locus-tag	class	description
PSTA_RS00035	COG3546	catalase activity
PSTA_RS00050	COG0295	cytidine deaminase activity
PSTA_RS00055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PSTA_RS00060	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PSTA_RS00085	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PSTA_RS00115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PSTA_RS00135	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS00165	COG0347	Belongs to the P(II) protein family
PSTA_RS00170	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PSTA_RS00195	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
PSTA_RS00205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PSTA_RS00225	COG1199	ATP-dependent helicase activity
PSTA_RS00335	COG1229	Formylmethanofuran dehydrogenase subunit A
PSTA_RS00355	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PSTA_RS00410	COG4232	protein-disulfide reductase activity
PSTA_RS00415	COG0138	bifunctional purine biosynthesis protein purh
PSTA_RS00465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PSTA_RS00495	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PSTA_RS00500	COG0515	serine threonine protein kinase
PSTA_RS00500	COG2815	serine threonine protein kinase
PSTA_RS00515	COG0575	Belongs to the CDS family
PSTA_RS00520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PSTA_RS00525	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PSTA_RS00550	COG0322	excinuclease ABC activity
PSTA_RS00555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PSTA_RS00560	COG4864	UPF0365 protein
PSTA_RS00570	COG2084	Dehydrogenase
PSTA_RS00595	COG2326	polyphosphate kinase activity
PSTA_RS00600	COG0363	glucosamine-6-phosphate deaminase activity
PSTA_RS00605	COG1774	PSP1 C-terminal conserved region
PSTA_RS00615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PSTA_RS00620	COG0477	Major facilitator Superfamily
PSTA_RS00685	COG0534	Mate efflux family protein
PSTA_RS00690	COG2088	sporulation resulting in formation of a cellular spore
PSTA_RS00695	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PSTA_RS00745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PSTA_RS00785	COG0562	UDP-galactopyranose mutase
PSTA_RS00805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PSTA_RS00805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PSTA_RS00815	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
PSTA_RS00840	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PSTA_RS00845	COG0504	CTP synthase activity
PSTA_RS00860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PSTA_RS00870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PSTA_RS00925	COG0142	geranyltranstransferase activity
PSTA_RS00945	COG4566	intracellular signal transduction
PSTA_RS00950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PSTA_RS00955	COG0745	RESPONSE REGULATOR receiver
PSTA_RS01000	COG3119	arylsulfatase activity
PSTA_RS01045	COG0583	DNA-binding transcription factor activity
PSTA_RS01050	COG0067	glutamate synthase
PSTA_RS01050	COG0070	glutamate synthase
PSTA_RS01050	COG0069	glutamate synthase activity
PSTA_RS01055	COG0493	'glutamate synthase
PSTA_RS01080	COG1970	mechanosensitive ion channel activity
PSTA_RS01085	COG1132	(ABC) transporter
PSTA_RS01100	COG0018	arginyl-trna synthetase
PSTA_RS01110	COG0640	Transcriptional regulator
PSTA_RS01120	COG4166	transmembrane transport
PSTA_RS01125	COG0601	transmembrane transport
PSTA_RS01130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSTA_RS01135	COG0444	Belongs to the ABC transporter superfamily
PSTA_RS01140	COG4608	Belongs to the ABC transporter superfamily
PSTA_RS01165	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PSTA_RS01175	COG2409	Drug exporters of the RND superfamily
PSTA_RS01180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSTA_RS01185	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PSTA_RS01240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PSTA_RS01245	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
PSTA_RS01260	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PSTA_RS01265	COG2814	Major facilitator Superfamily
PSTA_RS01270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PSTA_RS01275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PSTA_RS01300	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PSTA_RS01305	COG0456	acetyltransferase
PSTA_RS01305	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PSTA_RS01315	COG2165	general secretion pathway protein
PSTA_RS01320	COG0515	serine threonine protein kinase
PSTA_RS01320	COG2815	serine threonine protein kinase
PSTA_RS01405	COG0515	serine threonine protein kinase
PSTA_RS01405	COG0457	Tetratricopeptide repeat
PSTA_RS01430	COG3604	Transcriptional regulator
PSTA_RS01580	COG1505	serine-type exopeptidase activity
PSTA_RS01665	COG0205	6-phosphofructokinase activity
PSTA_RS01685	COG0175	sulfate reduction
PSTA_RS01690	COG1959	2 iron, 2 sulfur cluster binding
PSTA_RS01695	COG0134	indole-3-glycerol-phosphate synthase activity
PSTA_RS01710	COG1505	serine-type exopeptidase activity
PSTA_RS01775	COG0612	Peptidase, M16
PSTA_RS01805	COG0430	RNA-3'-phosphate cyclase activity
PSTA_RS01820	COG4650	regulator
PSTA_RS01825	COG3552	Protein containing von Willebrand factor type A (VWA) domain
PSTA_RS01835	COG0714	Associated with various cellular activities
PSTA_RS01850	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PSTA_RS01855	COG0539	negative regulation of cytoplasmic translation
PSTA_RS01865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PSTA_RS01895	COG0072	phenylalanine-tRNA ligase activity
PSTA_RS01900	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PSTA_RS01905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PSTA_RS01910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PSTA_RS01920	COG0165	Argininosuccinate lyase
PSTA_RS01930	COG2204	response regulator
PSTA_RS01940	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PSTA_RS01960	COG1192	Involved in chromosome partitioning
PSTA_RS01970	COG3119	arylsulfatase activity
PSTA_RS02010	COG1899	peptidyl-lysine modification to peptidyl-hypusine
PSTA_RS02040	COG3540	Alkaline phosphatase
PSTA_RS02260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PSTA_RS02265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PSTA_RS02290	COG1331	Highly conserved protein containing a thioredoxin domain
PSTA_RS02315	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PSTA_RS02325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PSTA_RS02330	COG1136	(ABC) transporter
PSTA_RS02365	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PSTA_RS02385	COG2815	serine threonine protein kinase
PSTA_RS02385	COG0515	serine threonine protein kinase
PSTA_RS02390	COG1716	ATPase activity
PSTA_RS02405	COG4191	Histidine kinase
PSTA_RS02410	COG2204	response regulator
PSTA_RS02415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PSTA_RS02420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PSTA_RS02425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PSTA_RS02450	COG3253	May function as heme-dependent peroxidase
PSTA_RS02460	COG3046	protein related to deoxyribodipyrimidine photolyase
PSTA_RS02480	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
PSTA_RS02495	COG2072	flavoprotein involved in K transport
PSTA_RS02520	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PSTA_RS02535	COG0156	8-amino-7-oxononanoate synthase activity
PSTA_RS02545	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PSTA_RS02555	COG0105	UTP biosynthetic process
PSTA_RS02575	COG1215	transferase activity, transferring glycosyl groups
PSTA_RS02590	COG0585	pseudouridine synthase activity
PSTA_RS02600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PSTA_RS02610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PSTA_RS02615	COG1459	type II secretion system
PSTA_RS02655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSTA_RS02685	COG0463	Glycosyl transferase, family 2
PSTA_RS02710	COG3409	Peptidoglycan-binding domain 1 protein
PSTA_RS02710	COG0793	Belongs to the peptidase S41A family
PSTA_RS02740	COG1597	lipid kinase activity
PSTA_RS02745	COG2258	MOSC domain
PSTA_RS02775	COG4948	Mandelate Racemase Muconate Lactonizing
PSTA_RS02795	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PSTA_RS02805	COG0662	Cupin 2, conserved barrel domain protein
PSTA_RS02825	COG2094	Belongs to the DNA glycosylase MPG family
PSTA_RS02830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PSTA_RS02835	COG0537	adenosine 5'-monophosphoramidase activity
PSTA_RS02840	COG1064	alcohol dehydrogenase
PSTA_RS02850	COG3693	PFAM glycoside hydrolase, family 10
PSTA_RS02850	COG2382	esterase
PSTA_RS02850	COG3507	Belongs to the glycosyl hydrolase 43 family
PSTA_RS02900	COG0488	(ABC) transporter
PSTA_RS02925	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PSTA_RS02945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PSTA_RS02980	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PSTA_RS02985	COG4208	sulfate ABC transporter
PSTA_RS02990	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PSTA_RS02995	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PSTA_RS03000	COG3604	Transcriptional regulator
PSTA_RS03025	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PSTA_RS03030	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PSTA_RS03035	COG0681	Belongs to the peptidase S26 family
PSTA_RS03040	COG1137	ATPase activity
PSTA_RS03060	COG0673	inositol 2-dehydrogenase activity
PSTA_RS03090	COG1185	polyribonucleotide nucleotidyltransferase activity
PSTA_RS03145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PSTA_RS03150	COG1136	(ABC) transporter
PSTA_RS03155	COG4591	ABC-type transport system involved in lipoprotein release permease component
PSTA_RS03165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PSTA_RS03235	COG0745	RESPONSE REGULATOR receiver
PSTA_RS03280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PSTA_RS03350	COG0574	Belongs to the PEP-utilizing enzyme family
PSTA_RS03350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PSTA_RS03400	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PSTA_RS03420	COG1082	Xylose isomerase domain protein TIM barrel
PSTA_RS03430	COG0673	inositol 2-dehydrogenase activity
PSTA_RS03475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PSTA_RS03505	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
PSTA_RS03515	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PSTA_RS03530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PSTA_RS03535	COG0242	peptide deformylase activity
PSTA_RS03550	COG1994	Peptidase M50
PSTA_RS03560	COG0489	protein tyrosine kinase activity
PSTA_RS03575	COG1007	ATP synthesis coupled electron transport
PSTA_RS03590	COG0713	ATP synthesis coupled electron transport
PSTA_RS03600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSTA_RS03620	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
PSTA_RS03625	COG0649	NAD binding
PSTA_RS03630	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSTA_RS03635	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSTA_RS03640	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSTA_RS03675	COG0657	acetylesterase activity
PSTA_RS03735	COG0202	RNA polymerase activity
PSTA_RS03755	COG1301	dicarboxylic acid transport
PSTA_RS03770	COG0205	6-phosphofructokinase activity
PSTA_RS03785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PSTA_RS03795	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PSTA_RS03815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PSTA_RS03820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PSTA_RS03845	COG1309	transcriptional regulator
PSTA_RS03875	COG3795	YCII-related domain
PSTA_RS03885	COG0114	fumarate hydratase activity
PSTA_RS03900	COG2081	HI0933 family
PSTA_RS03915	COG2379	hydroxypyruvate reductase
PSTA_RS03970	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PSTA_RS03970	COG0674	pyruvate-flavodoxin oxidoreductase activity
PSTA_RS03975	COG1013	pyruvate-flavodoxin oxidoreductase activity
PSTA_RS03995	COG1397	ADP-ribosylglycohydrolase
PSTA_RS04025	COG1131	(ABC) transporter
PSTA_RS04035	COG3437	response regulator, receiver
PSTA_RS04050	COG0024	Methionine aminopeptidase
PSTA_RS04055	COG0616	signal peptide processing
PSTA_RS04070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PSTA_RS04070	COG4651	solute:proton antiporter activity
PSTA_RS04075	COG3685	Protein conserved in bacteria
PSTA_RS04105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PSTA_RS04125	COG0542	response to heat
PSTA_RS04140	COG0443	Heat shock 70 kDa protein
PSTA_RS04145	COG1605	Chorismate mutase
PSTA_RS04145	COG0077	Prephenate dehydratase
PSTA_RS04150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PSTA_RS04160	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PSTA_RS04165	COG0517	IMP dehydrogenase activity
PSTA_RS04165	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PSTA_RS04170	COG0191	fructose-bisphosphate aldolase activity
PSTA_RS04235	COG0653	protein targeting
PSTA_RS04260	COG2009	succinate dehydrogenase
PSTA_RS04265	COG1053	succinate dehydrogenase
PSTA_RS04270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PSTA_RS04285	COG5434	Belongs to the glycosyl hydrolase 28 family
PSTA_RS04290	COG1012	belongs to the aldehyde dehydrogenase family
PSTA_RS04310	COG0386	Belongs to the glutathione peroxidase family
PSTA_RS04335	COG0493	'glutamate synthase
PSTA_RS04335	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
PSTA_RS04345	COG1562	ergosterol biosynthetic process
PSTA_RS04355	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PSTA_RS04390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PSTA_RS04400	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
PSTA_RS04425	COG3119	arylsulfatase activity
PSTA_RS04475	COG0714	Associated with various cellular activities
PSTA_RS04485	COG0564	pseudouridine synthase activity
PSTA_RS04490	COG1331	Highly conserved protein containing a thioredoxin domain
PSTA_RS04495	COG4221	oxidoreductase activity
PSTA_RS04540	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
PSTA_RS04550	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PSTA_RS04580	COG4956	integral membrane protein (PIN domain superfamily)
PSTA_RS04590	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PSTA_RS04595	COG1132	(ABC) transporter
PSTA_RS04600	COG2204	response regulator
PSTA_RS04620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PSTA_RS04625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PSTA_RS04655	COG1082	Xylose isomerase domain protein TIM barrel
PSTA_RS04660	COG0246	Mannitol dehydrogenase
PSTA_RS04665	COG1063	alcohol dehydrogenase
PSTA_RS04670	COG0667	Aldo Keto reductase
PSTA_RS04675	COG1609	Transcriptional regulator
PSTA_RS04675	COG2207	Transcriptional regulator
PSTA_RS04690	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PSTA_RS04720	COG0052	Belongs to the universal ribosomal protein uS2 family
PSTA_RS04730	COG0528	UMP kinase activity
PSTA_RS04735	COG0233	cytoplasmic translational termination
PSTA_RS04740	COG0584	glycerophosphoryl diester phosphodiesterase
PSTA_RS04785	COG0848	biopolymer transport protein
PSTA_RS04795	COG0811	peptide transport
PSTA_RS04825	COG0012	GTP binding
PSTA_RS04875	COG0473	3-isopropylmalate dehydrogenase activity
PSTA_RS04880	COG1663	tetraacyldisaccharide 4'-kinase activity
PSTA_RS04905	COG0529	Catalyzes the synthesis of activated sulfate
PSTA_RS04925	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PSTA_RS04930	COG1335	isochorismatase
PSTA_RS04945	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS04950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PSTA_RS04955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PSTA_RS04965	COG0284	orotidine-5'-phosphate decarboxylase activity
PSTA_RS05000	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
PSTA_RS05005	COG0297	glycogen (starch) synthase activity
PSTA_RS05015	COG1796	DNA polymerase
PSTA_RS05015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PSTA_RS05020	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PSTA_RS05050	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PSTA_RS05055	COG1872	DUF167
PSTA_RS05070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PSTA_RS05110	COG0640	Transcriptional regulator
PSTA_RS05135	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PSTA_RS05140	COG1104	cysteine desulfurase activity
PSTA_RS05145	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PSTA_RS05155	COG0592	DNA-directed DNA polymerase activity
PSTA_RS05165	COG0187	DNA topoisomerase II activity
PSTA_RS05190	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PSTA_RS05200	COG1611	Belongs to the LOG family
PSTA_RS05205	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS05235	COG0287	Prephenate dehydrogenase
PSTA_RS05240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PSTA_RS05245	COG0047	phosphoribosylformylglycinamidine synthase activity
PSTA_RS05270	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PSTA_RS05280	COG0799	negative regulation of ribosome biogenesis
PSTA_RS05285	COG0758	DNA mediated transformation
PSTA_RS05285	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PSTA_RS05290	COG4566	intracellular signal transduction
PSTA_RS05410	COG3852	Histidine kinase
PSTA_RS05420	COG0445	tRNA wobble uridine modification
PSTA_RS05440	COG4912	Dna alkylation repair
PSTA_RS05445	COG0583	DNA-binding transcription factor activity
PSTA_RS05465	COG0437	4 iron, 4 sulfur cluster binding
PSTA_RS05525	COG0058	SHG alpha-glucan phosphorylase activity
PSTA_RS05545	COG2706	6-phosphogluconolactonase activity
PSTA_RS05595	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
PSTA_RS05720	COG2365	Tyrosine phosphatase family
PSTA_RS05740	COG3119	arylsulfatase activity
PSTA_RS05755	COG0673	inositol 2-dehydrogenase activity
PSTA_RS05765	COG3119	arylsulfatase activity
PSTA_RS05780	COG0646	methionine synthase
PSTA_RS05780	COG1410	methionine synthase
PSTA_RS05800	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PSTA_RS05820	COG4964	Belongs to the GSP D family
PSTA_RS05890	COG5609	conserved protein (DUF2294)
PSTA_RS05910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PSTA_RS05980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSTA_RS06015	COG1136	(ABC) transporter
PSTA_RS06020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSTA_RS06100	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PSTA_RS06110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PSTA_RS06155	COG0006	proline dipeptidase activity
PSTA_RS06170	COG3938	Belongs to the proline racemase family
PSTA_RS06175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSTA_RS06210	COG1595	DNA-templated transcription, initiation
PSTA_RS06215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PSTA_RS06280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PSTA_RS06280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PSTA_RS06350	COG3119	arylsulfatase activity
PSTA_RS06375	COG0438	transferase activity, transferring glycosyl groups
PSTA_RS06400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PSTA_RS06410	COG1196	nuclear chromosome segregation
PSTA_RS06415	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PSTA_RS06420	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
PSTA_RS06430	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PSTA_RS06450	COG0822	iron-sulfur transferase activity
PSTA_RS06455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PSTA_RS06470	COG1131	(ABC) transporter
PSTA_RS06480	COG0657	acetylesterase activity
PSTA_RS06485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PSTA_RS06490	COG3119	arylsulfatase activity
PSTA_RS06495	COG3119	arylsulfatase activity
PSTA_RS06505	COG2738	Putative neutral zinc metallopeptidase
PSTA_RS06515	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSTA_RS06535	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PSTA_RS06570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PSTA_RS06600	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PSTA_RS06605	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PSTA_RS06625	COG2226	methyltransferase
PSTA_RS06635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PSTA_RS06690	COG0513	Belongs to the DEAD box helicase family
PSTA_RS06730	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PSTA_RS06735	COG2814	Major facilitator Superfamily
PSTA_RS06740	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PSTA_RS06770	COG1858	cytochrome C peroxidase
PSTA_RS06790	COG2195	Cleaves the N-terminal amino acid of tripeptides
PSTA_RS06825	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PSTA_RS06830	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PSTA_RS06850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PSTA_RS06925	COG0640	Transcriptional regulator
PSTA_RS06935	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PSTA_RS06935	COG0515	serine threonine protein kinase
PSTA_RS06940	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PSTA_RS06945	COG0588	phosphoglycerate mutase activity
PSTA_RS06950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PSTA_RS06965	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PSTA_RS06970	COG0367	asparagine synthase
PSTA_RS07030	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PSTA_RS07035	COG0673	inositol 2-dehydrogenase activity
PSTA_RS07040	COG0110	maltose O-acetyltransferase activity
PSTA_RS07055	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PSTA_RS07060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PSTA_RS07080	COG0438	transferase activity, transferring glycosyl groups
PSTA_RS07110	COG2186	Transcriptional regulator
PSTA_RS07115	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PSTA_RS07140	COG3119	arylsulfatase activity
PSTA_RS07155	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PSTA_RS07165	COG0501	Belongs to the peptidase M48B family
PSTA_RS07170	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PSTA_RS07195	COG0038	chloride channel
PSTA_RS07235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PSTA_RS07245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PSTA_RS07250	COG2154	pterin-4-alpha-carbinolamine dehydratase
PSTA_RS07290	COG1053	succinate dehydrogenase
PSTA_RS07320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PSTA_RS07360	COG0724	RNA recognition motif
PSTA_RS07390	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
PSTA_RS07430	COG1410	methionine synthase
PSTA_RS07430	COG0646	methionine synthase
PSTA_RS07460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PSTA_RS07520	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PSTA_RS07555	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PSTA_RS07580	COG1668	transmembrane transport
PSTA_RS07585	COG4555	ABC transporter
PSTA_RS07595	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PSTA_RS07600	COG0745	RESPONSE REGULATOR receiver
PSTA_RS07610	COG0714	Associated with various cellular activities
PSTA_RS07665	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PSTA_RS07670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PSTA_RS07695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PSTA_RS07715	COG0714	Associated with various cellular activities
PSTA_RS07730	COG0604	alcohol dehydrogenase
PSTA_RS07755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSTA_RS07760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PSTA_RS07765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSTA_RS07770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PSTA_RS07790	COG0589	response to stress
PSTA_RS07795	COG2204	response regulator
PSTA_RS07800	COG3852	Histidine kinase
PSTA_RS07805	COG1201	RNA secondary structure unwinding
PSTA_RS07815	COG2261	transglycosylase associated protein
PSTA_RS07845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PSTA_RS07850	COG3118	belongs to the thioredoxin family
PSTA_RS07880	COG0431	NADPH-dependent FMN reductase
PSTA_RS07885	COG0783	Belongs to the Dps family
PSTA_RS07895	COG1741	Belongs to the pirin family
PSTA_RS07935	COG0495	leucyl-tRNA aminoacylation
PSTA_RS07940	COG0024	Methionine aminopeptidase
PSTA_RS07950	COG1234	tRNA 3'-trailer cleavage
PSTA_RS07960	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PSTA_RS07970	COG1231	oxidoreductase activity
PSTA_RS07975	COG1090	epimerase
PSTA_RS07980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PSTA_RS08005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PSTA_RS08015	COG1032	radical SAM domain protein
PSTA_RS08025	COG0438	transferase activity, transferring glycosyl groups
PSTA_RS08080	COG1073	alpha beta
PSTA_RS08085	COG1104	cysteine desulfurase activity
PSTA_RS08155	COG2814	Major facilitator Superfamily
PSTA_RS08160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PSTA_RS08175	COG1402	creatininase
PSTA_RS08180	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PSTA_RS08255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PSTA_RS08265	COG0456	acetyltransferase
PSTA_RS08270	COG0612	Peptidase, M16
PSTA_RS08275	COG5609	conserved protein (DUF2294)
PSTA_RS08290	COG2201	protein-glutamate methylesterase activity
PSTA_RS08325	COG1047	Peptidyl-prolyl cis-trans
PSTA_RS08365	COG2169	Transcriptional regulator
PSTA_RS08365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PSTA_RS08380	COG2022	thiamine diphosphate biosynthetic process
PSTA_RS08410	COG1215	transferase activity, transferring glycosyl groups
PSTA_RS08445	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PSTA_RS08450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PSTA_RS08455	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS08460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PSTA_RS08475	COG1136	(ABC) transporter
PSTA_RS08485	COG2211	Major facilitator Superfamily
PSTA_RS08495	COG1136	(ABC) transporter
PSTA_RS08500	COG0577	efflux transmembrane transporter activity
PSTA_RS08500	COG1136	(ABC) transporter
PSTA_RS08505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PSTA_RS08515	COG1657	PFAM Prenyltransferase squalene oxidase
PSTA_RS08520	COG1309	transcriptional regulator
PSTA_RS08540	COG0107	imidazoleglycerol-phosphate synthase activity
PSTA_RS08565	COG1381	Involved in DNA repair and RecF pathway recombination
PSTA_RS08580	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PSTA_RS08605	COG0596	Alpha beta hydrolase
PSTA_RS08615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PSTA_RS08630	COG0544	peptidyl-prolyl cis-trans isomerase activity
PSTA_RS08635	COG0740	serine-type endopeptidase activity
PSTA_RS08640	COG0740	serine-type endopeptidase activity
PSTA_RS08655	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PSTA_RS08670	COG1131	(ABC) transporter
PSTA_RS08695	COG3386	PFAM SMP-30 Gluconolaconase
PSTA_RS08705	COG2239	Acts as a magnesium transporter
PSTA_RS08710	COG4581	dead DEAH box helicase
PSTA_RS08720	COG0028	Belongs to the TPP enzyme family
PSTA_RS08725	COG3386	PFAM SMP-30 Gluconolaconase
PSTA_RS08730	COG2721	sulfolactate sulfo-lyase activity
PSTA_RS08735	COG0590	tRNA wobble adenosine to inosine editing
PSTA_RS08760	COG2226	methyltransferase
PSTA_RS08765	COG0163	prenyltransferase activity
PSTA_RS08775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PSTA_RS08805	COG0515	serine threonine protein kinase
PSTA_RS08900	COG1902	pentaerythritol trinitrate reductase activity
PSTA_RS08920	COG3119	arylsulfatase activity
PSTA_RS09070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS09080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PSTA_RS09085	COG1012	belongs to the aldehyde dehydrogenase family
PSTA_RS09090	COG1166	arginine decarboxylase activity
PSTA_RS09095	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PSTA_RS09140	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PSTA_RS09185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PSTA_RS09185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PSTA_RS09205	COG0352	thiamine-phosphate diphosphorylase activity
PSTA_RS09220	COG0542	response to heat
PSTA_RS09230	COG3781	membrane
PSTA_RS09285	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PSTA_RS09290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PSTA_RS09370	COG0436	Aminotransferase
PSTA_RS09380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PSTA_RS09390	COG1063	alcohol dehydrogenase
PSTA_RS09420	COG3273	potassium ion transport
PSTA_RS09420	COG0471	metal ion transport
PSTA_RS09425	COG0673	inositol 2-dehydrogenase activity
PSTA_RS09430	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PSTA_RS09445	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PSTA_RS09450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PSTA_RS09480	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PSTA_RS09490	COG1176	ABC-type spermidine putrescine transport system, permease component I
PSTA_RS09545	COG0424	maF-like protein
PSTA_RS09550	COG0123	including yeast histone deacetylase and acetoin utilization protein
PSTA_RS09555	COG1643	Atp-dependent helicase
PSTA_RS09565	COG0443	Heat shock 70 kDa protein
PSTA_RS09590	COG0354	folic acid binding
PSTA_RS09630	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PSTA_RS09665	COG1573	uracil-dna glycosylase
PSTA_RS09670	COG1160	GTP binding
PSTA_RS09675	COG0686	Belongs to the AlaDH PNT family
PSTA_RS09680	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PSTA_RS09740	COG0811	peptide transport
PSTA_RS09775	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS09820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PSTA_RS09825	COG0135	phosphoribosylanthranilate isomerase activity
PSTA_RS09835	COG3267	Type II secretory pathway component ExeA
PSTA_RS09835	COG3409	Peptidoglycan-binding domain 1 protein
PSTA_RS09855	COG1216	Glycosyl transferase, family 2
PSTA_RS09860	COG0310	cobalt ion transport
PSTA_RS09895	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PSTA_RS09900	COG1215	transferase activity, transferring glycosyl groups
PSTA_RS09905	COG0463	Glycosyl transferase, family 2
PSTA_RS09920	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PSTA_RS09930	COG0788	formyltetrahydrofolate deformylase activity
PSTA_RS09940	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS09945	COG2895	sulfate adenylyltransferase (ATP) activity
PSTA_RS09945	COG0529	Catalyzes the synthesis of activated sulfate
PSTA_RS09950	COG0175	sulfate reduction
PSTA_RS09980	COG1968	undecaprenyl-diphosphatase activity
PSTA_RS09990	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PSTA_RS09990	COG1793	dna ligase
PSTA_RS10010	COG2363	Small membrane protein
PSTA_RS10015	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PSTA_RS10020	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PSTA_RS10045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PSTA_RS10085	COG1054	Belongs to the UPF0176 family
PSTA_RS10090	COG0617	tRNA 3'-terminal CCA addition
PSTA_RS10130	COG0840	transmembrane signaling receptor activity
PSTA_RS10135	COG2198	Histidine kinase
PSTA_RS10135	COG0784	Response regulator, receiver
PSTA_RS10135	COG0643	Histidine kinase
PSTA_RS10190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PSTA_RS10205	COG0443	Heat shock 70 kDa protein
PSTA_RS10230	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PSTA_RS10280	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PSTA_RS10285	COG2378	regulation of single-species biofilm formation
PSTA_RS10335	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PSTA_RS10345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PSTA_RS10345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PSTA_RS10375	COG0475	glutathione-regulated potassium exporter activity
PSTA_RS10395	COG1216	Glycosyl transferase, family 2
PSTA_RS10430	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PSTA_RS10445	COG0714	Associated with various cellular activities
PSTA_RS10460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PSTA_RS10475	COG1127	ABC transporter
PSTA_RS10480	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PSTA_RS10485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PSTA_RS10535	COG0523	cobalamin synthesis protein
PSTA_RS10575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PSTA_RS10585	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PSTA_RS10585	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PSTA_RS10590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PSTA_RS10595	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PSTA_RS10605	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PSTA_RS10640	COG0363	glucosamine-6-phosphate deaminase activity
PSTA_RS10665	COG0561	phosphatase activity
PSTA_RS10670	COG0438	transferase activity, transferring glycosyl groups
PSTA_RS10685	COG0124	histidyl-tRNA synthetase
PSTA_RS10730	COG0247	lactate metabolic process
PSTA_RS10755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS10760	COG0517	IMP dehydrogenase activity
PSTA_RS10810	COG2186	Transcriptional regulator
PSTA_RS10815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PSTA_RS10870	COG1397	ADP-ribosylglycohydrolase
PSTA_RS10910	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PSTA_RS10920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PSTA_RS10925	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PSTA_RS10940	COG2766	serine protein kinase
PSTA_RS10945	COG2718	Belongs to the UPF0229 family
PSTA_RS10950	COG2719	SpoVR family
PSTA_RS10975	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PSTA_RS10985	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PSTA_RS11075	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PSTA_RS11080	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PSTA_RS11085	COG0228	four-way junction DNA binding
PSTA_RS11090	COG0336	Belongs to the RNA methyltransferase TrmD family
PSTA_RS11095	COG0335	large ribosomal subunit rRNA binding
PSTA_RS11100	COG0792	nuclease activity
PSTA_RS11125	COG1074	ATP-dependent DNA helicase activity
PSTA_RS11135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PSTA_RS11145	COG5183	chlorophyll binding
PSTA_RS11145	COG2133	pyrroloquinoline quinone binding
PSTA_RS11155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PSTA_RS11195	COG1611	Belongs to the LOG family
PSTA_RS11225	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PSTA_RS11250	COG0601	transmembrane transport
PSTA_RS11255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSTA_RS11260	COG4172	Belongs to the ABC transporter superfamily
PSTA_RS11280	COG0673	inositol 2-dehydrogenase activity
PSTA_RS11325	COG1803	Methylglyoxal synthase
PSTA_RS11370	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS11385	COG0714	Associated with various cellular activities
PSTA_RS11435	COG1595	DNA-templated transcription, initiation
PSTA_RS11445	COG2226	methyltransferase
PSTA_RS11455	COG0473	3-isopropylmalate dehydrogenase activity
PSTA_RS11465	COG0673	inositol 2-dehydrogenase activity
PSTA_RS11480	COG0302	gtp cyclohydrolase
PSTA_RS11495	COG0277	FAD linked oxidase domain protein
PSTA_RS11495	COG0247	lactate metabolic process
PSTA_RS11505	COG0314	molybdopterin synthase activity
PSTA_RS11510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PSTA_RS11520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PSTA_RS11540	COG0517	IMP dehydrogenase activity
PSTA_RS11540	COG0617	tRNA 3'-terminal CCA addition
PSTA_RS11540	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PSTA_RS11550	COG1090	epimerase
PSTA_RS11570	COG0318	PFAM AMP-dependent synthetase and ligase
PSTA_RS11585	COG0181	hydroxymethylbilane synthase activity
PSTA_RS11590	COG4786	Flagellar basal body rod
PSTA_RS11595	COG4786	Flagellar basal body rod
PSTA_RS11605	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PSTA_RS11610	COG1706	bacterial-type flagellum-dependent cell motility
PSTA_RS11630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PSTA_RS11635	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PSTA_RS11640	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PSTA_RS11665	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
PSTA_RS11680	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PSTA_RS11735	COG1131	(ABC) transporter
PSTA_RS11740	COG0285	dihydrofolate synthase activity
PSTA_RS11755	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PSTA_RS11755	COG1918	ferrous iron import across plasma membrane
PSTA_RS11760	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PSTA_RS11760	COG1918	ferrous iron import across plasma membrane
PSTA_RS11780	COG1012	belongs to the aldehyde dehydrogenase family
PSTA_RS11790	COG1509	lysine 2,3-aminomutase activity
PSTA_RS11795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PSTA_RS11800	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
PSTA_RS11810	COG0357	Ribosomal RNA small subunit methyltransferase G
PSTA_RS11820	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PSTA_RS11825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PSTA_RS11835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PSTA_RS11850	COG0539	negative regulation of cytoplasmic translation
PSTA_RS11850	COG2183	response to ionizing radiation
PSTA_RS11860	COG0346	lactoylglutathione lyase activity
PSTA_RS11895	COG0488	(ABC) transporter
PSTA_RS11900	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PSTA_RS11920	COG0564	pseudouridine synthase activity
PSTA_RS11950	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PSTA_RS11955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PSTA_RS11965	COG1530	ribonuclease E activity
PSTA_RS11970	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PSTA_RS11980	COG4191	Histidine kinase
PSTA_RS11985	COG0649	NAD binding
PSTA_RS11990	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSTA_RS11995	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSTA_RS12010	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PSTA_RS12020	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PSTA_RS12025	COG0183	Belongs to the thiolase family
PSTA_RS12030	COG0667	Aldo Keto reductase
PSTA_RS12055	COG0494	nUDIX hydrolase
PSTA_RS12060	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PSTA_RS12065	COG2204	response regulator
PSTA_RS12080	COG0596	Alpha beta hydrolase
PSTA_RS12110	COG0811	peptide transport
PSTA_RS12115	COG0848	biopolymer transport protein
PSTA_RS12125	COG0602	queuosine metabolic process
PSTA_RS12130	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PSTA_RS12135	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PSTA_RS12150	COG0534	Mate efflux family protein
PSTA_RS12160	COG2957	Belongs to the agmatine deiminase family
PSTA_RS12180	COG0673	inositol 2-dehydrogenase activity
PSTA_RS12190	COG0205	6-phosphofructokinase activity
PSTA_RS12200	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PSTA_RS12205	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS12210	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PSTA_RS12230	COG1940	carbohydrate kinase activity
PSTA_RS12235	COG0129	dihydroxy-acid dehydratase activity
PSTA_RS12255	COG0328	RNA-DNA hybrid ribonuclease activity
PSTA_RS12310	COG1674	ftsk spoiiie
PSTA_RS12315	COG3541	Predicted nucleotidyltransferase
PSTA_RS12370	COG4977	sequence-specific DNA binding
PSTA_RS12380	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PSTA_RS12395	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PSTA_RS12400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PSTA_RS12405	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
PSTA_RS12410	COG1418	mRNA catabolic process
PSTA_RS12420	COG4555	ABC transporter
PSTA_RS12440	COG1480	7TM receptor with intracellular HD hydrolase
PSTA_RS12445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PSTA_RS12475	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSTA_RS12480	COG1879	ABC-type sugar transport system periplasmic component
PSTA_RS12495	COG3119	arylsulfatase activity
PSTA_RS12510	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PSTA_RS12515	COG0049	tRNA binding
PSTA_RS12520	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PSTA_RS12525	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PSTA_RS12530	COG0085	RNA polymerase activity
PSTA_RS12535	COG0222	ribosome binding
PSTA_RS12540	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PSTA_RS12545	COG0081	regulation of translation
PSTA_RS12550	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PSTA_RS12555	COG0250	Participates in transcription elongation, termination and antitermination
PSTA_RS12570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PSTA_RS12595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PSTA_RS12710	COG1022	Amp-dependent synthetase and ligase
PSTA_RS12720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PSTA_RS12735	COG0698	ribose 5-phosphate isomerase
PSTA_RS12780	COG3693	PFAM glycoside hydrolase, family 10
PSTA_RS12780	COG2382	esterase
PSTA_RS12785	COG0704	Plays a role in the regulation of phosphate uptake
PSTA_RS12790	COG0745	RESPONSE REGULATOR receiver
PSTA_RS12800	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PSTA_RS12805	COG0051	transcription antitermination factor activity, RNA binding
PSTA_RS12810	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PSTA_RS12815	COG0088	Forms part of the polypeptide exit tunnel
PSTA_RS12820	COG0089	rRNA binding
PSTA_RS12825	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PSTA_RS12830	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PSTA_RS12835	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PSTA_RS12840	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PSTA_RS12845	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PSTA_RS12850	COG0255	Belongs to the universal ribosomal protein uL29 family
PSTA_RS12855	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PSTA_RS12860	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PSTA_RS12865	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PSTA_RS12870	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PSTA_RS12875	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PSTA_RS12880	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PSTA_RS12885	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PSTA_RS12890	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PSTA_RS12895	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PSTA_RS12900	COG0200	Binds to the 23S rRNA
PSTA_RS12910	COG0563	adenylate kinase activity
PSTA_RS12915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PSTA_RS12920	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PSTA_RS12925	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PSTA_RS12930	COG0202	RNA polymerase activity
PSTA_RS12935	COG0203	ribosomal protein L17
PSTA_RS12970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PSTA_RS12980	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS13015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS13025	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSTA_RS13040	COG0247	lactate metabolic process
PSTA_RS13050	COG0277	FAD linked oxidase domain protein
PSTA_RS13055	COG0579	oxidoreductase
PSTA_RS13065	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PSTA_RS13085	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
PSTA_RS13090	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PSTA_RS13100	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PSTA_RS13120	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PSTA_RS13125	COG0305	Participates in initiation and elongation during chromosome replication
PSTA_RS13130	COG0359	binds to the 23S rRNA
PSTA_RS13135	COG0629	single-stranded DNA binding
PSTA_RS13140	COG0360	Binds together with S18 to 16S ribosomal RNA
PSTA_RS13145	COG0193	aminoacyl-tRNA hydrolase activity
PSTA_RS13150	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PSTA_RS13165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PSTA_RS13170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PSTA_RS13175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PSTA_RS13180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PSTA_RS13185	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PSTA_RS13190	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PSTA_RS13200	COG3119	arylsulfatase activity
PSTA_RS13205	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PSTA_RS13250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PSTA_RS13255	COG0358	DNA primase activity
PSTA_RS13290	COG0714	Associated with various cellular activities
PSTA_RS13310	COG0784	Response regulator, receiver
PSTA_RS13310	COG5002	protein histidine kinase activity
PSTA_RS13330	COG0424	maF-like protein
PSTA_RS13335	COG0564	pseudouridine synthase activity
PSTA_RS13405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS13410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS13415	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PSTA_RS13490	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PSTA_RS13590	COG1959	2 iron, 2 sulfur cluster binding
PSTA_RS13595	COG0363	glucosamine-6-phosphate deaminase activity
PSTA_RS13655	COG2815	serine threonine protein kinase
PSTA_RS13655	COG0515	serine threonine protein kinase
PSTA_RS13680	COG1454	alcohol dehydrogenase
PSTA_RS13700	COG0606	chelatase, subunit chli
PSTA_RS13715	COG0471	metal ion transport
PSTA_RS13745	COG0811	peptide transport
PSTA_RS13800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PSTA_RS13810	COG0573	inorganic phosphate transmembrane transporter activity
PSTA_RS13815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PSTA_RS13825	COG1674	ftsk spoiiie
PSTA_RS13825	COG4980	gas vesicle protein
PSTA_RS13830	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PSTA_RS13840	COG0113	porphobilinogen synthase activity
PSTA_RS13845	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PSTA_RS13855	COG0519	Catalyzes the synthesis of GMP from XMP
PSTA_RS13855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PSTA_RS13860	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PSTA_RS13895	COG0673	inositol 2-dehydrogenase activity
PSTA_RS13945	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PSTA_RS13965	COG0693	protein deglycase activity
PSTA_RS13970	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PSTA_RS13980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PSTA_RS13990	COG0564	pseudouridine synthase activity
PSTA_RS13995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PSTA_RS14005	COG1305	Transglutaminase-like
PSTA_RS14020	COG2308	Evidence 4 Homologs of previously reported genes of
PSTA_RS14025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PSTA_RS14055	COG0747	negative chemotaxis
PSTA_RS14060	COG0601	transmembrane transport
PSTA_RS14065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSTA_RS14070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PSTA_RS14070	COG0426	domain, Protein
PSTA_RS14085	COG0148	phosphopyruvate hydratase activity
PSTA_RS14110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PSTA_RS14115	COG0006	proline dipeptidase activity
PSTA_RS14125	COG1966	Carbon starvation protein
PSTA_RS14165	COG1088	dTDP-glucose 4,6-dehydratase activity
PSTA_RS14175	COG0811	peptide transport
PSTA_RS14180	COG0848	biopolymer transport protein
PSTA_RS14265	COG5564	TIM-barrel signal transduction protein
PSTA_RS14270	COG3119	arylsulfatase activity
PSTA_RS14300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PSTA_RS14305	COG0166	Belongs to the GPI family
PSTA_RS14315	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
PSTA_RS14355	COG0714	Associated with various cellular activities
PSTA_RS14380	COG2322	membrane
PSTA_RS14405	COG1845	cytochrome c oxidase, subunit III
PSTA_RS14410	COG0109	protoheme IX farnesyltransferase activity
PSTA_RS14420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PSTA_RS14430	COG2010	Cytochrome c
PSTA_RS14455	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PSTA_RS14465	COG0151	Belongs to the GarS family
PSTA_RS14505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PSTA_RS14515	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PSTA_RS14520	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PSTA_RS14560	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PSTA_RS14565	COG0275	rRNA processing
PSTA_RS14570	COG0438	transferase activity, transferring glycosyl groups
PSTA_RS14580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSTA_RS14585	COG1136	(ABC) transporter
PSTA_RS14595	COG0577	efflux transmembrane transporter activity
PSTA_RS14600	COG0514	ATP-dependent DNA helicase (RecQ)
PSTA_RS14605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PSTA_RS14610	COG1162	GTPase activity
PSTA_RS14615	COG1104	cysteine desulfurase activity
PSTA_RS14620	COG0316	Belongs to the HesB IscA family
PSTA_RS14635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PSTA_RS14645	COG0657	acetylesterase activity
PSTA_RS14665	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PSTA_RS14680	COG0347	Belongs to the P(II) protein family
PSTA_RS14810	COG0826	peptidase U32
PSTA_RS14815	COG1070	Carbohydrate kinase
PSTA_RS14820	COG0673	inositol 2-dehydrogenase activity
PSTA_RS14865	COG1448	Aminotransferase
PSTA_RS14880	COG0459	protein refolding
PSTA_RS14885	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PSTA_RS14890	COG0459	protein refolding
PSTA_RS14895	COG0484	heat shock protein binding
PSTA_RS14900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PSTA_RS14910	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PSTA_RS14935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PSTA_RS14965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSTA_RS14975	COG2239	Acts as a magnesium transporter
PSTA_RS15045	COG1073	alpha beta
PSTA_RS15115	COG2201	protein-glutamate methylesterase activity
PSTA_RS15120	COG0745	RESPONSE REGULATOR receiver
PSTA_RS15130	COG0835	chemotaxis
PSTA_RS15135	COG0643	Histidine kinase
PSTA_RS15135	COG2198	Histidine kinase
PSTA_RS15140	COG0745	RESPONSE REGULATOR receiver
PSTA_RS15140	COG4191	Histidine kinase
PSTA_RS15140	COG2205	protein histidine kinase activity
PSTA_RS15140	COG2205	protein histidine kinase activity
PSTA_RS15140	COG0745	RESPONSE REGULATOR receiver
PSTA_RS15140	COG4191	Histidine kinase
PSTA_RS15150	COG1007	ATP synthesis coupled electron transport
PSTA_RS15155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PSTA_RS15160	COG3002	Belongs to the UPF0753 family
PSTA_RS15165	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PSTA_RS15215	COG0577	efflux transmembrane transporter activity
PSTA_RS15215	COG1136	(ABC) transporter
PSTA_RS15225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSTA_RS15255	COG2192	nodulation
PSTA_RS15290	COG2321	neutral zinc metallopeptidase
PSTA_RS15295	COG3485	protocatechuate 3,4-dioxygenase
PSTA_RS15325	COG0494	nUDIX hydrolase
PSTA_RS15330	COG0727	PFAM Uncharacterised protein family (UPF0153)
PSTA_RS15345	COG0167	dihydroorotate dehydrogenase activity
PSTA_RS15350	COG0180	Tryptophanyl-tRNA synthetase
PSTA_RS15365	COG1643	Atp-dependent helicase
PSTA_RS15380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PSTA_RS15385	COG1758	RNA polymerase activity
PSTA_RS15390	COG0194	GDP metabolic process
PSTA_RS15395	COG1561	YicC-like family, N-terminal region
PSTA_RS15405	COG0149	triose-phosphate isomerase activity
PSTA_RS15410	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PSTA_RS15420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PSTA_RS15430	COG0315	cyclic pyranopterin monophosphate synthase activity
PSTA_RS15435	COG0142	geranyltranstransferase activity
PSTA_RS15445	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PSTA_RS15460	COG0235	Class ii aldolase
PSTA_RS15465	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PSTA_RS15470	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
PSTA_RS15485	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PSTA_RS15495	COG0713	ATP synthesis coupled electron transport
PSTA_RS15500	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PSTA_RS15525	COG0084	hydrolase, TatD family'
PSTA_RS15530	COG0492	ferredoxin-NADP+ reductase activity
PSTA_RS15535	COG0586	Pfam SNARE associated Golgi protein
PSTA_RS15540	COG2814	Major facilitator Superfamily
PSTA_RS15545	COG0017	Asparaginyl-tRNA synthetase
PSTA_RS15555	COG0372	Belongs to the citrate synthase family
PSTA_RS15560	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PSTA_RS15575	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PSTA_RS15580	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PSTA_RS15585	COG0861	Integral membrane protein TerC family
PSTA_RS15610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PSTA_RS15615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PSTA_RS15640	COG2205	protein histidine kinase activity
PSTA_RS15670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PSTA_RS15680	COG1321	iron dependent repressor
PSTA_RS15685	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
PSTA_RS15690	COG0189	ligase activity
PSTA_RS15695	COG0318	PFAM AMP-dependent synthetase and ligase
PSTA_RS15700	COG1063	alcohol dehydrogenase
PSTA_RS15710	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PSTA_RS15715	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PSTA_RS15725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS15745	COG0300	oxidoreductase activity
PSTA_RS15810	COG0297	glycogen (starch) synthase activity
PSTA_RS15820	COG1449	Belongs to the glycosyl hydrolase 57 family
PSTA_RS15825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PSTA_RS15830	COG1959	2 iron, 2 sulfur cluster binding
PSTA_RS15835	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PSTA_RS15855	COG2815	serine threonine protein kinase
PSTA_RS15855	COG0515	serine threonine protein kinase
PSTA_RS15880	COG0714	Associated with various cellular activities
PSTA_RS15930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS15945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PSTA_RS15955	COG5002	protein histidine kinase activity
PSTA_RS15970	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PSTA_RS15975	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PSTA_RS16000	COG0693	protein deglycase activity
PSTA_RS16005	COG3132	Protein of unknown function, DUF480
PSTA_RS16010	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PSTA_RS16015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS16040	COG0525	valine-tRNA ligase activity
PSTA_RS16045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PSTA_RS16050	COG1363	Peptidase, m42
PSTA_RS16090	COG2373	Large extracellular alpha-helical protein
PSTA_RS16100	COG1132	(ABC) transporter
PSTA_RS16105	COG1442	glycosyl transferase family 8
PSTA_RS16110	COG1442	glycosyl transferase family 8
PSTA_RS16115	COG1216	Glycosyl transferase, family 2
PSTA_RS16130	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PSTA_RS16135	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PSTA_RS16145	COG4869	propanediol catabolic process
PSTA_RS16155	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
PSTA_RS16165	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
PSTA_RS16190	COG0235	Class ii aldolase
PSTA_RS16195	COG0039	L-malate dehydrogenase activity
PSTA_RS16210	COG0129	dihydroxy-acid dehydratase activity
PSTA_RS16215	COG1174	glycine betaine transport
PSTA_RS16220	COG1125	glycine betaine transport
PSTA_RS16220	COG0517	IMP dehydrogenase activity
PSTA_RS16230	COG4537	Required for transformation and DNA binding
PSTA_RS16265	COG5002	protein histidine kinase activity
PSTA_RS16300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PSTA_RS16305	COG2201	protein-glutamate methylesterase activity
PSTA_RS16310	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PSTA_RS16335	COG0835	chemotaxis
PSTA_RS16345	COG0745	RESPONSE REGULATOR receiver
PSTA_RS16370	COG0714	Associated with various cellular activities
PSTA_RS16390	COG1132	(ABC) transporter
PSTA_RS16460	COG0643	Histidine kinase
PSTA_RS16460	COG2198	Histidine kinase
PSTA_RS16460	COG0784	Response regulator, receiver
PSTA_RS16465	COG0835	chemotaxis
PSTA_RS16475	COG0745	RESPONSE REGULATOR receiver
PSTA_RS16480	COG2201	protein-glutamate methylesterase activity
PSTA_RS16525	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PSTA_RS16530	COG0434	BtpA family
PSTA_RS16535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PSTA_RS16540	COG2076	Multidrug Resistance protein
PSTA_RS16585	COG0589	response to stress
PSTA_RS16620	COG0673	inositol 2-dehydrogenase activity
PSTA_RS16660	COG1181	Belongs to the D-alanine--D-alanine ligase family
PSTA_RS16680	COG0247	lactate metabolic process
PSTA_RS16685	COG1139	Iron-sulfur cluster binding protein
PSTA_RS16690	COG1556	Lactate utilization protein
PSTA_RS16700	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PSTA_RS16715	COG2815	serine threonine protein kinase
PSTA_RS16715	COG0515	serine threonine protein kinase
PSTA_RS16760	COG0745	RESPONSE REGULATOR receiver
PSTA_RS16765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS16840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PSTA_RS16855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS16865	COG1111	helicase
PSTA_RS16865	COG1205	dead DEAH box helicase
PSTA_RS16870	COG0210	DNA helicase
PSTA_RS16910	COG4372	Transposase
PSTA_RS17025	COG2226	methyltransferase
PSTA_RS17040	COG1940	carbohydrate kinase activity
PSTA_RS17045	COG0667	Aldo Keto reductase
PSTA_RS17075	COG1366	Belongs to the anti-sigma-factor antagonist family
PSTA_RS17085	COG0673	inositol 2-dehydrogenase activity
PSTA_RS17275	COG2217	Heavy metal translocating P-type atpase
PSTA_RS17325	COG0640	Transcriptional regulator
PSTA_RS17330	COG0673	inositol 2-dehydrogenase activity
PSTA_RS17345	COG0384	phenazine biosynthesis protein PhzF
PSTA_RS17360	COG4112	unkown
PSTA_RS17365	COG3622	Belongs to the hyi family
PSTA_RS17370	COG2217	Heavy metal translocating P-type atpase
PSTA_RS17375	COG1546	Belongs to the CinA family
PSTA_RS17375	COG1058	Belongs to the CinA family
PSTA_RS17380	COG2319	Wd-40 repeat
PSTA_RS17380	COG5635	Nacht domain
PSTA_RS17400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PSTA_RS17400	COG1754	DNA topoisomerase type I activity
PSTA_RS17405	COG0736	holo-[acyl-carrier-protein] synthase activity
PSTA_RS17410	COG5002	protein histidine kinase activity
PSTA_RS17445	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PSTA_RS17465	COG0588	phosphoglycerate mutase activity
PSTA_RS17470	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PSTA_RS17475	COG0248	Ppx GppA phosphatase
PSTA_RS17500	COG1191	sigma factor activity
PSTA_RS17520	COG1419	protein localization to endoplasmic reticulum
PSTA_RS17525	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PSTA_RS17540	COG0750	zinc metalloprotease
PSTA_RS17545	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PSTA_RS17550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PSTA_RS17580	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PSTA_RS17590	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS17620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PSTA_RS17625	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS17655	COG0632	four-way junction helicase activity
PSTA_RS17660	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PSTA_RS17665	COG0215	cysteine-tRNA ligase activity
PSTA_RS17670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PSTA_RS17715	COG0673	inositol 2-dehydrogenase activity
PSTA_RS17725	COG4537	Required for transformation and DNA binding
PSTA_RS17750	COG0204	Acyl-transferase
PSTA_RS17755	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PSTA_RS17755	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PSTA_RS17790	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PSTA_RS17835	COG4717	serine-type aminopeptidase activity
PSTA_RS17895	COG1450	Type ii and iii secretion system protein
PSTA_RS17900	COG5002	protein histidine kinase activity
PSTA_RS17905	COG0745	RESPONSE REGULATOR receiver
PSTA_RS17915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PSTA_RS17920	COG1459	type II secretion system
PSTA_RS17925	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PSTA_RS17930	COG1242	4 iron, 4 sulfur cluster binding
PSTA_RS17960	COG3119	arylsulfatase activity
PSTA_RS17990	COG3852	Histidine kinase
PSTA_RS18005	COG0626	cystathionine gamma-synthase activity
PSTA_RS18010	COG0626	cystathionine gamma-synthase activity
PSTA_RS18030	COG0571	ribonuclease III activity
PSTA_RS18035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PSTA_RS18095	COG1459	type II secretion system
PSTA_RS18100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PSTA_RS18130	COG3119	arylsulfatase activity
PSTA_RS18135	COG1418	mRNA catabolic process
PSTA_RS18150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PSTA_RS18160	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PSTA_RS18165	COG0717	Belongs to the dCTP deaminase family
PSTA_RS18170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PSTA_RS18205	COG4372	Transposase
PSTA_RS18325	COG3119	arylsulfatase activity
PSTA_RS18335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PSTA_RS18355	COG3779	Protein conserved in bacteria
PSTA_RS18360	COG0459	protein refolding
PSTA_RS18365	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PSTA_RS18405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PSTA_RS18425	COG0473	3-isopropylmalate dehydrogenase activity
PSTA_RS18430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PSTA_RS18490	COG1132	(ABC) transporter
PSTA_RS18495	COG1253	flavin adenine dinucleotide binding
PSTA_RS18520	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PSTA_RS18545	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PSTA_RS18550	COG2755	lipolytic protein G-D-S-L family
PSTA_RS18550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PSTA_RS18555	COG1070	Carbohydrate kinase
PSTA_RS18580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PSTA_RS18585	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PSTA_RS18590	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PSTA_RS18595	COG0793	Belongs to the peptidase S41A family
PSTA_RS18605	COG1131	(ABC) transporter
PSTA_RS18615	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PSTA_RS18630	COG0237	dephospho-CoA kinase activity
PSTA_RS18635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PSTA_RS18635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PSTA_RS18690	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PSTA_RS18695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS18700	COG2226	methyltransferase
PSTA_RS18705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PSTA_RS18710	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PSTA_RS18710	COG3608	succinylglutamate desuccinylase aspartoacylase
PSTA_RS18725	COG1131	(ABC) transporter
PSTA_RS18740	COG0598	Magnesium transport protein CorA
PSTA_RS18745	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PSTA_RS18745	COG3264	Mechanosensitive ion channel
PSTA_RS18760	COG0159	tryptophan synthase activity
PSTA_RS18765	COG0133	tryptophan synthase activity
PSTA_RS18775	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PSTA_RS18790	COG0405	Gamma-glutamyltransferase
PSTA_RS18825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PSTA_RS18875	COG3869	Catalyzes the specific phosphorylation of arginine residues in
PSTA_RS18890	COG4566	intracellular signal transduction
PSTA_RS18925	COG0726	polysaccharide deacetylase
PSTA_RS18935	COG0137	argininosuccinate synthase activity
PSTA_RS18940	COG1691	(AIR) carboxylase
PSTA_RS18945	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PSTA_RS18945	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PSTA_RS18955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PSTA_RS19060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PSTA_RS19065	COG1678	Uncharacterized ACR, COG1678
PSTA_RS19075	COG0745	RESPONSE REGULATOR receiver
PSTA_RS19085	COG1446	asparaginase
PSTA_RS19110	COG0724	RNA recognition motif
PSTA_RS19165	COG1082	Xylose isomerase domain protein TIM barrel
PSTA_RS19180	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PSTA_RS19185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PSTA_RS19245	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PSTA_RS19255	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PSTA_RS19270	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS19280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS19285	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PSTA_RS19290	COG0802	atpase or kinase
PSTA_RS19300	COG4284	Utp--glucose-1-phosphate uridylyltransferase
PSTA_RS19305	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PSTA_RS19305	COG0662	Cupin 2, conserved barrel domain protein
PSTA_RS19315	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PSTA_RS19325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS19325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS19330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS19335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSTA_RS19350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PSTA_RS19365	COG0450	alkyl hydroperoxide reductase
PSTA_RS19370	COG1078	dGTPase activity
PSTA_RS19380	COG0823	Involved in the tonB-independent uptake of proteins
PSTA_RS19380	COG1506	peptidase
PSTA_RS19380	COG4946	Tricorn protease homolog
PSTA_RS19385	COG0154	amidase activity
PSTA_RS19400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PSTA_RS19410	COG1858	cytochrome C peroxidase
PSTA_RS19415	COG0066	3-isopropylmalate dehydratase activity
PSTA_RS19420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PSTA_RS19425	COG0515	serine threonine protein kinase
PSTA_RS19425	COG2815	serine threonine protein kinase
PSTA_RS19430	COG2197	response regulator
PSTA_RS19450	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PSTA_RS19455	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PSTA_RS19480	COG3119	arylsulfatase activity
PSTA_RS19485	COG3119	arylsulfatase activity
PSTA_RS19490	COG3119	arylsulfatase activity
PSTA_RS19505	COG3119	arylsulfatase activity
PSTA_RS19510	COG3119	arylsulfatase activity
PSTA_RS19535	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PSTA_RS19540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PSTA_RS19550	COG1722	exodeoxyribonuclease VII activity
PSTA_RS19555	COG1570	exodeoxyribonuclease VII activity
PSTA_RS19560	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PSTA_RS19585	COG0037	tRNA processing
PSTA_RS19590	COG1418	mRNA catabolic process
PSTA_RS19595	COG1692	metallophosphoesterase
PSTA_RS19630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PSTA_RS19635	COG1862	Preprotein translocase
PSTA_RS19640	COG0343	queuine tRNA-ribosyltransferase activity
PSTA_RS19645	COG0202	RNA polymerase activity
PSTA_RS19660	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PSTA_RS19675	COG0714	Associated with various cellular activities
PSTA_RS19700	COG0400	carboxylic ester hydrolase activity
PSTA_RS19725	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PSTA_RS19730	COG1185	polyribonucleotide nucleotidyltransferase activity
PSTA_RS19735	COG5002	protein histidine kinase activity
PSTA_RS19765	COG2217	Heavy metal translocating P-type atpase
PSTA_RS19780	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PSTA_RS19785	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PSTA_RS19790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PSTA_RS19795	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PSTA_RS19800	COG2204	response regulator
PSTA_RS19825	COG0288	reversible hydration of carbon dioxide
PSTA_RS19830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PSTA_RS19860	COG0165	Argininosuccinate lyase
PSTA_RS19875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PSTA_RS19905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PSTA_RS19925	COG2815	serine threonine protein kinase
PSTA_RS19925	COG0515	serine threonine protein kinase
PSTA_RS19930	COG1595	DNA-templated transcription, initiation
PSTA_RS19935	COG1595	DNA-templated transcription, initiation
PSTA_RS19960	COG0673	inositol 2-dehydrogenase activity
PSTA_RS19970	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PSTA_RS19975	COG0488	(ABC) transporter
PSTA_RS20010	COG2201	protein-glutamate methylesterase activity
PSTA_RS20015	COG0493	'glutamate synthase
PSTA_RS20020	COG0535	radical SAM domain protein
PSTA_RS20060	COG1595	DNA-templated transcription, initiation
PSTA_RS20065	COG1595	DNA-templated transcription, initiation
PSTA_RS20075	COG0604	alcohol dehydrogenase
PSTA_RS20080	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PSTA_RS20095	COG0668	transmembrane transport
PSTA_RS20120	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PSTA_RS20125	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSTA_RS20130	COG0243	molybdopterin cofactor binding
PSTA_RS20135	COG0437	4 iron, 4 sulfur cluster binding
PSTA_RS20140	COG1116	anion transmembrane transporter activity
PSTA_RS20145	COG1116	anion transmembrane transporter activity
PSTA_RS20150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSTA_RS20155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PSTA_RS20175	COG0784	Response regulator, receiver
PSTA_RS20175	COG2205	protein histidine kinase activity
PSTA_RS20180	COG0745	RESPONSE REGULATOR receiver
PSTA_RS20185	COG2205	protein histidine kinase activity
PSTA_RS20190	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PSTA_RS20195	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PSTA_RS20200	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PSTA_RS20215	COG3119	arylsulfatase activity
PSTA_RS20245	COG0590	tRNA wobble adenosine to inosine editing
PSTA_RS20250	COG1305	Transglutaminase-like
PSTA_RS20260	COG0714	Associated with various cellular activities
PSTA_RS20290	COG0673	inositol 2-dehydrogenase activity
PSTA_RS20315	COG3119	arylsulfatase activity
PSTA_RS20315	COG3408	Glycogen debranching enzyme
PSTA_RS20320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PSTA_RS20325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PSTA_RS20345	COG0009	L-threonylcarbamoyladenylate synthase
PSTA_RS20360	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PSTA_RS20365	COG0347	Belongs to the P(II) protein family
PSTA_RS20370	COG0004	ammonium transporteR
PSTA_RS20375	COG2096	Adenosyltransferase
PSTA_RS20455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PSTA_RS20495	COG0793	Belongs to the peptidase S41A family
PSTA_RS20500	COG0321	lipoyl(octanoyl) transferase activity
PSTA_RS20500	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PSTA_RS20505	COG0653	protein targeting
PSTA_RS20510	COG1519	Transferase
PSTA_RS20520	COG0800	Aldolase
PSTA_RS20530	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PSTA_RS20625	COG4974	Belongs to the 'phage' integrase family
PSTA_RS20630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PSTA_RS20645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PSTA_RS20675	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PSTA_RS20685	COG3119	arylsulfatase activity
PSTA_RS20700	COG4864	UPF0365 protein
PSTA_RS20705	COG0482	sulfurtransferase activity
PSTA_RS20735	COG0594	ribonuclease P activity
PSTA_RS20740	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PSTA_RS20745	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PSTA_RS20750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PSTA_RS20755	COG0154	amidase activity
PSTA_RS20760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PSTA_RS20770	COG0101	tRNA pseudouridine synthase activity
PSTA_RS20780	COG0515	serine threonine protein kinase
PSTA_RS20780	COG2815	serine threonine protein kinase
PSTA_RS20785	COG0825	malonyl-CoA metabolic process
PSTA_RS20790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PSTA_RS20810	COG1490	D-aminoacyl-tRNA deacylase activity
PSTA_RS20845	COG1073	alpha beta
PSTA_RS20850	COG0436	Aminotransferase
PSTA_RS20860	COG1082	Xylose isomerase domain protein TIM barrel
PSTA_RS20890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PSTA_RS20895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PSTA_RS20910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSTA_RS20915	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PSTA_RS20920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PSTA_RS20925	COG0556	nucleotide-excision repair
PSTA_RS20970	COG3119	arylsulfatase activity
PSTA_RS20975	COG0521	Mo-molybdopterin cofactor biosynthetic process
PSTA_RS20990	COG2115	Belongs to the xylose isomerase family
PSTA_RS21000	COG0596	Alpha beta hydrolase
PSTA_RS21025	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PSTA_RS21030	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PSTA_RS21035	COG2203	Gaf domain
PSTA_RS21035	COG5001	Diguanylate cyclase
PSTA_RS21035	COG4251	negative regulation of phosphorylation
PSTA_RS21035	COG3706	GGDEF domain
PSTA_RS21055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSTA_RS21065	COG0516	GMP reductase activity
PSTA_RS21065	COG0517	IMP dehydrogenase activity
PSTA_RS21075	COG4948	Mandelate Racemase Muconate Lactonizing
PSTA_RS21125	COG4191	Histidine kinase
PSTA_RS21130	COG0784	Response regulator, receiver
PSTA_RS21155	COG1214	PFAM Peptidase M22, glycoprotease
PSTA_RS21180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS21180	COG0706	membrane insertase activity
PSTA_RS21185	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PSTA_RS21195	COG0527	aspartate kinase activity
PSTA_RS21200	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
PSTA_RS21210	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PSTA_RS21215	COG3494	Protein of unknown function (DUF1009)
PSTA_RS21245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PSTA_RS21270	COG0463	Glycosyl transferase, family 2
PSTA_RS21280	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PSTA_RS21285	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS21300	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PSTA_RS21305	COG0045	succinate-CoA ligase (ADP-forming) activity
PSTA_RS21310	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS21325	COG0039	L-malate dehydrogenase activity
PSTA_RS21345	COG3852	Histidine kinase
PSTA_RS21350	COG2204	response regulator
PSTA_RS21365	COG1677	Flagellar hook-basal body complex protein FliE
PSTA_RS21375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PSTA_RS21385	COG1157	protein secretion by the type III secretion system
PSTA_RS21405	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PSTA_RS21410	COG1749	Flagellar hook protein flgE
PSTA_RS21415	COG1582	Flagellar protein (FlbD)
PSTA_RS21445	COG1338	Plays a role in the flagellum-specific transport system
PSTA_RS21450	COG1987	bacterial-type flagellum assembly
PSTA_RS21460	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PSTA_RS21475	COG0596	Alpha beta hydrolase
PSTA_RS21480	COG1028	Short-chain dehydrogenase reductase Sdr
PSTA_RS21485	COG2045	Belongs to the ComB family
PSTA_RS21490	COG0423	glycine-tRNA ligase activity
PSTA_RS21545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PSTA_RS21585	COG1063	alcohol dehydrogenase
PSTA_RS21590	COG1396	sequence-specific DNA binding
PSTA_RS21595	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PSTA_RS21600	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PSTA_RS21605	COG0131	Imidazoleglycerol-phosphate dehydratase
PSTA_RS21620	COG3119	arylsulfatase activity
PSTA_RS21680	COG1606	tRNA processing
PSTA_RS21705	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PSTA_RS21720	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PSTA_RS21730	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PSTA_RS21735	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PSTA_RS21740	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PSTA_RS21770	COG1045	serine acetyltransferase
PSTA_RS21775	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PSTA_RS21780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PSTA_RS21800	COG1073	alpha beta
PSTA_RS21810	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PSTA_RS21875	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PSTA_RS21880	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
PSTA_RS21915	COG2378	regulation of single-species biofilm formation
PSTA_RS21935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PSTA_RS21955	COG1864	DNA RNA non-specific endonuclease
PSTA_RS21955	COG3591	Belongs to the peptidase S1B family
PSTA_RS21970	COG2356	endonuclease I
PSTA_RS21980	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PSTA_RS22040	COG0006	proline dipeptidase activity
PSTA_RS22045	COG0511	ligase activity, forming carbon-carbon bonds
PSTA_RS22050	COG0439	Biotin carboxylase
PSTA_RS22055	COG0673	inositol 2-dehydrogenase activity
PSTA_RS22060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PSTA_RS22065	COG0540	Belongs to the ATCase OTCase family
PSTA_RS22085	COG0004	ammonium transporteR
PSTA_RS22095	COG0552	protein localization to endoplasmic reticulum
PSTA_RS22100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PSTA_RS22105	COG3064	Membrane
PSTA_RS22105	COG4991	sh3 domain protein
PSTA_RS22105	COG0515	serine threonine protein kinase
PSTA_RS22110	COG2255	four-way junction helicase activity
PSTA_RS22140	COG1454	alcohol dehydrogenase
PSTA_RS22200	COG0463	Glycosyl transferase, family 2
PSTA_RS22225	COG0725	ABC transporter, periplasmic molybdate-binding protein
PSTA_RS22230	COG4149	molybdate abc transporter
PSTA_RS22235	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PSTA_RS22240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PSTA_RS22285	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PSTA_RS22290	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PSTA_RS22330	COG1131	(ABC) transporter
PSTA_RS22350	COG0719	Fe-S assembly protein
PSTA_RS22355	COG0719	Fe-S assembly protein
PSTA_RS22360	COG0396	ATPase activity
PSTA_RS22365	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSTA_RS22400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PSTA_RS22405	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PSTA_RS22415	COG0210	DNA helicase
PSTA_RS22445	COG2197	response regulator
PSTA_RS22515	COG1215	transferase activity, transferring glycosyl groups
PSTA_RS22530	COG2165	general secretion pathway protein
PSTA_RS22535	COG0673	inositol 2-dehydrogenase activity
PSTA_RS22570	COG4941	Belongs to the sigma-70 factor family
PSTA_RS22575	COG2020	methyltransferase activity
PSTA_RS22585	COG1294	oxidase, subunit
PSTA_RS22590	COG1271	oxidase subunit
PSTA_RS22640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PSTA_RS22650	COG3119	arylsulfatase activity
PSTA_RS22665	COG0436	Aminotransferase
PSTA_RS22675	COG0505	Belongs to the CarA family
PSTA_RS22710	COG1139	Iron-sulfur cluster binding protein
PSTA_RS22720	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PSTA_RS22745	COG0488	(ABC) transporter
PSTA_RS22750	COG1054	Belongs to the UPF0176 family
PSTA_RS22805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PSTA_RS22810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PSTA_RS22840	COG4335	DNA alkylation repair
PSTA_RS22845	COG0045	succinate-CoA ligase (ADP-forming) activity
PSTA_RS22845	COG1042	CoA-binding domain protein
PSTA_RS22845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PSTA_RS22860	COG3320	Male sterility
PSTA_RS22860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PSTA_RS22885	COG0268	Binds directly to 16S ribosomal RNA
PSTA_RS22890	COG0543	2 iron, 2 sulfur cluster binding
PSTA_RS22910	COG1482	cell wall glycoprotein biosynthetic process
PSTA_RS22920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PSTA_RS22935	COG2251	uridine kinase activity
PSTA_RS22935	COG0195	Participates in both transcription termination and antitermination
PSTA_RS22940	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PSTA_RS22945	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PSTA_RS22970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PSTA_RS22980	COG0442	prolyl-tRNA aminoacylation
PSTA_RS23000	COG0095	Lipoate-protein ligase
PSTA_RS23005	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PSTA_RS23010	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PSTA_RS23015	COG0509	glycine decarboxylation via glycine cleavage system
PSTA_RS23020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PSTA_RS23025	COG0803	Belongs to the bacterial solute-binding protein 9 family
PSTA_RS23030	COG1121	(ABC) transporter
PSTA_RS23040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PSTA_RS23065	COG0557	exoribonuclease II activity
PSTA_RS23090	COG3481	metal-dependent phosphohydrolase, HD sub domain
PSTA_RS23095	COG0440	acetolactate synthase activity
PSTA_RS23100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PSTA_RS23135	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PSTA_RS23150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSTA_RS23155	COG0402	S-adenosylhomocysteine deaminase activity
PSTA_RS23160	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PSTA_RS23165	COG0140	phosphoribosyl-ATP diphosphatase activity
PSTA_RS23180	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PSTA_RS23185	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PSTA_RS23205	COG2195	Cleaves the N-terminal amino acid of tripeptides
PSTA_RS23210	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PSTA_RS23225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PSTA_RS23235	COG0481	GTPase activity
PSTA_RS23240	COG1940	carbohydrate kinase activity
PSTA_RS23245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PSTA_RS23270	COG4974	Belongs to the 'phage' integrase family
PSTA_RS23295	COG1136	(ABC) transporter
PSTA_RS23300	COG0577	efflux transmembrane transporter activity
PSTA_RS23320	COG1595	DNA-templated transcription, initiation
PSTA_RS23345	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PSTA_RS23350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PSTA_RS23360	COG2204	response regulator
PSTA_RS23365	COG2197	response regulator
PSTA_RS23390	COG0673	inositol 2-dehydrogenase activity
PSTA_RS23395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PSTA_RS23400	COG1164	Oligoendopeptidase f
PSTA_RS23415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PSTA_RS23430	COG3481	metal-dependent phosphohydrolase, HD sub domain
PSTA_RS23440	COG2890	protein-(glutamine-N5) methyltransferase activity
PSTA_RS23445	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PSTA_RS23450	COG0254	rRNA binding
PSTA_RS23460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PSTA_RS23485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS23515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS23530	COG2183	response to ionizing radiation
PSTA_RS23535	COG2815	serine threonine protein kinase
PSTA_RS23535	COG0515	serine threonine protein kinase
PSTA_RS23575	COG4191	Histidine kinase
PSTA_RS23600	COG0515	serine threonine protein kinase
PSTA_RS23600	COG2815	serine threonine protein kinase
PSTA_RS23640	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PSTA_RS23685	COG1361	Conserved repeat domain
PSTA_RS23735	COG1408	metallophosphoesterase
PSTA_RS23745	COG0839	Belongs to the complex I subunit 6 family
PSTA_RS23760	COG0004	ammonium transporteR
PSTA_RS23785	COG2199	diguanylate cyclase activity
PSTA_RS23820	COG0742	ribosomal rna small subunit methyltransferase
PSTA_RS23865	COG3604	Transcriptional regulator
PSTA_RS23930	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PSTA_RS23945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSTA_RS23980	COG0318	PFAM AMP-dependent synthetase and ligase
PSTA_RS23980	COG0204	Acyl-transferase
PSTA_RS23985	COG4964	Belongs to the GSP D family
PSTA_RS23990	COG2205	protein histidine kinase activity
PSTA_RS23990	COG3850	Histidine kinase
PSTA_RS23990	COG3437	response regulator, receiver
PSTA_RS23990	COG4999	Histidine kinase
PSTA_RS24000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PSTA_RS24020	COG0861	Integral membrane protein TerC family
PSTA_RS24025	COG0631	protein serine/threonine phosphatase activity
PSTA_RS24050	COG1595	DNA-templated transcription, initiation
PSTA_RS24110	COG0848	biopolymer transport protein
PSTA_RS24120	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PSTA_RS24125	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PSTA_RS24230	COG0154	amidase activity
PSTA_RS24235	COG4589	Belongs to the CDS family
PSTA_RS24240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS24270	COG0515	serine threonine protein kinase
PSTA_RS24290	COG0277	FAD linked oxidase domain protein
PSTA_RS24300	COG0848	biopolymer transport protein
PSTA_RS24305	COG0848	biopolymer transport protein
PSTA_RS24310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS24345	COG0328	RNA-DNA hybrid ribonuclease activity
PSTA_RS24360	COG2815	serine threonine protein kinase
PSTA_RS24360	COG0515	serine threonine protein kinase
PSTA_RS24420	COG1921	L-seryl-tRNASec selenium transferase activity
PSTA_RS24425	COG0673	inositol 2-dehydrogenase activity
PSTA_RS24460	COG0839	Belongs to the complex I subunit 6 family
PSTA_RS24470	COG1007	ATP synthesis coupled electron transport
PSTA_RS24490	COG1404	Belongs to the peptidase S8 family
PSTA_RS24515	COG2198	Histidine kinase
PSTA_RS24515	COG0643	Histidine kinase
PSTA_RS24530	COG0515	serine threonine protein kinase
PSTA_RS24530	COG2815	serine threonine protein kinase
PSTA_RS24540	COG0784	Response regulator, receiver
PSTA_RS24560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSTA_RS24565	COG1401	restriction endodeoxyribonuclease activity
PSTA_RS24600	COG0515	serine threonine protein kinase
PSTA_RS24600	COG2815	serine threonine protein kinase
PSTA_RS24630	COG4964	Belongs to the GSP D family
PSTA_RS24655	COG0628	permease
PSTA_RS24670	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PSTA_RS24760	COG0515	serine threonine protein kinase
PSTA_RS24770	COG2226	methyltransferase
PSTA_RS24795	COG1959	2 iron, 2 sulfur cluster binding
PSTA_RS24840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PSTA_RS24840	COG1333	cytochrome c biogenesis protein
PSTA_RS24845	COG3386	PFAM SMP-30 Gluconolaconase
PSTA_RS24870	COG1595	DNA-templated transcription, initiation
PSTA_RS24880	COG0004	ammonium transporteR
PSTA_RS24885	COG2176	DNA-directed DNA polymerase activity
PSTA_RS24900	COG4251	negative regulation of phosphorylation
PSTA_RS24925	COG0515	serine threonine protein kinase
PSTA_RS24925	COG2815	serine threonine protein kinase
PSTA_RS24930	COG0356	it plays a direct role in the translocation of protons across the membrane
PSTA_RS24935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PSTA_RS24940	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PSTA_RS24960	COG0784	Response regulator, receiver
PSTA_RS24960	COG2205	protein histidine kinase activity
PSTA_RS24960	COG5002	protein histidine kinase activity
PSTA_RS24975	COG4191	Histidine kinase
PSTA_RS24990	COG0515	serine threonine protein kinase
PSTA_RS24990	COG2815	serine threonine protein kinase
PSTA_RS25000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PSTA_RS25005	COG1556	Lactate utilization protein
PSTA_RS25010	COG0657	acetylesterase activity
PSTA_RS25015	COG1187	pseudouridine synthase activity
PSTA_RS25025	COG0805	protein transport
PSTA_RS25030	COG3842	ATPase activity
PSTA_RS25045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PSTA_RS25045	COG1321	iron dependent repressor