locus-tag	class	description
GW538_RS00010	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GW538_RS00015	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GW538_RS00020	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GW538_RS00025	ENOG4105VG0	50S ribosomal protein l34
GW538_RS00035	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GW538_RS00040	ENOG4107QJE	Chromosome Partitioning Protein
GW538_RS00045	ENOG4105FA0	parb-like partition protein
GW538_RS00055	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GW538_RS00060	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GW538_RS00065	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GW538_RS00070	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GW538_RS00075	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GW538_RS00080	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GW538_RS00085	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GW538_RS00095	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GW538_RS00100	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GW538_RS00105	ENOG4108BUD	transposase
GW538_RS00145	ENOG4105D1F	ATP-binding protein
GW538_RS00165	ENOG4108SER	Transposase
GW538_RS00175	ENOG4105F9F	transposase
GW538_RS00190	ENOG4105C2X	Arabinose 5-phosphate isomerase
GW538_RS00215	ENOG4107RDB	Major Facilitator
GW538_RS00220	ENOG4105E2S	oxidase) subunit II
GW538_RS00225	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GW538_RS00230	ENOG4105CCU	oxidase (Subunit III)
GW538_RS00235	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
GW538_RS00240	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GW538_RS00265	ENOG4107RCM	Releases the N-terminal proline from various substrates (By similarity)
GW538_RS00275	ENOG4108SER	Transposase
GW538_RS00305	ENOG4108SER	Transposase
GW538_RS00335	ENOG4105EMU	Dehydrogenase
GW538_RS00355	ENOG4105BZS	acriflavin resistance protein
GW538_RS00365	ENOG4105D7Z	glutathione synthase
GW538_RS00370	ENOG4105CSA	Coproporphyrinogen iii oxidase
GW538_RS00375	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GW538_RS00380	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GW538_RS00385	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GW538_RS00395	ENOG4105E2X	shikimate dehydrogenase
GW538_RS00415	ENOG4108UJU	UPF0301 protein
GW538_RS00420	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GW538_RS00430	ENOG4105DFA	alanine racemase domain protein
GW538_RS00435	ENOG4105II7	pyrroline-5-carboxylate reductase
GW538_RS00450	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GW538_RS00455	ENOG4105C6K	Malic enzyme
GW538_RS00465	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GW538_RS00475	ENOG4105EMU	Dehydrogenase
GW538_RS00505	ENOG4105KJF	protein tyrosine phosphatase
GW538_RS00510	ENOG4105DAY	polysaccharide export protein
GW538_RS00520	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GW538_RS00535	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
GW538_RS00545	ENOG4107SJB	teichoic acid biosynthesis
GW538_RS00560	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GW538_RS00565	ENOG4105JNK	Glycosyl transferase (Group 1
GW538_RS00580	ENOG4105D3Q	Sugar transferase
GW538_RS00590	ENOG4108WHA	ompa motb domain protein
GW538_RS00595	ENOG4105VEQ	Cold shock protein
GW538_RS00600	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GW538_RS00605	ENOG4105F9F	transposase
GW538_RS00610	ENOG4105C0H	protease
GW538_RS00615	ENOG4105F44	Two component transcriptional regulator, winged helix family
GW538_RS00625	ENOG4108VIA	integral membrane protein
GW538_RS00635	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GW538_RS00685	ENOG4105ETT	transcriptional Regulator, LysR family
GW538_RS00700	ENOG4105C4R	Atp-dependent dna helicase
GW538_RS00710	ENOG4105E5D	amino acid
GW538_RS00720	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GW538_RS00730	ENOG4105CEY	Amp-dependent synthetase and ligase
GW538_RS00745	ENOG4105BZS	acriflavin resistance protein
GW538_RS00750	ENOG410624X	efflux transporter, rnd family, mfp subunit
GW538_RS00800	ENOG4105MIR	Phenylalanine 4-monooxygenase
GW538_RS00810	ENOG4107PBV	potassium channel
GW538_RS00815	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GW538_RS00820	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GW538_RS00825	ENOG4105VW4	glutaredoxin 3
GW538_RS00830	ENOG4105C72	UPF0176 protein
GW538_RS00845	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GW538_RS00850	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GW538_RS00865	ENOG4105C4R	Atp-dependent dna helicase
GW538_RS00880	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GW538_RS00920	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GW538_RS00950	ENOG4105WPN	DNA integration recombination invertion protein
GW538_RS00960	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GW538_RS00970	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GW538_RS00995	ENOG4108SER	Transposase
GW538_RS01025	ENOG4105HBR	Rna-binding protein
GW538_RS01035	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GW538_RS01040	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GW538_RS01045	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GW538_RS01050	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GW538_RS01055	ENOG4107QSN	dihydrolipoamide acetyltransferase
GW538_RS01060	ENOG4107QN2	dihydrolipoyl dehydrogenase
GW538_RS01065	ENOG4105HDD	phospholipase
GW538_RS01080	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GW538_RS01085	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GW538_RS01090	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GW538_RS01095	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GW538_RS01100	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GW538_RS01110	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GW538_RS01115	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GW538_RS01120	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GW538_RS01125	ENOG4105C12	Phosphoribosylglycinamide synthetase
GW538_RS01130	ENOG4107RAQ	aminopeptidase
GW538_RS01150	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
GW538_RS01155	ENOG4107QTZ	amino acid
GW538_RS01175	ENOG4105CJB	Exodeoxyribonuclease I
GW538_RS01185	ENOG4108UMI	ABC transporter, permease
GW538_RS01190	ENOG4105D01	(LipO)protein
GW538_RS01205	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GW538_RS01210	ENOG4105EA8	2-Nitropropane dioxygenase
GW538_RS01215	ENOG4105DQR	SNARE associated Golgi
GW538_RS01220	ENOG4108JU6	CBS domain protein
GW538_RS01225	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GW538_RS01230	ENOG4105H2K	paraquat-inducible protein a
GW538_RS01260	ENOG4107QJT	sodium dicarboxylate symporter
GW538_RS01265	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GW538_RS01270	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
GW538_RS01290	ENOG4108SER	Transposase
GW538_RS01295	ENOG4105DUX	Transporter
GW538_RS01345	ENOG4108SER	Transposase
GW538_RS01365	ENOG4105F9F	transposase
GW538_RS01380	ENOG4108SER	Transposase
GW538_RS01400	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GW538_RS01425	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
GW538_RS01435	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
GW538_RS01445	ENOG4105EYA	deoxyribonuclease
GW538_RS01455	ENOG4105CUZ	uba thif-type nad fad binding protein
GW538_RS01515	ENOG4108Z0R	Transferase
GW538_RS01540	ENOG4108SER	Transposase
GW538_RS01550	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GW538_RS01560	ENOG4105VCQ	rubredoxin
GW538_RS01565	ENOG4108YXA	Membrane
GW538_RS01570	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GW538_RS01580	ENOG4108SER	Transposase
GW538_RS01600	ENOG4107QRG	dna polymerase iii
GW538_RS01610	ENOG4105F8V	Hydrolase, tatD family
GW538_RS01630	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
GW538_RS01640	ENOG4107RJ1	sodium solute
GW538_RS01645	ENOG4107SCR	N-acetylneuraminate lyase
GW538_RS01660	ENOG4105F9F	transposase
GW538_RS01665	ENOG4108SER	Transposase
GW538_RS01675	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GW538_RS01685	ENOG4108IQI	permease
GW538_RS01695	ENOG4108SER	Transposase
GW538_RS01705	ENOG4108SER	Transposase
GW538_RS01715	ENOG4105F9F	transposase
GW538_RS01735	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GW538_RS01745	ENOG4105F9F	transposase
GW538_RS01770	ENOG4108SER	Transposase
GW538_RS01795	ENOG4105CSH	Transporter
GW538_RS01840	ENOG4108BUD	transposase
GW538_RS01875	ENOG4105BZU	Histidine kinase
GW538_RS01900	ENOG410607W	Transposase
GW538_RS01915	ENOG4105F9F	transposase
GW538_RS01925	ENOG4105F9F	transposase
GW538_RS01930	ENOG4105CD8	aminopeptidase N
GW538_RS01940	ENOG4107QNJ	CoA-transferase subunit B
GW538_RS01945	ENOG4107QP7	CoA-transferase subunit A
GW538_RS01950	ENOG4108SER	Transposase
GW538_RS01960	ENOG4108NVR	Methyl-accepting chemotaxis
GW538_RS01970	ENOG4105C85	amino acid
GW538_RS01995	ENOG4105CHC	glucokinase (EC 2.7.1.2)
GW538_RS02005	ENOG4105BZU	Histidine kinase
GW538_RS02015	ENOG4105X6K	flagellar hook-basal body complex protein fliE
GW538_RS02020	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GW538_RS02025	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GW538_RS02035	ENOG4108JIR	Flagellum-specific ATP synthase
