locus-tag	class	description
AVI53_RS00035	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVI53_RS00040	COG1876	peptidase activity
AVI53_RS00045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AVI53_RS00055	COG1090	epimerase
AVI53_RS00075	COG2801	Transposase and inactivated derivatives
AVI53_RS00080	COG3385	transposase activity
AVI53_RS00145	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AVI53_RS00150	COG2894	cell division
AVI53_RS00155	COG0850	regulation of cytokinetic process
AVI53_RS00170	COG0733	neurotransmitter:sodium symporter activity
AVI53_RS00175	COG0708	Exodeoxyribonuclease III
AVI53_RS00205	COG3385	transposase activity
AVI53_RS00240	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVI53_RS00245	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AVI53_RS00250	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVI53_RS00265	COG0326	Molecular chaperone. Has ATPase activity
AVI53_RS00315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI53_RS00315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI53_RS00325	COG0488	(ABC) transporter
AVI53_RS00335	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS00340	COG3385	transposase activity
AVI53_RS00360	COG3385	transposase activity
AVI53_RS00390	COG2801	Transposase and inactivated derivatives
AVI53_RS00405	COG3385	transposase activity
AVI53_RS00415	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS00455	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVI53_RS00455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVI53_RS00470	COG3655	Transcriptional regulator
AVI53_RS00485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AVI53_RS00490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVI53_RS00500	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AVI53_RS00545	COG2805	Type II/IV secretion system protein
AVI53_RS00655	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AVI53_RS00660	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AVI53_RS00665	COG1294	oxidase, subunit
AVI53_RS00675	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AVI53_RS00675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVI53_RS00680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVI53_RS00680	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AVI53_RS00710	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AVI53_RS00725	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AVI53_RS00755	COG0730	response to heat
AVI53_RS00760	COG1671	Belongs to the UPF0178 family
AVI53_RS00765	COG0688	phosphatidylethanolamine metabolic process
AVI53_RS00770	COG1162	GTPase activity
AVI53_RS00780	COG0802	atpase or kinase
AVI53_RS00790	COG0783	Belongs to the Dps family
AVI53_RS00800	COG0753	catalase activity
AVI53_RS00805	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AVI53_RS00810	COG2801	Transposase and inactivated derivatives
AVI53_RS00820	COG3385	transposase activity
AVI53_RS00835	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS00850	COG3385	transposase activity
AVI53_RS00860	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS00870	COG0488	(ABC) transporter
AVI53_RS00880	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AVI53_RS00895	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AVI53_RS00900	COG0285	dihydrofolate synthase activity
AVI53_RS00905	COG1286	toxin biosynthetic process
AVI53_RS00920	COG0405	Gamma-glutamyltransferase
AVI53_RS00935	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AVI53_RS00945	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AVI53_RS00960	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AVI53_RS00995	COG0531	amino acid
AVI53_RS01000	COG0584	glycerophosphoryl diester phosphodiesterase
AVI53_RS01005	COG2271	Major facilitator Superfamily
AVI53_RS01010	COG1923	regulation of RNA biosynthetic process
AVI53_RS01015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AVI53_RS01020	COG0330	HflC and HflK could
AVI53_RS01025	COG0330	HflC and HflK could
AVI53_RS01030	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AVI53_RS01035	COG2252	PERMEase
AVI53_RS01040	COG0557	exoribonuclease II activity
AVI53_RS01045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVI53_RS01060	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS01075	COG2801	Transposase and inactivated derivatives
AVI53_RS01100	COG1120	ATPase activity
AVI53_RS01105	COG0019	diaminopimelate decarboxylase activity
AVI53_RS01115	COG2814	Major facilitator Superfamily
AVI53_RS01125	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVI53_RS01130	COG4772	TonB-dependent receptor
AVI53_RS01135	COG0811	peptide transport
AVI53_RS01155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AVI53_RS01170	COG3385	transposase activity
AVI53_RS01185	COG1902	pentaerythritol trinitrate reductase activity
AVI53_RS01185	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVI53_RS01195	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AVI53_RS01205	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AVI53_RS01210	COG0336	Belongs to the RNA methyltransferase TrmD family
AVI53_RS01215	COG0335	large ribosomal subunit rRNA binding
AVI53_RS01245	COG2801	Transposase and inactivated derivatives
AVI53_RS01265	COG2801	Transposase and inactivated derivatives
AVI53_RS01270	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS01295	COG3385	transposase activity
AVI53_RS01305	COG2801	Transposase and inactivated derivatives
AVI53_RS01345	COG3385	transposase activity
AVI53_RS01360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVI53_RS01365	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AVI53_RS01370	COG0504	CTP synthase activity
AVI53_RS01375	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AVI53_RS01380	COG0148	phosphopyruvate hydratase activity
AVI53_RS01385	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AVI53_RS01390	COG0585	pseudouridine synthase activity
AVI53_RS01395	COG0531	amino acid
AVI53_RS01400	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AVI53_RS01405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVI53_RS01435	COG3385	transposase activity
AVI53_RS01495	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS01500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AVI53_RS01505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVI53_RS01510	COG1845	cytochrome c oxidase, subunit III
AVI53_RS01515	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AVI53_RS01570	COG3104	oligopeptide transport
AVI53_RS01590	COG0814	amino acid
AVI53_RS01600	COG2840	Smr protein MutS2
AVI53_RS01605	COG2890	protein-(glutamine-N5) methyltransferase activity
AVI53_RS01610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AVI53_RS01615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AVI53_RS01660	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AVI53_RS01670	COG0488	(ABC) transporter
AVI53_RS01680	COG0741	lytic transglycosylase activity
AVI53_RS01680	COG1388	LysM domain
AVI53_RS01715	COG1987	bacterial-type flagellum assembly
AVI53_RS01730	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVI53_RS01755	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AVI53_RS01760	COG0643	Histidine kinase
AVI53_RS01760	COG2198	Histidine kinase
AVI53_RS01760	COG0784	Response regulator, receiver
AVI53_RS01780	COG1959	2 iron, 2 sulfur cluster binding
AVI53_RS01785	COG0719	Fe-S assembly protein
AVI53_RS01790	COG0396	ATPase activity
AVI53_RS01795	COG0719	Fe-S assembly protein
AVI53_RS01800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVI53_RS01805	COG0316	Belongs to the HesB IscA family
AVI53_RS01820	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS01830	COG2963	transposase activity
AVI53_RS01845	COG0572	uridine kinase
AVI53_RS01850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AVI53_RS01905	COG0387	Pfam Sodium calcium exchanger
AVI53_RS01910	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS01915	COG0686	Belongs to the AlaDH PNT family
AVI53_RS01930	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS01965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVI53_RS01970	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AVI53_RS01995	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS02015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AVI53_RS02020	COG0477	Major facilitator Superfamily
AVI53_RS02060	COG3385	transposase activity
AVI53_RS02070	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVI53_RS02095	COG2801	Transposase and inactivated derivatives
AVI53_RS02130	COG2801	Transposase and inactivated derivatives
AVI53_RS02155	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS02160	COG3177	Filamentation induced by cAMP protein fic
AVI53_RS02170	COG0475	glutathione-regulated potassium exporter activity
AVI53_RS02170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVI53_RS02190	COG2801	Transposase and inactivated derivatives
AVI53_RS02195	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS02200	COG1115	amino acid carrier protein
