locus-tag	class	description
Pan110_RS00010	COG0592	DNA-directed DNA polymerase activity
Pan110_RS00020	COG0187	DNA topoisomerase II activity
Pan110_RS00025	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Pan110_RS00030	COG0585	pseudouridine synthase activity
Pan110_RS00040	COG1556	Lactate utilization protein
Pan110_RS00045	COG1139	Iron-sulfur cluster binding protein
Pan110_RS00055	COG0667	Aldo Keto reductase
Pan110_RS00070	COG4864	UPF0365 protein
Pan110_RS00080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Pan110_RS00090	COG0657	acetylesterase activity
Pan110_RS00110	COG2755	lipolytic protein G-D-S-L family
Pan110_RS00155	COG3119	arylsulfatase activity
Pan110_RS00220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Pan110_RS00250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Pan110_RS00260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Pan110_RS00275	COG0443	Heat shock 70 kDa protein
Pan110_RS00365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Pan110_RS00370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Pan110_RS00385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Pan110_RS00395	COG1459	type II secretion system
Pan110_RS00400	COG1459	type II secretion system
Pan110_RS00425	COG4974	Belongs to the 'phage' integrase family
Pan110_RS00440	COG0187	DNA topoisomerase II activity
Pan110_RS00445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Pan110_RS00595	COG2815	serine threonine protein kinase
Pan110_RS00595	COG0515	serine threonine protein kinase
Pan110_RS00635	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Pan110_RS00655	COG2022	thiamine diphosphate biosynthetic process
Pan110_RS00665	COG0584	glycerophosphoryl diester phosphodiesterase
Pan110_RS00670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS00680	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Pan110_RS00690	COG1691	(AIR) carboxylase
Pan110_RS00695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Pan110_RS00700	COG5285	phytanoyl-CoA dioxygenase
Pan110_RS00715	COG1181	Belongs to the D-alanine--D-alanine ligase family
Pan110_RS00775	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Pan110_RS00775	COG0517	IMP dehydrogenase activity
Pan110_RS00780	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Pan110_RS00800	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Pan110_RS00820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Pan110_RS00825	COG1609	Transcriptional regulator
Pan110_RS00825	COG2207	Transcriptional regulator
Pan110_RS00835	COG0519	Catalyzes the synthesis of GMP from XMP
Pan110_RS00880	COG3119	arylsulfatase activity
Pan110_RS00935	COG1518	maintenance of DNA repeat elements
Pan110_RS00935	COG1468	defense response to virus
Pan110_RS00940	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Pan110_RS00970	COG2433	Pfam Transposase IS66
Pan110_RS01005	COG1696	Membrane protein involved in D-alanine export
Pan110_RS01110	COG3220	belongs to the UPF0276 family
Pan110_RS01150	COG2200	EAL domain
Pan110_RS01235	COG3328	transposase activity
Pan110_RS01250	COG3328	transposase activity
Pan110_RS01265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Pan110_RS01285	COG0842	Transport permease protein
Pan110_RS01290	COG0842	Transport permease protein
Pan110_RS01295	COG1131	(ABC) transporter
Pan110_RS01310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Pan110_RS01320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Pan110_RS01355	COG0107	imidazoleglycerol-phosphate synthase activity
Pan110_RS01410	COG0436	Aminotransferase
Pan110_RS01425	COG0438	transferase activity, transferring glycosyl groups
Pan110_RS01460	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Pan110_RS01465	COG4591	ABC-type transport system involved in lipoprotein release permease component
Pan110_RS01470	COG1136	(ABC) transporter
Pan110_RS01550	COG0714	Associated with various cellular activities
Pan110_RS01570	COG2017	converts alpha-aldose to the beta-anomer
Pan110_RS01575	COG1678	Uncharacterized ACR, COG1678
Pan110_RS01585	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Pan110_RS01590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Pan110_RS01660	COG2204	response regulator
Pan110_RS01670	COG0714	Associated with various cellular activities
Pan110_RS01725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Pan110_RS01760	COG1136	(ABC) transporter
Pan110_RS01760	COG0577	efflux transmembrane transporter activity
Pan110_RS01765	COG1136	(ABC) transporter
Pan110_RS01770	COG1376	ErfK ybiS ycfS ynhG family protein
Pan110_RS01775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Pan110_RS01780	COG0166	Belongs to the GPI family
Pan110_RS01785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Pan110_RS01820	COG0811	peptide transport
Pan110_RS01865	COG1073	alpha beta
Pan110_RS01905	COG0006	proline dipeptidase activity
Pan110_RS01910	COG0511	ligase activity, forming carbon-carbon bonds
Pan110_RS01915	COG0439	Biotin carboxylase
Pan110_RS01940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Pan110_RS01950	COG0277	FAD linked oxidase domain protein
Pan110_RS01995	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Pan110_RS02000	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Pan110_RS02010	COG1028	Short-chain dehydrogenase reductase Sdr
Pan110_RS02015	COG3608	succinylglutamate desuccinylase aspartoacylase
Pan110_RS02020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Pan110_RS02025	COG0668	transmembrane transport
Pan110_RS02030	COG1940	carbohydrate kinase activity
Pan110_RS02055	COG3706	GGDEF domain
Pan110_RS02060	COG0745	RESPONSE REGULATOR receiver
Pan110_RS02070	COG2197	response regulator
Pan110_RS02075	COG0667	Aldo Keto reductase
Pan110_RS02080	COG2135	peptidase activity
Pan110_RS02095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Pan110_RS02110	COG0495	leucyl-tRNA aminoacylation
Pan110_RS02135	COG1943	Transposase
Pan110_RS02150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Pan110_RS02170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Pan110_RS02185	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Pan110_RS02190	COG1058	Belongs to the CinA family
Pan110_RS02190	COG1546	Belongs to the CinA family
Pan110_RS02205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Pan110_RS02205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Pan110_RS02210	COG3876	Protein conserved in bacteria
Pan110_RS02230	COG0805	protein transport
Pan110_RS02245	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Pan110_RS02250	COG0459	protein refolding
Pan110_RS02255	COG0137	argininosuccinate synthase activity
Pan110_RS02265	COG1012	belongs to the aldehyde dehydrogenase family
Pan110_RS02275	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Pan110_RS02300	COG3119	arylsulfatase activity
Pan110_RS02320	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Pan110_RS02325	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Pan110_RS02330	COG1722	exodeoxyribonuclease VII activity
Pan110_RS02335	COG1570	exodeoxyribonuclease VII activity
Pan110_RS02350	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Pan110_RS02365	COG3273	potassium ion transport
Pan110_RS02365	COG0471	metal ion transport
Pan110_RS02370	COG1218	3'(2'),5'-bisphosphate nucleotidase
Pan110_RS02375	COG0673	inositol 2-dehydrogenase activity
Pan110_RS02380	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Pan110_RS02390	COG1530	ribonuclease E activity
Pan110_RS02405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Pan110_RS02435	COG3706	GGDEF domain
Pan110_RS02440	COG1414	Transcriptional regulator
Pan110_RS02470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Pan110_RS02475	COG1321	iron dependent repressor
Pan110_RS02475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Pan110_RS02480	COG1121	(ABC) transporter
Pan110_RS02485	COG0803	Belongs to the bacterial solute-binding protein 9 family
Pan110_RS02490	COG0657	acetylesterase activity
Pan110_RS02495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Pan110_RS02500	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Pan110_RS02505	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Pan110_RS02510	COG4555	ABC transporter
Pan110_RS02515	COG1668	transmembrane transport
Pan110_RS02520	COG0402	S-adenosylhomocysteine deaminase activity
Pan110_RS02530	COG0456	acetyltransferase
Pan110_RS02540	COG2226	methyltransferase
Pan110_RS02545	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Pan110_RS02550	COG2815	serine threonine protein kinase
Pan110_RS02550	COG0515	serine threonine protein kinase
Pan110_RS02570	COG1663	tetraacyldisaccharide 4'-kinase activity
Pan110_RS02585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Pan110_RS02595	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Pan110_RS02605	COG0517	IMP dehydrogenase activity
Pan110_RS02605	COG0516	GMP reductase activity
Pan110_RS02610	COG0233	cytoplasmic translational termination
Pan110_RS02615	COG0126	phosphoglycerate kinase activity
Pan110_RS02620	COG5285	phytanoyl-CoA dioxygenase
Pan110_RS02630	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Pan110_RS02645	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Pan110_RS02650	COG5002	protein histidine kinase activity
Pan110_RS02655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Pan110_RS02660	COG0573	inorganic phosphate transmembrane transporter activity
Pan110_RS02670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Pan110_RS02675	COG0704	Plays a role in the regulation of phosphate uptake
Pan110_RS02680	COG0745	RESPONSE REGULATOR receiver
Pan110_RS02715	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Pan110_RS02720	COG0840	transmembrane signaling receptor activity
Pan110_RS02740	COG2207	Transcriptional regulator
Pan110_RS02740	COG1609	Transcriptional regulator
Pan110_RS02745	COG0673	inositol 2-dehydrogenase activity
Pan110_RS02780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Pan110_RS02785	COG0673	inositol 2-dehydrogenase activity
Pan110_RS02790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Pan110_RS02795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Pan110_RS02805	COG1077	Cell shape determining protein MreB Mrl
Pan110_RS02820	COG0768	penicillin binding
Pan110_RS02825	COG1785	Belongs to the alkaline phosphatase family
Pan110_RS02835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Pan110_RS02845	COG1011	Hydrolase
Pan110_RS02870	COG0174	glutamine synthetase
Pan110_RS02875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Pan110_RS02885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Pan110_RS02885	COG1333	cytochrome c biogenesis protein
Pan110_RS02895	COG3118	belongs to the thioredoxin family
Pan110_RS02910	COG0284	orotidine-5'-phosphate decarboxylase activity
Pan110_RS02915	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Pan110_RS02920	COG0604	alcohol dehydrogenase
Pan110_RS02940	COG4948	Mandelate Racemase Muconate Lactonizing
Pan110_RS02995	COG1595	DNA-templated transcription, initiation
Pan110_RS03005	COG1090	epimerase
Pan110_RS03020	COG0657	acetylesterase activity
Pan110_RS03090	COG2755	lipolytic protein G-D-S-L family
Pan110_RS03115	COG0742	ribosomal rna small subunit methyltransferase
Pan110_RS03125	COG0745	RESPONSE REGULATOR receiver
Pan110_RS03135	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Pan110_RS03165	COG0673	inositol 2-dehydrogenase activity
Pan110_RS03185	COG2211	Major facilitator Superfamily
Pan110_RS03200	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Pan110_RS03200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Pan110_RS03205	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Pan110_RS03210	COG0673	inositol 2-dehydrogenase activity
Pan110_RS03215	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Pan110_RS03225	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Pan110_RS03245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Pan110_RS03265	COG0339	signal peptide processing
Pan110_RS03290	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Pan110_RS03300	COG0159	tryptophan synthase activity
Pan110_RS03305	COG0133	tryptophan synthase activity
Pan110_RS03325	COG0686	Belongs to the AlaDH PNT family
Pan110_RS03345	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Pan110_RS03345	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Pan110_RS03350	COG0859	PFAM glycosyl transferase family 9
Pan110_RS03375	COG3408	Glycogen debranching enzyme
Pan110_RS03375	COG3119	arylsulfatase activity
Pan110_RS03380	COG0012	GTP binding
Pan110_RS03385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Pan110_RS03425	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Pan110_RS03490	COG0446	pyridine nucleotide-disulphide oxidoreductase
Pan110_RS03500	COG0604	alcohol dehydrogenase
Pan110_RS03530	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Pan110_RS03535	COG0602	queuosine metabolic process
Pan110_RS03540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Pan110_RS03545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Pan110_RS03625	COG0745	RESPONSE REGULATOR receiver
Pan110_RS03630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Pan110_RS03685	COG2169	Transcriptional regulator
Pan110_RS03685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Pan110_RS03720	COG1073	alpha beta
Pan110_RS03725	COG3119	arylsulfatase activity
Pan110_RS03735	COG0322	excinuclease ABC activity
Pan110_RS03740	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Pan110_RS03745	COG1473	amidohydrolase
Pan110_RS03755	COG1940	carbohydrate kinase activity
Pan110_RS03770	COG0698	ribose 5-phosphate isomerase
Pan110_RS03800	COG4565	transcriptional regulatory protein
Pan110_RS03810	COG0673	inositol 2-dehydrogenase activity
Pan110_RS03870	COG0477	Major facilitator Superfamily
Pan110_RS03920	COG0564	pseudouridine synthase activity
Pan110_RS03930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Pan110_RS03950	COG2078	PFAM AMMECR1 domain protein
Pan110_RS03970	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Pan110_RS03975	COG0386	Belongs to the glutathione peroxidase family
Pan110_RS04055	COG1196	nuclear chromosome segregation
Pan110_RS04065	COG0142	geranyltranstransferase activity
Pan110_RS04075	COG4536	flavin adenine dinucleotide binding
Pan110_RS04085	COG0443	Heat shock 70 kDa protein
Pan110_RS04090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Pan110_RS04110	COG2814	Major facilitator Superfamily
Pan110_RS04125	COG1247	-acetyltransferase
Pan110_RS04165	COG2815	serine threonine protein kinase
Pan110_RS04165	COG0515	serine threonine protein kinase
Pan110_RS04195	COG4145	pantothenate transmembrane transporter activity
Pan110_RS04225	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Pan110_RS04230	COG4786	Flagellar basal body rod
Pan110_RS04235	COG4786	Flagellar basal body rod
Pan110_RS04245	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Pan110_RS04250	COG1706	bacterial-type flagellum-dependent cell motility
Pan110_RS04275	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Pan110_RS04285	COG2239	Acts as a magnesium transporter
Pan110_RS04305	COG1160	GTP binding
Pan110_RS04315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Pan110_RS04315	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Pan110_RS04360	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Pan110_RS04365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Pan110_RS04370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Pan110_RS04375	COG1120	ATPase activity
Pan110_RS04395	COG2322	membrane
Pan110_RS04405	COG1131	(ABC) transporter
Pan110_RS04415	COG1845	cytochrome c oxidase, subunit III
Pan110_RS04420	COG0109	protoheme IX farnesyltransferase activity
Pan110_RS04435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Pan110_RS04455	COG2329	Antibiotic biosynthesis monooxygenase
Pan110_RS04475	COG0067	glutamate synthase
Pan110_RS04475	COG0069	glutamate synthase activity
Pan110_RS04475	COG0070	glutamate synthase
Pan110_RS04480	COG0493	'glutamate synthase
Pan110_RS04590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Pan110_RS04590	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Pan110_RS04600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Pan110_RS04610	COG0673	inositol 2-dehydrogenase activity
Pan110_RS04620	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Pan110_RS04635	COG1450	Type ii and iii secretion system protein
Pan110_RS04650	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Pan110_RS04695	COG1562	ergosterol biosynthetic process
Pan110_RS04725	COG1408	metallophosphoesterase
Pan110_RS04735	COG0438	transferase activity, transferring glycosyl groups
Pan110_RS04750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Pan110_RS04755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Pan110_RS04770	COG0482	sulfurtransferase activity
Pan110_RS04775	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Pan110_RS04820	COG1560	Kdo2-lipid A biosynthetic process
Pan110_RS04825	COG2146	nitrite reductase [NAD(P)H] activity
Pan110_RS04830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Pan110_RS04850	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Pan110_RS04855	COG0632	four-way junction helicase activity
Pan110_RS04860	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Pan110_RS04865	COG0215	cysteine-tRNA ligase activity
Pan110_RS04895	COG0385	Bile acid
Pan110_RS04900	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Pan110_RS04905	COG2226	methyltransferase
Pan110_RS04910	COG0163	prenyltransferase activity
Pan110_RS04915	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Pan110_RS04925	COG1228	amidohydrolase
Pan110_RS04970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Pan110_RS04990	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Pan110_RS04995	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Pan110_RS05005	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Pan110_RS05010	COG2183	response to ionizing radiation
Pan110_RS05020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Pan110_RS05030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Pan110_RS05040	COG1802	Transcriptional regulator
Pan110_RS05050	COG2835	tetraacyldisaccharide 4'-kinase activity
Pan110_RS05050	COG1663	tetraacyldisaccharide 4'-kinase activity
Pan110_RS05070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Pan110_RS05080	COG3386	PFAM SMP-30 Gluconolaconase
Pan110_RS05095	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Pan110_RS05120	COG1131	(ABC) transporter
Pan110_RS05130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Pan110_RS05160	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
Pan110_RS05165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Pan110_RS05170	COG1595	DNA-templated transcription, initiation
Pan110_RS05205	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Pan110_RS05250	COG1393	Belongs to the ArsC family
Pan110_RS05260	COG0673	inositol 2-dehydrogenase activity
Pan110_RS05300	COG0483	inositol monophosphate 1-phosphatase activity
Pan110_RS05315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS05320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS05365	COG0714	Associated with various cellular activities
Pan110_RS05370	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Pan110_RS05375	COG0287	Prephenate dehydrogenase
Pan110_RS05400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Pan110_RS05445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Pan110_RS05450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Pan110_RS05450	COG0574	Belongs to the PEP-utilizing enzyme family
Pan110_RS05465	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Pan110_RS05485	COG0631	protein serine/threonine phosphatase activity
Pan110_RS05490	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Pan110_RS05520	COG1115	amino acid carrier protein
Pan110_RS05535	COG0719	Fe-S assembly protein
Pan110_RS05540	COG0719	Fe-S assembly protein
Pan110_RS05555	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Pan110_RS05560	COG0154	amidase activity
Pan110_RS05565	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Pan110_RS05570	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Pan110_RS05575	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Pan110_RS05585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Pan110_RS05585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Pan110_RS05610	COG1904	glucuronate isomerase
Pan110_RS05620	COG2208	phosphoserine phosphatase activity
Pan110_RS05620	COG2770	Histidine kinase
Pan110_RS05640	COG1595	DNA-templated transcription, initiation
Pan110_RS05670	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Pan110_RS05675	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Pan110_RS05680	COG0509	glycine decarboxylation via glycine cleavage system
Pan110_RS05685	COG0698	ribose 5-phosphate isomerase
Pan110_RS05690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Pan110_RS05695	COG2226	methyltransferase
Pan110_RS05705	COG0189	ligase activity
Pan110_RS05710	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
Pan110_RS05715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Pan110_RS05725	COG4336	lyase activity
Pan110_RS05730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Pan110_RS05740	COG0670	Belongs to the BI1 family
Pan110_RS05745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Pan110_RS05755	COG0564	pseudouridine synthase activity
Pan110_RS05760	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Pan110_RS05805	COG2208	phosphoserine phosphatase activity
Pan110_RS05825	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Pan110_RS05835	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Pan110_RS05840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Pan110_RS05845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Pan110_RS05850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Pan110_RS05860	COG0195	Participates in both transcription termination and antitermination
Pan110_RS05865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Pan110_RS05865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Pan110_RS05870	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Pan110_RS05885	COG0217	transcriptional regulatory protein
Pan110_RS05905	COG2255	four-way junction helicase activity
Pan110_RS05910	COG0445	tRNA wobble uridine modification
Pan110_RS05915	COG0745	RESPONSE REGULATOR receiver
Pan110_RS05920	COG3852	Histidine kinase
Pan110_RS05925	COG1757	Na H antiporter
Pan110_RS05930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Pan110_RS05935	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Pan110_RS05940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS05945	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Pan110_RS05970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Pan110_RS05980	COG3119	arylsulfatase activity
Pan110_RS06000	COG3119	arylsulfatase activity
Pan110_RS06010	COG0442	prolyl-tRNA aminoacylation
Pan110_RS06015	COG3481	metal-dependent phosphohydrolase, HD sub domain
Pan110_RS06020	COG0557	exoribonuclease II activity
Pan110_RS06030	COG1053	succinate dehydrogenase
Pan110_RS06035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Pan110_RS06040	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Pan110_RS06065	COG1131	(ABC) transporter
Pan110_RS06070	COG0167	dihydroorotate dehydrogenase activity
Pan110_RS06075	COG0793	Belongs to the peptidase S41A family
Pan110_RS06110	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Pan110_RS06115	COG0142	geranyltranstransferase activity
Pan110_RS06130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Pan110_RS06140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Pan110_RS06145	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Pan110_RS06150	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Pan110_RS06155	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Pan110_RS06190	COG1073	alpha beta
Pan110_RS06200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Pan110_RS06205	COG0673	inositol 2-dehydrogenase activity
Pan110_RS06225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Pan110_RS06245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Pan110_RS06250	COG0193	aminoacyl-tRNA hydrolase activity
Pan110_RS06265	COG0359	binds to the 23S rRNA
Pan110_RS06270	COG0305	Participates in initiation and elongation during chromosome replication
Pan110_RS06280	COG1012	belongs to the aldehyde dehydrogenase family
Pan110_RS06320	COG1943	Transposase
Pan110_RS06325	COG0745	RESPONSE REGULATOR receiver
Pan110_RS06330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Pan110_RS06335	COG3385	transposase activity
Pan110_RS06345	COG0045	succinate-CoA ligase (ADP-forming) activity
Pan110_RS06350	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Pan110_RS06355	COG0105	UTP biosynthetic process
Pan110_RS06360	COG0505	Belongs to the CarA family
Pan110_RS06365	COG0640	Transcriptional regulator
Pan110_RS06370	COG1028	Short-chain dehydrogenase reductase Sdr
Pan110_RS06400	COG1690	Belongs to the RtcB family
Pan110_RS06430	COG0673	inositol 2-dehydrogenase activity
Pan110_RS06440	COG1283	sodium-dependent phosphate transmembrane transporter activity
Pan110_RS06495	COG0401	homolog of Blt101
Pan110_RS06525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Pan110_RS06535	COG1278	Cold shock
Pan110_RS06545	COG0513	Belongs to the DEAD box helicase family
Pan110_RS06590	COG3119	arylsulfatase activity
Pan110_RS06595	COG3228	Belongs to the MtfA family
Pan110_RS06620	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
Pan110_RS06635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Pan110_RS06640	COG0318	PFAM AMP-dependent synthetase and ligase
Pan110_RS06655	COG3119	arylsulfatase activity
Pan110_RS06695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Pan110_RS06720	COG4941	Belongs to the sigma-70 factor family
Pan110_RS06750	COG3795	YCII-related domain
Pan110_RS06755	COG3795	YCII-related domain
Pan110_RS06770	COG1764	response to oxidative stress
Pan110_RS06795	COG2755	lipolytic protein G-D-S-L family
Pan110_RS06795	COG0657	acetylesterase activity
Pan110_RS06800	COG0667	Aldo Keto reductase
Pan110_RS06830	COG3608	succinylglutamate desuccinylase aspartoacylase
Pan110_RS06835	COG4948	Mandelate Racemase Muconate Lactonizing
Pan110_RS06855	COG0463	Glycosyl transferase, family 2
Pan110_RS06860	COG0515	serine threonine protein kinase
Pan110_RS06875	COG1609	Transcriptional regulator
Pan110_RS06875	COG2207	Transcriptional regulator
Pan110_RS06885	COG0693	protein deglycase activity
Pan110_RS06895	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Pan110_RS06895	COG0662	Cupin 2, conserved barrel domain protein
Pan110_RS06910	COG1215	transferase activity, transferring glycosyl groups
Pan110_RS06915	COG3769	mannosylglycerate metabolic process
Pan110_RS06960	COG4191	Histidine kinase
Pan110_RS06965	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Pan110_RS07010	COG1131	(ABC) transporter
Pan110_RS07020	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Pan110_RS07025	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Pan110_RS07065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Pan110_RS07070	COG0069	glutamate synthase activity
Pan110_RS07075	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Pan110_RS07100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Pan110_RS07100	COG2010	Cytochrome c
Pan110_RS07115	COG2217	Heavy metal translocating P-type atpase
