locus-tag	class	description
FGL15_RS00045	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FGL15_RS00055	COG2197	response regulator
FGL15_RS00080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FGL15_RS00115	COG0297	glycogen (starch) synthase activity
FGL15_RS00120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FGL15_RS00130	COG1064	alcohol dehydrogenase
FGL15_RS00155	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGL15_RS00155	COG0596	Alpha beta hydrolase
FGL15_RS00175	COG2205	protein histidine kinase activity
FGL15_RS00180	COG0745	RESPONSE REGULATOR receiver
FGL15_RS00190	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FGL15_RS00205	COG2205	protein histidine kinase activity
FGL15_RS00210	COG1473	amidohydrolase
FGL15_RS00215	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FGL15_RS00220	COG0402	S-adenosylhomocysteine deaminase activity
FGL15_RS00255	COG0444	Belongs to the ABC transporter superfamily
FGL15_RS00260	COG4166	transmembrane transport
FGL15_RS00270	COG0601	transmembrane transport
FGL15_RS00285	COG1024	Enoyl-CoA hydratase
FGL15_RS00295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FGL15_RS00300	COG1695	Transcriptional regulator
FGL15_RS00305	COG4221	oxidoreductase activity
FGL15_RS00310	COG0386	Belongs to the glutathione peroxidase family
FGL15_RS00335	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS00350	COG1309	transcriptional regulator
FGL15_RS00365	COG1733	regulation of RNA biosynthetic process
FGL15_RS00410	COG0318	PFAM AMP-dependent synthetase and ligase
FGL15_RS00435	COG1160	GTP binding
FGL15_RS00440	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FGL15_RS00455	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FGL15_RS00460	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FGL15_RS00475	COG0494	nUDIX hydrolase
FGL15_RS00480	COG0504	CTP synthase activity
FGL15_RS00485	COG0497	DNA recombination
FGL15_RS00490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FGL15_RS00500	COG0647	UMP catabolic process
FGL15_RS00530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGL15_RS00545	COG2094	Belongs to the DNA glycosylase MPG family
FGL15_RS00550	COG0165	Argininosuccinate lyase
FGL15_RS00555	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FGL15_RS00560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGL15_RS00565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FGL15_RS00575	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FGL15_RS00580	COG2197	response regulator
FGL15_RS00595	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGL15_RS00600	COG0072	phenylalanine-tRNA ligase activity
FGL15_RS00600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL15_RS00605	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FGL15_RS00610	COG0765	amino acid transport
FGL15_RS00615	COG0765	amino acid transport
FGL15_RS00620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL15_RS00625	COG1126	abc transporter atp-binding protein
FGL15_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGL15_RS00635	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FGL15_RS00640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FGL15_RS00645	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FGL15_RS00665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FGL15_RS00670	COG0131	Imidazoleglycerol-phosphate dehydratase
FGL15_RS00685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGL15_RS00690	COG0531	amino acid
FGL15_RS00695	COG1388	LysM domain
FGL15_RS00700	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FGL15_RS00705	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGL15_RS00720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FGL15_RS00725	COG2813	Specifically methylates the guanine in position
FGL15_RS00730	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FGL15_RS00735	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FGL15_RS00740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGL15_RS00750	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FGL15_RS00760	COG1396	sequence-specific DNA binding
FGL15_RS00765	COG1546	Belongs to the CinA family
FGL15_RS00765	COG1058	Belongs to the CinA family
FGL15_RS00775	COG1674	ftsk spoiiie
FGL15_RS00785	COG0577	efflux transmembrane transporter activity
FGL15_RS00785	COG1136	(ABC) transporter
FGL15_RS00790	COG0577	efflux transmembrane transporter activity
FGL15_RS00790	COG1136	(ABC) transporter
FGL15_RS00800	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FGL15_RS00805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGL15_RS00825	COG1090	epimerase
FGL15_RS00845	COG0612	Peptidase, M16
FGL15_RS00865	COG1960	acyl-CoA dehydrogenase activity
FGL15_RS00875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FGL15_RS00880	COG1309	transcriptional regulator
FGL15_RS00890	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGL15_RS00895	COG0022	dehydrogenase e1 component
FGL15_RS00905	COG1185	polyribonucleotide nucleotidyltransferase activity
FGL15_RS00915	COG3594	Acyltransferase
FGL15_RS00930	COG0531	amino acid
FGL15_RS00935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FGL15_RS00965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGL15_RS00985	COG2814	Major facilitator Superfamily
FGL15_RS00990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGL15_RS00995	COG0545	Peptidyl-prolyl cis-trans isomerase
FGL15_RS01000	COG0179	Fumarylacetoacetate (FAA) hydrolase
FGL15_RS01015	COG2252	PERMEase
FGL15_RS01020	COG2233	PERMEase
FGL15_RS01070	COG1012	belongs to the aldehyde dehydrogenase family
FGL15_RS01090	COG0039	L-malate dehydrogenase activity
FGL15_RS01095	COG0702	epimerase
FGL15_RS01105	COG1012	belongs to the aldehyde dehydrogenase family
FGL15_RS01110	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FGL15_RS01115	COG2390	Transcriptional regulator
FGL15_RS01120	COG2807	transmembrane transport
FGL15_RS01125	COG0196	riboflavin kinase activity
FGL15_RS01140	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FGL15_RS01155	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FGL15_RS01160	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FGL15_RS01180	COG0745	RESPONSE REGULATOR receiver
FGL15_RS01190	COG0442	prolyl-tRNA aminoacylation
FGL15_RS01220	COG0714	Associated with various cellular activities
FGL15_RS01225	COG1083	cytidylyl-transferase
FGL15_RS01230	COG2089	acid synthase
FGL15_RS01245	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FGL15_RS01255	COG2197	response regulator
FGL15_RS01260	COG3851	Histidine kinase
FGL15_RS01265	COG0750	zinc metalloprotease
FGL15_RS01270	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FGL15_RS01280	COG0318	PFAM AMP-dependent synthetase and ligase
FGL15_RS01280	COG0204	Acyl-transferase
FGL15_RS01305	COG0631	protein serine/threonine phosphatase activity
FGL15_RS01315	COG5002	protein histidine kinase activity
FGL15_RS01360	COG0667	Aldo Keto reductase
FGL15_RS01365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGL15_RS01370	COG2818	Glycosylase
FGL15_RS01380	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FGL15_RS01385	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FGL15_RS01390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FGL15_RS01395	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FGL15_RS01400	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGL15_RS01405	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGL15_RS01410	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGL15_RS01415	COG0356	it plays a direct role in the translocation of protons across the membrane
FGL15_RS01425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGL15_RS01435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGL15_RS01460	COG2890	protein-(glutamine-N5) methyltransferase activity
FGL15_RS01470	COG1045	serine acetyltransferase
FGL15_RS01475	COG0488	(ABC) transporter
FGL15_RS01480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FGL15_RS01490	COG0083	homoserine kinase activity
FGL15_RS01495	COG0460	homoserine dehydrogenase
FGL15_RS01510	COG0018	arginyl-trna synthetase
FGL15_RS01515	COG1305	Transglutaminase-like
FGL15_RS01525	COG0736	holo-[acyl-carrier-protein] synthase activity
FGL15_RS01540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FGL15_RS01550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FGL15_RS01560	COG1842	Phage shock protein A
FGL15_RS01570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGL15_RS01595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL15_RS01625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL15_RS01630	COG0601	transmembrane transport
FGL15_RS01645	COG0154	amidase activity
FGL15_RS01655	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FGL15_RS01660	COG3340	Belongs to the peptidase S51 family
FGL15_RS01670	COG2814	Major facilitator Superfamily
FGL15_RS01685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FGL15_RS01700	COG2197	response regulator
FGL15_RS01705	COG2814	Major facilitator Superfamily
FGL15_RS01720	COG0633	Ferredoxin
FGL15_RS01720	COG0543	2 iron, 2 sulfur cluster binding
FGL15_RS01740	COG1902	pentaerythritol trinitrate reductase activity
FGL15_RS01775	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGL15_RS01775	COG0567	Dehydrogenase, E1 component
FGL15_RS01780	COG0025	NhaP-type Na H and K H
FGL15_RS01790	COG1595	DNA-templated transcription, initiation
FGL15_RS01795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FGL15_RS01855	COG0653	protein targeting
FGL15_RS01870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FGL15_RS01875	COG5401	PFAM Sporulation and spore germination
FGL15_RS01885	COG5000	phosphorelay sensor kinase activity
FGL15_RS01885	COG5002	protein histidine kinase activity
FGL15_RS01890	COG0745	RESPONSE REGULATOR receiver
FGL15_RS01910	COG0714	Associated with various cellular activities
FGL15_RS01940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FGL15_RS01970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FGL15_RS01980	COG1482	cell wall glycoprotein biosynthetic process
FGL15_RS01985	COG1960	acyl-CoA dehydrogenase activity
FGL15_RS02025	COG1216	Glycosyl transferase, family 2
FGL15_RS02050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGL15_RS02060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGL15_RS02065	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FGL15_RS02105	COG0438	transferase activity, transferring glycosyl groups
FGL15_RS02105	COG1216	Glycosyl transferase, family 2
FGL15_RS02130	COG0463	Glycosyl transferase, family 2
FGL15_RS02135	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FGL15_RS02155	COG0438	transferase activity, transferring glycosyl groups
