locus-tag	class	description
BAR1_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BAR1_RS00025	COG1335	isochorismatase
BAR1_RS00030	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BAR1_RS00040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BAR1_RS00050	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BAR1_RS00060	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BAR1_RS00080	COG0514	ATP-dependent DNA helicase (RecQ)
BAR1_RS00085	COG3022	response to hydroperoxide
BAR1_RS00090	COG2205	protein histidine kinase activity
BAR1_RS00090	COG0784	Response regulator, receiver
BAR1_RS00090	COG5002	protein histidine kinase activity
BAR1_RS00095	COG2373	Large extracellular alpha-helical protein
BAR1_RS00100	COG4953	penicillin-binding protein 1C
BAR1_RS00105	COG0183	Belongs to the thiolase family
BAR1_RS00110	COG1846	Transcriptional regulator
BAR1_RS00120	COG0625	glutathione transferase activity
BAR1_RS00125	COG0179	Fumarylacetoacetate (FAA) hydrolase
BAR1_RS00160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BAR1_RS00170	COG3830	Belongs to the UPF0237 family
BAR1_RS00170	COG0560	Phosphoserine phosphatase
BAR1_RS00185	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BAR1_RS00195	COG0709	Synthesizes selenophosphate from selenide and ATP
BAR1_RS00200	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BAR1_RS00205	COG2171	N-acyltransferase activity
BAR1_RS00220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAR1_RS00225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BAR1_RS00240	COG0557	exoribonuclease II activity
BAR1_RS00250	COG2378	regulation of single-species biofilm formation
BAR1_RS00255	COG2951	lytic endotransglycosylase activity
BAR1_RS00260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BAR1_RS00270	COG1051	belongs to the nudix hydrolase family
BAR1_RS00275	COG0793	Belongs to the peptidase S41A family
BAR1_RS00285	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BAR1_RS00295	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BAR1_RS00300	COG0799	negative regulation of ribosome biogenesis
BAR1_RS00305	COG0154	amidase activity
BAR1_RS00310	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BAR1_RS00310	COG3264	Mechanosensitive ion channel
BAR1_RS00315	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BAR1_RS00320	COG0066	3-isopropylmalate dehydratase activity
BAR1_RS00345	COG0473	3-isopropylmalate dehydrogenase activity
BAR1_RS00365	COG5598	trimethylamine methyltransferase
BAR1_RS00370	COG0446	pyridine nucleotide-disulphide oxidoreductase
BAR1_RS00370	COG1902	pentaerythritol trinitrate reductase activity
BAR1_RS00375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAR1_RS00380	COG0765	amino acid transport
BAR1_RS00385	COG1126	abc transporter atp-binding protein
BAR1_RS00400	COG3916	Acyl-homoserine-lactone synthase
BAR1_RS00420	COG0517	IMP dehydrogenase activity
BAR1_RS00420	COG4175	Glycine betaine
BAR1_RS00425	COG4176	ABC-type proline glycine betaine transport system permease component
BAR1_RS00440	COG0742	ribosomal rna small subunit methyltransferase
BAR1_RS00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BAR1_RS00475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BAR1_RS00480	COG1349	DNA-binding transcription factor activity
BAR1_RS00485	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BAR1_RS00490	COG0250	Participates in transcription elongation, termination and antitermination
BAR1_RS00495	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BAR1_RS00500	COG0081	regulation of translation
BAR1_RS00505	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BAR1_RS00510	COG0222	ribosome binding
BAR1_RS00515	COG0085	RNA polymerase activity
BAR1_RS00520	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BAR1_RS00525	COG0697	spore germination
BAR1_RS00535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BAR1_RS00540	COG0049	tRNA binding
BAR1_RS00545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BAR1_RS00550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BAR1_RS00555	COG0051	transcription antitermination factor activity, RNA binding
BAR1_RS00560	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BAR1_RS00565	COG0088	Forms part of the polypeptide exit tunnel
BAR1_RS00570	COG0089	rRNA binding
BAR1_RS00575	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BAR1_RS00580	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BAR1_RS00585	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BAR1_RS00590	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BAR1_RS00595	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BAR1_RS00600	COG0255	Belongs to the universal ribosomal protein uL29 family
BAR1_RS00605	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BAR1_RS00610	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BAR1_RS00615	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BAR1_RS00620	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BAR1_RS00625	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BAR1_RS00630	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BAR1_RS00635	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BAR1_RS00640	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BAR1_RS00645	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BAR1_RS00650	COG1841	ribosomal large subunit assembly
BAR1_RS00665	COG0200	Binds to the 23S rRNA
BAR1_RS00670	COG0201	protein transport
BAR1_RS00675	COG0563	adenylate kinase activity
BAR1_RS00680	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BAR1_RS00685	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BAR1_RS00690	COG0202	RNA polymerase activity
BAR1_RS00695	COG0203	ribosomal protein L17
BAR1_RS00715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BAR1_RS00725	COG0564	pseudouridine synthase activity
BAR1_RS00730	COG0546	phosphoglycolate phosphatase activity
BAR1_RS00740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAR1_RS00745	COG4597	amino acid ABC transporter
BAR1_RS00750	COG0765	amino acid transport
BAR1_RS00755	COG1126	abc transporter atp-binding protein
BAR1_RS00760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BAR1_RS00765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BAR1_RS00775	COG3842	ATPase activity
BAR1_RS00785	COG1177	transmembrane transport
BAR1_RS00790	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BAR1_RS00810	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BAR1_RS00815	COG1028	Short-chain dehydrogenase reductase Sdr
BAR1_RS00820	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BAR1_RS00830	COG0706	membrane insertase activity
BAR1_RS00835	COG5001	Diguanylate cyclase
BAR1_RS00840	COG0037	tRNA processing
BAR1_RS00845	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BAR1_RS00850	COG0594	ribonuclease P activity
BAR1_RS00855	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BAR1_RS00865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BAR1_RS00880	COG0842	Transport permease protein
BAR1_RS00885	COG0842	Transport permease protein
BAR1_RS00885	COG1129	ABC transporter
BAR1_RS00890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BAR1_RS00900	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BAR1_RS00920	COG0398	Pfam SNARE associated Golgi protein
BAR1_RS00965	COG2897	thiosulfate sulfurtransferase activity
BAR1_RS00975	COG0583	DNA-binding transcription factor activity
BAR1_RS00985	COG0004	ammonium transporteR
BAR1_RS01000	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BAR1_RS01005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BAR1_RS01025	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BAR1_RS01030	COG4143	(ABC) transporter
BAR1_RS01040	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BAR1_RS01055	COG0723	plastoquinol--plastocyanin reductase activity
BAR1_RS01075	COG0730	response to heat
BAR1_RS01090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BAR1_RS01095	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BAR1_RS01100	COG0235	Class ii aldolase
BAR1_RS01110	COG0395	ABC-type sugar transport system, permease component
BAR1_RS01115	COG1175	transmembrane transport
BAR1_RS01125	COG3842	ATPase activity
BAR1_RS01145	COG1070	Carbohydrate kinase
BAR1_RS01160	COG0698	ribose 5-phosphate isomerase
BAR1_RS01170	COG3791	Glutathione-dependent formaldehyde-activating
BAR1_RS01185	COG0784	Response regulator, receiver
BAR1_RS01185	COG2205	protein histidine kinase activity
BAR1_RS01220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BAR1_RS01225	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BAR1_RS01230	COG0535	radical SAM domain protein
BAR1_RS01235	COG0535	radical SAM domain protein
BAR1_RS01240	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BAR1_RS01245	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BAR1_RS01315	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAR1_RS01335	COG1129	ABC transporter
BAR1_RS01345	COG3842	ATPase activity
BAR1_RS01355	COG1175	transmembrane transport
BAR1_RS01360	COG0395	ABC-type sugar transport system, permease component
BAR1_RS01380	COG0179	Fumarylacetoacetate (FAA) hydrolase
BAR1_RS01390	COG2116	formate transmembrane transporter activity
BAR1_RS01395	COG2146	nitrite reductase [NAD(P)H] activity
BAR1_RS01400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BAR1_RS01405	COG0583	DNA-binding transcription factor activity
BAR1_RS01410	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BAR1_RS01415	COG0830	nickel cation binding
BAR1_RS01420	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BAR1_RS01430	COG0804	urea catabolic process
BAR1_RS01440	COG0832	Belongs to the urease beta subunit family
BAR1_RS01445	COG0831	urea catabolic process
BAR1_RS01450	COG0829	nickel cation binding
BAR1_RS01455	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BAR1_RS01460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BAR1_RS01465	COG0741	lytic transglycosylase activity
BAR1_RS01475	COG2853	Lipoprotein
BAR1_RS01485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BAR1_RS01495	COG0584	glycerophosphoryl diester phosphodiesterase
BAR1_RS01505	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BAR1_RS01515	COG1160	GTP binding
BAR1_RS01530	COG1609	Transcriptional regulator
BAR1_RS01545	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BAR1_RS01550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BAR1_RS01575	COG1858	cytochrome C peroxidase
BAR1_RS01590	COG0243	molybdopterin cofactor binding
