locus-tag	class	description
BBI15_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BBI15_RS00010	COG0592	DNA-directed DNA polymerase activity
BBI15_RS00015	COG2501	S4 domain
BBI15_RS00030	COG0187	DNA topoisomerase II activity
BBI15_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBI15_RS00055	COG0517	IMP dehydrogenase activity
BBI15_RS00055	COG0516	GMP reductase activity
BBI15_RS00065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBI15_RS00075	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BBI15_RS00085	COG0596	Alpha beta hydrolase
BBI15_RS00090	COG0590	tRNA wobble adenosine to inosine editing
BBI15_RS00095	COG1428	Deoxynucleoside kinase
BBI15_RS00100	COG1428	Deoxynucleoside kinase
BBI15_RS00115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBI15_RS00120	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BBI15_RS00125	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BBI15_RS00145	COG1982	Orn Lys Arg decarboxylase major
BBI15_RS00155	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BBI15_RS00160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BBI15_RS00165	COG3870	Protein conserved in bacteria
BBI15_RS00170	COG0470	DNA polymerase III
BBI15_RS00175	COG1774	PSP1 C-terminal conserved region
BBI15_RS00180	COG4467	Involved in initiation control of chromosome replication
BBI15_RS00185	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BBI15_RS00195	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BBI15_RS00200	COG2002	toxin-antitoxin pair type II binding
BBI15_RS00210	COG0084	hydrolase, TatD family'
BBI15_RS00215	COG3584	3D domain protein
BBI15_RS00215	COG3583	domain protein
BBI15_RS00230	COG4466	Protein conserved in bacteria
BBI15_RS00235	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BBI15_RS00240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBI15_RS00245	COG0251	oxidation-reduction process
BBI15_RS00255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BBI15_RS00270	COG0193	aminoacyl-tRNA hydrolase activity
BBI15_RS00275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BBI15_RS00280	COG2244	polysaccharide biosynthetic process
BBI15_RS00285	COG3956	TIGRFAM MazG family protein
BBI15_RS00290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BBI15_RS00295	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BBI15_RS00300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BBI15_RS00305	COG0505	Belongs to the CarA family
BBI15_RS00310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BBI15_RS00315	COG1098	S1 RNA binding domain
BBI15_RS00335	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BBI15_RS00340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBI15_RS00345	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BBI15_RS00350	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BBI15_RS00355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBI15_RS00360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BBI15_RS00365	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BBI15_RS00370	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BBI15_RS00375	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BBI15_RS00380	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BBI15_RS00485	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BBI15_RS00490	COG0542	response to heat
BBI15_RS00495	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BBI15_RS00500	COG4956	integral membrane protein (PIN domain superfamily)
BBI15_RS00510	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BBI15_RS00520	COG1045	serine acetyltransferase
BBI15_RS00535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBI15_RS00540	COG3688	RNA-binding protein containing a PIN domain
BBI15_RS00550	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBI15_RS00575	COG0222	ribosome binding
BBI15_RS00580	COG2813	Specifically methylates the guanine in position
BBI15_RS00595	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BBI15_RS00600	COG0049	tRNA binding
BBI15_RS00620	COG0028	Belongs to the TPP enzyme family
BBI15_RS00625	COG0440	acetolactate synthase activity
BBI15_RS00650	COG0066	3-isopropylmalate dehydratase activity
BBI15_RS00655	COG2056	Na+-H+ antiporter family
BBI15_RS00680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BBI15_RS00705	COG0255	Belongs to the universal ribosomal protein uL29 family
BBI15_RS00710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BBI15_RS00715	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BBI15_RS00760	COG0201	protein transport
BBI15_RS00770	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BBI15_RS00785	COG0202	RNA polymerase activity
BBI15_RS00795	COG1122	ATPase activity
BBI15_RS00805	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBI15_RS00810	COG0101	tRNA pseudouridine synthase activity
BBI15_RS00815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BBI15_RS00830	COG0489	protein tyrosine kinase activity
BBI15_RS00835	COG2194	sulfuric ester hydrolase activity
BBI15_RS00890	COG0372	Belongs to the citrate synthase family
BBI15_RS00910	COG1595	DNA-templated transcription, initiation
BBI15_RS00915	COG5662	AntiSigma factor
BBI15_RS00920	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BBI15_RS00935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBI15_RS00940	COG3708	Transcriptional regulator
BBI15_RS00940	COG2207	Transcriptional regulator
BBI15_RS00945	COG0431	NADPH-dependent FMN reductase
BBI15_RS00950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBI15_RS00965	COG1695	Transcriptional regulator
BBI15_RS00975	COG1253	flavin adenine dinucleotide binding
BBI15_RS00980	COG1253	flavin adenine dinucleotide binding
BBI15_RS00985	COG1253	flavin adenine dinucleotide binding
BBI15_RS00990	COG0861	Integral membrane protein TerC family
BBI15_RS00995	COG0488	(ABC) transporter
BBI15_RS01000	COG1136	(ABC) transporter
BBI15_RS01005	COG0577	efflux transmembrane transporter activity
BBI15_RS01015	COG5002	protein histidine kinase activity
BBI15_RS01015	COG3850	Histidine kinase
BBI15_RS01030	COG2050	protein possibly involved in aromatic compounds catabolism
BBI15_RS01035	COG5646	InterPro IPR014922
BBI15_RS01040	COG5001	Diguanylate cyclase
BBI15_RS01040	COG3300	MHYT domain
BBI15_RS01050	COG1366	Belongs to the anti-sigma-factor antagonist family
BBI15_RS01055	COG3437	response regulator, receiver
BBI15_RS01070	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BBI15_RS01075	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BBI15_RS01080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBI15_RS01095	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BBI15_RS01105	COG1516	flagellar protein fliS
BBI15_RS01110	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BBI15_RS01115	COG1360	Flagellar Motor Protein
BBI15_RS01140	COG1256	bacterial-type flagellum assembly
BBI15_RS01140	COG4786	Flagellar basal body rod
BBI15_RS01145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBI15_RS01150	COG4786	Flagellar basal body rod
BBI15_RS01155	COG4786	Flagellar basal body rod
BBI15_RS01160	COG1815	bacterial-type flagellum-dependent cell motility
BBI15_RS01165	COG1558	bacterial-type flagellum-dependent cell motility
BBI15_RS01170	COG1677	Flagellar hook-basal body complex protein FliE
BBI15_RS01175	COG1766	The M ring may be actively involved in energy transduction
BBI15_RS01180	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBI15_RS01190	COG1157	protein secretion by the type III secretion system
BBI15_RS01195	COG2882	bacterial-type flagellum organization
BBI15_RS01205	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BBI15_RS01210	COG4786	Flagellar basal body rod
BBI15_RS01220	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBI15_RS01225	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBI15_RS01225	COG1776	CheC inhibitor of MCP methylation
BBI15_RS01230	COG3190	flagellar
BBI15_RS01235	COG1338	Plays a role in the flagellum-specific transport system
BBI15_RS01240	COG1987	bacterial-type flagellum assembly
BBI15_RS01245	COG1684	flagellar biosynthetic protein fliR
BBI15_RS01250	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBI15_RS01255	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBI15_RS01260	COG1419	protein localization to endoplasmic reticulum
BBI15_RS01265	COG0455	bacterial-type flagellum organization
BBI15_RS01270	COG1191	sigma factor activity
BBI15_RS01280	COG1728	Protein conserved in bacteria
BBI15_RS01290	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BBI15_RS01295	COG0235	Class ii aldolase
BBI15_RS01305	COG1850	ribulose-bisphosphate carboxylase activity
BBI15_RS01310	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BBI15_RS01315	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BBI15_RS01325	COG1129	ABC transporter
BBI15_RS01330	COG1172	Belongs to the binding-protein-dependent transport system permease family
BBI15_RS01345	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BBI15_RS01350	COG4336	lyase activity
BBI15_RS01355	COG1914	H( )-stimulated, divalent metal cation uptake system
BBI15_RS01360	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BBI15_RS01365	COG1984	allophanate hydrolase subunit 2
BBI15_RS01370	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BBI15_RS01375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBI15_RS01385	COG1131	(ABC) transporter
BBI15_RS01400	COG1346	cytolysis
BBI15_RS01405	COG1380	Effector of murein hydrolase LrgA
BBI15_RS01410	COG1114	Component of the transport system for branched-chain amino acids
BBI15_RS01415	COG1802	Transcriptional regulator
BBI15_RS01435	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BBI15_RS01440	COG2223	nitrite transmembrane transporter activity
BBI15_RS01445	COG1132	(ABC) transporter
BBI15_RS01450	COG0789	Transcriptional regulator
BBI15_RS01470	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BBI15_RS01480	COG2124	cytochrome p450
BBI15_RS01490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BBI15_RS01510	COG1366	Belongs to the anti-sigma-factor antagonist family
BBI15_RS01510	COG2202	Pas domain
BBI15_RS01525	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BBI15_RS01530	COG3409	Peptidoglycan-binding domain 1 protein
BBI15_RS01530	COG3773	Cell wall hydrolase
BBI15_RS01535	COG0395	ABC-type sugar transport system, permease component
BBI15_RS01540	COG1175	transmembrane transport
BBI15_RS01550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BBI15_RS01555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBI15_RS01555	COG0512	Glutamine amidotransferase of anthranilate synthase
BBI15_RS01560	COG1834	amidinotransferase
BBI15_RS01565	COG0322	excinuclease ABC activity
BBI15_RS01585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBI15_RS01590	COG0492	ferredoxin-NADP+ reductase activity
BBI15_RS01610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BBI15_RS01615	COG0390	transport system, permease component
BBI15_RS01625	COG1404	Belongs to the peptidase S8 family
BBI15_RS01635	COG5146	pantothenate kinase activity
BBI15_RS01640	COG0778	Nitroreductase
BBI15_RS01645	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BBI15_RS01650	COG1388	LysM domain
BBI15_RS01650	COG0791	NLP P60 protein
BBI15_RS01660	COG2050	protein possibly involved in aromatic compounds catabolism
BBI15_RS01665	COG1309	transcriptional regulator
BBI15_RS01675	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BBI15_RS01705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBI15_RS01710	COG2233	PERMEase
BBI15_RS01725	COG0346	lactoylglutathione lyase activity
BBI15_RS01730	COG0506	proline dehydrogenase activity
BBI15_RS01745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BBI15_RS01750	COG2706	6-phosphogluconolactonase activity
BBI15_RS01760	COG1999	signal sequence binding
BBI15_RS01770	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BBI15_RS01775	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BBI15_RS01785	COG0058	SHG alpha-glucan phosphorylase activity
BBI15_RS01790	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS01810	COG3949	Membrane
BBI15_RS01820	COG1234	tRNA 3'-trailer cleavage
BBI15_RS01825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBI15_RS01835	COG2233	PERMEase
BBI15_RS01840	COG1164	Oligoendopeptidase f
BBI15_RS01880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBI15_RS01885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BBI15_RS01900	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS01905	COG1960	acyl-CoA dehydrogenase activity