GW538_RS02065	ENOG4105BZN	citrate synthase
GW538_RS02070	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GW538_RS02075	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GW538_RS02080	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GW538_RS02085	ENOG4105E33	succinate dehydrogenase
GW538_RS02090	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GW538_RS02095	ENOG4105C7S	Dehydrogenase
GW538_RS02100	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GW538_RS02105	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GW538_RS02115	ENOG4105C8Q	Methyl-accepting chemotaxis
GW538_RS02120	ENOG4105F9F	transposase
GW538_RS02140	ENOG4105CE1	Ferrous iron transport protein b
GW538_RS02145	ENOG4105XFK	Ferrous iron transport protein A
GW538_RS02150	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GW538_RS02155	ENOG4108UJD	30S ribosomal protein S9
GW538_RS02160	ENOG4107MKT	Stringent starvation protein a
GW538_RS02165	ENOG4105KB2	stringent starvation protein b
GW538_RS02170	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GW538_RS02175	ENOG41082RQ	UPF0102 protein
GW538_RS02185	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GW538_RS02190	ENOG4105EAH	synthase
GW538_RS02195	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GW538_RS02200	ENOG4105K46	50S ribosomal protein l27
GW538_RS02205	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GW538_RS02210	ENOG4108N3W	hemolysin secretion protein
GW538_RS02220	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GW538_RS02225	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GW538_RS02230	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
GW538_RS02255	ENOG4105CG5	Glycosyl transferase (Group 1
GW538_RS02265	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GW538_RS02285	ENOG4105C5E	polysaccharide biosynthesis protein
GW538_RS02290	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GW538_RS02295	ENOG4105F0R	Cytidylyltransferase
GW538_RS02325	ENOG4105C22	threonyL-tRNA synthetase
GW538_RS02330	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GW538_RS02335	ENOG41082NX	50s ribosomal protein l35
GW538_RS02350	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GW538_RS02355	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GW538_RS02390	ENOG4105CBC	glutamate synthase
GW538_RS02420	ENOG4108SER	Transposase
GW538_RS02450	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GW538_RS02510	ENOG4105CJR	Integral membrane protein (MviN
GW538_RS02515	ENOG4105DTN	riboflavin biosynthesis protein ribF
GW538_RS02520	ENOG4105F9F	transposase
GW538_RS02525	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GW538_RS02530	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GW538_RS02535	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GW538_RS02550	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GW538_RS02555	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GW538_RS02565	ENOG4105F9F	transposase
GW538_RS02600	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GW538_RS02625	ENOG4108SER	Transposase
GW538_RS02640	ENOG4105F9F	transposase
GW538_RS02670	ENOG4105MYN	Zinc uptake regulation protein
GW538_RS02675	ENOG4105F0N	pyrophosphate phospho-hydrolase
GW538_RS02685	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GW538_RS02690	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GW538_RS02695	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GW538_RS02705	ENOG4105CA9	Pyruvate kinase
GW538_RS02710	ENOG4105D2N	Aldolase
GW538_RS02725	ENOG4105F9F	transposase
GW538_RS02750	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
GW538_RS02830	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GW538_RS02835	ENOG4105E5M	Multidrug resistance protein D
GW538_RS02840	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
GW538_RS02845	ENOG4105CRK	lysyL-tRNA synthetase
GW538_RS02865	ENOG4105F9F	transposase
GW538_RS02900	ENOG4108R6K	riboflavin synthase, subunit alpha
GW538_RS02905	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GW538_RS02925	ENOG4105F9F	transposase
GW538_RS02930	ENOG4108SER	Transposase
GW538_RS02935	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GW538_RS02940	ENOG4105CAK	Cell division ATP-binding protein ftsE
GW538_RS02960	ENOG4108SER	Transposase
GW538_RS02980	ENOG4105CTQ	phosphohexokinase
GW538_RS02990	ENOG4105DFU	Cell wall formation (By similarity)
GW538_RS02995	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GW538_RS03005	ENOG4108NVR	Methyl-accepting chemotaxis
GW538_RS03010	ENOG4105F9F	transposase
GW538_RS03025	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
GW538_RS03040	ENOG4105K9H	YciI-like protein
GW538_RS03045	ENOG4107835	probably involved in intracellular septation (By similarity)
GW538_RS03050	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GW538_RS03060	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GW538_RS03065	ENOG4105FE9	pseudouridine synthase
GW538_RS03100	ENOG4105DR5	peptidase
GW538_RS03105	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GW538_RS03115	ENOG4108MN8	Membrane
GW538_RS03120	ENOG4107RE1	Inosine-guanosine kinase
GW538_RS03135	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GW538_RS03175	ENOG4105F9F	transposase
GW538_RS03190	ENOG4105DQ6	Transposase
GW538_RS03195	ENOG4105DQ6	Transposase
GW538_RS03235	ENOG4108SER	Transposase
GW538_RS03255	ENOG4106H78	methyltransferase
GW538_RS03260	ENOG4105EJQ	L-serine dehydratase
GW538_RS03290	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GW538_RS03320	ENOG4108SER	Transposase
GW538_RS03345	ENOG4107QP8	phosphohexose isomerase
GW538_RS03350	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GW538_RS03355	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GW538_RS03360	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
GW538_RS03390	ENOG4108SER	Transposase
GW538_RS03410	ENOG4108SER	Transposase
GW538_RS03415	ENOG4105F27	Major Facilitator
GW538_RS03420	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GW538_RS03435	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
GW538_RS03445	ENOG4107R88	Chemotaxis protein (CheV)
GW538_RS03485	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GW538_RS03495	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GW538_RS03500	ENOG4105D9N	nucleoside
GW538_RS03510	ENOG4105BZM	domain protein
GW538_RS03530	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GW538_RS03535	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
GW538_RS03540	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GW538_RS03595	ENOG410607W	Transposase
GW538_RS03610	ENOG4105F9F	transposase
GW538_RS03615	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GW538_RS03620	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GW538_RS03625	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GW538_RS03635	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GW538_RS03645	ENOG4108Z03	MAF-like protein
GW538_RS03650	ENOG4105C03	ribonuclease
GW538_RS03660	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GW538_RS03670	ENOG4105F9F	transposase
GW538_RS03675	ENOG4108SER	Transposase
GW538_RS03680	ENOG4105F9F	transposase
GW538_RS03690	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GW538_RS03695	ENOG4105HDK	L-asparaginase
GW538_RS03700	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GW538_RS03705	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GW538_RS03710	ENOG4105CE9	30S ribosomal protein S2
GW538_RS03715	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GW538_RS03720	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GW538_RS03725	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GW538_RS03730	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GW538_RS03735	ENOG4105KNE	Phosphatidate cytidylyltransferase
GW538_RS03760	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
GW538_RS03775	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
GW538_RS03785	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GW538_RS03795	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GW538_RS03800	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GW538_RS03805	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GW538_RS03810	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GW538_RS03815	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GW538_RS03820	ENOG4105C0B	DNA polymerase III (alpha subunit)
GW538_RS03825	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GW538_RS03830	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GW538_RS03835	ENOG4105CHH	sulfate transporter
GW538_RS03840	ENOG4108SER	Transposase
GW538_RS03855	ENOG4108SER	Transposase
GW538_RS03860	ENOG4108SER	Transposase
GW538_RS03865	ENOG4105F9F	transposase
GW538_RS03900	ENOG4105EYM	Major Facilitator superfamily
GW538_RS03915	ENOG4108SER	Transposase
GW538_RS03945	ENOG4108SER	Transposase
GW538_RS03980	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GW538_RS03995	ENOG4108ETH	Formylglycinamide ribotide synthetase
GW538_RS04025	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GW538_RS04035	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GW538_RS04065	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
GW538_RS04075	ENOG4105CW7	secretion protein, HlyD family
GW538_RS04080	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GW538_RS04085	ENOG4105DFG	type I secretion outer membrane protein
GW538_RS04090	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GW538_RS04100	ENOG4105WH1	Two component transcriptional regulator luxr family
GW538_RS04135	ENOG4105F9F	transposase
GW538_RS04225	ENOG4108SER	Transposase
GW538_RS04255	ENOG4105CSH	Transporter
GW538_RS04260	ENOG4105MP9	class II Aldolase
GW538_RS04270	ENOG4105C28	cystathionine
GW538_RS04280	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GW538_RS04295	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GW538_RS04300	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GW538_RS04310	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GW538_RS04315	ENOG4105K70	DNA-binding protein
GW538_RS04325	ENOG4105D1S	lipid A biosynthesis
GW538_RS04330	ENOG41082CG	Protein CrcB homolog
GW538_RS04335	ENOG4105BZU	Histidine kinase
GW538_RS04340	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
GW538_RS04345	ENOG4108JJA	ABC, transporter
GW538_RS04350	ENOG4108JJA	ABC, transporter
GW538_RS04355	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GW538_RS04360	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GW538_RS04365	ENOG4105DZ1	carboxypeptidase
GW538_RS04395	ENOG4108SER	Transposase
GW538_RS04440	ENOG4105F9F	transposase
GW538_RS04445	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GW538_RS04455	ENOG4108SER	Transposase
GW538_RS04465	ENOG4108SER	Transposase
GW538_RS04515	ENOG4105K70	DNA-binding protein
GW538_RS04525	ENOG4108SER	Transposase
GW538_RS04535	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GW538_RS04540	ENOG4105DFG	type I secretion outer membrane protein
GW538_RS04545	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GW538_RS04550	ENOG4105IPS	esterase
GW538_RS04555	ENOG4108JJ9	ABC, transporter
GW538_RS04560	ENOG4108JJ8	(ABC) transporter
GW538_RS04590	ENOG4105DUX	Transporter
GW538_RS04595	ENOG4108SER	Transposase
GW538_RS04600	ENOG4105F9F	transposase
GW538_RS04650	ENOG4105CEV	competence damage-inducible protein
GW538_RS04675	ENOG4108SER	Transposase
GW538_RS04690	ENOG4105CXK	mandelate racemase muconate lactonizing
GW538_RS04695	ENOG4105C26	Dehydrogenase
GW538_RS04700	ENOG4105CK7	Sodium proline symporter
GW538_RS04705	ENOG4105D3R	alkyl hydroperoxide reductase
GW538_RS04710	ENOG4108YGX	
GW538_RS04720	ENOG4108SER	Transposase
GW538_RS04740	ENOG4105F9F	transposase
GW538_RS04760	ENOG4108SER	Transposase
GW538_RS04780	ENOG4105C0H	protease
GW538_RS04795	ENOG4105D6Z	AFG1 family ATPase
GW538_RS04805	ENOG4105F9F	transposase
GW538_RS04870	ENOG4108SER	Transposase
GW538_RS04925	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GW538_RS04930	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GW538_RS04935	ENOG4105KTH	gatB Yqey
GW538_RS04940	ENOG4105VCC	30S ribosomal protein S21
GW538_RS04945	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GW538_RS04950	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GW538_RS04965	ENOG4108SER	Transposase
GW538_RS04975	ENOG4108SER	Transposase
GW538_RS04980	ENOG4105F9F	transposase
GW538_RS05000	ENOG4107R3K	hydrolase
GW538_RS05025	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GW538_RS05030	ENOG41081QV	Universal stress protein
GW538_RS05040	ENOG4105CI2	imidazolone-5-propionate hydrolase
GW538_RS05050	ENOG4105C84	Histidine ammonia-lyase
GW538_RS05085	ENOG4108SER	Transposase
GW538_RS05105	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GW538_RS05110	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GW538_RS05120	ENOG4105DXN	mazG family
GW538_RS05125	ENOG4105DXN	mazG family
GW538_RS05130	ENOG4108URH	decarboxylase
GW538_RS05135	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GW538_RS05140	ENOG41080RH	Thioredoxin
GW538_RS05145	ENOG4105EYM	Major Facilitator superfamily
GW538_RS05160	ENOG4105VEQ	Cold shock protein
GW538_RS05165	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GW538_RS05170	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GW538_RS05175	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GW538_RS05185	ENOG4105F9F	transposase
GW538_RS05195	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GW538_RS05200	ENOG4105C3M	thioredoxin reductase
GW538_RS05215	ENOG4105ECY	inositol monophosphatase
GW538_RS05220	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
GW538_RS05225	ENOG4105C3J	Cysteine desulfurase
GW538_RS05235	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GW538_RS05240	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GW538_RS05260	ENOG4105CUT	histidyl-tRNA synthetase
GW538_RS05270	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GW538_RS05275	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GW538_RS05300	ENOG4107QJE	Chromosome Partitioning Protein
GW538_RS05310	ENOG4108V3W	Chemotaxis protein, CheW
GW538_RS05325	ENOG4105F9F	transposase
GW538_RS05345	ENOG4107YTP	response regulator receiver protein
GW538_RS05350	ENOG4105EI2	Pseudouridine synthase
GW538_RS05355	ENOG4105C03	ribonuclease
GW538_RS05365	ENOG4105D9M	gamma-glutamylcysteine synthetase
GW538_RS05370	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GW538_RS05375	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GW538_RS05380	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GW538_RS05390	ENOG4105E02	MotA TolQ exbB proton channel
GW538_RS05395	ENOG4105M8F	Biopolymer transport protein exbD tolR
GW538_RS05405	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GW538_RS05410	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GW538_RS05415	ENOG4105UFD	tol-pal system protein YbgF
GW538_RS05420	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GW538_RS05440	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GW538_RS05445	ENOG4105DA5	(ABC) transporter
GW538_RS05450	ENOG4105E3A	(ABC) transporter
GW538_RS05460	ENOG4105F9F	transposase
GW538_RS05470	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GW538_RS05475	ENOG4108SER	Transposase
GW538_RS05495	ENOG4108SER	Transposase
GW538_RS05540	ENOG4108SER	Transposase
GW538_RS05565	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GW538_RS05570	ENOG4105ERU	peptidase
GW538_RS05575	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GW538_RS05605	ENOG4105CBS	Chea signal transduction histidine kinase
GW538_RS05625	ENOG4108SER	Transposase
GW538_RS05650	ENOG4108SER	Transposase
GW538_RS05655	ENOG4105C26	Dehydrogenase
GW538_RS05665	ENOG4105BZU	Histidine kinase
GW538_RS05690	ENOG4105CHU	acetyl-coa acetyltransferase
GW538_RS05710	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
GW538_RS05715	ENOG4105D64	Mechanosensitive ion channel
GW538_RS05720	ENOG4105D7N	magnesium and cobalt transport protein CorA
GW538_RS05725	ENOG4105CEY	Amp-dependent synthetase and ligase
GW538_RS05735	ENOG4105CFH	Aspartokinase
GW538_RS05745	ENOG4105D98	threonine synthase
GW538_RS05765	ENOG4105DQ6	Transposase
GW538_RS05770	ENOG4105D06	uba thif-type nad fad binding protein
GW538_RS05780	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GW538_RS05835	ENOG4105DTS	flagellar hook-associated
GW538_RS05840	ENOG4105MQ3	flagellar protein FliS
GW538_RS05880	ENOG4105CPF	Cell wall formation (By similarity)
GW538_RS05890	ENOG4108NVR	Methyl-accepting chemotaxis
GW538_RS05905	ENOG4105CMR	udp-glucose 4-epimerase
GW538_RS05915	ENOG4105D3G	Pseudouridine synthase
GW538_RS05920	ENOG4105D3W	isochorismatase
GW538_RS05925	ENOG4105CR4	methylisocitrate lyase
GW538_RS05955	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GW538_RS05960	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GW538_RS05975	ENOG4105F9F	transposase
GW538_RS05990	ENOG4105F9F	transposase
GW538_RS06000	ENOG4107B2H	carbonic anhydrase
GW538_RS06005	ENOG4105C2C	drug resistance transporter, Bcr CflA
GW538_RS06010	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GW538_RS06020	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GW538_RS06025	ENOG4108M8S	permease YjgP YjgQ family protein
GW538_RS06035	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GW538_RS06040	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GW538_RS06045	ENOG4105VIE	preprotein translocase, subunit YajC
GW538_RS06050	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GW538_RS06055	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GW538_RS06070	ENOG4105CRQ	synthase (Component I)
GW538_RS06080	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GW538_RS06090	ENOG4105ECP	epimerase
GW538_RS06120	ENOG4108SER	Transposase
GW538_RS06170	ENOG4108BUD	transposase
GW538_RS06175	ENOG4108BUD	transposase
GW538_RS06185	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GW538_RS06190	ENOG4107QMS	site-determining protein
GW538_RS06195	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GW538_RS06210	ENOG4105C8J	)-transporter
GW538_RS06215	ENOG4105CGK	Exodeoxyribonuclease III
GW538_RS06245	ENOG4108SER	Transposase
GW538_RS06260	ENOG4105C8Q	Methyl-accepting chemotaxis
GW538_RS06275	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GW538_RS06280	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GW538_RS06285	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GW538_RS06300	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GW538_RS06350	ENOG4105C2M	dna polymerase I