BAR1_RS01605	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BAR1_RS01615	COG0535	radical SAM domain protein
BAR1_RS01625	COG0745	RESPONSE REGULATOR receiver
BAR1_RS01635	COG0778	Nitroreductase
BAR1_RS01650	COG0109	protoheme IX farnesyltransferase activity
BAR1_RS01705	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BAR1_RS01725	COG2197	response regulator
BAR1_RS01750	COG0318	PFAM AMP-dependent synthetase and ligase
BAR1_RS01765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BAR1_RS01780	COG0446	pyridine nucleotide-disulphide oxidoreductase
BAR1_RS01785	COG2863	cytochrome
BAR1_RS01795	COG4181	ATPase activity
BAR1_RS01805	COG1024	Enoyl-CoA hydratase
BAR1_RS01815	COG1960	acyl-CoA dehydrogenase activity
BAR1_RS01820	COG0824	Thioesterase
BAR1_RS01820	COG1250	3-hydroxyacyl-CoA dehydrogenase
BAR1_RS01825	COG3246	L-lysine catabolic process to acetate
BAR1_RS01840	COG0601	transmembrane transport
BAR1_RS01845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAR1_RS01850	COG4172	Belongs to the ABC transporter superfamily
BAR1_RS01870	COG0582	viral genome integration into host DNA
BAR1_RS01885	COG1968	undecaprenyl-diphosphatase activity
BAR1_RS01910	COG4991	sh3 domain protein
BAR1_RS01910	COG0860	N-Acetylmuramoyl-L-alanine amidase
BAR1_RS01910	COG3103	Sh3 type 3 domain protein
BAR1_RS01935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BAR1_RS01950	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BAR1_RS01955	COG0142	geranyltranstransferase activity
BAR1_RS01980	COG0583	DNA-binding transcription factor activity
BAR1_RS02000	COG2200	EAL domain
BAR1_RS02005	COG2818	Glycosylase
BAR1_RS02010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BAR1_RS02015	COG0165	Argininosuccinate lyase
BAR1_RS02030	COG1309	transcriptional regulator
BAR1_RS02040	COG0019	diaminopimelate decarboxylase activity
BAR1_RS02055	COG2884	Cell division ATP-binding protein ftsE
BAR1_RS02110	COG2301	Belongs to the HpcH HpaI aldolase family
BAR1_RS02120	COG4948	Mandelate Racemase Muconate Lactonizing
BAR1_RS02150	COG0469	pyruvate kinase activity
BAR1_RS02160	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BAR1_RS02165	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BAR1_RS02170	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BAR1_RS02185	COG0072	phenylalanine-tRNA ligase activity
BAR1_RS02185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BAR1_RS02210	COG0625	glutathione transferase activity
BAR1_RS02215	COG1970	mechanosensitive ion channel activity
BAR1_RS02220	COG0686	Belongs to the AlaDH PNT family
BAR1_RS02230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BAR1_RS02240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BAR1_RS02245	COG2151	metal-sulfur cluster biosynthetic enzyme
BAR1_RS02250	COG3396	Phenylacetate-CoA oxygenase
BAR1_RS02255	COG3460	Phenylacetate-CoA oxygenase
BAR1_RS02260	COG3396	Phenylacetate-CoA oxygenase
BAR1_RS02275	COG0138	bifunctional purine biosynthesis protein purh
BAR1_RS02280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BAR1_RS02290	COG0612	Peptidase, M16
BAR1_RS02295	COG0612	Peptidase, M16
BAR1_RS02300	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BAR1_RS02315	COG2084	Dehydrogenase
BAR1_RS02345	COG0559	Belongs to the binding-protein-dependent transport system permease family
BAR1_RS02365	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BAR1_RS02375	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BAR1_RS02395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BAR1_RS02415	COG0284	orotidine-5'-phosphate decarboxylase activity
BAR1_RS02425	COG0542	response to heat
BAR1_RS02435	COG0500	methyltransferase
BAR1_RS02450	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BAR1_RS02455	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BAR1_RS02515	COG0446	pyridine nucleotide-disulphide oxidoreductase
BAR1_RS02520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BAR1_RS02540	COG0768	penicillin binding
BAR1_RS02545	COG0772	Belongs to the SEDS family
BAR1_RS02575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BAR1_RS02585	COG1573	uracil-dna glycosylase
BAR1_RS02605	COG2212	antiporter activity
BAR1_RS02615	COG2111	Na H antiporter
BAR1_RS02615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BAR1_RS02625	COG1006	Multisubunit Na H antiporter MnhC subunit
BAR1_RS02630	COG0651	ATP synthesis coupled electron transport
BAR1_RS02635	COG0651	ATP synthesis coupled electron transport
BAR1_RS02645	COG0651	ATP synthesis coupled electron transport
BAR1_RS02660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BAR1_RS02705	COG1477	protein flavinylation
BAR1_RS02710	COG0842	Transport permease protein
BAR1_RS02715	COG1131	(ABC) transporter
BAR1_RS02725	COG1309	transcriptional regulator
BAR1_RS02735	COG0701	Predicted permease
BAR1_RS02750	COG0789	Transcriptional regulator
BAR1_RS02760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BAR1_RS02770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BAR1_RS02780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BAR1_RS02795	COG0346	lactoylglutathione lyase activity
BAR1_RS02810	COG0778	Nitroreductase
BAR1_RS02830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BAR1_RS02835	COG0142	geranyltranstransferase activity
BAR1_RS02840	COG1722	exodeoxyribonuclease VII activity
BAR1_RS02845	COG0123	including yeast histone deacetylase and acetoin utilization protein
BAR1_RS02860	COG2223	nitrite transmembrane transporter activity
BAR1_RS02865	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BAR1_RS02870	COG1140	nitrate reductase beta subunit
BAR1_RS02875	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BAR1_RS02880	COG2181	nitrate reductase activity
BAR1_RS02885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BAR1_RS02905	COG0745	RESPONSE REGULATOR receiver
BAR1_RS02910	COG1846	Transcriptional regulator
BAR1_RS02915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BAR1_RS02935	COG1872	DUF167
BAR1_RS02960	COG1331	Highly conserved protein containing a thioredoxin domain
BAR1_RS02975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BAR1_RS03000	COG0390	transport system, permease component
BAR1_RS03005	COG1116	anion transmembrane transporter activity
BAR1_RS03010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BAR1_RS03015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BAR1_RS03030	COG0488	(ABC) transporter
BAR1_RS03040	COG0667	Aldo Keto reductase
BAR1_RS03045	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BAR1_RS03065	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BAR1_RS03070	COG0500	methyltransferase
BAR1_RS03110	COG0556	nucleotide-excision repair
BAR1_RS03135	COG0640	Transcriptional regulator
BAR1_RS03170	COG3258	Cytochrome c
BAR1_RS03175	COG0737	Belongs to the 5'-nucleotidase family
BAR1_RS03180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BAR1_RS03190	COG3474	cytochrome
BAR1_RS03195	COG0446	pyridine nucleotide-disulphide oxidoreductase
BAR1_RS03220	COG3246	L-lysine catabolic process to acetate
BAR1_RS03225	COG3485	protocatechuate 3,4-dioxygenase
BAR1_RS03230	COG3485	protocatechuate 3,4-dioxygenase
BAR1_RS03235	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BAR1_RS03280	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BAR1_RS03290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BAR1_RS03295	COG0735	belongs to the Fur family
BAR1_RS03315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BAR1_RS03320	COG1702	phosphate starvation-inducible protein PhoH
BAR1_RS03325	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BAR1_RS03330	COG1253	flavin adenine dinucleotide binding
BAR1_RS03335	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BAR1_RS03340	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BAR1_RS03345	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BAR1_RS03350	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BAR1_RS03380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BAR1_RS03390	COG0539	negative regulation of cytoplasmic translation
BAR1_RS03395	COG0776	regulation of translation
BAR1_RS03410	COG0133	tryptophan synthase activity
BAR1_RS03430	COG1132	(ABC) transporter
BAR1_RS03435	COG0318	PFAM AMP-dependent synthetase and ligase
BAR1_RS03465	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BAR1_RS03465	COG0546	phosphoglycolate phosphatase activity
BAR1_RS03470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BAR1_RS03480	COG0277	FAD linked oxidase domain protein
BAR1_RS03510	COG1309	transcriptional regulator
BAR1_RS03515	COG1754	DNA topoisomerase type I activity
BAR1_RS03515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BAR1_RS03520	COG0758	DNA mediated transformation
BAR1_RS03535	COG0312	modulator of DNA gyrase
BAR1_RS03555	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BAR1_RS03565	COG3346	SURF1 family
BAR1_RS03575	COG0612	Peptidase, M16
BAR1_RS03595	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BAR1_RS03605	COG0012	GTP binding
BAR1_RS03615	COG0159	tryptophan synthase activity
BAR1_RS03625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BAR1_RS03660	COG1304	FMN binding
BAR1_RS03665	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BAR1_RS03690	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BAR1_RS03695	COG3257	ureidoglycine aminohydrolase activity
BAR1_RS03705	COG2351	hydroxyisourate hydrolase activity
BAR1_RS03710	COG0583	DNA-binding transcription factor activity
BAR1_RS03725	COG1121	(ABC) transporter
BAR1_RS03730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BAR1_RS03740	COG0437	4 iron, 4 sulfur cluster binding
BAR1_RS03745	COG0243	molybdopterin cofactor binding
BAR1_RS03750	COG0372	Belongs to the citrate synthase family
BAR1_RS03760	COG0028	Belongs to the TPP enzyme family
BAR1_RS03765	COG1794	racemase activity, acting on amino acids and derivatives
BAR1_RS03775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BAR1_RS03780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BAR1_RS03785	COG0174	glutamine synthetase
BAR1_RS03790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BAR1_RS03790	COG0519	Catalyzes the synthesis of GMP from XMP
BAR1_RS03795	COG0174	glutamine synthetase
BAR1_RS03830	COG0504	CTP synthase activity
BAR1_RS03845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BAR1_RS03890	COG1760	l-serine dehydratase
BAR1_RS03900	COG1846	Transcriptional regulator
BAR1_RS03905	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BAR1_RS03920	COG0330	HflC and HflK could
BAR1_RS03935	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BAR1_RS03955	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BAR1_RS03960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BAR1_RS03975	COG0525	valine-tRNA ligase activity
BAR1_RS04000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BAR1_RS04005	COG0583	DNA-binding transcription factor activity
BAR1_RS04015	COG0483	inositol monophosphate 1-phosphatase activity
BAR1_RS04045	COG1522	sequence-specific DNA binding
BAR1_RS04055	COG4122	O-methyltransferase activity
BAR1_RS04070	COG0174	glutamine synthetase
BAR1_RS04105	COG0745	RESPONSE REGULATOR receiver
BAR1_RS04110	COG2205	protein histidine kinase activity
BAR1_RS04135	COG1850	ribulose-bisphosphate carboxylase activity
BAR1_RS04145	COG0126	phosphoglycerate kinase activity
BAR1_RS04165	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BAR1_RS04175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BAR1_RS04180	COG1960	acyl-CoA dehydrogenase activity
BAR1_RS04185	COG0028	Belongs to the TPP enzyme family
BAR1_RS04195	COG0740	serine-type endopeptidase activity
BAR1_RS04200	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BAR1_RS04230	COG0439	Biotin carboxylase
BAR1_RS04235	COG0511	ligase activity, forming carbon-carbon bonds
BAR1_RS04240	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BAR1_RS04240	COG0493	'glutamate synthase
BAR1_RS04255	COG1309	transcriptional regulator
BAR1_RS04260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BAR1_RS04285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BAR1_RS04290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BAR1_RS04295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BAR1_RS04300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BAR1_RS04305	COG0410	ABC transporter
BAR1_RS04375	COG3750	Belongs to the UPF0335 family
BAR1_RS04390	COG0395	ABC-type sugar transport system, permease component
BAR1_RS04505	COG0508	dehydrogenase complex catalyzes the overall conversion of
BAR1_RS04505	COG0022	dehydrogenase e1 component
BAR1_RS04510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BAR1_RS04520	COG0577	efflux transmembrane transporter activity
BAR1_RS04520	COG1136	(ABC) transporter
BAR1_RS04550	COG1309	transcriptional regulator
BAR1_RS04570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BAR1_RS04580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BAR1_RS04585	COG5328	Belongs to the UPF0262 family
BAR1_RS04595	COG0071	Belongs to the small heat shock protein (HSP20) family
BAR1_RS04615	COG3853	Toxic anion resistance protein (TelA)
BAR1_RS04625	COG0861	Integral membrane protein TerC family
BAR1_RS04630	COG1187	pseudouridine synthase activity
BAR1_RS04635	COG0590	tRNA wobble adenosine to inosine editing
BAR1_RS04640	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BAR1_RS04645	COG0154	amidase activity
BAR1_RS04655	COG3023	N-Acetylmuramoyl-L-alanine amidase
BAR1_RS04675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BAR1_RS04685	COG0670	Belongs to the BI1 family
BAR1_RS04695	COG0583	DNA-binding transcription factor activity
BAR1_RS04730	COG2391	methyltransferase activity
BAR1_RS04735	COG1648	precorrin-2 dehydrogenase activity
BAR1_RS04735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BAR1_RS04755	COG2221	Nitrite and sulphite reductase 4Fe-4S
BAR1_RS04760	COG2221	Nitrite and sulphite reductase 4Fe-4S
BAR1_RS04765	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BAR1_RS04770	COG2923	Belongs to the DsrF TusC family
BAR1_RS04780	COG2920	part of a sulfur-relay system
BAR1_RS04815	COG1797	cobyrinic acid a,c-diamide synthase activity
BAR1_RS04820	COG0425	Belongs to the sulfur carrier protein TusA family
BAR1_RS04825	COG2210	Belongs to the sulfur carrier protein TusA family
BAR1_RS04845	COG1840	ABC-type Fe3 transport system, periplasmic component
BAR1_RS04890	COG4176	ABC-type proline glycine betaine transport system permease component
BAR1_RS04915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BAR1_RS04970	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BAR1_RS04975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BAR1_RS04995	COG0564	pseudouridine synthase activity
BAR1_RS05005	COG3152	Membrane
BAR1_RS05065	COG1960	acyl-CoA dehydrogenase activity
BAR1_RS05070	COG3755	Protein conserved in bacteria
BAR1_RS05090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BAR1_RS05095	COG2070	2-Nitropropane dioxygenase
BAR1_RS05100	COG4770	biotin carboxylase activity
BAR1_RS05130	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BAR1_RS05140	COG0649	NAD binding
BAR1_RS05190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BAR1_RS05195	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BAR1_RS05205	COG0713	ATP synthesis coupled electron transport
BAR1_RS05230	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BAR1_RS05240	COG0513	Belongs to the DEAD box helicase family
BAR1_RS05245	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BAR1_RS05250	COG4172	Belongs to the ABC transporter superfamily
BAR1_RS05260	COG1028	Short-chain dehydrogenase reductase Sdr
BAR1_RS05265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BAR1_RS05270	COG2226	methyltransferase
BAR1_RS05275	COG3842	ATPase activity
BAR1_RS05300	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BAR1_RS05325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BAR1_RS05350	COG0175	sulfate reduction
BAR1_RS05355	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BAR1_RS05360	COG2124	cytochrome p450
BAR1_RS05375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BAR1_RS05380	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BAR1_RS05385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BAR1_RS05390	COG0149	triose-phosphate isomerase activity
BAR1_RS05405	COG0316	Belongs to the HesB IscA family
BAR1_RS05410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BAR1_RS05415	COG2151	metal-sulfur cluster biosynthetic enzyme
BAR1_RS05420	COG1301	dicarboxylic acid transport
BAR1_RS05435	COG2081	HI0933 family
BAR1_RS05445	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BAR1_RS05450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BAR1_RS05455	COG0531	amino acid
BAR1_RS05475	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BAR1_RS05480	COG1181	Belongs to the D-alanine--D-alanine ligase family
BAR1_RS05485	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BAR1_RS05495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BAR1_RS05505	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BAR1_RS05520	COG0277	FAD linked oxidase domain protein
BAR1_RS05540	COG1994	Peptidase M50
BAR1_RS05540	COG0517	IMP dehydrogenase activity
BAR1_RS05575	COG0484	heat shock protein binding
BAR1_RS05590	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BAR1_RS05605	COG1028	Short-chain dehydrogenase reductase Sdr
BAR1_RS05610	COG0308	aminopeptidase N
BAR1_RS05675	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BAR1_RS05680	COG0789	Transcriptional regulator
BAR1_RS05695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAR1_RS05700	COG0601	transmembrane transport
BAR1_RS05705	COG4166	transmembrane transport
BAR1_RS05710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BAR1_RS05715	COG1473	amidohydrolase
BAR1_RS05720	COG0519	Catalyzes the synthesis of GMP from XMP
BAR1_RS05720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BAR1_RS05725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BAR1_RS05735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BAR1_RS05750	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BAR1_RS05755	COG0546	phosphoglycolate phosphatase activity
BAR1_RS05765	COG2379	hydroxypyruvate reductase
BAR1_RS05785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BAR1_RS05790	COG0730	response to heat
BAR1_RS05795	COG2378	regulation of single-species biofilm formation
BAR1_RS05800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BAR1_RS05810	COG0805	protein transport
BAR1_RS05820	COG0741	lytic transglycosylase activity
BAR1_RS05820	COG1388	LysM domain
BAR1_RS05830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BAR1_RS05835	COG4221	oxidoreductase activity
BAR1_RS05845	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BAR1_RS05870	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BAR1_RS05875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BAR1_RS05895	COG0305	Participates in initiation and elongation during chromosome replication
BAR1_RS05905	COG0418	dihydroorotase activity
BAR1_RS05920	COG1280	lysine exporter protein (LysE YggA)
BAR1_RS05925	COG1960	acyl-CoA dehydrogenase activity
BAR1_RS05940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BAR1_RS05950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BAR1_RS05965	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BAR1_RS05965	COG0446	pyridine nucleotide-disulphide oxidoreductase
BAR1_RS06030	COG5265	(ABC) transporter
BAR1_RS06040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BAR1_RS06060	COG1160	GTP binding
BAR1_RS06075	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BAR1_RS06080	COG1862	Preprotein translocase
BAR1_RS06085	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BAR1_RS06090	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BAR1_RS06105	COG3737	Protein of unknown function (DUF498/DUF598)
BAR1_RS06110	COG4133	protoheme IX ABC transporter activity
BAR1_RS06115	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BAR1_RS06120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BAR1_RS06130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BAR1_RS06135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BAR1_RS06190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BAR1_RS06195	COG1268	BioY protein
BAR1_RS06205	COG1073	alpha beta
BAR1_RS06235	COG2132	Multicopper oxidase
BAR1_RS06240	COG0702	epimerase
BAR1_RS06275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BAR1_RS06290	COG0544	peptidyl-prolyl cis-trans isomerase activity
BAR1_RS06300	COG0359	binds to the 23S rRNA
BAR1_RS06305	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BAR1_RS06310	COG0360	Binds together with S18 to 16S ribosomal RNA
BAR1_RS06325	COG3038	cytochrome b561
BAR1_RS06330	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BAR1_RS06345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BAR1_RS06360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BAR1_RS06365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BAR1_RS06405	COG0508	dehydrogenase complex catalyzes the overall conversion of
BAR1_RS06410	COG0508	dehydrogenase complex catalyzes the overall conversion of
BAR1_RS06410	COG0022	dehydrogenase e1 component
BAR1_RS06415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BAR1_RS06420	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BAR1_RS06425	COG1830	Aldolase
BAR1_RS06430	COG0126	phosphoglycerate kinase activity
BAR1_RS06455	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BAR1_RS06460	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BAR1_RS06480	COG0148	phosphopyruvate hydratase activity
BAR1_RS06485	COG0697	spore germination
BAR1_RS06500	COG2920	part of a sulfur-relay system
BAR1_RS06525	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BAR1_RS06530	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BAR1_RS06585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BAR1_RS06585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BAR1_RS06595	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BAR1_RS06600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BAR1_RS06640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BAR1_RS06645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BAR1_RS06650	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BAR1_RS06660	COG2166	iron-sulfur cluster assembly
BAR1_RS06670	COG5012	cobalamin binding
BAR1_RS06675	COG1410	methionine synthase
BAR1_RS06675	COG0646	methionine synthase
BAR1_RS06680	COG0392	lysyltransferase activity
BAR1_RS06690	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BAR1_RS06695	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BAR1_RS06700	COG0047	phosphoribosylformylglycinamidine synthase activity
BAR1_RS06710	COG2204	response regulator
BAR1_RS06715	COG1530	ribonuclease E activity
BAR1_RS06720	COG0425	Belongs to the sulfur carrier protein TusA family
BAR1_RS06725	COG0785	Cytochrome C biogenesis protein
BAR1_RS06755	COG0114	fumarate hydratase activity
BAR1_RS06765	COG2059	Chromate
BAR1_RS06795	COG3738	Protein conserved in bacteria
BAR1_RS06825	COG2186	Transcriptional regulator
BAR1_RS06840	COG0604	alcohol dehydrogenase
BAR1_RS06860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BAR1_RS06870	COG0494	nUDIX hydrolase
BAR1_RS06880	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BAR1_RS06880	COG3264	Mechanosensitive ion channel
BAR1_RS06910	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BAR1_RS06915	COG0019	diaminopimelate decarboxylase activity
BAR1_RS06995	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BAR1_RS07005	COG1475	DNA binding
BAR1_RS07035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BAR1_RS07040	COG0318	PFAM AMP-dependent synthetase and ligase
BAR1_RS07055	COG4172	Belongs to the ABC transporter superfamily
BAR1_RS07060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAR1_RS07065	COG0601	transmembrane transport
BAR1_RS07075	COG1414	Transcriptional regulator
BAR1_RS07090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BAR1_RS07100	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BAR1_RS07135	COG2205	protein histidine kinase activity
BAR1_RS07140	COG0745	RESPONSE REGULATOR receiver
BAR1_RS07145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BAR1_RS07155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BAR1_RS07160	COG1830	Aldolase
BAR1_RS07165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BAR1_RS07180	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAR1_RS07195	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BAR1_RS07200	COG2390	Transcriptional regulator
BAR1_RS07205	COG1028	Short-chain dehydrogenase reductase Sdr
BAR1_RS07205	COG3347	Dehydrogenase
BAR1_RS07210	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BAR1_RS07215	COG3383	formate dehydrogenase (NAD+) activity
BAR1_RS07220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BAR1_RS07230	COG0488	(ABC) transporter
BAR1_RS07285	COG1183	phosphatidylcholine synthase activity
BAR1_RS07290	COG0688	phosphatidylethanolamine metabolic process
BAR1_RS07300	COG2194	sulfuric ester hydrolase activity
BAR1_RS07310	COG0215	cysteine-tRNA ligase activity
BAR1_RS07315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BAR1_RS07325	COG2814	Major facilitator Superfamily
BAR1_RS07330	COG1797	cobyrinic acid a,c-diamide synthase activity
BAR1_RS07355	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BAR1_RS07360	COG2099	Precorrin-6x reductase
BAR1_RS07365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BAR1_RS07400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BAR1_RS07440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BAR1_RS07445	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BAR1_RS07470	COG1410	methionine synthase
BAR1_RS07470	COG0646	methionine synthase
BAR1_RS07475	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BAR1_RS07485	COG0248	Ppx GppA phosphatase
BAR1_RS07490	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BAR1_RS07500	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BAR1_RS07520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BAR1_RS07525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BAR1_RS07615	COG3436	PFAM IS66 Orf2 family protein
BAR1_RS07650	COG1489	DNA binding
BAR1_RS07660	COG1489	DNA binding
BAR1_RS07770	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BAR1_RS07770	COG3743	rRNA binding
BAR1_RS07775	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BAR1_RS07785	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BAR1_RS07790	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BAR1_RS07795	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BAR1_RS07825	COG2226	methyltransferase
BAR1_RS07835	COG0194	GDP metabolic process
BAR1_RS07840	COG1561	YicC-like family, N-terminal region
BAR1_RS07850	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BAR1_RS07895	COG0626	cystathionine gamma-synthase activity
BAR1_RS07905	COG5002	protein histidine kinase activity
BAR1_RS07915	COG0573	inorganic phosphate transmembrane transporter activity
BAR1_RS07925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BAR1_RS07935	COG0745	RESPONSE REGULATOR receiver
BAR1_RS07950	COG4589	Belongs to the CDS family
BAR1_RS07960	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BAR1_RS07970	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BAR1_RS07980	COG2197	response regulator
BAR1_RS07985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BAR1_RS08000	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BAR1_RS08005	COG2771	luxR family
BAR1_RS08010	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BAR1_RS08015	COG0052	Belongs to the universal ribosomal protein uS2 family
BAR1_RS08035	COG2313	pseudouridylate synthase activity
BAR1_RS08065	COG4166	transmembrane transport
BAR1_RS08095	COG2271	Major facilitator Superfamily
BAR1_RS08100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BAR1_RS08120	COG2084	Dehydrogenase
BAR1_RS08125	COG2366	antibiotic biosynthetic process
BAR1_RS08130	COG0435	Glutathione S-transferase
BAR1_RS08135	COG1741	Belongs to the pirin family
BAR1_RS08140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BAR1_RS08150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BAR1_RS08155	COG0569	domain protein
BAR1_RS08160	COG2204	response regulator
BAR1_RS08165	COG5000	phosphorelay sensor kinase activity
BAR1_RS08170	COG2204	response regulator
BAR1_RS08175	COG3852	Histidine kinase
BAR1_RS08180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BAR1_RS08185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BAR1_RS08185	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BAR1_RS08195	COG1546	Belongs to the CinA family
BAR1_RS08200	COG2867	negative regulation of translational initiation
BAR1_RS08205	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BAR1_RS08225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BAR1_RS08245	COG2010	Cytochrome c
BAR1_RS08250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BAR1_RS08270	COG0753	catalase activity
BAR1_RS08300	COG0697	spore germination
BAR1_RS08310	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BAR1_RS08315	COG2326	polyphosphate kinase activity
BAR1_RS08320	COG1309	transcriptional regulator
BAR1_RS08330	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BAR1_RS08335	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BAR1_RS08340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BAR1_RS08355	COG1024	Enoyl-CoA hydratase
BAR1_RS08375	COG1083	cytidylyl-transferase
BAR1_RS08380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BAR1_RS08390	COG1612	heme a metabolic process
BAR1_RS08400	COG0352	thiamine-phosphate diphosphorylase activity
BAR1_RS08410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BAR1_RS08420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BAR1_RS08445	COG3842	ATPase activity
BAR1_RS08455	COG0395	ABC-type sugar transport system, permease component
BAR1_RS08460	COG1175	transmembrane transport
BAR1_RS08470	COG1609	Transcriptional regulator
BAR1_RS08475	COG0574	Belongs to the PEP-utilizing enzyme family
BAR1_RS08475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BAR1_RS08480	COG0385	Bile acid
BAR1_RS08485	COG1999	signal sequence binding
BAR1_RS08490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BAR1_RS08510	COG0348	domain, Protein
BAR1_RS08515	COG0437	4 iron, 4 sulfur cluster binding
BAR1_RS08540	COG4263	nitrous-oxide reductase activity
BAR1_RS08550	COG2226	methyltransferase
BAR1_RS08565	COG1733	regulation of RNA biosynthetic process
BAR1_RS08575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BAR1_RS08580	COG0489	protein tyrosine kinase activity
BAR1_RS08595	COG3474	cytochrome
BAR1_RS08600	COG0243	molybdopterin cofactor binding
BAR1_RS08605	COG0437	4 iron, 4 sulfur cluster binding
BAR1_RS08625	COG3604	Transcriptional regulator
BAR1_RS08630	COG0133	tryptophan synthase activity
BAR1_RS08640	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BAR1_RS08680	COG2321	neutral zinc metallopeptidase
BAR1_RS08690	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BAR1_RS08715	COG2423	ornithine cyclodeaminase activity
BAR1_RS08720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BAR1_RS08725	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BAR1_RS08730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BAR1_RS08750	COG0840	transmembrane signaling receptor activity
BAR1_RS08760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BAR1_RS08775	COG0482	sulfurtransferase activity
BAR1_RS08780	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BAR1_RS08785	COG3494	Protein of unknown function (DUF1009)
BAR1_RS08790	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BAR1_RS08795	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BAR1_RS08805	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BAR1_RS08810	COG0750	zinc metalloprotease
BAR1_RS08815	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BAR1_RS08825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BAR1_RS08830	COG0233	cytoplasmic translational termination
BAR1_RS08840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BAR1_RS08850	COG0346	lactoylglutathione lyase activity
BAR1_RS08855	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BAR1_RS08860	COG0741	lytic transglycosylase activity
BAR1_RS08865	COG0629	single-stranded DNA binding
BAR1_RS08870	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BAR1_RS08875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BAR1_RS08885	COG4974	Belongs to the 'phage' integrase family
BAR1_RS08890	COG4536	flavin adenine dinucleotide binding
BAR1_RS08900	COG0433	COG0433 Predicted ATPase
BAR1_RS08910	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BAR1_RS08915	COG2989	Protein conserved in bacteria
BAR1_RS08925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BAR1_RS08925	COG2755	lipolytic protein G-D-S-L family
BAR1_RS08930	COG2755	lipolytic protein G-D-S-L family
BAR1_RS08930	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BAR1_RS08940	COG0022	dehydrogenase e1 component
BAR1_RS08955	COG1012	belongs to the aldehyde dehydrogenase family
BAR1_RS09110	COG4227	nucleotidyltransferase activity
BAR1_RS09145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BAR1_RS09235	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BAR1_RS09245	COG0719	Fe-S assembly protein
BAR1_RS09250	COG0396	ATPase activity
BAR1_RS09265	COG0719	Fe-S assembly protein
BAR1_RS09280	COG2945	thiolester hydrolase activity
BAR1_RS09290	COG0538	isocitrate dehydrogenase activity
BAR1_RS09295	COG1217	gtp-binding protein TYPA
BAR1_RS09330	COG1522	sequence-specific DNA binding
BAR1_RS09345	COG0105	UTP biosynthetic process
BAR1_RS09350	COG0488	(ABC) transporter
BAR1_RS09355	COG2095	MarC family integral membrane protein
BAR1_RS09370	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BAR1_RS09375	COG0795	lipopolysaccharide-transporting ATPase activity
BAR1_RS09385	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BAR1_RS09395	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BAR1_RS09400	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BAR1_RS09410	COG2890	protein-(glutamine-N5) methyltransferase activity
BAR1_RS09415	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BAR1_RS09430	COG0010	Belongs to the arginase family
BAR1_RS09435	COG1473	amidohydrolase
BAR1_RS09440	COG3956	TIGRFAM MazG family protein
BAR1_RS09445	COG1840	ABC-type Fe3 transport system, periplasmic component
BAR1_RS09455	COG0010	Belongs to the arginase family
BAR1_RS09495	COG0745	RESPONSE REGULATOR receiver
BAR1_RS09500	COG2198	Histidine kinase
BAR1_RS09500	COG0643	Histidine kinase
BAR1_RS09505	COG0835	chemotaxis
BAR1_RS09510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BAR1_RS09515	COG0745	RESPONSE REGULATOR receiver
BAR1_RS09525	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BAR1_RS09530	COG0840	transmembrane signaling receptor activity
BAR1_RS09545	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BAR1_RS09550	COG0416	fatty acid biosynthetic process
BAR1_RS09555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BAR1_RS09560	COG0776	regulation of translation
BAR1_RS09575	COG0717	Belongs to the dCTP deaminase family
BAR1_RS09585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BAR1_RS09590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BAR1_RS09605	COG0018	arginyl-trna synthetase
BAR1_RS09610	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BAR1_RS09615	COG0316	Belongs to the HesB IscA family
BAR1_RS09650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BAR1_RS09695	COG1054	Belongs to the UPF0176 family
BAR1_RS09705	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BAR1_RS09715	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BAR1_RS09735	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BAR1_RS09750	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BAR1_RS09775	COG0028	Belongs to the TPP enzyme family
BAR1_RS09810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BAR1_RS09825	COG1278	Cold shock
BAR1_RS09830	COG0259	pyridoxamine-phosphate oxidase activity
BAR1_RS09835	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BAR1_RS09840	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BAR1_RS09855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BAR1_RS09875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BAR1_RS09885	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BAR1_RS09915	COG0303	'Molybdopterin
BAR1_RS09930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BAR1_RS09940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BAR1_RS09945	COG0372	Belongs to the citrate synthase family
BAR1_RS09950	COG1024	Enoyl-CoA hydratase
BAR1_RS09955	COG3088	subunit of a heme lyase
BAR1_RS09960	COG1138	Cytochrome C-type biogenesis protein
BAR1_RS09980	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BAR1_RS09985	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BAR1_RS10010	COG4941	Belongs to the sigma-70 factor family
BAR1_RS10015	COG3795	YCII-related domain
BAR1_RS10025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BAR1_RS10030	COG0271	Belongs to the BolA IbaG family
BAR1_RS10040	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BAR1_RS10060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BAR1_RS10075	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BAR1_RS10085	COG0583	DNA-binding transcription factor activity
BAR1_RS10100	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BAR1_RS10105	COG1960	acyl-CoA dehydrogenase activity
BAR1_RS10120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BAR1_RS10130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BAR1_RS10145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BAR1_RS10155	COG2814	Major facilitator Superfamily
BAR1_RS10160	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BAR1_RS10175	COG0739	heme binding
BAR1_RS10195	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BAR1_RS10200	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BAR1_RS10205	COG0860	N-Acetylmuramoyl-L-alanine amidase
BAR1_RS10210	COG0436	Aminotransferase
BAR1_RS10225	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BAR1_RS10235	COG0156	8-amino-7-oxononanoate synthase activity
BAR1_RS10275	COG0776	regulation of translation
BAR1_RS10280	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BAR1_RS10285	COG0343	queuine tRNA-ribosyltransferase activity
BAR1_RS10290	COG2154	pterin-4-alpha-carbinolamine dehydratase
BAR1_RS10295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BAR1_RS10305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BAR1_RS10315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BAR1_RS10330	COG0275	rRNA processing
BAR1_RS10335	COG2001	Belongs to the MraZ family
BAR1_RS10340	COG0489	protein tyrosine kinase activity
BAR1_RS10370	COG1304	FMN binding
BAR1_RS10375	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BAR1_RS10405	COG0131	Imidazoleglycerol-phosphate dehydratase
BAR1_RS10410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BAR1_RS10425	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BAR1_RS10430	COG1238	metal cluster binding
BAR1_RS10445	COG0107	imidazoleglycerol-phosphate synthase activity
BAR1_RS10450	COG0140	phosphoribosyl-ATP diphosphatase activity
BAR1_RS10470	COG1832	CoA-binding protein
BAR1_RS10475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BAR1_RS10490	COG2873	o-acetylhomoserine
BAR1_RS10495	COG2968	Membrane
BAR1_RS10515	COG1522	sequence-specific DNA binding
BAR1_RS10520	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BAR1_RS10525	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BAR1_RS10530	COG1329	Transcriptional regulator
BAR1_RS10535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BAR1_RS10540	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BAR1_RS10550	COG0457	Tetratricopeptide repeat
BAR1_RS10565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BAR1_RS10565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BAR1_RS10570	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BAR1_RS10575	COG1914	H( )-stimulated, divalent metal cation uptake system
BAR1_RS10590	COG0432	Pfam Uncharacterised protein family UPF0047
BAR1_RS10605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BAR1_RS10610	COG0358	DNA primase activity
BAR1_RS10620	COG0446	pyridine nucleotide-disulphide oxidoreductase
BAR1_RS10620	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BAR1_RS10625	COG4311	Sarcosine oxidase, delta subunit
BAR1_RS10630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BAR1_RS10635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BAR1_RS10660	COG1309	transcriptional regulator
BAR1_RS10680	COG1335	isochorismatase
BAR1_RS10685	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BAR1_RS10685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BAR1_RS10710	COG0546	phosphoglycolate phosphatase activity
BAR1_RS10725	COG0457	Tetratricopeptide repeat
BAR1_RS10795	COG0784	Response regulator, receiver
BAR1_RS10795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BAR1_RS10835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BAR1_RS10915	COG1250	3-hydroxyacyl-CoA dehydrogenase
BAR1_RS10915	COG0824	Thioesterase
BAR1_RS10935	COG0667	Aldo Keto reductase
BAR1_RS10965	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BAR1_RS10970	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BAR1_RS10970	COG4124	Belongs to the glycosyl hydrolase 26 family
BAR1_RS10980	COG0187	DNA topoisomerase II activity
BAR1_RS10990	COG1136	(ABC) transporter
BAR1_RS11005	COG0442	prolyl-tRNA aminoacylation
BAR1_RS11010	COG0628	permease
BAR1_RS11025	COG0248	Ppx GppA phosphatase
BAR1_RS11045	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BAR1_RS11050	COG0456	acetyltransferase
BAR1_RS11060	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BAR1_RS11065	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BAR1_RS11065	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BAR1_RS11085	COG4770	biotin carboxylase activity
BAR1_RS11115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BAR1_RS11125	COG2814	Major facilitator Superfamily
BAR1_RS11130	COG1396	sequence-specific DNA binding
BAR1_RS11130	COG3800	Transcriptional regulator
BAR1_RS11135	COG1073	alpha beta
BAR1_RS11175	COG1309	transcriptional regulator
BAR1_RS11200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BAR1_RS11215	COG0217	transcriptional regulatory protein
BAR1_RS11225	COG0490	domain, Protein
BAR1_RS11225	COG0471	metal ion transport
BAR1_RS11235	COG2197	response regulator
BAR1_RS11265	COG0471	metal ion transport
BAR1_RS11265	COG3273	potassium ion transport
BAR1_RS11275	COG1692	metallophosphoesterase
BAR1_RS11280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BAR1_RS11285	COG2239	Acts as a magnesium transporter
BAR1_RS11290	COG0402	S-adenosylhomocysteine deaminase activity
BAR1_RS11300	COG0483	inositol monophosphate 1-phosphatase activity
BAR1_RS11310	COG0604	alcohol dehydrogenase
BAR1_RS11310	COG3321	synthase
BAR1_RS11310	COG1028	Short-chain dehydrogenase reductase Sdr
BAR1_RS11320	COG1490	D-aminoacyl-tRNA deacylase activity
BAR1_RS11325	COG2340	Cysteine-rich secretory protein family
BAR1_RS11330	COG2824	Alkylphosphonate utilization operon protein PhnA
BAR1_RS11335	COG1309	transcriptional regulator
BAR1_RS11345	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BAR1_RS11355	COG1530	ribonuclease E activity
BAR1_RS11365	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BAR1_RS11380	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BAR1_RS11390	COG1840	ABC-type Fe3 transport system, periplasmic component
BAR1_RS11395	COG3842	ATPase activity
BAR1_RS11460	COG1024	Enoyl-CoA hydratase
BAR1_RS11460	COG1250	3-hydroxyacyl-CoA dehydrogenase
BAR1_RS11465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BAR1_RS11470	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BAR1_RS11480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BAR1_RS11485	COG0037	tRNA processing
BAR1_RS11495	COG2885	chlorophyll binding
BAR1_RS11510	COG0848	biopolymer transport protein
BAR1_RS11520	COG0824	Thioesterase
BAR1_RS11530	COG2255	four-way junction helicase activity
BAR1_RS11535	COG0632	four-way junction helicase activity
BAR1_RS11540	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BAR1_RS11560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BAR1_RS11570	COG2391	methyltransferase activity
BAR1_RS11575	COG0506	proline dehydrogenase activity
BAR1_RS11590	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BAR1_RS11610	COG1183	phosphatidylcholine synthase activity
BAR1_RS11620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BAR1_RS11625	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BAR1_RS11640	COG3768	UPF0283 membrane protein
BAR1_RS11645	COG3106	COG3106 Predicted ATPase
BAR1_RS11650	COG0101	tRNA pseudouridine synthase activity
BAR1_RS11655	COG0402	S-adenosylhomocysteine deaminase activity
BAR1_RS11660	COG1079	Belongs to the binding-protein-dependent transport system permease family
BAR1_RS11665	COG4603	Belongs to the binding-protein-dependent transport system permease family
BAR1_RS11670	COG3845	ABC transporter
BAR1_RS11675	COG1744	ABC transporter substrate-binding protein PnrA-like
BAR1_RS11690	COG0395	ABC-type sugar transport system, permease component
BAR1_RS11695	COG1175	transmembrane transport
BAR1_RS11700	COG1653	transport
BAR1_RS11705	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BAR1_RS11715	COG2188	Transcriptional regulator
BAR1_RS11720	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BAR1_RS11725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BAR1_RS11730	COG0583	DNA-binding transcription factor activity
BAR1_RS11745	COG1335	isochorismatase
BAR1_RS11750	COG1917	Cupin 2, conserved barrel domain protein
BAR1_RS11750	COG2207	Transcriptional regulator
BAR1_RS11755	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BAR1_RS11765	COG3220	belongs to the UPF0276 family
BAR1_RS11785	COG1393	Belongs to the ArsC family
BAR1_RS11790	COG1278	Cold shock
BAR1_RS11795	COG1278	Cold shock
BAR1_RS11805	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BAR1_RS11815	COG1846	Transcriptional regulator
BAR1_RS11845	COG0534	Mate efflux family protein
BAR1_RS11860	COG2326	polyphosphate kinase activity
BAR1_RS11870	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BAR1_RS11875	COG1088	dTDP-glucose 4,6-dehydratase activity
BAR1_RS11880	COG1091	dTDP-4-dehydrorhamnose reductase activity
BAR1_RS11895	COG0493	'glutamate synthase
BAR1_RS11900	COG0649	NAD binding
BAR1_RS11905	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BAR1_RS11905	COG0649	NAD binding
BAR1_RS11910	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BAR1_RS11915	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BAR1_RS11920	COG0651	ATP synthesis coupled electron transport
BAR1_RS11925	COG1006	Multisubunit Na H antiporter MnhC subunit
BAR1_RS11930	COG2111	Na H antiporter
BAR1_RS11945	COG2212	antiporter activity
BAR1_RS11950	COG1863	multisubunit Na H antiporter MnhE subunit
BAR1_RS11955	COG3971	2-oxopent-4-enoate hydratase activity
BAR1_RS11960	COG0179	Fumarylacetoacetate (FAA) hydrolase
BAR1_RS11965	COG3384	dioxygenase
BAR1_RS11985	COG5441	Belongs to the UPF0261 family
BAR1_RS11990	COG1012	belongs to the aldehyde dehydrogenase family
BAR1_RS12010	COG1414	Transcriptional regulator
BAR1_RS12025	COG0174	glutamine synthetase
BAR1_RS12110	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BAR1_RS12115	COG2218	PFAM glutamate synthase alpha subunit domain protein
BAR1_RS12120	COG0069	glutamate synthase activity
BAR1_RS12125	COG0174	glutamine synthetase
BAR1_RS12130	COG2205	protein histidine kinase activity
BAR1_RS12315	COG0740	serine-type endopeptidase activity
BAR1_RS12395	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BAR1_RS12445	COG1061	Type III restriction enzyme res subunit
BAR1_RS12480	COG3177	Filamentation induced by cAMP protein fic
BAR1_RS12510	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BAR1_RS12530	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BAR1_RS12540	COG0084	hydrolase, TatD family'
BAR1_RS12545	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BAR1_RS12585	COG3842	ATPase activity
BAR1_RS12650	COG2135	peptidase activity
BAR1_RS12655	COG0737	Belongs to the 5'-nucleotidase family
BAR1_RS12665	COG0167	dihydroorotate dehydrogenase activity
BAR1_RS12675	COG0534	Mate efflux family protein
BAR1_RS12705	COG1960	acyl-CoA dehydrogenase activity
BAR1_RS12720	COG0183	Belongs to the thiolase family
BAR1_RS12730	COG1024	Enoyl-CoA hydratase
BAR1_RS12730	COG1250	3-hydroxyacyl-CoA dehydrogenase
BAR1_RS12740	COG0318	PFAM AMP-dependent synthetase and ligase
BAR1_RS12750	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BAR1_RS12755	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BAR1_RS12760	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BAR1_RS12770	COG0295	cytidine deaminase activity
BAR1_RS12775	COG0280	phosphate acetyltransferase
BAR1_RS12775	COG0281	malic enzyme
BAR1_RS12785	COG5002	protein histidine kinase activity
BAR1_RS12785	COG0784	Response regulator, receiver
BAR1_RS12785	COG2198	Histidine kinase
BAR1_RS12790	COG2204	response regulator
BAR1_RS12795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BAR1_RS12800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BAR1_RS12855	COG0481	GTPase activity
BAR1_RS12860	COG4650	regulator
BAR1_RS12885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BAR1_RS12905	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BAR1_RS12915	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BAR1_RS12920	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BAR1_RS12925	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BAR1_RS12930	COG0124	histidyl-tRNA synthetase
BAR1_RS12935	COG0840	transmembrane signaling receptor activity
BAR1_RS12970	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BAR1_RS12980	COG3845	ABC transporter
BAR1_RS12985	COG4603	Belongs to the binding-protein-dependent transport system permease family
BAR1_RS12990	COG1079	Belongs to the binding-protein-dependent transport system permease family
BAR1_RS12995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BAR1_RS13005	COG0667	Aldo Keto reductase
BAR1_RS13010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BAR1_RS13020	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BAR1_RS13035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BAR1_RS13055	COG1396	sequence-specific DNA binding
BAR1_RS13065	COG0559	Belongs to the binding-protein-dependent transport system permease family
BAR1_RS13095	COG0277	FAD linked oxidase domain protein
BAR1_RS13100	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BAR1_RS13105	COG1132	(ABC) transporter
BAR1_RS13115	COG1703	isobutyryl-CoA mutase activity
BAR1_RS13120	COG1643	Atp-dependent helicase
BAR1_RS13135	COG3118	belongs to the thioredoxin family
BAR1_RS13150	COG0071	Belongs to the small heat shock protein (HSP20) family
BAR1_RS13160	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BAR1_RS13165	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BAR1_RS13180	COG0459	protein refolding
BAR1_RS13185	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BAR1_RS13190	COG2267	carboxylic ester hydrolase activity
BAR1_RS13205	COG1227	inorganic diphosphatase activity
BAR1_RS13215	COG2030	dehydratase
BAR1_RS13220	COG0196	riboflavin kinase activity
BAR1_RS13225	COG2983	Belongs to the UPF0260 family
BAR1_RS13250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BAR1_RS13255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BAR1_RS13260	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BAR1_RS13265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BAR1_RS13270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BAR1_RS13310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BAR1_RS13330	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BAR1_RS13355	COG0287	Prephenate dehydrogenase
BAR1_RS13360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BAR1_RS13370	COG1522	sequence-specific DNA binding
BAR1_RS13375	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BAR1_RS13385	COG4106	trans-aconitate 2-methyltransferase activity
BAR1_RS13395	COG1435	thymidine kinase activity
BAR1_RS13400	COG2358	TRAP transporter, solute receptor (TAXI family
BAR1_RS13420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BAR1_RS13445	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BAR1_RS13455	COG1496	oxidoreductase activity
BAR1_RS13460	COG1522	sequence-specific DNA binding
BAR1_RS13465	COG0492	ferredoxin-NADP+ reductase activity
BAR1_RS13470	COG0529	Catalyzes the synthesis of activated sulfate
BAR1_RS13470	COG2046	Belongs to the sulfate adenylyltransferase family
BAR1_RS13490	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BAR1_RS13490	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BAR1_RS13495	COG0509	glycine decarboxylation via glycine cleavage system
BAR1_RS13500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BAR1_RS13515	COG0826	peptidase U32
BAR1_RS13520	COG0752	glycyl-tRNA synthetase alpha subunit
BAR1_RS13530	COG0751	glycine-tRNA ligase activity
BAR1_RS13535	COG0574	Belongs to the PEP-utilizing enzyme family
BAR1_RS13535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BAR1_RS13545	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BAR1_RS13550	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BAR1_RS13555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BAR1_RS13565	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BAR1_RS13570	COG1522	sequence-specific DNA binding
BAR1_RS13575	COG1522	sequence-specific DNA binding
BAR1_RS13580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BAR1_RS13585	COG1752	Esterase of the alpha-beta hydrolase superfamily
BAR1_RS13600	COG1802	Transcriptional regulator
BAR1_RS13610	COG0505	Belongs to the CarA family
BAR1_RS13630	COG0076	glutamate decarboxylase activity
BAR1_RS13640	COG1280	lysine exporter protein (LysE YggA)
BAR1_RS13650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BAR1_RS13655	COG1469	GTP cyclohydrolase I activity
BAR1_RS13665	COG0625	glutathione transferase activity
BAR1_RS13690	COG0552	protein localization to endoplasmic reticulum
BAR1_RS13705	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BAR1_RS13710	COG1570	exodeoxyribonuclease VII activity
BAR1_RS13715	COG0151	Belongs to the GarS family
BAR1_RS13740	COG1132	(ABC) transporter
BAR1_RS13755	COG3228	Belongs to the MtfA family
BAR1_RS13785	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BAR1_RS13795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BAR1_RS13805	COG1492	cobalamin metabolic process
BAR1_RS13820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BAR1_RS13825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BAR1_RS13855	COG2089	acid synthase
BAR1_RS13865	COG1519	Transferase
BAR1_RS13875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BAR1_RS13925	COG2267	carboxylic ester hydrolase activity
BAR1_RS13935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BAR1_RS13945	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BAR1_RS13950	COG0702	epimerase
BAR1_RS13970	COG0321	lipoyl(octanoyl) transferase activity
BAR1_RS13975	COG3474	cytochrome
BAR1_RS14005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BAR1_RS14025	COG0181	hydroxymethylbilane synthase activity
BAR1_RS14030	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BAR1_RS14055	COG0408	coproporphyrinogen oxidase activity
BAR1_RS14075	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BAR1_RS14080	COG1686	Belongs to the peptidase S11 family
BAR1_RS14105	COG0348	domain, Protein
BAR1_RS14110	COG2010	Cytochrome c
BAR1_RS14140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BAR1_RS14145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BAR1_RS14150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BAR1_RS14160	COG4172	Belongs to the ABC transporter superfamily
BAR1_RS14165	COG4239	(ABC) transporter, permease
BAR1_RS14170	COG4174	ABC transporter (Permease)
BAR1_RS14175	COG4166	transmembrane transport
BAR1_RS14190	COG1605	Chorismate mutase
BAR1_RS14190	COG0077	Prephenate dehydratase
BAR1_RS14205	COG0737	Belongs to the 5'-nucleotidase family
BAR1_RS14225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BAR1_RS14235	COG1309	transcriptional regulator
BAR1_RS14255	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BAR1_RS14260	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BAR1_RS14280	COG0789	Transcriptional regulator
BAR1_RS14320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BAR1_RS14325	COG0813	purine-nucleoside phosphorylase activity
BAR1_RS14335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BAR1_RS14380	COG2030	dehydratase
BAR1_RS14395	COG2301	Belongs to the HpcH HpaI aldolase family
BAR1_RS14405	COG0039	L-malate dehydrogenase activity
BAR1_RS14415	COG0045	succinate-CoA ligase (ADP-forming) activity
BAR1_RS14445	COG0508	dehydrogenase complex catalyzes the overall conversion of
BAR1_RS14530	COG0747	negative chemotaxis
BAR1_RS14535	COG0601	transmembrane transport
BAR1_RS14540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAR1_RS14545	COG0668	transmembrane transport
BAR1_RS14550	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BAR1_RS14565	COG0438	transferase activity, transferring glycosyl groups
BAR1_RS14570	COG1177	transmembrane transport
BAR1_RS14575	COG1176	ABC-type spermidine putrescine transport system, permease component I
BAR1_RS14580	COG3842	ATPase activity
BAR1_RS14590	COG1802	Transcriptional regulator
BAR1_RS14600	COG0765	amino acid transport
BAR1_RS14605	COG1126	abc transporter atp-binding protein
BAR1_RS14610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAR1_RS14615	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BAR1_RS14620	COG1012	belongs to the aldehyde dehydrogenase family
BAR1_RS14635	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BAR1_RS14640	COG1185	polyribonucleotide nucleotidyltransferase activity
BAR1_RS14650	COG0450	alkyl hydroperoxide reductase
BAR1_RS14665	COG0564	pseudouridine synthase activity
BAR1_RS14690	COG0183	Belongs to the thiolase family
BAR1_RS14730	COG1674	ftsk spoiiie
BAR1_RS14730	COG1674	ftsk spoiiie
BAR1_RS14735	COG0436	Aminotransferase
BAR1_RS14740	COG0154	amidase activity
BAR1_RS14745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BAR1_RS14750	COG2835	tetraacyldisaccharide 4'-kinase activity
BAR1_RS14770	COG0745	RESPONSE REGULATOR receiver
BAR1_RS14800	COG0495	leucyl-tRNA aminoacylation
BAR1_RS14820	COG1196	nuclear chromosome segregation
BAR1_RS14820	COG3264	Mechanosensitive ion channel
BAR1_RS14850	COG0312	modulator of DNA gyrase
BAR1_RS14885	COG1194	a g-specific adenine glycosylase
BAR1_RS14920	COG0765	amino acid transport
BAR1_RS14925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAR1_RS14930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BAR1_RS14935	COG0756	dUTP diphosphatase activity
BAR1_RS14940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BAR1_RS14955	COG0588	phosphoglycerate mutase activity
BAR1_RS14970	COG0606	chelatase, subunit chli
BAR1_RS14975	COG0657	acetylesterase activity
BAR1_RS14990	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BAR1_RS15000	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BAR1_RS15015	COG0180	Tryptophanyl-tRNA synthetase
BAR1_RS15020	COG2514	catechol 2,3-dioxygenase activity
BAR1_RS15030	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BAR1_RS15035	COG1214	PFAM Peptidase M22, glycoprotease
BAR1_RS15045	COG1744	ABC transporter substrate-binding protein PnrA-like
BAR1_RS15050	COG3845	ABC transporter
BAR1_RS15055	COG4603	Belongs to the binding-protein-dependent transport system permease family
BAR1_RS15060	COG1079	Belongs to the binding-protein-dependent transport system permease family
BAR1_RS15065	COG0730	response to heat
BAR1_RS15075	COG4221	oxidoreductase activity
BAR1_RS15085	COG0604	alcohol dehydrogenase
BAR1_RS15090	COG2937	Belongs to the GPAT DAPAT family
BAR1_RS15105	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BAR1_RS15105	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BAR1_RS15120	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BAR1_RS15130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BAR1_RS15135	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BAR1_RS15150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BAR1_RS15160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BAR1_RS15170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BAR1_RS15175	COG0303	'Molybdopterin
BAR1_RS15180	COG0746	molybdenum cofactor guanylyltransferase activity
BAR1_RS15185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BAR1_RS15220	COG1960	acyl-CoA dehydrogenase activity
BAR1_RS15225	COG0009	L-threonylcarbamoyladenylate synthase
BAR1_RS15230	COG1678	Uncharacterized ACR, COG1678
BAR1_RS15255	COG0521	Mo-molybdopterin cofactor biosynthetic process
BAR1_RS15260	COG1573	uracil-dna glycosylase
BAR1_RS15265	COG0540	Belongs to the ATCase OTCase family
BAR1_RS15285	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BAR1_RS15290	COG3239	Fatty acid desaturase
BAR1_RS15320	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BAR1_RS15335	COG0314	molybdopterin synthase activity
BAR1_RS15345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BAR1_RS15350	COG0322	excinuclease ABC activity
BAR1_RS15365	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BAR1_RS15365	COG0616	signal peptide processing
BAR1_RS15370	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BAR1_RS15380	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BAR1_RS15415	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BAR1_RS15455	COG1086	Polysaccharide biosynthesis protein
BAR1_RS15475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BAR1_RS15480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BAR1_RS15500	COG5002	protein histidine kinase activity
BAR1_RS15525	COG0437	4 iron, 4 sulfur cluster binding
BAR1_RS15530	COG3383	formate dehydrogenase (NAD+) activity
BAR1_RS15530	COG0243	molybdopterin cofactor binding
BAR1_RS15565	COG0489	protein tyrosine kinase activity
BAR1_RS15585	COG3842	ATPase activity
BAR1_RS15605	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BAR1_RS15610	COG0028	Belongs to the TPP enzyme family
BAR1_RS15615	COG0022	dehydrogenase e1 component
BAR1_RS15620	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BAR1_RS15635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BAR1_RS15635	COG0517	IMP dehydrogenase activity
BAR1_RS15640	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BAR1_RS15645	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BAR1_RS15665	COG1137	ATPase activity
BAR1_RS15670	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BAR1_RS15675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BAR1_RS15680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAR1_RS15750	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BAR1_RS15760	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BAR1_RS15760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BAR1_RS15820	COG0747	negative chemotaxis
BAR1_RS15825	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BAR1_RS15870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAR1_RS15900	COG3191	aminopeptidase activity
BAR1_RS15930	COG2304	oxidoreductase activity
BAR1_RS15935	COG0071	Belongs to the small heat shock protein (HSP20) family
BAR1_RS15940	COG3591	Belongs to the peptidase S1B family
BAR1_RS15945	COG0247	lactate metabolic process
BAR1_RS15950	COG0277	FAD linked oxidase domain protein
BAR1_RS15955	COG0277	FAD linked oxidase domain protein
BAR1_RS15990	COG0714	Associated with various cellular activities
BAR1_RS16000	COG3622	Belongs to the hyi family
BAR1_RS16010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BAR1_RS16010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BAR1_RS16040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BAR1_RS16045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BAR1_RS16050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BAR1_RS16065	COG0697	spore germination
BAR1_RS16070	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BAR1_RS16080	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BAR1_RS16085	COG0356	it plays a direct role in the translocation of protons across the membrane
BAR1_RS16110	COG1858	cytochrome C peroxidase
BAR1_RS16115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BAR1_RS16130	COG0228	four-way junction DNA binding
BAR1_RS16135	COG0778	Nitroreductase
BAR1_RS16140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BAR1_RS16150	COG0335	large ribosomal subunit rRNA binding
BAR1_RS16155	COG0254	rRNA binding
BAR1_RS16160	COG1192	Involved in chromosome partitioning
BAR1_RS16165	COG0300	oxidoreductase activity
BAR1_RS16195	COG1250	3-hydroxyacyl-CoA dehydrogenase
BAR1_RS16205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAR1_RS16225	COG2205	protein histidine kinase activity
BAR1_RS16230	COG0745	RESPONSE REGULATOR receiver
BAR1_RS16265	COG1381	Involved in DNA repair and RecF pathway recombination
BAR1_RS16275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BAR1_RS16285	COG0681	Belongs to the peptidase S26 family
BAR1_RS16300	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BAR1_RS16310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BAR1_RS16315	COG1758	RNA polymerase activity
BAR1_RS16320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BAR1_RS16330	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BAR1_RS16340	COG0328	RNA-DNA hybrid ribonuclease activity
BAR1_RS16350	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BAR1_RS16355	COG0242	peptide deformylase activity
BAR1_RS16360	COG0242	peptide deformylase activity
BAR1_RS16365	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BAR1_RS16370	COG0589	response to stress
BAR1_RS16375	COG0659	secondary active sulfate transmembrane transporter activity
BAR1_RS16390	COG1959	2 iron, 2 sulfur cluster binding
BAR1_RS16395	COG1271	oxidase subunit
BAR1_RS16400	COG1294	oxidase, subunit
BAR1_RS16410	COG1028	Short-chain dehydrogenase reductase Sdr
BAR1_RS16415	COG4608	Belongs to the ABC transporter superfamily
BAR1_RS16420	COG0444	Belongs to the ABC transporter superfamily
BAR1_RS16425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAR1_RS16430	COG0601	transmembrane transport
BAR1_RS16435	COG0747	negative chemotaxis
BAR1_RS16445	COG0583	DNA-binding transcription factor activity
BAR1_RS16455	COG0288	reversible hydration of carbon dioxide
BAR1_RS16465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BAR1_RS16470	COG0791	NLP P60 protein
BAR1_RS16480	COG3327	negative regulation of DNA-templated transcription, initiation
BAR1_RS16485	COG1012	belongs to the aldehyde dehydrogenase family
BAR1_RS16485	COG2030	dehydratase
BAR1_RS16490	COG2050	protein possibly involved in aromatic compounds catabolism
BAR1_RS16495	COG0183	Belongs to the thiolase family
BAR1_RS16530	COG0535	radical SAM domain protein
BAR1_RS16550	COG3391	amine dehydrogenase activity
BAR1_RS16555	COG2010	Cytochrome c
BAR1_RS16560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BAR1_RS16565	COG2010	Cytochrome c
BAR1_RS16580	COG0714	Associated with various cellular activities
BAR1_RS16590	COG1845	cytochrome c oxidase, subunit III
BAR1_RS16600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BAR1_RS16615	COG1671	Belongs to the UPF0178 family
BAR1_RS16625	COG2423	ornithine cyclodeaminase activity
BAR1_RS16635	COG0596	Alpha beta hydrolase
BAR1_RS16635	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BAR1_RS16635	COG2226	methyltransferase
BAR1_RS16640	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BAR1_RS16645	COG0285	dihydrofolate synthase activity
BAR1_RS16650	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BAR1_RS16670	COG0129	dihydroxy-acid dehydratase activity
BAR1_RS16690	COG0446	pyridine nucleotide-disulphide oxidoreductase
BAR1_RS16690	COG1902	pentaerythritol trinitrate reductase activity
BAR1_RS16695	COG0583	DNA-binding transcription factor activity
BAR1_RS16715	COG1546	Belongs to the CinA family
BAR1_RS16715	COG1058	Belongs to the CinA family
BAR1_RS16720	COG1489	DNA binding
BAR1_RS16725	COG0024	Methionine aminopeptidase
BAR1_RS16750	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BAR1_RS16760	COG2124	cytochrome p450
BAR1_RS16770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BAR1_RS16810	COG0826	peptidase U32
BAR1_RS16830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BAR1_RS16835	COG0513	Belongs to the DEAD box helicase family
BAR1_RS16850	COG2875	Belongs to the precorrin methyltransferase family
BAR1_RS16890	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BAR1_RS16985	COG1846	Transcriptional regulator
BAR1_RS17000	COG0631	protein serine/threonine phosphatase activity
BAR1_RS17010	COG0515	serine threonine protein kinase
BAR1_RS17010	COG2815	serine threonine protein kinase
BAR1_RS17055	COG1215	transferase activity, transferring glycosyl groups
BAR1_RS17075	COG0443	Heat shock 70 kDa protein
BAR1_RS17085	COG2003	Belongs to the UPF0758 family
BAR1_RS17100	COG0653	protein targeting
BAR1_RS17105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BAR1_RS17110	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BAR1_RS17115	COG0494	nUDIX hydrolase
BAR1_RS17120	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BAR1_RS17135	COG0779	Required for maturation of 30S ribosomal subunits
BAR1_RS17140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BAR1_RS17175	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BAR1_RS17185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BAR1_RS17200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BAR1_RS17235	COG3034	peptidoglycan biosynthetic process
BAR1_RS17240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BAR1_RS17245	COG0617	tRNA 3'-terminal CCA addition
BAR1_RS17250	COG0494	nUDIX hydrolase
BAR1_RS17275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BAR1_RS17285	COG0137	argininosuccinate synthase activity
BAR1_RS17300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BAR1_RS17305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BAR1_RS17310	COG0281	malic enzyme
BAR1_RS17310	COG0280	phosphate acetyltransferase
BAR1_RS17315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BAR1_RS17320	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BAR1_RS17325	COG1420	regulation of RNA biosynthetic process
BAR1_RS17330	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BAR1_RS17335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BAR1_RS17340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BAR1_RS17360	COG0357	Ribosomal RNA small subunit methyltransferase G
BAR1_RS17365	COG0445	tRNA wobble uridine modification
BAR1_RS17370	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BAR1_RS17375	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BAR1_RS17380	COG1981	membrane
BAR1_RS17385	COG0424	maF-like protein
BAR1_RS17390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BAR1_RS17395	COG0237	dephospho-CoA kinase activity
BAR1_RS17400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BAR1_RS17435	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BAR1_RS17445	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BAR1_RS17455	COG1074	ATP-dependent DNA helicase activity
BAR1_RS17465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BAR1_RS17470	COG3178	'Phosphotransferase
BAR1_RS17475	COG0802	atpase or kinase
BAR1_RS17480	COG2205	protein histidine kinase activity
BAR1_RS17490	COG1999	signal sequence binding
BAR1_RS17495	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BAR1_RS17515	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BAR1_RS17525	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BAR1_RS17555	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BAR1_RS17560	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BAR1_RS17595	COG1175	transmembrane transport
BAR1_RS17600	COG0395	ABC-type sugar transport system, permease component
BAR1_RS17605	COG3842	ATPase activity
BAR1_RS17615	COG1360	Flagellar Motor Protein
BAR1_RS17625	COG1749	Flagellar hook protein flgE
BAR1_RS17640	COG1706	bacterial-type flagellum-dependent cell motility
BAR1_RS17645	COG1338	Plays a role in the flagellum-specific transport system
BAR1_RS17650	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BAR1_RS17660	COG1766	The M ring may be actively involved in energy transduction
BAR1_RS17680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BAR1_RS17695	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BAR1_RS17705	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BAR1_RS17720	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BAR1_RS17730	COG4786	Flagellar basal body rod
BAR1_RS17735	COG4786	Flagellar basal body rod
BAR1_RS17740	COG1987	bacterial-type flagellum assembly
BAR1_RS17745	COG1677	Flagellar hook-basal body complex protein FliE
BAR1_RS17750	COG1558	bacterial-type flagellum-dependent cell motility
BAR1_RS17755	COG1815	bacterial-type flagellum-dependent cell motility
BAR1_RS17770	COG5443	negative regulation of bacterial-type flagellum assembly
BAR1_RS17800	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BAR1_RS17810	COG2226	methyltransferase
BAR1_RS17815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BAR1_RS17820	COG1024	Enoyl-CoA hydratase
BAR1_RS17825	COG0268	Binds directly to 16S ribosomal RNA