locus-tag	class	description
AVI51_RS00020	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS00035	COG0358	DNA primase activity
AVI51_RS00040	COG1610	YqeY-like protein
AVI51_RS00045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AVI51_RS00050	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AVI51_RS00055	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AVI51_RS00085	COG0259	pyridoxamine-phosphate oxidase activity
AVI51_RS00090	COG0589	response to stress
AVI51_RS00100	COG1228	amidohydrolase
AVI51_RS00110	COG2986	histidine ammonia-lyase
AVI51_RS00125	COG3335	DDE superfamily endonuclease
AVI51_RS00150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AVI51_RS00155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVI51_RS00160	COG3956	TIGRFAM MazG family protein
AVI51_RS00170	COG3335	DDE superfamily endonuclease
AVI51_RS00180	COG0563	adenylate kinase activity
AVI51_RS00185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVI51_RS00190	COG2223	nitrite transmembrane transporter activity
AVI51_RS00205	COG1278	Cold shock
AVI51_RS00210	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVI51_RS00215	COG0542	response to heat
AVI51_RS00220	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AVI51_RS00235	COG0492	ferredoxin-NADP+ reductase activity
AVI51_RS00240	COG1674	ftsk spoiiie
AVI51_RS00245	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AVI51_RS00265	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS00275	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AVI51_RS00280	COG1104	cysteine desulfurase activity
AVI51_RS00290	COG0105	UTP biosynthetic process
AVI51_RS00295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AVI51_RS00315	COG0124	histidyl-tRNA synthetase
AVI51_RS00325	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVI51_RS00330	COG1160	GTP binding
AVI51_RS00335	COG1192	Involved in chromosome partitioning
AVI51_RS00345	COG0835	chemotaxis
AVI51_RS00365	COG2201	protein-glutamate methylesterase activity
AVI51_RS00375	COG1530	ribonuclease E activity
AVI51_RS00385	COG2918	glutathione biosynthetic process
AVI51_RS00390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVI51_RS00395	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AVI51_RS00400	COG0632	four-way junction helicase activity
AVI51_RS00410	COG0811	peptide transport
AVI51_RS00425	COG0823	Involved in the tonB-independent uptake of proteins
AVI51_RS00430	COG2885	chlorophyll binding
AVI51_RS00435	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AVI51_RS00440	COG0602	queuosine metabolic process
AVI51_RS00460	COG1570	exodeoxyribonuclease VII activity
AVI51_RS00465	COG1131	(ABC) transporter
AVI51_RS00470	COG0842	Transport permease protein
AVI51_RS00485	COG0442	prolyl-tRNA aminoacylation
AVI51_RS00520	COG3335	DDE superfamily endonuclease
AVI51_RS00530	COG3335	DDE superfamily endonuclease
AVI51_RS00540	COG3335	DDE superfamily endonuclease
AVI51_RS00545	COG2801	Transposase and inactivated derivatives
AVI51_RS00550	COG2963	transposase activity
AVI51_RS00565	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS00600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVI51_RS00605	COG0616	signal peptide processing
AVI51_RS00610	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AVI51_RS00635	COG1012	belongs to the aldehyde dehydrogenase family
AVI51_RS00645	COG0784	Response regulator, receiver
AVI51_RS00645	COG2205	protein histidine kinase activity
AVI51_RS00645	COG5002	protein histidine kinase activity
AVI51_RS00665	COG0183	Belongs to the thiolase family
AVI51_RS00685	COG1472	Belongs to the glycosyl hydrolase 3 family
AVI51_RS00690	COG0668	transmembrane transport
AVI51_RS00695	COG0598	Magnesium transport protein CorA
AVI51_RS00700	COG0318	PFAM AMP-dependent synthetase and ligase
AVI51_RS00715	COG3335	DDE superfamily endonuclease
AVI51_RS00730	COG3344	reverse transcriptase
AVI51_RS00740	COG2963	transposase activity
AVI51_RS00790	COG0460	homoserine dehydrogenase
AVI51_RS00790	COG0527	aspartate kinase activity
AVI51_RS00800	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AVI51_RS00820	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AVI51_RS00825	COG2814	Major facilitator Superfamily
AVI51_RS00830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVI51_RS00920	COG3335	DDE superfamily endonuclease
AVI51_RS00940	COG2814	Major facilitator Superfamily
AVI51_RS00950	COG1074	ATP-dependent DNA helicase activity
AVI51_RS00955	COG2801	Transposase and inactivated derivatives
AVI51_RS00970	COG2801	Transposase and inactivated derivatives
AVI51_RS00975	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS00995	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS01050	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AVI51_RS01055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AVI51_RS01060	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AVI51_RS01065	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AVI51_RS01080	COG0360	Binds together with S18 to 16S ribosomal RNA
AVI51_RS01085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AVI51_RS01090	COG0359	binds to the 23S rRNA
AVI51_RS01095	COG0305	Participates in initiation and elongation during chromosome replication
AVI51_RS01135	COG1199	ATP-dependent helicase activity
AVI51_RS01140	COG0583	DNA-binding transcription factor activity
AVI51_RS01190	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AVI51_RS01205	COG1595	DNA-templated transcription, initiation
AVI51_RS01210	COG0481	GTPase activity
AVI51_RS01215	COG0681	Belongs to the peptidase S26 family
AVI51_RS01220	COG0571	ribonuclease III activity
AVI51_RS01230	COG1381	Involved in DNA repair and RecF pathway recombination
AVI51_RS01235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AVI51_RS01240	COG0736	holo-[acyl-carrier-protein] synthase activity
AVI51_RS01255	COG2066	Belongs to the glutaminase family
AVI51_RS01265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVI51_RS01270	COG1393	Belongs to the ArsC family
AVI51_RS01300	COG3335	DDE superfamily endonuclease
AVI51_RS01315	COG0531	amino acid
AVI51_RS01320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVI51_RS01335	COG2022	thiamine diphosphate biosynthetic process
AVI51_RS01345	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS01365	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVI51_RS01385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVI51_RS01395	COG0564	pseudouridine synthase activity
AVI51_RS01405	COG1335	isochorismatase
AVI51_RS01410	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AVI51_RS01430	COG3335	DDE superfamily endonuclease
AVI51_RS01450	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AVI51_RS01470	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AVI51_RS01475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI51_RS01480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVI51_RS01580	COG1376	ErfK ybiS ycfS ynhG family protein
AVI51_RS01600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVI51_RS01605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI51_RS01610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVI51_RS01630	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AVI51_RS01630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVI51_RS01640	COG1393	Belongs to the ArsC family
AVI51_RS01645	COG0784	Response regulator, receiver
AVI51_RS01645	COG0835	chemotaxis
AVI51_RS01650	COG3321	synthase
AVI51_RS01650	COG1028	Short-chain dehydrogenase reductase Sdr
AVI51_RS01650	COG0604	alcohol dehydrogenase
AVI51_RS01705	COG1294	oxidase, subunit
AVI51_RS01710	COG3293	Transposase
AVI51_RS01720	COG2963	transposase activity
AVI51_RS01725	COG2801	Transposase and inactivated derivatives
AVI51_RS01730	COG3676	manually curated
AVI51_RS01790	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVI51_RS01790	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVI51_RS01800	COG4106	trans-aconitate 2-methyltransferase activity
AVI51_RS01820	COG0590	tRNA wobble adenosine to inosine editing
AVI51_RS01865	COG0513	Belongs to the DEAD box helicase family
AVI51_RS01880	COG0741	lytic transglycosylase activity
AVI51_RS01890	COG1054	Belongs to the UPF0176 family
AVI51_RS01895	COG0659	secondary active sulfate transmembrane transporter activity
AVI51_RS01900	COG2801	Transposase and inactivated derivatives
AVI51_RS01905	COG2963	transposase activity
AVI51_RS01910	COG0659	secondary active sulfate transmembrane transporter activity
AVI51_RS01960	COG0531	amino acid
AVI51_RS01990	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AVI51_RS02010	COG3047	cAMP biosynthetic process