GW538_RS06360	ENOG4105C5H	ABC transporter
GW538_RS06375	ENOG4108SER	Transposase
GW538_RS06405	ENOG4108SER	Transposase
GW538_RS06440	ENOG4108SER	Transposase
GW538_RS06450	ENOG4105F9F	transposase
GW538_RS06485	ENOG4105E0X	reductase
GW538_RS06495	ENOG4105VMP	Transcriptional regulator
GW538_RS06510	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GW538_RS06515	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GW538_RS06525	ENOG4105C8V	SAICAR synthetase
GW538_RS06565	ENOG4105CZX	twitching motility protein
GW538_RS06665	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GW538_RS06670	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GW538_RS06675	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GW538_RS06680	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GW538_RS06685	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GW538_RS06690	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GW538_RS06710	ENOG4105CGY	Dna recombination protein
GW538_RS06715	ENOG4107SDU	Methyl-accepting chemotaxis
GW538_RS06720	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
GW538_RS06730	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
GW538_RS06735	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GW538_RS06770	ENOG4108UPT	UPF0178 protein
GW538_RS06775	ENOG4105DJ4	phosphatidylserine decarboxylase
GW538_RS06780	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GW538_RS06790	ENOG4105K8N	protein family UPF0079, ATPase
GW538_RS06795	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GW538_RS06800	ENOG4108RMU	ferritin dps family protein
GW538_RS06805	ENOG4105CH6	catalase
GW538_RS06810	ENOG41080XQ	Signal transduction protein with cbs domains
GW538_RS06840	ENOG4108SER	Transposase
GW538_RS06850	ENOG4105F9F	transposase
GW538_RS06865	ENOG4108SER	Transposase
GW538_RS06875	ENOG4105F9F	transposase
GW538_RS06885	ENOG4105C5H	ABC transporter
GW538_RS06895	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GW538_RS06905	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GW538_RS06910	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GW538_RS06915	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GW538_RS06920	ENOG4105E96	Colicin v production protein
GW538_RS06925	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GW538_RS06930	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
GW538_RS06935	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GW538_RS06950	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GW538_RS06960	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GW538_RS06965	ENOG4105Y3E	Modulates RecA activity (By similarity)
GW538_RS06970	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GW538_RS06975	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GW538_RS07010	ENOG4107QTZ	amino acid
GW538_RS07015	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GW538_RS07020	ENOG4105CXY	transporter
GW538_RS07025	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GW538_RS07030	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GW538_RS07035	ENOG4107QJR	hflk protein
GW538_RS07040	ENOG4105EPW	hflc protein
GW538_RS07045	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GW538_RS07050	ENOG4105C7N	Xanthine uracil vitamin C permease
GW538_RS07055	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GW538_RS07060	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GW538_RS07115	ENOG4108BUD	transposase
GW538_RS07120	ENOG4105E0A	ABC, transporter
GW538_RS07125	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GW538_RS07135	ENOG4105C6X	Major Facilitator
GW538_RS07145	ENOG4105CPF	Cell wall formation (By similarity)
GW538_RS07150	ENOG4105GAV	receptor
GW538_RS07155	ENOG4105M8K	biopolymer transport protein
GW538_RS07175	ENOG4108MES	Periplasmic binding protein
GW538_RS07180	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
GW538_RS07190	ENOG4108SER	Transposase
GW538_RS07205	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GW538_RS07215	ENOG4108Z4U	Ferredoxin
GW538_RS07225	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GW538_RS07230	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GW538_RS07235	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GW538_RS07290	ENOG4105F9F	transposase
GW538_RS07310	ENOG4108SER	Transposase
GW538_RS07355	ENOG4108SER	Transposase
GW538_RS07370	ENOG4105D1H	recombination factor protein RarA
GW538_RS07375	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
GW538_RS07380	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GW538_RS07385	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GW538_RS07390	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GW538_RS07400	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GW538_RS07405	ENOG4107QTZ	amino acid
GW538_RS07410	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GW538_RS07415	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GW538_RS07420	ENOG4105I03	Flagellin
GW538_RS07440	ENOG4108SER	Transposase
GW538_RS07495	ENOG4105F9F	transposase
GW538_RS07500	ENOG4105E2S	oxidase) subunit II
GW538_RS07505	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GW538_RS07510	ENOG4105CCU	oxidase (Subunit III)
GW538_RS07515	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
GW538_RS07560	ENOG4105DUX	Transporter
GW538_RS07570	ENOG4108DMH	HTH_ARAC
GW538_RS07585	ENOG4105E0U	tyrosine-specific transport protein
GW538_RS07595	ENOG4108DG9	Smr protein MutS2
GW538_RS07605	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GW538_RS07615	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GW538_RS07620	ENOG4108UYE	Lactoylglutathione lyase
GW538_RS07650	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
GW538_RS07655	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
GW538_RS07660	ENOG4105DR5	peptidase
GW538_RS07670	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GW538_RS07680	ENOG4105C5H	ABC transporter
GW538_RS07690	ENOG4105E9H	Lytic Murein transglycosylase
GW538_RS07710	ENOG4105DD5	Flagellar motor switch protein
GW538_RS07715	ENOG4105VTB	flagellar biosynthesis protein fliO
GW538_RS07720	ENOG4105CN7	Flagellar biosynthetic protein FliP
GW538_RS07725	ENOG4105VS8	Flagellar biosynthetic protein fliq
GW538_RS07730	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GW538_RS07735	ENOG4105D00	flagellar biosynthetic protein flhB
GW538_RS07740	ENOG4105D7B	Flagellar biosynthesis protein flha
GW538_RS07745	ENOG4105FZW	flagellar biosynthesis regulator FlhF
GW538_RS07755	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GW538_RS07760	ENOG4108VYJ	response regulator receiver protein
GW538_RS07765	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GW538_RS07790	ENOG4105UFH	BadM Rrf2 family transcriptional regulator
GW538_RS07800	ENOG4105C3K	feS assembly ATPase SufC
GW538_RS07805	ENOG4105JRK	feS assembly protein SufD
GW538_RS07810	ENOG4105C9B	Cysteine desulfurase
GW538_RS07815	ENOG4105V5Z	Iron-sulfur cluster assembly accessory protein
GW538_RS07830	ENOG4105F9F	transposase
GW538_RS07845	ENOG4108NVR	Methyl-accepting chemotaxis
GW538_RS07855	ENOG4105D9N	nucleoside
GW538_RS07915	ENOG4105F9F	transposase
GW538_RS07920	ENOG4105DCF	alanine dehydrogenase
GW538_RS07970	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
GW538_RS07975	ENOG4105F1J	Homogentisate 1,2-dioxygenase
GW538_RS08000	ENOG4105F9F	transposase
GW538_RS08010	ENOG410607W	Transposase
GW538_RS08025	ENOG4105C7B	Threonine dehydratase
GW538_RS08030	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GW538_RS08035	ENOG4107RZZ	dna polymerase iii epsilon subunit
GW538_RS08045	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GW538_RS08070	ENOG4108SER	Transposase
GW538_RS08080	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GW538_RS08160	ENOG4105F9F	transposase
GW538_RS08175	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GW538_RS08200	ENOG4105F9F	transposase
GW538_RS08205	ENOG4105BZG	amino acid carrier protein
GW538_RS08210	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GW538_RS08220	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GW538_RS08230	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GW538_RS08235	ENOG4105BZ1	(ABC) transporter
GW538_RS08240	ENOG4109015	Biopolymer transport protein exbD tolR
GW538_RS08255	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GW538_RS08260	ENOG4105F9F	transposase
GW538_RS08290	ENOG4108EC8	DNA internalization-related competence protein ComEC
GW538_RS08315	ENOG4105F9F	transposase
GW538_RS08320	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GW538_RS08335	ENOG4105DUM	transcriptional regulator, lysR family
GW538_RS08365	ENOG4105C1J	atp-dependent rna helicase
GW538_RS08380	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GW538_RS08400	ENOG410829K	Lysine exporter protein (Lyse ygga)
GW538_RS08415	ENOG4105D9P	serine threonine protein kinase
GW538_RS08445	ENOG4105C9M	aspartyl-trna synthetase
GW538_RS08450	ENOG4105C2C	drug resistance transporter, Bcr CflA
GW538_RS08455	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GW538_RS08460	ENOG4108UUM	single-stranded DNA-binding protein
GW538_RS08495	ENOG410607W	Transposase