FGL15_RS02155	COG1216	Glycosyl transferase, family 2
FGL15_RS02185	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FGL15_RS02195	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FGL15_RS02195	COG2755	lipolytic protein G-D-S-L family
FGL15_RS02200	COG3425	synthase
FGL15_RS02225	COG0069	glutamate synthase activity
FGL15_RS02225	COG0067	glutamate synthase
FGL15_RS02225	COG0070	glutamate synthase
FGL15_RS02230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FGL15_RS02255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FGL15_RS02290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGL15_RS02300	COG4770	biotin carboxylase activity
FGL15_RS02305	COG4566	intracellular signal transduction
FGL15_RS02320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGL15_RS02335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FGL15_RS02355	COG1079	Belongs to the binding-protein-dependent transport system permease family
FGL15_RS02360	COG4603	Belongs to the binding-protein-dependent transport system permease family
FGL15_RS02365	COG3845	ABC transporter
FGL15_RS02385	COG0488	(ABC) transporter
FGL15_RS02405	COG0598	Magnesium transport protein CorA
FGL15_RS02410	COG2009	succinate dehydrogenase
FGL15_RS02425	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FGL15_RS02430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGL15_RS02440	COG0708	Exodeoxyribonuclease III
FGL15_RS02445	COG0180	Tryptophanyl-tRNA synthetase
FGL15_RS02455	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FGL15_RS02460	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGL15_RS02485	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGL15_RS02485	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGL15_RS02495	COG0477	Major facilitator Superfamily
FGL15_RS02500	COG1132	(ABC) transporter
FGL15_RS02510	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FGL15_RS02530	COG2267	carboxylic ester hydrolase activity
FGL15_RS02535	COG2409	Drug exporters of the RND superfamily
FGL15_RS02540	COG1335	isochorismatase
FGL15_RS02570	COG1609	Transcriptional regulator
FGL15_RS02590	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS02605	COG1070	Carbohydrate kinase
FGL15_RS02610	COG1105	Belongs to the carbohydrate kinase PfkB family
FGL15_RS02650	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGL15_RS02665	COG1609	Transcriptional regulator
FGL15_RS02695	COG1072	(Pantothenic acid kinase))
FGL15_RS02700	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS02705	COG1609	Transcriptional regulator
FGL15_RS02720	COG2827	Endonuclease containing a URI domain
FGL15_RS02755	COG0789	Transcriptional regulator
FGL15_RS02765	COG2375	cellular response to nickel ion
FGL15_RS02765	COG1132	(ABC) transporter
FGL15_RS02775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS02780	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS02785	COG3655	Transcriptional regulator
FGL15_RS02810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGL15_RS02815	COG0697	spore germination
FGL15_RS02820	COG2808	Putative FMN-binding domain
FGL15_RS02840	COG2040	homocysteine
FGL15_RS02845	COG0477	Major facilitator Superfamily
FGL15_RS02855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGL15_RS02880	COG1175	transmembrane transport
FGL15_RS02885	COG0395	ABC-type sugar transport system, permease component
FGL15_RS02895	COG1621	beta-fructofuranosidase activity
FGL15_RS02900	COG1621	beta-fructofuranosidase activity
FGL15_RS02915	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FGL15_RS02920	COG3152	Membrane
FGL15_RS02970	COG1609	Transcriptional regulator
FGL15_RS02980	COG1175	transmembrane transport
FGL15_RS02990	COG1621	beta-fructofuranosidase activity
FGL15_RS02995	COG2267	carboxylic ester hydrolase activity
FGL15_RS03000	COG2909	trisaccharide binding
FGL15_RS03030	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FGL15_RS03035	COG3639	organic phosphonate transmembrane transporter activity
FGL15_RS03040	COG3639	organic phosphonate transmembrane transporter activity
FGL15_RS03050	COG0747	negative chemotaxis
FGL15_RS03055	COG1335	isochorismatase
FGL15_RS03070	COG0789	Transcriptional regulator
FGL15_RS03090	COG5002	protein histidine kinase activity
FGL15_RS03095	COG0667	Aldo Keto reductase
FGL15_RS03250	COG1192	Involved in chromosome partitioning
FGL15_RS03270	COG0587	DNA-directed DNA polymerase activity
FGL15_RS03290	COG0003	Pfam Anion-transporting ATPase
FGL15_RS03305	COG0395	ABC-type sugar transport system, permease component
FGL15_RS03330	COG4221	oxidoreductase activity
FGL15_RS03340	COG4221	oxidoreductase activity
FGL15_RS03365	COG0395	ABC-type sugar transport system, permease component
FGL15_RS03370	COG1175	transmembrane transport
FGL15_RS03385	COG1609	Transcriptional regulator
FGL15_RS03450	COG0587	DNA-directed DNA polymerase activity
FGL15_RS03470	COG4585	Histidine kinase
FGL15_RS03475	COG2197	response regulator
FGL15_RS03480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGL15_RS03530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS03535	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS03545	COG1175	transmembrane transport
FGL15_RS03550	COG0395	ABC-type sugar transport system, permease component
FGL15_RS03575	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS03580	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FGL15_RS03600	COG4585	Histidine kinase
FGL15_RS03605	COG2197	response regulator
FGL15_RS03655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS03660	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS03675	COG3711	transcriptional antiterminator
FGL15_RS03705	COG0582	viral genome integration into host DNA
FGL15_RS03725	COG0470	DNA polymerase III
FGL15_RS03730	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FGL15_RS03735	COG1754	DNA topoisomerase type I activity
FGL15_RS03735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FGL15_RS03785	COG1957	nucleoside hydrolase
FGL15_RS03790	COG0477	Major facilitator Superfamily
FGL15_RS03795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGL15_RS03810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGL15_RS03815	COG2852	Protein conserved in bacteria
FGL15_RS03825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGL15_RS03830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGL15_RS03865	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FGL15_RS03870	COG1435	thymidine kinase activity
FGL15_RS03875	COG0579	oxidoreductase
FGL15_RS03900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FGL15_RS03925	COG0395	ABC-type sugar transport system, permease component
FGL15_RS03930	COG1175	transmembrane transport
FGL15_RS03950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGL15_RS03950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGL15_RS03950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGL15_RS03960	COG1349	DNA-binding transcription factor activity
FGL15_RS04010	COG1175	transmembrane transport
FGL15_RS04015	COG0395	ABC-type sugar transport system, permease component
FGL15_RS04065	COG0489	protein tyrosine kinase activity
FGL15_RS04070	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGL15_RS04090	COG0438	transferase activity, transferring glycosyl groups
FGL15_RS04125	COG2755	lipolytic protein G-D-S-L family
FGL15_RS04125	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FGL15_RS04150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGL15_RS04175	COG0702	epimerase
FGL15_RS04185	COG0714	Associated with various cellular activities
FGL15_RS04195	COG1305	Transglutaminase-like
FGL15_RS04210	COG0534	Mate efflux family protein
FGL15_RS04215	COG0454	-acetyltransferase
FGL15_RS04225	COG1349	DNA-binding transcription factor activity
FGL15_RS04270	COG0433	COG0433 Predicted ATPase
FGL15_RS04275	COG3046	protein related to deoxyribodipyrimidine photolyase
FGL15_RS04280	COG0673	inositol 2-dehydrogenase activity
FGL15_RS04295	COG3226	Transcriptional regulator
FGL15_RS04300	COG3534	alpha-L-arabinofuranosidase
FGL15_RS04310	COG1175	transmembrane transport
FGL15_RS04335	COG3012	SEC-C Motif Domain Protein
FGL15_RS04340	COG2814	Major facilitator Superfamily
FGL15_RS04345	COG0326	Molecular chaperone. Has ATPase activity
FGL15_RS04370	COG0395	ABC-type sugar transport system, permease component
FGL15_RS04410	COG4214	carbohydrate transport
FGL15_RS04415	COG1129	ABC transporter
FGL15_RS04420	COG4213	ABC transporter substrate-binding protein
FGL15_RS04425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FGL15_RS04430	COG1609	Transcriptional regulator
FGL15_RS04435	COG1846	Transcriptional regulator
FGL15_RS04435	COG1940	carbohydrate kinase activity
FGL15_RS04455	COG0673	inositol 2-dehydrogenase activity
FGL15_RS04470	COG1175	transmembrane transport
FGL15_RS04480	COG0673	inositol 2-dehydrogenase activity
FGL15_RS04490	COG2115	Belongs to the xylose isomerase family
FGL15_RS04495	COG1070	Carbohydrate kinase
FGL15_RS04505	COG1929	Belongs to the glycerate kinase type-1 family
FGL15_RS04510	COG0006	proline dipeptidase activity
FGL15_RS04520	COG1609	Transcriptional regulator
FGL15_RS04530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGL15_RS04535	COG4948	Mandelate Racemase Muconate Lactonizing
FGL15_RS04550	COG0673	inositol 2-dehydrogenase activity
FGL15_RS04565	COG0395	ABC-type sugar transport system, permease component
FGL15_RS04570	COG1175	transmembrane transport
FGL15_RS04575	COG0673	inositol 2-dehydrogenase activity
FGL15_RS04620	COG1321	iron dependent repressor
FGL15_RS04660	COG0668	transmembrane transport
FGL15_RS04670	COG1132	(ABC) transporter
FGL15_RS04680	COG0395	ABC-type sugar transport system, permease component
FGL15_RS04685	COG1175	transmembrane transport
FGL15_RS04690	COG1653	transport
FGL15_RS04695	COG1609	Transcriptional regulator
FGL15_RS04700	COG2814	Major facilitator Superfamily
FGL15_RS04710	COG0222	ribosome binding
FGL15_RS04715	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FGL15_RS04730	COG0135	phosphoribosylanthranilate isomerase activity
FGL15_RS04735	COG2205	protein histidine kinase activity
FGL15_RS04740	COG0745	RESPONSE REGULATOR receiver
FGL15_RS04750	COG1136	(ABC) transporter
FGL15_RS04750	COG0577	efflux transmembrane transporter activity
FGL15_RS04755	COG0477	Major facilitator Superfamily
FGL15_RS04765	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FGL15_RS04780	COG0673	inositol 2-dehydrogenase activity
FGL15_RS04810	COG3321	synthase
FGL15_RS04810	COG0604	alcohol dehydrogenase
FGL15_RS04820	COG0081	regulation of translation
FGL15_RS04830	COG0250	Participates in transcription elongation, termination and antitermination
FGL15_RS04855	COG1902	pentaerythritol trinitrate reductase activity
FGL15_RS04870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FGL15_RS04875	COG0436	Aminotransferase
FGL15_RS04880	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FGL15_RS04890	COG2030	dehydratase
FGL15_RS04895	COG0730	response to heat
FGL15_RS04900	COG0406	alpha-ribazole phosphatase activity
FGL15_RS05030	COG0028	Belongs to the TPP enzyme family
FGL15_RS05035	COG1088	dTDP-glucose 4,6-dehydratase activity
FGL15_RS05040	COG0739	heme binding
FGL15_RS05065	COG1666	GTP binding
FGL15_RS05085	COG0142	geranyltranstransferase activity
FGL15_RS05095	COG0531	amino acid
FGL15_RS05100	COG2226	methyltransferase
FGL15_RS05115	COG1169	isochorismate synthase
FGL15_RS05120	COG2326	polyphosphate kinase activity
FGL15_RS05125	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FGL15_RS05140	COG1575	Belongs to the MenA family. Type 1 subfamily
FGL15_RS05165	COG4948	Mandelate Racemase Muconate Lactonizing
FGL15_RS05170	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FGL15_RS05180	COG0785	Cytochrome C biogenesis protein
FGL15_RS05190	COG0406	alpha-ribazole phosphatase activity
FGL15_RS05195	COG0017	Asparaginyl-tRNA synthetase
FGL15_RS05205	COG2890	protein-(glutamine-N5) methyltransferase activity
FGL15_RS05220	COG1396	sequence-specific DNA binding
FGL15_RS05240	COG0640	Transcriptional regulator
FGL15_RS05245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FGL15_RS05250	COG0569	domain protein
FGL15_RS05270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FGL15_RS05290	COG0745	RESPONSE REGULATOR receiver
FGL15_RS05305	COG1595	DNA-templated transcription, initiation
FGL15_RS05325	COG4974	Belongs to the 'phage' integrase family
FGL15_RS05645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGL15_RS05645	COG2169	Transcriptional regulator
FGL15_RS05650	COG0415	Belongs to the DNA photolyase family
FGL15_RS05655	COG2197	response regulator
FGL15_RS05670	COG1136	(ABC) transporter
FGL15_RS05685	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FGL15_RS05685	COG0352	thiamine-phosphate diphosphorylase activity
FGL15_RS05685	COG0351	phosphomethylpyrimidine kinase
FGL15_RS05695	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FGL15_RS05710	COG0586	Pfam SNARE associated Golgi protein
FGL15_RS05725	COG0697	spore germination
FGL15_RS05730	COG2188	Transcriptional regulator
FGL15_RS05735	COG2205	protein histidine kinase activity
FGL15_RS05740	COG0745	RESPONSE REGULATOR receiver
FGL15_RS05750	COG2376	Dihydroxyacetone kinase
FGL15_RS05755	COG0698	ribose 5-phosphate isomerase
FGL15_RS05760	COG0149	triose-phosphate isomerase activity
FGL15_RS05770	COG2271	Major facilitator Superfamily
FGL15_RS05775	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS05780	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGL15_RS05805	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGL15_RS05815	COG1609	Transcriptional regulator
FGL15_RS05825	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGL15_RS05835	COG1129	ABC transporter
FGL15_RS05840	COG1879	ABC-type sugar transport system periplasmic component
FGL15_RS05845	COG2188	Transcriptional regulator
FGL15_RS05860	COG2205	protein histidine kinase activity
FGL15_RS05865	COG0745	RESPONSE REGULATOR receiver
FGL15_RS05875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGL15_RS05885	COG0515	serine threonine protein kinase
FGL15_RS05885	COG2815	serine threonine protein kinase
FGL15_RS05905	COG0477	Major facilitator Superfamily
FGL15_RS05935	COG0395	ABC-type sugar transport system, permease component
FGL15_RS05940	COG1175	transmembrane transport
FGL15_RS05965	COG1609	Transcriptional regulator
FGL15_RS05970	COG0667	Aldo Keto reductase
FGL15_RS05990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGL15_RS06000	COG1486	melibiose metabolic process
FGL15_RS06010	COG1175	transmembrane transport
FGL15_RS06020	COG2222	sugar isomerase
FGL15_RS06035	COG0789	Transcriptional regulator
FGL15_RS06055	COG4552	Acetyltransferase involved in intracellular survival and related
FGL15_RS06070	COG0789	Transcriptional regulator
FGL15_RS06080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGL15_RS06085	COG0156	8-amino-7-oxononanoate synthase activity
FGL15_RS06090	COG1063	alcohol dehydrogenase
FGL15_RS06095	COG0346	lactoylglutathione lyase activity
FGL15_RS06210	COG4335	DNA alkylation repair
FGL15_RS06275	COG4552	Acetyltransferase involved in intracellular survival and related
FGL15_RS06285	COG1522	sequence-specific DNA binding
FGL15_RS06290	COG1012	belongs to the aldehyde dehydrogenase family
FGL15_RS06300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGL15_RS06305	COG1012	belongs to the aldehyde dehydrogenase family
FGL15_RS06315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FGL15_RS06370	COG1063	alcohol dehydrogenase
FGL15_RS06475	COG1733	regulation of RNA biosynthetic process
FGL15_RS06485	COG2311	Membrane
FGL15_RS06495	COG1846	Transcriptional regulator
FGL15_RS06515	COG1464	Belongs to the NlpA lipoprotein family
FGL15_RS06525	COG2011	ABC-type metal ion transport system permease component
FGL15_RS06555	COG1175	transmembrane transport
FGL15_RS06570	COG1349	DNA-binding transcription factor activity
FGL15_RS06630	COG0328	RNA-DNA hybrid ribonuclease activity
FGL15_RS06660	COG1316	TRANSCRIPTIONal
FGL15_RS06675	COG0561	phosphatase activity
FGL15_RS06680	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FGL15_RS06685	COG1597	lipid kinase activity
FGL15_RS06690	COG2986	histidine ammonia-lyase
FGL15_RS06710	COG1174	glycine betaine transport
FGL15_RS06720	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FGL15_RS06730	COG1228	amidohydrolase
FGL15_RS06735	COG1228	amidohydrolase
FGL15_RS06745	COG0747	negative chemotaxis
FGL15_RS06750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGL15_RS06760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FGL15_RS06775	COG0077	Prephenate dehydratase
FGL15_RS06805	COG1876	peptidase activity
FGL15_RS06815	COG0477	Major facilitator Superfamily
FGL15_RS06830	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FGL15_RS06840	COG2326	polyphosphate kinase activity
FGL15_RS06855	COG0095	Lipoate-protein ligase
FGL15_RS06860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGL15_RS06870	COG0598	Magnesium transport protein CorA
FGL15_RS06875	COG1846	Transcriptional regulator
FGL15_RS06880	COG2814	Major facilitator Superfamily
FGL15_RS06905	COG1305	Transglutaminase-like
FGL15_RS06920	COG0667	Aldo Keto reductase
FGL15_RS06935	COG3386	PFAM SMP-30 Gluconolaconase
FGL15_RS06940	COG1609	Transcriptional regulator
FGL15_RS06950	COG0300	oxidoreductase activity
FGL15_RS06955	COG1653	transport
FGL15_RS06965	COG3833	ABC-type maltose transport systems, permease component
FGL15_RS07000	COG2378	regulation of single-species biofilm formation
FGL15_RS07035	COG5564	TIM-barrel signal transduction protein
FGL15_RS07050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGL15_RS07080	COG1487	ribonuclease activity
FGL15_RS07085	COG1609	Transcriptional regulator
FGL15_RS07090	COG2205	protein histidine kinase activity
FGL15_RS07095	COG0745	RESPONSE REGULATOR receiver
FGL15_RS07100	COG1129	ABC transporter
FGL15_RS07105	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGL15_RS07125	COG4989	oxidoreductase activity
FGL15_RS07145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGL15_RS07165	COG2267	carboxylic ester hydrolase activity
FGL15_RS07175	COG1349	DNA-binding transcription factor activity
FGL15_RS07180	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS07180	COG3347	Dehydrogenase
FGL15_RS07185	COG1070	Carbohydrate kinase
FGL15_RS07190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGL15_RS07195	COG2186	Transcriptional regulator
FGL15_RS07205	COG2910	NAD(P)H-binding
FGL15_RS07210	COG1216	Glycosyl transferase, family 2
FGL15_RS07220	COG1834	amidinotransferase
FGL15_RS07230	COG1725	Transcriptional regulator
FGL15_RS07235	COG1012	belongs to the aldehyde dehydrogenase family
FGL15_RS07275	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FGL15_RS07280	COG2079	MmgE PrpD family protein
FGL15_RS07290	COG1396	sequence-specific DNA binding
FGL15_RS07300	COG1024	Enoyl-CoA hydratase
FGL15_RS07310	COG0183	Belongs to the thiolase family
FGL15_RS07315	COG1054	Belongs to the UPF0176 family
FGL15_RS07325	COG0039	L-malate dehydrogenase activity
FGL15_RS07340	COG0604	alcohol dehydrogenase
FGL15_RS07360	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FGL15_RS07375	COG0181	hydroxymethylbilane synthase activity
FGL15_RS07380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FGL15_RS07385	COG3253	May function as heme-dependent peroxidase
FGL15_RS07410	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FGL15_RS07415	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FGL15_RS07420	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FGL15_RS07440	COG0494	nUDIX hydrolase
FGL15_RS07475	COG0395	ABC-type sugar transport system, permease component
FGL15_RS07490	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FGL15_RS07495	COG1737	Transcriptional regulator
FGL15_RS07535	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FGL15_RS07565	COG1609	Transcriptional regulator
FGL15_RS07575	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FGL15_RS07585	COG0583	DNA-binding transcription factor activity
FGL15_RS07600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS07605	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FGL15_RS07635	COG2072	flavoprotein involved in K transport
FGL15_RS07640	COG0697	spore germination
FGL15_RS07680	COG0596	Alpha beta hydrolase
FGL15_RS07695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FGL15_RS07710	COG0419	ATPase involved in DNA repair
FGL15_RS07715	COG0419	ATPase involved in DNA repair
FGL15_RS07720	COG0420	3'-5' exonuclease activity
FGL15_RS07725	COG0776	regulation of translation
FGL15_RS07730	COG0477	Major facilitator Superfamily
FGL15_RS07735	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FGL15_RS07740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FGL15_RS07745	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FGL15_RS07775	COG0701	Predicted permease
FGL15_RS07780	COG0735	belongs to the Fur family
FGL15_RS07790	COG3842	ATPase activity
FGL15_RS07795	COG0803	Belongs to the bacterial solute-binding protein 9 family
FGL15_RS07810	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGL15_RS07815	COG0022	dehydrogenase e1 component
FGL15_RS07825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGL15_RS07845	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGL15_RS07850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FGL15_RS07870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGL15_RS07915	COG0640	Transcriptional regulator
FGL15_RS07955	COG1051	belongs to the nudix hydrolase family
FGL15_RS07990	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS07995	COG1737	Transcriptional regulator
FGL15_RS08000	COG0477	Major facilitator Superfamily
FGL15_RS08005	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FGL15_RS08010	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FGL15_RS08015	COG0363	glucosamine-6-phosphate deaminase activity
FGL15_RS08020	COG0277	FAD linked oxidase domain protein
FGL15_RS08045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FGL15_RS08140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FGL15_RS08155	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FGL15_RS08175	COG0305	Participates in initiation and elongation during chromosome replication
FGL15_RS08180	COG0359	binds to the 23S rRNA
FGL15_RS08185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FGL15_RS08195	COG0360	Binds together with S18 to 16S ribosomal RNA
FGL15_RS08220	COG1609	Transcriptional regulator
FGL15_RS08225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FGL15_RS08230	COG4221	oxidoreductase activity
FGL15_RS08235	COG3836	Belongs to the HpcH HpaI aldolase family
FGL15_RS08240	COG2267	carboxylic ester hydrolase activity
FGL15_RS08255	COG1175	transmembrane transport
FGL15_RS08275	COG0393	Putative heavy-metal-binding
FGL15_RS08290	COG0601	transmembrane transport
FGL15_RS08300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGL15_RS08310	COG0617	tRNA 3'-terminal CCA addition
FGL15_RS08325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FGL15_RS08335	COG4608	Belongs to the ABC transporter superfamily
FGL15_RS08340	COG0444	Belongs to the ABC transporter superfamily
FGL15_RS08345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL15_RS08350	COG0601	transmembrane transport
FGL15_RS08370	COG0006	proline dipeptidase activity
FGL15_RS08395	COG1362	aminopeptidase activity
FGL15_RS08415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGL15_RS08425	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FGL15_RS08475	COG1309	transcriptional regulator
FGL15_RS08500	COG2261	transglycosylase associated protein
FGL15_RS08505	COG0693	protein deglycase activity
FGL15_RS08515	COG0484	heat shock protein binding
FGL15_RS08520	COG4115	mRNA cleavage
FGL15_RS08530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGL15_RS08580	COG0492	ferredoxin-NADP+ reductase activity
FGL15_RS08585	COG3118	belongs to the thioredoxin family
FGL15_RS08595	COG1192	Involved in chromosome partitioning
FGL15_RS08600	COG0357	Ribosomal RNA small subunit methyltransferase G
FGL15_RS08610	COG0706	membrane insertase activity
FGL15_RS08615	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FGL15_RS08620	COG0594	ribonuclease P activity
FGL15_RS08625	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FGL15_RS08630	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FGL15_RS08635	COG0592	DNA-directed DNA polymerase activity
FGL15_RS08645	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FGL15_RS08650	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FGL15_RS08655	COG0187	DNA topoisomerase II activity
FGL15_RS08660	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FGL15_RS08825	COG1051	belongs to the nudix hydrolase family
FGL15_RS08840	COG0705	Rhomboid family
FGL15_RS08840	COG0457	Tetratricopeptide repeat
FGL15_RS08850	COG3764	Sortase (surface protein transpeptidase)
FGL15_RS08865	COG0515	serine threonine protein kinase
FGL15_RS08870	COG0768	penicillin binding
FGL15_RS08885	COG1716	ATPase activity
FGL15_RS08910	COG1476	TRANSCRIPTIONal
FGL15_RS08930	COG2205	protein histidine kinase activity
FGL15_RS08950	COG0246	Mannitol dehydrogenase
FGL15_RS08960	COG0477	Major facilitator Superfamily
FGL15_RS08965	COG4948	Mandelate Racemase Muconate Lactonizing
FGL15_RS09005	COG0395	ABC-type sugar transport system, permease component
FGL15_RS09035	COG1175	transmembrane transport
FGL15_RS09040	COG0395	ABC-type sugar transport system, permease component
FGL15_RS09055	COG1609	Transcriptional regulator
FGL15_RS09100	COG3458	cephalosporin-C deacetylase activity
FGL15_RS09125	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FGL15_RS09155	COG0667	Aldo Keto reductase
FGL15_RS09190	COG1573	uracil-dna glycosylase
FGL15_RS09195	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FGL15_RS09220	COG0488	(ABC) transporter
FGL15_RS09230	COG2814	Major facilitator Superfamily
FGL15_RS09245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGL15_RS09250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGL15_RS09255	COG0494	nUDIX hydrolase
FGL15_RS09270	COG0183	Belongs to the thiolase family
FGL15_RS09275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FGL15_RS09280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FGL15_RS09290	COG0667	Aldo Keto reductase
FGL15_RS09300	COG1012	belongs to the aldehyde dehydrogenase family
FGL15_RS09315	COG0667	Aldo Keto reductase
FGL15_RS09395	COG0314	molybdopterin synthase activity
FGL15_RS09400	COG0521	Mo-molybdopterin cofactor biosynthetic process
FGL15_RS09400	COG0315	cyclic pyranopterin monophosphate synthase activity
FGL15_RS09420	COG1309	transcriptional regulator
FGL15_RS09435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGL15_RS09440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FGL15_RS09460	COG1940	carbohydrate kinase activity
FGL15_RS09485	COG1609	Transcriptional regulator
FGL15_RS09500	COG1082	Xylose isomerase domain protein TIM barrel
FGL15_RS09505	COG0395	ABC-type sugar transport system, permease component
FGL15_RS09510	COG1175	transmembrane transport
FGL15_RS09520	COG1904	glucuronate isomerase
FGL15_RS09530	COG4948	Mandelate Racemase Muconate Lactonizing
FGL15_RS09545	COG1414	Transcriptional regulator
FGL15_RS09560	COG0800	Aldolase
FGL15_RS09565	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FGL15_RS09570	COG2610	gluconate transmembrane transporter activity
FGL15_RS09580	COG0738	Major facilitator superfamily
FGL15_RS09585	COG1609	Transcriptional regulator
FGL15_RS09595	COG0393	Putative heavy-metal-binding
FGL15_RS09610	COG4585	Histidine kinase
FGL15_RS09645	COG3590	peptidase
FGL15_RS09650	COG0137	argininosuccinate synthase activity
FGL15_RS09655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGL15_RS09660	COG0673	inositol 2-dehydrogenase activity
FGL15_RS09665	COG1126	abc transporter atp-binding protein
FGL15_RS09670	COG0765	amino acid transport
FGL15_RS09675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL15_RS09685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FGL15_RS09690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FGL15_RS09700	COG0673	inositol 2-dehydrogenase activity
FGL15_RS09710	COG0395	ABC-type sugar transport system, permease component
FGL15_RS09730	COG1609	Transcriptional regulator
FGL15_RS09735	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FGL15_RS09740	COG0423	glycine-tRNA ligase activity
FGL15_RS09755	COG0604	alcohol dehydrogenase
FGL15_RS09755	COG3321	synthase
FGL15_RS09760	COG2409	Drug exporters of the RND superfamily
FGL15_RS09780	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FGL15_RS09795	COG3250	beta-galactosidase activity
FGL15_RS09805	COG4172	Belongs to the ABC transporter superfamily
FGL15_RS09810	COG0444	Belongs to the ABC transporter superfamily
FGL15_RS09815	COG0601	transmembrane transport
FGL15_RS09835	COG2249	NAD(P)H dehydrogenase (quinone) activity
FGL15_RS09855	COG0698	ribose 5-phosphate isomerase
FGL15_RS09860	COG0149	triose-phosphate isomerase activity
FGL15_RS09865	COG1082	Xylose isomerase domain protein TIM barrel
FGL15_RS09870	COG2084	Dehydrogenase
FGL15_RS09900	COG1597	lipid kinase activity
FGL15_RS09905	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FGL15_RS09990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FGL15_RS10050	COG1175	transmembrane transport
FGL15_RS10055	COG0395	ABC-type sugar transport system, permease component
FGL15_RS10070	COG4941	Belongs to the sigma-70 factor family
FGL15_RS10075	COG3795	YCII-related domain
FGL15_RS10110	COG1175	transmembrane transport
FGL15_RS10115	COG0395	ABC-type sugar transport system, permease component
FGL15_RS10125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FGL15_RS10135	COG0583	DNA-binding transcription factor activity
FGL15_RS10175	COG0640	Transcriptional regulator
FGL15_RS10205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGL15_RS10210	COG0318	PFAM AMP-dependent synthetase and ligase
FGL15_RS10215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGL15_RS10220	COG0596	Alpha beta hydrolase
FGL15_RS10255	COG1309	transcriptional regulator
FGL15_RS10265	COG2161	toxin-antitoxin pair type II binding
FGL15_RS10280	COG4585	Histidine kinase
FGL15_RS10285	COG2197	response regulator
FGL15_RS10295	COG1309	transcriptional regulator
FGL15_RS10300	COG1064	alcohol dehydrogenase
FGL15_RS10315	COG1357	PFAM Pentapeptide repeats (8 copies)
FGL15_RS10350	COG4221	oxidoreductase activity
FGL15_RS10355	COG3250	beta-galactosidase activity
FGL15_RS10360	COG3250	beta-galactosidase activity
FGL15_RS10375	COG0640	Transcriptional regulator
FGL15_RS10405	COG0596	Alpha beta hydrolase
FGL15_RS10420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FGL15_RS10435	COG0303	'Molybdopterin
FGL15_RS10440	COG0303	'Molybdopterin
FGL15_RS10535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGL15_RS10550	COG1122	ATPase activity
FGL15_RS10555	COG0183	Belongs to the thiolase family
FGL15_RS10565	COG1268	BioY protein
FGL15_RS10580	COG1864	DNA RNA non-specific endonuclease
FGL15_RS10580	COG3591	Belongs to the peptidase S1B family
FGL15_RS10595	COG0395	ABC-type sugar transport system, permease component
FGL15_RS10610	COG1063	alcohol dehydrogenase
FGL15_RS10620	COG0789	Transcriptional regulator
FGL15_RS10660	COG1971	Probably functions as a manganese efflux pump
FGL15_RS10665	COG2814	Major facilitator Superfamily
FGL15_RS10670	COG2197	response regulator
FGL15_RS10675	COG4585	Histidine kinase
FGL15_RS10680	COG0577	efflux transmembrane transporter activity
FGL15_RS10680	COG1136	(ABC) transporter
FGL15_RS10685	COG0577	efflux transmembrane transporter activity
FGL15_RS10685	COG1136	(ABC) transporter
FGL15_RS10690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGL15_RS10710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGL15_RS10720	COG1131	(ABC) transporter
FGL15_RS10735	COG4585	Histidine kinase
FGL15_RS10740	COG2197	response regulator
FGL15_RS10775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS10780	COG1120	ATPase activity
FGL15_RS10790	COG0384	phenazine biosynthesis protein PhzF
FGL15_RS10820	COG4209	transmembrane transport
FGL15_RS10825	COG0395	ABC-type sugar transport system, permease component
FGL15_RS10845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGL15_RS10850	COG0583	DNA-binding transcription factor activity
FGL15_RS10855	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FGL15_RS10870	COG4585	Histidine kinase
FGL15_RS10875	COG2197	response regulator
FGL15_RS10890	COG2211	Major facilitator Superfamily
FGL15_RS10895	COG0657	acetylesterase activity
FGL15_RS10900	COG0657	acetylesterase activity
FGL15_RS10905	COG1609	Transcriptional regulator
FGL15_RS10940	COG0789	Transcriptional regulator
FGL15_RS10945	COG2315	Protein conserved in bacteria
FGL15_RS10955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGL15_RS10985	COG1609	Transcriptional regulator
FGL15_RS11035	COG0659	secondary active sulfate transmembrane transporter activity
FGL15_RS11075	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FGL15_RS11075	COG1672	PFAM Archaeal ATPase
FGL15_RS11090	COG0702	epimerase
FGL15_RS11095	COG2501	S4 domain
FGL15_RS11105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGL15_RS11140	COG0514	ATP-dependent DNA helicase (RecQ)
FGL15_RS11170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGL15_RS11180	COG1522	sequence-specific DNA binding
FGL15_RS11210	COG1473	amidohydrolase
FGL15_RS11255	COG4221	oxidoreductase activity
FGL15_RS11260	COG4221	oxidoreductase activity
FGL15_RS11275	COG1902	pentaerythritol trinitrate reductase activity
FGL15_RS11280	COG1309	transcriptional regulator
FGL15_RS11305	COG0477	Major facilitator Superfamily
FGL15_RS11345	COG1609	Transcriptional regulator
FGL15_RS11355	COG1175	transmembrane transport
FGL15_RS11360	COG0395	ABC-type sugar transport system, permease component
FGL15_RS11380	COG1482	cell wall glycoprotein biosynthetic process
FGL15_RS11415	COG0531	amino acid
FGL15_RS11420	COG1609	Transcriptional regulator
FGL15_RS11430	COG1175	transmembrane transport
FGL15_RS11435	COG0395	ABC-type sugar transport system, permease component
FGL15_RS11440	COG3250	beta-galactosidase activity
FGL15_RS11455	COG0738	Major facilitator superfamily
FGL15_RS11475	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FGL15_RS11480	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FGL15_RS11485	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FGL15_RS11510	COG3546	catalase activity
FGL15_RS11520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGL15_RS11530	COG2207	Transcriptional regulator
FGL15_RS11535	COG2814	Major facilitator Superfamily
FGL15_RS11540	COG1309	transcriptional regulator
FGL15_RS11545	COG2409	Drug exporters of the RND superfamily
FGL15_RS11550	COG0259	pyridoxamine-phosphate oxidase activity
FGL15_RS11585	COG0444	Belongs to the ABC transporter superfamily
FGL15_RS11605	COG1120	ATPase activity
FGL15_RS11610	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS11615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS11620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FGL15_RS11625	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FGL15_RS11640	COG1309	transcriptional regulator
FGL15_RS11645	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS11655	COG0673	inositol 2-dehydrogenase activity
FGL15_RS11695	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS11730	COG0531	amino acid
FGL15_RS11750	COG0506	proline dehydrogenase activity
FGL15_RS11785	COG0444	Belongs to the ABC transporter superfamily
FGL15_RS11790	COG4172	Belongs to the ABC transporter superfamily
FGL15_RS11795	COG0601	transmembrane transport
FGL15_RS11825	COG0783	Belongs to the Dps family
FGL15_RS11835	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS11840	COG3387	PFAM Glycoside hydrolase 15-related
FGL15_RS11850	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS11855	COG1295	ribonuclease BN
FGL15_RS11870	COG2514	catechol 2,3-dioxygenase activity
FGL15_RS11875	COG0400	carboxylic ester hydrolase activity
FGL15_RS11895	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FGL15_RS11930	COG2267	carboxylic ester hydrolase activity
FGL15_RS11935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGL15_RS11945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGL15_RS11950	COG1131	(ABC) transporter
FGL15_RS11995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGL15_RS12015	COG0179	Fumarylacetoacetate (FAA) hydrolase
FGL15_RS12025	COG3971	2-oxopent-4-enoate hydratase activity
FGL15_RS12030	COG0477	Major facilitator Superfamily
FGL15_RS12035	COG1414	Transcriptional regulator
FGL15_RS12040	COG0823	Involved in the tonB-independent uptake of proteins
FGL15_RS12075	COG4221	oxidoreductase activity
FGL15_RS12100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGL15_RS12115	COG1175	transmembrane transport
FGL15_RS12120	COG0395	ABC-type sugar transport system, permease component
FGL15_RS12135	COG1739	Uncharacterized protein family UPF0029
FGL15_RS12165	COG2197	response regulator
FGL15_RS12200	COG0717	Belongs to the dCTP deaminase family
FGL15_RS12215	COG0697	spore germination
FGL15_RS12225	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FGL15_RS12230	COG0142	geranyltranstransferase activity
FGL15_RS12260	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FGL15_RS12265	COG1609	Transcriptional regulator
FGL15_RS12270	COG4166	transmembrane transport
FGL15_RS12275	COG0601	transmembrane transport
FGL15_RS12280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL15_RS12285	COG4172	Belongs to the ABC transporter superfamily
FGL15_RS12305	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS12310	COG0179	Fumarylacetoacetate (FAA) hydrolase
FGL15_RS12315	COG4948	Mandelate Racemase Muconate Lactonizing
FGL15_RS12355	COG0542	response to heat
FGL15_RS12370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FGL15_RS12375	COG0484	heat shock protein binding
FGL15_RS12380	COG0789	Transcriptional regulator
FGL15_RS12395	COG2813	Specifically methylates the guanine in position
FGL15_RS12405	COG3739	integral membrane protein
FGL15_RS12415	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FGL15_RS12430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGL15_RS12440	COG1122	ATPase activity
FGL15_RS12450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGL15_RS12465	COG1120	ATPase activity
FGL15_RS12470	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS12475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS12485	COG0542	response to heat
FGL15_RS12510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGL15_RS12545	COG4152	abc transporter atp-binding protein
FGL15_RS12550	COG0667	Aldo Keto reductase
FGL15_RS12555	COG2197	response regulator
FGL15_RS12560	COG4585	Histidine kinase
FGL15_RS12560	COG2203	Gaf domain
FGL15_RS12570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGL15_RS12580	COG1116	anion transmembrane transporter activity
FGL15_RS12585	COG1309	transcriptional regulator
FGL15_RS12595	COG2130	NADP-dependent
FGL15_RS12625	COG0586	Pfam SNARE associated Golgi protein
FGL15_RS12630	COG0583	DNA-binding transcription factor activity
FGL15_RS12640	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS12645	COG1012	belongs to the aldehyde dehydrogenase family
FGL15_RS12650	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FGL15_RS12655	COG0174	glutamine synthetase
FGL15_RS12660	COG0833	amino acid
FGL15_RS12665	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FGL15_RS12675	COG1063	alcohol dehydrogenase
FGL15_RS12720	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FGL15_RS12755	COG3842	ATPase activity
FGL15_RS12770	COG1136	(ABC) transporter
FGL15_RS12770	COG0577	efflux transmembrane transporter activity
FGL15_RS12800	COG1121	(ABC) transporter
FGL15_RS12805	COG0287	Prephenate dehydrogenase
FGL15_RS12805	COG1605	Chorismate mutase
FGL15_RS12815	COG2188	Transcriptional regulator
FGL15_RS12830	COG1175	transmembrane transport
FGL15_RS12835	COG0395	ABC-type sugar transport system, permease component
FGL15_RS12840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FGL15_RS12845	COG0604	alcohol dehydrogenase
FGL15_RS12855	COG2409	Drug exporters of the RND superfamily
FGL15_RS12870	COG0577	efflux transmembrane transporter activity
FGL15_RS12870	COG1136	(ABC) transporter
FGL15_RS12875	COG0577	efflux transmembrane transporter activity
FGL15_RS12875	COG1136	(ABC) transporter
FGL15_RS12890	COG0745	RESPONSE REGULATOR receiver
FGL15_RS12895	COG2205	protein histidine kinase activity
FGL15_RS12905	COG1802	Transcriptional regulator
FGL15_RS12915	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGL15_RS12975	COG1733	regulation of RNA biosynthetic process
FGL15_RS12985	COG2084	Dehydrogenase
FGL15_RS13000	COG0047	phosphoribosylformylglycinamidine synthase activity
FGL15_RS13005	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGL15_RS13045	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FGL15_RS13050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGL15_RS13060	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FGL15_RS13065	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FGL15_RS13085	COG1063	alcohol dehydrogenase
FGL15_RS13095	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FGL15_RS13115	COG2267	carboxylic ester hydrolase activity
FGL15_RS13120	COG0151	Belongs to the GarS family
FGL15_RS13145	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FGL15_RS13175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGL15_RS13180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGL15_RS13200	COG0531	amino acid
FGL15_RS13210	COG1695	Transcriptional regulator
FGL15_RS13240	COG4565	transcriptional regulatory protein
FGL15_RS13245	COG3290	protein histidine kinase activity
FGL15_RS13250	COG1301	dicarboxylic acid transport
FGL15_RS13270	COG2986	histidine ammonia-lyase
FGL15_RS13285	COG2207	Transcriptional regulator
FGL15_RS13290	COG3224	Antibiotic biosynthesis monooxygenase
FGL15_RS13305	COG0513	Belongs to the DEAD box helicase family
FGL15_RS13325	COG0456	acetyltransferase
FGL15_RS13335	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FGL15_RS13340	COG1122	ATPase activity
FGL15_RS13385	COG0514	ATP-dependent DNA helicase (RecQ)
FGL15_RS13390	COG1960	acyl-CoA dehydrogenase activity
FGL15_RS13415	COG0726	polysaccharide deacetylase
FGL15_RS13425	COG0438	transferase activity, transferring glycosyl groups
FGL15_RS13460	COG0489	protein tyrosine kinase activity
FGL15_RS13465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGL15_RS13470	COG0438	transferase activity, transferring glycosyl groups
FGL15_RS13495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FGL15_RS13505	COG3883	PFAM NLP P60 protein
FGL15_RS13505	COG0791	NLP P60 protein
FGL15_RS13550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGL15_RS13575	COG3585	molybdate ion transport
FGL15_RS13600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGL15_RS13640	COG0739	heme binding
FGL15_RS13640	COG1196	nuclear chromosome segregation
FGL15_RS13640	COG0741	lytic transglycosylase activity
FGL15_RS13645	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FGL15_RS13660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGL15_RS13665	COG0302	gtp cyclohydrolase
FGL15_RS13675	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FGL15_RS13705	COG2259	Doxx family
FGL15_RS13710	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FGL15_RS13720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGL15_RS13740	COG0248	Ppx GppA phosphatase
FGL15_RS13745	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FGL15_RS13750	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FGL15_RS13755	COG0737	Belongs to the 5'-nucleotidase family
FGL15_RS13770	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FGL15_RS13860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGL15_RS13865	COG0025	NhaP-type Na H and K H
FGL15_RS13880	COG0463	Glycosyl transferase, family 2
FGL15_RS13930	COG0318	PFAM AMP-dependent synthetase and ligase
FGL15_RS13945	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FGL15_RS13950	COG1201	RNA secondary structure unwinding
FGL15_RS13980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL15_RS13995	COG4608	Belongs to the ABC transporter superfamily
FGL15_RS14005	COG0006	proline dipeptidase activity
FGL15_RS14010	COG1802	Transcriptional regulator
FGL15_RS14035	COG3938	Belongs to the proline racemase family
FGL15_RS14050	COG1673	EVE domain
FGL15_RS14065	COG2318	DinB family
FGL15_RS14095	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FGL15_RS14110	COG0085	RNA polymerase activity
FGL15_RS14225	COG0714	Associated with various cellular activities
FGL15_RS14250	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FGL15_RS14255	COG0049	tRNA binding
FGL15_RS14260	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGL15_RS14265	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGL15_RS14275	COG0051	transcription antitermination factor activity, RNA binding
FGL15_RS14280	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FGL15_RS14285	COG0088	Forms part of the polypeptide exit tunnel
FGL15_RS14290	COG0089	rRNA binding
FGL15_RS14295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FGL15_RS14300	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FGL15_RS14305	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FGL15_RS14310	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FGL15_RS14315	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FGL15_RS14320	COG0255	Belongs to the universal ribosomal protein uL29 family
FGL15_RS14325	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FGL15_RS14330	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FGL15_RS14335	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FGL15_RS14340	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FGL15_RS14345	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FGL15_RS14350	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FGL15_RS14355	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FGL15_RS14360	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FGL15_RS14365	COG1841	ribosomal large subunit assembly
FGL15_RS14370	COG0200	Binds to the 23S rRNA
FGL15_RS14380	COG0563	adenylate kinase activity
FGL15_RS14385	COG0024	Methionine aminopeptidase
FGL15_RS14395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FGL15_RS14400	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FGL15_RS14405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FGL15_RS14415	COG0202	RNA polymerase activity
FGL15_RS14420	COG0203	ribosomal protein L17
FGL15_RS14430	COG0101	tRNA pseudouridine synthase activity
FGL15_RS14440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FGL15_RS14445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGL15_RS14450	COG1072	(Pantothenic acid kinase))
FGL15_RS14455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FGL15_RS14460	COG0736	holo-[acyl-carrier-protein] synthase activity
FGL15_RS14465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGL15_RS14470	COG0802	atpase or kinase
FGL15_RS14475	COG0456	acetyltransferase
FGL15_RS14475	COG1214	PFAM Peptidase M22, glycoprotease
FGL15_RS14480	COG0456	acetyltransferase
FGL15_RS14485	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FGL15_RS14500	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FGL15_RS14550	COG0516	GMP reductase activity
FGL15_RS14555	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FGL15_RS14565	COG0475	glutathione-regulated potassium exporter activity
FGL15_RS14580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FGL15_RS14580	COG0519	Catalyzes the synthesis of GMP from XMP
FGL15_RS14590	COG0584	glycerophosphoryl diester phosphodiesterase
FGL15_RS14630	COG0138	bifunctional purine biosynthesis protein purh
FGL15_RS14645	COG1132	(ABC) transporter
FGL15_RS14650	COG1132	(ABC) transporter
FGL15_RS14675	COG0538	isocitrate dehydrogenase activity
FGL15_RS14685	COG1175	transmembrane transport
FGL15_RS14690	COG0395	ABC-type sugar transport system, permease component
FGL15_RS14700	COG1940	carbohydrate kinase activity
FGL15_RS14715	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FGL15_RS14735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGL15_RS14740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGL15_RS14755	COG0246	Mannitol dehydrogenase
FGL15_RS14805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FGL15_RS14810	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FGL15_RS14815	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FGL15_RS14860	COG1309	transcriptional regulator
FGL15_RS14885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FGL15_RS14910	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FGL15_RS14915	COG0454	-acetyltransferase
FGL15_RS14915	COG0456	acetyltransferase
FGL15_RS14920	COG0745	RESPONSE REGULATOR receiver
FGL15_RS14930	COG4044	May play a role in the intracellular transport of hydrophobic ligands
FGL15_RS14935	COG0354	folic acid binding
FGL15_RS14950	COG0588	phosphoglycerate mutase activity
FGL15_RS14970	COG5002	protein histidine kinase activity
FGL15_RS14975	COG0745	RESPONSE REGULATOR receiver
FGL15_RS14990	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FGL15_RS14990	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FGL15_RS15000	COG0215	cysteine-tRNA ligase activity
FGL15_RS15015	COG3842	ATPase activity
FGL15_RS15040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGL15_RS15060	COG0459	protein refolding
FGL15_RS15085	COG0745	RESPONSE REGULATOR receiver
FGL15_RS15090	COG1061	Type III restriction enzyme res subunit
FGL15_RS15115	COG1278	Cold shock
FGL15_RS15135	COG1388	LysM domain
FGL15_RS15135	COG3942	CHAP domain
FGL15_RS15160	COG4565	transcriptional regulatory protein
FGL15_RS15165	COG3290	protein histidine kinase activity
FGL15_RS15170	COG2851	Citrate transporter
FGL15_RS15185	COG0438	transferase activity, transferring glycosyl groups
FGL15_RS15205	COG1970	mechanosensitive ion channel activity
FGL15_RS15220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGL15_RS15265	COG0477	Major facilitator Superfamily
FGL15_RS15280	COG2017	converts alpha-aldose to the beta-anomer
FGL15_RS15285	COG0477	Major facilitator Superfamily
FGL15_RS15295	COG2733	membrane
FGL15_RS15300	COG1937	Protein conserved in bacteria
FGL15_RS15315	COG0596	Alpha beta hydrolase
FGL15_RS15325	COG0431	NADPH-dependent FMN reductase
FGL15_RS15335	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FGL15_RS15340	COG1780	Probably involved in ribonucleotide reductase function
FGL15_RS15345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGL15_RS15350	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGL15_RS15380	COG1643	Atp-dependent helicase
FGL15_RS15400	COG1131	(ABC) transporter
FGL15_RS15410	COG2986	histidine ammonia-lyase
FGL15_RS15425	COG1174	glycine betaine transport
FGL15_RS15440	COG1331	Highly conserved protein containing a thioredoxin domain
FGL15_RS15450	COG1760	l-serine dehydratase
FGL15_RS15470	COG1832	CoA-binding protein
FGL15_RS15475	COG2873	o-acetylhomoserine
FGL15_RS15485	COG2855	membrane
FGL15_RS15500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL15_RS15505	COG0084	hydrolase, TatD family'
FGL15_RS15510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FGL15_RS15515	COG0667	Aldo Keto reductase
FGL15_RS15520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FGL15_RS15540	COG0300	oxidoreductase activity
FGL15_RS15550	COG0277	FAD linked oxidase domain protein
FGL15_RS15555	COG1597	lipid kinase activity
FGL15_RS15560	COG1309	transcriptional regulator
FGL15_RS15570	COG0488	(ABC) transporter
FGL15_RS15580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGL15_RS15585	COG2011	ABC-type metal ion transport system permease component
FGL15_RS15600	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FGL15_RS15605	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGL15_RS15610	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FGL15_RS15615	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGL15_RS15620	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FGL15_RS15625	COG0193	aminoacyl-tRNA hydrolase activity
FGL15_RS15640	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FGL15_RS15650	COG0596	Alpha beta hydrolase
FGL15_RS15655	COG1012	belongs to the aldehyde dehydrogenase family
FGL15_RS15665	COG0124	histidyl-tRNA synthetase
FGL15_RS15675	COG0148	phosphopyruvate hydratase activity
FGL15_RS15690	COG1404	Belongs to the peptidase S8 family
FGL15_RS15745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGL15_RS15765	COG2211	Major facilitator Superfamily
FGL15_RS15780	COG1704	LemA family
FGL15_RS15795	COG3214	Protein conserved in bacteria
FGL15_RS15805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FGL15_RS15810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGL15_RS15835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FGL15_RS15845	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FGL15_RS15855	COG0114	fumarate hydratase activity
FGL15_RS15875	COG1570	exodeoxyribonuclease VII activity
FGL15_RS15890	COG0191	fructose-bisphosphate aldolase activity
FGL15_RS15895	COG1494	fructose-1,6-bisphosphatase
FGL15_RS15905	COG1322	Protein conserved in bacteria
FGL15_RS15960	COG0488	(ABC) transporter
FGL15_RS15980	COG1104	cysteine desulfurase activity
FGL15_RS15990	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FGL15_RS15995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FGL15_RS16005	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FGL15_RS16010	COG0509	glycine decarboxylation via glycine cleavage system
FGL15_RS16015	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGL15_RS16015	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGL15_RS16030	COG0601	transmembrane transport
FGL15_RS16035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL15_RS16070	COG1217	gtp-binding protein TYPA
FGL15_RS16080	COG2837	iron assimilation
FGL15_RS16085	COG2822	iron ion transport
FGL15_RS16115	COG2171	N-acyltransferase activity
FGL15_RS16120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGL15_RS16140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGL15_RS16155	COG2239	Acts as a magnesium transporter
FGL15_RS16165	COG0006	proline dipeptidase activity
FGL15_RS16175	COG0613	PHP domain protein
FGL15_RS16180	COG0513	Belongs to the DEAD box helicase family
FGL15_RS16205	COG0210	DNA helicase
FGL15_RS16235	COG3480	Lon protease (S16) C-terminal proteolytic domain
FGL15_RS16240	COG1615	UPF0182 protein
FGL15_RS16255	COG1522	sequence-specific DNA binding
FGL15_RS16260	COG4175	Glycine betaine
FGL15_RS16260	COG0517	IMP dehydrogenase activity
FGL15_RS16265	COG4176	ABC-type proline glycine betaine transport system permease component
FGL15_RS16280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGL15_RS16310	COG0438	transferase activity, transferring glycosyl groups
FGL15_RS16330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FGL15_RS16355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FGL15_RS16360	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FGL15_RS16365	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FGL15_RS16375	COG0586	Pfam SNARE associated Golgi protein
FGL15_RS16390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FGL15_RS16505	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FGL15_RS16510	COG2884	Cell division ATP-binding protein ftsE
FGL15_RS16515	COG2177	Part of the ABC transporter FtsEX involved in
FGL15_RS16520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FGL15_RS16530	COG2111	Na H antiporter
FGL15_RS16530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FGL15_RS16535	COG1006	Multisubunit Na H antiporter MnhC subunit
FGL15_RS16540	COG0651	ATP synthesis coupled electron transport
FGL15_RS16550	COG2212	antiporter activity
FGL15_RS16555	COG1320	monovalent cation:proton antiporter activity
FGL15_RS16570	COG0483	inositol monophosphate 1-phosphatase activity
FGL15_RS16590	COG1082	Xylose isomerase domain protein TIM barrel
FGL15_RS16600	COG0561	phosphatase activity
FGL15_RS16600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGL15_RS16605	COG0129	dihydroxy-acid dehydratase activity
FGL15_RS16615	COG0440	acetolactate synthase activity
FGL15_RS16620	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FGL15_RS16640	COG1737	Transcriptional regulator
FGL15_RS16645	COG4821	SIS domain
FGL15_RS16650	COG1653	transport
FGL15_RS16665	COG3142	Participates in the control of copper homeostasis
FGL15_RS16695	COG0477	Major facilitator Superfamily
FGL15_RS16700	COG0473	3-isopropylmalate dehydrogenase activity
FGL15_RS16705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGL15_RS16710	COG0179	Fumarylacetoacetate (FAA) hydrolase
FGL15_RS16715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGL15_RS16720	COG0583	DNA-binding transcription factor activity
FGL15_RS16725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGL15_RS16740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGL15_RS16745	COG0489	protein tyrosine kinase activity
FGL15_RS16755	COG0587	DNA-directed DNA polymerase activity
FGL15_RS16775	COG1278	Cold shock
FGL15_RS16790	COG1597	lipid kinase activity
FGL15_RS16815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FGL15_RS16820	COG0066	3-isopropylmalate dehydratase activity
FGL15_RS16825	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGL15_RS16830	COG0204	Acyl-transferase
FGL15_RS16830	COG0318	PFAM AMP-dependent synthetase and ligase
FGL15_RS16835	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FGL15_RS16840	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGL15_RS16855	COG0742	ribosomal rna small subunit methyltransferase
FGL15_RS16860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FGL15_RS16865	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FGL15_RS16875	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FGL15_RS16880	COG0571	ribonuclease III activity
FGL15_RS16885	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FGL15_RS16890	COG0456	acetyltransferase
FGL15_RS16900	COG0552	protein localization to endoplasmic reticulum
FGL15_RS16910	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FGL15_RS16915	COG0321	lipoyl(octanoyl) transferase activity
FGL15_RS16930	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FGL15_RS16935	COG0228	four-way junction DNA binding
FGL15_RS16940	COG1837	Belongs to the UPF0109 family
FGL15_RS16945	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FGL15_RS16950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGL15_RS16955	COG0243	molybdopterin cofactor binding
FGL15_RS16960	COG2223	nitrite transmembrane transporter activity
FGL15_RS16970	COG1648	precorrin-2 dehydrogenase activity
FGL15_RS16970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGL15_RS16975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGL15_RS16990	COG0336	Belongs to the RNA methyltransferase TrmD family
FGL15_RS17005	COG3850	Histidine kinase
FGL15_RS17010	COG2197	response regulator
FGL15_RS17020	COG0335	large ribosomal subunit rRNA binding
FGL15_RS17025	COG0681	Belongs to the peptidase S26 family
FGL15_RS17030	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FGL15_RS17040	COG0792	nuclease activity
FGL15_RS17195	COG4974	Belongs to the 'phage' integrase family
FGL15_RS17205	COG0052	Belongs to the universal ribosomal protein uS2 family
FGL15_RS17210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FGL15_RS17215	COG0528	UMP kinase activity
FGL15_RS17220	COG0233	cytoplasmic translational termination
FGL15_RS17255	COG3118	belongs to the thioredoxin family
FGL15_RS17260	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FGL15_RS17265	COG0366	Alpha amylase catalytic
FGL15_RS17275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FGL15_RS17290	COG0482	sulfurtransferase activity
FGL15_RS17295	COG0477	Major facilitator Superfamily
FGL15_RS17300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGL15_RS17305	COG0318	PFAM AMP-dependent synthetase and ligase
FGL15_RS17310	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGL15_RS17315	COG0154	amidase activity
FGL15_RS17320	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGL15_RS17335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGL15_RS17345	COG4721	ABC-type cobalt transport system, permease component
FGL15_RS17350	COG1122	ATPase activity
FGL15_RS17375	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FGL15_RS17390	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FGL15_RS17430	COG1946	Acyl-CoA thioesterase
FGL15_RS17450	COG0668	transmembrane transport
FGL15_RS17455	COG2197	response regulator
FGL15_RS17460	COG4585	Histidine kinase
FGL15_RS17470	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FGL15_RS17475	COG0698	ribose 5-phosphate isomerase
FGL15_RS17500	COG0783	Belongs to the Dps family
FGL15_RS17535	COG0544	peptidyl-prolyl cis-trans isomerase activity
FGL15_RS17545	COG0740	serine-type endopeptidase activity
FGL15_RS17550	COG0740	serine-type endopeptidase activity
FGL15_RS17555	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FGL15_RS17560	COG0339	signal peptide processing
FGL15_RS17575	COG0525	valine-tRNA ligase activity
FGL15_RS17580	COG2755	lipolytic protein G-D-S-L family
FGL15_RS17580	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FGL15_RS17595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL15_RS17615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FGL15_RS17620	COG0285	dihydrofolate synthase activity
FGL15_RS17640	COG1530	ribonuclease E activity
FGL15_RS17650	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FGL15_RS17655	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FGL15_RS17660	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FGL15_RS17665	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FGL15_RS17670	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FGL15_RS17680	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FGL15_RS17690	COG0799	negative regulation of ribosome biogenesis
FGL15_RS17705	COG2814	Major facilitator Superfamily
FGL15_RS17710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGL15_RS17720	COG3424	synthase
FGL15_RS17740	COG2353	YceI-like domain
FGL15_RS17745	COG4129	membrane
FGL15_RS17760	COG1271	oxidase subunit
FGL15_RS17765	COG1294	oxidase, subunit
FGL15_RS17770	COG4988	ABC transporter
FGL15_RS17775	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FGL15_RS17780	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FGL15_RS17780	COG0512	Glutamine amidotransferase of anthranilate synthase
FGL15_RS17785	COG0495	leucyl-tRNA aminoacylation
FGL15_RS17795	COG1596	polysaccharide export
FGL15_RS17795	COG1555	photosystem II stabilization
FGL15_RS17810	COG0268	Binds directly to 16S ribosomal RNA
FGL15_RS17815	COG0481	GTPase activity
FGL15_RS17835	COG1420	regulation of RNA biosynthetic process
FGL15_RS17840	COG0484	heat shock protein binding
FGL15_RS17850	COG0537	adenosine 5'-monophosphoramidase activity
FGL15_RS17860	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FGL15_RS17870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FGL15_RS17880	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FGL15_RS17885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGL15_RS17890	COG4585	Histidine kinase
FGL15_RS17895	COG2197	response regulator
FGL15_RS17900	COG1136	(ABC) transporter
FGL15_RS17900	COG0577	efflux transmembrane transporter activity
FGL15_RS17905	COG1136	(ABC) transporter
FGL15_RS17905	COG0577	efflux transmembrane transporter activity
FGL15_RS17915	COG1381	Involved in DNA repair and RecF pathway recombination
FGL15_RS17920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FGL15_RS17925	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGL15_RS17930	COG0442	prolyl-tRNA aminoacylation
FGL15_RS17945	COG0358	DNA primase activity
FGL15_RS17950	COG4608	Belongs to the ABC transporter superfamily
FGL15_RS17970	COG0438	transferase activity, transferring glycosyl groups
FGL15_RS17995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGL15_RS18000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGL15_RS18015	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FGL15_RS18030	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FGL15_RS18075	COG3962	Belongs to the TPP enzyme family
FGL15_RS18085	COG0673	inositol 2-dehydrogenase activity
FGL15_RS18090	COG1082	Xylose isomerase domain protein TIM barrel
FGL15_RS18100	COG2814	Major facilitator Superfamily
FGL15_RS18110	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGL15_RS18120	COG1942	4-Oxalocrotonate Tautomerase
FGL15_RS18125	COG2188	Transcriptional regulator
FGL15_RS18130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGL15_RS18165	COG1175	transmembrane transport
FGL15_RS18170	COG0395	ABC-type sugar transport system, permease component
FGL15_RS18190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGL15_RS18200	COG3321	synthase
FGL15_RS18200	COG0604	alcohol dehydrogenase
FGL15_RS18205	COG1309	transcriptional regulator
FGL15_RS18235	COG1522	sequence-specific DNA binding
FGL15_RS18260	COG0640	Transcriptional regulator
FGL15_RS18270	COG1335	isochorismatase
FGL15_RS18285	COG1132	(ABC) transporter
FGL15_RS18295	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS18300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS18305	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FGL15_RS18340	COG1216	Glycosyl transferase, family 2
FGL15_RS18345	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS18385	COG0583	DNA-binding transcription factor activity
FGL15_RS18430	COG1940	carbohydrate kinase activity
FGL15_RS18440	COG1175	transmembrane transport
FGL15_RS18445	COG0395	ABC-type sugar transport system, permease component
FGL15_RS18450	COG0366	Alpha amylase catalytic
FGL15_RS18465	COG1132	(ABC) transporter
FGL15_RS18470	COG1132	(ABC) transporter
FGL15_RS18475	COG1120	ATPase activity
FGL15_RS18480	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS18485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL15_RS18530	COG1349	DNA-binding transcription factor activity
FGL15_RS18535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGL15_RS18545	COG3345	alpha-galactosidase
FGL15_RS18575	COG0395	ABC-type sugar transport system, permease component
FGL15_RS18580	COG1472	Belongs to the glycosyl hydrolase 3 family
FGL15_RS18600	COG1597	lipid kinase activity
FGL15_RS18615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGL15_RS18620	COG2873	o-acetylhomoserine
FGL15_RS18650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FGL15_RS18660	COG2017	converts alpha-aldose to the beta-anomer
FGL15_RS18670	COG1764	response to oxidative stress
FGL15_RS18675	COG0583	DNA-binding transcription factor activity
FGL15_RS18685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FGL15_RS18720	COG0174	glutamine synthetase
FGL15_RS18725	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FGL15_RS18745	COG2815	serine threonine protein kinase
FGL15_RS18745	COG0515	serine threonine protein kinase
FGL15_RS18755	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGL15_RS18760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGL15_RS18780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGL15_RS18800	COG0187	DNA topoisomerase II activity
FGL15_RS18805	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FGL15_RS18830	COG0756	dUTP diphosphatase activity
FGL15_RS18845	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FGL15_RS18850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FGL15_RS18860	COG0667	Aldo Keto reductase
FGL15_RS18865	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGL15_RS18865	COG1024	Enoyl-CoA hydratase
FGL15_RS18870	COG0183	Belongs to the thiolase family
FGL15_RS18965	COG0297	glycogen (starch) synthase activity
FGL15_RS18995	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FGL15_RS19000	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FGL15_RS19065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FGL15_RS19075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FGL15_RS19080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FGL15_RS19085	COG0217	transcriptional regulatory protein
FGL15_RS19090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FGL15_RS19095	COG0632	four-way junction helicase activity
FGL15_RS19100	COG2255	four-way junction helicase activity
FGL15_RS19110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGL15_RS19115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGL15_RS19120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGL15_RS19130	COG1196	nuclear chromosome segregation
FGL15_RS19145	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FGL15_RS19155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGL15_RS19160	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FGL15_RS19170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FGL15_RS19175	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FGL15_RS19180	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGL15_RS19185	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FGL15_RS19190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FGL15_RS19195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FGL15_RS19200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGL15_RS19205	COG0346	lactoylglutathione lyase activity
FGL15_RS19210	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FGL15_RS19215	COG0540	Belongs to the ATCase OTCase family
FGL15_RS19220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FGL15_RS19230	COG0505	Belongs to the CarA family
FGL15_RS19235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGL15_RS19240	COG0284	orotidine-5'-phosphate decarboxylase activity
FGL15_RS19245	COG0194	GDP metabolic process
FGL15_RS19250	COG1758	RNA polymerase activity
FGL15_RS19255	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FGL15_RS19265	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGL15_RS19275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FGL15_RS19280	COG0140	phosphoribosyl-ATP diphosphatase activity
FGL15_RS19285	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FGL15_RS19290	COG0107	imidazoleglycerol-phosphate synthase activity
FGL15_RS19295	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FGL15_RS19310	COG0134	indole-3-glycerol-phosphate synthase activity
FGL15_RS19315	COG0133	tryptophan synthase activity
FGL15_RS19320	COG0159	tryptophan synthase activity
FGL15_RS19325	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FGL15_RS19330	COG0067	glutamate synthase
FGL15_RS19330	COG0069	glutamate synthase activity
FGL15_RS19330	COG0070	glutamate synthase
FGL15_RS19350	COG0406	alpha-ribazole phosphatase activity
FGL15_RS19370	COG2050	protein possibly involved in aromatic compounds catabolism
FGL15_RS19385	COG1090	epimerase
FGL15_RS19395	COG0237	dephospho-CoA kinase activity
FGL15_RS19400	COG0556	nucleotide-excision repair
FGL15_RS19420	COG1481	regulation of sporulation
FGL15_RS19435	COG0126	phosphoglycerate kinase activity
FGL15_RS19440	COG0149	triose-phosphate isomerase activity
FGL15_RS19445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FGL15_RS19455	COG0363	glucosamine-6-phosphate deaminase activity
FGL15_RS19470	COG0166	Belongs to the GPI family
FGL15_RS19475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGL15_RS19485	COG0109	protoheme IX farnesyltransferase activity
FGL15_RS19495	COG1612	heme a metabolic process
FGL15_RS19510	COG2146	nitrite reductase [NAD(P)H] activity
FGL15_RS19515	COG0396	ATPase activity
FGL15_RS19520	COG2151	metal-sulfur cluster biosynthetic enzyme
FGL15_RS19525	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FGL15_RS19530	COG0488	(ABC) transporter
FGL15_RS19550	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS19560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FGL15_RS19565	COG0297	glycogen (starch) synthase activity
FGL15_RS19570	COG1119	ATPase activity
FGL15_RS19575	COG0254	rRNA binding
FGL15_RS19620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGL15_RS19625	COG1968	undecaprenyl-diphosphatase activity
FGL15_RS19630	COG0215	cysteine-tRNA ligase activity
FGL15_RS19655	COG2378	regulation of single-species biofilm formation
FGL15_RS19665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGL15_RS19670	COG0805	protein transport
FGL15_RS19675	COG4581	dead DEAH box helicase
FGL15_RS19690	COG0584	glycerophosphoryl diester phosphodiesterase
FGL15_RS19705	COG1028	Short-chain dehydrogenase reductase Sdr
FGL15_RS19715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGL15_RS19720	COG2197	response regulator
FGL15_RS19725	COG4585	Histidine kinase
FGL15_RS19735	COG1131	(ABC) transporter
FGL15_RS19740	COG1309	transcriptional regulator
FGL15_RS19750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGL15_RS19750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGL15_RS19750	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FGL15_RS19755	COG1461	Dihydroxyacetone kinase
FGL15_RS19760	COG2376	Dihydroxyacetone kinase
FGL15_RS19765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FGL15_RS19770	COG1845	cytochrome c oxidase, subunit III
FGL15_RS19775	COG2010	Cytochrome c
FGL15_RS19780	COG0723	plastoquinol--plastocyanin reductase activity
FGL15_RS19785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FGL15_RS19800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FGL15_RS19805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FGL15_RS19825	COG0167	dihydroorotate dehydrogenase activity
FGL15_RS19830	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FGL15_RS19835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FGL15_RS19850	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FGL15_RS19855	COG3599	regulation of cell shape
FGL15_RS19865	COG1799	cell septum assembly
FGL15_RS19870	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FGL15_RS19890	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGL15_RS19900	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FGL15_RS19905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGL15_RS19915	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FGL15_RS19930	COG0275	rRNA processing
FGL15_RS19935	COG2001	Belongs to the MraZ family
FGL15_RS19945	COG0142	geranyltranstransferase activity
FGL15_RS19955	COG2815	serine threonine protein kinase
FGL15_RS19955	COG0515	serine threonine protein kinase
FGL15_RS19960	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FGL15_RS19970	COG1940	carbohydrate kinase activity
FGL15_RS20005	COG1716	ATPase activity
FGL15_RS20025	COG2357	RelA SpoT domain protein
FGL15_RS20070	COG0514	ATP-dependent DNA helicase (RecQ)
FGL15_RS20080	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FGL15_RS20090	COG2197	response regulator