AVI53_RS02205	COG0740	serine-type endopeptidase activity
AVI53_RS02215	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AVI53_RS02225	COG1663	tetraacyldisaccharide 4'-kinase activity
AVI53_RS02230	COG1132	(ABC) transporter
AVI53_RS02235	COG0848	biopolymer transport protein
AVI53_RS02240	COG0811	peptide transport
AVI53_RS02255	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS02270	COG2801	Transposase and inactivated derivatives
AVI53_RS02290	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS02295	COG2333	competence protein COMEC
AVI53_RS02295	COG0658	competence protein
AVI53_RS02310	COG0583	DNA-binding transcription factor activity
AVI53_RS02315	COG4991	sh3 domain protein
AVI53_RS02315	COG0515	serine threonine protein kinase
AVI53_RS02315	COG3064	Membrane
AVI53_RS02330	COG0513	Belongs to the DEAD box helicase family
AVI53_RS02335	COG2866	Carboxypeptidase
AVI53_RS02340	COG2095	MarC family integral membrane protein
AVI53_RS02360	COG1280	lysine exporter protein (LysE YggA)
AVI53_RS02375	COG0515	serine threonine protein kinase
AVI53_RS02375	COG2815	serine threonine protein kinase
AVI53_RS02395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AVI53_RS02400	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AVI53_RS02405	COG2814	Major facilitator Superfamily
AVI53_RS02435	COG2801	Transposase and inactivated derivatives
AVI53_RS02450	COG3676	manually curated
AVI53_RS02465	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS02500	COG3064	Membrane
AVI53_RS02500	COG0515	serine threonine protein kinase
AVI53_RS02500	COG4991	sh3 domain protein
AVI53_RS02510	COG0659	secondary active sulfate transmembrane transporter activity
AVI53_RS02515	COG1054	Belongs to the UPF0176 family
AVI53_RS02525	COG0741	lytic transglycosylase activity
AVI53_RS02535	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS02550	COG0513	Belongs to the DEAD box helicase family
AVI53_RS02605	COG0590	tRNA wobble adenosine to inosine editing
AVI53_RS02650	COG2801	Transposase and inactivated derivatives
AVI53_RS02660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVI53_RS02660	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVI53_RS02665	COG3385	transposase activity
AVI53_RS02670	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVI53_RS02670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVI53_RS02685	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS02695	COG1294	oxidase, subunit
AVI53_RS02735	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AVI53_RS02775	COG3385	transposase activity
AVI53_RS02795	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AVI53_RS02805	COG2801	Transposase and inactivated derivatives
AVI53_RS02810	COG2801	Transposase and inactivated derivatives
AVI53_RS02840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVI53_RS02845	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVI53_RS02850	COG0835	chemotaxis
AVI53_RS02850	COG0784	Response regulator, receiver
AVI53_RS02855	COG0596	Alpha beta hydrolase
AVI53_RS02865	COG1643	Atp-dependent helicase
AVI53_RS02880	COG2070	2-Nitropropane dioxygenase
AVI53_RS02885	COG3321	synthase
AVI53_RS02885	COG1028	Short-chain dehydrogenase reductase Sdr
AVI53_RS02885	COG0604	alcohol dehydrogenase
AVI53_RS02900	COG1028	Short-chain dehydrogenase reductase Sdr
AVI53_RS02900	COG3321	synthase
AVI53_RS02900	COG0604	alcohol dehydrogenase
AVI53_RS02920	COG2963	transposase activity
AVI53_RS02925	COG0835	chemotaxis
AVI53_RS02925	COG0784	Response regulator, receiver
AVI53_RS02945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVI53_RS02945	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AVI53_RS02980	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AVI53_RS02980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVI53_RS03005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVI53_RS03010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI53_RS03015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVI53_RS03025	COG0729	surface antigen
AVI53_RS03040	COG1376	ErfK ybiS ycfS ynhG family protein
AVI53_RS03175	COG2801	Transposase and inactivated derivatives
AVI53_RS03190	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS03200	COG3385	transposase activity
AVI53_RS03225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVI53_RS03230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI53_RS03235	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AVI53_RS03250	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS03270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AVI53_RS03285	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AVI53_RS03290	COG2081	HI0933 family
AVI53_RS03295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVI53_RS03305	COG1024	Enoyl-CoA hydratase
AVI53_RS03315	COG3501	Rhs element vgr protein
AVI53_RS03330	COG1960	acyl-CoA dehydrogenase activity
AVI53_RS03335	COG0183	Belongs to the thiolase family
AVI53_RS03340	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVI53_RS03340	COG1024	Enoyl-CoA hydratase
AVI53_RS03365	COG2963	transposase activity
AVI53_RS03400	COG2957	Belongs to the agmatine deiminase family
AVI53_RS03405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVI53_RS03415	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AVI53_RS03450	COG0717	Belongs to the dCTP deaminase family
AVI53_RS03460	COG1968	undecaprenyl-diphosphatase activity
AVI53_RS03480	COG3385	transposase activity
AVI53_RS03515	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS03545	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS03555	COG0564	pseudouridine synthase activity
AVI53_RS03610	COG4221	oxidoreductase activity
AVI53_RS03620	COG4221	oxidoreductase activity
AVI53_RS03655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVI53_RS03670	COG2801	Transposase and inactivated derivatives
AVI53_RS03690	COG3385	transposase activity
AVI53_RS03730	COG0531	amino acid
AVI53_RS03770	COG3385	transposase activity
AVI53_RS03795	COG1256	bacterial-type flagellum assembly
AVI53_RS03795	COG4786	Flagellar basal body rod
AVI53_RS03805	COG1706	bacterial-type flagellum-dependent cell motility
AVI53_RS03815	COG4786	Flagellar basal body rod
AVI53_RS03820	COG4787	bacterial-type flagellum-dependent cell motility
AVI53_RS03825	COG1749	Flagellar hook protein flgE
AVI53_RS03830	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AVI53_RS03860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AVI53_RS03865	COG0482	sulfurtransferase activity
AVI53_RS03875	COG3385	transposase activity
AVI53_RS03885	COG2022	thiamine diphosphate biosynthetic process
AVI53_RS03900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVI53_RS03905	COG0531	amino acid
AVI53_RS03930	COG2801	Transposase and inactivated derivatives
AVI53_RS03965	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS03980	COG1393	Belongs to the ArsC family
AVI53_RS03985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVI53_RS03990	COG2066	Belongs to the glutaminase family
AVI53_RS03995	COG0736	holo-[acyl-carrier-protein] synthase activity
AVI53_RS04005	COG1381	Involved in DNA repair and RecF pathway recombination
AVI53_RS04025	COG0681	Belongs to the peptidase S26 family
AVI53_RS04035	COG1595	DNA-templated transcription, initiation
AVI53_RS04050	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AVI53_RS04085	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS04090	COG2801	Transposase and inactivated derivatives
AVI53_RS04125	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS04135	COG0583	DNA-binding transcription factor activity
AVI53_RS04140	COG1199	ATP-dependent helicase activity
AVI53_RS04170	COG4520	surface antigen
AVI53_RS04190	COG0305	Participates in initiation and elongation during chromosome replication
AVI53_RS04195	COG0359	binds to the 23S rRNA
AVI53_RS04200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AVI53_RS04205	COG0360	Binds together with S18 to 16S ribosomal RNA
AVI53_RS04220	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AVI53_RS04225	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AVI53_RS04230	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AVI53_RS04235	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AVI53_RS04245	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AVI53_RS04270	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS04275	COG2801	Transposase and inactivated derivatives
AVI53_RS04310	COG3385	transposase activity
AVI53_RS04325	COG1074	ATP-dependent DNA helicase activity
AVI53_RS04335	COG2814	Major facilitator Superfamily
AVI53_RS04355	COG3385	transposase activity
AVI53_RS04385	COG2801	Transposase and inactivated derivatives
AVI53_RS04420	COG1360	Flagellar Motor Protein
AVI53_RS04425	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AVI53_RS04430	COG0142	geranyltranstransferase activity
AVI53_RS04435	COG1469	GTP cyclohydrolase I activity
AVI53_RS04470	COG2801	Transposase and inactivated derivatives
AVI53_RS04485	COG3385	transposase activity
AVI53_RS04500	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS04505	COG2963	transposase activity
AVI53_RS04520	COG2801	Transposase and inactivated derivatives
AVI53_RS04535	COG2801	Transposase and inactivated derivatives
AVI53_RS04585	COG1366	Belongs to the anti-sigma-factor antagonist family
AVI53_RS04600	COG2304	oxidoreductase activity
AVI53_RS04605	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS04625	COG0714	Associated with various cellular activities
AVI53_RS04630	COG0604	alcohol dehydrogenase
AVI53_RS04670	COG0840	transmembrane signaling receptor activity
AVI53_RS04700	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS04730	COG3385	transposase activity
AVI53_RS04735	COG2801	Transposase and inactivated derivatives
AVI53_RS04810	COG0189	ligase activity
AVI53_RS04815	COG1131	(ABC) transporter
AVI53_RS04870	COG0835	chemotaxis
AVI53_RS04870	COG0784	Response regulator, receiver
AVI53_RS04885	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS04890	COG3385	transposase activity
AVI53_RS04910	COG2860	membrane
AVI53_RS04920	COG2166	iron-sulfur cluster assembly
AVI53_RS04935	COG2801	Transposase and inactivated derivatives
AVI53_RS04965	COG2205	protein histidine kinase activity
AVI53_RS04970	COG0745	RESPONSE REGULATOR receiver
AVI53_RS04990	COG0424	maF-like protein
AVI53_RS05005	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AVI53_RS05010	COG2902	Dehydrogenase
AVI53_RS05020	COG2766	serine protein kinase
AVI53_RS05030	COG2719	SpoVR family
AVI53_RS05040	COG1994	Peptidase M50
AVI53_RS05055	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AVI53_RS05070	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVI53_RS05070	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVI53_RS05080	COG1940	carbohydrate kinase activity
AVI53_RS05085	COG1011	Hydrolase
AVI53_RS05095	COG4178	(ABC) transporter
AVI53_RS05105	COG1194	a g-specific adenine glycosylase
AVI53_RS05110	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AVI53_RS05125	COG2801	Transposase and inactivated derivatives
AVI53_RS05175	COG3724	N-succinylarginine dihydrolase activity
AVI53_RS05180	COG1012	belongs to the aldehyde dehydrogenase family
AVI53_RS05190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AVI53_RS05195	COG1607	acyl-coa hydrolase
AVI53_RS05200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AVI53_RS05205	COG1561	YicC-like family, N-terminal region
AVI53_RS05210	COG0194	GDP metabolic process
AVI53_RS05215	COG1758	RNA polymerase activity
AVI53_RS05220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVI53_RS05245	COG0477	Major facilitator Superfamily
AVI53_RS05250	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS05255	COG3385	transposase activity
AVI53_RS05270	COG3385	transposase activity
AVI53_RS05285	COG0477	Major facilitator Superfamily
AVI53_RS05320	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AVI53_RS05330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVI53_RS05345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVI53_RS05345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVI53_RS05350	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AVI53_RS05355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AVI53_RS05360	COG0488	(ABC) transporter
AVI53_RS05400	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS05410	COG0346	lactoylglutathione lyase activity
AVI53_RS05415	COG1555	photosystem II stabilization
AVI53_RS05430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AVI53_RS05435	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AVI53_RS05450	COG3676	manually curated
AVI53_RS05455	COG0402	S-adenosylhomocysteine deaminase activity
AVI53_RS05480	COG0798	PFAM Bile acid sodium symporter
AVI53_RS05485	COG3385	transposase activity
AVI53_RS05510	COG0505	Belongs to the CarA family
AVI53_RS05515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AVI53_RS05520	COG0540	Belongs to the ATCase OTCase family
AVI53_RS05525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AVI53_RS05535	COG0542	response to heat
AVI53_RS05540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVI53_RS05570	COG2814	Major facilitator Superfamily
AVI53_RS05575	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVI53_RS05575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVI53_RS05580	COG2878	Part of a membrane complex involved in electron transport
AVI53_RS05585	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AVI53_RS05635	COG0670	Belongs to the BI1 family
AVI53_RS05640	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AVI53_RS05655	COG2920	part of a sulfur-relay system
AVI53_RS05660	COG2095	MarC family integral membrane protein
AVI53_RS05695	COG0742	ribosomal rna small subunit methyltransferase
AVI53_RS05745	COG2971	BadF BadG BcrA BcrD
AVI53_RS05750	COG2814	Major facilitator Superfamily
AVI53_RS05755	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVI53_RS05760	COG1959	2 iron, 2 sulfur cluster binding
AVI53_RS05765	COG1017	nitric oxide dioxygenase activity
AVI53_RS05765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AVI53_RS05770	COG2197	response regulator
AVI53_RS05780	COG2962	Rard protein
AVI53_RS05800	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AVI53_RS05805	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AVI53_RS05815	COG0628	permease
AVI53_RS05820	COG2076	Multidrug Resistance protein
AVI53_RS05840	COG1619	proteins homologs of microcin C7 resistance protein MccF
AVI53_RS05850	COG3385	transposase activity
AVI53_RS05860	COG2963	transposase activity
AVI53_RS05895	COG3385	transposase activity
AVI53_RS05930	COG2814	Major facilitator Superfamily
AVI53_RS05935	COG2890	protein-(glutamine-N5) methyltransferase activity
AVI53_RS05940	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AVI53_RS05945	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AVI53_RS05965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AVI53_RS05970	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AVI53_RS05975	COG0193	aminoacyl-tRNA hydrolase activity
AVI53_RS05985	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVI53_RS05990	COG2226	methyltransferase
AVI53_RS06010	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS06030	COG3385	transposase activity
AVI53_RS06050	COG3104	oligopeptide transport
AVI53_RS06060	COG2801	Transposase and inactivated derivatives
AVI53_RS06065	COG3104	oligopeptide transport
AVI53_RS06080	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVI53_RS06085	COG0509	glycine decarboxylation via glycine cleavage system
AVI53_RS06090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVI53_RS06095	COG1519	Transferase
AVI53_RS06100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVI53_RS06105	COG1215	transferase activity, transferring glycosyl groups
AVI53_RS06115	COG0859	PFAM glycosyl transferase family 9
AVI53_RS06130	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AVI53_RS06135	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AVI53_RS06140	COG3161	chorismate lyase activity
AVI53_RS06160	COG0247	lactate metabolic process
AVI53_RS06160	COG0277	FAD linked oxidase domain protein
AVI53_RS06165	COG2827	Endonuclease containing a URI domain
AVI53_RS06195	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS06225	COG3385	transposase activity
AVI53_RS06235	COG2801	Transposase and inactivated derivatives
AVI53_RS06240	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS06255	COG2963	transposase activity
AVI53_RS06260	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AVI53_RS06265	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AVI53_RS06270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVI53_RS06275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVI53_RS06280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVI53_RS06285	COG1028	Short-chain dehydrogenase reductase Sdr
AVI53_RS06290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AVI53_RS06295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AVI53_RS06300	COG0416	fatty acid biosynthetic process
AVI53_RS06305	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AVI53_RS06315	COG2823	Periplasmic or secreted lipoprotein
AVI53_RS06320	COG3243	poly(R)-hydroxyalkanoic acid synthase
AVI53_RS06345	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AVI53_RS06380	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVI53_RS06385	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AVI53_RS06390	COG1127	ABC transporter
AVI53_RS06395	COG0517	IMP dehydrogenase activity
AVI53_RS06395	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AVI53_RS06410	COG1137	ATPase activity
AVI53_RS06425	COG1660	Displays ATPase and GTPase activities
AVI53_RS06440	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AVI53_RS06450	COG0835	chemotaxis
AVI53_RS06450	COG0784	Response regulator, receiver
AVI53_RS06540	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AVI53_RS06545	COG0512	Glutamine amidotransferase of anthranilate synthase