GW538_RS08500	ENOG4105F9F	transposase
GW538_RS08550	ENOG4105CHH	sulfate transporter
GW538_RS08555	ENOG4105C72	UPF0176 protein
GW538_RS08565	ENOG4107SC1	transglycosylase
GW538_RS08575	ENOG4105F9F	transposase
GW538_RS08590	ENOG4105C1J	atp-dependent rna helicase
GW538_RS08645	ENOG4107Y2X	deaminase
GW538_RS08690	ENOG4108SER	Transposase
GW538_RS08695	ENOG4105E0X	reductase
GW538_RS08710	ENOG4105F9F	transposase
GW538_RS08720	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GW538_RS08725	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GW538_RS08765	ENOG4105CNG	UPF0061 protein
GW538_RS08775	ENOG4105EEQ	Na H antiporter
GW538_RS08805	ENOG4108SER	Transposase
GW538_RS08825	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GW538_RS08860	ENOG4105C8N	cysteinyl-tRNA synthetase
GW538_RS08865	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GW538_RS08870	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GW538_RS08880	ENOG4105F2Z	3-oxoadipate enol-lactonase
GW538_RS08890	ENOG4105CQ7	ATP-dependent helicase
GW538_RS08905	ENOG4105EA8	2-Nitropropane dioxygenase
GW538_RS08965	ENOG4105CS1	NAD(P)H quinone oxidoreductase
GW538_RS08975	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GW538_RS09015	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GW538_RS09040	ENOG4105BZS	acriflavin resistance protein
GW538_RS09045	ENOG410624X	efflux transporter, rnd family, mfp subunit
GW538_RS09050	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GW538_RS09060	ENOG4105CFU	surface antigen
GW538_RS09075	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GW538_RS09215	ENOG4105F9F	transposase
GW538_RS09225	ENOG4108SER	Transposase
GW538_RS09260	ENOG4105BZS	acriflavin resistance protein
GW538_RS09265	ENOG410624X	efflux transporter, rnd family, mfp subunit
GW538_RS09270	ENOG4107Q0Y	OmpA-like transmembrane domain
GW538_RS09310	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GW538_RS09315	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GW538_RS09320	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GW538_RS09325	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GW538_RS09330	ENOG4105CBX	hi0933 family
GW538_RS09335	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GW538_RS09345	ENOG4105E39	Enoyl-CoA hydratase
GW538_RS09370	ENOG4107QPN	acyl-Coa dehydrogenase
GW538_RS09375	ENOG4105CHU	acetyl-coa acetyltransferase
GW538_RS09425	ENOG4105CJN	penicillin-binding protein
GW538_RS09440	ENOG4105DWY	Agmatine deiminase
GW538_RS09455	ENOG4108JA2	transcriptioN-repair coupling factor
GW538_RS09490	ENOG4105DHP	deoxycytidine triphosphate deaminase
GW538_RS09495	ENOG4105D1F	ATP-binding protein
GW538_RS09500	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GW538_RS09515	ENOG4108SER	Transposase
GW538_RS09555	ENOG4105F9F	transposase
GW538_RS09560	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GW538_RS09590	ENOG4105C34	Pseudouridine synthase
GW538_RS09595	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GW538_RS09650	ENOG4105F9F	transposase
GW538_RS09690	ENOG4108JQ1	Dehydrogenase
GW538_RS09715	ENOG4108SER	Transposase
GW538_RS09795	ENOG4108SER	Transposase
GW538_RS09820	ENOG4105E1Q	flagellar hook-associated protein
GW538_RS09830	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GW538_RS09840	ENOG4105CGA	flagellar basal-body rod protein FlgG
GW538_RS09845	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GW538_RS09850	ENOG4105BZE	flagellar hook protein, FlgE
GW538_RS09855	ENOG4105W00	Flagellar hook capping protein
GW538_RS09860	ENOG4108ZC9	flagellar basal-body rod protein flgc
GW538_RS09885	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
GW538_RS09890	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GW538_RS09895	ENOG4108SER	Transposase
GW538_RS09905	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GW538_RS09920	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GW538_RS09930	ENOG4107QTZ	amino acid
GW538_RS09940	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GW538_RS09945	ENOG4105DHQ	Histidine kinase
GW538_RS09980	ENOG4105F9F	transposase
GW538_RS09995	ENOG4105KUZ	arsenate reductase
GW538_RS10000	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GW538_RS10005	ENOG4105CSV	Glutaminase
GW538_RS10010	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GW538_RS10015	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GW538_RS10020	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GW538_RS10040	ENOG4105C3F	Signal peptidase i
GW538_RS10050	ENOG4105EMN	RNA polymerase sigma factor
GW538_RS10055	ENOG4108IYU	L-aspartate oxidase
GW538_RS10065	ENOG4105Y75	tpr repeat protein
GW538_RS10070	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GW538_RS10150	ENOG4108PZW	LysR family Transcriptional regulator
GW538_RS10155	ENOG4105DVT	helicase
GW538_RS10195	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GW538_RS10210	ENOG4105CDU	Replicative dna helicase
GW538_RS10215	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GW538_RS10220	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GW538_RS10225	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GW538_RS10240	ENOG4105D49	3-dehydroquinate synthase
GW538_RS10245	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GW538_RS10250	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GW538_RS10260	ENOG4105CQC	Prephenate dehydratase
GW538_RS10265	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
GW538_RS10290	ENOG4105F9F	transposase
GW538_RS10325	ENOG4108SER	Transposase
GW538_RS10340	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
GW538_RS10350	ENOG4107QNK	)-transporter
GW538_RS10365	ENOG4108SER	Transposase
GW538_RS10420	ENOG4105ER2	Ompa motb domain protein
GW538_RS10425	ENOG4105E14	MotA TolQ exbB proton channel
GW538_RS10430	ENOG4105CTB	Polyprenyl synthetase
GW538_RS10435	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
GW538_RS10485	ENOG4108SER	Transposase
GW538_RS10525	ENOG4105DQ6	Transposase
GW538_RS10585	ENOG41083UI	stage II sporulation protein
GW538_RS10590	ENOG4108BUD	transposase
GW538_RS10605	ENOG4105F9F	transposase
GW538_RS10625	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GW538_RS10630	ENOG4105CIS	alcohol dehydrogenase
GW538_RS10640	ENOG4108BUD	transposase
GW538_RS10680	ENOG4105F9F	transposase
GW538_RS10695	ENOG4108BUD	transposase
GW538_RS10710	ENOG4108SER	Transposase
GW538_RS10770	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GW538_RS10790	ENOG4105D7Z	glutathione synthase
GW538_RS10795	ENOG4105CZV	ABC transporter
GW538_RS10860	ENOG4107R88	Chemotaxis protein (CheV)
GW538_RS10875	ENOG4105F9F	transposase
GW538_RS10880	ENOG4108SER	Transposase
GW538_RS10895	ENOG4106PMH	Extracellular solute-binding protein family 3
GW538_RS10900	ENOG4105EN6	Membrane
GW538_RS10915	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GW538_RS10955	ENOG4105E0F	Histidine kinase
GW538_RS10960	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GW538_RS10980	ENOG4108UHJ	MAF-like protein
GW538_RS10995	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GW538_RS11000	ENOG4105C7I	Dehydrogenase
GW538_RS11010	ENOG4105CYN	Serine protein kinase
GW538_RS11020	ENOG4105ED1	spovr family
GW538_RS11030	ENOG4108Z4T	Peptidase M50
GW538_RS11040	ENOG41072GX	Peptidase M22 Glycoprotease
GW538_RS11045	ENOG4107Q0Y	OmpA-like transmembrane domain
GW538_RS11060	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GW538_RS11070	ENOG4105EVU	fructokinase
GW538_RS11075	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
GW538_RS11085	ENOG4105CQ0	ABC transporter
GW538_RS11095	ENOG4105CEN	a g-specific adenine glycosylase
GW538_RS11100	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GW538_RS11160	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
GW538_RS11165	ENOG4105C26	Dehydrogenase
GW538_RS11170	ENOG4105F4X	arginine
GW538_RS11175	ENOG4105CB5	ATP-dependent DNA helicase recG
GW538_RS11180	ENOG4105NAU	thioesterase Superfamily protein
GW538_RS11185	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GW538_RS11190	ENOG4105DSJ	YicC domain protein
GW538_RS11195	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GW538_RS11200	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GW538_RS11205	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GW538_RS11220	ENOG4105BZU	Histidine kinase
GW538_RS11225	ENOG4105CSH	Transporter
GW538_RS11230	ENOG4105F9F	transposase
GW538_RS11240	ENOG4108SER	Transposase
GW538_RS11255	ENOG4108SER	Transposase
GW538_RS11300	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GW538_RS11305	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GW538_RS11310	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GW538_RS11325	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GW538_RS11330	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GW538_RS11335	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GW538_RS11340	ENOG4105C5H	ABC transporter
GW538_RS11375	ENOG4105F9F	transposase
GW538_RS11390	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
GW538_RS11405	ENOG4105CAT	Cytidine monophosphate kinase
GW538_RS11410	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GW538_RS11415	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GW538_RS11430	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GW538_RS11440	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GW538_RS11465	ENOG4108SER	Transposase
