locus-tag	class	description
ICC15_RS00015	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ICC15_RS00055	COG4221	oxidoreductase activity
ICC15_RS00065	COG3676	manually curated
ICC15_RS00090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICC15_RS00100	COG0281	malic enzyme
ICC15_RS00105	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ICC15_RS00110	COG0814	amino acid
ICC15_RS00150	COG1678	Uncharacterized ACR, COG1678
ICC15_RS00170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ICC15_RS00185	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ICC15_RS00190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ICC15_RS00195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ICC15_RS00200	COG0189	ligase activity
ICC15_RS00210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICC15_RS00255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ICC15_RS00265	COG0793	Belongs to the peptidase S41A family
ICC15_RS00275	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICC15_RS00290	COG3335	DDE superfamily endonuclease
ICC15_RS00310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICC15_RS00310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICC15_RS00320	COG3335	DDE superfamily endonuclease
ICC15_RS00345	COG3227	Zinc metalloprotease (Elastase)
ICC15_RS00360	COG0456	acetyltransferase
ICC15_RS00360	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ICC15_RS00390	COG0653	protein targeting
ICC15_RS00395	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ICC15_RS00400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ICC15_RS00410	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ICC15_RS00420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ICC15_RS00425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ICC15_RS00430	COG0772	Belongs to the SEDS family
ICC15_RS00435	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICC15_RS00440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICC15_RS00445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ICC15_RS00450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICC15_RS00465	COG0275	rRNA processing
ICC15_RS00470	COG2983	Belongs to the UPF0260 family
ICC15_RS00490	COG0187	DNA topoisomerase II activity
ICC15_RS00500	COG0592	DNA-directed DNA polymerase activity
ICC15_RS00505	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICC15_RS00510	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ICC15_RS00515	COG0594	ribonuclease P activity
ICC15_RS00520	COG0706	membrane insertase activity
ICC15_RS00525	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ICC15_RS00540	COG1192	Involved in chromosome partitioning
ICC15_RS00545	COG1475	DNA binding
ICC15_RS00555	COG0356	it plays a direct role in the translocation of protons across the membrane
ICC15_RS00565	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ICC15_RS00570	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICC15_RS00575	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ICC15_RS00580	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ICC15_RS00585	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ICC15_RS00595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICC15_RS00600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ICC15_RS00625	COG3344	reverse transcriptase
ICC15_RS00655	COG0489	protein tyrosine kinase activity
ICC15_RS00685	COG2226	methyltransferase
ICC15_RS00685	COG2867	negative regulation of translational initiation
ICC15_RS00690	COG3676	manually curated
ICC15_RS00695	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS00700	COG2814	Major facilitator Superfamily
ICC15_RS00720	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ICC15_RS00725	COG0109	protoheme IX farnesyltransferase activity
ICC15_RS00740	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS00770	COG3335	DDE superfamily endonuclease
ICC15_RS00810	COG4221	oxidoreductase activity
ICC15_RS00840	COG0408	coproporphyrinogen oxidase activity
ICC15_RS00845	COG0009	L-threonylcarbamoyladenylate synthase
ICC15_RS00855	COG2922	Belongs to the Smg family
ICC15_RS00860	COG0758	DNA mediated transformation
ICC15_RS00865	COG0242	peptide deformylase activity
ICC15_RS00875	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICC15_RS00880	COG0569	domain protein
ICC15_RS00885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ICC15_RS00890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ICC15_RS00895	COG2828	Protein conserved in bacteria
ICC15_RS00920	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ICC15_RS00925	COG1607	acyl-coa hydrolase
ICC15_RS00935	COG0752	glycyl-tRNA synthetase alpha subunit
ICC15_RS00995	COG0450	alkyl hydroperoxide reductase
ICC15_RS01015	COG3335	DDE superfamily endonuclease
ICC15_RS01030	COG0697	spore germination
ICC15_RS01045	COG0512	Glutamine amidotransferase of anthranilate synthase
ICC15_RS01045	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ICC15_RS01050	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ICC15_RS01055	COG0134	indole-3-glycerol-phosphate synthase activity
ICC15_RS01060	COG0135	phosphoribosylanthranilate isomerase activity
ICC15_RS01065	COG0133	tryptophan synthase activity
ICC15_RS01075	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ICC15_RS01090	COG1166	arginine decarboxylase activity
ICC15_RS01095	COG0347	Belongs to the P(II) protein family
ICC15_RS01105	COG0606	chelatase, subunit chli
ICC15_RS01110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICC15_RS01115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICC15_RS01130	COG3451	type IV secretory pathway VirB4
ICC15_RS01140	COG3504	Conjugal transfer protein
ICC15_RS01145	COG2948	multi-organism process
ICC15_RS01165	COG4962	Type ii secretion system protein e
ICC15_RS01170	COG0017	Asparaginyl-tRNA synthetase
ICC15_RS01215	COG3335	DDE superfamily endonuclease
ICC15_RS01245	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ICC15_RS01255	COG0583	DNA-binding transcription factor activity
ICC15_RS01260	COG2814	Major facilitator Superfamily
ICC15_RS01265	COG2271	Major facilitator Superfamily
ICC15_RS01305	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS01320	COG2988	succinylglutamate desuccinylase activity
ICC15_RS01345	COG0668	transmembrane transport
ICC15_RS01350	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICC15_RS01355	COG0174	glutamine synthetase
ICC15_RS01360	COG0531	amino acid
ICC15_RS01390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICC15_RS01445	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ICC15_RS01470	COG1217	gtp-binding protein TYPA
ICC15_RS01490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ICC15_RS01495	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ICC15_RS01500	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ICC15_RS01515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICC15_RS01530	COG0837	glucose binding
ICC15_RS01530	COG1737	Transcriptional regulator
ICC15_RS01545	COG0254	rRNA binding
ICC15_RS01550	COG0281	malic enzyme
ICC15_RS01600	COG0625	glutathione transferase activity
ICC15_RS01605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICC15_RS01620	COG3335	DDE superfamily endonuclease
ICC15_RS01625	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ICC15_RS01630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICC15_RS01630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ICC15_RS01635	COG0708	Exodeoxyribonuclease III
ICC15_RS01640	COG0330	HflC and HflK could
ICC15_RS01645	COG1585	Membrane protein implicated in regulation of membrane protease activity
ICC15_RS01665	COG0494	nUDIX hydrolase
ICC15_RS01680	COG2363	Small membrane protein
ICC15_RS01685	COG1435	thymidine kinase activity
ICC15_RS01695	COG3023	N-Acetylmuramoyl-L-alanine amidase
ICC15_RS01705	COG0149	triose-phosphate isomerase activity
ICC15_RS01710	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ICC15_RS01720	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICC15_RS01725	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICC15_RS01735	COG0649	NAD binding
ICC15_RS01740	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ICC15_RS01745	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ICC15_RS01750	COG1034	ATP synthesis coupled electron transport
ICC15_RS01755	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ICC15_RS01760	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICC15_RS01765	COG0839	Belongs to the complex I subunit 6 family
ICC15_RS01770	COG0713	ATP synthesis coupled electron transport
ICC15_RS01785	COG1007	ATP synthesis coupled electron transport
ICC15_RS01800	COG0195	Participates in both transcription termination and antitermination
ICC15_RS01800	COG2251	uridine kinase activity
ICC15_RS01805	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ICC15_RS01810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ICC15_RS01815	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ICC15_RS01820	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ICC15_RS01825	COG1185	polyribonucleotide nucleotidyltransferase activity
ICC15_RS01835	COG3243	poly(R)-hydroxyalkanoic acid synthase
