 96d08073bfa760ce22c19f8d3e5acdde 362 Pfam PF00155 Aminotransferase class I and II 48 311 1.6E-25 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 L21SP3_RS08725 96d08073bfa760ce22c19f8d3e5acdde 362 Gene3D G3DSA:3.40.640.10 40 249 5.4E-46 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS02130 50d9e751e32db8771d366774bfa50dce 253 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 252 48.343 T 09-03-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 L21SP3_RS02130 50d9e751e32db8771d366774bfa50dce 253 SUPERFAMILY SSF51366 1 252 3.38E-82 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 L21SP3_RS02130 50d9e751e32db8771d366774bfa50dce 253 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 252 8.6E-114 T 09-03-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 L21SP3_RS02130 50d9e751e32db8771d366774bfa50dce 253 Gene3D G3DSA:3.20.20.70 4 253 1.6E-102 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS02130 50d9e751e32db8771d366774bfa50dce 253 Pfam PF00977 Histidine biosynthesis protein 5 236 6.6E-86 T 09-03-2017 IPR006062 Histidine biosynthesis GO:0000105 L21SP3_RS03340 4fe1627b1ffd61ebee6f7b5cd9096276 267 Gene3D G3DSA:3.30.479.10 135 265 1.4E-32 T 09-03-2017 L21SP3_RS03340 4fe1627b1ffd61ebee6f7b5cd9096276 267 SUPERFAMILY SSF55620 135 265 5.45E-32 T 09-03-2017 L21SP3_RS03340 4fe1627b1ffd61ebee6f7b5cd9096276 267 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 140 265 7.7E-25 T 09-03-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 L21SP3_RS02045 ca05360e9dddd90f6227d1111caf85dd 372 Pfam PF02405 Permease MlaE 159 365 1.1E-59 T 09-03-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 L21SP3_RS09140 731264cf9ca7f8ee973717045c9aa55f 339 SUPERFAMILY SSF75005 81 327 2.67E-18 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS09140 731264cf9ca7f8ee973717045c9aa55f 339 Gene3D G3DSA:2.115.10.20 81 301 1.1E-14 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS00320 e87fca93a8b8b1f7987152b787224b0c 491 Gene3D G3DSA:3.20.20.80 55 390 5.7E-21 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS00320 e87fca93a8b8b1f7987152b787224b0c 491 SUPERFAMILY SSF51445 66 390 4.04E-36 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS00320 e87fca93a8b8b1f7987152b787224b0c 491 Pfam PF03662 Glycosyl hydrolase family 79, N-terminal domain 167 267 2.9E-6 T 09-03-2017 IPR005199 Glycoside hydrolase, family 79 GO:0016020|GO:0016798 Reactome: R-HSA-2024096 L21SP3_RS07275 f3260da32156455626e6df2be163e4cf 87 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 87 1.9E-22 T 09-03-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 L21SP3_RS07275 f3260da32156455626e6df2be163e4cf 87 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 17.295 T 09-03-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 L21SP3_RS07275 f3260da32156455626e6df2be163e4cf 87 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 6 85 3.4E-8 T 09-03-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 L21SP3_RS07275 f3260da32156455626e6df2be163e4cf 87 SUPERFAMILY SSF101386 2 87 4.11E-21 T 09-03-2017 L21SP3_RS02775 120f73f2bf5c0ecf3978e796dc730982 396 Gene3D G3DSA:1.20.1250.20 200 382 5.0E-19 T 09-03-2017 L21SP3_RS02775 120f73f2bf5c0ecf3978e796dc730982 396 SUPERFAMILY SSF103473 3 383 4.58E-46 T 09-03-2017 IPR020846 Major facilitator superfamily domain L21SP3_RS02775 120f73f2bf5c0ecf3978e796dc730982 396 Gene3D G3DSA:1.20.1250.20 5 192 5.7E-19 T 09-03-2017 L21SP3_RS02775 120f73f2bf5c0ecf3978e796dc730982 396 Pfam PF07690 Major Facilitator Superfamily 22 229 2.6E-21 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 L21SP3_RS09590 cd5531f873c5daebb7af5af379228d9c 448 Pfam PF02687 FtsX-like permease family 306 435 2.6E-11 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 L21SP3_RS05320 b58499d93daa2a3bbdaef043cabfc2c6 278 Hamap MF_02040 Iron-sulfur cluster carrier protein. 26 274 35.179 T 09-03-2017 IPR019591 Mrp/NBP35 ATP-binding protein L21SP3_RS05320 b58499d93daa2a3bbdaef043cabfc2c6 278 Gene3D G3DSA:3.40.50.300 27 271 4.8E-99 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05320 b58499d93daa2a3bbdaef043cabfc2c6 278 SUPERFAMILY SSF52540 29 258 3.22E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05320 b58499d93daa2a3bbdaef043cabfc2c6 278 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 31 275 1.5E-97 T 09-03-2017 IPR019591 Mrp/NBP35 ATP-binding protein L21SP3_RS05320 b58499d93daa2a3bbdaef043cabfc2c6 278 ProSitePatterns PS01215 Mrp family signature. 139 155 - T 09-03-2017 IPR000808 Mrp, conserved site GO:0005524 L21SP3_RS11200 0f790c52f568071561c281cb295f9e4e 78 Pfam PF05168 HEPN domain 5 58 1.8E-5 T 09-03-2017 IPR007842 HEPN domain L21SP3_RS11200 0f790c52f568071561c281cb295f9e4e 78 SUPERFAMILY SSF81593 4 56 3.26E-6 T 09-03-2017 L21SP3_RS11200 0f790c52f568071561c281cb295f9e4e 78 Gene3D G3DSA:1.20.120.330 3 58 6.3E-7 T 09-03-2017 L21SP3_RS01850 2bceb09d514213f66328e485b3d1c43e 175 Pfam PF00156 Phosphoribosyl transferase domain 52 154 9.5E-12 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 L21SP3_RS01850 2bceb09d514213f66328e485b3d1c43e 175 Gene3D G3DSA:3.40.50.2020 3 171 2.5E-42 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like L21SP3_RS01850 2bceb09d514213f66328e485b3d1c43e 175 SUPERFAMILY SSF53271 8 170 2.36E-38 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like L21SP3_RS01850 2bceb09d514213f66328e485b3d1c43e 175 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 11 171 4.7E-41 T 09-03-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 L21SP3_RS01850 2bceb09d514213f66328e485b3d1c43e 175 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 175 22.471 T 09-03-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 L21SP3_RS10990 5e157b187dd247c00815ed89e9ad2b81 390 Pfam PF00534 Glycosyl transferases group 1 202 364 1.8E-27 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 L21SP3_RS10990 5e157b187dd247c00815ed89e9ad2b81 390 Gene3D G3DSA:3.40.50.2000 181 364 3.4E-25 T 09-03-2017 L21SP3_RS10990 5e157b187dd247c00815ed89e9ad2b81 390 Pfam PF13439 Glycosyltransferase Family 4 12 185 2.4E-21 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 L21SP3_RS10990 5e157b187dd247c00815ed89e9ad2b81 390 SUPERFAMILY SSF53756 3 385 5.5E-75 T 09-03-2017 L21SP3_RS02360 7cf13956092853152ba152a6599a785e 656 Pfam PF01496 V-type ATPase 116kDa subunit family 186 388 2.6E-11 T 09-03-2017 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS02360 7cf13956092853152ba152a6599a785e 656 Pfam PF01496 V-type ATPase 116kDa subunit family 560 643 2.0E-10 T 09-03-2017 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS05895 c9c2a29ce0f88a7c13cda9235ebe21c4 192 Gene3D G3DSA:3.40.920.10 4 191 1.0E-38 T 09-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP3_RS05895 c9c2a29ce0f88a7c13cda9235ebe21c4 192 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 191 1.6E-37 T 09-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 L21SP3_RS05895 c9c2a29ce0f88a7c13cda9235ebe21c4 192 SUPERFAMILY SSF53323 4 192 1.31E-42 T 09-03-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 L21SP3_RS04980 c59dba55189588e1a1b60bdc360998c7 37 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 16 34 2.7E-6 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS04980 c59dba55189588e1a1b60bdc360998c7 37 Pfam PF07589 PEP-CTERM motif 15 32 3.3E-7 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS09120 d07fd622b45ea34a97043888e2f898ac 283 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 263 2.3E-102 T 09-03-2017 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate L21SP3_RS09120 d07fd622b45ea34a97043888e2f898ac 283 SUPERFAMILY SSF52518 12 280 2.33E-69 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS09120 d07fd622b45ea34a97043888e2f898ac 283 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 258 8.9E-23 T 09-03-2017 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal L21SP3_RS09120 d07fd622b45ea34a97043888e2f898ac 283 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 52 194 1.3E-23 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 L21SP3_RS09120 d07fd622b45ea34a97043888e2f898ac 283 Gene3D G3DSA:3.40.50.970 15 278 4.9E-70 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold L21SP3_RS02170 156ada1405f1e67160e94f50f68cb686 225 Pfam PF01081 KDPG and KHG aldolase 13 208 8.7E-35 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 L21SP3_RS02170 156ada1405f1e67160e94f50f68cb686 225 Gene3D G3DSA:3.20.20.70 3 222 1.2E-63 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS02170 156ada1405f1e67160e94f50f68cb686 225 SUPERFAMILY SSF51569 6 217 2.93E-54 T 09-03-2017 L21SP3_RS06975 6c9a904692b42a6b036fe6557dfe4448 902 Pfam PF07581 The GLUG motif 101 125 0.0013 T 09-03-2017 IPR011493 GLUG L21SP3_RS06975 6c9a904692b42a6b036fe6557dfe4448 902 Pfam PF07581 The GLUG motif 737 758 6.3E-4 T 09-03-2017 IPR011493 GLUG L21SP3_RS06975 6c9a904692b42a6b036fe6557dfe4448 902 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 521 569 7.4E-4 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS06975 6c9a904692b42a6b036fe6557dfe4448 902 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 390 445 0.001 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS06975 6c9a904692b42a6b036fe6557dfe4448 902 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 456 514 2.1E-4 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS06975 6c9a904692b42a6b036fe6557dfe4448 902 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 326 375 1.6E-6 T 09-03-2017 IPR013378 Listeria/Bacterioides repeat L21SP3_RS03180 825705f7e9c83caceaf5824241c86fb3 242 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 222 242 0.0014 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS03180 825705f7e9c83caceaf5824241c86fb3 242 Pfam PF07589 PEP-CTERM motif 222 241 2.7E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS07910 953dc2a7f350ece7e4d81367c8108885 456 TIGRFAM TIGR00836 amt: ammonium transporter 42 447 3.0E-135 T 09-03-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 L21SP3_RS07910 953dc2a7f350ece7e4d81367c8108885 456 SUPERFAMILY SSF111352 38 428 4.45E-114 T 09-03-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 L21SP3_RS07910 953dc2a7f350ece7e4d81367c8108885 456 Pfam PF00909 Ammonium Transporter Family 44 447 2.6E-127 T 09-03-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 L21SP3_RS07910 953dc2a7f350ece7e4d81367c8108885 456 ProSitePatterns PS01219 Ammonium transporters signature. 