AVI51_RS02020	COG3293	Transposase
AVI51_RS02030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AVI51_RS02035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVI51_RS02040	COG1845	cytochrome c oxidase, subunit III
AVI51_RS02045	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AVI51_RS02055	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS02085	COG3293	Transposase
AVI51_RS02090	COG3104	oligopeptide transport
AVI51_RS02100	COG3104	oligopeptide transport
AVI51_RS02110	COG2814	Major facilitator Superfamily
AVI51_RS02125	COG2801	Transposase and inactivated derivatives
AVI51_RS02130	COG2963	transposase activity
AVI51_RS02135	COG0814	amino acid
AVI51_RS02150	COG2890	protein-(glutamine-N5) methyltransferase activity
AVI51_RS02155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AVI51_RS02160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AVI51_RS02165	COG0346	lactoylglutathione lyase activity
AVI51_RS02180	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS02200	COG0095	Lipoate-protein ligase
AVI51_RS02205	COG0739	heme binding
AVI51_RS02215	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AVI51_RS02225	COG0488	(ABC) transporter
AVI51_RS02245	COG3335	DDE superfamily endonuclease
AVI51_RS02270	COG0741	lytic transglycosylase activity
AVI51_RS02270	COG1388	LysM domain
AVI51_RS02305	COG1987	bacterial-type flagellum assembly
AVI51_RS02345	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AVI51_RS02350	COG0643	Histidine kinase
AVI51_RS02350	COG0784	Response regulator, receiver
AVI51_RS02350	COG2198	Histidine kinase
AVI51_RS02370	COG1959	2 iron, 2 sulfur cluster binding
AVI51_RS02375	COG0719	Fe-S assembly protein
AVI51_RS02380	COG0396	ATPase activity
AVI51_RS02385	COG0719	Fe-S assembly protein
AVI51_RS02390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVI51_RS02395	COG0316	Belongs to the HesB IscA family
AVI51_RS02400	COG2151	metal-sulfur cluster biosynthetic enzyme
AVI51_RS02410	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS02425	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS02435	COG3335	DDE superfamily endonuclease
AVI51_RS02450	COG2801	Transposase and inactivated derivatives
AVI51_RS02465	COG0572	uridine kinase
AVI51_RS02470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AVI51_RS02510	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS02520	COG2814	Major facilitator Superfamily
AVI51_RS02525	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AVI51_RS02530	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AVI51_RS02590	COG3293	Transposase
AVI51_RS02605	COG2095	MarC family integral membrane protein
AVI51_RS02610	COG2866	Carboxypeptidase
AVI51_RS02615	COG0513	Belongs to the DEAD box helicase family
AVI51_RS02625	COG4991	sh3 domain protein
AVI51_RS02625	COG0515	serine threonine protein kinase
AVI51_RS02625	COG3064	Membrane
AVI51_RS02645	COG3335	DDE superfamily endonuclease
AVI51_RS02660	COG2963	transposase activity
AVI51_RS02695	COG2963	transposase activity
AVI51_RS02700	COG3676	manually curated
AVI51_RS02710	COG3335	DDE superfamily endonuclease
AVI51_RS02715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVI51_RS02720	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AVI51_RS02725	COG0504	CTP synthase activity
AVI51_RS02730	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AVI51_RS02735	COG0148	phosphopyruvate hydratase activity
AVI51_RS02740	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AVI51_RS02745	COG0585	pseudouridine synthase activity
AVI51_RS02750	COG0531	amino acid
AVI51_RS02755	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AVI51_RS02760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVI51_RS02765	COG2963	transposase activity
AVI51_RS02770	COG2801	Transposase and inactivated derivatives
AVI51_RS02800	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AVI51_RS02835	COG2963	transposase activity
AVI51_RS02840	COG2801	Transposase and inactivated derivatives
AVI51_RS02845	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS02860	COG3335	DDE superfamily endonuclease
AVI51_RS02875	COG1643	Atp-dependent helicase
AVI51_RS02890	COG0583	DNA-binding transcription factor activity
AVI51_RS02910	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS02925	COG0387	Pfam Sodium calcium exchanger
AVI51_RS02940	COG0686	Belongs to the AlaDH PNT family
AVI51_RS02965	COG3335	DDE superfamily endonuclease
AVI51_RS02975	COG2963	transposase activity
AVI51_RS02980	COG4232	protein-disulfide reductase activity
AVI51_RS03005	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS03015	COG0811	peptide transport
AVI51_RS03020	COG0848	biopolymer transport protein
AVI51_RS03025	COG1132	(ABC) transporter
AVI51_RS03030	COG1663	tetraacyldisaccharide 4'-kinase activity
AVI51_RS03040	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AVI51_RS03050	COG0740	serine-type endopeptidase activity
AVI51_RS03055	COG1115	amino acid carrier protein
AVI51_RS03060	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS03085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVI51_RS03085	COG0475	glutathione-regulated potassium exporter activity
AVI51_RS03090	COG3177	Filamentation induced by cAMP protein fic
AVI51_RS03145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVI51_RS03185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AVI51_RS03190	COG0477	Major facilitator Superfamily
AVI51_RS03195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AVI51_RS03220	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AVI51_RS03225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVI51_RS03265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVI51_RS03270	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVI51_RS03280	COG0835	chemotaxis
AVI51_RS03280	COG0784	Response regulator, receiver
AVI51_RS03315	COG0335	large ribosomal subunit rRNA binding
AVI51_RS03320	COG0336	Belongs to the RNA methyltransferase TrmD family
AVI51_RS03325	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AVI51_RS03335	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AVI51_RS03345	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVI51_RS03345	COG1902	pentaerythritol trinitrate reductase activity
AVI51_RS03370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AVI51_RS03390	COG0811	peptide transport
AVI51_RS03395	COG4772	TonB-dependent receptor
AVI51_RS03400	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVI51_RS03420	COG0019	diaminopimelate decarboxylase activity
AVI51_RS03425	COG1120	ATPase activity
AVI51_RS03445	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS03460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVI51_RS03465	COG0557	exoribonuclease II activity
AVI51_RS03470	COG2252	PERMEase
AVI51_RS03475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AVI51_RS03480	COG0330	HflC and HflK could
AVI51_RS03485	COG0330	HflC and HflK could
AVI51_RS03490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AVI51_RS03495	COG1923	regulation of RNA biosynthetic process
AVI51_RS03500	COG2271	Major facilitator Superfamily
AVI51_RS03505	COG0584	glycerophosphoryl diester phosphodiesterase
AVI51_RS03510	COG0531	amino acid
AVI51_RS03545	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AVI51_RS03550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AVI51_RS03560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AVI51_RS03570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AVI51_RS03600	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AVI51_RS03625	COG5433	transposase activity
AVI51_RS03650	COG2081	HI0933 family
AVI51_RS03655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVI51_RS03665	COG1024	Enoyl-CoA hydratase
AVI51_RS03675	COG3501	Rhs element vgr protein
AVI51_RS03700	COG1960	acyl-CoA dehydrogenase activity
AVI51_RS03705	COG0183	Belongs to the thiolase family
AVI51_RS03710	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVI51_RS03710	COG1024	Enoyl-CoA hydratase
AVI51_RS03725	COG3335	DDE superfamily endonuclease
AVI51_RS03750	COG3676	manually curated
AVI51_RS03765	COG2957	Belongs to the agmatine deiminase family
AVI51_RS03770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVI51_RS03780	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AVI51_RS03805	COG2963	transposase activity
AVI51_RS03825	COG2801	Transposase and inactivated derivatives
AVI51_RS03830	COG2963	transposase activity
AVI51_RS03835	COG3335	DDE superfamily endonuclease
AVI51_RS03840	COG0717	Belongs to the dCTP deaminase family
AVI51_RS03845	COG0489	protein tyrosine kinase activity