ICC15_RS01855	COG1028	Short-chain dehydrogenase reductase Sdr
ICC15_RS01865	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ICC15_RS01870	COG0617	tRNA 3'-terminal CCA addition
ICC15_RS01875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ICC15_RS01895	COG1028	Short-chain dehydrogenase reductase Sdr
ICC15_RS01900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICC15_RS01905	COG1028	Short-chain dehydrogenase reductase Sdr
ICC15_RS01930	COG2853	Lipoprotein
ICC15_RS01945	COG1490	D-aminoacyl-tRNA deacylase activity
ICC15_RS01950	COG0596	Alpha beta hydrolase
ICC15_RS01955	COG2066	Belongs to the glutaminase family
ICC15_RS01970	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ICC15_RS01975	COG2867	negative regulation of translational initiation
ICC15_RS01980	COG2914	Belongs to the UPF0125 (RnfH) family
ICC15_RS01995	COG0735	belongs to the Fur family
ICC15_RS02015	COG0497	DNA recombination
ICC15_RS02020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ICC15_RS02025	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ICC15_RS02030	COG0443	Heat shock 70 kDa protein
ICC15_RS02035	COG0484	heat shock protein binding
ICC15_RS02050	COG0477	Major facilitator Superfamily
ICC15_RS02055	COG3130	regulation of translation
ICC15_RS02065	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ICC15_RS02070	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ICC15_RS02085	COG1459	type II secretion system
ICC15_RS02090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICC15_RS02095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICC15_RS02125	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ICC15_RS02135	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ICC15_RS02140	COG0081	regulation of translation
ICC15_RS02145	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ICC15_RS02150	COG0222	ribosome binding
ICC15_RS02155	COG0085	RNA polymerase activity
ICC15_RS02165	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ICC15_RS02170	COG0049	tRNA binding
ICC15_RS02175	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICC15_RS02180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICC15_RS02185	COG0051	transcription antitermination factor activity, RNA binding
ICC15_RS02190	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ICC15_RS02195	COG0088	Forms part of the polypeptide exit tunnel
ICC15_RS02200	COG0089	rRNA binding
ICC15_RS02205	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ICC15_RS02210	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ICC15_RS02215	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ICC15_RS02220	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ICC15_RS02225	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ICC15_RS02230	COG0255	Belongs to the universal ribosomal protein uL29 family
ICC15_RS02235	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ICC15_RS02245	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ICC15_RS02255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICC15_RS02260	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ICC15_RS02265	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ICC15_RS02270	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ICC15_RS02275	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ICC15_RS02285	COG0200	Binds to the 23S rRNA
ICC15_RS02300	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ICC15_RS02305	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ICC15_RS02310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ICC15_RS02315	COG0202	RNA polymerase activity
ICC15_RS02320	COG0203	ribosomal protein L17
ICC15_RS02325	COG2814	Major facilitator Superfamily
ICC15_RS02330	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ICC15_RS02360	COG3335	DDE superfamily endonuclease
ICC15_RS02450	COG1253	flavin adenine dinucleotide binding
ICC15_RS02460	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS02465	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ICC15_RS02470	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ICC15_RS02475	COG0180	Tryptophanyl-tRNA synthetase
ICC15_RS02480	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS02515	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ICC15_RS02520	COG0018	arginyl-trna synthetase
ICC15_RS02535	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ICC15_RS02545	COG2226	methyltransferase
ICC15_RS02555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ICC15_RS02580	COG3293	Transposase
ICC15_RS02590	COG0495	leucyl-tRNA aminoacylation
ICC15_RS02600	COG1466	dna polymerase III delta subunit
ICC15_RS02615	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ICC15_RS02620	COG0768	penicillin binding
ICC15_RS02625	COG0772	Belongs to the SEDS family
ICC15_RS02630	COG2951	lytic endotransglycosylase activity
ICC15_RS02640	COG1686	Belongs to the peptidase S11 family
ICC15_RS02650	COG0321	lipoyl(octanoyl) transferase activity
ICC15_RS02655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ICC15_RS02720	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ICC15_RS02725	COG0494	nUDIX hydrolase
ICC15_RS02745	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICC15_RS02765	COG3079	Belongs to the UPF0149 family
ICC15_RS02770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICC15_RS02775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICC15_RS02790	COG0745	RESPONSE REGULATOR receiver
ICC15_RS02795	COG0776	regulation of translation
ICC15_RS02815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICC15_RS02825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ICC15_RS02840	COG3335	DDE superfamily endonuclease
ICC15_RS02850	COG3483	tryptophan 2,3-dioxygenase activity
ICC15_RS02870	COG0728	peptidoglycan biosynthetic process
ICC15_RS02875	COG0196	riboflavin kinase activity
ICC15_RS02880	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ICC15_RS02885	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ICC15_RS02890	COG1047	Peptidyl-prolyl cis-trans
ICC15_RS02910	COG2271	Major facilitator Superfamily
ICC15_RS02920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ICC15_RS02935	COG0840	transmembrane signaling receptor activity
ICC15_RS02970	COG1051	belongs to the nudix hydrolase family
ICC15_RS02985	COG0735	belongs to the Fur family
ICC15_RS02990	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ICC15_RS03000	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ICC15_RS03005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ICC15_RS03010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ICC15_RS03015	COG0126	phosphoglycerate kinase activity
ICC15_RS03050	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS03065	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ICC15_RS03100	COG0784	Response regulator, receiver
ICC15_RS03100	COG0835	chemotaxis
ICC15_RS03115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICC15_RS03120	COG2814	Major facilitator Superfamily
ICC15_RS03130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ICC15_RS03135	COG3293	Transposase
ICC15_RS03185	COG0307	riboflavin synthase, alpha
ICC15_RS03190	COG0189	ligase activity
ICC15_RS03245	COG1392	Phosphate transport regulator
ICC15_RS03250	COG0306	phosphate transporter
ICC15_RS03265	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ICC15_RS03270	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ICC15_RS03275	COG0235	Class ii aldolase
ICC15_RS03280	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ICC15_RS03295	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ICC15_RS03310	COG3012	SEC-C Motif Domain Protein
ICC15_RS03320	COG3335	DDE superfamily endonuclease
ICC15_RS03365	COG0205	6-phosphofructokinase activity
ICC15_RS03375	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ICC15_RS03405	COG0546	phosphoglycolate phosphatase activity
ICC15_RS03410	COG3139	Protein of unknown function (DUF1315)
ICC15_RS03420	COG2350	Protein conserved in bacteria
ICC15_RS03425	COG2917	probably involved in intracellular septation
ICC15_RS03430	COG0009	L-threonylcarbamoyladenylate synthase
ICC15_RS03440	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ICC15_RS03465	COG0739	heme binding
ICC15_RS03470	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ICC15_RS03480	COG0670	Belongs to the BI1 family
ICC15_RS03485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICC15_RS03500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICC15_RS03595	COG2801	Transposase and inactivated derivatives
ICC15_RS03650	COG3177	Filamentation induced by cAMP protein fic
ICC15_RS03665	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ICC15_RS03700	COG1192	Involved in chromosome partitioning
ICC15_RS03725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ICC15_RS03760	COG1192	Involved in chromosome partitioning
ICC15_RS03785	COG2801	Transposase and inactivated derivatives
ICC15_RS03815	COG1028	Short-chain dehydrogenase reductase Sdr
ICC15_RS03830	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ICC15_RS03835	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ICC15_RS03835	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ICC15_RS03850	COG0783	Belongs to the Dps family
ICC15_RS03860	COG1040	competence protein
ICC15_RS03865	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ICC15_RS03875	COG0596	Alpha beta hydrolase
ICC15_RS03890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICC15_RS03930	COG1063	alcohol dehydrogenase
ICC15_RS03935	COG0156	8-amino-7-oxononanoate synthase activity
ICC15_RS03985	COG0166	Belongs to the GPI family
ICC15_RS03995	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ICC15_RS04035	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ICC15_RS04100	COG0742	ribosomal rna small subunit methyltransferase
ICC15_RS04105	COG1760	l-serine dehydratase
ICC15_RS04135	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ICC15_RS04140	COG0471	metal ion transport
ICC15_RS04140	COG3273	potassium ion transport
ICC15_RS04165	COG4206	TonB-dependent receptor
ICC15_RS04175	COG1131	(ABC) transporter
ICC15_RS04185	COG2963	transposase activity
ICC15_RS04190	COG2801	Transposase and inactivated derivatives
ICC15_RS04205	COG0517	IMP dehydrogenase activity
ICC15_RS04205	COG0516	GMP reductase activity
ICC15_RS04210	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ICC15_RS04215	COG0071	Belongs to the small heat shock protein (HSP20) family
ICC15_RS04245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ICC15_RS04290	COG2805	Type II/IV secretion system protein
ICC15_RS04385	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS04395	COG0477	Major facilitator Superfamily
ICC15_RS04405	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS04485	COG0425	Belongs to the sulfur carrier protein TusA family
ICC15_RS04495	COG0835	chemotaxis
ICC15_RS04495	COG0784	Response regulator, receiver
ICC15_RS04505	COG0242	peptide deformylase activity
ICC15_RS04525	COG2217	Heavy metal translocating P-type atpase
ICC15_RS04550	COG3335	DDE superfamily endonuclease
ICC15_RS04570	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ICC15_RS04570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICC15_RS04580	COG0167	dihydroorotate dehydrogenase activity
ICC15_RS04590	COG0813	purine-nucleoside phosphorylase activity
ICC15_RS04595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ICC15_RS04625	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ICC15_RS04635	COG1619	proteins homologs of microcin C7 resistance protein MccF
ICC15_RS04650	COG2076	Multidrug Resistance protein
ICC15_RS04655	COG0628	permease
ICC15_RS04665	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ICC15_RS04670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICC15_RS04695	COG2962	Rard protein
ICC15_RS04700	COG2197	response regulator
ICC15_RS04715	COG1959	2 iron, 2 sulfur cluster binding
ICC15_RS04720	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ICC15_RS04725	COG2814	Major facilitator Superfamily
ICC15_RS04730	COG2971	BadF BadG BcrA BcrD
ICC15_RS04755	COG0617	tRNA 3'-terminal CCA addition
ICC15_RS04765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ICC15_RS04770	COG1702	phosphate starvation-inducible protein PhoH
ICC15_RS04775	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ICC15_RS04780	COG4535	Mg2 and Co2 transporter CorC
ICC15_RS04785	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ICC15_RS04795	COG2963	transposase activity
ICC15_RS04800	COG2801	Transposase and inactivated derivatives
ICC15_RS04810	COG3335	DDE superfamily endonuclease
ICC15_RS04825	COG3335	DDE superfamily endonuclease
ICC15_RS04845	COG3335	DDE superfamily endonuclease
ICC15_RS04860	COG0601	transmembrane transport
ICC15_RS04865	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS04870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICC15_RS04890	COG0328	RNA-DNA hybrid ribonuclease activity
ICC15_RS04965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICC15_RS04970	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICC15_RS04975	COG2076	Multidrug Resistance protein
ICC15_RS04980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ICC15_RS04985	COG0463	Glycosyl transferase, family 2
ICC15_RS04990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ICC15_RS04990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICC15_RS05005	COG0019	diaminopimelate decarboxylase activity
ICC15_RS05010	COG0527	aspartate kinase activity
ICC15_RS05015	COG0747	negative chemotaxis
ICC15_RS05020	COG0601	transmembrane transport
ICC15_RS05025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICC15_RS05035	COG4608	Belongs to the ABC transporter superfamily
ICC15_RS05040	COG0724	RNA recognition motif
ICC15_RS05045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ICC15_RS05085	COG0742	ribosomal rna small subunit methyltransferase
ICC15_RS05120	COG2095	MarC family integral membrane protein
ICC15_RS05125	COG2920	part of a sulfur-relay system
ICC15_RS05135	COG2923	Belongs to the DsrF TusC family
ICC15_RS05140	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ICC15_RS05145	COG0670	Belongs to the BI1 family
ICC15_RS05170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ICC15_RS05175	COG2878	Part of a membrane complex involved in electron transport
ICC15_RS05190	COG2814	Major facilitator Superfamily
ICC15_RS05230	COG0295	cytidine deaminase activity
ICC15_RS05240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICC15_RS05245	COG0542	response to heat
ICC15_RS05255	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ICC15_RS05260	COG0540	Belongs to the ATCase OTCase family
ICC15_RS05265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ICC15_RS05270	COG0505	Belongs to the CarA family
ICC15_RS05305	COG3335	DDE superfamily endonuclease
ICC15_RS05315	COG0798	PFAM Bile acid sodium symporter
ICC15_RS05350	COG0402	S-adenosylhomocysteine deaminase activity
ICC15_RS05355	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS05375	COG3335	DDE superfamily endonuclease
ICC15_RS05395	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ICC15_RS05400	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ICC15_RS05415	COG1555	photosystem II stabilization
ICC15_RS05420	COG0346	lactoylglutathione lyase activity
ICC15_RS05455	COG0488	(ABC) transporter
ICC15_RS05460	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICC15_RS05465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ICC15_RS05470	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICC15_RS05470	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICC15_RS05485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ICC15_RS05495	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ICC15_RS05525	COG0477	Major facilitator Superfamily
ICC15_RS05545	COG3335	DDE superfamily endonuclease
ICC15_RS05600	COG2801	Transposase and inactivated derivatives
ICC15_RS05605	COG2963	transposase activity
ICC15_RS05625	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS05635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICC15_RS05640	COG1758	RNA polymerase activity
ICC15_RS05645	COG0194	GDP metabolic process
ICC15_RS05650	COG1561	YicC-like family, N-terminal region
ICC15_RS05655	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ICC15_RS05660	COG1607	acyl-coa hydrolase
ICC15_RS05665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICC15_RS05675	COG1012	belongs to the aldehyde dehydrogenase family
ICC15_RS05680	COG3724	N-succinylarginine dihydrolase activity
ICC15_RS05720	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS05745	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ICC15_RS05760	COG4178	(ABC) transporter
ICC15_RS05770	COG1011	Hydrolase
ICC15_RS05775	COG1940	carbohydrate kinase activity
ICC15_RS05785	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICC15_RS05785	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICC15_RS05835	COG2801	Transposase and inactivated derivatives
ICC15_RS05840	COG2963	transposase activity
ICC15_RS05870	COG1214	PFAM Peptidase M22, glycoprotease
ICC15_RS05890	COG2719	SpoVR family
ICC15_RS05900	COG2766	serine protein kinase
ICC15_RS05910	COG2902	Dehydrogenase
ICC15_RS05915	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ICC15_RS05925	COG0616	signal peptide processing
ICC15_RS05930	COG0424	maF-like protein
ICC15_RS05950	COG0745	RESPONSE REGULATOR receiver
ICC15_RS05955	COG2205	protein histidine kinase activity
ICC15_RS05995	COG3293	Transposase
ICC15_RS06000	COG2166	iron-sulfur cluster assembly
ICC15_RS06015	COG2860	membrane
ICC15_RS06030	COG3335	DDE superfamily endonuclease
ICC15_RS06045	COG3335	DDE superfamily endonuclease
ICC15_RS06070	COG0784	Response regulator, receiver
ICC15_RS06070	COG0835	chemotaxis
ICC15_RS06075	COG3293	Transposase
ICC15_RS06095	COG1131	(ABC) transporter
ICC15_RS06100	COG0189	ligase activity
ICC15_RS06170	COG0358	DNA primase activity
ICC15_RS06175	COG1610	YqeY-like protein
ICC15_RS06180	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ICC15_RS06185	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ICC15_RS06190	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ICC15_RS06230	COG1621	beta-fructofuranosidase activity
ICC15_RS06255	COG0259	pyridoxamine-phosphate oxidase activity
ICC15_RS06260	COG0589	response to stress