195 220 - T 09-03-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 L21SP3_RS07910 953dc2a7f350ece7e4d81367c8108885 456 Gene3D G3DSA:1.10.3430.10 37 428 2.6E-123 T 09-03-2017 IPR029020 Ammonium/urea transporter L21SP3_RS02800 dc5b6f8e39b406c220c2d3eae7a179d6 297 Pfam PF01256 Carbohydrate kinase 26 289 2.1E-52 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 L21SP3_RS02800 dc5b6f8e39b406c220c2d3eae7a179d6 297 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 8 292 6.4E-64 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 L21SP3_RS02800 dc5b6f8e39b406c220c2d3eae7a179d6 297 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 2 297 22.365 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 L21SP3_RS02800 dc5b6f8e39b406c220c2d3eae7a179d6 297 SUPERFAMILY SSF53613 9 293 7.32E-63 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS02800 dc5b6f8e39b406c220c2d3eae7a179d6 297 Gene3D G3DSA:3.40.1190.20 8 293 9.6E-77 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS06575 d5274102c609f1aeb96055ed0a9f372f 156 Gene3D G3DSA:3.40.930.10 1 153 1.6E-35 T 09-03-2017 IPR002178 PTS EIIA type-2 domain L21SP3_RS06575 d5274102c609f1aeb96055ed0a9f372f 156 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 9 150 7.8E-27 T 09-03-2017 IPR002178 PTS EIIA type-2 domain L21SP3_RS06575 d5274102c609f1aeb96055ed0a9f372f 156 SUPERFAMILY SSF55804 1 150 6.28E-29 T 09-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 L21SP3_RS01305 d9bd991e7f309d574e6bf6c1bcbf70d3 178 Gene3D G3DSA:3.40.109.10 1 176 2.2E-43 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 L21SP3_RS01305 d9bd991e7f309d574e6bf6c1bcbf70d3 178 Pfam PF00881 Nitroreductase family 67 153 1.7E-12 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 L21SP3_RS01305 d9bd991e7f309d574e6bf6c1bcbf70d3 178 Pfam PF00881 Nitroreductase family 8 65 2.2E-12 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 L21SP3_RS01305 d9bd991e7f309d574e6bf6c1bcbf70d3 178 SUPERFAMILY SSF55469 1 176 7.98E-44 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 L21SP3_RS04650 9268f73fc512fcb3ae3be74e88d76fe7 181 Pfam PF04350 Pilus assembly protein, PilO 46 167 1.2E-4 T 09-03-2017 IPR007445 Pilus assembly protein, PilO L21SP3_RS04650 9268f73fc512fcb3ae3be74e88d76fe7 181 Gene3D G3DSA:3.30.70.60 83 169 1.5E-7 T 09-03-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 L21SP3_RS06155 4924421fb9d6d5625a7266b8abc33560 109 SUPERFAMILY SSF50104 4 96 2.36E-27 T 09-03-2017 IPR008991 Translation protein SH3-like domain L21SP3_RS06155 4924421fb9d6d5625a7266b8abc33560 109 SMART SM00739 4 31 3.8E-4 T 09-03-2017 IPR005824 KOW L21SP3_RS06155 4924421fb9d6d5625a7266b8abc33560 109 Pfam PF00467 KOW motif 7 37 1.3E-5 T 09-03-2017 IPR005824 KOW L21SP3_RS06155 4924421fb9d6d5625a7266b8abc33560 109 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 94 1.5E-28 T 09-03-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06155 4924421fb9d6d5625a7266b8abc33560 109 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 106 18.96 T 09-03-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06155 4924421fb9d6d5625a7266b8abc33560 109 Gene3D G3DSA:2.30.30.30 4 92 1.1E-20 T 09-03-2017 IPR014722 Ribosomal protein L2 domain 2 L21SP3_RS06155 4924421fb9d6d5625a7266b8abc33560 109 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 39 95 1.9E-20 T 09-03-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS11480 81a7334d14fa5450fae214cdb21307d9 158 PRINTS PR00394 RHS protein signature 52 71 1.1E-6 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11480 81a7334d14fa5450fae214cdb21307d9 158 PRINTS PR00394 RHS protein signature 29 49 1.1E-6 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11480 81a7334d14fa5450fae214cdb21307d9 158 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 12 85 9.7E-26 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 L21SP3_RS08160 6b98741420de375ab5a52fa7282d7357 90 Pfam PF13240 zinc-ribbon domain 3 22 1.8E-7 T 09-03-2017 IPR026870 Zinc-ribbon domain L21SP3_RS06825 c01cafec81b908ca61061ec653d35b97 229 SMART SM00382 45 226 1.6E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS06825 c01cafec81b908ca61061ec653d35b97 229 SUPERFAMILY SSF52540 18 227 4.51E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS06825 c01cafec81b908ca61061ec653d35b97 229 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS06825 c01cafec81b908ca61061ec653d35b97 229 Pfam PF00005 ABC transporter 36 182 4.6E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS06825 c01cafec81b908ca61061ec653d35b97 229 Gene3D G3DSA:3.40.50.300 19 227 9.7E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04290 5c3e878a9cdddcc6f5a78ca158dc2180 330 Pfam PF06144 DNA polymerase III, delta subunit 14 180 1.3E-17 T 09-03-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 L21SP3_RS04290 5c3e878a9cdddcc6f5a78ca158dc2180 330 Gene3D G3DSA:1.10.8.60 150 222 9.9E-10 T 09-03-2017 L21SP3_RS04290 5c3e878a9cdddcc6f5a78ca158dc2180 330 SUPERFAMILY SSF52540 6 199 4.32E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS04290 5c3e878a9cdddcc6f5a78ca158dc2180 330 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 10 322 1.9E-47 T 09-03-2017 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 L21SP3_RS04290 5c3e878a9cdddcc6f5a78ca158dc2180 330 SUPERFAMILY SSF48019 204 324 2.21E-12 T 09-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 L21SP3_RS04290 5c3e878a9cdddcc6f5a78ca158dc2180 330 Gene3D G3DSA:3.40.50.300 3 121 4.8E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02050 fefa6f40ecbf264353f2669e0ab7ad33 255 Pfam PF00005 ABC transporter 23 172 1.1E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS02050 fefa6f40ecbf264353f2669e0ab7ad33 255 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 L21SP3_RS02050 fefa6f40ecbf264353f2669e0ab7ad33 255 SMART SM00382 32 221 6.5E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS02050 fefa6f40ecbf264353f2669e0ab7ad33 255 Gene3D G3DSA:3.40.50.300 6 248 7.5E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02050 fefa6f40ecbf264353f2669e0ab7ad33 255 SUPERFAMILY SSF52540 9 245 1.01E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02470 e1905138eb8e68e4871cbbc3cd1f6614 730 Pfam PF13402 Peptidase M60, enhancin and enhancin-like 343 703 4.7E-97 T 09-03-2017 IPR031161 Peptidase family M60 domain L21SP3_RS02470 e1905138eb8e68e4871cbbc3cd1f6614 730 SMART SM01276 358 653 4.5E-86 T 09-03-2017 IPR031161 Peptidase family M60 domain L21SP3_RS05125 4287d81b59e6dbe63c233e1989b86af6 288 Pfam PF02585 GlcNAc-PI de-N-acetylase 42 176 4.5E-21 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 L21SP3_RS05125 4287d81b59e6dbe63c233e1989b86af6 288 SUPERFAMILY SSF102588 39 276 4.84E-28 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 L21SP3_RS05125 4287d81b59e6dbe63c233e1989b86af6 288 Gene3D G3DSA:3.40.50.10320 38 262 1.0E-28 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 L21SP3_RS04095 4b80502e943fd4b6cedae3b4ae9f2818 516 Pfam PF07583 Protein of unknown function (DUF1549) 33 155 1.8E-30 T 09-03-2017 IPR011444 Domain of unknown function DUF1549 L21SP3_RS04095 4b80502e943fd4b6cedae3b4ae9f2818 516 Pfam PF07587 Protein of unknown function (DUF1553) 252 487 7.9E-39 T 09-03-2017 IPR022655 Domain of unknown function DUF1553 L21SP3_RS01110 2601b29ed46a9b2e0e566f1789e4461f 194 TIGRFAM TIGR02646 TIGR02646: TIGR02646 family protein 24 154 1.9E-25 T 09-03-2017 IPR013467 Conserved hypothetical protein CHP02646 L21SP3_RS07755 8727ec8a7d48a708e7c373699ba54f1e 115 Pfam PF05258 Protein of unknown function (DUF721) 28 114 2.9E-12 T 09-03-2017 IPR007922 Protein of unknown function DUF721/UPF0232 L21SP3_RS11460 bfaec9d4f3566b3708bf90acd3a88b50 308 PRINTS PR00394 RHS protein signature 99 119 3.0E-7 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11460 bfaec9d4f3566b3708bf90acd3a88b50 308 PRINTS PR00394 RHS protein signature 122 141 3.0E-7 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11460 bfaec9d4f3566b3708bf90acd3a88b50 308 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 71 154 1.2E-25 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 L21SP3_RS09375 61d6539de33a154f878571edb537f69a 426 Pfam PF01609 Transposase DDE domain 279 416 1.8E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS09375 61d6539de33a154f878571edb537f69a 426 Pfam PF05598 Transposase domain (DUF772) 55 129 1.6E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS09290 bcf94eafc9470a03521ade7509d8c827 598 SUPERFAMILY SSF51905 519 571 1.56E-17 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09290 bcf94eafc9470a03521ade7509d8c827 598 SUPERFAMILY SSF51905 408 425 1.56E-17 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09290 bcf94eafc9470a03521ade7509d8c827 598 SUPERFAMILY SSF51905 187 371 1.56E-17 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09290 bcf94eafc9470a03521ade7509d8c827 598 Gene3D G3DSA:3.50.50.60 189 365 4.7E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09290 bcf94eafc9470a03521ade7509d8c827 598 Gene3D G3DSA:3.50.50.60 521 593 4.7E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS09290 bcf94eafc9470a03521ade7509d8c827 598 Pfam PF12831 FAD dependent oxidoreductase 194 593 1.8E-67 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 L21SP3_RS02175 787790d502bebd68ad7a5fd99a0698fa 366 SUPERFAMILY SSF53613 13 357 2.34E-58 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS02175 787790d502bebd68ad7a5fd99a0698fa 366 Gene3D G3DSA:3.40.1190.20 9 363 9.9E-68 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS02175 787790d502bebd68ad7a5fd99a0698fa 366 Pfam PF00294 pfkB family carbohydrate kinase 159 347 3.3E-20 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB L21SP3_RS02480 1a5881d2b18c8bb9594b9cc1909c1295 276 Pfam PF09674 Protein of unknown function (DUF2400) 27 254 5.9E-74 T 09-03-2017 IPR014127 Conserved hypothetical protein CHP02757 L21SP3_RS02480 1a5881d2b18c8bb9594b9cc1909c1295 276 TIGRFAM TIGR02757 TIGR02757: TIGR02757 family protein 23 254 2.6E-64 T 09-03-2017 IPR014127 Conserved hypothetical protein CHP02757 L21SP3_RS02480 1a5881d2b18c8bb9594b9cc1909c1295 276 Gene3D G3DSA:1.10.1670.10 197 275 1.4E-4 T 09-03-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 L21SP3_RS02480 1a5881d2b18c8bb9594b9cc1909c1295 276 SUPERFAMILY SSF48150 201 275 2.36E-7 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 L21SP3_RS09320 29293da494b2f6c3b8863c5d34b5ec9c 561 Pfam PF00474 Sodium:solute symporter family 14 405 1.1E-33 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS07930 65fd4583ad546d8d2eb5a0bda0ee8b4b 301 SMART SM00240 21 72 3.1E-12 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 L21SP3_RS07930 65fd4583ad546d8d2eb5a0bda0ee8b4b 301 SUPERFAMILY SSF49879 3 95 1.19E-22 T 09-03-2017 IPR008984 SMAD/FHA domain GO:0005515 L21SP3_RS07930 65fd4583ad546d8d2eb5a0bda0ee8b4b 301 Gene3D G3DSA:2.60.200.20 3 101 3.0E-22 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 L21SP3_RS07930 65fd4583ad546d8d2eb5a0bda0ee8b4b 301 Pfam PF00498 FHA domain 23 85 1.1E-15 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 L21SP3_RS02455 b535d11359cf3170466e3d38a5299d91 365 Gene3D G3DSA:2.115.10.20 68 355 3.4E-14 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS02455 b535d11359cf3170466e3d38a5299d91 365 SUPERFAMILY SSF75005 66 343 8.01E-15 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS02700 2d7e6ae30fc415373b61ec986fdc6101 144 Gene3D G3DSA:3.30.70.260 6 53 5.9E-8 T 09-03-2017 L21SP3_RS02700 2d7e6ae30fc415373b61ec986fdc6101 144 Gene3D G3DSA:3.30.70.260 72 130 3.5E-4 T 09-03-2017 L21SP3_RS02700 2d7e6ae30fc415373b61ec986fdc6101 144 SUPERFAMILY SSF55021 1 65 2.29E-13 T 09-03-2017 L21SP3_RS02700 2d7e6ae30fc415373b61ec986fdc6101 144 SUPERFAMILY SSF55021 73 130 1.72E-7 T 09-03-2017 L21SP3_RS06045 a8082fa5930667d4cbcb02109c6fa037 272 Gene3D G3DSA:3.40.225.10 2 263 8.3E-76 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal L21SP3_RS06045 a8082fa5930667d4cbcb02109c6fa037 272 SUPERFAMILY SSF53639 3 259 2.55E-54 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal L21SP3_RS06045 a8082fa5930667d4cbcb02109c6fa037 272 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 231 9.0E-31 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal L21SP3_RS06045 a8082fa5930667d4cbcb02109c6fa037 272 SMART SM01007 8 233 8.4E-26 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal L21SP3_RS10250 88861da45241b5e0eedaf89d7d72e143 131 SMART SM00345 17 76 3.0E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP3_RS10250 88861da45241b5e0eedaf89d7d72e143 131 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.0E-18 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 L21SP3_RS10250 88861da45241b5e0eedaf89d7d72e143 131 SUPERFAMILY SSF46785 6 86 1.11E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS10250 88861da45241b5e0eedaf89d7d72e143 131 Gene3D G3DSA:1.10.10.10 3 77 1.6E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS08075 0a6f706c428079c4168d818342aa9218 494 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 62 226 4.1E-18 T 09-03-2017 L21SP3_RS03005 592fe6b08d2e9573b81ce312a17229ad 141 SUPERFAMILY SSF54928 42 134 2.82E-28 T 09-03-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 L21SP3_RS03005 592fe6b08d2e9573b81ce312a17229ad 141 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 54 122 1.4E-19 T 09-03-2017 IPR000504 RNA recognition motif domain GO:0003676 L21SP3_RS03005 592fe6b08d2e9573b81ce312a17229ad 141 Gene3D G3DSA:3.30.70.330 26 135 3.8E-30 T 09-03-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 L21SP3_RS03005 592fe6b08d2e9573b81ce312a17229ad 141 SMART SM00360 52 125 1.5E-24 T 09-03-2017 IPR000504 RNA recognition motif domain GO:0003676 L21SP3_RS05840 10dda42f12c1fb30a8468f2eb1fc9cee 288 Pfam PF01148 Cytidylyltransferase family 4 286 6.9E-54 T 09-03-2017 L21SP3_RS02380 a75c86d91cc8c51339b3466e5d6e46a0 131 Gene3D G3DSA:3.40.50.10580 28 106 5.0E-11 T 09-03-2017 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS02380 a75c86d91cc8c51339b3466e5d6e46a0 131 Pfam PF01990 ATP synthase (F/14-kDa) subunit 31 115 7.9E-13 T 09-03-2017 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS02380 a75c86d91cc8c51339b3466e5d6e46a0 131 SUPERFAMILY SSF159468 31 128 9.42E-15 T 09-03-2017 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS07980 ec077e12256c7a04a380464c9c9b2fcf 374 Pfam PF07581 The GLUG motif 270 293 0.002 T 09-03-2017 IPR011493 GLUG L21SP3_RS07980 ec077e12256c7a04a380464c9c9b2fcf 374 Pfam PF07581 The GLUG motif 297 321 3.2E-4 T 09-03-2017 IPR011493 GLUG L21SP3_RS06130 c6b71f99213c66c7b60209749e723f71 121 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 5 121 28.168 T 09-03-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS06130 c6b71f99213c66c7b60209749e723f71 121 SUPERFAMILY SSF53137 7 119 1.79E-49 T 09-03-2017 L21SP3_RS06130 c6b71f99213c66c7b60209749e723f71 121 Gene3D G3DSA:3.30.420.100 25 121 1.3E-37 T 09-03-2017 L21SP3_RS06130 c6b71f99213c66c7b60209749e723f71 121 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 7 121 3.1E-43 T 09-03-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS06130 c6b71f99213c66c7b60209749e723f71 121 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 121 1.2E-39 T 09-03-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 L21SP3_RS02370 3e2288a9ec56edf3a57262dc55fec042 193 SUPERFAMILY SSF160527 81 191 9.42E-11 T 09-03-2017 L21SP3_RS02370 3e2288a9ec56edf3a57262dc55fec042 193 Pfam PF01991 ATP synthase (E/31 kDa) subunit 10 191 8.1E-8 T 09-03-2017 IPR002842 ATPase, V1/A1 complex, subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 L21SP3_RS04745 0523a47c6701b5327a8d2c635225c25d 398 Pfam PF02719 Polysaccharide biosynthesis protein 37 339 5.7E-35 T 09-03-2017 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain L21SP3_RS04745 0523a47c6701b5327a8d2c635225c25d 398 SUPERFAMILY SSF51735 34 325 2.58E-19 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS04745 0523a47c6701b5327a8d2c635225c25d 398 Gene3D G3DSA:3.40.50.720 33 247 8.6E-20 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS02365 f834f9532b130f7513acb9f8e68e7802 172 Pfam PF00137 ATP synthase subunit C 16 74 2.4E-10 T 09-03-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 L21SP3_RS02365 f834f9532b130f7513acb9f8e68e7802 172 Pfam PF00137 ATP synthase subunit C 100 160 1.3E-12 T 09-03-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 L21SP3_RS02365 f834f9532b130f7513acb9f8e68e7802 172 SUPERFAMILY SSF81333 92 161 1.06E-10 T 09-03-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 L21SP3_RS02365 f834f9532b130f7513acb9f8e68e7802 172 Gene3D G3DSA:1.20.120.610 10 162 8.1E-30 T 09-03-2017 L21SP3_RS02365 f834f9532b130f7513acb9f8e68e7802 172 SUPERFAMILY SSF81333 11 76 2.75E-9 T 09-03-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 L21SP3_RS00160 5650fc9f88914b8e11d1cb94c2594154 173 SUPERFAMILY SSF52833 17 170 1.49E-48 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS00160 5650fc9f88914b8e11d1cb94c2594154 173 Gene3D G3DSA:3.40.30.10 87 169 3.3E-11 T 09-03-2017 IPR012336 Thioredoxin-like fold L21SP3_RS00160 5650fc9f88914b8e11d1cb94c2594154 173 PIRSF PIRSF000216 4 173 5.4E-52 T 09-03-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS00160 5650fc9f88914b8e11d1cb94c2594154 173 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 24 167 7.9E-48 T 09-03-2017 L21SP3_RS04655 e42c454405b8c596b219608f5304d3a6 415 Pfam PF05137 Fimbrial assembly protein (PilN) 333 409 2.3E-6 T 09-03-2017 IPR007813 Fimbrial assembly PilN L21SP3_RS04655 e42c454405b8c596b219608f5304d3a6 415 SUPERFAMILY SSF53067 57 145 7.12E-5 T 09-03-2017 L21SP3_RS04475 264c2b54f8d4dca6f04692d258625f9f 753 SUPERFAMILY SSF49899 490 705 1.49E-23 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04475 264c2b54f8d4dca6f04692d258625f9f 753 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 562 700 6.4E-16 T 09-03-2017 L21SP3_RS04475 264c2b54f8d4dca6f04692d258625f9f 753 Gene3D G3DSA:2.60.120.200 493 706 1.1E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS04475 264c2b54f8d4dca6f04692d258625f9f 753 SMART SM00560 562 698 0.0081 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS01925 817b5f1391211b93ad89031c401808ec 540 Gene3D G3DSA:2.60.120.200 276 489 7.8E-34 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS01925 817b5f1391211b93ad89031c401808ec 540 SMART SM00560 342 478 9.3E-4 T 09-03-2017 IPR006558 LamG-like jellyroll fold L21SP3_RS01925 817b5f1391211b93ad89031c401808ec 540 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 338 482 2.6E-23 T 09-03-2017 L21SP3_RS01925 817b5f1391211b93ad89031c401808ec 540 SUPERFAMILY SSF49899 276 489 1.21E-32 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS08935 d74c2c6c83270445cc3ba3a8ae80af9c 406 Pfam PF14294 Domain of unknown function (DUF4372) 7 73 7.0E-15 T 09-03-2017 IPR025399 Domain of unknown function DUF4372 L21SP3_RS08935 d74c2c6c83270445cc3ba3a8ae80af9c 406 SUPERFAMILY SSF53098 128 370 1.67E-24 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS08935 d74c2c6c83270445cc3ba3a8ae80af9c 406 Pfam PF01609 Transposase DDE domain 131 346 9.7E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS08935 d74c2c6c83270445cc3ba3a8ae80af9c 406 Gene3D G3DSA:3.90.350.10 255 322 2.9E-4 T 09-03-2017 IPR014736 Transposase, Tn5-like, core L21SP3_RS11680 e6b35b3ff84ecdaecf9f6bc9d77f1347 59 TIGRFAM TIGR04258 4helix_suffix: four helix bundle suffix domain 12 57 1.2E-19 T 09-03-2017 IPR026354 Four helix bundle suffix domain L21SP3_RS10865 f0605195b7d91447c50d894dcb64caf1 308 SUPERFAMILY SSF53613 6 295 2.18E-60 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS10865 f0605195b7d91447c50d894dcb64caf1 308 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 28 52 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 L21SP3_RS10865 f0605195b7d91447c50d894dcb64caf1 308 Gene3D G3DSA:3.40.1190.20 6 292 9.0E-62 T 09-03-2017 IPR029056 Ribokinase-like L21SP3_RS10865 f0605195b7d91447c50d894dcb64caf1 308 Pfam PF00294 pfkB family carbohydrate kinase 26 292 1.8E-42 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB L21SP3_RS10865 f0605195b7d91447c50d894dcb64caf1 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 244 257 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 L21SP3_RS07050 cfe0e701127240eb6c727ea470b8eaab 472 Gene3D G3DSA:3.40.50.300 234 334 5.4E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS07050 cfe0e701127240eb6c727ea470b8eaab 472 Pfam PF00158 Sigma-54 interaction domain 229 315 3.6E-9 T 09-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 L21SP3_RS07050 cfe0e701127240eb6c727ea470b8eaab 472 SUPERFAMILY SSF52540 227 399 1.42E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS11405 91c4dacdc619d6ec2d12a81dfe63f036 1664 Pfam PF05593 RHS Repeat 1053 1088 9.7E-6 T 09-03-2017 IPR031325 RHS repeat L21SP3_RS11405 91c4dacdc619d6ec2d12a81dfe63f036 1664 Pfam PF05593 RHS Repeat 823 858 1.9E-7 T 09-03-2017 IPR031325 RHS repeat L21SP3_RS11405 91c4dacdc619d6ec2d12a81dfe63f036 1664 Pfam PF05593 RHS Repeat 681 712 2.2E-5 T 09-03-2017 IPR031325 RHS repeat L21SP3_RS11405 91c4dacdc619d6ec2d12a81dfe63f036 1664 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 823 863 7.8E-6 T 09-03-2017 IPR006530 YD repeat L21SP3_RS11405 91c4dacdc619d6ec2d12a81dfe63f036 1664 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1074 1110 2.3E-6 T 09-03-2017 IPR006530 YD repeat L21SP3_RS11405 91c4dacdc619d6ec2d12a81dfe63f036 1664 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1447 1531 2.0E-24 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 L21SP3_RS06930 8ec6f29a29f0668b99200882e4f623cf 119 PRINTS PR01217 Proline rich extensin signature 10 31 3.1E-10 T 09-03-2017 L21SP3_RS06930 8ec6f29a29f0668b99200882e4f623cf 119 PRINTS PR01217 Proline rich extensin signature 72 97 3.1E-10 T 09-03-2017 L21SP3_RS06930 8ec6f29a29f0668b99200882e4f623cf 119 PRINTS PR01217 Proline rich extensin signature 32 48 3.1E-10 T 09-03-2017 L21SP3_RS06930 8ec6f29a29f0668b99200882e4f623cf 119 PRINTS PR01217 Proline rich extensin signature 50 67 3.1E-10 T 09-03-2017 L21SP3_RS06950 29652b2fd9f62f39d3db622b0e96aa9e 151 Pfam PF07589 PEP-CTERM motif 129 148 2.2E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS06950 29652b2fd9f62f39d3db622b0e96aa9e 151 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 129 150 2.0E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS09390 9eb5b748f975c5717a067cde048ecb2e 237 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 19 197 1.5E-38 T 09-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 L21SP3_RS09390 9eb5b748f975c5717a067cde048ecb2e 237 SUPERFAMILY SSF53335 7 235 1.44E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS09390 9eb5b748f975c5717a067cde048ecb2e 237 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 6 198 23.579 T 09-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 L21SP3_RS09390 9eb5b748f975c5717a067cde048ecb2e 237 Pfam PF02527 rRNA small subunit methyltransferase G 14 188 1.9E-40 T 09-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 L21SP3_RS09390 9eb5b748f975c5717a067cde048ecb2e 237 Gene3D G3DSA:3.40.50.150 4 235 5.1E-56 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS08025 a6a58e9ec2b12d0e95fdd2767f4e7367 319 Pfam PF00149 Calcineurin-like phosphoesterase 45 267 6.8E-16 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 L21SP3_RS08025 a6a58e9ec2b12d0e95fdd2767f4e7367 319 SUPERFAMILY SSF56300 44 312 6.96E-45 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS08025 a6a58e9ec2b12d0e95fdd2767f4e7367 319 Gene3D G3DSA:3.60.21.10 41 282 1.3E-37 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS03045 bbee5e8822d20dfd9fce92a304c998fa 531 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 313 351 7.6E-8 T 09-03-2017 IPR001434 Domain of unknown function DUF11 L21SP3_RS03045 bbee5e8822d20dfd9fce92a304c998fa 531 Pfam PF01345 Domain of unknown function DUF11 191 241 1.6E-6 T 09-03-2017 IPR001434 Domain of unknown function DUF11 L21SP3_RS03045 bbee5e8822d20dfd9fce92a304c998fa 531 Pfam PF01345 Domain of unknown function DUF11 311 351 2.3E-7 T 09-03-2017 IPR001434 Domain of unknown function DUF11 L21SP3_RS00365 3310ec6c4bdb2a88dd8c5a4ef656da5c 320 Pfam PF04616 Glycosyl hydrolases family 43 27 305 4.2E-46 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS00365 3310ec6c4bdb2a88dd8c5a4ef656da5c 320 Gene3D G3DSA:2.115.10.20 17 306 1.6E-75 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS00365 3310ec6c4bdb2a88dd8c5a4ef656da5c 320 SUPERFAMILY SSF75005 12 306 1.43E-69 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS11445 a5929757d5860e88b564bba948785185 233 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 9 72 3.0E-24 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 L21SP3_RS11445 a5929757d5860e88b564bba948785185 233 PRINTS PR00394 RHS protein signature 39 58 1.1E-6 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11445 a5929757d5860e88b564bba948785185 233 PRINTS PR00394 RHS protein signature 16 36 1.1E-6 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11220 ad171d7cf27f5ceaee6bccec0ea0dfe1 513 Pfam PF00884 Sulfatase 34 371 2.0E-64 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS11220 ad171d7cf27f5ceaee6bccec0ea0dfe1 513 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 24 3.0E-5 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal L21SP3_RS11220 ad171d7cf27f5ceaee6bccec0ea0dfe1 513 Gene3D G3DSA:3.40.720.10 34 391 1.1E-96 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS11220 ad171d7cf27f5ceaee6bccec0ea0dfe1 513 Gene3D G3DSA:3.30.1120.10 412 496 4.9E-14 T 09-03-2017 L21SP3_RS11220 ad171d7cf27f5ceaee6bccec0ea0dfe1 513 SUPERFAMILY SSF53649 33 483 9.29E-107 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS11220 ad171d7cf27f5ceaee6bccec0ea0dfe1 513 ProSitePatterns PS00149 Sulfatases signature 2. 