AVI53_RS06550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AVI53_RS06565	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AVI53_RS06585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVI53_RS06590	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AVI53_RS06595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AVI53_RS06600	COG2967	ApaG domain
AVI53_RS06605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AVI53_RS06615	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS06625	COG3385	transposase activity
AVI53_RS06640	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AVI53_RS06645	COG4535	Mg2 and Co2 transporter CorC
AVI53_RS06655	COG1702	phosphate starvation-inducible protein PhoH
AVI53_RS06660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVI53_RS06665	COG0617	tRNA 3'-terminal CCA addition
AVI53_RS06670	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS06705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AVI53_RS06710	COG0724	RNA recognition motif
AVI53_RS06715	COG4608	Belongs to the ABC transporter superfamily
AVI53_RS06725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVI53_RS06730	COG0601	transmembrane transport
AVI53_RS06735	COG0747	negative chemotaxis
AVI53_RS06740	COG0527	aspartate kinase activity
AVI53_RS06745	COG0019	diaminopimelate decarboxylase activity
AVI53_RS06765	COG0463	Glycosyl transferase, family 2
AVI53_RS06770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVI53_RS06775	COG2076	Multidrug Resistance protein
AVI53_RS06780	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AVI53_RS06785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVI53_RS06795	COG0745	RESPONSE REGULATOR receiver
AVI53_RS06850	COG3385	transposase activity
AVI53_RS06855	COG0601	transmembrane transport
AVI53_RS06860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVI53_RS06880	COG0328	RNA-DNA hybrid ribonuclease activity
AVI53_RS06905	COG3385	transposase activity
AVI53_RS06915	COG4166	transmembrane transport
AVI53_RS06950	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AVI53_RS06955	COG0813	purine-nucleoside phosphorylase activity
AVI53_RS06965	COG0167	dihydroorotate dehydrogenase activity
AVI53_RS06975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVI53_RS06975	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AVI53_RS07005	COG2217	Heavy metal translocating P-type atpase
AVI53_RS07010	COG2217	Heavy metal translocating P-type atpase
AVI53_RS07015	COG2217	Heavy metal translocating P-type atpase
AVI53_RS07050	COG0835	chemotaxis
AVI53_RS07050	COG0784	Response regulator, receiver
AVI53_RS07060	COG0425	Belongs to the sulfur carrier protein TusA family
AVI53_RS07135	COG0477	Major facilitator Superfamily
AVI53_RS07160	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS07255	COG2805	Type II/IV secretion system protein
AVI53_RS07310	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AVI53_RS07330	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS07340	COG3385	transposase activity
AVI53_RS07350	COG0071	Belongs to the small heat shock protein (HSP20) family
AVI53_RS07355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVI53_RS07370	COG3385	transposase activity
AVI53_RS07380	COG1131	(ABC) transporter
AVI53_RS07390	COG4206	TonB-dependent receptor
AVI53_RS07410	COG1280	lysine exporter protein (LysE YggA)
AVI53_RS07415	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AVI53_RS07425	COG3385	transposase activity
AVI53_RS07440	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS07450	COG3385	transposase activity
AVI53_RS07460	COG3012	SEC-C Motif Domain Protein
AVI53_RS07470	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AVI53_RS07475	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AVI53_RS07490	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AVI53_RS07495	COG0235	Class ii aldolase
AVI53_RS07500	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AVI53_RS07520	COG0306	phosphate transporter
AVI53_RS07525	COG1392	Phosphate transport regulator
AVI53_RS07560	COG3385	transposase activity
AVI53_RS07565	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS07585	COG0833	amino acid
AVI53_RS07610	COG3385	transposase activity
AVI53_RS07615	COG3385	transposase activity
AVI53_RS07645	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS07650	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS07665	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS07670	COG0724	RNA recognition motif
AVI53_RS07675	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS07775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVI53_RS07830	COG0586	Pfam SNARE associated Golgi protein
AVI53_RS07835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVI53_RS07850	COG3385	transposase activity
AVI53_RS07860	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS07865	COG1063	alcohol dehydrogenase
AVI53_RS07870	COG0156	8-amino-7-oxononanoate synthase activity
AVI53_RS07910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVI53_RS07925	COG0596	Alpha beta hydrolase
AVI53_RS07940	COG1040	competence protein
AVI53_RS07965	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AVI53_RS07965	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AVI53_RS07970	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AVI53_RS07985	COG1028	Short-chain dehydrogenase reductase Sdr
AVI53_RS08010	COG0561	phosphatase activity
AVI53_RS08020	COG3385	transposase activity
AVI53_RS08045	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVI53_RS08055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVI53_RS08070	COG0776	regulation of translation
AVI53_RS08075	COG0745	RESPONSE REGULATOR receiver
AVI53_RS08090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVI53_RS08095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVI53_RS08100	COG3079	Belongs to the UPF0149 family
AVI53_RS08120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AVI53_RS08140	COG0494	nUDIX hydrolase
AVI53_RS08145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AVI53_RS08165	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS08195	COG3385	transposase activity
AVI53_RS08205	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AVI53_RS08210	COG0321	lipoyl(octanoyl) transferase activity
AVI53_RS08220	COG1686	Belongs to the peptidase S11 family
AVI53_RS08230	COG2951	lytic endotransglycosylase activity
AVI53_RS08235	COG0772	Belongs to the SEDS family
AVI53_RS08240	COG0768	penicillin binding
AVI53_RS08245	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AVI53_RS08255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AVI53_RS08260	COG1466	dna polymerase III delta subunit
AVI53_RS08270	COG0495	leucyl-tRNA aminoacylation
AVI53_RS08295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AVI53_RS08315	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AVI53_RS08330	COG0018	arginyl-trna synthetase
AVI53_RS08335	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AVI53_RS08355	COG0180	Tryptophanyl-tRNA synthetase
AVI53_RS08360	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AVI53_RS08365	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AVI53_RS08370	COG1253	flavin adenine dinucleotide binding
AVI53_RS08385	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS08390	COG2801	Transposase and inactivated derivatives
AVI53_RS08395	COG3385	transposase activity
AVI53_RS08420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AVI53_RS08425	COG2814	Major facilitator Superfamily
AVI53_RS08430	COG0203	ribosomal protein L17
AVI53_RS08435	COG0202	RNA polymerase activity
AVI53_RS08440	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AVI53_RS08445	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AVI53_RS08450	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AVI53_RS08465	COG0200	Binds to the 23S rRNA
AVI53_RS08475	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AVI53_RS08480	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AVI53_RS08485	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AVI53_RS08490	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AVI53_RS08495	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AVI53_RS08505	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AVI53_RS08515	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AVI53_RS08520	COG0255	Belongs to the universal ribosomal protein uL29 family
AVI53_RS08525	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AVI53_RS08530	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AVI53_RS08535	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AVI53_RS08540	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AVI53_RS08545	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AVI53_RS08550	COG0089	rRNA binding
AVI53_RS08555	COG0088	Forms part of the polypeptide exit tunnel
AVI53_RS08560	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AVI53_RS08570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AVI53_RS08575	COG0049	tRNA binding