ICC15_RS06270	COG1228	amidohydrolase
ICC15_RS06275	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ICC15_RS06280	COG2986	histidine ammonia-lyase
ICC15_RS06295	COG2963	transposase activity
ICC15_RS06300	COG2801	Transposase and inactivated derivatives
ICC15_RS06330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICC15_RS06335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICC15_RS06340	COG3956	TIGRFAM MazG family protein
ICC15_RS06350	COG3335	DDE superfamily endonuclease
ICC15_RS06360	COG0563	adenylate kinase activity
ICC15_RS06365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ICC15_RS06370	COG2223	nitrite transmembrane transporter activity
ICC15_RS06385	COG1278	Cold shock
ICC15_RS06390	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ICC15_RS06395	COG0542	response to heat
ICC15_RS06400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ICC15_RS06415	COG0492	ferredoxin-NADP+ reductase activity
ICC15_RS06420	COG1674	ftsk spoiiie
ICC15_RS06425	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ICC15_RS06440	COG3335	DDE superfamily endonuclease
ICC15_RS06455	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS06465	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ICC15_RS06470	COG1104	cysteine desulfurase activity
ICC15_RS06480	COG0105	UTP biosynthetic process
ICC15_RS06485	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ICC15_RS06505	COG0124	histidyl-tRNA synthetase
ICC15_RS06515	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICC15_RS06520	COG1160	GTP binding
ICC15_RS06530	COG1192	Involved in chromosome partitioning
ICC15_RS06540	COG0835	chemotaxis
ICC15_RS06560	COG2201	protein-glutamate methylesterase activity
ICC15_RS06570	COG1530	ribonuclease E activity
ICC15_RS06580	COG2918	glutathione biosynthetic process
ICC15_RS06585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICC15_RS06590	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ICC15_RS06595	COG0632	four-way junction helicase activity
ICC15_RS06605	COG0811	peptide transport
ICC15_RS06630	COG0823	Involved in the tonB-independent uptake of proteins
ICC15_RS06635	COG2885	chlorophyll binding
ICC15_RS06640	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ICC15_RS06645	COG0602	queuosine metabolic process
ICC15_RS06665	COG1570	exodeoxyribonuclease VII activity
ICC15_RS06670	COG1131	(ABC) transporter
ICC15_RS06675	COG0842	Transport permease protein
ICC15_RS06690	COG0442	prolyl-tRNA aminoacylation
ICC15_RS06705	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS06730	COG3335	DDE superfamily endonuclease
ICC15_RS06765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICC15_RS06770	COG0616	signal peptide processing
ICC15_RS06775	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ICC15_RS06825	COG1012	belongs to the aldehyde dehydrogenase family
ICC15_RS06840	COG5002	protein histidine kinase activity
ICC15_RS06840	COG0784	Response regulator, receiver
ICC15_RS06840	COG2205	protein histidine kinase activity
ICC15_RS06860	COG0183	Belongs to the thiolase family
ICC15_RS06880	COG1472	Belongs to the glycosyl hydrolase 3 family
ICC15_RS06885	COG0668	transmembrane transport
ICC15_RS06890	COG0598	Magnesium transport protein CorA
ICC15_RS06895	COG0318	PFAM AMP-dependent synthetase and ligase
ICC15_RS06905	COG2963	transposase activity
ICC15_RS06910	COG2801	Transposase and inactivated derivatives
ICC15_RS06920	COG3335	DDE superfamily endonuclease
ICC15_RS06930	COG2963	transposase activity
ICC15_RS06935	COG2801	Transposase and inactivated derivatives
ICC15_RS06950	COG3335	DDE superfamily endonuclease
ICC15_RS06965	COG3344	reverse transcriptase
ICC15_RS07000	COG3335	DDE superfamily endonuclease
ICC15_RS07010	COG3293	Transposase
ICC15_RS07030	COG0527	aspartate kinase activity
ICC15_RS07030	COG0460	homoserine dehydrogenase
ICC15_RS07040	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ICC15_RS07065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ICC15_RS07070	COG2814	Major facilitator Superfamily
ICC15_RS07075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ICC15_RS07180	COG3335	DDE superfamily endonuclease
ICC15_RS07200	COG2814	Major facilitator Superfamily
ICC15_RS07210	COG1074	ATP-dependent DNA helicase activity
ICC15_RS07215	COG2801	Transposase and inactivated derivatives
ICC15_RS07235	COG2801	Transposase and inactivated derivatives
ICC15_RS07280	COG2801	Transposase and inactivated derivatives
ICC15_RS07285	COG2963	transposase activity
ICC15_RS07315	COG2801	Transposase and inactivated derivatives
ICC15_RS07325	COG2963	transposase activity
ICC15_RS07350	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ICC15_RS07355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ICC15_RS07360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ICC15_RS07365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ICC15_RS07380	COG0360	Binds together with S18 to 16S ribosomal RNA
ICC15_RS07385	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICC15_RS07390	COG0359	binds to the 23S rRNA
ICC15_RS07395	COG0305	Participates in initiation and elongation during chromosome replication
ICC15_RS07435	COG1199	ATP-dependent helicase activity
ICC15_RS07440	COG0583	DNA-binding transcription factor activity
ICC15_RS07495	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ICC15_RS07510	COG1595	DNA-templated transcription, initiation
ICC15_RS07515	COG0481	GTPase activity
ICC15_RS07520	COG0681	Belongs to the peptidase S26 family
ICC15_RS07525	COG0571	ribonuclease III activity
ICC15_RS07535	COG1381	Involved in DNA repair and RecF pathway recombination
ICC15_RS07540	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ICC15_RS07545	COG0736	holo-[acyl-carrier-protein] synthase activity
ICC15_RS07555	COG2066	Belongs to the glutaminase family
ICC15_RS07565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ICC15_RS07570	COG1393	Belongs to the ArsC family
ICC15_RS07600	COG3335	DDE superfamily endonuclease
ICC15_RS07625	COG3335	DDE superfamily endonuclease
ICC15_RS07640	COG0531	amino acid
ICC15_RS07645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ICC15_RS07660	COG2022	thiamine diphosphate biosynthetic process
ICC15_RS07690	COG1181	Belongs to the D-alanine--D-alanine ligase family
ICC15_RS07715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ICC15_RS07725	COG0564	pseudouridine synthase activity
ICC15_RS07760	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ICC15_RS07780	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ICC15_RS07785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICC15_RS07790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICC15_RS07810	COG3344	reverse transcriptase
ICC15_RS07820	COG3344	reverse transcriptase
ICC15_RS07830	COG3335	DDE superfamily endonuclease
ICC15_RS07940	COG1376	ErfK ybiS ycfS ynhG family protein
ICC15_RS07960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICC15_RS07965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICC15_RS07970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICC15_RS08000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICC15_RS08000	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ICC15_RS08010	COG1393	Belongs to the ArsC family
ICC15_RS08015	COG0835	chemotaxis
ICC15_RS08015	COG0784	Response regulator, receiver
ICC15_RS08020	COG0604	alcohol dehydrogenase
ICC15_RS08020	COG1028	Short-chain dehydrogenase reductase Sdr
ICC15_RS08020	COG3321	synthase
ICC15_RS08075	COG1294	oxidase, subunit
ICC15_RS08085	COG3293	Transposase
ICC15_RS08095	COG3676	manually curated
ICC15_RS08145	COG0590	tRNA wobble adenosine to inosine editing
ICC15_RS08190	COG0513	Belongs to the DEAD box helicase family
ICC15_RS08205	COG0741	lytic transglycosylase activity
ICC15_RS08215	COG1054	Belongs to the UPF0176 family
ICC15_RS08220	COG3335	DDE superfamily endonuclease
ICC15_RS08225	COG2963	transposase activity
ICC15_RS08230	COG2801	Transposase and inactivated derivatives
ICC15_RS08285	COG0531	amino acid
ICC15_RS08315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ICC15_RS08330	COG3047	cAMP biosynthetic process
ICC15_RS08340	COG3293	Transposase
ICC15_RS08350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ICC15_RS08355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ICC15_RS08360	COG1845	cytochrome c oxidase, subunit III
ICC15_RS08365	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ICC15_RS08375	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS08405	COG3293	Transposase
ICC15_RS08430	COG2814	Major facilitator Superfamily
ICC15_RS08450	COG0814	amino acid
ICC15_RS08465	COG2890	protein-(glutamine-N5) methyltransferase activity
ICC15_RS08470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICC15_RS08475	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICC15_RS08480	COG0346	lactoylglutathione lyase activity
ICC15_RS08500	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS08520	COG0095	Lipoate-protein ligase
ICC15_RS08525	COG0739	heme binding
ICC15_RS08535	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ICC15_RS08545	COG0488	(ABC) transporter
ICC15_RS08575	COG0741	lytic transglycosylase activity
ICC15_RS08575	COG1388	LysM domain
ICC15_RS08610	COG1987	bacterial-type flagellum assembly
ICC15_RS08650	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ICC15_RS08655	COG0643	Histidine kinase
ICC15_RS08655	COG0784	Response regulator, receiver
ICC15_RS08655	COG2198	Histidine kinase
ICC15_RS08675	COG1959	2 iron, 2 sulfur cluster binding
ICC15_RS08680	COG0719	Fe-S assembly protein
ICC15_RS08685	COG0396	ATPase activity
ICC15_RS08690	COG0719	Fe-S assembly protein
ICC15_RS08695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICC15_RS08700	COG0316	Belongs to the HesB IscA family
ICC15_RS08705	COG2151	metal-sulfur cluster biosynthetic enzyme
ICC15_RS08720	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS08735	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS08775	COG0572	uridine kinase
ICC15_RS08780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ICC15_RS08830	COG2814	Major facilitator Superfamily
ICC15_RS08835	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ICC15_RS08840	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ICC15_RS08915	COG3293	Transposase
ICC15_RS08930	COG2095	MarC family integral membrane protein
ICC15_RS08940	COG2866	Carboxypeptidase
ICC15_RS08945	COG0513	Belongs to the DEAD box helicase family
ICC15_RS08950	COG4991	sh3 domain protein
ICC15_RS08950	COG3064	Membrane
ICC15_RS08950	COG0515	serine threonine protein kinase
ICC15_RS08975	COG3335	DDE superfamily endonuclease
ICC15_RS08980	COG2963	transposase activity
ICC15_RS09010	COG3676	manually curated
ICC15_RS09015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ICC15_RS09025	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ICC15_RS09030	COG0504	CTP synthase activity
ICC15_RS09035	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ICC15_RS09040	COG0148	phosphopyruvate hydratase activity
ICC15_RS09045	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ICC15_RS09050	COG0585	pseudouridine synthase activity
ICC15_RS09055	COG0531	amino acid
ICC15_RS09060	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ICC15_RS09065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICC15_RS09095	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ICC15_RS09125	COG2963	transposase activity
ICC15_RS09130	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS09150	COG1643	Atp-dependent helicase
ICC15_RS09175	COG0583	DNA-binding transcription factor activity
ICC15_RS09195	COG0658	competence protein
ICC15_RS09195	COG2333	competence protein COMEC
ICC15_RS09205	COG2963	transposase activity
ICC15_RS09225	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS09240	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS09260	COG0387	Pfam Sodium calcium exchanger
ICC15_RS09270	COG0686	Belongs to the AlaDH PNT family
ICC15_RS09290	COG2963	transposase activity
ICC15_RS09295	COG4232	protein-disulfide reductase activity
ICC15_RS09300	COG2801	Transposase and inactivated derivatives
ICC15_RS09305	COG2963	transposase activity
ICC15_RS09335	COG2963	transposase activity
ICC15_RS09360	COG0811	peptide transport
ICC15_RS09365	COG0848	biopolymer transport protein
ICC15_RS09370	COG1132	(ABC) transporter
ICC15_RS09375	COG1663	tetraacyldisaccharide 4'-kinase activity
ICC15_RS09385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ICC15_RS09395	COG0740	serine-type endopeptidase activity
ICC15_RS09400	COG1115	amino acid carrier protein
ICC15_RS09405	COG2801	Transposase and inactivated derivatives
ICC15_RS09410	COG2963	transposase activity
ICC15_RS09415	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS09440	COG0475	glutathione-regulated potassium exporter activity
ICC15_RS09440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ICC15_RS09445	COG3177	Filamentation induced by cAMP protein fic
ICC15_RS09455	COG4974	Belongs to the 'phage' integrase family
ICC15_RS09475	COG3335	DDE superfamily endonuclease
ICC15_RS09485	COG0583	DNA-binding transcription factor activity
ICC15_RS09520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ICC15_RS09560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICC15_RS09565	COG0477	Major facilitator Superfamily
ICC15_RS09570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICC15_RS09595	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ICC15_RS09600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ICC15_RS09645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICC15_RS09650	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICC15_RS09660	COG2963	transposase activity
ICC15_RS09665	COG2801	Transposase and inactivated derivatives
ICC15_RS09675	COG0835	chemotaxis
ICC15_RS09675	COG0784	Response regulator, receiver
ICC15_RS09710	COG0335	large ribosomal subunit rRNA binding
ICC15_RS09715	COG0336	Belongs to the RNA methyltransferase TrmD family
ICC15_RS09720	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ICC15_RS09730	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ICC15_RS09740	COG1902	pentaerythritol trinitrate reductase activity
ICC15_RS09740	COG0446	pyridine nucleotide-disulphide oxidoreductase
ICC15_RS09765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ICC15_RS09785	COG0811	peptide transport
ICC15_RS09790	COG4772	TonB-dependent receptor
ICC15_RS09795	COG1181	Belongs to the D-alanine--D-alanine ligase family
ICC15_RS09815	COG0019	diaminopimelate decarboxylase activity
ICC15_RS09820	COG1120	ATPase activity
ICC15_RS09870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICC15_RS09875	COG0557	exoribonuclease II activity
ICC15_RS09885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ICC15_RS09890	COG0330	HflC and HflK could
ICC15_RS09895	COG0330	HflC and HflK could
ICC15_RS09900	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICC15_RS09905	COG1923	regulation of RNA biosynthetic process
ICC15_RS09910	COG2271	Major facilitator Superfamily
ICC15_RS09915	COG0584	glycerophosphoryl diester phosphodiesterase
ICC15_RS09925	COG0531	amino acid
ICC15_RS09960	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ICC15_RS09965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICC15_RS09975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICC15_RS09985	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ICC15_RS10010	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ICC15_RS10025	COG3335	DDE superfamily endonuclease
ICC15_RS10045	COG5433	transposase activity
ICC15_RS10075	COG2081	HI0933 family
ICC15_RS10080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICC15_RS10090	COG1024	Enoyl-CoA hydratase
ICC15_RS10100	COG3501	Rhs element vgr protein
ICC15_RS10125	COG1960	acyl-CoA dehydrogenase activity
ICC15_RS10130	COG0183	Belongs to the thiolase family
ICC15_RS10135	COG1024	Enoyl-CoA hydratase
ICC15_RS10135	COG1250	3-hydroxyacyl-CoA dehydrogenase
ICC15_RS10170	COG3676	manually curated
ICC15_RS10185	COG2957	Belongs to the agmatine deiminase family
ICC15_RS10190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICC15_RS10200	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICC15_RS10230	COG2963	transposase activity
ICC15_RS10270	COG3335	DDE superfamily endonuclease
ICC15_RS10275	COG0717	Belongs to the dCTP deaminase family
ICC15_RS10280	COG0489	protein tyrosine kinase activity
ICC15_RS10315	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS10330	COG3335	DDE superfamily endonuclease
ICC15_RS10360	COG3335	DDE superfamily endonuclease
ICC15_RS10385	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ICC15_RS10390	COG0753	catalase activity
ICC15_RS10395	COG0783	Belongs to the Dps family
ICC15_RS10405	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS10415	COG0802	atpase or kinase
ICC15_RS10425	COG1162	GTPase activity
ICC15_RS10430	COG0688	phosphatidylethanolamine metabolic process
ICC15_RS10435	COG1671	Belongs to the UPF0178 family
ICC15_RS10440	COG0730	response to heat
ICC15_RS10445	COG3335	DDE superfamily endonuclease
ICC15_RS10470	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS10475	COG2963	transposase activity
ICC15_RS10480	COG2801	Transposase and inactivated derivatives
ICC15_RS10490	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ICC15_RS10495	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ICC15_RS10510	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ICC15_RS10520	COG2801	Transposase and inactivated derivatives
ICC15_RS10540	COG3344	reverse transcriptase
ICC15_RS10575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICC15_RS10575	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ICC15_RS10590	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ICC15_RS10595	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ICC15_RS10705	COG2805	Type II/IV secretion system protein
ICC15_RS10755	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ICC15_RS10765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICC15_RS10770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ICC15_RS10785	COG3655	Transcriptional regulator
ICC15_RS10805	COG2801	Transposase and inactivated derivatives
ICC15_RS10810	COG2963	transposase activity
ICC15_RS10820	COG2963	transposase activity
ICC15_RS10825	COG2801	Transposase and inactivated derivatives
ICC15_RS10850	COG3335	DDE superfamily endonuclease
ICC15_RS10880	COG0564	pseudouridine synthase activity
ICC15_RS10930	COG3335	DDE superfamily endonuclease
ICC15_RS10975	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS10990	COG1090	epimerase
ICC15_RS11000	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ICC15_RS11005	COG1876	peptidase activity
ICC15_RS11025	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ICC15_RS11030	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ICC15_RS11035	COG1862	Preprotein translocase
ICC15_RS11040	COG0343	queuine tRNA-ribosyltransferase activity
ICC15_RS11045	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ICC15_RS11055	COG0795	lipopolysaccharide-transporting ATPase activity
ICC15_RS11060	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ICC15_RS11070	COG0525	valine-tRNA ligase activity
ICC15_RS11075	COG2814	Major facilitator Superfamily
ICC15_RS11080	COG0288	reversible hydration of carbon dioxide
ICC15_RS11090	COG3344	reverse transcriptase
ICC15_RS11095	COG2801	Transposase and inactivated derivatives
ICC15_RS11100	COG2963	transposase activity
ICC15_RS11150	COG0405	Gamma-glutamyltransferase
ICC15_RS11165	COG1286	toxin biosynthetic process
ICC15_RS11170	COG0285	dihydrofolate synthase activity
ICC15_RS11175	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ICC15_RS11180	COG0101	tRNA pseudouridine synthase activity
ICC15_RS11190	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ICC15_RS11200	COG0488	(ABC) transporter
ICC15_RS11215	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS11265	COG3335	DDE superfamily endonuclease
ICC15_RS11270	COG3335	DDE superfamily endonuclease
ICC15_RS11280	COG3335	DDE superfamily endonuclease
ICC15_RS11290	COG0488	(ABC) transporter
ICC15_RS11300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICC15_RS11300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICC15_RS11310	COG0730	response to heat
ICC15_RS11325	COG3335	DDE superfamily endonuclease
ICC15_RS11335	COG0583	DNA-binding transcription factor activity
ICC15_RS11365	COG0326	Molecular chaperone. Has ATPase activity
ICC15_RS11380	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ICC15_RS11385	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ICC15_RS11420	COG0708	Exodeoxyribonuclease III
ICC15_RS11425	COG0733	neurotransmitter:sodium symporter activity
ICC15_RS11440	COG0850	regulation of cytokinetic process
ICC15_RS11445	COG2894	cell division
ICC15_RS11450	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ICC15_RS11455	COG4221	oxidoreductase activity
ICC15_RS11495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ICC15_RS11515	COG2963	transposase activity
ICC15_RS11570	COG3335	DDE superfamily endonuclease
ICC15_RS11590	COG4786	Flagellar basal body rod
ICC15_RS11590	COG1256	bacterial-type flagellum assembly
ICC15_RS11600	COG1706	bacterial-type flagellum-dependent cell motility
ICC15_RS11610	COG4786	Flagellar basal body rod
ICC15_RS11615	COG4787	bacterial-type flagellum-dependent cell motility
ICC15_RS11620	COG1749	Flagellar hook protein flgE
ICC15_RS11625	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ICC15_RS11655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICC15_RS11660	COG0482	sulfurtransferase activity
ICC15_RS11705	COG1360	Flagellar Motor Protein
ICC15_RS11710	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ICC15_RS11715	COG0142	geranyltranstransferase activity
ICC15_RS11720	COG1469	GTP cyclohydrolase I activity
ICC15_RS11745	COG3335	DDE superfamily endonuclease
ICC15_RS11830	COG0604	alcohol dehydrogenase
ICC15_RS11835	COG0714	Associated with various cellular activities
ICC15_RS11850	COG2304	oxidoreductase activity
ICC15_RS11915	COG3335	DDE superfamily endonuclease
ICC15_RS11940	COG3335	DDE superfamily endonuclease
ICC15_RS12025	COG0531	amino acid
ICC15_RS12030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ICC15_RS12045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICC15_RS12110	COG0500	methyltransferase
ICC15_RS12125	COG0450	alkyl hydroperoxide reductase
ICC15_RS12130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICC15_RS12140	COG4948	Mandelate Racemase Muconate Lactonizing
ICC15_RS12160	COG1058	Belongs to the CinA family
ICC15_RS12160	COG1546	Belongs to the CinA family
ICC15_RS12185	COG3104	oligopeptide transport
ICC15_RS12210	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS12220	COG3335	DDE superfamily endonuclease
ICC15_RS12230	COG3335	DDE superfamily endonuclease
ICC15_RS12245	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ICC15_RS12250	COG4988	ABC transporter
ICC15_RS12255	COG3150	esterase
ICC15_RS12260	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ICC15_RS12265	COG1538	Outer membrane efflux protein
ICC15_RS12270	COG0039	L-malate dehydrogenase activity
ICC15_RS12275	COG0494	nUDIX hydrolase
ICC15_RS12280	COG0776	regulation of translation
ICC15_RS12335	COG3335	DDE superfamily endonuclease
ICC15_RS12380	COG2801	Transposase and inactivated derivatives
ICC15_RS12395	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS12410	COG2801	Transposase and inactivated derivatives
ICC15_RS12420	COG0484	heat shock protein binding
ICC15_RS12435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ICC15_RS12510	COG4115	mRNA cleavage
ICC15_RS12520	COG4974	Belongs to the 'phage' integrase family
ICC15_RS12525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICC15_RS12535	COG3613	nucleoside 2-deoxyribosyltransferase
ICC15_RS12540	COG0717	Belongs to the dCTP deaminase family
ICC15_RS12615	COG0187	DNA topoisomerase II activity
ICC15_RS12670	COG1686	Belongs to the peptidase S11 family
ICC15_RS12680	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ICC15_RS12685	COG2274	protein secretion by the type I secretion system
ICC15_RS12690	COG2274	protein secretion by the type I secretion system
ICC15_RS12695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICC15_RS12705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICC15_RS12710	COG1560	Kdo2-lipid A biosynthetic process
ICC15_RS12725	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ICC15_RS12730	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ICC15_RS12735	COG0740	serine-type endopeptidase activity
ICC15_RS12740	COG0544	peptidyl-prolyl cis-trans isomerase activity
ICC15_RS12755	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ICC15_RS12765	COG0626	cystathionine gamma-synthase activity
ICC15_RS12780	COG0477	Major facilitator Superfamily
ICC15_RS12790	COG0656	L-ascorbic acid biosynthetic process
ICC15_RS12800	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS12835	COG0322	excinuclease ABC activity
ICC15_RS12840	COG2197	response regulator
ICC15_RS12855	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ICC15_RS12860	COG1538	Outer membrane efflux protein
ICC15_RS12865	COG2814	Major facilitator Superfamily
ICC15_RS12870	COG1566	PFAM secretion protein HlyD family protein
ICC15_RS12880	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ICC15_RS12905	COG0351	phosphomethylpyrimidine kinase
ICC15_RS12910	COG3842	ATPase activity
ICC15_RS12945	COG0047	phosphoribosylformylglycinamidine synthase activity
ICC15_RS12945	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICC15_RS12980	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS13065	COG3293	Transposase
ICC15_RS13075	COG2223	nitrite transmembrane transporter activity
ICC15_RS13115	COG0659	secondary active sulfate transmembrane transporter activity
ICC15_RS13120	COG0037	tRNA processing
ICC15_RS13125	COG0825	malonyl-CoA metabolic process
ICC15_RS13135	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICC15_RS13145	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICC15_RS13150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ICC15_RS13155	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICC15_RS13175	COG3425	synthase
ICC15_RS13190	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ICC15_RS13210	COG0575	Belongs to the CDS family
ICC15_RS13215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICC15_RS13220	COG0233	cytoplasmic translational termination
ICC15_RS13225	COG0528	UMP kinase activity
ICC15_RS13230	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ICC15_RS13235	COG0052	Belongs to the universal ribosomal protein uS2 family
ICC15_RS13250	COG0252	asparaginase activity
ICC15_RS13255	COG2171	N-acyltransferase activity
ICC15_RS13280	COG2814	Major facilitator Superfamily
ICC15_RS13285	COG2890	protein-(glutamine-N5) methyltransferase activity
ICC15_RS13290	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ICC15_RS13295	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ICC15_RS13315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICC15_RS13320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ICC15_RS13325	COG0193	aminoacyl-tRNA hydrolase activity
ICC15_RS13340	COG2226	methyltransferase
ICC15_RS13370	COG3104	oligopeptide transport
ICC15_RS13380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICC15_RS13385	COG0509	glycine decarboxylation via glycine cleavage system
ICC15_RS13390	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ICC15_RS13395	COG1519	Transferase
ICC15_RS13400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ICC15_RS13405	COG1215	transferase activity, transferring glycosyl groups
ICC15_RS13415	COG0859	PFAM glycosyl transferase family 9
ICC15_RS13430	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ICC15_RS13435	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ICC15_RS13440	COG3161	chorismate lyase activity
ICC15_RS13460	COG0277	FAD linked oxidase domain protein
ICC15_RS13460	COG0247	lactate metabolic process
ICC15_RS13465	COG2827	Endonuclease containing a URI domain
ICC15_RS13540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICC15_RS13545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ICC15_RS13550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ICC15_RS13555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ICC15_RS13560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICC15_RS13565	COG1028	Short-chain dehydrogenase reductase Sdr
ICC15_RS13570	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ICC15_RS13575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICC15_RS13580	COG0416	fatty acid biosynthetic process
ICC15_RS13585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ICC15_RS13595	COG2823	Periplasmic or secreted lipoprotein
ICC15_RS13600	COG3243	poly(R)-hydroxyalkanoic acid synthase
ICC15_RS13620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ICC15_RS13640	COG5007	Belongs to the BolA IbaG family
ICC15_RS13655	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ICC15_RS13660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ICC15_RS13665	COG1127	ABC transporter
ICC15_RS13670	COG0517	IMP dehydrogenase activity
ICC15_RS13670	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ICC15_RS13685	COG1137	ATPase activity
ICC15_RS13700	COG1660	Displays ATPase and GTPase activities
ICC15_RS13715	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ICC15_RS13725	COG0835	chemotaxis
ICC15_RS13725	COG0784	Response regulator, receiver
ICC15_RS13820	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ICC15_RS13825	COG0512	Glutamine amidotransferase of anthranilate synthase
ICC15_RS13830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ICC15_RS13845	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ICC15_RS13855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ICC15_RS13865	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ICC15_RS13870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICC15_RS13875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ICC15_RS13880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ICC15_RS13885	COG2967	ApaG domain
ICC15_RS13890	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ICC15_RS13900	COG3335	DDE superfamily endonuclease
ICC15_RS13945	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ICC15_RS13955	COG1530	ribonuclease E activity
ICC15_RS13960	COG0424	maF-like protein
ICC15_RS13970	COG1792	Involved in formation and maintenance of cell shape
ICC15_RS13975	COG1077	Cell shape determining protein MreB Mrl
ICC15_RS13980	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICC15_RS13985	COG0154	amidase activity
ICC15_RS13990	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICC15_RS14000	COG3335	DDE superfamily endonuclease
ICC15_RS14035	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS14060	COG1438	arginine binding
ICC15_RS14065	COG2871	sodium ion transport
ICC15_RS14070	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ICC15_RS14095	COG2183	response to ionizing radiation
ICC15_RS14105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ICC15_RS14110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICC15_RS14120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ICC15_RS14175	COG0835	chemotaxis
ICC15_RS14175	COG0784	Response regulator, receiver
ICC15_RS14180	COG0179	Fumarylacetoacetate (FAA) hydrolase
ICC15_RS14195	COG2884	Cell division ATP-binding protein ftsE
ICC15_RS14200	COG2177	Part of the ABC transporter FtsEX involved in
ICC15_RS14215	COG0114	fumarate hydratase activity
ICC15_RS14275	COG2801	Transposase and inactivated derivatives
ICC15_RS14280	COG2963	transposase activity
ICC15_RS14360	COG4974	Belongs to the 'phage' integrase family
ICC15_RS14395	COG1192	Involved in chromosome partitioning
ICC15_RS14425	COG2801	Transposase and inactivated derivatives
ICC15_RS14460	COG0629	single-stranded DNA binding
ICC15_RS14590	COG3023	N-Acetylmuramoyl-L-alanine amidase
ICC15_RS14665	COG0519	Catalyzes the synthesis of GMP from XMP
ICC15_RS14680	COG0069	glutamate synthase activity
ICC15_RS14715	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS14725	COG1881	PFAM PEBP family protein
ICC15_RS14735	COG0776	regulation of translation
ICC15_RS14740	COG0072	phenylalanine-tRNA ligase activity
ICC15_RS14740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICC15_RS14745	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ICC15_RS14755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ICC15_RS14765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ICC15_RS14785	COG2089	acid synthase
ICC15_RS14795	COG1083	cytidylyl-transferase
ICC15_RS14800	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ICC15_RS14805	COG1086	Polysaccharide biosynthesis protein
ICC15_RS14825	COG3335	DDE superfamily endonuclease
ICC15_RS14835	COG0556	nucleotide-excision repair
ICC15_RS14840	COG0436	Aminotransferase
ICC15_RS14845	COG0438	transferase activity, transferring glycosyl groups
ICC15_RS14870	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ICC15_RS14875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICC15_RS14880	COG1509	lysine 2,3-aminomutase activity
ICC15_RS14895	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ICC15_RS14905	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ICC15_RS14910	COG0142	geranyltranstransferase activity
ICC15_RS14915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ICC15_RS14925	COG0792	nuclease activity
ICC15_RS14930	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ICC15_RS14935	COG2969	positive regulation of protein catabolic process
ICC15_RS14940	COG0625	glutathione transferase activity
ICC15_RS14950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ICC15_RS14955	COG1918	ferrous iron import across plasma membrane
ICC15_RS15000	COG0045	succinate-CoA ligase (ADP-forming) activity
ICC15_RS15015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ICC15_RS15020	COG1053	succinate dehydrogenase
ICC15_RS15025	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ICC15_RS15030	COG2009	succinate dehydrogenase
ICC15_RS15065	COG3335	DDE superfamily endonuclease
ICC15_RS15100	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ICC15_RS15110	COG1677	Flagellar hook-basal body complex protein FliE
ICC15_RS15120	COG3852	Histidine kinase
ICC15_RS15130	COG0837	glucose binding
ICC15_RS15140	COG3335	DDE superfamily endonuclease
ICC15_RS15165	COG1113	amino acid transport
ICC15_RS15170	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS15190	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ICC15_RS15195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ICC15_RS15205	COG0308	aminopeptidase N
ICC15_RS15215	COG0500	methyltransferase
ICC15_RS15230	COG2205	protein histidine kinase activity
ICC15_RS15260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ICC15_RS15295	COG3335	DDE superfamily endonuclease
ICC15_RS15330	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS15375	COG0477	Major facilitator Superfamily
ICC15_RS15380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICC15_RS15390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ICC15_RS15420	COG0833	amino acid
ICC15_RS15430	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ICC15_RS15445	COG3335	DDE superfamily endonuclease
ICC15_RS15465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICC15_RS15470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICC15_RS15475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICC15_RS15500	COG1028	Short-chain dehydrogenase reductase Sdr
ICC15_RS15515	COG0084	hydrolase, TatD family'
ICC15_RS15550	COG0316	Belongs to the HesB IscA family
ICC15_RS15555	COG1981	membrane
ICC15_RS15615	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ICC15_RS15680	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ICC15_RS15690	COG0084	hydrolase, TatD family'
ICC15_RS15700	COG0456	acetyltransferase
ICC15_RS15710	COG1183	phosphatidylcholine synthase activity
ICC15_RS15765	COG0552	protein localization to endoplasmic reticulum
ICC15_RS15815	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ICC15_RS15820	COG3104	oligopeptide transport
ICC15_RS15850	COG3335	DDE superfamily endonuclease
ICC15_RS15870	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ICC15_RS15875	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ICC15_RS15875	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ICC15_RS15880	COG1301	dicarboxylic acid transport
ICC15_RS15905	COG2995	paraquat-inducible protein a
ICC15_RS15910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICC15_RS15915	COG4536	flavin adenine dinucleotide binding
ICC15_RS15920	COG0586	Pfam SNARE associated Golgi protein
ICC15_RS15930	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ICC15_RS15950	COG2011	ABC-type metal ion transport system permease component
ICC15_RS15955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICC15_RS15960	COG2925	Exonuclease
ICC15_RS15980	COG0531	amino acid
ICC15_RS15985	COG0745	RESPONSE REGULATOR receiver
ICC15_RS15990	COG0784	Response regulator, receiver
ICC15_RS15990	COG0835	chemotaxis
ICC15_RS16010	COG0006	proline dipeptidase activity
ICC15_RS16015	COG0151	Belongs to the GarS family
ICC15_RS16020	COG0138	bifunctional purine biosynthesis protein purh
ICC15_RS16025	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ICC15_RS16040	COG0439	Biotin carboxylase
ICC15_RS16045	COG0511	ligase activity, forming carbon-carbon bonds
ICC15_RS16055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ICC15_RS16080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICC15_RS16085	COG0508	dehydrogenase complex catalyzes the overall conversion of
ICC15_RS16095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICC15_RS16100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICC15_RS16105	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ICC15_RS16115	COG1534	Rna-binding protein
ICC15_RS16150	COG2119	membrane
ICC15_RS16155	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ICC15_RS16175	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ICC15_RS16205	COG0259	pyridoxamine-phosphate oxidase activity
ICC15_RS16215	COG3335	DDE superfamily endonuclease
ICC15_RS16245	COG3335	DDE superfamily endonuclease
ICC15_RS16270	COG0788	formyltetrahydrofolate deformylase activity
ICC15_RS16280	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ICC15_RS16295	COG0210	DNA helicase
ICC15_RS16310	COG2027	D-alanyl-D-alanine carboxypeptidase
ICC15_RS16315	COG2027	D-alanyl-D-alanine carboxypeptidase
ICC15_RS16330	COG1054	Belongs to the UPF0176 family
ICC15_RS16340	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ICC15_RS16345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ICC15_RS16350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ICC15_RS16375	COG3335	DDE superfamily endonuclease
ICC15_RS16385	COG3335	DDE superfamily endonuclease
ICC15_RS16400	COG3335	DDE superfamily endonuclease
ICC15_RS16445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICC15_RS16450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICC15_RS16470	COG0318	PFAM AMP-dependent synthetase and ligase
ICC15_RS16480	COG0531	amino acid
ICC15_RS16490	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS16495	COG0210	DNA helicase
ICC15_RS16505	COG0583	DNA-binding transcription factor activity
ICC15_RS16570	COG5002	protein histidine kinase activity
ICC15_RS16575	COG0745	RESPONSE REGULATOR receiver
ICC15_RS16580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICC15_RS16585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICC15_RS16590	COG1278	Cold shock
ICC15_RS16595	COG2885	chlorophyll binding
ICC15_RS16595	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ICC15_RS16605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ICC15_RS16640	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ICC15_RS16650	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ICC15_RS16665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ICC15_RS16670	COG3206	protein involved in exopolysaccharide biosynthesis
ICC15_RS16670	COG0489	protein tyrosine kinase activity
ICC15_RS16770	COG2801	Transposase and inactivated derivatives
ICC15_RS16795	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ICC15_RS16805	COG1294	oxidase, subunit
ICC15_RS16815	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ICC15_RS16815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICC15_RS16855	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ICC15_RS16860	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ICC15_RS16865	COG1294	oxidase, subunit
ICC15_RS16875	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ICC15_RS16875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICC15_RS16990	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS17030	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICC15_RS17050	COG2963	transposase activity
ICC15_RS17075	COG0477	Major facilitator Superfamily
ICC15_RS17120	COG1192	Involved in chromosome partitioning
ICC15_RS17130	COG0724	RNA recognition motif
ICC15_RS17155	COG3335	DDE superfamily endonuclease
ICC15_RS17220	COG3177	Filamentation induced by cAMP protein fic
ICC15_RS17285	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS17395	COG0629	single-stranded DNA binding
ICC15_RS17405	COG4456	Virulence-associated protein
ICC15_RS17410	COG1487	ribonuclease activity
ICC15_RS17460	COG1802	Transcriptional regulator
ICC15_RS17460	COG4626	Terminase
ICC15_RS17470	COG0740	serine-type endopeptidase activity
ICC15_RS17685	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS17690	COG0724	RNA recognition motif
ICC15_RS17700	COG1192	Involved in chromosome partitioning
ICC15_RS17720	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS17755	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICC15_RS17825	COG0629	single-stranded DNA binding
ICC15_RS17850	COG1802	Transcriptional regulator
ICC15_RS17850	COG4626	Terminase
ICC15_RS17860	COG0740	serine-type endopeptidase activity
ICC15_RS17970	COG0724	RNA recognition motif
ICC15_RS17980	COG1192	Involved in chromosome partitioning
ICC15_RS18020	COG0477	Major facilitator Superfamily
ICC15_RS18040	COG4106	trans-aconitate 2-methyltransferase activity
ICC15_RS18075	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS18100	COG0724	RNA recognition motif
ICC15_RS18110	COG1192	Involved in chromosome partitioning
ICC15_RS18190	COG4946	Tricorn protease homolog
ICC15_RS18190	COG1506	peptidase
ICC15_RS18190	COG0823	Involved in the tonB-independent uptake of proteins
ICC15_RS18195	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS18200	COG1598	PFAM Uncharacterised protein family UPF0150
ICC15_RS18210	COG4974	Belongs to the 'phage' integrase family
ICC15_RS18250	COG1598	PFAM Uncharacterised protein family UPF0150
ICC15_RS18255	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS18335	COG4974	Belongs to the 'phage' integrase family
ICC15_RS18345	COG1598	PFAM Uncharacterised protein family UPF0150
ICC15_RS18350	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS18390	COG4974	Belongs to the 'phage' integrase family
ICC15_RS18400	COG1475	DNA binding
ICC15_RS18405	COG1192	Involved in chromosome partitioning
ICC15_RS18480	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS18505	COG0823	Involved in the tonB-independent uptake of proteins
ICC15_RS18505	COG1506	peptidase
ICC15_RS18505	COG4946	Tricorn protease homolog
ICC15_RS18575	COG0740	serine-type endopeptidase activity
ICC15_RS18605	COG4974	Belongs to the 'phage' integrase family
ICC15_RS18660	COG1192	Involved in chromosome partitioning
ICC15_RS18685	COG3344	reverse transcriptase
ICC15_RS18700	COG4974	Belongs to the 'phage' integrase family
ICC15_RS18755	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS18815	COG0784	Response regulator, receiver
ICC15_RS18815	COG0835	chemotaxis
ICC15_RS18915	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS18955	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS18975	COG2963	transposase activity
ICC15_RS18985	COG2801	Transposase and inactivated derivatives
ICC15_RS19040	COG3335	DDE superfamily endonuclease
ICC15_RS19065	COG2336	PFAM SpoVT AbrB
ICC15_RS19135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ICC15_RS19170	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS19230	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ICC15_RS19250	COG2963	transposase activity
ICC15_RS19255	COG2801	Transposase and inactivated derivatives
ICC15_RS19260	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS19325	COG2963	transposase activity
ICC15_RS19375	COG3335	DDE superfamily endonuclease
ICC15_RS19385	COG3344	reverse transcriptase
ICC15_RS19460	COG3335	DDE superfamily endonuclease
ICC15_RS19500	COG3335	DDE superfamily endonuclease
ICC15_RS19515	COG1192	Involved in chromosome partitioning
ICC15_RS19545	COG0740	serine-type endopeptidase activity
ICC15_RS19550	COG2963	transposase activity
ICC15_RS19570	COG4974	Belongs to the 'phage' integrase family
ICC15_RS19580	COG4115	mRNA cleavage
ICC15_RS19595	COG2801	Transposase and inactivated derivatives
ICC15_RS19605	COG2963	transposase activity
ICC15_RS19660	COG2337	Toxic component of a toxin-antitoxin (TA) module
ICC15_RS19665	COG0724	RNA recognition motif
ICC15_RS19745	COG3344	reverse transcriptase
ICC15_RS19765	COG3335	DDE superfamily endonuclease
ICC15_RS19810	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS19870	COG4974	Belongs to the 'phage' integrase family
ICC15_RS19890	COG2963	transposase activity
ICC15_RS19975	COG2826	transposase and inactivated derivatives, IS30 family
ICC15_RS19980	COG3335	DDE superfamily endonuclease
ICC15_RS20050	COG2801	Transposase and inactivated derivatives