AVI51_RS03870	COG2963	transposase activity
AVI51_RS03900	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AVI51_RS03905	COG0753	catalase activity
AVI51_RS03910	COG0783	Belongs to the Dps family
AVI51_RS03915	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS03925	COG3335	DDE superfamily endonuclease
AVI51_RS03940	COG0802	atpase or kinase
AVI51_RS03950	COG1162	GTPase activity
AVI51_RS03955	COG0688	phosphatidylethanolamine metabolic process
AVI51_RS03960	COG1671	Belongs to the UPF0178 family
AVI51_RS03965	COG0730	response to heat
AVI51_RS03970	COG3335	DDE superfamily endonuclease
AVI51_RS03995	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AVI51_RS04000	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AVI51_RS04015	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AVI51_RS04080	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AVI51_RS04080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVI51_RS04095	COG1294	oxidase, subunit
AVI51_RS04100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AVI51_RS04105	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AVI51_RS04210	COG2805	Type II/IV secretion system protein
AVI51_RS04250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AVI51_RS04260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVI51_RS04265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AVI51_RS04280	COG3655	Transcriptional regulator
AVI51_RS04325	COG3335	DDE superfamily endonuclease
AVI51_RS04345	COG0564	pseudouridine synthase activity
AVI51_RS04380	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS04395	COG3335	DDE superfamily endonuclease
AVI51_RS04405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVI51_RS04445	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS04460	COG1090	epimerase
AVI51_RS04470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AVI51_RS04475	COG1876	peptidase activity
AVI51_RS04495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVI51_RS04500	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVI51_RS04505	COG1862	Preprotein translocase
AVI51_RS04510	COG0343	queuine tRNA-ribosyltransferase activity
AVI51_RS04515	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AVI51_RS04525	COG0795	lipopolysaccharide-transporting ATPase activity
AVI51_RS04530	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVI51_RS04540	COG0525	valine-tRNA ligase activity
AVI51_RS04545	COG2814	Major facilitator Superfamily
AVI51_RS04550	COG0288	reversible hydration of carbon dioxide
AVI51_RS04560	COG3344	reverse transcriptase
AVI51_RS04600	COG2963	transposase activity
AVI51_RS04605	COG0405	Gamma-glutamyltransferase
AVI51_RS04620	COG1286	toxin biosynthetic process
AVI51_RS04625	COG0285	dihydrofolate synthase activity
AVI51_RS04630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AVI51_RS04635	COG0101	tRNA pseudouridine synthase activity
AVI51_RS04645	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AVI51_RS04655	COG0488	(ABC) transporter
AVI51_RS04665	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS04710	COG3335	DDE superfamily endonuclease
AVI51_RS04720	COG3335	DDE superfamily endonuclease
AVI51_RS04725	COG3335	DDE superfamily endonuclease
AVI51_RS04740	COG0488	(ABC) transporter
AVI51_RS04750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI51_RS04750	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI51_RS04775	COG3335	DDE superfamily endonuclease
AVI51_RS04780	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS04815	COG0326	Molecular chaperone. Has ATPase activity
AVI51_RS04830	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVI51_RS04835	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AVI51_RS04870	COG0708	Exodeoxyribonuclease III
AVI51_RS04875	COG0733	neurotransmitter:sodium symporter activity
AVI51_RS04890	COG0850	regulation of cytokinetic process
AVI51_RS04895	COG2894	cell division
AVI51_RS04900	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AVI51_RS04905	COG4221	oxidoreductase activity
AVI51_RS04915	COG2963	transposase activity
AVI51_RS04950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVI51_RS04960	COG2963	transposase activity
AVI51_RS04975	COG3335	DDE superfamily endonuclease
AVI51_RS05020	COG1256	bacterial-type flagellum assembly
AVI51_RS05020	COG4786	Flagellar basal body rod
AVI51_RS05030	COG1706	bacterial-type flagellum-dependent cell motility
AVI51_RS05040	COG4786	Flagellar basal body rod
AVI51_RS05045	COG4787	bacterial-type flagellum-dependent cell motility
AVI51_RS05050	COG1749	Flagellar hook protein flgE
AVI51_RS05055	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AVI51_RS05085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AVI51_RS05090	COG0482	sulfurtransferase activity
AVI51_RS05130	COG1360	Flagellar Motor Protein
AVI51_RS05135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AVI51_RS05140	COG0142	geranyltranstransferase activity
AVI51_RS05145	COG1469	GTP cyclohydrolase I activity
AVI51_RS05165	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS05175	COG3335	DDE superfamily endonuclease
AVI51_RS05230	COG0604	alcohol dehydrogenase
AVI51_RS05235	COG0714	Associated with various cellular activities
AVI51_RS05250	COG2304	oxidoreductase activity
AVI51_RS05285	COG0840	transmembrane signaling receptor activity
AVI51_RS05310	COG3335	DDE superfamily endonuclease
AVI51_RS05335	COG3335	DDE superfamily endonuclease
AVI51_RS05345	COG2801	Transposase and inactivated derivatives
AVI51_RS05355	COG3335	DDE superfamily endonuclease
AVI51_RS05370	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS05450	COG0189	ligase activity
AVI51_RS05455	COG1131	(ABC) transporter
AVI51_RS05475	COG3293	Transposase
AVI51_RS05480	COG0835	chemotaxis
AVI51_RS05480	COG0784	Response regulator, receiver
AVI51_RS05505	COG3335	DDE superfamily endonuclease
AVI51_RS05510	COG2963	transposase activity
AVI51_RS05520	COG2860	membrane
AVI51_RS05530	COG2166	iron-sulfur cluster assembly
AVI51_RS05540	COG3293	Transposase
AVI51_RS05570	COG2205	protein histidine kinase activity
AVI51_RS05575	COG0745	RESPONSE REGULATOR receiver
AVI51_RS05595	COG0424	maF-like protein
AVI51_RS05600	COG0616	signal peptide processing
AVI51_RS05610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AVI51_RS05615	COG2902	Dehydrogenase
AVI51_RS05625	COG2766	serine protein kinase
AVI51_RS05635	COG2719	SpoVR family
AVI51_RS05655	COG1214	PFAM Peptidase M22, glycoprotease
AVI51_RS05685	COG3335	DDE superfamily endonuclease
AVI51_RS05705	COG2801	Transposase and inactivated derivatives
AVI51_RS05710	COG2963	transposase activity
AVI51_RS05735	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVI51_RS05735	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVI51_RS05745	COG1940	carbohydrate kinase activity
AVI51_RS05750	COG1011	Hydrolase
AVI51_RS05760	COG4178	(ABC) transporter
AVI51_RS05775	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AVI51_RS05785	COG1454	alcohol dehydrogenase
AVI51_RS05785	COG1012	belongs to the aldehyde dehydrogenase family
AVI51_RS05830	COG3724	N-succinylarginine dihydrolase activity
AVI51_RS05835	COG1012	belongs to the aldehyde dehydrogenase family
AVI51_RS05845	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AVI51_RS05850	COG1607	acyl-coa hydrolase
AVI51_RS05855	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AVI51_RS05860	COG1561	YicC-like family, N-terminal region
AVI51_RS05865	COG0194	GDP metabolic process
AVI51_RS05870	COG1758	RNA polymerase activity
AVI51_RS05875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVI51_RS05890	COG2963	transposase activity
AVI51_RS05950	COG0477	Major facilitator Superfamily
AVI51_RS05980	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AVI51_RS05990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVI51_RS06005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVI51_RS06005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVI51_RS06010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AVI51_RS06015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AVI51_RS06020	COG0488	(ABC) transporter
AVI51_RS06035	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS06060	COG0346	lactoylglutathione lyase activity
AVI51_RS06065	COG1555	photosystem II stabilization
AVI51_RS06080	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AVI51_RS06085	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AVI51_RS06105	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS06115	COG3293	Transposase
AVI51_RS06125	COG0402	S-adenosylhomocysteine deaminase activity