Pan110_RS07125	COG1858	cytochrome C peroxidase
Pan110_RS07130	COG1132	(ABC) transporter
Pan110_RS07155	COG2755	lipolytic protein G-D-S-L family
Pan110_RS07155	COG0657	acetylesterase activity
Pan110_RS07195	COG2186	Transcriptional regulator
Pan110_RS07200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Pan110_RS07215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Pan110_RS07215	COG0784	Response regulator, receiver
Pan110_RS07215	COG2198	Histidine kinase
Pan110_RS07215	COG2205	protein histidine kinase activity
Pan110_RS07290	COG1012	belongs to the aldehyde dehydrogenase family
Pan110_RS07335	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Pan110_RS07340	COG0072	phenylalanine-tRNA ligase activity
Pan110_RS07355	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Pan110_RS07390	COG3119	arylsulfatase activity
Pan110_RS07400	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Pan110_RS07415	COG2815	serine threonine protein kinase
Pan110_RS07415	COG0515	serine threonine protein kinase
Pan110_RS07420	COG0515	serine threonine protein kinase
Pan110_RS07425	COG2815	serine threonine protein kinase
Pan110_RS07425	COG0515	serine threonine protein kinase
Pan110_RS07455	COG3383	formate dehydrogenase (NAD+) activity
Pan110_RS07515	COG3237	CsbD-like
Pan110_RS07530	COG2204	response regulator
Pan110_RS07535	COG5487	UPF0391 membrane protein
Pan110_RS07590	COG0714	Associated with various cellular activities
Pan110_RS07600	COG4537	Required for transformation and DNA binding
Pan110_RS07630	COG2226	methyltransferase
Pan110_RS07640	COG3328	transposase activity
Pan110_RS07675	COG3852	Histidine kinase
Pan110_RS07680	COG2204	response regulator
Pan110_RS07710	COG1028	Short-chain dehydrogenase reductase Sdr
Pan110_RS07735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Pan110_RS07760	COG0673	inositol 2-dehydrogenase activity
Pan110_RS07780	COG1368	sulfuric ester hydrolase activity
Pan110_RS07785	COG1028	Short-chain dehydrogenase reductase Sdr
Pan110_RS07795	COG1404	Belongs to the peptidase S8 family
Pan110_RS07835	COG2204	response regulator
Pan110_RS07855	COG3119	arylsulfatase activity
Pan110_RS07860	COG3119	arylsulfatase activity
Pan110_RS07865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS07920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Pan110_RS07925	COG0463	Glycosyl transferase, family 2
Pan110_RS07945	COG0400	carboxylic ester hydrolase activity
Pan110_RS07970	COG0584	glycerophosphoryl diester phosphodiesterase
Pan110_RS07995	COG0392	lysyltransferase activity
Pan110_RS08030	COG4067	protein conserved in archaea
Pan110_RS08030	COG0189	ligase activity
Pan110_RS08035	COG0189	ligase activity
Pan110_RS08035	COG0569	domain protein
Pan110_RS08080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Pan110_RS08080	COG3153	acetyltransferase
Pan110_RS08085	COG0598	Magnesium transport protein CorA
Pan110_RS08090	COG3385	transposase activity
Pan110_RS08200	COG0367	asparagine synthase
Pan110_RS08215	COG1083	cytidylyl-transferase
Pan110_RS08220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Pan110_RS08230	COG2089	acid synthase
Pan110_RS08235	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Pan110_RS08245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Pan110_RS08250	COG0728	peptidoglycan biosynthetic process
Pan110_RS08260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Pan110_RS08270	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Pan110_RS08285	COG2226	methyltransferase
Pan110_RS08305	COG2814	Major facilitator Superfamily
Pan110_RS08315	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Pan110_RS08325	COG0037	tRNA processing
Pan110_RS08330	COG1418	mRNA catabolic process
Pan110_RS08335	COG2808	Putative FMN-binding domain
Pan110_RS08360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Pan110_RS08380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Pan110_RS08390	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Pan110_RS08395	COG0784	Response regulator, receiver
Pan110_RS08395	COG2205	protein histidine kinase activity
Pan110_RS08395	COG5002	protein histidine kinase activity
Pan110_RS08415	COG0460	homoserine dehydrogenase
Pan110_RS08415	COG0527	aspartate kinase activity
Pan110_RS08500	COG0753	catalase activity
Pan110_RS08505	COG0583	DNA-binding transcription factor activity
Pan110_RS08540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Pan110_RS08600	COG0531	amino acid
Pan110_RS08650	COG2815	serine threonine protein kinase
Pan110_RS08650	COG0515	serine threonine protein kinase
Pan110_RS08800	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Pan110_RS08810	COG5000	phosphorelay sensor kinase activity
Pan110_RS08810	COG5002	protein histidine kinase activity
Pan110_RS08815	COG0745	RESPONSE REGULATOR receiver
Pan110_RS08845	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Pan110_RS08880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Pan110_RS08880	COG1017	nitric oxide dioxygenase activity
Pan110_RS08900	COG1959	2 iron, 2 sulfur cluster binding
Pan110_RS08930	COG2815	serine threonine protein kinase
Pan110_RS08930	COG0515	serine threonine protein kinase
Pan110_RS08945	COG0714	Associated with various cellular activities
Pan110_RS08960	COG4335	DNA alkylation repair
Pan110_RS08970	COG2815	serine threonine protein kinase
Pan110_RS08970	COG0515	serine threonine protein kinase
Pan110_RS09020	COG0714	Associated with various cellular activities
Pan110_RS09055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Pan110_RS09095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Pan110_RS09100	COG3002	Belongs to the UPF0753 family
Pan110_RS09110	COG1132	(ABC) transporter
Pan110_RS09160	COG2814	Major facilitator Superfamily
Pan110_RS09240	COG0515	serine threonine protein kinase
Pan110_RS09240	COG2815	serine threonine protein kinase
Pan110_RS09280	COG0584	glycerophosphoryl diester phosphodiesterase
Pan110_RS09350	COG3119	arylsulfatase activity
Pan110_RS09385	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Pan110_RS09410	COG2204	response regulator
Pan110_RS09445	COG0714	Associated with various cellular activities
Pan110_RS09485	COG0515	serine threonine protein kinase
Pan110_RS09485	COG0457	Tetratricopeptide repeat
Pan110_RS09540	COG1073	alpha beta
Pan110_RS09580	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Pan110_RS09585	COG3409	Peptidoglycan-binding domain 1 protein
Pan110_RS09585	COG0793	Belongs to the peptidase S41A family
Pan110_RS09595	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Pan110_RS09600	COG1074	ATP-dependent DNA helicase activity
Pan110_RS09615	COG0673	inositol 2-dehydrogenase activity
Pan110_RS09620	COG1301	dicarboxylic acid transport
Pan110_RS09625	COG2208	phosphoserine phosphatase activity
Pan110_RS09645	COG2218	PFAM glutamate synthase alpha subunit domain protein
Pan110_RS09650	COG0318	PFAM AMP-dependent synthetase and ligase
Pan110_RS09655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Pan110_RS09660	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Pan110_RS09685	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Pan110_RS09690	COG0653	protein targeting
Pan110_RS09695	COG1519	Transferase
Pan110_RS09700	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Pan110_RS09710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Pan110_RS09740	COG0525	valine-tRNA ligase activity
Pan110_RS09745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Pan110_RS09755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Pan110_RS09760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Pan110_RS09765	COG1758	RNA polymerase activity
Pan110_RS09770	COG0194	GDP metabolic process
Pan110_RS09775	COG1561	YicC-like family, N-terminal region
Pan110_RS09785	COG0149	triose-phosphate isomerase activity
Pan110_RS09790	COG0077	Prephenate dehydratase
Pan110_RS09790	COG1605	Chorismate mutase
Pan110_RS09795	COG0443	Heat shock 70 kDa protein
Pan110_RS09800	COG0542	response to heat
Pan110_RS09810	COG0673	inositol 2-dehydrogenase activity
Pan110_RS09815	COG0617	tRNA 3'-terminal CCA addition
Pan110_RS09840	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Pan110_RS09855	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Pan110_RS09870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Pan110_RS09880	COG2001	Belongs to the MraZ family
Pan110_RS09885	COG0275	rRNA processing
Pan110_RS09915	COG2204	response regulator
Pan110_RS09925	COG1558	bacterial-type flagellum-dependent cell motility
Pan110_RS09930	COG1677	Flagellar hook-basal body complex protein FliE
Pan110_RS09940	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Pan110_RS09945	COG1317	bacterial-type flagellum organization
Pan110_RS09950	COG1157	protein secretion by the type III secretion system
Pan110_RS09970	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Pan110_RS09975	COG1749	Flagellar hook protein flgE
Pan110_RS09980	COG1582	Flagellar protein (FlbD)
Pan110_RS09990	COG1360	Flagellar Motor Protein
Pan110_RS10015	COG1987	bacterial-type flagellum assembly
Pan110_RS10020	COG1684	flagellar biosynthetic protein fliR
Pan110_RS10025	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Pan110_RS10035	COG3852	Histidine kinase
Pan110_RS10045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Pan110_RS10060	COG3458	cephalosporin-C deacetylase activity
Pan110_RS10080	COG4964	Belongs to the GSP D family
Pan110_RS10100	COG1482	cell wall glycoprotein biosynthetic process
Pan110_RS10110	COG0347	Belongs to the P(II) protein family
Pan110_RS10115	COG0347	Belongs to the P(II) protein family
Pan110_RS10120	COG0004	ammonium transporteR
Pan110_RS10125	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Pan110_RS10130	COG0735	belongs to the Fur family
Pan110_RS10135	COG2747	anti-sigma28 factor FlgM
Pan110_RS10145	COG1606	tRNA processing
Pan110_RS10160	COG1490	D-aminoacyl-tRNA deacylase activity
Pan110_RS10170	COG0825	malonyl-CoA metabolic process
Pan110_RS10175	COG2815	serine threonine protein kinase
Pan110_RS10175	COG0515	serine threonine protein kinase
Pan110_RS10195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Pan110_RS10200	COG0745	RESPONSE REGULATOR receiver
Pan110_RS10220	COG4948	Mandelate Racemase Muconate Lactonizing
Pan110_RS10245	COG3385	transposase activity
Pan110_RS10250	COG1609	Transcriptional regulator
Pan110_RS10260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Pan110_RS10270	COG1129	ABC transporter
Pan110_RS10275	COG1172	Belongs to the binding-protein-dependent transport system permease family
Pan110_RS10315	COG1335	isochorismatase
Pan110_RS10330	COG2226	methyltransferase
Pan110_RS10395	COG2267	carboxylic ester hydrolase activity
Pan110_RS10470	COG3415	Transposase
Pan110_RS10470	COG2801	Transposase and inactivated derivatives
Pan110_RS10480	COG1802	Transcriptional regulator
Pan110_RS10500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Pan110_RS10500	COG2755	lipolytic protein G-D-S-L family
Pan110_RS10515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Pan110_RS10530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Pan110_RS10535	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Pan110_RS10540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Pan110_RS10545	COG4948	Mandelate Racemase Muconate Lactonizing
Pan110_RS10555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Pan110_RS10560	COG2271	Major facilitator Superfamily
Pan110_RS10565	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Pan110_RS10570	COG0363	glucosamine-6-phosphate deaminase activity
Pan110_RS10585	COG0019	diaminopimelate decarboxylase activity
Pan110_RS10590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Pan110_RS10595	COG0151	Belongs to the GarS family
Pan110_RS10600	COG2045	Belongs to the ComB family
Pan110_RS10605	COG0423	glycine-tRNA ligase activity
Pan110_RS10635	COG3119	arylsulfatase activity
Pan110_RS10640	COG1063	alcohol dehydrogenase
Pan110_RS10660	COG1011	Hydrolase
Pan110_RS10720	COG2204	response regulator
Pan110_RS10740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS10775	COG3119	arylsulfatase activity
Pan110_RS10780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Pan110_RS10790	COG0667	Aldo Keto reductase
Pan110_RS10800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Pan110_RS10805	COG1234	tRNA 3'-trailer cleavage
Pan110_RS10810	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Pan110_RS10820	COG0205	6-phosphofructokinase activity
Pan110_RS10835	COG4948	Mandelate Racemase Muconate Lactonizing
Pan110_RS10850	COG2706	6-phosphogluconolactonase activity
Pan110_RS10870	COG1073	alpha beta
Pan110_RS10880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Pan110_RS10885	COG0247	lactate metabolic process
Pan110_RS10890	COG0277	FAD linked oxidase domain protein
Pan110_RS10895	COG0277	FAD linked oxidase domain protein
Pan110_RS10905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Pan110_RS10915	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Pan110_RS10930	COG3119	arylsulfatase activity
Pan110_RS10935	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Pan110_RS10945	COG0512	Glutamine amidotransferase of anthranilate synthase
Pan110_RS10950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Pan110_RS10960	COG2154	pterin-4-alpha-carbinolamine dehydratase
Pan110_RS11000	COG4974	Belongs to the 'phage' integrase family
Pan110_RS11025	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Pan110_RS11035	COG1702	phosphate starvation-inducible protein PhoH
Pan110_RS11050	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Pan110_RS11050	COG0321	lipoyl(octanoyl) transferase activity
Pan110_RS11060	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Pan110_RS11075	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Pan110_RS11085	COG3119	arylsulfatase activity
Pan110_RS11150	COG0562	UDP-galactopyranose mutase
Pan110_RS11160	COG3119	arylsulfatase activity
Pan110_RS11195	COG0574	Belongs to the PEP-utilizing enzyme family
Pan110_RS11195	COG3848	Pyruvate phosphate dikinase
Pan110_RS11240	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Pan110_RS11250	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Pan110_RS11260	COG3328	transposase activity
Pan110_RS11270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Pan110_RS11290	COG1216	Glycosyl transferase, family 2
Pan110_RS11295	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Pan110_RS11305	COG0492	ferredoxin-NADP+ reductase activity
Pan110_RS11320	COG0596	Alpha beta hydrolase
Pan110_RS11325	COG0513	Belongs to the DEAD box helicase family
Pan110_RS11330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Pan110_RS11335	COG0463	Glycosyl transferase, family 2
Pan110_RS11345	COG0539	negative regulation of cytoplasmic translation
Pan110_RS11345	COG2183	response to ionizing radiation
Pan110_RS11350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Pan110_RS11380	COG0714	Associated with various cellular activities
Pan110_RS11400	COG1657	PFAM Prenyltransferase squalene oxidase
Pan110_RS11405	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Pan110_RS11440	COG0802	atpase or kinase
Pan110_RS11450	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Pan110_RS11455	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Pan110_RS11460	COG0556	nucleotide-excision repair
Pan110_RS11465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Pan110_RS11470	COG0456	acetyltransferase
Pan110_RS11495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Pan110_RS11500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Pan110_RS11505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Pan110_RS11510	COG0772	Belongs to the SEDS family
Pan110_RS11515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Pan110_RS11540	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Pan110_RS11565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Pan110_RS11590	COG0463	Glycosyl transferase, family 2
Pan110_RS11630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Pan110_RS11655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Pan110_RS11660	COG0540	Belongs to the ATCase OTCase family
Pan110_RS11695	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Pan110_RS11700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Pan110_RS11700	COG0515	serine threonine protein kinase
Pan110_RS11710	COG0745	RESPONSE REGULATOR receiver
Pan110_RS11730	COG1994	Peptidase M50
Pan110_RS11735	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Pan110_RS11745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Pan110_RS11760	COG0124	histidyl-tRNA synthetase
Pan110_RS11780	COG1595	DNA-templated transcription, initiation
Pan110_RS11785	COG0515	serine threonine protein kinase
Pan110_RS11785	COG2815	serine threonine protein kinase
Pan110_RS11800	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Pan110_RS11810	COG0343	queuine tRNA-ribosyltransferase activity
Pan110_RS11815	COG1862	Preprotein translocase
Pan110_RS11820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Pan110_RS11830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Pan110_RS11855	COG0515	serine threonine protein kinase
Pan110_RS11855	COG2815	serine threonine protein kinase
Pan110_RS11860	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Pan110_RS11870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Pan110_RS11880	COG0643	Histidine kinase
Pan110_RS11880	COG2198	Histidine kinase
Pan110_RS11880	COG0784	Response regulator, receiver
Pan110_RS11895	COG0745	RESPONSE REGULATOR receiver
Pan110_RS11900	COG2201	protein-glutamate methylesterase activity
Pan110_RS11905	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Pan110_RS11910	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Pan110_RS11920	COG0222	ribosome binding
Pan110_RS11945	COG1136	(ABC) transporter
Pan110_RS11945	COG0577	efflux transmembrane transporter activity
Pan110_RS11955	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Pan110_RS11960	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Pan110_RS11970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Pan110_RS11995	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Pan110_RS12080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Pan110_RS12130	COG0438	transferase activity, transferring glycosyl groups
Pan110_RS12135	COG2204	response regulator
Pan110_RS12165	COG0189	ligase activity
Pan110_RS12165	COG4067	protein conserved in archaea
Pan110_RS12170	COG0456	acetyltransferase
Pan110_RS12220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Pan110_RS12290	COG3328	transposase activity
Pan110_RS12330	COG2195	Cleaves the N-terminal amino acid of tripeptides
Pan110_RS12335	COG0793	Belongs to the peptidase S41A family
Pan110_RS12345	COG0515	serine threonine protein kinase
Pan110_RS12345	COG2815	serine threonine protein kinase
Pan110_RS12350	COG3852	Histidine kinase
Pan110_RS12365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Pan110_RS12380	COG0390	transport system, permease component
Pan110_RS12410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Pan110_RS12415	COG1105	Belongs to the carbohydrate kinase PfkB family
Pan110_RS12430	COG0386	Belongs to the glutathione peroxidase family
Pan110_RS12530	COG0612	Peptidase, M16
Pan110_RS12535	COG0612	Peptidase, M16
Pan110_RS12540	COG4948	Mandelate Racemase Muconate Lactonizing
Pan110_RS12575	COG0642	Histidine kinase
Pan110_RS12580	COG0745	RESPONSE REGULATOR receiver
Pan110_RS12590	COG3119	arylsulfatase activity
Pan110_RS12595	COG0154	amidase activity
Pan110_RS12600	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Pan110_RS12605	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Pan110_RS12610	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Pan110_RS12615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Pan110_RS12620	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Pan110_RS12625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS12645	COG1283	sodium-dependent phosphate transmembrane transporter activity
Pan110_RS12715	COG3384	dioxygenase
Pan110_RS12720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Pan110_RS12730	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Pan110_RS12735	COG3119	arylsulfatase activity
Pan110_RS12740	COG2912	Transglutaminase-like superfamily
Pan110_RS12750	COG0705	Rhomboid family
Pan110_RS12755	COG0612	Peptidase, M16
Pan110_RS12790	COG4796	Type ii and iii secretion system protein
Pan110_RS12810	COG0285	dihydrofolate synthase activity
Pan110_RS12835	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Pan110_RS12845	COG2204	response regulator
Pan110_RS12850	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Pan110_RS12855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS12855	COG0706	membrane insertase activity
Pan110_RS12860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Pan110_RS12865	COG0471	metal ion transport
Pan110_RS12935	COG2076	Multidrug Resistance protein
Pan110_RS12970	COG0463	Glycosyl transferase, family 2
Pan110_RS12975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Pan110_RS13040	COG3153	acetyltransferase
Pan110_RS13065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Pan110_RS13070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Pan110_RS13070	COG2207	Transcriptional regulator
Pan110_RS13160	COG4106	trans-aconitate 2-methyltransferase activity
Pan110_RS13170	COG0243	molybdopterin cofactor binding
Pan110_RS13200	COG1899	peptidyl-lysine modification to peptidyl-hypusine
Pan110_RS13205	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Pan110_RS13240	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Pan110_RS13245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Pan110_RS13295	COG0714	Associated with various cellular activities
Pan110_RS13345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Pan110_RS13355	COG0367	asparagine synthase
Pan110_RS13360	COG0438	transferase activity, transferring glycosyl groups
Pan110_RS13365	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Pan110_RS13390	COG3253	May function as heme-dependent peroxidase
Pan110_RS13395	COG1073	alpha beta
Pan110_RS13400	COG0542	response to heat
Pan110_RS13410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Pan110_RS13420	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Pan110_RS13510	COG1802	Transcriptional regulator
Pan110_RS13550	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Pan110_RS13560	COG1082	Xylose isomerase domain protein TIM barrel
Pan110_RS13585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Pan110_RS13610	COG1446	asparaginase
Pan110_RS13620	COG1473	amidohydrolase
Pan110_RS13630	COG0531	amino acid
Pan110_RS13645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Pan110_RS13650	COG0204	Acyl-transferase
Pan110_RS13720	COG2433	Pfam Transposase IS66
Pan110_RS13725	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Pan110_RS13735	COG3328	transposase activity
Pan110_RS13775	COG3328	transposase activity
Pan110_RS13785	COG3328	transposase activity
Pan110_RS13845	COG2217	Heavy metal translocating P-type atpase
Pan110_RS13860	COG0348	domain, Protein
Pan110_RS13865	COG2010	Cytochrome c
Pan110_RS13870	COG3278	Belongs to the heme-copper respiratory oxidase family
Pan110_RS13915	COG1595	DNA-templated transcription, initiation
Pan110_RS13925	COG0243	molybdopterin cofactor binding
Pan110_RS13930	COG0437	4 iron, 4 sulfur cluster binding
Pan110_RS13935	COG1017	nitric oxide dioxygenase activity
Pan110_RS13935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Pan110_RS13940	COG2146	nitrite reductase [NAD(P)H] activity
Pan110_RS13940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Pan110_RS13950	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Pan110_RS13955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Pan110_RS13960	COG1858	cytochrome C peroxidase
Pan110_RS13970	COG0515	serine threonine protein kinase
Pan110_RS13970	COG2815	serine threonine protein kinase
Pan110_RS13980	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Pan110_RS13990	COG0205	6-phosphofructokinase activity
Pan110_RS14020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Pan110_RS14025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Pan110_RS14030	COG2084	Dehydrogenase
Pan110_RS14045	COG3963	phosphatidate phosphatase activity
Pan110_RS14075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Pan110_RS14080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Pan110_RS14085	COG1509	lysine 2,3-aminomutase activity
Pan110_RS14090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Pan110_RS14100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Pan110_RS14115	COG3119	arylsulfatase activity
Pan110_RS14125	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Pan110_RS14140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Pan110_RS14145	COG0601	transmembrane transport
Pan110_RS14150	COG4166	transmembrane transport
Pan110_RS14160	COG4172	Belongs to the ABC transporter superfamily
Pan110_RS14170	COG2333	competence protein COMEC
Pan110_RS14170	COG0658	competence protein
Pan110_RS14190	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Pan110_RS14205	COG0473	3-isopropylmalate dehydrogenase activity
Pan110_RS14210	COG3622	Belongs to the hyi family
Pan110_RS14255	COG0714	Associated with various cellular activities
Pan110_RS14265	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Pan110_RS14295	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Pan110_RS14300	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Pan110_RS14300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Pan110_RS14305	COG0440	acetolactate synthase activity
Pan110_RS14310	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Pan110_RS14335	COG0356	it plays a direct role in the translocation of protons across the membrane
Pan110_RS14340	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Pan110_RS14355	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Pan110_RS14360	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Pan110_RS14365	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Pan110_RS14370	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Pan110_RS14390	COG0590	tRNA wobble adenosine to inosine editing
Pan110_RS14415	COG3328	transposase activity
Pan110_RS14440	COG4948	Mandelate Racemase Muconate Lactonizing
Pan110_RS14485	COG3258	Cytochrome c
Pan110_RS14550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Pan110_RS14555	COG3938	Belongs to the proline racemase family
Pan110_RS14570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Pan110_RS14575	COG0045	succinate-CoA ligase (ADP-forming) activity
Pan110_RS14575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Pan110_RS14575	COG1042	CoA-binding domain protein
Pan110_RS14710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Pan110_RS14715	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Pan110_RS14725	COG1012	belongs to the aldehyde dehydrogenase family
Pan110_RS14730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Pan110_RS14740	COG0792	nuclease activity
Pan110_RS14745	COG0335	large ribosomal subunit rRNA binding
Pan110_RS14750	COG0336	Belongs to the RNA methyltransferase TrmD family
Pan110_RS14755	COG0228	four-way junction DNA binding
Pan110_RS14760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Pan110_RS14765	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Pan110_RS14770	COG0066	3-isopropylmalate dehydratase activity
Pan110_RS14885	COG3119	arylsulfatase activity
Pan110_RS14895	COG3119	arylsulfatase activity
Pan110_RS14905	COG3408	Glycogen debranching enzyme
Pan110_RS14905	COG3119	arylsulfatase activity
Pan110_RS14915	COG3119	arylsulfatase activity
Pan110_RS14925	COG5002	protein histidine kinase activity
Pan110_RS14925	COG2205	protein histidine kinase activity
Pan110_RS14925	COG0784	Response regulator, receiver
Pan110_RS14985	COG1802	Transcriptional regulator
Pan110_RS15025	COG0024	Methionine aminopeptidase
Pan110_RS15050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Pan110_RS15065	COG0488	(ABC) transporter
Pan110_RS15080	COG3119	arylsulfatase activity
Pan110_RS15090	COG0488	(ABC) transporter
Pan110_RS15110	COG0438	transferase activity, transferring glycosyl groups
Pan110_RS15135	COG1045	serine acetyltransferase
Pan110_RS15165	COG5002	protein histidine kinase activity
Pan110_RS15235	COG2815	serine threonine protein kinase
Pan110_RS15235	COG0515	serine threonine protein kinase
Pan110_RS15300	COG0673	inositol 2-dehydrogenase activity
Pan110_RS15310	COG3119	arylsulfatase activity
Pan110_RS15405	COG1136	(ABC) transporter
Pan110_RS15410	COG0577	efflux transmembrane transporter activity
Pan110_RS15410	COG1136	(ABC) transporter
Pan110_RS15420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Pan110_RS15455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Pan110_RS15465	COG2204	response regulator
Pan110_RS15470	COG3852	Histidine kinase
Pan110_RS15475	COG1185	polyribonucleotide nucleotidyltransferase activity
Pan110_RS15480	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Pan110_RS15490	COG1201	RNA secondary structure unwinding
Pan110_RS15515	COG0811	peptide transport
Pan110_RS15550	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Pan110_RS15560	COG0326	Molecular chaperone. Has ATPase activity
Pan110_RS15650	COG2433	Pfam Transposase IS66
Pan110_RS15690	COG3119	arylsulfatase activity
Pan110_RS15715	COG1012	belongs to the aldehyde dehydrogenase family
Pan110_RS15810	COG1414	Transcriptional regulator
Pan110_RS15845	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Pan110_RS15845	COG3264	Mechanosensitive ion channel
Pan110_RS15905	COG0148	phosphopyruvate hydratase activity
Pan110_RS15950	COG1070	Carbohydrate kinase
Pan110_RS15955	COG0552	protein localization to endoplasmic reticulum
Pan110_RS15970	COG0138	bifunctional purine biosynthesis protein purh
Pan110_RS15985	COG0457	Tetratricopeptide repeat
Pan110_RS15990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Pan110_RS16030	COG0497	DNA recombination
Pan110_RS16035	COG2706	6-phosphogluconolactonase activity
Pan110_RS16040	COG0135	phosphoribosylanthranilate isomerase activity
Pan110_RS16045	COG0745	RESPONSE REGULATOR receiver
Pan110_RS16055	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Pan110_RS16060	COG0504	CTP synthase activity
Pan110_RS16065	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Pan110_RS16070	COG0424	maF-like protein
Pan110_RS16105	COG0673	inositol 2-dehydrogenase activity
Pan110_RS16115	COG3119	arylsulfatase activity
Pan110_RS16135	COG2046	Belongs to the sulfate adenylyltransferase family
Pan110_RS16150	COG0268	Binds directly to 16S ribosomal RNA
Pan110_RS16165	COG2211	Major facilitator Superfamily
Pan110_RS16175	COG0071	Belongs to the small heat shock protein (HSP20) family
Pan110_RS16225	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Pan110_RS16230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Pan110_RS16235	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Pan110_RS16250	COG2373	Large extracellular alpha-helical protein
Pan110_RS16255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Pan110_RS16265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Pan110_RS16280	COG1573	uracil-dna glycosylase
Pan110_RS16310	COG3119	arylsulfatase activity
Pan110_RS16325	COG0673	inositol 2-dehydrogenase activity
Pan110_RS16335	COG2207	Transcriptional regulator
Pan110_RS16335	COG1609	Transcriptional regulator
Pan110_RS16340	COG0456	acetyltransferase
Pan110_RS16340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Pan110_RS16345	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Pan110_RS16355	COG0515	serine threonine protein kinase
Pan110_RS16355	COG2815	serine threonine protein kinase
Pan110_RS16370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Pan110_RS16395	COG0705	Rhomboid family
Pan110_RS16425	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Pan110_RS16430	COG2890	protein-(glutamine-N5) methyltransferase activity
Pan110_RS16435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Pan110_RS16440	COG0254	rRNA binding
Pan110_RS16450	COG4284	Utp--glucose-1-phosphate uridylyltransferase
Pan110_RS16460	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Pan110_RS16480	COG0528	UMP kinase activity
Pan110_RS16485	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Pan110_RS16490	COG0052	Belongs to the universal ribosomal protein uS2 family
Pan110_RS16495	COG1160	GTP binding
Pan110_RS16510	COG1968	undecaprenyl-diphosphatase activity
Pan110_RS16535	COG1555	photosystem II stabilization
Pan110_RS16545	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Pan110_RS16555	COG3781	membrane
Pan110_RS16570	COG3119	arylsulfatase activity
Pan110_RS16585	COG3119	arylsulfatase activity
Pan110_RS16640	COG2204	response regulator
Pan110_RS16645	COG3852	Histidine kinase
Pan110_RS16650	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Pan110_RS16670	COG3119	arylsulfatase activity
Pan110_RS16705	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Pan110_RS16710	COG2326	polyphosphate kinase activity
Pan110_RS16720	COG2721	sulfolactate sulfo-lyase activity
Pan110_RS16750	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Pan110_RS16760	COG2815	serine threonine protein kinase
Pan110_RS16760	COG0515	serine threonine protein kinase
Pan110_RS16770	COG0543	2 iron, 2 sulfur cluster binding
Pan110_RS16775	COG1187	pseudouridine synthase activity
Pan110_RS16780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Pan110_RS16790	COG0508	dehydrogenase complex catalyzes the overall conversion of
Pan110_RS16795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Pan110_RS16805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Pan110_RS16820	COG0101	tRNA pseudouridine synthase activity
Pan110_RS16825	COG0165	Argininosuccinate lyase
Pan110_RS16840	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Pan110_RS16845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Pan110_RS16850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Pan110_RS16865	COG1295	ribonuclease BN
Pan110_RS16890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Pan110_RS16910	COG4191	Histidine kinase
Pan110_RS16915	COG2205	protein histidine kinase activity
Pan110_RS16915	COG0784	Response regulator, receiver
Pan110_RS16920	COG4566	intracellular signal transduction
Pan110_RS16950	COG3119	arylsulfatase activity
Pan110_RS16965	COG1028	Short-chain dehydrogenase reductase Sdr
Pan110_RS16970	COG1250	3-hydroxyacyl-CoA dehydrogenase
Pan110_RS16980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Pan110_RS16985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS17020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Pan110_RS17040	COG0488	(ABC) transporter
Pan110_RS17070	COG0544	peptidyl-prolyl cis-trans isomerase activity
Pan110_RS17085	COG1217	gtp-binding protein TYPA
Pan110_RS17090	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Pan110_RS17100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS17105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS17115	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Pan110_RS17145	COG3850	Histidine kinase
Pan110_RS17145	COG4999	Histidine kinase
Pan110_RS17145	COG3437	response regulator, receiver
Pan110_RS17145	COG2205	protein histidine kinase activity
Pan110_RS17155	COG2832	Protein of unknown function (DUF454)
Pan110_RS17190	COG0047	phosphoribosylformylglycinamidine synthase activity
Pan110_RS17205	COG0673	inositol 2-dehydrogenase activity
Pan110_RS17225	COG1368	sulfuric ester hydrolase activity
Pan110_RS17325	COG0546	phosphoglycolate phosphatase activity
Pan110_RS17360	COG0584	glycerophosphoryl diester phosphodiesterase
Pan110_RS17395	COG3119	arylsulfatase activity
Pan110_RS17435	COG0584	glycerophosphoryl diester phosphodiesterase
Pan110_RS17440	COG0596	Alpha beta hydrolase
Pan110_RS17515	COG5441	Belongs to the UPF0261 family
Pan110_RS17520	COG5564	TIM-barrel signal transduction protein
Pan110_RS17535	COG3119	arylsulfatase activity
Pan110_RS17545	COG3119	arylsulfatase activity
Pan110_RS17565	COG0515	serine threonine protein kinase
Pan110_RS17565	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Pan110_RS17595	COG3119	arylsulfatase activity
Pan110_RS17610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Pan110_RS17675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Pan110_RS17750	COG0501	Belongs to the peptidase M48B family
Pan110_RS17755	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Pan110_RS17850	COG3030	protein affecting phage T7 exclusion by the F plasmid
Pan110_RS17870	COG1233	COG1233 Phytoene dehydrogenase and related
Pan110_RS17875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Pan110_RS17880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Pan110_RS17905	COG4977	sequence-specific DNA binding
Pan110_RS17940	COG1129	ABC transporter
Pan110_RS17945	COG1172	Belongs to the binding-protein-dependent transport system permease family
Pan110_RS17955	COG1229	Formylmethanofuran dehydrogenase subunit A
Pan110_RS17960	COG0288	reversible hydration of carbon dioxide
Pan110_RS17970	COG3002	Belongs to the UPF0753 family
Pan110_RS17975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Pan110_RS17980	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Pan110_RS17985	COG0521	Mo-molybdopterin cofactor biosynthetic process
Pan110_RS18010	COG1136	(ABC) transporter
Pan110_RS18030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Pan110_RS18040	COG1136	(ABC) transporter
Pan110_RS18050	COG0484	heat shock protein binding
Pan110_RS18060	COG0594	ribonuclease P activity
Pan110_RS18065	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Pan110_RS18075	COG0589	response to stress
Pan110_RS18100	COG4948	Mandelate Racemase Muconate Lactonizing
Pan110_RS18115	COG3706	GGDEF domain
Pan110_RS18130	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Pan110_RS18140	COG3119	arylsulfatase activity
Pan110_RS18155	COG0574	Belongs to the PEP-utilizing enzyme family
Pan110_RS18155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Pan110_RS18160	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Pan110_RS18190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Pan110_RS18200	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Pan110_RS18205	COG0617	tRNA 3'-terminal CCA addition
Pan110_RS18205	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Pan110_RS18205	COG0517	IMP dehydrogenase activity
Pan110_RS18210	COG0309	Hydrogenase expression formation protein (HypE)
Pan110_RS18220	COG0298	carbon dioxide binding
Pan110_RS18225	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Pan110_RS18235	COG0375	protein maturation
Pan110_RS18245	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Pan110_RS18280	COG2197	response regulator
Pan110_RS18285	COG0071	Belongs to the small heat shock protein (HSP20) family
Pan110_RS18295	COG2239	Acts as a magnesium transporter
Pan110_RS18300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Pan110_RS18305	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
Pan110_RS18315	COG1473	amidohydrolase
Pan110_RS18355	COG1012	belongs to the aldehyde dehydrogenase family
Pan110_RS18370	COG3328	transposase activity
Pan110_RS18425	COG0515	serine threonine protein kinase
Pan110_RS18435	COG1199	ATP-dependent helicase activity
Pan110_RS18440	COG2208	phosphoserine phosphatase activity
Pan110_RS18445	COG0515	serine threonine protein kinase
Pan110_RS18445	COG2815	serine threonine protein kinase
Pan110_RS18450	COG0436	Aminotransferase
Pan110_RS18455	COG0494	nUDIX hydrolase
Pan110_RS18470	COG1573	uracil-dna glycosylase
Pan110_RS18475	COG0788	formyltetrahydrofolate deformylase activity
Pan110_RS18540	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Pan110_RS18545	COG4191	Histidine kinase
Pan110_RS18555	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
Pan110_RS18580	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Pan110_RS18620	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Pan110_RS18630	COG3119	arylsulfatase activity
Pan110_RS18635	COG1505	serine-type exopeptidase activity
Pan110_RS18650	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Pan110_RS18650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Pan110_RS18655	COG0237	dephospho-CoA kinase activity
Pan110_RS18660	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Pan110_RS18670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Pan110_RS18695	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Pan110_RS18700	COG3119	arylsulfatase activity
Pan110_RS18705	COG3119	arylsulfatase activity
Pan110_RS18715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Pan110_RS18720	COG1132	(ABC) transporter
Pan110_RS18735	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Pan110_RS18755	COG0673	inositol 2-dehydrogenase activity
Pan110_RS18760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Pan110_RS18765	COG3119	arylsulfatase activity
Pan110_RS18770	COG1668	transmembrane transport
Pan110_RS18775	COG4555	ABC transporter
Pan110_RS18795	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Pan110_RS18795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Pan110_RS18825	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Pan110_RS18830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Pan110_RS18835	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Pan110_RS18840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Pan110_RS18875	COG0167	dihydroorotate dehydrogenase activity
Pan110_RS18880	COG0180	Tryptophanyl-tRNA synthetase
Pan110_RS18905	COG0175	sulfate reduction
Pan110_RS18915	COG0071	Belongs to the small heat shock protein (HSP20) family
Pan110_RS18920	COG0174	glutamine synthetase
Pan110_RS18925	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Pan110_RS18975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Pan110_RS18995	COG0848	biopolymer transport protein
Pan110_RS19000	COG0084	hydrolase, TatD family'
Pan110_RS19045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Pan110_RS19055	COG0456	acetyltransferase
Pan110_RS19060	COG0673	inositol 2-dehydrogenase activity
Pan110_RS19065	COG0515	serine threonine protein kinase
Pan110_RS19065	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Pan110_RS19075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Pan110_RS19245	COG3706	GGDEF domain
Pan110_RS19260	COG0653	protein targeting
Pan110_RS19310	COG1278	Cold shock
Pan110_RS19325	COG1309	transcriptional regulator
Pan110_RS19330	COG3119	arylsulfatase activity
Pan110_RS19340	COG0598	Magnesium transport protein CorA
Pan110_RS19410	COG0714	Associated with various cellular activities
Pan110_RS19415	COG3119	arylsulfatase activity
Pan110_RS19440	COG0530	calcium, potassium:sodium antiporter activity
Pan110_RS19455	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Pan110_RS19475	COG1067	ATP-dependent peptidase activity
Pan110_RS19500	COG2308	Evidence 4 Homologs of previously reported genes of
Pan110_RS19515	COG2308	Evidence 4 Homologs of previously reported genes of
Pan110_RS19515	COG2307	Protein conserved in bacteria
Pan110_RS19595	COG3152	Membrane
Pan110_RS19640	COG0515	serine threonine protein kinase
Pan110_RS19640	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Pan110_RS19690	COG0653	protein targeting
Pan110_RS19715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Pan110_RS19725	COG3541	Predicted nucleotidyltransferase
Pan110_RS19745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Pan110_RS19750	COG0798	PFAM Bile acid sodium symporter
Pan110_RS19765	COG0640	Transcriptional regulator
Pan110_RS19770	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Pan110_RS19775	COG4294	response to UV
Pan110_RS19795	COG3588	fructose-bisphosphate aldolase
Pan110_RS19835	COG0431	NADPH-dependent FMN reductase
Pan110_RS19845	COG1741	Belongs to the pirin family
Pan110_RS19850	COG1846	Transcriptional regulator
Pan110_RS19865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Pan110_RS19880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Pan110_RS19885	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Pan110_RS19890	COG3663	DNA glycosylase
Pan110_RS19910	COG1215	transferase activity, transferring glycosyl groups
Pan110_RS19915	COG0579	oxidoreductase
Pan110_RS19920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Pan110_RS19930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Pan110_RS19940	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Pan110_RS19945	COG0328	RNA-DNA hybrid ribonuclease activity
Pan110_RS19950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Pan110_RS19965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS19975	COG0321	lipoyl(octanoyl) transferase activity
Pan110_RS19980	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Pan110_RS19995	COG1774	PSP1 C-terminal conserved region
Pan110_RS20005	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Pan110_RS20010	COG0799	negative regulation of ribosome biogenesis
Pan110_RS20015	COG0018	arginyl-trna synthetase
Pan110_RS20025	COG0202	RNA polymerase activity
Pan110_RS20035	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Pan110_RS20040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Pan110_RS20050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Pan110_RS20055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Pan110_RS20070	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Pan110_RS20075	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Pan110_RS20125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Pan110_RS20155	COG4589	Belongs to the CDS family
Pan110_RS20180	COG2610	gluconate transmembrane transporter activity
Pan110_RS20195	COG1449	Belongs to the glycosyl hydrolase 57 family
Pan110_RS20205	COG0297	glycogen (starch) synthase activity
Pan110_RS20210	COG3852	Histidine kinase
Pan110_RS20215	COG2204	response regulator
Pan110_RS20235	COG2205	protein histidine kinase activity
Pan110_RS20235	COG0784	Response regulator, receiver
Pan110_RS20240	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Pan110_RS20250	COG3119	arylsulfatase activity
Pan110_RS20255	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Pan110_RS20260	COG2226	methyltransferase
Pan110_RS20275	COG1215	transferase activity, transferring glycosyl groups
Pan110_RS20335	COG1682	transport, permease protein
Pan110_RS20375	COG0653	protein targeting
Pan110_RS20380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Pan110_RS20395	COG0424	maF-like protein
Pan110_RS20445	COG2719	SpoVR family
Pan110_RS20450	COG2718	Belongs to the UPF0229 family
Pan110_RS20455	COG2766	serine protein kinase
Pan110_RS20465	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Pan110_RS20495	COG1368	sulfuric ester hydrolase activity
Pan110_RS20545	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Pan110_RS20570	COG4232	protein-disulfide reductase activity
Pan110_RS20575	COG2855	membrane
Pan110_RS20580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Pan110_RS20585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Pan110_RS20590	COG0113	porphobilinogen synthase activity
Pan110_RS20595	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Pan110_RS20620	COG0714	Associated with various cellular activities
Pan110_RS20630	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Pan110_RS20640	COG0515	serine threonine protein kinase
Pan110_RS20640	COG2815	serine threonine protein kinase
Pan110_RS20645	COG2115	Belongs to the xylose isomerase family
Pan110_RS20665	COG0728	peptidoglycan biosynthetic process
Pan110_RS20685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Pan110_RS20700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Pan110_RS20705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Pan110_RS20710	COG1454	alcohol dehydrogenase
Pan110_RS20720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Pan110_RS20740	COG1469	GTP cyclohydrolase I activity
Pan110_RS20755	COG1796	DNA polymerase
Pan110_RS20755	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Pan110_RS20760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Pan110_RS20795	COG1695	Transcriptional regulator
Pan110_RS20805	COG3386	PFAM SMP-30 Gluconolaconase
Pan110_RS20810	COG0508	dehydrogenase complex catalyzes the overall conversion of
Pan110_RS20815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Pan110_RS20820	COG0095	Lipoate-protein ligase
Pan110_RS20825	COG0534	Mate efflux family protein
Pan110_RS20830	COG1132	(ABC) transporter
Pan110_RS20850	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Pan110_RS20860	COG3119	arylsulfatase activity
Pan110_RS20895	COG0519	Catalyzes the synthesis of GMP from XMP
Pan110_RS20895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Pan110_RS20930	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Pan110_RS20935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Pan110_RS20980	COG2186	Transcriptional regulator
Pan110_RS21030	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Pan110_RS21035	COG1082	Xylose isomerase domain protein TIM barrel
Pan110_RS21075	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Pan110_RS21080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Pan110_RS21105	COG0673	inositol 2-dehydrogenase activity
Pan110_RS21120	COG1082	Xylose isomerase domain protein TIM barrel
Pan110_RS21130	COG2610	gluconate transmembrane transporter activity
Pan110_RS21160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Pan110_RS21165	COG0358	DNA primase activity
Pan110_RS21180	COG1131	(ABC) transporter
Pan110_RS21240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Pan110_RS21265	COG0659	secondary active sulfate transmembrane transporter activity
Pan110_RS21280	COG2226	methyltransferase
Pan110_RS21285	COG0346	lactoylglutathione lyase activity
Pan110_RS21300	COG3119	arylsulfatase activity
Pan110_RS21350	COG3022	response to hydroperoxide
Pan110_RS21370	COG3781	membrane
Pan110_RS21375	COG0584	glycerophosphoryl diester phosphodiesterase
Pan110_RS21385	COG1846	Transcriptional regulator
Pan110_RS21400	COG1917	Cupin 2, conserved barrel domain protein
Pan110_RS21405	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Pan110_RS21410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Pan110_RS21415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Pan110_RS21440	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
Pan110_RS21445	COG1335	isochorismatase
Pan110_RS21450	COG1051	belongs to the nudix hydrolase family
Pan110_RS21450	COG1056	cytidyltransferase-related domain
Pan110_RS21455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Pan110_RS21455	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Pan110_RS21460	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Pan110_RS21480	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Pan110_RS21485	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Pan110_RS21490	COG0438	transferase activity, transferring glycosyl groups
Pan110_RS21490	COG1216	Glycosyl transferase, family 2
Pan110_RS21495	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Pan110_RS21510	COG3119	arylsulfatase activity
Pan110_RS21515	COG2815	serine threonine protein kinase
Pan110_RS21515	COG0515	serine threonine protein kinase
Pan110_RS21550	COG2172	sigma factor antagonist activity
Pan110_RS21565	COG1834	amidinotransferase
Pan110_RS21570	COG1164	Oligoendopeptidase f
Pan110_RS21575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Pan110_RS21580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Pan110_RS21580	COG2813	Specifically methylates the guanine in position
Pan110_RS21585	COG1192	Involved in chromosome partitioning
Pan110_RS21590	COG1902	pentaerythritol trinitrate reductase activity
Pan110_RS21595	COG4221	oxidoreductase activity
Pan110_RS21615	COG2088	sporulation resulting in formation of a cellular spore
Pan110_RS21620	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Pan110_RS21645	COG0616	signal peptide processing
Pan110_RS21680	COG4974	Belongs to the 'phage' integrase family
Pan110_RS21760	COG3328	transposase activity
Pan110_RS21775	COG2433	Pfam Transposase IS66
Pan110_RS21880	COG3328	transposase activity
Pan110_RS21890	COG2204	response regulator
Pan110_RS21895	COG3328	transposase activity
Pan110_RS21920	COG2433	Pfam Transposase IS66
Pan110_RS21945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Pan110_RS21970	COG3119	arylsulfatase activity
Pan110_RS21975	COG0529	Catalyzes the synthesis of activated sulfate
Pan110_RS21980	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Pan110_RS21990	COG0575	Belongs to the CDS family
Pan110_RS22000	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Pan110_RS22015	COG0673	inositol 2-dehydrogenase activity
Pan110_RS22040	COG0142	geranyltranstransferase activity
Pan110_RS22055	COG0509	glycine decarboxylation via glycine cleavage system
Pan110_RS22085	COG3739	integral membrane protein
Pan110_RS22095	COG3119	arylsulfatase activity
Pan110_RS22095	COG3408	Glycogen debranching enzyme
Pan110_RS22110	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Pan110_RS22125	COG0537	adenosine 5'-monophosphoramidase activity
Pan110_RS22140	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Pan110_RS22160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Pan110_RS22180	COG3119	arylsulfatase activity
Pan110_RS22240	COG1468	defense response to virus
Pan110_RS22240	COG1518	maintenance of DNA repeat elements
Pan110_RS22245	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Pan110_RS22300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Pan110_RS22350	COG3328	transposase activity
Pan110_RS22360	COG0659	secondary active sulfate transmembrane transporter activity
Pan110_RS22405	COG1131	(ABC) transporter
Pan110_RS22410	COG0842	Transport permease protein
Pan110_RS22415	COG0842	Transport permease protein
Pan110_RS22500	COG2226	methyltransferase
Pan110_RS22545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Pan110_RS22555	COG0798	PFAM Bile acid sodium symporter
Pan110_RS22575	COG0640	Transcriptional regulator
Pan110_RS22585	COG0789	Transcriptional regulator
Pan110_RS22600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Pan110_RS22610	COG2801	Transposase and inactivated derivatives
Pan110_RS22635	COG0463	Glycosyl transferase, family 2
Pan110_RS22640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Pan110_RS22660	COG0463	Glycosyl transferase, family 2
Pan110_RS22665	COG1595	DNA-templated transcription, initiation
Pan110_RS22700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Pan110_RS22710	COG3415	Transposase
Pan110_RS22735	COG0316	Belongs to the HesB IscA family
Pan110_RS22740	COG0719	Fe-S assembly protein
Pan110_RS22745	COG0396	ATPase activity
Pan110_RS22750	COG0719	Fe-S assembly protein
Pan110_RS22755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Pan110_RS22775	COG0354	folic acid binding
Pan110_RS22785	COG0351	phosphomethylpyrimidine kinase
Pan110_RS22810	COG2801	Transposase and inactivated derivatives
Pan110_RS22835	COG3119	arylsulfatase activity
Pan110_RS22840	COG1914	H( )-stimulated, divalent metal cation uptake system
Pan110_RS22845	COG3119	arylsulfatase activity
Pan110_RS22850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Pan110_RS22855	COG2706	6-phosphogluconolactonase activity
Pan110_RS22870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Pan110_RS22900	COG3328	transposase activity
Pan110_RS22915	COG2433	Pfam Transposase IS66
Pan110_RS22945	COG3328	transposase activity
Pan110_RS22995	COG2255	four-way junction helicase activity
Pan110_RS23015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Pan110_RS23020	COG0372	Belongs to the citrate synthase family
Pan110_RS23045	COG0367	asparagine synthase
Pan110_RS23055	COG0318	PFAM AMP-dependent synthetase and ligase
Pan110_RS23060	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Pan110_RS23065	COG0726	polysaccharide deacetylase
Pan110_RS23070	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Pan110_RS23075	COG0563	adenylate kinase activity
Pan110_RS23080	COG3119	arylsulfatase activity
Pan110_RS23130	COG4285	Biotin-protein ligase, N terminal
Pan110_RS23140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS23150	COG0456	acetyltransferase
Pan110_RS23175	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Pan110_RS23200	COG0659	secondary active sulfate transmembrane transporter activity
Pan110_RS23220	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Pan110_RS23230	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Pan110_RS23245	COG1088	dTDP-glucose 4,6-dehydratase activity
Pan110_RS23305	COG0673	inositol 2-dehydrogenase activity
Pan110_RS23320	COG3328	transposase activity
Pan110_RS23330	COG3328	transposase activity
Pan110_RS23350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Pan110_RS23365	COG2239	Acts as a magnesium transporter
Pan110_RS23425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS23430	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Pan110_RS23435	COG0545	Peptidyl-prolyl cis-trans isomerase
Pan110_RS23455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Pan110_RS23460	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Pan110_RS23465	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Pan110_RS23475	COG2204	response regulator
Pan110_RS23485	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Pan110_RS23490	COG1872	DUF167
Pan110_RS23510	COG1940	carbohydrate kinase activity
Pan110_RS23515	COG0248	Ppx GppA phosphatase
Pan110_RS23520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Pan110_RS23525	COG0673	inositol 2-dehydrogenase activity
Pan110_RS23550	COG2346	COG2346, Truncated hemoglobins
Pan110_RS23575	COG0174	glutamine synthetase
Pan110_RS23580	COG2186	Transcriptional regulator
Pan110_RS23595	COG0673	inositol 2-dehydrogenase activity
Pan110_RS23600	COG3119	arylsulfatase activity
Pan110_RS23605	COG3119	arylsulfatase activity
Pan110_RS23620	COG2192	nodulation
Pan110_RS23645	COG1136	(ABC) transporter
Pan110_RS23645	COG0577	efflux transmembrane transporter activity
Pan110_RS23650	COG1136	(ABC) transporter
Pan110_RS23655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Pan110_RS23670	COG3119	arylsulfatase activity
Pan110_RS23690	COG0539	negative regulation of cytoplasmic translation
Pan110_RS23695	COG0515	serine threonine protein kinase
Pan110_RS23695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Pan110_RS23705	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Pan110_RS23745	COG0300	oxidoreductase activity
Pan110_RS23780	COG0446	pyridine nucleotide-disulphide oxidoreductase
Pan110_RS23795	COG0473	3-isopropylmalate dehydrogenase activity
Pan110_RS23795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Pan110_RS23810	COG4948	Mandelate Racemase Muconate Lactonizing
Pan110_RS23815	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Pan110_RS23820	COG1312	Catalyzes the dehydration of D-mannonate
Pan110_RS23830	COG0673	inositol 2-dehydrogenase activity
Pan110_RS23835	COG2204	response regulator
Pan110_RS23840	COG1597	lipid kinase activity
Pan110_RS23845	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Pan110_RS23870	COG1063	alcohol dehydrogenase
Pan110_RS23875	COG0156	8-amino-7-oxononanoate synthase activity
Pan110_RS23890	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Pan110_RS23900	COG0519	Catalyzes the synthesis of GMP from XMP
Pan110_RS23900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Pan110_RS23950	COG2226	methyltransferase
Pan110_RS23955	COG0464	growth
Pan110_RS23975	COG0673	inositol 2-dehydrogenase activity
Pan110_RS24010	COG3458	cephalosporin-C deacetylase activity
Pan110_RS24015	COG5285	phytanoyl-CoA dioxygenase
Pan110_RS24100	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Pan110_RS24100	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Pan110_RS24110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Pan110_RS24125	COG1078	dGTPase activity
Pan110_RS24130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Pan110_RS24135	COG0569	domain protein
Pan110_RS24145	COG0004	ammonium transporteR
Pan110_RS24150	COG0459	protein refolding
Pan110_RS24155	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Pan110_RS24160	COG0459	protein refolding
Pan110_RS24165	COG0484	heat shock protein binding
Pan110_RS24170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Pan110_RS24195	COG0673	inositol 2-dehydrogenase activity
Pan110_RS24210	COG0432	Pfam Uncharacterised protein family UPF0047
Pan110_RS24215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Pan110_RS24240	COG1271	oxidase subunit
Pan110_RS24245	COG1294	oxidase, subunit
Pan110_RS24260	COG1070	Carbohydrate kinase
Pan110_RS24270	COG1028	Short-chain dehydrogenase reductase Sdr
Pan110_RS24290	COG0165	Argininosuccinate lyase
Pan110_RS24320	COG2166	iron-sulfur cluster assembly
Pan110_RS24325	COG0489	protein tyrosine kinase activity
Pan110_RS24360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Pan110_RS24365	COG1278	Cold shock
Pan110_RS24390	COG1321	iron dependent repressor
Pan110_RS24400	COG3119	arylsulfatase activity
Pan110_RS24415	COG3119	arylsulfatase activity
Pan110_RS24440	COG0584	glycerophosphoryl diester phosphodiesterase
Pan110_RS24465	COG1061	Type III restriction enzyme res subunit
Pan110_RS24470	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Pan110_RS24480	COG0069	glutamate synthase activity
Pan110_RS24485	COG0174	glutamine synthetase
Pan110_RS24500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Pan110_RS24500	COG0446	pyridine nucleotide-disulphide oxidoreductase
Pan110_RS24520	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Pan110_RS24530	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Pan110_RS24535	COG1640	4-alpha-glucanotransferase
Pan110_RS24545	COG2226	methyltransferase
Pan110_RS24550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Pan110_RS24565	COG0673	inositol 2-dehydrogenase activity
Pan110_RS24575	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Pan110_RS24590	COG1136	(ABC) transporter
Pan110_RS24590	COG0577	efflux transmembrane transporter activity
Pan110_RS24595	COG1136	(ABC) transporter
Pan110_RS24610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS24635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Pan110_RS24660	COG3119	arylsulfatase activity
Pan110_RS24710	COG2207	Transcriptional regulator
Pan110_RS24745	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Pan110_RS24745	COG0517	IMP dehydrogenase activity
Pan110_RS24745	COG0617	tRNA 3'-terminal CCA addition
Pan110_RS24755	COG4864	UPF0365 protein
Pan110_RS24760	COG3781	membrane
Pan110_RS24775	COG3459	Glycosyltransferase 36 associated
Pan110_RS24785	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Pan110_RS24795	COG3415	Transposase
Pan110_RS24835	COG0811	peptide transport
Pan110_RS24855	COG4956	integral membrane protein (PIN domain superfamily)
Pan110_RS24880	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Pan110_RS24885	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Pan110_RS24895	COG0436	Aminotransferase
Pan110_RS24905	COG3695	enzyme binding
Pan110_RS24955	COG1381	Involved in DNA repair and RecF pathway recombination
Pan110_RS24975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Pan110_RS25000	COG0826	peptidase U32
Pan110_RS25060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Pan110_RS25085	COG4935	Belongs to the peptidase S8 family
Pan110_RS25085	COG2234	aminopeptidase activity
Pan110_RS25125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Pan110_RS25130	COG0318	PFAM AMP-dependent synthetase and ligase
Pan110_RS25155	COG3961	Belongs to the TPP enzyme family
Pan110_RS25160	COG0281	malic enzyme
Pan110_RS25240	COG2755	lipolytic protein G-D-S-L family
Pan110_RS25240	COG0657	acetylesterase activity
Pan110_RS25250	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Pan110_RS25270	COG3540	Alkaline phosphatase
Pan110_RS25275	COG5002	protein histidine kinase activity
Pan110_RS25275	COG2205	protein histidine kinase activity
Pan110_RS25275	COG0784	Response regulator, receiver
Pan110_RS25305	COG3119	arylsulfatase activity
Pan110_RS25315	COG0736	holo-[acyl-carrier-protein] synthase activity
Pan110_RS25325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Pan110_RS25330	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Pan110_RS25335	COG0750	zinc metalloprotease
Pan110_RS25350	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Pan110_RS25375	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Pan110_RS25380	COG1419	protein localization to endoplasmic reticulum
Pan110_RS25385	COG0455	bacterial-type flagellum organization
Pan110_RS25395	COG1191	sigma factor activity
Pan110_RS25400	COG0714	Associated with various cellular activities
Pan110_RS25430	COG0039	L-malate dehydrogenase activity
Pan110_RS25435	COG0235	Class ii aldolase
Pan110_RS25470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Pan110_RS25475	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Pan110_RS25485	COG4869	propanediol catabolic process
Pan110_RS25490	COG1349	DNA-binding transcription factor activity
Pan110_RS25500	COG2132	Multicopper oxidase
Pan110_RS25515	COG3118	belongs to the thioredoxin family
Pan110_RS25535	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Pan110_RS25540	COG0109	protoheme IX farnesyltransferase activity
Pan110_RS25555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Pan110_RS25560	COG0242	peptide deformylase activity
Pan110_RS25615	COG0477	Major facilitator Superfamily
Pan110_RS25660	COG0659	secondary active sulfate transmembrane transporter activity
Pan110_RS25665	COG1671	Belongs to the UPF0178 family
Pan110_RS25750	COG2433	Pfam Transposase IS66
Pan110_RS25765	COG2433	Pfam Transposase IS66
Pan110_RS25785	COG3328	transposase activity
Pan110_RS25820	COG0527	aspartate kinase activity
Pan110_RS25820	COG0460	homoserine dehydrogenase
Pan110_RS25825	COG3328	transposase activity
Pan110_RS25830	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Pan110_RS25835	COG1982	Orn Lys Arg decarboxylase major
Pan110_RS25850	COG1192	Involved in chromosome partitioning
Pan110_RS25855	COG1475	DNA binding
Pan110_RS25870	COG2337	Toxic component of a toxin-antitoxin (TA) module
Pan110_RS25930	COG2433	Pfam Transposase IS66
Pan110_RS25950	COG1674	ftsk spoiiie
Pan110_RS25960	COG3328	transposase activity
Pan110_RS26020	COG2433	Pfam Transposase IS66
Pan110_RS26070	COG0179	Fumarylacetoacetate (FAA) hydrolase
Pan110_RS26075	COG0842	Transport permease protein
Pan110_RS26075	COG1129	ABC transporter
Pan110_RS26100	COG2095	MarC family integral membrane protein
Pan110_RS26105	COG3119	arylsulfatase activity
Pan110_RS26110	COG0673	inositol 2-dehydrogenase activity
Pan110_RS26140	COG2226	methyltransferase
Pan110_RS26150	COG1082	Xylose isomerase domain protein TIM barrel
Pan110_RS26165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Pan110_RS26175	COG1475	DNA binding
Pan110_RS26195	COG0740	serine-type endopeptidase activity
Pan110_RS26200	COG0740	serine-type endopeptidase activity
Pan110_RS26250	COG1459	type II secretion system
Pan110_RS26255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Pan110_RS26265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Pan110_RS26270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Pan110_RS26275	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Pan110_RS26280	COG0314	molybdopterin synthase activity
Pan110_RS26285	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Pan110_RS26290	COG0277	FAD linked oxidase domain protein
Pan110_RS26305	COG3956	TIGRFAM MazG family protein
Pan110_RS26310	COG2423	ornithine cyclodeaminase activity
Pan110_RS26320	COG3958	Transketolase
Pan110_RS26325	COG3959	Transketolase, thiamine diphosphate binding domain
Pan110_RS26335	COG3119	arylsulfatase activity
Pan110_RS26345	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Pan110_RS26355	COG1013	pyruvate-flavodoxin oxidoreductase activity
Pan110_RS26360	COG0674	pyruvate-flavodoxin oxidoreductase activity
Pan110_RS26360	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Pan110_RS26375	COG3119	arylsulfatase activity
Pan110_RS26420	COG3119	arylsulfatase activity
Pan110_RS26450	COG0657	acetylesterase activity
Pan110_RS26450	COG2755	lipolytic protein G-D-S-L family
Pan110_RS26515	COG0328	RNA-DNA hybrid ribonuclease activity
Pan110_RS26515	COG3341	Caulimovirus viroplasmin
Pan110_RS26540	COG0484	heat shock protein binding
Pan110_RS26580	COG0202	RNA polymerase activity
Pan110_RS26605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Pan110_RS26685	COG5002	protein histidine kinase activity
Pan110_RS26740	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Pan110_RS26745	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Pan110_RS26840	COG0657	acetylesterase activity
Pan110_RS26860	COG1643	Atp-dependent helicase
Pan110_RS26865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Pan110_RS26870	COG0493	'glutamate synthase
Pan110_RS26870	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Pan110_RS26875	COG1040	competence protein
Pan110_RS26885	COG0181	hydroxymethylbilane synthase activity
Pan110_RS26890	COG0372	Belongs to the citrate synthase family
Pan110_RS26905	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Pan110_RS26915	COG4946	Tricorn protease homolog
Pan110_RS26915	COG1506	peptidase
Pan110_RS26915	COG0823	Involved in the tonB-independent uptake of proteins
Pan110_RS26920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Pan110_RS26930	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Pan110_RS26935	COG3119	arylsulfatase activity
Pan110_RS26950	COG3119	arylsulfatase activity
Pan110_RS26965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Pan110_RS26970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Pan110_RS26980	COG2234	aminopeptidase activity
Pan110_RS26985	COG3132	Protein of unknown function, DUF480
Pan110_RS26990	COG3119	arylsulfatase activity
Pan110_RS27010	COG1402	creatininase
Pan110_RS27100	COG0569	domain protein
Pan110_RS27110	COG1028	Short-chain dehydrogenase reductase Sdr
Pan110_RS27135	COG1028	Short-chain dehydrogenase reductase Sdr
Pan110_RS27145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Pan110_RS27150	COG1028	Short-chain dehydrogenase reductase Sdr
Pan110_RS27155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Pan110_RS27160	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Pan110_RS27165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Pan110_RS27180	COG0420	3'-5' exonuclease activity
Pan110_RS27185	COG4717	serine-type aminopeptidase activity
Pan110_RS27190	COG1058	Belongs to the CinA family
Pan110_RS27190	COG1546	Belongs to the CinA family
Pan110_RS27205	COG4864	UPF0365 protein
Pan110_RS27225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Pan110_RS27235	COG1136	(ABC) transporter
Pan110_RS27265	COG0129	dihydroxy-acid dehydratase activity
Pan110_RS27290	COG3385	transposase activity
Pan110_RS27295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Pan110_RS27315	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Pan110_RS27325	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Pan110_RS27330	COG1028	Short-chain dehydrogenase reductase Sdr
Pan110_RS27335	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Pan110_RS27340	COG1028	Short-chain dehydrogenase reductase Sdr
Pan110_RS27350	COG2205	protein histidine kinase activity
Pan110_RS27350	COG0784	Response regulator, receiver
Pan110_RS27370	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Pan110_RS27375	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Pan110_RS27390	COG2204	response regulator
Pan110_RS27435	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Pan110_RS27440	COG1045	serine acetyltransferase
Pan110_RS27455	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Pan110_RS27465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS27470	COG0571	ribonuclease III activity
Pan110_RS27515	COG0203	ribosomal protein L17
Pan110_RS27520	COG0202	RNA polymerase activity
Pan110_RS27525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Pan110_RS27530	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Pan110_RS27535	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Pan110_RS27540	COG0201	protein transport
Pan110_RS27545	COG0200	Binds to the 23S rRNA
Pan110_RS27550	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Pan110_RS27555	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Pan110_RS27560	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Pan110_RS27565	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Pan110_RS27570	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Pan110_RS27575	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Pan110_RS27580	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Pan110_RS27585	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Pan110_RS27590	COG0255	Belongs to the universal ribosomal protein uL29 family
Pan110_RS27595	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Pan110_RS27600	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Pan110_RS27605	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Pan110_RS27610	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Pan110_RS27615	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Pan110_RS27620	COG0089	rRNA binding
Pan110_RS27625	COG0088	Forms part of the polypeptide exit tunnel
Pan110_RS27630	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Pan110_RS27635	COG0051	transcription antitermination factor activity, RNA binding
Pan110_RS27640	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Pan110_RS27645	COG0049	tRNA binding
Pan110_RS27650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Pan110_RS27655	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Pan110_RS27660	COG0085	RNA polymerase activity
Pan110_RS27665	COG0222	ribosome binding
Pan110_RS27670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Pan110_RS27675	COG0081	regulation of translation
Pan110_RS27680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Pan110_RS27685	COG0250	Participates in transcription elongation, termination and antitermination
Pan110_RS27705	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Pan110_RS27730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Pan110_RS27760	COG1136	(ABC) transporter
Pan110_RS27760	COG0577	efflux transmembrane transporter activity
Pan110_RS27775	COG0071	Belongs to the small heat shock protein (HSP20) family
Pan110_RS27785	COG1477	protein flavinylation
Pan110_RS27795	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Pan110_RS27800	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Pan110_RS27810	COG1805	sodium ion transport
Pan110_RS27815	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Pan110_RS27825	COG3119	arylsulfatase activity
Pan110_RS27830	COG1940	carbohydrate kinase activity
Pan110_RS27835	COG0481	GTPase activity
Pan110_RS27865	COG3481	metal-dependent phosphohydrolase, HD sub domain
Pan110_RS27870	COG0316	Belongs to the HesB IscA family
Pan110_RS27875	COG1028	Short-chain dehydrogenase reductase Sdr
Pan110_RS27895	COG1137	ATPase activity
Pan110_RS27900	COG0681	Belongs to the peptidase S26 family
Pan110_RS27920	COG1845	cytochrome c oxidase, subunit III
Pan110_RS27930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Pan110_RS27935	COG2010	Cytochrome c
Pan110_RS27935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Pan110_RS27965	COG0437	4 iron, 4 sulfur cluster binding
Pan110_RS27980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Pan110_RS28025	COG3119	arylsulfatase activity
Pan110_RS28040	COG3119	arylsulfatase activity
Pan110_RS28065	COG0861	Integral membrane protein TerC family
Pan110_RS28075	COG1028	Short-chain dehydrogenase reductase Sdr
Pan110_RS28100	COG1858	cytochrome C peroxidase
Pan110_RS28140	COG1131	(ABC) transporter
Pan110_RS28145	COG1725	Transcriptional regulator
Pan110_RS28150	COG3119	arylsulfatase activity
Pan110_RS28175	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Pan110_RS28175	COG3064	Membrane
Pan110_RS28175	COG1073	alpha beta
Pan110_RS28200	COG0076	glutamate decarboxylase activity
Pan110_RS28245	COG2226	methyltransferase
Pan110_RS28260	COG0134	indole-3-glycerol-phosphate synthase activity
Pan110_RS28265	COG4112	unkown
Pan110_RS28280	COG1007	ATP synthesis coupled electron transport
Pan110_RS28290	COG2204	response regulator
Pan110_RS28300	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Pan110_RS28310	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Pan110_RS28315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Pan110_RS28320	COG0405	Gamma-glutamyltransferase
Pan110_RS28335	COG1063	alcohol dehydrogenase
Pan110_RS28340	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Pan110_RS28355	COG0006	proline dipeptidase activity
Pan110_RS28360	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Pan110_RS28370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Pan110_RS28370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Pan110_RS28375	COG0653	protein targeting
Pan110_RS28380	COG0626	cystathionine gamma-synthase activity
Pan110_RS28385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Pan110_RS28415	COG2204	response regulator
Pan110_RS28470	COG0363	glucosamine-6-phosphate deaminase activity
Pan110_RS28475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Pan110_RS28480	COG3119	arylsulfatase activity
Pan110_RS28530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Pan110_RS28535	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Pan110_RS28545	COG0848	biopolymer transport protein
Pan110_RS28570	COG0793	Belongs to the peptidase S41A family
Pan110_RS28575	COG0009	L-threonylcarbamoyladenylate synthase
Pan110_RS28580	COG2205	protein histidine kinase activity
Pan110_RS28580	COG0784	Response regulator, receiver
Pan110_RS28585	COG2201	protein-glutamate methylesterase activity
Pan110_RS28590	COG0657	acetylesterase activity
Pan110_RS28645	COG0017	Asparaginyl-tRNA synthetase
Pan110_RS28665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Pan110_RS28670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Pan110_RS28805	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Pan110_RS28815	COG3119	arylsulfatase activity
Pan110_RS28830	COG0500	methyltransferase
Pan110_RS28835	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Pan110_RS28835	COG0758	DNA mediated transformation
Pan110_RS28840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Pan110_RS28840	COG0730	response to heat
Pan110_RS28845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Pan110_RS28850	COG2363	Small membrane protein
Pan110_RS28895	COG0004	ammonium transporteR
Pan110_RS28900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Pan110_RS28905	COG0352	thiamine-phosphate diphosphorylase activity
Pan110_RS28910	COG0542	response to heat
Pan110_RS28915	COG2226	methyltransferase
Pan110_RS28920	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Pan110_RS28925	COG1966	Carbon starvation protein
Pan110_RS28975	COG1162	GTPase activity
Pan110_RS28995	COG1404	Belongs to the peptidase S8 family
Pan110_RS29010	COG3119	arylsulfatase activity
Pan110_RS29025	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Pan110_RS29025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Pan110_RS29045	COG0438	transferase activity, transferring glycosyl groups
Pan110_RS29060	COG0516	GMP reductase activity
Pan110_RS29060	COG0517	IMP dehydrogenase activity
Pan110_RS29065	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Pan110_RS29080	COG0688	phosphatidylethanolamine metabolic process
Pan110_RS29085	COG0148	phosphopyruvate hydratase activity
Pan110_RS29105	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Pan110_RS29145	COG1129	ABC transporter
Pan110_RS29150	COG1172	Belongs to the binding-protein-dependent transport system permease family
Pan110_RS29160	COG0653	protein targeting
Pan110_RS29175	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Pan110_RS29185	COG0469	pyruvate kinase activity
Pan110_RS29190	COG1331	Highly conserved protein containing a thioredoxin domain
Pan110_RS29195	COG0714	Associated with various cellular activities
Pan110_RS29205	COG0714	Associated with various cellular activities
Pan110_RS29230	COG0004	ammonium transporteR
Pan110_RS29235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Pan110_RS29265	COG3119	arylsulfatase activity
Pan110_RS29275	COG0116	Belongs to the methyltransferase superfamily
Pan110_RS29280	COG0210	DNA helicase
Pan110_RS29290	COG0673	inositol 2-dehydrogenase activity
Pan110_RS29335	COG0515	serine threonine protein kinase
Pan110_RS29335	COG2815	serine threonine protein kinase
Pan110_RS29350	COG2226	methyltransferase
Pan110_RS29355	COG4191	Histidine kinase
Pan110_RS29360	COG0038	chloride channel
Pan110_RS29405	COG1397	ADP-ribosylglycohydrolase
Pan110_RS29455	COG1914	H( )-stimulated, divalent metal cation uptake system
Pan110_RS29460	COG0778	Nitroreductase
Pan110_RS29485	COG1073	alpha beta
Pan110_RS29580	COG3608	succinylglutamate desuccinylase aspartoacylase
Pan110_RS29580	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Pan110_RS29595	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Pan110_RS29665	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Pan110_RS29700	COG3119	arylsulfatase activity
Pan110_RS29720	COG2824	Alkylphosphonate utilization operon protein PhnA
Pan110_RS29770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Pan110_RS29805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Pan110_RS29820	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Pan110_RS29825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Pan110_RS29830	COG4221	oxidoreductase activity
Pan110_RS29835	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Pan110_RS29840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Pan110_RS29850	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Pan110_RS29900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Pan110_RS29905	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Pan110_RS29910	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Pan110_RS29925	COG3119	arylsulfatase activity
Pan110_RS29940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Pan110_RS29955	COG0436	Aminotransferase
Pan110_RS30020	COG1450	Type ii and iii secretion system protein
Pan110_RS30030	COG5002	protein histidine kinase activity
Pan110_RS30035	COG0745	RESPONSE REGULATOR receiver
Pan110_RS30040	COG3706	GGDEF domain
Pan110_RS30050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Pan110_RS30060	COG1459	type II secretion system
Pan110_RS30065	COG0628	permease