AVI53_RS08580	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AVI53_RS08590	COG0085	RNA polymerase activity
AVI53_RS08595	COG0222	ribosome binding
AVI53_RS08600	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AVI53_RS08605	COG0081	regulation of translation
AVI53_RS08610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AVI53_RS08620	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVI53_RS08655	COG1459	type II secretion system
AVI53_RS08675	COG0237	dephospho-CoA kinase activity
AVI53_RS08680	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AVI53_RS08685	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AVI53_RS08695	COG3130	regulation of translation
AVI53_RS08700	COG0477	Major facilitator Superfamily
AVI53_RS08710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AVI53_RS08715	COG0484	heat shock protein binding
AVI53_RS08720	COG0443	Heat shock 70 kDa protein
AVI53_RS08725	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AVI53_RS08730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AVI53_RS08735	COG0497	DNA recombination
AVI53_RS08745	COG0735	belongs to the Fur family
AVI53_RS08760	COG2914	Belongs to the UPF0125 (RnfH) family
AVI53_RS08765	COG2867	negative regulation of translational initiation
AVI53_RS08770	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AVI53_RS08775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AVI53_RS08785	COG2066	Belongs to the glutaminase family
AVI53_RS08795	COG1490	D-aminoacyl-tRNA deacylase activity
AVI53_RS08810	COG2853	Lipoprotein
AVI53_RS08820	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
AVI53_RS08845	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS08850	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AVI53_RS08880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVI53_RS08885	COG0617	tRNA 3'-terminal CCA addition
AVI53_RS08890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AVI53_RS08900	COG1028	Short-chain dehydrogenase reductase Sdr
AVI53_RS08920	COG3243	poly(R)-hydroxyalkanoic acid synthase
AVI53_RS08930	COG1185	polyribonucleotide nucleotidyltransferase activity
AVI53_RS08935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AVI53_RS08940	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AVI53_RS08945	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AVI53_RS08950	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AVI53_RS08955	COG0195	Participates in both transcription termination and antitermination
AVI53_RS08955	COG2251	uridine kinase activity
AVI53_RS08970	COG1007	ATP synthesis coupled electron transport
AVI53_RS08985	COG0713	ATP synthesis coupled electron transport
AVI53_RS08990	COG0839	Belongs to the complex I subunit 6 family
AVI53_RS08995	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVI53_RS09000	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AVI53_RS09005	COG1034	ATP synthesis coupled electron transport
AVI53_RS09005	COG1034	ATP synthesis coupled electron transport
AVI53_RS09010	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AVI53_RS09015	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AVI53_RS09020	COG0649	NAD binding
AVI53_RS09030	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVI53_RS09035	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVI53_RS09045	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVI53_RS09050	COG0149	triose-phosphate isomerase activity
AVI53_RS09070	COG1435	thymidine kinase activity
AVI53_RS09085	COG2363	Small membrane protein
AVI53_RS09100	COG0494	nUDIX hydrolase
AVI53_RS09120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVI53_RS09130	COG0254	rRNA binding
AVI53_RS09135	COG0281	malic enzyme
AVI53_RS09150	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS09165	COG3186	Phenylalanine-4-hydroxylase
AVI53_RS09180	COG0625	glutathione transferase activity
AVI53_RS09185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVI53_RS09200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AVI53_RS09200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AVI53_RS09205	COG0708	Exodeoxyribonuclease III
AVI53_RS09210	COG0330	HflC and HflK could
AVI53_RS09215	COG1585	Membrane protein implicated in regulation of membrane protease activity
AVI53_RS09240	COG3385	transposase activity
AVI53_RS09260	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AVI53_RS09265	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AVI53_RS09270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AVI53_RS09290	COG1217	gtp-binding protein TYPA
AVI53_RS09315	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS09325	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AVI53_RS09380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVI53_RS09400	COG0248	Ppx GppA phosphatase
AVI53_RS09415	COG0531	amino acid
AVI53_RS09420	COG0174	glutamine synthetase
AVI53_RS09430	COG0668	transmembrane transport
AVI53_RS09460	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AVI53_RS09470	COG2988	succinylglutamate desuccinylase activity
AVI53_RS09495	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS09500	COG2271	Major facilitator Superfamily
AVI53_RS09505	COG2814	Major facilitator Superfamily
AVI53_RS09510	COG0583	DNA-binding transcription factor activity
AVI53_RS09520	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AVI53_RS09525	COG4796	Type ii and iii secretion system protein
AVI53_RS09575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVI53_RS09580	COG0017	Asparaginyl-tRNA synthetase
AVI53_RS09585	COG4962	Type ii secretion system protein e
AVI53_RS09610	COG3504	Conjugal transfer protein
AVI53_RS09620	COG3451	type IV secretory pathway VirB4
AVI53_RS09650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVI53_RS09655	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS09670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVI53_RS09675	COG0606	chelatase, subunit chli
AVI53_RS09685	COG0347	Belongs to the P(II) protein family
AVI53_RS09690	COG1166	arginine decarboxylase activity
AVI53_RS09700	COG0463	Glycosyl transferase, family 2
AVI53_RS09705	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AVI53_RS09715	COG0133	tryptophan synthase activity
AVI53_RS09725	COG0134	indole-3-glycerol-phosphate synthase activity
AVI53_RS09730	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVI53_RS09735	COG0512	Glutamine amidotransferase of anthranilate synthase
AVI53_RS09735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVI53_RS09770	COG0450	alkyl hydroperoxide reductase
AVI53_RS09795	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS09800	COG3385	transposase activity
AVI53_RS09805	COG3385	transposase activity
AVI53_RS09845	COG0752	glycyl-tRNA synthetase alpha subunit
AVI53_RS09855	COG1607	acyl-coa hydrolase
AVI53_RS09860	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AVI53_RS09885	COG2828	Protein conserved in bacteria
AVI53_RS09890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AVI53_RS09895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AVI53_RS09900	COG0569	domain protein
AVI53_RS09905	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVI53_RS09910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AVI53_RS09915	COG0242	peptide deformylase activity
AVI53_RS09920	COG0758	DNA mediated transformation
AVI53_RS09925	COG2922	Belongs to the Smg family
AVI53_RS09935	COG0009	L-threonylcarbamoyladenylate synthase
AVI53_RS09940	COG0408	coproporphyrinogen oxidase activity
AVI53_RS09950	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS09970	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS09985	COG3385	transposase activity
AVI53_RS10010	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AVI53_RS10020	COG0793	Belongs to the peptidase S41A family
AVI53_RS10030	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AVI53_RS10040	COG3385	transposase activity
AVI53_RS10065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI53_RS10065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI53_RS10070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVI53_RS10080	COG3227	Zinc metalloprotease (Elastase)
AVI53_RS10095	COG0456	acetyltransferase
AVI53_RS10095	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AVI53_RS10135	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AVI53_RS10140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AVI53_RS10150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AVI53_RS10155	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVI53_RS10160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVI53_RS10165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AVI53_RS10170	COG0772	Belongs to the SEDS family
AVI53_RS10175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AVI53_RS10185	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AVI53_RS10190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVI53_RS10205	COG0275	rRNA processing
AVI53_RS10210	COG2983	Belongs to the UPF0260 family