AVI51_RS06155	COG0798	PFAM Bile acid sodium symporter
AVI51_RS06165	COG3335	DDE superfamily endonuclease
AVI51_RS06205	COG0505	Belongs to the CarA family
AVI51_RS06210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AVI51_RS06215	COG0540	Belongs to the ATCase OTCase family
AVI51_RS06220	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AVI51_RS06230	COG0542	response to heat
AVI51_RS06235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVI51_RS06245	COG0295	cytidine deaminase activity
AVI51_RS06305	COG2814	Major facilitator Superfamily
AVI51_RS06315	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVI51_RS06315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVI51_RS06320	COG2878	Part of a membrane complex involved in electron transport
AVI51_RS06325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AVI51_RS06350	COG0670	Belongs to the BI1 family
AVI51_RS06355	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AVI51_RS06360	COG2923	Belongs to the DsrF TusC family
AVI51_RS06370	COG2920	part of a sulfur-relay system
AVI51_RS06375	COG2095	MarC family integral membrane protein
AVI51_RS06410	COG0742	ribosomal rna small subunit methyltransferase
AVI51_RS06450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AVI51_RS06455	COG0724	RNA recognition motif
AVI51_RS06460	COG4608	Belongs to the ABC transporter superfamily
AVI51_RS06470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVI51_RS06475	COG0601	transmembrane transport
AVI51_RS06480	COG0747	negative chemotaxis
AVI51_RS06485	COG0527	aspartate kinase activity
AVI51_RS06490	COG0019	diaminopimelate decarboxylase activity
AVI51_RS06505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVI51_RS06505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AVI51_RS06510	COG0463	Glycosyl transferase, family 2
AVI51_RS06515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVI51_RS06520	COG2076	Multidrug Resistance protein
AVI51_RS06525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AVI51_RS06530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVI51_RS06540	COG0745	RESPONSE REGULATOR receiver
AVI51_RS06600	COG0328	RNA-DNA hybrid ribonuclease activity
AVI51_RS06620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVI51_RS06640	COG2963	transposase activity
AVI51_RS06650	COG3335	DDE superfamily endonuclease
AVI51_RS06655	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS06660	COG0601	transmembrane transport
AVI51_RS06690	COG3335	DDE superfamily endonuclease
AVI51_RS06700	COG3335	DDE superfamily endonuclease
AVI51_RS06710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AVI51_RS06715	COG4535	Mg2 and Co2 transporter CorC
AVI51_RS06720	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AVI51_RS06725	COG1702	phosphate starvation-inducible protein PhoH
AVI51_RS06730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVI51_RS06740	COG0617	tRNA 3'-terminal CCA addition
AVI51_RS06765	COG2971	BadF BadG BcrA BcrD
AVI51_RS06770	COG2814	Major facilitator Superfamily
AVI51_RS06775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVI51_RS06780	COG1959	2 iron, 2 sulfur cluster binding
AVI51_RS06790	COG2197	response regulator
AVI51_RS06795	COG2962	Rard protein
AVI51_RS06815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AVI51_RS06820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AVI51_RS06830	COG0628	permease
AVI51_RS06835	COG2076	Multidrug Resistance protein
AVI51_RS06855	COG1619	proteins homologs of microcin C7 resistance protein MccF
AVI51_RS06865	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AVI51_RS06895	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AVI51_RS06900	COG0813	purine-nucleoside phosphorylase activity
AVI51_RS06910	COG0167	dihydroorotate dehydrogenase activity
AVI51_RS06920	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AVI51_RS06920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVI51_RS06940	COG3335	DDE superfamily endonuclease
AVI51_RS06970	COG2217	Heavy metal translocating P-type atpase
AVI51_RS06990	COG0242	peptide deformylase activity
AVI51_RS07000	COG0835	chemotaxis
AVI51_RS07000	COG0784	Response regulator, receiver
AVI51_RS07010	COG0425	Belongs to the sulfur carrier protein TusA family
AVI51_RS07090	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS07100	COG0477	Major facilitator Superfamily
AVI51_RS07115	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS07210	COG2805	Type II/IV secretion system protein
AVI51_RS07255	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AVI51_RS07285	COG0071	Belongs to the small heat shock protein (HSP20) family
AVI51_RS07290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVI51_RS07295	COG0516	GMP reductase activity
AVI51_RS07295	COG0517	IMP dehydrogenase activity
AVI51_RS07310	COG1131	(ABC) transporter
AVI51_RS07320	COG4206	TonB-dependent receptor
AVI51_RS07340	COG0742	ribosomal rna small subunit methyltransferase
AVI51_RS07345	COG1760	l-serine dehydratase
AVI51_RS07375	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AVI51_RS07380	COG3273	potassium ion transport
AVI51_RS07380	COG0471	metal ion transport
AVI51_RS07430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AVI51_RS07470	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AVI51_RS07480	COG0166	Belongs to the GPI family
AVI51_RS07535	COG1063	alcohol dehydrogenase
AVI51_RS07540	COG0156	8-amino-7-oxononanoate synthase activity
AVI51_RS07570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVI51_RS07585	COG0596	Alpha beta hydrolase
AVI51_RS07595	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AVI51_RS07600	COG1040	competence protein
AVI51_RS07615	COG3335	DDE superfamily endonuclease
AVI51_RS07625	COG0783	Belongs to the Dps family
AVI51_RS07640	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AVI51_RS07640	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AVI51_RS07645	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AVI51_RS07660	COG1028	Short-chain dehydrogenase reductase Sdr
AVI51_RS07670	COG0561	phosphatase activity
AVI51_RS07685	COG2801	Transposase and inactivated derivatives
AVI51_RS07710	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AVI51_RS07725	COG3177	Filamentation induced by cAMP protein fic
AVI51_RS07795	COG2801	Transposase and inactivated derivatives
AVI51_RS07805	COG2963	transposase activity
AVI51_RS07820	COG2801	Transposase and inactivated derivatives
AVI51_RS07825	COG2963	transposase activity
AVI51_RS07905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVI51_RS07920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVI51_RS07925	COG0670	Belongs to the BI1 family
AVI51_RS07935	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AVI51_RS07940	COG0739	heme binding
AVI51_RS07965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AVI51_RS07975	COG0009	L-threonylcarbamoyladenylate synthase
AVI51_RS07980	COG2917	probably involved in intracellular septation
AVI51_RS07985	COG2350	Protein conserved in bacteria
AVI51_RS07995	COG3139	Protein of unknown function (DUF1315)
AVI51_RS08000	COG0546	phosphoglycolate phosphatase activity
AVI51_RS08035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVI51_RS08045	COG0205	6-phosphofructokinase activity
AVI51_RS08090	COG3335	DDE superfamily endonuclease
AVI51_RS08105	COG3012	SEC-C Motif Domain Protein
AVI51_RS08120	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AVI51_RS08130	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AVI51_RS08135	COG0235	Class ii aldolase
AVI51_RS08140	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AVI51_RS08145	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AVI51_RS08160	COG0306	phosphate transporter
AVI51_RS08165	COG1392	Phosphate transport regulator
AVI51_RS08215	COG0189	ligase activity
AVI51_RS08225	COG0307	riboflavin synthase, alpha
AVI51_RS08275	COG3293	Transposase
AVI51_RS08280	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AVI51_RS08285	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AVI51_RS08290	COG2814	Major facilitator Superfamily
AVI51_RS08295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AVI51_RS08320	COG0835	chemotaxis
AVI51_RS08320	COG0784	Response regulator, receiver
AVI51_RS08360	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AVI51_RS08370	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS08400	COG3335	DDE superfamily endonuclease
AVI51_RS08415	COG0126	phosphoglycerate kinase activity
AVI51_RS08420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AVI51_RS08425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AVI51_RS08430	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AVI51_RS08440	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AVI51_RS08445	COG0735	belongs to the Fur family
AVI51_RS08460	COG1051	belongs to the nudix hydrolase family
AVI51_RS08495	COG0840	transmembrane signaling receptor activity
AVI51_RS08505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AVI51_RS08515	COG2271	Major facilitator Superfamily
AVI51_RS08530	COG3335	DDE superfamily endonuclease
AVI51_RS08540	COG1047	Peptidyl-prolyl cis-trans
AVI51_RS08545	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AVI51_RS08550	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AVI51_RS08555	COG0196	riboflavin kinase activity
AVI51_RS08560	COG0728	peptidoglycan biosynthetic process
AVI51_RS08580	COG3483	tryptophan 2,3-dioxygenase activity
AVI51_RS08595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVI51_RS08605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVI51_RS08620	COG0776	regulation of translation
AVI51_RS08625	COG0745	RESPONSE REGULATOR receiver
AVI51_RS08640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVI51_RS08645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVI51_RS08650	COG3079	Belongs to the UPF0149 family
AVI51_RS08670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AVI51_RS08690	COG0494	nUDIX hydrolase
AVI51_RS08695	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AVI51_RS08735	COG2801	Transposase and inactivated derivatives
AVI51_RS08760	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AVI51_RS08765	COG0321	lipoyl(octanoyl) transferase activity
AVI51_RS08775	COG1686	Belongs to the peptidase S11 family
AVI51_RS08785	COG2951	lytic endotransglycosylase activity
AVI51_RS08790	COG0772	Belongs to the SEDS family
AVI51_RS08795	COG0768	penicillin binding
AVI51_RS08800	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AVI51_RS08815	COG1466	dna polymerase III delta subunit
AVI51_RS08825	COG0495	leucyl-tRNA aminoacylation
AVI51_RS08835	COG3293	Transposase
AVI51_RS08860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AVI51_RS08870	COG2226	methyltransferase
AVI51_RS08880	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AVI51_RS08895	COG0018	arginyl-trna synthetase
AVI51_RS08900	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AVI51_RS08920	COG3293	Transposase
AVI51_RS08930	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS08935	COG0180	Tryptophanyl-tRNA synthetase
AVI51_RS08940	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AVI51_RS08945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AVI51_RS08975	COG3335	DDE superfamily endonuclease
AVI51_RS08985	COG2801	Transposase and inactivated derivatives
AVI51_RS08995	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AVI51_RS09000	COG2814	Major facilitator Superfamily
AVI51_RS09005	COG0203	ribosomal protein L17
AVI51_RS09010	COG0202	RNA polymerase activity
AVI51_RS09015	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AVI51_RS09020	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AVI51_RS09025	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AVI51_RS09040	COG0200	Binds to the 23S rRNA
AVI51_RS09050	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AVI51_RS09055	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AVI51_RS09060	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AVI51_RS09065	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AVI51_RS09070	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AVI51_RS09080	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AVI51_RS09090	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AVI51_RS09095	COG0255	Belongs to the universal ribosomal protein uL29 family
AVI51_RS09100	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AVI51_RS09105	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AVI51_RS09110	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AVI51_RS09115	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AVI51_RS09120	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AVI51_RS09125	COG0089	rRNA binding
AVI51_RS09130	COG0088	Forms part of the polypeptide exit tunnel
AVI51_RS09135	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AVI51_RS09145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AVI51_RS09150	COG0049	tRNA binding
AVI51_RS09155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AVI51_RS09165	COG0085	RNA polymerase activity
AVI51_RS09170	COG0222	ribosome binding
AVI51_RS09175	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AVI51_RS09180	COG0081	regulation of translation
AVI51_RS09185	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AVI51_RS09195	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVI51_RS09225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVI51_RS09230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVI51_RS09235	COG1459	type II secretion system
AVI51_RS09250	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AVI51_RS09255	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AVI51_RS09265	COG3130	regulation of translation
AVI51_RS09270	COG0477	Major facilitator Superfamily
AVI51_RS09285	COG0484	heat shock protein binding
AVI51_RS09290	COG0443	Heat shock 70 kDa protein
AVI51_RS09295	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AVI51_RS09300	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AVI51_RS09305	COG0497	DNA recombination
AVI51_RS09325	COG0735	belongs to the Fur family
AVI51_RS09340	COG2914	Belongs to the UPF0125 (RnfH) family
AVI51_RS09345	COG2867	negative regulation of translational initiation
AVI51_RS09350	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AVI51_RS09365	COG2066	Belongs to the glutaminase family
AVI51_RS09370	COG0596	Alpha beta hydrolase
AVI51_RS09375	COG1490	D-aminoacyl-tRNA deacylase activity
AVI51_RS09390	COG2853	Lipoprotein
AVI51_RS09415	COG1028	Short-chain dehydrogenase reductase Sdr
AVI51_RS09420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AVI51_RS09445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVI51_RS09450	COG0617	tRNA 3'-terminal CCA addition
AVI51_RS09455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AVI51_RS09465	COG1028	Short-chain dehydrogenase reductase Sdr
AVI51_RS09485	COG3243	poly(R)-hydroxyalkanoic acid synthase
AVI51_RS09495	COG1185	polyribonucleotide nucleotidyltransferase activity
AVI51_RS09500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AVI51_RS09505	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AVI51_RS09510	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AVI51_RS09515	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AVI51_RS09520	COG2251	uridine kinase activity
AVI51_RS09520	COG0195	Participates in both transcription termination and antitermination
AVI51_RS09535	COG1007	ATP synthesis coupled electron transport
AVI51_RS09550	COG0713	ATP synthesis coupled electron transport
AVI51_RS09555	COG0839	Belongs to the complex I subunit 6 family
AVI51_RS09560	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVI51_RS09565	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AVI51_RS09570	COG1034	ATP synthesis coupled electron transport
AVI51_RS09575	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AVI51_RS09580	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AVI51_RS09585	COG0649	NAD binding
AVI51_RS09595	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVI51_RS09600	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVI51_RS09610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVI51_RS09615	COG0149	triose-phosphate isomerase activity
AVI51_RS09635	COG1435	thymidine kinase activity
AVI51_RS09640	COG2363	Small membrane protein
AVI51_RS09655	COG0494	nUDIX hydrolase
AVI51_RS09675	COG1585	Membrane protein implicated in regulation of membrane protease activity
AVI51_RS09680	COG0330	HflC and HflK could
AVI51_RS09685	COG0708	Exodeoxyribonuclease III
AVI51_RS09690	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AVI51_RS09690	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AVI51_RS09695	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AVI51_RS09700	COG3335	DDE superfamily endonuclease
AVI51_RS09715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVI51_RS09720	COG0625	glutathione transferase activity
AVI51_RS09770	COG0281	malic enzyme
AVI51_RS09775	COG0254	rRNA binding
AVI51_RS09780	COG1737	Transcriptional regulator
AVI51_RS09785	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVI51_RS09800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AVI51_RS09805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AVI51_RS09810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AVI51_RS09830	COG1217	gtp-binding protein TYPA
AVI51_RS09845	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AVI51_RS09900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVI51_RS09930	COG0531	amino acid
AVI51_RS09935	COG0174	glutamine synthetase
AVI51_RS09940	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AVI51_RS09945	COG0668	transmembrane transport
AVI51_RS09970	COG2988	succinylglutamate desuccinylase activity
AVI51_RS09985	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS10000	COG2801	Transposase and inactivated derivatives
AVI51_RS10015	COG2271	Major facilitator Superfamily
AVI51_RS10020	COG2814	Major facilitator Superfamily
AVI51_RS10025	COG0583	DNA-binding transcription factor activity
AVI51_RS10035	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AVI51_RS10060	COG3335	DDE superfamily endonuclease
AVI51_RS10110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVI51_RS10120	COG3335	DDE superfamily endonuclease
AVI51_RS10135	COG3335	DDE superfamily endonuclease
AVI51_RS10140	COG0017	Asparaginyl-tRNA synthetase
AVI51_RS10145	COG4962	Type ii secretion system protein e
AVI51_RS10165	COG2948	multi-organism process
AVI51_RS10170	COG3504	Conjugal transfer protein
AVI51_RS10180	COG3451	type IV secretory pathway VirB4
AVI51_RS10195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI51_RS10200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVI51_RS10205	COG0606	chelatase, subunit chli
AVI51_RS10215	COG0347	Belongs to the P(II) protein family
AVI51_RS10220	COG1166	arginine decarboxylase activity
AVI51_RS10235	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AVI51_RS10245	COG0133	tryptophan synthase activity
AVI51_RS10250	COG0135	phosphoribosylanthranilate isomerase activity
AVI51_RS10255	COG0134	indole-3-glycerol-phosphate synthase activity
AVI51_RS10260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVI51_RS10265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVI51_RS10265	COG0512	Glutamine amidotransferase of anthranilate synthase
AVI51_RS10280	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS10290	COG0697	spore germination
AVI51_RS10305	COG3335	DDE superfamily endonuclease
AVI51_RS10340	COG0450	alkyl hydroperoxide reductase
AVI51_RS10400	COG0752	glycyl-tRNA synthetase alpha subunit
AVI51_RS10410	COG1607	acyl-coa hydrolase
AVI51_RS10415	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AVI51_RS10440	COG2828	Protein conserved in bacteria
AVI51_RS10445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AVI51_RS10450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AVI51_RS10455	COG0569	domain protein
AVI51_RS10460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVI51_RS10470	COG0242	peptide deformylase activity
AVI51_RS10475	COG0758	DNA mediated transformation
AVI51_RS10480	COG2922	Belongs to the Smg family
AVI51_RS10490	COG0009	L-threonylcarbamoyladenylate synthase
AVI51_RS10495	COG0408	coproporphyrinogen oxidase activity
AVI51_RS10520	COG2963	transposase activity
AVI51_RS10530	COG4221	oxidoreductase activity
AVI51_RS10540	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS10555	COG2267	carboxylic ester hydrolase activity
AVI51_RS10590	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS10605	COG0109	protoheme IX farnesyltransferase activity
AVI51_RS10610	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AVI51_RS10630	COG2814	Major facilitator Superfamily
AVI51_RS10635	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS10640	COG3676	manually curated
AVI51_RS10645	COG2226	methyltransferase
AVI51_RS10645	COG2867	negative regulation of translational initiation
AVI51_RS10675	COG0489	protein tyrosine kinase activity
AVI51_RS10715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVI51_RS10720	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AVI51_RS10730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AVI51_RS10735	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AVI51_RS10740	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AVI51_RS10745	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVI51_RS10750	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVI51_RS10760	COG0356	it plays a direct role in the translocation of protons across the membrane
AVI51_RS10770	COG1475	DNA binding
AVI51_RS10775	COG1192	Involved in chromosome partitioning
AVI51_RS10790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AVI51_RS10795	COG0706	membrane insertase activity
AVI51_RS10800	COG0594	ribonuclease P activity
AVI51_RS10805	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AVI51_RS10810	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AVI51_RS10815	COG0592	DNA-directed DNA polymerase activity
AVI51_RS10825	COG0187	DNA topoisomerase II activity
AVI51_RS10845	COG2983	Belongs to the UPF0260 family
AVI51_RS10850	COG0275	rRNA processing
AVI51_RS10865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVI51_RS10870	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AVI51_RS10875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AVI51_RS10880	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AVI51_RS10885	COG0772	Belongs to the SEDS family
AVI51_RS10890	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AVI51_RS10895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVI51_RS10905	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AVI51_RS10915	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AVI51_RS10920	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AVI51_RS10925	COG0653	protein targeting
AVI51_RS10955	COG0456	acetyltransferase
AVI51_RS10955	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AVI51_RS10970	COG3227	Zinc metalloprotease (Elastase)
AVI51_RS10980	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVI51_RS10990	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVI51_RS10995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI51_RS10995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI51_RS11015	COG3335	DDE superfamily endonuclease
AVI51_RS11030	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AVI51_RS11040	COG0793	Belongs to the peptidase S41A family
AVI51_RS11050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AVI51_RS11075	COG2963	transposase activity
AVI51_RS11095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVI51_RS11105	COG0189	ligase activity
AVI51_RS11110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVI51_RS11115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AVI51_RS11120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AVI51_RS11135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVI51_RS11155	COG1678	Uncharacterized ACR, COG1678
AVI51_RS11195	COG0814	amino acid
AVI51_RS11200	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AVI51_RS11205	COG0281	malic enzyme
AVI51_RS11215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVI51_RS11245	COG3676	manually curated
AVI51_RS11255	COG4221	oxidoreductase activity
AVI51_RS11290	COG3206	protein involved in exopolysaccharide biosynthesis
AVI51_RS11290	COG0489	protein tyrosine kinase activity
AVI51_RS11295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AVI51_RS11310	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AVI51_RS11320	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AVI51_RS11355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVI51_RS11365	COG2885	chlorophyll binding
AVI51_RS11365	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AVI51_RS11370	COG1278	Cold shock
AVI51_RS11375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVI51_RS11380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVI51_RS11385	COG0745	RESPONSE REGULATOR receiver
AVI51_RS11390	COG5002	protein histidine kinase activity
AVI51_RS11460	COG0583	DNA-binding transcription factor activity
AVI51_RS11470	COG0210	DNA helicase
AVI51_RS11475	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS11485	COG0531	amino acid
AVI51_RS11495	COG0318	PFAM AMP-dependent synthetase and ligase
AVI51_RS11510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVI51_RS11515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI51_RS11580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVI51_RS11585	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AVI51_RS11590	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AVI51_RS11600	COG1054	Belongs to the UPF0176 family
AVI51_RS11615	COG2027	D-alanyl-D-alanine carboxypeptidase
AVI51_RS11620	COG2027	D-alanyl-D-alanine carboxypeptidase
AVI51_RS11635	COG0210	DNA helicase
