locus-tag	class	description
CS550_RS00015	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CS550_RS00020	COG0049	tRNA binding
CS550_RS00025	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CS550_RS00030	COG0051	transcription antitermination factor activity, RNA binding
CS550_RS00035	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CS550_RS00040	COG0088	Forms part of the polypeptide exit tunnel
CS550_RS00045	COG0089	rRNA binding
CS550_RS00050	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CS550_RS00055	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CS550_RS00060	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CS550_RS00065	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CS550_RS00070	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CS550_RS00075	COG0255	Belongs to the universal ribosomal protein uL29 family
CS550_RS00080	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CS550_RS00085	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CS550_RS00090	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CS550_RS00095	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CS550_RS00100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CS550_RS00105	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CS550_RS00110	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CS550_RS00115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CS550_RS00120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CS550_RS00125	COG1841	ribosomal large subunit assembly
CS550_RS00130	COG0200	Binds to the 23S rRNA
CS550_RS00135	COG0201	protein transport
CS550_RS00145	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CS550_RS00150	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CS550_RS00155	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CS550_RS00160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CS550_RS00165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CS550_RS00170	COG0202	RNA polymerase activity
CS550_RS00175	COG0203	ribosomal protein L17
CS550_RS00200	COG0528	UMP kinase activity
CS550_RS00205	COG0233	cytoplasmic translational termination
CS550_RS00210	COG1162	GTPase activity
CS550_RS00230	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CS550_RS00260	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CS550_RS00265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CS550_RS00270	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CS550_RS00285	COG1216	Glycosyl transferase, family 2
CS550_RS00285	COG0463	Glycosyl transferase, family 2
CS550_RS00290	COG1752	Esterase of the alpha-beta hydrolase superfamily
CS550_RS00295	COG0215	cysteine-tRNA ligase activity
CS550_RS00300	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CS550_RS00315	COG0792	nuclease activity
CS550_RS00330	COG1755	Isoprenylcysteine carboxyl methyltransferase
CS550_RS00360	COG1929	Belongs to the glycerate kinase type-1 family
CS550_RS00365	COG0716	FMN binding
CS550_RS00385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CS550_RS00395	COG2176	DNA-directed DNA polymerase activity
CS550_RS00395	COG5002	protein histidine kinase activity
CS550_RS00410	COG0497	DNA recombination
CS550_RS00415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CS550_RS00420	COG0251	oxidation-reduction process
CS550_RS00440	COG0339	signal peptide processing
CS550_RS00455	COG0475	glutathione-regulated potassium exporter activity
CS550_RS00460	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CS550_RS00465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CS550_RS00465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CS550_RS00505	COG1269	ATP hydrolysis coupled proton transport
CS550_RS00545	COG0358	DNA primase activity
CS550_RS00550	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CS550_RS00555	COG2249	NAD(P)H dehydrogenase (quinone) activity
CS550_RS00560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CS550_RS00570	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CS550_RS00575	COG3005	denitrification pathway
CS550_RS00590	COG0148	phosphopyruvate hydratase activity
CS550_RS00610	COG1022	Amp-dependent synthetase and ligase
CS550_RS00615	COG0514	ATP-dependent DNA helicase (RecQ)
CS550_RS00630	COG0297	glycogen (starch) synthase activity
CS550_RS00640	COG2211	Major facilitator Superfamily
CS550_RS00645	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CS550_RS00715	COG0156	8-amino-7-oxononanoate synthase activity
CS550_RS00720	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CS550_RS00730	COG2151	metal-sulfur cluster biosynthetic enzyme
CS550_RS00735	COG0484	heat shock protein binding
CS550_RS00740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CS550_RS00745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CS550_RS00750	COG0671	phosphoesterase, PA-phosphatase related
CS550_RS00755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CS550_RS00760	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CS550_RS00780	COG0606	chelatase, subunit chli
CS550_RS00790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CS550_RS00795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CS550_RS00800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CS550_RS00805	COG0571	ribonuclease III activity
CS550_RS00810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CS550_RS00820	COG1121	(ABC) transporter
CS550_RS00835	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CS550_RS00850	COG3588	fructose-bisphosphate aldolase
CS550_RS00855	COG0823	Involved in the tonB-independent uptake of proteins
CS550_RS00855	COG1506	peptidase
CS550_RS00860	COG0709	Synthesizes selenophosphate from selenide and ATP
CS550_RS00880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CS550_RS00885	COG0698	ribose 5-phosphate isomerase
CS550_RS00895	COG0281	malic enzyme
CS550_RS00895	COG0280	phosphate acetyltransferase
CS550_RS00905	COG0577	efflux transmembrane transporter activity
CS550_RS00910	COG1136	(ABC) transporter
CS550_RS00915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS550_RS00935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CS550_RS00955	COG2059	Chromate
CS550_RS01010	COG2878	Part of a membrane complex involved in electron transport
CS550_RS01010	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS550_RS01015	COG4656	Part of a membrane complex involved in electron transport
CS550_RS01020	COG4658	electron transport chain
CS550_RS01025	COG4659	FMN binding
CS550_RS01030	COG4660	Part of a membrane complex involved in electron transport
CS550_RS01035	COG4657	Part of a membrane complex involved in electron transport
CS550_RS01045	COG1477	protein flavinylation
CS550_RS01055	COG0463	Glycosyl transferase, family 2
CS550_RS01070	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CS550_RS01075	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CS550_RS01080	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CS550_RS01100	COG1703	isobutyryl-CoA mutase activity
CS550_RS01115	COG2986	histidine ammonia-lyase
CS550_RS01120	COG3404	Formiminotransferase-cyclodeaminase
CS550_RS01135	COG1228	amidohydrolase
CS550_RS01165	COG0463	Glycosyl transferase, family 2
CS550_RS01170	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CS550_RS01195	COG0626	cystathionine gamma-synthase activity
CS550_RS01210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CS550_RS01215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CS550_RS01220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CS550_RS01265	COG0540	Belongs to the ATCase OTCase family
CS550_RS01270	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CS550_RS01275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CS550_RS01280	COG1704	LemA family
CS550_RS01300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CS550_RS01320	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CS550_RS01335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CS550_RS01340	COG0052	Belongs to the universal ribosomal protein uS2 family
CS550_RS01345	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CS550_RS01350	COG0556	nucleotide-excision repair
CS550_RS01355	COG3263	regulation of cellular component size
CS550_RS01365	COG0750	zinc metalloprotease
CS550_RS01375	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CS550_RS01380	COG4974	Belongs to the 'phage' integrase family
CS550_RS01395	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CS550_RS01415	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CS550_RS01420	COG0081	regulation of translation
CS550_RS01425	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CS550_RS01430	COG0222	ribosome binding
CS550_RS01435	COG0085	RNA polymerase activity
CS550_RS01440	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CS550_RS01445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CS550_RS01455	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CS550_RS01465	COG1774	PSP1 C-terminal conserved region
CS550_RS01470	COG1418	mRNA catabolic process
CS550_RS01505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CS550_RS01510	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CS550_RS01525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS550_RS01530	COG0514	ATP-dependent DNA helicase (RecQ)
CS550_RS01535	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CS550_RS01540	COG0740	serine-type endopeptidase activity
CS550_RS01635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CS550_RS01635	COG0674	pyruvate-flavodoxin oxidoreductase activity
CS550_RS01640	COG1013	pyruvate-flavodoxin oxidoreductase activity
CS550_RS01650	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CS550_RS01660	COG4464	protein tyrosine phosphatase activity
CS550_RS01665	COG3206	protein involved in exopolysaccharide biosynthesis
CS550_RS01665	COG0489	protein tyrosine kinase activity
CS550_RS01705	COG2195	Cleaves the N-terminal amino acid of tripeptides
CS550_RS01710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CS550_RS01715	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CS550_RS01735	COG1253	flavin adenine dinucleotide binding
CS550_RS01770	COG5433	transposase activity
CS550_RS01775	COG4974	Belongs to the 'phage' integrase family
CS550_RS01805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CS550_RS01805	COG2207	Transcriptional regulator
CS550_RS01810	COG0534	Mate efflux family protein
CS550_RS01885	COG0285	dihydrofolate synthase activity
CS550_RS01890	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CS550_RS01895	COG0735	belongs to the Fur family
CS550_RS01905	COG1482	cell wall glycoprotein biosynthetic process
CS550_RS01920	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CS550_RS01935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CS550_RS01945	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CS550_RS01960	COG0156	8-amino-7-oxononanoate synthase activity
CS550_RS01970	COG0237	dephospho-CoA kinase activity
CS550_RS01980	COG1862	Preprotein translocase
CS550_RS01985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CS550_RS01995	COG2255	four-way junction helicase activity
CS550_RS02010	COG3591	Belongs to the peptidase S1B family
CS550_RS02035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CS550_RS02040	COG1854	S-ribosylhomocysteine lyase activity
CS550_RS02050	COG0343	queuine tRNA-ribosyltransferase activity
CS550_RS02060	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CS550_RS02065	COG1506	peptidase
CS550_RS02065	COG0823	Involved in the tonB-independent uptake of proteins
CS550_RS02070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CS550_RS02075	COG2957	Belongs to the agmatine deiminase family
CS550_RS02095	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CS550_RS02100	COG2715	membrane protein required for spore maturation
CS550_RS02105	COG0194	GDP metabolic process
CS550_RS02115	COG0653	protein targeting
CS550_RS02130	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CS550_RS02145	COG0459	protein refolding
CS550_RS02150	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CS550_RS02155	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CS550_RS02170	COG0504	CTP synthase activity
CS550_RS02175	COG0706	membrane insertase activity
CS550_RS02185	COG0505	Belongs to the CarA family
CS550_RS02190	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CS550_RS02195	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CS550_RS02195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CS550_RS02200	COG2720	vancomycin resistance protein
CS550_RS02245	COG2195	Cleaves the N-terminal amino acid of tripeptides
CS550_RS02275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CS550_RS02335	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CS550_RS02340	COG0402	S-adenosylhomocysteine deaminase activity
CS550_RS02345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CS550_RS02350	COG2985	domain, Protein
CS550_RS02350	COG0569	domain protein
CS550_RS02365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CS550_RS02375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CS550_RS02380	COG0275	rRNA processing
CS550_RS02390	COG0768	penicillin binding
CS550_RS02395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CS550_RS02400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CS550_RS02405	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CS550_RS02410	COG0772	Belongs to the SEDS family
CS550_RS02415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CS550_RS02420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CS550_RS02430	COG0849	cell division
CS550_RS02435	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CS550_RS02450	COG2860	membrane
CS550_RS02455	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CS550_RS02460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CS550_RS02460	COG0519	Catalyzes the synthesis of GMP from XMP
CS550_RS02465	COG0254	rRNA binding
CS550_RS02470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CS550_RS02475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CS550_RS02480	COG0360	Binds together with S18 to 16S ribosomal RNA
CS550_RS02485	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CS550_RS02490	COG0359	binds to the 23S rRNA
CS550_RS02500	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CS550_RS02500	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CS550_RS02515	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CS550_RS02520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CS550_RS02555	COG1217	gtp-binding protein TYPA
CS550_RS02570	COG3634	alkyl hydroperoxide reductase activity
CS550_RS02575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CS550_RS02590	COG0149	triose-phosphate isomerase activity
CS550_RS02600	COG0302	gtp cyclohydrolase
CS550_RS02615	COG0724	RNA recognition motif
CS550_RS02625	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CS550_RS02630	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CS550_RS02635	COG0811	peptide transport
CS550_RS02650	COG0693	protein deglycase activity
CS550_RS02655	COG2264	protein methyltransferase activity
CS550_RS02660	COG0534	Mate efflux family protein
CS550_RS02665	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CS550_RS02670	COG1663	tetraacyldisaccharide 4'-kinase activity
CS550_RS02675	COG0616	signal peptide processing
CS550_RS02690	COG1120	ATPase activity
CS550_RS02695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CS550_RS02730	COG0560	Phosphoserine phosphatase
CS550_RS02730	COG3830	Belongs to the UPF0237 family
CS550_RS02740	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CS550_RS02745	COG0424	maF-like protein
CS550_RS02750	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CS550_RS02775	COG0673	inositol 2-dehydrogenase activity
CS550_RS02780	COG3250	beta-galactosidase activity
CS550_RS02790	COG4771	TonB-dependent receptor
CS550_RS02795	COG4822	anaerobic cobalamin biosynthetic process
CS550_RS02810	COG1120	ATPase activity
CS550_RS02825	COG4221	oxidoreductase activity
CS550_RS02870	COG1136	(ABC) transporter
CS550_RS02880	COG1012	belongs to the aldehyde dehydrogenase family
CS550_RS02885	COG1454	alcohol dehydrogenase
CS550_RS02890	COG0427	acetyl-CoA hydrolase
CS550_RS02905	COG2885	chlorophyll binding
CS550_RS02910	COG2885	chlorophyll binding
CS550_RS02940	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CS550_RS02945	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CS550_RS02950	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CS550_RS02960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CS550_RS02970	COG4771	TonB-dependent receptor
CS550_RS02980	COG0545	Peptidyl-prolyl cis-trans isomerase
CS550_RS02985	COG0545	Peptidyl-prolyl cis-trans isomerase
CS550_RS02995	COG0512	Glutamine amidotransferase of anthranilate synthase
CS550_RS03000	COG3142	Participates in the control of copper homeostasis
CS550_RS03025	COG5002	protein histidine kinase activity
CS550_RS03030	COG0745	RESPONSE REGULATOR receiver
CS550_RS03035	COG0791	NLP P60 protein
CS550_RS03040	COG1506	peptidase
CS550_RS03040	COG0823	Involved in the tonB-independent uptake of proteins
CS550_RS03045	COG1011	Hydrolase
CS550_RS03065	COG1181	Belongs to the D-alanine--D-alanine ligase family
CS550_RS03070	COG0564	pseudouridine synthase activity
CS550_RS03095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CS550_RS03100	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CS550_RS03115	COG1234	tRNA 3'-trailer cleavage
CS550_RS03125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CS550_RS03135	COG4191	Histidine kinase
CS550_RS03140	COG2204	response regulator
CS550_RS03155	COG1216	Glycosyl transferase, family 2
CS550_RS03165	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CS550_RS03170	COG0826	peptidase U32
CS550_RS03185	COG0101	tRNA pseudouridine synthase activity
CS550_RS03220	COG0544	peptidyl-prolyl cis-trans isomerase activity
CS550_RS03225	COG1185	polyribonucleotide nucleotidyltransferase activity
CS550_RS03230	COG1640	4-alpha-glucanotransferase
CS550_RS03255	COG1960	acyl-CoA dehydrogenase activity
CS550_RS03260	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CS550_RS03265	COG2086	electron transfer activity
CS550_RS03270	COG1214	PFAM Peptidase M22, glycoprotease
CS550_RS03290	COG0811	peptide transport
CS550_RS03300	COG0084	hydrolase, TatD family'
CS550_RS03330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CS550_RS03335	COG0563	adenylate kinase activity
CS550_RS03340	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CS550_RS03345	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CS550_RS03350	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CS550_RS03355	COG0670	Belongs to the BI1 family
CS550_RS03360	COG0495	leucyl-tRNA aminoacylation
CS550_RS03375	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CS550_RS03380	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CS550_RS03380	COG0517	IMP dehydrogenase activity
CS550_RS03380	COG0617	tRNA 3'-terminal CCA addition
CS550_RS03390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS550_RS03395	COG0363	glucosamine-6-phosphate deaminase activity
CS550_RS03400	COG0426	domain, Protein
CS550_RS03405	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CS550_RS03410	COG0673	inositol 2-dehydrogenase activity
CS550_RS03415	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CS550_RS03425	COG0632	four-way junction helicase activity
CS550_RS03440	COG5433	transposase activity
CS550_RS03510	COG0534	Mate efflux family protein
CS550_RS03515	COG2207	Transcriptional regulator
CS550_RS03515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CS550_RS03545	COG4974	Belongs to the 'phage' integrase family
CS550_RS03550	COG4974	Belongs to the 'phage' integrase family
CS550_RS03630	COG3843	relaxase mobilization nuclease domain protein
CS550_RS03665	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CS550_RS03680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CS550_RS03685	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CS550_RS03705	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CS550_RS03715	COG0006	proline dipeptidase activity
CS550_RS03720	COG1785	Belongs to the alkaline phosphatase family
CS550_RS03735	COG0551	DNA topoisomerase type I activity
CS550_RS03735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CS550_RS03915	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CS550_RS03920	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CS550_RS03925	COG4948	Mandelate Racemase Muconate Lactonizing
CS550_RS03930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS550_RS03995	COG1309	transcriptional regulator
CS550_RS04010	COG1151	hydroxylamine reductase activity
CS550_RS04015	COG2003	Belongs to the UPF0758 family
CS550_RS04035	COG3250	beta-galactosidase activity
CS550_RS04040	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CS550_RS04045	COG1752	Esterase of the alpha-beta hydrolase superfamily
CS550_RS04050	COG1294	oxidase, subunit
CS550_RS04065	COG3537	Alpha-1,2-mannosidase
CS550_RS04090	COG3681	Belongs to the UPF0597 family
CS550_RS04125	COG2246	polysaccharide biosynthetic process
CS550_RS04135	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CS550_RS04140	COG0463	Glycosyl transferase, family 2
CS550_RS04145	COG4591	ABC-type transport system involved in lipoprotein release permease component
CS550_RS04150	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CS550_RS04155	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CS550_RS04160	COG1435	thymidine kinase activity
CS550_RS04170	COG0802	atpase or kinase
CS550_RS04175	COG2204	response regulator
CS550_RS04200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CS550_RS04205	COG1032	radical SAM domain protein
CS550_RS04210	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CS550_RS04215	COG2252	PERMEase
CS550_RS04225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CS550_RS04245	COG1668	transmembrane transport
CS550_RS04250	COG4152	abc transporter atp-binding protein
CS550_RS04270	COG0509	glycine decarboxylation via glycine cleavage system
CS550_RS04275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CS550_RS04280	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CS550_RS04285	COG0756	dUTP diphosphatase activity
CS550_RS04305	COG0196	riboflavin kinase activity
CS550_RS04310	COG1959	2 iron, 2 sulfur cluster binding
CS550_RS04310	COG1295	ribonuclease BN
CS550_RS04320	COG0489	protein tyrosine kinase activity
CS550_RS04325	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CS550_RS04335	COG0442	prolyl-tRNA aminoacylation
CS550_RS04345	COG1183	phosphatidylcholine synthase activity
CS550_RS04350	COG0688	phosphatidylethanolamine metabolic process
CS550_RS04385	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CS550_RS04400	COG1702	phosphate starvation-inducible protein PhoH
CS550_RS04405	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CS550_RS04410	COG2226	methyltransferase
CS550_RS04415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CS550_RS04420	COG0729	surface antigen
CS550_RS04455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CS550_RS04460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CS550_RS04465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CS550_RS04470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CS550_RS04530	COG1725	Transcriptional regulator
CS550_RS04545	COG1131	(ABC) transporter
CS550_RS04555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CS550_RS04560	COG0427	acetyl-CoA hydrolase
CS550_RS04570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CS550_RS04570	COG0574	Belongs to the PEP-utilizing enzyme family
CS550_RS04595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CS550_RS04600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CS550_RS04615	COG1131	(ABC) transporter
CS550_RS04655	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CS550_RS04660	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CS550_RS04670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CS550_RS04685	COG2194	sulfuric ester hydrolase activity
CS550_RS04690	COG1438	arginine binding
CS550_RS04705	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CS550_RS04725	COG0860	N-Acetylmuramoyl-L-alanine amidase
CS550_RS04745	COG0789	Transcriptional regulator
CS550_RS04750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CS550_RS04765	COG0720	synthase
CS550_RS04770	COG0602	queuosine metabolic process
CS550_RS04790	COG1556	Lactate utilization protein
CS550_RS04795	COG1139	Iron-sulfur cluster binding protein
CS550_RS04800	COG0247	lactate metabolic process
CS550_RS04805	COG0560	Phosphoserine phosphatase
CS550_RS04845	COG2096	Adenosyltransferase
CS550_RS04850	COG1492	cobalamin metabolic process
CS550_RS04855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CS550_RS04860	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CS550_RS04865	COG1187	pseudouridine synthase activity
CS550_RS04885	COG1979	alcohol dehydrogenase
CS550_RS04905	COG1022	Amp-dependent synthetase and ligase
CS550_RS04930	COG0438	transferase activity, transferring glycosyl groups
CS550_RS04960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CS550_RS04965	COG0492	ferredoxin-NADP+ reductase activity
CS550_RS04980	COG0525	valine-tRNA ligase activity
CS550_RS05000	COG1570	exodeoxyribonuclease VII activity
CS550_RS05005	COG1522	sequence-specific DNA binding
CS550_RS05010	COG2233	PERMEase
CS550_RS05020	COG2096	Adenosyltransferase
CS550_RS05030	COG1187	pseudouridine synthase activity
CS550_RS05035	COG0017	Asparaginyl-tRNA synthetase
CS550_RS05045	COG0542	response to heat
CS550_RS05050	COG0534	Mate efflux family protein
CS550_RS05055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CS550_RS05060	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CS550_RS05065	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CS550_RS05070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CS550_RS05075	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CS550_RS05080	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CS550_RS05085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CS550_RS05095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CS550_RS05105	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CS550_RS05125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CS550_RS05135	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CS550_RS05175	COG1242	4 iron, 4 sulfur cluster binding
CS550_RS05185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS550_RS05195	COG0280	phosphate acetyltransferase
CS550_RS05200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CS550_RS05210	COG1024	Enoyl-CoA hydratase
CS550_RS05215	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CS550_RS05220	COG2086	electron transfer activity
CS550_RS05225	COG1960	acyl-CoA dehydrogenase activity
CS550_RS05235	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CS550_RS05240	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CS550_RS05245	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CS550_RS05260	COG0604	alcohol dehydrogenase
CS550_RS05265	COG3246	L-lysine catabolic process to acetate
CS550_RS05270	COG1607	acyl-coa hydrolase
CS550_RS05280	COG0167	dihydroorotate dehydrogenase activity
CS550_RS05295	COG5433	transposase activity
CS550_RS05305	COG0793	Belongs to the peptidase S41A family
CS550_RS05315	COG1132	(ABC) transporter
CS550_RS05345	COG1696	Membrane protein involved in D-alanine export
CS550_RS05370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CS550_RS05420	COG0443	Heat shock 70 kDa protein
CS550_RS05440	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CS550_RS05450	COG0328	RNA-DNA hybrid ribonuclease activity
CS550_RS05450	COG3341	Caulimovirus viroplasmin
CS550_RS05480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS550_RS05500	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CS550_RS05505	COG0488	(ABC) transporter
CS550_RS05510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CS550_RS05525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CS550_RS05540	COG2197	response regulator
CS550_RS05545	COG0564	pseudouridine synthase activity
CS550_RS05555	COG1309	transcriptional regulator
CS550_RS05565	COG0481	GTPase activity
CS550_RS05570	COG0305	Participates in initiation and elongation during chromosome replication
CS550_RS05585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CS550_RS05590	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CS550_RS05625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CS550_RS05635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CS550_RS05640	COG1530	ribonuclease E activity
CS550_RS05650	COG0602	queuosine metabolic process
CS550_RS05655	COG1328	CTP reductase activity
CS550_RS05660	COG5433	transposase activity
CS550_RS05710	COG1012	belongs to the aldehyde dehydrogenase family
CS550_RS05720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CS550_RS05725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CS550_RS05740	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CS550_RS05745	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CS550_RS05760	COG1193	negative regulation of DNA recombination
CS550_RS05770	COG3591	Belongs to the peptidase S1B family
CS550_RS05775	COG0363	glucosamine-6-phosphate deaminase activity
CS550_RS05785	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CS550_RS05790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CS550_RS05795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CS550_RS06015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CS550_RS06020	COG1309	transcriptional regulator
CS550_RS06070	COG0582	viral genome integration into host DNA
CS550_RS06080	COG1918	ferrous iron import across plasma membrane
CS550_RS06080	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CS550_RS06130	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CS550_RS06130	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CS550_RS06135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CS550_RS06140	COG0357	Ribosomal RNA small subunit methyltransferase G
CS550_RS06150	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CS550_RS06190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CS550_RS06195	COG1047	Peptidyl-prolyl cis-trans
CS550_RS06225	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CS550_RS06230	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CS550_RS06235	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CS550_RS06245	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CS550_RS06245	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CS550_RS06270	COG1970	mechanosensitive ion channel activity
CS550_RS06285	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CS550_RS06315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CS550_RS06320	COG1620	l-lactate permease
CS550_RS06330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CS550_RS06335	COG0321	lipoyl(octanoyl) transferase activity
CS550_RS06335	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CS550_RS06350	COG0438	transferase activity, transferring glycosyl groups
CS550_RS06355	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CS550_RS06360	COG1597	lipid kinase activity
CS550_RS06375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CS550_RS06380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CS550_RS06405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CS550_RS06420	COG0823	Involved in the tonB-independent uptake of proteins
CS550_RS06420	COG1506	peptidase
CS550_RS06425	COG0116	Belongs to the methyltransferase superfamily
CS550_RS06435	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CS550_RS06440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CS550_RS06445	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CS550_RS06455	COG0166	Belongs to the GPI family
CS550_RS06465	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CS550_RS06495	COG1194	a g-specific adenine glycosylase
CS550_RS06500	COG1116	anion transmembrane transporter activity
CS550_RS06500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CS550_RS06525	COG3421	Type III restriction
CS550_RS06525	COG3421	Type III restriction
CS550_RS06530	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CS550_RS06540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CS550_RS06585	COG0772	Belongs to the SEDS family
CS550_RS06590	COG0768	penicillin binding
CS550_RS06610	COG0138	bifunctional purine biosynthesis protein purh
CS550_RS06630	COG3033	Beta-eliminating lyase
CS550_RS06675	COG0569	domain protein
CS550_RS06675	COG2985	domain, Protein
CS550_RS06710	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CS550_RS06725	COG2027	D-alanyl-D-alanine carboxypeptidase
CS550_RS06735	COG2957	Belongs to the agmatine deiminase family
CS550_RS06745	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CS550_RS06755	COG2197	response regulator
CS550_RS06760	COG0784	Response regulator, receiver
CS550_RS06760	COG2205	protein histidine kinase activity
CS550_RS06760	COG5002	protein histidine kinase activity
CS550_RS06770	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CS550_RS06835	COG1968	undecaprenyl-diphosphatase activity
CS550_RS06840	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CS550_RS06845	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CS550_RS06850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CS550_RS06855	COG0826	peptidase U32
CS550_RS06865	COG3022	response to hydroperoxide
CS550_RS06870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CS550_RS06900	COG4771	TonB-dependent receptor
CS550_RS06905	COG1429	ligase activity, forming nitrogen-metal bonds
CS550_RS06925	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CS550_RS06945	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CS550_RS06960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CS550_RS06980	COG0730	response to heat
CS550_RS06985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CS550_RS06990	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CS550_RS07000	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CS550_RS07005	COG0714	Associated with various cellular activities
CS550_RS07045	COG0671	phosphoesterase, PA-phosphatase related
CS550_RS07050	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CS550_RS07055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CS550_RS07070	COG1480	7TM receptor with intracellular HD hydrolase
CS550_RS07075	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CS550_RS07085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CS550_RS07090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CS550_RS07095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CS550_RS07100	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CS550_RS07115	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CS550_RS07115	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CS550_RS07125	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CS550_RS07140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CS550_RS07165	COG0511	ligase activity, forming carbon-carbon bonds
CS550_RS07180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CS550_RS07185	COG0346	lactoylglutathione lyase activity
CS550_RS07195	COG1053	succinate dehydrogenase
CS550_RS07210	COG2217	Heavy metal translocating P-type atpase
CS550_RS07210	COG2608	mercury ion transmembrane transporter activity
CS550_RS07215	COG2217	Heavy metal translocating P-type atpase
CS550_RS07220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CS550_RS07225	COG0534	Mate efflux family protein
CS550_RS07230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS550_RS07235	COG1674	ftsk spoiiie
CS550_RS07250	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CS550_RS07320	COG0500	methyltransferase
CS550_RS07325	COG2830	Protein of unknown function (DUF452)
CS550_RS07350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS550_RS07375	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CS550_RS07400	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CS550_RS07405	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CS550_RS07405	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CS550_RS07435	COG1136	(ABC) transporter
CS550_RS07440	COG1136	(ABC) transporter
CS550_RS07440	COG0577	efflux transmembrane transporter activity
CS550_RS07445	COG1136	(ABC) transporter
CS550_RS07445	COG0577	efflux transmembrane transporter activity
CS550_RS07515	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CS550_RS07520	COG0126	phosphoglycerate kinase activity
CS550_RS07530	COG1131	(ABC) transporter
CS550_RS07540	COG0438	transferase activity, transferring glycosyl groups
CS550_RS07570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CS550_RS07575	COG0009	L-threonylcarbamoyladenylate synthase
CS550_RS07585	COG1136	(ABC) transporter
CS550_RS07595	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CS550_RS07620	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CS550_RS07625	COG0187	DNA topoisomerase II activity
CS550_RS07630	COG3956	TIGRFAM MazG family protein
CS550_RS07640	COG0564	pseudouridine synthase activity
CS550_RS07680	COG0259	pyridoxamine-phosphate oxidase activity
CS550_RS07700	COG1132	(ABC) transporter
CS550_RS07710	COG0557	exoribonuclease II activity
CS550_RS07725	COG0268	Binds directly to 16S ribosomal RNA
CS550_RS07735	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CS550_RS07740	COG1546	Belongs to the CinA family
CS550_RS07740	COG1058	Belongs to the CinA family
CS550_RS07755	COG0590	tRNA wobble adenosine to inosine editing
CS550_RS07760	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CS550_RS07770	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CS550_RS07775	COG4974	Belongs to the 'phage' integrase family
CS550_RS07795	COG1940	carbohydrate kinase activity
CS550_RS07805	COG0248	Ppx GppA phosphatase
CS550_RS07810	COG1027	Aspartate ammonia-lyase
CS550_RS07815	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CS550_RS07820	COG0572	uridine kinase
CS550_RS07845	COG1253	flavin adenine dinucleotide binding
CS550_RS07850	COG0629	single-stranded DNA binding
CS550_RS07855	COG0583	DNA-binding transcription factor activity
CS550_RS07860	COG0708	Exodeoxyribonuclease III
CS550_RS07865	COG0482	sulfurtransferase activity
CS550_RS07870	COG0018	arginyl-trna synthetase
CS550_RS07890	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CS550_RS07905	COG0719	Fe-S assembly protein
CS550_RS07910	COG0396	ATPase activity
CS550_RS07915	COG0719	Fe-S assembly protein
CS550_RS07925	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CS550_RS07925	COG3266	domain, Protein
CS550_RS07930	COG0195	Participates in both transcription termination and antitermination
CS550_RS07935	COG0779	Required for maturation of 30S ribosomal subunits
CS550_RS07975	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CS550_RS07985	COG1011	Hydrolase
CS550_RS07990	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CS550_RS08025	COG3876	Protein conserved in bacteria
CS550_RS08030	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CS550_RS08045	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CS550_RS08055	COG2095	MarC family integral membrane protein
CS550_RS08125	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CS550_RS08130	COG2116	formate transmembrane transporter activity
CS550_RS08140	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CS550_RS08160	COG0594	ribonuclease P activity
CS550_RS08165	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CS550_RS08170	COG0084	hydrolase, TatD family'
CS550_RS08175	COG3152	Membrane
CS550_RS08180	COG0612	Peptidase, M16
CS550_RS08185	COG1592	Rubrerythrin
CS550_RS08195	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CS550_RS08205	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CS550_RS08220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CS550_RS08230	COG1629	transport
CS550_RS08265	COG0446	pyridine nucleotide-disulphide oxidoreductase
CS550_RS08280	COG0737	Belongs to the 5'-nucleotidase family
CS550_RS08285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CS550_RS08285	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CS550_RS08295	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CS550_RS08300	COG0193	aminoacyl-tRNA hydrolase activity
CS550_RS08305	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CS550_RS08330	COG3590	peptidase
CS550_RS08335	COG1040	competence protein
CS550_RS08340	COG2137	regulation of response to DNA damage stimulus
CS550_RS08345	COG2890	protein-(glutamine-N5) methyltransferase activity
CS550_RS08350	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CS550_RS08350	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CS550_RS08355	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CS550_RS08365	COG0552	protein localization to endoplasmic reticulum
CS550_RS08370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CS550_RS08400	COG2957	Belongs to the agmatine deiminase family
CS550_RS08410	COG1192	Involved in chromosome partitioning
CS550_RS08415	COG1475	DNA binding
CS550_RS08425	COG3942	CHAP domain
CS550_RS08425	COG1388	LysM domain
CS550_RS08430	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CS550_RS08435	COG2195	Cleaves the N-terminal amino acid of tripeptides
CS550_RS08445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CS550_RS08450	COG2239	Acts as a magnesium transporter
CS550_RS08470	COG0588	phosphoglycerate mutase activity
CS550_RS08475	COG0438	transferase activity, transferring glycosyl groups
CS550_RS08485	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CS550_RS08500	COG1739	Uncharacterized protein family UPF0029
CS550_RS08510	COG0776	regulation of translation
CS550_RS08525	COG1216	Glycosyl transferase, family 2
CS550_RS08555	COG0438	transferase activity, transferring glycosyl groups
CS550_RS08585	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CS550_RS08590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CS550_RS08600	COG0551	DNA topoisomerase type I activity
CS550_RS08600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CS550_RS08655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS550_RS08660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CS550_RS08665	COG3104	oligopeptide transport
CS550_RS08680	COG0180	Tryptophanyl-tRNA synthetase
CS550_RS08690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CS550_RS08740	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CS550_RS08745	COG0513	Belongs to the DEAD box helicase family
CS550_RS08790	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CS550_RS08795	COG2022	thiamine diphosphate biosynthetic process
CS550_RS08800	COG0352	thiamine-phosphate diphosphorylase activity
CS550_RS08805	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CS550_RS08840	COG0228	four-way junction DNA binding
CS550_RS08855	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CS550_RS08860	COG0252	asparaginase activity
CS550_RS08885	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CS550_RS08945	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CS550_RS08950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CS550_RS08955	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CS550_RS08960	COG1160	GTP binding
CS550_RS08970	COG0726	polysaccharide deacetylase
CS550_RS08980	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CS550_RS08985	COG2233	PERMEase
CS550_RS09030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CS550_RS09040	COG2166	iron-sulfur cluster assembly
CS550_RS09045	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CS550_RS09060	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CS550_RS09065	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CS550_RS09075	COG0423	glycine-tRNA ligase activity
CS550_RS09110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CS550_RS09145	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CS550_RS09150	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CS550_RS09155	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CS550_RS09165	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CS550_RS09185	COG1575	Belongs to the MenA family. Type 1 subfamily
CS550_RS09190	COG0019	diaminopimelate decarboxylase activity
CS550_RS09195	COG0527	aspartate kinase activity
CS550_RS09200	COG2884	Cell division ATP-binding protein ftsE
CS550_RS09210	COG0739	heme binding
CS550_RS09215	COG0012	GTP binding
CS550_RS09220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CS550_RS09225	COG4589	Belongs to the CDS family
CS550_RS09230	COG0326	Molecular chaperone. Has ATPase activity
CS550_RS09240	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CS550_RS09245	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CS550_RS09255	COG0335	large ribosomal subunit rRNA binding
CS550_RS09265	COG3118	belongs to the thioredoxin family
CS550_RS09290	COG0295	cytidine deaminase activity
CS550_RS09305	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CS550_RS09320	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS550_RS09325	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CS550_RS09330	COG0659	secondary active sulfate transmembrane transporter activity
CS550_RS09350	COG2205	protein histidine kinase activity
CS550_RS09365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CS550_RS09370	COG1472	Belongs to the glycosyl hydrolase 3 family
CS550_RS09375	COG0542	response to heat
CS550_RS09400	COG1408	metallophosphoesterase
CS550_RS09405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CS550_RS09420	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CS550_RS09450	COG0463	Glycosyl transferase, family 2
CS550_RS09460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CS550_RS09480	COG0569	domain protein
CS550_RS09485	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CS550_RS09510	COG5433	transposase activity
CS550_RS09550	COG0488	(ABC) transporter
CS550_RS09555	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CS550_RS09570	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CS550_RS09575	COG0242	peptide deformylase activity
CS550_RS09585	COG0488	(ABC) transporter
CS550_RS09590	COG2957	Belongs to the agmatine deiminase family
CS550_RS09600	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CS550_RS09605	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CS550_RS09610	COG0124	histidyl-tRNA synthetase
CS550_RS09625	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CS550_RS09635	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CS550_RS09645	COG0300	oxidoreductase activity
CS550_RS09660	COG1074	ATP-dependent DNA helicase activity
CS550_RS09715	COG0217	transcriptional regulatory protein
CS550_RS09720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CS550_RS09750	COG0783	Belongs to the Dps family
CS550_RS09760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CS550_RS09760	COG0517	IMP dehydrogenase activity
CS550_RS09775	COG1760	l-serine dehydratase
CS550_RS09815	COG1705	Flagellar rod assembly protein muramidase FlgJ
CS550_RS09815	COG1388	LysM domain
CS550_RS09820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CS550_RS09825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CS550_RS09830	COG0284	orotidine-5'-phosphate decarboxylase activity
CS550_RS09835	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CS550_RS09840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CS550_RS09840	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CS550_RS09845	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CS550_RS09850	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CS550_RS09850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CS550_RS09875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CS550_RS09880	COG1649	PFAM Uncharacterised BCR, COG1649
CS550_RS09895	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CS550_RS09900	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CS550_RS09915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CS550_RS09915	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CS550_RS09920	COG3852	Histidine kinase
CS550_RS09940	COG0167	dihydroorotate dehydrogenase activity
CS550_RS09955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS550_RS09975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CS550_RS09980	COG0037	tRNA processing
CS550_RS09990	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CS550_RS10000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS550_RS10010	COG0336	Belongs to the RNA methyltransferase TrmD family
CS550_RS10015	COG0543	2 iron, 2 sulfur cluster binding
CS550_RS10020	COG0493	'glutamate synthase
CS550_RS10025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CS550_RS10050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CS550_RS10060	COG0406	alpha-ribazole phosphatase activity
CS550_RS10065	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CS550_RS10075	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CS550_RS10085	COG3119	arylsulfatase activity
CS550_RS10105	COG1203	CRISPR-associated helicase, Cas3
CS550_RS10125	COG1518	maintenance of DNA repeat elements
CS550_RS10130	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CS550_RS10155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CS550_RS10160	COG1381	Involved in DNA repair and RecF pathway recombination
CS550_RS10165	COG4771	TonB-dependent receptor
CS550_RS10175	COG2855	membrane
CS550_RS10180	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CS550_RS10185	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CS550_RS10205	COG0142	geranyltranstransferase activity
CS550_RS10220	COG1490	D-aminoacyl-tRNA deacylase activity
CS550_RS10225	COG0322	excinuclease ABC activity
CS550_RS10230	COG0445	tRNA wobble uridine modification
CS550_RS10270	COG1337	RAMP superfamily
CS550_RS10320	COG0668	transmembrane transport
CS550_RS10330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CS550_RS10355	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CS550_RS10360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CS550_RS10375	COG0427	acetyl-CoA hydrolase
CS550_RS10395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CS550_RS10400	COG0628	permease
CS550_RS10425	COG1108	ABC-type Mn2 Zn2 transport systems permease components