locus-tag	class	description
A8H26_RS00010	COG0501	Belongs to the peptidase M48B family
A8H26_RS00025	COG1166	arginine decarboxylase activity
A8H26_RS00045	COG0477	Major facilitator Superfamily
A8H26_RS00050	COG1609	Transcriptional regulator
A8H26_RS00065	COG2814	Major facilitator Superfamily
A8H26_RS00070	COG0814	amino acid
A8H26_RS00080	COG3091	SprT-like family
A8H26_RS00085	COG2356	endonuclease I
A8H26_RS00090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A8H26_RS00095	COG0189	ligase activity
A8H26_RS00105	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A8H26_RS00110	COG2197	response regulator
A8H26_RS00115	COG2805	Type II/IV secretion system protein
A8H26_RS00120	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A8H26_RS00125	COG0762	integral membrane protein
A8H26_RS00135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A8H26_RS00140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A8H26_RS00150	COG0252	asparaginase activity
A8H26_RS00160	COG3171	Protein conserved in bacteria
A8H26_RS00170	COG1194	a g-specific adenine glycosylase
A8H26_RS00185	COG1982	Orn Lys Arg decarboxylase major
A8H26_RS00190	COG1811	Na channel or pump
A8H26_RS00200	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
A8H26_RS00210	COG0210	DNA helicase
A8H26_RS00295	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A8H26_RS00300	COG1393	Belongs to the ArsC family
A8H26_RS00305	COG3039	Transposase
A8H26_RS00315	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS00320	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A8H26_RS00325	COG1902	pentaerythritol trinitrate reductase activity
A8H26_RS00330	COG3118	belongs to the thioredoxin family
A8H26_RS00335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8H26_RS00360	COG3328	transposase activity
A8H26_RS00365	COG2801	Transposase and inactivated derivatives
A8H26_RS00380	COG3209	COG3209 Rhs family protein
A8H26_RS00390	COG2368	4-hydroxyphenylacetate
A8H26_RS00395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A8H26_RS00405	COG1566	PFAM secretion protein HlyD family protein
A8H26_RS00415	COG5457	Domain of unknown function (DUF1127)
A8H26_RS00420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8H26_RS00440	COG4977	sequence-specific DNA binding
A8H26_RS00440	COG1917	Cupin 2, conserved barrel domain protein
A8H26_RS00450	COG2271	Major facilitator Superfamily
A8H26_RS00455	COG1335	isochorismatase
A8H26_RS00460	COG2375	cellular response to nickel ion
A8H26_RS00465	COG1695	Transcriptional regulator
A8H26_RS00480	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS00485	COG0446	pyridine nucleotide-disulphide oxidoreductase
A8H26_RS00485	COG1902	pentaerythritol trinitrate reductase activity
A8H26_RS00520	COG3525	Glycosyl hydrolase, family 20, catalytic domain
A8H26_RS00530	COG1609	Transcriptional regulator
A8H26_RS00535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8H26_RS00535	COG1263	PTS System
A8H26_RS00540	COG0366	Alpha amylase catalytic
A8H26_RS00545	COG1858	cytochrome C peroxidase
A8H26_RS00580	COG2026	Addiction module toxin, RelE StbE family
A8H26_RS00585	COG3077	Addiction module antitoxin, RelB DinJ family
A8H26_RS00590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8H26_RS00590	COG3711	transcriptional antiterminator
A8H26_RS00595	COG2706	6-phosphogluconolactonase activity
A8H26_RS00610	COG3964	amidohydrolase
A8H26_RS00640	COG0697	spore germination
A8H26_RS00650	COG0312	modulator of DNA gyrase
A8H26_RS00685	COG0531	amino acid
A8H26_RS00695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A8H26_RS00735	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8H26_RS00740	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8H26_RS00745	COG1129	ABC transporter
A8H26_RS00750	COG1879	ABC-type sugar transport system periplasmic component
A8H26_RS00775	COG3025	triphosphatase activity
A8H26_RS00780	COG4991	sh3 domain protein
A8H26_RS00795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A8H26_RS00805	COG0477	Major facilitator Superfamily
A8H26_RS00820	COG0829	nickel cation binding
A8H26_RS00840	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
A8H26_RS00850	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A8H26_RS00855	COG3177	Filamentation induced by cAMP protein fic
A8H26_RS00870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A8H26_RS00875	COG0358	DNA primase activity
A8H26_RS00895	COG3663	DNA glycosylase
A8H26_RS00910	COG2801	Transposase and inactivated derivatives
A8H26_RS00940	COG0372	Belongs to the citrate synthase family
A8H26_RS00950	COG3829	transcription factor binding
A8H26_RS00955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A8H26_RS00955	COG2169	Transcriptional regulator
A8H26_RS00990	COG2084	Dehydrogenase
A8H26_RS00995	COG4774	siderophore transport
A8H26_RS00995	COG1629	transport
A8H26_RS01045	COG0582	viral genome integration into host DNA
A8H26_RS01055	COG1175	transmembrane transport
A8H26_RS01060	COG0395	ABC-type sugar transport system, permease component
A8H26_RS01065	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A8H26_RS01070	COG3842	ATPase activity
A8H26_RS01080	COG0288	reversible hydration of carbon dioxide
A8H26_RS01085	COG0659	secondary active sulfate transmembrane transporter activity
A8H26_RS01090	COG1064	alcohol dehydrogenase
A8H26_RS01100	COG0433	COG0433 Predicted ATPase
A8H26_RS01105	COG0795	lipopolysaccharide-transporting ATPase activity
A8H26_RS01110	COG0795	lipopolysaccharide-transporting ATPase activity
A8H26_RS01120	COG2927	DNA polymerase III (CHI subunit)
A8H26_RS01165	COG2813	Specifically methylates the guanine in position
A8H26_RS01170	COG1451	nucleotide metabolic process
A8H26_RS01175	COG0673	inositol 2-dehydrogenase activity
A8H26_RS01180	COG0861	Integral membrane protein TerC family
A8H26_RS01195	COG2721	sulfolactate sulfo-lyase activity
A8H26_RS01205	COG2271	Major facilitator Superfamily
A8H26_RS01210	COG2186	Transcriptional regulator
A8H26_RS01215	COG0586	Pfam SNARE associated Golgi protein
A8H26_RS01225	COG1422	Protein of unknown function (DUF1090)
A8H26_RS01230	COG4575	ribosome binding
A8H26_RS01235	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
A8H26_RS01245	COG2259	Doxx family
A8H26_RS01250	COG0435	Glutathione S-transferase
A8H26_RS01255	COG0583	DNA-binding transcription factor activity
A8H26_RS01260	COG1741	Belongs to the pirin family
A8H26_RS01265	COG2841	Protein conserved in bacteria
A8H26_RS01280	COG1349	DNA-binding transcription factor activity
A8H26_RS01290	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8H26_RS01300	COG3716	PTS system mannose fructose sorbose family IID component
A8H26_RS01305	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8H26_RS01310	COG2222	sugar isomerase
A8H26_RS01325	COG3122	Protein conserved in bacteria
A8H26_RS01335	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A8H26_RS01340	COG3107	peptidoglycan biosynthetic process
A8H26_RS01345	COG0792	nuclease activity
A8H26_RS01355	COG2823	Periplasmic or secreted lipoprotein
A8H26_RS01360	COG0701	Predicted permease
A8H26_RS01365	COG0702	epimerase
A8H26_RS01370	COG0693	protein deglycase activity
A8H26_RS01385	COG3153	acetyltransferase
A8H26_RS01390	COG3154	lipid carrier protein
A8H26_RS01395	COG0826	peptidase U32
A8H26_RS01400	COG0826	peptidase U32
A8H26_RS01405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8H26_RS01410	COG0814	amino acid
A8H26_RS01415	COG0513	Belongs to the DEAD box helicase family
A8H26_RS01435	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A8H26_RS01455	COG0195	Participates in both transcription termination and antitermination
A8H26_RS01460	COG0779	Required for maturation of 30S ribosomal subunits
A8H26_RS01480	COG0668	transmembrane transport
A8H26_RS01510	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A8H26_RS01520	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A8H26_RS01540	COG1534	Rna-binding protein
A8H26_RS01545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A8H26_RS01550	COG2027	D-alanyl-D-alanine carboxypeptidase
A8H26_RS01560	COG0697	spore germination
A8H26_RS01575	COG0142	geranyltranstransferase activity
A8H26_RS01580	COG3423	Transcriptional regulator
A8H26_RS01590	COG5007	Belongs to the BolA IbaG family
A8H26_RS01595	COG3113	response to antibiotic
A8H26_RS01600	COG2854	intermembrane phospholipid transfer
A8H26_RS01605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A8H26_RS01610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A8H26_RS01615	COG1127	ABC transporter
A8H26_RS01620	COG0530	calcium, potassium:sodium antiporter activity
A8H26_RS01625	COG0517	IMP dehydrogenase activity
A8H26_RS01625	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A8H26_RS01630	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A8H26_RS01635	COG3117	lipopolysaccharide transmembrane transporter activity
A8H26_RS01640	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A8H26_RS01645	COG1137	ATPase activity
A8H26_RS01650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A8H26_RS01665	COG1660	Displays ATPase and GTPase activities
A8H26_RS01670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8H26_RS01675	COG0515	serine threonine protein kinase
A8H26_RS01685	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
A8H26_RS01690	COG5002	protein histidine kinase activity
A8H26_RS01690	COG2198	Histidine kinase
A8H26_RS01690	COG0784	Response regulator, receiver
A8H26_RS01695	COG1242	4 iron, 4 sulfur cluster binding
A8H26_RS01705	COG0070	glutamate synthase
A8H26_RS01705	COG0069	glutamate synthase activity
A8H26_RS01705	COG0067	glutamate synthase
A8H26_RS01710	COG0493	'glutamate synthase
A8H26_RS01715	COG2969	positive regulation of protein catabolic process
A8H26_RS01720	COG0625	glutathione transferase activity
A8H26_RS01745	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A8H26_RS01750	COG3105	Protein conserved in bacteria
A8H26_RS01755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8H26_RS01760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8H26_RS01765	COG0039	L-malate dehydrogenase activity
A8H26_RS01785	COG2732	(Barnase) inhibitor
A8H26_RS01790	COG1289	transmembrane transporter activity
A8H26_RS01805	COG0583	DNA-binding transcription factor activity
A8H26_RS01810	COG0312	modulator of DNA gyrase
A8H26_RS01815	COG3164	Protein of unknown function
A8H26_RS01830	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A8H26_RS01835	COG1792	Involved in formation and maintenance of cell shape
A8H26_RS01840	COG1077	Cell shape determining protein MreB Mrl
A8H26_RS01850	COG2199	diguanylate cyclase activity
A8H26_RS01850	COG2200	EAL domain
A8H26_RS01855	COG0604	alcohol dehydrogenase
A8H26_RS01875	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A8H26_RS01885	COG0511	ligase activity, forming carbon-carbon bonds
A8H26_RS01890	COG0439	Biotin carboxylase
A8H26_RS01895	COG3924	membrane
A8H26_RS01900	COG4145	pantothenate transmembrane transporter activity
A8H26_RS01930	COG4626	Terminase
A8H26_RS01930	COG1802	Transcriptional regulator
A8H26_RS02020	COG3561	AntA/AntB antirepressor
A8H26_RS02035	COG0582	viral genome integration into host DNA
A8H26_RS02045	COG0738	Major facilitator superfamily
A8H26_RS02055	COG1349	DNA-binding transcription factor activity
A8H26_RS02075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8H26_RS02080	COG4597	amino acid ABC transporter
A8H26_RS02085	COG0765	amino acid transport
A8H26_RS02090	COG1126	abc transporter atp-binding protein
A8H26_RS02095	COG2801	Transposase and inactivated derivatives
A8H26_RS02140	COG0151	Belongs to the GarS family
A8H26_RS02145	COG0058	SHG alpha-glucan phosphorylase activity
A8H26_RS02170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A8H26_RS02175	COG2095	MarC family integral membrane protein
A8H26_RS02180	COG3121	Chaperone
A8H26_RS02195	COG3121	Chaperone
A8H26_RS02205	COG2610	gluconate transmembrane transporter activity
A8H26_RS02210	COG3265	gluconokinase activity
A8H26_RS02215	COG1609	Transcriptional regulator
A8H26_RS02220	COG1741	Belongs to the pirin family
A8H26_RS02230	COG1247	-acetyltransferase
A8H26_RS02235	COG0405	Gamma-glutamyltransferase
A8H26_RS02245	COG0584	glycerophosphoryl diester phosphodiesterase
A8H26_RS02255	COG0395	ABC-type sugar transport system, permease component
A8H26_RS02275	COG0410	ABC transporter
A8H26_RS02280	COG0411	ABC transporter
A8H26_RS02285	COG4177	L-phenylalanine transmembrane transporter activity
A8H26_RS02295	COG0683	leucine binding
A8H26_RS02305	COG0683	leucine binding
A8H26_RS02315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A8H26_RS02325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A8H26_RS02330	COG2177	Part of the ABC transporter FtsEX involved in
A8H26_RS02335	COG2884	Cell division ATP-binding protein ftsE
A8H26_RS02340	COG0552	protein localization to endoplasmic reticulum
A8H26_RS02345	COG0742	ribosomal rna small subunit methyltransferase
A8H26_RS02350	COG3776	membrane
A8H26_RS02360	COG3714	YhhN family
A8H26_RS02375	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A8H26_RS02385	COG0477	Major facilitator Superfamily
A8H26_RS02405	COG1515	deoxyribonuclease V activity
A8H26_RS02410	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A8H26_RS02420	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
A8H26_RS02435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A8H26_RS02440	COG2104	thiamine diphosphate biosynthetic process
A8H26_RS02450	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A8H26_RS02470	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A8H26_RS02520	COG0250	Participates in transcription elongation, termination and antitermination
A8H26_RS02525	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A8H26_RS02580	COG2194	sulfuric ester hydrolase activity
A8H26_RS02585	COG4993	Dehydrogenase
A8H26_RS02590	COG2223	nitrite transmembrane transporter activity
A8H26_RS02595	COG5571	outer membrane autotransporter
A8H26_RS02600	COG2818	Glycosylase
A8H26_RS02605	COG0456	acetyltransferase
A8H26_RS02610	COG0243	molybdopterin cofactor binding
A8H26_RS02615	COG2885	chlorophyll binding
A8H26_RS02620	COG1609	Transcriptional regulator
A8H26_RS02630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8H26_RS02650	COG2814	Major facilitator Superfamily
A8H26_RS02655	COG2944	sequence-specific DNA binding
A8H26_RS02675	COG3274	enterobacterial common antigen metabolic process
A8H26_RS02690	COG1070	Carbohydrate kinase
A8H26_RS02705	COG4213	ABC transporter substrate-binding protein
A8H26_RS02715	COG4214	carbohydrate transport
A8H26_RS02720	COG1609	Transcriptional regulator
A8H26_RS02720	COG2207	Transcriptional regulator
A8H26_RS02725	COG2992	FlgJ-related protein
A8H26_RS02730	COG0366	Alpha amylase catalytic
A8H26_RS02735	COG3977	Valine--pyruvate aminotransferase
A8H26_RS02750	COG1566	PFAM secretion protein HlyD family protein
A8H26_RS02755	COG2814	Major facilitator Superfamily
A8H26_RS02760	COG1454	alcohol dehydrogenase
A8H26_RS02765	COG1012	belongs to the aldehyde dehydrogenase family
A8H26_RS02770	COG3276	selenocysteine insertion sequence binding
A8H26_RS02790	COG0583	DNA-binding transcription factor activity
A8H26_RS02810	COG3722	fumarate hydratase activity
A8H26_RS02815	COG0583	DNA-binding transcription factor activity
A8H26_RS02830	COG2186	Transcriptional regulator
A8H26_RS02845	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A8H26_RS02865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A8H26_RS02870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8H26_RS02875	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A8H26_RS02880	COG4942	peptidase
A8H26_RS02885	COG2861	carbohydrate metabolic process
A8H26_RS02890	COG2982	Protein involved in outer membrane biogenesis
A8H26_RS02895	COG2200	EAL domain
A8H26_RS02900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8H26_RS02905	COG0612	Peptidase, M16
A8H26_RS02915	COG2199	diguanylate cyclase activity
A8H26_RS02915	COG2200	EAL domain
A8H26_RS02920	COG0457	Tetratricopeptide repeat
A8H26_RS02920	COG3118	belongs to the thioredoxin family
A8H26_RS02925	COG1215	transferase activity, transferring glycosyl groups
A8H26_RS02930	COG1215	transferase activity, transferring glycosyl groups
A8H26_RS02975	COG1215	transferase activity, transferring glycosyl groups
A8H26_RS02985	COG2894	cell division
A8H26_RS02995	COG4608	Belongs to the ABC transporter superfamily
A8H26_RS03000	COG0444	Belongs to the ABC transporter superfamily
A8H26_RS03005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8H26_RS03010	COG0601	transmembrane transport
A8H26_RS03015	COG0747	negative chemotaxis
A8H26_RS03025	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A8H26_RS03025	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A8H26_RS03030	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A8H26_RS03055	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
A8H26_RS03065	COG1739	Uncharacterized protein family UPF0029
A8H26_RS03080	COG1250	3-hydroxyacyl-CoA dehydrogenase
A8H26_RS03080	COG1024	Enoyl-CoA hydratase
A8H26_RS03110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8H26_RS03115	COG1126	abc transporter atp-binding protein
A8H26_RS03120	COG0235	Class ii aldolase
A8H26_RS03150	COG0805	protein transport
A8H26_RS03165	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A8H26_RS03185	COG2944	sequence-specific DNA binding
A8H26_RS03200	COG0412	Dienelactone hydrolase
A8H26_RS03215	COG0583	DNA-binding transcription factor activity
A8H26_RS03220	COG0697	spore germination
A8H26_RS03225	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A8H26_RS03230	COG0561	phosphatase activity
A8H26_RS03235	COG2267	carboxylic ester hydrolase activity
A8H26_RS03240	COG1280	lysine exporter protein (LysE YggA)
A8H26_RS03245	COG1280	lysine exporter protein (LysE YggA)
A8H26_RS03270	COG0598	Magnesium transport protein CorA
A8H26_RS03275	COG0210	DNA helicase
A8H26_RS03280	COG1011	Hydrolase
A8H26_RS03300	COG5567	small periplasmic lipoprotein
A8H26_RS03310	COG3072	Adenylate cyclase
A8H26_RS03325	COG2959	enzyme of heme biosynthesis
A8H26_RS03330	COG3071	HemY protein
A8H26_RS03375	COG2244	polysaccharide biosynthetic process
A8H26_RS03380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A8H26_RS03385	COG0456	acetyltransferase
A8H26_RS03390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A8H26_RS03395	COG1088	dTDP-glucose 4,6-dehydratase activity
A8H26_RS03400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A8H26_RS03405	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A8H26_RS03410	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
A8H26_RS03415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A8H26_RS03420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A8H26_RS03425	COG3118	belongs to the thioredoxin family
A8H26_RS03435	COG0248	Ppx GppA phosphatase
A8H26_RS03440	COG0210	DNA helicase
A8H26_RS03445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8H26_RS03470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A8H26_RS03475	COG3978	acetolactate synthase activity
A8H26_RS03495	COG3085	chromosome segregation
A8H26_RS03545	COG4206	TonB-dependent receptor
A8H26_RS03550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A8H26_RS03565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8H26_RS03570	COG0583	DNA-binding transcription factor activity
A8H26_RS03585	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A8H26_RS03600	COG2194	sulfuric ester hydrolase activity
A8H26_RS03605	COG2207	Transcriptional regulator
A8H26_RS03610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8H26_RS03615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8H26_RS03620	COG1882	Formate acetyltransferase
A8H26_RS03625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8H26_RS03630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8H26_RS03635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A8H26_RS03635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8H26_RS03635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8H26_RS03645	COG0371	Dehydrogenase
A8H26_RS03650	COG0697	spore germination
A8H26_RS03660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A8H26_RS03665	COG0460	homoserine dehydrogenase
A8H26_RS03665	COG0527	aspartate kinase activity
A8H26_RS03670	COG0626	cystathionine gamma-synthase activity
A8H26_RS03685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A8H26_RS03690	COG1609	Transcriptional regulator
A8H26_RS03695	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A8H26_RS03710	COG1575	Belongs to the MenA family. Type 1 subfamily
A8H26_RS03715	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A8H26_RS03730	COG3678	ATP-independent chaperone mediated protein folding
A8H26_RS03735	COG0745	RESPONSE REGULATOR receiver
A8H26_RS03740	COG2205	protein histidine kinase activity
A8H26_RS03745	COG2258	MOSC domain
A8H26_RS03760	COG4977	sequence-specific DNA binding
A8H26_RS03760	COG1917	Cupin 2, conserved barrel domain protein
A8H26_RS03785	COG1454	alcohol dehydrogenase
A8H26_RS03795	COG2211	Major facilitator Superfamily
A8H26_RS03815	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A8H26_RS03835	COG3383	formate dehydrogenase (NAD+) activity
A8H26_RS03835	COG0243	molybdopterin cofactor binding
A8H26_RS03840	COG0243	molybdopterin cofactor binding
A8H26_RS03840	COG3383	formate dehydrogenase (NAD+) activity
A8H26_RS03845	COG0437	4 iron, 4 sulfur cluster binding
A8H26_RS03850	COG2864	formate dehydrogenase
A8H26_RS03865	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A8H26_RS03875	COG0456	acetyltransferase
A8H26_RS03880	COG1490	D-aminoacyl-tRNA deacylase activity
A8H26_RS03885	COG1295	ribonuclease BN
A8H26_RS03890	COG1011	Hydrolase
A8H26_RS03910	COG3852	Histidine kinase
A8H26_RS03945	COG0204	Acyl-transferase
A8H26_RS03955	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A8H26_RS03960	COG3084	Protein conserved in bacteria
A8H26_RS03965	COG0746	molybdenum cofactor guanylyltransferase activity
A8H26_RS03970	COG1763	Mo-molybdopterin cofactor biosynthetic process
A8H26_RS03995	COG2186	Transcriptional regulator
A8H26_RS04000	COG0477	Major facilitator Superfamily
A8H26_RS04005	COG1609	Transcriptional regulator
A8H26_RS04010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8H26_RS04020	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8H26_RS04025	COG1129	ABC transporter
A8H26_RS04030	COG1869	D-ribose catabolic process
A8H26_RS04055	COG1522	sequence-specific DNA binding
A8H26_RS04060	COG0716	FMN binding
A8H26_RS04080	COG3312	ion transport
A8H26_RS04095	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A8H26_RS04115	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A8H26_RS04140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A8H26_RS04145	COG0573	inorganic phosphate transmembrane transporter activity
A8H26_RS04150	COG0581	inorganic phosphate transmembrane transporter activity
A8H26_RS04160	COG0704	Plays a role in the regulation of phosphate uptake
A8H26_RS04165	COG3121	Chaperone
A8H26_RS04175	COG3188	usher protein
A8H26_RS04195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8H26_RS04200	COG2252	PERMEase
A8H26_RS04205	COG0431	NADPH-dependent FMN reductase
A8H26_RS04210	COG2091	lysine biosynthetic process via aminoadipic acid
A8H26_RS04220	COG1121	(ABC) transporter
A8H26_RS04225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8H26_RS04230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8H26_RS04245	COG0706	membrane insertase activity
A8H26_RS04270	COG0592	DNA-directed DNA polymerase activity
A8H26_RS04280	COG0187	DNA topoisomerase II activity
A8H26_RS04285	COG3753	Protein conserved in bacteria
A8H26_RS04290	COG0561	phosphatase activity
A8H26_RS04300	COG2186	Transcriptional regulator
A8H26_RS04305	COG3734	2-keto-3-deoxy-galactonokinase
A8H26_RS04310	COG0800	Aldolase
A8H26_RS04320	COG2271	Major facilitator Superfamily
A8H26_RS04325	COG0823	Involved in the tonB-independent uptake of proteins
A8H26_RS04330	COG5645	(Lipo)protein
A8H26_RS04345	COG2207	Transcriptional regulator
A8H26_RS04350	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A8H26_RS04355	COG3119	arylsulfatase activity
A8H26_RS04360	COG2149	membrane
A8H26_RS04375	COG2814	Major facilitator Superfamily
A8H26_RS04390	COG2723	6-phospho-beta-galactosidase activity
A8H26_RS04400	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A8H26_RS04420	COG0028	Belongs to the TPP enzyme family
A8H26_RS04425	COG0440	acetolactate synthase activity
A8H26_RS04455	COG3842	ATPase activity
A8H26_RS04470	COG0697	spore germination
A8H26_RS04495	COG1309	transcriptional regulator
A8H26_RS04515	COG1464	Belongs to the NlpA lipoprotein family
A8H26_RS04520	COG2807	transmembrane transport
A8H26_RS04530	COG0288	reversible hydration of carbon dioxide
A8H26_RS04535	COG0583	DNA-binding transcription factor activity
A8H26_RS04540	COG0740	serine-type endopeptidase activity
A8H26_RS04545	COG0531	amino acid
A8H26_RS04550	COG1982	Orn Lys Arg decarboxylase major
A8H26_RS04575	COG3962	Belongs to the TPP enzyme family
A8H26_RS04580	COG0673	inositol 2-dehydrogenase activity
A8H26_RS04585	COG1879	ABC-type sugar transport system periplasmic component
A8H26_RS04595	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8H26_RS04600	COG0673	inositol 2-dehydrogenase activity
A8H26_RS04605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8H26_RS04615	COG3718	enzyme involved in inositol metabolism
A8H26_RS04620	COG3153	acetyltransferase
A8H26_RS04645	COG2982	Protein involved in outer membrane biogenesis
A8H26_RS04650	COG2233	PERMEase
A8H26_RS04655	COG0786	glutamate:sodium symporter activity
A8H26_RS04670	COG3074	FtsZ-dependent cytokinesis
A8H26_RS04675	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
A8H26_RS04725	COG3152	Membrane
A8H26_RS04735	COG1494	fructose-1,6-bisphosphatase
A8H26_RS04740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A8H26_RS04745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8H26_RS04750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A8H26_RS04770	COG2860	membrane
A8H26_RS04785	COG0583	DNA-binding transcription factor activity
A8H26_RS04790	COG0435	Glutathione S-transferase
A8H26_RS04800	COG0583	DNA-binding transcription factor activity
A8H26_RS04810	COG4774	siderophore transport
A8H26_RS04860	COG1396	sequence-specific DNA binding
A8H26_RS04895	COG0582	viral genome integration into host DNA
A8H26_RS04900	COG1561	YicC-like family, N-terminal region
A8H26_RS04925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A8H26_RS04935	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A8H26_RS04940	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A8H26_RS04945	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A8H26_RS04955	COG1519	Transferase
A8H26_RS04960	COG0859	PFAM glycosyl transferase family 9
A8H26_RS04965	COG0438	transferase activity, transferring glycosyl groups
A8H26_RS04970	COG0515	serine threonine protein kinase
A8H26_RS04980	COG1442	glycosyl transferase family 8
A8H26_RS04985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A8H26_RS04995	COG3307	-O-antigen
A8H26_RS05000	COG0859	PFAM glycosyl transferase family 9
A8H26_RS05005	COG0859	PFAM glycosyl transferase family 9
A8H26_RS05015	COG0156	8-amino-7-oxononanoate synthase activity
A8H26_RS05025	COG0477	Major facilitator Superfamily
A8H26_RS05030	COG1295	ribonuclease BN
A8H26_RS05035	COG0583	DNA-binding transcription factor activity
A8H26_RS05055	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A8H26_RS05065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8H26_RS05070	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A8H26_RS05075	COG0671	phosphoesterase, PA-phosphatase related
A8H26_RS05080	COG0339	signal peptide processing
A8H26_RS05090	COG3385	transposase activity
A8H26_RS05095	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A8H26_RS05100	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A8H26_RS05105	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A8H26_RS05110	COG2244	polysaccharide biosynthetic process
A8H26_RS05120	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A8H26_RS05130	COG0795	lipopolysaccharide-transporting ATPase activity
A8H26_RS05145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A8H26_RS05155	COG0318	PFAM AMP-dependent synthetase and ligase
A8H26_RS05160	COG0456	acetyltransferase
A8H26_RS05165	COG0589	response to stress
A8H26_RS05175	COG0306	phosphate transporter
A8H26_RS05180	COG2081	HI0933 family
A8H26_RS05185	COG1227	inorganic diphosphatase activity
A8H26_RS05195	COG0148	phosphopyruvate hydratase activity
A8H26_RS05205	COG0583	DNA-binding transcription factor activity
A8H26_RS05210	COG3479	Phenolic acid decarboxylase
A8H26_RS05215	COG2091	lysine biosynthetic process via aminoadipic acid
A8H26_RS05220	COG0628	permease
A8H26_RS05225	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A8H26_RS05230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8H26_RS05240	COG1349	DNA-binding transcription factor activity
A8H26_RS05250	COG0058	SHG alpha-glucan phosphorylase activity
A8H26_RS05255	COG1640	4-alpha-glucanotransferase
A8H26_RS05260	COG2610	gluconate transmembrane transporter activity
A8H26_RS05280	COG3177	Filamentation induced by cAMP protein fic
A8H26_RS05295	COG1918	ferrous iron import across plasma membrane
A8H26_RS05300	COG2183	response to ionizing radiation
A8H26_RS05305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A8H26_RS05330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A8H26_RS05335	COG1011	Hydrolase
A8H26_RS05345	COG0494	nUDIX hydrolase
A8H26_RS05350	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A8H26_RS05355	COG4972	Pilus assembly protein
A8H26_RS05375	COG4796	Type ii and iii secretion system protein
A8H26_RS05385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A8H26_RS05395	COG3266	domain, Protein
A8H26_RS05400	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A8H26_RS05405	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A8H26_RS05415	COG0180	Tryptophanyl-tRNA synthetase
A8H26_RS05430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A8H26_RS05435	COG0402	S-adenosylhomocysteine deaminase activity
A8H26_RS05440	COG0738	Major facilitator superfamily
A8H26_RS05455	COG2184	nucleotidyltransferase activity
A8H26_RS05465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A8H26_RS05470	COG1289	transmembrane transporter activity
A8H26_RS05485	COG1765	OsmC-like protein
A8H26_RS05490	COG3954	Phosphoribulokinase
A8H26_RS05500	COG0429	hydrolase of the alpha beta-hydrolase fold
A8H26_RS05510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A8H26_RS05520	COG0488	(ABC) transporter
A8H26_RS05530	COG0475	glutathione-regulated potassium exporter activity
A8H26_RS05530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A8H26_RS05535	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
A8H26_RS05540	COG1047	Peptidyl-prolyl cis-trans
A8H26_RS05550	COG0545	Peptidyl-prolyl cis-trans isomerase
A8H26_RS05555	COG2964	Protein conserved in bacteria
A8H26_RS05615	COG0051	transcription antitermination factor activity, RNA binding
A8H26_RS05640	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A8H26_RS05655	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A8H26_RS05660	COG0255	Belongs to the universal ribosomal protein uL29 family
A8H26_RS05715	COG0200	Binds to the 23S rRNA
A8H26_RS05720	COG0201	protein transport
A8H26_RS05735	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A8H26_RS05745	COG0202	RNA polymerase activity
A8H26_RS05750	COG0203	ribosomal protein L17
A8H26_RS05760	COG0789	Transcriptional regulator
A8H26_RS05765	COG3036	rescue of stalled ribosome
A8H26_RS05790	COG0242	peptide deformylase activity
A8H26_RS05795	COG0758	DNA mediated transformation
A8H26_RS05800	COG2922	Belongs to the Smg family
A8H26_RS05805	COG0551	DNA topoisomerase type I activity
A8H26_RS05825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A8H26_RS05865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A8H26_RS05900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A8H26_RS05905	COG1187	pseudouridine synthase activity
A8H26_RS05935	COG4650	regulator
A8H26_RS05950	COG1690	Belongs to the RtcB family
A8H26_RS05955	COG3541	Predicted nucleotidyltransferase
A8H26_RS05960	COG0527	aspartate kinase activity
A8H26_RS05985	COG1652	LysM domain
A8H26_RS05990	COG2731	YhcH YjgK YiaL family protein
A8H26_RS05995	COG3265	gluconokinase activity
A8H26_RS06000	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS06005	COG1609	Transcriptional regulator
A8H26_RS06010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A8H26_RS06020	COG4702	Belongs to the UPF0303 family
A8H26_RS06025	COG1349	DNA-binding transcription factor activity
A8H26_RS06030	COG2084	Dehydrogenase
A8H26_RS06035	COG3395	kinase activity
A8H26_RS06040	COG0235	Class ii aldolase
A8H26_RS06045	COG3622	Belongs to the hyi family
A8H26_RS06050	COG2610	gluconate transmembrane transporter activity
A8H26_RS06055	COG3833	ABC-type maltose transport systems, permease component
A8H26_RS06090	COG3161	chorismate lyase activity
A8H26_RS06105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A8H26_RS06110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A8H26_RS06115	COG0534	Mate efflux family protein
A8H26_RS06120	COG3237	CsbD-like
A8H26_RS06125	COG0735	belongs to the Fur family
A8H26_RS06150	COG0305	Participates in initiation and elongation during chromosome replication
A8H26_RS06170	COG1448	Aminotransferase
A8H26_RS06175	COG3700	Belongs to the class B bacterial acid phosphatase family
A8H26_RS06180	COG0432	Pfam Uncharacterised protein family UPF0047
A8H26_RS06185	COG2315	Protein conserved in bacteria
A8H26_RS06315	COG0515	serine threonine protein kinase
A8H26_RS06350	COG3209	COG3209 Rhs family protein
A8H26_RS06370	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A8H26_RS06380	COG0789	Transcriptional regulator
A8H26_RS06400	COG2252	PERMEase
A8H26_RS06405	COG0025	NhaP-type Na H and K H
A8H26_RS06410	COG1263	PTS System
A8H26_RS06410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8H26_RS06415	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A8H26_RS06420	COG0583	DNA-binding transcription factor activity
A8H26_RS06430	COG1346	cytolysis
A8H26_RS06450	COG3162	membrane
A8H26_RS06455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A8H26_RS06460	COG1301	dicarboxylic acid transport
A8H26_RS06465	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
A8H26_RS06490	COG1802	Transcriptional regulator
A8H26_RS06495	COG1113	amino acid transport
A8H26_RS06500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A8H26_RS06505	COG1012	belongs to the aldehyde dehydrogenase family
A8H26_RS06510	COG0579	oxidoreductase
A8H26_RS06520	COG2188	Transcriptional regulator
A8H26_RS06525	COG2824	Alkylphosphonate utilization operon protein PhnA
A8H26_RS06550	COG2197	response regulator
A8H26_RS06555	COG4235	cytochrome complex assembly
A8H26_RS06560	COG1138	Cytochrome C-type biogenesis protein
A8H26_RS06565	COG3301	Polysulphide reductase, NrfD
A8H26_RS06570	COG0437	4 iron, 4 sulfur cluster binding
A8H26_RS06575	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
A8H26_RS06590	COG3062	negative regulation of establishment of protein localization
A8H26_RS06600	COG0437	4 iron, 4 sulfur cluster binding
A8H26_RS06605	COG0348	domain, Protein
A8H26_RS06620	COG3043	anaerobic respiration
A8H26_RS06625	COG3005	denitrification pathway
A8H26_RS06645	COG0583	DNA-binding transcription factor activity
A8H26_RS06650	COG0025	NhaP-type Na H and K H
A8H26_RS06655	COG0438	transferase activity, transferring glycosyl groups
A8H26_RS06670	COG3121	Chaperone
A8H26_RS06740	COG1132	(ABC) transporter
A8H26_RS06745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8H26_RS06760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A8H26_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS06795	COG1309	transcriptional regulator
A8H26_RS06810	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A8H26_RS06815	COG1027	Aspartate ammonia-lyase
A8H26_RS06825	COG3030	protein affecting phage T7 exclusion by the F plasmid
A8H26_RS06830	COG0531	amino acid
A8H26_RS06835	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A8H26_RS06840	COG0459	protein refolding
A8H26_RS06855	COG1509	lysine 2,3-aminomutase activity
A8H26_RS06870	COG5510	response to toxic substance
A8H26_RS06880	COG3040	lipid binding
A8H26_RS06895	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A8H26_RS06900	COG1053	succinate dehydrogenase
A8H26_RS06910	COG3264	Mechanosensitive ion channel
A8H26_RS06910	COG1511	domain protein
A8H26_RS06945	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A8H26_RS06950	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A8H26_RS06950	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A8H26_RS06955	COG0802	atpase or kinase
A8H26_RS06980	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A8H26_RS06985	COG0330	HflC and HflK could
A8H26_RS06990	COG0330	HflC and HflK could
A8H26_RS06995	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
A8H26_RS07010	COG0557	exoribonuclease II activity
A8H26_RS07015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8H26_RS07020	COG1960	acyl-CoA dehydrogenase activity
A8H26_RS07030	COG3650	response to hydrogen peroxide
A8H26_RS07035	COG1073	alpha beta
A8H26_RS07050	COG3539	Fimbrial protein
A8H26_RS07060	COG3188	usher protein
A8H26_RS07065	COG3121	Chaperone
A8H26_RS07075	COG3539	Fimbrial protein
A8H26_RS07085	COG2200	EAL domain
A8H26_RS07105	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A8H26_RS07115	COG3061	Opacity-associated protein A
A8H26_RS07120	COG0545	Peptidyl-prolyl cis-trans isomerase
A8H26_RS07125	COG1113	amino acid transport
A8H26_RS07135	COG0697	spore germination
A8H26_RS07145	COG0456	acetyltransferase
A8H26_RS07150	COG3706	GGDEF domain
A8H26_RS07155	COG1716	ATPase activity
A8H26_RS07155	COG5001	Diguanylate cyclase
A8H26_RS07170	COG0745	RESPONSE REGULATOR receiver
A8H26_RS07175	COG0702	epimerase
A8H26_RS07180	COG1733	regulation of RNA biosynthetic process
A8H26_RS07190	COG1218	3'(2'),5'-bisphosphate nucleotidase
A8H26_RS07195	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A8H26_RS07210	COG1253	flavin adenine dinucleotide binding
A8H26_RS07265	COG0583	DNA-binding transcription factor activity
A8H26_RS07275	COG0729	surface antigen
A8H26_RS07280	COG2911	Protein conserved in bacteria
A8H26_RS07285	COG2105	PFAM AIG2 family protein
A8H26_RS07290	COG0840	transmembrane signaling receptor activity
A8H26_RS07310	COG1815	bacterial-type flagellum-dependent cell motility
A8H26_RS07315	COG1558	bacterial-type flagellum-dependent cell motility
A8H26_RS07345	COG1706	bacterial-type flagellum-dependent cell motility
A8H26_RS07360	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A8H26_RS07390	COG2198	Histidine kinase
A8H26_RS07390	COG0643	Histidine kinase
A8H26_RS07395	COG0835	chemotaxis
A8H26_RS07430	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A8H26_RS07445	COG0745	RESPONSE REGULATOR receiver
A8H26_RS07450	COG2201	protein-glutamate methylesterase activity
A8H26_RS07455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A8H26_RS07460	COG1677	Flagellar hook-basal body complex protein FliE
A8H26_RS07475	COG1317	bacterial-type flagellum organization
A8H26_RS07485	COG2882	bacterial-type flagellum organization
A8H26_RS07490	COG3144	bacterial-type flagellum assembly
A8H26_RS07495	COG1580	Controls the rotational direction of flagella during chemotaxis
A8H26_RS07505	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A8H26_RS07510	COG3190	flagellar
A8H26_RS07525	COG1684	flagellar biosynthetic protein fliR
A8H26_RS07530	COG0840	transmembrane signaling receptor activity
A8H26_RS07550	COG3384	dioxygenase
A8H26_RS07555	COG0754	glutathionylspermidine amidase activity
A8H26_RS07575	COG0494	nUDIX hydrolase
A8H26_RS07580	COG3151	Protein conserved in bacteria
A8H26_RS07585	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A8H26_RS07590	COG3150	esterase
A8H26_RS07595	COG0187	DNA topoisomerase II activity
A8H26_RS07600	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A8H26_RS07605	COG2249	NAD(P)H dehydrogenase (quinone) activity
A8H26_RS07610	COG0642	Histidine kinase
A8H26_RS07620	COG3111	PFAM Bacterial OB fold (BOF) protein
A8H26_RS07635	COG2132	Multicopper oxidase
A8H26_RS07640	COG1032	radical SAM domain protein
A8H26_RS07675	COG0640	Transcriptional regulator
A8H26_RS07695	COG0583	DNA-binding transcription factor activity
A8H26_RS07820	COG1979	alcohol dehydrogenase
A8H26_RS07825	COG2207	Transcriptional regulator
A8H26_RS07835	COG0626	cystathionine gamma-synthase activity
A8H26_RS07845	COG0848	biopolymer transport protein
A8H26_RS07850	COG0667	Aldo Keto reductase
A8H26_RS07855	COG0840	transmembrane signaling receptor activity
A8H26_RS07860	COG0625	glutathione transferase activity
A8H26_RS07870	COG0754	glutathionylspermidine amidase activity
A8H26_RS07885	COG4770	biotin carboxylase activity
A8H26_RS07890	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A8H26_RS07895	COG4336	lyase activity
A8H26_RS07900	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A8H26_RS07905	COG1914	H( )-stimulated, divalent metal cation uptake system
A8H26_RS07920	COG2831	hemolysin activation secretion protein
A8H26_RS07925	COG3210	domain, Protein
A8H26_RS07960	COG3210	domain, Protein
A8H26_RS07970	COG3328	transposase activity
A8H26_RS07975	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A8H26_RS07985	COG4974	Belongs to the 'phage' integrase family
A8H26_RS08005	COG0789	Transcriptional regulator
A8H26_RS08015	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A8H26_RS08020	COG1393	Belongs to the ArsC family
A8H26_RS08025	COG0431	NADPH-dependent FMN reductase
A8H26_RS08060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A8H26_RS08125	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8H26_RS08155	COG0739	heme binding
A8H26_RS08165	COG2132	Multicopper oxidase
A8H26_RS08170	COG3667	copper resistance
A8H26_RS08175	COG2372	response to copper ion
A8H26_RS08180	COG1276	copper resistance
A8H26_RS08185	COG0745	RESPONSE REGULATOR receiver
A8H26_RS08190	COG2205	protein histidine kinase activity
A8H26_RS08195	COG3039	Transposase
A8H26_RS08280	COG3328	transposase activity
A8H26_RS08310	COG3971	2-oxopent-4-enoate hydratase activity
A8H26_RS08325	COG1012	belongs to the aldehyde dehydrogenase family
A8H26_RS08330	COG0179	Fumarylacetoacetate (FAA) hydrolase
A8H26_RS08335	COG1846	Transcriptional regulator
A8H26_RS08355	COG2733	membrane
A8H26_RS08395	COG0738	Major facilitator superfamily
A8H26_RS08400	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A8H26_RS08405	COG3248	Nucleoside-binding outer membrane protein
A8H26_RS08410	COG1609	Transcriptional regulator
A8H26_RS08425	COG1012	belongs to the aldehyde dehydrogenase family
A8H26_RS08435	COG0523	cobalamin synthesis protein
A8H26_RS08440	COG1966	Carbon starvation protein
A8H26_RS08460	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
A8H26_RS08470	COG4145	pantothenate transmembrane transporter activity
A8H26_RS08475	COG3734	2-keto-3-deoxy-galactonokinase
A8H26_RS08480	COG0800	Aldolase
A8H26_RS08485	COG1737	Transcriptional regulator
A8H26_RS08490	COG0840	transmembrane signaling receptor activity
A8H26_RS08510	COG1484	DNA-dependent DNA replication
A8H26_RS08525	COG2966	Psort location CytoplasmicMembrane, score
A8H26_RS08540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A8H26_RS08545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8H26_RS08550	COG4114	ferric iron reductase
A8H26_RS08560	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS08595	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
A8H26_RS08600	COG0456	acetyltransferase
A8H26_RS08605	COG1011	Hydrolase
A8H26_RS08615	COG2823	Periplasmic or secreted lipoprotein
A8H26_RS08620	COG5487	UPF0391 membrane protein
A8H26_RS08625	COG4667	esterase of the alpha-beta hydrolase superfamily
A8H26_RS08630	COG0084	hydrolase, TatD family'
A8H26_RS08640	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A8H26_RS08655	COG3550	peptidyl-serine autophosphorylation
A8H26_RS08665	COG3726	membrane protein affecting hemolysin expression
A8H26_RS08670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A8H26_RS08675	COG0560	Phosphoserine phosphatase
A8H26_RS08690	COG0488	(ABC) transporter
A8H26_RS08700	COG0741	lytic transglycosylase activity
A8H26_RS08720	COG2207	Transcriptional regulator
A8H26_RS08720	COG3708	Transcriptional regulator
A8H26_RS08725	COG3045	CreA protein
A8H26_RS08730	COG0745	RESPONSE REGULATOR receiver
A8H26_RS08740	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A8H26_RS08750	COG0527	aspartate kinase activity
A8H26_RS08750	COG0460	homoserine dehydrogenase
A8H26_RS08760	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A8H26_RS08770	COG1115	amino acid carrier protein
A8H26_RS08780	COG0521	Mo-molybdopterin cofactor biosynthetic process
A8H26_RS08790	COG1584	GPR1 FUN34 yaaH family protein
A8H26_RS08815	COG3775	system Galactitol-specific IIC component
A8H26_RS08830	COG0583	DNA-binding transcription factor activity
A8H26_RS08840	COG0196	riboflavin kinase activity
A8H26_RS08850	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A8H26_RS08855	COG1047	Peptidyl-prolyl cis-trans
A8H26_RS08870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A8H26_RS08885	COG0505	Belongs to the CarA family
A8H26_RS08930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A8H26_RS08940	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A8H26_RS08945	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
A8H26_RS08950	COG0564	pseudouridine synthase activity
A8H26_RS08960	COG0417	DNA replication proofreading
A8H26_RS08965	COG0235	Class ii aldolase
A8H26_RS08980	COG4977	sequence-specific DNA binding
A8H26_RS08985	COG0586	Pfam SNARE associated Golgi protein
A8H26_RS08995	COG1178	ABC-type Fe3 transport system permease component
A8H26_RS09000	COG4143	(ABC) transporter
A8H26_RS09010	COG2814	Major facilitator Superfamily
A8H26_RS09045	COG0028	Belongs to the TPP enzyme family
A8H26_RS09055	COG1609	Transcriptional regulator
A8H26_RS09075	COG0768	penicillin binding
A8H26_RS09080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A8H26_RS09085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A8H26_RS09090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A8H26_RS09100	COG0772	Belongs to the SEDS family
A8H26_RS09115	COG1181	Belongs to the D-alanine--D-alanine ligase family
A8H26_RS09125	COG0849	cell division
A8H26_RS09130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A8H26_RS09150	COG3387	PFAM Glycoside hydrolase 15-related
A8H26_RS09155	COG0494	nUDIX hydrolase
A8H26_RS09170	COG0237	dephospho-CoA kinase activity
A8H26_RS09180	COG1459	type II secretion system
A8H26_RS09185	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A8H26_RS09190	COG4969	Belongs to the N-Me-Phe pilin family
A8H26_RS09205	COG3725	Membrane protein required for beta-lactamase induction
A8H26_RS09210	COG3940	Belongs to the glycosyl hydrolase 43 family
A8H26_RS09215	COG2211	Major facilitator Superfamily
A8H26_RS09220	COG1113	amino acid transport
A8H26_RS09235	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A8H26_RS09240	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8H26_RS09245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8H26_RS09260	COG0583	DNA-binding transcription factor activity
A8H26_RS09265	COG0667	Aldo Keto reductase
A8H26_RS09290	COG1902	pentaerythritol trinitrate reductase activity
A8H26_RS09295	COG1403	HNH endonuclease
A8H26_RS09300	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A8H26_RS09315	COG2132	Multicopper oxidase
A8H26_RS09335	COG2819	hydrolase of the alpha beta superfamily
A8H26_RS09340	COG4771	TonB-dependent receptor
A8H26_RS09345	COG4993	Dehydrogenase
A8H26_RS09360	COG0288	reversible hydration of carbon dioxide
A8H26_RS09365	COG1131	(ABC) transporter
A8H26_RS09370	COG0842	Transport permease protein
A8H26_RS09375	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8H26_RS09380	COG0726	polysaccharide deacetylase
A8H26_RS09395	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A8H26_RS09400	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A8H26_RS09405	COG0617	tRNA 3'-terminal CCA addition
A8H26_RS09425	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A8H26_RS09430	COG1643	Atp-dependent helicase
A8H26_RS09435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A8H26_RS09440	COG4774	siderophore transport
A8H26_RS09445	COG1120	ATPase activity
A8H26_RS09450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8H26_RS09470	COG0316	Belongs to the HesB IscA family
A8H26_RS09475	COG2860	membrane
A8H26_RS09490	COG0232	Belongs to the dGTPase family. Type 2 subfamily
A8H26_RS09495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8H26_RS09525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A8H26_RS09540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A8H26_RS09545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A8H26_RS09550	COG0575	Belongs to the CDS family
A8H26_RS09560	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8H26_RS09565	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
A8H26_RS09570	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A8H26_RS09575	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A8H26_RS09605	COG0346	lactoylglutathione lyase activity
A8H26_RS09610	COG0037	tRNA processing
A8H26_RS09615	COG4568	rho-dependent transcription termination
A8H26_RS09625	COG4681	YaeQ
A8H26_RS09630	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A8H26_RS09635	COG3015	lipoprotein NlpE involved in copper resistance
A8H26_RS09645	COG1720	tRNA m6t6A37 methyltransferase activity
A8H26_RS09660	COG2011	ABC-type metal ion transport system permease component
A8H26_RS09670	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A8H26_RS09705	COG0840	transmembrane signaling receptor activity
A8H26_RS09710	COG0583	DNA-binding transcription factor activity
A8H26_RS09715	COG3021	interspecies interaction between organisms
A8H26_RS09720	COG2226	methyltransferase
A8H26_RS09725	COG0741	lytic transglycosylase activity
A8H26_RS09725	COG1388	LysM domain
A8H26_RS09735	COG2226	methyltransferase
A8H26_RS09765	COG1953	Uracil, thiamine, allantoin
A8H26_RS09810	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A8H26_RS09820	COG2351	hydroxyisourate hydrolase activity
A8H26_RS09830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A8H26_RS09840	COG1960	acyl-CoA dehydrogenase activity
A8H26_RS09850	COG0121	glutamine amidotransferase
A8H26_RS09855	COG3034	peptidoglycan biosynthetic process
A8H26_RS09870	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A8H26_RS09875	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A8H26_RS09890	COG2991	Protein conserved in bacteria
A8H26_RS09895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A8H26_RS09900	COG2195	Cleaves the N-terminal amino acid of tripeptides
A8H26_RS09970	COG0582	viral genome integration into host DNA
A8H26_RS09990	COG3561	AntA/AntB antirepressor
A8H26_RS10075	COG3328	transposase activity
A8H26_RS10165	COG0583	DNA-binding transcription factor activity
A8H26_RS10170	COG2271	Major facilitator Superfamily
A8H26_RS10185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A8H26_RS10190	COG1309	transcriptional regulator
A8H26_RS10205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A8H26_RS10215	COG3842	ATPase activity
A8H26_RS10225	COG1349	DNA-binding transcription factor activity
A8H26_RS10240	COG0745	RESPONSE REGULATOR receiver
A8H26_RS10245	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS10255	COG1609	Transcriptional regulator
A8H26_RS10260	COG4521	taurine ABC transporter
A8H26_RS10265	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A8H26_RS10270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8H26_RS10275	COG2175	clavaminate synthase activity
A8H26_RS10280	COG0113	porphobilinogen synthase activity
A8H26_RS10285	COG3468	outer membrane autotransporter barrel domain protein
A8H26_RS10290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A8H26_RS10295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A8H26_RS10305	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
A8H26_RS10350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A8H26_RS10365	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A8H26_RS10375	COG4126	flavin adenine dinucleotide binding
A8H26_RS10380	COG3123	guanosine phosphorylase activity
A8H26_RS10390	COG1940	carbohydrate kinase activity
A8H26_RS10395	COG0419	ATPase involved in DNA repair
A8H26_RS10400	COG0420	3'-5' exonuclease activity
A8H26_RS10410	COG5002	protein histidine kinase activity
A8H26_RS10425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A8H26_RS10430	COG0366	Alpha amylase catalytic
A8H26_RS10435	COG0583	DNA-binding transcription factor activity
A8H26_RS10440	COG1335	isochorismatase
A8H26_RS10450	COG1228	amidohydrolase
A8H26_RS10455	COG0747	negative chemotaxis
A8H26_RS10460	COG0601	transmembrane transport
A8H26_RS10465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8H26_RS10500	COG0450	alkyl hydroperoxide reductase
A8H26_RS10510	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A8H26_RS10520	COG1862	Preprotein translocase
A8H26_RS10530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A8H26_RS10535	COG3248	Nucleoside-binding outer membrane protein
A8H26_RS10540	COG4238	major outer membrane lipoprotein
A8H26_RS10550	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A8H26_RS10550	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A8H26_RS10565	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A8H26_RS10570	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A8H26_RS10575	COG0667	Aldo Keto reductase
A8H26_RS10585	COG0142	geranyltranstransferase activity
A8H26_RS10600	COG3642	lipopolysaccharide core region biosynthetic process
A8H26_RS10610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A8H26_RS10620	COG2814	Major facilitator Superfamily
A8H26_RS10625	COG0109	protoheme IX farnesyltransferase activity
A8H26_RS10630	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A8H26_RS10635	COG1845	cytochrome c oxidase, subunit III
A8H26_RS10640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A8H26_RS10645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A8H26_RS10650	COG2223	nitrite transmembrane transporter activity
A8H26_RS10655	COG3056	Lipoprotein
A8H26_RS10660	COG0271	Belongs to the BolA IbaG family
A8H26_RS10685	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A8H26_RS10690	COG0776	regulation of translation
A8H26_RS10695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8H26_RS10700	COG1555	photosystem II stabilization
A8H26_RS10705	COG0824	Thioesterase
A8H26_RS10715	COG4533	DNA binding
A8H26_RS10730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A8H26_RS10735	COG1522	sequence-specific DNA binding
A8H26_RS10740	COG1132	(ABC) transporter
A8H26_RS10745	COG1132	(ABC) transporter
A8H26_RS10750	COG0347	Belongs to the P(II) protein family
A8H26_RS10755	COG0004	ammonium transporteR
A8H26_RS10760	COG1946	Acyl-CoA thioesterase
A8H26_RS10765	COG3126	Type III secretion system lipoprotein chaperone (YscW)
A8H26_RS10770	COG3695	enzyme binding
A8H26_RS10825	COG0110	maltose O-acetyltransferase activity
A8H26_RS10840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8H26_RS10845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8H26_RS10850	COG1309	transcriptional regulator
A8H26_RS10855	COG3264	Mechanosensitive ion channel
A8H26_RS10855	COG1196	nuclear chromosome segregation
A8H26_RS10865	COG3923	Primosomal replication protein n
A8H26_RS10870	COG2832	Protein of unknown function (DUF454)
A8H26_RS10890	COG0583	DNA-binding transcription factor activity
A8H26_RS10925	COG1396	sequence-specific DNA binding
A8H26_RS10930	COG3550	peptidyl-serine autophosphorylation
A8H26_RS10935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A8H26_RS10935	COG4651	solute:proton antiporter activity
A8H26_RS10940	COG2223	nitrite transmembrane transporter activity
A8H26_RS10955	COG3735	TraB family
A8H26_RS11005	COG3188	usher protein
A8H26_RS11015	COG1585	Membrane protein implicated in regulation of membrane protease activity
A8H26_RS11020	COG0330	HflC and HflK could
A8H26_RS11025	COG3118	belongs to the thioredoxin family
A8H26_RS11030	COG0300	oxidoreductase activity
A8H26_RS11035	COG2755	lipolytic protein G-D-S-L family
A8H26_RS11040	COG4181	ATPase activity
A8H26_RS11045	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
A8H26_RS11085	COG2885	chlorophyll binding
A8H26_RS11205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A8H26_RS11210	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A8H26_RS11225	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A8H26_RS11230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A8H26_RS11250	COG1988	membrane-bound metal-dependent
A8H26_RS11255	COG2501	S4 domain
A8H26_RS11310	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A8H26_RS11330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A8H26_RS11335	COG1760	l-serine dehydratase
A8H26_RS11340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8H26_RS11345	COG1278	Cold shock
A8H26_RS11370	COG1902	pentaerythritol trinitrate reductase activity
A8H26_RS11370	COG0446	pyridine nucleotide-disulphide oxidoreductase
A8H26_RS11375	COG2181	nitrate reductase activity
A8H26_RS11375	COG0247	lactate metabolic process
A8H26_RS11380	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A8H26_RS11390	COG1301	dicarboxylic acid transport
A8H26_RS11395	COG0583	DNA-binding transcription factor activity
A8H26_RS11415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8H26_RS11415	COG1017	nitric oxide dioxygenase activity
A8H26_RS11420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A8H26_RS11455	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
A8H26_RS11480	COG3121	Chaperone
A8H26_RS11485	COG3188	usher protein
A8H26_RS11490	COG3539	Fimbrial protein
A8H26_RS11495	COG3539	Fimbrial protein
A8H26_RS11500	COG3539	Fimbrial protein
A8H26_RS11505	COG2814	Major facilitator Superfamily
A8H26_RS11510	COG2850	peptidyl-arginine hydroxylation
A8H26_RS11535	COG4565	transcriptional regulatory protein
A8H26_RS11540	COG3290	protein histidine kinase activity
A8H26_RS11555	COG2801	Transposase and inactivated derivatives
A8H26_RS11575	COG1113	amino acid transport
A8H26_RS11580	COG0668	transmembrane transport
A8H26_RS11595	COG0778	Nitroreductase
A8H26_RS11600	COG2315	Protein conserved in bacteria
A8H26_RS11625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8H26_RS11635	COG0765	amino acid transport
A8H26_RS11640	COG0765	amino acid transport
A8H26_RS11660	COG4221	oxidoreductase activity
A8H26_RS11665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A8H26_RS11670	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A8H26_RS11670	COG0517	IMP dehydrogenase activity
A8H26_RS11675	COG1349	DNA-binding transcription factor activity
A8H26_RS11680	COG3395	kinase activity
A8H26_RS11685	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A8H26_RS11690	COG2610	gluconate transmembrane transporter activity
A8H26_RS11715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A8H26_RS11720	COG2977	Belongs to the P-Pant transferase superfamily
A8H26_RS11725	COG4771	TonB-dependent receptor
A8H26_RS11730	COG2382	esterase
A8H26_RS11735	COG3251	PFAM MbtH domain protein
A8H26_RS11740	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A8H26_RS11740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A8H26_RS11745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A8H26_RS11750	COG1120	ATPase activity
A8H26_RS11755	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8H26_RS11760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8H26_RS11770	COG4592	Periplasmic binding protein
A8H26_RS11775	COG1169	isochorismate synthase
A8H26_RS11780	COG1021	2,3-dihydroxybenzoate-AMP ligase
A8H26_RS11785	COG1535	isochorismatase
A8H26_RS11785	COG3433	isochorismatase activity
A8H26_RS11790	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS11795	COG2050	protein possibly involved in aromatic compounds catabolism
A8H26_RS11805	COG0700	Nucleoside recognition
A8H26_RS11810	COG3366	ferrous iron transmembrane transporter activity
A8H26_RS11815	COG1966	Carbon starvation protein
A8H26_RS11820	COG2879	small protein
A8H26_RS11825	COG1129	ABC transporter
A8H26_RS11830	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8H26_RS11860	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
A8H26_RS11865	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
A8H26_RS11870	COG0235	Class ii aldolase
A8H26_RS11875	COG0436	Aminotransferase
A8H26_RS11880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A8H26_RS11900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A8H26_RS11905	COG3719	Belongs to the RNase T2 family
A8H26_RS11910	COG3069	C4-dicarboxylate transmembrane transporter activity
A8H26_RS11930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8H26_RS11935	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8H26_RS11955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A8H26_RS11960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A8H26_RS11965	COG2233	PERMEase
A8H26_RS11975	COG0583	DNA-binding transcription factor activity
A8H26_RS11980	COG0321	lipoyl(octanoyl) transferase activity
A8H26_RS11985	COG2921	Belongs to the UPF0250 family
A8H26_RS11990	COG1686	Belongs to the peptidase S11 family
A8H26_RS11995	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A8H26_RS12000	COG0772	Belongs to the SEDS family
A8H26_RS12005	COG0768	penicillin binding
A8H26_RS12015	COG0799	negative regulation of ribosome biogenesis
A8H26_RS12025	COG1466	dna polymerase III delta subunit
A8H26_RS12040	COG2888	peptidyl-tyrosine sulfation
A8H26_RS12045	COG1126	abc transporter atp-binding protein
A8H26_RS12050	COG0765	amino acid transport
A8H26_RS12055	COG0765	amino acid transport
A8H26_RS12085	COG1702	phosphate starvation-inducible protein PhoH
A8H26_RS12095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8H26_RS12135	COG0367	asparagine synthase
A8H26_RS12140	COG0647	UMP catabolic process
A8H26_RS12145	COG1846	Transcriptional regulator
A8H26_RS12145	COG1940	carbohydrate kinase activity
A8H26_RS12150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A8H26_RS12160	COG2190	(PTS) system
A8H26_RS12160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8H26_RS12160	COG1263	PTS System
A8H26_RS12170	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS12200	COG1053	succinate dehydrogenase
A8H26_RS12205	COG0583	DNA-binding transcription factor activity
A8H26_RS12210	COG0735	belongs to the Fur family
A8H26_RS12215	COG0716	FMN binding
A8H26_RS12225	COG0596	Alpha beta hydrolase
A8H26_RS12230	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
A8H26_RS12235	COG0033	Phosphoglucomutase
A8H26_RS12240	COG0477	Major facilitator Superfamily
A8H26_RS12250	COG5642	Protein of unknown function (DUF2384)
A8H26_RS12255	COG5654	RES domain protein
A8H26_RS12265	COG2962	Rard protein
A8H26_RS12280	COG0531	amino acid
A8H26_RS12285	COG1982	Orn Lys Arg decarboxylase major
A8H26_RS12295	COG0745	RESPONSE REGULATOR receiver
A8H26_RS12300	COG2205	protein histidine kinase activity
A8H26_RS12310	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A8H26_RS12315	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
A8H26_RS12350	COG1120	ATPase activity
A8H26_RS12355	COG0500	methyltransferase
A8H26_RS12380	COG1012	belongs to the aldehyde dehydrogenase family
A8H26_RS12385	COG0583	DNA-binding transcription factor activity
A8H26_RS12390	COG2072	flavoprotein involved in K transport
A8H26_RS12405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A8H26_RS12420	COG3272	Protein of unknown function (DUF1722)
A8H26_RS12435	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A8H26_RS12440	COG1984	allophanate hydrolase subunit 2
A8H26_RS12460	COG2009	succinate dehydrogenase
A8H26_RS12465	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A8H26_RS12475	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A8H26_RS12480	COG0567	Dehydrogenase, E1 component
A8H26_RS12485	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8H26_RS12495	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A8H26_RS12500	COG1271	oxidase subunit
A8H26_RS12505	COG1294	oxidase, subunit
A8H26_RS12510	COG4890	Cyd operon protein YbgT
A8H26_RS12515	COG3790	cyd operon protein YbgE
A8H26_RS12520	COG0824	Thioesterase
A8H26_RS12525	COG0811	peptide transport
A8H26_RS12530	COG0848	biopolymer transport protein
A8H26_RS12535	COG3064	Membrane
A8H26_RS12545	COG2885	chlorophyll binding
A8H26_RS12550	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
A8H26_RS12585	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A8H26_RS12595	COG1230	cation diffusion facilitator family transporter
A8H26_RS12605	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A8H26_RS12620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8H26_RS12625	COG1120	ATPase activity
A8H26_RS12635	COG2017	converts alpha-aldose to the beta-anomer
A8H26_RS12645	COG1085	galactose-1-phosphate uridylyltransferase
A8H26_RS12650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A8H26_RS12655	COG1119	ATPase activity
A8H26_RS12660	COG2005	Transcriptional regulator
A8H26_RS12660	COG3585	molybdate ion transport
A8H26_RS12670	COG0725	ABC transporter, periplasmic molybdate-binding protein
A8H26_RS12675	COG4149	molybdate abc transporter
A8H26_RS12700	COG0561	phosphatase activity
A8H26_RS12720	COG1289	transmembrane transporter activity
A8H26_RS12725	COG1538	Outer membrane efflux protein
A8H26_RS12730	COG4677	pectinesterase activity
A8H26_RS12785	COG1881	PFAM PEBP family protein
A8H26_RS12805	COG2226	methyltransferase
A8H26_RS12825	COG3121	Chaperone
A8H26_RS12830	COG3188	usher protein
A8H26_RS12835	COG3539	Fimbrial protein
A8H26_RS12840	COG0642	Histidine kinase
A8H26_RS12865	COG0521	Mo-molybdopterin cofactor biosynthetic process
A8H26_RS12870	COG0315	cyclic pyranopterin monophosphate synthase activity
A8H26_RS12875	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A8H26_RS12880	COG0314	molybdopterin synthase activity
A8H26_RS12885	COG0670	Belongs to the BI1 family
A8H26_RS12890	COG0392	lysyltransferase activity
A8H26_RS12895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8H26_RS12900	COG3568	Endonuclease Exonuclease Phosphatase
A8H26_RS12910	COG0842	Transport permease protein
A8H26_RS12915	COG0842	Transport permease protein
A8H26_RS12920	COG1131	(ABC) transporter
A8H26_RS12925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8H26_RS12930	COG1309	transcriptional regulator
A8H26_RS12935	COG0513	Belongs to the DEAD box helicase family
A8H26_RS12955	COG3141	response to X-ray
A8H26_RS12960	COG1199	ATP-dependent helicase activity
A8H26_RS12965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A8H26_RS12980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A8H26_RS12990	COG0668	transmembrane transport
A8H26_RS12995	COG1126	abc transporter atp-binding protein
A8H26_RS13000	COG0765	amino acid transport
A8H26_RS13005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8H26_RS13015	COG0783	Belongs to the Dps family
A8H26_RS13025	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A8H26_RS13030	COG2194	sulfuric ester hydrolase activity
A8H26_RS13040	COG1321	iron dependent repressor
A8H26_RS13045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A8H26_RS13050	COG2723	6-phospho-beta-galactosidase activity
A8H26_RS13055	COG2188	Transcriptional regulator
A8H26_RS13060	COG1376	ErfK ybiS ycfS ynhG family protein
A8H26_RS13065	COG0488	(ABC) transporter
A8H26_RS13070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A8H26_RS13070	COG1648	precorrin-2 dehydrogenase activity
A8H26_RS13170	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
A8H26_RS13185	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A8H26_RS13195	COG2271	Major facilitator Superfamily
A8H26_RS13200	COG1609	Transcriptional regulator
A8H26_RS13205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8H26_RS13215	COG0561	phosphatase activity
A8H26_RS13220	COG1882	Formate acetyltransferase
A8H26_RS13225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8H26_RS13230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A8H26_RS13245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A8H26_RS13250	COG0303	'Molybdopterin
A8H26_RS13255	COG1446	asparaginase
A8H26_RS13265	COG0747	negative chemotaxis
A8H26_RS13300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A8H26_RS13300	COG1648	precorrin-2 dehydrogenase activity
A8H26_RS13305	COG0243	molybdopterin cofactor binding
A8H26_RS13310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A8H26_RS13310	COG2146	nitrite reductase [NAD(P)H] activity
A8H26_RS13315	COG1116	anion transmembrane transporter activity
A8H26_RS13320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8H26_RS13325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8H26_RS13330	COG3707	response regulator
A8H26_RS13335	COG0523	cobalamin synthesis protein
A8H26_RS13350	COG2133	pyrroloquinoline quinone binding
A8H26_RS13355	COG0625	glutathione transferase activity
A8H26_RS13360	COG1686	Belongs to the peptidase S11 family
A8H26_RS13365	COG1349	DNA-binding transcription factor activity
A8H26_RS13370	COG0671	phosphoesterase, PA-phosphatase related
A8H26_RS13375	COG2814	Major facilitator Superfamily
A8H26_RS13380	COG0561	phosphatase activity
A8H26_RS13385	COG0738	Major facilitator superfamily
A8H26_RS13390	COG1312	Catalyzes the dehydration of D-mannonate
A8H26_RS13410	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
A8H26_RS13425	COG2985	domain, Protein
A8H26_RS13425	COG0569	domain protein
A8H26_RS13440	COG0778	Nitroreductase
A8H26_RS13455	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A8H26_RS13460	COG3842	ATPase activity
A8H26_RS13465	COG1176	ABC-type spermidine putrescine transport system, permease component I
A8H26_RS13470	COG1177	transmembrane transport
A8H26_RS13480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A8H26_RS13505	COG0745	RESPONSE REGULATOR receiver
A8H26_RS13510	COG5002	protein histidine kinase activity
A8H26_RS13515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8H26_RS13520	COG4160	amino acid transport
A8H26_RS13525	COG4215	(ABC) transporter
A8H26_RS13530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8H26_RS13535	COG1126	abc transporter atp-binding protein
A8H26_RS13545	COG0393	Putative heavy-metal-binding
A8H26_RS13550	COG3023	N-Acetylmuramoyl-L-alanine amidase
A8H26_RS13555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8H26_RS13560	COG0702	epimerase
A8H26_RS13565	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
A8H26_RS13570	COG0028	Belongs to the TPP enzyme family
A8H26_RS13575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8H26_RS13585	COG2431	L-lysine efflux transmembrane transporter activity
A8H26_RS13595	COG3593	DNA synthesis involved in DNA repair
A8H26_RS13600	COG2990	Protein conserved in bacteria
A8H26_RS13605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8H26_RS13615	COG1278	Cold shock
A8H26_RS13625	COG0542	response to heat
A8H26_RS13645	COG1609	Transcriptional regulator
A8H26_RS13650	COG2271	Major facilitator Superfamily
A8H26_RS13660	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A8H26_RS13665	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A8H26_RS13670	COG4988	ABC transporter
A8H26_RS13675	COG0492	ferredoxin-NADP+ reductase activity
A8H26_RS13690	COG1674	ftsk spoiiie
A8H26_RS13690	COG1178	ABC-type Fe3 transport system permease component
A8H26_RS13700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A8H26_RS13715	COG0477	Major facilitator Superfamily
A8H26_RS13725	COG0243	molybdopterin cofactor binding
A8H26_RS13730	COG0437	4 iron, 4 sulfur cluster binding
A8H26_RS13735	COG3302	dmso reductase anchor subunit
A8H26_RS13740	COG0477	Major facilitator Superfamily
A8H26_RS13750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8H26_RS13755	COG1882	Formate acetyltransferase
A8H26_RS13760	COG2116	formate transmembrane transporter activity
A8H26_RS13765	COG1944	ATP diphosphatase activity
A8H26_RS13770	COG2323	membrane
A8H26_RS13775	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A8H26_RS13790	COG0539	negative regulation of cytoplasmic translation
A8H26_RS13800	COG0658	competence protein
A8H26_RS13800	COG2333	competence protein COMEC
A8H26_RS13815	COG3214	Protein conserved in bacteria
A8H26_RS13820	COG2835	tetraacyldisaccharide 4'-kinase activity
A8H26_RS13830	COG3173	Aminoglycoside phosphotransferase
A8H26_RS13835	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A8H26_RS13840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A8H26_RS13850	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
A8H26_RS13860	COG2989	Protein conserved in bacteria
A8H26_RS13865	COG3108	Peptidase M15
A8H26_RS13870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8H26_RS13875	COG1448	Aminotransferase
A8H26_RS13890	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A8H26_RS13895	COG0308	aminopeptidase N
A8H26_RS13905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8H26_RS13915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8H26_RS13920	COG0431	NADPH-dependent FMN reductase
A8H26_RS13935	COG3217	Mosc domain protein beta barrel domain protein
A8H26_RS13935	COG0633	Ferredoxin
A8H26_RS13945	COG0488	(ABC) transporter
A8H26_RS13950	COG2995	paraquat-inducible protein a
A8H26_RS13955	COG3008	intermembrane lipid transfer
A8H26_RS13955	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A8H26_RS13960	COG3009	Protein conserved in bacteria
A8H26_RS13965	COG3130	regulation of translation
A8H26_RS13975	COG1067	ATP-dependent peptidase activity
A8H26_RS13985	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A8H26_RS13985	COG2885	chlorophyll binding
A8H26_RS13995	COG3070	regulator of competence-specific genes
A8H26_RS14000	COG1289	transmembrane transporter activity
A8H26_RS14005	COG3304	Inner membrane component domain
A8H26_RS14010	COG0210	DNA helicase
A8H26_RS14020	COG1832	CoA-binding protein
A8H26_RS14030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A8H26_RS14045	COG0670	Belongs to the BI1 family
A8H26_RS14095	COG1396	sequence-specific DNA binding
A8H26_RS14170	COG1403	HNH endonuclease
A8H26_RS14180	COG4977	sequence-specific DNA binding
A8H26_RS14190	COG3772	lysozyme
A8H26_RS14215	COG4220	transposase activity
A8H26_RS14235	COG0616	signal peptide processing
A8H26_RS14285	COG1196	nuclear chromosome segregation
A8H26_RS14330	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A8H26_RS14335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A8H26_RS14355	COG4104	PAAR repeat-containing protein
A8H26_RS14380	COG0628	permease
A8H26_RS14395	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8H26_RS14400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8H26_RS14405	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8H26_RS14415	COG1138	Cytochrome C-type biogenesis protein
A8H26_RS14420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8H26_RS14425	COG3088	subunit of a heme lyase
A8H26_RS14425	COG4235	cytochrome complex assembly
A8H26_RS14430	COG4235	cytochrome complex assembly
A8H26_RS14430	COG3088	subunit of a heme lyase
A8H26_RS14460	COG2274	protein secretion by the type I secretion system
A8H26_RS14480	COG0789	Transcriptional regulator
A8H26_RS14485	COG2200	EAL domain
A8H26_RS14530	COG3729	General stress protein
A8H26_RS14540	COG2233	PERMEase
A8H26_RS14545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A8H26_RS14575	COG1309	transcriptional regulator
A8H26_RS14585	COG0506	proline dehydrogenase activity
A8H26_RS14585	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A8H26_RS14585	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A8H26_RS14590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A8H26_RS14600	COG2822	iron ion transport
A8H26_RS14610	COG1702	phosphate starvation-inducible protein PhoH
A8H26_RS14615	COG1902	pentaerythritol trinitrate reductase activity
A8H26_RS14675	COG3381	protein complex oligomerization
A8H26_RS14685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8H26_RS14705	COG5645	(Lipo)protein
A8H26_RS14715	COG2814	Major facilitator Superfamily
A8H26_RS14720	COG1560	Kdo2-lipid A biosynthetic process
A8H26_RS14755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8H26_RS14770	COG0728	peptidoglycan biosynthetic process
A8H26_RS14810	COG1558	bacterial-type flagellum-dependent cell motility
A8H26_RS14820	COG1749	Flagellar hook protein flgE
A8H26_RS14850	COG1256	bacterial-type flagellum assembly
A8H26_RS14855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A8H26_RS14860	COG1530	ribonuclease E activity
A8H26_RS14885	COG1399	metal-binding, possibly nucleic acid-binding protein
A8H26_RS14905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A8H26_RS14910	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS14920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A8H26_RS14925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A8H26_RS14930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A8H26_RS14940	COG0470	DNA polymerase III
A8H26_RS14945	COG0084	hydrolase, TatD family'
A8H26_RS14950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8H26_RS14950	COG1263	PTS System
A8H26_RS14955	COG0537	adenosine 5'-monophosphoramidase activity
A8H26_RS14960	COG5633	Lipoprotein
A8H26_RS14965	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
A8H26_RS14985	COG1252	NADH dehydrogenase
A8H26_RS14990	COG3134	Outer membrane lipoprotein
A8H26_RS14995	COG0840	transmembrane signaling receptor activity
A8H26_RS15000	COG1309	transcriptional regulator
A8H26_RS15010	COG1388	LysM domain
A8H26_RS15010	COG1376	ErfK ybiS ycfS ynhG family protein
A8H26_RS15015	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A8H26_RS15020	COG4591	ABC-type transport system involved in lipoprotein release permease component
A8H26_RS15025	COG1136	(ABC) transporter
A8H26_RS15030	COG4591	ABC-type transport system involved in lipoprotein release permease component
A8H26_RS15060	COG0531	amino acid
A8H26_RS15065	COG1177	transmembrane transport
A8H26_RS15085	COG2850	peptidyl-arginine hydroxylation
A8H26_RS15090	COG2205	protein histidine kinase activity
A8H26_RS15095	COG0745	RESPONSE REGULATOR receiver
A8H26_RS15105	COG1560	Kdo2-lipid A biosynthetic process
A8H26_RS15110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A8H26_RS15145	COG0538	isocitrate dehydrogenase activity
A8H26_RS15155	COG2719	SpoVR family
A8H26_RS15170	COG2186	Transcriptional regulator
A8H26_RS15200	COG3706	GGDEF domain
A8H26_RS15205	COG3042	response to heat
A8H26_RS15210	COG3189	MarR family transcriptional regulator
A8H26_RS15215	COG0504	CTP synthase activity
A8H26_RS15220	COG2807	transmembrane transport
A8H26_RS15225	COG2207	Transcriptional regulator
A8H26_RS15230	COG2707	UPF0756 membrane protein
A8H26_RS15235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A8H26_RS15240	COG2718	Belongs to the UPF0229 family
A8H26_RS15245	COG2766	serine protein kinase
A8H26_RS15250	COG3713	MltA-interacting MipA family protein
A8H26_RS15255	COG0656	L-ascorbic acid biosynthetic process
A8H26_RS15265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A8H26_RS15275	COG3139	Protein of unknown function (DUF1315)
A8H26_RS15290	COG1335	isochorismatase
A8H26_RS15295	COG0252	asparaginase activity
A8H26_RS15300	COG0616	signal peptide processing
A8H26_RS15305	COG0778	Nitroreductase
A8H26_RS15320	COG0709	Synthesizes selenophosphate from selenide and ATP
A8H26_RS15325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A8H26_RS15340	COG0494	nUDIX hydrolase
A8H26_RS15345	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8H26_RS15350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A8H26_RS15360	COG2897	thiosulfate sulfurtransferase activity
A8H26_RS15365	COG4136	ATPase activity
A8H26_RS15370	COG4135	transport system, permease component
A8H26_RS15375	COG4134	Bacterial extracellular solute-binding protein
A8H26_RS15385	COG0708	Exodeoxyribonuclease III
A8H26_RS15400	COG1012	belongs to the aldehyde dehydrogenase family
A8H26_RS15415	COG3678	ATP-independent chaperone mediated protein folding
A8H26_RS15420	COG0322	excinuclease ABC activity
A8H26_RS15430	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8H26_RS15435	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8H26_RS15440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8H26_RS15445	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8H26_RS15450	COG2169	Transcriptional regulator
A8H26_RS15450	COG1917	Cupin 2, conserved barrel domain protein
A8H26_RS15455	COG1486	melibiose metabolic process
A8H26_RS15465	COG0753	catalase activity
A8H26_RS15475	COG1823	symporter activity
A8H26_RS15480	COG1988	membrane-bound metal-dependent
A8H26_RS15485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8H26_RS15495	COG1607	acyl-coa hydrolase
A8H26_RS15510	COG0727	PFAM Uncharacterised protein family (UPF0153)
A8H26_RS15515	COG3047	cAMP biosynthetic process
A8H26_RS15540	COG0512	Glutamine amidotransferase of anthranilate synthase
A8H26_RS15540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A8H26_RS15545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A8H26_RS15555	COG0009	L-threonylcarbamoyladenylate synthase
A8H26_RS15560	COG1187	pseudouridine synthase activity
A8H26_RS15565	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A8H26_RS15570	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS15575	COG0616	signal peptide processing
A8H26_RS15595	COG1442	glycosyl transferase family 8
A8H26_RS15610	COG0671	phosphoesterase, PA-phosphatase related
A8H26_RS15615	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
A8H26_RS15620	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
A8H26_RS15635	COG0023	Translation Initiation Factor
A8H26_RS15645	COG1349	DNA-binding transcription factor activity
A8H26_RS15660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8H26_RS15660	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8H26_RS15665	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A8H26_RS15680	COG4171	peptide transport system, permease
A8H26_RS15705	COG1473	amidohydrolase
A8H26_RS15715	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A8H26_RS15720	COG1842	Phage shock protein A
A8H26_RS15730	COG1983	PspC domain protein
A8H26_RS15740	COG3106	COG3106 Predicted ATPase
A8H26_RS15755	COG3180	Ammonia monooxygenase
A8H26_RS15760	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A8H26_RS15765	COG4948	Mandelate Racemase Muconate Lactonizing
A8H26_RS15770	COG2866	Carboxypeptidase
A8H26_RS15775	COG4166	transmembrane transport
A8H26_RS15790	COG0840	transmembrane signaling receptor activity
A8H26_RS15805	COG0582	viral genome integration into host DNA
A8H26_RS15845	COG3477	response to acidic pH
A8H26_RS15870	COG3023	N-Acetylmuramoyl-L-alanine amidase
A8H26_RS15880	COG0674	pyruvate-flavodoxin oxidoreductase activity
A8H26_RS15880	COG1013	pyruvate-flavodoxin oxidoreductase activity
A8H26_RS15880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8H26_RS15880	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A8H26_RS15885	COG3042	response to heat
A8H26_RS15890	COG3187	Heat shock protein
A8H26_RS15895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A8H26_RS15900	COG2911	Protein conserved in bacteria
A8H26_RS15910	COG3784	Protein of unknown function (DUF1318)
A8H26_RS15925	COG2207	Transcriptional regulator
A8H26_RS15930	COG1012	belongs to the aldehyde dehydrogenase family
A8H26_RS15940	COG2199	diguanylate cyclase activity
A8H26_RS15950	COG2610	gluconate transmembrane transporter activity
A8H26_RS15960	COG1012	belongs to the aldehyde dehydrogenase family
A8H26_RS15960	COG2030	dehydratase
A8H26_RS15965	COG3396	Phenylacetate-CoA oxygenase
A8H26_RS15970	COG3460	Phenylacetate-CoA oxygenase
A8H26_RS15975	COG3396	Phenylacetate-CoA oxygenase
A8H26_RS15980	COG2151	metal-sulfur cluster biosynthetic enzyme
A8H26_RS15985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8H26_RS15990	COG1024	Enoyl-CoA hydratase
A8H26_RS15995	COG1024	Enoyl-CoA hydratase
A8H26_RS16000	COG1250	3-hydroxyacyl-CoA dehydrogenase
A8H26_RS16005	COG2050	protein possibly involved in aromatic compounds catabolism
A8H26_RS16010	COG0183	Belongs to the thiolase family
A8H26_RS16015	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
A8H26_RS16020	COG3327	negative regulation of DNA-templated transcription, initiation
A8H26_RS16025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A8H26_RS16030	COG0791	NLP P60 protein
A8H26_RS16040	COG1643	Atp-dependent helicase
A8H26_RS16045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A8H26_RS16090	COG0277	FAD linked oxidase domain protein
A8H26_RS16095	COG4122	O-methyltransferase activity
A8H26_RS16100	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A8H26_RS16110	COG3038	cytochrome b561
A8H26_RS16120	COG0583	DNA-binding transcription factor activity
A8H26_RS16130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A8H26_RS16130	COG2169	Transcriptional regulator
A8H26_RS16145	COG3485	protocatechuate 3,4-dioxygenase
A8H26_RS16150	COG3485	protocatechuate 3,4-dioxygenase
A8H26_RS16155	COG5383	Protein conserved in bacteria
A8H26_RS16170	COG0583	DNA-binding transcription factor activity
A8H26_RS16180	COG0436	Aminotransferase
A8H26_RS16200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8H26_RS16205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A8H26_RS16210	COG1275	C4-dicarboxylate transporter malic acid transport protein
A8H26_RS16215	COG0500	methyltransferase
A8H26_RS16220	COG2195	Cleaves the N-terminal amino acid of tripeptides
A8H26_RS16225	COG0747	negative chemotaxis
A8H26_RS16245	COG2353	YceI-like domain
A8H26_RS16250	COG3135	benzoate transporter
A8H26_RS16255	COG1396	sequence-specific DNA binding
A8H26_RS16260	COG0826	peptidase U32
A8H26_RS16265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8H26_RS16270	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A8H26_RS16275	COG3842	ATPase activity
A8H26_RS16280	COG1176	ABC-type spermidine putrescine transport system, permease component I
A8H26_RS16285	COG1177	transmembrane transport
A8H26_RS16290	COG1012	belongs to the aldehyde dehydrogenase family
A8H26_RS16295	COG2261	transglycosylase associated protein
A8H26_RS16325	COG1012	belongs to the aldehyde dehydrogenase family
A8H26_RS16345	COG0747	negative chemotaxis
A8H26_RS16360	COG1414	Transcriptional regulator
A8H26_RS16370	COG1454	alcohol dehydrogenase
A8H26_RS16375	COG3238	Protein conserved in bacteria
A8H26_RS16380	COG1247	-acetyltransferase
A8H26_RS16390	COG1396	sequence-specific DNA binding
A8H26_RS16395	COG2130	NADP-dependent
A8H26_RS16400	COG1802	Transcriptional regulator
A8H26_RS16405	COG4772	TonB-dependent receptor
A8H26_RS16410	COG3391	amine dehydrogenase activity
A8H26_RS16420	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
A8H26_RS16425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A8H26_RS16430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A8H26_RS16430	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A8H26_RS16435	COG0583	DNA-binding transcription factor activity
A8H26_RS16440	COG1741	Belongs to the pirin family
A8H26_RS16445	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A8H26_RS16450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8H26_RS16455	COG1473	amidohydrolase
A8H26_RS16460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8H26_RS16475	COG0765	amino acid transport
A8H26_RS16480	COG1126	abc transporter atp-binding protein
A8H26_RS16540	COG1942	4-Oxalocrotonate Tautomerase
A8H26_RS16550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8H26_RS16560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8H26_RS16575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A8H26_RS16580	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A8H26_RS16585	COG2181	nitrate reductase activity
A8H26_RS16590	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A8H26_RS16595	COG1140	nitrate reductase beta subunit
A8H26_RS16605	COG2223	nitrite transmembrane transporter activity
A8H26_RS16625	COG3383	formate dehydrogenase (NAD+) activity
A8H26_RS16625	COG0243	molybdopterin cofactor binding
A8H26_RS16630	COG0243	molybdopterin cofactor binding
A8H26_RS16630	COG3383	formate dehydrogenase (NAD+) activity
A8H26_RS16635	COG0437	4 iron, 4 sulfur cluster binding
A8H26_RS16640	COG2864	formate dehydrogenase
A8H26_RS16645	COG2814	Major facilitator Superfamily
A8H26_RS16650	COG1064	alcohol dehydrogenase
A8H26_RS16655	COG0488	(ABC) transporter
A8H26_RS16665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8H26_RS16665	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A8H26_RS16670	COG0726	polysaccharide deacetylase
A8H26_RS16675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A8H26_RS16685	COG2076	Multidrug Resistance protein
A8H26_RS16690	COG0281	malic enzyme
A8H26_RS16700	COG1764	response to oxidative stress
A8H26_RS16720	COG2814	Major facilitator Superfamily
A8H26_RS16735	COG1649	PFAM Uncharacterised BCR, COG1649
A8H26_RS16740	COG2851	Citrate transporter
A8H26_RS16750	COG0583	DNA-binding transcription factor activity
A8H26_RS16755	COG0477	Major facilitator Superfamily
A8H26_RS16755	COG2814	Major facilitator Superfamily
A8H26_RS16760	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A8H26_RS16770	COG2259	Doxx family
A8H26_RS16825	COG0596	Alpha beta hydrolase
A8H26_RS16840	COG5285	phytanoyl-CoA dioxygenase
A8H26_RS16845	COG1126	abc transporter atp-binding protein
A8H26_RS16855	COG2308	Evidence 4 Homologs of previously reported genes of
A8H26_RS16875	COG1473	amidohydrolase
A8H26_RS16905	COG0477	Major facilitator Superfamily
A8H26_RS16910	COG0640	Transcriptional regulator
A8H26_RS16955	COG2011	ABC-type metal ion transport system permease component
A8H26_RS16970	COG0697	spore germination
A8H26_RS16975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8H26_RS16980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A8H26_RS17000	COG3781	membrane
A8H26_RS17015	COG5002	protein histidine kinase activity
A8H26_RS17015	COG5001	Diguanylate cyclase
A8H26_RS17015	COG3447	MASE1 domain protein
A8H26_RS17020	COG2199	diguanylate cyclase activity
A8H26_RS17040	COG2985	domain, Protein
A8H26_RS17045	COG1012	belongs to the aldehyde dehydrogenase family
A8H26_RS17050	COG0583	DNA-binding transcription factor activity
A8H26_RS17115	COG2814	Major facilitator Superfamily
A8H26_RS17120	COG3443	Belongs to the bacterial solute-binding protein 9 family
A8H26_RS17130	COG1129	ABC transporter
A8H26_RS17150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A8H26_RS17155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A8H26_RS17160	COG2271	Major facilitator Superfamily
A8H26_RS17170	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A8H26_RS17180	COG4977	sequence-specific DNA binding
A8H26_RS17185	COG0339	signal peptide processing
A8H26_RS17210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A8H26_RS17220	COG0402	S-adenosylhomocysteine deaminase activity
A8H26_RS17225	COG4221	oxidoreductase activity
A8H26_RS17230	COG1802	Transcriptional regulator
A8H26_RS17265	COG3622	Belongs to the hyi family
A8H26_RS17270	COG0477	Major facilitator Superfamily
A8H26_RS17295	COG0431	NADPH-dependent FMN reductase
A8H26_RS17345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8H26_RS17360	COG0246	Mannitol dehydrogenase
A8H26_RS17365	COG0477	Major facilitator Superfamily
A8H26_RS17370	COG1063	alcohol dehydrogenase
A8H26_RS17375	COG2271	Major facilitator Superfamily
A8H26_RS17380	COG1742	UPF0060 membrane protein
A8H26_RS17395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8H26_RS17410	COG0243	molybdopterin cofactor binding
A8H26_RS17415	COG3381	protein complex oligomerization
A8H26_RS17445	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A8H26_RS17450	COG1940	carbohydrate kinase activity
A8H26_RS17455	COG0583	DNA-binding transcription factor activity
A8H26_RS17460	COG2814	Major facilitator Superfamily
A8H26_RS17465	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A8H26_RS17495	COG3591	Belongs to the peptidase S1B family
A8H26_RS17500	COG3300	MHYT domain
A8H26_RS17500	COG5001	Diguanylate cyclase
A8H26_RS17555	COG0679	Auxin Efflux Carrier
A8H26_RS17565	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A8H26_RS17590	COG0425	Belongs to the sulfur carrier protein TusA family
A8H26_RS17620	COG3485	protocatechuate 3,4-dioxygenase
A8H26_RS17625	COG1414	Transcriptional regulator
A8H26_RS17655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A8H26_RS17685	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
A8H26_RS17690	COG1051	belongs to the nudix hydrolase family
A8H26_RS17695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8H26_RS17700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A8H26_RS17710	COG0183	Belongs to the thiolase family
A8H26_RS17715	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A8H26_RS17725	COG1414	Transcriptional regulator
A8H26_RS17730	COG2840	Smr protein MutS2
A8H26_RS17735	COG0583	DNA-binding transcription factor activity
A8H26_RS17745	COG1473	amidohydrolase
A8H26_RS17750	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A8H26_RS17755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A8H26_RS17760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A8H26_RS17780	COG0589	response to stress
A8H26_RS17795	COG0840	transmembrane signaling receptor activity
A8H26_RS17825	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A8H26_RS17830	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A8H26_RS17840	COG0531	amino acid
A8H26_RS17845	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS17850	COG3136	membrane protein required for alginate biosynthesis
A8H26_RS17855	COG0745	RESPONSE REGULATOR receiver
A8H26_RS17860	COG2205	protein histidine kinase activity
A8H26_RS17875	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A8H26_RS17875	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A8H26_RS17885	COG5339	Protein conserved in bacteria
A8H26_RS17905	COG3328	transposase activity
A8H26_RS18030	COG3039	Transposase
A8H26_RS18035	COG4193	domain, Protein
A8H26_RS18065	COG2885	chlorophyll binding
A8H26_RS18090	COG1609	Transcriptional regulator
A8H26_RS18095	COG1263	PTS System
A8H26_RS18095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8H26_RS18100	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A8H26_RS18115	COG0673	inositol 2-dehydrogenase activity
A8H26_RS18155	COG4659	FMN binding
A8H26_RS18165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A8H26_RS18175	COG0625	glutathione transferase activity
A8H26_RS18190	COG3895	Periplasmic Protein
A8H26_RS18215	COG1566	PFAM secretion protein HlyD family protein
A8H26_RS18225	COG2032	superoxide dismutase activity
A8H26_RS18230	COG4989	oxidoreductase activity
A8H26_RS18235	COG3313	Fe-S protein
A8H26_RS18240	COG1309	transcriptional regulator
A8H26_RS18245	COG1902	pentaerythritol trinitrate reductase activity
A8H26_RS18250	COG0346	lactoylglutathione lyase activity
A8H26_RS18260	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A8H26_RS18265	COG0791	NLP P60 protein
A8H26_RS18275	COG2814	Major facilitator Superfamily
A8H26_RS18290	COG0583	DNA-binding transcription factor activity
A8H26_RS18295	COG2814	Major facilitator Superfamily
A8H26_RS18300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A8H26_RS18305	COG0307	riboflavin synthase, alpha
A8H26_RS18315	COG0531	amino acid
A8H26_RS18345	COG0583	DNA-binding transcription factor activity
A8H26_RS18350	COG0402	S-adenosylhomocysteine deaminase activity
A8H26_RS18375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8H26_RS18410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8H26_RS18415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8H26_RS18420	COG1120	ATPase activity
A8H26_RS18425	COG4774	siderophore transport
A8H26_RS18430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8H26_RS18435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8H26_RS18440	COG1120	ATPase activity
A8H26_RS18475	COG1376	ErfK ybiS ycfS ynhG family protein
A8H26_RS18490	COG0719	Fe-S assembly protein
A8H26_RS18495	COG0396	ATPase activity
A8H26_RS18500	COG0719	Fe-S assembly protein
A8H26_RS18505	COG0316	Belongs to the HesB IscA family
A8H26_RS18510	COG1560	Kdo2-lipid A biosynthetic process
A8H26_RS18515	COG2050	protein possibly involved in aromatic compounds catabolism
A8H26_RS18520	COG0277	FAD linked oxidase domain protein
A8H26_RS18520	COG0247	lactate metabolic process
A8H26_RS18525	COG0628	permease
A8H26_RS18535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A8H26_RS18535	COG0574	Belongs to the PEP-utilizing enzyme family
A8H26_RS18545	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A8H26_RS18550	COG3720	iron ion transport
A8H26_RS18555	COG4558	Periplasmic binding protein
A8H26_RS18560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8H26_RS18590	COG0791	NLP P60 protein
A8H26_RS18600	COG0386	Belongs to the glutathione peroxidase family
A8H26_RS18630	COG0776	regulation of translation
A8H26_RS18635	COG0072	phenylalanine-tRNA ligase activity
A8H26_RS18635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A8H26_RS18675	COG3137	Salt-induced outer membrane protein
A8H26_RS18685	COG3001	Fructosamine kinase
A8H26_RS18710	COG2350	Protein conserved in bacteria
A8H26_RS18725	COG4608	Belongs to the ABC transporter superfamily
A8H26_RS18730	COG0444	Belongs to the ABC transporter superfamily
A8H26_RS18735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8H26_RS18740	COG0601	transmembrane transport
A8H26_RS18745	COG4166	transmembrane transport
A8H26_RS18750	COG2095	MarC family integral membrane protein
A8H26_RS18755	COG1012	belongs to the aldehyde dehydrogenase family
A8H26_RS18755	COG1454	alcohol dehydrogenase
A8H26_RS18760	COG1435	thymidine kinase activity
A8H26_RS18770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A8H26_RS18775	COG0745	RESPONSE REGULATOR receiver
A8H26_RS18780	COG1752	Esterase of the alpha-beta hydrolase superfamily
A8H26_RS18790	COG0788	formyltetrahydrofolate deformylase activity
A8H26_RS18820	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A8H26_RS18825	COG2181	nitrate reductase activity
A8H26_RS18830	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A8H26_RS18835	COG1140	nitrate reductase beta subunit
A8H26_RS18845	COG2223	nitrite transmembrane transporter activity
A8H26_RS18850	COG3850	Histidine kinase
A8H26_RS18855	COG2197	response regulator
A8H26_RS18860	COG4932	domain protein
A8H26_RS18870	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A8H26_RS18895	COG2274	protein secretion by the type I secretion system
A8H26_RS18920	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
A8H26_RS18925	COG4572	Cation transport regulator
A8H26_RS18930	COG0387	Pfam Sodium calcium exchanger
A8H26_RS18945	COG2890	protein-(glutamine-N5) methyltransferase activity
A8H26_RS18980	COG0659	secondary active sulfate transmembrane transporter activity
A8H26_RS18995	COG0012	GTP binding
A8H26_RS19005	COG0493	'glutamate synthase
A8H26_RS19010	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A8H26_RS19010	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A8H26_RS19010	COG1013	pyruvate-flavodoxin oxidoreductase activity
A8H26_RS19010	COG0674	pyruvate-flavodoxin oxidoreductase activity
A8H26_RS19040	COG4772	TonB-dependent receptor
A8H26_RS19060	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A8H26_RS19070	COG0513	Belongs to the DEAD box helicase family
A8H26_RS19085	COG0583	DNA-binding transcription factor activity
A8H26_RS19095	COG4774	siderophore transport
A8H26_RS19100	COG0741	lytic transglycosylase activity
A8H26_RS19105	COG1619	proteins homologs of microcin C7 resistance protein MccF
A8H26_RS19140	COG3121	Chaperone
A8H26_RS19145	COG2983	Belongs to the UPF0260 family
A8H26_RS19150	COG0179	Fumarylacetoacetate (FAA) hydrolase
A8H26_RS19165	COG2894	cell division
A8H26_RS19175	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A8H26_RS19180	COG0318	PFAM AMP-dependent synthetase and ligase
A8H26_RS19185	COG3065	identical protein binding
A8H26_RS19195	COG1199	ATP-dependent helicase activity
A8H26_RS19200	COG0251	oxidation-reduction process
A8H26_RS19220	COG1760	l-serine dehydratase
A8H26_RS19225	COG2200	EAL domain
A8H26_RS19235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8H26_RS19235	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8H26_RS19240	COG3715	PTS system
A8H26_RS19245	COG3716	PTS system mannose fructose sorbose family IID component
A8H26_RS19255	COG1971	Probably functions as a manganese efflux pump
A8H26_RS19260	COG2226	methyltransferase
A8H26_RS19265	COG0768	penicillin binding
A8H26_RS19300	COG1414	Transcriptional regulator
A8H26_RS19320	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
A8H26_RS19325	COG1956	GAF domain-containing protein
A8H26_RS19330	COG2995	paraquat-inducible protein a
A8H26_RS19335	COG3008	intermembrane lipid transfer
A8H26_RS19365	COG1276	copper resistance
A8H26_RS19370	COG2372	response to copper ion
A8H26_RS19380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A8H26_RS19385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8H26_RS19390	COG1770	oligopeptidase
A8H26_RS19395	COG2979	Protein of unknown function (DUF533)
A8H26_RS19405	COG0800	Aldolase
A8H26_RS19410	COG0129	dihydroxy-acid dehydratase activity
A8H26_RS19415	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A8H26_RS19420	COG1737	Transcriptional regulator
A8H26_RS19425	COG0469	pyruvate kinase activity
A8H26_RS19430	COG1560	Kdo2-lipid A biosynthetic process
A8H26_RS19435	COG0739	heme binding
A8H26_RS19440	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
A8H26_RS19450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8H26_RS19455	COG2255	four-way junction helicase activity
A8H26_RS19475	COG0494	nUDIX hydrolase
A8H26_RS19485	COG1335	isochorismatase
A8H26_RS19490	COG1801	Protein of unknown function DUF72
A8H26_RS19495	COG3788	relative of glutathione S-transferase, MAPEG superfamily
A8H26_RS19505	COG0500	methyltransferase
A8H26_RS19515	COG3102	Protein conserved in bacteria
A8H26_RS19535	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A8H26_RS19550	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A8H26_RS19560	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS19565	COG2610	gluconate transmembrane transporter activity
A8H26_RS19580	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A8H26_RS19585	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A8H26_RS19590	COG0583	DNA-binding transcription factor activity
A8H26_RS19595	COG0232	Belongs to the dGTPase family. Type 2 subfamily
A8H26_RS19610	COG0745	RESPONSE REGULATOR receiver
A8H26_RS19625	COG0840	transmembrane signaling receptor activity
A8H26_RS19635	COG0835	chemotaxis
A8H26_RS19680	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8H26_RS19690	COG1879	ABC-type sugar transport system periplasmic component
A8H26_RS19695	COG1528	Iron-storage protein
A8H26_RS19705	COG0477	Major facilitator Superfamily
A8H26_RS19720	COG1528	Iron-storage protein
A8H26_RS19725	COG0814	amino acid
A8H26_RS19730	COG3012	SEC-C Motif Domain Protein
A8H26_RS19730	COG3318	Belongs to the UPF0149 family
A8H26_RS19775	COG2197	response regulator
A8H26_RS19785	COG2197	response regulator
A8H26_RS19790	COG1126	abc transporter atp-binding protein
A8H26_RS19795	COG0765	amino acid transport
A8H26_RS19805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8H26_RS19820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A8H26_RS19830	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A8H26_RS19835	COG1516	flagellar protein fliS
A8H26_RS19845	COG0366	Alpha amylase catalytic
A8H26_RS19855	COG0840	transmembrane signaling receptor activity
A8H26_RS19880	COG1733	regulation of RNA biosynthetic process
A8H26_RS19900	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A8H26_RS19910	COG1157	protein secretion by the type III secretion system
A8H26_RS19920	COG3144	bacterial-type flagellum assembly
A8H26_RS19925	COG1580	Controls the rotational direction of flagella during chemotaxis
A8H26_RS19930	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A8H26_RS19935	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A8H26_RS19945	COG1338	Plays a role in the flagellum-specific transport system
A8H26_RS19970	COG2814	Major facilitator Superfamily
A8H26_RS19980	COG1053	succinate dehydrogenase
A8H26_RS19990	COG1053	succinate dehydrogenase
A8H26_RS19995	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A8H26_RS20000	COG1414	Transcriptional regulator
A8H26_RS20010	COG5475	Uncharacterized small protein (DUF2158)
A8H26_RS20015	COG2354	Protein conserved in bacteria
A8H26_RS20020	COG3727	T/G mismatch-specific endonuclease activity
A8H26_RS20025	COG0270	DNA (cytosine-5-)-methyltransferase activity
A8H26_RS20045	COG3829	transcription factor binding
A8H26_RS20050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A8H26_RS20055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A8H26_RS20060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A8H26_RS20070	COG0549	Belongs to the carbamate kinase family
A8H26_RS20080	COG2233	PERMEase
A8H26_RS20085	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
A8H26_RS20085	COG3608	succinylglutamate desuccinylase aspartoacylase
A8H26_RS20090	COG0493	'glutamate synthase
A8H26_RS20090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8H26_RS20095	COG0402	S-adenosylhomocysteine deaminase activity
A8H26_RS20100	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8H26_RS20105	COG0493	'glutamate synthase
A8H26_RS20105	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8H26_RS20110	COG2233	PERMEase
A8H26_RS20140	COG2068	MobA-Related Protein
A8H26_RS20155	COG2040	homocysteine
A8H26_RS20160	COG0833	amino acid
A8H26_RS20170	COG4829	muconolactone delta-isomerase
A8H26_RS20175	COG4948	Mandelate Racemase Muconate Lactonizing
A8H26_RS20180	COG0583	DNA-binding transcription factor activity
A8H26_RS20200	COG3228	Belongs to the MtfA family
A8H26_RS20230	COG0583	DNA-binding transcription factor activity
A8H26_RS20250	COG0028	Belongs to the TPP enzyme family
A8H26_RS20255	COG0667	Aldo Keto reductase
A8H26_RS20260	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A8H26_RS20265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8H26_RS20285	COG0243	molybdopterin cofactor binding
A8H26_RS20290	COG0583	DNA-binding transcription factor activity
A8H26_RS20295	COG1376	ErfK ybiS ycfS ynhG family protein
A8H26_RS20325	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A8H26_RS20335	COG0583	DNA-binding transcription factor activity
A8H26_RS20340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A8H26_RS20350	COG1301	dicarboxylic acid transport
A8H26_RS20355	COG0471	metal ion transport
A8H26_RS20380	COG0640	Transcriptional regulator
A8H26_RS20390	COG2301	Belongs to the HpcH HpaI aldolase family
A8H26_RS20405	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
A8H26_RS20410	COG1960	acyl-CoA dehydrogenase activity
A8H26_RS20420	COG0477	Major facilitator Superfamily
A8H26_RS20430	COG0583	DNA-binding transcription factor activity
A8H26_RS20435	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
A8H26_RS20435	COG0028	Belongs to the TPP enzyme family
A8H26_RS20445	COG0583	DNA-binding transcription factor activity
A8H26_RS20465	COG1823	symporter activity
A8H26_RS20490	COG1132	(ABC) transporter
A8H26_RS20490	COG2375	cellular response to nickel ion
A8H26_RS20495	COG3433	isochorismatase activity
A8H26_RS20495	COG2226	methyltransferase
A8H26_RS20495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A8H26_RS20520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A8H26_RS20520	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A8H26_RS20525	COG0477	Major facilitator Superfamily
A8H26_RS20530	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A8H26_RS20545	COG0747	negative chemotaxis
A8H26_RS20550	COG1021	2,3-dihydroxybenzoate-AMP ligase
A8H26_RS20565	COG0523	cobalamin synthesis protein
A8H26_RS20575	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A8H26_RS20585	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
A8H26_RS20600	COG0531	amino acid
A8H26_RS20605	COG0174	glutamine synthetase
A8H26_RS20610	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A8H26_RS20615	COG1917	Cupin 2, conserved barrel domain protein
A8H26_RS20615	COG1396	sequence-specific DNA binding
A8H26_RS20620	COG1012	belongs to the aldehyde dehydrogenase family
A8H26_RS20625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A8H26_RS20630	COG0534	Mate efflux family protein
A8H26_RS20640	COG0582	viral genome integration into host DNA
A8H26_RS20645	COG2207	Transcriptional regulator
A8H26_RS20650	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A8H26_RS20655	COG1845	cytochrome c oxidase, subunit III
A8H26_RS20660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A8H26_RS20665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A8H26_RS20670	COG2814	Major facilitator Superfamily
A8H26_RS20675	COG1566	PFAM secretion protein HlyD family protein
A8H26_RS20705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A8H26_RS20725	COG3451	type IV secretory pathway VirB4
A8H26_RS20745	COG3736	Type IV secretory pathway, component VirB8
A8H26_RS20750	COG3504	Conjugal transfer protein
A8H26_RS20755	COG2948	multi-organism process
A8H26_RS20785	COG4227	nucleotidyltransferase activity
A8H26_RS20830	COG3621	Patatin-like phospholipase
A8H26_RS20860	COG2084	Dehydrogenase
A8H26_RS20870	COG0583	DNA-binding transcription factor activity
A8H26_RS20885	COG0251	oxidation-reduction process
A8H26_RS20890	COG0477	Major facilitator Superfamily
A8H26_RS20900	COG1289	transmembrane transporter activity
A8H26_RS20915	COG1461	Dihydroxyacetone kinase
A8H26_RS20920	COG2376	Dihydroxyacetone kinase
A8H26_RS20990	COG3121	Chaperone
A8H26_RS20995	COG3188	usher protein
A8H26_RS21005	COG2925	Exonuclease
A8H26_RS21015	COG0531	amino acid
A8H26_RS21025	COG0583	DNA-binding transcription factor activity
A8H26_RS21030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8H26_RS21050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A8H26_RS21055	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A8H26_RS21055	COG0131	Imidazoleglycerol-phosphate dehydratase
A8H26_RS21060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A8H26_RS21095	COG0438	transferase activity, transferring glycosyl groups
A8H26_RS21150	COG0562	UDP-galactopyranose mutase
A8H26_RS21160	COG5039	Polysaccharide pyruvyl transferase
A8H26_RS21185	COG0438	transferase activity, transferring glycosyl groups
A8H26_RS21195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A8H26_RS21235	COG1253	flavin adenine dinucleotide binding
A8H26_RS21240	COG2982	Protein involved in outer membrane biogenesis
A8H26_RS21260	COG5002	protein histidine kinase activity
A8H26_RS21260	COG3447	MASE1 domain protein
A8H26_RS21260	COG5001	Diguanylate cyclase
A8H26_RS21265	COG2814	Major facilitator Superfamily
A8H26_RS21270	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A8H26_RS21280	COG0443	Heat shock 70 kDa protein
A8H26_RS21310	COG2205	protein histidine kinase activity
A8H26_RS21315	COG0745	RESPONSE REGULATOR receiver
A8H26_RS21330	COG3781	membrane
A8H26_RS21335	COG0826	peptidase U32
A8H26_RS21345	COG1830	Aldolase
A8H26_RS21350	COG0351	phosphomethylpyrimidine kinase
A8H26_RS21435	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A8H26_RS21440	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A8H26_RS21455	COG1735	metal-dependent hydrolase with the TIM-barrel fold
A8H26_RS21460	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A8H26_RS21465	COG3457	Alanine racemase
A8H26_RS21470	COG2188	Transcriptional regulator
A8H26_RS21485	COG0583	DNA-binding transcription factor activity
A8H26_RS21495	COG2252	PERMEase
A8H26_RS21500	COG0640	Transcriptional regulator
A8H26_RS21515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A8H26_RS21525	COG0531	amino acid
A8H26_RS21565	COG5455	response to cobalt ion
A8H26_RS21580	COG0489	protein tyrosine kinase activity
A8H26_RS21590	COG4808	Protein conserved in bacteria
A8H26_RS21595	COG2814	Major facilitator Superfamily
A8H26_RS21600	COG4807	Protein conserved in bacteria
A8H26_RS21610	COG3275	phosphorelay sensor kinase activity
A8H26_RS21620	COG1174	glycine betaine transport
A8H26_RS21625	COG1125	glycine betaine transport
A8H26_RS21630	COG1174	glycine betaine transport
A8H26_RS21635	COG1732	Glycine betaine
A8H26_RS21640	COG1472	Belongs to the glycosyl hydrolase 3 family
A8H26_RS21645	COG0277	FAD linked oxidase domain protein
A8H26_RS21665	COG1686	Belongs to the peptidase S11 family
A8H26_RS21675	COG0586	Pfam SNARE associated Golgi protein
A8H26_RS21680	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS21685	COG2226	methyltransferase
A8H26_RS21690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A8H26_RS21695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8H26_RS21700	COG0625	glutathione transferase activity
A8H26_RS21715	COG2271	Major facilitator Superfamily
A8H26_RS21730	COG1346	cytolysis
A8H26_RS21740	COG2949	membrane
A8H26_RS21750	COG1129	ABC transporter
A8H26_RS21760	COG1609	Transcriptional regulator
A8H26_RS21770	COG2311	Membrane
A8H26_RS21775	COG0302	gtp cyclohydrolase
A8H26_RS21790	COG4771	TonB-dependent receptor
A8H26_RS21795	COG0833	amino acid
A8H26_RS21805	COG0765	amino acid transport
A8H26_RS21820	COG0583	DNA-binding transcription factor activity
A8H26_RS21825	COG2855	membrane
A8H26_RS21830	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A8H26_RS21840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8H26_RS21840	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A8H26_RS21840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8H26_RS21845	COG1105	Belongs to the carbohydrate kinase PfkB family
A8H26_RS21850	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8H26_RS21850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8H26_RS21860	COG2814	Major facilitator Superfamily
A8H26_RS21865	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A8H26_RS21870	COG1397	ADP-ribosylglycohydrolase
A8H26_RS21885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A8H26_RS21890	COG3083	sulfuric ester hydrolase activity
A8H26_RS21895	COG1312	Catalyzes the dehydration of D-mannonate
A8H26_RS21900	COG0246	Mannitol dehydrogenase
A8H26_RS21905	COG0523	cobalamin synthesis protein
A8H26_RS21910	COG0671	phosphoesterase, PA-phosphatase related
A8H26_RS21915	COG0791	NLP P60 protein
A8H26_RS21920	COG4166	transmembrane transport
A8H26_RS21925	COG4174	ABC transporter (Permease)
A8H26_RS21930	COG4239	(ABC) transporter, permease
A8H26_RS21935	COG4172	Belongs to the ABC transporter superfamily
A8H26_RS21945	COG2814	Major facilitator Superfamily
A8H26_RS21950	COG1187	pseudouridine synthase activity
A8H26_RS21955	COG1061	Type III restriction enzyme res subunit
A8H26_RS22005	COG1802	Transcriptional regulator
A8H26_RS22035	COG1942	4-Oxalocrotonate Tautomerase
A8H26_RS22040	COG4569	acetaldehyde dehydrogenase (acetylating) activity
A8H26_RS22055	COG0659	secondary active sulfate transmembrane transporter activity
A8H26_RS22060	COG2239	Acts as a magnesium transporter
A8H26_RS22065	COG4615	Cyclic peptide transporter
A8H26_RS22070	COG3145	DNA-N1-methyladenine dioxygenase activity
A8H26_RS22085	COG0642	Histidine kinase
A8H26_RS22085	COG2198	Histidine kinase
A8H26_RS22090	COG2197	response regulator
A8H26_RS22095	COG2205	protein histidine kinase activity
A8H26_RS22095	COG0784	Response regulator, receiver
A8H26_RS22115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A8H26_RS22125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8H26_RS22135	COG0584	glycerophosphoryl diester phosphodiesterase
A8H26_RS22140	COG2271	Major facilitator Superfamily
A8H26_RS22145	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A8H26_RS22155	COG0247	lactate metabolic process
A8H26_RS22160	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS22205	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A8H26_RS22220	COG1169	isochorismate synthase
A8H26_RS22225	COG4575	ribosome binding
A8H26_RS22230	COG2153	protein acetylation
A8H26_RS22240	COG0784	Response regulator, receiver
A8H26_RS22240	COG0835	chemotaxis
A8H26_RS22260	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8H26_RS22265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A8H26_RS22275	COG0839	Belongs to the complex I subunit 6 family
A8H26_RS22295	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A8H26_RS22320	COG0583	DNA-binding transcription factor activity
A8H26_RS22325	COG0436	Aminotransferase
A8H26_RS22335	COG2207	Transcriptional regulator
A8H26_RS22345	COG4656	Part of a membrane complex involved in electron transport
A8H26_RS22355	COG4816	utilization protein
A8H26_RS22365	COG4303	Ethanolamine ammonia lyase large subunit
A8H26_RS22370	COG4819	ethanolamine utilization protein
A8H26_RS22395	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
A8H26_RS22405	COG0280	phosphate acetyltransferase
A8H26_RS22410	COG4812	Cobalamin adenosyltransferase
A8H26_RS22425	COG4810	utilization protein
A8H26_RS22430	COG0490	domain, Protein
A8H26_RS22430	COG0471	metal ion transport
A8H26_RS22435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8H26_RS22455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A8H26_RS22470	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A8H26_RS22475	COG3959	Transketolase, thiamine diphosphate binding domain
A8H26_RS22480	COG3037	sugar-specific permease SgaT UlaA
A8H26_RS22490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8H26_RS22495	COG1609	Transcriptional regulator
A8H26_RS22500	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
A8H26_RS22505	COG0622	Phosphoesterase
A8H26_RS22510	COG0625	glutathione transferase activity
A8H26_RS22515	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A8H26_RS22520	COG1090	epimerase
A8H26_RS22545	COG1070	Carbohydrate kinase
A8H26_RS22550	COG0246	Mannitol dehydrogenase
A8H26_RS22560	COG4598	ABC transporter
A8H26_RS22565	COG4160	amino acid transport
A8H26_RS22570	COG4215	(ABC) transporter
A8H26_RS22585	COG0163	prenyltransferase activity
A8H26_RS22590	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A8H26_RS22595	COG1286	toxin biosynthetic process
A8H26_RS22600	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
A8H26_RS22605	COG0285	dihydrofolate synthase activity
A8H26_RS22615	COG0586	Pfam SNARE associated Golgi protein
A8H26_RS22625	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A8H26_RS22645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A8H26_RS22655	COG2223	nitrite transmembrane transporter activity
A8H26_RS22675	COG3101	peptidyl-lysine hydroxylation
A8H26_RS22680	COG0730	response to heat
A8H26_RS22705	COG2062	phosphohistidine phosphatase, SixA
A8H26_RS22720	COG3691	Protein conserved in bacteria
A8H26_RS22735	COG2853	Lipoprotein
A8H26_RS22740	COG2116	formate transmembrane transporter activity
A8H26_RS22765	COG1215	transferase activity, transferring glycosyl groups
A8H26_RS22770	COG4783	chaperone-mediated protein folding
A8H26_RS22785	COG0436	Aminotransferase
A8H26_RS22790	COG3275	phosphorelay sensor kinase activity
A8H26_RS22795	COG3279	Response regulator of the LytR AlgR family
A8H26_RS22805	COG3961	Belongs to the TPP enzyme family
A8H26_RS22810	COG0667	Aldo Keto reductase
A8H26_RS22830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8H26_RS22845	COG3415	Transposase
A8H26_RS22850	COG3415	Transposase
A8H26_RS22900	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A8H26_RS22905	COG1116	anion transmembrane transporter activity
A8H26_RS22910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8H26_RS22915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8H26_RS22920	COG0583	DNA-binding transcription factor activity
A8H26_RS22925	COG0385	Bile acid
A8H26_RS22930	COG3530	Putative quorum-sensing-regulated virulence factor
A8H26_RS22955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8H26_RS22980	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A8H26_RS22985	COG4208	sulfate ABC transporter
A8H26_RS22990	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A8H26_RS22995	COG4150	thiosulfate binding
A8H26_RS23000	COG2837	iron assimilation
A8H26_RS23025	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8H26_RS23045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A8H26_RS23050	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A8H26_RS23060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8H26_RS23070	COG1393	Belongs to the ArsC family
A8H26_RS23085	COG0400	carboxylic ester hydrolase activity
A8H26_RS23095	COG2321	neutral zinc metallopeptidase
A8H26_RS23100	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A8H26_RS23105	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
A8H26_RS23115	COG2716	regulation of RNA biosynthetic process
A8H26_RS23120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A8H26_RS23125	COG1879	ABC-type sugar transport system periplasmic component
A8H26_RS23130	COG1129	ABC transporter
A8H26_RS23135	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8H26_RS23145	COG1929	Belongs to the glycerate kinase type-1 family
A8H26_RS23150	COG2610	gluconate transmembrane transporter activity
A8H26_RS23155	COG3835	regulator
A8H26_RS23160	COG0628	permease
A8H26_RS23165	COG4783	chaperone-mediated protein folding
A8H26_RS23170	COG1393	Belongs to the ArsC family
A8H26_RS23185	COG1446	asparaginase
A8H26_RS23205	COG2233	PERMEase
A8H26_RS23215	COG2723	6-phospho-beta-galactosidase activity
A8H26_RS23225	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A8H26_RS23240	COG2200	EAL domain
A8H26_RS23295	COG0516	GMP reductase activity
A8H26_RS23295	COG0517	IMP dehydrogenase activity
A8H26_RS23305	COG1645	bacterial-type flagellum-dependent swarming motility
A8H26_RS23325	COG2976	Protein conserved in bacteria
A8H26_RS23355	COG4953	penicillin-binding protein 1C
A8H26_RS23360	COG2373	Large extracellular alpha-helical protein
A8H26_RS23365	COG2897	thiosulfate sulfurtransferase activity
A8H26_RS23380	COG2975	iron-sulfur cluster assembly
A8H26_RS23385	COG0633	Ferredoxin
A8H26_RS23405	COG0822	iron-sulfur transferase activity
A8H26_RS23430	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
A8H26_RS23440	COG3711	transcriptional antiterminator
A8H26_RS23445	COG2814	Major facilitator Superfamily
A8H26_RS23455	COG1129	ABC transporter
A8H26_RS23460	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8H26_RS23470	COG1069	ribulokinase activity
A8H26_RS23475	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A8H26_RS23475	COG0517	IMP dehydrogenase activity
A8H26_RS23480	COG2259	Doxx family
A8H26_RS23495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8H26_RS23495	COG1017	nitric oxide dioxygenase activity
A8H26_RS23500	COG3710	Transcriptional regulator
A8H26_RS23505	COG0531	amino acid
A8H26_RS23515	COG3104	oligopeptide transport
A8H26_RS23520	COG0347	Belongs to the P(II) protein family
A8H26_RS23525	COG2204	response regulator
A8H26_RS23530	COG3170	Tfp pilus assembly protein FimV
A8H26_RS23535	COG2205	protein histidine kinase activity
A8H26_RS23540	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A8H26_RS23540	COG0047	phosphoribosylformylglycinamidine synthase activity
A8H26_RS23555	COG0560	Phosphoserine phosphatase
A8H26_RS23560	COG1737	Transcriptional regulator
A8H26_RS23575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8H26_RS23585	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A8H26_RS23610	COG0681	Belongs to the peptidase S26 family
A8H26_RS23620	COG3086	response to oxidative stress
A8H26_RS23630	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
A8H26_RS23640	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A8H26_RS23650	COG0513	Belongs to the DEAD box helicase family
A8H26_RS23665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8H26_RS23670	COG3118	belongs to the thioredoxin family
A8H26_RS23675	COG3148	PFAM DTW domain containing protein
A8H26_RS23680	COG0045	succinate-CoA ligase (ADP-forming) activity
A8H26_RS23680	COG1042	CoA-binding domain protein
A8H26_RS23680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8H26_RS23685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8H26_RS23690	COG5544	Lipoprotein
A8H26_RS23695	COG0477	Major facilitator Superfamily
A8H26_RS23720	COG0542	response to heat
A8H26_RS23730	COG0564	pseudouridine synthase activity
A8H26_RS23735	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8H26_RS23740	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A8H26_RS23750	COG1605	Chorismate mutase
A8H26_RS23750	COG0077	Prephenate dehydratase
A8H26_RS23765	COG1605	Chorismate mutase
A8H26_RS23765	COG0287	Prephenate dehydrogenase
A8H26_RS23770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A8H26_RS23785	COG2140	Oxalate decarboxylase
A8H26_RS23805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A8H26_RS23870	COG5301	cellulose 1,4-beta-cellobiosidase activity
A8H26_RS23945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A8H26_RS23950	COG4137	Cytochrome C assembly protein
A8H26_RS23955	COG4536	flavin adenine dinucleotide binding
A8H26_RS23970	COG0497	DNA recombination
A8H26_RS23985	COG2867	negative regulation of translational initiation
A8H26_RS24030	COG0247	lactate metabolic process
A8H26_RS24035	COG1139	Iron-sulfur cluster binding protein
A8H26_RS24040	COG1556	Lactate utilization protein
A8H26_RS24065	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS24080	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
A8H26_RS24085	COG0747	negative chemotaxis
A8H26_RS24090	COG0601	transmembrane transport
A8H26_RS24095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8H26_RS24100	COG0444	Belongs to the ABC transporter superfamily
A8H26_RS24105	COG4608	Belongs to the ABC transporter superfamily
A8H26_RS24110	COG1802	Transcriptional regulator
A8H26_RS24125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8H26_RS24140	COG3592	Divergent 4Fe-4S mono-cluster
A8H26_RS24145	COG2388	GCN5-related N-acetyl-transferase
A8H26_RS24150	COG0583	DNA-binding transcription factor activity
A8H26_RS24160	COG0401	homolog of Blt101
A8H26_RS24180	COG4575	ribosome binding
A8H26_RS24190	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8H26_RS24205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A8H26_RS24210	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A8H26_RS24220	COG4176	ABC-type proline glycine betaine transport system permease component
A8H26_RS24235	COG4176	ABC-type proline glycine betaine transport system permease component
A8H26_RS24245	COG2814	Major facilitator Superfamily
A8H26_RS24250	COG1846	Transcriptional regulator
A8H26_RS24255	COG1566	PFAM secretion protein HlyD family protein
A8H26_RS24260	COG2814	Major facilitator Superfamily
A8H26_RS24265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A8H26_RS24290	COG1238	metal cluster binding
A8H26_RS24295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8H26_RS24330	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A8H26_RS24350	COG1546	Belongs to the CinA family
A8H26_RS24355	COG0803	Belongs to the bacterial solute-binding protein 9 family
A8H26_RS24360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8H26_RS24370	COG2951	lytic endotransglycosylase activity
A8H26_RS24390	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A8H26_RS24395	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A8H26_RS24400	COG3383	formate dehydrogenase (NAD+) activity
A8H26_RS24405	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8H26_RS24430	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A8H26_RS24440	COG3260	NADH ubiquinone oxidoreductase 20
A8H26_RS24445	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8H26_RS24450	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A8H26_RS24450	COG3261	NADH dehydrogenase
A8H26_RS24455	COG0650	Formate hydrogenlyase subunit 4
A8H26_RS24460	COG0651	ATP synthesis coupled electron transport
A8H26_RS24465	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8H26_RS24480	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A8H26_RS24485	COG0298	carbon dioxide binding
A8H26_RS24490	COG0409	Hydrogenase expression formation protein
A8H26_RS24495	COG0309	Hydrogenase expression formation protein (HypE)
A8H26_RS24505	COG3585	molybdate ion transport
A8H26_RS24505	COG2005	Transcriptional regulator
A8H26_RS24515	COG2207	Transcriptional regulator
A8H26_RS24525	COG1414	Transcriptional regulator
A8H26_RS24560	COG2814	Major facilitator Superfamily
A8H26_RS24565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8H26_RS24570	COG1454	alcohol dehydrogenase
A8H26_RS24595	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A8H26_RS24600	COG0163	prenyltransferase activity
A8H26_RS24610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A8H26_RS24620	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A8H26_RS24675	COG2234	aminopeptidase activity
A8H26_RS24680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8H26_RS24685	COG1518	maintenance of DNA repeat elements
A8H26_RS24700	COG1857	crispr-associated protein
A8H26_RS24715	COG1203	CRISPR-associated helicase, Cas3
A8H26_RS24750	COG0720	synthase
A8H26_RS24755	COG0602	queuosine metabolic process
A8H26_RS24770	COG3956	TIGRFAM MazG family protein
A8H26_RS24775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A8H26_RS24785	COG2205	protein histidine kinase activity
A8H26_RS24785	COG3437	response regulator, receiver
A8H26_RS24785	COG3850	Histidine kinase
A8H26_RS24785	COG4999	Histidine kinase
A8H26_RS24790	COG0716	FMN binding
A8H26_RS24795	COG0564	pseudouridine synthase activity
A8H26_RS24800	COG3098	single-species biofilm formation
A8H26_RS24805	COG3311	Transcriptional regulator
A8H26_RS24820	COG1611	Belongs to the LOG family
A8H26_RS24825	COG0814	amino acid
A8H26_RS24830	COG1760	l-serine dehydratase
A8H26_RS24835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8H26_RS24845	COG2814	Major facilitator Superfamily
A8H26_RS24865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8H26_RS24875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8H26_RS24890	COG2363	Small membrane protein
A8H26_RS24895	COG0583	DNA-binding transcription factor activity
A8H26_RS24905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A8H26_RS24910	COG2166	iron-sulfur cluster assembly
A8H26_RS24915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A8H26_RS24920	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
A8H26_RS24940	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8H26_RS24945	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A8H26_RS24945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A8H26_RS24960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A8H26_RS24965	COG1074	ATP-dependent DNA helicase activity
A8H26_RS24970	COG1025	Belongs to the peptidase M16 family
A8H26_RS24975	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A8H26_RS24980	COG4967	type IV pilus modification protein PilV
A8H26_RS24990	COG4795	General secretion pathway protein
A8H26_RS24995	COG2165	general secretion pathway protein
A8H26_RS25025	COG0861	Integral membrane protein TerC family
A8H26_RS25035	COG0667	Aldo Keto reductase
A8H26_RS25045	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS25050	COG1250	3-hydroxyacyl-CoA dehydrogenase
A8H26_RS25055	COG2031	fatty acid transporter
A8H26_RS25080	COG1609	Transcriptional regulator
A8H26_RS25090	COG1609	Transcriptional regulator
A8H26_RS25100	COG0583	DNA-binding transcription factor activity
A8H26_RS25105	COG1794	racemase activity, acting on amino acids and derivatives
A8H26_RS25110	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS25200	COG3284	Transcriptional regulator
A8H26_RS25205	COG0183	Belongs to the thiolase family
A8H26_RS25210	COG0814	amino acid
A8H26_RS25215	COG0667	Aldo Keto reductase
A8H26_RS25240	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A8H26_RS25260	COG3659	wide pore channel activity
A8H26_RS25270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A8H26_RS25275	COG2070	2-Nitropropane dioxygenase
A8H26_RS25295	COG0583	DNA-binding transcription factor activity
A8H26_RS25300	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A8H26_RS25310	COG1811	Na channel or pump
A8H26_RS25330	COG0386	Belongs to the glutathione peroxidase family
A8H26_RS25350	COG2801	Transposase and inactivated derivatives
A8H26_RS25455	COG4974	Belongs to the 'phage' integrase family
A8H26_RS25525	COG0582	viral genome integration into host DNA
A8H26_RS25535	COG4942	peptidase
A8H26_RS25555	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A8H26_RS25565	COG4974	Belongs to the 'phage' integrase family
A8H26_RS25580	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
A8H26_RS25610	COG1272	protein, Hemolysin III
A8H26_RS25620	COG1737	Transcriptional regulator
A8H26_RS25625	COG2723	6-phospho-beta-galactosidase activity
A8H26_RS25630	COG1028	Short-chain dehydrogenase reductase Sdr
A8H26_RS25650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8H26_RS25655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8H26_RS25660	COG0006	proline dipeptidase activity
A8H26_RS25680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A8H26_RS25685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A8H26_RS25700	COG2968	Membrane
A8H26_RS25705	COG1279	arginine transmembrane transporter activity
A8H26_RS25710	COG0668	transmembrane transport
A8H26_RS25715	COG0191	fructose-bisphosphate aldolase activity