AVI51_RS11650	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AVI51_RS11660	COG0788	formyltetrahydrofolate deformylase activity
AVI51_RS11690	COG3335	DDE superfamily endonuclease
AVI51_RS11720	COG3335	DDE superfamily endonuclease
AVI51_RS11730	COG0259	pyridoxamine-phosphate oxidase activity
AVI51_RS11750	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AVI51_RS11770	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AVI51_RS11775	COG2119	membrane
AVI51_RS11810	COG1534	Rna-binding protein
AVI51_RS11820	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AVI51_RS11825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVI51_RS11830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVI51_RS11840	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVI51_RS11845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVI51_RS11870	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AVI51_RS11880	COG0511	ligase activity, forming carbon-carbon bonds
AVI51_RS11885	COG0439	Biotin carboxylase
AVI51_RS11900	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AVI51_RS11905	COG0138	bifunctional purine biosynthesis protein purh
AVI51_RS11910	COG0151	Belongs to the GarS family
AVI51_RS11915	COG0006	proline dipeptidase activity
AVI51_RS11925	COG3335	DDE superfamily endonuclease
AVI51_RS11945	COG0835	chemotaxis
AVI51_RS11945	COG0784	Response regulator, receiver
AVI51_RS11950	COG0745	RESPONSE REGULATOR receiver
AVI51_RS11955	COG0531	amino acid
AVI51_RS11975	COG2925	Exonuclease
AVI51_RS11980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AVI51_RS11985	COG2011	ABC-type metal ion transport system permease component
AVI51_RS12005	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AVI51_RS12015	COG0586	Pfam SNARE associated Golgi protein
AVI51_RS12020	COG4536	flavin adenine dinucleotide binding
AVI51_RS12025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AVI51_RS12030	COG2995	paraquat-inducible protein a
AVI51_RS12055	COG1301	dicarboxylic acid transport
AVI51_RS12060	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AVI51_RS12060	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AVI51_RS12065	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AVI51_RS12085	COG3335	DDE superfamily endonuclease
AVI51_RS12100	COG3104	oligopeptide transport
AVI51_RS12105	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AVI51_RS12130	COG2801	Transposase and inactivated derivatives
AVI51_RS12140	COG2801	Transposase and inactivated derivatives
AVI51_RS12145	COG2963	transposase activity
AVI51_RS12150	COG2963	transposase activity
AVI51_RS12160	COG0552	protein localization to endoplasmic reticulum
AVI51_RS12210	COG1183	phosphatidylcholine synthase activity
AVI51_RS12220	COG0456	acetyltransferase
AVI51_RS12230	COG0084	hydrolase, TatD family'
AVI51_RS12240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AVI51_RS12245	COG3335	DDE superfamily endonuclease
AVI51_RS12270	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AVI51_RS12330	COG1981	membrane
AVI51_RS12335	COG0316	Belongs to the HesB IscA family
AVI51_RS12350	COG2963	transposase activity
AVI51_RS12385	COG0084	hydrolase, TatD family'
AVI51_RS12400	COG1028	Short-chain dehydrogenase reductase Sdr
AVI51_RS12405	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AVI51_RS12410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVI51_RS12415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVI51_RS12430	COG3335	DDE superfamily endonuclease
AVI51_RS12445	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AVI51_RS12455	COG0833	amino acid
AVI51_RS12490	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AVI51_RS12500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVI51_RS12505	COG0477	Major facilitator Superfamily
AVI51_RS12620	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AVI51_RS12650	COG2205	protein histidine kinase activity
AVI51_RS12665	COG0500	methyltransferase
AVI51_RS12675	COG0308	aminopeptidase N
AVI51_RS12685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AVI51_RS12690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AVI51_RS12710	COG1113	amino acid transport
AVI51_RS12740	COG0837	glucose binding
AVI51_RS12750	COG3852	Histidine kinase
AVI51_RS12760	COG1677	Flagellar hook-basal body complex protein FliE
AVI51_RS12770	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVI51_RS12805	COG3335	DDE superfamily endonuclease
AVI51_RS12835	COG2009	succinate dehydrogenase
AVI51_RS12840	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AVI51_RS12845	COG1053	succinate dehydrogenase
AVI51_RS12850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AVI51_RS12865	COG0045	succinate-CoA ligase (ADP-forming) activity
AVI51_RS12910	COG1918	ferrous iron import across plasma membrane
AVI51_RS12915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AVI51_RS12925	COG0625	glutathione transferase activity
AVI51_RS12930	COG2969	positive regulation of protein catabolic process
AVI51_RS12935	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AVI51_RS12940	COG0792	nuclease activity
AVI51_RS12950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVI51_RS12955	COG0142	geranyltranstransferase activity
AVI51_RS12960	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AVI51_RS12970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AVI51_RS12985	COG1509	lysine 2,3-aminomutase activity
AVI51_RS12990	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AVI51_RS12995	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AVI51_RS13020	COG0438	transferase activity, transferring glycosyl groups
AVI51_RS13025	COG0436	Aminotransferase
AVI51_RS13030	COG0556	nucleotide-excision repair
AVI51_RS13055	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AVI51_RS13065	COG1086	Polysaccharide biosynthesis protein
AVI51_RS13070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVI51_RS13075	COG1083	cytidylyl-transferase
AVI51_RS13085	COG2089	acid synthase
AVI51_RS13110	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AVI51_RS13120	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AVI51_RS13130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AVI51_RS13135	COG0072	phenylalanine-tRNA ligase activity
AVI51_RS13135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVI51_RS13140	COG0776	regulation of translation
AVI51_RS13150	COG1881	PFAM PEBP family protein
AVI51_RS13160	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS13195	COG0069	glutamate synthase activity
AVI51_RS13210	COG0519	Catalyzes the synthesis of GMP from XMP
AVI51_RS13300	COG3023	N-Acetylmuramoyl-L-alanine amidase
AVI51_RS13360	COG0582	viral genome integration into host DNA
AVI51_RS13415	COG1192	Involved in chromosome partitioning
AVI51_RS13485	COG3335	DDE superfamily endonuclease
AVI51_RS13510	COG0629	single-stranded DNA binding
AVI51_RS13550	COG0114	fumarate hydratase activity
AVI51_RS13555	COG0833	amino acid
AVI51_RS13565	COG2177	Part of the ABC transporter FtsEX involved in
AVI51_RS13570	COG2884	Cell division ATP-binding protein ftsE
AVI51_RS13585	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVI51_RS13590	COG0784	Response regulator, receiver
AVI51_RS13590	COG0835	chemotaxis
AVI51_RS13605	COG3335	DDE superfamily endonuclease
AVI51_RS13620	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS13640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AVI51_RS13650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AVI51_RS13655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AVI51_RS13665	COG2183	response to ionizing radiation
AVI51_RS13690	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AVI51_RS13695	COG2871	sodium ion transport
AVI51_RS13700	COG1438	arginine binding
AVI51_RS13750	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVI51_RS13755	COG0154	amidase activity
AVI51_RS13760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVI51_RS13765	COG1077	Cell shape determining protein MreB Mrl
AVI51_RS13770	COG1792	Involved in formation and maintenance of cell shape
AVI51_RS13780	COG0424	maF-like protein
AVI51_RS13785	COG1530	ribonuclease E activity
AVI51_RS13795	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AVI51_RS13845	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AVI51_RS13850	COG2967	ApaG domain
AVI51_RS13855	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AVI51_RS13860	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AVI51_RS13865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVI51_RS13870	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AVI51_RS13880	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AVI51_RS13890	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AVI51_RS13905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AVI51_RS13910	COG0512	Glutamine amidotransferase of anthranilate synthase