122 132 - T 09-03-2017 IPR024607 Sulfatase, conserved site L21SP3_RS00505 bb21dcd28b47d6d563eded8f6181622b 508 Gene3D G3DSA:3.10.560.10 349 373 1.8E-4 T 09-03-2017 L21SP3_RS00505 bb21dcd28b47d6d563eded8f6181622b 508 Pfam PF10531 SLBB domain 388 431 5.1E-7 T 09-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS00505 bb21dcd28b47d6d563eded8f6181622b 508 Pfam PF02563 Polysaccharide biosynthesis/export protein 74 150 7.4E-14 T 09-03-2017 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 L21SP3_RS00505 bb21dcd28b47d6d563eded8f6181622b 508 Gene3D G3DSA:3.30.1950.10 80 146 1.4E-10 T 09-03-2017 L21SP3_RS00505 bb21dcd28b47d6d563eded8f6181622b 508 Gene3D G3DSA:3.10.560.10 147 223 2.7E-4 T 09-03-2017 L21SP3_RS00505 bb21dcd28b47d6d563eded8f6181622b 508 Gene3D G3DSA:3.10.560.10 374 466 1.1E-15 T 09-03-2017 L21SP3_RS05790 dcef32b76fdc8cff8c92f67223ad33f0 168 Gene3D G3DSA:4.10.860.10 139 168 7.0E-4 T 09-03-2017 IPR001943 UVR domain GO:0005515 L21SP3_RS05790 dcef32b76fdc8cff8c92f67223ad33f0 168 PIRSF PIRSF015034 1 168 2.4E-36 T 09-03-2017 IPR025542 YacH protein L21SP3_RS05790 dcef32b76fdc8cff8c92f67223ad33f0 168 Pfam PF02151 UvrB/uvrC motif 141 168 4.8E-6 T 09-03-2017 IPR001943 UVR domain GO:0005515 L21SP3_RS05790 dcef32b76fdc8cff8c92f67223ad33f0 168 Gene3D G3DSA:3.30.40.10 72 86 8.5E-4 T 09-03-2017 IPR013083 Zinc finger, RING/FYVE/PHD-type L21SP3_RS05790 dcef32b76fdc8cff8c92f67223ad33f0 168 Gene3D G3DSA:3.30.40.10 27 37 8.5E-4 T 09-03-2017 IPR013083 Zinc finger, RING/FYVE/PHD-type L21SP3_RS02895 60a00dc85431d0afdfc41f06b20610bb 407 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 106 406 33.37 T 09-03-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 L21SP3_RS02895 60a00dc85431d0afdfc41f06b20610bb 407 Gene3D G3DSA:1.10.40.50 342 405 2.8E-25 T 09-03-2017 L21SP3_RS02895 60a00dc85431d0afdfc41f06b20610bb 407 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 144 400 2.6E-69 T 09-03-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 L21SP3_RS02895 60a00dc85431d0afdfc41f06b20610bb 407 SUPERFAMILY SSF52540 181 402 4.91E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02895 60a00dc85431d0afdfc41f06b20610bb 407 Gene3D G3DSA:3.40.50.300 182 341 3.1E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS02895 60a00dc85431d0afdfc41f06b20610bb 407 Pfam PF03193 Protein of unknown function, DUF258 164 342 1.6E-51 T 09-03-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 L21SP3_RS09525 351f371f2684e7879e249e2875f836ee 315 Gene3D G3DSA:3.60.21.10 95 260 1.5E-17 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS09525 351f371f2684e7879e249e2875f836ee 315 SUPERFAMILY SSF56300 94 312 4.62E-22 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like L21SP3_RS09525 351f371f2684e7879e249e2875f836ee 315 Pfam PF00149 Calcineurin-like phosphoesterase 96 213 1.8E-4 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 L21SP3_RS02105 73183844de475042ff0781051ce144d1 768 Gene3D G3DSA:3.10.20.310 95 171 1.4E-5 T 09-03-2017 L21SP3_RS02105 73183844de475042ff0781051ce144d1 768 Pfam PF07244 Surface antigen variable number repeat 174 258 2.0E-10 T 09-03-2017 IPR010827 Surface antigen variable number GO:0019867 L21SP3_RS02105 73183844de475042ff0781051ce144d1 768 Pfam PF07244 Surface antigen variable number repeat 98 171 1.5E-9 T 09-03-2017 IPR010827 Surface antigen variable number GO:0019867 L21SP3_RS02105 73183844de475042ff0781051ce144d1 768 Pfam PF07244 Surface antigen variable number repeat 342 422 5.6E-5 T 09-03-2017 IPR010827 Surface antigen variable number GO:0019867 L21SP3_RS02105 73183844de475042ff0781051ce144d1 768 Pfam PF07244 Surface antigen variable number repeat 267 338 2.2E-12 T 09-03-2017 IPR010827 Surface antigen variable number GO:0019867 L21SP3_RS02105 73183844de475042ff0781051ce144d1 768 Gene3D G3DSA:2.40.160.50 519 758 1.6E-13 T 09-03-2017 L21SP3_RS02105 73183844de475042ff0781051ce144d1 768 Pfam PF01103 Surface antigen 468 768 2.9E-35 T 09-03-2017 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 L21SP3_RS02105 73183844de475042ff0781051ce144d1 768 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 26 768 1.8E-104 T 09-03-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 L21SP3_RS04750 cd997802ef58dab510aea3fb54a17e26 123 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 7 120 1.3E-39 T 09-03-2017 IPR026350 GxxExxY protein L21SP3_RS04750 cd997802ef58dab510aea3fb54a17e26 123 Pfam PF13366 PD-(D/E)XK nuclease superfamily 5 118 6.8E-39 T 09-03-2017 IPR026350 GxxExxY protein L21SP3_RS00710 d6b4756d0cb4f957a137653b6d3e5b60 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 238 4.2E-83 T 09-03-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 L21SP3_RS00710 d6b4756d0cb4f957a137653b6d3e5b60 240 PIRSF PIRSF005650 1 240 3.8E-79 T 09-03-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 L21SP3_RS00710 d6b4756d0cb4f957a137653b6d3e5b60 240 SUPERFAMILY SSF53633 5 238 8.64E-64 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase L21SP3_RS00710 d6b4756d0cb4f957a137653b6d3e5b60 240 Pfam PF00696 Amino acid kinase family 7 218 6.1E-34 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase L21SP3_RS00710 d6b4756d0cb4f957a137653b6d3e5b60 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 239 37.317 T 09-03-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 L21SP3_RS00710 d6b4756d0cb4f957a137653b6d3e5b60 240 Gene3D G3DSA:3.40.1160.10 4 239 7.0E-76 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase L21SP3_RS02930 bec7a7fe7adfb6d944be0fd17f39c5b3 197 Gene3D G3DSA:3.40.50.10610 15 190 5.5E-15 T 09-03-2017 IPR005586 ABC-type transport auxiliary lipoprotein component L21SP3_RS02930 bec7a7fe7adfb6d944be0fd17f39c5b3 197 SUPERFAMILY SSF159594 25 188 3.14E-15 T 09-03-2017 L21SP3_RS10550 78101fe58edb93fb792de9b3a2c3e0af 502 Pfam PF16401 Domain of unknown function (DUF5009) 21 296 9.2E-73 T 09-03-2017 IPR032176 Domain of unknown function DUF5009 L21SP3_RS05470 067b15a13a16653a6ceebbec42ed5df8 318 Gene3D G3DSA:2.60.120.200 137 293 1.7E-12 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05470 067b15a13a16653a6ceebbec42ed5df8 318 SUPERFAMILY SSF49899 140 293 3.48E-12 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS05470 067b15a13a16653a6ceebbec42ed5df8 318 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 296 317 7.1E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS05470 067b15a13a16653a6ceebbec42ed5df8 318 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 140 292 1.4E-11 T 09-03-2017 L21SP3_RS02200 fe0b4042c907ed960b5cbb8f8c00ec17 302 Pfam PF00483 Nucleotidyl transferase 6 170 6.6E-6 T 09-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 L21SP3_RS02200 fe0b4042c907ed960b5cbb8f8c00ec17 302 Gene3D G3DSA:3.90.550.10 5 289 1.9E-20 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS02200 fe0b4042c907ed960b5cbb8f8c00ec17 302 SUPERFAMILY SSF53448 6 286 6.34E-21 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS02850 319947a8c6ed1c8a11c71edc48c784bd 416 Pfam PF09861 Domain of unknown function (DUF2088) 29 179 6.6E-12 T 09-03-2017 IPR018657 Domain of unknown function DUF2088 L21SP3_RS04200 0be66a2b4492586bf096c7985bc6cdf0 199 SUPERFAMILY SSF53335 1 188 3.95E-42 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS04200 0be66a2b4492586bf096c7985bc6cdf0 199 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 189 4.8E-40 T 09-03-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP3_RS04200 0be66a2b4492586bf096c7985bc6cdf0 199 Pfam PF03602 Conserved hypothetical protein 95 1 188 5.7E-45 T 09-03-2017 L21SP3_RS04200 0be66a2b4492586bf096c7985bc6cdf0 199 Gene3D G3DSA:3.40.50.150 1 192 8.7E-51 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase L21SP3_RS04200 0be66a2b4492586bf096c7985bc6cdf0 199 PIRSF PIRSF004553 1 192 4.2E-46 T 09-03-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 L21SP3_RS04200 0be66a2b4492586bf096c7985bc6cdf0 199 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 120 126 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 L21SP3_RS03960 38ca307577ff2213586c9492cc8ff739 203 Pfam PF04205 FMN-binding domain 99 186 4.2E-13 T 09-03-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 L21SP3_RS03960 38ca307577ff2213586c9492cc8ff739 203 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 7 193 19.982 T 09-03-2017 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 L21SP3_RS03960 38ca307577ff2213586c9492cc8ff739 203 SMART SM00900 99 191 2.3E-12 T 09-03-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 L21SP3_RS03960 38ca307577ff2213586c9492cc8ff739 203 PIRSF PIRSF006091 1 200 1.7E-30 T 09-03-2017 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 L21SP3_RS00270 93b46ecf8d659eb41d063c790e8f552e 262 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 239 260 5.6E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS10650 7240c7358b12c46b117cb25cbb94684b 462 Pfam PF00884 Sulfatase 28 358 1.3E-72 T 09-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 L21SP3_RS10650 7240c7358b12c46b117cb25cbb94684b 462 SUPERFAMILY SSF53649 26 447 1.7E-127 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 L21SP3_RS10650 7240c7358b12c46b117cb25cbb94684b 462 Gene3D G3DSA:3.30.1120.10 396 457 1.4E-18 T 09-03-2017 L21SP3_RS10650 7240c7358b12c46b117cb25cbb94684b 462 Gene3D G3DSA:3.40.720.10 26 395 1.8E-112 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 L21SP3_RS03170 8ef36904622fde5f4c00f23c6f9784a4 560 SUPERFAMILY SSF49785 421 554 1.19E-8 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS03170 8ef36904622fde5f4c00f23c6f9784a4 560 Pfam PF08305 NPCBM/NEW2 domain 447 554 1.1E-8 T 09-03-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module L21SP3_RS03170 8ef36904622fde5f4c00f23c6f9784a4 560 Pfam PF04773 FecR protein 190 272 1.4E-6 T 09-03-2017 IPR006860 FecR protein L21SP3_RS10160 fbe7840578138270fa81289031194fca 324 Pfam PF00756 Putative esterase 47 193 7.4E-19 T 09-03-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 L21SP3_RS10160 fbe7840578138270fa81289031194fca 324 Gene3D G3DSA:3.40.50.1820 228 292 7.0E-48 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS10160 fbe7840578138270fa81289031194fca 324 Gene3D G3DSA:3.40.50.1820 2 196 7.0E-48 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS10160 fbe7840578138270fa81289031194fca 324 SUPERFAMILY SSF53474 39 292 6.17E-35 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold L21SP3_RS07490 6b0833dcbc0b12fa4701c929eb6a4ae0 901 SUPERFAMILY SSF49899 453 671 2.32E-24 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS07490 6b0833dcbc0b12fa4701c929eb6a4ae0 901 Gene3D G3DSA:2.60.40.10 297 356 1.5E-4 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS07490 6b0833dcbc0b12fa4701c929eb6a4ae0 901 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 528 666 4.5E-20 T 09-03-2017 L21SP3_RS07490 6b0833dcbc0b12fa4701c929eb6a4ae0 901 Gene3D G3DSA:2.60.120.200 460 671 8.5E-22 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain L21SP3_RS03985 77ce072d8838b6f510fbd9175dc8fb62 95 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 13 95 3.6E-18 T 09-03-2017 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 L21SP3_RS03985 77ce072d8838b6f510fbd9175dc8fb62 95 Gene3D G3DSA:2.60.40.10 12 68 1.5E-5 T 09-03-2017 IPR013783 Immunoglobulin-like fold L21SP3_RS03985 77ce072d8838b6f510fbd9175dc8fb62 95 SUPERFAMILY SSF81296 12 94 3.36E-20 T 09-03-2017 IPR014756 Immunoglobulin E-set L21SP3_RS07635 45320e9c5d6b96e827752605af8b33dd 432 Gene3D G3DSA:1.25.40.10 274 395 8.4E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS07635 45320e9c5d6b96e827752605af8b33dd 432 Gene3D G3DSA:1.25.40.10 100 176 8.4E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS07635 45320e9c5d6b96e827752605af8b33dd 432 SUPERFAMILY SSF48452 273 391 4.94E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS08500 32528a6e54c1d5ae1bd865fa0ba4365b 213 Pfam PF07589 PEP-CTERM motif 191 210 2.2E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS08500 32528a6e54c1d5ae1bd865fa0ba4365b 213 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 191 211 2.5E-5 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS05435 d92d8c792b52a39553ce903f3dbf3aaa 407 SUPERFAMILY SSF56935 48 355 2.38E-6 T 09-03-2017 L21SP3_RS05435 d92d8c792b52a39553ce903f3dbf3aaa 407 Gene3D G3DSA:2.40.160.10 49 299 2.0E-7 T 09-03-2017 IPR023614 Porin domain L21SP3_RS02335 4c045e0cb9d7789158f7f7a430c03af0 109 Pfam PF05598 Transposase domain (DUF772) 51 104 2.7E-14 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS03675 17061866a0345cf7229316f899bdcca1 534 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 342 487 2.6E-7 T 09-03-2017 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain L21SP3_RS00900 c970b78018361fb84ac2dcb254e0dcdb 1188 Gene3D G3DSA:1.25.40.10 141 191 2.1E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00900 c970b78018361fb84ac2dcb254e0dcdb 1188 Gene3D G3DSA:1.25.40.10 559 611 2.1E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS00900 c970b78018361fb84ac2dcb254e0dcdb 1188 PRINTS PR00811 Bacterial general secretion pathway protein D signature 982 1006 2.5E-8 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS00900 c970b78018361fb84ac2dcb254e0dcdb 1188 PRINTS PR00811 Bacterial general secretion pathway protein D signature 904 914 2.5E-8 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS00900 c970b78018361fb84ac2dcb254e0dcdb 1188 PRINTS PR00811 Bacterial general secretion pathway protein D signature 1136 1154 2.5E-8 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS00900 c970b78018361fb84ac2dcb254e0dcdb 1188 PRINTS PR00811 Bacterial general secretion pathway protein D signature 1159 1173 2.5E-8 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS00900 c970b78018361fb84ac2dcb254e0dcdb 1188 Pfam PF00263 Bacterial type II and III secretion system protein 986 1171 2.0E-26 T 09-03-2017 IPR004846 Type II/III secretion system GO:0009306 L21SP3_RS01055 7770f9a1dc579b7309beeb5ad535b84c 498 SUPERFAMILY SSF56322 23 486 1.01E-143 T 09-03-2017 IPR005801 ADC synthase GO:0009058 L21SP3_RS01055 7770f9a1dc579b7309beeb5ad535b84c 498 Pfam PF00425 chorismate binding enzyme 225 478 3.7E-95 T 09-03-2017 IPR015890 Chorismate-utilising enzyme, C-terminal L21SP3_RS01055 7770f9a1dc579b7309beeb5ad535b84c 498 Pfam PF04715 Anthranilate synthase component I, N terminal region 31 168 1.2E-23 T 09-03-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 L21SP3_RS01055 7770f9a1dc579b7309beeb5ad535b84c 498 PRINTS PR00095 Anthranilate synthase component I signature 435 449 1.5E-24 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 L21SP3_RS01055 7770f9a1dc579b7309beeb5ad535b84c 498 PRINTS PR00095 Anthranilate synthase component I signature 340 353 1.5E-24 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 L21SP3_RS01055 7770f9a1dc579b7309beeb5ad535b84c 498 PRINTS PR00095 Anthranilate synthase component I signature 420 434 1.5E-24 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 L21SP3_RS01055 7770f9a1dc579b7309beeb5ad535b84c 498 PRINTS PR00095 Anthranilate synthase component I signature 326 339 1.5E-24 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 L21SP3_RS01055 7770f9a1dc579b7309beeb5ad535b84c 498 Gene3D G3DSA:3.60.120.10 23 490 7.5E-156 T 09-03-2017 IPR005801 ADC synthase GO:0009058 L21SP3_RS01365 28afdec24b45d8ba5ae4bf21d689356d 387 Pfam PF13177 DNA polymerase III, delta subunit 28 209 2.6E-40 T 09-03-2017 L21SP3_RS01365 28afdec24b45d8ba5ae4bf21d689356d 387 SUPERFAMILY SSF52540 41 94 1.3E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01365 28afdec24b45d8ba5ae4bf21d689356d 387 SUPERFAMILY SSF52540 126 243 1.3E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01365 28afdec24b45d8ba5ae4bf21d689356d 387 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 304 382 1.5E-7 T 09-03-2017 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 L21SP3_RS01365 28afdec24b45d8ba5ae4bf21d689356d 387 Gene3D G3DSA:3.40.50.300 24 208 9.9E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01365 28afdec24b45d8ba5ae4bf21d689356d 387 Gene3D G3DSA:1.20.272.10 310 384 6.1E-4 T 09-03-2017 L21SP3_RS04355 2edbc0228df40cb495b36a409f4bc2bb 420 Pfam PF00263 Bacterial type II and III secretion system protein 216 377 6.8E-41 T 09-03-2017 IPR004846 Type II/III secretion system GO:0009306 L21SP3_RS04355 2edbc0228df40cb495b36a409f4bc2bb 420 PRINTS PR00811 Bacterial general secretion pathway protein D signature 341 359 1.5E-15 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS04355 2edbc0228df40cb495b36a409f4bc2bb 420 PRINTS PR00811 Bacterial general secretion pathway protein D signature 144 154 1.5E-15 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS04355 2edbc0228df40cb495b36a409f4bc2bb 420 PRINTS PR00811 Bacterial general secretion pathway protein D signature 246 256 1.5E-15 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS04355 2edbc0228df40cb495b36a409f4bc2bb 420 PRINTS PR00811 Bacterial general secretion pathway protein D signature 211 235 1.5E-15 T 09-03-2017 IPR001775 GspD/PilQ family L21SP3_RS04355 2edbc0228df40cb495b36a409f4bc2bb 420 PRINTS PR01032 Gene IV protein signature 236 259 4.8E-8 T 09-03-2017 L21SP3_RS04355 2edbc0228df40cb495b36a409f4bc2bb 420 PRINTS PR01032 Gene IV protein signature 357 379 4.8E-8 T 09-03-2017 L21SP3_RS04355 2edbc0228df40cb495b36a409f4bc2bb 420 PRINTS PR01032 Gene IV protein signature 304 332 4.8E-8 T 09-03-2017 L21SP3_RS10525 34f5e84a4769be1d1f4cef7ece8f7696 546 Pfam PF09992 Phosphodiester glycosidase 84 274 3.7E-32 T 09-03-2017 IPR018711 Phosphodiester glycosidase L21SP3_RS01995 4aa2f88959cc4899e72dbf7cbfc1d358 175 Pfam PF00005 ABC transporter 20 167 1.7E-22 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 L21SP3_RS01995 4aa2f88959cc4899e72dbf7cbfc1d358 175 SUPERFAMILY SSF52540 4 167 6.79E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS01995 4aa2f88959cc4899e72dbf7cbfc1d358 175 Gene3D G3DSA:3.40.50.300 2 167 3.9E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10120 b60305bd88ad3a4b80430cfb7d6127ea 231 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 24 228 1.6E-20 T 09-03-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 L21SP3_RS09160 baebc3216809e3cedafd80045f1a01d3 359 Gene3D G3DSA:3.40.50.1010 147 277 2.2E-20 T 09-03-2017 IPR029060 PIN domain-like L21SP3_RS09160 baebc3216809e3cedafd80045f1a01d3 359 SUPERFAMILY SSF88723 147 276 1.96E-15 T 09-03-2017 IPR029060 PIN domain-like L21SP3_RS02080 41b631de37d7d8ab3ae6c52a5bad9d52 166 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 7 101 17.684 T 09-03-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 L21SP3_RS02080 41b631de37d7d8ab3ae6c52a5bad9d52 166 Pfam PF01250 Ribosomal protein S6 10 98 5.1E-22 T 09-03-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02080 41b631de37d7d8ab3ae6c52a5bad9d52 166 TIGRFAM TIGR00166 S6: ribosomal protein bS6 8 99 4.0E-20 T 09-03-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS02080 41b631de37d7d8ab3ae6c52a5bad9d52 166 Gene3D G3DSA:3.30.70.60 8 100 1.7E-25 T 09-03-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 L21SP3_RS02080 41b631de37d7d8ab3ae6c52a5bad9d52 166 SUPERFAMILY SSF54995 7 100 4.97E-24 T 09-03-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 L21SP3_RS01670 d213cd12a88e517976b5920209402a3b 465 Gene3D G3DSA:2.60.120.380 54 175 3.7E-5 T 09-03-2017 L21SP3_RS01670 d213cd12a88e517976b5920209402a3b 465 Gene3D G3DSA:2.60.120.380 299 415 4.6E-7 T 09-03-2017 L21SP3_RS00630 78eff8ce8f67d198350186afdc6c84e6 326 Gene3D G3DSA:3.90.550.10 2 176 2.8E-26 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS00630 78eff8ce8f67d198350186afdc6c84e6 326 SUPERFAMILY SSF53448 2 258 4.64E-47 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS00630 78eff8ce8f67d198350186afdc6c84e6 326 Pfam PF00535 Glycosyl transferase family 2 4 166 3.6E-33 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 L21SP3_RS09230 6d1dedaacda8d94ea24190b06904a2ee 138 SUPERFAMILY SSF48208 14 100 1.33E-10 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS09230 6d1dedaacda8d94ea24190b06904a2ee 138 Pfam PF05592 Bacterial alpha-L-rhamnosidase 11 98 2.5E-31 T 09-03-2017 IPR008902 Bacterial alpha-L-rhamnosidase L21SP3_RS00195 c031a5ef72fa2fbccb07ae6595a3e6f0 249 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 227 247 4.2E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS00015 71647fc96ec555b2d3bf9a458e2c573c 791 SUPERFAMILY SSF48208 99 137 1.42E-21 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS00015 71647fc96ec555b2d3bf9a458e2c573c 791 SUPERFAMILY SSF48208 180 393 1.42E-21 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 L21SP3_RS00015 71647fc96ec555b2d3bf9a458e2c573c 791 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 48 554 2.1E-145 T 09-03-2017 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 L21SP3_RS00015 71647fc96ec555b2d3bf9a458e2c573c 791 Gene3D G3DSA:1.50.10.10 192 395 2.1E-16 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 L21SP3_RS10465 9b69b70ad44941d33f4449d337e2668a 515 SMART SM00382 268 391 9.2E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain L21SP3_RS10465 9b69b70ad44941d33f4449d337e2668a 515 Pfam PF00437 Type II/IV secretion system protein 141 407 3.1E-62 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 L21SP3_RS10465 9b69b70ad44941d33f4449d337e2668a 515 Gene3D G3DSA:3.40.50.300 246 514 3.6E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10465 9b69b70ad44941d33f4449d337e2668a 515 SUPERFAMILY SSF52540 124 512 1.64E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS10465 9b69b70ad44941d33f4449d337e2668a 515 Gene3D G3DSA:3.30.450.90 113 239 1.7E-28 T 09-03-2017 L21SP3_RS10850 ca5be63621b8534347298b475509266e 392 Gene3D G3DSA:1.10.1330.10 331 384 1.1E-4 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS10850 ca5be63621b8534347298b475509266e 392 SUPERFAMILY SSF63446 332 386 2.65E-5 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS01665 d03b937960c8c1dd37da86bc5a5b6dc8 144 Gene3D G3DSA:2.60.120.380 8 113 1.1E-4 T 09-03-2017 L21SP3_RS07865 70a00ae347ab1e65ff506faf8271c5c6 601 SUPERFAMILY SSF48230 86 302 1.92E-31 T 09-03-2017 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 L21SP3_RS07865 70a00ae347ab1e65ff506faf8271c5c6 601 Pfam PF07940 Heparinase II/III-like protein 376 535 1.4E-13 T 09-03-2017 IPR012480 Heparinase II/III-like GO:0016829 L21SP3_RS11040 1017d041704269788159a97eb6884848 341 Pfam PF01757 Acyltransferase family 5 322 1.9E-24 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 L21SP3_RS09180 89dfb8277dce998f01d64733b60aa66a 112 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 10 99 5.8E-22 T 09-03-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP3_RS09180 89dfb8277dce998f01d64733b60aa66a 112 Gene3D G3DSA:3.30.420.130 1 101 2.5E-27 T 09-03-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP3_RS09180 89dfb8277dce998f01d64733b60aa66a 112 SUPERFAMILY SSF53146 1 111 1.44E-28 T 09-03-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis L21SP3_RS10945 7c83d7fd794b876c20c17ae24e5829b0 495 SUPERFAMILY SSF50630 311 408 9.65E-8 T 09-03-2017 IPR021109 Aspartic peptidase domain L21SP3_RS10945 7c83d7fd794b876c20c17ae24e5829b0 495 Pfam PF13650 Aspartyl protease 311 398 5.0E-10 T 09-03-2017 L21SP3_RS04670 7972b20f962488a970b43fbdbf93cd32 125 Gene3D G3DSA:3.30.1300.30 48 118 1.7E-7 T 09-03-2017 L21SP3_RS04670 7972b20f962488a970b43fbdbf93cd32 125 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 25 4.5E-4 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS04670 7972b20f962488a970b43fbdbf93cd32 125 SUPERFAMILY SSF54523 48 120 2.09E-7 T 09-03-2017 L21SP3_RS04670 7972b20f962488a970b43fbdbf93cd32 125 Pfam PF02501 Type II secretion system (T2SS), protein I 48 120 3.2E-9 T 09-03-2017 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 L21SP3_RS06005 3773b8c39960ad04af64cd468f3b7fec 409 Gene3D G3DSA:3.90.1150.10 263 407 5.3E-33 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 L21SP3_RS06005 3773b8c39960ad04af64cd468f3b7fec 409 SUPERFAMILY SSF53383 2 408 3.86E-77 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase L21SP3_RS06005 3773b8c39960ad04af64cd468f3b7fec 409 Pfam PF00155 Aminotransferase class I and II 35 405 2.0E-31 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 L21SP3_RS06005 3773b8c39960ad04af64cd468f3b7fec 409 TIGRFAM TIGR03542 DAPAT_plant: LL-diaminopimelate aminotransferase 3 407 6.7E-189 T 09-03-2017 IPR019942 LL-diaminopimelate aminotransferase GO:0009089|GO:0010285 KEGG: 00300+2.6.1.83|MetaCyc: PWY-5097 L21SP3_RS06005 3773b8c39960ad04af64cd468f3b7fec 409 Gene3D G3DSA:3.40.640.10 50 262 3.0E-39 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 L21SP3_RS06005 3773b8c39960ad04af64cd468f3b7fec 409 Hamap MF_01642 LL-diaminopimelate aminotransferase [dapL]. 3 408 55.168 T 09-03-2017 IPR019942 LL-diaminopimelate aminotransferase GO:0009089|GO:0010285 KEGG: 00300+2.6.1.83|MetaCyc: PWY-5097 L21SP3_RS10090 910e7e149e55dfc87ec950d172144381 490 Pfam PF03773 Predicted permease 42 487 3.6E-72 T 09-03-2017 IPR005524 Predicted permease DUF318 L21SP3_RS07835 dfb6aaf9ca2d6559ba2483c740433f58 442 Pfam PF02646 RmuC family 134 421 4.7E-90 T 09-03-2017 IPR003798 DNA recombination RmuC L21SP3_RS11470 586f58239cc3530ba829269bb1a46e90 332 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 126 209 2.8E-25 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 L21SP3_RS11470 586f58239cc3530ba829269bb1a46e90 332 PRINTS PR00394 RHS protein signature 177 196 2.0E-6 T 09-03-2017 IPR001826 RHS protein L21SP3_RS11470 586f58239cc3530ba829269bb1a46e90 332 PRINTS PR00394 RHS protein signature 154 174 2.0E-6 T 09-03-2017 IPR001826 RHS protein L21SP3_RS09210 6a7d2b86c6c5615fd0faa290e958fdb1 110 ProDom PD050957 AF2391 PREDICTED 1 33 9.0E-7 T 09-03-2017 L21SP3_RS08925 592d735d7d5376322780c596370551d0 318 Gene3D G3DSA:3.40.50.2300 154 310 2.6E-41 T 09-03-2017 L21SP3_RS08925 592d735d7d5376322780c596370551d0 318 Gene3D G3DSA:3.40.50.2300 32 153 2.6E-35 T 09-03-2017 L21SP3_RS08925 592d735d7d5376322780c596370551d0 318 SUPERFAMILY SSF53822 34 310 3.46E-72 T 09-03-2017 IPR028082 Periplasmic binding protein-like I L21SP3_RS08925 592d735d7d5376322780c596370551d0 318 Pfam PF13407 Periplasmic binding protein domain 38 291 1.3E-53 T 09-03-2017 IPR025997 Periplasmic binding protein L21SP3_RS02910 20350ba86a1bb056554add7a8b4fdfe2 484 Pfam PF00474 Sodium:solute symporter family 33 427 7.4E-49 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS00185 d1227d8ec49eb0cc8d68f016e5e35337 243 Pfam PF12679 ABC-2 family transporter protein 59 189 8.9E-7 T 09-03-2017 IPR032688 ABC-2 family transporter protein GO:0006810 L21SP3_RS00075 a6436e20f66325975c9b21e601202eef 277 Pfam PF02517 CAAX protease self-immunity 165 272 2.6E-10 T 09-03-2017 IPR003675 CAAX amino terminal protease GO:0016020 L21SP3_RS07565 2ed35032035478db45e418568756f95f 373 SUPERFAMILY SSF75005 35 339 8.71E-28 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS07565 2ed35032035478db45e418568756f95f 373 Gene3D G3DSA:2.115.10.20 35 348 1.9E-22 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain L21SP3_RS07565 2ed35032035478db45e418568756f95f 373 Pfam PF04616 Glycosyl hydrolases family 43 69 262 3.2E-7 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 L21SP3_RS01450 195f47ac9b1bc2246f79ecd5aa337137 399 Pfam PF05128 Domain of unknown function (DUF697) 256 395 1.7E-13 T 09-03-2017 IPR021147 Protein of unknown function DUF697 L21SP3_RS08430 cd6acf3e10bcaa9749e6beeda52168be 288 Pfam PF02361 Cobalt transport protein 55 247 9.8E-17 T 09-03-2017 IPR003339 ABC/ECF transporter, transmembrane component L21SP3_RS04725 df7084f908b4f090c232c7c1be6ffd49 84 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 20 67 4.6E-8 T 09-03-2017 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter L21SP3_RS10340 0af5d33f6a22db12e1ff7afa5de3dae1 200 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 26 100 1.2E-18 T 09-03-2017 IPR025159 Transcriptional regulator, AbiEi antitoxin L21SP3_RS03730 93fd8d4eb6cf7b5edb68ff35cdf3682c 406 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 217 385 3.9E-59 T 09-03-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 L21SP3_RS03730 93fd8d4eb6cf7b5edb68ff35cdf3682c 406 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 212 389 1.1E-46 T 09-03-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 L21SP3_RS03730 93fd8d4eb6cf7b5edb68ff35cdf3682c 406 Pfam PF02397 Bacterial sugar transferase 3 148 1.2E-8 T 09-03-2017 IPR003362 Bacterial sugar transferase L21SP3_RS09855 a744c57238c3b1d96ef87e080454d90d 203 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 74 4.4E-15 T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 L21SP3_RS09855 a744c57238c3b1d96ef87e080454d90d 203 PIRSF PIRSF000847 1 203 7.6E-36 T 09-03-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 L21SP3_RS09855 a744c57238c3b1d96ef87e080454d90d 203 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 52 74 - T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 L21SP3_RS09595 4c1c369cd22b4135a00bc464092a9e60 131 Pfam PF03703 Bacterial PH domain 43 125 1.3E-10 T 09-03-2017 IPR005182 Domain of unknown function DUF304 L21SP3_RS06850 71fb3fe0dd3aacbdb932099dea6c2ac4 302 SUPERFAMILY SSF103481 74 145 1.44E-11 T 09-03-2017 L21SP3_RS06850 71fb3fe0dd3aacbdb932099dea6c2ac4 302 Pfam PF00892 EamA-like transporter family 2 143 8.9E-12 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 L21SP3_RS06850 71fb3fe0dd3aacbdb932099dea6c2ac4 302 SUPERFAMILY SSF103481 201 300 1.28E-6 T 09-03-2017 L21SP3_RS09030 f12ab1eb548034dfc077dbf2796a2c00 320 SUPERFAMILY SSF50494 40 149 1.2E-7 T 09-03-2017 IPR009003 Peptidase S1, PA clan L21SP3_RS09030 f12ab1eb548034dfc077dbf2796a2c00 320 SUPERFAMILY SSF50494 177 231 1.2E-7 T 09-03-2017 IPR009003 Peptidase S1, PA clan L21SP3_RS09030 f12ab1eb548034dfc077dbf2796a2c00 320 SUPERFAMILY SSF63446 266 315 1.57E-7 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS09030 f12ab1eb548034dfc077dbf2796a2c00 320 ProSitePatterns PS00018 EF-hand calcium-binding domain. 296 308 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS09030 f12ab1eb548034dfc077dbf2796a2c00 320 Gene3D G3DSA:1.10.1330.10 264 314 6.4E-7 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS04195 412ef69c0a00d2f5bde2552c57793362 404 Gene3D G3DSA:3.30.460.10 10 147 1.4E-45 T 09-03-2017 L21SP3_RS04195 412ef69c0a00d2f5bde2552c57793362 404 SUPERFAMILY SSF81301 8 143 6.21E-38 T 09-03-2017 L21SP3_RS04195 412ef69c0a00d2f5bde2552c57793362 404 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 174 230 4.4E-17 T 09-03-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 L21SP3_RS04195 412ef69c0a00d2f5bde2552c57793362 404 Gene3D G3DSA:1.10.3090.10 148 370 6.3E-44 T 09-03-2017 L21SP3_RS04195 412ef69c0a00d2f5bde2552c57793362 404 SUPERFAMILY SSF81891 145 394 1.31E-46 T 09-03-2017 L21SP3_RS04195 412ef69c0a00d2f5bde2552c57793362 404 Pfam PF01743 Poly A polymerase head domain 28 147 1.2E-34 T 09-03-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 L21SP3_RS04410 62f8c62d9f7bb52c4449e12289247bec 140 Pfam PF03692 Putative zinc- or iron-chelating domain 14 115 2.1E-11 T 09-03-2017 IPR005358 Putative zinc- or iron-chelating domain containing protein L21SP3_RS00070 9b6dce4ca94a1aa354e33e59f6dc011e 1059 Pfam PF13502 AsmA-like C-terminal region 584 666 6.7E-6 T 09-03-2017 IPR032712 AsmA-like, C-terminal L21SP3_RS00070 9b6dce4ca94a1aa354e33e59f6dc011e 1059 Pfam PF13502 AsmA-like C-terminal region 862 1016 1.8E-5 T 09-03-2017 IPR032712 AsmA-like, C-terminal L21SP3_RS11190 7a420cd28cb986172a75ab70cfbd52a5 60 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 1 56 8.2E-9 T 09-03-2017 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 L21SP3_RS11190 7a420cd28cb986172a75ab70cfbd52a5 60 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 1 56 1.9E-10 T 09-03-2017 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 L21SP3_RS05400 df9ba85cbdff5f15c4bf207ebe08655f 849 Gene3D G3DSA:3.20.20.70 521 598 1.7E-6 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 L21SP3_RS04320 cb80a079cf8bba1e581ef24e448843f8 258 Gene3D G3DSA:1.10.1330.10 195 251 6.6E-7 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS04320 cb80a079cf8bba1e581ef24e448843f8 258 ProSitePatterns PS00018 EF-hand calcium-binding domain. 235 247 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS04320 cb80a079cf8bba1e581ef24e448843f8 258 SUPERFAMILY SSF63446 196 251 4.71E-7 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS00775 693b276277a489d61e6c2dc05665db04 562 Pfam PF00474 Sodium:solute symporter family 34 421 9.3E-26 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 L21SP3_RS07800 b003ef1630557a65a4fd3fb948e9401d 540 Pfam PF01609 Transposase DDE domain 200 470 2.2E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS07800 b003ef1630557a65a4fd3fb948e9401d 540 SUPERFAMILY SSF53098 160 516 1.14E-15 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS09010 59c41e59f03348495c1fcb15d724b601 451 Pfam PF04326 Putative DNA-binding domain 5 122 4.0E-12 T 09-03-2017 IPR007421 Schlafen, AAA domain GO:0005524 L21SP3_RS09010 59c41e59f03348495c1fcb15d724b601 451 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 277 339 4.5E-12 T 09-03-2017 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain L21SP3_RS03205 9ad43b8f26da26984df080d6bf26eb8a 444 Pfam PF00881 Nitroreductase family 67 225 1.2E-10 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 L21SP3_RS03205 9ad43b8f26da26984df080d6bf26eb8a 444 SUPERFAMILY SSF52317 279 415 9.58E-16 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS03205 9ad43b8f26da26984df080d6bf26eb8a 444 Gene3D G3DSA:3.40.50.880 258 416 5.5E-16 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like L21SP3_RS03205 9ad43b8f26da26984df080d6bf26eb8a 444 Gene3D G3DSA:3.40.109.10 51 225 6.8E-11 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 L21SP3_RS03205 9ad43b8f26da26984df080d6bf26eb8a 444 Pfam PF01965 DJ-1/PfpI family 282 417 6.7E-15 T 09-03-2017 IPR002818 DJ-1/PfpI L21SP3_RS03205 9ad43b8f26da26984df080d6bf26eb8a 444 SUPERFAMILY SSF55469 64 229 2.36E-11 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 L21SP3_RS08940 126f0c1c65cf879dbeef562e6ace8a2c 167 Pfam PF10882 Bacterial PH domain 66 162 1.0E-13 T 09-03-2017 IPR027783 Bacterial Pleckstrin homology domain-related L21SP3_RS05950 f6eb8d895d6a8613105736236374f186 215 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 30 0.0011 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS00785 f23d7d01b970a027aee7557a694ac2d7 928 Gene3D G3DSA:3.20.20.80 516 780 1.4E-19 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 L21SP3_RS00785 f23d7d01b970a027aee7557a694ac2d7 928 SUPERFAMILY SSF51445 523 786 8.13E-12 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS01015 f0ad9bd6dd91a5ab060396c1c8a0b648 80 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 4 76 3.2E-31 T 09-03-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS01015 f0ad9bd6dd91a5ab060396c1c8a0b648 80 Pfam PF00550 Phosphopantetheine attachment site 8 75 2.9E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS01015 f0ad9bd6dd91a5ab060396c1c8a0b648 80 Hamap MF_01217 Acyl carrier protein [acpP]. 5 79 20.492 T 09-03-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS01015 f0ad9bd6dd91a5ab060396c1c8a0b648 80 Gene3D G3DSA:1.10.1200.10 4 77 5.0E-30 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS01015 f0ad9bd6dd91a5ab060396c1c8a0b648 80 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 36 75 9.0E-8 T 09-03-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 L21SP3_RS01015 f0ad9bd6dd91a5ab060396c1c8a0b648 80 SUPERFAMILY SSF47336 1 78 1.24E-22 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain L21SP3_RS01015 f0ad9bd6dd91a5ab060396c1c8a0b648 80 ProSitePatterns PS00012 Phosphopantetheine attachment site. 34 49 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site L21SP3_RS00380 74ce8a20fa6de4c1369ae15440dd1d7a 553 Pfam PF08305 NPCBM/NEW2 domain 414 524 4.0E-9 T 09-03-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module L21SP3_RS00380 74ce8a20fa6de4c1369ae15440dd1d7a 553 SUPERFAMILY SSF49785 410 525 3.32E-5 T 09-03-2017 IPR008979 Galactose-binding domain-like L21SP3_RS00380 74ce8a20fa6de4c1369ae15440dd1d7a 553 Pfam PF04773 FecR protein 182 264 4.4E-7 T 09-03-2017 IPR006860 FecR protein L21SP3_RS04140 68842366f4946035c1ea5c0c648fc19c 332 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 2 325 13.636 T 09-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 L21SP3_RS04140 68842366f4946035c1ea5c0c648fc19c 332 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 4 320 2.0E-59 T 09-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 L21SP3_RS04915 114c5a4aba534a0b80aa75c37baab8d3 461 Pfam PF13598 Domain of unknown function (DUF4139) 175 460 2.5E-9 T 09-03-2017 IPR011935 Conserved hypothetical protein CHP02231 L21SP3_RS10425 620ebb2797e3825b6c714378a46b9a8c 415 Pfam PF01098 Cell cycle protein 99 408 3.7E-80 T 09-03-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 L21SP3_RS11385 28330e1ce5420c55e9dc3ca631b63723 185 Pfam PF07977 FabA-like domain 32 149 5.4E-16 T 09-03-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 L21SP3_RS11385 28330e1ce5420c55e9dc3ca631b63723 185 Gene3D G3DSA:3.10.129.10 27 151 2.7E-25 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS11385 28330e1ce5420c55e9dc3ca631b63723 185 SUPERFAMILY SSF54637 32 151 7.25E-23 T 09-03-2017 IPR029069 HotDog domain L21SP3_RS00045 59ce27646683c5903d9f1ba12c22023e 636 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 81 235 1.1E-9 T 09-03-2017 L21SP3_RS02020 bc7c5d4ddaf7253930e7b4d4afe79d6a 74 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 9 73 1.0E-18 T 09-03-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 L21SP3_RS02020 bc7c5d4ddaf7253930e7b4d4afe79d6a 74 SUPERFAMILY SSF117916 3 73 2.29E-24 T 09-03-2017 L21SP3_RS02020 bc7c5d4ddaf7253930e7b4d4afe79d6a 74 Pfam PF01106 NifU-like domain 5 70 5.7E-28 T 09-03-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 L21SP3_RS08575 9e5a196e11bae74f7318bfba57dd4ec6 153 Pfam PF13518 Helix-turn-helix domain 45 96 1.7E-8 T 09-03-2017 L21SP3_RS08575 9e5a196e11bae74f7318bfba57dd4ec6 153 Gene3D G3DSA:1.10.10.10 43 90 2.3E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain L21SP3_RS08575 9e5a196e11bae74f7318bfba57dd4ec6 153 SUPERFAMILY SSF46689 45 147 3.76E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 L21SP3_RS07720 8a4d99c5007f9731fe1b7fe67410474a 237 Pfam PF14103 Domain of unknown function (DUF4276) 56 157 1.3E-8 T 09-03-2017 IPR025455 Protein of unknown function DUF4276 L21SP3_RS08585 e973fbe35ee4ad88feefb47e69b2adb4 69 Pfam PF13683 Integrase core domain 1 39 1.4E-6 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS06010 ac0c5a4124a4355035085ed6c60088d1 484 Pfam PF11028 Protein of unknown function (DUF2723) 61 195 5.4E-10 T 09-03-2017 IPR021280 Protein of unknown function DUF2723 L21SP3_RS03800 65f7e65de3bc9a944525194f6bbed07c 586 Pfam PF01609 Transposase DDE domain 208 506 7.2E-19 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS03800 65f7e65de3bc9a944525194f6bbed07c 586 SUPERFAMILY SSF53098 160 578 4.85E-11 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS03510 4bbf1aa1e3abe68bf51191a040aaeff0 527 Gene3D G3DSA:1.25.40.10 360 430 1.7E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS03510 4bbf1aa1e3abe68bf51191a040aaeff0 527 Gene3D G3DSA:1.25.40.10 464 490 1.7E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS03510 4bbf1aa1e3abe68bf51191a040aaeff0 527 SUPERFAMILY SSF48452 365 492 1.44E-8 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 L21SP3_RS04795 7a2cc8d66338590384d5804a19c34896 202 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 49 81 2.8E-8 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS04795 7a2cc8d66338590384d5804a19c34896 202 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 108 142 4.6E-8 T 09-03-2017 IPR001451 Hexapeptide repeat L21SP3_RS04795 7a2cc8d66338590384d5804a19c34896 202 SUPERFAMILY SSF51161 20 187 2.36E-40 T 09-03-2017 IPR011004 Trimeric LpxA-like L21SP3_RS04795 7a2cc8d66338590384d5804a19c34896 202 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 116 144 - T 09-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 L21SP3_RS04795 7a2cc8d66338590384d5804a19c34896 202 Gene3D G3DSA:2.160.10.10 45 173 3.7E-42 T 09-03-2017 L21SP3_RS08140 c3b66d660c0b0864be0cffa1aa5e932a 174 Pfam PF13274 Protein of unknown function (DUF4065) 36 134 3.3E-22 T 09-03-2017 IPR025272 Domain of unknown function DUF4065 L21SP3_RS08180 7e5a6440115988419fd234374eb3fcba 156 Pfam PF13673 Acetyltransferase (GNAT) domain 38 130 9.2E-7 T 09-03-2017 IPR000182 GNAT domain GO:0008080 L21SP3_RS08180 7e5a6440115988419fd234374eb3fcba 156 Gene3D G3DSA:3.40.630.30 8 153 3.7E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS08180 7e5a6440115988419fd234374eb3fcba 156 SUPERFAMILY SSF55729 8 126 3.72E-16 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase L21SP3_RS10830 24655a7fdb73f7feddfedc6eda18a2e2 355 Pfam PF03773 Predicted permease 14 304 3.5E-46 T 09-03-2017 IPR005524 Predicted permease DUF318 L21SP3_RS08235 d7b95bed1be538356edd6a7230388a3d 333 Pfam PF13310 Virulence protein RhuM family 63 309 2.1E-100 T 09-03-2017 IPR011204 Virulence protein RhuM-like L21SP3_RS08235 d7b95bed1be538356edd6a7230388a3d 333 PIRSF PIRSF015268 1 333 2.4E-125 T 09-03-2017 IPR011204 Virulence protein RhuM-like L21SP3_RS08550 14de781ece4abf279981ed50e3b85519 178 PIRSF PIRSF006135 3 173 4.9E-54 T 09-03-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 L21SP3_RS08550 14de781ece4abf279981ed50e3b85519 178 Gene3D G3DSA:3.40.50.300 4 171 1.6E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS08550 14de781ece4abf279981ed50e3b85519 178 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 5 169 5.6E-57 T 09-03-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 L21SP3_RS08550 14de781ece4abf279981ed50e3b85519 178 SUPERFAMILY SSF52540 4 171 2.45E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase L21SP3_RS05515 d210acb025065c69789d62e028412b73 298 Pfam PF08759 Domain of unknown function (DUF1792) 80 274 1.4E-49 T 09-03-2017 IPR014869 Domain of unknown function DUF1792 L21SP3_RS04470 cf28442c785ec20bd3cfc6737791a5cd 232 Pfam PF07589 PEP-CTERM motif 208 229 2.6E-6 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS04470 cf28442c785ec20bd3cfc6737791a5cd 232 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 208 231 1.2E-6 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS03025 30cfc47326f9c48f7f1c89d246a2ca32 317 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 10 309 4.8E-62 T 09-03-2017 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 L21SP3_RS03025 30cfc47326f9c48f7f1c89d246a2ca32 317 Pfam PF01699 Sodium/calcium exchanger protein 173 314 3.8E-24 T 09-03-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 L21SP3_RS03025 30cfc47326f9c48f7f1c89d246a2ca32 317 Pfam PF01699 Sodium/calcium exchanger protein 9 148 9.4E-23 T 09-03-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 L21SP3_RS02140 060631af361858702b053706383a15f3 330 SUPERFAMILY SSF51430 13 328 7.86E-83 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain L21SP3_RS02140 060631af361858702b053706383a15f3 330 Gene3D G3DSA:3.20.20.100 13 328 7.5E-82 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain L21SP3_RS02140 060631af361858702b053706383a15f3 330 Pfam PF00248 Aldo/keto reductase family 26 327 5.9E-63 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain L21SP3_RS01360 881a52aea96e824a46849d7dba746382 404 Pfam PF04468 PSP1 C-terminal conserved region 91 174 2.5E-24 T 09-03-2017 IPR007557 PSP1, C-terminal L21SP3_RS03680 3d234b987d472d4f3dd0aed3aca238d0 404 Pfam PF04230 Polysaccharide pyruvyl transferase 18 338 2.2E-35 T 09-03-2017 IPR007345 Polysaccharide pyruvyl transferase L21SP3_RS04350 feb7f0536f3e41a4a655636e82e5368c 492 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 267 385 1.6E-8 T 09-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain L21SP3_RS04350 feb7f0536f3e41a4a655636e82e5368c 492 Gene3D G3DSA:2.40.50.100 299 308 3.9E-4 T 09-03-2017 L21SP3_RS04350 feb7f0536f3e41a4a655636e82e5368c 492 Gene3D G3DSA:2.40.50.100 79 98 3.9E-4 T 09-03-2017 L21SP3_RS04350 feb7f0536f3e41a4a655636e82e5368c 492 Gene3D G3DSA:1.20.5.500 271 298 3.9E-4 T 09-03-2017 L21SP3_RS11700 fbb4ba85a06d406d9a0840b50bb22525 1310 TIGRFAM TIGR04330 cas_Cpf1: CRISPR-associated protein Cpf1, subtype PREFRAN 2 1309 0.0 T 09-03-2017 IPR027620 CRISPR-associated protein Cpf1, PREFRAN subtype L21SP3_RS03360 d3d2517fa5712226f5fcfb5de1938b8b 144 Pfam PF07589 PEP-CTERM motif 123 143 2.6E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS09370 a626d95034b0fdb2381818db434b9c9e 547 SUPERFAMILY SSF50939 46 362 1.65E-48 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS09370 a626d95034b0fdb2381818db434b9c9e 547 Gene3D G3DSA:2.120.10.10 47 370 9.3E-48 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS09370 a626d95034b0fdb2381818db434b9c9e 547 Pfam PF13088 BNR repeat-like domain 61 341 8.5E-27 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 L21SP3_RS11335 090e52b05920eb807c8eab9e2791f915 230 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 209 228 0.0011 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS04275 c9b3aa751c425f82a325a0a6e539ab47 596 Pfam PF05580 SpoIVB peptidase S55 37 113 4.6E-5 T 09-03-2017 IPR008763 Peptidase S55, SpoIVB L21SP3_RS07240 fabbe75d11a7161e0d4997e217e54bda 77 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 9 57 4.5E-6 T 09-03-2017 IPR010260 Prophage CP4-57 regulatory protein (AlpA) L21SP3_RS04415 63cbe832a188b105659ce19819b03744 137 Pfam PF03692 Putative zinc- or iron-chelating domain 29 100 2.6E-5 T 09-03-2017 IPR005358 Putative zinc- or iron-chelating domain containing protein L21SP3_RS00845 9c8b45bb958d7afa5517cf1276a6f9ff 147 Pfam PF14294 Domain of unknown function (DUF4372) 7 73 2.0E-15 T 09-03-2017 IPR025399 Domain of unknown function DUF4372 L21SP3_RS06295 56300d4d3d836087476d1da0666f8a16 205 Gene3D G3DSA:3.30.700.10 9 73 6.8E-4 T 09-03-2017 L21SP3_RS06295 56300d4d3d836087476d1da0666f8a16 205 SUPERFAMILY SSF54523 9 85 3.61E-10 T 09-03-2017 L21SP3_RS06295 56300d4d3d836087476d1da0666f8a16 205 SUPERFAMILY SSF54523 145 204 4.55E-5 T 09-03-2017 L21SP3_RS03965 6f3cee7ca01adbd80b10dbae9da9f76b 204 PIRSF PIRSF006102 4 204 7.7E-61 T 09-03-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 L21SP3_RS03965 6f3cee7ca01adbd80b10dbae9da9f76b 204 Pfam PF02508 Rnf-Nqr subunit, membrane protein 10 190 2.2E-56 T 09-03-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 L21SP3_RS08815 12312179724546c77d6050514c35e274 211 Pfam PF14487 Domain of unknown function (DUF4433) 9 211 1.2E-50 T 09-03-2017 IPR029494 Domain of unknown function DUF4433 L21SP3_RS07260 949e1554947895c24284c4e5440e19a1 158 Gene3D G3DSA:1.10.260.40 95 155 8.6E-5 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 L21SP3_RS07185 969f5e3e6f1bb5dab7906ff86a6b91c4 67 Pfam PF12669 Virus attachment protein p12 family 4 48 5.5E-11 T 09-03-2017 L21SP3_RS01385 5ec5fd56a17d1bd2795e557b2d6e54e4 296 Gene3D G3DSA:1.20.5.50 112 174 8.7E-4 T 09-03-2017 L21SP3_RS00840 596f6099720ac688502da107ec0ff5ec 540 Pfam PF01609 Transposase DDE domain 200 470 2.2E-21 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS00840 596f6099720ac688502da107ec0ff5ec 540 SUPERFAMILY SSF53098 160 516 2.43E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS09925 e1144b189227103aa0efb722e8510cbb 1003 Gene3D G3DSA:2.60.450.10 246 345 1.5E-6 T 09-03-2017 L21SP3_RS09925 e1144b189227103aa0efb722e8510cbb 1003 Gene3D G3DSA:2.60.450.10 25 74 1.5E-6 T 09-03-2017 L21SP3_RS00265 2319228a5277cdd59c5e9f1f74ec81a4 319 Pfam PF03547 Membrane transport protein 171 312 2.9E-14 T 09-03-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 L21SP3_RS00265 2319228a5277cdd59c5e9f1f74ec81a4 319 Pfam PF03547 Membrane transport protein 13 119 5.2E-9 T 09-03-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 L21SP3_RS00065 c155c63dde8cf3a1e0cde1994e244623 257 SUPERFAMILY SSF103088 131 255 2.62E-25 T 09-03-2017 IPR006665 OmpA-like domain L21SP3_RS00065 c155c63dde8cf3a1e0cde1994e244623 257 Gene3D G3DSA:3.30.1330.60 128 255 2.1E-28 T 09-03-2017 IPR006665 OmpA-like domain L21SP3_RS00065 c155c63dde8cf3a1e0cde1994e244623 257 Pfam PF00691 OmpA family 141 245 1.9E-19 T 09-03-2017 IPR006665 OmpA-like domain L21SP3_RS05715 a3a1c42380bb31992e15639730ef0d9b 297 Pfam PF00892 EamA-like transporter family 147 265 5.7E-12 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 L21SP3_RS05715 a3a1c42380bb31992e15639730ef0d9b 297 Pfam PF00892 EamA-like transporter family 10 136 1.4E-9 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 L21SP3_RS05715 a3a1c42380bb31992e15639730ef0d9b 297 SUPERFAMILY SSF103481 194 267 6.41E-9 T 09-03-2017 L21SP3_RS08490 be0e99bd8878f7f645cf360edce0cea0 499 Pfam PF00665 Integrase core domain 124 241 1.4E-15 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 L21SP3_RS08490 be0e99bd8878f7f645cf360edce0cea0 499 Gene3D G3DSA:3.30.420.10 125 247 7.8E-5 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS08490 be0e99bd8878f7f645cf360edce0cea0 499 SUPERFAMILY SSF53098 125 250 2.31E-5 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 L21SP3_RS07025 9be51694ddb915f4edf9d66ee219eaf6 78 Pfam PF11146 Protein of unknown function (DUF2905) 10 71 7.2E-19 T 09-03-2017 IPR021320 Protein of unknown function DUF2905 L21SP3_RS00725 b0b7ad1d5d0e343da85c4b0acdd5966f 439 Pfam PF03631 Virulence factor BrkB 44 303 1.1E-48 T 09-03-2017 IPR017039 Virulence factor BrkB L21SP3_RS00725 b0b7ad1d5d0e343da85c4b0acdd5966f 439 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 123 303 7.0E-36 T 09-03-2017 IPR017039 Virulence factor BrkB L21SP3_RS05980 1949efa8964748245095de63a387cc24 338 SUPERFAMILY SSF64182 24 319 1.57E-53 T 09-03-2017 L21SP3_RS05980 1949efa8964748245095de63a387cc24 338 Pfam PF01368 DHH family 25 172 1.7E-7 T 09-03-2017 IPR001667 DDH domain L21SP3_RS05980 1949efa8964748245095de63a387cc24 338 Gene3D G3DSA:3.90.1640.10 24 214 8.7E-22 T 09-03-2017 L21SP3_RS05980 1949efa8964748245095de63a387cc24 338 Pfam PF02272 DHHA1 domain 275 321 6.4E-9 T 09-03-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 L21SP3_RS01265 ea65e1457c4866484309296364eb7b68 475 PIRSF PIRSF006603 2 462 1.3E-66 T 09-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 L21SP3_RS01265 ea65e1457c4866484309296364eb7b68 475 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 430 5.9E-66 T 09-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 L21SP3_RS01265 ea65e1457c4866484309296364eb7b68 475 Pfam PF01554 MatE 260 414 8.7E-16 T 09-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 L21SP3_RS01265 ea65e1457c4866484309296364eb7b68 475 Pfam PF01554 MatE 23 182 2.2E-23 T 09-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 L21SP3_RS02325 047250ff7f86ecfb80d9d75d4b97c24f 465 SUPERFAMILY SSF54523 379 445 2.82E-5 T 09-03-2017 L21SP3_RS01625 ef2a28cfc1cae7dd71f1275572a52859 426 Pfam PF01566 Natural resistance-associated macrophage protein 38 396 1.7E-59 T 09-03-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 L21SP3_RS11030 e4781854ae249d6b14daca01e342061a 239 SUPERFAMILY SSF51735 3 237 6.62E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS11030 e4781854ae249d6b14daca01e342061a 239 Gene3D G3DSA:3.40.50.720 3 237 1.3E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain L21SP3_RS11030 e4781854ae249d6b14daca01e342061a 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 3.5E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS11030 e4781854ae249d6b14daca01e342061a 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.5E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS11030 e4781854ae249d6b14daca01e342061a 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 3.5E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS11030 e4781854ae249d6b14daca01e342061a 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.5E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS11030 e4781854ae249d6b14daca01e342061a 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 3.5E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR L21SP3_RS11030 e4781854ae249d6b14daca01e342061a 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 235 1.4E-27 T 09-03-2017 L21SP3_RS11510 9694aaffe9488417beb01de10dfd21c1 267 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 75 106 3.2E-10 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 L21SP3_RS11510 9694aaffe9488417beb01de10dfd21c1 267 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 12 67 1.1E-14 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 L21SP3_RS02660 aca58ab504aa99b854f00a145fe5897d 147 Pfam PF10825 Protein of unknown function (DUF2752) 49 97 2.9E-9 T 09-03-2017 IPR021215 Protein of unknown function DUF2752 L21SP3_RS11735 792ba07647665226104b2660bd89a433 146 Pfam PF13274 Protein of unknown function (DUF4065) 25 118 1.2E-19 T 09-03-2017 IPR025272 Domain of unknown function DUF4065 L21SP3_RS11290 3dc4fe82b51d00c14872477ec5103bbb 184 Pfam PF02417 Chromate transporter 11 172 5.9E-40 T 09-03-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 L21SP3_RS01100 4a6b3bfb7bf3b2e9100abcebb6de4b3e 276 Pfam PF01925 Sulfite exporter TauE/SafE 7 268 1.7E-27 T 09-03-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 L21SP3_RS02475 03b1e63a8dbd8d9a86398bf5fbda2e4f 255 Pfam PF06629 MltA-interacting protein MipA 39 255 1.4E-37 T 09-03-2017 IPR010583 MltA-interacting MipA L21SP3_RS05330 b95afbe3d90d13407178572d3a62f280 299 Pfam PF04784 Protein of unknown function, DUF547 97 209 4.9E-16 T 09-03-2017 IPR006869 Domain of unknown function DUF547 L21SP3_RS06585 6ab5dbb6883af597f75131f262016635 231 Pfam PF04367 Protein of unknown function (DUF502) 78 182 1.8E-26 T 09-03-2017 IPR007462 Protein of unknown function DUF502 L21SP3_RS02570 4eb7b58e950e2318b38755789ffdf8f4 315 SUPERFAMILY SSF53448 164 261 5.62E-13 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS02570 4eb7b58e950e2318b38755789ffdf8f4 315 SUPERFAMILY SSF53448 9 117 5.62E-13 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases L21SP3_RS10315 4a101c129b852cb57b81673e2525a128 528 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 493 9.5E-42 T 09-03-2017 IPR005495 Permease LptG/LptF-related GO:0016021 L21SP3_RS05335 920d0664070a0d9836509078a6f66767 172 Pfam PF03692 Putative zinc- or iron-chelating domain 43 127 1.8E-7 T 09-03-2017 IPR005358 Putative zinc- or iron-chelating domain containing protein L21SP3_RS09540 96c6d2e506aa420a7a8eedb3d3cca406 422 Pfam PF01609 Transposase DDE domain 275 412 1.5E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS09540 96c6d2e506aa420a7a8eedb3d3cca406 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.6E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS01655 96c6d2e506aa420a7a8eedb3d3cca406 422 Pfam PF01609 Transposase DDE domain 275 412 1.5E-6 T 09-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 L21SP3_RS01655 96c6d2e506aa420a7a8eedb3d3cca406 422 Pfam PF05598 Transposase domain (DUF772) 51 125 1.6E-18 T 09-03-2017 IPR008490 Transposase InsH, N-terminal L21SP3_RS00175 90b588b6533aeb34d59f92a668a2dd58 432 Pfam PF14238 Domain of unknown function (DUF4340) 75 248 1.5E-17 T 09-03-2017 IPR025641 Domain of unknown function DUF4340 L21SP3_RS01295 58598ab08c05680370c0eeb2188905a9 59 TIGRFAM TIGR04137 Chlam_Ver_rRNA: Chlam_Verruc_Plancto small basic protein 1 47 2.5E-19 T 09-03-2017 IPR026405 Chlamydiae/Verrucomicrobia/Planctomycetes small basic protein L21SP3_RS00825 2ceb3205c7ff583ed4d7a63f6418140a 414 Pfam PF16257 tagaturonate epimerase 4 389 3.3E-58 T 09-03-2017 IPR032586 Tagaturonate epimerase L21SP3_RS04485 2ceb3205c7ff583ed4d7a63f6418140a 414 Pfam PF16257 tagaturonate epimerase 4 389 3.3E-58 T 09-03-2017 IPR032586 Tagaturonate epimerase L21SP3_RS00835 5161deb1144db79c70877d316ab02b24 566 Pfam PF04773 FecR protein 190 272 5.0E-5 T 09-03-2017 IPR006860 FecR protein L21SP3_RS11355 3dc1f69b25c7eb1e403e4ecdc9cb52f7 381 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 373 2.6E-32 T 09-03-2017 IPR005495 Permease LptG/LptF-related GO:0016021 L21SP3_RS07440 ce787672d1a4bc138b9fa79e99b09cab 161 ProSitePatterns PS00018 EF-hand calcium-binding domain. 135 147 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site L21SP3_RS09260 e20662694705400090271e1caa27dbc8 175 Pfam PF04390 Lipopolysaccharide-assembly 22 170 2.6E-10 T 09-03-2017 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 L21SP3_RS08920 c6a5c7d7ff63a3113f959addaff625ef 331 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 325 9.4E-51 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 L21SP3_RS07020 d827bcbc5cb186a7799bed2e4e76be41 209 Pfam PF01863 Protein of unknown function DUF45 22 81 1.1E-5 T 09-03-2017 IPR002725 Protein of unknown function DUF45 L21SP3_RS07020 d827bcbc5cb186a7799bed2e4e76be41 209 Pfam PF01863 Protein of unknown function DUF45 85 182 8.8E-27 T 09-03-2017 IPR002725 Protein of unknown function DUF45 L21SP3_RS00735 6630bcadab84ecf5d220b85a8950ff53 70 Pfam PF04070 Domain of unknown function (DUF378) 6 59 4.2E-24 T 09-03-2017 IPR007211 Protein of unknown function DUF378 L21SP3_RS08390 b9a630d449a9a78a51907d239a13d1ae 317 Gene3D G3DSA:1.10.1330.10 222 303 1.9E-5 T 09-03-2017 IPR016134 Dockerin domain GO:0000272 L21SP3_RS03615 52306f0de49af57e37b43922983b6428 237 Pfam PF07589 PEP-CTERM motif 213 234 1.4E-4 T 09-03-2017 IPR013424 PEP-CTERM protein-sorting domain L21SP3_RS06275 8519dac4a2f14b5f9b2982b2e18520c7 256 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 29 3.4E-4 T 09-03-2017 IPR012902 Prokaryotic N-terminal methylation site L21SP3_RS07960 fae50ca1f14fcb3bb096715e4763a395 461 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 86 445 3.8E-19 T 09-03-2017 IPR021145 Portal protein, SPP1 Gp6-like L21SP3_RS02875 22d41d3b7de9db34769d8093d6b859eb 397 SUPERFAMILY SSF51445 128 256 2.42E-9 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily L21SP3_RS10625 26591f2b4a215ec652d8b7ab365f23c7 342 Pfam PF01594 Domain of unknown function DUF20 16 317 1.2E-38 T 09-03-2017 IPR002549 Transmembrane protein TqsA-like L21SP3_RS05760 72b6d0e1ee1668a124d21b571c9e5f49 107 Gene3D G3DSA:3.30.460.10 13 106 1.1E-7 T 09-03-2017 L21SP3_RS05485 32e69428fd727a7a01e4ef4eac0a23f4 249 Pfam PF02397 Bacterial sugar transferase 52 228 9.3E-58 T 09-03-2017 IPR003362 Bacterial sugar transferase L21SP3_RS01480 174082f5a200bf894acc1bacb2d5153d 769 Pfam PF03783 Curli production assembly/transport component CsgG 166 247 2.2E-8 T 09-03-2017 IPR005534 Curli production assembly/transport component CsgG GO:0030288 L21SP3_RS01480 174082f5a200bf894acc1bacb2d5153d 769 Pfam PF03783 Curli production assembly/transport component CsgG 496 615 1.2E-5 T 09-03-2017 IPR005534 Curli production assembly/transport component CsgG GO:0030288 L21SP3_RS06755 8984410bb8c45e0fdcecef5fc3a53991 259 Pfam PF04966 Carbohydrate-selective porin, OprB family 2 256 3.0E-34 T 09-03-2017 IPR007049 Carbohydrate-selective porin OprB GO:0005215|GO:0006810|GO:0016021 L21SP3_RS05340 7883b6ed39056c1606556d54d31a6ca8 513 Pfam PF00263 Bacterial type II and III secretion system protein 218 377 4.6E-23 T 09-03-2017 IPR004846 Type II/III secretion system GO:0009306 L21SP3_RS05235 430de11a71e98f35afe88101b8f863f6 286 Pfam PF02517 CAAX protease self-immunity 183 269 1.2E-14 T 09-03-2017 IPR003675 CAAX amino terminal protease GO:0016020 L21SP3_RS11235 8699b02bc32f9158ecd60fd9746669d4 616 Pfam PF16586 Domain of unknown function (DUF5060) 39 121 1.5E-18 T 09-03-2017 IPR032260 Domain of unknown function DUF5060 L21SP3_RS08885 5ff96bb7153af41703a2243308920a01 374 Pfam PF07907 YibE/F-like protein 123 361 1.1E-74 T 09-03-2017 IPR012507 YibE/F-like L21SP3_RS09485 e3f72bb5a9f74d45d78cf761d5c23623 144 Pfam PF13488 Glycine zipper 31 75 2.4E-8 T 09-03-2017 L21SP3_RS03860 bd7fe3105a3ab8522014c89f224438c9 570 Pfam PF08305 NPCBM/NEW2 domain 427 536 4.1E-5 T 09-03-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module L21SP3_RS11175 ded60bbe0493cfb632bce7943fdf3bbf 139 Pfam PF08899 Domain of unknown function (DUF1844) 45 115 1.2E-16 T 09-03-2017 IPR014995 Protein of unknown function DUF1844 L21SP3_RS01395 7b8ef36b3399c3451fbdaf0b4c2a097e 275 Pfam PF04085 rod shape-determining protein MreC 124 264 6.8E-23 T 09-03-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 L21SP3_RS00610 97cd2e83942c7b24afb4bdca96b0a724 200 SUPERFAMILY SSF58104 52 168 1.09E-6 T 09-03-2017 L21SP3_RS10970 8f0718d41e83aaa6d7b5309de6413a93 256 Pfam PF07796 Protein of unknown function (DUF1638) 45 222 1.5E-36 T 09-03-2017 IPR012437 Domain of unknown function DUF1638 L21SP3_RS01350 d8ed0a2e3da2eddcf4446e108ac50f18 437 Pfam PF02687 FtsX-like permease family 295 430 7.2E-10 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020