BBI15_RS01915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBI15_RS01920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BBI15_RS01925	COG1966	Carbon starvation protein
BBI15_RS01935	COG0003	Pfam Anion-transporting ATPase
BBI15_RS01940	COG0604	alcohol dehydrogenase
BBI15_RS01985	COG0427	acetyl-CoA hydrolase
BBI15_RS01995	COG1366	Belongs to the anti-sigma-factor antagonist family
BBI15_RS02010	COG1671	Belongs to the UPF0178 family
BBI15_RS02025	COG0628	permease
BBI15_RS02030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBI15_RS02035	COG0765	amino acid transport
BBI15_RS02040	COG1126	abc transporter atp-binding protein
BBI15_RS02050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BBI15_RS02055	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS02060	COG0492	ferredoxin-NADP+ reductase activity
BBI15_RS02070	COG3584	3D domain protein
BBI15_RS02070	COG1388	LysM domain
BBI15_RS02085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBI15_RS02090	COG0805	protein transport
BBI15_RS02100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BBI15_RS02100	COG0456	acetyltransferase
BBI15_RS02110	COG0598	Magnesium transport protein CorA
BBI15_RS02120	COG1733	regulation of RNA biosynthetic process
BBI15_RS02125	COG2514	catechol 2,3-dioxygenase activity
BBI15_RS02135	COG2070	2-Nitropropane dioxygenase
BBI15_RS02155	COG0628	permease
BBI15_RS02160	COG1846	Transcriptional regulator
BBI15_RS02165	COG2409	Drug exporters of the RND superfamily
BBI15_RS02165	COG1033	growth of symbiont in host cell
BBI15_RS02175	COG0456	acetyltransferase
BBI15_RS02185	COG1278	Cold shock
BBI15_RS02200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBI15_RS02225	COG0589	response to stress
BBI15_RS02240	COG0659	secondary active sulfate transmembrane transporter activity
BBI15_RS02250	COG4607	ABC-type enterochelin transport system periplasmic component
BBI15_RS02270	COG1846	Transcriptional regulator
BBI15_RS02275	COG0346	lactoylglutathione lyase activity
BBI15_RS02285	COG0307	riboflavin synthase, alpha
BBI15_RS02295	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BBI15_RS02310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBI15_RS02320	COG1876	peptidase activity
BBI15_RS02330	COG0702	epimerase
BBI15_RS02335	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BBI15_RS02340	COG1131	(ABC) transporter
BBI15_RS02360	COG0318	PFAM AMP-dependent synthetase and ligase
BBI15_RS02365	COG0655	NAD(P)H dehydrogenase (quinone) activity
BBI15_RS02375	COG4988	ABC transporter
BBI15_RS02380	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BBI15_RS02390	COG3239	Fatty acid desaturase
BBI15_RS02395	COG4585	Histidine kinase
BBI15_RS02400	COG2197	response regulator
BBI15_RS02405	COG4876	unkown
BBI15_RS02410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBI15_RS02415	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BBI15_RS02430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BBI15_RS02445	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBI15_RS02450	COG4605	iron ion homeostasis
BBI15_RS02455	COG4604	ABC transporter, ATP-binding protein
BBI15_RS02460	COG0671	phosphoesterase, PA-phosphatase related
BBI15_RS02465	COG0004	ammonium transporteR
BBI15_RS02470	COG0347	Belongs to the P(II) protein family
BBI15_RS02490	COG0477	Major facilitator Superfamily
BBI15_RS02505	COG1174	glycine betaine transport
BBI15_RS02510	COG1732	Glycine betaine
BBI15_RS02515	COG0183	Belongs to the thiolase family
BBI15_RS02535	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBI15_RS02540	COG0134	indole-3-glycerol-phosphate synthase activity
BBI15_RS02545	COG0133	tryptophan synthase activity
BBI15_RS02555	COG2094	Belongs to the DNA glycosylase MPG family
BBI15_RS02560	COG0693	protein deglycase activity
BBI15_RS02565	COG0640	Transcriptional regulator
BBI15_RS02570	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BBI15_RS02580	COG1227	inorganic diphosphatase activity
BBI15_RS02585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BBI15_RS02595	COG0723	plastoquinol--plastocyanin reductase activity
BBI15_RS02595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBI15_RS02600	COG2353	YceI-like domain
BBI15_RS02605	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BBI15_RS02620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BBI15_RS02625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BBI15_RS02665	COG2996	Protein conserved in bacteria
BBI15_RS02675	COG0346	lactoylglutathione lyase activity
BBI15_RS02695	COG2153	protein acetylation
BBI15_RS02710	COG1597	lipid kinase activity
BBI15_RS02730	COG2814	Major facilitator Superfamily
BBI15_RS02735	COG1876	peptidase activity
BBI15_RS02740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBI15_RS02755	COG0438	transferase activity, transferring glycosyl groups
BBI15_RS02760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBI15_RS02765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBI15_RS02780	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS02795	COG2217	Heavy metal translocating P-type atpase
BBI15_RS02800	COG2608	mercury ion transmembrane transporter activity
BBI15_RS02805	COG1937	Protein conserved in bacteria
BBI15_RS02810	COG0772	Belongs to the SEDS family
BBI15_RS02820	COG1181	Belongs to the D-alanine--D-alanine ligase family
BBI15_RS02825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBI15_RS02835	COG0513	Belongs to the DEAD box helicase family
BBI15_RS02840	COG3402	PFAM membrane-flanked domain
BBI15_RS02845	COG3428	Bacterial PH domain
BBI15_RS02850	COG0705	Rhomboid family
BBI15_RS02855	COG0736	holo-[acyl-carrier-protein] synthase activity
BBI15_RS02860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BBI15_RS02870	COG2337	Toxic component of a toxin-antitoxin (TA) module
BBI15_RS02875	COG1366	Belongs to the anti-sigma-factor antagonist family
BBI15_RS02880	COG1366	Belongs to the anti-sigma-factor antagonist family
BBI15_RS02885	COG2172	sigma factor antagonist activity
BBI15_RS02890	COG2208	phosphoserine phosphatase activity
BBI15_RS02895	COG1366	Belongs to the anti-sigma-factor antagonist family
BBI15_RS02900	COG2172	sigma factor antagonist activity
BBI15_RS02905	COG1191	sigma factor activity
BBI15_RS02910	COG2208	phosphoserine phosphatase activity
BBI15_RS02915	COG2183	response to ionizing radiation
BBI15_RS02920	COG3091	SprT-like family
BBI15_RS02985	COG0802	atpase or kinase
BBI15_RS02990	COG1214	PFAM Peptidase M22, glycoprotease
BBI15_RS02995	COG0456	acetyltransferase
BBI15_RS03000	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BBI15_RS03005	COG0488	(ABC) transporter
BBI15_RS03015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBI15_RS03020	COG0805	protein transport
BBI15_RS03025	COG1266	CAAX protease self-immunity
BBI15_RS03030	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BBI15_RS03035	COG0459	protein refolding
BBI15_RS03040	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS03045	COG1464	Belongs to the NlpA lipoprotein family
BBI15_RS03050	COG1960	acyl-CoA dehydrogenase activity
BBI15_RS03055	COG1307	EDD domain protein, DegV family
BBI15_RS03060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BBI15_RS03075	COG1309	transcriptional regulator
BBI15_RS03115	COG0646	methionine synthase
BBI15_RS03115	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BBI15_RS03120	COG1410	methionine synthase
BBI15_RS03120	COG0646	methionine synthase
BBI15_RS03125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBI15_RS03155	COG1388	LysM domain
BBI15_RS03180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBI15_RS03210	COG1396	sequence-specific DNA binding
BBI15_RS03215	COG0477	Major facilitator Superfamily
BBI15_RS03225	COG0300	oxidoreductase activity
BBI15_RS03230	COG1268	BioY protein
BBI15_RS03235	COG2169	Transcriptional regulator
BBI15_RS03240	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BBI15_RS03245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BBI15_RS03250	COG0110	maltose O-acetyltransferase activity
BBI15_RS03280	COG1609	Transcriptional regulator
BBI15_RS03285	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BBI15_RS03290	COG2610	gluconate transmembrane transporter activity
BBI15_RS03295	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBI15_RS03300	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS03310	COG1301	dicarboxylic acid transport
BBI15_RS03315	COG1090	epimerase
BBI15_RS03360	COG2814	Major facilitator Superfamily
BBI15_RS03365	COG0745	RESPONSE REGULATOR receiver
BBI15_RS03370	COG5002	protein histidine kinase activity
BBI15_RS03370	COG3850	Histidine kinase
BBI15_RS03380	COG1136	(ABC) transporter
BBI15_RS03430	COG1396	sequence-specific DNA binding
BBI15_RS03440	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
BBI15_RS03450	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BBI15_RS03520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBI15_RS03530	COG1902	pentaerythritol trinitrate reductase activity
BBI15_RS03545	COG1737	Transcriptional regulator
BBI15_RS03550	COG2133	pyrroloquinoline quinone binding
BBI15_RS03560	COG0535	radical SAM domain protein
BBI15_RS03590	COG2271	Major facilitator Superfamily
BBI15_RS03595	COG0277	FAD linked oxidase domain protein
BBI15_RS03640	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BBI15_RS03650	COG2318	DinB family
BBI15_RS03655	COG5505	Protein of unknown function (DUF819)
BBI15_RS03660	COG4129	membrane
BBI15_RS03665	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBI15_RS03680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BBI15_RS03685	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BBI15_RS03690	COG1126	abc transporter atp-binding protein
BBI15_RS03695	COG0765	amino acid transport
BBI15_RS03700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBI15_RS03720	COG1966	Carbon starvation protein
BBI15_RS03725	COG0673	inositol 2-dehydrogenase activity
BBI15_RS03735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBI15_RS03735	COG1263	PTS System
BBI15_RS03735	COG2190	(PTS) system
BBI15_RS03740	COG3711	transcriptional antiterminator
BBI15_RS03755	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BBI15_RS03760	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BBI15_RS03770	COG1233	COG1233 Phytoene dehydrogenase and related
BBI15_RS03775	COG2124	cytochrome p450
BBI15_RS03795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BBI15_RS03835	COG0596	Alpha beta hydrolase
BBI15_RS03845	COG2112	serine threonine protein kinase
BBI15_RS03855	COG5002	protein histidine kinase activity
BBI15_RS03875	COG3402	PFAM membrane-flanked domain
BBI15_RS03890	COG1695	Transcriptional regulator
BBI15_RS03895	COG0747	negative chemotaxis
BBI15_RS03905	COG1285	pathogenesis
BBI15_RS03915	COG3764	Sortase (surface protein transpeptidase)
BBI15_RS03945	COG0628	permease
BBI15_RS03950	COG2897	thiosulfate sulfurtransferase activity
BBI15_RS03960	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS03980	COG1368	sulfuric ester hydrolase activity
BBI15_RS03990	COG1473	amidohydrolase
BBI15_RS04000	COG4948	Mandelate Racemase Muconate Lactonizing
BBI15_RS04005	COG3949	Membrane
BBI15_RS04025	COG2851	Citrate transporter
BBI15_RS04035	COG3290	protein histidine kinase activity
BBI15_RS04045	COG1131	(ABC) transporter
BBI15_RS04050	COG2188	Transcriptional regulator
BBI15_RS04055	COG1104	cysteine desulfurase activity
BBI15_RS04060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BBI15_RS04065	COG0157	Belongs to the NadC ModD family
BBI15_RS04075	COG1454	alcohol dehydrogenase
BBI15_RS04080	COG2130	NADP-dependent
BBI15_RS04085	COG1902	pentaerythritol trinitrate reductase activity
BBI15_RS04100	COG0583	DNA-binding transcription factor activity
BBI15_RS04120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBI15_RS04125	COG0805	protein transport
BBI15_RS04130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBI15_RS04135	COG1757	Na H antiporter
BBI15_RS04145	COG3655	Transcriptional regulator
BBI15_RS04155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BBI15_RS04160	COG0022	dehydrogenase e1 component
BBI15_RS04165	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBI15_RS04170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBI15_RS04240	COG0305	Participates in initiation and elongation during chromosome replication
BBI15_RS04250	COG1528	Iron-storage protein
BBI15_RS04275	COG2356	endonuclease I
BBI15_RS04295	COG0300	oxidoreductase activity
BBI15_RS04310	COG1288	antiporter activity
BBI15_RS04315	COG1842	Phage shock protein A
BBI15_RS04320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BBI15_RS04330	COG4260	virion core protein, lumpy skin disease virus
BBI15_RS04335	COG1309	transcriptional regulator
BBI15_RS04350	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS04370	COG0318	PFAM AMP-dependent synthetase and ligase
BBI15_RS04375	COG4807	Protein conserved in bacteria
BBI15_RS04380	COG3588	fructose-bisphosphate aldolase
BBI15_RS04385	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS04390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBI15_RS04415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBI15_RS04420	COG0671	phosphoesterase, PA-phosphatase related
BBI15_RS04430	COG1366	Belongs to the anti-sigma-factor antagonist family
BBI15_RS04440	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS04450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBI15_RS04480	COG2326	polyphosphate kinase activity
BBI15_RS04485	COG2200	EAL domain
BBI15_RS04490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBI15_RS04500	COG2843	Capsule synthesis protein
BBI15_RS04525	COG1929	Belongs to the glycerate kinase type-1 family
BBI15_RS04535	COG0477	Major facilitator Superfamily
BBI15_RS04555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBI15_RS04560	COG1116	anion transmembrane transporter activity
BBI15_RS04565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BBI15_RS04570	COG0569	domain protein
BBI15_RS04595	COG0583	DNA-binding transcription factor activity
BBI15_RS04600	COG2610	gluconate transmembrane transporter activity
BBI15_RS04605	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS04610	COG2267	carboxylic ester hydrolase activity
BBI15_RS04615	COG0398	Pfam SNARE associated Golgi protein
BBI15_RS04625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BBI15_RS04630	COG1268	BioY protein
BBI15_RS04635	COG0366	Alpha amylase catalytic
BBI15_RS04640	COG1940	carbohydrate kinase activity
BBI15_RS04660	COG1609	Transcriptional regulator
BBI15_RS04665	COG0366	Alpha amylase catalytic
BBI15_RS04670	COG0166	Belongs to the GPI family
BBI15_RS04675	COG0768	penicillin binding
BBI15_RS04680	COG0366	Alpha amylase catalytic
BBI15_RS04695	COG0456	acetyltransferase
BBI15_RS04700	COG2508	Transcriptional regulator
BBI15_RS04705	COG0006	proline dipeptidase activity
BBI15_RS04715	COG1473	amidohydrolase
BBI15_RS04720	COG0460	homoserine dehydrogenase
BBI15_RS04725	COG1012	belongs to the aldehyde dehydrogenase family
BBI15_RS04730	COG0129	dihydroxy-acid dehydratase activity
BBI15_RS04735	COG0277	FAD linked oxidase domain protein
BBI15_RS04740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBI15_RS04745	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BBI15_RS04745	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BBI15_RS04750	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BBI15_RS04750	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BBI15_RS04755	COG0473	3-isopropylmalate dehydrogenase activity
BBI15_RS04760	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS04765	COG1012	belongs to the aldehyde dehydrogenase family
BBI15_RS04770	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BBI15_RS04780	COG0714	Associated with various cellular activities
BBI15_RS04785	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BBI15_RS04790	COG1305	Transglutaminase-like
BBI15_RS04795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BBI15_RS04795	COG0519	Catalyzes the synthesis of GMP from XMP
BBI15_RS04800	COG2252	PERMEase
BBI15_RS04820	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BBI15_RS04830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BBI15_RS04835	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BBI15_RS04840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBI15_RS04850	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBI15_RS04865	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BBI15_RS04875	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BBI15_RS04885	COG0151	Belongs to the GarS family
BBI15_RS04890	COG0456	acetyltransferase
BBI15_RS04895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BBI15_RS04900	COG1470	cell adhesion involved in biofilm formation
BBI15_RS04905	COG4496	protein, YerC YecD
BBI15_RS04915	COG0210	DNA helicase
BBI15_RS04925	COG4851	CamS sex pheromone cAM373 precursor
BBI15_RS04950	COG1597	lipid kinase activity
BBI15_RS04955	COG0494	nUDIX hydrolase
BBI15_RS04960	COG1271	oxidase subunit
BBI15_RS04965	COG1294	oxidase, subunit
BBI15_RS04970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBI15_RS04990	COG1309	transcriptional regulator
BBI15_RS04995	COG2814	Major facilitator Superfamily
BBI15_RS05005	COG2309	aminopeptidase activity
BBI15_RS05020	COG3859	Proton-coupled thiamine transporter YuaJ
BBI15_RS05025	COG0024	Methionine aminopeptidase
BBI15_RS05040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBI15_RS05045	COG2318	DinB family
BBI15_RS05050	COG0288	reversible hydration of carbon dioxide
BBI15_RS05055	COG1077	Cell shape determining protein MreB Mrl
BBI15_RS05060	COG2309	aminopeptidase activity
BBI15_RS05075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BBI15_RS05085	COG4840	Belongs to the UPF0435 family
BBI15_RS05100	COG1295	ribonuclease BN
BBI15_RS05105	COG2217	Heavy metal translocating P-type atpase
BBI15_RS05120	COG0477	Major facilitator Superfamily
BBI15_RS05125	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBI15_RS05130	COG1090	epimerase
BBI15_RS05150	COG1988	membrane-bound metal-dependent
BBI15_RS05155	COG1194	a g-specific adenine glycosylase
BBI15_RS05160	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS05165	COG3557	Belongs to the UPF0374 family
BBI15_RS05170	COG1132	(ABC) transporter
BBI15_RS05175	COG0444	Belongs to the ABC transporter superfamily
BBI15_RS05180	COG4608	Belongs to the ABC transporter superfamily
BBI15_RS05185	COG0747	negative chemotaxis
BBI15_RS05190	COG0601	transmembrane transport
BBI15_RS05195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBI15_RS05200	COG4129	membrane
BBI15_RS05210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BBI15_RS05215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBI15_RS05225	COG0735	belongs to the Fur family
BBI15_RS05350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBI15_RS05365	COG3382	B3 4 domain protein
BBI15_RS05370	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BBI15_RS05375	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BBI15_RS05385	COG2252	PERMEase
BBI15_RS05390	COG0656	L-ascorbic acid biosynthetic process
BBI15_RS05395	COG0564	pseudouridine synthase activity
BBI15_RS05405	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BBI15_RS05410	COG3153	acetyltransferase
BBI15_RS05410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBI15_RS05415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBI15_RS05420	COG4585	Histidine kinase
BBI15_RS05420	COG2203	Gaf domain
BBI15_RS05425	COG2197	response regulator
BBI15_RS05440	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BBI15_RS05440	COG3264	Mechanosensitive ion channel
BBI15_RS05450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BBI15_RS05455	COG1253	flavin adenine dinucleotide binding
BBI15_RS05465	COG3844	kynureninase activity
BBI15_RS05470	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BBI15_RS05490	COG1132	(ABC) transporter
BBI15_RS05495	COG1132	(ABC) transporter
BBI15_RS05515	COG1024	Enoyl-CoA hydratase
BBI15_RS05525	COG4152	abc transporter atp-binding protein
BBI15_RS05530	COG1668	transmembrane transport
BBI15_RS05535	COG0420	3'-5' exonuclease activity
BBI15_RS05545	COG3481	metal-dependent phosphohydrolase, HD sub domain
BBI15_RS05550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBI15_RS05580	COG0537	adenosine 5'-monophosphoramidase activity
BBI15_RS05585	COG1131	(ABC) transporter
BBI15_RS05590	COG4473	ABC transporter
BBI15_RS05595	COG1473	amidohydrolase
BBI15_RS05600	COG0530	calcium, potassium:sodium antiporter activity
BBI15_RS05605	COG2329	Antibiotic biosynthesis monooxygenase
BBI15_RS05610	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BBI15_RS05615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BBI15_RS05620	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BBI15_RS05635	COG0095	Lipoate-protein ligase
BBI15_RS05640	COG0745	RESPONSE REGULATOR receiver
BBI15_RS05645	COG2205	protein histidine kinase activity
BBI15_RS05650	COG1136	(ABC) transporter
BBI15_RS05660	COG0318	PFAM AMP-dependent synthetase and ligase
BBI15_RS05665	COG0823	Involved in the tonB-independent uptake of proteins
BBI15_RS05665	COG1506	peptidase
BBI15_RS05665	COG4946	Tricorn protease homolog
BBI15_RS05670	COG1024	Enoyl-CoA hydratase
BBI15_RS05675	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BBI15_RS05695	COG0556	nucleotide-excision repair
BBI15_RS05700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBI15_RS05705	COG3595	metallopeptidase activity
BBI15_RS05715	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BBI15_RS05725	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BBI15_RS05735	COG0110	maltose O-acetyltransferase activity
BBI15_RS05750	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BBI15_RS05755	COG0131	Imidazoleglycerol-phosphate dehydratase
BBI15_RS05760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BBI15_RS05765	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BBI15_RS05775	COG0140	phosphoribosyl-ATP diphosphatase activity
BBI15_RS05775	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BBI15_RS05780	COG0457	Tetratricopeptide repeat
BBI15_RS05785	COG0492	ferredoxin-NADP+ reductase activity
BBI15_RS05790	COG1051	belongs to the nudix hydrolase family
BBI15_RS05800	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BBI15_RS05810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBI15_RS05815	COG0740	serine-type endopeptidase activity
BBI15_RS05825	COG1704	LemA family
BBI15_RS05840	COG2390	Transcriptional regulator
BBI15_RS05870	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBI15_RS05875	COG1647	Serine aminopeptidase, S33
BBI15_RS05880	COG0557	exoribonuclease II activity
BBI15_RS05895	COG4974	Belongs to the 'phage' integrase family
BBI15_RS05925	COG1012	belongs to the aldehyde dehydrogenase family
BBI15_RS05930	COG4221	oxidoreductase activity
BBI15_RS05940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BBI15_RS05945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBI15_RS05960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBI15_RS05965	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBI15_RS05965	COG1024	Enoyl-CoA hydratase
BBI15_RS05970	COG0183	Belongs to the thiolase family
BBI15_RS05975	COG1960	acyl-CoA dehydrogenase activity
BBI15_RS05980	COG1393	Belongs to the ArsC family
BBI15_RS05990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BBI15_RS05995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBI15_RS06000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBI15_RS06010	COG1464	Belongs to the NlpA lipoprotein family
BBI15_RS06015	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BBI15_RS06025	COG0396	ATPase activity
BBI15_RS06030	COG0719	Fe-S assembly protein
BBI15_RS06035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BBI15_RS06040	COG0822	iron-sulfur transferase activity
BBI15_RS06045	COG0719	Fe-S assembly protein
BBI15_RS06060	COG0730	response to heat
BBI15_RS06075	COG0733	neurotransmitter:sodium symporter activity
BBI15_RS06080	COG4470	Protein conserved in bacteria
BBI15_RS06085	COG2445	Protein of unknown function DUF86
BBI15_RS06090	COG0647	UMP catabolic process
BBI15_RS06095	COG4844	belongs to the
BBI15_RS06100	COG1252	NADH dehydrogenase
BBI15_RS06105	COG4837	Protein of unknown function (DUF1462)
BBI15_RS06110	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BBI15_RS06115	COG0316	Belongs to the HesB IscA family
BBI15_RS06120	COG1252	NADH dehydrogenase
BBI15_RS06135	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BBI15_RS06140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BBI15_RS06145	COG1320	monovalent cation:proton antiporter activity
BBI15_RS06150	COG2212	antiporter activity
BBI15_RS06155	COG1863	multisubunit Na H antiporter MnhE subunit
BBI15_RS06160	COG0651	ATP synthesis coupled electron transport
BBI15_RS06165	COG1006	Multisubunit Na H antiporter MnhC subunit
BBI15_RS06170	COG2111	Na H antiporter
BBI15_RS06180	COG2814	Major facilitator Superfamily
BBI15_RS06185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BBI15_RS06190	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BBI15_RS06200	COG1396	sequence-specific DNA binding
BBI15_RS06205	COG0733	neurotransmitter:sodium symporter activity
BBI15_RS06215	COG1098	S1 RNA binding domain
BBI15_RS06220	COG3829	transcription factor binding
BBI15_RS06225	COG1012	belongs to the aldehyde dehydrogenase family
BBI15_RS06230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BBI15_RS06240	COG1979	alcohol dehydrogenase
BBI15_RS06250	COG1285	pathogenesis
BBI15_RS06370	COG0697	spore germination
BBI15_RS06375	COG1575	Belongs to the MenA family. Type 1 subfamily
BBI15_RS06380	COG1169	isochorismate synthase
BBI15_RS06390	COG0596	Alpha beta hydrolase
BBI15_RS06395	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BBI15_RS06400	COG0318	PFAM AMP-dependent synthetase and ligase
BBI15_RS06405	COG4948	Mandelate Racemase Muconate Lactonizing
BBI15_RS06410	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BBI15_RS06415	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BBI15_RS06420	COG0783	Belongs to the Dps family
BBI15_RS06425	COG0494	nUDIX hydrolase
BBI15_RS06430	COG1506	peptidase
BBI15_RS06445	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BBI15_RS06450	COG2267	carboxylic ester hydrolase activity
BBI15_RS06460	COG0028	Belongs to the TPP enzyme family
BBI15_RS06465	COG0604	alcohol dehydrogenase
BBI15_RS06470	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BBI15_RS06475	COG1242	4 iron, 4 sulfur cluster binding
BBI15_RS06480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BBI15_RS06485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BBI15_RS06495	COG2081	HI0933 family
BBI15_RS06500	COG2244	polysaccharide biosynthetic process
BBI15_RS06505	COG1187	pseudouridine synthase activity
BBI15_RS06510	COG1349	DNA-binding transcription factor activity
BBI15_RS06515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBI15_RS06540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBI15_RS06550	COG1363	Peptidase, m42
BBI15_RS06555	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BBI15_RS06565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBI15_RS06570	COG4848	Belongs to the UPF0354 family
BBI15_RS06575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBI15_RS06580	COG1674	ftsk spoiiie
BBI15_RS06590	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BBI15_RS06605	COG1605	Chorismate mutase
BBI15_RS06605	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BBI15_RS06615	COG0123	including yeast histone deacetylase and acetoin utilization protein
BBI15_RS06620	COG0517	IMP dehydrogenase activity
BBI15_RS06625	COG0454	-acetyltransferase
BBI15_RS06630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BBI15_RS06670	COG1956	GAF domain-containing protein
BBI15_RS06675	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBI15_RS06680	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BBI15_RS06685	COG1104	cysteine desulfurase activity
BBI15_RS06695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BBI15_RS06700	COG2962	Rard protein
BBI15_RS06705	COG0616	signal peptide processing
BBI15_RS06710	COG1714	RDD family
BBI15_RS06715	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BBI15_RS06720	COG0827	DNA restriction-modification system
BBI15_RS06725	COG0589	response to stress
BBI15_RS06730	COG2824	Alkylphosphonate utilization operon protein PhnA
BBI15_RS06740	COG0720	synthase
BBI15_RS06745	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BBI15_RS06750	COG0604	alcohol dehydrogenase
BBI15_RS06750	COG4221	oxidoreductase activity
BBI15_RS06750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BBI15_RS06750	COG3321	synthase
BBI15_RS06755	COG0589	response to stress
BBI15_RS06765	COG0006	proline dipeptidase activity
BBI15_RS06770	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BBI15_RS06775	COG4109	DRTGG domain
BBI15_RS06785	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BBI15_RS06790	COG0587	DNA-directed DNA polymerase activity
BBI15_RS06795	COG2186	Transcriptional regulator
BBI15_RS06805	COG0825	malonyl-CoA metabolic process
BBI15_RS06825	COG0372	Belongs to the citrate synthase family
BBI15_RS06830	COG0538	isocitrate dehydrogenase activity
BBI15_RS06835	COG0039	L-malate dehydrogenase activity
BBI15_RS06845	COG0745	RESPONSE REGULATOR receiver
BBI15_RS06850	COG5002	protein histidine kinase activity
BBI15_RS06865	COG0330	HflC and HflK could
BBI15_RS06870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBI15_RS06870	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBI15_RS06875	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BBI15_RS06885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BBI15_RS06890	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BBI15_RS06900	COG3611	Membrane attachment protein
BBI15_RS06905	COG1484	DNA-dependent DNA replication
BBI15_RS06910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BBI15_RS06915	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BBI15_RS06920	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BBI15_RS06945	COG1363	Peptidase, m42
BBI15_RS06955	COG1476	TRANSCRIPTIONal
BBI15_RS06970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBI15_RS06980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBI15_RS06980	COG0072	phenylalanine-tRNA ligase activity
BBI15_RS06995	COG1286	toxin biosynthetic process
BBI15_RS07000	COG1796	DNA polymerase
BBI15_RS07000	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBI15_RS07005	COG1193	negative regulation of DNA recombination
BBI15_RS07010	COG3766	membrane
BBI15_RS07015	COG0318	PFAM AMP-dependent synthetase and ligase
BBI15_RS07020	COG1309	transcriptional regulator
BBI15_RS07025	COG1024	Enoyl-CoA hydratase
BBI15_RS07030	COG2086	electron transfer activity
BBI15_RS07035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BBI15_RS07040	COG3118	belongs to the thioredoxin family
BBI15_RS07055	COG2009	succinate dehydrogenase
BBI15_RS07060	COG1053	succinate dehydrogenase
BBI15_RS07065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BBI15_RS07070	COG0824	Thioesterase
BBI15_RS07075	COG1846	Transcriptional regulator
BBI15_RS07110	COG1477	protein flavinylation
BBI15_RS07110	COG0457	Tetratricopeptide repeat
BBI15_RS07115	COG0544	peptidyl-prolyl cis-trans isomerase activity
BBI15_RS07130	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BBI15_RS07140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BBI15_RS07155	COG0113	porphobilinogen synthase activity
BBI15_RS07165	COG3180	Ammonia monooxygenase
BBI15_RS07170	COG0525	valine-tRNA ligase activity
BBI15_RS07175	COG0189	ligase activity
BBI15_RS07180	COG0189	ligase activity
BBI15_RS07190	COG2203	Gaf domain
BBI15_RS07190	COG2199	diguanylate cyclase activity
BBI15_RS07220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBI15_RS07230	COG1459	type II secretion system
BBI15_RS07255	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BBI15_RS07260	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BBI15_RS07265	COG0424	maF-like protein
BBI15_RS07270	COG2003	Belongs to the UPF0758 family
BBI15_RS07275	COG1077	Cell shape determining protein MreB Mrl
BBI15_RS07280	COG1792	Involved in formation and maintenance of cell shape
BBI15_RS07290	COG0850	regulation of cytokinetic process
BBI15_RS07295	COG2894	cell division
BBI15_RS07305	COG2868	ribosomal protein
BBI15_RS07310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BBI15_RS07330	COG0077	Prephenate dehydratase
BBI15_RS07335	COG1827	regulation of RNA biosynthetic process
BBI15_RS07360	COG1862	Preprotein translocase
BBI15_RS07370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBI15_RS07370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBI15_RS07375	COG5416	Lipopolysaccharide assembly protein A domain
BBI15_RS07380	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BBI15_RS07380	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BBI15_RS07385	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBI15_RS07390	COG5434	Belongs to the glycosyl hydrolase 28 family
BBI15_RS07395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BBI15_RS07405	COG3103	Sh3 type 3 domain protein
BBI15_RS07405	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBI15_RS07405	COG4991	sh3 domain protein
BBI15_RS07415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BBI15_RS07425	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BBI15_RS07430	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BBI15_RS07435	COG1959	2 iron, 2 sulfur cluster binding
BBI15_RS07440	COG1104	cysteine desulfurase activity
BBI15_RS07445	COG0482	sulfurtransferase activity
BBI15_RS07455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BBI15_RS07465	COG4472	Bacterial protein of unknown function (DUF965)
BBI15_RS07475	COG3906	Belongs to the UPF0473 family
BBI15_RS07480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BBI15_RS07485	COG4122	O-methyltransferase activity
BBI15_RS07490	COG0572	uridine kinase
BBI15_RS07495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BBI15_RS07510	COG1183	phosphatidylcholine synthase activity
BBI15_RS07515	COG0688	phosphatidylethanolamine metabolic process
BBI15_RS07520	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BBI15_RS07525	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BBI15_RS07535	COG1534	Rna-binding protein
BBI15_RS07540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBI15_RS07545	COG1713	HD superfamily hydrolase involved in NAD metabolism
BBI15_RS07550	COG0799	negative regulation of ribosome biogenesis
BBI15_RS07555	COG2226	methyltransferase
BBI15_RS07560	COG1596	polysaccharide export
BBI15_RS07560	COG1555	photosystem II stabilization
BBI15_RS07565	COG2131	deaminase
BBI15_RS07570	COG2333	competence protein COMEC
BBI15_RS07570	COG0658	competence protein
BBI15_RS07575	COG1466	dna polymerase III delta subunit
BBI15_RS07585	COG0481	GTPase activity
BBI15_RS07590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBI15_RS07600	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BBI15_RS07605	COG0443	Heat shock 70 kDa protein
BBI15_RS07615	COG2264	protein methyltransferase activity
BBI15_RS07620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BBI15_RS07625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBI15_RS07630	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBI15_RS07635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BBI15_RS07640	COG1030	water channel activity
BBI15_RS07645	COG4864	UPF0365 protein
BBI15_RS07655	COG1702	phosphate starvation-inducible protein PhoH
BBI15_RS07660	COG1480	7TM receptor with intracellular HD hydrolase
BBI15_RS07670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BBI15_RS07685	COG1381	Involved in DNA repair and RecF pathway recombination
BBI15_RS07695	COG0517	IMP dehydrogenase activity
BBI15_RS07705	COG0358	DNA primase activity
BBI15_RS07710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBI15_RS07715	COG1960	acyl-CoA dehydrogenase activity
BBI15_RS07725	COG2384	SAM-dependent methyltransferase
BBI15_RS07730	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BBI15_RS07740	COG0513	Belongs to the DEAD box helicase family
BBI15_RS07750	COG1121	(ABC) transporter
BBI15_RS07755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBI15_RS07760	COG0735	belongs to the Fur family
BBI15_RS07765	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BBI15_RS07770	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BBI15_RS07780	COG1283	sodium-dependent phosphate transmembrane transporter activity
BBI15_RS07795	COG0768	penicillin binding
BBI15_RS07800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BBI15_RS07805	COG0573	inorganic phosphate transmembrane transporter activity
BBI15_RS07810	COG0581	inorganic phosphate transmembrane transporter activity
BBI15_RS07815	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BBI15_RS07820	COG0704	Plays a role in the regulation of phosphate uptake
BBI15_RS07825	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BBI15_RS07830	COG4483	Protein conserved in bacteria
BBI15_RS07835	COG1368	sulfuric ester hydrolase activity
BBI15_RS07845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBI15_RS07855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBI15_RS07860	COG1459	type II secretion system
BBI15_RS07890	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BBI15_RS07895	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BBI15_RS07910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBI15_RS07915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBI15_RS07920	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BBI15_RS07925	COG0006	proline dipeptidase activity
BBI15_RS07930	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BBI15_RS07935	COG0511	ligase activity, forming carbon-carbon bonds
BBI15_RS07940	COG0439	Biotin carboxylase
BBI15_RS07945	COG1302	Protein conserved in bacteria
BBI15_RS07955	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BBI15_RS07970	COG0142	geranyltranstransferase activity
BBI15_RS07975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BBI15_RS07980	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BBI15_RS07985	COG1438	arginine binding
BBI15_RS07990	COG0497	DNA recombination
BBI15_RS08000	COG0584	glycerophosphoryl diester phosphodiesterase
BBI15_RS08010	COG3829	transcription factor binding
BBI15_RS08010	COG3290	protein histidine kinase activity
BBI15_RS08015	COG0280	phosphate acetyltransferase
BBI15_RS08025	COG3426	butyrate kinase activity
BBI15_RS08030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBI15_RS08035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BBI15_RS08040	COG0022	dehydrogenase e1 component
BBI15_RS08045	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBI15_RS08050	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBI15_RS08055	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBI15_RS08055	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBI15_RS08070	COG4129	membrane
BBI15_RS08075	COG0346	lactoylglutathione lyase activity
BBI15_RS08080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BBI15_RS08085	COG2195	Cleaves the N-terminal amino acid of tripeptides
BBI15_RS08090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBI15_RS08095	COG1234	tRNA 3'-trailer cleavage
BBI15_RS08110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBI15_RS08170	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BBI15_RS08180	COG0789	Transcriptional regulator
BBI15_RS08185	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BBI15_RS08195	COG2133	pyrroloquinoline quinone binding
BBI15_RS08230	COG0778	Nitroreductase
BBI15_RS08235	COG1846	Transcriptional regulator
BBI15_RS08240	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BBI15_RS08245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBI15_RS08250	COG0011	TIGRFAM Protein of
BBI15_RS08255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBI15_RS08270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBI15_RS08275	COG1737	Transcriptional regulator
BBI15_RS08280	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BBI15_RS08285	COG2610	gluconate transmembrane transporter activity
BBI15_RS08290	COG1070	Carbohydrate kinase
BBI15_RS08300	COG0494	nUDIX hydrolase
BBI15_RS08310	COG2304	oxidoreductase activity
BBI15_RS08340	COG0398	Pfam SNARE associated Golgi protein
BBI15_RS08360	COG3842	ATPase activity
BBI15_RS08365	COG1902	pentaerythritol trinitrate reductase activity
BBI15_RS08370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BBI15_RS08375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBI15_RS08385	COG0137	argininosuccinate synthase activity
BBI15_RS08390	COG0165	Argininosuccinate lyase
BBI15_RS08395	COG0785	Cytochrome C biogenesis protein
BBI15_RS08400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBI15_RS08405	COG4846	Membrane protein involved in cytochrome C biogenesis
BBI15_RS08425	COG1999	signal sequence binding
BBI15_RS08445	COG1335	isochorismatase
BBI15_RS08460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BBI15_RS08465	COG0824	Thioesterase
BBI15_RS08475	COG4841	protein insertion into membrane
BBI15_RS08480	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BBI15_RS08485	COG1832	CoA-binding protein
BBI15_RS08490	COG0187	DNA topoisomerase II activity
BBI15_RS08495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBI15_RS08500	COG0318	PFAM AMP-dependent synthetase and ligase
BBI15_RS08515	COG2391	methyltransferase activity
BBI15_RS08525	COG0697	spore germination
BBI15_RS08530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BBI15_RS08555	COG0406	alpha-ribazole phosphatase activity
BBI15_RS08580	COG1105	Belongs to the carbohydrate kinase PfkB family
BBI15_RS08585	COG1349	DNA-binding transcription factor activity
BBI15_RS08595	COG0300	oxidoreductase activity
BBI15_RS08610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BBI15_RS08615	COG3258	Cytochrome c
BBI15_RS08630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBI15_RS08685	COG0071	Belongs to the small heat shock protein (HSP20) family
BBI15_RS08695	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BBI15_RS08715	COG1473	amidohydrolase
BBI15_RS08725	COG0372	Belongs to the citrate synthase family
BBI15_RS08730	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BBI15_RS08745	COG0628	permease
BBI15_RS08755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBI15_RS08765	COG2807	transmembrane transport
BBI15_RS08775	COG0488	(ABC) transporter
BBI15_RS08785	COG1278	Cold shock
BBI15_RS08790	COG1278	Cold shock
BBI15_RS08800	COG3853	Toxic anion resistance protein (TelA)
BBI15_RS08805	COG4548	von Willebrand factor, type A
BBI15_RS08810	COG0714	Associated with various cellular activities
BBI15_RS08830	COG0567	Dehydrogenase, E1 component
BBI15_RS08835	COG5001	Diguanylate cyclase
BBI15_RS08835	COG3447	MASE1 domain protein
BBI15_RS08835	COG5002	protein histidine kinase activity
BBI15_RS08840	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BBI15_RS08860	COG0523	cobalamin synthesis protein
BBI15_RS08865	COG3409	Peptidoglycan-binding domain 1 protein
BBI15_RS08865	COG0793	Belongs to the peptidase S41A family
BBI15_RS08870	COG0813	purine-nucleoside phosphorylase activity
BBI15_RS08875	COG4479	Belongs to the UPF0346 family
BBI15_RS08895	COG2755	lipolytic protein G-D-S-L family
BBI15_RS08900	COG1307	EDD domain protein, DegV family
BBI15_RS08910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BBI15_RS08925	COG2521	methyltransferase
BBI15_RS08925	COG2136	Putative SAM-dependent methyltransferase
BBI15_RS08950	COG1413	lyase activity
BBI15_RS08955	COG0488	(ABC) transporter
BBI15_RS08960	COG1418	mRNA catabolic process
BBI15_RS08975	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BBI15_RS08995	COG2133	pyrroloquinoline quinone binding
BBI15_RS09015	COG0702	epimerase
BBI15_RS09030	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS09035	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BBI15_RS09040	COG1253	flavin adenine dinucleotide binding
BBI15_RS09050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BBI15_RS09055	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS09060	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BBI15_RS09065	COG1199	ATP-dependent helicase activity
BBI15_RS09070	COG0116	Belongs to the methyltransferase superfamily
BBI15_RS09085	COG3599	regulation of cell shape
BBI15_RS09090	COG3359	exonuclease
BBI15_RS09095	COG1111	helicase
BBI15_RS09095	COG1205	dead DEAH box helicase
BBI15_RS09110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBI15_RS09110	COG4499	WXG100 protein secretion system (Wss), protein YukC
BBI15_RS09120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BBI15_RS09125	COG3935	DnaD domain protein
BBI15_RS09150	COG1199	ATP-dependent helicase activity
BBI15_RS09150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BBI15_RS09155	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BBI15_RS09175	COG0438	transferase activity, transferring glycosyl groups
BBI15_RS09190	COG1694	Mazg nucleotide pyrophosphohydrolase
BBI15_RS09195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBI15_RS09200	COG2738	Putative neutral zinc metallopeptidase
BBI15_RS09205	COG4347	Protein of unknown function (DUF1405)
BBI15_RS09220	COG0723	plastoquinol--plastocyanin reductase activity
BBI15_RS09235	COG0457	Tetratricopeptide repeat
BBI15_RS09245	COG0287	Prephenate dehydrogenase
BBI15_RS09250	COG4401	Chorismate mutase type I
BBI15_RS09265	COG0105	UTP biosynthetic process
BBI15_RS09270	COG0142	geranyltranstransferase activity
BBI15_RS09280	COG0142	geranyltranstransferase activity
BBI15_RS09320	COG1304	FMN binding
BBI15_RS09325	COG0539	negative regulation of cytoplasmic translation
BBI15_RS09330	COG0204	Acyl-transferase
BBI15_RS09340	COG2339	peptidase activity
BBI15_RS09350	COG0492	ferredoxin-NADP+ reductase activity
BBI15_RS09355	COG1408	metallophosphoesterase
BBI15_RS09365	COG1388	LysM domain
BBI15_RS09370	COG0514	ATP-dependent DNA helicase (RecQ)
BBI15_RS09375	COG4955	Helix-turn-helix domain
BBI15_RS09380	COG1141	Ferredoxin
BBI15_RS09385	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BBI15_RS09395	COG1595	DNA-templated transcription, initiation
BBI15_RS09400	COG5002	protein histidine kinase activity
BBI15_RS09405	COG0745	RESPONSE REGULATOR receiver
BBI15_RS09410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BBI15_RS09415	COG1333	cytochrome c biogenesis protein
BBI15_RS09420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBI15_RS09425	COG1187	pseudouridine synthase activity
BBI15_RS09430	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBI15_RS09440	COG1547	Domain of unknown function (DUF309)
BBI15_RS09450	COG0019	diaminopimelate decarboxylase activity
BBI15_RS09465	COG4974	Belongs to the 'phage' integrase family
BBI15_RS09470	COG0735	belongs to the Fur family
BBI15_RS09475	COG0494	nUDIX hydrolase
BBI15_RS09480	COG0667	Aldo Keto reductase
BBI15_RS09490	COG2268	Band 7 protein
BBI15_RS09505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBI15_RS09510	COG1073	alpha beta
BBI15_RS09515	COG3763	UPF0154 protein
BBI15_RS09530	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BBI15_RS09535	COG1388	LysM domain
BBI15_RS09555	COG0174	glutamine synthetase
BBI15_RS09560	COG0789	Transcriptional regulator
BBI15_RS09565	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BBI15_RS09570	COG2860	membrane
BBI15_RS09575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBI15_RS09580	COG1923	regulation of RNA biosynthetic process
BBI15_RS09605	COG4550	Control of competence regulator ComK, YlbF/YmcA
BBI15_RS09610	COG1692	metallophosphoesterase
BBI15_RS09620	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BBI15_RS09630	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBI15_RS09635	COG1426	Protein conserved in bacteria
BBI15_RS09650	COG0612	Peptidase, M16
BBI15_RS09655	COG0612	Peptidase, M16
BBI15_RS09660	COG1079	Belongs to the binding-protein-dependent transport system permease family
BBI15_RS09665	COG4603	Belongs to the binding-protein-dependent transport system permease family
BBI15_RS09670	COG3845	ABC transporter
BBI15_RS09675	COG1744	ABC transporter substrate-binding protein PnrA-like
BBI15_RS09680	COG2188	Transcriptional regulator
BBI15_RS09685	COG1674	ftsk spoiiie
BBI15_RS09690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBI15_RS09695	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BBI15_RS09700	COG0612	Peptidase, M16
BBI15_RS09710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BBI15_RS09715	COG0196	riboflavin kinase activity
BBI15_RS09725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BBI15_RS09730	COG1550	Protein conserved in bacteria
BBI15_RS09740	COG1358	cellular component organization or biogenesis
BBI15_RS09745	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BBI15_RS09750	COG0195	Participates in both transcription termination and antitermination
BBI15_RS09760	COG2176	DNA-directed DNA polymerase activity
BBI15_RS09770	COG0750	zinc metalloprotease
BBI15_RS09780	COG4589	Belongs to the CDS family
BBI15_RS09785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BBI15_RS09790	COG0233	cytoplasmic translational termination
BBI15_RS09795	COG0528	UMP kinase activity
BBI15_RS09810	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BBI15_RS09815	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BBI15_RS09820	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BBI15_RS09825	COG4974	Belongs to the 'phage' integrase family
BBI15_RS09835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBI15_RS09840	COG0758	DNA mediated transformation
BBI15_RS09850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BBI15_RS09860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BBI15_RS09865	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BBI15_RS09880	COG0336	Belongs to the RNA methyltransferase TrmD family
BBI15_RS09885	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BBI15_RS09890	COG1837	Belongs to the UPF0109 family
BBI15_RS09900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BBI15_RS09905	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BBI15_RS09910	COG0552	protein localization to endoplasmic reticulum
BBI15_RS09920	COG0571	ribonuclease III activity
BBI15_RS09925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBI15_RS09930	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS09935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BBI15_RS09945	COG2050	protein possibly involved in aromatic compounds catabolism
BBI15_RS09945	COG1349	DNA-binding transcription factor activity
BBI15_RS09950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BBI15_RS09955	COG1760	l-serine dehydratase
BBI15_RS09960	COG1760	l-serine dehydratase
BBI15_RS09965	COG1461	Dihydroxyacetone kinase
BBI15_RS09970	COG1302	Protein conserved in bacteria
BBI15_RS09975	COG1564	THIamine pyrophosphokinase
BBI15_RS09980	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBI15_RS09985	COG1162	GTPase activity
BBI15_RS09990	COG2815	serine threonine protein kinase
BBI15_RS09990	COG0515	serine threonine protein kinase
BBI15_RS09995	COG0631	protein serine/threonine phosphatase activity
BBI15_RS10000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBI15_RS10000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBI15_RS10015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BBI15_RS10020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BBI15_RS10030	COG0194	GDP metabolic process
BBI15_RS10035	COG2052	Domain of unknown function (DUF370)
BBI15_RS10040	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BBI15_RS10045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBI15_RS10050	COG0765	amino acid transport
BBI15_RS10065	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BBI15_RS10075	COG0167	dihydroorotate dehydrogenase activity
BBI15_RS10090	COG0505	Belongs to the CarA family
BBI15_RS10095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBI15_RS10110	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BBI15_RS10115	COG0564	pseudouridine synthase activity
BBI15_RS10120	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BBI15_RS10125	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BBI15_RS10130	COG3599	regulation of cell shape
BBI15_RS10135	COG2302	S4 RNA-binding domain
BBI15_RS10140	COG0762	integral membrane protein
BBI15_RS10145	COG1799	cell septum assembly
BBI15_RS10150	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BBI15_RS10155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BBI15_RS10160	COG0849	cell division
BBI15_RS10165	COG3856	small basic protein
BBI15_RS10170	COG3879	Bacterial protein of unknown function (DUF881)
BBI15_RS10175	COG3879	Bacterial protein of unknown function (DUF881)
BBI15_RS10180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BBI15_RS10185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBI15_RS10195	COG0768	penicillin binding
BBI15_RS10210	COG2001	Belongs to the MraZ family
BBI15_RS10225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BBI15_RS10230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BBI15_RS10235	COG0511	ligase activity, forming carbon-carbon bonds
BBI15_RS10240	COG0439	Biotin carboxylase
BBI15_RS10245	COG1024	Enoyl-CoA hydratase
BBI15_RS10250	COG1399	metal-binding, possibly nucleic acid-binding protein
BBI15_RS10260	COG3480	Lon protease (S16) C-terminal proteolytic domain
BBI15_RS10265	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BBI15_RS10270	COG0742	ribosomal rna small subunit methyltransferase
BBI15_RS10280	COG4471	UPF0298 protein
BBI15_RS10285	COG0584	glycerophosphoryl diester phosphodiesterase
BBI15_RS10290	COG3679	Belongs to the UPF0342 family
BBI15_RS10295	COG2340	Cysteine-rich secretory protein family
BBI15_RS10315	COG3336	cytochrome c oxidase
BBI15_RS10320	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BBI15_RS10350	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BBI15_RS10355	COG0772	Belongs to the SEDS family
BBI15_RS10365	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BBI15_RS10370	COG4896	Protein conserved in bacteria
BBI15_RS10385	COG1217	gtp-binding protein TYPA
BBI15_RS10395	COG0483	inositol monophosphate 1-phosphatase activity
BBI15_RS10420	COG1982	Orn Lys Arg decarboxylase major
BBI15_RS10425	COG0726	polysaccharide deacetylase
BBI15_RS10435	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBI15_RS10440	COG0022	dehydrogenase e1 component
BBI15_RS10460	COG0561	phosphatase activity
BBI15_RS10470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBI15_RS10475	COG0569	domain protein
BBI15_RS10490	COG3842	ATPase activity
BBI15_RS10495	COG1176	ABC-type spermidine putrescine transport system, permease component I
BBI15_RS10500	COG1177	transmembrane transport
BBI15_RS10505	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BBI15_RS10510	COG2814	Major facilitator Superfamily
BBI15_RS10515	COG1473	amidohydrolase
BBI15_RS10520	COG2171	N-acyltransferase activity
BBI15_RS10525	COG0583	DNA-binding transcription factor activity
BBI15_RS10530	COG0477	Major facilitator Superfamily
BBI15_RS10535	COG0517	IMP dehydrogenase activity
BBI15_RS10540	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS10550	COG2084	Dehydrogenase
BBI15_RS10575	COG1846	Transcriptional regulator
BBI15_RS10580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBI15_RS10590	COG1191	sigma factor activity
BBI15_RS10595	COG0861	Integral membrane protein TerC family
BBI15_RS10610	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BBI15_RS10615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBI15_RS10620	COG1363	Peptidase, m42
BBI15_RS10625	COG4191	Histidine kinase
BBI15_RS10640	COG3850	Histidine kinase
BBI15_RS10640	COG5002	protein histidine kinase activity
BBI15_RS10645	COG0745	RESPONSE REGULATOR receiver
BBI15_RS10655	COG0673	inositol 2-dehydrogenase activity
BBI15_RS10660	COG1525	nuclease
BBI15_RS10685	COG2358	TRAP transporter, solute receptor (TAXI family
BBI15_RS10690	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BBI15_RS10695	COG2382	esterase
BBI15_RS10700	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BBI15_RS10710	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BBI15_RS10715	COG2239	Acts as a magnesium transporter
BBI15_RS10720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BBI15_RS10725	COG0564	pseudouridine synthase activity
BBI15_RS10735	COG2357	RelA SpoT domain protein
BBI15_RS10740	COG4116	CYTH
BBI15_RS10745	COG2346	COG2346, Truncated hemoglobins
BBI15_RS10750	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BBI15_RS10755	COG1164	Oligoendopeptidase f
BBI15_RS10765	COG4862	establishment of competence for transformation
BBI15_RS10770	COG1393	Belongs to the ArsC family
BBI15_RS10780	COG4608	Belongs to the ABC transporter superfamily
BBI15_RS10785	COG0444	Belongs to the ABC transporter superfamily
BBI15_RS10790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBI15_RS10795	COG0601	transmembrane transport
BBI15_RS10810	COG0180	Tryptophanyl-tRNA synthetase
BBI15_RS10815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBI15_RS10820	COG0601	transmembrane transport
BBI15_RS10830	COG4608	Belongs to the ABC transporter superfamily
BBI15_RS10840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BBI15_RS10860	COG2151	metal-sulfur cluster biosynthetic enzyme
BBI15_RS10865	COG1073	alpha beta
BBI15_RS10870	COG0561	phosphatase activity
BBI15_RS10875	COG1307	EDD domain protein, DegV family
BBI15_RS10895	COG0179	Fumarylacetoacetate (FAA) hydrolase
BBI15_RS10900	COG2311	Membrane
BBI15_RS10915	COG0398	Pfam SNARE associated Golgi protein
BBI15_RS10920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BBI15_RS10930	COG4897	Protein conserved in bacteria
BBI15_RS10935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBI15_RS10940	COG0626	cystathionine gamma-synthase activity
BBI15_RS10945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBI15_RS10950	COG0739	heme binding
BBI15_RS10955	COG2177	Part of the ABC transporter FtsEX involved in
BBI15_RS10960	COG2884	Cell division ATP-binding protein ftsE
BBI15_RS10970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBI15_RS10980	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BBI15_RS10985	COG0653	protein targeting
BBI15_RS10990	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BBI15_RS10995	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS11000	COG1040	competence protein
BBI15_RS11005	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BBI15_RS11010	COG1307	EDD domain protein, DegV family
BBI15_RS11020	COG2176	DNA-directed DNA polymerase activity
BBI15_RS11025	COG2197	response regulator
BBI15_RS11030	COG4585	Histidine kinase
BBI15_RS11035	COG1739	Uncharacterized protein family UPF0029
BBI15_RS11040	COG1316	TRANSCRIPTIONal
BBI15_RS11045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBI15_RS11060	COG1114	Component of the transport system for branched-chain amino acids
BBI15_RS11085	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BBI15_RS11120	COG1473	amidohydrolase
BBI15_RS11130	COG1012	belongs to the aldehyde dehydrogenase family
BBI15_RS11135	COG0083	homoserine kinase activity
BBI15_RS11140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BBI15_RS11145	COG0460	homoserine dehydrogenase
BBI15_RS11150	COG0527	aspartate kinase activity
BBI15_RS11155	COG4297	protein containing double-stranded beta helix domain
BBI15_RS11160	COG4187	Peptidase family M20/M25/M40
BBI15_RS11165	COG0436	Aminotransferase
BBI15_RS11170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BBI15_RS11170	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BBI15_RS11180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBI15_RS11185	COG1802	Transcriptional regulator
BBI15_RS11190	COG0277	FAD linked oxidase domain protein
BBI15_RS11195	COG1388	LysM domain
BBI15_RS11195	COG0791	NLP P60 protein
BBI15_RS11215	COG2224	Isocitrate lyase
BBI15_RS11220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BBI15_RS11250	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BBI15_RS11255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBI15_RS11260	COG0765	amino acid transport
BBI15_RS11265	COG1126	abc transporter atp-binding protein
BBI15_RS11285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBI15_RS11315	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BBI15_RS11320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBI15_RS11325	COG0640	Transcriptional regulator
BBI15_RS11355	COG0626	cystathionine gamma-synthase activity
BBI15_RS11360	COG0626	cystathionine gamma-synthase activity
BBI15_RS11365	COG0281	malic enzyme
BBI15_RS11370	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBI15_RS11400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BBI15_RS11415	COG0489	protein tyrosine kinase activity
BBI15_RS11420	COG3944	biosynthesis protein
BBI15_RS11430	COG0745	RESPONSE REGULATOR receiver
BBI15_RS11435	COG5002	protein histidine kinase activity
BBI15_RS11440	COG5001	Diguanylate cyclase
BBI15_RS11485	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BBI15_RS11495	COG5298	Protein conserved in bacteria
BBI15_RS11500	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BBI15_RS11520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BBI15_RS11530	COG3764	Sortase (surface protein transpeptidase)
BBI15_RS11535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBI15_RS11545	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BBI15_RS11555	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BBI15_RS11560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BBI15_RS11565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BBI15_RS11570	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BBI15_RS11575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBI15_RS11585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BBI15_RS11620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BBI15_RS11635	COG0728	peptidoglycan biosynthetic process
BBI15_RS11655	COG2329	Antibiotic biosynthesis monooxygenase
BBI15_RS11715	COG1522	sequence-specific DNA binding
BBI15_RS11720	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BBI15_RS11735	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BBI15_RS11740	COG1368	sulfuric ester hydrolase activity
BBI15_RS11750	COG3706	GGDEF domain
BBI15_RS11785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BBI15_RS11805	COG0686	Belongs to the AlaDH PNT family
BBI15_RS11815	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BBI15_RS11820	COG0363	glucosamine-6-phosphate deaminase activity
BBI15_RS11825	COG1393	Belongs to the ArsC family
BBI15_RS11845	COG0246	Mannitol dehydrogenase
BBI15_RS11850	COG3711	transcriptional antiterminator
BBI15_RS11855	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBI15_RS11855	COG2213	PTS system mannitol-specific
BBI15_RS11860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBI15_RS11900	COG1115	amino acid carrier protein
BBI15_RS11980	COG1131	(ABC) transporter
BBI15_RS11990	COG1131	(ABC) transporter
BBI15_RS12015	COG0765	amino acid transport
BBI15_RS12020	COG0765	amino acid transport
BBI15_RS12025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBI15_RS12030	COG1126	abc transporter atp-binding protein
BBI15_RS12050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BBI15_RS12055	COG0110	maltose O-acetyltransferase activity
BBI15_RS12060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BBI15_RS12065	COG0438	transferase activity, transferring glycosyl groups
BBI15_RS12110	COG0489	protein tyrosine kinase activity
BBI15_RS12115	COG3944	biosynthesis protein
BBI15_RS12125	COG1316	TRANSCRIPTIONal
BBI15_RS12145	COG1088	dTDP-glucose 4,6-dehydratase activity
BBI15_RS12155	COG0737	Belongs to the 5'-nucleotidase family
BBI15_RS12175	COG3621	Patatin-like phospholipase
BBI15_RS12180	COG0791	NLP P60 protein
BBI15_RS12180	COG1388	LysM domain
BBI15_RS12225	COG0596	Alpha beta hydrolase
BBI15_RS12245	COG0745	RESPONSE REGULATOR receiver
BBI15_RS12250	COG5002	protein histidine kinase activity
BBI15_RS12255	COG1388	LysM domain
BBI15_RS12295	COG2364	Membrane
BBI15_RS12300	COG1846	Transcriptional regulator
BBI15_RS12305	COG0456	acetyltransferase
BBI15_RS12315	COG2076	Multidrug Resistance protein
BBI15_RS12320	COG2076	Multidrug Resistance protein
BBI15_RS12325	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBI15_RS12340	COG1621	beta-fructofuranosidase activity
BBI15_RS12370	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBI15_RS12405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBI15_RS12415	COG1366	Belongs to the anti-sigma-factor antagonist family
BBI15_RS12425	COG2226	methyltransferase
BBI15_RS12450	COG0352	thiamine-phosphate diphosphorylase activity
BBI15_RS12455	COG0351	phosphomethylpyrimidine kinase
BBI15_RS12460	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BBI15_RS12465	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BBI15_RS12485	COG0728	peptidoglycan biosynthetic process
BBI15_RS12490	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BBI15_RS12510	COG0737	Belongs to the 5'-nucleotidase family
BBI15_RS12525	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBI15_RS12530	COG1368	sulfuric ester hydrolase activity
BBI15_RS12540	COG2385	sporulation resulting in formation of a cellular spore
BBI15_RS12545	COG0791	NLP P60 protein
BBI15_RS12545	COG1388	LysM domain
BBI15_RS12550	COG0438	transferase activity, transferring glycosyl groups
BBI15_RS12555	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BBI15_RS12560	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BBI15_RS12565	COG1115	amino acid carrier protein
BBI15_RS12570	COG1473	amidohydrolase
BBI15_RS12575	COG4187	Peptidase family M20/M25/M40
BBI15_RS12610	COG4608	Belongs to the ABC transporter superfamily
BBI15_RS12615	COG0791	NLP P60 protein
BBI15_RS12620	COG4948	Mandelate Racemase Muconate Lactonizing
BBI15_RS12625	COG1619	proteins homologs of microcin C7 resistance protein MccF
BBI15_RS12630	COG4166	transmembrane transport
BBI15_RS12635	COG0444	Belongs to the ABC transporter superfamily
BBI15_RS12645	COG0601	transmembrane transport
BBI15_RS12650	COG2362	D-Aminopeptidase
BBI15_RS12660	COG4715	Zinc finger, swim domain protein
BBI15_RS12665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBI15_RS12670	COG0629	single-stranded DNA binding
BBI15_RS12690	COG1077	Cell shape determining protein MreB Mrl
BBI15_RS12700	COG4836	Membrane
BBI15_RS12735	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BBI15_RS12760	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BBI15_RS12765	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BBI15_RS12780	COG4475	Protein of unknown function (DUF436)
BBI15_RS12785	COG0698	ribose 5-phosphate isomerase
BBI15_RS12790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBI15_RS12795	COG0009	L-threonylcarbamoyladenylate synthase
BBI15_RS12805	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BBI15_RS12810	COG1435	thymidine kinase activity
BBI15_RS12815	COG0254	rRNA binding
BBI15_RS12820	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BBI15_RS12825	COG1494	fructose-1,6-bisphosphatase
BBI15_RS12830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBI15_RS12845	COG2204	response regulator
BBI15_RS12850	COG4821	SIS domain
BBI15_RS12865	COG1703	isobutyryl-CoA mutase activity
BBI15_RS12865	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBI15_RS12865	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBI15_RS12875	COG1960	acyl-CoA dehydrogenase activity
BBI15_RS12880	COG1960	acyl-CoA dehydrogenase activity
BBI15_RS12885	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBI15_RS12890	COG0183	Belongs to the thiolase family
BBI15_RS12895	COG0247	lactate metabolic process
BBI15_RS12895	COG2181	nitrate reductase activity
BBI15_RS12925	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BBI15_RS12940	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BBI15_RS12945	COG1120	ATPase activity
BBI15_RS12950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBI15_RS12955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBI15_RS12960	COG0018	arginyl-trna synthetase
BBI15_RS12970	COG0010	Belongs to the arginase family
BBI15_RS12975	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BBI15_RS12990	COG3465	dGTPase activity
BBI15_RS12995	COG1078	dGTPase activity
BBI15_RS13005	COG3253	May function as heme-dependent peroxidase
BBI15_RS13020	COG2363	Small membrane protein
BBI15_RS13055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BBI15_RS13060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BBI15_RS13065	COG3314	Sporulation integral membrane protein YlbJ
BBI15_RS13070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BBI15_RS13075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBI15_RS13080	COG0765	amino acid transport
BBI15_RS13085	COG1126	abc transporter atp-binding protein
BBI15_RS13090	COG1288	antiporter activity
BBI15_RS13100	COG1473	amidohydrolase
BBI15_RS13105	COG0156	8-amino-7-oxononanoate synthase activity
BBI15_RS13110	COG1511	domain protein
BBI15_RS13110	COG1511	domain protein
BBI15_RS13115	COG1846	Transcriptional regulator
BBI15_RS13125	COG0626	cystathionine gamma-synthase activity
BBI15_RS13130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BBI15_RS13135	COG1854	S-ribosylhomocysteine lyase activity
BBI15_RS13140	COG2226	methyltransferase
BBI15_RS13150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BBI15_RS13155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBI15_RS13155	COG0551	DNA topoisomerase type I activity
BBI15_RS13160	COG0431	NADPH-dependent FMN reductase
BBI15_RS13175	COG0488	(ABC) transporter
BBI15_RS13185	COG1595	DNA-templated transcription, initiation
BBI15_RS13190	COG4536	flavin adenine dinucleotide binding
BBI15_RS13195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBI15_RS13200	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BBI15_RS13215	COG0584	glycerophosphoryl diester phosphodiesterase
BBI15_RS13235	COG1132	(ABC) transporter
BBI15_RS13240	COG1132	(ABC) transporter
BBI15_RS13245	COG0697	spore germination
BBI15_RS13255	COG3610	response to peptide
BBI15_RS13260	COG2966	Psort location CytoplasmicMembrane, score
BBI15_RS13265	COG1063	alcohol dehydrogenase
BBI15_RS13275	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BBI15_RS13285	COG1960	acyl-CoA dehydrogenase activity
BBI15_RS13295	COG1012	belongs to the aldehyde dehydrogenase family
BBI15_RS13300	COG0789	Transcriptional regulator
BBI15_RS13310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBI15_RS13315	COG0586	Pfam SNARE associated Golgi protein
BBI15_RS13320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BBI15_RS13330	COG4145	pantothenate transmembrane transporter activity
BBI15_RS13345	COG5002	protein histidine kinase activity
BBI15_RS13350	COG0745	RESPONSE REGULATOR receiver
BBI15_RS13355	COG0697	spore germination
BBI15_RS13360	COG0166	Belongs to the GPI family
BBI15_RS13375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBI15_RS13380	COG2011	ABC-type metal ion transport system permease component
BBI15_RS13385	COG1464	Belongs to the NlpA lipoprotein family
BBI15_RS13405	COG0095	Lipoate-protein ligase
BBI15_RS13410	COG1366	Belongs to the anti-sigma-factor antagonist family
BBI15_RS13420	COG3871	stress protein (general stress protein 26)
BBI15_RS13425	COG1959	2 iron, 2 sulfur cluster binding
BBI15_RS13460	COG4895	conserved protein (DUF2196)
BBI15_RS13465	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BBI15_RS13470	COG0753	catalase activity
BBI15_RS13475	COG2066	Belongs to the glutaminase family
BBI15_RS13480	COG0400	carboxylic ester hydrolase activity
BBI15_RS13485	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BBI15_RS13500	COG4667	esterase of the alpha-beta hydrolase superfamily
BBI15_RS13505	COG2135	peptidase activity
BBI15_RS13515	COG2814	Major facilitator Superfamily
BBI15_RS13520	COG0471	metal ion transport
BBI15_RS13530	COG1988	membrane-bound metal-dependent
BBI15_RS13540	COG1253	flavin adenine dinucleotide binding
BBI15_RS13550	COG1295	ribonuclease BN
BBI15_RS13560	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BBI15_RS13565	COG2027	D-alanyl-D-alanine carboxypeptidase
BBI15_RS13570	COG1879	ABC-type sugar transport system periplasmic component
BBI15_RS13575	COG1172	Belongs to the binding-protein-dependent transport system permease family
BBI15_RS13580	COG1129	ABC transporter
BBI15_RS13585	COG1869	D-ribose catabolic process
BBI15_RS13590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBI15_RS13595	COG1609	Transcriptional regulator
BBI15_RS13605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBI15_RS13610	COG1024	Enoyl-CoA hydratase
BBI15_RS13620	COG0183	Belongs to the thiolase family
BBI15_RS13630	COG2031	fatty acid transporter
BBI15_RS13635	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS13655	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBI15_RS13660	COG1024	Enoyl-CoA hydratase
BBI15_RS13665	COG2045	Belongs to the ComB family
BBI15_RS13670	COG1309	transcriptional regulator
BBI15_RS13690	COG1024	Enoyl-CoA hydratase
BBI15_RS13705	COG0318	PFAM AMP-dependent synthetase and ligase
BBI15_RS13710	COG0217	transcriptional regulatory protein
BBI15_RS13715	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BBI15_RS13720	COG1011	Hydrolase
BBI15_RS13725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBI15_RS13730	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BBI15_RS13740	COG0463	Glycosyl transferase, family 2
BBI15_RS13750	COG4485	Bacterial membrane protein, YfhO
BBI15_RS13755	COG2032	superoxide dismutase activity
BBI15_RS13760	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS13770	COG3546	catalase activity
BBI15_RS13780	COG2202	Pas domain
BBI15_RS13780	COG1366	Belongs to the anti-sigma-factor antagonist family
BBI15_RS13795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBI15_RS13805	COG0745	RESPONSE REGULATOR receiver
BBI15_RS13810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BBI15_RS13825	COG1408	metallophosphoesterase
BBI15_RS13830	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BBI15_RS13835	COG1131	(ABC) transporter
BBI15_RS13845	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBI15_RS13850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BBI15_RS13875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBI15_RS13880	COG0730	response to heat
BBI15_RS13895	COG0425	Belongs to the sulfur carrier protein TusA family
BBI15_RS13900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBI15_RS13900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBI15_RS13905	COG0425	Belongs to the sulfur carrier protein TusA family
BBI15_RS13905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBI15_RS13910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBI15_RS13915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBI15_RS13920	COG2210	Belongs to the sulfur carrier protein TusA family
BBI15_RS13925	COG1937	Protein conserved in bacteria
BBI15_RS13930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBI15_RS13930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBI15_RS13965	COG4565	transcriptional regulatory protein
BBI15_RS13970	COG3290	protein histidine kinase activity
BBI15_RS13975	COG1764	response to oxidative stress
BBI15_RS13985	COG1464	Belongs to the NlpA lipoprotein family
BBI15_RS13990	COG2011	ABC-type metal ion transport system permease component
BBI15_RS13995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBI15_RS14000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBI15_RS14005	COG0436	Aminotransferase
BBI15_RS14025	COG3012	SEC-C Motif Domain Protein
BBI15_RS14025	COG1405	negative regulation of cell septum assembly
BBI15_RS14035	COG2323	membrane
BBI15_RS14040	COG1607	acyl-coa hydrolase
BBI15_RS14045	COG2746	aminoglycoside 3-N-acetyltransferase activity
BBI15_RS14065	COG1012	belongs to the aldehyde dehydrogenase family
BBI15_RS14070	COG1187	pseudouridine synthase activity
BBI15_RS14085	COG0517	IMP dehydrogenase activity
BBI15_RS14095	COG1126	abc transporter atp-binding protein
BBI15_RS14100	COG0765	amino acid transport
BBI15_RS14105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBI15_RS14125	COG0463	Glycosyl transferase, family 2
BBI15_RS14130	COG1233	COG1233 Phytoene dehydrogenase and related
BBI15_RS14135	COG1562	ergosterol biosynthetic process
BBI15_RS14150	COG1388	LysM domain
BBI15_RS14150	COG3584	3D domain protein
BBI15_RS14165	COG2308	Evidence 4 Homologs of previously reported genes of
BBI15_RS14185	COG0493	'glutamate synthase
BBI15_RS14190	COG0070	glutamate synthase
BBI15_RS14190	COG0069	glutamate synthase activity
BBI15_RS14190	COG0067	glutamate synthase
BBI15_RS14200	COG0514	ATP-dependent DNA helicase (RecQ)
BBI15_RS14210	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS14220	COG1396	sequence-specific DNA binding
BBI15_RS14245	COG0753	catalase activity
BBI15_RS14250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BBI15_RS14250	COG1215	transferase activity, transferring glycosyl groups
BBI15_RS14255	COG0708	Exodeoxyribonuclease III
BBI15_RS14260	COG2270	Major facilitator Superfamily
BBI15_RS14270	COG3842	ATPase activity
BBI15_RS14275	COG1653	transport
BBI15_RS14280	COG1175	transmembrane transport
BBI15_RS14285	COG0395	ABC-type sugar transport system, permease component
BBI15_RS14290	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BBI15_RS14300	COG0427	acetyl-CoA hydrolase
BBI15_RS14305	COG3279	Response regulator of the LytR AlgR family
BBI15_RS14310	COG0427	acetyl-CoA hydrolase
BBI15_RS14315	COG2814	Major facilitator Superfamily
BBI15_RS14335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BBI15_RS14340	COG2814	Major facilitator Superfamily
BBI15_RS14345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BBI15_RS14360	COG2321	neutral zinc metallopeptidase
BBI15_RS14370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBI15_RS14375	COG1366	Belongs to the anti-sigma-factor antagonist family
BBI15_RS14380	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBI15_RS14380	COG2247	cell wall binding repeat
BBI15_RS14395	COG0300	oxidoreductase activity
BBI15_RS14400	COG4221	oxidoreductase activity
BBI15_RS14410	COG1595	DNA-templated transcription, initiation
BBI15_RS14440	COG5001	Diguanylate cyclase
BBI15_RS14440	COG3300	MHYT domain
BBI15_RS14465	COG3279	Response regulator of the LytR AlgR family
BBI15_RS14480	COG0488	(ABC) transporter
BBI15_RS14490	COG0667	Aldo Keto reductase
BBI15_RS14525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBI15_RS14545	COG1061	Type III restriction enzyme res subunit
BBI15_RS14575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBI15_RS14580	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BBI15_RS14585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BBI15_RS14610	COG0739	heme binding
BBI15_RS14610	COG0741	lytic transglycosylase activity
BBI15_RS14610	COG1196	nuclear chromosome segregation
BBI15_RS14615	COG0366	Alpha amylase catalytic
BBI15_RS14635	COG2226	methyltransferase
BBI15_RS14655	COG0385	Bile acid
BBI15_RS14785	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS14820	COG2202	Pas domain
BBI15_RS14820	COG1366	Belongs to the anti-sigma-factor antagonist family
BBI15_RS14825	COG0789	Transcriptional regulator
BBI15_RS14835	COG0519	Catalyzes the synthesis of GMP from XMP
BBI15_RS14845	COG1404	Belongs to the peptidase S8 family
BBI15_RS14855	COG2234	aminopeptidase activity
BBI15_RS14860	COG2234	aminopeptidase activity
BBI15_RS14890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBI15_RS14895	COG1289	transmembrane transporter activity
BBI15_RS14905	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BBI15_RS14920	COG1959	2 iron, 2 sulfur cluster binding
BBI15_RS14935	COG0471	metal ion transport
BBI15_RS14940	COG2828	Protein conserved in bacteria
BBI15_RS14955	COG1794	racemase activity, acting on amino acids and derivatives
BBI15_RS14975	COG0656	L-ascorbic acid biosynthetic process
BBI15_RS14980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBI15_RS14985	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BBI15_RS14990	COG0569	domain protein
BBI15_RS15000	COG0668	transmembrane transport
BBI15_RS15005	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS15025	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BBI15_RS15045	COG1215	transferase activity, transferring glycosyl groups
BBI15_RS15050	COG0745	RESPONSE REGULATOR receiver
BBI15_RS15055	COG5002	protein histidine kinase activity
BBI15_RS15060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBI15_RS15065	COG1366	Belongs to the anti-sigma-factor antagonist family
BBI15_RS15080	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS15100	COG1757	Na H antiporter
BBI15_RS15145	COG2132	Multicopper oxidase
BBI15_RS15165	COG0367	asparagine synthase
BBI15_RS15170	COG5002	protein histidine kinase activity
BBI15_RS15175	COG0745	RESPONSE REGULATOR receiver
BBI15_RS15190	COG2608	mercury ion transmembrane transporter activity
BBI15_RS15195	COG0745	RESPONSE REGULATOR receiver
BBI15_RS15200	COG5002	protein histidine kinase activity
BBI15_RS15210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBI15_RS15215	COG0785	Cytochrome C biogenesis protein
BBI15_RS15220	COG1388	LysM domain
BBI15_RS15225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBI15_RS15230	COG1686	Belongs to the peptidase S11 family
BBI15_RS15260	COG0534	Mate efflux family protein
BBI15_RS15300	COG2226	methyltransferase
BBI15_RS15320	COG2409	Drug exporters of the RND superfamily
BBI15_RS15335	COG0604	alcohol dehydrogenase
BBI15_RS15345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBI15_RS15345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBI15_RS15360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BBI15_RS15365	COG1012	belongs to the aldehyde dehydrogenase family
BBI15_RS15370	COG3340	Belongs to the peptidase S51 family
BBI15_RS15400	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BBI15_RS15405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BBI15_RS15415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBI15_RS15425	COG0179	Fumarylacetoacetate (FAA) hydrolase
BBI15_RS15450	COG3181	Tripartite tricarboxylate transporter family receptor
BBI15_RS15455	COG2059	Chromate
BBI15_RS15460	COG2059	Chromate
BBI15_RS15475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBI15_RS15480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BBI15_RS15500	COG0066	3-isopropylmalate dehydratase activity
BBI15_RS15505	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BBI15_RS15510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBI15_RS15515	COG1802	Transcriptional regulator
BBI15_RS15520	COG2223	nitrite transmembrane transporter activity
BBI15_RS15525	COG0154	amidase activity
BBI15_RS15550	COG0716	FMN binding
BBI15_RS15555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBI15_RS15560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBI15_RS15575	COG0386	Belongs to the glutathione peroxidase family
BBI15_RS15580	COG1846	Transcriptional regulator
BBI15_RS15585	COG1764	response to oxidative stress
BBI15_RS15595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BBI15_RS15600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BBI15_RS15610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBI15_RS15615	COG0589	response to stress
BBI15_RS15625	COG0739	heme binding
BBI15_RS15645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBI15_RS15665	COG1301	dicarboxylic acid transport
BBI15_RS15670	COG2329	Antibiotic biosynthesis monooxygenase
BBI15_RS15680	COG2814	Major facilitator Superfamily
BBI15_RS15685	COG0662	Cupin 2, conserved barrel domain protein
BBI15_RS15690	COG0492	ferredoxin-NADP+ reductase activity
BBI15_RS15695	COG1120	ATPase activity
BBI15_RS15700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBI15_RS15705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBI15_RS15710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBI15_RS15715	COG1757	Na H antiporter
BBI15_RS15725	COG2239	Acts as a magnesium transporter
BBI15_RS15760	COG1785	Belongs to the alkaline phosphatase family
BBI15_RS15765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BBI15_RS15770	COG1309	transcriptional regulator
BBI15_RS15775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBI15_RS15785	COG1496	oxidoreductase activity
BBI15_RS15790	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBI15_RS15800	COG1028	Short-chain dehydrogenase reductase Sdr
BBI15_RS15815	COG0579	oxidoreductase
BBI15_RS15820	COG0519	Catalyzes the synthesis of GMP from XMP
BBI15_RS15845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBI15_RS15865	COG0747	negative chemotaxis
BBI15_RS15870	COG4894	glucomannan catabolic process
BBI15_RS15890	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BBI15_RS15905	COG4608	Belongs to the ABC transporter superfamily
BBI15_RS15910	COG0444	Belongs to the ABC transporter superfamily
BBI15_RS15915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBI15_RS15925	COG0747	negative chemotaxis
BBI15_RS15935	COG2040	homocysteine
BBI15_RS15940	COG1126	abc transporter atp-binding protein
BBI15_RS15945	COG0765	amino acid transport
BBI15_RS15950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBI15_RS15960	COG0450	alkyl hydroperoxide reductase
BBI15_RS15985	COG3493	citrate carrier protein
BBI15_RS15990	COG4565	transcriptional regulatory protein
BBI15_RS15995	COG3290	protein histidine kinase activity
BBI15_RS16045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBI15_RS16055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BBI15_RS16060	COG4853	Protein conserved in bacteria
BBI15_RS16070	COG5002	protein histidine kinase activity
BBI15_RS16075	COG0745	RESPONSE REGULATOR receiver
BBI15_RS16085	COG0739	heme binding
BBI15_RS16085	COG0741	lytic transglycosylase activity
BBI15_RS16085	COG1196	nuclear chromosome segregation
BBI15_RS16090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BBI15_RS16095	COG0305	Participates in initiation and elongation during chromosome replication
BBI15_RS16100	COG0359	binds to the 23S rRNA
BBI15_RS16105	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BBI15_RS16120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BBI15_RS16130	COG0360	Binds together with S18 to 16S ribosomal RNA
BBI15_RS16145	COG0012	GTP binding
BBI15_RS16150	COG4481	Protein conserved in bacteria
BBI15_RS16155	COG0668	transmembrane transport
BBI15_RS16160	COG1811	Na channel or pump
BBI15_RS16165	COG1475	DNA binding
BBI15_RS16170	COG1192	Involved in chromosome partitioning
BBI15_RS16195	COG1847	R3H domain protein
BBI15_RS16205	COG0594	ribonuclease P activity