GW538_RS11490	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GW538_RS11495	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GW538_RS11500	ENOG4105CXT	aspartate transcarbamylase
GW538_RS11505	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GW538_RS11515	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GW538_RS11520	ENOG4105N82	Endonuclease
GW538_RS11560	ENOG4107RDB	Major Facilitator
GW538_RS11565	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GW538_RS11570	ENOG4108R3D	Electron transport complex
GW538_RS11575	ENOG4105CSM	endonuclease III
GW538_RS11620	ENOG4108MN8	Membrane
GW538_RS11625	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
GW538_RS11640	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GW538_RS11645	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
GW538_RS11680	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
GW538_RS11695	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GW538_RS11735	ENOG4105RD7	BadF BadG BcrA BcrD
GW538_RS11745	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GW538_RS11755	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GW538_RS11760	ENOG4105WH1	Two component transcriptional regulator luxr family
GW538_RS11770	ENOG4105FR1	rard protein
GW538_RS11790	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GW538_RS11795	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GW538_RS11805	ENOG4105C02	permease
GW538_RS11830	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
GW538_RS11845	ENOG4108SER	Transposase
GW538_RS11885	ENOG4108SER	Transposase
GW538_RS11915	ENOG4105C2C	drug resistance transporter, Bcr CflA
GW538_RS11920	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GW538_RS11925	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GW538_RS11930	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GW538_RS11950	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GW538_RS11955	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GW538_RS11960	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GW538_RS11965	ENOG4105C3G	gtp-binding protein
GW538_RS11970	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GW538_RS11995	ENOG4105F9F	transposase
GW538_RS12005	ENOG4108SER	Transposase
GW538_RS12030	ENOG4105DUX	Transporter
GW538_RS12040	ENOG4105DQ6	Transposase
GW538_RS12045	ENOG4105DUX	Transporter
GW538_RS12050	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GW538_RS12055	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GW538_RS12060	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GW538_RS12065	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GW538_RS12070	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GW538_RS12075	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GW538_RS12080	ENOG4108SHN	Glycosyl transferase, family 2
GW538_RS12085	ENOG4106WTF	Glycosyl transferase, family 2
GW538_RS12090	ENOG4105D16	lipopolysaccharide heptosyltransferase i
GW538_RS12095	ENOG4105XA0	heptosyltransferase ii
GW538_RS12105	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GW538_RS12110	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GW538_RS12115	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
GW538_RS12135	ENOG4105CQB	FAD linked oxidase domain protein
GW538_RS12140	ENOG4105VC4	domain protein
GW538_RS12175	ENOG4105F9F	transposase
GW538_RS12180	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GW538_RS12185	ENOG4105BZU	Histidine kinase
GW538_RS12205	ENOG4108SER	Transposase
GW538_RS12215	ENOG4105DQ6	Transposase
GW538_RS12220	ENOG4105F9F	transposase
GW538_RS12240	ENOG4105HHA	aminodeoxychorismate lyase
GW538_RS12245	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
GW538_RS12250	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GW538_RS12255	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GW538_RS12260	ENOG4105CHR	reductase
GW538_RS12265	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GW538_RS12270	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GW538_RS12275	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GW538_RS12280	ENOG4105VGS	50s ribosomal protein l32
GW538_RS12290	ENOG4105W4M	Transport-associated protein
GW538_RS12295	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
GW538_RS12315	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GW538_RS12325	ENOG4107QNR	UPF0135 protein
GW538_RS12350	ENOG4107PE3	Mammalian cell entry related domain protein
GW538_RS12355	ENOG4105CY3	ABC transporter, permease
GW538_RS12360	ENOG4105DHJ	ABC, transporter
GW538_RS12365	ENOG4105C2X	Arabinose 5-phosphate isomerase
GW538_RS12380	ENOG4108IUZ	ABC transporter
GW538_RS12385	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GW538_RS12390	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GW538_RS12395	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GW538_RS12410	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
GW538_RS12510	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
GW538_RS12515	ENOG4105DDQ	anthranilate synthase
GW538_RS12520	ENOG4105DJV	ribulose-phosphate 3-epimerase
GW538_RS12535	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GW538_RS12540	ENOG4108S0S	Nucleotidyl transferase
GW538_RS12545	ENOG4105EHM	Aminoglycoside phosphotransferase
GW538_RS12555	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GW538_RS12560	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GW538_RS12565	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GW538_RS12570	ENOG4105NWN	ApaG protein
GW538_RS12575	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GW538_RS12585	ENOG4105F9F	transposase
GW538_RS12595	ENOG4108SER	Transposase
GW538_RS12615	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GW538_RS12620	ENOG4108JU5	Magnesium and cobalt efflux protein
GW538_RS12630	ENOG4105C9A	Phoh family
GW538_RS12635	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GW538_RS12640	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GW538_RS12645	ENOG4105F9F	transposase
GW538_RS12690	ENOG4105VFU	Rna-binding protein
GW538_RS12695	ENOG4108JQ7	(ABC) transporter
GW538_RS12700	ENOG4105C3U	ABC transporter
GW538_RS12705	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GW538_RS12715	ENOG4107QRA	Extracellular solute-binding protein, family 5
GW538_RS12720	ENOG4105CFH	Aspartokinase
GW538_RS12730	ENOG4105KME	endoribonuclease L-psp
GW538_RS12745	ENOG4105CKK	Glycosyl transferase, family 2
GW538_RS12750	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GW538_RS12755	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
GW538_RS12760	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GW538_RS12765	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
GW538_RS12770	ENOG4105KME	endoribonuclease L-psp
GW538_RS12775	ENOG4108VYJ	response regulator receiver protein
GW538_RS12835	ENOG4108SER	Transposase
GW538_RS12845	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GW538_RS12855	ENOG4108JQ7	(ABC) transporter
GW538_RS12865	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GW538_RS12875	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GW538_RS12890	ENOG4108SER	Transposase
GW538_RS12905	ENOG4108J59	Extracellular solute-binding protein, family 5
GW538_RS12940	ENOG4105M2J	Glutaredoxin
GW538_RS12945	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GW538_RS12950	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GW538_RS12955	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GW538_RS12965	ENOG4105C4K	Nad synthetase
GW538_RS13030	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GW538_RS13035	ENOG4105DUX	Transporter
GW538_RS13050	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GW538_RS13245	ENOG4105CZX	twitching motility protein
GW538_RS13290	ENOG4108I0Z	Aconitate hydratase
GW538_RS13310	ENOG4105F9F	transposase
GW538_RS13320	ENOG4108SER	Transposase
GW538_RS13330	ENOG4108ZNX	Heat shock protein
GW538_RS13335	ENOG4107QTF	adenylosuccinate lyase
GW538_RS13350	ENOG4108SER	Transposase
GW538_RS13360	ENOG4105DA5	(ABC) transporter
GW538_RS13370	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GW538_RS13390	ENOG4105N14	lysine exporter protein LysE YggA
GW538_RS13395	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GW538_RS13405	ENOG4108SER	Transposase
GW538_RS13425	ENOG4108SER	Transposase
GW538_RS13435	ENOG4105K5B	UPF0225 protein
GW538_RS13450	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
GW538_RS13460	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
GW538_RS13465	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
GW538_RS13470	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
GW538_RS13490	ENOG4105CJ3	phosphate transporter
GW538_RS13495	ENOG4107IX6	phosphate transport regulator
GW538_RS13530	ENOG4108SER	Transposase
GW538_RS13555	ENOG4108IQI	permease
GW538_RS13560	ENOG4105C9Q	fumarate hydratase class II
GW538_RS13585	ENOG4108SER	Transposase
GW538_RS13595	ENOG4108SER	Transposase
GW538_RS13625	ENOG4105F9F	transposase
GW538_RS13650	ENOG4105F9F	transposase
GW538_RS13660	ENOG4105F9F	transposase
GW538_RS13760	ENOG4105CZX	twitching motility protein
GW538_RS13815	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
GW538_RS13820	ENOG4107SVH	Potassium channel protein
GW538_RS13835	ENOG4108SER	Transposase
GW538_RS13845	ENOG4105F9F	transposase
GW538_RS13850	ENOG4105CPQ	Dehydrogenase
GW538_RS13855	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GW538_RS13890	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GW538_RS13905	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GW538_RS13915	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GW538_RS13920	ENOG4105MJ2	Competence protein
GW538_RS13945	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GW538_RS13950	ENOG4105D4A	Cell wall formation (By similarity)
GW538_RS13975	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GW538_RS13985	ENOG410607W	Transposase
GW538_RS13990	ENOG4105TRI	Hydrolase
GW538_RS13995	ENOG4108BUD	transposase
GW538_RS14000	ENOG4108SER	Transposase
GW538_RS14025	ENOG4105C8Y	Acetylornithine aminotransferase
GW538_RS14030	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GW538_RS14035	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GW538_RS14050	ENOG410842T	Pterin carbinolamine dehydratase
GW538_RS14055	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GW538_RS14060	ENOG4108VYJ	response regulator receiver protein
GW538_RS14075	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GW538_RS14080	ENOG4105D0A	hydroxylase
GW538_RS14085	ENOG4105E07	UPF0149 protein
GW538_RS14095	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GW538_RS14105	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GW538_RS14115	ENOG4108NVR	Methyl-accepting chemotaxis
GW538_RS14120	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GW538_RS14125	ENOG4107RK2	ADP-ribose diphosphatase NudE
GW538_RS14130	ENOG4105VEJ	Heat shock protein
GW538_RS14155	ENOG4105F9F	transposase
GW538_RS14180	ENOG4108SER	Transposase
GW538_RS14190	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GW538_RS14195	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GW538_RS14200	ENOG4105F0I	Aminotransferase
GW538_RS14205	ENOG4105DZ1	carboxypeptidase
GW538_RS14215	ENOG4105CVE	Lytic murein transglycosylase
GW538_RS14220	ENOG4105CNI	cell division protein FtsW
GW538_RS14225	ENOG4105CJN	penicillin-binding protein
GW538_RS14230	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GW538_RS14240	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GW538_RS14245	ENOG4105DJF	DNA polymerase III, delta' subunit
GW538_RS14255	ENOG4105C8T	Leucyl-tRNA synthetase
GW538_RS14270	ENOG4105C8Q	Methyl-accepting chemotaxis
GW538_RS14275	ENOG4105K59	histidine triad (HIT) protein
GW538_RS14280	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GW538_RS14290	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GW538_RS14300	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GW538_RS14315	ENOG4105C75	arginyL-tRNA synthetase
GW538_RS14320	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GW538_RS14340	ENOG4105C31	Tryptophanyl-tRNA synthetase
GW538_RS14345	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GW538_RS14350	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GW538_RS14385	ENOG4108SER	Transposase
GW538_RS14410	ENOG4105E66	phosphoriboisomerase A
GW538_RS14415	ENOG4105C2C	drug resistance transporter, Bcr CflA
GW538_RS14420	ENOG4108ZT0	50S ribosomal protein l17
GW538_RS14425	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GW538_RS14430	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GW538_RS14435	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GW538_RS14440	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GW538_RS14450	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GW538_RS14455	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GW538_RS14465	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GW538_RS14470	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GW538_RS14475	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GW538_RS14480	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GW538_RS14485	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GW538_RS14490	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GW538_RS14495	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GW538_RS14500	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GW538_RS14505	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GW538_RS14510	ENOG41083MP	50s ribosomal protein l29
GW538_RS14515	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GW538_RS14520	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GW538_RS14525	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GW538_RS14530	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GW538_RS14535	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GW538_RS14545	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GW538_RS14550	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GW538_RS14555	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GW538_RS14560	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GW538_RS14565	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GW538_RS14570	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GW538_RS14575	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GW538_RS14585	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GW538_RS14590	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GW538_RS14595	ENOG4108VZM	50s ribosomal protein L10
GW538_RS14600	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GW538_RS14605	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GW538_RS14610	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GW538_RS14615	ENOG4105PM1	preprotein translocase subunit SecE
GW538_RS14645	ENOG4107QHF	type ii secretion system protein e
GW538_RS14650	ENOG4105D7Q	type ii secretion system
GW538_RS14665	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GW538_RS14670	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GW538_RS14675	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GW538_RS14680	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
GW538_RS14690	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
GW538_RS14695	ENOG4105C54	Major Facilitator superfamily
GW538_RS14700	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GW538_RS14705	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GW538_RS14710	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GW538_RS14715	ENOG4105CFG	Acts as a chaperone (By similarity)
GW538_RS14720	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GW538_RS14725	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GW538_RS14730	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GW538_RS14740	ENOG41090R7	Ferric uptake
GW538_RS14755	ENOG4105VDB	UPF0125 protein
GW538_RS14760	ENOG4108Z1B	Cyclase dehydrase
GW538_RS14765	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GW538_RS14770	ENOG4105EEI	dihydropteroate synthase
GW538_RS14780	ENOG4105CSV	Glutaminase
GW538_RS14790	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GW538_RS14805	ENOG410903C	(LipO)protein
GW538_RS14815	ENOG4105F9F	transposase
GW538_RS14840	ENOG4105F9F	transposase
GW538_RS14850	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
GW538_RS14875	ENOG4105BZ4	penicillin-binding protein
GW538_RS14880	ENOG4105DJ0	Poly(A) Polymerase
GW538_RS14885	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GW538_RS14890	ENOG4105CHU	acetyl-coa acetyltransferase
GW538_RS14895	ENOG4105CHR	reductase
GW538_RS14925	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GW538_RS14930	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GW538_RS14935	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GW538_RS14940	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GW538_RS14945	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GW538_RS14950	ENOG4105CHV	Transcription elongation factor NusA
GW538_RS14965	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GW538_RS14970	ENOG4105C8S	subunit m
GW538_RS14980	ENOG41080FQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GW538_RS14985	ENOG4105DF2	NADH dehydrogenase subunit j
GW538_RS14990	ENOG41081XG	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GW538_RS14995	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GW538_RS15000	ENOG4108IEH	NADH dehydrogenase subunit g
GW538_RS15000	ENOG4108IEH	NADH dehydrogenase subunit g
GW538_RS15005	ENOG4107QIZ	NADH dehydrogenase
GW538_RS15015	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GW538_RS15025	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GW538_RS15030	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GW538_RS15045	ENOG4105CP7	Triose-phosphate isomerase
GW538_RS15060	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GW538_RS15065	ENOG4107104	thymidine kinase
GW538_RS15080	ENOG4105M08	Membrane
GW538_RS15095	ENOG4105M6F	mutator MutT protein
GW538_RS15115	ENOG4107XNQ	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GW538_RS15120	ENOG4106KNT	transcriptional regulator
GW538_RS15125	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GW538_RS15150	ENOG4105F9F	transposase
GW538_RS15165	ENOG4105MIR	Phenylalanine 4-monooxygenase
GW538_RS15170	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GW538_RS15180	ENOG4108RXX	maleylacetoacetate isomerase
GW538_RS15185	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GW538_RS15200	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GW538_RS15205	ENOG4105CGK	Exodeoxyribonuclease III
GW538_RS15210	ENOG4107QX8	SPFH domain, Band 7 family protein
GW538_RS15215	ENOG4105G5H	Membrane
GW538_RS15240	ENOG4108SER	Transposase
GW538_RS15250	ENOG4107QKV	phosphomannomutase
GW538_RS15265	ENOG4105KDC	50s ribosomal protein l28
GW538_RS15270	ENOG4105W0E	50S ribosomal protein L33
GW538_RS15290	ENOG4105CI3	gtp-binding protein typa
GW538_RS15390	ENOG4105C5I	Dehydrogenase
GW538_RS15400	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GW538_RS15405	ENOG4105K63	Thioredoxin
GW538_RS15410	ENOG4105C9X	ppx gppa phosphatase
GW538_RS15420	ENOG4105D52	delta-aminolevulinic acid dehydratase
GW538_RS15425	ENOG4107QTZ	amino acid
GW538_RS15430	ENOG4105C5F	glutamine synthetase
GW538_RS15475	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GW538_RS15485	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
GW538_RS15510	ENOG4105F9F	transposase
GW538_RS15530	ENOG4105E5M	Multidrug resistance protein D
GW538_RS15535	ENOG4105EJC	lysr family transcriptional regulator
GW538_RS15545	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GW538_RS15550	ENOG4105E4G	Type IV pilus
GW538_RS15555	ENOG4105E4G	Type IV pilus
GW538_RS15580	ENOG4108JQC	penicillin-binding protein 1A
GW538_RS15600	ENOG4105N82	Endonuclease
GW538_RS15605	ENOG4105C5S	asparaginyl-tRNA synthetase
GW538_RS15695	ENOG4105C0P	Mg chelatase subunit ChlI
GW538_RS15705	ENOG4108YZA	Nitrogen regulatory protein pii
GW538_RS15710	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GW538_RS15720	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
GW538_RS15725	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
GW538_RS15735	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GW538_RS15750	ENOG4107RI6	Anthranilate phosphoribosyltransferase
GW538_RS15755	ENOG4105DDQ	anthranilate synthase
GW538_RS15790	ENOG4105D3R	alkyl hydroperoxide reductase
GW538_RS15815	ENOG4105F9F	transposase
GW538_RS15825	ENOG4108SER	Transposase
GW538_RS15830	ENOG4108SER	Transposase
GW538_RS15870	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
GW538_RS15875	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GW538_RS15880	ENOG4108S4H	thioesterase Superfamily protein
GW538_RS15885	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GW538_RS15910	ENOG4105C7F	AcnD-accessory protein PrpF
GW538_RS15915	ENOG41080IJ	Diacylglycerol kinase
GW538_RS15920	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GW538_RS15925	ENOG4105C1A	potassium transporter peripheral membrane
GW538_RS15930	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GW538_RS15935	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GW538_RS15940	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GW538_RS15945	ENOG4105C79	DNA protecting protein DprA
GW538_RS15950	ENOG4108RPN	Protein smg homolog
GW538_RS15960	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GW538_RS15965	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GW538_RS15975	ENOG4105F9F	transposase
GW538_RS15990	ENOG4105F9F	transposase
GW538_RS16010	ENOG4108SER	Transposase
GW538_RS16035	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GW538_RS16045	ENOG4105CN1	protease
GW538_RS16055	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GW538_RS16065	ENOG4108SER	Transposase
GW538_RS16080	ENOG4105C5W	Aldolase
GW538_RS16090	ENOG4105C2M	dna polymerase I
GW538_RS16095	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
GW538_RS16105	ENOG4105D4Y	metalloprotease
GW538_RS16120	ENOG4105RHY	Pfam:UPF0157
GW538_RS16145	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
GW538_RS16155	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GW538_RS16160	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GW538_RS16165	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GW538_RS16170	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GW538_RS16175	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GW538_RS16180	ENOG4105CPF	Cell wall formation (By similarity)
GW538_RS16185	ENOG4105DFU	Cell wall formation (By similarity)
GW538_RS16190	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GW538_RS16195	ENOG4105CNI	cell division protein FtsW
GW538_RS16200	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GW538_RS16205	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GW538_RS16210	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GW538_RS16215	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GW538_RS16220	ENOG4105CJN	penicillin-binding protein
GW538_RS16230	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GW538_RS16235	ENOG4108ZZ3	UPF0260 protein
GW538_RS16250	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GW538_RS16255	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GW538_RS16260	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GW538_RS16265	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GW538_RS16300	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GW538_RS16305	ENOG4105DQ4	alcohol dehydrogenase
GW538_RS16330	ENOG4105XMH	SpoVT AbrB domain protein
GW538_RS16360	ENOG4105CAR	Terminase, large subunit
GW538_RS16365	ENOG4105CAR	Terminase, large subunit
GW538_RS16375	ENOG4108BUD	transposase
GW538_RS16405	ENOG4108BUD	transposase
GW538_RS16410	ENOG4105F9F	transposase
GW538_RS16535	ENOG4108BUD	transposase
GW538_RS16580	ENOG4108BUD	transposase
GW538_RS16615	ENOG4108BUD	transposase
GW538_RS16625	ENOG4108BUD	transposase
GW538_RS16675	ENOG4108BUD	transposase
GW538_RS16695	ENOG4108BUD	transposase
GW538_RS16705	ENOG4105C0D	helicase
GW538_RS16710	ENOG4108BUD	transposase
GW538_RS16715	ENOG4105F9F	transposase
GW538_RS16720	ENOG4108BUD	transposase
GW538_RS16725	ENOG4108BUD	transposase
GW538_RS16740	ENOG4108BUD	transposase
GW538_RS16760	ENOG4107QJE	Chromosome Partitioning Protein
GW538_RS16770	ENOG4105F9F	transposase
GW538_RS16845	ENOG4108SER	Transposase
GW538_RS16855	ENOG4108BUD	transposase
GW538_RS16865	ENOG4105F9F	transposase
GW538_RS16905	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
GW538_RS16910	ENOG4108BUD	transposase
GW538_RS16920	ENOG4108BUD	transposase
GW538_RS16935	ENOG4108BUD	transposase
GW538_RS16955	ENOG4108BUD	transposase
GW538_RS17010	ENOG4108BUD	transposase
GW538_RS17015	ENOG4108MP6	LysR family Transcriptional regulator
GW538_RS17025	ENOG4105HF0	Membrane
GW538_RS17030	ENOG4105F9F	transposase
GW538_RS17045	ENOG4108BUD	transposase
GW538_RS17055	ENOG4108BUD	transposase
GW538_RS17075	ENOG4108SER	Transposase
GW538_RS17090	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GW538_RS17115	ENOG4108BUD	transposase
GW538_RS17125	ENOG4108BUD	transposase
GW538_RS17175	ENOG4108BUD	transposase
GW538_RS17180	ENOG4105E3A	(ABC) transporter
GW538_RS17230	ENOG4108BUD	transposase
GW538_RS17250	ENOG4108BUD	transposase
GW538_RS17270	ENOG4108BUD	transposase
GW538_RS17315	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
GW538_RS17320	ENOG4108BUD	transposase
GW538_RS17325	ENOG410607W	Transposase
GW538_RS17370	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
GW538_RS17375	ENOG4108BUD	transposase
GW538_RS17385	ENOG410607W	Transposase
GW538_RS17425	ENOG41062D9	Histidine kinase
GW538_RS17435	ENOG4105ESI	atpase involved in dna repair
GW538_RS17445	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GW538_RS17450	ENOG4105DQ4	alcohol dehydrogenase
GW538_RS17475	ENOG4105XMH	SpoVT AbrB domain protein
GW538_RS17480	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
GW538_RS17515	ENOG4105CAR	Terminase, large subunit
GW538_RS17525	ENOG4108BUD	transposase
GW538_RS17595	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GW538_RS17650	ENOG4105F9F	transposase
GW538_RS17675	ENOG4105F9F	transposase
GW538_RS17685	ENOG4105F9F	transposase
GW538_RS17695	ENOG4108ISG	Major Facilitator
GW538_RS17715	ENOG4105F9F	transposase
GW538_RS17725	ENOG4105VUH	addiction module killer protein
GW538_RS17765	ENOG410607W	Transposase
GW538_RS17775	ENOG4105F9F	transposase
GW538_RS17795	ENOG4105F9F	transposase
GW538_RS17815	ENOG4105F9F	transposase
GW538_RS17915	ENOG4108Q9H	CobQ/CobB/MinD/ParA nucleotide binding domain
GW538_RS17940	ENOG4105F9F	transposase
GW538_RS17965	ENOG4105F9F	transposase
GW538_RS17975	ENOG4105F9F	transposase
GW538_RS17985	ENOG4108ISG	Major Facilitator
GW538_RS18045	ENOG4105F9F	transposase
GW538_RS18060	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GW538_RS18070	ENOG4105F9F	transposase
GW538_RS18085	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
GW538_RS18090	ENOG4107QJE	Chromosome Partitioning Protein
GW538_RS18120	ENOG4105F9F	transposase
GW538_RS18140	ENOG4105F9F	transposase
GW538_RS18160	ENOG4105F9F	transposase
GW538_RS18205	ENOG4105F9F	transposase
GW538_RS18220	ENOG4105F9F	transposase
GW538_RS18245	ENOG4105F9F	transposase
GW538_RS18270	ENOG4105F9F	transposase
GW538_RS18285	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GW538_RS18295	ENOG4105F9F	transposase
GW538_RS18310	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
GW538_RS18315	ENOG4107QJE	Chromosome Partitioning Protein
GW538_RS18375	ENOG4105F9F	transposase