AVI51_RS13915	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AVI51_RS14010	COG0784	Response regulator, receiver
AVI51_RS14010	COG0835	chemotaxis
AVI51_RS14020	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AVI51_RS14035	COG1660	Displays ATPase and GTPase activities
AVI51_RS14050	COG1137	ATPase activity
AVI51_RS14065	COG0517	IMP dehydrogenase activity
AVI51_RS14065	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AVI51_RS14070	COG1127	ABC transporter
AVI51_RS14075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AVI51_RS14080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVI51_RS14095	COG5007	Belongs to the BolA IbaG family
AVI51_RS14115	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AVI51_RS14135	COG3243	poly(R)-hydroxyalkanoic acid synthase
AVI51_RS14140	COG2823	Periplasmic or secreted lipoprotein
AVI51_RS14150	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AVI51_RS14155	COG0416	fatty acid biosynthetic process
AVI51_RS14160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AVI51_RS14165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AVI51_RS14170	COG1028	Short-chain dehydrogenase reductase Sdr
AVI51_RS14175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVI51_RS14180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVI51_RS14185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVI51_RS14190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AVI51_RS14195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AVI51_RS14205	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS14215	COG3293	Transposase
AVI51_RS14240	COG3335	DDE superfamily endonuclease
AVI51_RS14270	COG2827	Endonuclease containing a URI domain
AVI51_RS14275	COG0247	lactate metabolic process
AVI51_RS14275	COG0277	FAD linked oxidase domain protein
AVI51_RS14295	COG3161	chorismate lyase activity
AVI51_RS14300	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AVI51_RS14305	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AVI51_RS14320	COG0859	PFAM glycosyl transferase family 9
AVI51_RS14330	COG1215	transferase activity, transferring glycosyl groups
AVI51_RS14335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVI51_RS14340	COG1519	Transferase
AVI51_RS14345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVI51_RS14350	COG0509	glycine decarboxylation via glycine cleavage system
AVI51_RS14355	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVI51_RS14365	COG3104	oligopeptide transport
AVI51_RS14400	COG2226	methyltransferase
AVI51_RS14415	COG0193	aminoacyl-tRNA hydrolase activity
AVI51_RS14420	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AVI51_RS14425	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AVI51_RS14445	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AVI51_RS14450	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AVI51_RS14455	COG2890	protein-(glutamine-N5) methyltransferase activity
AVI51_RS14460	COG2814	Major facilitator Superfamily
AVI51_RS14480	COG3335	DDE superfamily endonuclease
AVI51_RS14490	COG2171	N-acyltransferase activity
AVI51_RS14495	COG0252	asparaginase activity
AVI51_RS14510	COG0052	Belongs to the universal ribosomal protein uS2 family
AVI51_RS14515	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AVI51_RS14520	COG0528	UMP kinase activity
AVI51_RS14525	COG0233	cytoplasmic translational termination
AVI51_RS14530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AVI51_RS14535	COG0575	Belongs to the CDS family
AVI51_RS14555	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AVI51_RS14570	COG3425	synthase
AVI51_RS14590	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVI51_RS14595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVI51_RS14600	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVI51_RS14610	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AVI51_RS14620	COG0825	malonyl-CoA metabolic process
AVI51_RS14625	COG0037	tRNA processing
AVI51_RS14630	COG0659	secondary active sulfate transmembrane transporter activity
AVI51_RS14665	COG2223	nitrite transmembrane transporter activity
AVI51_RS14670	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS14675	COG3293	Transposase
AVI51_RS14695	COG3335	DDE superfamily endonuclease
AVI51_RS14740	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS14750	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS14785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVI51_RS14785	COG0047	phosphoribosylformylglycinamidine synthase activity
AVI51_RS14815	COG3842	ATPase activity
AVI51_RS14820	COG0351	phosphomethylpyrimidine kinase
AVI51_RS14845	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AVI51_RS14855	COG1566	PFAM secretion protein HlyD family protein
AVI51_RS14860	COG2814	Major facilitator Superfamily
AVI51_RS14865	COG1538	Outer membrane efflux protein
AVI51_RS14870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVI51_RS14885	COG2197	response regulator
AVI51_RS14890	COG0322	excinuclease ABC activity
AVI51_RS14925	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS14945	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS14965	COG0656	L-ascorbic acid biosynthetic process
AVI51_RS14975	COG0477	Major facilitator Superfamily
AVI51_RS14990	COG0626	cystathionine gamma-synthase activity
AVI51_RS15000	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AVI51_RS15015	COG0544	peptidyl-prolyl cis-trans isomerase activity
AVI51_RS15020	COG0740	serine-type endopeptidase activity
AVI51_RS15025	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AVI51_RS15030	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVI51_RS15045	COG1560	Kdo2-lipid A biosynthetic process
AVI51_RS15050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AVI51_RS15060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI51_RS15065	COG2274	protein secretion by the type I secretion system
AVI51_RS15070	COG2274	protein secretion by the type I secretion system
AVI51_RS15075	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AVI51_RS15085	COG1686	Belongs to the peptidase S11 family
AVI51_RS15120	COG0187	DNA topoisomerase II activity
AVI51_RS15140	COG2963	transposase activity
AVI51_RS15145	COG2801	Transposase and inactivated derivatives
AVI51_RS15150	COG0717	Belongs to the dCTP deaminase family
AVI51_RS15165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVI51_RS15170	COG4974	Belongs to the 'phage' integrase family
AVI51_RS15185	COG2801	Transposase and inactivated derivatives
AVI51_RS15210	COG3335	DDE superfamily endonuclease
AVI51_RS15225	COG2801	Transposase and inactivated derivatives
AVI51_RS15245	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS15275	COG3335	DDE superfamily endonuclease
AVI51_RS15325	COG0776	regulation of translation
AVI51_RS15330	COG0494	nUDIX hydrolase
AVI51_RS15335	COG0039	L-malate dehydrogenase activity
AVI51_RS15340	COG1538	Outer membrane efflux protein
AVI51_RS15345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AVI51_RS15350	COG3150	esterase
AVI51_RS15355	COG4988	ABC transporter
AVI51_RS15360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AVI51_RS15380	COG3335	DDE superfamily endonuclease
AVI51_RS15390	COG2826	transposase and inactivated derivatives, IS30 family
AVI51_RS15410	COG3293	Transposase
AVI51_RS15425	COG3104	oligopeptide transport
AVI51_RS15445	COG1058	Belongs to the CinA family
AVI51_RS15445	COG1546	Belongs to the CinA family
AVI51_RS15465	COG4948	Mandelate Racemase Muconate Lactonizing
AVI51_RS15475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVI51_RS15480	COG0450	alkyl hydroperoxide reductase
AVI51_RS15495	COG0500	methyltransferase
AVI51_RS15550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVI51_RS15565	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVI51_RS15570	COG0531	amino acid
AVI51_RS15745	COG0010	Belongs to the arginase family
AVI51_RS16115	COG1530	ribonuclease E activity
AVI51_RS16215	COG1570	exodeoxyribonuclease VII activity
AVI51_RS16220	COG1570	exodeoxyribonuclease VII activity
AVI51_RS16405	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVI51_RS16415	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVI51_RS16425	COG0616	signal peptide processing
AVI51_RS16770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVI51_RS16825	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction