locus-tag	class	description
A0W33_RS00015	COG0124	histidyl-tRNA synthetase
A0W33_RS00020	COG2986	histidine ammonia-lyase
A0W33_RS00030	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A0W33_RS00050	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0W33_RS00050	COG0022	dehydrogenase e1 component
A0W33_RS00070	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A0W33_RS00080	COG1131	(ABC) transporter
A0W33_RS00085	COG2972	Histidine kinase
A0W33_RS00090	COG3279	Response regulator of the LytR AlgR family
A0W33_RS00095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A0W33_RS00110	COG1278	Cold shock
A0W33_RS00185	COG1127	ABC transporter
A0W33_RS00190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A0W33_RS00210	COG3228	Belongs to the MtfA family
A0W33_RS00225	COG0022	dehydrogenase e1 component
A0W33_RS00260	COG2270	Major facilitator Superfamily
A0W33_RS00275	COG0747	negative chemotaxis
A0W33_RS00285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0W33_RS00290	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
A0W33_RS00295	COG0745	RESPONSE REGULATOR receiver
A0W33_RS00300	COG2205	protein histidine kinase activity
A0W33_RS00300	COG0784	Response regulator, receiver
A0W33_RS00305	COG0784	Response regulator, receiver
A0W33_RS00310	COG4191	Histidine kinase
A0W33_RS00345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A0W33_RS00365	COG0720	synthase
A0W33_RS00460	COG0348	domain, Protein
A0W33_RS00475	COG3278	Belongs to the heme-copper respiratory oxidase family
A0W33_RS00485	COG2217	Heavy metal translocating P-type atpase
A0W33_RS00490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A0W33_RS00510	COG2205	protein histidine kinase activity
A0W33_RS00510	COG2198	Histidine kinase
A0W33_RS00510	COG0784	Response regulator, receiver
A0W33_RS00520	COG0745	RESPONSE REGULATOR receiver
A0W33_RS00525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A0W33_RS00545	COG0463	Glycosyl transferase, family 2
A0W33_RS00545	COG1216	Glycosyl transferase, family 2
A0W33_RS00560	COG0110	maltose O-acetyltransferase activity
A0W33_RS00570	COG1215	transferase activity, transferring glycosyl groups
A0W33_RS00575	COG2244	polysaccharide biosynthetic process
A0W33_RS00635	COG0438	transferase activity, transferring glycosyl groups
A0W33_RS00655	COG1215	transferase activity, transferring glycosyl groups
A0W33_RS00660	COG0726	polysaccharide deacetylase
A0W33_RS00665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A0W33_RS00670	COG1216	Glycosyl transferase, family 2
A0W33_RS00700	COG0252	asparaginase activity
A0W33_RS00705	COG0084	hydrolase, TatD family'
A0W33_RS00710	COG1215	transferase activity, transferring glycosyl groups
A0W33_RS00725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0W33_RS00735	COG1215	transferase activity, transferring glycosyl groups
A0W33_RS00745	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
A0W33_RS00755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A0W33_RS00760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A0W33_RS00765	COG2239	Acts as a magnesium transporter
A0W33_RS00770	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A0W33_RS00775	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A0W33_RS00780	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A0W33_RS00790	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A0W33_RS00795	COG0416	fatty acid biosynthetic process
A0W33_RS00800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A0W33_RS00815	COG1030	water channel activity
A0W33_RS00830	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
A0W33_RS00840	COG1597	lipid kinase activity
A0W33_RS00860	COG1917	Cupin 2, conserved barrel domain protein
A0W33_RS00860	COG4977	sequence-specific DNA binding
A0W33_RS00865	COG4221	oxidoreductase activity
A0W33_RS00880	COG0628	permease
A0W33_RS00900	COG4771	TonB-dependent receptor
A0W33_RS00920	COG1131	(ABC) transporter
A0W33_RS00925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A0W33_RS00975	COG4095	Psort location CytoplasmicMembrane, score
A0W33_RS00980	COG1741	Belongs to the pirin family
A0W33_RS00990	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A0W33_RS01000	COG1309	transcriptional regulator
A0W33_RS01005	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A0W33_RS01020	COG3279	Response regulator of the LytR AlgR family
A0W33_RS01025	COG3275	phosphorelay sensor kinase activity
A0W33_RS01045	COG0626	cystathionine gamma-synthase activity
A0W33_RS01055	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS01065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A0W33_RS01105	COG2201	protein-glutamate methylesterase activity
A0W33_RS01120	COG2197	response regulator
A0W33_RS01125	COG1446	asparaginase
A0W33_RS01135	COG1022	Amp-dependent synthetase and ligase
A0W33_RS01150	COG1408	metallophosphoesterase
A0W33_RS01165	COG1278	Cold shock
A0W33_RS01170	COG0577	efflux transmembrane transporter activity
A0W33_RS01170	COG1136	(ABC) transporter
A0W33_RS01175	COG2204	response regulator
A0W33_RS01180	COG4191	Histidine kinase
A0W33_RS01200	COG1643	Atp-dependent helicase
A0W33_RS01205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0W33_RS01215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W33_RS01235	COG2252	PERMEase
A0W33_RS01275	COG0714	Associated with various cellular activities
A0W33_RS01305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A0W33_RS01310	COG0791	NLP P60 protein
A0W33_RS01315	COG0156	8-amino-7-oxononanoate synthase activity
A0W33_RS01320	COG4948	Mandelate Racemase Muconate Lactonizing
A0W33_RS01330	COG0363	glucosamine-6-phosphate deaminase activity
A0W33_RS01365	COG1472	Belongs to the glycosyl hydrolase 3 family
A0W33_RS01370	COG1649	PFAM Uncharacterised BCR, COG1649
A0W33_RS01385	COG1914	H( )-stimulated, divalent metal cation uptake system
A0W33_RS01390	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A0W33_RS01395	COG1984	allophanate hydrolase subunit 2
A0W33_RS01400	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A0W33_RS01405	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
A0W33_RS01425	COG0406	alpha-ribazole phosphatase activity
A0W33_RS01430	COG2050	protein possibly involved in aromatic compounds catabolism
A0W33_RS01440	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
A0W33_RS01455	COG0318	PFAM AMP-dependent synthetase and ligase
A0W33_RS01485	COG0010	Belongs to the arginase family
A0W33_RS01490	COG1228	amidohydrolase
A0W33_RS01500	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
A0W33_RS01505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A0W33_RS01510	COG3386	PFAM SMP-30 Gluconolaconase
A0W33_RS01520	COG4654	Cytochrome c, class I
A0W33_RS01545	COG1187	pseudouridine synthase activity
A0W33_RS01550	COG1187	pseudouridine synthase activity
A0W33_RS01570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A0W33_RS01575	COG0596	Alpha beta hydrolase
A0W33_RS01585	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS01595	COG1215	transferase activity, transferring glycosyl groups
A0W33_RS01605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A0W33_RS01635	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A0W33_RS01640	COG1629	transport
A0W33_RS01640	COG4206	TonB-dependent receptor
A0W33_RS01650	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A0W33_RS01655	COG0784	Response regulator, receiver
A0W33_RS01655	COG4191	Histidine kinase
A0W33_RS01675	COG1902	pentaerythritol trinitrate reductase activity
A0W33_RS01690	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A0W33_RS01715	COG4771	TonB-dependent receptor
A0W33_RS01720	COG0702	epimerase
A0W33_RS01745	COG0004	ammonium transporteR
A0W33_RS01750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0W33_RS01750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A0W33_RS01790	COG0492	ferredoxin-NADP+ reductase activity
A0W33_RS01825	COG0300	oxidoreductase activity
A0W33_RS01830	COG1012	belongs to the aldehyde dehydrogenase family
A0W33_RS01835	COG1253	flavin adenine dinucleotide binding
A0W33_RS01840	COG0590	tRNA wobble adenosine to inosine editing
A0W33_RS01845	COG0702	epimerase
A0W33_RS01850	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A0W33_RS01860	COG1234	tRNA 3'-trailer cleavage
A0W33_RS01875	COG0180	Tryptophanyl-tRNA synthetase
A0W33_RS01915	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A0W33_RS01920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A0W33_RS01925	COG0778	Nitroreductase
A0W33_RS01930	COG0126	phosphoglycerate kinase activity
A0W33_RS01935	COG0154	amidase activity
A0W33_RS01970	COG4628	conserved protein (DUF2132)
A0W33_RS01980	COG0514	ATP-dependent DNA helicase (RecQ)
A0W33_RS01990	COG1136	(ABC) transporter
A0W33_RS02000	COG0045	succinate-CoA ligase (ADP-forming) activity
A0W33_RS02005	COG1764	response to oxidative stress
A0W33_RS02025	COG1366	Belongs to the anti-sigma-factor antagonist family
A0W33_RS02030	COG1366	Belongs to the anti-sigma-factor antagonist family
A0W33_RS02035	COG2172	sigma factor antagonist activity
A0W33_RS02050	COG2201	protein-glutamate methylesterase activity
A0W33_RS02060	COG1012	belongs to the aldehyde dehydrogenase family
A0W33_RS02085	COG2226	methyltransferase
A0W33_RS02105	COG0110	maltose O-acetyltransferase activity
A0W33_RS02115	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A0W33_RS02135	COG1053	succinate dehydrogenase
A0W33_RS02140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A0W33_RS02145	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A0W33_RS02150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A0W33_RS02165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A0W33_RS02170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A0W33_RS02175	COG0772	Belongs to the SEDS family
A0W33_RS02180	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A0W33_RS02185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A0W33_RS02190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A0W33_RS02195	COG0768	penicillin binding
A0W33_RS02205	COG0275	rRNA processing
A0W33_RS02210	COG2001	Belongs to the MraZ family
A0W33_RS02240	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A0W33_RS02265	COG1595	DNA-templated transcription, initiation
A0W33_RS02285	COG1309	transcriptional regulator
A0W33_RS02290	COG3396	Phenylacetate-CoA oxygenase
A0W33_RS02305	COG2151	metal-sulfur cluster biosynthetic enzyme
A0W33_RS02315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A0W33_RS02315	COG1017	nitric oxide dioxygenase activity
A0W33_RS02330	COG0668	transmembrane transport
A0W33_RS02340	COG3876	Protein conserved in bacteria
A0W33_RS02345	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A0W33_RS02350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A0W33_RS02365	COG1695	Transcriptional regulator
A0W33_RS02380	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A0W33_RS02380	COG0617	tRNA 3'-terminal CCA addition
A0W33_RS02380	COG0517	IMP dehydrogenase activity
A0W33_RS02385	COG0009	L-threonylcarbamoyladenylate synthase
A0W33_RS02390	COG0346	lactoylglutathione lyase activity
A0W33_RS02395	COG1104	cysteine desulfurase activity
A0W33_RS02400	COG0822	iron-sulfur transferase activity
A0W33_RS02410	COG0316	Belongs to the HesB IscA family
A0W33_RS02430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A0W33_RS02435	COG0420	3'-5' exonuclease activity
A0W33_RS02440	COG0419	ATPase involved in DNA repair
A0W33_RS02445	COG0784	Response regulator, receiver
A0W33_RS02445	COG2205	protein histidine kinase activity
A0W33_RS02470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A0W33_RS02480	COG0477	Major facilitator Superfamily
A0W33_RS02500	COG1462	curli production assembly transport component CsgG
A0W33_RS02535	COG3118	belongs to the thioredoxin family
A0W33_RS02540	COG4191	Histidine kinase
A0W33_RS02555	COG0577	efflux transmembrane transporter activity
A0W33_RS02555	COG1136	(ABC) transporter
A0W33_RS02560	COG1136	(ABC) transporter
A0W33_RS02560	COG0577	efflux transmembrane transporter activity
A0W33_RS02570	COG0577	efflux transmembrane transporter activity
A0W33_RS02570	COG1136	(ABC) transporter
A0W33_RS02575	COG1136	(ABC) transporter
A0W33_RS02575	COG0577	efflux transmembrane transporter activity
A0W33_RS02625	COG0616	signal peptide processing
A0W33_RS02630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A0W33_RS02635	COG0628	permease
A0W33_RS02645	COG0513	Belongs to the DEAD box helicase family
A0W33_RS02650	COG3384	dioxygenase
A0W33_RS02655	COG0492	ferredoxin-NADP+ reductase activity
A0W33_RS02665	COG2201	protein-glutamate methylesterase activity
A0W33_RS02680	COG3239	Fatty acid desaturase
A0W33_RS02685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A0W33_RS02690	COG0739	heme binding
A0W33_RS02695	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS02705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A0W33_RS02710	COG1187	pseudouridine synthase activity
A0W33_RS02730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A0W33_RS02750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W33_RS02760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A0W33_RS02775	COG0471	metal ion transport
A0W33_RS02800	COG1741	Belongs to the pirin family
A0W33_RS02805	COG0778	Nitroreductase
A0W33_RS02815	COG1051	belongs to the nudix hydrolase family
A0W33_RS02820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A0W33_RS02845	COG0438	transferase activity, transferring glycosyl groups
A0W33_RS02850	COG0673	inositol 2-dehydrogenase activity
A0W33_RS02855	COG1063	alcohol dehydrogenase
A0W33_RS02860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0W33_RS02885	COG4771	TonB-dependent receptor
A0W33_RS02890	COG0702	epimerase
A0W33_RS02895	COG3682	Transcriptional regulator
A0W33_RS02905	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
A0W33_RS02920	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A0W33_RS02975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A0W33_RS02975	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A0W33_RS02980	COG1215	transferase activity, transferring glycosyl groups
A0W33_RS02985	COG0358	DNA primase activity
A0W33_RS02995	COG0489	protein tyrosine kinase activity
A0W33_RS03000	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A0W33_RS03010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0W33_RS03020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A0W33_RS03030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A0W33_RS03050	COG0367	asparagine synthase
A0W33_RS03060	COG0297	glycogen (starch) synthase activity
A0W33_RS03065	COG1216	Glycosyl transferase, family 2
A0W33_RS03070	COG0438	transferase activity, transferring glycosyl groups
A0W33_RS03075	COG0438	transferase activity, transferring glycosyl groups
A0W33_RS03100	COG1132	(ABC) transporter
A0W33_RS03120	COG1083	cytidylyl-transferase
A0W33_RS03125	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A0W33_RS03130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A0W33_RS03135	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A0W33_RS03145	COG2089	acid synthase
A0W33_RS03150	COG0110	maltose O-acetyltransferase activity
A0W33_RS03155	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A0W33_RS03160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0W33_RS03180	COG2852	Protein conserved in bacteria
A0W33_RS03185	COG0802	atpase or kinase
A0W33_RS03190	COG2204	response regulator
A0W33_RS03195	COG1078	dGTPase activity
A0W33_RS03200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A0W33_RS03205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A0W33_RS03205	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
A0W33_RS03210	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A0W33_RS03215	COG1131	(ABC) transporter
A0W33_RS03220	COG0217	transcriptional regulatory protein
A0W33_RS03240	COG1058	Belongs to the CinA family
A0W33_RS03240	COG1546	Belongs to the CinA family
A0W33_RS03245	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0W33_RS03260	COG1196	nuclear chromosome segregation
A0W33_RS03260	COG3264	Mechanosensitive ion channel
A0W33_RS03265	COG0443	Heat shock 70 kDa protein
A0W33_RS03280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A0W33_RS03285	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A0W33_RS03290	COG2095	MarC family integral membrane protein
A0W33_RS03295	COG2095	MarC family integral membrane protein
A0W33_RS03300	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A0W33_RS03305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A0W33_RS03310	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A0W33_RS03310	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A0W33_RS03315	COG0436	Aminotransferase
A0W33_RS03330	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A0W33_RS03380	COG1301	dicarboxylic acid transport
A0W33_RS03405	COG1228	amidohydrolase
A0W33_RS03410	COG0612	Peptidase, M16
A0W33_RS03425	COG1714	RDD family
A0W33_RS03455	COG0671	phosphoesterase, PA-phosphatase related
A0W33_RS03460	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A0W33_RS03465	COG1058	Belongs to the CinA family
A0W33_RS03465	COG1546	Belongs to the CinA family
A0W33_RS03485	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A0W33_RS03490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A0W33_RS03495	COG1132	(ABC) transporter
A0W33_RS03510	COG2226	methyltransferase
A0W33_RS03565	COG0531	amino acid
A0W33_RS03590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0W33_RS03590	COG2022	thiamine diphosphate biosynthetic process
A0W33_RS03605	COG1428	Deoxynucleoside kinase
A0W33_RS03635	COG2963	transposase activity
A0W33_RS03640	COG2801	Transposase and inactivated derivatives
A0W33_RS03650	COG4251	negative regulation of phosphorylation
A0W33_RS03655	COG2198	Histidine kinase
A0W33_RS03655	COG0643	Histidine kinase
A0W33_RS03680	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS03715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A0W33_RS03725	COG2885	chlorophyll binding
A0W33_RS03725	COG3047	cAMP biosynthetic process
A0W33_RS03735	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A0W33_RS03740	COG0514	ATP-dependent DNA helicase (RecQ)
A0W33_RS03745	COG0514	ATP-dependent DNA helicase (RecQ)
A0W33_RS03760	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
A0W33_RS03815	COG4771	TonB-dependent receptor
A0W33_RS03830	COG0604	alcohol dehydrogenase
A0W33_RS03835	COG0456	acetyltransferase
A0W33_RS03840	COG1404	Belongs to the peptidase S8 family
A0W33_RS03845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A0W33_RS03850	COG3590	peptidase
A0W33_RS03885	COG1528	Iron-storage protein
A0W33_RS03905	COG3279	Response regulator of the LytR AlgR family
A0W33_RS03910	COG3275	phosphorelay sensor kinase activity
A0W33_RS03930	COG4771	TonB-dependent receptor
A0W33_RS03945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A0W33_RS03950	COG1566	PFAM secretion protein HlyD family protein
A0W33_RS03955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A0W33_RS03965	COG3174	membrane
A0W33_RS03985	COG2271	Major facilitator Superfamily
A0W33_RS03990	COG1904	glucuronate isomerase
A0W33_RS03995	COG1312	Catalyzes the dehydration of D-mannonate
A0W33_RS04005	COG1629	transport
A0W33_RS04015	COG3661	Belongs to the glycosyl hydrolase 67 family
A0W33_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS04030	COG1070	Carbohydrate kinase
A0W33_RS04040	COG0477	Major facilitator Superfamily
A0W33_RS04040	COG2814	Major facilitator Superfamily
A0W33_RS04045	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS04050	COG0405	Gamma-glutamyltransferase
A0W33_RS04080	COG0849	cell division
A0W33_RS04120	COG0824	Thioesterase
A0W33_RS04125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A0W33_RS04130	COG0009	L-threonylcarbamoyladenylate synthase
A0W33_RS04145	COG0542	response to heat
A0W33_RS04150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A0W33_RS04165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A0W33_RS04170	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A0W33_RS04175	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A0W33_RS04180	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A0W33_RS04200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A0W33_RS04205	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
A0W33_RS04210	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
A0W33_RS04215	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
A0W33_RS04225	COG2201	protein-glutamate methylesterase activity
A0W33_RS04255	COG0626	cystathionine gamma-synthase activity
A0W33_RS04265	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A0W33_RS04300	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A0W33_RS04305	COG0497	DNA recombination
A0W33_RS04340	COG0037	tRNA processing
A0W33_RS04345	COG0039	L-malate dehydrogenase activity
A0W33_RS04370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A0W33_RS04375	COG1472	Belongs to the glycosyl hydrolase 3 family
A0W33_RS04380	COG0438	transferase activity, transferring glycosyl groups
A0W33_RS04385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A0W33_RS04400	COG0316	Belongs to the HesB IscA family
A0W33_RS04415	COG1668	transmembrane transport
A0W33_RS04420	COG4152	abc transporter atp-binding protein
A0W33_RS04425	COG0484	heat shock protein binding
A0W33_RS04430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A0W33_RS04435	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A0W33_RS04440	COG0563	adenylate kinase activity
A0W33_RS04445	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A0W33_RS04450	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
A0W33_RS04480	COG0596	Alpha beta hydrolase
A0W33_RS04490	COG0277	FAD linked oxidase domain protein
A0W33_RS04495	COG0791	NLP P60 protein
A0W33_RS04520	COG1045	serine acetyltransferase
A0W33_RS04530	COG0477	Major facilitator Superfamily
A0W33_RS04545	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A0W33_RS04550	COG0346	lactoylglutathione lyase activity
A0W33_RS04600	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A0W33_RS04605	COG3591	Belongs to the peptidase S1B family
A0W33_RS04620	COG3525	Glycosyl hydrolase, family 20, catalytic domain
A0W33_RS04640	COG1595	DNA-templated transcription, initiation
A0W33_RS04650	COG0346	lactoylglutathione lyase activity
A0W33_RS04685	COG0783	Belongs to the Dps family
A0W33_RS04690	COG2996	Protein conserved in bacteria
A0W33_RS04700	COG0702	epimerase
A0W33_RS04705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A0W33_RS04730	COG3608	succinylglutamate desuccinylase aspartoacylase
A0W33_RS04740	COG4067	protein conserved in archaea
A0W33_RS04740	COG0189	ligase activity
A0W33_RS04760	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A0W33_RS04765	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A0W33_RS04770	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A0W33_RS04775	COG0835	chemotaxis
A0W33_RS04775	COG0784	Response regulator, receiver
A0W33_RS04785	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A0W33_RS04790	COG0583	DNA-binding transcription factor activity
A0W33_RS04795	COG1418	mRNA catabolic process
A0W33_RS04810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0W33_RS04810	COG0072	phenylalanine-tRNA ligase activity
A0W33_RS04820	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A0W33_RS04830	COG4895	conserved protein (DUF2196)
A0W33_RS04840	COG2003	Belongs to the UPF0758 family
A0W33_RS04890	COG1309	transcriptional regulator
A0W33_RS04895	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS04900	COG2721	sulfolactate sulfo-lyase activity
A0W33_RS04925	COG1073	alpha beta
A0W33_RS04945	COG2755	lipolytic protein G-D-S-L family
A0W33_RS04950	COG2755	lipolytic protein G-D-S-L family
A0W33_RS04975	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A0W33_RS04985	COG1629	transport
A0W33_RS05010	COG0702	epimerase
A0W33_RS05015	COG4771	TonB-dependent receptor
A0W33_RS05020	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
A0W33_RS05025	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS05030	COG1609	Transcriptional regulator
A0W33_RS05035	COG0246	Mannitol dehydrogenase
A0W33_RS05040	COG1904	glucuronate isomerase
A0W33_RS05060	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A0W33_RS05070	COG0745	RESPONSE REGULATOR receiver
A0W33_RS05100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A0W33_RS05125	COG3663	DNA glycosylase
A0W33_RS05140	COG2066	Belongs to the glutaminase family
A0W33_RS05145	COG1132	(ABC) transporter
A0W33_RS05150	COG0612	Peptidase, M16
A0W33_RS05155	COG0612	Peptidase, M16
A0W33_RS05220	COG2204	response regulator
A0W33_RS05225	COG5000	phosphorelay sensor kinase activity
A0W33_RS05230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A0W33_RS05250	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A0W33_RS05255	COG0612	Peptidase, M16
A0W33_RS05290	COG1515	deoxyribonuclease V activity
A0W33_RS05300	COG0542	response to heat
A0W33_RS05330	COG2706	6-phosphogluconolactonase activity
A0W33_RS05350	COG1252	NADH dehydrogenase
A0W33_RS05360	COG0640	Transcriptional regulator
A0W33_RS05370	COG1012	belongs to the aldehyde dehydrogenase family
A0W33_RS05375	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W33_RS05380	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W33_RS05385	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W33_RS05390	COG0649	NAD binding
A0W33_RS05395	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
A0W33_RS05405	COG1034	ATP synthesis coupled electron transport
A0W33_RS05410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A0W33_RS05415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W33_RS05420	COG0839	Belongs to the complex I subunit 6 family
A0W33_RS05430	COG0713	ATP synthesis coupled electron transport
A0W33_RS05435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A0W33_RS05440	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W33_RS05445	COG1007	ATP synthesis coupled electron transport
A0W33_RS05450	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A0W33_RS05475	COG1131	(ABC) transporter
A0W33_RS05505	COG0590	tRNA wobble adenosine to inosine editing
A0W33_RS05510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A0W33_RS05535	COG1253	flavin adenine dinucleotide binding
A0W33_RS05545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A0W33_RS05550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A0W33_RS05565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A0W33_RS05570	COG1619	proteins homologs of microcin C7 resistance protein MccF
A0W33_RS05590	COG3940	Belongs to the glycosyl hydrolase 43 family
A0W33_RS05595	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS05610	COG2312	Erythromycin esterase
A0W33_RS05620	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A0W33_RS05630	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A0W33_RS05635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A0W33_RS05655	COG2885	chlorophyll binding
A0W33_RS05665	COG2885	chlorophyll binding
A0W33_RS05670	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A0W33_RS05675	COG1830	Aldolase
A0W33_RS05680	COG1228	amidohydrolase
A0W33_RS05685	COG0402	S-adenosylhomocysteine deaminase activity
A0W33_RS05710	COG0195	Participates in both transcription termination and antitermination
A0W33_RS05715	COG5180	pathogenesis
A0W33_RS05715	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A0W33_RS05730	COG1970	mechanosensitive ion channel activity
A0W33_RS05735	COG1024	Enoyl-CoA hydratase
A0W33_RS05745	COG0756	dUTP diphosphatase activity
A0W33_RS05770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A0W33_RS05775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A0W33_RS05780	COG0154	amidase activity
A0W33_RS05785	COG0741	lytic transglycosylase activity
A0W33_RS05785	COG1388	LysM domain
A0W33_RS05790	COG0281	malic enzyme
A0W33_RS05790	COG0280	phosphate acetyltransferase
A0W33_RS05795	COG0632	four-way junction helicase activity
A0W33_RS05805	COG0509	glycine decarboxylation via glycine cleavage system
A0W33_RS05815	COG2234	aminopeptidase activity
A0W33_RS05840	COG1561	YicC-like family, N-terminal region
A0W33_RS05845	COG0047	phosphoribosylformylglycinamidine synthase activity
A0W33_RS05850	COG0659	secondary active sulfate transmembrane transporter activity
A0W33_RS05865	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
A0W33_RS05865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0W33_RS05870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0W33_RS05875	COG1183	phosphatidylcholine synthase activity
A0W33_RS05935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A0W33_RS05940	COG0793	Belongs to the peptidase S41A family
A0W33_RS05945	COG0594	ribonuclease P activity
A0W33_RS05990	COG0513	Belongs to the DEAD box helicase family
A0W33_RS06000	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A0W33_RS06015	COG1132	(ABC) transporter
A0W33_RS06025	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A0W33_RS06095	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
A0W33_RS06100	COG0606	chelatase, subunit chli
A0W33_RS06125	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A0W33_RS06135	COG2264	protein methyltransferase activity
A0W33_RS06145	COG0149	triose-phosphate isomerase activity
A0W33_RS06190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A0W33_RS06195	COG2234	aminopeptidase activity
A0W33_RS06205	COG0673	inositol 2-dehydrogenase activity
A0W33_RS06225	COG1530	ribonuclease E activity
A0W33_RS06235	COG0776	regulation of translation
A0W33_RS06245	COG0629	single-stranded DNA binding
A0W33_RS06250	COG4535	Mg2 and Co2 transporter CorC
A0W33_RS06270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A0W33_RS06275	COG1607	acyl-coa hydrolase
A0W33_RS06285	COG1215	transferase activity, transferring glycosyl groups
A0W33_RS06290	COG1960	acyl-CoA dehydrogenase activity
A0W33_RS06300	COG0183	Belongs to the thiolase family
A0W33_RS06305	COG1250	3-hydroxyacyl-CoA dehydrogenase
A0W33_RS06305	COG1024	Enoyl-CoA hydratase
A0W33_RS06310	COG1846	Transcriptional regulator
A0W33_RS06320	COG1022	Amp-dependent synthetase and ligase
A0W33_RS06345	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A0W33_RS06375	COG1160	GTP binding
A0W33_RS06380	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A0W33_RS06385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A0W33_RS06400	COG1104	cysteine desulfurase activity
A0W33_RS06405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A0W33_RS06410	COG3956	TIGRFAM MazG family protein
A0W33_RS06420	COG0811	peptide transport
A0W33_RS06430	COG0848	biopolymer transport protein
A0W33_RS06450	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A0W33_RS06460	COG0564	pseudouridine synthase activity
A0W33_RS06480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A0W33_RS06495	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A0W33_RS06515	COG0512	Glutamine amidotransferase of anthranilate synthase
A0W33_RS06530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A0W33_RS06535	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
A0W33_RS06550	COG0596	Alpha beta hydrolase
A0W33_RS06555	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A0W33_RS06565	COG4771	TonB-dependent receptor
A0W33_RS06575	COG4771	TonB-dependent receptor
A0W33_RS06605	COG4771	TonB-dependent receptor
A0W33_RS06610	COG0697	spore germination
A0W33_RS06615	COG2137	regulation of response to DNA damage stimulus
A0W33_RS06640	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A0W33_RS06660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A0W33_RS06665	COG1476	TRANSCRIPTIONal
A0W33_RS06690	COG0204	Acyl-transferase
A0W33_RS06690	COG0318	PFAM AMP-dependent synthetase and ligase
A0W33_RS06720	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0W33_RS06740	COG0671	phosphoesterase, PA-phosphatase related
A0W33_RS06770	COG2195	Cleaves the N-terminal amino acid of tripeptides
A0W33_RS06775	COG0861	Integral membrane protein TerC family
A0W33_RS06780	COG1666	GTP binding
A0W33_RS06785	COG3040	lipid binding
A0W33_RS06810	COG0300	oxidoreductase activity
A0W33_RS06820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A0W33_RS06850	COG3279	Response regulator of the LytR AlgR family
A0W33_RS06905	COG2205	protein histidine kinase activity
A0W33_RS06905	COG0784	Response regulator, receiver
A0W33_RS06925	COG1573	uracil-dna glycosylase
A0W33_RS06930	COG0436	Aminotransferase
A0W33_RS06935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A0W33_RS06950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A0W33_RS06975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A0W33_RS06985	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A0W33_RS07005	COG5002	protein histidine kinase activity
A0W33_RS07030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A0W33_RS07050	COG0123	including yeast histone deacetylase and acetoin utilization protein
A0W33_RS07070	COG0693	protein deglycase activity
A0W33_RS07085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A0W33_RS07110	COG0791	NLP P60 protein
A0W33_RS07115	COG3339	Conserved Protein
A0W33_RS07135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A0W33_RS07140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A0W33_RS07160	COG3279	Response regulator of the LytR AlgR family
A0W33_RS07165	COG3275	phosphorelay sensor kinase activity
A0W33_RS07175	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A0W33_RS07180	COG1250	3-hydroxyacyl-CoA dehydrogenase
A0W33_RS07200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A0W33_RS07205	COG0601	transmembrane transport
A0W33_RS07220	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A0W33_RS07225	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A0W33_RS07240	COG0156	8-amino-7-oxononanoate synthase activity
A0W33_RS07255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0W33_RS07290	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A0W33_RS07300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0W33_RS07300	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
A0W33_RS07315	COG0386	Belongs to the glutathione peroxidase family
A0W33_RS07330	COG0667	Aldo Keto reductase
A0W33_RS07345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A0W33_RS07350	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
A0W33_RS07360	COG2852	Protein conserved in bacteria
A0W33_RS07365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A0W33_RS07375	COG0552	protein localization to endoplasmic reticulum
A0W33_RS07380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A0W33_RS07385	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A0W33_RS07390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A0W33_RS07405	COG1522	sequence-specific DNA binding
A0W33_RS07410	COG0436	Aminotransferase
A0W33_RS07415	COG4771	TonB-dependent receptor
A0W33_RS07420	COG0671	phosphoesterase, PA-phosphatase related
A0W33_RS07425	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A0W33_RS07425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A0W33_RS07445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A0W33_RS07450	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A0W33_RS07455	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A0W33_RS07460	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A0W33_RS07465	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A0W33_RS07470	COG0356	it plays a direct role in the translocation of protons across the membrane
A0W33_RS07495	COG0322	excinuclease ABC activity
A0W33_RS07515	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A0W33_RS07540	COG0321	lipoyl(octanoyl) transferase activity
A0W33_RS07545	COG2222	sugar isomerase
A0W33_RS07550	COG0792	nuclease activity
A0W33_RS07560	COG0326	Molecular chaperone. Has ATPase activity
A0W33_RS07610	COG1505	serine-type exopeptidase activity
A0W33_RS07625	COG1704	LemA family
A0W33_RS07640	COG0784	Response regulator, receiver
A0W33_RS07640	COG2205	protein histidine kinase activity
A0W33_RS07660	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A0W33_RS07660	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A0W33_RS07675	COG0492	ferredoxin-NADP+ reductase activity
A0W33_RS07695	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A0W33_RS07715	COG0501	Belongs to the peptidase M48B family
A0W33_RS07725	COG0232	Belongs to the dGTPase family. Type 2 subfamily
A0W33_RS07735	COG0612	Peptidase, M16
A0W33_RS07740	COG0612	Peptidase, M16
A0W33_RS07755	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A0W33_RS07775	COG0714	Associated with various cellular activities
A0W33_RS07835	COG3387	PFAM Glycoside hydrolase 15-related
A0W33_RS07875	COG1278	Cold shock
A0W33_RS07880	COG4251	negative regulation of phosphorylation
A0W33_RS07885	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A0W33_RS07900	COG3420	alginic acid biosynthetic process
A0W33_RS07915	COG0671	phosphoesterase, PA-phosphatase related
A0W33_RS07945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A0W33_RS07950	COG0579	oxidoreductase
A0W33_RS07955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A0W33_RS07965	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A0W33_RS07970	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A0W33_RS07975	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A0W33_RS07980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A0W33_RS07980	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A0W33_RS08015	COG0723	plastoquinol--plastocyanin reductase activity
A0W33_RS08070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A0W33_RS08075	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A0W33_RS08115	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A0W33_RS08130	COG0432	Pfam Uncharacterised protein family UPF0047
A0W33_RS08140	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A0W33_RS08165	COG1233	COG1233 Phytoene dehydrogenase and related
A0W33_RS08175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A0W33_RS08180	COG4591	ABC-type transport system involved in lipoprotein release permease component
A0W33_RS08185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A0W33_RS08190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A0W33_RS08200	COG0698	ribose 5-phosphate isomerase
A0W33_RS08205	COG0805	protein transport
A0W33_RS08210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A0W33_RS08225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A0W33_RS08240	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS08245	COG2154	pterin-4-alpha-carbinolamine dehydratase
A0W33_RS08250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A0W33_RS08260	COG0483	inositol monophosphate 1-phosphatase activity
A0W33_RS08275	COG0668	transmembrane transport
A0W33_RS08280	COG0535	radical SAM domain protein
A0W33_RS08295	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A0W33_RS08305	COG5001	Diguanylate cyclase
A0W33_RS08330	COG4221	oxidoreductase activity
A0W33_RS08335	COG2207	Transcriptional regulator
A0W33_RS08335	COG3708	Transcriptional regulator
A0W33_RS08355	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
A0W33_RS08365	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0W33_RS08370	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0W33_RS08380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0W33_RS08380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0W33_RS08425	COG0515	serine threonine protein kinase
A0W33_RS08425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A0W33_RS08435	COG0579	oxidoreductase
A0W33_RS08440	COG1040	competence protein
A0W33_RS08455	COG0708	Exodeoxyribonuclease III
A0W33_RS08470	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A0W33_RS08475	COG0445	tRNA wobble uridine modification
A0W33_RS08490	COG0589	response to stress
A0W33_RS08490	COG0475	glutathione-regulated potassium exporter activity
A0W33_RS08510	COG0423	glycine-tRNA ligase activity
A0W33_RS08515	COG0475	glutathione-regulated potassium exporter activity
A0W33_RS08515	COG0589	response to stress
A0W33_RS08525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A0W33_RS08530	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A0W33_RS08545	COG4172	Belongs to the ABC transporter superfamily
A0W33_RS08550	COG0557	exoribonuclease II activity
A0W33_RS08560	COG0705	Rhomboid family
A0W33_RS08575	COG3273	potassium ion transport
A0W33_RS08575	COG0471	metal ion transport
A0W33_RS08595	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
A0W33_RS08610	COG0189	ligase activity
A0W33_RS08665	COG1607	acyl-coa hydrolase
A0W33_RS08680	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A0W33_RS08685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A0W33_RS08695	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A0W33_RS08700	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A0W33_RS08705	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A0W33_RS08710	COG1187	pseudouridine synthase activity
A0W33_RS08715	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
A0W33_RS08735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A0W33_RS08745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A0W33_RS08745	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A0W33_RS08755	COG3757	hydrolase, family 25
A0W33_RS08760	COG1137	ATPase activity
A0W33_RS08785	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
A0W33_RS08785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A0W33_RS08795	COG0251	oxidation-reduction process
A0W33_RS08800	COG1250	3-hydroxyacyl-CoA dehydrogenase
A0W33_RS08810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A0W33_RS08815	COG0297	glycogen (starch) synthase activity
A0W33_RS08820	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A0W33_RS08825	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
A0W33_RS08835	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A0W33_RS08835	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A0W33_RS08845	COG1960	acyl-CoA dehydrogenase activity
A0W33_RS08855	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A0W33_RS08870	COG0484	heat shock protein binding
A0W33_RS08885	COG0247	lactate metabolic process
A0W33_RS08885	COG2181	nitrate reductase activity
A0W33_RS08890	COG2181	nitrate reductase activity
A0W33_RS08890	COG0247	lactate metabolic process
A0W33_RS08910	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A0W33_RS08930	COG0183	Belongs to the thiolase family
A0W33_RS08940	COG0101	tRNA pseudouridine synthase activity
A0W33_RS08945	COG1132	(ABC) transporter
A0W33_RS08965	COG1132	(ABC) transporter
A0W33_RS08975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A0W33_RS08985	COG0473	3-isopropylmalate dehydrogenase activity
A0W33_RS08995	COG1862	Preprotein translocase
A0W33_RS09005	COG0237	dephospho-CoA kinase activity
A0W33_RS09020	COG0668	transmembrane transport
A0W33_RS09040	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
A0W33_RS09045	COG5002	protein histidine kinase activity
A0W33_RS09055	COG1757	Na H antiporter
A0W33_RS09065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A0W33_RS09075	COG0575	Belongs to the CDS family
A0W33_RS09080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A0W33_RS09085	COG0688	phosphatidylethanolamine metabolic process
A0W33_RS09090	COG1956	GAF domain-containing protein
A0W33_RS09095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A0W33_RS09095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A0W33_RS09100	COG2890	protein-(glutamine-N5) methyltransferase activity
A0W33_RS09105	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A0W33_RS09110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A0W33_RS09120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0W33_RS09125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A0W33_RS09130	COG2226	methyltransferase
A0W33_RS09165	COG4864	UPF0365 protein
A0W33_RS09175	COG0442	prolyl-tRNA aminoacylation
A0W33_RS09195	COG0038	chloride channel
A0W33_RS09225	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS09240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A0W33_RS09250	COG3844	kynureninase activity
A0W33_RS09255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A0W33_RS09255	COG4651	solute:proton antiporter activity
A0W33_RS09270	COG1115	amino acid carrier protein
A0W33_RS09285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A0W33_RS09290	COG3279	Response regulator of the LytR AlgR family
A0W33_RS09295	COG3275	phosphorelay sensor kinase activity
A0W33_RS09320	COG0017	Asparaginyl-tRNA synthetase
A0W33_RS09340	COG1024	Enoyl-CoA hydratase
A0W33_RS09360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A0W33_RS09365	COG1611	Belongs to the LOG family
A0W33_RS09370	COG0577	efflux transmembrane transporter activity
A0W33_RS09370	COG1136	(ABC) transporter
A0W33_RS09375	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A0W33_RS09380	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A0W33_RS09385	COG1121	(ABC) transporter
A0W33_RS09400	COG0488	(ABC) transporter
A0W33_RS09430	COG0596	Alpha beta hydrolase
A0W33_RS09440	COG0242	peptide deformylase activity
A0W33_RS09445	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A0W33_RS09450	COG4771	TonB-dependent receptor
A0W33_RS09470	COG0793	Belongs to the peptidase S41A family
A0W33_RS09475	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
A0W33_RS09500	COG0113	porphobilinogen synthase activity
A0W33_RS09525	COG1254	Belongs to the acylphosphatase family
A0W33_RS09550	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W33_RS09555	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W33_RS09565	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W33_RS09580	COG0649	NAD binding
A0W33_RS09585	COG1139	Iron-sulfur cluster binding protein
A0W33_RS09590	COG2234	aminopeptidase activity
A0W33_RS09595	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A0W33_RS09610	COG1902	pentaerythritol trinitrate reductase activity
A0W33_RS09615	COG0656	L-ascorbic acid biosynthetic process
A0W33_RS09630	COG0612	Peptidase, M16
A0W33_RS09635	COG0022	dehydrogenase e1 component
A0W33_RS09665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A0W33_RS09680	COG2885	chlorophyll binding
A0W33_RS09705	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A0W33_RS09705	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A0W33_RS09745	COG1027	Aspartate ammonia-lyase
A0W33_RS09750	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A0W33_RS09780	COG0477	Major facilitator Superfamily
A0W33_RS09790	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0W33_RS09815	COG1595	DNA-templated transcription, initiation
A0W33_RS09830	COG1136	(ABC) transporter
A0W33_RS09835	COG0577	efflux transmembrane transporter activity
A0W33_RS09835	COG1136	(ABC) transporter
A0W33_RS09840	COG1136	(ABC) transporter
A0W33_RS09840	COG0577	efflux transmembrane transporter activity
A0W33_RS09845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0W33_RS09860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A0W33_RS09865	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A0W33_RS09905	COG2135	peptidase activity
A0W33_RS09945	COG4974	Belongs to the 'phage' integrase family
A0W33_RS09960	COG0772	Belongs to the SEDS family
A0W33_RS09965	COG0768	penicillin binding
A0W33_RS09985	COG0138	bifunctional purine biosynthesis protein purh
A0W33_RS10000	COG0561	phosphatase activity
A0W33_RS10020	COG1278	Cold shock
A0W33_RS10025	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A0W33_RS10040	COG0633	Ferredoxin
A0W33_RS10050	COG0438	transferase activity, transferring glycosyl groups
A0W33_RS10055	COG1138	Cytochrome C-type biogenesis protein
A0W33_RS10080	COG0704	Plays a role in the regulation of phosphate uptake
A0W33_RS10085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A0W33_RS10095	COG0573	inorganic phosphate transmembrane transporter activity
A0W33_RS10100	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A0W33_RS10115	COG1629	transport
A0W33_RS10130	COG0714	Associated with various cellular activities
A0W33_RS10165	COG1381	Involved in DNA repair and RecF pathway recombination
A0W33_RS10170	COG0545	Peptidyl-prolyl cis-trans isomerase
A0W33_RS10180	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A0W33_RS10185	COG0105	UTP biosynthetic process
A0W33_RS10190	COG1652	LysM domain
A0W33_RS10205	COG2267	carboxylic ester hydrolase activity
A0W33_RS10210	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A0W33_RS10215	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A0W33_RS10245	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A0W33_RS10275	COG1132	(ABC) transporter
A0W33_RS10285	COG0513	Belongs to the DEAD box helicase family
A0W33_RS10295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A0W33_RS10350	COG4771	TonB-dependent receptor
A0W33_RS10360	COG0154	amidase activity
A0W33_RS10380	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A0W33_RS10390	COG4974	Belongs to the 'phage' integrase family
A0W33_RS10395	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A0W33_RS10400	COG1960	acyl-CoA dehydrogenase activity
A0W33_RS10410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0W33_RS10420	COG1809	phosphosulfolactate synthase activity
A0W33_RS10430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A0W33_RS10445	COG1595	DNA-templated transcription, initiation
A0W33_RS10475	COG0556	nucleotide-excision repair
A0W33_RS10520	COG2094	Belongs to the DNA glycosylase MPG family
A0W33_RS10550	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A0W33_RS10565	COG0463	Glycosyl transferase, family 2
A0W33_RS10575	COG1595	DNA-templated transcription, initiation
A0W33_RS10580	COG5662	AntiSigma factor
A0W33_RS10585	COG0194	GDP metabolic process
A0W33_RS10590	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A0W33_RS10595	COG0233	cytoplasmic translational termination
A0W33_RS10600	COG0528	UMP kinase activity
A0W33_RS10605	COG0511	ligase activity, forming carbon-carbon bonds
A0W33_RS10610	COG0308	aminopeptidase N
A0W33_RS10650	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A0W33_RS10655	COG0081	regulation of translation
A0W33_RS10660	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A0W33_RS10665	COG0222	ribosome binding
A0W33_RS10670	COG0085	RNA polymerase activity
A0W33_RS10675	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A0W33_RS10685	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A0W33_RS10690	COG0049	tRNA binding
A0W33_RS10695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A0W33_RS10700	COG0051	transcription antitermination factor activity, RNA binding
A0W33_RS10705	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A0W33_RS10710	COG0088	Forms part of the polypeptide exit tunnel
A0W33_RS10715	COG0089	rRNA binding
A0W33_RS10720	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A0W33_RS10725	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A0W33_RS10730	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A0W33_RS10735	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A0W33_RS10740	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A0W33_RS10745	COG0255	Belongs to the universal ribosomal protein uL29 family
A0W33_RS10750	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A0W33_RS10755	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A0W33_RS10760	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A0W33_RS10770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A0W33_RS10775	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A0W33_RS10780	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A0W33_RS10785	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A0W33_RS10790	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A0W33_RS10795	COG1841	ribosomal large subunit assembly
A0W33_RS10800	COG0200	Binds to the 23S rRNA
A0W33_RS10815	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A0W33_RS10820	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A0W33_RS10825	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A0W33_RS10830	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A0W33_RS10835	COG0202	RNA polymerase activity
A0W33_RS10840	COG0203	ribosomal protein L17
A0W33_RS10845	COG0505	Belongs to the CarA family
A0W33_RS10850	COG0148	phosphopyruvate hydratase activity
A0W33_RS10860	COG0443	Heat shock 70 kDa protein
A0W33_RS10890	COG1595	DNA-templated transcription, initiation
A0W33_RS10900	COG0248	Ppx GppA phosphatase
A0W33_RS10910	COG0116	Belongs to the methyltransferase superfamily
A0W33_RS10910	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A0W33_RS10915	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A0W33_RS10930	COG0653	protein targeting
A0W33_RS10935	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A0W33_RS10945	COG1473	amidohydrolase
A0W33_RS10960	COG0071	Belongs to the small heat shock protein (HSP20) family
A0W33_RS10965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A0W33_RS10970	COG1012	belongs to the aldehyde dehydrogenase family
A0W33_RS10975	COG1595	DNA-templated transcription, initiation
A0W33_RS10995	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A0W33_RS11015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A0W33_RS11020	COG0052	Belongs to the universal ribosomal protein uS2 family
A0W33_RS11025	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A0W33_RS11030	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A0W33_RS11045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A0W33_RS11045	COG0604	alcohol dehydrogenase
A0W33_RS11045	COG3321	synthase
A0W33_RS11045	COG4221	oxidoreductase activity
A0W33_RS11050	COG0564	pseudouridine synthase activity
A0W33_RS11055	COG5002	protein histidine kinase activity
A0W33_RS11060	COG0745	RESPONSE REGULATOR receiver
A0W33_RS11070	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A0W33_RS11095	COG0714	Associated with various cellular activities
A0W33_RS11100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A0W33_RS11105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A0W33_RS11110	COG2172	sigma factor antagonist activity
A0W33_RS11115	COG1366	Belongs to the anti-sigma-factor antagonist family
A0W33_RS11125	COG0517	IMP dehydrogenase activity
A0W33_RS11125	COG0516	GMP reductase activity
A0W33_RS11130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A0W33_RS11170	COG2255	four-way junction helicase activity
A0W33_RS11175	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A0W33_RS11200	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A0W33_RS11205	COG1137	ATPase activity
A0W33_RS11230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A0W33_RS11240	COG0569	domain protein
A0W33_RS11245	COG0572	uridine kinase
A0W33_RS11255	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A0W33_RS11260	COG0254	rRNA binding
A0W33_RS11270	COG0470	DNA polymerase III
A0W33_RS11275	COG0181	hydroxymethylbilane synthase activity
A0W33_RS11280	COG1115	amino acid carrier protein
A0W33_RS11295	COG0733	neurotransmitter:sodium symporter activity
A0W33_RS11300	COG1596	polysaccharide export
A0W33_RS11300	COG1555	photosystem II stabilization
A0W33_RS11305	COG2084	Dehydrogenase
A0W33_RS11355	COG1278	Cold shock
A0W33_RS11370	COG1774	PSP1 C-terminal conserved region
A0W33_RS11405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A0W33_RS11410	COG0799	negative regulation of ribosome biogenesis
A0W33_RS11415	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A0W33_RS11415	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A0W33_RS11440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A0W33_RS11450	COG0517	IMP dehydrogenase activity
A0W33_RS11450	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A0W33_RS11455	COG0514	ATP-dependent DNA helicase (RecQ)
A0W33_RS11475	COG3507	Belongs to the glycosyl hydrolase 43 family
A0W33_RS11480	COG3507	Belongs to the glycosyl hydrolase 43 family
A0W33_RS11490	COG4771	TonB-dependent receptor
A0W33_RS11495	COG0702	epimerase
A0W33_RS11510	COG3250	beta-galactosidase activity
A0W33_RS11535	COG1082	Xylose isomerase domain protein TIM barrel
A0W33_RS11560	COG1069	ribulokinase activity
A0W33_RS11575	COG2160	L-arabinose isomerase activity
A0W33_RS11585	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A0W33_RS11590	COG1085	galactose-1-phosphate uridylyltransferase
A0W33_RS11595	COG3507	Belongs to the glycosyl hydrolase 43 family
A0W33_RS11655	COG4191	Histidine kinase
A0W33_RS11685	COG0398	Pfam SNARE associated Golgi protein
A0W33_RS11690	COG0626	cystathionine gamma-synthase activity
A0W33_RS11705	COG1446	asparaginase
A0W33_RS11735	COG3118	belongs to the thioredoxin family
A0W33_RS11750	COG2814	Major facilitator Superfamily
A0W33_RS11755	COG1705	Flagellar rod assembly protein muramidase FlgJ
A0W33_RS11755	COG1388	LysM domain
A0W33_RS11765	COG0612	Peptidase, M16
A0W33_RS11790	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A0W33_RS11795	COG2022	thiamine diphosphate biosynthetic process
A0W33_RS11800	COG0352	thiamine-phosphate diphosphorylase activity
A0W33_RS11805	COG0351	phosphomethylpyrimidine kinase
A0W33_RS11815	COG2104	thiamine diphosphate biosynthetic process
A0W33_RS11820	COG0006	proline dipeptidase activity
A0W33_RS11830	COG0540	Belongs to the ATCase OTCase family
A0W33_RS11835	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A0W33_RS11870	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A0W33_RS11870	COG1796	DNA polymerase
A0W33_RS11875	COG0859	PFAM glycosyl transferase family 9
A0W33_RS11885	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A0W33_RS11890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A0W33_RS11920	COG1090	epimerase
A0W33_RS11925	COG0302	gtp cyclohydrolase
A0W33_RS11950	COG0335	large ribosomal subunit rRNA binding
A0W33_RS11955	COG0336	Belongs to the RNA methyltransferase TrmD family
A0W33_RS11960	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A0W33_RS11965	COG0228	four-way junction DNA binding
A0W33_RS11985	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A0W33_RS11995	COG0860	N-Acetylmuramoyl-L-alanine amidase
A0W33_RS12000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A0W33_RS12005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A0W33_RS12035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A0W33_RS12040	COG1703	isobutyryl-CoA mutase activity
A0W33_RS12065	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A0W33_RS12065	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A0W33_RS12070	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A0W33_RS12080	COG1473	amidohydrolase
A0W33_RS12095	COG0737	Belongs to the 5'-nucleotidase family
A0W33_RS12100	COG0737	Belongs to the 5'-nucleotidase family
A0W33_RS12105	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A0W33_RS12115	COG1764	response to oxidative stress
A0W33_RS12130	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A0W33_RS12150	COG1360	Flagellar Motor Protein
A0W33_RS12155	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A0W33_RS12165	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A0W33_RS12175	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS12195	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A0W33_RS12205	COG5002	protein histidine kinase activity
A0W33_RS12210	COG0745	RESPONSE REGULATOR receiver
A0W33_RS12220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A0W33_RS12245	COG0204	Acyl-transferase
A0W33_RS12245	COG0318	PFAM AMP-dependent synthetase and ligase
A0W33_RS12250	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A0W33_RS12260	COG1136	(ABC) transporter
A0W33_RS12270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A0W33_RS12275	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A0W33_RS12280	COG4771	TonB-dependent receptor
A0W33_RS12290	COG1629	transport
A0W33_RS12305	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A0W33_RS12310	COG0643	Histidine kinase
A0W33_RS12310	COG2198	Histidine kinase
A0W33_RS12310	COG0784	Response regulator, receiver
A0W33_RS12315	COG4251	negative regulation of phosphorylation
A0W33_RS12320	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A0W33_RS12325	COG2045	Belongs to the ComB family
A0W33_RS12330	COG1694	Mazg nucleotide pyrophosphohydrolase
A0W33_RS12335	COG1490	D-aminoacyl-tRNA deacylase activity
A0W33_RS12365	COG0598	Magnesium transport protein CorA
A0W33_RS12380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A0W33_RS12385	COG1216	Glycosyl transferase, family 2
A0W33_RS12425	COG1301	dicarboxylic acid transport
A0W33_RS12430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A0W33_RS12435	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
A0W33_RS12440	COG1162	GTPase activity
A0W33_RS12455	COG0101	tRNA pseudouridine synthase activity
A0W33_RS12460	COG0450	alkyl hydroperoxide reductase
A0W33_RS12470	COG0460	homoserine dehydrogenase
A0W33_RS12470	COG0527	aspartate kinase activity
A0W33_RS12490	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
A0W33_RS12495	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A0W33_RS12500	COG2885	chlorophyll binding
A0W33_RS12505	COG2226	methyltransferase
A0W33_RS12515	COG4221	oxidoreductase activity
A0W33_RS12530	COG1278	Cold shock
A0W33_RS12545	COG3047	cAMP biosynthetic process
A0W33_RS12545	COG2885	chlorophyll binding
A0W33_RS12575	COG1217	gtp-binding protein TYPA
A0W33_RS12580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0W33_RS12600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0W33_RS12600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0W33_RS12615	COG2814	Major facilitator Superfamily
A0W33_RS12620	COG0193	aminoacyl-tRNA hydrolase activity
A0W33_RS12625	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A0W33_RS12630	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A0W33_RS12640	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A0W33_RS12650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A0W33_RS12680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A0W33_RS12685	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A0W33_RS12700	COG0343	queuine tRNA-ribosyltransferase activity
A0W33_RS12720	COG0357	Ribosomal RNA small subunit methyltransferase G
A0W33_RS12725	COG0429	hydrolase of the alpha beta-hydrolase fold
A0W33_RS12735	COG0268	Binds directly to 16S ribosomal RNA
A0W33_RS12750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A0W33_RS12755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A0W33_RS12760	COG0571	ribonuclease III activity
A0W33_RS12775	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A0W33_RS12800	COG0295	cytidine deaminase activity
A0W33_RS12815	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A0W33_RS12820	COG0328	RNA-DNA hybrid ribonuclease activity
A0W33_RS12825	COG2095	MarC family integral membrane protein
A0W33_RS12830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A0W33_RS12835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A0W33_RS12840	COG4974	Belongs to the 'phage' integrase family
A0W33_RS12850	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A0W33_RS12855	COG4771	TonB-dependent receptor
A0W33_RS12875	COG0167	dihydroorotate dehydrogenase activity
A0W33_RS12880	COG1674	ftsk spoiiie
A0W33_RS12900	COG0284	orotidine-5'-phosphate decarboxylase activity
A0W33_RS12910	COG4807	Protein conserved in bacteria
A0W33_RS12930	COG1054	Belongs to the UPF0176 family
A0W33_RS12935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A0W33_RS12945	COG0813	purine-nucleoside phosphorylase activity
A0W33_RS12955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A0W33_RS12965	COG0525	valine-tRNA ligase activity
A0W33_RS12970	COG1404	Belongs to the peptidase S8 family
A0W33_RS12980	COG1629	transport
A0W33_RS13010	COG4206	TonB-dependent receptor
A0W33_RS13090	COG2244	polysaccharide biosynthetic process
A0W33_RS13095	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A0W33_RS13155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A0W33_RS13175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A0W33_RS13175	COG5549	protein import
A0W33_RS13195	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A0W33_RS13210	COG1228	amidohydrolase
A0W33_RS13215	COG1331	Highly conserved protein containing a thioredoxin domain
A0W33_RS13225	COG0359	binds to the 23S rRNA
A0W33_RS13230	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A0W33_RS13235	COG0360	Binds together with S18 to 16S ribosomal RNA
A0W33_RS13245	COG0437	4 iron, 4 sulfur cluster binding
A0W33_RS13275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A0W33_RS13280	COG1612	heme a metabolic process
A0W33_RS13285	COG0109	protoheme IX farnesyltransferase activity
A0W33_RS13290	COG1845	cytochrome c oxidase, subunit III
A0W33_RS13310	COG2322	membrane
A0W33_RS13320	COG5000	phosphorelay sensor kinase activity
A0W33_RS13330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0W33_RS13340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W33_RS13350	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A0W33_RS13355	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A0W33_RS13365	COG0544	peptidyl-prolyl cis-trans isomerase activity
A0W33_RS13375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A0W33_RS13390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A0W33_RS13430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A0W33_RS13445	COG0463	Glycosyl transferase, family 2
A0W33_RS13480	COG4251	negative regulation of phosphorylation
A0W33_RS13490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A0W33_RS13505	COG2814	Major facilitator Superfamily
A0W33_RS13510	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A0W33_RS13515	COG0436	Aminotransferase
A0W33_RS13525	COG2877	3-deoxy-8-phosphooctulonate synthase activity
A0W33_RS13535	COG0463	Glycosyl transferase, family 2
A0W33_RS13545	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A0W33_RS13550	COG1166	arginine decarboxylase activity
A0W33_RS13555	COG0010	Belongs to the arginase family
A0W33_RS13560	COG0018	arginyl-trna synthetase
A0W33_RS13565	COG0386	Belongs to the glutathione peroxidase family
A0W33_RS13570	COG1575	Belongs to the MenA family. Type 1 subfamily
A0W33_RS13585	COG1335	isochorismatase
A0W33_RS13590	COG0513	Belongs to the DEAD box helicase family
A0W33_RS13595	COG0217	transcriptional regulatory protein
A0W33_RS13600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W33_RS13610	COG3186	Phenylalanine-4-hydroxylase
A0W33_RS13630	COG0488	(ABC) transporter
A0W33_RS13645	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A0W33_RS13655	COG0754	glutathionylspermidine amidase activity
A0W33_RS13660	COG0024	Methionine aminopeptidase
A0W33_RS13670	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A0W33_RS13680	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W33_RS13690	COG0713	ATP synthesis coupled electron transport
A0W33_RS13695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A0W33_RS13705	COG1007	ATP synthesis coupled electron transport
A0W33_RS13725	COG1228	amidohydrolase
A0W33_RS13740	COG0753	catalase activity
A0W33_RS13765	COG1070	Carbohydrate kinase
A0W33_RS13790	COG2814	Major facilitator Superfamily
A0W33_RS13800	COG0667	Aldo Keto reductase
A0W33_RS13810	COG1295	ribonuclease BN
A0W33_RS13820	COG2202	Pas domain
A0W33_RS13820	COG1366	Belongs to the anti-sigma-factor antagonist family
A0W33_RS13830	COG0339	signal peptide processing
A0W33_RS13840	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS13880	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
A0W33_RS13885	COG2197	response regulator
A0W33_RS13905	COG1702	phosphate starvation-inducible protein PhoH
A0W33_RS13910	COG2153	protein acetylation
A0W33_RS13915	COG2333	competence protein COMEC
A0W33_RS13915	COG0658	competence protein
A0W33_RS13920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A0W33_RS13930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A0W33_RS13935	COG0300	oxidoreductase activity
A0W33_RS13975	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A0W33_RS13975	COG0321	lipoyl(octanoyl) transferase activity
A0W33_RS13985	COG0784	Response regulator, receiver
A0W33_RS13985	COG2205	protein histidine kinase activity
A0W33_RS13995	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A0W33_RS14010	COG0205	6-phosphofructokinase activity
A0W33_RS14025	COG3273	potassium ion transport
A0W33_RS14025	COG0471	metal ion transport
A0W33_RS14030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A0W33_RS14035	COG5002	protein histidine kinase activity
A0W33_RS14055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0W33_RS14100	COG3340	Belongs to the peptidase S51 family
A0W33_RS14120	COG1595	DNA-templated transcription, initiation
A0W33_RS14125	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A0W33_RS14130	COG2304	oxidoreductase activity
A0W33_RS14135	COG3959	Transketolase, thiamine diphosphate binding domain
A0W33_RS14140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A0W33_RS14145	COG0739	heme binding
A0W33_RS14150	COG0179	Fumarylacetoacetate (FAA) hydrolase
A0W33_RS14170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A0W33_RS14175	COG0305	Participates in initiation and elongation during chromosome replication
A0W33_RS14185	COG1181	Belongs to the D-alanine--D-alanine ligase family
A0W33_RS14200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A0W33_RS14205	COG1404	Belongs to the peptidase S8 family
A0W33_RS14215	COG1011	Hydrolase
A0W33_RS14235	COG1566	PFAM secretion protein HlyD family protein
A0W33_RS14265	COG2723	6-phospho-beta-galactosidase activity
A0W33_RS14275	COG1858	cytochrome C peroxidase
A0W33_RS14280	COG3292	Two component regulator propeller
A0W33_RS14280	COG2205	protein histidine kinase activity
A0W33_RS14280	COG0745	RESPONSE REGULATOR receiver
A0W33_RS14290	COG4124	Belongs to the glycosyl hydrolase 26 family
A0W33_RS14300	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
A0W33_RS14320	COG3345	alpha-galactosidase
A0W33_RS14330	COG4771	TonB-dependent receptor
A0W33_RS14335	COG0561	phosphatase activity
A0W33_RS14350	COG3291	Pkd domain containing protein
A0W33_RS14355	COG1472	Belongs to the glycosyl hydrolase 3 family
A0W33_RS14370	COG0300	oxidoreductase activity
A0W33_RS14385	COG1472	Belongs to the glycosyl hydrolase 3 family
A0W33_RS14405	COG0183	Belongs to the thiolase family
A0W33_RS14425	COG2304	oxidoreductase activity
A0W33_RS14445	COG0598	Magnesium transport protein CorA
A0W33_RS14460	COG0586	Pfam SNARE associated Golgi protein
A0W33_RS14465	COG3158	transport of potassium into the cell
A0W33_RS14470	COG0531	amino acid
A0W33_RS14480	COG0531	amino acid
A0W33_RS14490	COG2271	Major facilitator Superfamily
A0W33_RS14495	COG1301	dicarboxylic acid transport
A0W33_RS14580	COG2855	membrane
A0W33_RS14585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A0W33_RS14600	COG0730	response to heat
A0W33_RS14615	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A0W33_RS14640	COG2816	NAD+ diphosphatase activity
A0W33_RS14645	COG2010	Cytochrome c
A0W33_RS14650	COG1999	signal sequence binding
A0W33_RS14680	COG0187	DNA topoisomerase II activity
A0W33_RS14685	COG1131	(ABC) transporter
A0W33_RS14695	COG1725	Transcriptional regulator
A0W33_RS14715	COG0248	Ppx GppA phosphatase
A0W33_RS14745	COG1640	4-alpha-glucanotransferase
A0W33_RS14765	COG0366	Alpha amylase catalytic
A0W33_RS14770	COG0366	Alpha amylase catalytic
A0W33_RS14775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A0W33_RS14780	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
A0W33_RS14785	COG0668	transmembrane transport
A0W33_RS14795	COG1722	exodeoxyribonuclease VII activity
A0W33_RS14800	COG1570	exodeoxyribonuclease VII activity
A0W33_RS14805	COG2873	o-acetylhomoserine
A0W33_RS14810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A0W33_RS14815	COG0460	homoserine dehydrogenase
A0W33_RS14825	COG0019	diaminopimelate decarboxylase activity
A0W33_RS14830	COG0527	aspartate kinase activity
A0W33_RS14840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A0W33_RS14845	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A0W33_RS14850	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A0W33_RS14855	COG0156	8-amino-7-oxononanoate synthase activity
A0W33_RS14860	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A0W33_RS14890	COG3546	catalase activity
A0W33_RS14930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0W33_RS14945	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A0W33_RS14960	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS14975	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A0W33_RS15000	COG2364	Membrane
A0W33_RS15010	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A0W33_RS15020	COG0730	response to heat
A0W33_RS15030	COG1765	OsmC-like protein
A0W33_RS15040	COG0175	sulfate reduction
A0W33_RS15045	COG0175	sulfate reduction
A0W33_RS15055	COG2133	pyrroloquinoline quinone binding
A0W33_RS15065	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS15090	COG5002	protein histidine kinase activity
A0W33_RS15100	COG0288	reversible hydration of carbon dioxide
A0W33_RS15140	COG1012	belongs to the aldehyde dehydrogenase family
A0W33_RS15145	COG1595	DNA-templated transcription, initiation
A0W33_RS15170	COG1187	pseudouridine synthase activity
A0W33_RS15180	COG0793	Belongs to the peptidase S41A family
A0W33_RS15195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A0W33_RS15220	COG2183	response to ionizing radiation
A0W33_RS15270	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS15275	COG0494	nUDIX hydrolase
A0W33_RS15285	COG1472	Belongs to the glycosyl hydrolase 3 family
A0W33_RS15355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A0W33_RS15365	COG2267	carboxylic ester hydrolase activity
A0W33_RS15420	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
A0W33_RS15425	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A0W33_RS15450	COG0438	transferase activity, transferring glycosyl groups
A0W33_RS15465	COG1696	Membrane protein involved in D-alanine export
A0W33_RS15515	COG0463	Glycosyl transferase, family 2
A0W33_RS15560	COG4191	Histidine kinase
A0W33_RS15565	COG2204	response regulator
A0W33_RS15575	COG0577	efflux transmembrane transporter activity
A0W33_RS15580	COG1136	(ABC) transporter
A0W33_RS15620	COG1981	membrane
A0W33_RS15630	COG3757	hydrolase, family 25
A0W33_RS15640	COG1215	transferase activity, transferring glycosyl groups
A0W33_RS15660	COG3239	Fatty acid desaturase
A0W33_RS15690	COG1510	regulation of RNA biosynthetic process
A0W33_RS15700	COG2195	Cleaves the N-terminal amino acid of tripeptides
A0W33_RS15720	COG3590	peptidase
A0W33_RS15725	COG2267	carboxylic ester hydrolase activity
A0W33_RS15750	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
A0W33_RS15760	COG5002	protein histidine kinase activity
A0W33_RS15835	COG0314	molybdopterin synthase activity
A0W33_RS15850	COG0315	cyclic pyranopterin monophosphate synthase activity
A0W33_RS15850	COG0746	molybdenum cofactor guanylyltransferase activity
A0W33_RS15860	COG0303	'Molybdopterin
A0W33_RS15865	COG2197	response regulator
A0W33_RS15890	COG0405	Gamma-glutamyltransferase
A0W33_RS15905	COG0076	glutamate decarboxylase activity
A0W33_RS15910	COG0488	(ABC) transporter
A0W33_RS15915	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0W33_RS15920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A0W33_RS15935	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
A0W33_RS15970	COG0667	Aldo Keto reductase
A0W33_RS16015	COG5002	protein histidine kinase activity
A0W33_RS16030	COG3409	Peptidoglycan-binding domain 1 protein
A0W33_RS16030	COG0860	N-Acetylmuramoyl-L-alanine amidase
A0W33_RS16070	COG2201	protein-glutamate methylesterase activity
A0W33_RS16075	COG5002	protein histidine kinase activity
A0W33_RS16075	COG2205	protein histidine kinase activity
A0W33_RS16075	COG0784	Response regulator, receiver
A0W33_RS16080	COG0750	zinc metalloprotease
A0W33_RS16135	COG1643	Atp-dependent helicase
A0W33_RS16150	COG2223	nitrite transmembrane transporter activity
A0W33_RS16155	COG1115	amino acid carrier protein
A0W33_RS16160	COG0784	Response regulator, receiver
A0W33_RS16160	COG5002	protein histidine kinase activity
A0W33_RS16160	COG2198	Histidine kinase
A0W33_RS16180	COG1007	ATP synthesis coupled electron transport
A0W33_RS16190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A0W33_RS16195	COG0713	ATP synthesis coupled electron transport
A0W33_RS16205	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W33_RS16210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A0W33_RS16225	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
A0W33_RS16235	COG0649	NAD binding
A0W33_RS16235	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W33_RS16245	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W33_RS16250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W33_RS16255	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A0W33_RS16280	COG0702	epimerase
A0W33_RS16295	COG3665	Urea carboxylase-associated protein
A0W33_RS16310	COG0583	DNA-binding transcription factor activity
A0W33_RS16335	COG4974	Belongs to the 'phage' integrase family
A0W33_RS16410	COG0577	efflux transmembrane transporter activity
A0W33_RS16425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A0W33_RS16430	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A0W33_RS16470	COG3852	Histidine kinase
A0W33_RS16475	COG0402	S-adenosylhomocysteine deaminase activity
A0W33_RS16480	COG0501	Belongs to the peptidase M48B family
A0W33_RS16525	COG4251	negative regulation of phosphorylation
A0W33_RS16535	COG2353	YceI-like domain
A0W33_RS16550	COG2814	Major facilitator Superfamily
A0W33_RS16560	COG0513	Belongs to the DEAD box helicase family
A0W33_RS16565	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A0W33_RS16590	COG0529	Catalyzes the synthesis of activated sulfate
A0W33_RS16605	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A0W33_RS16620	COG3537	Alpha-1,2-mannosidase
A0W33_RS16640	COG1289	transmembrane transporter activity
A0W33_RS16675	COG1335	isochorismatase
A0W33_RS16690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A0W33_RS16700	COG0671	phosphoesterase, PA-phosphatase related
A0W33_RS16705	COG0745	RESPONSE REGULATOR receiver
A0W33_RS16710	COG0642	Histidine kinase
A0W33_RS16745	COG1187	pseudouridine synthase activity
A0W33_RS16750	COG5002	protein histidine kinase activity
A0W33_RS16760	COG2169	Transcriptional regulator
A0W33_RS16775	COG1131	(ABC) transporter
A0W33_RS16830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A0W33_RS16835	COG1253	flavin adenine dinucleotide binding
A0W33_RS16850	COG3237	CsbD-like
A0W33_RS16875	COG3781	membrane
A0W33_RS16915	COG4251	negative regulation of phosphorylation
A0W33_RS16985	COG3546	catalase activity
A0W33_RS16995	COG0415	Belongs to the DNA photolyase family
A0W33_RS17000	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS17005	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A0W33_RS17020	COG2086	electron transfer activity
A0W33_RS17025	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A0W33_RS17035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A0W33_RS17045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A0W33_RS17050	COG0300	oxidoreductase activity
A0W33_RS17055	COG1131	(ABC) transporter
A0W33_RS17095	COG0717	Belongs to the dCTP deaminase family
A0W33_RS17100	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A0W33_RS17110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A0W33_RS17110	COG0519	Catalyzes the synthesis of GMP from XMP
A0W33_RS17120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A0W33_RS17130	COG2884	Cell division ATP-binding protein ftsE
A0W33_RS17160	COG2089	acid synthase
A0W33_RS17170	COG3980	spore coat polysaccharide biosynthesis protein
A0W33_RS17175	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
A0W33_RS17180	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS17190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A0W33_RS17195	COG1086	Polysaccharide biosynthesis protein
A0W33_RS17205	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A0W33_RS17210	COG0590	tRNA wobble adenosine to inosine editing
A0W33_RS17235	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A0W33_RS17240	COG0583	DNA-binding transcription factor activity
A0W33_RS17260	COG1295	ribonuclease BN
A0W33_RS17270	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A0W33_RS17275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A0W33_RS17280	COG0116	Belongs to the methyltransferase superfamily
A0W33_RS17300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A0W33_RS17310	COG0210	DNA helicase
A0W33_RS17340	COG0439	Biotin carboxylase
A0W33_RS17345	COG0511	ligase activity, forming carbon-carbon bonds
A0W33_RS17350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A0W33_RS17360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A0W33_RS17370	COG1629	transport
A0W33_RS17375	COG0823	Involved in the tonB-independent uptake of proteins
A0W33_RS17375	COG4946	Tricorn protease homolog
A0W33_RS17375	COG1506	peptidase
A0W33_RS17410	COG0534	Mate efflux family protein
A0W33_RS17420	COG2731	YhcH YjgK YiaL family protein
A0W33_RS17425	COG1193	negative regulation of DNA recombination
A0W33_RS17445	COG1754	DNA topoisomerase type I activity
A0W33_RS17445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A0W33_RS17460	COG0840	transmembrane signaling receptor activity
A0W33_RS17465	COG0835	chemotaxis
A0W33_RS17470	COG2201	protein-glutamate methylesterase activity
A0W33_RS17475	COG2201	protein-glutamate methylesterase activity
A0W33_RS17480	COG2198	Histidine kinase
A0W33_RS17480	COG0643	Histidine kinase
A0W33_RS17485	COG1776	CheC inhibitor of MCP methylation
A0W33_RS17495	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A0W33_RS17500	COG0010	Belongs to the arginase family
A0W33_RS17505	COG1950	PFAM Membrane protein of
A0W33_RS17515	COG0514	ATP-dependent DNA helicase (RecQ)
A0W33_RS17530	COG1741	Belongs to the pirin family
A0W33_RS17540	COG2204	response regulator
A0W33_RS17545	COG3852	Histidine kinase
A0W33_RS17560	COG2824	Alkylphosphonate utilization operon protein PhnA
A0W33_RS17590	COG0166	Belongs to the GPI family
A0W33_RS17595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A0W33_RS17605	COG0191	fructose-bisphosphate aldolase activity
A0W33_RS17610	COG0577	efflux transmembrane transporter activity
A0W33_RS17610	COG1136	(ABC) transporter
A0W33_RS17615	COG1199	ATP-dependent helicase activity
A0W33_RS17615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A0W33_RS17620	COG0628	permease
A0W33_RS17645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A0W33_RS17650	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A0W33_RS17655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A0W33_RS17660	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A0W33_RS17665	COG2130	NADP-dependent
A0W33_RS17670	COG1979	alcohol dehydrogenase
A0W33_RS17675	COG1309	transcriptional regulator
A0W33_RS17710	COG0346	lactoylglutathione lyase activity
A0W33_RS17720	COG0798	PFAM Bile acid sodium symporter
A0W33_RS17730	COG0668	transmembrane transport
A0W33_RS17735	COG0366	Alpha amylase catalytic
A0W33_RS17740	COG0596	Alpha beta hydrolase
A0W33_RS17755	COG1845	cytochrome c oxidase, subunit III
A0W33_RS17805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A0W33_RS17815	COG0545	Peptidyl-prolyl cis-trans isomerase
A0W33_RS17820	COG0069	glutamate synthase activity
A0W33_RS17825	COG1703	isobutyryl-CoA mutase activity
A0W33_RS17825	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A0W33_RS17825	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A0W33_RS17835	COG0481	GTPase activity
A0W33_RS17840	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A0W33_RS17845	COG1064	alcohol dehydrogenase
A0W33_RS17850	COG0602	queuosine metabolic process
A0W33_RS17880	COG0667	Aldo Keto reductase
A0W33_RS17885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A0W33_RS17900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A0W33_RS17900	COG0189	ligase activity
A0W33_RS17915	COG1045	serine acetyltransferase
A0W33_RS17920	COG1940	carbohydrate kinase activity
A0W33_RS17925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A0W33_RS17930	COG0698	ribose 5-phosphate isomerase
A0W33_RS17935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A0W33_RS17940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A0W33_RS17945	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A0W33_RS17950	COG0363	glucosamine-6-phosphate deaminase activity
A0W33_RS17955	COG0604	alcohol dehydrogenase
A0W33_RS17955	COG3321	synthase
A0W33_RS17955	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS17960	COG2354	Protein conserved in bacteria
A0W33_RS17965	COG2226	methyltransferase
A0W33_RS17980	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A0W33_RS17985	COG2321	neutral zinc metallopeptidase
A0W33_RS17990	COG0667	Aldo Keto reductase
A0W33_RS17995	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A0W33_RS18015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A0W33_RS18025	COG2171	N-acyltransferase activity
A0W33_RS18030	COG1250	3-hydroxyacyl-CoA dehydrogenase
A0W33_RS18040	COG0488	(ABC) transporter
A0W33_RS18080	COG0501	Belongs to the peptidase M48B family
A0W33_RS18100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A0W33_RS18110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A0W33_RS18115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A0W33_RS18125	COG0501	Belongs to the peptidase M48B family
A0W33_RS18130	COG0612	Peptidase, M16
A0W33_RS18145	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A0W33_RS18165	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A0W33_RS18170	COG0494	nUDIX hydrolase
A0W33_RS18175	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A0W33_RS18205	COG2363	Small membrane protein
A0W33_RS18215	COG0584	glycerophosphoryl diester phosphodiesterase
A0W33_RS18225	COG2304	oxidoreductase activity
A0W33_RS18245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0W33_RS18250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0W33_RS18260	COG0534	Mate efflux family protein
A0W33_RS18265	COG0436	Aminotransferase
A0W33_RS18270	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
A0W33_RS18290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A0W33_RS18300	COG3457	Alanine racemase
A0W33_RS18315	COG0038	chloride channel
A0W33_RS18320	COG0750	zinc metalloprotease
A0W33_RS18340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A0W33_RS18350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A0W33_RS18355	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A0W33_RS18360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A0W33_RS18365	COG0165	Argininosuccinate lyase
A0W33_RS18380	COG0189	ligase activity
A0W33_RS18380	COG0569	domain protein
A0W33_RS18400	COG0484	heat shock protein binding
A0W33_RS18430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A0W33_RS18435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A0W33_RS18440	COG1966	Carbon starvation protein
A0W33_RS18445	COG0758	DNA mediated transformation
A0W33_RS18455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A0W33_RS18460	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A0W33_RS18465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A0W33_RS18480	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A0W33_RS18515	COG4771	TonB-dependent receptor
A0W33_RS18520	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A0W33_RS18530	COG0436	Aminotransferase
A0W33_RS18545	COG0513	Belongs to the DEAD box helicase family
A0W33_RS18550	COG0628	permease
A0W33_RS18605	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A0W33_RS18630	COG0667	Aldo Keto reductase
A0W33_RS18655	COG4251	negative regulation of phosphorylation
A0W33_RS18660	COG1074	ATP-dependent DNA helicase activity
A0W33_RS18670	COG0513	Belongs to the DEAD box helicase family
A0W33_RS18680	COG2081	HI0933 family
A0W33_RS18695	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS18720	COG1309	transcriptional regulator
A0W33_RS18730	COG3339	Conserved Protein
A0W33_RS18745	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A0W33_RS18760	COG1446	asparaginase
A0W33_RS18770	COG3685	Protein conserved in bacteria
A0W33_RS18775	COG0308	aminopeptidase N
A0W33_RS18805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A0W33_RS18820	COG0671	phosphoesterase, PA-phosphatase related
A0W33_RS18825	COG0408	coproporphyrinogen oxidase activity
A0W33_RS18840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A0W33_RS18870	COG4181	ATPase activity
A0W33_RS18880	COG4221	oxidoreductase activity
A0W33_RS18890	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A0W33_RS18900	COG1760	l-serine dehydratase
A0W33_RS18915	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A0W33_RS18930	COG2816	NAD+ diphosphatase activity
A0W33_RS18935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A0W33_RS18935	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A0W33_RS18940	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A0W33_RS18945	COG0424	maF-like protein
A0W33_RS18955	COG0259	pyridoxamine-phosphate oxidase activity
A0W33_RS18960	COG1678	Uncharacterized ACR, COG1678
A0W33_RS19000	COG1028	Short-chain dehydrogenase reductase Sdr
A0W33_RS19035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0W33_RS19040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A0W33_RS19050	COG0300	oxidoreductase activity
A0W33_RS19055	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A0W33_RS19065	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
A0W33_RS19070	COG2409	Drug exporters of the RND superfamily
A0W33_RS19090	COG0673	inositol 2-dehydrogenase activity
A0W33_RS19095	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
A0W33_RS19115	COG0495	leucyl-tRNA aminoacylation
A0W33_RS19125	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A0W33_RS19130	COG0655	NAD(P)H dehydrogenase (quinone) activity
A0W33_RS19140	COG1368	sulfuric ester hydrolase activity
A0W33_RS19145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A0W33_RS19160	COG0577	efflux transmembrane transporter activity
A0W33_RS19180	COG1663	tetraacyldisaccharide 4'-kinase activity
A0W33_RS19185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A0W33_RS19200	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A0W33_RS19205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A0W33_RS19210	COG3604	Transcriptional regulator
A0W33_RS19230	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A0W33_RS19235	COG0459	protein refolding
A0W33_RS19250	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
A0W33_RS19255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A0W33_RS19275	COG1196	nuclear chromosome segregation
A0W33_RS19290	COG1752	Esterase of the alpha-beta hydrolase superfamily
A0W33_RS19295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0W33_RS19300	COG0825	malonyl-CoA metabolic process
A0W33_RS19310	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
A0W33_RS19315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0W33_RS19340	COG1418	mRNA catabolic process
A0W33_RS19355	COG0427	acetyl-CoA hydrolase
A0W33_RS19370	COG2204	response regulator
A0W33_RS19375	COG2205	protein histidine kinase activity
A0W33_RS19375	COG0784	Response regulator, receiver
A0W33_RS19380	COG1473	amidohydrolase
A0W33_RS19385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A0W33_RS19390	COG0596	Alpha beta hydrolase
A0W33_RS19395	COG0140	phosphoribosyl-ATP diphosphatase activity
A0W33_RS19395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A0W33_RS19400	COG0107	imidazoleglycerol-phosphate synthase activity
A0W33_RS19405	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A0W33_RS19410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A0W33_RS19415	COG2239	Acts as a magnesium transporter
A0W33_RS19425	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A0W33_RS19430	COG0159	tryptophan synthase activity
A0W33_RS19435	COG0133	tryptophan synthase activity
A0W33_RS19440	COG0135	phosphoribosylanthranilate isomerase activity
A0W33_RS19445	COG0134	indole-3-glycerol-phosphate synthase activity
A0W33_RS19450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A0W33_RS19455	COG0512	Glutamine amidotransferase of anthranilate synthase
A0W33_RS19470	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A0W33_RS19470	COG0131	Imidazoleglycerol-phosphate dehydratase
A0W33_RS19475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A0W33_RS19480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A0W33_RS19485	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A0W33_RS19515	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A0W33_RS19530	COG0482	sulfurtransferase activity
A0W33_RS19535	COG0135	phosphoribosylanthranilate isomerase activity
A0W33_RS19540	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A0W33_RS19555	COG0848	biopolymer transport protein
A0W33_RS19560	COG0811	peptide transport
A0W33_RS19595	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A0W33_RS19605	COG0156	8-amino-7-oxononanoate synthase activity
A0W33_RS19610	COG0439	Biotin carboxylase
A0W33_RS19620	COG0739	heme binding
A0W33_RS19625	COG0492	ferredoxin-NADP+ reductase activity
A0W33_RS19630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A0W33_RS19635	COG1185	polyribonucleotide nucleotidyltransferase activity
A0W33_RS19640	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A0W33_RS19660	COG2304	oxidoreductase activity
A0W33_RS19675	COG0366	Alpha amylase catalytic
A0W33_RS19680	COG0488	(ABC) transporter
A0W33_RS19690	COG0753	catalase activity
A0W33_RS19700	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A0W33_RS19710	COG0504	CTP synthase activity
A0W33_RS19715	COG0706	membrane insertase activity
A0W33_RS19730	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
A0W33_RS19740	COG4166	transmembrane transport
A0W33_RS19745	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A0W33_RS19750	COG1192	Involved in chromosome partitioning
A0W33_RS19755	COG1475	DNA binding
A0W33_RS19765	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A0W33_RS19775	COG1393	Belongs to the ArsC family
A0W33_RS19790	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A0W33_RS19805	COG2877	3-deoxy-8-phosphooctulonate synthase activity
A0W33_RS19835	COG0539	negative regulation of cytoplasmic translation
A0W33_RS19845	COG0791	NLP P60 protein
A0W33_RS19850	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A0W33_RS19860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A0W33_RS19870	COG2177	Part of the ABC transporter FtsEX involved in
A0W33_RS19880	COG1968	undecaprenyl-diphosphatase activity
A0W33_RS19885	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A0W33_RS19890	COG0196	riboflavin kinase activity
A0W33_RS19900	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A0W33_RS19910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A0W33_RS19910	COG3153	acetyltransferase
A0W33_RS19935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A0W33_RS19940	COG0438	transferase activity, transferring glycosyl groups
A0W33_RS19960	COG0482	sulfurtransferase activity
A0W33_RS19975	COG0438	transferase activity, transferring glycosyl groups
A0W33_RS20005	COG0124	histidyl-tRNA synthetase
A0W33_RS20015	COG0124	histidyl-tRNA synthetase
A0W33_RS20280	COG0747	negative chemotaxis
A0W33_RS20520	COG0348	domain, Protein