AVI53_RS10230	COG0187	DNA topoisomerase II activity
AVI53_RS10245	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AVI53_RS10250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AVI53_RS10255	COG0594	ribonuclease P activity
AVI53_RS10260	COG0706	membrane insertase activity
AVI53_RS10265	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AVI53_RS10280	COG1192	Involved in chromosome partitioning
AVI53_RS10285	COG1475	DNA binding
AVI53_RS10295	COG0356	it plays a direct role in the translocation of protons across the membrane
AVI53_RS10305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVI53_RS10310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVI53_RS10315	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AVI53_RS10320	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AVI53_RS10325	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AVI53_RS10335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AVI53_RS10340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVI53_RS10365	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS10395	COG0489	protein tyrosine kinase activity
AVI53_RS10420	COG3385	transposase activity
AVI53_RS10430	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS10440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AVI53_RS10440	COG0517	IMP dehydrogenase activity
AVI53_RS10450	COG2867	negative regulation of translational initiation
AVI53_RS10450	COG2226	methyltransferase
AVI53_RS10465	COG2814	Major facilitator Superfamily
AVI53_RS10485	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AVI53_RS10490	COG0109	protoheme IX farnesyltransferase activity
AVI53_RS10500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVI53_RS10525	COG3385	transposase activity
AVI53_RS10560	COG3385	transposase activity
AVI53_RS10605	COG4221	oxidoreductase activity
AVI53_RS10625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVI53_RS10635	COG0189	ligase activity
AVI53_RS10640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVI53_RS10645	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AVI53_RS10665	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVI53_RS10685	COG1678	Uncharacterized ACR, COG1678
AVI53_RS10690	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AVI53_RS10715	COG0814	amino acid
AVI53_RS10720	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AVI53_RS10725	COG0281	malic enzyme
AVI53_RS10735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVI53_RS10745	COG4221	oxidoreductase activity
AVI53_RS10780	COG3206	protein involved in exopolysaccharide biosynthesis
AVI53_RS10780	COG0489	protein tyrosine kinase activity
AVI53_RS10785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AVI53_RS10800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AVI53_RS10810	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AVI53_RS10815	COG1215	transferase activity, transferring glycosyl groups
AVI53_RS10825	COG0297	glycogen (starch) synthase activity
AVI53_RS10830	COG0438	transferase activity, transferring glycosyl groups
AVI53_RS10845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVI53_RS10855	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AVI53_RS10855	COG2885	chlorophyll binding
AVI53_RS10860	COG1278	Cold shock
AVI53_RS10865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVI53_RS10870	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS10875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVI53_RS10880	COG0745	RESPONSE REGULATOR receiver
AVI53_RS10900	COG0181	hydroxymethylbilane synthase activity
AVI53_RS10955	COG0583	DNA-binding transcription factor activity
AVI53_RS10970	COG0210	DNA helicase
AVI53_RS10980	COG0531	amino acid
AVI53_RS10990	COG0318	PFAM AMP-dependent synthetase and ligase
AVI53_RS11010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVI53_RS11015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI53_RS11070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVI53_RS11075	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AVI53_RS11080	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AVI53_RS11090	COG1054	Belongs to the UPF0176 family
AVI53_RS11105	COG2027	D-alanyl-D-alanine carboxypeptidase
AVI53_RS11110	COG2027	D-alanyl-D-alanine carboxypeptidase
AVI53_RS11125	COG0210	DNA helicase
AVI53_RS11140	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AVI53_RS11150	COG0788	formyltetrahydrofolate deformylase activity
AVI53_RS11180	COG0259	pyridoxamine-phosphate oxidase activity
AVI53_RS11210	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AVI53_RS11230	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AVI53_RS11235	COG2119	membrane
AVI53_RS11250	COG3385	transposase activity
AVI53_RS11280	COG1534	Rna-binding protein
AVI53_RS11290	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AVI53_RS11295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVI53_RS11300	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVI53_RS11310	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVI53_RS11315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVI53_RS11340	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AVI53_RS11345	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AVI53_RS11350	COG0511	ligase activity, forming carbon-carbon bonds
AVI53_RS11355	COG0439	Biotin carboxylase
AVI53_RS11370	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AVI53_RS11375	COG0138	bifunctional purine biosynthesis protein purh
AVI53_RS11380	COG0151	Belongs to the GarS family
AVI53_RS11385	COG0006	proline dipeptidase activity
AVI53_RS11400	COG0745	RESPONSE REGULATOR receiver
AVI53_RS11405	COG0531	amino acid
AVI53_RS11425	COG2925	Exonuclease
AVI53_RS11435	COG2011	ABC-type metal ion transport system permease component
AVI53_RS11455	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AVI53_RS11460	COG2070	2-Nitropropane dioxygenase
AVI53_RS11465	COG0586	Pfam SNARE associated Golgi protein
AVI53_RS11470	COG4536	flavin adenine dinucleotide binding
AVI53_RS11475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AVI53_RS11480	COG2995	paraquat-inducible protein a
AVI53_RS11505	COG1301	dicarboxylic acid transport
AVI53_RS11515	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AVI53_RS11535	COG3385	transposase activity
AVI53_RS11540	COG3104	oligopeptide transport
AVI53_RS11545	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AVI53_RS11555	COG2801	Transposase and inactivated derivatives
AVI53_RS11570	COG0552	protein localization to endoplasmic reticulum
AVI53_RS11585	COG3385	transposase activity
AVI53_RS11605	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS11620	COG3385	transposase activity
AVI53_RS11665	COG1183	phosphatidylcholine synthase activity
AVI53_RS11675	COG0456	acetyltransferase
AVI53_RS11685	COG0084	hydrolase, TatD family'
AVI53_RS11695	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AVI53_RS11755	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AVI53_RS11790	COG3385	transposase activity
AVI53_RS11800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AVI53_RS11810	COG1773	rubredoxin
AVI53_RS11815	COG1981	membrane
AVI53_RS11820	COG0316	Belongs to the HesB IscA family
AVI53_RS11830	COG3385	transposase activity
AVI53_RS11860	COG0084	hydrolase, TatD family'
AVI53_RS11875	COG1028	Short-chain dehydrogenase reductase Sdr
AVI53_RS11890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVI53_RS11895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVI53_RS11910	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS11915	COG3385	transposase activity
AVI53_RS11935	COG0833	amino acid
AVI53_RS11945	COG3385	transposase activity
AVI53_RS11950	COG3385	transposase activity
AVI53_RS11960	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS11985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AVI53_RS11995	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS12015	COG3385	transposase activity
AVI53_RS12030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVI53_RS12085	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AVI53_RS12115	COG2205	protein histidine kinase activity
AVI53_RS12125	COG0500	methyltransferase
AVI53_RS12155	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS12165	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS12170	COG0308	aminopeptidase N
AVI53_RS12180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AVI53_RS12185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AVI53_RS12190	COG3385	transposase activity
AVI53_RS12210	COG1113	amino acid transport
AVI53_RS12235	COG0837	glucose binding
AVI53_RS12245	COG3852	Histidine kinase
AVI53_RS12255	COG1677	Flagellar hook-basal body complex protein FliE
AVI53_RS12265	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVI53_RS12310	COG2009	succinate dehydrogenase
AVI53_RS12315	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AVI53_RS12320	COG1053	succinate dehydrogenase
AVI53_RS12325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AVI53_RS12340	COG0045	succinate-CoA ligase (ADP-forming) activity
AVI53_RS12360	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS12385	COG1918	ferrous iron import across plasma membrane
AVI53_RS12390	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AVI53_RS12400	COG0625	glutathione transferase activity
AVI53_RS12405	COG2969	positive regulation of protein catabolic process
AVI53_RS12410	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AVI53_RS12415	COG0792	nuclease activity
AVI53_RS12425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVI53_RS12430	COG0142	geranyltranstransferase activity
AVI53_RS12435	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AVI53_RS12445	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AVI53_RS12450	COG0840	transmembrane signaling receptor activity
AVI53_RS12460	COG1509	lysine 2,3-aminomutase activity
AVI53_RS12465	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AVI53_RS12470	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AVI53_RS12495	COG0438	transferase activity, transferring glycosyl groups
AVI53_RS12500	COG0436	Aminotransferase
AVI53_RS12505	COG0556	nucleotide-excision repair
AVI53_RS12515	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AVI53_RS12525	COG1086	Polysaccharide biosynthesis protein
AVI53_RS12530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVI53_RS12535	COG1083	cytidylyl-transferase
AVI53_RS12545	COG2089	acid synthase
AVI53_RS12565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AVI53_RS12575	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AVI53_RS12590	COG0072	phenylalanine-tRNA ligase activity
AVI53_RS12595	COG0776	regulation of translation
AVI53_RS12605	COG1881	PFAM PEBP family protein
AVI53_RS12630	COG0069	glutamate synthase activity
AVI53_RS12655	COG3385	transposase activity
AVI53_RS12670	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS12685	COG2818	Glycosylase
AVI53_RS12695	COG2963	transposase activity
AVI53_RS12755	COG0728	peptidoglycan biosynthetic process
AVI53_RS12760	COG0196	riboflavin kinase activity
AVI53_RS12765	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS12770	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AVI53_RS12775	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AVI53_RS12780	COG1047	Peptidyl-prolyl cis-trans
AVI53_RS12785	COG2271	Major facilitator Superfamily
AVI53_RS12795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AVI53_RS12800	COG0840	transmembrane signaling receptor activity
AVI53_RS12810	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS12845	COG1051	belongs to the nudix hydrolase family
AVI53_RS12870	COG3385	transposase activity
AVI53_RS12885	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS12920	COG0735	belongs to the Fur family
AVI53_RS12925	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AVI53_RS12935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AVI53_RS12940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AVI53_RS12945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AVI53_RS12975	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS13000	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AVI53_RS13045	COG0835	chemotaxis
AVI53_RS13045	COG0784	Response regulator, receiver
AVI53_RS13070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AVI53_RS13075	COG2814	Major facilitator Superfamily
AVI53_RS13080	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AVI53_RS13085	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AVI53_RS13105	COG2963	transposase activity
AVI53_RS13110	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS13145	COG0307	riboflavin synthase, alpha
AVI53_RS13155	COG0189	ligase activity
AVI53_RS13175	COG2801	Transposase and inactivated derivatives
AVI53_RS13180	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS13190	COG3385	transposase activity
AVI53_RS13195	COG2177	Part of the ABC transporter FtsEX involved in
AVI53_RS13200	COG2884	Cell division ATP-binding protein ftsE
AVI53_RS13215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVI53_RS13220	COG3385	transposase activity
AVI53_RS13235	COG0205	6-phosphofructokinase activity
AVI53_RS13245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVI53_RS13265	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS13280	COG0546	phosphoglycolate phosphatase activity
AVI53_RS13295	COG2350	Protein conserved in bacteria
AVI53_RS13300	COG2917	probably involved in intracellular septation
AVI53_RS13305	COG0009	L-threonylcarbamoyladenylate synthase
AVI53_RS13315	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AVI53_RS13350	COG0739	heme binding
AVI53_RS13355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AVI53_RS13370	COG0670	Belongs to the BI1 family
AVI53_RS13375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVI53_RS13390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVI53_RS13415	COG2963	transposase activity
AVI53_RS13430	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS13445	COG2801	Transposase and inactivated derivatives
AVI53_RS13460	COG2963	transposase activity
AVI53_RS13485	COG3240	lipase activity
AVI53_RS13490	COG3385	transposase activity
AVI53_RS13510	COG0742	ribosomal rna small subunit methyltransferase
AVI53_RS13515	COG1760	l-serine dehydratase
AVI53_RS13545	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AVI53_RS13550	COG3273	potassium ion transport
AVI53_RS13550	COG0471	metal ion transport
AVI53_RS13570	COG3385	transposase activity
AVI53_RS13595	COG0166	Belongs to the GPI family
AVI53_RS13605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AVI53_RS13610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AVI53_RS13635	COG3385	transposase activity
AVI53_RS13645	COG2801	Transposase and inactivated derivatives
AVI53_RS13660	COG3385	transposase activity
AVI53_RS13665	COG2814	Major facilitator Superfamily
AVI53_RS13670	COG0156	8-amino-7-oxononanoate synthase activity
AVI53_RS13680	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVI53_RS13715	COG2801	Transposase and inactivated derivatives
AVI53_RS13730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AVI53_RS13740	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AVI53_RS13745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AVI53_RS13755	COG2183	response to ionizing radiation
AVI53_RS13775	COG2801	Transposase and inactivated derivatives
AVI53_RS13780	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AVI53_RS13785	COG2871	sodium ion transport
AVI53_RS13790	COG1438	arginine binding
AVI53_RS13840	COG2801	Transposase and inactivated derivatives
AVI53_RS13865	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS13870	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVI53_RS13875	COG0154	amidase activity
AVI53_RS13880	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVI53_RS13885	COG1077	Cell shape determining protein MreB Mrl
AVI53_RS13890	COG1792	Involved in formation and maintenance of cell shape
AVI53_RS13900	COG0424	maF-like protein
AVI53_RS13905	COG1530	ribonuclease E activity
AVI53_RS13915	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AVI53_RS13925	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS13930	COG3385	transposase activity
AVI53_RS13935	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS13945	COG2171	N-acyltransferase activity
AVI53_RS13950	COG0252	asparaginase activity
AVI53_RS13955	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AVI53_RS13965	COG0052	Belongs to the universal ribosomal protein uS2 family
AVI53_RS13970	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AVI53_RS13975	COG0528	UMP kinase activity
AVI53_RS13980	COG0233	cytoplasmic translational termination
AVI53_RS13985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AVI53_RS13990	COG0575	Belongs to the CDS family
AVI53_RS14015	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AVI53_RS14030	COG3425	synthase
AVI53_RS14050	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVI53_RS14055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVI53_RS14060	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVI53_RS14065	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVI53_RS14070	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AVI53_RS14080	COG0825	malonyl-CoA metabolic process
AVI53_RS14085	COG0037	tRNA processing
AVI53_RS14090	COG0659	secondary active sulfate transmembrane transporter activity
AVI53_RS14095	COG3385	transposase activity
AVI53_RS14110	COG3385	transposase activity
AVI53_RS14115	COG3385	transposase activity
AVI53_RS14120	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS14155	COG2223	nitrite transmembrane transporter activity
AVI53_RS14170	COG3385	transposase activity
AVI53_RS14190	COG2801	Transposase and inactivated derivatives
AVI53_RS14205	COG3385	transposase activity
AVI53_RS14290	COG0351	phosphomethylpyrimidine kinase
AVI53_RS14315	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AVI53_RS14325	COG1566	PFAM secretion protein HlyD family protein
AVI53_RS14330	COG2814	Major facilitator Superfamily
AVI53_RS14335	COG1538	Outer membrane efflux protein
AVI53_RS14340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVI53_RS14350	COG2197	response regulator
AVI53_RS14355	COG0322	excinuclease ABC activity
AVI53_RS14385	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS14455	COG2801	Transposase and inactivated derivatives
AVI53_RS14470	COG3385	transposase activity
AVI53_RS14490	COG0656	L-ascorbic acid biosynthetic process
AVI53_RS14500	COG0477	Major facilitator Superfamily
AVI53_RS14505	COG0235	Class ii aldolase
AVI53_RS14515	COG0626	cystathionine gamma-synthase activity
AVI53_RS14525	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AVI53_RS14540	COG0544	peptidyl-prolyl cis-trans isomerase activity
AVI53_RS14545	COG0740	serine-type endopeptidase activity
AVI53_RS14550	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AVI53_RS14555	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVI53_RS14570	COG1560	Kdo2-lipid A biosynthetic process
AVI53_RS14575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AVI53_RS14585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI53_RS14590	COG2274	protein secretion by the type I secretion system
AVI53_RS14595	COG2274	protein secretion by the type I secretion system
AVI53_RS14600	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AVI53_RS14610	COG1686	Belongs to the peptidase S11 family
AVI53_RS14640	COG3385	transposase activity
AVI53_RS14645	COG2801	Transposase and inactivated derivatives
AVI53_RS14690	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS14695	COG0187	DNA topoisomerase II activity
AVI53_RS14710	COG3385	transposase activity
AVI53_RS14720	COG3385	transposase activity
AVI53_RS14765	COG0776	regulation of translation
AVI53_RS14770	COG0494	nUDIX hydrolase
AVI53_RS14775	COG3385	transposase activity
AVI53_RS14785	COG0039	L-malate dehydrogenase activity
AVI53_RS14790	COG1538	Outer membrane efflux protein
AVI53_RS14795	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AVI53_RS14800	COG3150	esterase
AVI53_RS14805	COG4988	ABC transporter
AVI53_RS14810	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AVI53_RS14825	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS14840	COG3104	oligopeptide transport
AVI53_RS14845	COG3385	transposase activity
AVI53_RS14850	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS14880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AVI53_RS14900	COG1058	Belongs to the CinA family
AVI53_RS14900	COG1546	Belongs to the CinA family
AVI53_RS14935	COG3385	transposase activity
AVI53_RS14955	COG4948	Mandelate Racemase Muconate Lactonizing
AVI53_RS14965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVI53_RS14970	COG0450	alkyl hydroperoxide reductase
AVI53_RS14980	COG0500	methyltransferase
AVI53_RS15010	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS15035	COG3385	transposase activity
AVI53_RS15050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVI53_RS15065	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVI53_RS15070	COG0531	amino acid
AVI53_RS15075	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS15080	COG0531	amino acid
AVI53_RS15085	COG2801	Transposase and inactivated derivatives
AVI53_RS15145	COG3385	transposase activity
AVI53_RS15180	COG2801	Transposase and inactivated derivatives
AVI53_RS15210	COG0358	DNA primase activity
AVI53_RS15215	COG1610	YqeY-like protein
AVI53_RS15220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AVI53_RS15225	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AVI53_RS15230	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AVI53_RS15250	COG3385	transposase activity
AVI53_RS15255	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS15275	COG1621	beta-fructofuranosidase activity
AVI53_RS15295	COG0259	pyridoxamine-phosphate oxidase activity
AVI53_RS15300	COG0589	response to stress
AVI53_RS15310	COG1228	amidohydrolase
AVI53_RS15320	COG2986	histidine ammonia-lyase
AVI53_RS15345	COG3385	transposase activity
AVI53_RS15370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AVI53_RS15375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVI53_RS15385	COG3956	TIGRFAM MazG family protein
AVI53_RS15390	COG3956	TIGRFAM MazG family protein
AVI53_RS15400	COG0563	adenylate kinase activity
AVI53_RS15405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVI53_RS15410	COG2223	nitrite transmembrane transporter activity
AVI53_RS15425	COG1278	Cold shock
AVI53_RS15430	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVI53_RS15435	COG0542	response to heat
AVI53_RS15440	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AVI53_RS15460	COG0492	ferredoxin-NADP+ reductase activity
AVI53_RS15465	COG1674	ftsk spoiiie
AVI53_RS15480	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AVI53_RS15485	COG1104	cysteine desulfurase activity
AVI53_RS15495	COG0105	UTP biosynthetic process
AVI53_RS15500	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AVI53_RS15520	COG0124	histidyl-tRNA synthetase
AVI53_RS15530	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVI53_RS15535	COG1160	GTP binding
AVI53_RS15550	COG1192	Involved in chromosome partitioning
AVI53_RS15560	COG0835	chemotaxis
AVI53_RS15590	COG2201	protein-glutamate methylesterase activity
AVI53_RS15600	COG1530	ribonuclease E activity
AVI53_RS15610	COG2918	glutathione biosynthetic process
AVI53_RS15615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVI53_RS15620	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AVI53_RS15625	COG0632	four-way junction helicase activity
AVI53_RS15635	COG0811	peptide transport
AVI53_RS15650	COG0823	Involved in the tonB-independent uptake of proteins
AVI53_RS15660	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AVI53_RS15665	COG0602	queuosine metabolic process
AVI53_RS15685	COG1570	exodeoxyribonuclease VII activity
AVI53_RS15690	COG1131	(ABC) transporter
AVI53_RS15695	COG0842	Transport permease protein
AVI53_RS15705	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS15715	COG0442	prolyl-tRNA aminoacylation
AVI53_RS15720	COG3385	transposase activity
AVI53_RS15745	COG3385	transposase activity
AVI53_RS15785	COG3385	transposase activity
AVI53_RS15790	COG2204	response regulator
AVI53_RS15810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVI53_RS15815	COG0616	signal peptide processing
AVI53_RS15820	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AVI53_RS15900	COG3385	transposase activity
AVI53_RS15905	COG1012	belongs to the aldehyde dehydrogenase family
AVI53_RS15915	COG0784	Response regulator, receiver
AVI53_RS15915	COG2205	protein histidine kinase activity
AVI53_RS15915	COG5002	protein histidine kinase activity
AVI53_RS15930	COG2801	Transposase and inactivated derivatives
AVI53_RS15945	COG0183	Belongs to the thiolase family
AVI53_RS15950	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVI53_RS15950	COG1024	Enoyl-CoA hydratase
AVI53_RS15965	COG1472	Belongs to the glycosyl hydrolase 3 family
AVI53_RS15970	COG0668	transmembrane transport
AVI53_RS15975	COG0598	Magnesium transport protein CorA
AVI53_RS15980	COG0318	PFAM AMP-dependent synthetase and ligase
AVI53_RS15990	COG0527	aspartate kinase activity
AVI53_RS15990	COG0460	homoserine dehydrogenase
AVI53_RS16000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AVI53_RS16015	COG2801	Transposase and inactivated derivatives
AVI53_RS16020	COG2801	Transposase and inactivated derivatives
AVI53_RS16030	COG2814	Major facilitator Superfamily
AVI53_RS16035	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVI53_RS16140	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVI53_RS16165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVI53_RS16175	COG0564	pseudouridine synthase activity
AVI53_RS16180	COG1335	isochorismatase
AVI53_RS16185	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AVI53_RS16220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AVI53_RS16240	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS16260	COG2826	transposase and inactivated derivatives, IS30 family
AVI53_RS16270	COG0288	reversible hydration of carbon dioxide
AVI53_RS16275	COG2814	Major facilitator Superfamily
AVI53_RS16290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVI53_RS16295	COG0795	lipopolysaccharide-transporting ATPase activity
AVI53_RS16305	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AVI53_RS16325	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVI53_RS16565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVI53_RS16575	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVI53_RS16670	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI53_RS16670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI53_RS17385	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AVI53_RS17515	COG2801	Transposase and inactivated derivatives
AVI53_RS17735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVI53_RS17760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia