locus-tag	class	description
KU39_RS00005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KU39_RS00010	COG0594	ribonuclease P activity
KU39_RS00015	COG0706	membrane insertase activity
KU39_RS00020	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KU39_RS00035	COG1192	Involved in chromosome partitioning
KU39_RS00040	COG1475	DNA binding
KU39_RS00050	COG0356	it plays a direct role in the translocation of protons across the membrane
KU39_RS00060	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KU39_RS00065	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KU39_RS00070	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KU39_RS00075	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KU39_RS00080	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KU39_RS00090	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KU39_RS00095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KU39_RS00120	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS00140	COG0489	protein tyrosine kinase activity
KU39_RS00170	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS00185	COG0517	IMP dehydrogenase activity
KU39_RS00185	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KU39_RS00195	COG2867	negative regulation of translational initiation
KU39_RS00195	COG2226	methyltransferase
KU39_RS00210	COG2814	Major facilitator Superfamily
KU39_RS00230	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KU39_RS00235	COG0109	protoheme IX farnesyltransferase activity
KU39_RS00240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU39_RS00330	COG4221	oxidoreductase activity
KU39_RS00345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU39_RS00355	COG0189	ligase activity
KU39_RS00360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KU39_RS00365	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KU39_RS00385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KU39_RS00405	COG1678	Uncharacterized ACR, COG1678
KU39_RS00410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KU39_RS00435	COG0814	amino acid
KU39_RS00440	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KU39_RS00445	COG0281	malic enzyme
KU39_RS00455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU39_RS00465	COG4221	oxidoreductase activity
KU39_RS00500	COG0489	protein tyrosine kinase activity
KU39_RS00500	COG3206	protein involved in exopolysaccharide biosynthesis
KU39_RS00505	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KU39_RS00520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KU39_RS00530	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KU39_RS00535	COG1215	transferase activity, transferring glycosyl groups
KU39_RS00545	COG0297	glycogen (starch) synthase activity
KU39_RS00550	COG0438	transferase activity, transferring glycosyl groups
KU39_RS00565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KU39_RS00575	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KU39_RS00575	COG2885	chlorophyll binding
KU39_RS00580	COG1278	Cold shock
KU39_RS00585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KU39_RS00590	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS00595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU39_RS00600	COG0745	RESPONSE REGULATOR receiver
KU39_RS00620	COG0181	hydroxymethylbilane synthase activity
KU39_RS00675	COG0583	DNA-binding transcription factor activity
KU39_RS00690	COG0210	DNA helicase
KU39_RS00700	COG0531	amino acid
KU39_RS00710	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KU39_RS00720	COG0318	PFAM AMP-dependent synthetase and ligase
KU39_RS00740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU39_RS00745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU39_RS00805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU39_RS00810	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KU39_RS00815	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KU39_RS00825	COG1054	Belongs to the UPF0176 family
KU39_RS00840	COG2027	D-alanyl-D-alanine carboxypeptidase
KU39_RS00845	COG2027	D-alanyl-D-alanine carboxypeptidase
KU39_RS00860	COG0210	DNA helicase
KU39_RS00875	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KU39_RS00880	COG0788	formyltetrahydrofolate deformylase activity
KU39_RS00910	COG0259	pyridoxamine-phosphate oxidase activity
KU39_RS00940	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KU39_RS00960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KU39_RS00965	COG2119	membrane
KU39_RS01010	COG1534	Rna-binding protein
KU39_RS01020	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KU39_RS01025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU39_RS01030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU39_RS01040	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU39_RS01045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU39_RS01070	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KU39_RS01075	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KU39_RS01080	COG0511	ligase activity, forming carbon-carbon bonds
KU39_RS01085	COG0439	Biotin carboxylase
KU39_RS01100	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KU39_RS01105	COG0138	bifunctional purine biosynthesis protein purh
KU39_RS01110	COG0151	Belongs to the GarS family
KU39_RS01115	COG0006	proline dipeptidase activity
KU39_RS01130	COG0745	RESPONSE REGULATOR receiver
KU39_RS01135	COG0531	amino acid
KU39_RS01155	COG2925	Exonuclease
KU39_RS01165	COG2011	ABC-type metal ion transport system permease component
KU39_RS01185	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KU39_RS01190	COG2070	2-Nitropropane dioxygenase
KU39_RS01195	COG0586	Pfam SNARE associated Golgi protein
KU39_RS01200	COG4536	flavin adenine dinucleotide binding
KU39_RS01205	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KU39_RS01210	COG2995	paraquat-inducible protein a
KU39_RS01235	COG1301	dicarboxylic acid transport
KU39_RS01245	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KU39_RS01270	COG3104	oligopeptide transport
KU39_RS01275	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KU39_RS01285	COG2801	Transposase and inactivated derivatives
KU39_RS01300	COG0552	protein localization to endoplasmic reticulum
KU39_RS01335	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS01395	COG1183	phosphatidylcholine synthase activity
KU39_RS01405	COG0456	acetyltransferase
KU39_RS01415	COG0084	hydrolase, TatD family'
KU39_RS01425	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KU39_RS01480	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KU39_RS01515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KU39_RS01525	COG1773	rubredoxin
KU39_RS01530	COG1981	membrane
KU39_RS01535	COG0316	Belongs to the HesB IscA family
KU39_RS01575	COG0084	hydrolase, TatD family'
KU39_RS01590	COG1028	Short-chain dehydrogenase reductase Sdr
KU39_RS01605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU39_RS01610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU39_RS01625	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS01640	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KU39_RS01650	COG0833	amino acid
KU39_RS01675	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS01705	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KU39_RS01710	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS01730	COG3385	transposase activity
KU39_RS01740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KU39_RS01795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KU39_RS01825	COG2205	protein histidine kinase activity
KU39_RS01835	COG0500	methyltransferase
KU39_RS01860	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS01870	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS01875	COG0308	aminopeptidase N
KU39_RS01885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU39_RS01890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU39_RS01915	COG1113	amino acid transport
KU39_RS01940	COG0837	glucose binding
KU39_RS01950	COG3852	Histidine kinase
KU39_RS01960	COG1677	Flagellar hook-basal body complex protein FliE
KU39_RS01970	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KU39_RS02015	COG2009	succinate dehydrogenase
KU39_RS02020	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KU39_RS02025	COG1053	succinate dehydrogenase
KU39_RS02030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KU39_RS02045	COG0045	succinate-CoA ligase (ADP-forming) activity
KU39_RS02065	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS02090	COG1918	ferrous iron import across plasma membrane
KU39_RS02095	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KU39_RS02105	COG0625	glutathione transferase activity
KU39_RS02110	COG2969	positive regulation of protein catabolic process
KU39_RS02115	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KU39_RS02120	COG0792	nuclease activity
KU39_RS02130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KU39_RS02135	COG0142	geranyltranstransferase activity
KU39_RS02140	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KU39_RS02150	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KU39_RS02155	COG0840	transmembrane signaling receptor activity
KU39_RS02165	COG1509	lysine 2,3-aminomutase activity
KU39_RS02170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KU39_RS02175	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KU39_RS02200	COG0438	transferase activity, transferring glycosyl groups
KU39_RS02205	COG0436	Aminotransferase
KU39_RS02210	COG0556	nucleotide-excision repair
KU39_RS02225	COG1086	Polysaccharide biosynthesis protein
KU39_RS02230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KU39_RS02235	COG1083	cytidylyl-transferase
KU39_RS02245	COG2089	acid synthase
KU39_RS02265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KU39_RS02270	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KU39_RS02275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KU39_RS02290	COG0072	phenylalanine-tRNA ligase activity
KU39_RS02295	COG0776	regulation of translation
KU39_RS02305	COG1881	PFAM PEBP family protein
KU39_RS02330	COG0069	glutamate synthase activity
KU39_RS02365	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS02380	COG2818	Glycosylase
KU39_RS02390	COG2963	transposase activity
KU39_RS02440	COG0728	peptidoglycan biosynthetic process
KU39_RS02445	COG0196	riboflavin kinase activity
KU39_RS02450	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS02455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KU39_RS02460	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KU39_RS02465	COG1047	Peptidyl-prolyl cis-trans
KU39_RS02470	COG2271	Major facilitator Superfamily
KU39_RS02480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KU39_RS02485	COG0840	transmembrane signaling receptor activity
KU39_RS02495	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS02530	COG1051	belongs to the nudix hydrolase family
KU39_RS02570	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS02600	COG0735	belongs to the Fur family
KU39_RS02605	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KU39_RS02620	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KU39_RS02625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KU39_RS02630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KU39_RS02665	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS02695	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KU39_RS02705	COG3385	transposase activity
KU39_RS02740	COG0835	chemotaxis
KU39_RS02740	COG0784	Response regulator, receiver
KU39_RS02760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU39_RS02765	COG2814	Major facilitator Superfamily
KU39_RS02770	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KU39_RS02775	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KU39_RS02790	COG2963	transposase activity
KU39_RS02795	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS02830	COG0307	riboflavin synthase, alpha
KU39_RS02835	COG0189	ligase activity
KU39_RS02855	COG2801	Transposase and inactivated derivatives
KU39_RS02860	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS02870	COG2177	Part of the ABC transporter FtsEX involved in
KU39_RS02875	COG2884	Cell division ATP-binding protein ftsE
KU39_RS02890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KU39_RS02895	COG3385	transposase activity
KU39_RS02910	COG0205	6-phosphofructokinase activity
KU39_RS02920	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KU39_RS02940	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS02955	COG0546	phosphoglycolate phosphatase activity
KU39_RS02970	COG2350	Protein conserved in bacteria
KU39_RS02975	COG2917	probably involved in intracellular septation
KU39_RS02980	COG0009	L-threonylcarbamoyladenylate synthase
KU39_RS02990	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KU39_RS03015	COG0739	heme binding
KU39_RS03020	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KU39_RS03030	COG0670	Belongs to the BI1 family
KU39_RS03035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KU39_RS03050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KU39_RS03070	COG2963	transposase activity
KU39_RS03080	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS03095	COG2801	Transposase and inactivated derivatives
KU39_RS03105	COG2963	transposase activity
KU39_RS03125	COG3240	lipase activity
KU39_RS03130	COG3385	transposase activity
KU39_RS03145	COG0742	ribosomal rna small subunit methyltransferase
KU39_RS03150	COG1760	l-serine dehydratase
KU39_RS03180	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KU39_RS03185	COG0471	metal ion transport
KU39_RS03185	COG3273	potassium ion transport
KU39_RS03225	COG0166	Belongs to the GPI family
KU39_RS03235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KU39_RS03240	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KU39_RS03265	COG3385	transposase activity
KU39_RS03275	COG2801	Transposase and inactivated derivatives
KU39_RS03290	COG3385	transposase activity
KU39_RS03295	COG2814	Major facilitator Superfamily
KU39_RS03300	COG0156	8-amino-7-oxononanoate synthase activity
KU39_RS03310	COG0179	Fumarylacetoacetate (FAA) hydrolase
KU39_RS03315	COG0784	Response regulator, receiver
KU39_RS03315	COG0835	chemotaxis
KU39_RS03345	COG2801	Transposase and inactivated derivatives
KU39_RS03360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KU39_RS03370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU39_RS03375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KU39_RS03385	COG2183	response to ionizing radiation
KU39_RS03405	COG2801	Transposase and inactivated derivatives
KU39_RS03410	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KU39_RS03415	COG2871	sodium ion transport
KU39_RS03420	COG1438	arginine binding
KU39_RS03470	COG2801	Transposase and inactivated derivatives
KU39_RS03495	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS03500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU39_RS03505	COG0154	amidase activity
KU39_RS03510	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU39_RS03515	COG1077	Cell shape determining protein MreB Mrl
KU39_RS03520	COG1792	Involved in formation and maintenance of cell shape
KU39_RS03530	COG0424	maF-like protein
KU39_RS03535	COG1530	ribonuclease E activity
KU39_RS03545	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KU39_RS03555	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS03560	COG3385	transposase activity
KU39_RS03565	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS03575	COG2171	N-acyltransferase activity
KU39_RS03580	COG0252	asparaginase activity
KU39_RS03585	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KU39_RS03595	COG0052	Belongs to the universal ribosomal protein uS2 family
KU39_RS03600	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KU39_RS03605	COG0528	UMP kinase activity
KU39_RS03610	COG0233	cytoplasmic translational termination
KU39_RS03615	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KU39_RS03620	COG0575	Belongs to the CDS family
KU39_RS03645	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KU39_RS03660	COG3425	synthase
KU39_RS03680	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU39_RS03685	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KU39_RS03690	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU39_RS03695	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU39_RS03700	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KU39_RS03705	COG0587	DNA-directed DNA polymerase activity
KU39_RS03710	COG0825	malonyl-CoA metabolic process
KU39_RS03715	COG0037	tRNA processing
KU39_RS03720	COG0659	secondary active sulfate transmembrane transporter activity
KU39_RS03750	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS03780	COG2223	nitrite transmembrane transporter activity
KU39_RS03815	COG2801	Transposase and inactivated derivatives
KU39_RS03915	COG0351	phosphomethylpyrimidine kinase
KU39_RS03940	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KU39_RS03950	COG1566	PFAM secretion protein HlyD family protein
KU39_RS03955	COG2814	Major facilitator Superfamily
KU39_RS03960	COG1538	Outer membrane efflux protein
KU39_RS03965	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KU39_RS03975	COG2197	response regulator
KU39_RS03980	COG0322	excinuclease ABC activity
KU39_RS04010	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS04020	COG2963	transposase activity
KU39_RS04075	COG2801	Transposase and inactivated derivatives
KU39_RS04090	COG3385	transposase activity
KU39_RS04110	COG0656	L-ascorbic acid biosynthetic process
KU39_RS04120	COG0477	Major facilitator Superfamily
KU39_RS04125	COG0235	Class ii aldolase
KU39_RS04135	COG0626	cystathionine gamma-synthase activity
KU39_RS04145	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KU39_RS04160	COG0544	peptidyl-prolyl cis-trans isomerase activity
KU39_RS04165	COG0740	serine-type endopeptidase activity
KU39_RS04170	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KU39_RS04175	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KU39_RS04190	COG1560	Kdo2-lipid A biosynthetic process
KU39_RS04195	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KU39_RS04205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU39_RS04210	COG2274	protein secretion by the type I secretion system
KU39_RS04215	COG2274	protein secretion by the type I secretion system
KU39_RS04220	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KU39_RS04230	COG1686	Belongs to the peptidase S11 family
KU39_RS04255	COG2801	Transposase and inactivated derivatives
KU39_RS04300	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS04305	COG0187	DNA topoisomerase II activity
KU39_RS04375	COG0776	regulation of translation
KU39_RS04380	COG0494	nUDIX hydrolase
KU39_RS04385	COG3385	transposase activity
KU39_RS04395	COG0039	L-malate dehydrogenase activity
KU39_RS04400	COG1538	Outer membrane efflux protein
KU39_RS04405	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KU39_RS04410	COG3150	esterase
KU39_RS04415	COG4988	ABC transporter
KU39_RS04420	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KU39_RS04445	COG3104	oligopeptide transport
KU39_RS04450	COG3385	transposase activity
KU39_RS04455	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS04480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KU39_RS04495	COG1546	Belongs to the CinA family
KU39_RS04495	COG1058	Belongs to the CinA family
KU39_RS04520	COG3385	transposase activity
KU39_RS04535	COG4948	Mandelate Racemase Muconate Lactonizing
KU39_RS04545	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU39_RS04550	COG0450	alkyl hydroperoxide reductase
KU39_RS04560	COG0500	methyltransferase
KU39_RS04565	COG3385	transposase activity
KU39_RS04585	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS04600	COG3385	transposase activity
KU39_RS04615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU39_RS04630	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KU39_RS04635	COG0531	amino acid
KU39_RS04640	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS04645	COG0531	amino acid
KU39_RS04650	COG2801	Transposase and inactivated derivatives
KU39_RS04740	COG2801	Transposase and inactivated derivatives
KU39_RS04770	COG0358	DNA primase activity
KU39_RS04775	COG1610	YqeY-like protein
KU39_RS04780	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KU39_RS04785	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KU39_RS04790	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KU39_RS04805	COG3385	transposase activity
KU39_RS04815	COG3385	transposase activity
KU39_RS04820	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS04840	COG1621	beta-fructofuranosidase activity
KU39_RS04860	COG0259	pyridoxamine-phosphate oxidase activity
KU39_RS04865	COG0589	response to stress
KU39_RS04875	COG1228	amidohydrolase
KU39_RS04885	COG2986	histidine ammonia-lyase
KU39_RS04910	COG3385	transposase activity
KU39_RS04930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KU39_RS04935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU39_RS04945	COG3956	TIGRFAM MazG family protein
KU39_RS04950	COG3956	TIGRFAM MazG family protein
KU39_RS04960	COG0563	adenylate kinase activity
KU39_RS04965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KU39_RS04970	COG2223	nitrite transmembrane transporter activity
KU39_RS04980	COG1278	Cold shock
KU39_RS04985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KU39_RS04990	COG0542	response to heat
KU39_RS04995	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KU39_RS05005	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS05015	COG0492	ferredoxin-NADP+ reductase activity
KU39_RS05020	COG1674	ftsk spoiiie
KU39_RS05035	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KU39_RS05040	COG1104	cysteine desulfurase activity
KU39_RS05050	COG0105	UTP biosynthetic process
KU39_RS05055	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KU39_RS05075	COG0124	histidyl-tRNA synthetase
KU39_RS05085	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KU39_RS05090	COG1160	GTP binding
KU39_RS05110	COG1192	Involved in chromosome partitioning
KU39_RS05120	COG0835	chemotaxis
KU39_RS05155	COG2201	protein-glutamate methylesterase activity
KU39_RS05165	COG1530	ribonuclease E activity
KU39_RS05175	COG2918	glutathione biosynthetic process
KU39_RS05180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU39_RS05185	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KU39_RS05190	COG0632	four-way junction helicase activity
KU39_RS05200	COG0811	peptide transport
KU39_RS05215	COG0823	Involved in the tonB-independent uptake of proteins
KU39_RS05225	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KU39_RS05230	COG0602	queuosine metabolic process
KU39_RS05250	COG1570	exodeoxyribonuclease VII activity
KU39_RS05255	COG1131	(ABC) transporter
KU39_RS05260	COG0842	Transport permease protein
KU39_RS05270	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS05280	COG0442	prolyl-tRNA aminoacylation
KU39_RS05285	COG3385	transposase activity
KU39_RS05310	COG3385	transposase activity
KU39_RS05345	COG3385	transposase activity
KU39_RS05350	COG2204	response regulator
KU39_RS05370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KU39_RS05375	COG0616	signal peptide processing
KU39_RS05380	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KU39_RS05450	COG1012	belongs to the aldehyde dehydrogenase family
KU39_RS05460	COG0784	Response regulator, receiver
KU39_RS05460	COG5002	protein histidine kinase activity
KU39_RS05460	COG2205	protein histidine kinase activity
KU39_RS05475	COG2801	Transposase and inactivated derivatives
KU39_RS05490	COG0183	Belongs to the thiolase family
KU39_RS05495	COG1024	Enoyl-CoA hydratase
KU39_RS05495	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU39_RS05510	COG1472	Belongs to the glycosyl hydrolase 3 family
KU39_RS05515	COG0668	transmembrane transport
KU39_RS05520	COG0598	Magnesium transport protein CorA
KU39_RS05525	COG0318	PFAM AMP-dependent synthetase and ligase
KU39_RS05535	COG0460	homoserine dehydrogenase
KU39_RS05535	COG0527	aspartate kinase activity
KU39_RS05545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KU39_RS05560	COG2801	Transposase and inactivated derivatives
KU39_RS05565	COG2801	Transposase and inactivated derivatives
KU39_RS05570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KU39_RS05575	COG2814	Major facilitator Superfamily
KU39_RS05580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KU39_RS05675	COG1181	Belongs to the D-alanine--D-alanine ligase family
KU39_RS05700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU39_RS05710	COG0564	pseudouridine synthase activity
KU39_RS05715	COG1335	isochorismatase
KU39_RS05720	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KU39_RS05750	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KU39_RS05775	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS05795	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS05805	COG0288	reversible hydration of carbon dioxide
KU39_RS05810	COG2814	Major facilitator Superfamily
KU39_RS05815	COG0525	valine-tRNA ligase activity
KU39_RS05825	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KU39_RS05830	COG0795	lipopolysaccharide-transporting ATPase activity
KU39_RS05840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KU39_RS05845	COG0343	queuine tRNA-ribosyltransferase activity
KU39_RS05850	COG1862	Preprotein translocase
KU39_RS05855	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KU39_RS05860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KU39_RS05875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KU39_RS05880	COG1876	peptidase activity
KU39_RS05885	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KU39_RS05895	COG1090	epimerase
KU39_RS05915	COG2801	Transposase and inactivated derivatives
KU39_RS05920	COG3385	transposase activity
KU39_RS05985	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KU39_RS05990	COG2894	cell division
KU39_RS05995	COG0850	regulation of cytokinetic process
KU39_RS06010	COG0733	neurotransmitter:sodium symporter activity
KU39_RS06015	COG0708	Exodeoxyribonuclease III
KU39_RS06050	COG3385	transposase activity
KU39_RS06080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KU39_RS06085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KU39_RS06090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KU39_RS06105	COG0326	Molecular chaperone. Has ATPase activity
KU39_RS06155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KU39_RS06155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KU39_RS06165	COG0488	(ABC) transporter
KU39_RS06180	COG3385	transposase activity
KU39_RS06240	COG2801	Transposase and inactivated derivatives
KU39_RS06250	COG3385	transposase activity
KU39_RS06255	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS06290	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KU39_RS06290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KU39_RS06300	COG3655	Transcriptional regulator
KU39_RS06315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KU39_RS06320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU39_RS06330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KU39_RS06370	COG2805	Type II/IV secretion system protein
KU39_RS06465	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KU39_RS06470	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KU39_RS06475	COG1294	oxidase, subunit
KU39_RS06485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU39_RS06485	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KU39_RS06515	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KU39_RS06530	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KU39_RS06560	COG0730	response to heat
KU39_RS06565	COG1671	Belongs to the UPF0178 family
KU39_RS06570	COG0688	phosphatidylethanolamine metabolic process
KU39_RS06575	COG1162	GTPase activity
KU39_RS06585	COG0802	atpase or kinase
KU39_RS06595	COG0783	Belongs to the Dps family
KU39_RS06605	COG0753	catalase activity
KU39_RS06610	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KU39_RS06620	COG2801	Transposase and inactivated derivatives
KU39_RS06630	COG3385	transposase activity
KU39_RS06640	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS06665	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS06675	COG0488	(ABC) transporter
KU39_RS06685	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KU39_RS06695	COG0101	tRNA pseudouridine synthase activity
KU39_RS06700	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KU39_RS06705	COG0285	dihydrofolate synthase activity
KU39_RS06710	COG1286	toxin biosynthetic process
KU39_RS06725	COG0405	Gamma-glutamyltransferase
KU39_RS06740	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KU39_RS06750	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KU39_RS06760	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KU39_RS06765	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KU39_RS06800	COG0531	amino acid
KU39_RS06805	COG0584	glycerophosphoryl diester phosphodiesterase
KU39_RS06810	COG2271	Major facilitator Superfamily
KU39_RS06815	COG1923	regulation of RNA biosynthetic process
KU39_RS06820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KU39_RS06825	COG0330	HflC and HflK could
KU39_RS06830	COG0330	HflC and HflK could
KU39_RS06835	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KU39_RS06840	COG2252	PERMEase
KU39_RS06845	COG0557	exoribonuclease II activity
KU39_RS06850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU39_RS06875	COG1120	ATPase activity
KU39_RS06880	COG0019	diaminopimelate decarboxylase activity
KU39_RS06890	COG2814	Major facilitator Superfamily
KU39_RS06900	COG1181	Belongs to the D-alanine--D-alanine ligase family
KU39_RS06905	COG4772	TonB-dependent receptor
KU39_RS06910	COG0811	peptide transport
KU39_RS06930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KU39_RS06945	COG3385	transposase activity
KU39_RS06960	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU39_RS06960	COG1902	pentaerythritol trinitrate reductase activity
KU39_RS06970	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KU39_RS06980	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KU39_RS06985	COG0336	Belongs to the RNA methyltransferase TrmD family
KU39_RS06990	COG0335	large ribosomal subunit rRNA binding
KU39_RS07020	COG2801	Transposase and inactivated derivatives
KU39_RS07040	COG2801	Transposase and inactivated derivatives
KU39_RS07045	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS07070	COG3385	transposase activity
KU39_RS07080	COG2801	Transposase and inactivated derivatives
KU39_RS07115	COG3385	transposase activity
KU39_RS07125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KU39_RS07130	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KU39_RS07135	COG0504	CTP synthase activity
KU39_RS07140	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KU39_RS07145	COG0148	phosphopyruvate hydratase activity
KU39_RS07150	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KU39_RS07155	COG0585	pseudouridine synthase activity
KU39_RS07160	COG0531	amino acid
KU39_RS07165	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KU39_RS07170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KU39_RS07185	COG3385	transposase activity
KU39_RS07225	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS07230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KU39_RS07235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KU39_RS07240	COG1845	cytochrome c oxidase, subunit III
KU39_RS07245	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KU39_RS07295	COG3104	oligopeptide transport
KU39_RS07310	COG2814	Major facilitator Superfamily
KU39_RS07315	COG0814	amino acid
KU39_RS07325	COG2840	Smr protein MutS2
KU39_RS07330	COG2890	protein-(glutamine-N5) methyltransferase activity
KU39_RS07335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KU39_RS07340	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KU39_RS07370	COG0095	Lipoate-protein ligase
KU39_RS07375	COG0095	Lipoate-protein ligase
KU39_RS07380	COG0739	heme binding
KU39_RS07390	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KU39_RS07400	COG0488	(ABC) transporter
KU39_RS07410	COG1388	LysM domain
KU39_RS07410	COG0741	lytic transglycosylase activity
KU39_RS07445	COG1987	bacterial-type flagellum assembly
KU39_RS07460	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KU39_RS07485	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KU39_RS07490	COG0784	Response regulator, receiver
KU39_RS07490	COG0643	Histidine kinase
KU39_RS07490	COG2198	Histidine kinase
KU39_RS07510	COG1959	2 iron, 2 sulfur cluster binding
KU39_RS07515	COG0719	Fe-S assembly protein
KU39_RS07520	COG0396	ATPase activity
KU39_RS07525	COG0719	Fe-S assembly protein
KU39_RS07530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KU39_RS07535	COG0316	Belongs to the HesB IscA family
KU39_RS07550	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS07560	COG2963	transposase activity
KU39_RS07575	COG0572	uridine kinase
KU39_RS07580	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KU39_RS07620	COG0387	Pfam Sodium calcium exchanger
KU39_RS07625	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS07630	COG0686	Belongs to the AlaDH PNT family
KU39_RS07670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU39_RS07675	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KU39_RS07700	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS07715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU39_RS07720	COG0477	Major facilitator Superfamily
KU39_RS07770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KU39_RS07795	COG2801	Transposase and inactivated derivatives
KU39_RS07825	COG2801	Transposase and inactivated derivatives
KU39_RS07835	COG4974	Belongs to the 'phage' integrase family
KU39_RS07850	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS07855	COG3177	Filamentation induced by cAMP protein fic
KU39_RS07865	COG0475	glutathione-regulated potassium exporter activity
KU39_RS07865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU39_RS07885	COG2801	Transposase and inactivated derivatives
KU39_RS07890	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS07895	COG1115	amino acid carrier protein
KU39_RS07900	COG0740	serine-type endopeptidase activity
KU39_RS07910	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KU39_RS07920	COG1663	tetraacyldisaccharide 4'-kinase activity
KU39_RS07925	COG1132	(ABC) transporter
KU39_RS07930	COG0848	biopolymer transport protein
KU39_RS07935	COG0811	peptide transport
KU39_RS07945	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS07960	COG2801	Transposase and inactivated derivatives
KU39_RS07980	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS07985	COG0658	competence protein
KU39_RS07985	COG2333	competence protein COMEC
KU39_RS08000	COG0583	DNA-binding transcription factor activity
KU39_RS08005	COG0515	serine threonine protein kinase
KU39_RS08005	COG4991	sh3 domain protein
KU39_RS08005	COG3064	Membrane
KU39_RS08025	COG0513	Belongs to the DEAD box helicase family
KU39_RS08030	COG2866	Carboxypeptidase
KU39_RS08035	COG2095	MarC family integral membrane protein
KU39_RS08055	COG1280	lysine exporter protein (LysE YggA)
KU39_RS08075	COG2815	serine threonine protein kinase
KU39_RS08075	COG0515	serine threonine protein kinase
KU39_RS08095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KU39_RS08100	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KU39_RS08105	COG2814	Major facilitator Superfamily
KU39_RS08135	COG2801	Transposase and inactivated derivatives
KU39_RS08150	COG3676	manually curated
KU39_RS08165	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS08200	COG3064	Membrane
KU39_RS08200	COG4991	sh3 domain protein
KU39_RS08200	COG0515	serine threonine protein kinase
KU39_RS08210	COG0659	secondary active sulfate transmembrane transporter activity
KU39_RS08215	COG1054	Belongs to the UPF0176 family
KU39_RS08225	COG0741	lytic transglycosylase activity
KU39_RS08230	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS08245	COG0513	Belongs to the DEAD box helicase family
KU39_RS08310	COG0590	tRNA wobble adenosine to inosine editing
KU39_RS08350	COG2801	Transposase and inactivated derivatives
KU39_RS08360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KU39_RS08360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KU39_RS08370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KU39_RS08370	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KU39_RS08385	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS08395	COG1294	oxidase, subunit
KU39_RS08430	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KU39_RS08470	COG3385	transposase activity
KU39_RS08490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KU39_RS08500	COG2801	Transposase and inactivated derivatives
KU39_RS08505	COG2801	Transposase and inactivated derivatives
KU39_RS08535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU39_RS08540	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU39_RS08545	COG0784	Response regulator, receiver
KU39_RS08545	COG0835	chemotaxis
KU39_RS08550	COG0596	Alpha beta hydrolase
KU39_RS08560	COG1643	Atp-dependent helicase
KU39_RS08575	COG2070	2-Nitropropane dioxygenase
KU39_RS08580	COG0604	alcohol dehydrogenase
KU39_RS08580	COG1028	Short-chain dehydrogenase reductase Sdr
KU39_RS08580	COG3321	synthase
KU39_RS08590	COG1028	Short-chain dehydrogenase reductase Sdr
KU39_RS08590	COG0604	alcohol dehydrogenase
KU39_RS08590	COG3321	synthase
KU39_RS08610	COG2963	transposase activity
KU39_RS08615	COG0784	Response regulator, receiver
KU39_RS08615	COG0835	chemotaxis
KU39_RS08630	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KU39_RS08630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KU39_RS08665	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KU39_RS08665	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KU39_RS08690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU39_RS08695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU39_RS08700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU39_RS08710	COG0729	surface antigen
KU39_RS08725	COG1376	ErfK ybiS ycfS ynhG family protein
KU39_RS08840	COG2801	Transposase and inactivated derivatives
KU39_RS08855	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS08860	COG3385	transposase activity
KU39_RS08885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU39_RS08890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU39_RS08895	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KU39_RS08930	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KU39_RS08945	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KU39_RS08950	COG2081	HI0933 family
KU39_RS08955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU39_RS08965	COG1024	Enoyl-CoA hydratase
KU39_RS08975	COG3501	Rhs element vgr protein
KU39_RS08990	COG1960	acyl-CoA dehydrogenase activity
KU39_RS08995	COG0183	Belongs to the thiolase family
KU39_RS09000	COG1024	Enoyl-CoA hydratase
KU39_RS09000	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU39_RS09025	COG2963	transposase activity
KU39_RS09060	COG2957	Belongs to the agmatine deiminase family
KU39_RS09065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU39_RS09075	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KU39_RS09110	COG0717	Belongs to the dCTP deaminase family
KU39_RS09120	COG1968	undecaprenyl-diphosphatase activity
KU39_RS09140	COG3385	transposase activity
KU39_RS09175	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS09210	COG0564	pseudouridine synthase activity
KU39_RS09265	COG4221	oxidoreductase activity
KU39_RS09270	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS09275	COG4221	oxidoreductase activity
KU39_RS09310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KU39_RS09325	COG2801	Transposase and inactivated derivatives
KU39_RS09445	COG1256	bacterial-type flagellum assembly
KU39_RS09445	COG4786	Flagellar basal body rod
KU39_RS09455	COG1706	bacterial-type flagellum-dependent cell motility
KU39_RS09465	COG4786	Flagellar basal body rod
KU39_RS09470	COG4787	bacterial-type flagellum-dependent cell motility
KU39_RS09475	COG1749	Flagellar hook protein flgE
KU39_RS09480	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KU39_RS09510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KU39_RS09525	COG3385	transposase activity
KU39_RS09535	COG2022	thiamine diphosphate biosynthetic process
KU39_RS09550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU39_RS09555	COG0531	amino acid
KU39_RS09580	COG2801	Transposase and inactivated derivatives
KU39_RS09610	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS09630	COG1393	Belongs to the ArsC family
KU39_RS09635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KU39_RS09640	COG2066	Belongs to the glutaminase family
KU39_RS09645	COG0736	holo-[acyl-carrier-protein] synthase activity
KU39_RS09650	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KU39_RS09655	COG1381	Involved in DNA repair and RecF pathway recombination
KU39_RS09675	COG0681	Belongs to the peptidase S26 family
KU39_RS09685	COG1595	DNA-templated transcription, initiation
KU39_RS09700	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KU39_RS09730	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS09735	COG2801	Transposase and inactivated derivatives
KU39_RS09780	COG0583	DNA-binding transcription factor activity
KU39_RS09785	COG1199	ATP-dependent helicase activity
KU39_RS09810	COG4520	surface antigen
KU39_RS09830	COG0305	Participates in initiation and elongation during chromosome replication
KU39_RS09835	COG0359	binds to the 23S rRNA
KU39_RS09840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KU39_RS09845	COG0360	Binds together with S18 to 16S ribosomal RNA
KU39_RS09860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KU39_RS09865	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KU39_RS09870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KU39_RS09875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KU39_RS09885	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KU39_RS09910	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS09915	COG2801	Transposase and inactivated derivatives
KU39_RS09950	COG3385	transposase activity
KU39_RS09965	COG1074	ATP-dependent DNA helicase activity
KU39_RS09975	COG2814	Major facilitator Superfamily
KU39_RS10020	COG2801	Transposase and inactivated derivatives
KU39_RS10050	COG1360	Flagellar Motor Protein
KU39_RS10055	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KU39_RS10060	COG0142	geranyltranstransferase activity
KU39_RS10065	COG1469	GTP cyclohydrolase I activity
KU39_RS10100	COG2801	Transposase and inactivated derivatives
KU39_RS10115	COG3385	transposase activity
KU39_RS10130	COG2963	transposase activity
KU39_RS10145	COG2801	Transposase and inactivated derivatives
KU39_RS10160	COG2801	Transposase and inactivated derivatives
KU39_RS10205	COG1366	Belongs to the anti-sigma-factor antagonist family
KU39_RS10220	COG2304	oxidoreductase activity
KU39_RS10225	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS10245	COG0714	Associated with various cellular activities
KU39_RS10250	COG0604	alcohol dehydrogenase
KU39_RS10285	COG0840	transmembrane signaling receptor activity
KU39_RS10305	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS10330	COG3385	transposase activity
KU39_RS10335	COG2801	Transposase and inactivated derivatives
KU39_RS10410	COG0189	ligase activity
KU39_RS10415	COG1131	(ABC) transporter
KU39_RS10475	COG0784	Response regulator, receiver
KU39_RS10475	COG0835	chemotaxis
KU39_RS10490	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS10510	COG2860	membrane
KU39_RS10520	COG2166	iron-sulfur cluster assembly
KU39_RS10535	COG2801	Transposase and inactivated derivatives
KU39_RS10565	COG2205	protein histidine kinase activity
KU39_RS10570	COG0745	RESPONSE REGULATOR receiver
KU39_RS10590	COG0424	maF-like protein
KU39_RS10605	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KU39_RS10610	COG2902	Dehydrogenase
KU39_RS10620	COG2766	serine protein kinase
KU39_RS10630	COG2719	SpoVR family
KU39_RS10640	COG1994	Peptidase M50
KU39_RS10655	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KU39_RS10670	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KU39_RS10670	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KU39_RS10680	COG1940	carbohydrate kinase activity
KU39_RS10685	COG1011	Hydrolase
KU39_RS10695	COG4178	(ABC) transporter
KU39_RS10705	COG1194	a g-specific adenine glycosylase
KU39_RS10710	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KU39_RS10720	COG2801	Transposase and inactivated derivatives
KU39_RS10725	COG2801	Transposase and inactivated derivatives
KU39_RS10775	COG3724	N-succinylarginine dihydrolase activity
KU39_RS10780	COG1012	belongs to the aldehyde dehydrogenase family
KU39_RS10790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KU39_RS10795	COG1607	acyl-coa hydrolase
KU39_RS10800	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KU39_RS10805	COG1561	YicC-like family, N-terminal region
KU39_RS10810	COG0194	GDP metabolic process
KU39_RS10815	COG1758	RNA polymerase activity
KU39_RS10820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU39_RS10845	COG0477	Major facilitator Superfamily
KU39_RS10850	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS10855	COG3385	transposase activity
KU39_RS10865	COG3385	transposase activity
KU39_RS10880	COG0477	Major facilitator Superfamily
KU39_RS10910	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KU39_RS10920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KU39_RS10935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU39_RS10935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU39_RS10940	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KU39_RS10945	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KU39_RS10950	COG0488	(ABC) transporter
KU39_RS10985	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS10995	COG0346	lactoylglutathione lyase activity
KU39_RS11000	COG1555	photosystem II stabilization
KU39_RS11015	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KU39_RS11020	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KU39_RS11030	COG3676	manually curated
KU39_RS11035	COG0402	S-adenosylhomocysteine deaminase activity
KU39_RS11060	COG0798	PFAM Bile acid sodium symporter
KU39_RS11065	COG3385	transposase activity
KU39_RS11090	COG0505	Belongs to the CarA family
KU39_RS11095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KU39_RS11100	COG0540	Belongs to the ATCase OTCase family
KU39_RS11105	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KU39_RS11115	COG0542	response to heat
KU39_RS11120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU39_RS11150	COG2814	Major facilitator Superfamily
KU39_RS11155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU39_RS11155	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU39_RS11160	COG2878	Part of a membrane complex involved in electron transport
KU39_RS11165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KU39_RS11205	COG0670	Belongs to the BI1 family
KU39_RS11210	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KU39_RS11225	COG2920	part of a sulfur-relay system
KU39_RS11230	COG2095	MarC family integral membrane protein
KU39_RS11265	COG0742	ribosomal rna small subunit methyltransferase
KU39_RS11315	COG2971	BadF BadG BcrA BcrD
KU39_RS11320	COG2814	Major facilitator Superfamily
KU39_RS11325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KU39_RS11330	COG1959	2 iron, 2 sulfur cluster binding
KU39_RS11335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU39_RS11335	COG1017	nitric oxide dioxygenase activity
KU39_RS11340	COG2197	response regulator
KU39_RS11350	COG2962	Rard protein
KU39_RS11370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KU39_RS11375	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KU39_RS11385	COG0628	permease
KU39_RS11390	COG2076	Multidrug Resistance protein
KU39_RS11410	COG1619	proteins homologs of microcin C7 resistance protein MccF
KU39_RS11420	COG3385	transposase activity
KU39_RS11430	COG2963	transposase activity
KU39_RS11470	COG3385	transposase activity
KU39_RS11495	COG2814	Major facilitator Superfamily
KU39_RS11500	COG2890	protein-(glutamine-N5) methyltransferase activity
KU39_RS11505	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KU39_RS11510	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KU39_RS11530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KU39_RS11535	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KU39_RS11540	COG0193	aminoacyl-tRNA hydrolase activity
KU39_RS11550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KU39_RS11555	COG2226	methyltransferase
KU39_RS11580	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS11595	COG3385	transposase activity
KU39_RS11615	COG3104	oligopeptide transport
KU39_RS11625	COG2801	Transposase and inactivated derivatives
KU39_RS11630	COG3104	oligopeptide transport
KU39_RS11640	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KU39_RS11645	COG0509	glycine decarboxylation via glycine cleavage system
KU39_RS11650	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KU39_RS11655	COG1519	Transferase
KU39_RS11660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KU39_RS11665	COG1215	transferase activity, transferring glycosyl groups
KU39_RS11675	COG0859	PFAM glycosyl transferase family 9
KU39_RS11690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KU39_RS11695	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KU39_RS11700	COG3161	chorismate lyase activity
KU39_RS11720	COG0247	lactate metabolic process
KU39_RS11720	COG0277	FAD linked oxidase domain protein
KU39_RS11725	COG2827	Endonuclease containing a URI domain
KU39_RS11750	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS11785	COG3385	transposase activity
KU39_RS11795	COG2801	Transposase and inactivated derivatives
KU39_RS11800	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS11815	COG2963	transposase activity
KU39_RS11820	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KU39_RS11825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KU39_RS11830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KU39_RS11835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KU39_RS11840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KU39_RS11845	COG1028	Short-chain dehydrogenase reductase Sdr
KU39_RS11850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KU39_RS11855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KU39_RS11860	COG0416	fatty acid biosynthetic process
KU39_RS11865	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KU39_RS11875	COG2823	Periplasmic or secreted lipoprotein
KU39_RS11880	COG3243	poly(R)-hydroxyalkanoic acid synthase
KU39_RS11900	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KU39_RS11935	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KU39_RS11940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KU39_RS11945	COG1127	ABC transporter
KU39_RS11950	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KU39_RS11950	COG0517	IMP dehydrogenase activity
KU39_RS11965	COG1137	ATPase activity
KU39_RS11980	COG1660	Displays ATPase and GTPase activities
KU39_RS11995	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KU39_RS12005	COG0784	Response regulator, receiver
KU39_RS12005	COG0835	chemotaxis
KU39_RS12095	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KU39_RS12100	COG0512	Glutamine amidotransferase of anthranilate synthase
KU39_RS12105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KU39_RS12120	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KU39_RS12140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU39_RS12145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KU39_RS12150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KU39_RS12155	COG2967	ApaG domain
KU39_RS12160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KU39_RS12170	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS12180	COG3385	transposase activity
KU39_RS12200	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KU39_RS12205	COG4535	Mg2 and Co2 transporter CorC
KU39_RS12215	COG1702	phosphate starvation-inducible protein PhoH
KU39_RS12220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KU39_RS12225	COG0617	tRNA 3'-terminal CCA addition
KU39_RS12230	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS12265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KU39_RS12270	COG0724	RNA recognition motif
KU39_RS12275	COG4608	Belongs to the ABC transporter superfamily
KU39_RS12285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU39_RS12290	COG0601	transmembrane transport
KU39_RS12295	COG0747	negative chemotaxis
KU39_RS12300	COG0527	aspartate kinase activity
KU39_RS12305	COG0019	diaminopimelate decarboxylase activity
KU39_RS12325	COG0463	Glycosyl transferase, family 2
KU39_RS12330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KU39_RS12335	COG2076	Multidrug Resistance protein
KU39_RS12340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KU39_RS12345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU39_RS12355	COG0745	RESPONSE REGULATOR receiver
KU39_RS12410	COG3385	transposase activity
KU39_RS12415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU39_RS12435	COG0328	RNA-DNA hybrid ribonuclease activity
KU39_RS12460	COG3385	transposase activity
KU39_RS12470	COG4166	transmembrane transport
KU39_RS12505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KU39_RS12510	COG0813	purine-nucleoside phosphorylase activity
KU39_RS12520	COG0167	dihydroorotate dehydrogenase activity
KU39_RS12530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU39_RS12530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KU39_RS12560	COG2217	Heavy metal translocating P-type atpase
KU39_RS12565	COG2217	Heavy metal translocating P-type atpase
KU39_RS12570	COG2217	Heavy metal translocating P-type atpase
KU39_RS12595	COG0242	peptide deformylase activity
KU39_RS12605	COG0784	Response regulator, receiver
KU39_RS12605	COG0835	chemotaxis
KU39_RS12615	COG0425	Belongs to the sulfur carrier protein TusA family
KU39_RS12800	COG2805	Type II/IV secretion system protein
KU39_RS12845	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KU39_RS12865	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS12875	COG3385	transposase activity
KU39_RS12885	COG0071	Belongs to the small heat shock protein (HSP20) family
KU39_RS12890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KU39_RS12910	COG3385	transposase activity
KU39_RS12920	COG1131	(ABC) transporter
KU39_RS12930	COG4206	TonB-dependent receptor
KU39_RS12950	COG1280	lysine exporter protein (LysE YggA)
KU39_RS12955	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KU39_RS12985	COG3385	transposase activity
KU39_RS12995	COG3012	SEC-C Motif Domain Protein
KU39_RS13005	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KU39_RS13010	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KU39_RS13020	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KU39_RS13025	COG0235	Class ii aldolase
KU39_RS13030	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KU39_RS13050	COG0306	phosphate transporter
KU39_RS13055	COG1392	Phosphate transport regulator
KU39_RS13090	COG3385	transposase activity
KU39_RS13105	COG0833	amino acid
KU39_RS13110	COG0114	fumarate hydratase activity
KU39_RS13130	COG3385	transposase activity
KU39_RS13135	COG3385	transposase activity
KU39_RS13250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KU39_RS13305	COG0586	Pfam SNARE associated Golgi protein
KU39_RS13310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU39_RS13325	COG3385	transposase activity
KU39_RS13335	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS13340	COG1063	alcohol dehydrogenase
KU39_RS13345	COG0156	8-amino-7-oxononanoate synthase activity
KU39_RS13385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU39_RS13400	COG0596	Alpha beta hydrolase
KU39_RS13415	COG1040	competence protein
KU39_RS13440	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KU39_RS13440	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KU39_RS13445	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KU39_RS13460	COG1028	Short-chain dehydrogenase reductase Sdr
KU39_RS13485	COG0561	phosphatase activity
KU39_RS13495	COG3385	transposase activity
KU39_RS13520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU39_RS13530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KU39_RS13545	COG0776	regulation of translation
KU39_RS13550	COG0745	RESPONSE REGULATOR receiver
KU39_RS13565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU39_RS13570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU39_RS13575	COG3079	Belongs to the UPF0149 family
KU39_RS13590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KU39_RS13610	COG0494	nUDIX hydrolase
KU39_RS13615	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KU39_RS13635	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS13665	COG3385	transposase activity
KU39_RS13675	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU39_RS13680	COG0321	lipoyl(octanoyl) transferase activity
KU39_RS13690	COG1686	Belongs to the peptidase S11 family
KU39_RS13700	COG2951	lytic endotransglycosylase activity
KU39_RS13705	COG0772	Belongs to the SEDS family
KU39_RS13710	COG0768	penicillin binding
KU39_RS13715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KU39_RS13725	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KU39_RS13730	COG1466	dna polymerase III delta subunit
KU39_RS13740	COG0495	leucyl-tRNA aminoacylation
KU39_RS13765	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KU39_RS13785	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KU39_RS13790	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KU39_RS13800	COG0018	arginyl-trna synthetase
KU39_RS13805	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KU39_RS13830	COG0180	Tryptophanyl-tRNA synthetase
KU39_RS13835	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KU39_RS13840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KU39_RS13845	COG1253	flavin adenine dinucleotide binding
KU39_RS13860	COG2801	Transposase and inactivated derivatives
KU39_RS13865	COG3385	transposase activity
KU39_RS13885	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KU39_RS13890	COG2814	Major facilitator Superfamily
KU39_RS13895	COG0203	ribosomal protein L17
KU39_RS13900	COG0202	RNA polymerase activity
KU39_RS13905	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KU39_RS13910	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KU39_RS13915	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KU39_RS13925	COG0200	Binds to the 23S rRNA
KU39_RS13935	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KU39_RS13940	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KU39_RS13945	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KU39_RS13950	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KU39_RS13955	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KU39_RS13965	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KU39_RS13975	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KU39_RS13980	COG0255	Belongs to the universal ribosomal protein uL29 family
KU39_RS13985	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KU39_RS13990	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KU39_RS13995	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KU39_RS14000	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KU39_RS14005	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KU39_RS14010	COG0089	rRNA binding
KU39_RS14015	COG0088	Forms part of the polypeptide exit tunnel
KU39_RS14020	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KU39_RS14025	COG0051	transcription antitermination factor activity, RNA binding
KU39_RS14030	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KU39_RS14035	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KU39_RS14040	COG0049	tRNA binding
KU39_RS14045	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KU39_RS14055	COG0085	RNA polymerase activity
KU39_RS14060	COG0222	ribosome binding
KU39_RS14065	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KU39_RS14070	COG0081	regulation of translation
KU39_RS14075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KU39_RS14085	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KU39_RS14120	COG1459	type II secretion system
KU39_RS14140	COG0237	dephospho-CoA kinase activity
KU39_RS14145	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KU39_RS14150	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KU39_RS14160	COG3130	regulation of translation
KU39_RS14165	COG0477	Major facilitator Superfamily
KU39_RS14175	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KU39_RS14180	COG0484	heat shock protein binding
KU39_RS14185	COG0443	Heat shock 70 kDa protein
KU39_RS14190	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KU39_RS14195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KU39_RS14200	COG0497	DNA recombination
KU39_RS14210	COG0735	belongs to the Fur family
KU39_RS14225	COG2914	Belongs to the UPF0125 (RnfH) family
KU39_RS14230	COG2867	negative regulation of translational initiation
KU39_RS14235	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KU39_RS14240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KU39_RS14250	COG2066	Belongs to the glutaminase family
KU39_RS14260	COG1490	D-aminoacyl-tRNA deacylase activity
KU39_RS14270	COG2853	Lipoprotein
KU39_RS14280	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS14300	COG1028	Short-chain dehydrogenase reductase Sdr
KU39_RS14305	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS14310	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KU39_RS14340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KU39_RS14345	COG0617	tRNA 3'-terminal CCA addition
KU39_RS14350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KU39_RS14360	COG1028	Short-chain dehydrogenase reductase Sdr
KU39_RS14380	COG3243	poly(R)-hydroxyalkanoic acid synthase
KU39_RS14390	COG1185	polyribonucleotide nucleotidyltransferase activity
KU39_RS14395	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KU39_RS14400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KU39_RS14405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KU39_RS14410	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KU39_RS14415	COG0195	Participates in both transcription termination and antitermination
KU39_RS14415	COG2251	uridine kinase activity
KU39_RS14430	COG1007	ATP synthesis coupled electron transport
KU39_RS14445	COG0713	ATP synthesis coupled electron transport
KU39_RS14450	COG0839	Belongs to the complex I subunit 6 family
KU39_RS14455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KU39_RS14460	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KU39_RS14465	COG1034	ATP synthesis coupled electron transport
KU39_RS14465	COG1034	ATP synthesis coupled electron transport
KU39_RS14470	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KU39_RS14475	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KU39_RS14480	COG0649	NAD binding
KU39_RS14490	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KU39_RS14495	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KU39_RS14505	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KU39_RS14510	COG0149	triose-phosphate isomerase activity
KU39_RS14530	COG1435	thymidine kinase activity
KU39_RS14545	COG2363	Small membrane protein
KU39_RS14560	COG0494	nUDIX hydrolase
KU39_RS14580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KU39_RS14590	COG0254	rRNA binding
KU39_RS14595	COG0281	malic enzyme
KU39_RS14610	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS14625	COG3186	Phenylalanine-4-hydroxylase
KU39_RS14640	COG0625	glutathione transferase activity
KU39_RS14645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KU39_RS14655	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KU39_RS14660	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KU39_RS14660	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KU39_RS14665	COG0708	Exodeoxyribonuclease III
KU39_RS14670	COG0330	HflC and HflK could
KU39_RS14675	COG1585	Membrane protein implicated in regulation of membrane protease activity
KU39_RS14700	COG3385	transposase activity
KU39_RS14720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KU39_RS14725	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KU39_RS14730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KU39_RS14750	COG1217	gtp-binding protein TYPA
KU39_RS14785	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KU39_RS14840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KU39_RS14860	COG0248	Ppx GppA phosphatase
KU39_RS14875	COG0531	amino acid
KU39_RS14880	COG0174	glutamine synthetase
KU39_RS14885	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KU39_RS14890	COG0668	transmembrane transport
KU39_RS14920	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KU39_RS14930	COG2988	succinylglutamate desuccinylase activity
KU39_RS14955	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS14960	COG2271	Major facilitator Superfamily
KU39_RS14965	COG2814	Major facilitator Superfamily
KU39_RS14970	COG0583	DNA-binding transcription factor activity
KU39_RS14980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KU39_RS14985	COG4796	Type ii and iii secretion system protein
KU39_RS15035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU39_RS15040	COG0017	Asparaginyl-tRNA synthetase
KU39_RS15045	COG4962	Type ii secretion system protein e
KU39_RS15070	COG3504	Conjugal transfer protein
KU39_RS15080	COG3451	type IV secretory pathway VirB4
KU39_RS15115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU39_RS15130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU39_RS15135	COG0606	chelatase, subunit chli
KU39_RS15145	COG0347	Belongs to the P(II) protein family
KU39_RS15150	COG1166	arginine decarboxylase activity
KU39_RS15160	COG0463	Glycosyl transferase, family 2
KU39_RS15165	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KU39_RS15175	COG0133	tryptophan synthase activity
KU39_RS15185	COG0134	indole-3-glycerol-phosphate synthase activity
KU39_RS15190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KU39_RS15195	COG0512	Glutamine amidotransferase of anthranilate synthase
KU39_RS15195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KU39_RS15230	COG0450	alkyl hydroperoxide reductase
KU39_RS15255	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS15260	COG3385	transposase activity
KU39_RS15265	COG3385	transposase activity
KU39_RS15300	COG0752	glycyl-tRNA synthetase alpha subunit
KU39_RS15310	COG1607	acyl-coa hydrolase
KU39_RS15315	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KU39_RS15340	COG2828	Protein conserved in bacteria
KU39_RS15345	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KU39_RS15350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KU39_RS15355	COG0569	domain protein
KU39_RS15360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KU39_RS15365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KU39_RS15370	COG0242	peptide deformylase activity
KU39_RS15375	COG0758	DNA mediated transformation
KU39_RS15380	COG2922	Belongs to the Smg family
KU39_RS15390	COG0009	L-threonylcarbamoyladenylate synthase
KU39_RS15395	COG0408	coproporphyrinogen oxidase activity
KU39_RS15405	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS15425	COG2826	transposase and inactivated derivatives, IS30 family
KU39_RS15440	COG3385	transposase activity
KU39_RS15465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU39_RS15475	COG0793	Belongs to the peptidase S41A family
KU39_RS15485	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KU39_RS15495	COG3385	transposase activity
KU39_RS15520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KU39_RS15520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KU39_RS15525	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KU39_RS15535	COG3227	Zinc metalloprotease (Elastase)
KU39_RS15550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KU39_RS15550	COG0456	acetyltransferase
KU39_RS15590	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KU39_RS15595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KU39_RS15605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KU39_RS15610	COG1181	Belongs to the D-alanine--D-alanine ligase family
KU39_RS15615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KU39_RS15620	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KU39_RS15625	COG0772	Belongs to the SEDS family
KU39_RS15630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KU39_RS15635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KU39_RS15640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KU39_RS15645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KU39_RS15660	COG0275	rRNA processing
KU39_RS15665	COG2983	Belongs to the UPF0260 family
KU39_RS15685	COG0187	DNA topoisomerase II activity
KU39_RS15695	COG0592	DNA-directed DNA polymerase activity
KU39_RS15700	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KU39_RS15715	COG0706	membrane insertase activity
KU39_RS16125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KU39_RS16320	COG0706	membrane insertase activity
KU39_RS16325	COG0706	membrane insertase activity
KU39_RS16330	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KU39_RS16410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KU39_RS16415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KU39_RS16420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KU39_RS16500	COG3385	transposase activity
KU39_RS16905	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KU39_RS17280	COG0210	DNA helicase
KU39_RS17430	COG0356	it plays a direct role in the translocation of protons across the membrane
KU39_RS17465	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KU39_RS17470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KU39_RS17480	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain