locus-tag	class	description
PMN2A_RS00015	COG0592	DNA-directed DNA polymerase activity
PMN2A_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PMN2A_RS00055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PMN2A_RS00060	COG0552	protein localization to endoplasmic reticulum
PMN2A_RS00065	COG2208	phosphoserine phosphatase activity
PMN2A_RS00075	COG0724	RNA recognition motif
PMN2A_RS00080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PMN2A_RS00095	COG0484	heat shock protein binding
PMN2A_RS00125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PMN2A_RS00130	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PMN2A_RS00135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PMN2A_RS00145	COG0511	ligase activity, forming carbon-carbon bonds
PMN2A_RS00150	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PMN2A_RS00215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PMN2A_RS00240	COG0768	penicillin binding
PMN2A_RS00250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PMN2A_RS00250	COG0426	domain, Protein
PMN2A_RS00255	COG0426	domain, Protein
PMN2A_RS00255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PMN2A_RS00265	COG1166	arginine decarboxylase activity
PMN2A_RS00275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMN2A_RS00275	COG2022	thiamine diphosphate biosynthetic process
PMN2A_RS00405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PMN2A_RS00440	COG1132	(ABC) transporter
PMN2A_RS00450	COG0438	transferase activity, transferring glycosyl groups
PMN2A_RS00465	COG0116	Belongs to the methyltransferase superfamily
PMN2A_RS00485	COG1196	nuclear chromosome segregation
PMN2A_RS00495	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PMN2A_RS00505	COG0439	Biotin carboxylase
PMN2A_RS00520	COG0515	serine threonine protein kinase
PMN2A_RS00530	COG4178	(ABC) transporter
PMN2A_RS00540	COG0537	adenosine 5'-monophosphoramidase activity
PMN2A_RS00550	COG0823	Involved in the tonB-independent uptake of proteins
PMN2A_RS00550	COG4946	Tricorn protease homolog
PMN2A_RS00550	COG1506	peptidase
PMN2A_RS00555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PMN2A_RS00560	COG0719	Fe-S assembly protein
PMN2A_RS00565	COG0396	ATPase activity
PMN2A_RS00570	COG0719	Fe-S assembly protein
PMN2A_RS00590	COG0033	Phosphoglucomutase
PMN2A_RS00595	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PMN2A_RS00605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PMN2A_RS00610	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PMN2A_RS00615	COG0175	sulfate reduction
PMN2A_RS00620	COG1252	NADH dehydrogenase
PMN2A_RS00625	COG3273	potassium ion transport
PMN2A_RS00625	COG0471	metal ion transport
PMN2A_RS00630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PMN2A_RS00635	COG0569	domain protein
PMN2A_RS00660	COG0488	(ABC) transporter
PMN2A_RS00665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PMN2A_RS00680	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PMN2A_RS00685	COG1570	exodeoxyribonuclease VII activity
PMN2A_RS00690	COG1722	exodeoxyribonuclease VII activity
PMN2A_RS00705	COG0483	inositol monophosphate 1-phosphatase activity
PMN2A_RS00710	COG1538	Outer membrane efflux protein
PMN2A_RS00730	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PMN2A_RS00735	COG4243	Vitamin k epoxide reductase
PMN2A_RS00760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PMN2A_RS00760	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PMN2A_RS00800	COG1472	Belongs to the glycosyl hydrolase 3 family
PMN2A_RS00805	COG1587	Uroporphyrinogen-III synthase
PMN2A_RS00815	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
PMN2A_RS00820	COG0316	Belongs to the HesB IscA family
PMN2A_RS00830	COG1090	epimerase
PMN2A_RS00840	COG0484	heat shock protein binding
PMN2A_RS00845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PMN2A_RS00860	COG1122	ATPase activity
PMN2A_RS00870	COG0745	RESPONSE REGULATOR receiver
PMN2A_RS00875	COG0470	DNA polymerase III
PMN2A_RS00885	COG2217	Heavy metal translocating P-type atpase
PMN2A_RS00895	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PMN2A_RS00905	COG0416	fatty acid biosynthetic process
PMN2A_RS00915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PMN2A_RS00945	COG1562	ergosterol biosynthetic process
PMN2A_RS00950	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
PMN2A_RS00950	COG0493	'glutamate synthase
PMN2A_RS00965	COG0583	DNA-binding transcription factor activity
PMN2A_RS00975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PMN2A_RS00990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PMN2A_RS01015	COG0713	ATP synthesis coupled electron transport
PMN2A_RS01035	COG0372	Belongs to the citrate synthase family
PMN2A_RS01045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PMN2A_RS01045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PMN2A_RS01055	COG0023	Translation Initiation Factor
PMN2A_RS01060	COG0529	Catalyzes the synthesis of activated sulfate
PMN2A_RS01065	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PMN2A_RS01075	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PMN2A_RS01080	COG0745	RESPONSE REGULATOR receiver
PMN2A_RS01085	COG1104	cysteine desulfurase activity
PMN2A_RS01105	COG0318	PFAM AMP-dependent synthetase and ligase
PMN2A_RS01115	COG1575	Belongs to the MenA family. Type 1 subfamily
PMN2A_RS01120	COG1169	isochorismate synthase
PMN2A_RS01125	COG0189	ligase activity
PMN2A_RS01135	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PMN2A_RS01150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PMN2A_RS01170	COG0157	Belongs to the NadC ModD family
PMN2A_RS01185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PMN2A_RS01195	COG0564	pseudouridine synthase activity
PMN2A_RS01200	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PMN2A_RS01220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PMN2A_RS01225	COG0167	dihydroorotate dehydrogenase activity
PMN2A_RS01245	COG0081	regulation of translation
PMN2A_RS01250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PMN2A_RS01255	COG0250	Participates in transcription elongation, termination and antitermination
PMN2A_RS01260	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PMN2A_RS01265	COG0542	response to heat
PMN2A_RS01275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PMN2A_RS01285	COG0492	ferredoxin-NADP+ reductase activity
PMN2A_RS01300	COG0659	secondary active sulfate transmembrane transporter activity
PMN2A_RS01305	COG0484	heat shock protein binding
PMN2A_RS01310	COG0113	porphobilinogen synthase activity
PMN2A_RS01320	COG1193	negative regulation of DNA recombination
PMN2A_RS01345	COG0435	Glutathione S-transferase
PMN2A_RS01370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PMN2A_RS01375	COG2046	Belongs to the sulfate adenylyltransferase family
PMN2A_RS01385	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PMN2A_RS01400	COG2094	Belongs to the DNA glycosylase MPG family
PMN2A_RS01440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PMN2A_RS01445	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
PMN2A_RS01450	COG0717	Belongs to the dCTP deaminase family
PMN2A_RS01460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PMN2A_RS01465	COG4372	Transposase
PMN2A_RS01485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PMN2A_RS01500	COG0066	3-isopropylmalate dehydratase activity
PMN2A_RS01535	COG0728	peptidoglycan biosynthetic process
PMN2A_RS01545	COG0004	ammonium transporteR
PMN2A_RS01550	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PMN2A_RS01575	COG2205	protein histidine kinase activity
PMN2A_RS01580	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PMN2A_RS01585	COG0343	queuine tRNA-ribosyltransferase activity
PMN2A_RS01595	COG0673	inositol 2-dehydrogenase activity
PMN2A_RS01600	COG1253	flavin adenine dinucleotide binding
PMN2A_RS01610	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PMN2A_RS01615	COG0354	folic acid binding
PMN2A_RS01625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PMN2A_RS01630	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PMN2A_RS01635	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
PMN2A_RS01640	COG0131	Imidazoleglycerol-phosphate dehydratase
PMN2A_RS01645	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PMN2A_RS01660	COG0415	Belongs to the DNA photolyase family
PMN2A_RS01665	COG0494	nUDIX hydrolase
PMN2A_RS01670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PMN2A_RS01675	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
PMN2A_RS01675	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
PMN2A_RS01685	COG3842	ATPase activity
PMN2A_RS01690	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PMN2A_RS01705	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PMN2A_RS01710	COG1773	rubredoxin
PMN2A_RS01730	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PMN2A_RS01735	COG0709	Synthesizes selenophosphate from selenide and ATP
PMN2A_RS01740	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PMN2A_RS01740	COG0617	tRNA 3'-terminal CCA addition
PMN2A_RS01740	COG0517	IMP dehydrogenase activity
PMN2A_RS01800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PMN2A_RS01855	COG0539	negative regulation of cytoplasmic translation
PMN2A_RS01860	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PMN2A_RS01875	COG0824	Thioesterase
PMN2A_RS01880	COG2890	protein-(glutamine-N5) methyltransferase activity
PMN2A_RS01900	COG2894	cell division
PMN2A_RS01905	COG0850	regulation of cytokinetic process
PMN2A_RS01910	COG1078	dGTPase activity
PMN2A_RS01915	COG0793	Belongs to the peptidase S41A family
PMN2A_RS01920	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PMN2A_RS01925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PMN2A_RS01975	COG1705	Flagellar rod assembly protein muramidase FlgJ
PMN2A_RS01975	COG1388	LysM domain
PMN2A_RS01980	COG1012	belongs to the aldehyde dehydrogenase family
PMN2A_RS02075	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PMN2A_RS02075	COG1648	precorrin-2 dehydrogenase activity
PMN2A_RS02080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PMN2A_RS02095	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PMN2A_RS02115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PMN2A_RS02120	COG0438	transferase activity, transferring glycosyl groups
PMN2A_RS02130	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PMN2A_RS02135	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PMN2A_RS02145	COG1022	Amp-dependent synthetase and ligase
PMN2A_RS02155	COG0508	dehydrogenase complex catalyzes the overall conversion of
PMN2A_RS02165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PMN2A_RS02170	COG0626	cystathionine gamma-synthase activity
PMN2A_RS02175	COG0626	cystathionine gamma-synthase activity
PMN2A_RS02220	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PMN2A_RS02240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PMN2A_RS02245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PMN2A_RS02255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PMN2A_RS02255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PMN2A_RS02260	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PMN2A_RS02275	COG2226	methyltransferase
PMN2A_RS02285	COG1842	Phage shock protein A
PMN2A_RS02290	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PMN2A_RS02290	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PMN2A_RS02295	COG1136	(ABC) transporter
PMN2A_RS02305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PMN2A_RS02320	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PMN2A_RS02340	COG1845	cytochrome c oxidase, subunit III
PMN2A_RS02345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PMN2A_RS02355	COG1612	heme a metabolic process
PMN2A_RS02385	COG1028	Short-chain dehydrogenase reductase Sdr
PMN2A_RS02395	COG1619	proteins homologs of microcin C7 resistance protein MccF
PMN2A_RS02400	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PMN2A_RS02430	COG0723	plastoquinol--plastocyanin reductase activity
PMN2A_RS02440	COG0805	protein transport
PMN2A_RS02510	COG0024	Methionine aminopeptidase
PMN2A_RS02515	COG3000	fatty acid hydroxylase
PMN2A_RS02515	COG0300	oxidoreductase activity
PMN2A_RS02520	COG0857	belongs to the CobB CobQ family
PMN2A_RS02565	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PMN2A_RS02575	COG4176	ABC-type proline glycine betaine transport system permease component
PMN2A_RS02580	COG0523	cobalamin synthesis protein
PMN2A_RS02590	COG0432	Pfam Uncharacterised protein family UPF0047
PMN2A_RS02600	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PMN2A_RS02610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PMN2A_RS02615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PMN2A_RS02640	COG0629	single-stranded DNA binding
PMN2A_RS02655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PMN2A_RS02660	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PMN2A_RS02685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PMN2A_RS02715	COG0768	penicillin binding
PMN2A_RS02735	COG0528	UMP kinase activity
PMN2A_RS02745	COG0582	viral genome integration into host DNA
PMN2A_RS02755	COG0028	Belongs to the TPP enzyme family
PMN2A_RS02770	COG0539	negative regulation of cytoplasmic translation
PMN2A_RS02780	COG3396	Phenylacetate-CoA oxygenase
PMN2A_RS02785	COG5322	oxidoreductase activity
PMN2A_RS02795	COG1028	Short-chain dehydrogenase reductase Sdr
PMN2A_RS02800	COG0135	phosphoribosylanthranilate isomerase activity
PMN2A_RS02805	COG0517	IMP dehydrogenase activity
PMN2A_RS02805	COG1994	Peptidase M50
PMN2A_RS02810	COG0095	Lipoate-protein ligase
PMN2A_RS02825	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
PMN2A_RS02845	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
PMN2A_RS02850	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PMN2A_RS02855	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
PMN2A_RS02860	COG1850	ribulose-bisphosphate carboxylase activity
PMN2A_RS02865	COG4451	ribulose bisphosphate carboxylase, small
PMN2A_RS02890	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
PMN2A_RS02905	COG0251	oxidation-reduction process
PMN2A_RS02915	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PMN2A_RS02920	COG1132	(ABC) transporter
PMN2A_RS02925	COG0456	acetyltransferase
PMN2A_RS02940	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PMN2A_RS02950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PMN2A_RS02960	COG0418	dihydroorotase activity
PMN2A_RS02990	COG2010	Cytochrome c
PMN2A_RS03005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PMN2A_RS03010	COG0140	phosphoribosyl-ATP diphosphatase activity
PMN2A_RS03010	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PMN2A_RS03020	COG0542	response to heat
PMN2A_RS03025	COG3794	PFAM blue (type 1) copper domain protein
PMN2A_RS03085	COG0339	signal peptide processing
PMN2A_RS03090	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PMN2A_RS03100	COG0837	glucose binding
PMN2A_RS03110	COG0180	Tryptophanyl-tRNA synthetase
PMN2A_RS03130	COG1121	(ABC) transporter
PMN2A_RS03135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PMN2A_RS03150	COG0681	Belongs to the peptidase S26 family
PMN2A_RS03160	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PMN2A_RS03170	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PMN2A_RS03190	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PMN2A_RS03205	COG0860	N-Acetylmuramoyl-L-alanine amidase
PMN2A_RS03215	COG0142	geranyltranstransferase activity
PMN2A_RS03220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PMN2A_RS03225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PMN2A_RS03235	COG2176	DNA-directed DNA polymerase activity
PMN2A_RS03250	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PMN2A_RS03305	COG0300	oxidoreductase activity
PMN2A_RS03310	COG0644	oxidoreductase
PMN2A_RS03330	COG0735	belongs to the Fur family
PMN2A_RS03365	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
PMN2A_RS03415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PMN2A_RS03420	COG2226	methyltransferase
PMN2A_RS03425	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PMN2A_RS03455	COG1836	PFAM Integral membrane protein DUF92
PMN2A_RS03470	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PMN2A_RS03475	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PMN2A_RS03480	COG0436	Aminotransferase
PMN2A_RS03490	COG1573	uracil-dna glycosylase
PMN2A_RS03495	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PMN2A_RS03500	COG0793	Belongs to the peptidase S41A family
PMN2A_RS03510	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PMN2A_RS03535	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PMN2A_RS03605	COG2081	HI0933 family
PMN2A_RS03635	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PMN2A_RS03640	COG0515	serine threonine protein kinase
PMN2A_RS03655	COG2226	methyltransferase
PMN2A_RS03660	COG0174	glutamine synthetase
PMN2A_RS03665	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PMN2A_RS03680	COG1160	GTP binding
PMN2A_RS03685	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PMN2A_RS03705	COG0612	Peptidase, M16
PMN2A_RS03730	COG1216	Glycosyl transferase, family 2
PMN2A_RS03735	COG0052	Belongs to the universal ribosomal protein uS2 family
PMN2A_RS03750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PMN2A_RS03755	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PMN2A_RS03760	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PMN2A_RS03765	COG0751	glycine-tRNA ligase activity
PMN2A_RS03770	COG0644	oxidoreductase
PMN2A_RS03780	COG1217	gtp-binding protein TYPA
PMN2A_RS03795	COG1137	ATPase activity
PMN2A_RS03810	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PMN2A_RS03815	COG1494	fructose-1,6-bisphosphatase
PMN2A_RS03825	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PMN2A_RS03830	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PMN2A_RS03835	COG0363	glucosamine-6-phosphate deaminase activity
PMN2A_RS03860	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PMN2A_RS03875	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PMN2A_RS03885	COG3588	fructose-bisphosphate aldolase
PMN2A_RS03890	COG0673	inositol 2-dehydrogenase activity
PMN2A_RS03910	COG3954	Phosphoribulokinase
PMN2A_RS03955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PMN2A_RS03960	COG2197	response regulator
PMN2A_RS03975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PMN2A_RS03995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PMN2A_RS04000	COG3842	ATPase activity
PMN2A_RS04015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PMN2A_RS04030	COG1122	ATPase activity
PMN2A_RS04040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PMN2A_RS04060	COG0799	negative regulation of ribosome biogenesis
PMN2A_RS04070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PMN2A_RS04075	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
PMN2A_RS04095	COG2084	Dehydrogenase
PMN2A_RS04105	COG4555	ABC transporter
PMN2A_RS04160	COG0463	Glycosyl transferase, family 2
PMN2A_RS04165	COG0366	Alpha amylase catalytic
PMN2A_RS04170	COG3769	mannosylglycerate metabolic process
PMN2A_RS04215	COG1132	(ABC) transporter
PMN2A_RS04230	COG0505	Belongs to the CarA family
PMN2A_RS04240	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PMN2A_RS04245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PMN2A_RS04260	COG0587	DNA-directed DNA polymerase activity
PMN2A_RS04290	COG0358	DNA primase activity
PMN2A_RS04340	COG0508	dehydrogenase complex catalyzes the overall conversion of
PMN2A_RS04340	COG0022	dehydrogenase e1 component
PMN2A_RS04345	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PMN2A_RS04350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PMN2A_RS04395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PMN2A_RS04400	COG0577	efflux transmembrane transporter activity
PMN2A_RS04400	COG1136	(ABC) transporter
PMN2A_RS04405	COG0469	pyruvate kinase activity
PMN2A_RS04415	COG0762	integral membrane protein
PMN2A_RS04425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PMN2A_RS04450	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PMN2A_RS04455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PMN2A_RS04460	COG0326	Molecular chaperone. Has ATPase activity
PMN2A_RS04470	COG0483	inositol monophosphate 1-phosphatase activity
PMN2A_RS04485	COG0581	inorganic phosphate transmembrane transporter activity
PMN2A_RS04490	COG0573	inorganic phosphate transmembrane transporter activity
PMN2A_RS04495	COG0443	Heat shock 70 kDa protein
PMN2A_RS04500	COG0484	heat shock protein binding
PMN2A_RS04515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PMN2A_RS04520	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PMN2A_RS04520	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PMN2A_RS04550	COG1104	cysteine desulfurase activity
PMN2A_RS04570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PMN2A_RS04570	COG0426	domain, Protein
PMN2A_RS04580	COG1981	membrane
PMN2A_RS04595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PMN2A_RS04600	COG0646	methionine synthase
PMN2A_RS04600	COG1410	methionine synthase
PMN2A_RS04640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PMN2A_RS04645	COG0557	exoribonuclease II activity
PMN2A_RS04650	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PMN2A_RS04670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PMN2A_RS04725	COG0450	alkyl hydroperoxide reductase
PMN2A_RS04730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PMN2A_RS04735	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PMN2A_RS04750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PMN2A_RS04750	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PMN2A_RS04755	COG2119	membrane
PMN2A_RS04765	COG0557	exoribonuclease II activity
PMN2A_RS04770	COG0163	prenyltransferase activity
PMN2A_RS04785	COG0312	modulator of DNA gyrase
PMN2A_RS04790	COG0312	modulator of DNA gyrase
PMN2A_RS04800	COG0861	Integral membrane protein TerC family
PMN2A_RS04810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PMN2A_RS04850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PMN2A_RS04865	COG1429	ligase activity, forming nitrogen-metal bonds
PMN2A_RS04870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PMN2A_RS04885	COG1132	(ABC) transporter
PMN2A_RS04955	COG3340	Belongs to the peptidase S51 family
PMN2A_RS05065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PMN2A_RS05125	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PMN2A_RS05135	COG0011	TIGRFAM Protein of
PMN2A_RS05190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PMN2A_RS05195	COG0745	RESPONSE REGULATOR receiver
PMN2A_RS05200	COG5002	protein histidine kinase activity
PMN2A_RS05235	COG2059	Chromate
PMN2A_RS05245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PMN2A_RS05250	COG0640	Transcriptional regulator
PMN2A_RS05255	COG0798	PFAM Bile acid sodium symporter
PMN2A_RS05390	COG2135	peptidase activity
PMN2A_RS05475	COG1233	COG1233 Phytoene dehydrogenase and related
PMN2A_RS05585	COG0519	Catalyzes the synthesis of GMP from XMP
PMN2A_RS05585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PMN2A_RS05870	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PMN2A_RS06055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PMN2A_RS06100	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PMN2A_RS06120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PMN2A_RS06135	COG1187	pseudouridine synthase activity
PMN2A_RS06195	COG0765	amino acid transport
PMN2A_RS06200	COG4597	amino acid ABC transporter
PMN2A_RS06205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMN2A_RS06310	COG0659	secondary active sulfate transmembrane transporter activity
PMN2A_RS06345	COG1233	COG1233 Phytoene dehydrogenase and related
PMN2A_RS06350	COG0745	RESPONSE REGULATOR receiver
PMN2A_RS06360	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PMN2A_RS06365	COG0271	Belongs to the BolA IbaG family
PMN2A_RS06380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PMN2A_RS06390	COG1074	ATP-dependent DNA helicase activity
PMN2A_RS06395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PMN2A_RS06400	COG0513	Belongs to the DEAD box helicase family
PMN2A_RS06410	COG1132	(ABC) transporter
PMN2A_RS06425	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PMN2A_RS06445	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PMN2A_RS06450	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PMN2A_RS06455	COG0019	diaminopimelate decarboxylase activity
PMN2A_RS06465	COG0542	response to heat
PMN2A_RS06470	COG0371	Dehydrogenase
PMN2A_RS06485	COG0575	Belongs to the CDS family
PMN2A_RS06490	COG1982	Orn Lys Arg decarboxylase major
PMN2A_RS06495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PMN2A_RS06510	COG1640	4-alpha-glucanotransferase
PMN2A_RS06515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PMN2A_RS06520	COG0308	aminopeptidase N
PMN2A_RS06535	COG2205	protein histidine kinase activity
PMN2A_RS06545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PMN2A_RS06550	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PMN2A_RS06560	COG1797	cobyrinic acid a,c-diamide synthase activity
PMN2A_RS06585	COG1480	7TM receptor with intracellular HD hydrolase
PMN2A_RS06605	COG1543	Belongs to the glycosyl hydrolase 57 family
PMN2A_RS06610	COG0644	oxidoreductase
PMN2A_RS06615	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PMN2A_RS06620	COG0516	GMP reductase activity
PMN2A_RS06625	COG3118	belongs to the thioredoxin family
PMN2A_RS06640	COG2010	Cytochrome c
PMN2A_RS06645	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
PMN2A_RS06655	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
PMN2A_RS06665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PMN2A_RS06670	COG2166	iron-sulfur cluster assembly
PMN2A_RS06675	COG0460	homoserine dehydrogenase
PMN2A_RS06690	COG0601	transmembrane transport
PMN2A_RS06795	COG3046	protein related to deoxyribodipyrimidine photolyase
PMN2A_RS06800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PMN2A_RS06810	COG1028	Short-chain dehydrogenase reductase Sdr
PMN2A_RS06830	COG2308	Evidence 4 Homologs of previously reported genes of
PMN2A_RS06900	COG0012	GTP binding
PMN2A_RS06905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMN2A_RS06910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PMN2A_RS06910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PMN2A_RS06920	COG0733	neurotransmitter:sodium symporter activity
PMN2A_RS06960	COG0492	ferredoxin-NADP+ reductase activity
PMN2A_RS06965	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PMN2A_RS06985	COG2267	carboxylic ester hydrolase activity
PMN2A_RS06990	COG0440	acetolactate synthase activity
PMN2A_RS06995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PMN2A_RS07045	COG1840	ABC-type Fe3 transport system, periplasmic component
PMN2A_RS07130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PMN2A_RS07135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PMN2A_RS07165	COG0716	FMN binding
PMN2A_RS07175	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PMN2A_RS07185	COG0697	spore germination
PMN2A_RS07190	COG0616	signal peptide processing
PMN2A_RS07215	COG0706	membrane insertase activity
PMN2A_RS07230	COG0750	zinc metalloprotease
PMN2A_RS07245	COG1218	3'(2'),5'-bisphosphate nucleotidase
PMN2A_RS07250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PMN2A_RS07300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PMN2A_RS07340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PMN2A_RS07345	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PMN2A_RS07350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PMN2A_RS07355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PMN2A_RS07355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PMN2A_RS07395	COG0196	riboflavin kinase activity
PMN2A_RS07400	COG0352	thiamine-phosphate diphosphorylase activity
PMN2A_RS07415	COG1691	(AIR) carboxylase
PMN2A_RS07425	COG0336	Belongs to the RNA methyltransferase TrmD family
PMN2A_RS07430	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PMN2A_RS07440	COG0670	Belongs to the BI1 family
PMN2A_RS07445	COG1702	phosphate starvation-inducible protein PhoH
PMN2A_RS07455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PMN2A_RS07465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PMN2A_RS07470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PMN2A_RS07475	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PMN2A_RS07475	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PMN2A_RS07485	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PMN2A_RS07510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PMN2A_RS07515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PMN2A_RS07525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PMN2A_RS07530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PMN2A_RS07535	COG0285	dihydrofolate synthase activity
PMN2A_RS07575	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PMN2A_RS07585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PMN2A_RS07590	COG4956	integral membrane protein (PIN domain superfamily)
PMN2A_RS07595	COG0740	serine-type endopeptidase activity
PMN2A_RS07615	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PMN2A_RS07620	COG0438	transferase activity, transferring glycosyl groups
PMN2A_RS07660	COG0776	regulation of translation
PMN2A_RS07675	COG2211	Major facilitator Superfamily
PMN2A_RS07680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PMN2A_RS07720	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PMN2A_RS07725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PMN2A_RS07735	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PMN2A_RS07740	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PMN2A_RS07745	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PMN2A_RS07760	COG0151	Belongs to the GarS family
PMN2A_RS07765	COG5002	protein histidine kinase activity
PMN2A_RS07770	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
PMN2A_RS07785	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PMN2A_RS07800	COG2385	sporulation resulting in formation of a cellular spore
PMN2A_RS07830	COG2264	protein methyltransferase activity
PMN2A_RS07835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PMN2A_RS07845	COG2302	S4 RNA-binding domain
PMN2A_RS07975	COG0488	(ABC) transporter
PMN2A_RS08060	COG0443	Heat shock 70 kDa protein
PMN2A_RS08080	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PMN2A_RS08100	COG0006	proline dipeptidase activity
PMN2A_RS08105	COG1253	flavin adenine dinucleotide binding
PMN2A_RS08115	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PMN2A_RS08120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PMN2A_RS08120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PMN2A_RS08125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PMN2A_RS08150	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PMN2A_RS08160	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PMN2A_RS08165	COG0356	it plays a direct role in the translocation of protons across the membrane
PMN2A_RS08175	COG0772	Belongs to the SEDS family
PMN2A_RS08205	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
PMN2A_RS08215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PMN2A_RS08220	COG0114	fumarate hydratase activity
PMN2A_RS08225	COG4581	dead DEAH box helicase
PMN2A_RS08230	COG0156	8-amino-7-oxononanoate synthase activity
PMN2A_RS08245	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PMN2A_RS08250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PMN2A_RS08320	COG0084	hydrolase, TatD family'
PMN2A_RS08325	COG0268	Binds directly to 16S ribosomal RNA
PMN2A_RS08340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PMN2A_RS08350	COG0195	Participates in both transcription termination and antitermination
PMN2A_RS08375	COG0302	gtp cyclohydrolase
PMN2A_RS08410	COG1121	(ABC) transporter
PMN2A_RS08425	COG0523	cobalamin synthesis protein
PMN2A_RS08485	COG0830	nickel cation binding
PMN2A_RS08490	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PMN2A_RS08505	COG0832	Belongs to the urease beta subunit family
PMN2A_RS08535	COG0724	RNA recognition motif
PMN2A_RS08550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PMN2A_RS08560	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PMN2A_RS08570	COG1530	ribonuclease E activity
PMN2A_RS08585	COG0077	Prephenate dehydratase
PMN2A_RS08585	COG1605	Chorismate mutase
PMN2A_RS08590	COG2226	methyltransferase
PMN2A_RS08595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PMN2A_RS08600	COG0051	transcription antitermination factor activity, RNA binding
PMN2A_RS08615	COG0049	tRNA binding
PMN2A_RS08625	COG0070	glutamate synthase
PMN2A_RS08625	COG0069	glutamate synthase activity
PMN2A_RS08625	COG0067	glutamate synthase
PMN2A_RS08635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PMN2A_RS08650	COG2885	chlorophyll binding
PMN2A_RS08670	COG0463	Glycosyl transferase, family 2
PMN2A_RS08750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PMN2A_RS08770	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PMN2A_RS08775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PMN2A_RS08780	COG0101	tRNA pseudouridine synthase activity
PMN2A_RS08785	COG0203	ribosomal protein L17
PMN2A_RS08790	COG0202	RNA polymerase activity
PMN2A_RS08810	COG0201	protein transport
PMN2A_RS08825	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PMN2A_RS08850	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PMN2A_RS08855	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PMN2A_RS08870	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PMN2A_RS08875	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PMN2A_RS08880	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PMN2A_RS08885	COG0089	rRNA binding
PMN2A_RS08945	COG3001	Fructosamine kinase
PMN2A_RS08965	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
PMN2A_RS08970	COG1606	tRNA processing
PMN2A_RS08975	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PMN2A_RS08980	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PMN2A_RS08995	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PMN2A_RS09000	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PMN2A_RS09005	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PMN2A_RS09020	COG0772	Belongs to the SEDS family
PMN2A_RS09025	COG0489	protein tyrosine kinase activity
PMN2A_RS09045	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PMN2A_RS09095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PMN2A_RS09110	COG5398	heme oxygenase
PMN2A_RS09115	COG0538	isocitrate dehydrogenase activity
PMN2A_RS09135	COG0596	Alpha beta hydrolase
PMN2A_RS09140	COG0475	glutathione-regulated potassium exporter activity
PMN2A_RS09145	COG0058	SHG alpha-glucan phosphorylase activity
PMN2A_RS09165	COG0571	ribonuclease III activity
PMN2A_RS09185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PMN2A_RS09190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PMN2A_RS09195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PMN2A_RS09200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PMN2A_RS09205	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PMN2A_RS09220	COG1473	amidohydrolase
PMN2A_RS09245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PMN2A_RS09250	COG0745	RESPONSE REGULATOR receiver
PMN2A_RS09270	COG0629	single-stranded DNA binding
PMN2A_RS09275	COG0586	Pfam SNARE associated Golgi protein
PMN2A_RS09285	COG0802	atpase or kinase
PMN2A_RS09305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PMN2A_RS09310	COG2239	Acts as a magnesium transporter
PMN2A_RS09315	COG0386	Belongs to the glutathione peroxidase family
PMN2A_RS09335	COG0187	DNA topoisomerase II activity
PMN2A_RS09335	COG1372	Participates in initiation and elongation during chromosome replication
PMN2A_RS09350	COG1725	Transcriptional regulator
PMN2A_RS09355	COG1045	serine acetyltransferase
PMN2A_RS09375	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
PMN2A_RS09415	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
PMN2A_RS09450	COG1086	Polysaccharide biosynthesis protein
PMN2A_RS09455	COG1088	dTDP-glucose 4,6-dehydratase activity
PMN2A_RS09505	COG2082	Precorrin-8x methylmutase
PMN2A_RS09535	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PMN2A_RS09545	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PMN2A_RS09560	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PMN2A_RS09565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PMN2A_RS09570	COG1215	transferase activity, transferring glycosyl groups
PMN2A_RS09580	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PMN2A_RS09585	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PMN2A_RS09605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PMN2A_RS09630	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
PMN2A_RS09650	COG1372	Participates in initiation and elongation during chromosome replication
PMN2A_RS09650	COG0305	Participates in initiation and elongation during chromosome replication
PMN2A_RS09650	COG0305	Participates in initiation and elongation during chromosome replication
PMN2A_RS09650	COG1372	Participates in initiation and elongation during chromosome replication
PMN2A_RS09685	COG0398	Pfam SNARE associated Golgi protein
PMN2A_RS09715	COG3956	TIGRFAM MazG family protein
PMN2A_RS09750	COG0602	queuosine metabolic process
PMN2A_RS09760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PMN2A_RS09765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PMN2A_RS09770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PMN2A_RS09785	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PMN2A_RS09790	COG2116	formate transmembrane transporter activity
PMN2A_RS09800	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PMN2A_RS09815	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PMN2A_RS09820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PMN2A_RS09825	COG0170	dolichyl monophosphate biosynthetic process
PMN2A_RS09830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PMN2A_RS09835	COG1049	propionate catabolic process, 2-methylcitrate cycle
PMN2A_RS09850	COG0788	formyltetrahydrofolate deformylase activity
PMN2A_RS09865	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PMN2A_RS09910	COG0438	transferase activity, transferring glycosyl groups
PMN2A_RS09915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PMN2A_RS09920	COG0497	DNA recombination
PMN2A_RS09925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PMN2A_RS09935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine